Search of human proteins with 67906814

Search of human proteins with 67906814

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|67906814 Rho GTPase activating protein 19 [Homo sapiens]
         (494 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|67906814 Rho GTPase activating protein 19 [Homo sapiens]           983   0.0  
gi|39932589 Rho GTPase activating protein 18 [Homo sapiens]            90   4e-18
gi|239757488 PREDICTED: chromosome 20 open reading frame 95 [Hom...    87   3e-17
gi|239752003 PREDICTED: chromosome 20 open reading frame 95 [Hom...    87   3e-17
gi|239746488 PREDICTED: Rho GTPase-activating protein 18-like [H...    87   3e-17
gi|188497642 ARHGAP15 [Homo sapiens]                                   84   2e-16
gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo sa...    83   7e-16
gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo sa...    83   7e-16
gi|91208437 GEM interacting protein [Homo sapiens]                     82   1e-15
gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo sa...    82   1e-15
gi|134304853 PTPL1-associated RhoGAP 1 [Homo sapiens]                  81   2e-15
gi|7382480 Rho GTPase activating protein 6 isoform 4 [Homo sapiens]    80   4e-15
gi|95091988 Rho GTPase activating protein 6 isoform 3 [Homo sapi...    80   4e-15
gi|95091875 Rho GTPase activating protein 6 isoform 1 [Homo sapi...    80   4e-15
gi|4757766 Rho GTPase activating protein 1 [Homo sapiens]              79   9e-15
gi|26986534 Rho GTPase activating protein 12 [Homo sapiens]            79   9e-15
gi|34013590 Rho GTPase activating protein 2 [Homo sapiens]             77   4e-14
gi|33188433 deleted in liver cancer 1 isoform 1 [Homo sapiens]         77   5e-14
gi|33188437 deleted in liver cancer 1 isoform 2 [Homo sapiens]         77   5e-14
gi|194272142 myosin IXB isoform 2 [Homo sapiens]                       75   2e-13
gi|33356170 myosin IXB isoform 1 [Homo sapiens]                        75   2e-13
gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens]        74   3e-13
gi|41281907 StAR-related lipid transfer (START) domain containin...    73   5e-13
gi|16445031 StAR-related lipid transfer (START) domain containin...    73   5e-13
gi|41281898 StAR-related lipid transfer (START) domain containin...    73   5e-13
gi|226693398 Rho GTPase activating protein 27 isoform b [Homo sa...    72   9e-13
gi|40548322 Rho GTPase activating protein 27 isoform a [Homo sap...    72   9e-13
gi|206597515 ArfGAP with RhoGAP domain, ankyrin repeat and PH do...    72   9e-13
gi|206597513 ArfGAP with RhoGAP domain, ankyrin repeat and PH do...    72   9e-13
gi|92091600 ArfGAP with RhoGAP domain, ankyrin repeat and PH dom...    72   9e-13

>gi|67906814 Rho GTPase activating protein 19 [Homo sapiens]
          Length = 494

 Score =  983 bits (2540), Expect = 0.0
 Identities = 494/494 (100%), Positives = 494/494 (100%)

Query: 1   MATEAQSEGEVPARESGRSDAICSFVICNDSSLRGQPIIFNPDFFVEKLRHEKPEIFTEL 60
           MATEAQSEGEVPARESGRSDAICSFVICNDSSLRGQPIIFNPDFFVEKLRHEKPEIFTEL
Sbjct: 1   MATEAQSEGEVPARESGRSDAICSFVICNDSSLRGQPIIFNPDFFVEKLRHEKPEIFTEL 60

Query: 61  VVSNITRLIDLPGTELAQLMGEVDLKLPGGAGPASGFFRSLMSLKRKEKGVIFGSPLTEE 120
           VVSNITRLIDLPGTELAQLMGEVDLKLPGGAGPASGFFRSLMSLKRKEKGVIFGSPLTEE
Sbjct: 61  VVSNITRLIDLPGTELAQLMGEVDLKLPGGAGPASGFFRSLMSLKRKEKGVIFGSPLTEE 120

Query: 121 GIAQIYQLIEYLHKNLRVEGLFRVPGNSVRQQILRDALNNGTDIDLESGEFHSNDVATLL 180
           GIAQIYQLIEYLHKNLRVEGLFRVPGNSVRQQILRDALNNGTDIDLESGEFHSNDVATLL
Sbjct: 121 GIAQIYQLIEYLHKNLRVEGLFRVPGNSVRQQILRDALNNGTDIDLESGEFHSNDVATLL 180

Query: 181 KMFLGELPEPLLTHKHFNAHLKIADLMQFDDKGNKTNIPDKDRQIEALQLLFLILPPPNR 240
           KMFLGELPEPLLTHKHFNAHLKIADLMQFDDKGNKTNIPDKDRQIEALQLLFLILPPPNR
Sbjct: 181 KMFLGELPEPLLTHKHFNAHLKIADLMQFDDKGNKTNIPDKDRQIEALQLLFLILPPPNR 240

Query: 241 NLLKLLLDLLYQTAKKQDKNKMSAYNLALMFAPHVLWPKNVTANDLQENITKLNSGMAFM 300
           NLLKLLLDLLYQTAKKQDKNKMSAYNLALMFAPHVLWPKNVTANDLQENITKLNSGMAFM
Sbjct: 241 NLLKLLLDLLYQTAKKQDKNKMSAYNLALMFAPHVLWPKNVTANDLQENITKLNSGMAFM 300

Query: 301 IKHSQKLFKAPAYIRECARLHYLGSRTQASKDDLDLIASCHTKSFQLAKSQKRNRVDSCP 360
           IKHSQKLFKAPAYIRECARLHYLGSRTQASKDDLDLIASCHTKSFQLAKSQKRNRVDSCP
Sbjct: 301 IKHSQKLFKAPAYIRECARLHYLGSRTQASKDDLDLIASCHTKSFQLAKSQKRNRVDSCP 360

Query: 361 HQEETQHHTEEALRELFQHVHDMPESAKKKQLIRQFNKQSLTQTPGREPSTSQVQKRARS 420
           HQEETQHHTEEALRELFQHVHDMPESAKKKQLIRQFNKQSLTQTPGREPSTSQVQKRARS
Sbjct: 361 HQEETQHHTEEALRELFQHVHDMPESAKKKQLIRQFNKQSLTQTPGREPSTSQVQKRARS 420

