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Search of human proteins with 67782311
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|67782311 superkiller viralicidic activity 2-like homolog
[Homo sapiens]
(1246 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|67782311 superkiller viralicidic activity 2-like homolog [Hom... 2481 0.0
gi|193211480 superkiller viralicidic activity 2-like 2 [Homo sap... 573 e-163
gi|130484567 HFM1 protein [Homo sapiens] 114 6e-25
gi|40217847 activating signal cointegrator 1 complex subunit 3-l... 112 2e-24
gi|169218225 PREDICTED: similar to U5 snRNP-specific 200kD prote... 107 5e-23
gi|76880486 activating signal cointegrator 1 complex subunit 3 i... 104 6e-22
gi|139394648 DNA polymerase theta [Homo sapiens] 90 2e-17
gi|149274648 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like [Hom... 89 3e-17
gi|222831595 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 [Homo sap... 80 2e-14
gi|110556640 DNA helicase HEL308 [Homo sapiens] 65 5e-10
gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2 ... 39 0.024
gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1... 39 0.024
gi|150418009 transforming, acidic coiled-coil containing protein... 39 0.040
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 38 0.053
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 38 0.053
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap... 38 0.053
gi|83367077 mucin 16 [Homo sapiens] 37 0.090
gi|14591902 RecQ protein-like [Homo sapiens] 37 0.090
gi|14591904 RecQ protein-like [Homo sapiens] 37 0.090
gi|38570099 glutamine-rich 1 [Homo sapiens] 37 0.15
gi|38570097 glutamine-rich 1 [Homo sapiens] 37 0.15
gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens] 36 0.20
gi|110735439 Werner syndrome protein [Homo sapiens] 35 0.34
gi|169218196 PREDICTED: similar to Werner syndrome ATP-dependent... 35 0.34
gi|116812616 RecQ protein-like 4 [Homo sapiens] 35 0.58
gi|31543667 suppressor of var1, 3-like 1 [Homo sapiens] 35 0.58
gi|148596977 zinc finger protein 31 [Homo sapiens] 35 0.58
gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo sapi... 34 1.00
gi|13129006 nucleolar protein GU2 [Homo sapiens] 34 1.00
gi|45827755 transforming, acidic coiled-coil containing protein ... 34 1.00
>gi|67782311 superkiller viralicidic activity 2-like homolog [Homo
sapiens]
Length = 1246
Score = 2481 bits (6430), Expect = 0.0
Identities = 1246/1246 (100%), Positives = 1246/1246 (100%)
Query: 1 MMETERLVLPPPDPLDLPLRAVELGCTGHWELLNLPGAPESSLPHGLPPCAPDLQQEAEQ 60
MMETERLVLPPPDPLDLPLRAVELGCTGHWELLNLPGAPESSLPHGLPPCAPDLQQEAEQ
Sbjct: 1 MMETERLVLPPPDPLDLPLRAVELGCTGHWELLNLPGAPESSLPHGLPPCAPDLQQEAEQ 60
Query: 61 LFLSSPAWLPLHGVEHSARKWQRKTDPWSLLAVLGAPVPSDLQAQRHPTTGQILGYKEVL 120
LFLSSPAWLPLHGVEHSARKWQRKTDPWSLLAVLGAPVPSDLQAQRHPTTGQILGYKEVL
Sbjct: 61 LFLSSPAWLPLHGVEHSARKWQRKTDPWSLLAVLGAPVPSDLQAQRHPTTGQILGYKEVL 120
Query: 121 LENTNLSATTSLSLRRPPGPASQSLWGNPTQYPFWPGGMDEPTITDLNTREEAEEEIDFE 180
LENTNLSATTSLSLRRPPGPASQSLWGNPTQYPFWPGGMDEPTITDLNTREEAEEEIDFE
Sbjct: 121 LENTNLSATTSLSLRRPPGPASQSLWGNPTQYPFWPGGMDEPTITDLNTREEAEEEIDFE 180
Query: 181 KDLLTIPPGFKKGMDFAPKDCPTPAPGLLSLSCMLEPLDLGGGDEDENEAVGQPGGPRGD 240
KDLLTIPPGFKKGMDFAPKDCPTPAPGLLSLSCMLEPLDLGGGDEDENEAVGQPGGPRGD
Sbjct: 181 KDLLTIPPGFKKGMDFAPKDCPTPAPGLLSLSCMLEPLDLGGGDEDENEAVGQPGGPRGD 240
Query: 241 TVSASPCSAPLARASSLEDLVLKEASTAVSTPEAPEPPSQEQWAIPVDATSPVGDFYRLI 300
TVSASPCSAPLARASSLEDLVLKEASTAVSTPEAPEPPSQEQWAIPVDATSPVGDFYRLI
Sbjct: 241 TVSASPCSAPLARASSLEDLVLKEASTAVSTPEAPEPPSQEQWAIPVDATSPVGDFYRLI 300
Query: 301 PQPAFQWAFEPDVFQKQAILHLERHDSVFVAAHTSAGKTVVAEYAIALAQKHMTRTIYTS 360
PQPAFQWAFEPDVFQKQAILHLERHDSVFVAAHTSAGKTVVAEYAIALAQKHMTRTIYTS
Sbjct: 301 PQPAFQWAFEPDVFQKQAILHLERHDSVFVAAHTSAGKTVVAEYAIALAQKHMTRTIYTS 360
Query: 361 PIKALSNQKFRDFRNTFGDVGLLTGDVQLHPEASCLIMTTEILRSMLYSGSDVIRDLEWV 420
PIKALSNQKFRDFRNTFGDVGLLTGDVQLHPEASCLIMTTEILRSMLYSGSDVIRDLEWV
Sbjct: 361 PIKALSNQKFRDFRNTFGDVGLLTGDVQLHPEASCLIMTTEILRSMLYSGSDVIRDLEWV 420
Query: 421 IFDEVHYINDVERGVVWEEVLIMLPDHVSIILLSATVPNALEFADWIGRLKRRQIYVIST 480
IFDEVHYINDVERGVVWEEVLIMLPDHVSIILLSATVPNALEFADWIGRLKRRQIYVIST
Sbjct: 421 IFDEVHYINDVERGVVWEEVLIMLPDHVSIILLSATVPNALEFADWIGRLKRRQIYVIST 480
Query: 481 VTRPVPLEHYLFTGNSSKTQGELFLLLDSRGAFHTKGYYAAVEAKKERMSKHAQTFGAKQ 540
VTRPVPLEHYLFTGNSSKTQGELFLLLDSRGAFHTKGYYAAVEAKKERMSKHAQTFGAKQ
Sbjct: 481 VTRPVPLEHYLFTGNSSKTQGELFLLLDSRGAFHTKGYYAAVEAKKERMSKHAQTFGAKQ 540
Query: 541 PTHQGGPAQDRGVYLSLLASLRTRAQLPVVVFTFSRGRCDEQASGLTSLDLTTSSEKSEI 600
PTHQGGPAQDRGVYLSLLASLRTRAQLPVVVFTFSRGRCDEQASGLTSLDLTTSSEKSEI
Sbjct: 541 PTHQGGPAQDRGVYLSLLASLRTRAQLPVVVFTFSRGRCDEQASGLTSLDLTTSSEKSEI 600
Query: 601 HLFLQRCLARLRGSDRQLPQVLHMSELLNRGLGVHHSGILPILKEIVEMLFSRGLVKVLF 660
HLFLQRCLARLRGSDRQLPQVLHMSELLNRGLGVHHSGILPILKEIVEMLFSRGLVKVLF
Sbjct: 601 HLFLQRCLARLRGSDRQLPQVLHMSELLNRGLGVHHSGILPILKEIVEMLFSRGLVKVLF 660
Query: 661 ATETFAMGVNMPARTVVFDSMRKHDGSTFRDLLPGEYVQMAGRAGRRGLDPTGTVILLCK 720
ATETFAMGVNMPARTVVFDSMRKHDGSTFRDLLPGEYVQMAGRAGRRGLDPTGTVILLCK
Sbjct: 661 ATETFAMGVNMPARTVVFDSMRKHDGSTFRDLLPGEYVQMAGRAGRRGLDPTGTVILLCK 720
Query: 721 GRVPEMADLHRMMMGKPSQLQSQFRLTYTMILNLLRVDALRVEDMMKRSFSEFPSRKDSK 780
GRVPEMADLHRMMMGKPSQLQSQFRLTYTMILNLLRVDALRVEDMMKRSFSEFPSRKDSK
Sbjct: 721 GRVPEMADLHRMMMGKPSQLQSQFRLTYTMILNLLRVDALRVEDMMKRSFSEFPSRKDSK 780
Query: 781 AHEQALAELTKRLGALEEPDMTGQLVDLPEYYSWGEELTETQHMIQRRIMESVNGLKSLS 840
AHEQALAELTKRLGALEEPDMTGQLVDLPEYYSWGEELTETQHMIQRRIMESVNGLKSLS
Sbjct: 781 AHEQALAELTKRLGALEEPDMTGQLVDLPEYYSWGEELTETQHMIQRRIMESVNGLKSLS 840
