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Search of human proteins with 67763814
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|67763814 death-inducing-protein [Homo sapiens]
(578 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|67763814 death-inducing-protein [Homo sapiens] 1156 0.0
gi|227496440 multiple C2 domains, transmembrane 2 isoform 1 [Hom... 67 3e-11
gi|50582996 multiple C2 domains, transmembrane 1 isoform S [Homo... 62 1e-09
gi|205361109 multiple C2 domains, transmembrane 1 isoform L [Hom... 62 1e-09
gi|60593095 GRAM domain containing 2 [Homo sapiens] 50 6e-06
gi|22035606 mitogen-activated protein kinase kinase kinase kinas... 50 7e-06
gi|22035602 mitogen-activated protein kinase kinase kinase kinas... 50 7e-06
gi|22035604 mitogen-activated protein kinase kinase kinase kinas... 50 7e-06
gi|148746195 trichohyalin [Homo sapiens] 44 3e-04
gi|213972568 dachshund 2 isoform c [Homo sapiens] 44 4e-04
gi|213972566 dachshund 2 isoform b [Homo sapiens] 44 4e-04
gi|16876441 dachshund 2 isoform a [Homo sapiens] 44 4e-04
gi|227496489 multiple C2 domains, transmembrane 2 isoform 2 [Hom... 43 7e-04
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 42 0.001
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 41 0.003
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 41 0.003
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 41 0.003
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 41 0.003
gi|112789536 troponin T3, skeletal, fast isoform 3 [Homo sapiens] 41 0.003
gi|112789541 troponin T3, skeletal, fast isoform 4 [Homo sapiens] 41 0.003
gi|68077168 DnaJ homology subfamily A member 5 isoform 1 [Homo s... 41 0.003
gi|68077166 DnaJ homology subfamily A member 5 isoform 2 [Homo s... 41 0.003
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 40 0.004
gi|4505101 microtubule-associated protein 7 [Homo sapiens] 40 0.004
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 40 0.004
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 40 0.004
gi|48255883 troponin T type 2, cardiac isoform 4 [Homo sapiens] 40 0.008
gi|239752551 PREDICTED: hypothetical protein [Homo sapiens] 40 0.008
gi|118918407 spectrin repeat containing, nuclear envelope 2 isof... 39 0.010
gi|118918403 spectrin repeat containing, nuclear envelope 2 isof... 39 0.010
>gi|67763814 death-inducing-protein [Homo sapiens]
Length = 578
Score = 1156 bits (2991), Expect = 0.0
Identities = 578/578 (100%), Positives = 578/578 (100%)
Query: 1 MLRRLDKIRFRGHKRDDFLDLAESPNASDTECSDEIPLKVPRTSPRDSEELRDPAGPGTL 60
MLRRLDKIRFRGHKRDDFLDLAESPNASDTECSDEIPLKVPRTSPRDSEELRDPAGPGTL
Sbjct: 1 MLRRLDKIRFRGHKRDDFLDLAESPNASDTECSDEIPLKVPRTSPRDSEELRDPAGPGTL 60
Query: 61 IMATGVQDFNRTEFDRLNEIKGHLEIALLEKHFLQEELRKLREETNAEMLRQELDRERQR 120
IMATGVQDFNRTEFDRLNEIKGHLEIALLEKHFLQEELRKLREETNAEMLRQELDRERQR
Sbjct: 61 IMATGVQDFNRTEFDRLNEIKGHLEIALLEKHFLQEELRKLREETNAEMLRQELDRERQR 120
Query: 121 RMELEQKVQEVLKARTEEQMAQQPPKGQAQASNGAERRSQGLSSRLQKWFYERFGEYVED 180
RMELEQKVQEVLKARTEEQMAQQPPKGQAQASNGAERRSQGLSSRLQKWFYERFGEYVED
Sbjct: 121 RMELEQKVQEVLKARTEEQMAQQPPKGQAQASNGAERRSQGLSSRLQKWFYERFGEYVED 180
Query: 181 FRFQPEENTVETEEPLSARRLTENMRRLKRGAKPVTNFVKNLSALSDWYSVYTSAIAFTV 240
FRFQPEENTVETEEPLSARRLTENMRRLKRGAKPVTNFVKNLSALSDWYSVYTSAIAFTV
Sbjct: 181 FRFQPEENTVETEEPLSARRLTENMRRLKRGAKPVTNFVKNLSALSDWYSVYTSAIAFTV 240
Query: 241 YMNAVWHGWAIPLFLFLAILRLSLNYLIARGWRIQWSIVPEVSEPVEPPKEDLTVSEKFQ 300
YMNAVWHGWAIPLFLFLAILRLSLNYLIARGWRIQWSIVPEVSEPVEPPKEDLTVSEKFQ
Sbjct: 241 YMNAVWHGWAIPLFLFLAILRLSLNYLIARGWRIQWSIVPEVSEPVEPPKEDLTVSEKFQ 300
Query: 301 LVLDVAQKAQNLFGKMADILEKIKNLFMWVQPEITQKLYVALWAAFLASCFFPYRLVGLA 360
LVLDVAQKAQNLFGKMADILEKIKNLFMWVQPEITQKLYVALWAAFLASCFFPYRLVGLA
Sbjct: 301 LVLDVAQKAQNLFGKMADILEKIKNLFMWVQPEITQKLYVALWAAFLASCFFPYRLVGLA 360
Query: 361 VGLYAGIKFFLIDFIFKRCPRLRAKYDTPYIIWRSLPTDPQLKERSSAAVSRRLQTTSSR 420
VGLYAGIKFFLIDFIFKRCPRLRAKYDTPYIIWRSLPTDPQLKERSSAAVSRRLQTTSSR
Sbjct: 361 VGLYAGIKFFLIDFIFKRCPRLRAKYDTPYIIWRSLPTDPQLKERSSAAVSRRLQTTSSR 420
Query: 421 SYVPSAPAGLGKEEDAGRFHSTKKGNFHEIFNLTENERPLAVCENGWRCCLINRDRKMPT 480
SYVPSAPAGLGKEEDAGRFHSTKKGNFHEIFNLTENERPLAVCENGWRCCLINRDRKMPT
Sbjct: 421 SYVPSAPAGLGKEEDAGRFHSTKKGNFHEIFNLTENERPLAVCENGWRCCLINRDRKMPT 480
Query: 481 DYIRNGVLYVTENYLCFESSKSGSSKRNKVIKLVDITDIQKYKVLSVLPGSGMGIAVSTP 540
DYIRNGVLYVTENYLCFESSKSGSSKRNKVIKLVDITDIQKYKVLSVLPGSGMGIAVSTP
Sbjct: 481 DYIRNGVLYVTENYLCFESSKSGSSKRNKVIKLVDITDIQKYKVLSVLPGSGMGIAVSTP 540
Query: 541 STQKPLVFGAMVHRDEAFETILSQYIKITSAAASGGDS 578
STQKPLVFGAMVHRDEAFETILSQYIKITSAAASGGDS
Sbjct: 541 STQKPLVFGAMVHRDEAFETILSQYIKITSAAASGGDS 578
>gi|227496440 multiple C2 domains, transmembrane 2 isoform 1 [Homo
sapiens]
Length = 878
Score = 67.4 bits (163), Expect = 3e-11
Identities = 50/184 (27%), Positives = 86/184 (46%), Gaps = 6/184 (3%)
Query: 186 EENTVETEEPLSARRLTENMRRLKRGAKPVTNFVKNLSALSDWYSVYTSAIAFTVYMNAV 245
E+ VE LS + L+ ++ R+KR + N ++ L + W S S IAF V++ V
Sbjct: 642 EKRFVEDSRKLSKKILSRDVDRVKRITMAIWNTMQFLKSCFQWESTLRSTIAFAVFLITV 701
Query: 246 WHG--WAIPLFLFLAILRLSLNYLIARGWRIQWSI----VPEVSEPVEPPKEDLTVSEKF 299
W+ + IPL L L + + + + IQ S + + + + E + E+
Sbjct: 702 WNFELYMIPLALLLIFVYNFIRPVKGKVSSIQDSQESTDIDDEEDEDDKESEKKGLIERI 761
Query: 300 QLVLDVAQKAQNLFGKMADILEKIKNLFMWVQPEITQKLYVALWAAFLASCFFPYRLVGL 359
+V D+ QN+ ++A E+IKN F W P ++ + L AA + F P R + L
Sbjct: 762 YMVQDIVSTVQNVLEEIASFGERIKNTFNWTVPFLSSLACLILAAATIILYFIPLRYIIL 821
Query: 360 AVGL 363
G+
Sbjct: 822 IWGI 825
>gi|50582996 multiple C2 domains, transmembrane 1 isoform S [Homo
sapiens]
Length = 778
Score = 62.0 bits (149), Expect = 1e-09
Identities = 64/244 (26%), Positives = 104/244 (42%), Gaps = 45/244 (18%)
Query: 186 EENTVETEEPLSARRLTENMRRLKRGAKPVTNFVKNLSALSDWYSVYTSAIAFTVYMNAV 245
E+ +E E LS + L N R+KR + N +++ DW S S AF +++ V
Sbjct: 538 EQKYIEEENRLSKQLLLRNFIRMKRCVMVLVNAAYYVNSCFDWDSPPRSLAAFVLFLFVV 597
Query: 246 WHG--WAIPLFLFLAILRLSLNYLI---ARGWRIQWSIVPEV--SEPVEPPKEDLTVSE- 297
W+ + IPL L +L L+ NY + + R + ++V ++ E E K+D +
Sbjct: 598 WNFELYMIPLVL---LLLLTWNYFLIISGKDNRQRDTVVEDMLEDEEEEDDKDDKDSEKK 654
Query: 298 ----KFQLVLDVAQKAQNLFGKMADILEKIKNLFMWVQPEITQKLYVALWAAFLASCFF- 352
K + +V QN+ ++A E+IKN F W P ++ W A +A C F
Sbjct: 655 GFINKIYAIQEVCVSVQNILDEVASFGERIKNTFNWTVPFLS-------WLAIVALCVFT 707
Query: 353 ------PYRLVGLAVGL----------YAGIKFFLIDFIFKRCPRLRAKYDTPYIIWRSL 396
P R + L G+ YA L+DF+ R D + ++ L
Sbjct: 708 AILYCIPLRYIVLVWGINKFTKKLRSPYAIDNNELLDFL------SRVPSDVQVVQYQEL 761
Query: 397 PTDP 400
DP
Sbjct: 762 KPDP 765
>gi|205361109 multiple C2 domains, transmembrane 1 isoform L [Homo
sapiens]
Length = 999
Score = 62.0 bits (149), Expect = 1e-09
Identities = 64/244 (26%), Positives = 104/244 (42%), Gaps = 45/244 (18%)
Query: 186 EENTVETEEPLSARRLTENMRRLKRGAKPVTNFVKNLSALSDWYSVYTSAIAFTVYMNAV 245
E+ +E E LS + L N R+KR + N +++ DW S S AF +++ V
Sbjct: 759 EQKYIEEENRLSKQLLLRNFIRMKRCVMVLVNAAYYVNSCFDWDSPPRSLAAFVLFLFVV 818
Query: 246 WHG--WAIPLFLFLAILRLSLNYLI---ARGWRIQWSIVPEV--SEPVEPPKEDLTVSE- 297
W+ + IPL L +L L+ NY + + R + ++V ++ E E K+D +
Sbjct: 819 WNFELYMIPLVL---LLLLTWNYFLIISGKDNRQRDTVVEDMLEDEEEEDDKDDKDSEKK 875
Query: 298 ----KFQLVLDVAQKAQNLFGKMADILEKIKNLFMWVQPEITQKLYVALWAAFLASCFF- 352
K + +V QN+ ++A E+IKN F W P ++ W A +A C F
Sbjct: 876 GFINKIYAIQEVCVSVQNILDEVASFGERIKNTFNWTVPFLS-------WLAIVALCVFT 928
Query: 353 ------PYRLVGLAVGL----------YAGIKFFLIDFIFKRCPRLRAKYDTPYIIWRSL 396
P R + L G+ YA L+DF+ R D + ++ L
Sbjct: 929 AILYCIPLRYIVLVWGINKFTKKLRSPYAIDNNELLDFL------SRVPSDVQVVQYQEL 982
Query: 397 PTDP 400
DP
Sbjct: 983 KPDP 986
>gi|60593095 GRAM domain containing 2 [Homo sapiens]
Length = 354
Score = 50.1 bits (118), Expect = 6e-06
Identities = 34/116 (29%), Positives = 65/116 (56%), Gaps = 17/116 (14%)
Query: 447 FHEIF-NLTENERPLAVCENGWRCCLINRDRKMPTDYIRNGVLYVTENYLCFESSKSGSS 505
+H++F ++ E L VC C + RD ++ G LY++ N+LCF +S G
Sbjct: 74 YHKLFKDVPLEEVVLKVCS-----CALQRD------FLLQGRLYISPNWLCFHASLFGKD 122
Query: 506 KRNKVIKLVDITDIQKYKVLSVLPGSGMGIAVSTPSTQKPLVFGAMVHRDEAFETI 561
+ VI +V + I+K+K+ +LP G+A++T ++QK +F +++ RD ++ +
Sbjct: 123 IK-VVIPVVSVQMIKKHKMARLLPN---GLAITTNTSQK-YIFVSLLSRDSVYDLL 173
>gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4
isoform 3 [Homo sapiens]
