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Search of human proteins with 6806913
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|6806913 centaurin, alpha 1 [Homo sapiens]
(374 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|6806913 centaurin, alpha 1 [Homo sapiens] 786 0.0
gi|8923763 centaurin-alpha 2 protein [Homo sapiens] 464 e-131
gi|110227613 centaurin, gamma 3 isoform a [Homo sapiens] 97 2e-20
gi|7661880 centaurin beta1 [Homo sapiens] 96 5e-20
gi|113204622 stromal membrane-associated GTPase-activating prote... 96 5e-20
gi|21264558 stromal membrane-associated GTPase-activating protei... 96 5e-20
gi|218563749 ArfGAP with coiled-coil, ankyrin repeat and PH doma... 95 1e-19
gi|23943872 small ArfGAP2 [Homo sapiens] 95 1e-19
gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens] 94 2e-19
gi|7661962 centaurin, gamma 1 isoform PIKE-S [Homo sapiens] 94 2e-19
gi|187608516 centaurin, beta 2 [Homo sapiens] 92 1e-18
gi|117956373 ArfGAP with GTPase domain, ankyrin repeat and PH do... 89 5e-18
gi|156104893 ArfGAP with GTPase domain, ankyrin repeat and PH do... 89 6e-18
gi|80978934 centaurin, gamma 2 isoform 2 [Homo sapiens] 89 8e-18
gi|80978930 centaurin, gamma 2 isoform 1 [Homo sapiens] 89 8e-18
gi|166851846 centaurin, gamma-like family, member 3 [Homo sapiens] 87 2e-17
gi|206597513 ArfGAP with RhoGAP domain, ankyrin repeat and PH do... 87 2e-17
gi|92091600 ArfGAP with RhoGAP domain, ankyrin repeat and PH dom... 87 2e-17
gi|117956371 ArfGAP with GTPase domain, ankyrin repeat and PH do... 87 3e-17
gi|148806877 ankyrin repeat and GTPase domain Arf GTPase activat... 86 4e-17
gi|46094081 development and differentiation enhancing factor 1 [... 85 9e-17
gi|239744074 PREDICTED: ArfGAP with GTPase domain, ankyrin repea... 84 2e-16
gi|239744064 PREDICTED: ArfGAP with GTPase domain, ankyrin repea... 84 2e-16
gi|221136914 ArfGAP with GTPase domain, ankyrin repeat and PH do... 84 3e-16
gi|221307473 ArfGAP with SH3 domain, ankyrin repeat and PH domai... 79 9e-15
gi|19923540 ArfGAP with SH3 domain, ankyrin repeat and PH domain... 79 9e-15
gi|206597522 ArfGAP with SH3 domain, ankyrin repeat and PH domai... 70 3e-12
gi|4502249 ArfGAP with SH3 domain, ankyrin repeat and PH domain ... 70 3e-12
gi|28416436 ADP-ribosylation factor GTPase activating protein 1 ... 69 5e-12
gi|8922652 ADP-ribosylation factor GTPase activating protein 1 i... 69 5e-12
>gi|6806913 centaurin, alpha 1 [Homo sapiens]
Length = 374
Score = 786 bits (2029), Expect = 0.0
Identities = 374/374 (100%), Positives = 374/374 (100%)
Query: 1 MAKERRRAVLELLQRPGNARCADCGAPDPDWASYTLGVFICLSCSGIHRNIPQVSKVKSV 60
MAKERRRAVLELLQRPGNARCADCGAPDPDWASYTLGVFICLSCSGIHRNIPQVSKVKSV
Sbjct: 1 MAKERRRAVLELLQRPGNARCADCGAPDPDWASYTLGVFICLSCSGIHRNIPQVSKVKSV 60
Query: 61 RLDAWEEAQVEFMASHGNDAARARFESKVPSFYYRPTPSDCQLLREQWIRAKYERQEFIY 120
RLDAWEEAQVEFMASHGNDAARARFESKVPSFYYRPTPSDCQLLREQWIRAKYERQEFIY
Sbjct: 61 RLDAWEEAQVEFMASHGNDAARARFESKVPSFYYRPTPSDCQLLREQWIRAKYERQEFIY 120
Query: 121 PEKQEPYSAGYREGFLWKRGRDNGQFLSRKFVLTEREGALKYFNRNDAKEPKAVMKIEHL 180
PEKQEPYSAGYREGFLWKRGRDNGQFLSRKFVLTEREGALKYFNRNDAKEPKAVMKIEHL
Sbjct: 121 PEKQEPYSAGYREGFLWKRGRDNGQFLSRKFVLTEREGALKYFNRNDAKEPKAVMKIEHL 180
Query: 181 NATFQPAKIGHPHGLQVTYLKDNSTRNIFIYHEDGKEIVDWFNALRAARFHYLQVAFPGA 240
NATFQPAKIGHPHGLQVTYLKDNSTRNIFIYHEDGKEIVDWFNALRAARFHYLQVAFPGA
