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Search of human proteins with 66932984
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|66932984 folylpolyglutamate synthase isoform a precursor
[Homo sapiens]
(587 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|66932984 folylpolyglutamate synthase isoform a precursor [Hom... 1198 0.0
gi|66932990 folylpolyglutamate synthase isoform b [Homo sapiens] 1103 0.0
gi|224994221 SH3-domain binding protein 2 isoform b [Homo sapiens] 35 0.15
gi|224994219 SH3-domain binding protein 2 isoform c [Homo sapiens] 35 0.15
gi|170014705 SH3-domain binding protein 2 isoform a [Homo sapiens] 35 0.15
gi|170014703 SH3-domain binding protein 2 isoform a [Homo sapiens] 35 0.15
gi|121114296 caudal type homeobox 1 [Homo sapiens] 35 0.19
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 33 0.56
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 33 0.56
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap... 33 0.56
gi|38201702 telomerase reverse transcriptase isoform 2 [Homo sap... 32 1.2
gi|109633031 telomerase reverse transcriptase isoform 1 [Homo sa... 32 1.2
gi|41352697 centromere protein I [Homo sapiens] 32 1.6
gi|169207217 PREDICTED: zinc finger homeobox 2 [Homo sapiens] 32 2.1
gi|169207592 PREDICTED: zinc finger homeobox 2 [Homo sapiens] 32 2.1
gi|169207014 PREDICTED: zinc finger homeobox 2 [Homo sapiens] 32 2.1
gi|133892686 hypothetical protein LOC727830 [Homo sapiens] 32 2.1
gi|223468617 family with sequence similarity 75, member C1 [Homo... 31 2.8
gi|223633941 hypothetical protein LOC389730 [Homo sapiens] 31 2.8
gi|91206406 hypothetical protein LOC642265 [Homo sapiens] 31 2.8
gi|169174618 PREDICTED: family with sequence similarity 75, memb... 31 2.8
gi|239743732 PREDICTED: family with sequence similarity 75, memb... 31 2.8
gi|66529407 tensin [Homo sapiens] 31 2.8
gi|153791826 hypothetical protein LOC26165 [Homo sapiens] 31 2.8
gi|167234417 hypothetical protein LOC441054 [Homo sapiens] 31 2.8
gi|146231958 hypothetical protein LOC647060 [Homo sapiens] 31 2.8
gi|165377334 hypothetical protein LOC727905 [Homo sapiens] 31 2.8
gi|238859651 pleckstrin homology domain containing family A memb... 30 4.7
gi|126507091 LATS, large tumor suppressor, homolog 2 [Homo sapiens] 30 4.7
gi|4885187 distal-less homeobox 5 [Homo sapiens] 30 6.2
>gi|66932984 folylpolyglutamate synthase isoform a precursor [Homo
sapiens]
Length = 587
Score = 1198 bits (3100), Expect = 0.0
Identities = 587/587 (100%), Positives = 587/587 (100%)
Query: 1 MSRARSHLRAALFLAAASARGITTQVAARRGLSAWPVPQEPSMEYQDAVRMLNTLQTNAG 60
MSRARSHLRAALFLAAASARGITTQVAARRGLSAWPVPQEPSMEYQDAVRMLNTLQTNAG
Sbjct: 1 MSRARSHLRAALFLAAASARGITTQVAARRGLSAWPVPQEPSMEYQDAVRMLNTLQTNAG 60
Query: 61 YLEQVKRQRGDPQTQLEAMELYLARSGLQVEDLDRLNIIHVTGTKGKGSTCAFTECILRS 120
YLEQVKRQRGDPQTQLEAMELYLARSGLQVEDLDRLNIIHVTGTKGKGSTCAFTECILRS