Query: 421 RSFSGLIKRKVLGNQMMSEKKKKNPTPESVAIGELKGTSKENRNLLFSGSPAVTMTPTRL 480
           RSFSGLIKRKVLGNQMMSEKKKKNPTPESVAIGELKGTSKENRNLLFSGSPAVTMTPTRL
Sbjct: 421 RSFSGLIKRKVLGNQMMSEKKKKNPTPESVAIGELKGTSKENRNLLFSGSPAVTMTPTRL 480

Query: 481 KWSEGKKEGKKGFL 494
           KWSEGKKEGKKGFL
Sbjct: 481 KWSEGKKEGKKGFL 494


>gi|39932589 Rho GTPase activating protein 18 [Homo sapiens]
          Length = 663

 Score = 90.1 bits (222), Expect = 4e-18
 Identities = 60/189 (31%), Positives = 102/189 (53%), Gaps = 23/189 (12%)

Query: 134 KNLRVEGLFRVPGNSVRQQILRDALN----NGTDIDLESGEFHSNDVATLLKMFLGELPE 189
           + L  EGL R+PG ++R + L   L      GT  + ES + H  D A+LLK+F+ ELP+
Sbjct: 356 RGLETEGLLRIPGAAIRIKNLCQELEAKFYEGT-FNWESVKQH--DAASLLKLFIRELPQ 412

Query: 190 PLLTHKHFNAHLKIADLMQFDDKGNKTNIPDKDRQIEALQLLFLILPPPNRNLLKLLLDL 249
           PLL+ ++  A   +             N+P K +Q++AL LL ++LP  NR+ LK LL+ 
Sbjct: 413 PLLSVEYLKAFQAVQ------------NLPTKKQQLQALNLLVILLPDANRDTLKALLEF 460

Query: 250 LYQTAKKQDKNKMSAYNLALMFAPHVLWPKNVTANDLQENITKLNSG----MAFMIKHSQ 305
           L +    ++KNKM+  N+A++ AP++     +     ++    + +G    M  +IK+ +
Sbjct: 461 LQRVIDNKEKNKMTVMNVAMVMAPNLFMCHALGLKSSEQREFVMAAGTANTMHLLIKYQK 520

Query: 306 KLFKAPAYI 314
            L+  P +I
Sbjct: 521 LLWTIPKFI 529


>gi|239757488 PREDICTED: chromosome 20 open reading frame 95 [Homo
           sapiens]
          Length = 622

 Score = 87.0 bits (214), Expect = 3e-17
 Identities = 52/143 (36%), Positives = 78/143 (54%), Gaps = 13/143 (9%)

Query: 134 KNLRVEGLFRVPGNSVRQQILRDALNNGTDIDLES-GEFHSNDVATLLKMFLGELPEPLL 192
           + L +EG+ RVPG+  R + L   L       L S  E H ND + LLK F+ +LP PLL
Sbjct: 302 RGLDMEGILRVPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDASDLLKRFIRKLPTPLL 361

Query: 193 THKHFNAHLKIADLMQFDDKGNKTNIPDKDRQIEALQLLFLILPPPNRNLLKLLLDLLYQ 252
           T ++  A   +             NIP+  ++++ L LL LILP PNRN LK LL+ L +
Sbjct: 362 TAEYLPAFAVVP------------NIPNLKQRLQVLHLLILILPEPNRNALKALLEFLRK 409

Query: 253 TAKKQDKNKMSAYNLALMFAPHV 275
              ++  NKM+  N++ + AP++
Sbjct: 410 VVAREQHNKMTLRNVSTVMAPNL 432


>gi|239752003 PREDICTED: chromosome 20 open reading frame 95 [Homo
           sapiens]
          Length = 622

 Score = 87.0 bits (214), Expect = 3e-17
 Identities = 52/143 (36%), Positives = 78/143 (54%), Gaps = 13/143 (9%)

Query: 134 KNLRVEGLFRVPGNSVRQQILRDALNNGTDIDLES-GEFHSNDVATLLKMFLGELPEPLL 192
           + L +EG+ RVPG+  R + L   L       L S  E H ND + LLK F+ +LP PLL
Sbjct: 302 RGLDMEGILRVPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDASDLLKRFIRKLPTPLL 361

Query: 193 THKHFNAHLKIADLMQFDDKGNKTNIPDKDRQIEALQLLFLILPPPNRNLLKLLLDLLYQ 252
           T ++  A   +             NIP+  ++++ L LL LILP PNRN LK LL+ L +
Sbjct: 362 TAEYLPAFAVVP------------NIPNLKQRLQVLHLLILILPEPNRNALKALLEFLRK 409

Query: 253 TAKKQDKNKMSAYNLALMFAPHV 275
              ++  NKM+  N++ + AP++
Sbjct: 410 VVAREQHNKMTLRNVSTVMAPNL 432


>gi|239746488 PREDICTED: Rho GTPase-activating protein 18-like [Homo
           sapiens]
          Length = 622

 Score = 87.0 bits (214), Expect = 3e-17
 Identities = 52/143 (36%), Positives = 78/143 (54%), Gaps = 13/143 (9%)

Query: 134 KNLRVEGLFRVPGNSVRQQILRDALNNGTDIDLES-GEFHSNDVATLLKMFLGELPEPLL 192
           + L +EG+ RVPG+  R + L   L       L S  E H ND + LLK F+ +LP PLL
Sbjct: 302 RGLDMEGILRVPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDASDLLKRFIRKLPTPLL 361

Query: 193 THKHFNAHLKIADLMQFDDKGNKTNIPDKDRQIEALQLLFLILPPPNRNLLKLLLDLLYQ 252
           T ++  A   +             NIP+  ++++ L LL LILP PNRN LK LL+ L +
Sbjct: 362 TAEYLPAFAVVP------------NIPNLKQRLQVLHLLILILPEPNRNALKALLEFLRK 409

Query: 253 TAKKQDKNKMSAYNLALMFAPHV 275
              ++  NKM+  N++ + AP++
Sbjct: 410 VVAREQHNKMTLRNVSTVMAPNL 432


>gi|188497642 ARHGAP15 [Homo sapiens]
          Length = 475

 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 72/220 (32%), Positives = 107/220 (48%), Gaps = 24/220 (10%)

Query: 100 SLMSLKRKE--KGVIFGSPLTEEGIAQ-------IYQLIEYLHKN-LRVEGLFRVPGNSV 149
           SL +L+ K   K  IFGS L +    +       + Q IE + K  L V+G++RV GN  
Sbjct: 264 SLKTLQEKGLIKDQIFGSHLHKVCERENSTVPWFVKQCIEAVEKRGLDVDGIYRVSGNLA 323