Length = 1212
Score = 49.7 bits (117), Expect = 7e-06
Identities = 50/166 (30%), Positives = 80/166 (48%), Gaps = 11/166 (6%)
Query: 44 SPRDSEELRDPAGPGTLIMATGVQDFNRTEFDRLNEIKGHLEIALLEKHFLQEELRKLRE 103
S + EE+ + G + I+ + R +F RL + AL + LQE+ +LRE
Sbjct: 326 SEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQ--QLRE 383
Query: 104 ETNAEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQPPKGQAQASNGAERRSQGLS 163
+ E +++L ERQ+R+E +QK Q + R EEQ ++ + + Q RR Q
Sbjct: 384 Q---EEYKRQLLAERQKRIE-QQKEQ---RRRLEEQQRRER-EARRQQEREQRRREQEEK 435
Query: 164 SRLQKWFYERFGEYVEDFRFQPEENTVETEEPLSARRLTENMRRLK 209
RL++ R E E R + E+ VE E+ R+L E R L+
Sbjct: 436 RRLEE-LERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLE 480
>gi|22035602 mitogen-activated protein kinase kinase kinase kinase 4
isoform 1 [Homo sapiens]
Length = 1166
Score = 49.7 bits (117), Expect = 7e-06
Identities = 50/166 (30%), Positives = 80/166 (48%), Gaps = 11/166 (6%)
Query: 44 SPRDSEELRDPAGPGTLIMATGVQDFNRTEFDRLNEIKGHLEIALLEKHFLQEELRKLRE 103
S + EE+ + G + I+ + R +F RL + AL + LQE+ +LRE
Sbjct: 326 SEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQ--QLRE 383
Query: 104 ETNAEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQPPKGQAQASNGAERRSQGLS 163
+ E +++L ERQ+R+E +QK Q + R EEQ ++ + + Q RR Q
Sbjct: 384 Q---EEYKRQLLAERQKRIE-QQKEQ---RRRLEEQQRRER-EARRQQEREQRRREQEEK 435
Query: 164 SRLQKWFYERFGEYVEDFRFQPEENTVETEEPLSARRLTENMRRLK 209
RL++ R E E R + E+ VE E+ R+L E R L+
Sbjct: 436 RRLEE-LERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLE 480
>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
isoform 2 [Homo sapiens]
Length = 1320
Score = 49.7 bits (117), Expect = 7e-06
Identities = 50/166 (30%), Positives = 80/166 (48%), Gaps = 11/166 (6%)
Query: 44 SPRDSEELRDPAGPGTLIMATGVQDFNRTEFDRLNEIKGHLEIALLEKHFLQEELRKLRE 103
S + EE+ + G + I+ + R +F RL + AL + LQE+ +LRE
Sbjct: 326 SEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQ--QLRE 383
Query: 104 ETNAEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQPPKGQAQASNGAERRSQGLS 163
+ E +++L ERQ+R+E +QK Q + R EEQ ++ + + Q RR Q
Sbjct: 384 Q---EEYKRQLLAERQKRIE-QQKEQ---RRRLEEQQRRER-EARRQQEREQRRREQEEK 435
Query: 164 SRLQKWFYERFGEYVEDFRFQPEENTVETEEPLSARRLTENMRRLK 209
RL++ R E E R + E+ VE E+ R+L E R L+
Sbjct: 436 RRLEE-LERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLE 480
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 44.3 bits (103), Expect = 3e-04
Identities = 44/169 (26%), Positives = 74/169 (43%), Gaps = 23/169 (13%)
Query: 59 TLIMATGVQDFNRTEFDRLNEIKGHLEIALLEKHFLQEELRKLREE-----TNAEMLRQE 113
TL +Q+ R E L E + L+ EK QE+ R+ REE ++LR+E
Sbjct: 888 TLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREE 947
Query: 114 LDRERQRRMELEQKVQEVLKARTEEQMAQQPPKGQAQASNGAERRSQGLSS--------- 164
++ R++ E + + + L+ + E+ + ++P K + Q R + L
Sbjct: 948 REKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREE 1007
Query: 165 ----RLQKWFYERFGEYVEDFRFQPEENTVETEEPLSARRLTENMRRLK 209
R Q+W ER +Y + Q EE + EE RRL E R+ +
Sbjct: 1008 REKRRRQEW--ER--QYRKKDELQQEEEQLLREE-REKRRLQERERQYR 1051
Score = 44.3 bits (103), Expect = 3e-04
Identities = 37/125 (29%), Positives = 58/125 (46%), Gaps = 14/125 (11%)
Query: 90 EKHFLQEELRKLREETNAEMLRQEL---DRERQRRMELEQ--KVQEVLKARTEEQMAQQP 144
EK LQE R+ REE + ++L +RE +RR ELE+ + +E L+ E+ + ++P
Sbjct: 1039 EKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEP 1098
Query: 145 PKGQAQASNGAERRSQGL---------SSRLQKWFYERFGEYVEDFRFQPEENTVETEEP 195
K + Q R + L R ++ E +Y E+ Q EE + EEP
Sbjct: 1099 EKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEP 1158
Query: 196 LSARR 200
RR
Sbjct: 1159 EKRRR 1163
Score = 42.0 bits (97), Expect = 0.002
Identities = 29/112 (25%), Positives = 55/112 (49%), Gaps = 1/112 (0%)
Query: 90 EKHFLQEELRKLREETNAEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQPPKGQA 149
E+ LQ+E +L E + RQE +R+ +++ EL+Q+ +++L+ E++ Q+ +
Sbjct: 992 EEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYR 1051
Query: 150 QASNGAERRSQGL-SSRLQKWFYERFGEYVEDFRFQPEENTVETEEPLSARR 200
+ + Q L R + E +Y ++ Q EE + EEP RR
Sbjct: 1052 EEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRR 1103
Score = 40.4 bits (93), Expect = 0.004
Identities = 24/98 (24%), Positives = 49/98 (50%)
Query: 90 EKHFLQEELRKLREETNAEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQPPKGQA 149
E+ LQ+E +L E + RQEL+R+ + E++Q+ +++L+ E++ Q+ +
Sbjct: 1112 EEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYR 1171
Query: 150 QASNGAERRSQGLSSRLQKWFYERFGEYVEDFRFQPEE 187
+ + Q L +K ER +Y E+ Q ++
Sbjct: 1172 EEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQK 1209
Score = 38.9 bits (89), Expect = 0.013
Identities = 31/119 (26%), Positives = 54/119 (45%), Gaps = 2/119 (1%)
Query: 90 EKHFLQEELRKLREETNAEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQPPKGQA 149
E+ QEE + LREE RQE +R+ + EL+Q+ +++L+ E++ Q+ +
Sbjct: 1083 EEELQQEEEQLLREEPEKRR-RQERERQCREEEELQQEEEQLLREEREKRRRQELERQYR 1141
Query: 150 QASNGAERRSQGLSSRLQKWFYERF-GEYVEDFRFQPEENTVETEEPLSARRLTENMRR 207
+ + Q L +K + +Y E+ Q EE + EE R+ E R
Sbjct: 1142 EEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYR 1200
Score = 38.1 bits (87), Expect = 0.022
Identities = 37/117 (31%), Positives = 56/117 (47%), Gaps = 17/117 (14%)
Query: 94 LQEELRKLREETNAEMLRQELDRERQRRMELEQKV---QEVLKARTEEQMAQQPPKGQAQ 150
LQEE +LR ++ RQEL RERQ + +Q++ Q++ + + EE+ QQ + + Q
Sbjct: 271 LQEEEEQLR-----KLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQ 325
Query: 151 ASNGAERRSQGLSSRLQKWFYERFGEYVEDFRFQPEENTVETEEPLSARRLTENMRR 207
ERR Q R Q+ E+ + R + EE E + RR E RR
Sbjct: 326 -----ERREQQEERREQQLRREQEERREQQLRREQEEERREQQ----LRREQEEERR 373
Score = 38.1 bits (87), Expect = 0.022
Identities = 33/119 (27%), Positives = 55/119 (46%), Gaps = 3/119 (2%)
Query: 95 QEELRK-LREETNAEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQPPKGQAQASN 153
QEE R L+ E E QE +++ +R + E++ + LK EE+ QQ + Q
Sbjct: 451 QEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRRE 510
Query: 154 GAERRSQGLSSRLQKWFYERFGEYVEDFRFQPEENTVETEEPLSARRLTENMR--RLKR 210
ERR Q L + ++ ++ + R + EE + + +RL + R RLKR
Sbjct: 511 QEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKR 569
Score = 38.1 bits (87), Expect = 0.022
Identities = 43/177 (24%), Positives = 77/177 (43%), Gaps = 29/177 (16%)
Query: 46 RDSEELRDPAGPGTLIMATGVQDFNRTEFDRLNEIKGHLEIALLEKHFLQEELRKLREET 105
R+ EE RD Q R E R +K E LE+ +EE+ +L +E
Sbjct: 569 REQEERRD-------------QLLKREEERRQQRLKREQE-ERLEQRLKREEVERLEQEE 614
Query: 106 NAE--MLRQELDRERQRRM----ELEQKVQEVLKARTEEQMAQQPPKGQAQ--------A 151
E + R+E + ER++++ E E++ Q+ L+ +E+ Q+ + + +
Sbjct: 615 RREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKR 674
Query: 152 SNGAERRSQGLSSRLQKWFYERFGEYVEDFRFQPEENTVETEEPLSAR-RLTENMRR 207
+ ERR Q L+ Q+ ER + +++Q E + + +R R E RR
Sbjct: 675 EHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRR 731
Score = 37.7 bits (86), Expect = 0.029
Identities = 35/150 (23%), Positives = 64/150 (42%), Gaps = 21/150 (14%)
Query: 71 RTEFDRLNEIKGHLEIALLEKHFLQEELRKLREETNAEMLRQE------------LDRER 118
R E +R + + E+ E+ L+EE K R + R+E +RE+
Sbjct: 1073 RQELER--QYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREK 1130
Query: 119 QRRMELEQKVQEVLKARTEEQ--MAQQPPKGQAQASNGAERRSQGLSSRLQKWFYERFGE 176
+RR ELE++ +E + + EE+ + ++P K + Q R + L ++ E
Sbjct: 1131 RRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREE--- 1187
Query: 177 YVEDFRFQPEENTVETEEPLSARRLTENMR 206
++ R Q E EE L ++ + R
Sbjct: 1188 --QEKRRQERERQYREEEELQRQKRKQRYR 1215
Score = 37.7 bits (86), Expect = 0.029
Identities = 36/127 (28%), Positives = 61/127 (48%), Gaps = 8/127 (6%)
Query: 90 EKHFLQEELRKLREETNAEMLRQELDRE---RQRRMELEQKVQEVLK-ARTEEQMAQQPP 145
EK QE R+ REE + ++L RE ++RR ELE++ +E + + EEQ+ ++
Sbjct: 1129 EKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQ 1188
Query: 146 KGQAQASNGAERRSQGLSSRLQKWFYERFGEYVEDFRFQPE---ENTVETEEPLSARRLT 202
+ + Q R + L + +K Y R + D ++Q E EN V + R
Sbjct: 1189 EKRRQERERQYREEEELQRQKRKQRY-RDEDQRSDLKWQWEPEKENAVRDNKVYCKGREN 1247
Query: 203 ENMRRLK 209
E R+L+
Sbjct: 1248 EQFRQLE 1254
Score = 37.7 bits (86), Expect = 0.029
Identities = 37/124 (29%), Positives = 58/124 (46%), Gaps = 18/124 (14%)