Sbjct: 61 YLEQVKRQRGDPQTQLEAMELYLARSGLQVEDLDRLNIIHVTGTKGKGSTCAFTECILRS 120
Query: 121 YGLKTGFFSSPHLVQVRERIRINGQPISPELFTKYFWRLYHRLEETKDGSCVSMPPYFRF 180
YGLKTGFFSSPHLVQVRERIRINGQPISPELFTKYFWRLYHRLEETKDGSCVSMPPYFRF
Sbjct: 121 YGLKTGFFSSPHLVQVRERIRINGQPISPELFTKYFWRLYHRLEETKDGSCVSMPPYFRF 180
Query: 181 LTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGVSSLGIDHTSLLGDTVEKIA 240
LTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGVSSLGIDHTSLLGDTVEKIA
Sbjct: 181 LTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGVSSLGIDHTSLLGDTVEKIA 240
Query: 241 WQKGGIFKQGVPAFTVLQPEGPLAVLRDRAQQISCPLYLCPMLEALEEGGPPLTLGLEGE 300
WQKGGIFKQGVPAFTVLQPEGPLAVLRDRAQQISCPLYLCPMLEALEEGGPPLTLGLEGE
Sbjct: 241 WQKGGIFKQGVPAFTVLQPEGPLAVLRDRAQQISCPLYLCPMLEALEEGGPPLTLGLEGE 300
Query: 301 HQRSNAALALQLAHCWLQRQDRHGAGEPKASRPGLLWQLPLAPVFQPTSHMRLGLRNTEW 360
HQRSNAALALQLAHCWLQRQDRHGAGEPKASRPGLLWQLPLAPVFQPTSHMRLGLRNTEW
Sbjct: 301 HQRSNAALALQLAHCWLQRQDRHGAGEPKASRPGLLWQLPLAPVFQPTSHMRLGLRNTEW 360
Query: 361 PGRTQVLRRGPLTWYLDGAHTASSAQACVRWFRQALQGRERPSGGPEVRVLLFNATGDRD 420
PGRTQVLRRGPLTWYLDGAHTASSAQACVRWFRQALQGRERPSGGPEVRVLLFNATGDRD
Sbjct: 361 PGRTQVLRRGPLTWYLDGAHTASSAQACVRWFRQALQGRERPSGGPEVRVLLFNATGDRD 420
Query: 421 PAALLKLLQPCQFDYAVFCPNLTEVSSTGNADQQNFTVTLDQVLLRCLEHQQHWNHLDEE 480
PAALLKLLQPCQFDYAVFCPNLTEVSSTGNADQQNFTVTLDQVLLRCLEHQQHWNHLDEE
Sbjct: 421 PAALLKLLQPCQFDYAVFCPNLTEVSSTGNADQQNFTVTLDQVLLRCLEHQQHWNHLDEE 480
Query: 481 QASPDLWSAPSPEPGGSASLLLAPHPPHTCSASSLVFSCISHALQWISQGRDPIFQPPSP 540
QASPDLWSAPSPEPGGSASLLLAPHPPHTCSASSLVFSCISHALQWISQGRDPIFQPPSP
Sbjct: 481 QASPDLWSAPSPEPGGSASLLLAPHPPHTCSASSLVFSCISHALQWISQGRDPIFQPPSP 540
Query: 541 PKGLLTHPVAHSGASILREAAAIHVLVTGSLHLVGGVLKLLEPALSQ 587
PKGLLTHPVAHSGASILREAAAIHVLVTGSLHLVGGVLKLLEPALSQ
Sbjct: 541 PKGLLTHPVAHSGASILREAAAIHVLVTGSLHLVGGVLKLLEPALSQ 587
>gi|66932990 folylpolyglutamate synthase isoform b [Homo sapiens]
Length = 537
Score = 1103 bits (2853), Expect = 0.0
Identities = 537/537 (100%), Positives = 537/537 (100%)
Query: 51 MLNTLQTNAGYLEQVKRQRGDPQTQLEAMELYLARSGLQVEDLDRLNIIHVTGTKGKGST 110
MLNTLQTNAGYLEQVKRQRGDPQTQLEAMELYLARSGLQVEDLDRLNIIHVTGTKGKGST
Sbjct: 1 MLNTLQTNAGYLEQVKRQRGDPQTQLEAMELYLARSGLQVEDLDRLNIIHVTGTKGKGST 60
Query: 111 CAFTECILRSYGLKTGFFSSPHLVQVRERIRINGQPISPELFTKYFWRLYHRLEETKDGS 170
CAFTECILRSYGLKTGFFSSPHLVQVRERIRINGQPISPELFTKYFWRLYHRLEETKDGS
Sbjct: 61 CAFTECILRSYGLKTGFFSSPHLVQVRERIRINGQPISPELFTKYFWRLYHRLEETKDGS 120
Query: 171 CVSMPPYFRFLTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGVSSLGIDHTS 230
CVSMPPYFRFLTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGVSSLGIDHTS
Sbjct: 121 CVSMPPYFRFLTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGVSSLGIDHTS 180
Query: 231 LLGDTVEKIAWQKGGIFKQGVPAFTVLQPEGPLAVLRDRAQQISCPLYLCPMLEALEEGG 290
LLGDTVEKIAWQKGGIFKQGVPAFTVLQPEGPLAVLRDRAQQISCPLYLCPMLEALEEGG
