Guide to the Human Genome
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Search of human proteins with 66932943

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|66932943 variable charge, X chromosome [Homo sapiens]
         (206 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|66932943 variable charge, X chromosome [Homo sapiens]              401   e-112
gi|149999615 variable charge, X-linked 3B [Homo sapiens]              385   e-107
gi|48762947 variable charge, X-linked 3A [Homo sapiens]               353   7e-98
gi|49619239 variable charge, X-linked 2 [Homo sapiens]                248   2e-66
gi|49355828 variable charge, Y-linked 1B [Homo sapiens]               217   6e-57
gi|4759304 variable charge, Y-linked [Homo sapiens]                   217   6e-57
gi|44890059 involucrin [Homo sapiens]                                  80   1e-15
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     60   2e-09
gi|16445033 ACRC protein [Homo sapiens]                                58   5e-09
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    58   6e-09
gi|4506879 selectin P ligand [Homo sapiens]                            57   1e-08
gi|110349719 titin isoform N2-A [Homo sapiens]                         54   7e-08
gi|239745855 PREDICTED: hypothetical protein XP_002343606 [Homo ...    54   7e-08
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]              54   7e-08
gi|149773456 hypothetical protein LOC643314 [Homo sapiens]             54   9e-08
gi|21361639 DIPB protein [Homo sapiens]                                54   1e-07
gi|217330641 IWS1 homolog [Homo sapiens]                               53   2e-07
gi|150170670 piccolo isoform 2 [Homo sapiens]                          53   2e-07
gi|150378539 piccolo isoform 1 [Homo sapiens]                          53   2e-07
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ...    52   3e-07
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ...    52   3e-07
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)...    52   5e-07
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)...    52   5e-07
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)...    52   5e-07
gi|75677612 leucine rich repeat containing 37, member A3 [Homo s...    51   6e-07
gi|239740955 PREDICTED: similar to c114 SLIT-like testicular pro...    51   8e-07
gi|239740953 PREDICTED: similar to c114 SLIT-like testicular pro...    51   8e-07
gi|116325993 c114 SLIT-like testicular protein [Homo sapiens]          51   8e-07
gi|110665701 leucine rich repeat containing 37A [Homo sapiens]         51   8e-07
gi|78042577 MAP7 domain containing 1 [Homo sapiens]                    50   1e-06

>gi|66932943 variable charge, X chromosome [Homo sapiens]
          Length = 206

 Score =  401 bits (1031), Expect = e-112
 Identities = 206/206 (100%), Positives = 206/206 (100%)

Query: 1   MSPKPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMA 60
           MSPKPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMA
Sbjct: 1   MSPKPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMA 60

Query: 61  AVTAPEAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEV 120
           AVTAPEAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEV
Sbjct: 61  AVTAPEAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEV 120

Query: 121 EEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEM 180
           EEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEM
Sbjct: 121 EEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEM 180

Query: 181 EEPLSQESQVEEPPSQESEMEELPSV 206
           EEPLSQESQVEEPPSQESEMEELPSV
Sbjct: 181 EEPLSQESQVEEPPSQESEMEELPSV 206


>gi|149999615 variable charge, X-linked 3B [Homo sapiens]
          Length = 216

 Score =  385 bits (989), Expect = e-107
 Identities = 198/202 (98%), Positives = 199/202 (98%)

Query: 1   MSPKPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMA 60
           MSPKPRASGPPAKA EAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMA
Sbjct: 1   MSPKPRASGPPAKAKEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMA 60

Query: 61  AVTAPEAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEV 120
           AVTAPEAES PAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQE+ELEEPLSQESEV
Sbjct: 61  AVTAPEAESGPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQESELEEPLSQESEV 120

Query: 121 EEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEM 180
           EEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEM
Sbjct: 121 EEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEM 180

Query: 181 EEPLSQESQVEEPPSQESEMEE 202
           EEPLSQESQVEEP SQESEMEE
Sbjct: 181 EEPLSQESQVEEPLSQESEMEE 202


>gi|48762947 variable charge, X-linked 3A [Homo sapiens]
          Length = 186

 Score =  353 bits (905), Expect = 7e-98
 Identities = 180/182 (98%), Positives = 181/182 (99%)

Query: 1   MSPKPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMA 60
           MSPKPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMA
Sbjct: 1   MSPKPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMA 60

Query: 61  AVTAPEAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEV 120
           AVTAPEAES PAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQE+ELEEPLSQESEV
Sbjct: 61  AVTAPEAESGPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQESELEEPLSQESEV 120

Query: 121 EEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEM 180
           EEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEM
Sbjct: 121 EEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEM 180

Query: 181 EE 182
           EE
Sbjct: 181 EE 182


>gi|49619239 variable charge, X-linked 2 [Homo sapiens]
          Length = 139

 Score =  248 bits (634), Expect = 2e-66
 Identities = 124/139 (89%), Positives = 131/139 (94%)

Query: 1   MSPKPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMA 60
           MSPKPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMA
Sbjct: 1   MSPKPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMA 60

Query: 61  AVTAPEAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEV 120
           AVTAPEAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQE+E+EEPLSQESEV
Sbjct: 61  AVTAPEAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQESEVEEPLSQESEV 120

Query: 121 EEPLSQESQVEEPLSQESE 139
           EEPL+       P+S+ ++
Sbjct: 121 EEPLTVWMASFSPVSESTD 139



 Score = 45.1 bits (105), Expect = 4e-05
 Identities = 27/56 (48%), Positives = 33/56 (58%), Gaps = 1/56 (1%)

Query: 147 ESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPLSQESQVEEPPSQESEMEE 202
           ES    P   +   +E    E   EEP+S E    +PLSQES+VEEP SQESE+EE
Sbjct: 68  ESAPAAPGPSDQPSQELPQHELPPEEPVS-EGTQHDPLSQESEVEEPLSQESEVEE 122


>gi|49355828 variable charge, Y-linked 1B [Homo sapiens]
          Length = 125

 Score =  217 bits (552), Expect = 6e-57
 Identities = 107/116 (92%), Positives = 111/116 (95%)

Query: 1   MSPKPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMA 60
           MSPKPRASGPPAKA E GKRKSSSQPSPS PKKKTTKVA+KG+AVR GRRGKKGAATKMA
Sbjct: 1   MSPKPRASGPPAKAKETGKRKSSSQPSPSGPKKKTTKVAEKGEAVRGGRRGKKGAATKMA 60

Query: 61  AVTAPEAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQ 116
           AVTAPEAES PAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQE+ELEEPLS+
Sbjct: 61  AVTAPEAESGPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQESELEEPLSK 116



 Score = 37.4 bits (85), Expect = 0.009
 Identities = 22/50 (44%), Positives = 30/50 (60%), Gaps = 1/50 (2%)

Query: 137 ESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPLSQ 186
           ES    P   +   +E    E   EEP+S+ +Q  +PLSQESE+EEPLS+
Sbjct: 68  ESGPAAPGPSDQPSQELPQHELPPEEPVSEGTQ-HDPLSQESELEEPLSK 116



 Score = 32.3 bits (72), Expect = 0.29
 Identities = 20/50 (40%), Positives = 27/50 (54%), Gaps = 1/50 (2%)

Query: 147 ESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPLSQESQVEEPPSQ 196
           ES    P   +   +E    E   EEP+S E    +PLSQES++EEP S+
Sbjct: 68  ESGPAAPGPSDQPSQELPQHELPPEEPVS-EGTQHDPLSQESELEEPLSK 116



 Score = 28.5 bits (62), Expect = 4.2
 Identities = 18/46 (39%), Positives = 25/46 (54%), Gaps = 1/46 (2%)

Query: 157 ESEVEEPLSQESQVEEPLSQESEMEEPLSQESQVEEPPSQESEMEE 202
           ES    P   +   +E    E   EEP+S+ +Q  +P SQESE+EE
Sbjct: 68  ESGPAAPGPSDQPSQELPQHELPPEEPVSEGTQ-HDPLSQESELEE 112


>gi|4759304 variable charge, Y-linked [Homo sapiens]
          Length = 125

 Score =  217 bits (552), Expect = 6e-57
 Identities = 107/116 (92%), Positives = 111/116 (95%)

Query: 1   MSPKPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMA 60
           MSPKPRASGPPAKA E GKRKSSSQPSPS PKKKTTKVA+KG+AVR GRRGKKGAATKMA
Sbjct: 1   MSPKPRASGPPAKAKETGKRKSSSQPSPSGPKKKTTKVAEKGEAVRGGRRGKKGAATKMA 60

Query: 61  AVTAPEAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQ 116
           AVTAPEAES PAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQE+ELEEPLS+
Sbjct: 61  AVTAPEAESGPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQESELEEPLSK 116



 Score = 37.4 bits (85), Expect = 0.009
 Identities = 22/50 (44%), Positives = 30/50 (60%), Gaps = 1/50 (2%)

Query: 137 ESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPLSQ 186
           ES    P   +   +E    E   EEP+S+ +Q  +PLSQESE+EEPLS+
Sbjct: 68  ESGPAAPGPSDQPSQELPQHELPPEEPVSEGTQ-HDPLSQESELEEPLSK 116



 Score = 32.3 bits (72), Expect = 0.29
 Identities = 20/50 (40%), Positives = 27/50 (54%), Gaps = 1/50 (2%)

Query: 147 ESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPLSQESQVEEPPSQ 196
           ES    P   +   +E    E   EEP+S E    +PLSQES++EEP S+
Sbjct: 68  ESGPAAPGPSDQPSQELPQHELPPEEPVS-EGTQHDPLSQESELEEPLSK 116



 Score = 28.5 bits (62), Expect = 4.2
 Identities = 18/46 (39%), Positives = 25/46 (54%), Gaps = 1/46 (2%)

Query: 157 ESEVEEPLSQESQVEEPLSQESEMEEPLSQESQVEEPPSQESEMEE 202
           ES    P   +   +E    E   EEP+S+ +Q  +P SQESE+EE
Sbjct: 68  ESGPAAPGPSDQPSQELPQHELPPEEPVSEGTQ-HDPLSQESELEE 112


>gi|44890059 involucrin [Homo sapiens]
          Length = 585

 Score = 80.1 bits (196), Expect = 1e-15
 Identities = 46/116 (39%), Positives = 65/116 (56%), Gaps = 3/116 (2%)

Query: 88  ELPPEEPVSEGTQHDPLSQEAELEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQE 147
           ELP ++   EG       QE +L+ P  QE ++E P  QE Q+E P  QE ++E P  QE
Sbjct: 154 ELPEQQ---EGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQE 210

Query: 148 SQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPLSQESQVEEPPSQESEMEEL 203
            Q+E P  QE ++E P  QE Q+E P  QE ++E    QE Q+E    QE +++ L
Sbjct: 211 GQLELPEQQEGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHL 266



 Score = 78.2 bits (191), Expect = 5e-15
 Identities = 43/105 (40%), Positives = 59/105 (56%)

Query: 97  EGTQHDPLSQEAELEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQ 156
           EG    P  QE +LE P  QE ++E P  QE Q+E P  QE ++E P  QE Q+E P  Q
Sbjct: 170 EGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQ 229

Query: 157 ESEVEEPLSQESQVEEPLSQESEMEEPLSQESQVEEPPSQESEME 201
           E ++E P  QE Q+E    QE ++E    QE Q++    QE ++E
Sbjct: 230 EGQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLE 274



 Score = 77.0 bits (188), Expect = 1e-14
 Identities = 47/129 (36%), Positives = 68/129 (52%), Gaps = 3/129 (2%)

Query: 75  GPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEVEEPLSQESQVEEPL 134
           G    P Q+  Q ELP ++   EG    P  QE +LE P  QE ++E P  QE Q+E P 
Sbjct: 171 GQLKHPEQQEGQLELPEQQ---EGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPE 227

Query: 135 SQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPLSQESQVEEPP 194
            QE ++E P  QE Q+E    QE ++E    QE Q++    QE ++E P  Q  Q++   
Sbjct: 228 QQEGQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLE 287

Query: 195 SQESEMEEL 203
            QE +++ L
Sbjct: 288 QQEGQLKHL 296



 Score = 76.3 bits (186), Expect = 2e-14
 Identities = 40/98 (40%), Positives = 57/98 (58%)

Query: 104 LSQEAELEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEP 163
           + +E  LE P  QE  ++    QE Q++ P  QE ++E P  QE Q+E P  QE ++E P
Sbjct: 147 MKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLELP 206

Query: 164 LSQESQVEEPLSQESEMEEPLSQESQVEEPPSQESEME 201
             QE Q+E P  QE ++E P  QE Q+E P  QE ++E
Sbjct: 207 EQQEGQLELPEQQEGQLELPEQQEGQLELPQQQEGQLE 244



 Score = 71.6 bits (174), Expect = 4e-13
 Identities = 45/127 (35%), Positives = 66/127 (51%), Gaps = 3/127 (2%)

Query: 75  GPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEVEEPLSQESQVEEPL 134
           G  + P Q+  Q ELP ++   EG    P  QE +LE P  QE ++E P  QE Q+E P 
Sbjct: 181 GQLELPEQQEGQLELPEQQ---EGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPQ 237

Query: 135 SQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPLSQESQVEEPP 194
            QE ++E    QE Q+E    QE +++    QE Q+E P  Q  +++    QE Q++   
Sbjct: 238 QQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLD 297

Query: 195 SQESEME 201
            QE + E
Sbjct: 298 QQEKQPE 304



 Score = 68.9 bits (167), Expect = 3e-12
 Identities = 44/129 (34%), Positives = 66/129 (51%), Gaps = 3/129 (2%)

Query: 75  GPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEVEEPLSQESQVEEPL 134
           G  + P Q+  Q ELP ++   EG    P  QE +LE P  QE ++E P  QE Q+E   
Sbjct: 191 GQLELPEQQEGQLELPEQQ---EGQLELPEQQEGQLELPEQQEGQLELPQQQEGQLELSE 247

Query: 135 SQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPLSQESQVEEPP 194
            QE ++E    QE Q++    QE ++E P  Q  Q++    QE +++    QE Q E P 
Sbjct: 248 QQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQEKQPELPE 307

Query: 195 SQESEMEEL 203
            Q  +++ L
Sbjct: 308 QQMGQLKHL 316



 Score = 62.8 bits (151), Expect = 2e-10
 Identities = 42/129 (32%), Positives = 64/129 (49%), Gaps = 3/129 (2%)

Query: 75  GPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEVEEPLSQESQVEEPL 134
           G  + P Q+  Q ELP ++   EG    P  QE +LE P  QE ++E    QE Q+E   
Sbjct: 201 GQLELPEQQEGQLELPEQQ---EGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSE 257

Query: 135 SQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPLSQESQVEEPP 194
            QE +++    QE Q+E P  Q  +++    QE Q++    QE + E P  Q  Q++   
Sbjct: 258 QQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQEKQPELPEQQMGQLKHLE 317

Query: 195 SQESEMEEL 203
            QE + + L
Sbjct: 318 QQEGQPKHL 326



 Score = 61.6 bits (148), Expect = 4e-10
 Identities = 41/129 (31%), Positives = 64/129 (49%), Gaps = 3/129 (2%)

Query: 75  GPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEVEEPLSQESQVEEPL 134
           G  + P Q+  Q ELP ++   EG    P  QE +LE    QE ++E    QE Q++   
Sbjct: 211 GQLELPEQQEGQLELPEQQ---EGQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLE 267

Query: 135 SQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPLSQESQVEEPP 194
            QE ++E P  Q  Q++    QE +++    QE Q E P  Q  +++    QE Q +   
Sbjct: 268 HQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLE 327

Query: 195 SQESEMEEL 203
            QE ++E+L
Sbjct: 328 QQEGQLEQL 336



 Score = 56.6 bits (135), Expect = 1e-08
 Identities = 39/129 (30%), Positives = 63/129 (48%), Gaps = 3/129 (2%)

Query: 75  GPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEVEEPLSQESQVEEPL 134
           G  + P Q+  Q ELP ++   EG       QE +LE    QE +++    QE Q+E P 
Sbjct: 221 GQLELPEQQEGQLELPQQQ---EGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPE 277

Query: 135 SQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPLSQESQVEEPP 194
            Q  +++    QE Q++    QE + E P  Q  Q++    QE + +    QE Q+E+  
Sbjct: 278 EQMGQLKYLEQQEGQLKHLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLE 337

Query: 195 SQESEMEEL 203
            QE +++ L
Sbjct: 338 EQEGQLKHL 346



 Score = 55.5 bits (132), Expect = 3e-08
 Identities = 30/98 (30%), Positives = 52/98 (53%)

Query: 106 QEAELEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLS 165
           QE +L+    Q+ ++E P  Q  Q +    +E ++E P  QE QV+    QE+++E P  
Sbjct: 436 QEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQQEGQVKHLEKQEAQLELPEQ 495

Query: 166 QESQVEEPLSQESEMEEPLSQESQVEEPPSQESEMEEL 203
           Q  Q +    QE  +E P  Q+ Q++    QE ++++L
Sbjct: 496 QVGQPKHLEQQEKHLEHPEQQDGQLKHLEQQEGQLKDL 533



 Score = 53.5 bits (127), Expect = 1e-07
 Identities = 28/97 (28%), Positives = 52/97 (53%)

Query: 106 QEAELEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLS 165
           Q+ +LE P  Q  + +    +E Q+E P  QE +V+    QE+Q+E P  Q  + +    
Sbjct: 446 QQGQLEVPEQQVGQPKNLEQEEKQLELPEQQEGQVKHLEKQEAQLELPEQQVGQPKHLEQ 505

Query: 166 QESQVEEPLSQESEMEEPLSQESQVEEPPSQESEMEE 202
           QE  +E P  Q+ +++    QE Q+++   Q+ ++E+
Sbjct: 506 QEKHLEHPEQQDGQLKHLEQQEGQLKDLEQQKGQLEQ 542



 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 33/128 (25%), Positives = 62/128 (48%), Gaps = 7/128 (5%)

Query: 82  QELPQHELPPEE-------PVSEGTQHDPLSQEAELEEPLSQESEVEEPLSQESQVEEPL 134
           Q+  Q ELP ++          EG       QE +LE+   QE +++    QE Q+E   
Sbjct: 298 QQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLE 357

Query: 135 SQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPLSQESQVEEPP 194
            QE ++  P  Q  Q+++   Q+ + +    +E Q++  + QE +++  + QE Q+E+  
Sbjct: 358 HQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQE 417

Query: 195 SQESEMEE 202
            Q   +E+
Sbjct: 418 RQVEHLEQ 425



 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 28/98 (28%), Positives = 50/98 (51%)

Query: 106 QEAELEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLS 165
           Q  +L+    QE +++    Q+ Q+E P  Q  + +    +E Q+E P  QE +V+    
Sbjct: 426 QVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQQEGQVKHLEK 485

Query: 166 QESQVEEPLSQESEMEEPLSQESQVEEPPSQESEMEEL 203
           QE+Q+E P  Q  + +    QE  +E P  Q+ +++ L
Sbjct: 486 QEAQLELPEQQVGQPKHLEQQEKHLEHPEQQDGQLKHL 523



 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 28/97 (28%), Positives = 50/97 (51%)

Query: 97  EGTQHDPLSQEAELEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQ 156
           +G    P  Q  + +    +E ++E P  QE QV+    QE+++E P  Q  Q +    Q
Sbjct: 447 QGQLEVPEQQVGQPKNLEQEEKQLELPEQQEGQVKHLEKQEAQLELPEQQVGQPKHLEQQ 506

Query: 157 ESEVEEPLSQESQVEEPLSQESEMEEPLSQESQVEEP 193
           E  +E P  Q+ Q++    QE ++++   Q+ Q+E+P
Sbjct: 507 EKHLEHPEQQDGQLKHLEQQEGQLKDLEQQKGQLEQP 543



 Score = 50.1 bits (118), Expect = 1e-06
 Identities = 30/103 (29%), Positives = 55/103 (53%), Gaps = 7/103 (6%)

Query: 106 QEAELEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLS 165
           +E +L+  + QE +++  + QE Q+E+   Q   +E+ + Q   +EE   Q   +E+   
Sbjct: 389 EEGQLKHLVQQEGQLKHLVQQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQG 448

Query: 166 Q----ESQVEEPLS---QESEMEEPLSQESQVEEPPSQESEME 201
           Q    E QV +P +   +E ++E P  QE QV+    QE+++E
Sbjct: 449 QLEVPEQQVGQPKNLEQEEKQLELPEQQEGQVKHLEKQEAQLE 491



 Score = 50.1 bits (118), Expect = 1e-06
 Identities = 31/107 (28%), Positives = 54/107 (50%), Gaps = 3/107 (2%)

Query: 97  EGTQHDPLSQEAELEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQ 156
           EG     + QE +LE+   Q   +E+ + Q   +EE   QE +++    Q+ Q+E P  Q
Sbjct: 400 EGQLKHLVQQEGQLEQQERQVEHLEQQVGQLKHLEE---QEGQLKHLEQQQGQLEVPEQQ 456

Query: 157 ESEVEEPLSQESQVEEPLSQESEMEEPLSQESQVEEPPSQESEMEEL 203
             + +    +E Q+E P  QE +++    QE+Q+E P  Q  + + L
Sbjct: 457 VGQPKNLEQEEKQLELPEQQEGQVKHLEKQEAQLELPEQQVGQPKHL 503



 Score = 49.3 bits (116), Expect = 2e-06
 Identities = 37/133 (27%), Positives = 60/133 (45%), Gaps = 7/133 (5%)

Query: 75  GPSDQPSQELPQHELPPEEP-------VSEGTQHDPLSQEAELEEPLSQESEVEEPLSQE 127
           G  + P Q+  Q EL  ++          EG       QE +LE P  Q  +++    QE
Sbjct: 231 GQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQE 290