Query: 95 QEELRKLREETNAEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQPPKGQ--AQAS 152
QE RK REE E LRQE + ++ R E ++K +E EEQ+ Q+ + Q Q
Sbjct: 1767 QERDRKFREE---EQLRQEREEQQLRSQESDRKFRE------EEQLRQEREEQQLRPQQR 1817
Query: 153 NGA---ERRSQGLSSRLQKWFYERFGEYVEDFRFQPEENTVETEEPL----SARRLTENM 205
+G E L + Q+ ER +Y + +F +E + E+ L +R E
Sbjct: 1818 DGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERE 1877
Query: 206 RRLK 209
R+L+
Sbjct: 1878 RKLR 1881
Score = 36.6 bits (83), Expect = 0.065
Identities = 33/144 (22%), Positives = 60/144 (41%), Gaps = 18/144 (12%)
Query: 67 QDFNRTEFDRLNEIKGHLEIALLEKHFLQEELRKLREETNAEMLRQELDRERQRRMELEQ 126
Q R + +R ++ E LE+ ++ L++ +EE ++L++E +R +QR
Sbjct: 536 QQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQR------ 589
Query: 127 KVQEVLKARTEEQMAQQPPKGQAQASNGAERRSQGLSSRLQKWFYERFGEYVEDFRFQPE 186
LK EE++ Q+ + + + ERR Q L E E + E
Sbjct: 590 -----LKREQEERLEQRLKREEVERLEQEERREQRLKR-------EEPEEERRQQLLKSE 637
Query: 187 ENTVETEEPLSARRLTENMRRLKR 210
E ++ L + +RLKR
Sbjct: 638 EQEERRQQQLRREQQERREQRLKR 661
Score = 36.6 bits (83), Expect = 0.065
Identities = 35/132 (26%), Positives = 58/132 (43%), Gaps = 21/132 (15%)
Query: 90 EKHFLQE--ELRKLREETNAEMLRQELDRERQRR----------MELEQKVQEVLKARTE 137
E+ LQE E R+ +E+ + R +L+ ER+RR E +K Q++L+ E
Sbjct: 852 EEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEE 911
Query: 138 EQMAQQPPKGQAQASNGAERRSQGL---------SSRLQKWFYERFGEYVEDFRFQPEEN 188
E ++ K + Q R + L R ++ ER +Y +D + Q +E
Sbjct: 912 ELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEE 971
Query: 189 TVETEEPLSARR 200
+ EEP RR
Sbjct: 972 QLLGEEPEKRRR 983
Score = 36.2 bits (82), Expect = 0.085
Identities = 33/117 (28%), Positives = 62/117 (52%), Gaps = 9/117 (7%)
Query: 95 QEELRKLREETNAEMLRQELDRER-QRRMELEQKVQEVLKARTEEQMAQQPPKGQAQASN 153
+++LR+ +EE + L+++ + ER Q+R+ EQ+++ + R E+ + ++ K Q
Sbjct: 504 EQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQ--- 560
Query: 154 GAERRSQGLSSRLQKWFYERFGEYVEDFRFQPEENTVETEEPLSARRLTENMRRLKR 210
ERR Q L R Q+ ++ + E+ R Q + E EE L R E + RL++
Sbjct: 561 --ERREQRL-KREQEERRDQLLKREEERRQQRLKR--EQEERLEQRLKREEVERLEQ 612
Score = 35.8 bits (81), Expect = 0.11
Identities = 26/118 (22%), Positives = 57/118 (48%), Gaps = 5/118 (4%)
Query: 95 QEELRKLREETNAEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQPPKGQAQASNG 154
+++LR+ ++ + LR+E R++++ EQ+++ + R E+Q+ ++ + + + +
Sbjct: 380 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHE 439
Query: 155 AERRSQGLSSRLQK---WF--YERFGEYVEDFRFQPEENTVETEEPLSARRLTENMRR 207
ERR Q L ++ W E + ++ R Q + E E +L E RR
Sbjct: 440 QERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERR 497
Score = 35.4 bits (80), Expect = 0.14
Identities = 37/145 (25%), Positives = 67/145 (46%), Gaps = 15/145 (10%)
Query: 67 QDFNRTEFDR-LNEIKGHLEIALLEKHFLQEELRKLREETNAEMLRQELDRERQRRMELE 125
Q +R E DR E + L ++ F ++ELR E Q+L R++++R L+
Sbjct: 1476 QQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQ 1535
Query: 126 QKVQEVLKARTEEQMAQQPPKGQAQASNGAERRSQGLSSRLQKWFYERFGEYVEDFRFQP 185
++ Q + R +++ + K + + ER Q LS + ER D +F+
Sbjct: 1536 EEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQ------ER------DRKFRL 1583
Query: 186 EENTVETEEPLSARRLTENMRRLKR 210
EE V +E R+ E+ ++L+R
Sbjct: 1584 EEQKVRRQE--QERKFMEDEQQLRR 1606
Score = 34.7 bits (78), Expect = 0.25
Identities = 28/100 (28%), Positives = 51/100 (51%), Gaps = 10/100 (10%)
Query: 95 QEELRKLREETNAEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQPPKGQAQASNG 154
QE RK+ EE E LR E + ++ RR E ++K +E EEQ+ Q+ + Q + S
Sbjct: 1743 QERYRKILEE---EQLRPEREEQQLRRQERDRKFRE------EEQLRQEREEQQLR-SQE 1792
Query: 155 AERRSQGLSSRLQKWFYERFGEYVEDFRFQPEENTVETEE 194
++R+ + Q+ ++ D +++ EE ++ EE
Sbjct: 1793 SDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEE 1832
Score = 34.3 bits (77), Expect = 0.32
Identities = 27/116 (23%), Positives = 57/116 (49%), Gaps = 4/116 (3%)
Query: 95 QEELRKLREETNAEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQPPKGQAQASNG 154
+++LR+ ++ + LR+E + ER + +++ ++ LK R +E+ + + +
Sbjct: 410 EQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLK-REQEERRDWLKREEETERHE 468
Query: 155 AERRSQGLSSRLQKWFYERFGEYVEDFRFQPEENTVETEEPLSARRLTENMRRLKR 210
ERR Q L ++ ER+ + E+ R + +E E+ L + +RLKR
Sbjct: 469 QERRKQQLKRDQEEERRERWLKLEEEERREQQE---RREQQLRREQEERREQRLKR 521
Score = 33.9 bits (76), Expect = 0.42
Identities = 24/116 (20%), Positives = 53/116 (45%), Gaps = 7/116 (6%)
Query: 95 QEELRKLREETNAEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQPPKGQAQASNG 154
++ELR+ R+E + R +++ +R+ E E++ Q+ + +E+ QQ + + Q
Sbjct: 283 RQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRRE 342
Query: 155 AERRSQGLSSRLQKWFYERFGEYVEDFRFQPEENTVETEEPLSARRLTENMRRLKR 210
E R + R Q+ E + + + E+ E+ L + ++L+R
Sbjct: 343 QEERREQQLRREQE-------EERREQQLRREQEEERREQQLRREQQLRREQQLRR 391
Score = 33.9 bits (76), Expect = 0.42
Identities = 34/115 (29%), Positives = 55/115 (47%), Gaps = 12/115 (10%)
Query: 90 EKHFLQEELR---KLREETNAEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQPPK 146
E+ LQ+ LR +LR E E Q L RE ++R+E E++ Q LK EE+ Q +
Sbjct: 524 EEERLQQRLRSEQQLRRE-QEERREQLLKREEEKRLEQERREQR-LKREQEERRDQLLKR 581
Query: 147 GQAQASNGAER-RSQGLSSRLQKWFYERFGEYVEDFRFQPEENTVETEEPLSARR 200
+ + +R + + L RL++ ER + + E ++ EEP RR
Sbjct: 582 EEERRQQRLKREQEERLEQRLKREEVERLEQE------ERREQRLKREEPEEERR 630
Score = 33.9 bits (76), Expect = 0.42
Identities = 31/129 (24%), Positives = 59/129 (45%), Gaps = 12/129 (9%)
Query: 90 EKHFLQEELRKLREETNAEMLRQELDRERQRRMELEQKVQEVL--------KARTEEQMA 141
++ FLQEE ++LR + + RQ+ DR+ + +L Q+ +E K R EEQ
Sbjct: 1530 QRKFLQEE-QQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKV 1588
Query: 142 QQPPKGQAQASNGAERRSQGLSSRLQKWFYERFGEYVEDFRFQPEENTVETEEPLSARRL 201
++ + + + + R Q +L++ ER ++ ED + E + R+
Sbjct: 1589 RRQEQERKFMEDEQQLRRQEGQQQLRQ---ERDRKFREDEQLLQEREEQQLHRQERDRKF 1645
Query: 202 TENMRRLKR 210
E +L+R
Sbjct: 1646 LEEEPQLRR 1654
Score = 33.5 bits (75), Expect = 0.55
Identities = 31/129 (24%), Positives = 60/129 (46%), Gaps = 15/129 (11%)
Query: 91 KHFLQEELRKLREETNAEMLRQE-----LDRERQRRMELEQKVQEVLKARTEEQMAQQPP 145
+ FL+EE R R+E + L++E +RE+Q R + ++K +E E+Q+++Q
Sbjct: 1374 RKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFRE-----EEQQLSRQER 1428
Query: 146 ----KGQAQASNGAERRSQGLSSRLQKWFYERFGEYVEDFRFQPEENTVETEEPLSARRL 201
+ + Q ER + L Q+ ER ++ E+ + E + R+
Sbjct: 1429 DRKFREEEQQVRRQERERKFLEEE-QQLRQERHRKFREEEQLLQEREEQQLHRQERDRKF 1487
Query: 202 TENMRRLKR 210
E ++L+R
Sbjct: 1488 LEEEQQLRR 1496
Score = 33.1 bits (74), Expect = 0.72
Identities = 35/122 (28%), Positives = 56/122 (45%), Gaps = 17/122 (13%)
Query: 95 QEELR--KLREETNAEMLRQELDRERQ---RRMEL----EQKVQEVLKARTEEQMAQQPP 145
Q+E R +L+ E E L Q L RE + R EL +++ +E +K+R P
Sbjct: 651 QQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRI--------P 702
Query: 146 KGQAQASNGAERRSQGLSSRLQKWFYERFGEYVEDFRFQPEENTVETEEPLSARRLTENM 205
K Q Q + A+ R + SR +K +R + E+ R + E EE + R+ E
Sbjct: 703 KWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEE 762
Query: 206 RR 207
+R
Sbjct: 763 QR 764
Score = 33.1 bits (74), Expect = 0.72
Identities = 43/146 (29%), Positives = 65/146 (44%), Gaps = 28/146 (19%)
Query: 90 EKHFLQEELRKLREETNAEMLRQELDR------ERQRRMELEQKVQEV---------LKA 134
E+ Q+ RK REE ++ RQE DR ++ RR E E+K E K
Sbjct: 1405 EQQLRQDRDRKFREE-EQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKF 1463
Query: 135 RTEEQMAQQPPKGQAQASNGAERRSQGLSSRLQKWFYERFGEYVE-DFRFQ-PEENTVET 192
R EEQ+ Q+ + Q + ER + L Q ER ++ E + R Q PE +E
Sbjct: 1464 REEEQLLQE---REEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEE 1520
Query: 193 EEPLSARRL-------TENMRRLKRG 211
E+ L ++ + +RR +RG
Sbjct: 1521 EQQLHRQQRQRKFLQEEQQLRRQERG 1546
Score = 33.1 bits (74), Expect = 0.72
Identities = 34/126 (26%), Positives = 57/126 (45%), Gaps = 20/126 (15%)
Query: 95 QEELRKLREETNAEMLRQELDR------ERQRRMELEQKVQEVLKARTEEQMAQQPPKGQ 148
QE RK REE ++ RQE +R ++ RR ELE+K +E EEQ+ Q+ + Q
Sbjct: 1687 QERDRKFREEEQ-QLRRQERERKFLQEEQQLRRQELERKFRE------EEQLRQETEQEQ 1739
Query: 149 AQASNGAER-------RSQGLSSRLQKWFYERFGEYVEDFRFQPEENTVETEEPLSARRL 201
+ + R + +L++ +R E R + EE + ++E R