Sbjct: 181 NATFQPAKIGHPHGLQVTYLKDNSTRNIFIYHEDGKEIVDWFNALRAARFHYLQVAFPGA 240
Query: 241 SDADLVPKLSRNYLKEGYMEKTGPKQTEGFRKRWFTMDDRRLMYFKDPLDAFARGEVFIG 300
SDADLVPKLSRNYLKEGYMEKTGPKQTEGFRKRWFTMDDRRLMYFKDPLDAFARGEVFIG
Sbjct: 241 SDADLVPKLSRNYLKEGYMEKTGPKQTEGFRKRWFTMDDRRLMYFKDPLDAFARGEVFIG 300
Query: 301 SKESGYTVLHGFPPSTQGHHWPHGITIVTPDRKFLFACETESDQREWVAAFQKAVDRPML 360
SKESGYTVLHGFPPSTQGHHWPHGITIVTPDRKFLFACETESDQREWVAAFQKAVDRPML
Sbjct: 301 SKESGYTVLHGFPPSTQGHHWPHGITIVTPDRKFLFACETESDQREWVAAFQKAVDRPML 360
Query: 361 PQEYAVEAHFKHKP 374
PQEYAVEAHFKHKP
Sbjct: 361 PQEYAVEAHFKHKP 374
>gi|8923763 centaurin-alpha 2 protein [Homo sapiens]
Length = 381
Score = 464 bits (1195), Expect = e-131
Identities = 212/363 (58%), Positives = 277/363 (76%), Gaps = 5/363 (1%)
Query: 3 KERRRAVLELLQRP--GNARCADCGAPDPDWASYTLGVFICLSCSGIHRNIPQVSKVKSV 60
+ ++ +LELL+ P GNA CADCGA DPDWASY LG+FICL+C G+HRN P +S+VKSV
Sbjct: 5 ERNKKRLLELLRAPDTGNAHCADCGAADPDWASYKLGIFICLNCCGVHRNFPDISRVKSV 64
Query: 61 RLDAWEEAQVEFMASHGNDAARARFESKVPSFYYRPTPSDCQLLREQWIRAKYERQEFIY 120
RLD W+++ VEFM +GN +A+FE++VP+FYY P +DC +L+EQWIRAKYER+EF+
Sbjct: 65 RLDFWDDSIVEFMIHNGNLRVKAKFEARVPAFYYIPQANDCLVLKEQWIRAKYERREFM- 123
Query: 121 PEKQEPYSAGYREGFLWKRGRDNGQFLSRKFVLTEREGALKYFNRNDAKEPKAVMKIEHL 180
+ + G REGFLWKRGRDN QFL RKFVL REG LKYF + K PKAV+ I+ L
Sbjct: 124 ADGETISLPGNREGFLWKRGRDNSQFLRRKFVLLAREGLLKYFTKEQGKSPKAVISIKDL 183
Query: 181 NATFQPAKIGHPHGLQVTYLKDNSTRNIFIYHEDGKEIVDWFNALRAARFHYLQVAFPGA 240
NATFQ KIGHPHGLQ+TY +D TRN+F+YHE GKEIVDWFNALRAAR YL++AFP
Sbjct: 184 NATFQTEKIGHPHGLQITYRRDGHTRNLFVYHESGKEIVDWFNALRAARLQYLKMAFPEL 243
Query: 241 SDADLVPKLSRNYLKEGYMEKTGPKQTEGFRKRWFTMD--DRRLMYFKDPLDAFARGEVF 298
+++LVP L+RNYLK+G+MEKTGPKQ E F+KRWF +D +RRL+Y+K+PLDAF +G+VF
Sbjct: 244 PESELVPFLTRNYLKQGFMEKTGPKQKEPFKKRWFALDCHERRLLYYKNPLDAFEQGQVF 303
Query: 299 IGSKESGYTVLHGFPPSTQGHHWPHGITIVTPDRKFLFACETESDQREWVAAFQKAVDRP 358
+G+KE GY P +G+ W G+TIVTP+R+F+ C +E +Q+EW+ + + + P
Sbjct: 304 LGNKEQGYEAYEDLPKGIRGNRWKAGLTIVTPERRFVLTCPSEKEQQEWLESLRGVLSSP 363
Query: 359 MLP 361
+ P
Sbjct: 364 LTP 366
>gi|110227613 centaurin, gamma 3 isoform a [Homo sapiens]
Length = 911
Score = 97.4 bits (241), Expect = 2e-20
Identities = 46/106 (43%), Positives = 68/106 (64%), Gaps = 2/106 (1%)
Query: 17 GNARCADCGAPDPDWASYTLGVFICLSCSGIHRNI-PQVSKVKSVRLDAWEEAQVEFMAS 75
GN+ C DC AP+PDWAS LG +C+ CSGIHR++ +S+V+S+ LD W + M +
Sbjct: 673 GNSFCIDCDAPNPDWASLNLGALMCIECSGIHRHLGAHLSRVRSLDLDDWPPELLAVMTA 732
Query: 76 HGNDAARARFESKVPSFYYRPTPSDCQLLREQWIRAKYERQEFIYP 121
GN A + +E + Y +P P C+ +E+WIRAKYE++ F+ P
Sbjct: 733 MGNALANSVWEGALGG-YSKPGPDACREEKERWIRAKYEQKLFLAP 777
>gi|7661880 centaurin beta1 [Homo sapiens]
Length = 740
Score = 95.9 bits (237), Expect = 5e-20
Identities = 72/206 (34%), Positives = 103/206 (50%), Gaps = 29/206 (14%)
Query: 17 GNARCADCGAPDPDWASYTLGVFICLSCSGIHRNI-PQVSKVKSVRLDAWEEAQVEFMAS 75
GNA+C DC P P+WAS LGV +C+ CSGIHR++ SKV+S+ LD+WE V+ M
Sbjct: 416 GNAQCCDCREPAPEWASINLGVTLCIQCSGIHRSLGVHFSKVRSLTLDSWEPELVKLMCE 475
Query: 76 HGNDAARARFESKVPSF-YYRPTPSDCQLLREQWIRAKYERQEFIYPEKQEPYSAGYREG 134
GN +E++V + +P PS + +E WI AKY ++F+ + P G R G
Sbjct: 476 LGNVIINQIYEARVEAMAVKKPGPSCSRQEKEAWIHAKYVEKKFL---TKLPEIRGRRGG 532
Query: 135 FLWKRGRDNGQ-FLSRKFVLTEREGALKYFNRNDAKEPKAVMKIEHLNATFQPAKIGHP- 192
RGR GQ + K + R G+L R+ + P + H A A GHP