Query: 128 SQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPLSQE 187
            Q++    QE + E P  Q  Q++    QE + +    QE Q+E+   QE +++    QE
Sbjct: 291 GQLKHLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQE 350

Query: 188 SQVEEPPSQESEM 200
            Q+E    QE ++
Sbjct: 351 GQLEHLEHQEGQL 363



 Score = 49.3 bits (116), Expect = 2e-06
 Identities = 29/103 (28%), Positives = 55/103 (53%), Gaps = 3/103 (2%)

Query: 82  QELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEVEEPLSQESQVEEPLSQESEVE 141
           Q+  Q E+P ++    G   +   +E +LE P  QE +V+    QE+Q+E P  Q  + +
Sbjct: 445 QQQGQLEVPEQQV---GQPKNLEQEEKQLELPEQQEGQVKHLEKQEAQLELPEQQVGQPK 501

Query: 142 EPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPL 184
               QE  +E P  Q+ +++    QE Q+++   Q+ ++E+P+
Sbjct: 502 HLEQQEKHLEHPEQQDGQLKHLEQQEGQLKDLEQQKGQLEQPV 544



 Score = 48.9 bits (115), Expect = 3e-06
 Identities = 32/105 (30%), Positives = 50/105 (47%), Gaps = 3/105 (2%)

Query: 97  EGTQHDPLSQEAELEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQ 156
           EG       Q   LE+ + Q   +EE   QE Q++    Q+ ++E P  Q  Q +    +
Sbjct: 410 EGQLEQQERQVEHLEQQVGQLKHLEE---QEGQLKHLEQQQGQLEVPEQQVGQPKNLEQE 466

Query: 157 ESEVEEPLSQESQVEEPLSQESEMEEPLSQESQVEEPPSQESEME 201
           E ++E P  QE QV+    QE+++E P  Q  Q +    QE  +E
Sbjct: 467 EKQLELPEQQEGQVKHLEKQEAQLELPEQQVGQPKHLEQQEKHLE 511



 Score = 46.6 bits (109), Expect = 1e-05
 Identities = 34/148 (22%), Positives = 64/148 (43%), Gaps = 11/148 (7%)

Query: 66  EAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLS-----------QEAELEEPL 114
           + E  P  P       + L Q E  P+    +  Q + L            QE +LE   
Sbjct: 298 QQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLE 357

Query: 115 SQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPL 174
            QE ++  P  Q  Q+++   Q+ + +    +E Q++  + QE +++  + QE Q+E+  
Sbjct: 358 HQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQE 417

Query: 175 SQESEMEEPLSQESQVEEPPSQESEMEE 202
            Q   +E+ + Q   +EE   Q   +E+
Sbjct: 418 RQVEHLEQQVGQLKHLEEQEGQLKHLEQ 445



 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 30/100 (30%), Positives = 50/100 (50%), Gaps = 3/100 (3%)

Query: 106 QEAELEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLS 165
           QE +L+    QE + E P  Q  Q++    QE + +    QE Q+E+   QE +++    
Sbjct: 289 QEGQLKHLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQ 348

Query: 166 QESQVEEPLSQESEM---EEPLSQESQVEEPPSQESEMEE 202
           QE Q+E    QE ++   E+ + Q  Q+E+   Q   +EE
Sbjct: 349 QEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEE 388



 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 30/110 (27%), Positives = 54/110 (49%), Gaps = 7/110 (6%)

Query: 98  GTQHDPLSQEAELEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQE 157
           G     + Q  +LE+   Q   +EE   +E Q++  + QE +++  + QE Q+E+   Q 
Sbjct: 364 GLPEQQVLQLKQLEKQQGQPKHLEE---EEGQLKHLVQQEGQLKHLVQQEGQLEQQERQV 420

Query: 158 SEVEEPLSQESQVEEPLSQESEMEEPLSQ----ESQVEEPPSQESEMEEL 203
             +E+ + Q   +EE   Q   +E+   Q    E QV +P + E E ++L
Sbjct: 421 EHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQL 470



 Score = 44.3 bits (103), Expect = 7e-05
 Identities = 36/131 (27%), Positives = 61/131 (46%), Gaps = 19/131 (14%)

Query: 82  QELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEVEEPLSQESQVEEPLSQESEVE 141
           + L Q E  PE P  +      + Q   LE+   Q   +E+   QE Q+E+   QE +++
Sbjct: 294 KHLDQQEKQPELPEQQ------MGQLKHLEQQEGQPKHLEQ---QEGQLEQLEEQEGQLK 344

Query: 142 EPLSQESQVEEPLSQESEV---EEPLSQESQVEEPLSQESEMEEP-------LSQESQVE 191
               QE Q+E    QE ++   E+ + Q  Q+E+   Q   +EE        + QE Q++
Sbjct: 345 HLEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLK 404

Query: 192 EPPSQESEMEE 202
               QE ++E+
Sbjct: 405 HLVQQEGQLEQ 415


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 59.7 bits (143), Expect = 2e-09
 Identities = 53/217 (24%), Positives = 101/217 (46%), Gaps = 20/217 (9%)

Query: 2   SPKPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKA-----VRRGRRGKKGAA 56
           SP    +  P KA    K ++ S      P K+  K  +K K+      +   + K    
Sbjct: 696 SPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEK 755

Query: 57  TKMAAVTAPEAESAPAAPGPSDQPSQELPQHELPP--EEPVSEGTQHDPLSQEAEL-EEP 113
            K   V +PEA++   A   +  P+ + P+    P  EE  S      PL ++A+  E+ 
Sbjct: 756 AKTLDVKSPEAKTP--AKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKE 813

Query: 114 LSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQES--QVE 171
           + ++ EV+ P+ +E   E+P  QE +V+EP  +  + + P + ++E ++   +E   + E
Sbjct: 814 IPKKEEVKSPVKEE---EKP--QEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKE 868

Query: 172 EPLSQESEMEEPL---SQESQVEEPPSQESEMEELPS 205
            P  +  E +EP     +ES+VE    +  + +++P+
Sbjct: 869 APKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPT 905



 Score = 56.6 bits (135), Expect = 1e-08
 Identities = 43/206 (20%), Positives = 87/206 (42%), Gaps = 8/206 (3%)

Query: 2   SPKPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMAA 61
           SP    +  PA+A    K ++ S      P+K  +   ++ K+    +  +K  A   A 
Sbjct: 518 SPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAE 577

Query: 62  VTAPEAESAPA---APGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQES 118
           V +PE   +PA   A  P++  S E  +  +  EE  S      P+ +EA+    +    
Sbjct: 578 VKSPEKAKSPAKEEAKSPAEAKSPEKAKSPV-KEEAKSPAEAKSPVKEEAKSPAEVKSPE 636

Query: 119 EVEEPLSQESQVEEPLS--QESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQ 176
           + + P  +E++  E     ++ E + P   +S V+       + + P+  E+  + P   
Sbjct: 637 KAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEA--KSPEKA 694

Query: 177 ESEMEEPLSQESQVEEPPSQESEMEE 202
           +S ++E      + + P  +E++  E
Sbjct: 695 KSPVKEEAKSPEKAKSPVKEEAKSPE 720



 Score = 55.5 bits (132), Expect = 3e-08
 Identities = 43/197 (21%), Positives = 84/197 (42%), Gaps = 9/197 (4%)

Query: 9   GPPAKATEAGKRKSSSQPSP---SDPKKKTTKVAKKGKAVRRGRRGKKGAATKMAAVTAP 65
           G   +  E G+ ++ S P+    S  K+  + V ++ K+    +  +K  A   A V +P
Sbjct: 488 GGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSP 547

Query: 66  EAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEVEEPLS 125
           E   +PA       P  + P+     EE  S      P   ++  +E     +E + P  
Sbjct: 548 EKAKSPAKEEAKSPPEAKSPE----KEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEK 603

Query: 126 QESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPLS 185
            +S V+E     +E + P+ +E++    +    + + P  +E++  E  ++  E EE  S
Sbjct: 604 AKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEK-AKSPEKEEAKS 662

Query: 186 QESQVEEPPSQESEMEE 202
            E + + P   E++  E
Sbjct: 663 PE-KAKSPVKAEAKSPE 678



 Score = 53.5 bits (127), Expect = 1e-07
 Identities = 43/206 (20%), Positives = 82/206 (39%), Gaps = 10/206 (4%)

Query: 3   PKPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMAAV 62
           P   A+ P  +A    K ++ S      P+K+  K   + K+  + +   K  A      
Sbjct: 505 PAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEA 564

Query: 63  TAPEAESA--PAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEV 120
            +PE E A  PA     ++      +    P E  S      P+ +EA  + P   +S V
Sbjct: 565 KSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEA--KSPAEAKSPV 622

Query: 121 EEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEM 180
           +E     ++V+ P   +S  +E      + + P  ++ E + P   +S V+       + 
Sbjct: 623 KEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSP--EKEEAKSPEKAKSPVKAEAKSPEKA 680

Query: 181 EEPLSQESQVEE----PPSQESEMEE 202
           + P+  E++  E    P  +E++  E
Sbjct: 681 KSPVKAEAKSPEKAKSPVKEEAKSPE 706



 Score = 53.5 bits (127), Expect = 1e-07
 Identities = 47/226 (20%), Positives = 101/226 (44%), Gaps = 26/226 (11%)

Query: 2   SPKPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMAA 61
           SP+   S   A+A    K KS  +     P+K  + V ++ K+  + +   K  A     
Sbjct: 662 SPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEK 721

Query: 62  VTAP-----------------EAESAPAAPGPSDQPSQEL--PQHELPPEEPVSEGTQHD 102
             +P                 EA+S   A  P    + ++  P+ + P +E         
Sbjct: 722 AKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKF 781

Query: 103 PLSQEAELEEPLSQESEVEEPLSQESQV-EEPLSQESEVEEPLSQESQVEEPLSQESEVE 161
           P   ++ ++E +    + + PL ++++  E+ + ++ EV+ P+ +E   E+P  QE +V+
Sbjct: 782 PEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEE---EKP--QEVKVK 836

Query: 162 EPLSQESQVEEPLSQES-EMEEPLSQESQVEEPPSQESEMEELPSV 206
           EP  +  + + P + ++ E ++   +E+  +E P  + E ++ P+V
Sbjct: 837 EPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAV 882



 Score = 52.4 bits (124), Expect = 3e-07
 Identities = 47/214 (21%), Positives = 90/214 (42%), Gaps = 22/214 (10%)

Query: 11  PAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMAAVTAPEAESA 70
           P KA    K ++ S P    P+K+  K   + K+  + +   K  A   A   +PE   +
Sbjct: 547 PEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKS 606

Query: 71  PA-----APGPSDQPSQE---LPQHELPPEE---PVSEGTQHDPLSQEAELEEPLSQESE 119
           P      +P  +  P +E    P     PE+   P  E  +    ++  E EE  S E +
Sbjct: 607 PVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPE-K 665