Sbjct: 181 LLGDTVEKIAWQKGGIFKQGVPAFTVLQPEGPLAVLRDRAQQISCPLYLCPMLEALEEGG 240
Query: 291 PPLTLGLEGEHQRSNAALALQLAHCWLQRQDRHGAGEPKASRPGLLWQLPLAPVFQPTSH 350
PPLTLGLEGEHQRSNAALALQLAHCWLQRQDRHGAGEPKASRPGLLWQLPLAPVFQPTSH
Sbjct: 241 PPLTLGLEGEHQRSNAALALQLAHCWLQRQDRHGAGEPKASRPGLLWQLPLAPVFQPTSH 300
Query: 351 MRLGLRNTEWPGRTQVLRRGPLTWYLDGAHTASSAQACVRWFRQALQGRERPSGGPEVRV 410
MRLGLRNTEWPGRTQVLRRGPLTWYLDGAHTASSAQACVRWFRQALQGRERPSGGPEVRV
Sbjct: 301 MRLGLRNTEWPGRTQVLRRGPLTWYLDGAHTASSAQACVRWFRQALQGRERPSGGPEVRV 360
Query: 411 LLFNATGDRDPAALLKLLQPCQFDYAVFCPNLTEVSSTGNADQQNFTVTLDQVLLRCLEH 470
LLFNATGDRDPAALLKLLQPCQFDYAVFCPNLTEVSSTGNADQQNFTVTLDQVLLRCLEH
Sbjct: 361 LLFNATGDRDPAALLKLLQPCQFDYAVFCPNLTEVSSTGNADQQNFTVTLDQVLLRCLEH 420
Query: 471 QQHWNHLDEEQASPDLWSAPSPEPGGSASLLLAPHPPHTCSASSLVFSCISHALQWISQG 530
QQHWNHLDEEQASPDLWSAPSPEPGGSASLLLAPHPPHTCSASSLVFSCISHALQWISQG
Sbjct: 421 QQHWNHLDEEQASPDLWSAPSPEPGGSASLLLAPHPPHTCSASSLVFSCISHALQWISQG 480
Query: 531 RDPIFQPPSPPKGLLTHPVAHSGASILREAAAIHVLVTGSLHLVGGVLKLLEPALSQ 587
RDPIFQPPSPPKGLLTHPVAHSGASILREAAAIHVLVTGSLHLVGGVLKLLEPALSQ
Sbjct: 481 RDPIFQPPSPPKGLLTHPVAHSGASILREAAAIHVLVTGSLHLVGGVLKLLEPALSQ 537
>gi|224994221 SH3-domain binding protein 2 isoform b [Homo sapiens]
Length = 618
Score = 35.4 bits (80), Expect = 0.15
Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 10/78 (12%)
Query: 472 QHWNHLDEEQA--SPDLWSAPSPEPGGSASLLLAPH---PPHTCSASSLVFSCISHALQW 526
+ + H DE+ + PD SPEPG L+ P PP + FS + A +
Sbjct: 229 EDYEHDDEDDSYLEPD-----SPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSF 283
Query: 527 ISQGRDPIFQPPSPPKGL 544
S+G P+ PP P GL
Sbjct: 284 TSKGPGPLLPPPPPKHGL 301
>gi|224994219 SH3-domain binding protein 2 isoform c [Homo sapiens]
Length = 589
Score = 35.4 bits (80), Expect = 0.15
Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 10/78 (12%)
Query: 472 QHWNHLDEEQA--SPDLWSAPSPEPGGSASLLLAPH---PPHTCSASSLVFSCISHALQW 526
+ + H DE+ + PD SPEPG L+ P PP + FS + A +
Sbjct: 200 EDYEHDDEDDSYLEPD-----SPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSF 254
Query: 527 ISQGRDPIFQPPSPPKGL 544
S+G P+ PP P GL
Sbjct: 255 TSKGPGPLLPPPPPKHGL 272
>gi|170014705 SH3-domain binding protein 2 isoform a [Homo sapiens]
Length = 561
Score = 35.4 bits (80), Expect = 0.15
Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 10/78 (12%)
Query: 472 QHWNHLDEEQA--SPDLWSAPSPEPGGSASLLLAPH---PPHTCSASSLVFSCISHALQW 526
+ + H DE+ + PD SPEPG L+ P PP + FS + A +
Sbjct: 172 EDYEHDDEDDSYLEPD-----SPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSF 226
Query: 527 ISQGRDPIFQPPSPPKGL 544
S+G P+ PP P GL
Sbjct: 227 TSKGPGPLLPPPPPKHGL 244
>gi|170014703 SH3-domain binding protein 2 isoform a [Homo sapiens]
Length = 561
Score = 35.4 bits (80), Expect = 0.15
Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 10/78 (12%)
Query: 472 QHWNHLDEEQA--SPDLWSAPSPEPGGSASLLLAPH---PPHTCSASSLVFSCISHALQW 526