Sbjct: 533 ----RGRPRGQPPVPPKPSIRPRPGSL----RSKPEPPSEDLGSLHPGALLFRAS-GHPP 583
Query: 193 ----------HGLQVTYL---KDNST 205
HG V ++ +DN+T
Sbjct: 584 SLPTMADALAHGADVNWVNGGQDNAT 609
>gi|113204622 stromal membrane-associated GTPase-activating protein
1 isoform A [Homo sapiens]
Length = 467
Score = 95.9 bits (237), Expect = 5e-20
Identities = 49/117 (41%), Positives = 72/117 (61%), Gaps = 5/117 (4%)
Query: 4 ERRRAVL-ELLQRPGNARCADCGAPDPDWASYTLGVFICLSCSGIHRNI-PQVSKVKSVR 61
E+ + +L +LL+ N CADC A P WAS+ +GVFIC+ C+GIHRN+ +S+VKSV
Sbjct: 15 EQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVN 74
Query: 62 LDAWEEAQVEFMASHGNDAARARFESKVPSFYYRPTPSDCQLLREQWIRAKYERQEF 118
LD W Q++ M GN AR +E+ +P + RP E +IR KYE++++
Sbjct: 75 LDQWTAEQIQCMQDMGNTKARLLYEANLPENFRRPQTDQAV---EFFIRDKYEKKKY 128
>gi|21264558 stromal membrane-associated GTPase-activating protein 1
isoform B [Homo sapiens]
Length = 440
Score = 95.9 bits (237), Expect = 5e-20
Identities = 49/117 (41%), Positives = 72/117 (61%), Gaps = 5/117 (4%)
Query: 4 ERRRAVL-ELLQRPGNARCADCGAPDPDWASYTLGVFICLSCSGIHRNI-PQVSKVKSVR 61
E+ + +L +LL+ N CADC A P WAS+ +GVFIC+ C+GIHRN+ +S+VKSV
Sbjct: 15 EQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVN 74
Query: 62 LDAWEEAQVEFMASHGNDAARARFESKVPSFYYRPTPSDCQLLREQWIRAKYERQEF 118
LD W Q++ M GN AR +E+ +P + RP E +IR KYE++++
Sbjct: 75 LDQWTAEQIQCMQDMGNTKARLLYEANLPENFRRPQTDQAV---EFFIRDKYEKKKY 128
>gi|218563749 ArfGAP with coiled-coil, ankyrin repeat and PH domains
3 [Homo sapiens]
Length = 834
Score = 94.7 bits (234), Expect = 1e-19
Identities = 49/122 (40%), Positives = 72/122 (59%), Gaps = 3/122 (2%)
Query: 8 AVLELLQR-PGNARCADCGAPDPDWASYTLGVFICLSCSGIHRNI-PQVSKVKSVRLDAW 65
+VL+ +Q GN++C DCG PDP WAS LGV +C+ CSGIHR++ SKV+S+ LD+W
Sbjct: 404 SVLQRVQSVAGNSQCGDCGQPDPRWASINLGVLLCIECSGIHRSLGVHCSKVRSLTLDSW 463
Query: 66 EEAQVEFMASHGNDAARARFESKVPSFYYR-PTPSDCQLLREQWIRAKYERQEFIYPEKQ 124
E ++ M GN A +E++ R PT S + +E WI+ KY ++F+
Sbjct: 464 EPELLKLMCELGNSAVNQIYEAQCEGAGSRKPTASSSRQDKEAWIKDKYVEKKFLRKAPM 523
Query: 125 EP 126
P
Sbjct: 524 AP 525
>gi|23943872 small ArfGAP2 [Homo sapiens]
Length = 429
Score = 94.7 bits (234), Expect = 1e-19
Identities = 56/142 (39%), Positives = 82/142 (57%), Gaps = 8/142 (5%)
Query: 4 ERRRAVL-ELLQRPGNARCADCGAPDPDWASYTLGVFICLSCSGIHRNI-PQVSKVKSVR 61
+R +AVL LL N CADC + P WAS+ +GVFIC+ C+GIHRN+ +S+VKSV
Sbjct: 10 DRYQAVLANLLLEEDNKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVN 69
Query: 62 LDAWEEAQVEFMASHGNDAARARFESKVPSFYYRPTPSDCQLLREQWIRAKYERQEFIYP 121
LD W + Q++ M GN A +E+ +P + RP E +IR KYE+++ Y
Sbjct: 70 LDQWTQEQIQCMQEMGNGKANRLYEAYLPETFRRPQIDPAV---EGFIRDKYEKKK--YM 124
Query: 122 EKQEPYSAGYRE-GFLWKRGRD 142
++ +A +E WKRG +
Sbjct: 125 DRSLDINAFRKEKDDKWKRGSE 146
>gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]
Length = 1192
Score = 94.0 bits (232), Expect = 2e-19
Identities = 48/115 (41%), Positives = 66/115 (57%), Gaps = 2/115 (1%)
Query: 8 AVLELLQRPGNARCADCGAPDPDWASYTLGVFICLSCSGIHRNI-PQVSKVKSVRLDAWE 66
A+ + GN+ C DCGAP+P WAS LG IC+ CSGIHRN+ +S+V+S+ LD W
Sbjct: 933 AIQAIRNAKGNSICVDCGAPNPTWASLNLGALICIECSGIHRNLGTHLSRVRSLDLDDWP 992
Query: 67 EAQVEFMASHGNDAARARFESKVPSFYYRPTPSDCQLLREQWIRAKYERQEFIYP 121
+ + GND A +ES +P+ + RE WIRAKYE+ F+ P
Sbjct: 993 RELTLVLTAIGNDTANRVWESDTRG-RAKPSRDSSREERESWIRAKYEQLLFLAP 1046
>gi|7661962 centaurin, gamma 1 isoform PIKE-S [Homo sapiens]