Sbjct: 1740 LRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFRE 1799
Query: 202 TENMRR 207
E +R+
Sbjct: 1800 EEQLRQ 1805
Score = 32.7 bits (73), Expect = 0.94
Identities = 37/116 (31%), Positives = 53/116 (45%), Gaps = 10/116 (8%)
Query: 94 LQEELRKLREETNAEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQPPKGQAQ--A 151
L++E KL+EE ++EL E ++ +LE+ QE+ + R EE+ QQ + + Q
Sbjct: 253 LRKEEEKLQEEEPQR--QRELQEEEEQLRKLER--QELRRERQEEEQQQQRLRREQQLRR 308
Query: 152 SNGAERRSQGLSSRLQKWFYERFGEYVEDFRFQPEENTVETEEPLSARRLTENMRR 207
ERR Q R Q+ ER E E+ R Q E RR E RR
Sbjct: 309 KQEEERREQQEERREQQ---ER-REQQEERREQQLRREQEERREQQLRREQEEERR 360
Score = 32.7 bits (73), Expect = 0.94
Identities = 30/122 (24%), Positives = 53/122 (43%), Gaps = 8/122 (6%)
Query: 95 QEELRKLREETNAEMLRQELDRERQRRMEL--EQKVQEVLKARTEEQMAQQPPKGQAQAS 152
QEE + LREE + RQE DR+ + +L E++ Q + + + + ++ + Q Q
Sbjct: 1315 QEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGR 1374
Query: 153 NGAERRSQGLSSRLQKWFYER-FGEYVEDFRFQPEENTVETEEPLSARRLTENMRRLKRG 211
E RL++ ER F + + R Q E + + R + + R +R
Sbjct: 1375 KFLEE-----EQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERD 1429
Query: 212 AK 213
K
Sbjct: 1430 RK 1431
Score = 32.3 bits (72), Expect = 1.2
Identities = 25/121 (20%), Positives = 57/121 (47%), Gaps = 4/121 (3%)
Query: 90 EKHFLQEELRKLREETNAEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQPPKGQA 149
E+ +++LR+ ++ + LR+E R++++ EQ+++ + R E+Q+ ++ Q
Sbjct: 369 EEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQ---QL 425
Query: 150 QASNGAERRSQGLSSRLQKWFYERFGEYVEDFRFQPEENTVETEEPLSARRLTENMRRLK 209
+ ER Q ++ +R E D+ + EE T E+ ++L + +
Sbjct: 426 RREQEEERHEQKHEQERREQRLKREQEERRDW-LKREEETERHEQERRKQQLKRDQEEER 484
Query: 210 R 210
R
Sbjct: 485 R 485
Score = 32.0 bits (71), Expect = 1.6
Identities = 32/151 (21%), Positives = 63/151 (41%), Gaps = 10/151 (6%)
Query: 67 QDFNRTEFDRLNEIKGHLEIALLEKHFLQEELRKLREETNAEMLRQELDRERQRRMELEQ 126
Q R + +R + +K E E+H + ++L+ + E + L E + R E ++
Sbjct: 445 QRLKREQEERRDWLKREEET---ERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQE 501
Query: 127 KVQEVLKARTEEQMAQQPPKGQAQASNGAERRSQGLSSRLQKWFYERFGEYVEDFRFQPE 186
+ ++ L+ EE+ Q+ + + + RS+ R Q+ E+ + E+ R + E
Sbjct: 502 RREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQE 561
Query: 187 -------ENTVETEEPLSARRLTENMRRLKR 210
E + L R +RLKR
Sbjct: 562 RREQRLKREQEERRDQLLKREEERRQQRLKR 592
Score = 31.6 bits (70), Expect = 2.1
Identities = 31/124 (25%), Positives = 55/124 (44%), Gaps = 9/124 (7%)
Query: 90 EKHFLQEELRKLREETNAEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQPPKGQA 149
E+ F+++E ++LR + + LRQE DR+ + E EQ +QE EEQ + + +
Sbjct: 1594 ERKFMEDE-QQLRRQEGQQQLRQERDRKFR---EDEQLLQE-----REEQQLHRQERDRK 1644
Query: 150 QASNGAERRSQGLSSRLQKWFYERFGEYVEDFRFQPEENTVETEEPLSARRLTENMRRLK 209
+ R Q +L+ +F E + + E+ E R + +RR +
Sbjct: 1645 FLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQE 1704
Query: 210 RGAK 213
R K
Sbjct: 1705 RERK 1708
Score = 31.6 bits (70), Expect = 2.1
Identities = 24/110 (21%), Positives = 53/110 (48%), Gaps = 5/110 (4%)
Query: 95 QEELRKLREETNAEMLRQELDRE-RQRRMELEQKVQEVLKARTEEQMAQQPPKGQAQASN 153
+EE + L+E ++ RQE DR+ R+ +L ++ +E + E+Q+ +Q + + +
Sbjct: 1670 REEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEE 1729
Query: 154 GAERRSQGLSSRLQKWFYERFGEYVEDFRFQPEENTVETEEPLSARRLTE 203
+ ++ R Q ER+ + +E+ + +PE + R+ E
Sbjct: 1730 QLRQETEQEQLRRQ----ERYRKILEEEQLRPEREEQQLRRQERDRKFRE 1775
Score = 31.2 bits (69), Expect = 2.7
Identities = 34/130 (26%), Positives = 54/130 (41%), Gaps = 14/130 (10%)
Query: 90 EKHFLQEELRKLREETNAEMLRQELDRERQRRMELEQ----KVQEVLKARTEEQMAQQPP 145
EK E+ + R + RQE +RR E EQ K E + EEQ+ ++
Sbjct: 156 EKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRR-- 213
Query: 146 KGQAQASNGAERRSQGLSSRLQKWFYERFGEYVEDFR-----FQPEENTVETEEPLSARR 200
+ G E + Q R + F E E +++R + EE ++ EEP R
Sbjct: 214 ELLELRRKGREEKQQQRRERQDRVFQE---EEEKEWRKRETVLRKEEEKLQEEEPQRQRE 270
Query: 201 LTENMRRLKR 210
L E +L++
Sbjct: 271 LQEEEEQLRK 280
Score = 31.2 bits (69), Expect = 2.7
Identities = 24/82 (29%), Positives = 39/82 (47%), Gaps = 3/82 (3%)
Query: 95 QEELRK---LREETNAEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQPPKGQAQA 151
QEE R+ LR E E Q+L RE+Q R E + + ++ L+ + + QQ + Q
Sbjct: 355 QEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 414
Query: 152 SNGAERRSQGLSSRLQKWFYER 173
RR Q L ++ +E+
Sbjct: 415 REQQLRREQQLRREQEEERHEQ 436
Score = 31.2 bits (69), Expect = 2.7
Identities = 33/114 (28%), Positives = 49/114 (42%), Gaps = 18/114 (15%)
Query: 95 QEELRKLREETNAEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQPPKGQAQASNG 154
Q E R L EE E R++ RER++ ++ ++ +E L+ R Q Q+ G +
Sbjct: 805 QREQRFLPEEEEKEQRRRQR-REREKELQFLEE-EEQLQRRERAQQLQEEEDGLQEDQ-- 860
Query: 155 AERRSQGLSSRLQKWFYERFGEYVEDFRFQPEENTVETEEPLSAR-RLTENMRR 207
ERR R QKW R+Q EE L A+ L E +R+
Sbjct: 861 -ERRRSQEQRRDQKW------------RWQLEEERKRRRHTLYAKPALQEQLRK 901
Score = 31.2 bits (69), Expect = 2.7
Identities = 41/165 (24%), Positives = 67/165 (40%), Gaps = 23/165 (13%)
Query: 67 QDFNRTEFDR-LNEIKGHLEIALLEKHFLQEEL-------RKLREETNA-------EMLR 111
Q +R E DR E + + E+ FL+EE RK REE ++ R
Sbjct: 1421 QQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHR 1480
Query: 112 QELDRERQRRMELEQKVQEVLKARTEEQMAQQPPK---GQAQASNGAERRSQGLSSRLQK 168
QE DR+ + ++ + K R +E +Q+P + + Q + +R+ + L Q
Sbjct: 1481 QERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQL 1540
Query: 169 WFYERFGEYVEDFRFQPEENTVETEEPLSARRLTENMRRLKRGAK 213
ER + R Q + EE L R + + R +R K
Sbjct: 1541 RRQERGQQ-----RRQDRDRKFREEEQLRQEREEQQLSRQERDRK 1580
Score = 30.8 bits (68), Expect = 3.6
Identities = 32/117 (27%), Positives = 51/117 (43%), Gaps = 14/117 (11%)
Query: 95 QEELRKLREETNAEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQPPKGQAQASNG 154
QEE ++ E + ++ + R RQ+R E E+++ A EEQ +Q +
Sbjct: 115 QEEDQRRFEPRDRQLEEEPGQRRRQKRQEQEREL-----AEGEEQSEKQ----ERLEQRD 165
Query: 155 AERRSQGLSSRLQKWFYERFGEYVEDFRFQP----EENTVETEEPLSARRLTENMRR 207
+RR + L + Q+W ER E+ + Q E EE L R L E R+
Sbjct: 166 RQRRDEELWRQRQEW-QEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRK 221
Score = 30.4 bits (67), Expect = 4.6
Identities = 26/124 (20%), Positives = 56/124 (45%), Gaps = 6/124 (4%)
Query: 90 EKHFLQEELRKLREETNAEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQPP---K 146
E+ +++ ++LR E ++E RE+Q +Q+ +E + R E+Q+ ++ +
Sbjct: 289 ERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERRE 348
Query: 147 GQAQASNGAERRSQGLSSRLQKWFYERFGEYVEDFRFQPEENTVETEEPLSARRLTENMR 206
Q + ERR Q L ++ ER + + + E + E+ L + +
Sbjct: 349 QQLRREQEEERREQQLRREQEE---ERREQQLRREQQLRREQQLRREQQLRREQQLRREQ 405
Query: 207 RLKR 210
+L+R
Sbjct: 406 QLRR 409
Score = 29.6 bits (65), Expect = 7.9
Identities = 33/123 (26%), Positives = 54/123 (43%), Gaps = 12/123 (9%)
Query: 95 QEELRK--LREETNAEMLRQELDRE-----RQRRMELEQKVQEVLKARTEEQMAQQPPKG 147
QEE R+ LR E E Q+L RE R++++ EQ+++ + R E+Q+ ++
Sbjct: 343 QEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLR 402
Query: 148 QAQASNGAERRSQGLSSRLQKWFYERFGEYVEDFRFQPEENTVETEEPLSARRLTENMRR 207
+ Q RR Q L Q ++ E+ R + + E+ L R E
Sbjct: 403 REQQL----RREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLK-REQEERRDW 457
Query: 208 LKR 210
LKR
Sbjct: 458 LKR 460
>gi|213972568 dachshund 2 isoform c [Homo sapiens]
Length = 432
Score = 43.9 bits (102), Expect = 4e-04
Identities = 39/127 (30%), Positives = 66/127 (51%), Gaps = 17/127 (13%)
Query: 21 LAESPNASD--TECSDEIPLKVP-RTSPRDSEELRD----PAG-PGTLIMATGVQDFNRT 72
++ SP+ D E +E+P+++P SP D +L PAG PG I A +
Sbjct: 232 VSSSPSQMDHHLERMEEVPVQIPIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETL 291
Query: 73 EFDRLNEIKGHLEIALLEKHFLQEELRKLREETNAEMLRQELDRERQRRMELEQKVQEVL 132
L I+G L++AL ++++++ ++E LR EL RER+ R LE+++ L
Sbjct: 292 ----LTNIQGLLKVALDNARIQEKQIQQEKKE-----LRLELYREREIRENLERQLAVEL 342
Query: 133 KARTEEQ 139
++RT Q
Sbjct: 343 QSRTTMQ 349
>gi|213972566 dachshund 2 isoform b [Homo sapiens]
Length = 571
Score = 43.9 bits (102), Expect = 4e-04
Identities = 39/127 (30%), Positives = 66/127 (51%), Gaps = 17/127 (13%)
Query: 21 LAESPNASD--TECSDEIPLKVP-RTSPRDSEELRD----PAG-PGTLIMATGVQDFNRT 72
++ SP+ D E +E+P+++P SP D +L PAG PG I A +