+ + H DE+ + PD SPEPG L+ P PP + FS + A +
Sbjct: 172 EDYEHDDEDDSYLEPD-----SPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSF 226
Query: 527 ISQGRDPIFQPPSPPKGL 544
S+G P+ PP P GL
Sbjct: 227 TSKGPGPLLPPPPPKHGL 244
>gi|121114296 caudal type homeobox 1 [Homo sapiens]
Length = 265
Score = 35.0 bits (79), Expect = 0.19
Identities = 23/81 (28%), Positives = 31/81 (38%), Gaps = 9/81 (11%)
Query: 474 WNHLDEEQASPDLWSAPSPEPGGSASLLLAPHP-PHTCSASSLVFSCISHALQWISQGRD 532
++H++ A P W AP P P + P P S +SL F
Sbjct: 48 YSHVEPAPAPPTAWGAPFPAPKDDWAAAYGPGPAAPAASPASLAFG--------PPPDFS 99
Query: 533 PIFQPPSPPKGLLTHPVAHSG 553
P+ PP P GLL P+ G
Sbjct: 100 PVPAPPGPGPGLLAQPLGGPG 120
>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 33.5 bits (75), Expect = 0.56
Identities = 33/105 (31%), Positives = 38/105 (36%), Gaps = 3/105 (2%)
Query: 477 LDEEQASPDLWSAPSPEPGGSASLLLAPHPPHTCSASSLVFSCIS--HALQWISQGRDPI 534
+ E L S PS P LL P PP V +S H L S P
Sbjct: 154 ISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPD 213
Query: 535 FQPPSPPKGLLTHPVAHSGASILREAAAIHVLVTGSLHLVGGVLK 579
F PP+PP L P A A+ H + T L GGV K
Sbjct: 214 FIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGT-RLFPPGGVTK 257
>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 33.5 bits (75), Expect = 0.56
Identities = 33/105 (31%), Positives = 38/105 (36%), Gaps = 3/105 (2%)
Query: 477 LDEEQASPDLWSAPSPEPGGSASLLLAPHPPHTCSASSLVFSCIS--HALQWISQGRDPI 534
+ E L S PS P LL P PP V +S H L S P
Sbjct: 154 ISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPD 213
Query: 535 FQPPSPPKGLLTHPVAHSGASILREAAAIHVLVTGSLHLVGGVLK 579
F PP+PP L P A A+ H + T L GGV K
Sbjct: 214 FIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGT-RLFPPGGVTK 257
>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo
sapiens]
Length = 1188
Score = 33.5 bits (75), Expect = 0.56
Identities = 33/105 (31%), Positives = 38/105 (36%), Gaps = 3/105 (2%)
Query: 477 LDEEQASPDLWSAPSPEPGGSASLLLAPHPPHTCSASSLVFSCIS--HALQWISQGRDPI 534
+ E L S PS P LL P PP V +S H L S P
Sbjct: 154 ISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPD 213
Query: 535 FQPPSPPKGLLTHPVAHSGASILREAAAIHVLVTGSLHLVGGVLK 579
F PP+PP L P A A+ H + T L GGV K
Sbjct: 214 FIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGT-RLFPPGGVTK 257
>gi|38201702 telomerase reverse transcriptase isoform 2 [Homo
sapiens]
Length = 1120
Score = 32.3 bits (72), Expect = 1.2
Identities = 13/29 (44%), Positives = 15/29 (51%)
Query: 322 RHGAGEPKASRPGLLWQLPLAPVFQPTSH 350
+H AG P SRP W P PV+ T H
Sbjct: 302 QHHAGPPSTSRPPRPWDTPCPPVYAETKH 330
>gi|109633031 telomerase reverse transcriptase isoform 1 [Homo
sapiens]
Length = 1132
Score = 32.3 bits (72), Expect = 1.2
Identities = 13/29 (44%), Positives = 15/29 (51%)
Query: 322 RHGAGEPKASRPGLLWQLPLAPVFQPTSH 350
+H AG P SRP W P PV+ T H
Sbjct: 302 QHHAGPPSTSRPPRPWDTPCPPVYAETKH 330
