Guide to the Human Genome
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Name: FPGS Sequence: fasta or formatted (587aa) NCBI GI: 66932984
Description:

folylpolyglutamate synthase isoform a precursor

Referenced in:

Vitamin Pathways, Coenzymes, and 1-Carbon Metabolism

Other entries for this name:
alt prot [537aa] folylpolyglutamate synthase isoform b
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.9         52           3
 C cysteine            2.4         14           1
 D aspartate           3.4         20           1
 E glutamate           5.3         31           2
 F phenylalanine       3.4         20           2
 G glycine             7.8         46           2
 H histidine           3.6         21           1
 I isoleucine          3.2         19           2
 K lysine              2.6         15           1
 L leucine            13.3         78           3
 M methionine          1.4          8           1
 N asparagine          2.0         12           1
 P proline             7.3         43           2
 Q glutamine           6.6         39           2
 R arginine            6.6         39           2
 S serine              7.0         41           2
 T threonine           5.3         31           2
 V valine              6.1         36           2
 W tryptophan          1.9         11           1
 Y tyrosine            1.9         11           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   folylpolyglutamate synthase isoform a precursor [Hom... 
FPGS                  0.919   folylpolyglutamate synthase isoform b 
SH3BP2                0.009   SH3-domain binding protein 2 isoform b 
SH3BP2                0.009   SH3-domain binding protein 2 isoform c 
SH3BP2                0.009   SH3-domain binding protein 2 isoform a 
SH3BP2                0.009   SH3-domain binding protein 2 isoform a 
CDX1                  0.009   caudal type homeobox 1 
C6orf132              0.007   PREDICTED: chromosome 6 open reading frame 132 [Hom...
C6orf132              0.007   PREDICTED: chromosome 6 open reading frame 132 [Hom...
C6orf132              0.007   PREDICTED: hypothetical protein LOC647024 
TERT                  0.006   telomerase reverse transcriptase isoform 2 
TERT                  0.006   telomerase reverse transcriptase isoform 1 
CENPI                 0.006   centromere protein I 
ZFHX2                 0.006   PREDICTED: zinc finger homeobox 2 
ZFHX2                 0.006   PREDICTED: zinc finger homeobox 2 
ZFHX2                 0.006   PREDICTED: zinc finger homeobox 2 
FAM75A3               0.006   hypothetical protein LOC727830 
FAM75C1               0.005   family with sequence similarity 75, member C1 [Homo...
FAM75A6               0.005   hypothetical protein LOC389730 
FAM75A2               0.005   hypothetical protein LOC642265 
FAM75A4               0.005   PREDICTED: family with sequence similarity 75, memb...
FAM75A4               0.005   PREDICTED: family with sequence similarity 75, memb...
TNS1                  0.005   tensin 
FAM75A7               0.005   hypothetical protein LOC26165 
C4orf47               0.005   hypothetical protein LOC441054 
FAM75A1               0.005   hypothetical protein LOC647060 
FAM75A5               0.005   hypothetical protein LOC727905 
PLEKHA4               0.004   pleckstrin homology domain containing family A memb...
LATS2                 0.004   LATS, large tumor suppressor, homolog 2 
DLX5                  0.004   distal-less homeobox 5 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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