Sbjct: 386 VSSSPSQMDHHLERMEEVPVQIPIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETL 445
Query: 73 EFDRLNEIKGHLEIALLEKHFLQEELRKLREETNAEMLRQELDRERQRRMELEQKVQEVL 132
L I+G L++AL ++++++ ++E LR EL RER+ R LE+++ L
Sbjct: 446 ----LTNIQGLLKVALDNARIQEKQIQQEKKE-----LRLELYREREIRENLERQLAVEL 496
Query: 133 KARTEEQ 139
++RT Q
Sbjct: 497 QSRTTMQ 503
>gi|16876441 dachshund 2 isoform a [Homo sapiens]
Length = 599
Score = 43.9 bits (102), Expect = 4e-04
Identities = 39/127 (30%), Positives = 66/127 (51%), Gaps = 17/127 (13%)
Query: 21 LAESPNASD--TECSDEIPLKVP-RTSPRDSEELRD----PAG-PGTLIMATGVQDFNRT 72
++ SP+ D E +E+P+++P SP D +L PAG PG I A +
Sbjct: 399 VSSSPSQMDHHLERMEEVPVQIPIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETL 458
Query: 73 EFDRLNEIKGHLEIALLEKHFLQEELRKLREETNAEMLRQELDRERQRRMELEQKVQEVL 132
L I+G L++AL ++++++ ++E LR EL RER+ R LE+++ L
Sbjct: 459 ----LTNIQGLLKVALDNARIQEKQIQQEKKE-----LRLELYREREIRENLERQLAVEL 509
Query: 133 KARTEEQ 139
++RT Q
Sbjct: 510 QSRTTMQ 516
>gi|227496489 multiple C2 domains, transmembrane 2 isoform 2 [Homo
sapiens]
Length = 823
Score = 43.1 bits (100), Expect = 7e-04
Identities = 41/178 (23%), Positives = 65/178 (36%), Gaps = 49/178 (27%)
Query: 186 EENTVETEEPLSARRLTENMRRLKRGAKPVTNFVKNLSALSDWYSVYTSAIAFTVYMNAV 245
E+ VE LS + L+ ++ R+KR + N ++ L + W S S IAF
Sbjct: 642 EKRFVEDSRKLSKKILSRDVDRVKRITMAIWNTMQFLKSCFQWESTLRSTIAFA------ 695
Query: 246 WHGWAIPLFLFLAILRLSLNYLIARGWRIQWSIVPEVSEPVEPPKEDLTVSEKFQLVLDV 305
E K+ L E+ +V D+
Sbjct: 696 -----------------------------------------ESEKKGLI--ERIYMVQDI 712
Query: 306 AQKAQNLFGKMADILEKIKNLFMWVQPEITQKLYVALWAAFLASCFFPYRLVGLAVGL 363
QN+ ++A E+IKN F W P ++ + L AA + F P R + L G+
Sbjct: 713 VSTVQNVLEEIASFGERIKNTFNWTVPFLSSLACLILAAATIILYFIPLRYIILIWGI 770
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 42.4 bits (98), Expect = 0.001
Identities = 54/198 (27%), Positives = 80/198 (40%), Gaps = 31/198 (15%)
Query: 22 AESPNASDTECSDEIPLKVPRTSPRDSEELRDPAGPGTLIMAT----GVQDFNRTEFDRL 77
A SP S T + + P +P D+ L P P + + G D R E RL
Sbjct: 546 APSPAPSPTPAPPQKE-QPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTD--REEATRL 602
Query: 78 NEIKGHLEIALLEKHFLQEELRKLREETNAEMLRQELDRERQRRMELEQKVQEVLKARTE 137
L E+ R+ RE+ E + L ER +RM EQ +E
Sbjct: 603 ----------------LAEKRRQAREQREREEQERRLQAERDKRMREEQLAREAEARAER 646
Query: 138 EQMAQQPPKGQAQASNGAERRSQGLSSRLQKWFYE---RFGEYVEDFRFQPEENTVETEE 194
E A++ + +A+ AE+ Q RLQK E R E E R + E++ + E+
Sbjct: 647 EAEARRREEQEAREKAQAEQEEQ---ERLQKQKEEAEARSREEAERQRLEREKHFQQQEQ 703
Query: 195 PLSAR--RLTENMRRLKR 210
R RL E M+R ++
Sbjct: 704 ERQERRKRLEEIMKRTRK 721
Score = 32.7 bits (73), Expect = 0.94
Identities = 25/95 (26%), Positives = 45/95 (47%), Gaps = 15/95 (15%)
Query: 90 EKHFLQEELRK-------------LREETNAEMLRQELDRERQRRMELEQKVQEVLKART 136
E+H L +E R+ L +E A+ LR++ +ER+RR+E ++ E +A
Sbjct: 137 ERHKLAKERREERAKYLAAKKAVWLEKEEKAKALREKQLQERRRRLEEQRLKAEQRRAAL 196
Query: 137 EEQMAQQPPKGQAQASNGAER--RSQGLSSRLQKW 169
EE+ Q+ K + + +R + R Q+W
Sbjct: 197 EERQRQKLEKNKERYEAAIQRSVKKTWAEIRQQRW 231
Score = 30.4 bits (67), Expect = 4.6
Identities = 28/89 (31%), Positives = 41/89 (46%), Gaps = 22/89 (24%)
Query: 95 QEELRKLREETNA----EMLRQELDRER----------QRRMELEQKVQEVLKARTEEQM 140
QE L+K +EE A E RQ L+RE+ +RR LE+ ++ K+ E
Sbjct: 669 QERLQKQKEEAEARSREEAERQRLEREKHFQQQEQERQERRKRLEEIMKRTRKSEVSETK 728
Query: 141 AQQPPKGQAQASNGA-------ERRSQGL 162
+Q K +A A+ + E RS GL
Sbjct: 729 QKQDSK-EANANGSSPEPVKAVEARSPGL 756
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 41.2 bits (95), Expect = 0.003
Identities = 40/137 (29%), Positives = 67/137 (48%), Gaps = 21/137 (15%)
Query: 90 EKHFLQEELRKLREETNAEMLRQELDRERQRRMELE---QKVQEVLKARTEEQMA--QQP 144
E+ QEELR+ +EE +LR++ + ER+RR E E +K +E L+ + E+++A +Q
Sbjct: 747 EERKRQEELRRQQEE----ILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQR 802
Query: 145 PKGQAQASNGA------------ERRSQGLSSRLQKWFYERFGEYVEDFRFQPEENTVET 192
+ + Q A ERR Q R Q+ ++ E+ + + EEN +
Sbjct: 803 EEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRM 862
Query: 193 EEPLSARRLTENMRRLK 209
EE + R E R+ K
Sbjct: 863 EEEAARLRHEEEERKRK 879
Score = 35.0 bits (79), Expect = 0.19
Identities = 32/127 (25%), Positives = 53/127 (41%), Gaps = 15/127 (11%)
Query: 102 REETNAEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQPPKGQAQASNGAERRSQG 161
+E AEM + + ER+R+ EL ++ +E+L+ + EE+ + R +
Sbjct: 733 QERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKR--------------REEEE 778
Query: 162 LSSRLQKWFYERFGEYVEDFRFQPEENTVETEEPLSARRLTENMRRLKRGAKPVTNFVKN 221
L+ R Q+ R E R Q EE + +E + RRL E R + K K
Sbjct: 779 LARRKQEEALRRQREQEIALRRQREEEERQQQEE-ALRRLEERRREEEERRKQEELLRKQ 837
Query: 222 LSALSDW 228
+ W
Sbjct: 838 EEEAAKW 844
Score = 33.9 bits (76), Expect = 0.42
Identities = 33/104 (31%), Positives = 50/104 (48%), Gaps = 11/104 (10%)
Query: 94 LQEELRKLREETNAEMLRQELDRERQRR-MELEQKVQEVLKARTEEQMAQQPPKGQ---- 148
++EE +LR E E R+EL+ +RQ+ M Q+ QE L+ ++Q QQ + +
Sbjct: 862 MEEEAARLRHEEE-ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSS 920
Query: 149 ---AQASNGAERRSQGLSS--RLQKWFYERFGEYVEDFRFQPEE 187
Q SN +SQ S +QK ER + E+ R Q E
Sbjct: 921 STWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRE 964
Score = 33.1 bits (74), Expect = 0.72
Identities = 36/124 (29%), Positives = 58/124 (46%), Gaps = 17/124 (13%)
Query: 85 EIALLEKHFLQEELRKLREETNAEMLRQELDR-ERQRRMELEQKVQEVLKARTEEQMAQQ 143
E AL + + LR+ REE + + L R E +RR E E++ QE L + EE+ A+
Sbjct: 785 EEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAK- 843
Query: 144 PPKGQAQASNGAERRSQGLSSRLQKWFYERFGEYVEDFRFQPEENTVETEEPLSARRLTE 203
A+ A+RR + R+++ E R + EE + +E L +R E
Sbjct: 844 ----WAREEEEAQRRLEENRLRMEE----------EAARLRHEEEERKRKE-LEVQRQKE 888
Query: 204 NMRR 207
MR+
Sbjct: 889 LMRQ 892
Score = 32.3 bits (72), Expect = 1.2
Identities = 38/121 (31%), Positives = 58/121 (47%), Gaps = 14/121 (11%)
Query: 87 ALLEKHFLQEELRKLREETNAEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQPPK 146
A LE+ + E+R REE E RQE + RQ+ L ++ +E K R EE++A+
Sbjct: 729 AKLEQERREAEMRAKREEE--ERKRQE-ELRRQQEEILRRQQEEERKRREEEELAR---- 781
Query: 147 GQAQASNGAERRSQGLSSRLQKWFYERFGEYVEDFRFQPEENTVETEEPLSARRLTENMR 206
+ Q +R Q ++ R Q+ ER + E+ + EE E EE RR E +
Sbjct: 782 -RKQEEALRRQREQEIALRRQREEEER--QQQEEALRRLEERRREEEE----RRKQEELL 834
Query: 207 R 207
R
Sbjct: 835 R 835
Score = 31.2 bits (69), Expect = 2.7
Identities = 15/37 (40%), Positives = 25/37 (67%)
Query: 107 AEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQ 143
AE+ + E +RERQ R E ++ +E++KA ++Q QQ
Sbjct: 941 AEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQ 977
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 41.2 bits (95), Expect = 0.003
Identities = 40/137 (29%), Positives = 67/137 (48%), Gaps = 21/137 (15%)
Query: 90 EKHFLQEELRKLREETNAEMLRQELDRERQRRMELE---QKVQEVLKARTEEQMA--QQP 144
E+ QEELR+ +EE +LR++ + ER+RR E E +K +E L+ + E+++A +Q
Sbjct: 774 EERKRQEELRRQQEE----ILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQR 829
Query: 145 PKGQAQASNGA------------ERRSQGLSSRLQKWFYERFGEYVEDFRFQPEENTVET 192
+ + Q A ERR Q R Q+ ++ E+ + + EEN +
Sbjct: 830 EEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRM 889
Query: 193 EEPLSARRLTENMRRLK 209
EE + R E R+ K
Sbjct: 890 EEEAARLRHEEEERKRK 906
Score = 35.0 bits (79), Expect = 0.19
Identities = 32/127 (25%), Positives = 53/127 (41%), Gaps = 15/127 (11%)
Query: 102 REETNAEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQPPKGQAQASNGAERRSQG 161
+E AEM + + ER+R+ EL ++ +E+L+ + EE+ + R +
Sbjct: 760 QERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKR--------------REEEE 805
Query: 162 LSSRLQKWFYERFGEYVEDFRFQPEENTVETEEPLSARRLTENMRRLKRGAKPVTNFVKN 221
L+ R Q+ R E R Q EE + +E + RRL E R + K K
Sbjct: 806 LARRKQEEALRRQREQEIALRRQREEEERQQQEE-ALRRLEERRREEEERRKQEELLRKQ 864
Query: 222 LSALSDW 228
+ W
Sbjct: 865 EEEAAKW 871
Score = 33.9 bits (76), Expect = 0.42
Identities = 33/104 (31%), Positives = 50/104 (48%), Gaps = 11/104 (10%)
Query: 94 LQEELRKLREETNAEMLRQELDRERQRR-MELEQKVQEVLKARTEEQMAQQPPKGQ---- 148
++EE +LR E E R+EL+ +RQ+ M Q+ QE L+ ++Q QQ + +
Sbjct: 889 MEEEAARLRHEEE-ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSS 947