>gi|41352697 centromere protein I [Homo sapiens]
Length = 756
Score = 32.0 bits (71), Expect = 1.6
Identities = 28/108 (25%), Positives = 46/108 (42%), Gaps = 21/108 (19%)
Query: 32 LSAWPVPQEPS----------------MEYQDAVRMLNTLQTNAGYLEQ--VKRQRGDPQ 73
LSAW V Q+PS E+ D + LQ GY E+ +K + +
Sbjct: 27 LSAWKVKQDPSNSKNISKHGQNNPVGDYEHADDQAEEDALQMAVGYFEKGPIKASQNKDK 86
Query: 74 T---QLEAMELYLARSGLQVEDLDRLNIIHVTGTKGKGSTCAFTECIL 118
T L+ +E ++GL E++D L I ++G G +C++
Sbjct: 87 TLEKHLKTVENVAWKNGLASEEIDILLNIALSGKFGNAVNTRILKCMI 134
>gi|169207217 PREDICTED: zinc finger homeobox 2 [Homo sapiens]
Length = 2790
Score = 31.6 bits (70), Expect = 2.1
Identities = 28/96 (29%), Positives = 35/96 (36%), Gaps = 19/96 (19%)
Query: 480 EQASPDLWSAPSPEPGG--------------SASLLLAPHPPHTCSASSLVFSCISHALQ 525
+QA P + P PE G S L+L H H L F +S
Sbjct: 1677 KQAVPPPPTPPPPEALGGGDKLACGACGKLFSNMLILKTHEEHV-HRRFLPFEALSRYAA 1735
Query: 526 WISQGRD----PIFQPPSPPKGLLTHPVAHSGASIL 557
+ D P+ +PP PP G L PV H G L
Sbjct: 1736 QFRKSYDSLYPPLAEPPKPPDGSLDSPVPHLGPPFL 1771
>gi|169207592 PREDICTED: zinc finger homeobox 2 [Homo sapiens]
Length = 2706
Score = 31.6 bits (70), Expect = 2.1
Identities = 28/96 (29%), Positives = 35/96 (36%), Gaps = 19/96 (19%)
Query: 480 EQASPDLWSAPSPEPGG--------------SASLLLAPHPPHTCSASSLVFSCISHALQ 525
+QA P + P PE G S L+L H H L F +S
Sbjct: 1593 KQAVPPPPTPPPPEALGGGDKLACGACGKLFSNMLILKTHEEHV-HRRFLPFEALSRYAA 1651
Query: 526 WISQGRD----PIFQPPSPPKGLLTHPVAHSGASIL 557
+ D P+ +PP PP G L PV H G L
Sbjct: 1652 QFRKSYDSLYPPLAEPPKPPDGSLDSPVPHLGPPFL 1687
>gi|169207014 PREDICTED: zinc finger homeobox 2 [Homo sapiens]
Length = 2706
Score = 31.6 bits (70), Expect = 2.1
Identities = 28/96 (29%), Positives = 35/96 (36%), Gaps = 19/96 (19%)
Query: 480 EQASPDLWSAPSPEPGG--------------SASLLLAPHPPHTCSASSLVFSCISHALQ 525
+QA P + P PE G S L+L H H L F +S
Sbjct: 1593 KQAVPPPPTPPPPEALGGGDKLACGACGKLFSNMLILKTHEEHV-HRRFLPFEALSRYAA 1651
Query: 526 WISQGRD----PIFQPPSPPKGLLTHPVAHSGASIL 557
+ D P+ +PP PP G L PV H G L
Sbjct: 1652 QFRKSYDSLYPPLAEPPKPPDGSLDSPVPHLGPPFL 1687
>gi|133892686 hypothetical protein LOC727830 [Homo sapiens]
Length = 1347
Score = 31.6 bits (70), Expect = 2.1
Identities = 50/176 (28%), Positives = 65/176 (36%), Gaps = 23/176 (13%)
Query: 340 PLAPVFQPTSHMRLGLRNTEWPGRTQVLRRGPLTWYLDGAHTASSAQACVRWFRQALQ-- 397
PL QP SH LG + T R P+ AH SS F +Q
Sbjct: 464 PLLFQAQPLSH--LGPECQPFISSTPQFRPTPMAQAEAQAHLQSSFPVLSPAFPSLIQNT 521
Query: 398 GRERPSGGPEVRVLLFNATGDRD----------PAALLKLLQPCQFDYAVFCPNLTEVSS 447
G P+ +V+ L T + AL +Q Q ++V PNL + S
Sbjct: 522 GVACPASQNKVQALSLPETQHPEWPLLRRQLEGRLALPSRVQKSQDVFSVSTPNLPQESL 581
Query: 448 TGNADQQNFTVTLDQVLLRCLEHQ------QHWNHLDEEQASPDLWSAPSPEPGGS 497
T + NF V+ + L R LE QHW +L Q S DL PG S
Sbjct: 582 TSILPE-NFPVSPE--LRRQLEQHIKKWIIQHWGNLGRIQESLDLMQLQDESPGTS 634
>gi|223468617 family with sequence similarity 75, member C1 [Homo