Query: 150 RQQILRDALNNGTDIDLESGEFHSNDVAT-LLKMFLGELPEPLLTHKHFNAHLKIADLMQ 208
             Q LR  +N    ++L+  ++    V T  LKMF  ELPEPL  +  F          Q
Sbjct: 324 TIQKLRFIVNQEEKLNLDDSQWEDIHVVTGALKMFFRELPEPLFPYSFFE---------Q 374

Query: 209 FDDKGNKTNIPDKDRQIEALQLLFLILPPPNRNLLKLLLDLLYQTAKKQDKNKMSAYNLA 268
           F +   K    D + +IEA++ L   LPPPNR+ +K+L   L +   K  KN MS  +L 
Sbjct: 375 FVEAIKKQ---DNNTRIEAVKSLVQKLPPPNRDTMKVLFGHLTKIVAKASKNLMSTQSLG 431

Query: 269 LMFAPHVLWPKNVTANDLQENITKLNSGMAFMIKHSQKLF 308
           ++F P +L  +N T N +  ++   N     M+    K+F
Sbjct: 432 IVFGPTLLRAENETGN-MAIHMVYQNQIAELMLSEYSKIF 470


>gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo
           sapiens]
          Length = 653

 Score = 82.8 bits (203), Expect = 7e-16
 Identities = 69/227 (30%), Positives = 108/227 (47%), Gaps = 19/227 (8%)

Query: 92  GPASG--FFRSLMSLKRKEKGVIFGSPLTEEGIAQIYQLIEYLHKNLRVEGLFRVPGNSV 149
           GP  G  F + L    R EK   +G+ L    + Q    I    + L+ EGLFR+PG + 
Sbjct: 31  GPFGGGIFGQKLEDTVRYEKR--YGNRLAPMLVEQCVDFIR--QRGLKEEGLFRLPGQAN 86

Query: 150 RQQILRDALNNGTDIDLESG-EFHSNDVATLLKMFLGELPEPLLTHKHFNAHLKIADLMQ 208
             + L+DA + G     +S  + H+  VA+LLK++L ELPEP++ +  +   L  A L+ 
Sbjct: 87  LVKELQDAFDCGEKPSFDSNTDVHT--VASLLKLYLRELPEPVIPYAKYEDFLSCAKLLS 144

Query: 209 FDDKGNKTNIPDKDRQIEALQLLFLILPPPNRNLLKLLLDLLYQTAKKQDKNKMSAYNLA 268
              K  +  + +  +Q+++L       P  N NLLK +   L +       NKMS  NLA
Sbjct: 145 ---KEEEAGVKELAKQVKSL-------PVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLA 194

Query: 269 LMFAPHVLWPKNVTANDLQENITKLNSGMAFMIKHSQKLFKAPAYIR 315
            +F P++L PK      + E    +   M+ MI     LF   A ++
Sbjct: 195 TVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMISKHDCLFPKDAELQ 241


>gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo
           sapiens]
          Length = 748

 Score = 82.8 bits (203), Expect = 7e-16
 Identities = 69/227 (30%), Positives = 108/227 (47%), Gaps = 19/227 (8%)

Query: 92  GPASG--FFRSLMSLKRKEKGVIFGSPLTEEGIAQIYQLIEYLHKNLRVEGLFRVPGNSV 149
           GP  G  F + L    R EK   +G+ L    + Q    I    + L+ EGLFR+PG + 
Sbjct: 126 GPFGGGIFGQKLEDTVRYEKR--YGNRLAPMLVEQCVDFIR--QRGLKEEGLFRLPGQAN 181

Query: 150 RQQILRDALNNGTDIDLESG-EFHSNDVATLLKMFLGELPEPLLTHKHFNAHLKIADLMQ 208
             + L+DA + G     +S  + H+  VA+LLK++L ELPEP++ +  +   L  A L+ 
Sbjct: 182 LVKELQDAFDCGEKPSFDSNTDVHT--VASLLKLYLRELPEPVIPYAKYEDFLSCAKLLS 239

Query: 209 FDDKGNKTNIPDKDRQIEALQLLFLILPPPNRNLLKLLLDLLYQTAKKQDKNKMSAYNLA 268
              K  +  + +  +Q+++L       P  N NLLK +   L +       NKMS  NLA
Sbjct: 240 ---KEEEAGVKELAKQVKSL-------PVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLA 289

Query: 269 LMFAPHVLWPKNVTANDLQENITKLNSGMAFMIKHSQKLFKAPAYIR 315
            +F P++L PK      + E    +   M+ MI     LF   A ++
Sbjct: 290 TVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMISKHDCLFPKDAELQ 336


>gi|91208437 GEM interacting protein [Homo sapiens]
          Length = 970

 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 59/185 (31%), Positives = 98/185 (52%), Gaps = 7/185 (3%)

Query: 130 EYLHKNLRVEGLFRVPGNSVRQQILRDALNNGTDIDLESGEFHSNDVATLLKMFLGELPE 189
           E  H+ L V+G++RV G+ VR + L  A  NG  +   SG    +DV+++LK FL EL E
Sbjct: 574 EIEHRALDVQGIYRVSGSRVRVERLCQAFENGRALVELSGN-SPHDVSSVLKRFLQELTE 632

Query: 190 PLLTHKHFNAHLKIADLMQFDDKGNKTNIPDKDRQIEALQLLFLILPPPNRNLLKLLLDL 249
           P++    ++A + +A  +  D   +          I +L+ L + LP  N N L+ L+  
Sbjct: 633 PVIPFHLYDAFISLAKTLHADPGDDPGTPSPSPEVIRSLKTLLVQLPDSNYNTLRHLVAH 692

Query: 250 LYQTAKKQDKNKMSAYNLALMFAPHVLWPKNVTANDLQENIT-KLNSG-----MAFMIKH 303
           L++ A +  +NKMSA NL ++F P +L P +         +T  L+SG     + F+I H
Sbjct: 693 LFRVAARFMENKMSANNLGIVFGPTLLRPPDGPRAASAIPVTCLLDSGHQAQLVEFLIVH 752

Query: 304 SQKLF 308
            +++F
Sbjct: 753 YEQIF 757


>gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo
           sapiens]
          Length = 655

 Score = 81.6 bits (200), Expect = 1e-15
 Identities = 58/193 (30%), Positives = 98/193 (50%), Gaps = 14/193 (7%)

Query: 125 IYQLIEYLH-KNLRVEGLFRVPGNSVRQQILRDALNNGTDIDLESG-EFHSNDVATLLKM 182
           + Q ++++  + L+ EGLFR+PG +   + L+DA + G     +S  + H+  VA+LLK+
Sbjct: 63  VEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHT--VASLLKL 120