Query: 120 VEEPLSQESQVEEPLSQ--ESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEE----P 173
            + P+  E++  E      ++E + P   +S V+E      + + P+ +E++  E    P
Sbjct: 666 AKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSP 725

Query: 174 LSQESEMEE----PLSQESQVEEPPSQESEMEEL 203
           + +E++  E    P+ +E++  E      + + L
Sbjct: 726 VKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTL 759



 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 46/229 (20%), Positives = 88/229 (38%), Gaps = 26/229 (11%)

Query: 2   SPKPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMAA 61
           SP    +  P KA    K ++ S      P+K  T   K  +A    +   +  A K   
Sbjct: 724 SPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPE 783

Query: 62  VTAPEAESAPAAPGPSDQPSQE---LPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQES 118
                 +    +P  +  P +E    P+ E+P +E V    + +   QE +++EP  +  
Sbjct: 784 KAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAE 843

Query: 119 EVEEPLSQESQV------------EEPLSQESEVEEPLSQ---ESQVEEPLSQES----- 158
           E + P + +++             E P  +  E +EP  +   ES+VE    +       
Sbjct: 844 EEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKV 903

Query: 159 ---EVEEPLSQESQVEEPLSQESEMEEPLSQESQVEEPPSQESEMEELP 204
              E E P   E + +    +++E+ +    +++ +EP     + E  P
Sbjct: 904 PTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAP 952



 Score = 41.2 bits (95), Expect = 6e-04
 Identities = 26/101 (25%), Positives = 52/101 (51%), Gaps = 1/101 (0%)

Query: 106 QEAELEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLS 165
           ++ ++ E   +E+ + E  ++E+QV E +++E E E    +  + E    +E+E  E  +
Sbjct: 442 EKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEET 501

Query: 166 QESQVEEPLSQESEMEEPLSQESQ-VEEPPSQESEMEELPS 205
           +    EE  S E E + P+ +E++   E  S E E  + P+
Sbjct: 502 KSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPA 542



 Score = 37.4 bits (85), Expect = 0.009
 Identities = 40/199 (20%), Positives = 86/199 (43%), Gaps = 26/199 (13%)

Query: 2   SPKPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMAA 61
           SP      P     +   +K+  + +P+ PK +  K +KK +A ++     K    K  A
Sbjct: 822 SPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPA 881

Query: 62  VTAPEAESAPAAPGPS-DQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEV 120
           V  P+     A    + D+     P+ E P +  V E  +               +++EV
Sbjct: 882 VEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKP-------------KEKTEV 928

Query: 121 EEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEM 180
            +    +++ +EP S+ +E +E   ++   +E  +++ E E+P ++    E+        
Sbjct: 929 AKKEPDDAKAKEP-SKPAEKKEAAPEKKDTKEEKAKKPE-EKPKTEAKAKED-------- 978

Query: 181 EEPLSQESQVEEPPSQESE 199
           ++ LS+E    +P ++++E
Sbjct: 979 DKTLSKEP--SKPKAEKAE 995



 Score = 37.0 bits (84), Expect = 0.012
 Identities = 26/100 (26%), Positives = 50/100 (50%), Gaps = 5/100 (5%)

Query: 103 PLSQEAELEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEE 162
           P S    L +  S  + ++    ++ +V E   +E+ + E  ++E+QV E +++E E +E
Sbjct: 419 PFSLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEE-KE 477

Query: 163 PLSQESQVEEPLSQESEMEEPLSQESQVEEPPSQESEMEE 202
              +E + EE      E EE    E + + PP++E+   E
Sbjct: 478 AKEEEGKEEE----GGEEEEAEGGEEETKSPPAEEAASPE 513


>gi|16445033 ACRC protein [Homo sapiens]
          Length = 691

 Score = 58.2 bits (139), Expect = 5e-09
 Identities = 32/138 (23%), Positives = 66/138 (47%)

Query: 65  PEAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEVEEPL 124
           P+  S  ++   SD  S +       P++   +    D  S ++++ +  S +SE  +  
Sbjct: 189 PDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDS 248

Query: 125 SQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPL 184
           S +S+  +  S +SE  +  S +S+  +  S +SE  +  S +S+  +  S +SE  +  
Sbjct: 249 SDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDK 308

Query: 185 SQESQVEEPPSQESEMEE 202
           S +S V E  S +S++ +
Sbjct: 309 SDDSDVPEDKSDDSDVPD 326



 Score = 54.3 bits (129), Expect = 7e-08
 Identities = 30/136 (22%), Positives = 62/136 (45%)

Query: 64  APEAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEVEEP 123
           AP+  S  +     +    ++P          +     D  S ++++ +  S +S+V + 
Sbjct: 168 APDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDD 227

Query: 124 LSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEP 183
            S +S V +  S +SE  +  S +S+  +  S +SE  +  S +S+  +  S +SE  + 
Sbjct: 228 SSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDD 287

Query: 184 LSQESQVEEPPSQESE 199
            S +S+  +  S +SE
Sbjct: 288 SSDDSEASDDSSDDSE 303



 Score = 53.5 bits (127), Expect = 1e-07
 Identities = 30/124 (24%), Positives = 61/124 (49%), Gaps = 1/124 (0%)

Query: 77  SDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEVEEPLSQESQVEEPLSQ 136
           SD P  +    ++P ++   +    D  S ++E  +  S +SE  +  S +S+  +  S 
Sbjct: 212 SDVPDDKSDDSDVP-DDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSD 270

Query: 137 ESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPLSQESQVEEPPSQ 196
           +SE  +  S +S+  +  S +SE  +  S +S+  +  S +S++ E  S +S V +  S 
Sbjct: 271 DSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSD 330

Query: 197 ESEM 200
           + E+
Sbjct: 331 DLEV 334



 Score = 50.8 bits (120), Expect = 8e-07
 Identities = 29/117 (24%), Positives = 56/117 (47%), Gaps = 1/117 (0%)

Query: 77  SDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEVEEPLSQESQVEEPLSQ 136
           SD P       ++P ++   +    D  S ++E  +  S +SE  +  S +S+  +  S 
Sbjct: 222 SDVPDDSSDDSDVP-DDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSD 280

Query: 137 ESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPLSQESQVEEP 193
           +SE  +  S +S+  +  S +SE  +  S +S V E  S +S++ +  S + +V  P
Sbjct: 281 DSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVP 337



 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 32/126 (25%), Positives = 56/126 (44%), Gaps = 1/126 (0%)

Query: 77  SDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEVEEPLSQESQVEEPLSQ 136
           SD P       E P ++   +    D  S ++E  +  S +SE  +  S +S+  +  S 
Sbjct: 232 SDVPDDSSDDSEAP-DDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSD 290

Query: 137 ESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPLSQESQVEEPPSQ 196
           +SE  +  S +S+  +  S +S+V E  S +S V +  S + E+  P        +  S 
Sbjct: 291 DSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASD 350

Query: 197 ESEMEE 202
           E E+ E
Sbjct: 351 EEELVE 356



 Score = 50.1 bits (118), Expect = 1e-06
 Identities = 29/139 (20%), Positives = 60/139 (43%)

Query: 64  APEAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEVEEP 123
           AP+  S  +     +    E P       +   + +         +  +  S +S+V + 
Sbjct: 158 APDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDD 217

Query: 124 LSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEP 183
            S +S V +  S +S+V +  S +S+  +  S +SE  +  S +S+  +  S +SE  + 
Sbjct: 218 KSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDD 277

Query: 184 LSQESQVEEPPSQESEMEE 202
            S +S+  +  S +SE  +
Sbjct: 278 SSDDSEASDDSSDDSEASD 296



 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 28/139 (20%), Positives = 57/139 (41%)

Query: 64  APEAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEVEEP 123
           AP+  S  +     +    E P       E   + +    +  +   +       +  + 
Sbjct: 148 APDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDD 207

Query: 124 LSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEP 183
            S +S V +  S +S+V +  S +S V +  S +SE  +  S +S+  +  S +SE  + 
Sbjct: 208 NSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDD 267

Query: 184 LSQESQVEEPPSQESEMEE 202
            S +S+  +  S +SE  +
Sbjct: 268 SSDDSEAPDDSSDDSEASD 286



 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 31/135 (22%), Positives = 64/135 (47%), Gaps = 9/135 (6%)

Query: 77  SDQPSQELPQHELPPEEP---VSEGTQHDPLSQEAELEEPLSQESEVEEPLSQESQVEEP 133
           SD  S E    +   +EP   +S+    D    + E+ +  S +SE  +  S +S+  + 
Sbjct: 102 SDDESPECCHVKPAIQEPPIVISDDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDD 161

Query: 134 LSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVE------EPLSQESEMEEPLSQE 187
            S +SE  +  S +S+  +  S +S+V +  S +S  +      +  S +S++ +  S +
Sbjct: 162 NSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDD 221

Query: 188 SQVEEPPSQESEMEE 202
           S V +  S +S++ +
Sbjct: 222 SDVPDDSSDDSDVPD 236



 Score = 28.1 bits (61), Expect = 5.5
 Identities = 20/81 (24%), Positives = 33/81 (40%), Gaps = 9/81 (11%)

Query: 5   PRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRR---------GKKGA 55
           P    P     ++GKRKS ++     P+K+ TK     +  R+ +           K+ A
Sbjct: 398 PTEEEPAPVVEQSGKRKSKTKTIVEPPRKRQTKTKNIVEPPRKRQTKTKNIVEPLRKRKA 457

Query: 56  ATKMAAVTAPEAESAPAAPGP 76
            TK  +VT    +  P+   P
Sbjct: 458 KTKNVSVTPGHKKRGPSKKKP 478


>gi|155030232 proline, glutamic acid and leucine rich protein 1
           [Homo sapiens]
          Length = 1130

 Score = 57.8 bits (138), Expect = 6e-09
 Identities = 48/139 (34%), Positives = 63/139 (45%), Gaps = 19/139 (13%)

Query: 66  EAESAPAAPGPSDQPSQELPQHE----LPPEEPVSEGTQHDPLSQEAELEEPLS------ 115
           E E  PAAPGP   P    P       LPP + V EGT          LEE L+      
Sbjct: 828 EPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQLVPEGTPGG--GGPPALEEDLTVININS 885

Query: 116 --QESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEP 173
             +E E EE   +E + EE   +E + EE   +E   EE   +E E EE   +E + EE 
Sbjct: 886 SDEEEEEEE--EEEEEEEEEEEEEEDFEE---EEEDEEEYFEEEEEEEEEFEEEFEEEEG 940

Query: 174 LSQESEMEEPLSQESQVEE 192
             +E E EE   +E ++EE
Sbjct: 941 ELEEEEEEEDEEEEEELEE 959



 Score = 36.2 bits (82), Expect = 0.020
 Identities = 34/119 (28%), Positives = 49/119 (41%), Gaps = 8/119 (6%)

Query: 85   PQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPL 144
            P   LPP  P  E     P   + E E       EVEEP ++E +  +  +  +   E L
Sbjct: 978  PPPTLPPALPPPES----PPKVQPEPEPEPGLLLEVEEPGTEEERGAD--TAPTLAPEAL 1031