Query: 841 AGRVVVVKNQEHHNALGVILQVSSNSTSRVFTTLVLCDKPLSQDPQDRGPATAEVPYPDD 900
AGRVVVVKNQEHHNALGVILQVSSNSTSRVFTTLVLCDKPLSQDPQDRGPATAEVPYPDD
Sbjct: 841 AGRVVVVKNQEHHNALGVILQVSSNSTSRVFTTLVLCDKPLSQDPQDRGPATAEVPYPDD 900
Query: 901 LVGFKLFLPEGPCDHTVVKLQPGDMAAITTKVLRVNGEKILEDFSKRQQPKFKKDPPLAA 960
LVGFKLFLPEGPCDHTVVKLQPGDMAAITTKVLRVNGEKILEDFSKRQQPKFKKDPPLAA
Sbjct: 901 LVGFKLFLPEGPCDHTVVKLQPGDMAAITTKVLRVNGEKILEDFSKRQQPKFKKDPPLAA 960
Query: 961 VTTAVQELLRLAQAHPAGPPTLDPVNDLQLKDMSVVEGGLRARKLEELIQGAQCVHSPRF 1020
VTTAVQELLRLAQAHPAGPPTLDPVNDLQLKDMSVVEGGLRARKLEELIQGAQCVHSPRF
Sbjct: 961 VTTAVQELLRLAQAHPAGPPTLDPVNDLQLKDMSVVEGGLRARKLEELIQGAQCVHSPRF 1020
Query: 1021 PAQYLKLRERMQIQKEMERLRFLLSDQSLLLLPEYHQRVEVLRTLGYVDEAGTVKLAGRV 1080
PAQYLKLRERMQIQKEMERLRFLLSDQSLLLLPEYHQRVEVLRTLGYVDEAGTVKLAGRV
Sbjct: 1021 PAQYLKLRERMQIQKEMERLRFLLSDQSLLLLPEYHQRVEVLRTLGYVDEAGTVKLAGRV 1080
Query: 1081 ACAMSSHELLLTELMFDNALSTLRPEEIAALLSGLVCQSPGDAGDQLPNTLKQGIERVRA 1140
ACAMSSHELLLTELMFDNALSTLRPEEIAALLSGLVCQSPGDAGDQLPNTLKQGIERVRA
Sbjct: 1081 ACAMSSHELLLTELMFDNALSTLRPEEIAALLSGLVCQSPGDAGDQLPNTLKQGIERVRA 1140
Query: 1141 VAKRIGEVQVACGLNQTVEEFVGELNFGLVEVVYEWARGMPFSELAGLSGTPEGLVVRCI 1200
VAKRIGEVQVACGLNQTVEEFVGELNFGLVEVVYEWARGMPFSELAGLSGTPEGLVVRCI
Sbjct: 1141 VAKRIGEVQVACGLNQTVEEFVGELNFGLVEVVYEWARGMPFSELAGLSGTPEGLVVRCI 1200
Query: 1201 QRLAEMCRSLRGAARLVGEPVLGAKMETAATLLRRDIVFAASLYTQ 1246
QRLAEMCRSLRGAARLVGEPVLGAKMETAATLLRRDIVFAASLYTQ
Sbjct: 1201 QRLAEMCRSLRGAARLVGEPVLGAKMETAATLLRRDIVFAASLYTQ 1246
>gi|193211480 superkiller viralicidic activity 2-like 2 [Homo sapiens]
Length = 1042
Score = 573 bits (1478), Expect = e-163
Identities = 361/1004 (35%), Positives = 542/1004 (53%), Gaps = 68/1004 (6%)
Query: 256 SLEDLVLKEASTAVSTPEAPEPPSQEQWAIPVDATSPVGDFYRLIPQ---PAFQWAFEPD 312
SL DL+ + +V T E + A+P + D+ L P+ A ++ F D
Sbjct: 91 SLADLMPRVKVQSVETVEG----CTHEVALPAEE-----DYLPLKPRVGKAAKEYPFILD 141
Query: 313 VFQKQAILHLERHDSVFVAAHTSAGKTVVAEYAIALAQKHMTRTIYTSPIKALSNQKFRD 372
FQ++AI ++ + SV V+AHTSAGKTV AEYAIALA + R I+TSPIKALSNQK+R+
Sbjct: 142 AFQREAIQCVDNNQSVLVSAHTSAGKTVCAEYAIALALREKQRVIFTSPIKALSNQKYRE 201
Query: 373 FRNTFGDVGLLTGDVQLHPEASCLIMTTEILRSMLYSGSDVIRDLEWVIFDEVHYINDVE 432
F DVGL+TGDV ++P ASCL+MTTEILRSMLY GS+V+R++ WVIFDE+HY+ D E
Sbjct: 202 MYEEFQDVGLMTGDVTINPTASCLVMTTEILRSMLYRGSEVMREVAWVIFDEIHYMRDSE 261
Query: 433 RGVVWEEVLIMLPDHVSIILLSATVPNALEFADWIGRLKRRQIYVISTVTRPVPLEHYLF 492
RGVVWEE +I+LPD+V + LSAT+PNA +FA+WI L ++ +VI T RP PL+HY+F
Sbjct: 262 RGVVWEETIILLPDNVHYVFLSATIPNARQFAEWICHLHKQPCHVIYTDYRPTPLQHYIF 321
Query: 493 TGNSSKTQGELFLLLDSRGAFHTKGYYAAVEAKKERMSKHAQTFGAKQPTHQGGPAQDRG 552
L L++D G F + A++ ++ Q +GG
Sbjct: 322 PAGGD----GLHLVVDENGDFREDNFNTAMQVLRDA----GDLAKGDQKGRKGGTKGPSN 373
Query: 553 VYLSLLASLRTRAQLPVVVFTFSRGRCDEQASGLTSLDLTTSSEKSEIHLFLQRCLARLR 612
V+ ++ + R PV++F+FS+ C+ A +T LD T EK + + L
Sbjct: 374 VF-KIVKMIMERNFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMVEEVFSNAIDCLS 432
Query: 613 GSDRQLPQVLHMSELLNRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVNMP 672
D++LPQV H+ LL RG+G+HH G+LPILKE +E+LFS GL+K LFATETFAMG+NMP
Sbjct: 433 DEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLIKALFATETFAMGINMP 492
Query: 673 ARTVVFDSMRKHDGSTFRDLLPGEYVQMAGRAGRRGLDPTGTVILLCKGRVPEMADLHRM 732
ARTV+F + RK DG FR + GEY+QM+GRAGRRG+D G VIL+ ++ ++
Sbjct: 493 ARTVLFTNARKFDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEKMSPTIG-KQL 551
Query: 733 MMGKPSQLQSQFRLTYTMILNLLRVDALRVEDMMKRSFSEFPSRKDSKAHEQALAELTKR 792
+ G L S F LTY M+LNLLRV+ + E M+++SF +F + + + ++
Sbjct: 552 LKGSADPLNSAFHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAIPGVVEKVKNSEEQ 611
Query: 793 LGALEEPDMTGQLVDLPEYYSWGEELTETQHMIQRRIMESVNGLKSLSAGRVVVVKNQEH 852
+ P+ ++ YY ++L + I+ I + L L GR+V VKN+
Sbjct: 612 YNKIVIPNEESVVI----YYKIRQQLAKLGKEIEEYIHKPKYCLPFLQPGRLVKVKNEGD 667
Query: 853 HNALGVILQVSSNSTSR----------VFTTLVLCDKPLSQDPQDRGPATAEVPYPDDLV 902
GV++ S S + V L+ C K ++ A+
Sbjct: 668 DFGWGVVVNFSKKSNVKPNSGELDPLYVVEVLLRCSKESLKNSATEAAKPAK-------- 719
Query: 903 GFKLFLPEGPCDHTVVKLQPGDMAAITTKVLRVNGEKILEDFSKRQQPKFKKDPPLAAVT 962
P+ + VV + ++AI++ +R+ K L RQ +V
Sbjct: 720 ------PDEKGEMQVVPVLVHLLSAISS--VRLYIPKDLRPVDNRQ-----------SVL 760
Query: 963 TAVQELLRLAQAHPAGPPTLDPVNDLQLKDMSVVEGGLRARKLEELIQGAQCVHSPRFPA 1022
++QE + + P G P LDP++D+ ++D + + + E + + P
Sbjct: 761 KSIQE---VQKRFPDGIPLLDPIDDMGIQDQGLKKVIQKVEAFEHRMYSHPLHNDPNLET 817
Query: 1023 QYLKLRERMQIQKEMERL-RFLLSDQSLLLLPEYHQRVEVLRTLGYVDEAGTVKLAGRVA 1081
Y ++ QI +++ R L +++L + E R VLR LG+ + +++ GRVA
Sbjct: 818 VYTLCEKKAQIAIDIKSAKRELKKARTVLQMDELKCRKRVLRRLGFATSSDVIEMKGRVA 877
Query: 1082 CAMSS-HELLLTELMFDNALSTLRPEEIAALLSGLVCQSPGDAGDQLPNTLKQGIERVRA 1140
C +SS ELLLTE+MF+ + L E+ ALLS V Q +L L + +++
Sbjct: 878 CEISSADELLLTEMMFNGLFNDLSAEQATALLSCFVFQENSSEMPKLTEQLAGPLRQMQE 937
Query: 1141 VAKRIGEVQVACGLNQTVEEFVGELNFGLVEVVYEWARGMPFSELAGLSGTPEGLVVRCI 1200
AKRI +V L E ++ L++VVY WA G F+ + ++ EG ++RC+
Sbjct: 938 CAKRIAKVSAEAKLEIDEETYLSSFKPHLMDVVYTWATGATFAHICKMTDVFEGSIIRCM 997
Query: 1201 QRLAEMCRSLRGAARLVGEPVLGAKMETAATLLRRDIVFAASLY 1244
+RL E+ R + AA+ +G L K T ++RDIVFAASLY
Sbjct: 998 RRLEELLRQMCQAAKAIGNTELENKFAEGITKIKRDIVFAASLY 1041
>gi|130484567 HFM1 protein [Homo sapiens]
Length = 1435
Score = 114 bits (285), Expect = 6e-25
Identities = 113/428 (26%), Positives = 183/428 (42%), Gaps = 94/428 (21%)
Query: 330 VAAHTSAGKTVVAEYAIALAQKHMT------RTIYTSPIKALSNQKFRDFRNTFGDVGL- 382
+ A T +GKTVV E AI + + +Y +PIKAL +Q+F D++ FG +GL
Sbjct: 301 ICAPTGSGKTVVFELAITRLLMEVPLPWLNIKIVYMAPIKALCSQRFDDWKEKFGPIGLN 360
Query: 383 ---LTGDVQLHP-----EASCLIMTTEILRSMLYSGSD--VIRDLEWVIFDEVHYINDVE 432