sapiens]
Length = 1188
Score = 31.2 bits (69), Expect = 2.8
Identities = 22/67 (32%), Positives = 24/67 (35%), Gaps = 26/67 (38%)
Query: 486 LWSAPSPEPGGSASLLLAPHPPHTCSASSLVFSCISHALQWISQGRDPIFQPPSPPKGLL 545
L PSPEP L PHPPHT DP+ P PPKG
Sbjct: 204 LLERPSPEPPA-----LFPHPPHT---------------------PDPLACSPPPPKGFT 237
Query: 546 THPVAHS 552
P+ S
Sbjct: 238 PPPLRDS 244
>gi|223633941 hypothetical protein LOC389730 [Homo sapiens]
Length = 1343
Score = 31.2 bits (69), Expect = 2.8
Identities = 21/63 (33%), Positives = 23/63 (36%), Gaps = 26/63 (41%)
Query: 490 PSPEPGGSASLLLAPHPPHTCSASSLVFSCISHALQWISQGRDPIFQPPSPPKGLLTHPV 549
PSPEP L PHPPHT DP+ P PPKG P+
Sbjct: 196 PSPEPPA-----LFPHPPHT---------------------PDPLACSPPPPKGFTAPPL 229
Query: 550 AHS 552
S
Sbjct: 230 RDS 232
Score = 30.4 bits (67), Expect = 4.7
Identities = 28/81 (34%), Positives = 36/81 (44%), Gaps = 9/81 (11%)
Query: 423 ALLKLLQPCQFDYAVFCPNLTEVSSTGNADQQNFTVTLDQVLLRCLEHQ------QHWNH 476
AL +Q Q ++V PNL + S T + NF V+ + L R LE QHW +
Sbjct: 553 ALPSRVQKSQDVFSVSTPNLPQESLTSILPE-NFPVSPE--LRRQLEQHIKKWIIQHWGN 609
Query: 477 LDEEQASPDLWSAPSPEPGGS 497
L Q S DL PG S
Sbjct: 610 LGRIQESLDLMQLRDESPGTS 630
>gi|91206406 hypothetical protein LOC642265 [Homo sapiens]
Length = 1347
Score = 31.2 bits (69), Expect = 2.8
Identities = 21/63 (33%), Positives = 23/63 (36%), Gaps = 26/63 (41%)
Query: 490 PSPEPGGSASLLLAPHPPHTCSASSLVFSCISHALQWISQGRDPIFQPPSPPKGLLTHPV 549
PSPEP L PHPPHT DP+ P PPKG P+
Sbjct: 196 PSPEPPA-----LFPHPPHT---------------------PDPLACSPPPPKGFTAPPL 229
Query: 550 AHS 552
S
Sbjct: 230 RDS 232
Score = 30.4 bits (67), Expect = 4.7
Identities = 28/81 (34%), Positives = 36/81 (44%), Gaps = 9/81 (11%)
Query: 423 ALLKLLQPCQFDYAVFCPNLTEVSSTGNADQQNFTVTLDQVLLRCLEHQ------QHWNH 476
AL +Q Q ++V PNL + S T + NF V+ + L R LE QHW +
Sbjct: 557 ALPSRVQKSQDVFSVSTPNLPQESLTSILPE-NFPVSPE--LRRQLEQHIKKWIIQHWGN 613
Query: 477 LDEEQASPDLWSAPSPEPGGS 497
L Q S DL PG S
Sbjct: 614 LGRIQESLDLMQLRDESPGTS 634
>gi|169174618 PREDICTED: family with sequence similarity 75, member
A4 isoform 2 [Homo sapiens]
Length = 1272
Score = 31.2 bits (69), Expect = 2.8
Identities = 50/176 (28%), Positives = 65/176 (36%), Gaps = 23/176 (13%)
Query: 340 PLAPVFQPTSHMRLGLRNTEWPGRTQVLRRGPLTWYLDGAHTASSAQACVRWFRQALQ-- 397
PL QP SH LG + T R P+ AH SS F +Q
Sbjct: 389 PLLFQAQPLSH--LGPECQPFISSTPQFRPTPMAQAEAQAHLQSSFPVLSPAFPSLIQNT 446
Query: 398 GRERPSGGPEVRVLLFNATGDRD----------PAALLKLLQPCQFDYAVFCPNLTEVSS 447
G P+ +V+ L T + AL +Q Q ++V PNL + S
Sbjct: 447 GVACPASQNKVQALSLPETQHPEWPLLRRQLEGRLALPSRVQKSQDVFSVSTPNLPQESL 506
Query: 448 TGNADQQNFTVTLDQVLLRCLEHQ------QHWNHLDEEQASPDLWSAPSPEPGGS 497
T + NF V+ + L R LE QHW +L Q S DL PG S
Sbjct: 507 TSILPE-NFPVSPE--LRRQLEQHIKKWIIQHWGNLGRIQESLDLMQLRDESPGTS 559
>gi|239743732 PREDICTED: family with sequence similarity 75, member
A4 isoform 1 [Homo sapiens]