Query: 183 FLGELPEPLLTHKHFNAHLKIADLMQFDDKGNKTNIPDKDRQIEALQLLFLILPPPNRNL 242
           +L ELPEP++ +  +   L  A L+    K  +  + +  +Q+++L       P  N NL
Sbjct: 121 YLRELPEPVIPYAKYEDFLSCAKLLS---KEEEAGVKELAKQVKSL-------PVVNYNL 170

Query: 243 LKLLLDLLYQTAKKQDKNKMSAYNLALMFAPHVLWPKNVTANDLQENITKLNSGMAFMIK 302
           LK +   L +       NKMS  NLA +F P++L PK      + E    +   M+ MI 
Sbjct: 171 LKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMIS 230

Query: 303 HSQKLFKAPAYIR 315
               LF   A ++
Sbjct: 231 KHDCLFPKDAELQ 243


>gi|134304853 PTPL1-associated RhoGAP 1 [Homo sapiens]
          Length = 1261

 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 58/220 (26%), Positives = 115/220 (52%), Gaps = 24/220 (10%)

Query: 112 IFGSPLTE------EGIAQIYQLI--EYLHKNLRVEGLFRVPGNSVRQQILRDALNNGTD 163
           +FG+  T+      +GI  I ++   E  ++ L ++G++RV GN ++ + L  AL NG  
Sbjct: 668 LFGAEFTQVAKKEPDGIPFILKICASEIENRALCLQGIYRVCGNKIKTEKLCQALENGMH 727

Query: 164 IDLESGEFHSNDVATLLKMFLGELPEPLLTHKHFNAHLKIADLMQF---DDKGNKTNIPD 220
           + ++  EF S+D+  +LK++L +LPEP +  + +   + +A  +Q    + +  K ++ D
Sbjct: 728 L-VDISEFSSHDICDVLKLYLRQLPEPFILFRLYKEFIDLAKEIQHVNEEQETKKNSLED 786

Query: 221 KDRQIEALQL---------LFLILPPPNRNLLKLLLDLLYQTAKKQDKNKMSAYNLALMF 271
           K      +++         L   LP  N N L  L+  L +     ++NKM++ NL ++F
Sbjct: 787 KKWPNMCIEINRILLKSKDLLRQLPASNFNSLHFLIVHLKRVVDHAEENKMNSKNLGVIF 846

Query: 272 APHVLWPKNVTANDLQENITKLNSG---MAFMIKHSQKLF 308
            P ++ P+  TA     ++ + ++    + F+I +SQK+F
Sbjct: 847 GPSLIRPRPTTAPITISSLAEYSNQARLVEFLITYSQKIF 886


>gi|7382480 Rho GTPase activating protein 6 isoform 4 [Homo sapiens]
          Length = 771

 Score = 80.1 bits (196), Expect = 4e-15
 Identities = 62/201 (30%), Positives = 101/201 (50%), Gaps = 33/201 (16%)

Query: 130 EYLHKN-LRVEGLFRVPGNSVRQQILRDALNNGTDIDLESGEFHSNDVATLLKMFLGELP 188
           ++L K+ L+  G+FRV  +  R + LR+  + G D+ LE  E   +DVA LLK FL ++P
Sbjct: 216 QHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEE-EHSVHDVAALLKEFLRDMP 274

Query: 189 EPLLTHKHFNAHLKIADLMQFDDKGNKTNIPDKDRQIEALQLLFLILPPPNRNLLKLLLD 248
           +PLLT + + A +              T + + + Q+  LQLL  +LPP N + L  LL 
Sbjct: 275 DPLLTRELYTAFI-------------NTLLLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQ 321

Query: 249 LLYQTAKKQDK-----------NKMSAYNLALMFAPHVLWPK-------NVTANDLQENI 290
            L   A+  D            NKM++ NLA +F P++L  +       +V ++   E  
Sbjct: 322 FLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEES 381

Query: 291 TKLNSGMAFMIKHSQKLFKAP 311
           T + + +  MI++ + LF  P
Sbjct: 382 TAIIAVVQKMIENYEALFMVP 402


>gi|95091988 Rho GTPase activating protein 6 isoform 3 [Homo
           sapiens]
          Length = 765

 Score = 80.1 bits (196), Expect = 4e-15
 Identities = 62/201 (30%), Positives = 101/201 (50%), Gaps = 33/201 (16%)

Query: 130 EYLHKN-LRVEGLFRVPGNSVRQQILRDALNNGTDIDLESGEFHSNDVATLLKMFLGELP 188
           ++L K+ L+  G+FRV  +  R + LR+  + G D+ LE  E   +DVA LLK FL ++P
Sbjct: 419 QHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEE-EHSVHDVAALLKEFLRDMP 477

Query: 189 EPLLTHKHFNAHLKIADLMQFDDKGNKTNIPDKDRQIEALQLLFLILPPPNRNLLKLLLD 248
           +PLLT + + A +              T + + + Q+  LQLL  +LPP N + L  LL 
Sbjct: 478 DPLLTRELYTAFI-------------NTLLLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQ 524

Query: 249 LLYQTAKKQDK-----------NKMSAYNLALMFAPHVLWPK-------NVTANDLQENI 290
            L   A+  D            NKM++ NLA +F P++L  +       +V ++   E  
Sbjct: 525 FLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEES 584

Query: 291 TKLNSGMAFMIKHSQKLFKAP 311
           T + + +  MI++ + LF  P
Sbjct: 585 TAIIAVVQKMIENYEALFMVP 605


>gi|95091875 Rho GTPase activating protein 6 isoform 1 [Homo
           sapiens]
          Length = 974

 Score = 80.1 bits (196), Expect = 4e-15
 Identities = 62/201 (30%), Positives = 101/201 (50%), Gaps = 33/201 (16%)

Query: 130 EYLHKN-LRVEGLFRVPGNSVRQQILRDALNNGTDIDLESGEFHSNDVATLLKMFLGELP 188
           ++L K+ L+  G+FRV  +  R + LR+  + G D+ LE  E   +DVA LLK FL ++P
Sbjct: 419 QHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEE-EHSVHDVAALLKEFLRDMP 477

Query: 189 EPLLTHKHFNAHLKIADLMQFDDKGNKTNIPDKDRQIEALQLLFLILPPPNRNLLKLLLD 248
           +PLLT + + A +              T + + + Q+  LQLL  +LPP N + L  LL 
Sbjct: 478 DPLLTRELYTAFI-------------NTLLLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQ 524

Query: 249 LLYQTAKKQDK-----------NKMSAYNLALMFAPHVLWPK-------NVTANDLQENI 290
            L   A+  D            NKM++ NLA +F P++L  +       +V ++   E  
Sbjct: 525 FLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEES 584