LTGD + A ++ T E SM D +++ + + DEVH + D
Sbjct: 361 CKELTGDTVMDDLFEIQHAHIIMTTPEKWDSMTRKWRDNSLVQLVRLFLIDEVHIVKDEN 420
Query: 433 RGVVWEEVLIMLPDHVSI---------------ILLSATVPNALEFADWIGRLKRRQIYV 477
RG E V+ + S+ + +SAT+PNA + A+W+ +R + +
Sbjct: 421 RGPTLEVVVSRMKTVQSVSQTLKNTSTAIPMRFVAVSATIPNAEDIAEWLSDGERPAVCL 480
Query: 478 -ISTVTRPVPLEHYL--FTGNSSKTQGELFLLLDSRGAFHTKGYYAAVEAKKERMSKHAQ 534
+ RPV L+ + F +S++T+ + L L+ + A + Y
Sbjct: 481 KMDESHRPVKLQKVVLGFPCSSNQTEFKFDLTLNYKIASVIQMY---------------- 524
Query: 535 TFGAKQPTHQGGPAQDRGVYLSLLASLRTRAQLPVVVFTFSRGRCDEQASGLT--SLDLT 592
Q P +VF +R + AS L + +
Sbjct: 525 -----------------------------SDQKPTLVFCATRKGVQQAASVLVKDAKFIM 555
Query: 593 TSSEKSEIHLFLQRCLARLRGSDRQLPQVLHMSELLNRGLGVHHSGILPILKEIVEMLFS 652
T +K LQ+ +R S + ++L G HH+G+ +++VE F+
Sbjct: 556 TVEQKQR----LQKYAYSVRDSK--------LRDILKDGAAYHHAGMELSDRKVVEGAFT 603
Query: 653 RGLVKVLFATETFAMGVNMPARTVVFDSMRKHDGSTFRDLLPGEYVQMAGRAGRRGLDPT 712
G + VLF T T AMGVN+PA VV S + G F + + +QM GRAGR D T
Sbjct: 604 VGDLPVLFTTSTLAMGVNLPAHLVVIKSTMHYAGGLFEEYSETDILQMIGRAGRPQFDTT 663
Query: 713 GTVILLCK 720
T +++ +
Sbjct: 664 ATAVIMTR 671
>gi|40217847 activating signal cointegrator 1 complex subunit 3-like 1
[Homo sapiens]
Length = 2136
Score = 112 bits (280), Expect = 2e-24
Identities = 128/494 (25%), Positives = 214/494 (43%), Gaps = 82/494 (16%)
Query: 272 PEAPEPPSQEQWAIPVDATSPVGDFYRLIPQPAFQWAFEPDVFQKQAILHLERHDSVFVA 331
PE PP++ P+ ++ + + Q F + F P Q ++ D+VFV
Sbjct: 1292 PEKYPPPTELLDLQPLPVSALRNSAFESLYQDKFPF-FNPIQTQVFNTVY-NSDDNVFVG 1349
Query: 332 AHTSAGKTVVAEYAI--ALAQKHMTRTIYTSPIKALSNQKFRDFRNTFGD-----VGLLT 384
A T +GKT+ AE+AI L Q R +Y +P++AL+ Q + D+ F D V LLT
Sbjct: 1350 APTGSGKTICAEFAILRMLLQSSEGRCVYITPMEALAEQVYMDWYEKFQDRLNKKVVLLT 1409
Query: 385 G----DVQLHPEASCLIMTTE--ILRSMLYSGSDVIRDLEWVIFDEVHYINDVERGVVWE 438
G D++L + + +I T E + S + ++++ + DEVH I E G V E
Sbjct: 1410 GETSTDLKLLGKGNIIISTPEKWDILSRRWKQRKNVQNINLFVVDEVHLIGG-ENGPVLE 1468
Query: 439 EVL-------IMLPDHVSIILLSATVPNALEFADWIGRLKRRQIYVISTVTRPVPLEHYL 491
+ + + I+ LS+++ NA + A W+G + RPVPLE ++
Sbjct: 1469 VICSRMRYISSQIERPIRIVALSSSLSNAKDVAHWLG-CSATSTFNFHPNVRPVPLELHI 1527
Query: 492 FTGNSSKTQGELFLLLDSRGAFHTKGYYAAVEAKKERMSKHAQTFGAKQPTHQGGPAQDR 551
N S TQ L + K Y A+ +KH+
Sbjct: 1528 QGFNISHTQTRLLSM--------AKPVYHAI-------TKHS------------------ 1554
Query: 552 GVYLSLLASLRTRAQLPVVVFTFSRGRCDEQASGLTSLD-LTTSSEKSEIHLFLQRCLAR 610
+ PV+VF SR + + LT++D LTT + + FL
Sbjct: 1555 -------------PKKPVIVFVPSR-----KQTRLTAIDILTTCAADIQRQRFLHCTEKD 1596
Query: 611 LRGSDRQLPQVLHMSELLNRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVN 670
L +L LLN G+G H G+ P+ + +VE LFS G ++V+ A+ + G+N
Sbjct: 1597 LIPYLEKLSDSTLKETLLN-GVGYLHEGLSPMERRLVEQLFSSGAIQVVVASRSLCWGMN 1655
Query: 671 MPARTVVFDSMRKHDGS--TFRDLLPGEYVQMAGRAGRRGLDPTGTVILLCKGRVPEMAD 728
+ A V+ + ++G + D + +QM G A R D G +++C+G D
Sbjct: 1656 VAAHLVIIMDTQYYNGKIHAYVDYPIYDVLQMVGHANRPLQDDEGRCVIMCQG---SKKD 1712
Query: 729 LHRMMMGKPSQLQS 742
+ + +P ++S
Sbjct: 1713 FFKKFLYEPLPVES 1726
Score = 99.4 bits (246), Expect = 2e-20
Identities = 129/511 (25%), Positives = 213/511 (41%), Gaps = 100/511 (19%)
Query: 257 LEDLVLKEASTAVSTPEAPEPPSQ--------EQWAIPVDATSPVGDFYRLIPQPAF--- 305
LEDLV + S ++ P E+ +P P G +L+P
Sbjct: 411 LEDLVFTQGSHFMANKRCQLPDGSFRRQRKGYEEVHVPALKPKPFGSEEQLLPVEKLPKY 470
Query: 306 -QWAFE--PDVFQKQAILH---LERHDSVFVAAHTSAGKTVVAEYAIALA-QKHMT---- 354
Q FE + + Q+ L+ LE +++ + A T AGKT VA + KH+
Sbjct: 471 AQAGFEGFKTLNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDGT 530
Query: 355 ------RTIYTSPIKALSNQKFRDFRNTFGDVGL----LTGDVQLHPE----ASCLIMTT 400
+ IY +P+++L + F G+ LTGD QL E ++ T
Sbjct: 531 INVDDFKIIYIAPMRSLVQEMVGSFGKRLATYGITVAELTGDHQLCKEEISATQIIVCTP 590
Query: 401 EILRSMLYSGSD--VIRDLEWVIFDEVHYINDVERGVVWEEVLI-------MLPDHVSII 451
E + G + + + +I DE+H ++D +RG V E ++ M + V +I
Sbjct: 591 EKWDIITRKGGERTYTQLVRLIILDEIHLLHD-DRGPVLEALVARAIRNIEMTQEDVRLI 649
Query: 452 LLSATVPNALEFADWIGRLKRRQIYVISTVTRPVPLEHYLFTGNSSKTQGELFLLLDSRG 511
LSAT+PN + A ++ + ++ RPVPLE + G + K + F +++
Sbjct: 650 GLSATLPNYEDVATFLRVDPAKGLFYFDNSFRPVPLEQ-TYVGITEKKAIKRFQIMN--- 705
Query: 512 AFHTKGYYAAVEAKKERMSKHAQTFGAKQPTHQGGPAQDRGVYLSLLASLRTRAQLPVVV 571
E E++ +HA G Q V+V
Sbjct: 706 -----------EIVYEKIMEHA---GKNQ----------------------------VLV 723
Query: 572 FTFSRGRCDEQASGLTSLDLTTSSEKSEIHLFLQRCLARLRGSDRQLPQV--LHMSELLN 629
F SR + A + + L EK + LFL+ A + Q L + +LL
Sbjct: 724 FVHSRKETGKTARAIRDMCL----EKDTLGLFLREGSASTEVLRTEAEQCKNLELKDLLP 779
Query: 630 RGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVNMPARTVVFDSMRKH--DGS 687
G +HH+G+ + + +VE LF+ ++VL +T T A GVN+PA TV+ + + +
Sbjct: 780 YGFAIHHAGMTRVDRTLVEDLFADKHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKG 839
Query: 688 TFRDLLPGEYVQMAGRAGRRGLDPTGTVILL 718
+ +L + +QM GRAGR D G IL+
Sbjct: 840 RWTELGALDILQMLGRAGRPQYDTKGEGILI 870
>gi|169218225 PREDICTED: similar to U5 snRNP-specific 200kD protein,
partial [Homo sapiens]
Length = 1700
Score = 107 bits (268), Expect = 5e-23
Identities = 125/494 (25%), Positives = 211/494 (42%), Gaps = 82/494 (16%)
Query: 272 PEAPEPPSQEQWAIPVDATSPVGDFYRLIPQPAFQWAFEPDVFQKQAILHLERHDSVFVA 331
PE PP++ P+ ++ + + Q F + F P Q ++ D+VFV
Sbjct: 856 PEKYPPPTELLDLQPLPVSALRNSAFESLYQDKFPF-FNPIQTQVFNTVY-NSDDNVFVG 913
Query: 332 AHTSAGKTVVAEYAI--ALAQKHMTRTIYTSPIKALSNQKFRDFRNTFGD-----VGLLT 384
A T +GKT+ AE+AI L Q R +Y +P++ Q + D+ F D V LLT
Sbjct: 914 APTGSGKTICAEFAILRMLLQNSEGRCVYITPMRLWQEQVYMDWYEKFQDRLNKKVVLLT 973
Query: 385 G----DVQLHPEASCLIMTTE--ILRSMLYSGSDVIRDLEWVIFDEVHYINDVERGVVWE 438