Length = 836
Score = 94.0 bits (232), Expect = 2e-19
Identities = 48/115 (41%), Positives = 66/115 (57%), Gaps = 2/115 (1%)
Query: 8 AVLELLQRPGNARCADCGAPDPDWASYTLGVFICLSCSGIHRNI-PQVSKVKSVRLDAWE 66
A+ + GN+ C DCGAP+P WAS LG IC+ CSGIHRN+ +S+V+S+ LD W
Sbjct: 577 AIQAIRNAKGNSICVDCGAPNPTWASLNLGALICIECSGIHRNLGTHLSRVRSLDLDDWP 636
Query: 67 EAQVEFMASHGNDAARARFESKVPSFYYRPTPSDCQLLREQWIRAKYERQEFIYP 121
+ + GND A +ES +P+ + RE WIRAKYE+ F+ P
Sbjct: 637 RELTLVLTAIGNDTANRVWESDTRG-RAKPSRDSSREERESWIRAKYEQLLFLAP 690
>gi|187608516 centaurin, beta 2 [Homo sapiens]
Length = 778
Score = 91.7 bits (226), Expect = 1e-18
Identities = 46/106 (43%), Positives = 63/106 (59%), Gaps = 3/106 (2%)
Query: 16 PGNARCADCGAPDPDWASYTLGVFICLSCSGIHRNI-PQVSKVKSVRLDAWEEAQVEFMA 74
PGNA C DCG DP WAS LG+ +C+ CSGIHR++ SKV+S+ LD WE ++ M
Sbjct: 409 PGNASCCDCGLADPRWASINLGITLCIECSGIHRSLGVHFSKVRSLTLDTWEPELLKLMC 468
Query: 75 SHGNDAARARFESKVPSF-YYRPTPSDCQLLREQWIRAKYERQEFI 119
GND +E+ V +P P Q +E +IRAKY ++F+
Sbjct: 469 ELGNDVINRVYEANVEKMGIKKPQPGQRQ-EKEAYIRAKYVERKFV 513
>gi|117956373 ArfGAP with GTPase domain, ankyrin repeat and PH
domain 7 [Homo sapiens]
Length = 663
Score = 89.4 bits (220), Expect = 5e-18
Identities = 44/106 (41%), Positives = 65/106 (61%), Gaps = 2/106 (1%)
Query: 17 GNARCADCGAPDPDWASYTLGVFICLSCSGIHRNI-PQVSKVKSVRLDAWEEAQVEFMAS 75
GNA C DC +P WAS LGV +C+ CSGIHR++ ++S+V+S+ LD W + M+S
Sbjct: 452 GNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSS 511
Query: 76 HGNDAARARFESKVPSFYYRPTPSDCQLLREQWIRAKYERQEFIYP 121
GND A + +E +PT + +E+WIR+KYE + F+ P
Sbjct: 512 IGNDLANSIWEGSSQG-RTKPTEKSTREEKERWIRSKYEEKLFLAP 556
>gi|156104893 ArfGAP with GTPase domain, ankyrin repeat and PH
domain 4 [Homo sapiens]
Length = 663
Score = 89.0 bits (219), Expect = 6e-18
Identities = 44/121 (36%), Positives = 71/121 (58%), Gaps = 2/121 (1%)
Query: 2 AKERRRAVLELLQRPGNARCADCGAPDPDWASYTLGVFICLSCSGIHRNI-PQVSKVKSV 60
++ + A+ + GNA C DC +P WAS LGV +C+ CSGIHR++ ++S+V+S+
Sbjct: 437 SQSKAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSL 496
Query: 61 RLDAWEEAQVEFMASHGNDAARARFESKVPSFYYRPTPSDCQLLREQWIRAKYERQEFIY 120
LD W + M+S GND A + +E +P+ + +E+WIR+KYE + F+
Sbjct: 497 ELDDWPVELRKVMSSIGNDLANSIWEGSSQG-QTKPSEKSTREEKERWIRSKYEEKLFLA 555
Query: 121 P 121
P
Sbjct: 556 P 556
>gi|80978934 centaurin, gamma 2 isoform 2 [Homo sapiens]
Length = 804
Score = 88.6 bits (218), Expect = 8e-18
Identities = 42/106 (39%), Positives = 66/106 (62%), Gaps = 2/106 (1%)
Query: 17 GNARCADCGAPDPDWASYTLGVFICLSCSGIHRNI-PQVSKVKSVRLDAWEEAQVEFMAS 75
GN+ C DC +P+WAS LG +C+ CSGIHRN+ +S+V+S+ LD W ++ M+S
Sbjct: 567 GNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPVELIKVMSS 626
Query: 76 HGNDAARARFESKVPSFYYRPTPSDCQLLREQWIRAKYERQEFIYP 121
GN+ A + +E +P+ + +E+WIRAKYE++ F+ P
Sbjct: 627 IGNELANSVWEESSQG-RTKPSVDSTREEKERWIRAKYEQKLFLAP 671
>gi|80978930 centaurin, gamma 2 isoform 1 [Homo sapiens]
Length = 857
Score = 88.6 bits (218), Expect = 8e-18
Identities = 42/106 (39%), Positives = 66/106 (62%), Gaps = 2/106 (1%)
Query: 17 GNARCADCGAPDPDWASYTLGVFICLSCSGIHRNI-PQVSKVKSVRLDAWEEAQVEFMAS 75
GN+ C DC +P+WAS LG +C+ CSGIHRN+ +S+V+S+ LD W ++ M+S
Sbjct: 620 GNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPVELIKVMSS 679
Query: 76 HGNDAARARFESKVPSFYYRPTPSDCQLLREQWIRAKYERQEFIYP 121
GN+ A + +E +P+ + +E+WIRAKYE++ F+ P