Query: 291 TKLNSGMAFMIKHSQKLFKAP 311
           T + + +  MI++ + LF  P
Sbjct: 585 TAIIAVVQKMIENYEALFMVP 605


>gi|4757766 Rho GTPase activating protein 1 [Homo sapiens]
          Length = 439

 Score = 79.0 bits (193), Expect = 9e-15
 Identities = 59/187 (31%), Positives = 93/187 (49%), Gaps = 19/187 (10%)

Query: 127 QLIEYLHKN-LRVEGLFRVPGNSVRQQILRDALNNGTDIDLES-GEFHSNDVATLLKMFL 184
           + + YL  + L  EG+FR   N+   + ++   N G  +D +   E H    A +LK FL
Sbjct: 265 ETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMGLPVDFDQYNELHLP--AVILKTFL 322

Query: 185 GELPEPLLTHKHFNAHLKIADLMQFDDKGNKTNIPDKDRQIEALQLLFLILPPPNRNLLK 244
            ELPEPLLT   F+ +  +   +         NI +  R    LQ+L   LP  N  +L+
Sbjct: 323 RELPEPLLT---FDLYPHVVGFL---------NIDESQRVPATLQVL-QTLPEENYQVLR 369

Query: 245 LLLDLLYQTAKKQDKNKMSAYNLALMFAPHVLWPKNVTANDLQENITKLNSGMAFMIKHS 304
            L   L Q +   D+NKM+  NLA++F P++LW K+       + I  +N+   F++ H 
Sbjct: 370 FLTAFLVQISAHSDQNKMTNTNLAVVFGPNLLWAKDAAIT--LKAINPINTFTKFLLDHQ 427

Query: 305 QKLFKAP 311
            +LF +P
Sbjct: 428 GELFPSP 434


>gi|26986534 Rho GTPase activating protein 12 [Homo sapiens]
          Length = 846

 Score = 79.0 bits (193), Expect = 9e-15
 Identities = 62/192 (32%), Positives = 98/192 (51%), Gaps = 28/192 (14%)

Query: 107 KEKGVI----FGSPLT-----EEGIAQ--IYQLIEYLHKN-LRVEGLFRVPGNSVRQQIL 154
           +EKG I    FGS L      E G     +   IE++ ++ L ++G++RV GN    Q L
Sbjct: 644 REKGYIKDQVFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKL 703

Query: 155 RDALNNGTDIDLESGEFHSNDVAT-LLKMFLGELPEPLLTHKHFNAHLKIADLMQFDDKG 213
           R A+N+   +DL   ++    V T  LKMF  ELPEPL T  HFN  +            
Sbjct: 704 RFAVNHDEKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNA---------- 753

Query: 214 NKTNIPDKDRQ-IEALQLLFLILPPPNRNLLKLLLDLLYQTAKKQDKNKMSAYNLALMFA 272
               I  + RQ + A++ L   LP PN++ +++L   L +  +  +KN+M+  ++A++F 
Sbjct: 754 ----IKQEPRQRVAAVKDLIRQLPKPNQDTMQILFRHLRRVIENGEKNRMTYQSIAIVFG 809

Query: 273 PHVLWPKNVTAN 284
           P +L P+  T N
Sbjct: 810 PTLLKPEKETGN 821


>gi|34013590 Rho GTPase activating protein 2 [Homo sapiens]
          Length = 698

 Score = 77.0 bits (188), Expect = 4e-14
 Identities = 79/304 (25%), Positives = 132/304 (43%), Gaps = 54/304 (17%)

Query: 44  FFVEKLRHEKPEIFTELVVSNITRLI---DLPGTELAQLMGEVDLKLPGGAG-----PAS 95
           F+ +     KP+ F  L  + +T L    + PG  L ++        PGGAG     PA+
Sbjct: 67  FYYKDKDEIKPQGFISLQGTQVTELPPGPEDPGKHLFEIS-------PGGAGEREKVPAN 119

Query: 96  GFFRSLMSLKRKEK----------------GVIFGSPLTEEGIAQ-----------IYQL 128
                LM+  +++                 G IFG  L E    +           + Q 
Sbjct: 120 PEALLLMASSQRDMEDWVQAIRRVIWAPLGGGIFGQRLEETVHHERKYGPRLAPLLVEQC 179

Query: 129 IEYLH-KNLRVEGLFRVPGNSVRQQILRDALNNGTDIDLESGEFHSNDVATLLKMFLGEL 187
           ++++  + L  EGLFR+PG +   + L+D+ + G +  L       + VA+LLK++L EL
Sbjct: 180 VDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCG-EKPLFDSTTDVHTVASLLKLYLREL 238

Query: 188 PEPLLTHKHFNAHLKIADLMQFDDKGNKTNIPDKDRQIEALQLLFLILPPPNRNLLKLLL 247
           PEP++    +   L  A L+  D+      +    +Q+  L       P  N NLL+ + 
Sbjct: 239 PEPVVPFARYEDFLSCAQLLTKDEGEGTLELA---KQVSNL-------PQANYNLLRYIC 288

Query: 248 DLLYQTAKKQDKNKMSAYNLALMFAPHVLWPKNVTANDLQENITKLNSGMAFMIKHSQKL 307
             L +     + NKMS  NLA +F P++L P+      + E  + +   M  +I+   +L
Sbjct: 289 KFLDEVQAYSNVNKMSVQNLATVFGPNILRPQVEDPVTIMEGTSLVQHLMTVLIRKHSQL 348

Query: 308 FKAP 311
           F AP
Sbjct: 349 FTAP 352


>gi|33188433 deleted in liver cancer 1 isoform 1 [Homo sapiens]
          Length = 1528

 Score = 76.6 bits (187), Expect = 5e-14
 Identities = 73/234 (31%), Positives = 109/234 (46%), Gaps = 43/234 (18%)

Query: 112  IFGSPLTE------EGIAQ-IYQLIEYLHKN-LRVEGLFRVPGNSVRQQILRDALNNGTD 163
            +FG PLT       + + Q I Q + YL  + L   GLFR  G   R Q LR  +N G  
Sbjct: 1075 VFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQ-MNEGA- 1132

Query: 164  IDLESGEFHSN-DVATLLKMFLGELPEPLLTHKHFNAHLKIADLMQFDDKGNKTNIPDKD 222
            ID  + E  S  DVA +LK +  +LPEPL+T+K     L+I   +             KD
Sbjct: 1133 IDCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVP------------KD 1180