Query: 145  SQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPLSQESQVEEPPSQESEMEEL 203
              + +VE     ES    P  QE   EEP +  + +EE     S   +PP +    EE+
Sbjct: 1032 PSQGEVER--EGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEM 1088



 Score = 34.3 bits (77), Expect = 0.077
 Identities = 44/204 (21%), Positives = 72/204 (35%), Gaps = 14/204 (6%)

Query: 5    PRASGPPAKATEAGKRKSSSQ-----PSPSDPKKKTTKVAKKGKAVRRGRRGKKGAAT-- 57
            P  + PP  A E  +   ++      P P  P           + V  G  G  G     
Sbjct: 816  PPTASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPALE 875

Query: 58   ---KMAAVTAPEAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPL 114
                +  + + + E         ++  +E  + +   EE   E    +   +E E EE  
Sbjct: 876  EDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEF 935

Query: 115  SQES-EVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEP 173
             +E  E+EE   +E + EE   +E E  E  +   +VEE       +   L      E P
Sbjct: 936  EEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPP---ESP 992

Query: 174  LSQESEMEEPLSQESQVEEPPSQE 197
               + E E       +VEEP ++E
Sbjct: 993  PKVQPEPEPEPGLLLEVEEPGTEE 1016


>gi|4506879 selectin P ligand [Homo sapiens]
          Length = 402

 Score = 56.6 bits (135), Expect = 1e-08
 Identities = 40/191 (20%), Positives = 81/191 (42%), Gaps = 9/191 (4%)

Query: 10  PPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMAAV--TAPEA 67
           P +   E   R+S+   +     + TT++A  G            AA ++      A EA
Sbjct: 78  PESTTVEPAARRSTGLDAGGAVTELTTELANMGNL------STDSAAMEIQTTQPAATEA 131

Query: 68  ESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEVEEPLSQE 127
           ++ P A   +        + +  P    +E     P + EA+  +P   E++   P + E
Sbjct: 132 QTTPLAATEAQTTRLTATEAQTTPLA-ATEAQTTPPAATEAQTTQPTGLEAQTTAPAAME 190

Query: 128 SQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPLSQE 187
           +Q   P + E++   P + E+Q  +  + E++   P + E+Q  +P + E++     + E
Sbjct: 191 AQTTAPAAMEAQTTPPAAMEAQTTQTTAMEAQTTAPEATEAQTTQPTATEAQTTPLAAME 250

Query: 188 SQVEEPPSQES 198
           +   EP + E+
Sbjct: 251 ALSTEPSATEA 261



 Score = 53.5 bits (127), Expect = 1e-07
 Identities = 33/135 (24%), Positives = 63/135 (46%), Gaps = 11/135 (8%)

Query: 62  VTAPEAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEVE 121
           +TA EA++ P A   +            PP    ++ TQ  P   EA+   P + E++  
Sbjct: 146 LTATEAQTTPLAATEAQTT---------PPAATEAQTTQ--PTGLEAQTTAPAAMEAQTT 194

Query: 122 EPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEME 181
            P + E+Q   P + E++  +  + E+Q   P + E++  +P + E+Q     + E+   
Sbjct: 195 APAAMEAQTTPPAAMEAQTTQTTAMEAQTTAPEATEAQTTQPTATEAQTTPLAAMEALST 254

Query: 182 EPLSQESQVEEPPSQ 196
           EP + E+   EP ++
Sbjct: 255 EPSATEALSMEPTTK 269



 Score = 52.4 bits (124), Expect = 3e-07
 Identities = 28/130 (21%), Positives = 60/130 (46%), Gaps = 11/130 (8%)

Query: 88  ELPPEEPVSEGTQHDPLSQ-----------EAELEEPLSQESEVEEPLSQESQVEEPLSQ 136
           E+   +P +   Q  PL+            EA+     + E++   P + E+Q  +P   
Sbjct: 120 EIQTTQPAATEAQTTPLAATEAQTTRLTATEAQTTPLAATEAQTTPPAATEAQTTQPTGL 179

Query: 137 ESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPLSQESQVEEPPSQ 196
           E++   P + E+Q   P + E++   P + E+Q  +  + E++   P + E+Q  +P + 
Sbjct: 180 EAQTTAPAAMEAQTTAPAAMEAQTTPPAAMEAQTTQTTAMEAQTTAPEATEAQTTQPTAT 239

Query: 197 ESEMEELPSV 206
           E++   L ++
Sbjct: 240 EAQTTPLAAM 249



 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 21/98 (21%), Positives = 47/98 (47%)

Query: 102 DPLSQEAELEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVE 161
           D  + E +  +P + E++     + E+Q     + E++     + E+Q   P + E++  
Sbjct: 115 DSAAMEIQTTQPAATEAQTTPLAATEAQTTRLTATEAQTTPLAATEAQTTPPAATEAQTT 174

Query: 162 EPLSQESQVEEPLSQESEMEEPLSQESQVEEPPSQESE 199
           +P   E+Q   P + E++   P + E+Q   P + E++
Sbjct: 175 QPTGLEAQTTAPAAMEAQTTAPAAMEAQTTPPAAMEAQ 212


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 54.3 bits (129), Expect = 7e-08
 Identities = 61/218 (27%), Positives = 88/218 (40%), Gaps = 18/218 (8%)

Query: 3     PKPR-ASGPPAKATEAGKRKSSSQPSPSDPKKKTT----KVAKKGKAVRRGRRGKKGAAT 57
             P P+    PPAK  E  K+    +  P+   KK      KV KK + V       +    
Sbjct: 10048 PAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEV 10107

Query: 58    KMAAVTAPEAESAPAAPGPSDQPSQELPQHE--LPPEEPVSEGTQHDPLSQE-AELEEPL 114
                    PE E  P       +  + LP+ E  LP EE +    +  P  +E    EE  
Sbjct: 10108 LFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEF 10167

Query: 115   SQESEVEEPLSQESQVEEPLSQ------ESEVEEPLSQESQVEEPLSQESEVEEP---LS 165
               E EV   +  +  V  P+ +      E +V  P  +E+   +      +VEE    L 
Sbjct: 10168 VPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILP 10227

Query: 166   QESQVEEPLSQESEMEEPLSQESQVEEPPSQESEMEEL 203
             +E +V      E   EEP+S+E   EEPPS E E+EE+
Sbjct: 10228 KEEEVLPVEVTEEPEEEPISEEEIPEEPPSIE-EVEEV 10264



 Score = 51.2 bits (121), Expect = 6e-07
 Identities = 54/213 (25%), Positives = 86/213 (40%), Gaps = 18/213 (8%)

Query: 3     PKPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMAAV 62
             P+ +   PPAK  EA   K    P    P+KK      K   V   +        ++   
Sbjct: 10506 PEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTK------VPEVPKA 10559

Query: 63    TAPEAESAPAAPGPSDQPSQELPQ--HELPPEEPVSEGTQHDPLSQEAEL-EEPLSQESE 119
               PE +   A P   + P  E+P+   E+ PE+ V       P     ++ E P     E
Sbjct: 10560 AVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPE 10619

Query: 120   VEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESE------VEEPLSQESQVEEP 173
              + P+    + E P ++  EV +    E +V E +  + E       EEP  +E  +EEP
Sbjct: 10620 KKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEP--EEVALEEP 10677

Query: 174   LSQESEMEEPLSQESQVEEPPSQESEMEELPSV 206
              ++  E  EP +   QV  PP +    ++ P+V
Sbjct: 10678 PAEVVEEPEP-AAPPQVTVPPKKPVPEKKAPAV 10709



 Score = 49.3 bits (116), Expect = 2e-06
 Identities = 63/221 (28%), Positives = 92/221 (41%), Gaps = 33/221 (14%)

Query: 6     RASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMAAVTAP 65
             +   PPAK  E  K+     P    PKK+    AK  +        KK    +   V  P
Sbjct: 9970  KKEAPPAKVPEVPKKPEEKVPVLI-PKKEKPPPAKVPEVP------KKPVPEEKVPVPVP 10022

Query: 66    EAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEVEEPLS 125
             +   AP A  P + P + +P+ ++P   P        P ++  E+ + L  E +   P+ 
Sbjct: 10023 KKVEAPPAKVP-EVPKKPVPEKKVPVPAPKKVEA---PPAKVPEVPKKLIPEEKKPTPVP 10078

Query: 126   QESQVEEPLSQESEVEEP------LSQESQV--EEPLSQESEV----EEPLSQESQV--- 170
             ++  VE P  +  +  EP      L QE +V  EE +  E EV    EE L +E +V   
Sbjct: 10079 KK--VEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPE 10136

Query: 171   -EEPLSQESEM----EEPLSQESQVEEPPSQESEMEELPSV 206
              EE L +E E+    EE   +E  V E      E E LP V
Sbjct: 10137 EEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEV 10177



 Score = 47.8 bits (112), Expect = 7e-06
 Identities = 49/213 (23%), Positives = 81/213 (38%), Gaps = 17/213 (7%)

Query: 5     PRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMAAVTA 64
             P+   PP +  EA K     +  P+ P KK          V+     K+    K   V  
Sbjct: 10572 PKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTP-----VKVPEAPKEVVPEKKVPVPP 10626

Query: 65    PEAESAPAAPGPSDQPSQELPQHELP---PEEPVSEGTQHDPLSQEAELEEPLSQESEVE 121
             P+    P    P + P   +P+ ++P   P +P S   +     +E  LEEP ++  E  
Sbjct: 10627 PKKPEVPPTKVP-EVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEP 10685

Query: 122   EPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQV--------EEP 173
             EP +       P     E + P     + E P  +  EV + +  E +V        E P
Sbjct: 10686 EPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAP 10745

Query: 174   LSQESEMEEPLSQESQVEEPPSQESEMEELPSV 206
              ++  E+ + +  E +V  P   E    ++P V
Sbjct: 10746 PAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEV 10778



 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 58/235 (24%), Positives = 89/235 (37%), Gaps = 34/235 (14%)

Query: 6     RASGPPAKATEAGKR----KSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMAA 61
             +   PPAK  E  K+    K    P+P   +    KV +  K +    +       K+ A
Sbjct: 10024 KVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEA 10083

Query: 62    VTAPEAESAPAAPGPSDQPSQE--------LPQHELPPEEPVSEGTQHDPLSQEAEL--- 110
                   +     P P   P +E        +P+ E+ PEE      + + L +E E+   
Sbjct: 10084 PPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPE 10143

Query: 111   EEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQ------ESEVEEPL 164
             EE +  E E   P  +    EE    E EV   +  +  V  P+ +      E +V  P 
Sbjct: 10144 EEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPK 10203

Query: 165   SQES----------QVEEP---LSQESEMEEPLSQESQVEEPPSQESEMEELPSV 206
              +E+          +VEE    L +E E+      E   EEP S+E   EE PS+
Sbjct: 10204 KEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSI 10258