Sbjct: 680 IGNELANSVWEESSQG-RTKPSVDSTREEKERWIRAKYEQKLFLAP 724
>gi|166851846 centaurin, gamma-like family, member 3 [Homo sapiens]
Length = 686
Score = 87.4 bits (215), Expect = 2e-17
Identities = 43/106 (40%), Positives = 64/106 (60%), Gaps = 2/106 (1%)
Query: 17 GNARCADCGAPDPDWASYTLGVFICLSCSGIHRNI-PQVSKVKSVRLDAWEEAQVEFMAS 75
GNA C DC +P WAS LGV +C+ CSGIHR++ P +S+V+S+ LD W + M+S
Sbjct: 475 GNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGPHLSRVRSLELDDWPVELRKVMSS 534
Query: 76 HGNDAARARFESKVPSFYYRPTPSDCQLLREQWIRAKYERQEFIYP 121
ND A + +E +P+ + +E+WIR+KYE + F+ P
Sbjct: 535 IVNDLANSIWEGSSQG-QTKPSEKSTREEKERWIRSKYEEKLFLAP 579
>gi|206597513 ArfGAP with RhoGAP domain, ankyrin repeat and PH
domain 1 isoform a [Homo sapiens]
Length = 1205
Score = 87.0 bits (214), Expect = 2e-17
Identities = 91/346 (26%), Positives = 135/346 (39%), Gaps = 43/346 (12%)
Query: 18 NARCADCGAPDPDWASYTLGVFICLSCSGIHRNI-PQVSKVKSVRLD--AWEEAQVEFMA 74
N CADCGAP PDWAS L V IC C+G HR + VSKV+S+++D W E +E
Sbjct: 302 NRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELFL 361
Query: 75 SHGNDAARARFESKVPSFYYRPTPSDCQLLREQWIRAKYERQEFIYPEKQEPYSAGYREG 134
GN A + + VP PS R + AKY ++ + P E
Sbjct: 362 QLGNGAGNRFWAANVPP-SEALQPSSSPSTRRCHLEAKYREGKY---RRYHPLFGNQEEL 417
Query: 135 FLWKRGRDNGQFLSRKFVLTEREGALKYFNRNDAKEPKAVMKIEHLNATFQPAKIGHPHG 194
L+ L + F+ D + P + E T
Sbjct: 418 DKALCAAVTTTDLAETQALLGCGAGINCFS-GDPEAPTPLALAEQAGQT----------- 465
Query: 195 LQVTYLKDNSTRNIFIYHEDGKEIVDWFNALRAARFHYLQVAFPGASDADLVPKLSRNYL 254
LQ+ +L++N T V ++++ HY V P S + + K +
Sbjct: 466 LQMEFLRNNRTTE-----------VPRLDSMKPLEKHY-SVVLPTVSHSGFLYKTA---- 509
Query: 255 KEGYMEKTGPKQTEGFRKRWFTMDDRRLMYFKDPLDAFARGEVFIGSKESGYTVLHGFPP 314
G + + + E F +RW + D L YF++ GE+ + S L PP
Sbjct: 510 SAGKLLQ-DRRAREEFSRRWCVLGDGVLSYFENERAVTPNGEI----RASEIVCLAVPPP 564
Query: 315 STQGHHWPHGITIVTP-DRKFLFACETESDQREWVAAFQKAVDRPM 359
T H + H + T +R +LF E+ EWV KA P+
Sbjct: 565 DT--HGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPL 608
Score = 46.2 bits (108), Expect = 5e-05
Identities = 26/102 (25%), Positives = 50/102 (49%), Gaps = 12/102 (11%)
Query: 254 LKEGYMEKTGPKQTEGFRKRWFTMDDRRLMYFKDPLDAFARGEVFIGSKESGYTVLHGFP 313
+K G+++K P+ + ++KRW +D L YF DA+++ FI + G
Sbjct: 84 IKAGWLDKNPPQGSYIYQKRWVRLDTDHLRYFDSNKDAYSKR--FISVACISHVAAIG-- 139
Query: 314 PSTQGHHWPHGITIVTPDRKFLFACETESDQREWVAAFQKAV 355
++T +R F F E++ +++EW+ A Q+A+
Sbjct: 140 --------DQKFEVITNNRTFAFRAESDVERKEWMQALQQAM 173
Score = 29.3 bits (64), Expect = 6.0
Identities = 12/39 (30%), Positives = 22/39 (56%)
Query: 327 IVTPDRKFLFACETESDQREWVAAFQKAVDRPMLPQEYA 365
+ TP R F F+ ++E ++ +W+ A Q A+ + E A
Sbjct: 255 LTTPYRIFSFSADSELEKEQWLEAMQGAIAEALSTSEVA 293
>gi|92091600 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain
1 isoform c [Homo sapiens]
Length = 1450
Score = 87.0 bits (214), Expect = 2e-17
Identities = 91/346 (26%), Positives = 135/346 (39%), Gaps = 43/346 (12%)
Query: 18 NARCADCGAPDPDWASYTLGVFICLSCSGIHRNI-PQVSKVKSVRLD--AWEEAQVEFMA 74
N CADCGAP PDWAS L V IC C+G HR + VSKV+S+++D W E +E
Sbjct: 547 NRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTETLIELFL 606
Query: 75 SHGNDAARARFESKVPSFYYRPTPSDCQLLREQWIRAKYERQEFIYPEKQEPYSAGYREG 134
GN A + + VP PS R + AKY ++ + P E
Sbjct: 607 QLGNGAGNRFWAANVPP-SEALQPSSSPSTRRCHLEAKYREGKY---RRYHPLFGNQEEL 662
Query: 135 FLWKRGRDNGQFLSRKFVLTEREGALKYFNRNDAKEPKAVMKIEHLNATFQPAKIGHPHG 194