Query: 223  RQIEALQLLFLILPPPNRNLLKLLLDLLYQTAKKQDKNKMSAYNLALMFAP---HVLWPK 279
            ++++A++   ++LP  NR +L+ LL  L        +N+M+  NLA+  AP   H+   K
Sbjct: 1181 QRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLK 1240

Query: 280  NVTAN----------------DLQENITKLNSGMAFMIKHSQKLFKAPAYIREC 317
               ++                DL EN+     G+A MI   +KLF+ P  +  C
Sbjct: 1241 RENSSPRVMQRKQSLGKPDQKDLNENLA-ATQGLAHMIAECKKLFQVPEEMSRC 1293


>gi|33188437 deleted in liver cancer 1 isoform 2 [Homo sapiens]
          Length = 1091

 Score = 76.6 bits (187), Expect = 5e-14
 Identities = 73/234 (31%), Positives = 109/234 (46%), Gaps = 43/234 (18%)

Query: 112 IFGSPLTE------EGIAQ-IYQLIEYLHKN-LRVEGLFRVPGNSVRQQILRDALNNGTD 163
           +FG PLT       + + Q I Q + YL  + L   GLFR  G   R Q LR  +N G  
Sbjct: 638 VFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQ-MNEGA- 695

Query: 164 IDLESGEFHSN-DVATLLKMFLGELPEPLLTHKHFNAHLKIADLMQFDDKGNKTNIPDKD 222
           ID  + E  S  DVA +LK +  +LPEPL+T+K     L+I   +             KD
Sbjct: 696 IDCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVP------------KD 743

Query: 223 RQIEALQLLFLILPPPNRNLLKLLLDLLYQTAKKQDKNKMSAYNLALMFAP---HVLWPK 279
           ++++A++   ++LP  NR +L+ LL  L        +N+M+  NLA+  AP   H+   K
Sbjct: 744 QRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLK 803

Query: 280 NVTAN----------------DLQENITKLNSGMAFMIKHSQKLFKAPAYIREC 317
              ++                DL EN+     G+A MI   +KLF+ P  +  C
Sbjct: 804 RENSSPRVMQRKQSLGKPDQKDLNENLA-ATQGLAHMIAECKKLFQVPEEMSRC 856


>gi|194272142 myosin IXB isoform 2 [Homo sapiens]
          Length = 2022

 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 56/186 (30%), Positives = 95/186 (51%), Gaps = 17/186 (9%)

Query: 127  QLIEYLHKN-LRVEGLFRVPGNSVRQQILRDALNNG-TDIDLESGEFHSNDVATLLKMFL 184
            +L+E++  + L  EGL+R  G + R + LR AL      + LE+   H+  +  +LK +L
Sbjct: 1718 KLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTDPAAVKLENFPIHA--ITGVLKQWL 1775

Query: 185  GELPEPLLTHKHFNAHLKIADLMQFDDKGNKTNIPDKDRQIEALQLLFLILPPPNRNLLK 244
             ELPEPL+T   +   L+  +L            P+K  Q+ A+  +   LP  N N L+
Sbjct: 1776 RELPEPLMTFAQYGDFLRAVEL------------PEKQEQLAAIYAVLEHLPEANHNSLE 1823

Query: 245  LLLDLLYQTAKKQDKNKMSAYNLALMFAPHVL-WPKNVTANDLQENITKLNSGMAFMIKH 303
             L+  L + A  +D N+MS   LA++FAP +L  P N       +++ K+ + +  +IK 
Sbjct: 1824 RLIFHLVKVALLEDVNRMSPGALAIIFAPCLLRCPDNSDPLTSMKDVLKITTCVEMLIKE 1883

Query: 304  SQKLFK 309
              + +K
Sbjct: 1884 QMRKYK 1889


>gi|33356170 myosin IXB isoform 1 [Homo sapiens]
          Length = 2157

 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 56/186 (30%), Positives = 95/186 (51%), Gaps = 17/186 (9%)

Query: 127  QLIEYLHKN-LRVEGLFRVPGNSVRQQILRDALNNG-TDIDLESGEFHSNDVATLLKMFL 184
            +L+E++  + L  EGL+R  G + R + LR AL      + LE+   H+  +  +LK +L
Sbjct: 1718 KLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTDPAAVKLENFPIHA--ITGVLKQWL 1775

Query: 185  GELPEPLLTHKHFNAHLKIADLMQFDDKGNKTNIPDKDRQIEALQLLFLILPPPNRNLLK 244
             ELPEPL+T   +   L+  +L            P+K  Q+ A+  +   LP  N N L+
Sbjct: 1776 RELPEPLMTFAQYGDFLRAVEL------------PEKQEQLAAIYAVLEHLPEANHNSLE 1823

Query: 245  LLLDLLYQTAKKQDKNKMSAYNLALMFAPHVL-WPKNVTANDLQENITKLNSGMAFMIKH 303
             L+  L + A  +D N+MS   LA++FAP +L  P N       +++ K+ + +  +IK 
Sbjct: 1824 RLIFHLVKVALLEDVNRMSPGALAIIFAPCLLRCPDNSDPLTSMKDVLKITTCVEMLIKE 1883

Query: 304  SQKLFK 309
              + +K
Sbjct: 1884 QMRKYK 1889


>gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens]
          Length = 818

 Score = 73.9 bits (180), Expect = 3e-13
 Identities = 48/170 (28%), Positives = 93/170 (54%), Gaps = 19/170 (11%)

Query: 132 LHKNLRVEGLFRVPGNSVRQQILRDALNNGTDIDLESGEFHSNDVATLLKMFLGELPEPL 191
           L   ++ EGLFRV  ++ + + L+ AL+    +D++      + +A  LK +L ELPEPL
Sbjct: 280 LECGMQEEGLFRVAPSASKLKKLKAALDCCV-VDVQEYSADPHAIAGALKSYLRELPEPL 338

Query: 192 LTHKHFNAHLKIADLMQFDDKGNKTNIPDKDRQIEALQLLFLILPPPNRNLLKLLLDLLY 251
           +T +             +D+    +N+ ++D++++AL      LP  N N ++ L+  L 
Sbjct: 339 MTFE------------LYDEWIQASNVQEQDKKLQALWNACEKLPKANHNNIRYLIKFLS 386

Query: 252 QTAKKQDKNKMSAYNLALMFAPHVLWPKNVTANDLQENITKLNSGMAFMI 301
           + ++ QD NKM+  N+A++  P++LWP+       + NIT++ + ++  I
Sbjct: 387 KLSEYQDVNKMTPSNMAIVLGPNLLWPQ------AEGNITEMMTTVSLQI 430