 Score = 45.1 bits (105), Expect = 4e-05
 Identities = 56/220 (25%), Positives = 91/220 (41%), Gaps = 35/220 (15%)

Query: 10    PPAKATEAGKRKSSSQPS-----PSDPKKKTTKVAKKGKA--VRRGRRGKKGAATKMAAV 62
             PPA+  E  +  +  Q +     P   KK    VAKK +   V+     K+    K   +
Sbjct: 10677 PPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPL 10736

Query: 63    TAPEAESAPAAPGPSDQPSQELPQH--------ELPP-------EEPVSEGTQHDPLSQE 107
               P+   AP A  P + P + +P+         E+PP       ++PV E     P+ + 
Sbjct: 10737 VVPKKPEAPPAKVP-EVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPER 10795

Query: 108   AE------LEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVE 161
             AE       EEP  +E   EE ++ E +   P+++E E E P    +  EEP     E +
Sbjct: 10796 AESPPPEVYEEP--EEIAPEEEIAPEEEKPVPVAEEEEPEVP--PPAVPEEPKKIIPEKK 10851

Query: 162   EPLSQESQVEEPLSQESE--MEEPLSQESQVEEPPSQESE 199
              P+ ++ +   P   E E  +E+P  +      PP+   E
Sbjct: 10852 VPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKE 10891



 Score = 38.5 bits (88), Expect = 0.004
 Identities = 45/203 (22%), Positives = 79/203 (38%), Gaps = 14/203 (6%)

Query: 3    PKPRASGPPAKATEAGKRKSSSQPSPSDPKKKTT-KVAKKGKAVRRGRRGKKGAATK--- 58
            P+ +   P  K  +    K   +P    P+KK   KV K  + +      +    T+   
Sbjct: 9589 PEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEEK 9648

Query: 59   -MAAVTAPEAESAPAAPG------PSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELE 111
             + AVT  EA      P       P ++  +  P+ E  P   V+E  +     ++  +E
Sbjct: 9649 VLVAVTKKEAPPKARVPEEPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEEKVSIE 9708

Query: 112  EPLSQESEVEE-PLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQV 170
             P  +   ++E  + +E +    L +E+   +   +  + EE   +E E  EP  +  Q 
Sbjct: 9709 APKREPQPIKEVTIMEEKERAYTLEEEAVSVQREEEYEEYEEYDYKEFEEYEPTEEYDQY 9768

Query: 171  EEPLSQESEMEEPLSQESQVEEP 193
            EE   +E E E     E  + EP
Sbjct: 9769 EE--YEEREYERYEEHEEYITEP 9789



 Score = 38.1 bits (87), Expect = 0.005
 Identities = 52/200 (26%), Positives = 85/200 (42%), Gaps = 25/200 (12%)

Query: 6    RASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMAAVTAP 65
            R   PP    E  K+K   +  P   K++      K  A+      KK    +  AV  P
Sbjct: 9391 REESPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPALP-----KKPVPEEKVAVPVP 9445

Query: 66   EAESAPAAPGPSDQPSQELPQHELPPEEPVS-------EGTQHDPLSQE----AELEEPL 114
             A+ AP  P         + +     EE +S       E T+H+  ++E    +E EE +
Sbjct: 9446 VAKKAPP-PRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEGV 9504

Query: 115  SQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPL 174
            S     EE   +E + E  +++   +EEP  +E  VEE L   S+  E  ++ ++V E  
Sbjct: 9505 SISVYREEEREEEEEAE--VTEYEVMEEP--EEYVVEEKLHIISKRVE--AEPAEVTE-- 9556

Query: 175  SQESEMEEPLSQESQVEEPP 194
             QE ++       +++EEPP
Sbjct: 9557 RQEKKIVLKPKIPAKIEEPP 9576



 Score = 37.0 bits (84), Expect = 0.012
 Identities = 64/265 (24%), Positives = 98/265 (36%), Gaps = 73/265 (27%)

Query: 4     KPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMAAVT 63
             KP A  PPAK  E  K +   +   + PKK     AK  +        KK    +  AV 
Sbjct: 10741 KPEA--PPAKVPEVPK-EVVPEKKVAVPKKPEVPPAKVPEVP------KKPVLEEKPAVP 10791

Query: 64    APE-AESAPAAPGPSDQPSQELPQHELPPEE--PVSEGTQHDP-LSQEAELEEPLSQESE 119
              PE AES P  P   ++P +  P+ E+ PEE  PV    + +P +   A  EEP     E
Sbjct: 10792 VPERAESPP--PEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPE 10849

Query: 120   VEEPLSQESQVEEPLSQESE--VEEP-LSQESQVEEPLSQESEVEEPLSQESQV------ 170
              + P+ ++ +   P   E E  +E+P L        P   + +V+E + Q   +      
Sbjct: 10850 KKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVP 10909

Query: 171   EEP----------------------------------------LSQESEMEEPLSQESQV 190
             E+P                                        L +  E EEP  +  ++
Sbjct: 10910 EKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKL 10969

Query: 191   EE---------PPSQESEMEELPSV 206
             E+         PP +  E  E+P+V
Sbjct: 10970 EKVKKPAVPEPPPPKPVEEVEVPTV 10994



 Score = 35.8 bits (81), Expect = 0.026
 Identities = 52/202 (25%), Positives = 83/202 (41%), Gaps = 23/202 (11%)

Query: 4    KPRASGPPAKATE-AGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMAAV 62
            KP+A  PPAK  + A   +    P P   K    KV ++ K V   +        +   V
Sbjct: 9806 KPKA--PPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKVFEEKIRISITKREKEQV 9863

Query: 63   TAPEAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEVEE 122
            T P A+          +    +P+ E+ P   V E      + +E E EE   +E  V  
Sbjct: 9864 TEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPE------VPKELEPEEVAFEEEVV-- 9915

Query: 123  PLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEE 182
                 + VEE L +E   EE + +E   EE +++E  V  P+      E P     E ++
Sbjct: 9916 -----THVEEYLVEEE--EEYIHEE---EEFITEEEVV--PVIPVKVPEVPRKPVPEEKK 9963

Query: 183  PLSQESQVEEPPSQESEMEELP 204
            P+    + E PP++  E+ + P
Sbjct: 9964 PVPVPKKKEAPPAKVPEVPKKP 9985



 Score = 35.4 bits (80), Expect = 0.034
 Identities = 45/142 (31%), Positives = 66/142 (46%), Gaps = 22/142 (15%)

Query: 62    VTAPEAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEVE 121
             V  P+ E AP A  P      E  +  LP EE V              L   +++E E E
Sbjct: 10199 VVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEV--------------LPVEVTEEPE-E 10243

Query: 122   EPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEM- 180
             EP+S+E   EEP S E EVEE      +V E + +++  E P     +VE P ++ S+  
Sbjct: 10244 EPISEEEIPEEPPSIE-EVEE--VAPPRVPEVI-KKAVPEAPTPVPKKVEAPPAKVSKKI 10299

Query: 181   -EEPLSQESQVEE-PPSQESEM 200
              EE +    Q +E PP++  E+
Sbjct: 10300 PEEKVPVPVQKKEAPPAKVPEV 10321



 Score = 33.1 bits (74), Expect = 0.17
 Identities = 32/153 (20%), Positives = 65/153 (42%), Gaps = 11/153 (7%)

Query: 52   KKGAATKMAAVTAPEAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELE 111
            +K A  ++A V  P+    PA   P      E+P+  +P E+      + +P +     E
Sbjct: 9293 EKPAPEEVAPVPIPKKVEPPAPKVP------EVPKKPVPEEKKPVPVPKKEPAAPPKVPE 9346

Query: 112  EPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVE 171
             P     E + P+    + E P ++  EV++ +  E ++   ++Q  E   P    +  E
Sbjct: 9347 VPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKI-TIVTQREESPPP----AVPE 9401

Query: 172  EPLSQESEMEEPLSQESQVEEPPSQESEMEELP 204
             P  +  E  +P+ ++ +   PP +   + + P
Sbjct: 9402 IPKKKVPEERKPVPRKEEEVPPPPKVPALPKKP 9434



 Score = 33.1 bits (74), Expect = 0.17
 Identities = 33/139 (23%), Positives = 58/139 (41%), Gaps = 20/139 (14%)

Query: 66    EAESAPAAPGPSDQPS-QELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEVEEPL 124
             EAE       P   P   E+ +  +PP++P ++             +EP ++  EV + +
Sbjct: 10426 EAEEVEVFEKPKAPPKGPEISEKIIPPKKPPTKVVPR---------KEPPAKVPEVPKKI 10476

Query: 125   SQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEE---PLSQESQVEEPLSQESEME 181
               E +V  P       EEP    ++V E L  +  V E   P+    + E P  +  E  
Sbjct: 10477 VVEEKVRVP-------EEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAP 10529

Query: 182   EPLSQESQVEEPPSQESEM 200
             + +  E +V  PP ++ E+
Sbjct: 10530 KEVVPEKKVPVPPPKKPEV 10548



 Score = 29.3 bits (64), Expect = 2.5
 Identities = 39/184 (21%), Positives = 73/184 (39%), Gaps = 17/184 (9%)

Query: 4     KPRASGPPAKATEAGKRKSSSQPSPSDPKK-KTTKVAKKGKAVRRGRRGKKGAATKMAAV 62
             +P    P  +  +  K K  + P P  PK  +  +V    K  R+     K    K  A+
Sbjct: 10956 RPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIK-PAI 11014

Query: 63    TAPEAESAPAAPGPSDQPSQELPQHELPPEE----PVSEGTQHDPLSQEAELEEPLSQES 118
               P       AP P  +P  E+   + PP E    P++       + ++AE + P  + +
Sbjct: 11015 PLP-------APEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAA 11067

Query: 119   EVEEPL-SQESQVEEPLSQESEVEEPLS--QESQVEEPLSQESEVEEPLSQESQVEEPLS 175
             + + P+     +   P+  E     P S  ++   E P + + +   PL    ++++ + 
Sbjct: 11068 KPKGPIKGVPKKTPSPIEAERRKLRPGSGGEKPPDEAPFTYQLKA-VPLKFVKEIKDIIL 11126

Query: 176   QESE 179
              ESE
Sbjct: 11127 TESE 11130


>gi|239745855 PREDICTED: hypothetical protein XP_002343606 [Homo
           sapiens]
          Length = 870

 Score = 54.3 bits (129), Expect = 7e-08
 Identities = 38/130 (29%), Positives = 60/130 (46%), Gaps = 4/130 (3%)

Query: 68  ESAPAAPGPSDQPSQELPQHELPPEEP-VSEGTQHDP--LSQEAELEEPLSQESEVEEPL 124
           + APA P  S   S  LP HE+  + P   +   H P    + A++E  ++ E    E  
Sbjct: 259 QEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEP-TNETE 317

Query: 125 SQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPL 184
           S ++Q E P+    EVE   +Q+    EP     E E  +S++ Q  +P     E+E  L
Sbjct: 318 SSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPMEHELSISEQQQPVQPSESSREVESSL 377