L+ L + F+ D + P + E T
Sbjct: 663 DKALCAAVTTTDLAETQALLGCGAGINCFS-GDPEAPTPLALAEQAGQT----------- 710
Query: 195 LQVTYLKDNSTRNIFIYHEDGKEIVDWFNALRAARFHYLQVAFPGASDADLVPKLSRNYL 254
LQ+ +L++N T V ++++ HY V P S + + K +
Sbjct: 711 LQMEFLRNNRTTE-----------VPRLDSMKPLEKHY-SVVLPTVSHSGFLYKTA---- 754
Query: 255 KEGYMEKTGPKQTEGFRKRWFTMDDRRLMYFKDPLDAFARGEVFIGSKESGYTVLHGFPP 314
G + + + E F +RW + D L YF++ GE+ + S L PP
Sbjct: 755 SAGKLLQ-DRRAREEFSRRWCVLGDGVLSYFENERAVTPNGEI----RASEIVCLAVPPP 809
Query: 315 STQGHHWPHGITIVTP-DRKFLFACETESDQREWVAAFQKAVDRPM 359
T H + H + T +R +LF E+ EWV KA P+
Sbjct: 810 DT--HGFEHTFEVYTEGERLYLFGLESAEQAHEWVKCIAKAFVPPL 853
Score = 46.2 bits (108), Expect = 5e-05
Identities = 26/102 (25%), Positives = 50/102 (49%), Gaps = 12/102 (11%)
Query: 254 LKEGYMEKTGPKQTEGFRKRWFTMDDRRLMYFKDPLDAFARGEVFIGSKESGYTVLHGFP 313
+K G+++K P+ + ++KRW +D L YF DA+++ FI + G
Sbjct: 329 IKAGWLDKNPPQGSYIYQKRWVRLDTDHLRYFDSNKDAYSKR--FISVACISHVAAIG-- 384
Query: 314 PSTQGHHWPHGITIVTPDRKFLFACETESDQREWVAAFQKAV 355
++T +R F F E++ +++EW+ A Q+A+
Sbjct: 385 --------DQKFEVITNNRTFAFRAESDVERKEWMQALQQAM 418
Score = 29.3 bits (64), Expect = 6.0
Identities = 12/39 (30%), Positives = 22/39 (56%)
Query: 327 IVTPDRKFLFACETESDQREWVAAFQKAVDRPMLPQEYA 365
+ TP R F F+ ++E ++ +W+ A Q A+ + E A
Sbjct: 500 LTTPYRIFSFSADSELEKEQWLEAMQGAIAEALSTSEVA 538
>gi|117956371 ArfGAP with GTPase domain, ankyrin repeat and PH
domain 8 [Homo sapiens]
Length = 663
Score = 86.7 bits (213), Expect = 3e-17
Identities = 46/122 (37%), Positives = 69/122 (56%), Gaps = 4/122 (3%)
Query: 17 GNARCADCGAPDPDWASYTLGVFICLSCSGIHRNI-PQVSKVKSVRLDAWEEAQVEFMAS 75
GNA C DC +P WAS LGV +C+ CSGIH ++ ++S+V+S+ LD W + M+S
Sbjct: 452 GNAHCVDCETQNPKWASLNLGVLMCIECSGIHHSLGTRLSRVRSLELDDWPVELRKVMSS 511
Query: 76 HGNDAARARFESKVPSFYYRPTPSDCQLLREQWIRAKYERQEFIYPEKQEPYSAGYREGF 135
GND A + +E +P+ + +E+WIR+KYE + F+ P S G +
Sbjct: 512 IGNDLANSIWEGSSQG-QTKPSEKSTREEKERWIRSKYEEKLFLAPLPCTELSLG--QQL 568
Query: 136 LW 137
LW
Sbjct: 569 LW 570
>gi|148806877 ankyrin repeat and GTPase domain Arf GTPase activating
protein 11 [Homo sapiens]
Length = 550
Score = 86.3 bits (212), Expect = 4e-17
Identities = 42/106 (39%), Positives = 65/106 (61%), Gaps = 2/106 (1%)
Query: 17 GNARCADCGAPDPDWASYTLGVFICLSCSGIHRNI-PQVSKVKSVRLDAWEEAQVEFMAS 75
GN+ C DC +P WAS LGV +C+ CSGIHR++ ++S+V+S+ LD W + M+S
Sbjct: 339 GNSHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSS 398
Query: 76 HGNDAARARFESKVPSFYYRPTPSDCQLLREQWIRAKYERQEFIYP 121
GND A + +E +P+ + +E+WIR+KYE + F+ P
Sbjct: 399 IGNDLANSIWEGSSQG-QTKPSIESTREEKERWIRSKYEHKLFLAP 443
>gi|46094081 development and differentiation enhancing factor 1
[Homo sapiens]
Length = 1129
Score = 85.1 bits (209), Expect = 9e-17
Identities = 42/114 (36%), Positives = 69/114 (60%), Gaps = 2/114 (1%)
Query: 7 RAVLELLQR-PGNARCADCGAPDPDWASYTLGVFICLSCSGIHRNI-PQVSKVKSVRLDA 64
+A++E +QR PGN C DCG+ +P W S LG+ C+ CSGIHR + +S+++S+ LD
Sbjct: 439 KAIIEDVQRLPGNDICCDCGSSEPTWLSTNLGILTCIECSGIHREMGVHISRIQSLELDK 498
Query: 65 WEEAQVEFMASHGNDAARARFESKVPSFYYRPTPSDCQLLREQWIRAKYERQEF 118
+++ + GN++ E+ +PS +PTPS +R+++I AKY F
Sbjct: 499 LGTSELLLAKNVGNNSFNDIMEANLPSPSPKPTPSSDMTVRKEYITAKYVDHRF 552
Score = 35.0 bits (79), Expect = 0.11
Identities = 30/133 (22%), Positives = 54/133 (40%), Gaps = 17/133 (12%)