Query: 149 ---AQASNGAERRSQGLSS--RLQKWFYERFGEYVEDFRFQPEE 187
Q SN +SQ S +QK ER + E+ R Q E
Sbjct: 948 STWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRE 991
Score = 33.1 bits (74), Expect = 0.72
Identities = 36/124 (29%), Positives = 58/124 (46%), Gaps = 17/124 (13%)
Query: 85 EIALLEKHFLQEELRKLREETNAEMLRQELDR-ERQRRMELEQKVQEVLKARTEEQMAQQ 143
E AL + + LR+ REE + + L R E +RR E E++ QE L + EE+ A+
Sbjct: 812 EEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAK- 870
Query: 144 PPKGQAQASNGAERRSQGLSSRLQKWFYERFGEYVEDFRFQPEENTVETEEPLSARRLTE 203
A+ A+RR + R+++ E R + EE + +E L +R E
Sbjct: 871 ----WAREEEEAQRRLEENRLRMEE----------EAARLRHEEEERKRKE-LEVQRQKE 915
Query: 204 NMRR 207
MR+
Sbjct: 916 LMRQ 919
Score = 32.3 bits (72), Expect = 1.2
Identities = 38/121 (31%), Positives = 58/121 (47%), Gaps = 14/121 (11%)
Query: 87 ALLEKHFLQEELRKLREETNAEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQPPK 146
A LE+ + E+R REE E RQE + RQ+ L ++ +E K R EE++A+
Sbjct: 756 AKLEQERREAEMRAKREEE--ERKRQE-ELRRQQEEILRRQQEEERKRREEEELAR---- 808
Query: 147 GQAQASNGAERRSQGLSSRLQKWFYERFGEYVEDFRFQPEENTVETEEPLSARRLTENMR 206
+ Q +R Q ++ R Q+ ER + E+ + EE E EE RR E +
Sbjct: 809 -RKQEEALRRQREQEIALRRQREEEER--QQQEEALRRLEERRREEEE----RRKQEELL 861
Query: 207 R 207
R
Sbjct: 862 R 862
Score = 31.2 bits (69), Expect = 2.7
Identities = 15/37 (40%), Positives = 25/37 (67%)
Query: 107 AEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQ 143
AE+ + E +RERQ R E ++ +E++KA ++Q QQ
Sbjct: 968 AEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQ 1004
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 41.2 bits (95), Expect = 0.003
Identities = 40/137 (29%), Positives = 67/137 (48%), Gaps = 21/137 (15%)
Query: 90 EKHFLQEELRKLREETNAEMLRQELDRERQRRMELE---QKVQEVLKARTEEQMA--QQP 144
E+ QEELR+ +EE +LR++ + ER+RR E E +K +E L+ + E+++A +Q
Sbjct: 753 EERKRQEELRRQQEE----ILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQR 808
Query: 145 PKGQAQASNGA------------ERRSQGLSSRLQKWFYERFGEYVEDFRFQPEENTVET 192
+ + Q A ERR Q R Q+ ++ E+ + + EEN +
Sbjct: 809 EEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRM 868
Query: 193 EEPLSARRLTENMRRLK 209
EE + R E R+ K
Sbjct: 869 EEEAARLRHEEEERKRK 885
Score = 35.0 bits (79), Expect = 0.19
Identities = 32/127 (25%), Positives = 53/127 (41%), Gaps = 15/127 (11%)
Query: 102 REETNAEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQPPKGQAQASNGAERRSQG 161
+E AEM + + ER+R+ EL ++ +E+L+ + EE+ + R +
Sbjct: 739 QERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKR--------------REEEE 784
Query: 162 LSSRLQKWFYERFGEYVEDFRFQPEENTVETEEPLSARRLTENMRRLKRGAKPVTNFVKN 221
L+ R Q+ R E R Q EE + +E + RRL E R + K K
Sbjct: 785 LARRKQEEALRRQREQEIALRRQREEEERQQQEE-ALRRLEERRREEEERRKQEELLRKQ 843
Query: 222 LSALSDW 228
+ W
Sbjct: 844 EEEAAKW 850
Score = 33.9 bits (76), Expect = 0.42
Identities = 33/104 (31%), Positives = 50/104 (48%), Gaps = 11/104 (10%)
Query: 94 LQEELRKLREETNAEMLRQELDRERQRR-MELEQKVQEVLKARTEEQMAQQPPKGQ---- 148
++EE +LR E E R+EL+ +RQ+ M Q+ QE L+ ++Q QQ + +
Sbjct: 868 MEEEAARLRHEEE-ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSS 926
Query: 149 ---AQASNGAERRSQGLSS--RLQKWFYERFGEYVEDFRFQPEE 187
Q SN +SQ S +QK ER + E+ R Q E
Sbjct: 927 STWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRE 970
Score = 33.1 bits (74), Expect = 0.72
Identities = 36/124 (29%), Positives = 58/124 (46%), Gaps = 17/124 (13%)
Query: 85 EIALLEKHFLQEELRKLREETNAEMLRQELDR-ERQRRMELEQKVQEVLKARTEEQMAQQ 143
E AL + + LR+ REE + + L R E +RR E E++ QE L + EE+ A+
Sbjct: 791 EEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAK- 849
Query: 144 PPKGQAQASNGAERRSQGLSSRLQKWFYERFGEYVEDFRFQPEENTVETEEPLSARRLTE 203
A+ A+RR + R+++ E R + EE + +E L +R E
Sbjct: 850 ----WAREEEEAQRRLEENRLRMEE----------EAARLRHEEEERKRKE-LEVQRQKE 894
Query: 204 NMRR 207
MR+
Sbjct: 895 LMRQ 898
Score = 32.3 bits (72), Expect = 1.2
Identities = 38/121 (31%), Positives = 58/121 (47%), Gaps = 14/121 (11%)
Query: 87 ALLEKHFLQEELRKLREETNAEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQPPK 146
A LE+ + E+R REE E RQE + RQ+ L ++ +E K R EE++A+
Sbjct: 735 AKLEQERREAEMRAKREEE--ERKRQE-ELRRQQEEILRRQQEEERKRREEEELAR---- 787
Query: 147 GQAQASNGAERRSQGLSSRLQKWFYERFGEYVEDFRFQPEENTVETEEPLSARRLTENMR 206
+ Q +R Q ++ R Q+ ER + E+ + EE E EE RR E +
Sbjct: 788 -RKQEEALRRQREQEIALRRQREEEER--QQQEEALRRLEERRREEEE----RRKQEELL 840
Query: 207 R 207
R
Sbjct: 841 R 841
Score = 31.2 bits (69), Expect = 2.7
Identities = 15/37 (40%), Positives = 25/37 (67%)
Query: 107 AEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQ 143
AE+ + E +RERQ R E ++ +E++KA ++Q QQ
Sbjct: 947 AEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQ 983
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 41.2 bits (95), Expect = 0.003
Identities = 40/137 (29%), Positives = 67/137 (48%), Gaps = 21/137 (15%)
Query: 90 EKHFLQEELRKLREETNAEMLRQELDRERQRRMELE---QKVQEVLKARTEEQMA--QQP 144
E+ QEELR+ +EE +LR++ + ER+RR E E +K +E L+ + E+++A +Q
Sbjct: 753 EERKRQEELRRQQEE----ILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQR 808
Query: 145 PKGQAQASNGA------------ERRSQGLSSRLQKWFYERFGEYVEDFRFQPEENTVET 192
+ + Q A ERR Q R Q+ ++ E+ + + EEN +
Sbjct: 809 EEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRM 868
Query: 193 EEPLSARRLTENMRRLK 209
EE + R E R+ K
Sbjct: 869 EEEAARLRHEEEERKRK 885
Score = 35.0 bits (79), Expect = 0.19
Identities = 32/127 (25%), Positives = 53/127 (41%), Gaps = 15/127 (11%)
Query: 102 REETNAEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQPPKGQAQASNGAERRSQG 161
+E AEM + + ER+R+ EL ++ +E+L+ + EE+ + R +
Sbjct: 739 QERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKR--------------REEEE 784
Query: 162 LSSRLQKWFYERFGEYVEDFRFQPEENTVETEEPLSARRLTENMRRLKRGAKPVTNFVKN 221
L+ R Q+ R E R Q EE + +E + RRL E R + K K
Sbjct: 785 LARRKQEEALRRQREQEIALRRQREEEERQQQEE-ALRRLEERRREEEERRKQEELLRKQ 843
Query: 222 LSALSDW 228
+ W
Sbjct: 844 EEEAAKW 850
Score = 33.9 bits (76), Expect = 0.42
Identities = 33/104 (31%), Positives = 50/104 (48%), Gaps = 11/104 (10%)
Query: 94 LQEELRKLREETNAEMLRQELDRERQRR-MELEQKVQEVLKARTEEQMAQQPPKGQ---- 148
++EE +LR E E R+EL+ +RQ+ M Q+ QE L+ ++Q QQ + +
Sbjct: 868 MEEEAARLRHEEE-ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSS 926
Query: 149 ---AQASNGAERRSQGLSS--RLQKWFYERFGEYVEDFRFQPEE 187
Q SN +SQ S +QK ER + E+ R Q E
Sbjct: 927 STWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRE 970
Score = 33.1 bits (74), Expect = 0.72
Identities = 36/124 (29%), Positives = 58/124 (46%), Gaps = 17/124 (13%)
Query: 85 EIALLEKHFLQEELRKLREETNAEMLRQELDR-ERQRRMELEQKVQEVLKARTEEQMAQQ 143
E AL + + LR+ REE + + L R E +RR E E++ QE L + EE+ A+
Sbjct: 791 EEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAK- 849
Query: 144 PPKGQAQASNGAERRSQGLSSRLQKWFYERFGEYVEDFRFQPEENTVETEEPLSARRLTE 203
A+ A+RR + R+++ E R + EE + +E L +R E
Sbjct: 850 ----WAREEEEAQRRLEENRLRMEE----------EAARLRHEEEERKRKE-LEVQRQKE 894
Query: 204 NMRR 207
MR+
Sbjct: 895 LMRQ 898
Score = 32.3 bits (72), Expect = 1.2
Identities = 38/121 (31%), Positives = 58/121 (47%), Gaps = 14/121 (11%)
Query: 87 ALLEKHFLQEELRKLREETNAEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQPPK 146
A LE+ + E+R REE E RQE + RQ+ L ++ +E K R EE++A+
Sbjct: 735 AKLEQERREAEMRAKREEE--ERKRQE-ELRRQQEEILRRQQEEERKRREEEELAR---- 787
Query: 147 GQAQASNGAERRSQGLSSRLQKWFYERFGEYVEDFRFQPEENTVETEEPLSARRLTENMR 206
+ Q +R Q ++ R Q+ ER + E+ + EE E EE RR E +
Sbjct: 788 -RKQEEALRRQREQEIALRRQREEEER--QQQEEALRRLEERRREEEE----RRKQEELL 840
Query: 207 R 207
R
Sbjct: 841 R 841
Score = 31.2 bits (69), Expect = 2.7
Identities = 15/37 (40%), Positives = 25/37 (67%)
Query: 107 AEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQ 143
AE+ + E +RERQ R E ++ +E++KA ++Q QQ
Sbjct: 947 AEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQ 983
>gi|112789536 troponin T3, skeletal, fast isoform 3 [Homo sapiens]
Length = 250
Score = 41.2 bits (95), Expect = 0.003
Identities = 42/181 (23%), Positives = 79/181 (43%), Gaps = 26/181 (14%)
Query: 46 RDSEELRDPAGPGTLIMATGVQDFNRTEFDRLNEIKGHLEI----ALLEKHF-------- 93
++ EE+++ P + A + + + +FD + + + + ++ AL++ HF
Sbjct: 20 QEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEE 79