G D++L + + +I T E + S + ++++ + DEVH I E G V E
Sbjct: 974 GETSTDLKLLGKGNIIISTPEKWDILSRRWKQRKNVQNINLFVVDEVHLIGG-ENGPVLE 1032
Query: 439 EVL-------IMLPDHVSIILLSATVPNALEFADWIGRLKRRQIYVISTVTRPVPLEHYL 491
+ + + I+ LS+++ NA + A W+G + RPVPLE ++
Sbjct: 1033 VICSRMRYISSQIERPIRIVALSSSLSNAKDVAHWLG-CSATSTFNFHPNVRPVPLELHI 1091
Query: 492 FTGNSSKTQGELFLLLDSRGAFHTKGYYAAVEAKKERMSKHAQTFGAKQPTHQGGPAQDR 551
N S TQ L + ++ FH ++KH+
Sbjct: 1092 QGFNISHTQTRLLSM--AKPVFHA-------------ITKHS------------------ 1118
Query: 552 GVYLSLLASLRTRAQLPVVVFTFSRGRCDEQASGLTSLD-LTTSSEKSEIHLFLQRCLAR 610
+ PV+VF SR + + LT++D LTT + + FL
Sbjct: 1119 -------------PKKPVIVFVPSR-----KQTRLTAIDILTTCAADIQRQRFLHCTEKD 1160
Query: 611 LRGSDRQLPQVLHMSELLNRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVN 670
L +L LLN G+G H G+ P+ + +VE LFS G ++V+ A+ + G+N
Sbjct: 1161 LIPYLEKLSDSTLKETLLN-GVGYLHEGLSPMERRLVEQLFSSGAIQVVVASRSLCWGMN 1219
Query: 671 MPARTVVFDSMRKHDGS--TFRDLLPGEYVQMAGRAGRRGLDPTGTVILLCKGRVPEMAD 728
+ A V+ ++G + D + +QM G A R D G +++C+G D
Sbjct: 1220 VAAHLVIIMDTLYYNGKIHAYVDYPIYDVLQMVGHANRPLQDDEGRCVIMCQG---SKKD 1276
Query: 729 LHRMMMGKPSQLQS 742
+ + +P ++S
Sbjct: 1277 FFKKFLYEPLPVES 1290
Score = 96.7 bits (239), Expect = 1e-19
Identities = 110/429 (25%), Positives = 183/429 (42%), Gaps = 83/429 (19%)
Query: 322 LERHDSVFVAAHTSAGKTVVAEYAIALA-QKHMT----------RTIYTSPIKALSNQKF 370
LE +++ + A T AGKT VA + KH+ + IY +P+++L +
Sbjct: 57 LETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFKIIYIAPMRSLVQEMV 116
Query: 371 RDFRNTFGDVGL----LTGDVQLHPE----ASCLIMTTEILRSMLYSGSD--VIRDLEWV 420
F G+ LTGD QL E ++ T E + G + + + +
Sbjct: 117 GSFGKRLATYGITVAELTGDHQLCKEEISATQIIVCTPEKWDIITRKGGERTYTQLVRLI 176
Query: 421 IFDEVHYINDVERGVVWEEVLI-------MLPDHVSIILLSATVPNALEFADWIGRLKRR 473
+ DE+H ++D +RG V E ++ M + V +I LSAT+PN + A ++ +
Sbjct: 177 VLDEIHLLHD-DRGPVLEALVARAIRNIEMTQEDVRLIGLSATLPNYEDVATFLRVDPAK 235
Query: 474 QIYVISTVTRPVPLEHYLFTGNSSKTQGELFLLLDSRGAFHTKGYYAAVEAKKERMSKHA 533
++ RPVPLE + G + K + F +++ E E++ +HA
Sbjct: 236 GLFYFDNSFRPVPLEQ-TYVGITEKKAIKRFQIMN--------------EIVYEKIMEHA 280
Query: 534 QTFGAKQPTHQGGPAQDRGVYLSLLASLRTRAQLPVVVFTFSRGRCDEQASGLTSLDLTT 593
G Q V+VF SR + A + + L
Sbjct: 281 ---GKNQ----------------------------VLVFVHSRKETGKTARAIRDMCL-- 307
Query: 594 SSEKSEIHLFLQRCLARLRGSDRQLPQV--LHMSELLNRGLGVHHSGILPILKEIVEMLF 651
EK + LFL+ A + Q L + +LL G +HH+G+ + + +VE LF
Sbjct: 308 --EKDTLGLFLREGSASTEVLRTEAEQCKNLELKDLLPYGFAIHHAGMTRVDRTLVEDLF 365
Query: 652 SRGLVKVLFATETFAMGVNMPARTVVFDSMRKH--DGSTFRDLLPGEYVQMAGRAGRRGL 709
++VL +T T A GVN+PA TV+ + + + + +L + +QM GRAGR
Sbjct: 366 GDKHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRAGRPQY 425
Query: 710 DPTGTVILL 718
D G IL+
Sbjct: 426 DTKGEGILI 434
>gi|76880486 activating signal cointegrator 1 complex subunit 3
isoform a [Homo sapiens]
Length = 2202
Score = 104 bits (259), Expect = 6e-22
Identities = 112/419 (26%), Positives = 186/419 (44%), Gaps = 85/419 (20%)
Query: 327 SVFVAAHTSAGKTVVAEYAI-ALAQKHMT-RTIYTSPIKALSNQKFRDFRNTFGD----- 379
+V + A T +GKTV AE AI + K+ T + +Y +P+KAL ++ D++ +
Sbjct: 1344 NVLLGAPTGSGKTVAAELAIFRVFNKYPTSKAVYIAPLKALVRERMDDWKVRIEEKLGKK 1403
Query: 380 ----VGLLTGDVQLHPEASCLIMTTE----ILRSMLYSGSDVIRDLEWVIFDEVHYINDV 431
G +T D++ +A ++ T E + RS + + ++ + +I DE+H + +
Sbjct: 1404 VIELTGDVTPDMKSIAKADLIVTTPEKWDGVSRS--WQNRNYVQQVTILIIDEIHLLGE- 1460
Query: 432 ERGVVWEEVLI---MLPDH----VSIILLSATVPNALEFADWIGRLKRRQIYVISTVTRP 484
ERG V E ++ + H V I+ LS + NA + ADW+ +K+ ++ RP
Sbjct: 1461 ERGPVLEVIVSRTNFISSHTEKPVRIVGLSTALANARDLADWLN-IKQMGLFNFRPSVRP 1519
Query: 485 VPLEHYLFTGNSSKTQGELFLLLDSRGAFHTKGYYAAVEAKKERMSKHAQTFGAKQPTHQ 544
VPLE ++ QG F + Y + + + A Q
Sbjct: 1520 VPLEVHI--------QG-----------FPGQHYCPRMASMNKP---------AFQAIRS 1551
Query: 545 GGPAQDRGVYLSLLASLRTRAQLPVVVFTFSRGRCDEQASGLTSLDLTTSSEKSEIHLF- 603
PA+ PV++F SR + A L + T K +++
Sbjct: 1552 HSPAK------------------PVLIFVSSRRQTRLTALELIAFLATEEDPKQWLNMDE 1593
Query: 604 --LQRCLARLRGSDRQLPQVLHMSELLNRGLGVHHSGILPILKEIVEMLFSRGLVKVLFA 661
++ +A +R S+ +L L G+G+HH+G+ ++ VE LF V+VL A
Sbjct: 1594 REMENIIATVRDSNLKLT--------LAFGIGMHHAGLHERDRKTVEELFVNCKVQVLIA 1645
Query: 662 TETFAMGVNMPARTVVFDSMRKHDGSTFR--DLLPGEYVQMAGRAGRRGLDPTGTVILL 718
T T A GVN PA V+ +DG T R D + +QM GRAGR D G ++L
Sbjct: 1646 TSTLAWGVNFPAHLVIIKGTEYYDGKTRRYVDFPITDVLQMMGRAGRPQFDDQGKAVIL 1704
Score = 62.8 bits (151), Expect = 2e-09
Identities = 37/95 (38%), Positives = 53/95 (55%), Gaps = 2/95 (2%)
Query: 626 ELLNRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVNMPARTVVFDSMRKHD 685
EL G +HH+G+L + +VE LFS G +KVL T T A GVN+PA V+ + +
Sbjct: 773 ELFPDGFSIHHAGMLRQDRNLVENLFSNGHIKVLVCTATLAWGVNLPAHAVIIKGTQIYA 832
Query: 686 G--STFRDLLPGEYVQMAGRAGRRGLDPTGTVILL 718
+F DL + +Q+ GRAGR D G I++
Sbjct: 833 AKRGSFVDLGILDVMQIFGRAGRPQFDKFGEGIII 867
Score = 48.9 bits (115), Expect = 3e-05
Identities = 50/194 (25%), Positives = 88/194 (45%), Gaps = 35/194 (18%)
Query: 325 HDSVFVAAHTSAGKTVVAEYAI----------ALAQKHMTRTIYTSPIKALSNQKFRDFR 374
++++ + A T AGKT +A + + +K+ + +Y +P+KAL+ + F
Sbjct: 492 NENMLICAPTGAGKTNIAMLTVLHEIRQHFQQGVIKKNEFKIVYVAPMKALAAEMTDYFS 551
Query: 375 NTFGDVGL----LTGDVQLHPEASCLIMTTEILRSMLYSGSDVIRD----------LEWV 420
+G+ LTGD+QL I+ T++L + V R + +
Sbjct: 552 RRLEPLGIIVKELTGDMQLSKSE---ILRTQMLVTTPEKWDVVTRKSVGDVALSQIVRLL 608
Query: 421 IFDEVHYINDVERGVVWEEVLIMLPDHVS-------IILLSATVPNALEFADWIGRLKRR 473
I DEVH +++ +RG V E ++ V I+ LSAT+PN L+ A ++
Sbjct: 609 ILDEVHLLHE-DRGPVLESIVARTLRQVESTQSMIRILGLSATLPNYLDVATFLHVNPYI 667
Query: 474 QIYVISTVTRPVPL 487