Query: 185 SQESQVEEPP 194
           +Q+    +PP
Sbjct: 378 TQQETPGQPP 387



 Score = 32.7 bits (73), Expect = 0.22
 Identities = 32/122 (26%), Positives = 50/122 (40%), Gaps = 6/122 (4%)

Query: 86  QHELPPEEPVSEGTQHDPLS--QEAELEEPLSQESEVEEPLSQESQVEEPLSQESEVEEP 143
           QH  PP  P S   +  PL+  QE   + P    +E   P  QE+  E P + E      
Sbjct: 455 QHGGPPLLPESS-EEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSL 513

Query: 144 LSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPLSQESQVEEPPSQESEMEEL 203
             QE+  + P      V +P  + S + +   Q  ++   ++ ES  E   S    M+E 
Sbjct: 514 THQEAPAQTPEFPNVVVAQP-PEHSHLTQATVQPLDLGFTITPESMTEVELS--PTMKET 570

Query: 204 PS 205
           P+
Sbjct: 571 PT 572



 Score = 31.2 bits (69), Expect = 0.65
 Identities = 33/129 (25%), Positives = 49/129 (37%), Gaps = 10/129 (7%)

Query: 88  ELPPEEPVSEGTQHDPLSQEAELEEPLSQESEV--EEPLSQESQVE------EPLSQESE 139
           +L   +   +  Q++  S +      L  E  V  +EP     QV       EP +Q  E
Sbjct: 169 QLSTPQSQKQTLQNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPE 228

Query: 140 VEEPLSQES-QVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPLSQESQVE-EPPSQE 197
             E +   S Q E P      +EE  S   Q    L  ES ME       +V  +PP ++
Sbjct: 229 TLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGED 288

Query: 198 SEMEELPSV 206
                LP++
Sbjct: 289 QAYYHLPNI 297


>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
          Length = 2400

 Score = 54.3 bits (129), Expect = 7e-08
 Identities = 53/171 (30%), Positives = 76/171 (44%), Gaps = 26/171 (15%)

Query: 55   AATKMAAVTAPEAE-----------------SAPAAPGPSDQPSQELPQHELPPE-EPVS 96
            A  +   V APEAE                  AP A G +   S+++   E   E +P S
Sbjct: 1844 AQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPES 1903

Query: 97   EGTQHDPLSQEAELE----EPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEE 152
            EG +     +EA+ E    E L  E E +EP S+ ++ +E      E E     ES+V E
Sbjct: 1904 EGAEAPEAEKEAQPETESVEALETEGE-DEPESEGAEAQEAEEAAQEAEGQTQPESEVIE 1962

Query: 153  PLSQESEVE-EPLSQESQVEEPLSQESEMEEPLSQESQVEEPPSQESEMEE 202
              SQE+E E +P S++ +  E   +  E E     ES+  E P  E EM+E
Sbjct: 1963 --SQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQE 2011



 Score = 52.4 bits (124), Expect = 3e-07
 Identities = 46/198 (23%), Positives = 79/198 (39%), Gaps = 5/198 (2%)

Query: 10   PPAKATEAGKRKSSSQPSPSDPKKKTTK--VAKKGKAVRRGRRGKKGAA-TKMAAVTAPE 66
            P ++  EA + +  +QP   D +    +  V  + +        K+    T+       E
Sbjct: 1869 PESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETE 1928

Query: 67   AESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEVEEPLSQ 126
             E  P + G   Q ++E  Q      +P SE  +     +EA+ E    +  EVE    +
Sbjct: 1929 GEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQE 1988

Query: 127  ESQVEEPLSQESEVEEPLSQESQVEEPLSQESE-VE-EPLSQESQVEEPLSQESEMEEPL 184
                 +P S++ E  E   +  + EE    ES+ VE +P S+  + +E   +  + E   
Sbjct: 1989 AEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDA 2048

Query: 185  SQESQVEEPPSQESEMEE 202
              ES   E P  E E +E
Sbjct: 2049 QPESDGVEAPEAEEEAQE 2066



 Score = 47.4 bits (111), Expect = 9e-06
 Identities = 43/154 (27%), Positives = 66/154 (42%), Gaps = 15/154 (9%)

Query: 54   GAATKMAAVTAPEAES----------APAAPGPSDQPSQELPQHELPPEEPVSEGTQHDP 103
            G +     + APEAE           AP A G + +   E        E P +EG +  P
Sbjct: 1827 GQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEG-EAQP 1885

Query: 104  LSQEAELEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEP 163
             S++ E  E    E + E   ++  + E+    E+E  E L  E + +EP S+ +E +E 
Sbjct: 1886 ESEDVETPE-AEWEVQPESEGAEAPEAEKEAQPETESVEALETEGE-DEPESEGAEAQEA 1943

Query: 164  LSQESQVEEPLSQESEMEEPLSQESQVEEPPSQE 197
                 + E     ESE+ E  SQE++ E  P  E
Sbjct: 1944 EEAAQEAEGQTQPESEVIE--SQEAEEEAQPESE 1975



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 48/208 (23%), Positives = 81/208 (38%), Gaps = 17/208 (8%)

Query: 10   PPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMAAVTAPEAE- 68
            P ++  EA + +  +QP     +   T+   + ++     +  + AA +    T PE+E 
Sbjct: 1901 PESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEV 1960

Query: 69   ------SAPAAPGPSDQPSQELP------QHELPPEEPVSEGTQHDPLSQEAELEEPLSQ 116
                     A P   D  + E+       + E  PE    E  + +   QEAE E     
Sbjct: 1961 IESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPES 2020

Query: 117  ESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQ 176
            +    +P S+  + +E   +  + E     ES   E    E E +E   +  + E     
Sbjct: 2021 DGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHP 2080

Query: 177  ESEMEEPLSQESQVEEPPSQESEMEELP 204
            ESE  +  +QE++ E  P  ESE  E P
Sbjct: 2081 ESEDVD--AQEAEGEAQP--ESEGVEAP 2104



 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 40/165 (24%), Positives = 65/165 (39%), Gaps = 13/165 (7%)

Query: 53   KGAATKMAAVTAPEAES----------APAAPGPSDQPSQELPQHELPPE-EPVSEGTQH 101
            +G A K   + APE E           AP A G +   S+ +   +   E +P SEG + 
Sbjct: 2107 EGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEA 2166

Query: 102  DPLSQEAELEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLS--QESQVEEPLSQESE 159
                +EA+ E    +  E E     ES+  E    E E +  L   +  + EE    E E
Sbjct: 2167 QEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPE 2226

Query: 160  VEEPLSQESQVEEPLSQESEMEEPLSQESQVEEPPSQESEMEELP 204
              E    E + +     E++ E+  S +  + +  S+E+     P
Sbjct: 2227 GVETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASESSSP 2271



 Score = 42.0 bits (97), Expect = 4e-04
 Identities = 45/207 (21%), Positives = 77/207 (37%), Gaps = 13/207 (6%)

Query: 4    KPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMAAVT 63
            +P++ G  A+  E   +K+     P     +  +  ++ +         +G   +     
Sbjct: 2026 QPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEA-------EGEVQEAEGEA 2078

Query: 64   APEAESAPA--APGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEVE 121
             PE+E   A  A G +   S+ +   E   E   +EG +      EA+ E    +  E E
Sbjct: 2079 HPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAE 2138

Query: 122  EPLSQESQVEEPLSQESEVE---EPLSQESQVEEPLSQESEVEEPLSQ-ESQVEEPLSQE 177
                 ES+  E    E E +   E +  +   EE   +   VE P ++ E+Q E    + 
Sbjct: 2139 GEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEA 2198

Query: 178  SEMEEPLSQESQVEEPPSQESEMEELP 204
             E E     E +  E P  E E +  P
Sbjct: 2199 PEAEGEAQPELEGVEAPEAEEEAQPEP 2225



 Score = 42.0 bits (97), Expect = 4e-04
 Identities = 52/203 (25%), Positives = 81/203 (39%), Gaps = 19/203 (9%)

Query: 10   PPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMAAVTAPEAES 69
            P +   EA + +  +Q +  + ++   +   + + V   +  +  A  +   V APEAE 
Sbjct: 2050 PESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVD-AQEAEGEAQPESEGVEAPEAEG 2108

Query: 70   ---------APAAPGPSDQPSQELPQHELPPE-EPVSEGTQHDPLSQEAELEEPLSQESE 119
                     AP   G +   S+ +   E   E +P SEG +      EA+ E    +  E
Sbjct: 2109 EAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQE 2168

Query: 120  VEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESE 179
             EE    E+Q E    +  E E     ES+  E    E E +  L     VE P ++E  
Sbjct: 2169 AEE----EAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPEL---EGVEAPEAEEEA 2221

Query: 180  MEEPLSQESQVEEPPSQ-ESEME 201
              EP   E+   E  +Q ESE E
Sbjct: 2222 QPEPEGVETPEAEGEAQPESEGE 2244



 Score = 41.6 bits (96), Expect = 5e-04
 Identities = 43/133 (32%), Positives = 65/133 (48%), Gaps = 12/133 (9%)

Query: 78   DQPSQELPQHELPPEEPVSEGTQHDPLSQEA-ELEEPLSQESEVEEPLSQESQVEEPLSQ 136
            +Q ++   Q E+  EE   EGT+ + L +EA +LEE  ++E   EE +    Q+EE  ++
Sbjct: 1290 EQLAENTVQEEVQLEE-TKEGTEGEGLQEEAVQLEETKTEEGLQEEGV----QLEE--TK 1342

Query: 137  ESEVEEPLSQESQVE--EPLSQESEVEEPLSQESQVEEPLS--QESEMEEPLSQESQVEE 192
            E+E E    +E+Q+E  E    E   EE +  E   E P    Q   +EE L +E   EE
Sbjct: 1343 ETEGEGQQEEEAQLEEIEETGGEGLQEEGVQLEEVKEGPEGGLQGEALEEGLKEEGLPEE 1402

Query: 193  PPSQESEMEELPS 205
                  E+ E  S
Sbjct: 1403 GSVHGQELSEASS 1415



 Score = 38.9 bits (89), Expect = 0.003
 Identities = 51/222 (22%), Positives = 95/222 (42%), Gaps = 25/222 (11%)

Query: 10   PPAKATEAGKRKSSSQPSPSDPKKKTTKVAKK---GKAVRRGRRGK----KGAATKMAAV 62
            P ++  E+ + +  +QP   D +    +V  +   G+A       +    +G   +    
Sbjct: 1956 PESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEE 2015

Query: 63   TAPEAESAPAAPGPSDQPSQELPQHELPPE---EPVSEGTQHDPLSQEAELEEPLSQESE 119
              PE++   A P    + +QE+       E   +P S+G +     +EA+  E   QE+E
Sbjct: 2016 AQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAE 2075

Query: 120  VE-EPLSQESQVEEPLSQ---ESE-VEEPLSQ-ESQVEEPLSQESEVEEPLSQESQVEEP 173
             E  P S++   +E   +   ESE VE P ++ E+Q  E +       E   +   +E P
Sbjct: 2076 GEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAP 2135