Query: 94 ----LQEELRKLR-EETNAEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQPPKGQ 148
L+E + K R E + +R E +RERQ R+ E KAR EE+ A++ +
Sbjct: 80 ELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEE-------KARREEEDAKRRAEDD 132
Query: 149 AQASNGAERRSQGLSSRLQKWFYERFGEYVEDFRFQPEENTVETEEPLSARRLTENMRRL 208
+ SS L K +R + + R ++ E +PL+ L E+ R
Sbjct: 133 LKKKKALSSMGANYSSYLAKADQKRGKK--QTAREMKKKILAERRKPLNIDHLGEDKLRD 190
Query: 209 K 209
K
Sbjct: 191 K 191
>gi|112789541 troponin T3, skeletal, fast isoform 4 [Homo sapiens]
Length = 250
Score = 41.2 bits (95), Expect = 0.003
Identities = 42/181 (23%), Positives = 79/181 (43%), Gaps = 26/181 (14%)
Query: 46 RDSEELRDPAGPGTLIMATGVQDFNRTEFDRLNEIKGHLEI----ALLEKHF-------- 93
++ EE+++ P + A + + + +FD + + + + ++ AL++ HF
Sbjct: 20 QEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEE 79
Query: 94 ----LQEELRKLR-EETNAEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQPPKGQ 148
L+E + K R E + +R E +RERQ R+ E KAR EE+ A++ +
Sbjct: 80 ELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEE-------KARREEEDAKRRAEDD 132
Query: 149 AQASNGAERRSQGLSSRLQKWFYERFGEYVEDFRFQPEENTVETEEPLSARRLTENMRRL 208
+ SS L K +R + + R ++ E +PL+ L E+ R
Sbjct: 133 LKKKKALSSMGANYSSYLAKADQKRGKK--QTAREMKKKILAERRKPLNIDHLGEDKLRD 190
Query: 209 K 209
K
Sbjct: 191 K 191
>gi|68077168 DnaJ homology subfamily A member 5 isoform 1 [Homo
sapiens]
Length = 576
Score = 40.8 bits (94), Expect = 0.003
Identities = 31/113 (27%), Positives = 57/113 (50%), Gaps = 8/113 (7%)
Query: 90 EKHFLQEELRKLREETNAE---MLRQELD--RERQRRMELEQKV---QEVLKARTEEQMA 141
EK +++E +K+R++ E ++RQ + R+R +R++ +K+ Q KAR E+M
Sbjct: 180 EKRAMEKENKKIRDKARKEKNELVRQLVAFIRKRDKRVQAHRKLVEEQNAEKARKAEEMR 239
Query: 142 QQPPKGQAQASNGAERRSQGLSSRLQKWFYERFGEYVEDFRFQPEENTVETEE 194
+Q QA+ +S + L+K E Y ++F +EN +E E
Sbjct: 240 RQQKLKQAKLVEQYREQSWMTMANLEKELQEMEARYEKEFGDGSDENEMEEHE 292
Score = 30.0 bits (66), Expect = 6.1
Identities = 29/118 (24%), Positives = 55/118 (46%), Gaps = 14/118 (11%)
Query: 78 NEIKGHLEIALLEKHFLQEELRKLREETNAEMLRQELDRERQRRMELEQKVQEVLKARTE 137
NE+ L + ++ + RKL EE NAE R+ + RQ++++ +A+
Sbjct: 200 NELVRQLVAFIRKRDKRVQAHRKLVEEQNAEKARKAEEMRRQQKLK---------QAKLV 250
Query: 138 EQMAQQPPKGQAQASNGAERRSQGLSSRLQKWFYERFGE-YVEDFRFQPEENTVETEE 194
EQ +Q A E+ Q + +R +K F + E +E+ + EE+ +++E
Sbjct: 251 EQYREQSWMTMA----NLEKELQEMEARYEKEFGDGSDENEMEEHELKDEEDGKDSDE 304
>gi|68077166 DnaJ homology subfamily A member 5 isoform 2 [Homo
sapiens]
Length = 531
Score = 40.8 bits (94), Expect = 0.003
Identities = 31/113 (27%), Positives = 57/113 (50%), Gaps = 8/113 (7%)
Query: 90 EKHFLQEELRKLREETNAE---MLRQELD--RERQRRMELEQKV---QEVLKARTEEQMA 141
EK +++E +K+R++ E ++RQ + R+R +R++ +K+ Q KAR E+M
Sbjct: 180 EKRAMEKENKKIRDKARKEKNELVRQLVAFIRKRDKRVQAHRKLVEEQNAEKARKAEEMR 239
Query: 142 QQPPKGQAQASNGAERRSQGLSSRLQKWFYERFGEYVEDFRFQPEENTVETEE 194
+Q QA+ +S + L+K E Y ++F +EN +E E
Sbjct: 240 RQQKLKQAKLVEQYREQSWMTMANLEKELQEMEARYEKEFGDGSDENEMEEHE 292
Score = 30.0 bits (66), Expect = 6.1
Identities = 29/118 (24%), Positives = 55/118 (46%), Gaps = 14/118 (11%)
Query: 78 NEIKGHLEIALLEKHFLQEELRKLREETNAEMLRQELDRERQRRMELEQKVQEVLKARTE 137
NE+ L + ++ + RKL EE NAE R+ + RQ++++ +A+
Sbjct: 200 NELVRQLVAFIRKRDKRVQAHRKLVEEQNAEKARKAEEMRRQQKLK---------QAKLV 250
Query: 138 EQMAQQPPKGQAQASNGAERRSQGLSSRLQKWFYERFGE-YVEDFRFQPEENTVETEE 194
EQ +Q A E+ Q + +R +K F + E +E+ + EE+ +++E
Sbjct: 251 EQYREQSWMTMA----NLEKELQEMEARYEKEFGDGSDENEMEEHELKDEEDGKDSDE 304
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 40.4 bits (93), Expect = 0.004
Identities = 35/123 (28%), Positives = 54/123 (43%), Gaps = 8/123 (6%)
Query: 90 EKHFLQEELRKLREETNAEMLRQELDRERQRRMELEQKV--QEVLKARTEEQMAQQPPKG 147
EK + QE++ K +E + QE RE + E E+K+ +E + EE+M +Q K
Sbjct: 684 EKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKM 743
Query: 148 QAQASNGAERRSQGLSSRLQKWFYERFGEYVEDF----RFQPEENTVETEEPLSARRLTE 203
Q Q E+ + + W +R E E + Q +E E EE + R E
Sbjct: 744 QEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKM--RDQEE 801
Query: 204 NMR 206
MR
Sbjct: 802 KMR 804
Score = 38.1 bits (87), Expect = 0.022
Identities = 33/117 (28%), Positives = 55/117 (47%), Gaps = 17/117 (14%)
Query: 85 EIALLEKHFLQEELRKLREETNAEMLRQELDRERQRRM-ELEQKVQEVLKARTEEQMAQQ 143
E + E+ ++E +K+REE +E+ RE++ +M E E+K+QE EE+M +Q
Sbjct: 582 EEKMREEERMREREKKMREE-------EEMMREQEEKMQEQEEKMQE-----QEEKMWEQ 629
Query: 144 PPKGQAQASNGAERRSQGLSSRLQKWFYERFGEYVEDF----RFQPEENTVETEEPL 196
K Q Q E+ + + W +R E E + Q +E E EE +
Sbjct: 630 EEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKI 686
Score = 37.7 bits (86), Expect = 0.029
Identities = 28/116 (24%), Positives = 54/116 (46%), Gaps = 1/116 (0%)
Query: 94 LQEELRKLREETNAEMLRQELDRERQRRMELEQKV-QEVLKARTEEQMAQQPPKGQAQAS 152
++E+ +K+R++ + E RE++ RM ++K+ ++V K R E++M +Q K + Q
Sbjct: 385 MREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEE 444
Query: 153 NGAERRSQGLSSRLQKWFYERFGEYVEDFRFQPEENTVETEEPLSARRLTENMRRL 208
E + + E E E + Q E + E+ +RL E +L
Sbjct: 445 KMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKL 500
Score = 33.1 bits (74), Expect = 0.72
Identities = 34/140 (24%), Positives = 66/140 (47%), Gaps = 12/140 (8%)
Query: 75 DRLNEIKGHL----EIALLEKHFLQEELRKLREETNAEMLRQELDRERQRRMELEQKVQE 130
+RL E +G + E ++ L+E+ ++LRE+ ++EL + ++ E E+K+ E
Sbjct: 300 ERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWE 359
Query: 131 VLKARTEEQMAQQPPKGQAQASNGAERRSQGLSSRLQKWFYERFGEYVEDFRFQPEENTV 190
EE+M +Q K Q E+ Q + + QK + + +D R + +E +
Sbjct: 360 -----QEEKMREQEEKMWRQEERLWEQEKQ-MREQEQKMRDQEERMWEQDERLREKEERM 413
Query: 191 ETEEPLSARRLTENMRRLKR 210
+E + + E MR K+
Sbjct: 414 REQEKMWEQ--VEKMREEKK 431
Score = 32.0 bits (71), Expect = 1.6
Identities = 32/124 (25%), Positives = 57/124 (45%), Gaps = 22/124 (17%)
Query: 85 EIALLEKHFLQEELRKLREETNAEMLRQELDRERQRRMELEQKVQEVLKAR--------T 136
E + E+ + E++ K+REE +++ + ++ + E+K+QE + R
Sbjct: 410 EERMREQEKMWEQVEKMREE-------KKMQEQEKKTRDQEEKMQEEERIREREKKMREE 462
Query: 137 EEQMAQQPPKGQAQASNGAER-----RSQGLSSRLQK-WFYERFGEYVEDFRFQPEENTV 190
EE M +Q K Q Q N E+ + Q L + +K W E+ E E ++ EE
Sbjct: 463 EETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKI-WEQEEKIR 521
Query: 191 ETEE 194
+ EE
Sbjct: 522 DQEE 525
Score = 30.8 bits (68), Expect = 3.6
Identities = 30/131 (22%), Positives = 61/131 (46%), Gaps = 15/131 (11%)
Query: 94 LQEELRKLREETNAEMLRQELDRERQRRMELEQKV--QEVLKARTEEQMAQQPP--KGQA 149
L+E+ ++LRE+ +++ + ++ E E+K+ QE R EE++ +Q + Q
Sbjct: 330 LREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQE 389
Query: 150 QASNGAERRSQGLSSRL---------QKWFYERFGEYVEDFRFQPEE-NTVETEEPL-SA 198
Q E R RL Q+ +E+ + E+ + Q +E T + EE +
Sbjct: 390 QKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEE 449
Query: 199 RRLTENMRRLK 209
R+ E ++++
Sbjct: 450 ERIREREKKMR 460
Score = 30.8 bits (68), Expect = 3.6
Identities = 29/139 (20%), Positives = 61/139 (43%), Gaps = 11/139 (7%)
Query: 62 MATGVQDFNRTEFDRLNEIKGHLEIALLEKHFLQEELRKLREETNAEMLRQELDRERQRR 121
M Q+ + +D+ +++ + EK +EE +E + +++ + ++
Sbjct: 567 MEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKM 626
Query: 122 MELEQKVQEVLKARTEEQMAQQPPKGQAQASNGAERRSQGLSSRLQK-WFYERFGEYVED 180
E E+K+QE EE+M +Q K Q E+ Q L + +K W +E+ E
Sbjct: 627 WEQEEKMQE-----QEEKMWEQEEKMWEQEEKMWEQ--QRLPEQKEKLWEHEKM---QEQ 676
Query: 181 FRFQPEENTVETEEPLSAR 199
+ Q +E + +E + +
Sbjct: 677 EKMQEQEEKIWEQEKMEKK 695
>gi|4505101 microtubule-associated protein 7 [Homo sapiens]
Length = 749
Score = 40.4 bits (93), Expect = 0.004
Identities = 41/134 (30%), Positives = 61/134 (45%), Gaps = 15/134 (11%)
Query: 88 LLEKHFLQEELRKLREETNAEMLRQELDRERQRRMELEQKVQEVLKARTEEQM----AQQ 143
L EK L E R+ E R++ + ERQ+R EL Q+V E R EE+ A+Q
Sbjct: 483 LAEKRRLAREQREKEERER----REQEELERQKREELAQRVAEERTTRREEESRRLEAEQ 538
Query: 144 PPKGQAQASNGAERRS-----QGLSSRLQKWFYERFGEYVEDFRFQPEENTVETEEPLSA 198
+ + Q AE R+ + ++ QK R E E R + E++ E+
Sbjct: 539 AREKEEQLQRQAEERALREREEAERAQRQKEEEARVREEAERVRQEREKHFQREEQERLE 598
Query: 199 R--RLTENMRRLKR 210
R RL E M+R +R
Sbjct: 599 RKKRLEEIMKRTRR 612
Score = 35.0 bits (79), Expect = 0.19
Identities = 31/114 (27%), Positives = 53/114 (46%), Gaps = 11/114 (9%)