++ RPVPL
Sbjct: 668 GLFFFDGRFRPVPL 681
>gi|139394648 DNA polymerase theta [Homo sapiens]
Length = 2590
Score = 89.7 bits (221), Expect = 2e-17
Identities = 123/502 (24%), Positives = 208/502 (41%), Gaps = 96/502 (19%)
Query: 262 LKEASTAVSTPEAPEPPSQE----QWAIPVDATSPVGDFYRLIPQPAFQWAFEPDVFQKQ 317
LK A+ P P+ + W +P + + ++ + F+W E + +
Sbjct: 49 LKAAAAGECKPTVPDYERDKLLLANWGLP---KAVLEKYHSFGVKKMFEWQAECLLLGQV 105
Query: 318 AILHLERHDSVFVAAHTSAGKTVVAEYAIALAQKHMTR-TIYTSPIKALSNQKFRDFRNT 376
LE + V+ +A TSAGKT+VAE I M + ++ P +++ +K ++
Sbjct: 106 ----LEGKNLVY-SAPTSAGKTLVAELLILKRVLEMRKKALFILPFVSVAKEKKYYLQSL 160
Query: 377 FGDVGLLTGDVQLHPEASCLIMTTEILRSMLYSGSDVIRDL---------EWVIFDEVHY 427
F +VG+ S + +I + + +I L V+ DE+H
Sbjct: 161 FQEVGIKVDGYMGSTSPSRHFSSLDIAVCTIERANGLINRLIEENKMDLLGMVVVDELHM 220
Query: 428 INDVERGVVWEEVLIM------------------LPDHVSIILLSATVPNALEFADWIGR 469
+ D RG + E +L L + V I+ +SAT+PN A W+
Sbjct: 221 LGDSHRGYLLELLLTKICYITRKSASCQADLASSLSNAVQIVGMSATLPNLELVASWLNA 280
Query: 470 LKRRQIYVISTVTRPVPLEHYLFTGNSSKTQGELFLLLDSRGAFHTKGYYAAVEAKKERM 529
++Y T RPVPL + GNS Y ++++ +E
Sbjct: 281 ----ELY--HTDFRPVPLLESVKVGNSI--------------------YDSSMKLVREF- 313
Query: 530 SKHAQTFGAKQPTHQGGPAQDRGVYLSLLASLRTRAQLPVVVFTFSRGRCDEQASGLT-- 587
+P Q +D V L + V++F S+ C++ A +
Sbjct: 314 ----------EPMLQVKGDEDHVVSLCYETICDNHS---VLLFCPSKKWCEKLADIIARE 360
Query: 588 -------SLDLTTSSEKSEIHLFLQRCLARLRGSDRQLPQVLH--MSELLNRGLGVHHSG 638
+ L SE + + Q+ L + R+LP L + + + G+ HH+G
Sbjct: 361 FYNLHHQAEGLVKPSECPPV-ILEQKELLEVMDQLRRLPSGLDSVLQKTVPWGVAFHHAG 419
Query: 639 ILPILKEIVEMLFSRGLVKVLFATETFAMGVNMPARTVVFDSMRKHDGSTFRDLLPGEYV 698
+ ++I+E F +GL++VL AT T + GVN+PAR V+ + G D+L Y
Sbjct: 420 LTFEERDIIEGAFRQGLIRVLAATSTLSSGVNLPARRVIIRT--PIFGGRPLDIL--TYK 475
Query: 699 QMAGRAGRRGLDPTGTVILLCK 720
QM GRAGR+G+D G IL+CK
Sbjct: 476 QMVGRAGRKGVDTVGESILICK 497
>gi|149274648 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like [Homo
sapiens]
Length = 1706
Score = 88.6 bits (218), Expect = 3e-17
Identities = 61/178 (34%), Positives = 95/178 (53%), Gaps = 26/178 (14%)
Query: 615 DRQLPQVL------HMSELLNRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMG 668
+R LP+V + L RG+G HHS + KE VE+LF +GL++V+ ATET A+G
Sbjct: 1222 ERVLPRVRFTRHGKELKALAQRGIGYHHSSMYFKEKEFVEILFVKGLIRVVTATETLALG 1281
Query: 669 VNMPARTVVFDSMRKHDGSTFRDLLPGEYVQMAGRAGRRGLDPTGTVILLCKGRVPEMAD 728
++MP ++VVF S + D L Y QM+GRAGRRG D G V +P +
Sbjct: 1282 IHMPCKSVVF-----AQDSVYLDAL--NYRQMSGRAGRRGQDLLGNVYFF---DIP-LPK 1330
Query: 729 LHRMMMGKPSQLQSQFRLTYTMILNLLRVDA---------LRVEDMMKRSFSEFPSRK 777
+ R++ +L+ QF L+ T++L L+ + + +V ++K S F R+
Sbjct: 1331 IKRLLASSVPELRGQFPLSITLVLRLMLLASKGDDPEDAKAKVLSVLKHSLLSFKRRR 1388
Score = 59.7 bits (143), Expect = 2e-08
Identities = 48/179 (26%), Positives = 84/179 (46%), Gaps = 19/179 (10%)
Query: 309 FEPDVFQKQAILHLERHDSVFVAAHTSAGKTVVAEYAI--ALAQKHMTRTIYTSPIKALS 366
F P+ +Q++ + +++++S + A TS+GKT + Y + L + + +Y +P K+L
Sbjct: 742 FIPNAWQQELLDVVDKNESAVIVAPTSSGKTYASYYCMEKVLRESDVGVVVYVAPAKSLV 801
Query: 367 NQKFRDFRNTFGDV--------GLLTGDVQLHPEASCLIMTT-----EILRSMLYSGSDV 413
Q N F G T D H +C ++ T EIL + V
Sbjct: 802 GQVAATVENRFTKTLPAGRTLCGAFTRDY-CHNVLNCQVLITVPECFEILLLAPHRQKWV 860
Query: 414 IRDLEWVIFDEVHYINDVERGVVWEEVLIMLPDHVSIILLSATVPNALEFADWIGRLKR 472
R + +VIFDEVHY+ WE +L+++ ++LSAT+ N W+ +K+
Sbjct: 861 ER-IRYVIFDEVHYLGREVGAKFWELLLVII--RCPFLVLSATINNPNLLTKWLQSVKQ 916
>gi|222831595 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 [Homo sapiens]
Length = 1712
Score = 79.7 bits (195), Expect = 2e-14
Identities = 56/166 (33%), Positives = 93/166 (56%), Gaps = 15/166 (9%)
Query: 590 DLTTSSEKSEIHLFLQRCLARLRGSDRQLPQVLHMSELLNRGLGVHHSGILPILKEIVEM 649
D T + +K+ LQ+ R++ +R+ ++ ++E RG+G HHS + K++VE+
Sbjct: 1223 DCTYADQKAVDTETLQKVFGRVK-FERKGEELKALAE---RGIGYHHSAMSFKEKQLVEI 1278
Query: 650 LFSRGLVKVLFATETFAMGVNMPARTVVFDSMRKHDGSTFRDLLPGEYVQMAGRAGRRGL 709
LF +G ++V+ AT T A+GVNMP ++VVF S + D L Y QM+GRAGRRG
Sbjct: 1279 LFRKGYLRVVTATGTLALGVNMPCKSVVF-----AQNSVYLDAL--NYRQMSGRAGRRGQ 1331
Query: 710 DPTGTVILLCKGRVPEMADLHRMMMGKPSQLQSQFRLTYTMILNLL 755
D G V +P + +++ +L+ F L+ T++L L+
Sbjct: 1332 DLMGDVYFF---DIP-FPKIGKLIKSNVPELRGHFPLSITLVLRLM 1373
Score = 70.9 bits (172), Expect = 7e-12
Identities = 53/186 (28%), Positives = 92/186 (49%), Gaps = 20/186 (10%)
Query: 301 PQPAFQWAFEPDVFQKQAILHLERHDSVFVAAHTSAGKTVVAEYAIALAQKHMTR--TIY 358
P P Q F PD +Q++ + +++++S + A TS+GKT + Y + K +Y
Sbjct: 755 PDPRVQ-DFIPDTWQRELLDVVDKNESAVIVAPTSSGKTYASYYCMEKVLKESDDGVVVY 813
Query: 359 TSPIKALSNQKFRDFRNTF------GDV--GLLTGDVQLHPEASCLIMTT-----EILRS 405
+P KAL NQ +N F G+V G+ T + + H +C ++ T EIL
Sbjct: 814 VAPTKALVNQVAATVQNRFTKNLPSGEVLCGVFTREYR-HDALNCQVLITVPACFEILLL 872
Query: 406 MLYSGSDVIRDLEWVIFDEVHYINDVERGVVWEEVLIMLPDHVSIILLSATVPNALEFAD 465
+ + ++ + +VIFDEVH + +WE +L+M+ + LSAT+ N +
Sbjct: 873 APHR-QNWVKKIRYVIFDEVHCLGGEIGAEIWEHLLVMI--RCPFLALSATISNPEHLTE 929
Query: 466 WIGRLK 471
W+ +K
Sbjct: 930 WLQSVK 935
>gi|110556640 DNA helicase HEL308 [Homo sapiens]
Length = 1101
Score = 64.7 bits (156), Expect = 5e-10
Identities = 113/496 (22%), Positives = 198/496 (39%), Gaps = 87/496 (17%)
Query: 252 ARASSLEDLVL-KEASTAVSTPEAPEPPSQEQWAIPVDATSPVGDFYRLIP--QPAFQWA 308
+R+ L+D +L +E + A T E+ +++P S V D Y + ++W
Sbjct: 285 SRSKQLKDTLLSEEINVAKKTVESSSNDLGPFYSLP----SKVRDLYAQFKGIEKLYEWQ 340
Query: 309 FEPDVFQKQAILHLERHDSVFVAAHTSAGKTVVAEYAIALAQKHMT---RTIYTSPIKAL 365
++ ++ + TS GKT+VAE I + Q+ + + P A+
Sbjct: 341 HTCLTLNS-----VQERKNLIYSLPTSGGKTLVAE--ILMLQELLCCRKDVLMILPYVAI 393
Query: 366 SNQKFRDFRNTFGDVGLLTGD----------VQLHPEASCLIMTTE----ILRSMLYSGS 411