Length = 1361
Score = 31.2 bits (69), Expect = 2.8
Identities = 50/176 (28%), Positives = 65/176 (36%), Gaps = 23/176 (13%)
Query: 340 PLAPVFQPTSHMRLGLRNTEWPGRTQVLRRGPLTWYLDGAHTASSAQACVRWFRQALQ-- 397
PL QP SH LG + T R P+ AH SS F +Q
Sbjct: 478 PLLFQAQPLSH--LGPECQPFISSTPQFRPTPMAQAEAQAHLQSSFPVLSPAFPSLIQNT 535
Query: 398 GRERPSGGPEVRVLLFNATGDRD----------PAALLKLLQPCQFDYAVFCPNLTEVSS 447
G P+ +V+ L T + AL +Q Q ++V PNL + S
Sbjct: 536 GVACPASQNKVQALSLPETQHPEWPLLRRQLEGRLALPSRVQKSQDVFSVSTPNLPQESL 595
Query: 448 TGNADQQNFTVTLDQVLLRCLEHQ------QHWNHLDEEQASPDLWSAPSPEPGGS 497
T + NF V+ + L R LE QHW +L Q S DL PG S
Sbjct: 596 TSILPE-NFPVSPE--LRRQLEQHIKKWIIQHWGNLGRIQESLDLMQLRDESPGTS 648
>gi|66529407 tensin [Homo sapiens]
Length = 1735
Score = 31.2 bits (69), Expect = 2.8
Identities = 22/77 (28%), Positives = 35/77 (45%), Gaps = 5/77 (6%)
Query: 1 MSRARSHLRAALFLAAASARGITTQVAARRGLSAWPVPQEPSMEYQDAVRMLNTLQTNAG 60
M R++S A L A RG +++ A +RGL++W Q+ + + R Q
Sbjct: 616 MFRSQSFSEAEPQLPPAPVRGGSSREAVQRGLNSWQQQQQQQQQPRPPPR-----QQERA 670
Query: 61 YLEQVKRQRGDPQTQLE 77
+LE + R PQ E
Sbjct: 671 HLESLVASRPSPQPLAE 687
>gi|153791826 hypothetical protein LOC26165 [Homo sapiens]
Length = 1347
Score = 31.2 bits (69), Expect = 2.8
Identities = 50/176 (28%), Positives = 65/176 (36%), Gaps = 23/176 (13%)
Query: 340 PLAPVFQPTSHMRLGLRNTEWPGRTQVLRRGPLTWYLDGAHTASSAQACVRWFRQALQ-- 397
PL QP SH LG + T R P+ AH SS F +Q
Sbjct: 464 PLLFQAQPLSH--LGPECQPFISSTPQFRPTPMAQAEAQAHLQSSFPVLSPAFPSLIQNT 521
Query: 398 GRERPSGGPEVRVLLFNATGDRD----------PAALLKLLQPCQFDYAVFCPNLTEVSS 447
G P+ +V+ L T + AL +Q Q ++V PNL + S
Sbjct: 522 GVACPASQNKVQALSLPETQHPEWPLLRRQLEGRLALPSRVQKSQDVFSVSTPNLPQESL 581
Query: 448 TGNADQQNFTVTLDQVLLRCLEHQ------QHWNHLDEEQASPDLWSAPSPEPGGS 497
T + NF V+ + L R LE QHW +L Q S DL PG S
Sbjct: 582 TSILPE-NFPVSPE--LRRQLEQHIKKWIIQHWGNLGRIQESLDLMQLRDESPGTS 634
>gi|167234417 hypothetical protein LOC441054 [Homo sapiens]
Length = 309
Score = 31.2 bits (69), Expect = 2.8
Identities = 22/55 (40%), Positives = 26/55 (47%), Gaps = 7/55 (12%)
Query: 488 SAPSPEPGGSASLLLAPHPPHTCSASSLVFSCISHALQWISQGRDPIFQPPSPPK 542
S+P +PGG + P+P H SA V L IS D IF PPS PK
Sbjct: 233 SSPGKKPGGMKAGTFDPYPSH--SADPYVAK-----LANISGKDDKIFHPPSGPK 280
>gi|146231958 hypothetical protein LOC647060 [Homo sapiens]
Length = 1347
Score = 31.2 bits (69), Expect = 2.8
Identities = 21/63 (33%), Positives = 23/63 (36%), Gaps = 26/63 (41%)
Query: 490 PSPEPGGSASLLLAPHPPHTCSASSLVFSCISHALQWISQGRDPIFQPPSPPKGLLTHPV 549
PSPEP L PHPPHT DP+ P PPKG P+
Sbjct: 196 PSPEPPA-----LFPHPPHT---------------------PDPLACSPPPPKGFTAPPL 229
Query: 550 AHS 552
S
Sbjct: 230 RDS 232
Score = 30.4 bits (67), Expect = 4.7
Identities = 28/81 (34%), Positives = 36/81 (44%), Gaps = 9/81 (11%)
Query: 423 ALLKLLQPCQFDYAVFCPNLTEVSSTGNADQQNFTVTLDQVLLRCLEHQ------QHWNH 476
AL +Q Q ++V PNL + S T + NF V+ + L R LE QHW +