>gi|41281907 StAR-related lipid transfer (START) domain containing
           13 isoform beta [Homo sapiens]
          Length = 1105

 Score = 73.2 bits (178), Expect = 5e-13
 Identities = 71/252 (28%), Positives = 109/252 (43%), Gaps = 40/252 (15%)

Query: 98  FRSLMSLKRKEKGVIFGSPL------TEEGIAQ-IYQLIEYLHKN-LRVEGLFRVPGNSV 149
           F   M +   +   +FG PL      T + + Q I Q + YL  N L   GLFR  G   
Sbjct: 638 FMKRMKVPDYKDKAVFGVPLIVHVQRTGQPLPQSIQQALRYLRSNCLDQVGLFRKSGVKS 697

Query: 150 RQQILRDALNNGTDIDLESGEFHSNDVATLLKMFLGELPEPLLTHKHFNAHLKIADLMQF 209
           R   LR  +N     ++   +  + DVA ++K F  +LPEPL T+K     L I   +  
Sbjct: 698 RIHALRQ-MNENFPENVNYEDQSAYDVADMVKQFFRDLPEPLFTNKLSETFLHIYQYVS- 755

Query: 210 DDKGNKTNIPDKDRQIEALQLLFLILPPPNRNLLKLLLDLLYQTAKKQDKNKMSAYNLAL 269
                      K+++++A+Q   L+L   NR +L+ LL  L       ++N+M+  NLA+
Sbjct: 756 -----------KEQRLQAVQAAILLLADENREVLQTLLCFLNDVVNLVEENQMTPMNLAV 804

Query: 270 MFA--------------PHVLWPKNVTA----NDLQENITKLNSGMAFMIKHSQKLFKAP 311
             A              P V+  K  T      DL EN+     G+A MI    +LF+ P
Sbjct: 805 CLAPSLFHLNLLKKESSPRVIQKKYATGKPDQKDLNENLAAA-QGLAHMIMECDRLFEVP 863

Query: 312 AYIRECARLHYL 323
             +   +R  Y+
Sbjct: 864 HELVAQSRNSYV 875


>gi|16445031 StAR-related lipid transfer (START) domain containing
           13 isoform gamma [Homo sapiens]
          Length = 995

 Score = 73.2 bits (178), Expect = 5e-13
 Identities = 71/252 (28%), Positives = 109/252 (43%), Gaps = 40/252 (15%)

Query: 98  FRSLMSLKRKEKGVIFGSPL------TEEGIAQ-IYQLIEYLHKN-LRVEGLFRVPGNSV 149
           F   M +   +   +FG PL      T + + Q I Q + YL  N L   GLFR  G   
Sbjct: 528 FMKRMKVPDYKDKAVFGVPLIVHVQRTGQPLPQSIQQALRYLRSNCLDQVGLFRKSGVKS 587

Query: 150 RQQILRDALNNGTDIDLESGEFHSNDVATLLKMFLGELPEPLLTHKHFNAHLKIADLMQF 209
           R   LR  +N     ++   +  + DVA ++K F  +LPEPL T+K     L I   +  
Sbjct: 588 RIHALRQ-MNENFPENVNYEDQSAYDVADMVKQFFRDLPEPLFTNKLSETFLHIYQYVS- 645

Query: 210 DDKGNKTNIPDKDRQIEALQLLFLILPPPNRNLLKLLLDLLYQTAKKQDKNKMSAYNLAL 269
                      K+++++A+Q   L+L   NR +L+ LL  L       ++N+M+  NLA+
Sbjct: 646 -----------KEQRLQAVQAAILLLADENREVLQTLLCFLNDVVNLVEENQMTPMNLAV 694

Query: 270 MFA--------------PHVLWPKNVTA----NDLQENITKLNSGMAFMIKHSQKLFKAP 311
             A              P V+  K  T      DL EN+     G+A MI    +LF+ P
Sbjct: 695 CLAPSLFHLNLLKKESSPRVIQKKYATGKPDQKDLNENLAAA-QGLAHMIMECDRLFEVP 753

Query: 312 AYIRECARLHYL 323
             +   +R  Y+
Sbjct: 754 HELVAQSRNSYV 765


>gi|41281898 StAR-related lipid transfer (START) domain containing
           13 isoform alpha [Homo sapiens]
          Length = 1113

 Score = 73.2 bits (178), Expect = 5e-13
 Identities = 71/252 (28%), Positives = 109/252 (43%), Gaps = 40/252 (15%)

Query: 98  FRSLMSLKRKEKGVIFGSPL------TEEGIAQ-IYQLIEYLHKN-LRVEGLFRVPGNSV 149
           F   M +   +   +FG PL      T + + Q I Q + YL  N L   GLFR  G   
Sbjct: 646 FMKRMKVPDYKDKAVFGVPLIVHVQRTGQPLPQSIQQALRYLRSNCLDQVGLFRKSGVKS 705

Query: 150 RQQILRDALNNGTDIDLESGEFHSNDVATLLKMFLGELPEPLLTHKHFNAHLKIADLMQF 209
           R   LR  +N     ++   +  + DVA ++K F  +LPEPL T+K     L I   +  
Sbjct: 706 RIHALRQ-MNENFPENVNYEDQSAYDVADMVKQFFRDLPEPLFTNKLSETFLHIYQYVS- 763

Query: 210 DDKGNKTNIPDKDRQIEALQLLFLILPPPNRNLLKLLLDLLYQTAKKQDKNKMSAYNLAL 269
                      K+++++A+Q   L+L   NR +L+ LL  L       ++N+M+  NLA+
Sbjct: 764 -----------KEQRLQAVQAAILLLADENREVLQTLLCFLNDVVNLVEENQMTPMNLAV 812

Query: 270 MFA--------------PHVLWPKNVTA----NDLQENITKLNSGMAFMIKHSQKLFKAP 311
             A              P V+  K  T      DL EN+     G+A MI    +LF+ P
Sbjct: 813 CLAPSLFHLNLLKKESSPRVIQKKYATGKPDQKDLNENLAAA-QGLAHMIMECDRLFEVP 871

Query: 312 AYIRECARLHYL 323
             +   +R  Y+
Sbjct: 872 HELVAQSRNSYV 883


>gi|226693398 Rho GTPase activating protein 27 isoform b [Homo
           sapiens]
          Length = 521

 Score = 72.4 bits (176), Expect = 9e-13
 Identities = 44/147 (29%), Positives = 75/147 (51%), Gaps = 13/147 (8%)