+K + ++G + + + S I T E ++ S++ +G
Sbjct: 394 VQEKISGLSSFGIELGFFVEEYAGSKGRFPPTKRREKKSLYIATIEKGHSLVNSLIETGR 453
Query: 412 DVIRDLEWVIFDEVHYINDVERGVVWEEVLIML---PDHVSIILLSATVPNALEFADWIG 468
I L V+ DE+H I + RG E L + II +SAT+ N + ++
Sbjct: 454 --IDSLGLVVVDELHMIGEGSRGATLEMTLAKILYTSKTTQIIGMSATLNNVEDLQKFL- 510
Query: 469 RLKRRQIYVISTVTRPVPLEHYLFTGNSSKTQGELFLLLDSRGAFHTKGYYAAVEAKKER 528
Q ++ RPV L+ YL + T E+ ++ F Y
Sbjct: 511 -----QAEYYTSQFRPVELKEYL---KINDTIYEVDSKAENGMTFSRLLNY--------- 553
Query: 529 MSKHAQTFGAKQPTHQGGPAQDRGVYLSLLASLRTRA--QLPVVVFTFSRGRCDEQASGL 586
K++ T P H L +L T +VF S+ C+ A +
Sbjct: 554 --KYSDTLKKMDPDH--------------LVALVTEVIPNYSCLVFCPSKKNCENVAEMI 597
Query: 587 TSLDLTTSSEKSEIHLFLQRC--LARLR--GSDRQLPQVLHMSELLNRGLGVHHSGILPI 642
S++ H ++C + L+ G+ P + + G+ HHSG+
Sbjct: 598 CKF----LSKEYLKHKEKEKCEVIKNLKNIGNGNLCPV---LKRTIPFGVAYHHSGLTSD 650
Query: 643 LKEIVEMLFSRGLVKVLFATETFAMGVNMPARTVVFDSMRKHDGSTFRDLLPGEYVQMAG 702
++++E +S G++ + T T A GVN+PAR V+ + + F L +Y QM G
Sbjct: 651 ERKLLEEAYSTGVLCLFTCTSTLAAGVNLPARRVILRA--PYVAKEF--LKRNQYKQMIG 706
Query: 703 RAGRRGLDPTGTVILL 718
RAGR G+D G IL+
Sbjct: 707 RAGRAGIDTIGESILI 722
>gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2
[Homo sapiens]
Length = 881
Score = 39.3 bits (90), Expect = 0.024
Identities = 44/173 (25%), Positives = 73/173 (42%), Gaps = 21/173 (12%)
Query: 311 PDVFQKQAILHLERHDSVFVAAHTSAGKTVVAEYAIALAQKHMT-------RTIYTSPIK 363
P Q++ I + V A T +GKT A + + + ++ T R + SP +
Sbjct: 119 PTPIQRKTIPVILDGKDVVAMARTGSGKT--ACFLLPMFERLKTHSAQTGARALILSPTR 176
Query: 364 ALSNQKFRDFRNTFGDVGLLT-----GD------VQLHPEASCLIMTTEILRSMLYSGSD 412
L+ Q + + GL T GD LH +I T L + S
Sbjct: 177 ELALQTLKFTKELGKFTGLKTALILGGDRMEDQFAALHENPDIIIATPGRLVHVAVEMSL 236
Query: 413 VIRDLEWVIFDEVHYINDVERGVVWEEVLIMLPDHVSIILLSATVPNAL-EFA 464
++ +E+V+FDE + ++ +E++ LP +L SAT+P L EFA
Sbjct: 237 KLQSVEYVVFDEADRLFEMGFAEQLQEIIARLPGGHQTVLFSATLPKLLVEFA 289
>gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1
[Homo sapiens]
Length = 882
Score = 39.3 bits (90), Expect = 0.024
Identities = 44/173 (25%), Positives = 73/173 (42%), Gaps = 21/173 (12%)
Query: 311 PDVFQKQAILHLERHDSVFVAAHTSAGKTVVAEYAIALAQKHMT-------RTIYTSPIK 363
P Q++ I + V A T +GKT A + + + ++ T R + SP +
Sbjct: 119 PTPIQRKTIPVILDGKDVVAMARTGSGKT--ACFLLPMFERLKTHSAQTGARALILSPTR 176
Query: 364 ALSNQKFRDFRNTFGDVGLLT-----GD------VQLHPEASCLIMTTEILRSMLYSGSD 412
L+ Q + + GL T GD LH +I T L + S
Sbjct: 177 ELALQTLKFTKELGKFTGLKTALILGGDRMEDQFAALHENPDIIIATPGRLVHVAVEMSL 236
Query: 413 VIRDLEWVIFDEVHYINDVERGVVWEEVLIMLPDHVSIILLSATVPNAL-EFA 464
++ +E+V+FDE + ++ +E++ LP +L SAT+P L EFA
Sbjct: 237 KLQSVEYVVFDEADRLFEMGFAEQLQEIIARLPGGHQTVLFSATLPKLLVEFA 289
>gi|150418009 transforming, acidic coiled-coil containing protein 2
isoform a [Homo sapiens]
Length = 2948
Score = 38.5 bits (88), Expect = 0.040
Identities = 26/70 (37%), Positives = 33/70 (47%), Gaps = 6/70 (8%)
Query: 229 EAVGQPGGPRGDTVSASPCSAP-----LARASSLEDLV-LKEASTAVSTPEAPEPPSQEQ 282
E + P P GD V AS S P L+R+S E+ E++T V P AP PP E
Sbjct: 1916 EHIVSPSAPAGDRVEASTPSCPDPAKDLSRSSDSEEAFETPESTTPVKAPPAPPPPPPEV 1975
Query: 283 WAIPVDATSP 292
P +T P
Sbjct: 1976 IPEPEVSTQP 1985
>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 38.1 bits (87), Expect = 0.053
Identities = 77/338 (22%), Positives = 109/338 (32%), Gaps = 62/338 (18%)
Query: 7 LVLPPPDPLDLPLRAVELGCTGHWELLNLP--GAPESSLPHGLPPCAPDLQQEAEQLFLS 64
L++PPP P P G + ++ P G+P S P PP P L + ++
Sbjct: 137 LLIPPPPPGPAP---------GPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMA 187
Query: 65 SP------AWLPLHGVEHSA----RKWQRKTDPWSLLAVLGAPVPSDLQ---AQRH---- 107
P A P H + + + P + LA PVP+ A H
Sbjct: 188 PPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGT 247
Query: 108 ---PTTGQILGYKEVLLENTNLSATTSLSLRRPPGPASQSLWGNPTQYPFWPGGMDEPTI 164
P G +V L AT + R P P +L NP + +P P
Sbjct: 248 RLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPP 307
Query: 165 TDLNTR----EEAEEEIDFEK-------DLLTIPPGF--KKGMDFAPKDCPTP-APGLLS 210
T + T +EA+E E+ L +PP F + P P P PG L
Sbjct: 308 TPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELK 367
Query: 211 LSCMLEPLDLGGGDEDENEAVG----------------QPGGPRGDTVSASPCSAPLARA 254
+ P LG +E G P P PC+ A
Sbjct: 368 ATAPASP-RLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHP 426
Query: 255 SSLEDLVLKEASTAVSTPEAPEPPSQEQWAIPVDATSP 292
+ K +S A+ P P + PVD P
Sbjct: 427 PAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDP 464
Score = 32.3 bits (72), Expect = 2.9
Identities = 31/91 (34%), Positives = 35/91 (38%), Gaps = 10/91 (10%)
Query: 168 NTREEAEEEIDFEKDLLTIPPGFKKGMDFAPKDCPTPAPGLLSLSCMLEPLDLGGGDEDE 227
N REE EEE +FE ++ PP F D PAP L L P D +
Sbjct: 972 NKREEEEEEFNFE--VIPPPPEFS-------NDPEPPAPALQYLGRQSSPPRNNYSDLRQ 1022
Query: 228 NEAVGQPGGPRGDTVSASPCSAPLARASSLE 258
G PG P S P A A A LE
Sbjct: 1023 LPNAG-PGAPPALGFSRFPAGARYAGAGGLE 1052
>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 38.1 bits (87), Expect = 0.053
Identities = 77/338 (22%), Positives = 109/338 (32%), Gaps = 62/338 (18%)
Query: 7 LVLPPPDPLDLPLRAVELGCTGHWELLNLP--GAPESSLPHGLPPCAPDLQQEAEQLFLS 64
L++PPP P P G + ++ P G+P S P PP P L + ++
Sbjct: 137 LLIPPPPPGPAP---------GPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMA 187
Query: 65 SP------AWLPLHGVEHSA----RKWQRKTDPWSLLAVLGAPVPSDLQ---AQRH---- 107
P A P H + + + P + LA PVP+ A H
Sbjct: 188 PPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGT 247
Query: 108 ---PTTGQILGYKEVLLENTNLSATTSLSLRRPPGPASQSLWGNPTQYPFWPGGMDEPTI 164
P G +V L AT + R P P +L NP + +P P