Sbjct: 557 ALPSRVQKSQDVFSVSTPNLPQESLTSILPE-NFPVSPE--LRRQLEQHIKKWIIQHWGN 613
Query: 477 LDEEQASPDLWSAPSPEPGGS 497
L Q S DL PG S
Sbjct: 614 LGRIQESLDLMQLRDESPGTS 634
>gi|165377334 hypothetical protein LOC727905 [Homo sapiens]
Length = 1347
Score = 31.2 bits (69), Expect = 2.8
Identities = 50/176 (28%), Positives = 65/176 (36%), Gaps = 23/176 (13%)
Query: 340 PLAPVFQPTSHMRLGLRNTEWPGRTQVLRRGPLTWYLDGAHTASSAQACVRWFRQALQ-- 397
PL QP SH LG + T R P+ AH SS F +Q
Sbjct: 464 PLLFQAQPLSH--LGPECQPFISSTPQFRPTPMAQAEAQAHLQSSFPVLSPAFPSLIQNT 521
Query: 398 GRERPSGGPEVRVLLFNATGDRD----------PAALLKLLQPCQFDYAVFCPNLTEVSS 447
G P+ +V+ L T + AL +Q Q ++V PNL + S
Sbjct: 522 GVACPASQNKVQALSLPETQHPEWPLLRRQLEGRLALPSRVQKSQDVFSVSTPNLPQESL 581
Query: 448 TGNADQQNFTVTLDQVLLRCLEHQ------QHWNHLDEEQASPDLWSAPSPEPGGS 497
T + NF V+ + L R LE QHW +L Q S DL PG S
Sbjct: 582 TSILPE-NFPVSPE--LRRQLEQHIKKWIIQHWGNLGRIQESLDLMQLRDESPGTS 634
>gi|238859651 pleckstrin homology domain containing family A member
4 isoform 1 [Homo sapiens]
Length = 779
Score = 30.4 bits (67), Expect = 4.7
Identities = 16/39 (41%), Positives = 19/39 (48%), Gaps = 3/39 (7%)
Query: 472 QHWNHLDEEQA---SPDLWSAPSPEPGGSASLLLAPHPP 507
QHW+ QA SP P PG AS++L P PP
Sbjct: 315 QHWSQEPRTQAHSGSPTYLQLPPRPPGTRASMVLLPGPP 353
>gi|126507091 LATS, large tumor suppressor, homolog 2 [Homo sapiens]
Length = 1088
Score = 30.4 bits (67), Expect = 4.7
Identities = 26/87 (29%), Positives = 32/87 (36%), Gaps = 28/87 (32%)
Query: 481 QASPDLWSAPSPEPGGSASL---------------------LLAPHPPHTCSASSLVFSC 519
Q SP S PE GG ASL L PHP H + +
Sbjct: 270 QRSPSFQSKTPPETGGYASLPTKGQGGPPGAGLAFPPPAAGLYVPHPHHKQAGPA----- 324
Query: 520 ISHALQWISQGRDPIFQPPSPPKGLLT 546
+H L + R +F SPP+ LLT
Sbjct: 325 -AHQLH-VLGSRSQVFASDSPPQSLLT 349
>gi|4885187 distal-less homeobox 5 [Homo sapiens]
Length = 289
Score = 30.0 bits (66), Expect = 6.2
Identities = 23/75 (30%), Positives = 33/75 (44%), Gaps = 7/75 (9%)
Query: 483 SPDLWSAPSPEPGGSA-SLLLAPHPPHTCSASSLVFSCISHALQWISQGRDPIFQPPSPP 541
SP +W EP GS+ SL PH S S S + ++ W + I PP
Sbjct: 220 SPAVW-----EPQGSSRSLSHHPHAHPPTSNQSPASSYLENSASWYTSAASSI-NSHLPP 273
Query: 542 KGLLTHPVAHSGASI 556
G L HP+A + ++
Sbjct: 274 PGSLQHPLALASGTL 288
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.136 0.424
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,601,324
Number of Sequences: 37866
Number of extensions: 1305582
Number of successful extensions: 3728
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 28
Number of HSP's that attempted gapping in prelim test: 3678
Number of HSP's gapped (non-prelim): 64
length of query: 587
length of database: 18,247,518
effective HSP length: 108
effective length of query: 479
effective length of database: 14,157,990
effective search space: 6781677210
effective search space used: 6781677210
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.