Query: 124 QEPYSAGYREGFLWKRGRDNGQFLSRK--FVLTEREGALKYFNRNDAKEPKAVMKIEHLN 181
Q+ S + G+ + + N ++ S K ++L + +G K + R ++ I H
Sbjct: 301 QKEDSQSRQGGYSMHQLQGNKEYGSEKKGYLLKKSDGIRKVWQRRKCSVKNGILTISHAT 360
Query: 182 ATFQPAKIGHPHGLQVTYLKDNS-----------TRNIFIYHEDGKEIVDWFNALRAARF 230
+ QPAK+ L +K N+ R ED ++ V W + L ++
Sbjct: 361 SNRQPAKL----NLLTCQVKPNAEDKKSFDLISHNRTYHFQAEDEQDYVAWISVLTNSKE 416
Query: 231 HYLQVAFPGASDA 243
L +AF G A
Sbjct: 417 EALTMAFRGEQSA 429
>gi|239744074 PREDICTED: ArfGAP with GTPase domain, ankyrin repeat
and PH domain 9 [Homo sapiens]
Length = 684
Score = 84.0 bits (206), Expect = 2e-16
Identities = 42/106 (39%), Positives = 63/106 (59%), Gaps = 2/106 (1%)
Query: 17 GNARCADCGAPDPDWASYTLGVFICLSCSGIHRNI-PQVSKVKSVRLDAWEEAQVEFMAS 75
GNA C DC +P WAS LGV +C+ CSGIHR+ ++S+V+S+ LD W + M+S
Sbjct: 475 GNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRKVMSS 534
Query: 76 HGNDAARARFESKVPSFYYRPTPSDCQLLREQWIRAKYERQEFIYP 121
GN+ A + +E +P+ + +E WIR+KYE + F+ P
Sbjct: 535 IGNELANSIWEGSSQG-QTKPSIKSTREEKEWWIRSKYEEKLFLAP 579
>gi|239744064 PREDICTED: ArfGAP with GTPase domain, ankyrin repeat
and PH domain 10 [Homo sapiens]
Length = 684
Score = 84.0 bits (206), Expect = 2e-16
Identities = 42/106 (39%), Positives = 63/106 (59%), Gaps = 2/106 (1%)
Query: 17 GNARCADCGAPDPDWASYTLGVFICLSCSGIHRNI-PQVSKVKSVRLDAWEEAQVEFMAS 75
GNA C DC +P WAS LGV +C+ CSGIHR+ ++S+V+S+ LD W + M+S
Sbjct: 475 GNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRKVMSS 534
Query: 76 HGNDAARARFESKVPSFYYRPTPSDCQLLREQWIRAKYERQEFIYP 121
GN+ A + +E +P+ + +E WIR+KYE + F+ P
Sbjct: 535 IGNELANSIWEGSSQG-QTKPSIKSTREEKEWWIRSKYEEKLFLAP 579
>gi|221136914 ArfGAP with GTPase domain, ankyrin repeat and PH
domain 5 [Homo sapiens]
Length = 686
Score = 83.6 bits (205), Expect = 3e-16
Identities = 42/106 (39%), Positives = 64/106 (60%), Gaps = 2/106 (1%)
Query: 17 GNARCADCGAPDPDWASYTLGVFICLSCSGIHRNI-PQVSKVKSVRLDAWEEAQVEFMAS 75
GNA C D +P WAS LGV +C+ CSGIHR++ ++S+V+S+ LD W + M+S
Sbjct: 475 GNAHCVDYETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSS 534
Query: 76 HGNDAARARFESKVPSFYYRPTPSDCQLLREQWIRAKYERQEFIYP 121
GND A + +E +P+ + +E+WIR+KYE + F+ P
Sbjct: 535 IGNDLANSIWEGSSQG-QTKPSVKSTREEKERWIRSKYEEKLFLAP 579
>gi|221307473 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
isoform b [Homo sapiens]
Length = 894
Score = 78.6 bits (192), Expect = 9e-15
Identities = 48/147 (32%), Positives = 75/147 (51%), Gaps = 10/147 (6%)
Query: 9 VLELLQRPGNARCADCGAPDPDWASYTLGVFICLSCSGIHRNI-PQVSKVKSVRLDAWEE 67
+ E+ RPGN++C DCGA DP W S LGV C+ CSG+HR + + S+++S+ LD
Sbjct: 420 IAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGP 479
Query: 68 AQVEFMASHGNDAARARFESKVPSF-YYRPTPSDCQLLREQWIRAKYERQEF---IYPEK 123
+++ + GN + E+++PS +P+ R +I AKY F PE
Sbjct: 480 SELLLALNMGNTSFNEVMEAQLPSHGGPKPSAESDMGTRRDYIMAKYVEHRFARRCTPEP 539
Query: 124 QEPYSAGYREGFL-----WKRGRDNGQ 145
Q ++A L + G+D GQ
Sbjct: 540 QRLWTAICNRDLLSVLEAFANGQDFGQ 566
>gi|19923540 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
isoform a [Homo sapiens]
Length = 903
Score = 78.6 bits (192), Expect = 9e-15
Identities = 48/147 (32%), Positives = 75/147 (51%), Gaps = 10/147 (6%)
Query: 9 VLELLQRPGNARCADCGAPDPDWASYTLGVFICLSCSGIHRNI-PQVSKVKSVRLDAWEE 67
+ E+ RPGN++C DCGA DP W S LGV C+ CSG+HR + + S+++S+ LD
Sbjct: 429 IAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGP 488