Sbjct: 248 RLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPP 307
Query: 165 TDLNTR----EEAEEEIDFEK-------DLLTIPPGF--KKGMDFAPKDCPTP-APGLLS 210
T + T +EA+E E+ L +PP F + P P P PG L
Sbjct: 308 TPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELK 367
Query: 211 LSCMLEPLDLGGGDEDENEAVG----------------QPGGPRGDTVSASPCSAPLARA 254
+ P LG +E G P P PC+ A
Sbjct: 368 ATAPASP-RLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHP 426
Query: 255 SSLEDLVLKEASTAVSTPEAPEPPSQEQWAIPVDATSP 292
+ K +S A+ P P + PVD P
Sbjct: 427 PAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDP 464
Score = 32.3 bits (72), Expect = 2.9
Identities = 31/91 (34%), Positives = 35/91 (38%), Gaps = 10/91 (10%)
Query: 168 NTREEAEEEIDFEKDLLTIPPGFKKGMDFAPKDCPTPAPGLLSLSCMLEPLDLGGGDEDE 227
N REE EEE +FE ++ PP F D PAP L L P D +
Sbjct: 972 NKREEEEEEFNFE--VIPPPPEFS-------NDPEPPAPALQYLGRQSSPPRNNYSDLRQ 1022
Query: 228 NEAVGQPGGPRGDTVSASPCSAPLARASSLE 258
G PG P S P A A A LE
Sbjct: 1023 LPNAG-PGAPPALGFSRFPAGARYAGAGGLE 1052
>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo
sapiens]
Length = 1188
Score = 38.1 bits (87), Expect = 0.053
Identities = 77/338 (22%), Positives = 109/338 (32%), Gaps = 62/338 (18%)
Query: 7 LVLPPPDPLDLPLRAVELGCTGHWELLNLP--GAPESSLPHGLPPCAPDLQQEAEQLFLS 64
L++PPP P P G + ++ P G+P S P PP P L + ++
Sbjct: 137 LLIPPPPPGPAP---------GPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMA 187
Query: 65 SP------AWLPLHGVEHSA----RKWQRKTDPWSLLAVLGAPVPSDLQ---AQRH---- 107
P A P H + + + P + LA PVP+ A H
Sbjct: 188 PPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGT 247
Query: 108 ---PTTGQILGYKEVLLENTNLSATTSLSLRRPPGPASQSLWGNPTQYPFWPGGMDEPTI 164
P G +V L AT + R P P +L NP + +P P
Sbjct: 248 RLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPP 307
Query: 165 TDLNTR----EEAEEEIDFEK-------DLLTIPPGF--KKGMDFAPKDCPTP-APGLLS 210
T + T +EA+E E+ L +PP F + P P P PG L
Sbjct: 308 TPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELK 367
Query: 211 LSCMLEPLDLGGGDEDENEAVG----------------QPGGPRGDTVSASPCSAPLARA 254
+ P LG +E G P P PC+ A
Sbjct: 368 ATAPASP-RLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHP 426
Query: 255 SSLEDLVLKEASTAVSTPEAPEPPSQEQWAIPVDATSP 292
+ K +S A+ P P + PVD P
Sbjct: 427 PAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDP 464
Score = 32.3 bits (72), Expect = 2.9
Identities = 31/91 (34%), Positives = 35/91 (38%), Gaps = 10/91 (10%)
Query: 168 NTREEAEEEIDFEKDLLTIPPGFKKGMDFAPKDCPTPAPGLLSLSCMLEPLDLGGGDEDE 227
N REE EEE +FE ++ PP F D PAP L L P D +
Sbjct: 972 NKREEEEEEFNFE--VIPPPPEFS-------NDPEPPAPALQYLGRQSSPPRNNYSDLRQ 1022
Query: 228 NEAVGQPGGPRGDTVSASPCSAPLARASSLE 258
G PG P S P A A A LE
Sbjct: 1023 LPNAG-PGAPPALGFSRFPAGARYAGAGGLE 1052
>gi|83367077 mucin 16 [Homo sapiens]
Length = 14507
Score = 37.4 bits (85), Expect = 0.090
Identities = 22/64 (34%), Positives = 29/64 (45%)
Query: 232 GQPGGPRGDTVSASPCSAPLARASSLEDLVLKEASTAVSTPEAPEPPSQEQWAIPVDATS 291
G P T S S+P R SS E KEAST T E P E++ +P + ++
Sbjct: 111 GTPSRNYPATSMVSGLSSPRTRTSSTEGNFTKEASTYTLTVETTSGPVTEKYTVPTETST 170
Query: 292 PVGD 295
GD
Sbjct: 171 TEGD 174
>gi|14591902 RecQ protein-like [Homo sapiens]
Length = 649
Score = 37.4 bits (85), Expect = 0.090
Identities = 29/94 (30%), Positives = 42/94 (44%), Gaps = 10/94 (10%)
Query: 614 SDRQLPQVLHMSELLNRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVNMP- 672
S + QV + L G +H+ + P K V +S ++V+ AT F MG++ P
Sbjct: 323 SQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKWSANEIQVVVATVAFGMGIDKPD 382
Query: 673 ARTVVFDSMRKHDGSTFRDLLPGEYVQMAGRAGR 706
R V+ SM K Y Q +GRAGR
Sbjct: 383 VRFVIHHSMSKS---------MENYYQESGRAGR 407
>gi|14591904 RecQ protein-like [Homo sapiens]
Length = 649
Score = 37.4 bits (85), Expect = 0.090
Identities = 29/94 (30%), Positives = 42/94 (44%), Gaps = 10/94 (10%)
Query: 614 SDRQLPQVLHMSELLNRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVNMP- 672
S + QV + L G +H+ + P K V +S ++V+ AT F MG++ P
Sbjct: 323 SQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKWSANEIQVVVATVAFGMGIDKPD 382
Query: 673 ARTVVFDSMRKHDGSTFRDLLPGEYVQMAGRAGR 706
R V+ SM K Y Q +GRAGR
Sbjct: 383 VRFVIHHSMSKS---------MENYYQESGRAGR 407
>gi|38570099 glutamine-rich 1 [Homo sapiens]
Length = 776
Score = 36.6 bits (83), Expect = 0.15
Identities = 33/149 (22%), Positives = 56/149 (37%), Gaps = 20/149 (13%)
Query: 241 TVSASPCSAPLARASSLEDLVLKEASTAVSTPEAPEPPSQEQWAIPVDATSPVGDFYRLI 300
TV A P + S DL+ +++ S P+ E W IPV + P GD
Sbjct: 267 TVLAIPQGQQQSYVSLRPDLLTVDSAHLYSATGTITSPTGETWTIPVYSAQPRGD----- 321
Query: 301 PQPAFQWAFEPDVFQKQAILHLERHDSVFVAAHTSAGKTVVAEYAIALAQKHMTRTIYTS 360
Q+Q+I H+ + A H S T +A + ++ M T TS
Sbjct: 322 -------------PQQQSITHIAIPQEAYNAVHVSGSPTALAAVKLEDDKEKMVGT--TS 366
Query: 361 PIKALSNQKFRDFRNTFGDVGLLTGDVQL 389
+K + + N+ + G++ +
Sbjct: 367 VVKNSHEEVVQTLANSLFPAQFMNGNIHI 395
>gi|38570097 glutamine-rich 1 [Homo sapiens]
Length = 776
Score = 36.6 bits (83), Expect = 0.15
Identities = 33/149 (22%), Positives = 56/149 (37%), Gaps = 20/149 (13%)
Query: 241 TVSASPCSAPLARASSLEDLVLKEASTAVSTPEAPEPPSQEQWAIPVDATSPVGDFYRLI 300
TV A P + S DL+ +++ S P+ E W IPV + P GD
Sbjct: 267 TVLAIPQGQQQSYVSLRPDLLTVDSAHLYSATGTITSPTGETWTIPVYSAQPRGD----- 321
Query: 301 PQPAFQWAFEPDVFQKQAILHLERHDSVFVAAHTSAGKTVVAEYAIALAQKHMTRTIYTS 360
Q+Q+I H+ + A H S T +A + ++ M T TS
Sbjct: 322 -------------PQQQSITHIAIPQEAYNAVHVSGSPTALAAVKLEDDKEKMVGT--TS 366
Query: 361 PIKALSNQKFRDFRNTFGDVGLLTGDVQL 389
+K + + N+ + G++ +
Sbjct: 367 VVKNSHEEVVQTLANSLFPAQFMNGNIHI 395
>gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens]