Query: 103 EETNAEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQPPKGQAQASNGAERRSQGL 162
E T ++ L RE++ + E E++ QE L+ + E++AQ+ AE R+
Sbjct: 478 EATRLLAEKRRLAREQREKEERERREQEELERQKREELAQRV----------AEERTTRR 527
Query: 163 SSRLQKWFYERFGEYVEDFRFQPEENTV-ETEEPLSARRLTENMRRLKRGAKPV 215
++ E+ E E + Q EE + E EE A+R E R++ A+ V
Sbjct: 528 EEESRRLEAEQAREKEEQLQRQAEERALREREEAERAQRQKEEEARVREEAERV 581
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 40.4 bits (93), Expect = 0.004
Identities = 41/143 (28%), Positives = 62/143 (43%), Gaps = 24/143 (16%)
Query: 79 EIKGHLEIALLEKHFLQEELRKL---------REETNAEMLRQELDRERQRRMELEQKVQ 129
E + H E+ +K QE LRK RE+ E R+E +R Q R E E++ Q
Sbjct: 656 EERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQ 715
Query: 130 EVLKARTEEQMAQQPPKGQAQASNGAERRSQGLSSRLQKWFYERFGEYVEDFRFQPEENT 189
E A E + Q+ + QA + R + L RLQK +R E E+
Sbjct: 716 ERQLAEQERRREQE----RLQAERELQEREKAL--RLQKEQLQRELE---------EKKK 760
Query: 190 VETEEPLSARRLTENMRRLKRGA 212
E ++ L+ R+L E + + A
Sbjct: 761 KEEQQRLAERQLQEEQEKKAKEA 783
Score = 36.6 bits (83), Expect = 0.065
Identities = 37/155 (23%), Positives = 68/155 (43%), Gaps = 39/155 (25%)
Query: 95 QEELRKLREETNAEMLR-QELDRERQRRME-----LEQKVQEVLKAR------------- 135
++ L LR + AE LR Q+++ +++RR+E E+++++VL+AR
Sbjct: 539 RQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQ 598
Query: 136 ---------------TEEQMAQQPPKGQAQASNGAE---RRSQGLSSRLQKWFYERFGE- 176
EE++A++ K +A A E RR Q +R +W + E
Sbjct: 599 IEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEER 658
Query: 177 -YVEDFRFQPEENTVETEEPLSARRLTENMRRLKR 210
+ E + + EE + A+RL E + +R
Sbjct: 659 RHQELLQKKKEEEQERLRKAAEAKRLAEQREQERR 693
Score = 30.8 bits (68), Expect = 3.6
Identities = 25/94 (26%), Positives = 46/94 (48%), Gaps = 9/94 (9%)
Query: 71 RTEFDRLNEIKGHLEIALLEKHFLQEELRKLREETNAEMLRQELDRERQRRM-------E 123
R E +R + + E E+ ++E R+ +E AE QE RE+ R+ E
Sbjct: 697 RREQERREQERREQERREQERQLAEQERRREQERLQAERELQE--REKALRLQKEQLQRE 754
Query: 124 LEQKVQEVLKARTEEQMAQQPPKGQAQASNGAER 157
LE+K ++ + R E+ Q+ + +A+ + GA +
Sbjct: 755 LEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASK 788
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 40.4 bits (93), Expect = 0.004
Identities = 41/143 (28%), Positives = 62/143 (43%), Gaps = 24/143 (16%)
Query: 79 EIKGHLEIALLEKHFLQEELRKL---------REETNAEMLRQELDRERQRRMELEQKVQ 129
E + H E+ +K QE LRK RE+ E R+E +R Q R E E++ Q
Sbjct: 652 EERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQ 711
Query: 130 EVLKARTEEQMAQQPPKGQAQASNGAERRSQGLSSRLQKWFYERFGEYVEDFRFQPEENT 189
E A E + Q+ + QA + R + L RLQK +R E E+
Sbjct: 712 ERQLAEQERRREQE----RLQAERELQEREKAL--RLQKEQLQRELE---------EKKK 756
Query: 190 VETEEPLSARRLTENMRRLKRGA 212
E ++ L+ R+L E + + A
Sbjct: 757 KEEQQRLAERQLQEEQEKKAKEA 779
Score = 37.7 bits (86), Expect = 0.029
Identities = 40/170 (23%), Positives = 74/170 (43%), Gaps = 39/170 (22%)
Query: 80 IKGHLEIALLEKHFLQEELRKLREETNAEMLR-QELDRERQRRME-----LEQKVQEVLK 133
IK + + + K ++ L LR + AE LR Q+++ +++RR+E E+++++VL+
Sbjct: 520 IKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQ 579
Query: 134 AR----------------------------TEEQMAQQPPKGQAQASNGAE---RRSQGL 162
AR EE++A++ K +A A E RR Q
Sbjct: 580 ARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEE 639
Query: 163 SSRLQKWFYERFGE--YVEDFRFQPEENTVETEEPLSARRLTENMRRLKR 210
+R +W + E + E + + EE + A+RL E + +R
Sbjct: 640 EARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERR 689
Score = 30.8 bits (68), Expect = 3.6
Identities = 25/94 (26%), Positives = 46/94 (48%), Gaps = 9/94 (9%)
Query: 71 RTEFDRLNEIKGHLEIALLEKHFLQEELRKLREETNAEMLRQELDRERQRRM-------E 123
R E +R + + E E+ ++E R+ +E AE QE RE+ R+ E
Sbjct: 693 RREQERREQERREQERREQERQLAEQERRREQERLQAERELQE--REKALRLQKEQLQRE 750
Query: 124 LEQKVQEVLKARTEEQMAQQPPKGQAQASNGAER 157
LE+K ++ + R E+ Q+ + +A+ + GA +
Sbjct: 751 LEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASK 784
>gi|48255883 troponin T type 2, cardiac isoform 4 [Homo sapiens]
Length = 282
Score = 39.7 bits (91), Expect = 0.008
Identities = 51/233 (21%), Positives = 95/233 (40%), Gaps = 42/233 (18%)
Query: 23 ESPNASDTECSDEIPLKVPRTSPRDSEELRDPAGPGTL-------------IMATGVQDF 69
E A++ + E + R + EE A G + ++ + D
Sbjct: 18 EQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDG 77
Query: 70 NRTEFDRLNEIKGHLEI----ALLEKHFLQEELRKLREETNAEMLRQELDRERQRRMELE 125
R +FD ++ + ++ AL+E HF E RK +EE L+ ++R R R E +
Sbjct: 78 ERVDFDDIHRKRMEKDLNELQALIEAHF---ENRK-KEEEELVSLKDRIERRRAERAEQQ 133
Query: 126 QKVQEVLKAR----TEEQMAQQPPKGQAQASNGAERRSQGLSSRLQKWFYERFGEYVEDF 181
+ E K R EE+ ++ + + +A + A R+ + LS+ + FG Y++
Sbjct: 134 RIRNEREKERQNRLAEERARREEEENRRKAEDEA-RKKKALSNMM------HFGGYIQKA 186
Query: 182 RFQPEENTVETEEPLSARRLTE----------NMRRLKRGAKPVTNFVKNLSA 224
+ + + +TE + L E N +L+ AK + + NL A
Sbjct: 187 QTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEA 239
>gi|239752551 PREDICTED: hypothetical protein [Homo sapiens]
Length = 238
Score = 39.7 bits (91), Expect = 0.008
Identities = 31/125 (24%), Positives = 62/125 (49%), Gaps = 14/125 (11%)
Query: 90 EKHFLQEELRKLREETNAEMLRQELDRERQRRM-ELEQKVQEVLKARTEEQMAQQPPKGQ 148
E+ ++E +K+REE +E+ RE++ +M E E+K++E EE+M +Q K Q
Sbjct: 3 EEERMREREKKMREE-------EEMMREQEEKMQEQEEKMRE-----QEEKMWEQEEKMQ 50
Query: 149 AQASNGAERRSQGLSSRLQKWFYERFGEYVEDFRFQPEENTVETEEPLSARRLTENMRRL 208
Q E+ + + W +R E E ++ +E E EE + +++ + + ++
Sbjct: 51 EQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKM-WEQDERLREKEERMREQKMWQQVEKM 109
Query: 209 KRGAK 213
+ K
Sbjct: 110 REKKK 114
Score = 33.1 bits (74), Expect = 0.72
Identities = 29/111 (26%), Positives = 51/111 (45%), Gaps = 3/111 (2%)
Query: 85 EIALLEKHFLQEELRKLREETNAEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQP 144
E + E+ L E+ K+ E+ E LR++ +R R+++M + + K EE+M +Q
Sbjct: 67 EEKMWEQQRLPEQKEKMWEQD--ERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQE 124
Query: 145 PKGQAQASNGAERRSQGLSSRLQKWFY-ERFGEYVEDFRFQPEENTVETEE 194
K Q Q E+ + + W E+ E E R Q E+ + E+
Sbjct: 125 EKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEK 175
>gi|118918407 spectrin repeat containing, nuclear envelope 2 isoform 5
[Homo sapiens]
Length = 6907
Score = 39.3 bits (90), Expect = 0.010
Identities = 37/151 (24%), Positives = 65/151 (43%), Gaps = 17/151 (11%)
Query: 85 EIALLEKHFLQEELRKLREETNAEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQP 144
E L + + E LR+L EE ++ +QE+ R + + EQK++ +LK +E M QP
Sbjct: 986 EGCLYQLNHHMEVLRELCEELPSQKSQQEVKRLLK---DYEQKIERLLKCASEIHMTLQP 1042
Query: 145 PKGQAQASNGAERRSQGLSSRLQKWFYERFGEYVEDFRFQPEENTVETE---EPLSARRL 201
G + G S+ R G+ + F +N TE EP L
Sbjct: 1043 TAGGTSKNEGTITTSE-----------NRGGDPHSEAPFAKSDNQPSTEKAMEPTMKFSL 1091
Query: 202 TENMRRLKRGAKPVTNFVKNLSALSDWYSVY 232
+R L+ + ++ ++++L + Y Y
Sbjct: 1092 ASVLRPLQEESIMEKDYSASINSLLERYDTY 1122
>gi|118918403 spectrin repeat containing, nuclear envelope 2 isoform 1
[Homo sapiens]
Length = 6885
Score = 39.3 bits (90), Expect = 0.010
Identities = 37/151 (24%), Positives = 65/151 (43%), Gaps = 17/151 (11%)
Query: 85 EIALLEKHFLQEELRKLREETNAEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQP 144
E L + + E LR+L EE ++ +QE+ R + + EQK++ +LK +E M QP
Sbjct: 986 EGCLYQLNHHMEVLRELCEELPSQKSQQEVKRLLK---DYEQKIERLLKCASEIHMTLQP 1042
Query: 145 PKGQAQASNGAERRSQGLSSRLQKWFYERFGEYVEDFRFQPEENTVETE---EPLSARRL 201
G + G S+ R G+ + F +N TE EP L
Sbjct: 1043 TAGGTSKNEGTITTSE-----------NRGGDPHSEAPFAKSDNQPSTEKAMEPTMKFSL 1091
Query: 202 TENMRRLKRGAKPVTNFVKNLSALSDWYSVY 232
+R L+ + ++ ++++L + Y Y
Sbjct: 1092 ASVLRPLQEESIMEKDYSASINSLLERYDTY 1122
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,824,389
Number of Sequences: 37866
Number of extensions: 983858
Number of successful extensions: 6913
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 95
Number of HSP's successfully gapped in prelim test: 355
Number of HSP's that attempted gapping in prelim test: 4924
Number of HSP's gapped (non-prelim): 1612
length of query: 578
length of database: 18,247,518
effective HSP length: 108
effective length of query: 470
effective length of database: 14,157,990
effective search space: 6654255300
effective search space used: 6654255300
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.