Query: 68 AQVEFMASHGNDAARARFESKVPSF-YYRPTPSDCQLLREQWIRAKYERQEF---IYPEK 123
+++ + GN + E+++PS +P+ R +I AKY F PE
Sbjct: 489 SELLLALNMGNTSFNEVMEAQLPSHGGPKPSAESDMGTRRDYIMAKYVEHRFARRCTPEP 548
Query: 124 QEPYSAGYREGFL-----WKRGRDNGQ 145
Q ++A L + G+D GQ
Sbjct: 549 QRLWTAICNRDLLSVLEAFANGQDFGQ 575
>gi|206597522 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
isoform b [Homo sapiens]
Length = 961
Score = 70.1 bits (170), Expect = 3e-12
Identities = 37/115 (32%), Positives = 59/115 (51%), Gaps = 2/115 (1%)
Query: 6 RRAVLELLQRPGNARCADCGAPDPDWASYTLGVFICLSCSGIHRNI-PQVSKVKSVRLDA 64
+ + E+ + GN C DCGAPDP W S LG+ C+ CSGIHR + S+++S+ LD
Sbjct: 421 KEIISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVHYSRMQSLTLDV 480
Query: 65 WEEAQVEFMASHGNDAARARFESKVPS-FYYRPTPSDCQLLREQWIRAKYERQEF 118
+++ + GN E +P+ +P P R+ +I AKY + +
Sbjct: 481 LGTSELLLAKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYITAKYIERRY 535
>gi|4502249 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
isoform a [Homo sapiens]
Length = 1006
Score = 70.1 bits (170), Expect = 3e-12
Identities = 37/115 (32%), Positives = 59/115 (51%), Gaps = 2/115 (1%)
Query: 6 RRAVLELLQRPGNARCADCGAPDPDWASYTLGVFICLSCSGIHRNI-PQVSKVKSVRLDA 64
+ + E+ + GN C DCGAPDP W S LG+ C+ CSGIHR + S+++S+ LD
Sbjct: 421 KEIISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVHYSRMQSLTLDV 480
Query: 65 WEEAQVEFMASHGNDAARARFESKVPS-FYYRPTPSDCQLLREQWIRAKYERQEF 118
+++ + GN E +P+ +P P R+ +I AKY + +
Sbjct: 481 LGTSELLLAKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYITAKYIERRY 535
>gi|28416436 ADP-ribosylation factor GTPase activating protein 1
isoform b [Homo sapiens]
Length = 414
Score = 69.3 bits (168), Expect = 5e-12
Identities = 38/90 (42%), Positives = 54/90 (60%), Gaps = 2/90 (2%)
Query: 1 MAKERRRAVL-ELLQRPGNARCADCGAPDPDWASYTLGVFICLSCSGIHRNI-PQVSKVK 58
MA R R VL E+ + N C +CGA +P W S T G++ICL CSG HR + +S V+
Sbjct: 1 MASPRTRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVR 60
Query: 59 SVRLDAWEEAQVEFMASHGNDAARARFESK 88
SV +D W++ ++E M + GN R ES+
Sbjct: 61 SVTMDKWKDIELEKMKAGGNAKFREFLESQ 90
>gi|8922652 ADP-ribosylation factor GTPase activating protein 1
isoform a [Homo sapiens]
Length = 406
Score = 69.3 bits (168), Expect = 5e-12
Identities = 38/90 (42%), Positives = 54/90 (60%), Gaps = 2/90 (2%)
Query: 1 MAKERRRAVL-ELLQRPGNARCADCGAPDPDWASYTLGVFICLSCSGIHRNI-PQVSKVK 58
MA R R VL E+ + N C +CGA +P W S T G++ICL CSG HR + +S V+
Sbjct: 1 MASPRTRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVR 60
Query: 59 SVRLDAWEEAQVEFMASHGNDAARARFESK 88
SV +D W++ ++E M + GN R ES+
Sbjct: 61 SVTMDKWKDIELEKMKAGGNAKFREFLESQ 90
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.433
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,610,735
Number of Sequences: 37866
Number of extensions: 708900
Number of successful extensions: 1690
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 64
Number of HSP's successfully gapped in prelim test: 44
Number of HSP's that attempted gapping in prelim test: 1508
Number of HSP's gapped (non-prelim): 174
length of query: 374
length of database: 18,247,518
effective HSP length: 104
effective length of query: 270
effective length of database: 14,309,454
effective search space: 3863552580
effective search space used: 3863552580
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.