Length = 2303
Score = 36.2 bits (82), Expect = 0.20
Identities = 42/146 (28%), Positives = 55/146 (37%), Gaps = 17/146 (11%)
Query: 14 PLDLPLRAVELGCTGHWELLNLPGAPESSLPHGLPPCAPDLQQEAEQLFLSSPAWLPLHG 73
P LP+RA +LP + P G P AP A + P PL
Sbjct: 2081 PSRLPVRAPAARPETVKRYASLPHISVARRPDGAVPAAPASADAARRSSDGEPR--PLPR 2138
Query: 74 VEHSARKWQRKTD-----------PWSLLAVLGAPVPSDLQAQRHP--TTGQILGYKEVL 120
V W+R D P + L + G+ P D A P T+ ++ +EV
Sbjct: 2139 VAAPGTTWRRIRDEDVPHILRSTLPATALPLRGS-TPEDAPAGPPPRKTSDAVVQTEEVA 2197
Query: 121 LENTNLSATTSLSLRRPPG-PASQSL 145
TN S + SL R PPG PA L
Sbjct: 2198 APKTNSSTSPSLETREPPGAPAGGQL 2223
>gi|110735439 Werner syndrome protein [Homo sapiens]
Length = 1432
Score = 35.4 bits (80), Expect = 0.34
Identities = 31/104 (29%), Positives = 48/104 (46%), Gaps = 10/104 (9%)
Query: 614 SDRQLPQVLHMSELLNRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVN-MP 672
S + QV LN G +H+G+ ++ + F R ++ + AT F MG+N
Sbjct: 773 SRKMTQQVTGELRKLNLSCGTYHAGMSFSTRKDIHHRFVRDEIQCVIATIAFGMGINKAD 832
Query: 673 ARTVVFDSMRKHDGSTFRDLLPGEYVQMAGRAGRRGLDPTGTVI 716
R V+ H G+ +D+ Y Q GRAGR GL + V+
Sbjct: 833 IRQVI------HYGAP-KDM--ESYYQEIGRAGRDGLQSSCHVL 867
>gi|169218196 PREDICTED: similar to Werner syndrome ATP-dependent
helicase, partial [Homo sapiens]
Length = 1140
Score = 35.4 bits (80), Expect = 0.34
Identities = 31/104 (29%), Positives = 48/104 (46%), Gaps = 10/104 (9%)
Query: 614 SDRQLPQVLHMSELLNRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVN-MP 672
S + QV LN G +H+G+ ++ + F R ++ + AT F MG+N
Sbjct: 481 SRKMTQQVTGELRKLNLSCGTYHAGMSFSTRKDIHHRFVRDEIQCVIATIAFGMGINKAD 540
Query: 673 ARTVVFDSMRKHDGSTFRDLLPGEYVQMAGRAGRRGLDPTGTVI 716
R V+ H G+ +D+ Y Q GRAGR GL + V+
Sbjct: 541 IRQVI------HYGAP-KDM--ESYYQEIGRAGRDGLQSSCHVL 575
>gi|116812616 RecQ protein-like 4 [Homo sapiens]
Length = 1208
Score = 34.7 bits (78), Expect = 0.58
Identities = 26/76 (34%), Positives = 37/76 (48%), Gaps = 12/76 (15%)
Query: 635 HHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVNMPARTVVFDSMRKHDGSTFRDLLP 694
+H+G+ + V+ F +G ++V+ AT F MG++ P V H G L P
Sbjct: 744 YHAGMCSRERRRVQRAFMQGQLRVVVATVAFGMGLDRPDVRAVL-----HLG-----LPP 793
Query: 695 G--EYVQMAGRAGRRG 708
YVQ GRAGR G
Sbjct: 794 SFESYVQAVGRAGRDG 809
>gi|31543667 suppressor of var1, 3-like 1 [Homo sapiens]
Length = 786
Score = 34.7 bits (78), Expect = 0.58
Identities = 21/55 (38%), Positives = 33/55 (60%), Gaps = 5/55 (9%)
Query: 657 KVLFATETFAMGVNMPARTVVFDSMRKH--DGSTFRDLLP---GEYVQMAGRAGR 706
K+L AT+ MG+N+ R ++F S+ K + R+L P + +Q+AGRAGR
Sbjct: 419 KILVATDAIGMGLNLSIRRIIFYSLIKPSINEKGERELEPITTSQALQIAGRAGR 473
>gi|148596977 zinc finger protein 31 [Homo sapiens]
Length = 1043
Score = 34.7 bits (78), Expect = 0.58
Identities = 30/95 (31%), Positives = 40/95 (42%), Gaps = 16/95 (16%)
Query: 170 REEAEEEIDFEKDLLTIPPGFKKGMDFAPKDCPTPAPGLLSLSCMLEPLDLGGGDEDENE 229
R E E++I E+D+ PG A CPT A + +PLD G E+ENE
Sbjct: 629 RHEDEDQIS-EQDIFEGLPG-------ALSKCPTEA--------VCQPLDWGEDSENENE 672
Query: 230 AVGQPGGPRGDTVSASPCSAPLARASSLEDLVLKE 264
GQ G P + S L + + L L E
Sbjct: 673 DEGQWGNPSQEQWQESSSEEDLEKLIDHQGLYLAE 707
>gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo
sapiens]
Length = 875
Score = 33.9 bits (76), Expect = 1.00
Identities = 46/160 (28%), Positives = 66/160 (41%), Gaps = 18/160 (11%)
Query: 315 QKQAILHLERHDSVFVAAHTSAGKTVVAEYAI--ALAQKHMTRT-----IYTSPIKALSN 367
QKQ I + V AA T +GKT+ + AL + T T + SP + L+
Sbjct: 96 QKQTIGLALQGKDVLGAAKTGSGKTLAFLVPVLEALYRLQWTSTDGLGVLIISPTRELAY 155
Query: 368 QKFRDFR----NTFGDVGLLTGDVQLHPEA------SCLIMTT-EILRSMLYSGSDVIRD 416
Q F R N GL+ G L EA + L+ T +L+ M + S D
Sbjct: 156 QTFEVLRKVGKNHDFSAGLIIGGKDLKHEAERINNINILVCTPGRLLQHMDETVSFHATD 215
Query: 417 LEWVIFDEVHYINDVERGVVWEEVLIMLPDHVSIILLSAT 456
L+ ++ DE I D+ V+ LP +L SAT
Sbjct: 216 LQMLVLDEADRILDMGFADTMNAVIENLPKKRQTLLFSAT 255
>gi|13129006 nucleolar protein GU2 [Homo sapiens]
Length = 737
Score = 33.9 bits (76), Expect = 1.00
Identities = 23/73 (31%), Positives = 31/73 (42%), Gaps = 8/73 (10%)
Query: 636 HSGILPILKEIVEMLFSRGLVKVLFATETFAMGVNMPARTVVFDSMRKHDGSTFRDLLPG 695
H I +EI F G KVL AT A G+++P +V S D +
Sbjct: 419 HGDIAQSQREITLKGFREGSFKVLVATNVAARGLDIPEVDLVIQSSPPQDVES------- 471
Query: 696 EYVQMAGRAGRRG 708
Y+ +GR GR G
Sbjct: 472 -YIHRSGRTGRAG 483
>gi|45827755 transforming, acidic coiled-coil containing protein 2
isoform b [Homo sapiens]
Length = 1094
Score = 33.9 bits (76), Expect = 1.00
Identities = 37/136 (27%), Positives = 52/136 (38%), Gaps = 28/136 (20%)
Query: 141 ASQSLWGNPTQYPFWPGGMDEPTI--------------TDLNTREEAEEEIDFEKDLLTI 186
AS S + P P ++ PT+ TDL + ++ E FE T
Sbjct: 47 ASSSPVADDIIQPAAPADLESPTLAASSYHGDVVGQVSTDLIAQRSSDSEEAFETPESTT 106
Query: 187 PPGFKKGMDFAPKDCPTPAPGLL---SLSCMLEPLDLGGGDEDENEAVGQPGGPRGDTVS 243
P AP P P P ++ +S P + G G +E V P GPR D+V
Sbjct: 107 PVK-------APPAPPPPPPEVIPEPEVSTQPPPEEPGCG----SETVPVPDGPRSDSVE 155
Query: 244 ASPCSAPLARASSLED 259
SP P S++ D
Sbjct: 156 GSPFRPPSHSFSAVFD 171
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 50,665,012
Number of Sequences: 37866
Number of extensions: 2559215
Number of successful extensions: 7782
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 55
Number of HSP's that attempted gapping in prelim test: 7643
Number of HSP's gapped (non-prelim): 170
length of query: 1246
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1132
effective length of database: 13,930,794
effective search space: 15769658808
effective search space used: 15769658808
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.