Query: 134 KNLRVEGLFRVPGNSVRQQILRDALNNGTDIDLESGEFHSNDVAT-LLKMFLGELPEPLL 192
           + L ++GL+R+ GN    Q LR  +++   +DL+ G +    V T  LK+F  ELPEPL 
Sbjct: 356 RGLDIDGLYRISGNLATIQKLRYKVDHDERLDLDDGRWEDVHVITGALKLFFRELPEPLF 415

Query: 193 THKHFNAHLKIADLMQFDDKGNKTNIPDKDRQIEALQLLFLILPPPNRNLLKLLLDLLYQ 252
              HF   +    L             D+ R+   ++ L   LP PN + L++L   L +
Sbjct: 416 PFSHFRQFIAAIKLQ------------DQARRSRCVRDLVRSLPAPNHDTLRMLFQHLCR 463

Query: 253 TAKKQDKNKMSAYNLALMFAPHVLWPK 279
             +  ++N+MS  ++A++F P +L P+
Sbjct: 464 VIEHGEQNRMSVQSVAIVFGPTLLRPE 490


>gi|40548322 Rho GTPase activating protein 27 isoform a [Homo
           sapiens]
          Length = 548

 Score = 72.4 bits (176), Expect = 9e-13
 Identities = 44/147 (29%), Positives = 75/147 (51%), Gaps = 13/147 (8%)

Query: 134 KNLRVEGLFRVPGNSVRQQILRDALNNGTDIDLESGEFHSNDVAT-LLKMFLGELPEPLL 192
           + L ++GL+R+ GN    Q LR  +++   +DL+ G +    V T  LK+F  ELPEPL 
Sbjct: 383 RGLDIDGLYRISGNLATIQKLRYKVDHDERLDLDDGRWEDVHVITGALKLFFRELPEPLF 442

Query: 193 THKHFNAHLKIADLMQFDDKGNKTNIPDKDRQIEALQLLFLILPPPNRNLLKLLLDLLYQ 252
              HF   +    L             D+ R+   ++ L   LP PN + L++L   L +
Sbjct: 443 PFSHFRQFIAAIKLQ------------DQARRSRCVRDLVRSLPAPNHDTLRMLFQHLCR 490

Query: 253 TAKKQDKNKMSAYNLALMFAPHVLWPK 279
             +  ++N+MS  ++A++F P +L P+
Sbjct: 491 VIEHGEQNRMSVQSVAIVFGPTLLRPE 517


>gi|206597515 ArfGAP with RhoGAP domain, ankyrin repeat and PH
           domain 1 isoform d [Homo sapiens]
          Length = 1133

 Score = 72.4 bits (176), Expect = 9e-13
 Identities = 45/151 (29%), Positives = 81/151 (53%), Gaps = 14/151 (9%)

Query: 125 IYQLIEYLHK-NLRVEGLFRVPGNSVRQQILRDALN-NGTDIDLESGEFHSNDVATLLKM 182
           +Y+ ++Y+ +  L  EG++R  G + + Q L ++L  +   + L+ GE H +DV++ LK 
Sbjct: 668 VYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKR 727

Query: 183 FLGELPEPLLTHKHFNAHLKIADLMQFDDKGNKTNIPDKDRQIEALQLLFLILPPPNRNL 242
           FL +LP+ L T       L+ ++            I D++ ++   + L + LPP NR  
Sbjct: 728 FLRDLPDGLFTRAQRLTWLEASE------------IEDEEEKVSRYRELLVRLPPVNRAT 775

Query: 243 LKLLLDLLYQTAKKQDKNKMSAYNLALMFAP 273
           +K L+  LY      D N+M+ +NLA++F P
Sbjct: 776 VKALISHLYCVQCFSDTNQMNVHNLAIVFGP 806


>gi|206597513 ArfGAP with RhoGAP domain, ankyrin repeat and PH
           domain 1 isoform a [Homo sapiens]
          Length = 1205

 Score = 72.4 bits (176), Expect = 9e-13
 Identities = 45/151 (29%), Positives = 81/151 (53%), Gaps = 14/151 (9%)

Query: 125 IYQLIEYLHK-NLRVEGLFRVPGNSVRQQILRDALN-NGTDIDLESGEFHSNDVATLLKM 182
           +Y+ ++Y+ +  L  EG++R  G + + Q L ++L  +   + L+ GE H +DV++ LK 
Sbjct: 729 VYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKR 788

Query: 183 FLGELPEPLLTHKHFNAHLKIADLMQFDDKGNKTNIPDKDRQIEALQLLFLILPPPNRNL 242
           FL +LP+ L T       L+ ++            I D++ ++   + L + LPP NR  
Sbjct: 789 FLRDLPDGLFTRAQRLTWLEASE------------IEDEEEKVSRYRELLVRLPPVNRAT 836

Query: 243 LKLLLDLLYQTAKKQDKNKMSAYNLALMFAP 273
           +K L+  LY      D N+M+ +NLA++F P
Sbjct: 837 VKALISHLYCVQCFSDTNQMNVHNLAIVFGP 867


>gi|92091600 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
            isoform c [Homo sapiens]
          Length = 1450

 Score = 72.4 bits (176), Expect = 9e-13
 Identities = 45/151 (29%), Positives = 81/151 (53%), Gaps = 14/151 (9%)

Query: 125  IYQLIEYLHK-NLRVEGLFRVPGNSVRQQILRDALN-NGTDIDLESGEFHSNDVATLLKM 182
            +Y+ ++Y+ +  L  EG++R  G + + Q L ++L  +   + L+ GE H +DV++ LK 
Sbjct: 974  VYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKR 1033

Query: 183  FLGELPEPLLTHKHFNAHLKIADLMQFDDKGNKTNIPDKDRQIEALQLLFLILPPPNRNL 242
            FL +LP+ L T       L+ ++            I D++ ++   + L + LPP NR  
Sbjct: 1034 FLRDLPDGLFTRAQRLTWLEASE------------IEDEEEKVSRYRELLVRLPPVNRAT 1081

Query: 243  LKLLLDLLYQTAKKQDKNKMSAYNLALMFAP 273
            +K L+  LY      D N+M+ +NLA++F P
Sbjct: 1082 VKALISHLYCVQCFSDTNQMNVHNLAIVFGP 1112


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.379 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,248,043
Number of Sequences: 37866
Number of extensions: 867289
Number of successful extensions: 2840
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 102
Number of HSP's successfully gapped in prelim test: 46
Number of HSP's that attempted gapping in prelim test: 2542
Number of HSP's gapped (non-prelim): 185
length of query: 494
length of database: 18,247,518
effective HSP length: 106
effective length of query: 388
effective length of database: 14,233,722
effective search space: 5522684136
effective search space used: 5522684136
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.