Query: 174  LSQ---ESEMEEPLSQESQVEEPP------SQESEMEELPSV 206
             ++   + E E   +Q+++ E  P      +QE+E E  P +
Sbjct: 2136 EAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPEL 2177



 Score = 38.9 bits (89), Expect = 0.003
 Identities = 48/206 (23%), Positives = 80/206 (38%), Gaps = 17/206 (8%)

Query: 11   PAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKG-AATKMAAVTAPEAES 69
            P    E  + +  +QP     + +     ++ + V    +  +G A  +   V APEAE 
Sbjct: 2003 PEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEE 2062

Query: 70   --------APAAPGPSDQPSQELPQHELPPE-EPVSEGTQHDPLSQEAELEEPLSQESEV 120
                       A G +   S+++   E   E +P SEG +      EA+  E +      
Sbjct: 2063 EAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETE 2122

Query: 121  EEPLSQESQVEEPLSQ-----ESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLS 175
             E   +   +E P ++     ESE  E    E + + P S+  E +E   +E+Q E    
Sbjct: 2123 GEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQ-PESEGIEAQE-AEEEAQPELEGV 2180

Query: 176  QESEMEEPLSQESQVEEPPSQESEME 201
            +  E E     ES+  E P  E E +
Sbjct: 2181 EAPEAEGEAQPESEGIEAPEAEGEAQ 2206



 Score = 38.1 bits (87), Expect = 0.005
 Identities = 51/200 (25%), Positives = 80/200 (40%), Gaps = 26/200 (13%)

Query: 16   EAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMAAVTAPEAESAPAAPG 75
            +  +R S  Q + S+ ++      ++   +   + G +G   +  AV   E ++      
Sbjct: 1274 DEAERDSEEQRASSNLEQLAENTVQEEVQLEETKEGTEGEGLQEEAVQLEETKT------ 1327

Query: 76   PSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEE--PLSQESEVEEPLSQESQVEEP 133
              ++  QE        +E   EG Q +    EA+LEE      E   EE +  E   E P
Sbjct: 1328 --EEGLQEEGVQLEETKETEGEGQQEE----EAQLEEIEETGGEGLQEEGVQLEEVKEGP 1381

Query: 134  LS--QESEVEEPLSQESQVEEPL---SQESEVEEPLSQESQVEEPLSQE-----SEMEEP 183
                Q   +EE L +E   EE      + SE   P  + SQ ++P+ +E     S   EP
Sbjct: 1382 EGGLQGEALEEGLKEEGLPEEGSVHGQELSEASSPDGKGSQEDDPVQEEEAGRASASAEP 1441

Query: 184  LSQESQVE--EPPSQESEME 201
               E   E  EPPS  SE +
Sbjct: 1442 CPAEGTEEPTEPPSHLSETD 1461



 Score = 33.9 bits (76), Expect = 0.10
 Identities = 45/180 (25%), Positives = 74/180 (41%), Gaps = 19/180 (10%)

Query: 41   KGKAVRRGRRGKKGAATKMAAVTAPEAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQ 100
            +G A+ + R GK   +   A     EAE          +   +   HE   +   + G  
Sbjct: 1764 EGDAMAQEREGKTHNSETSAGSELGEAEQEGEGISERGETGGQGSGHEDNLQGEAAAGGD 1823

Query: 101  HDPLSQEA-------ELEEPLSQESE-VEEPLS----QESQVE-EPLSQESEVE----EP 143
             DP   +        E E     ESE VE P +    QE++ E +P S++ E      E 
Sbjct: 1824 QDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEA 1883

Query: 144  LSQESQVEEPLSQ-ESEVEEPLSQESQVEEPLSQESEMEEPLSQESQVEEPPSQESEMEE 202
              +   VE P ++ E + E   ++  + E+    E+E  E L  E + +EP S+ +E +E
Sbjct: 1884 QPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGE-DEPESEGAEAQE 1942



 Score = 33.5 bits (75), Expect = 0.13
 Identities = 42/187 (22%), Positives = 70/187 (37%), Gaps = 7/187 (3%)

Query: 3    PKPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMAAV 62
            P+      P    EA K +    P      +  ++  +  +A    +   +G   + A  
Sbjct: 2096 PESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEG 2155

Query: 63   TA-PEAESAPAAPGPSDQPSQELPQHELPPEE----PVSEGTQHDPLSQEAELEEPLSQE 117
             A PE+E   A     ++   EL   E P  E    P SEG +      EA+ E    + 
Sbjct: 2156 EAQPESEGIEAQEA-EEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEA 2214

Query: 118  SEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQE-SQVEEPLSQ 176
             E EE    E +  E    E E +     E+Q E+  S +  + +  S+E S+   P+ +
Sbjct: 2215 PEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASESSSPVPE 2274

Query: 177  ESEMEEP 183
            +     P
Sbjct: 2275 DRPTPPP 2281


>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
          Length = 1427

 Score = 53.9 bits (128), Expect = 9e-08
 Identities = 58/172 (33%), Positives = 73/172 (42%), Gaps = 29/172 (16%)

Query: 56   ATKMAAVTAPEAESAPAAPGPSDQPSQELPQHELPPEEPVSEG----TQHDPLSQEAEL- 110
            A+  AAV  PE  ++PAA  P+ +          PPEEP S      T  +P S  A + 
Sbjct: 1001 ASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVP 1060

Query: 111  --EEPLSQESEV---EEPLSQESQV---EEPLSQESEV---EEPLSQESQV---EEPLSQ 156
              EEP S  + V   EEP S  + V   EEP S  + V   EEP S  + V   EEP S 
Sbjct: 1061 TPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASP 1120

Query: 157  ESEV---EEPLSQESQVEEPLSQESEMEEPLSQESQVEEPPSQESEMEELPS 205
             + V   EEP S  + V  P       EEP      V  P    S    +P+
Sbjct: 1121 AAAVPTPEEPASPAAAVPTP-------EEPAFPAPAVPTPEESASAAVAVPT 1165



 Score = 50.8 bits (120), Expect = 8e-07
 Identities = 61/220 (27%), Positives = 85/220 (38%), Gaps = 34/220 (15%)

Query: 3    PKPRASGPPAKATEAGKRKSS---SQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKM 59
            P P     PA A    +  +S   + P+P +P      V    +            A+  
Sbjct: 1086 PTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEP-----------ASPA 1134

Query: 60   AAVTAPE--AESAPAAPGPSDQPSQEL----PQHELPPEEPVSEGTQHDPLSQ-EAELEE 112
            AAV  PE  A  APA P P +  S  +    P+    P   V    +    +   A LEE
Sbjct: 1135 AAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEE 1194

Query: 113  PLSQESEVEEPLSQESQVEEPLSQESEV---EEPLSQESQV---EEPLSQESEV---EEP 163
            P S  + V  P +  + +EE  S  + V   EEP S  + V   EEP S  + V   EEP
Sbjct: 1195 PTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEP 1254

Query: 164  LSQESQVEEPLSQESEMEEPLSQESQVEEPPSQESEMEEL 203
             S  + V  P     E+  P +     EEP S  + +  L
Sbjct: 1255 TSSAAAVLTP----EELSSPAASVPTPEEPASPAAAVSNL 1290



 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 57/170 (33%), Positives = 76/170 (44%), Gaps = 28/170 (16%)

Query: 57   TKMAAVTAPEAESAPAAPGPS-DQPSQELPQHELP-PEEPVSEGTQHDPLSQEAELEEPL 114
            T    V+ PE  ++PAA  P+ ++P+   P   +P PEEP S      P +     EEP 
Sbjct: 989  TAAVRVSTPEEPASPAAAVPTPEEPTS--PAAAVPTPEEPTS------PAAAVPPPEEPT 1040

Query: 115  SQESEV---EEPLSQESQV---EEPLSQESEV---EEPLSQESQV---EEPLSQESEV-- 160
            S  + V   EEP S  + V   EEP S  + V   EEP S  + V   EEP S  + V  
Sbjct: 1041 SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPT 1100

Query: 161  -EEPLSQESQV---EEPLSQESEMEEPLSQESQVEEPPSQESEMEELPSV 206
             EEP S  + V   EEP S  + +  P    S     P+ E      P+V
Sbjct: 1101 PEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAV 1150



 Score = 41.6 bits (96), Expect = 5e-04
 Identities = 45/171 (26%), Positives = 61/171 (35%), Gaps = 31/171 (18%)

Query: 3    PKPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMAAV 62
            P P  S  PA A           P+P++       VA     +           T  A V
Sbjct: 1164 PTPEESASPAAAV----------PTPAESASFAAVVA----TLEEPTSPAASVPTPAAMV 1209

Query: 63   TAPEAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEVEE 122
               E  ++PAA  P+ +    L      PEEP S      P +    LEEP S  + V  
Sbjct: 1210 ATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTS------PAAAVPTLEEPTSSAAAVLT 1263

Query: 123  PLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEP 173
            P     ++  P +     EEP S       P +  S +EEP S  + V  P
Sbjct: 1264 P----EELSSPAASVPTPEEPAS-------PAAAVSNLEEPASPAAAVPTP 1303



 Score = 32.0 bits (71), Expect = 0.38
 Identities = 34/133 (25%), Positives = 52/133 (39%), Gaps = 24/133 (18%)

Query: 4    KPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMAAVT 63
            +P +S       E     ++S P+P +P      V+   +            A+  AAV 
Sbjct: 1253 EPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEP-----------ASPAAAVP 1301

Query: 64   APEAESAPAAPGPSDQPSQELPQHELPPEEP----------VSEGTQHDPLSQEAE--LE 111
             PE  + PAA  P+ +    +P   +PP E           VS  T   P+S+E    LE
Sbjct: 1302 TPEVAAIPAASVPTPE-VPAIPAAAVPPMEEVSPIGVPFLGVSAHTDSVPISEEGTPVLE 1360

Query: 112  EPLSQESEVEEPL 124
            E  S    ++E L
Sbjct: 1361 EASSTGMWIKEDL 1373


>gi|21361639 DIPB protein [Homo sapiens]
          Length = 344

 Score = 53.5 bits (127), Expect = 1e-07
 Identities = 32/95 (33%), Positives = 45/95 (47%)

Query: 109 ELEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQES 168
           E E  + QE E+E    +ES+ EE    E E E     E + +E   ++SE E    QES
Sbjct: 80  EAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQES 139

Query: 169 QVEEPLSQESEMEEPLSQESQVEEPPSQESEMEEL 203
           + EE   +E E E     E++ E  P  E E E +
Sbjct: 140 EAEEDNQEEGESEAEGETEAESEFDPEIEMEAERV 174



 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 29/90 (32%), Positives = 43/90 (47%)

Query: 117 ESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQ 176
           + E E  + QE ++E    +ESE EE    E + E     E E +E   ++S+ E    Q
Sbjct: 78  KEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQ 137

Query: 177 ESEMEEPLSQESQVEEPPSQESEMEELPSV 206
           ESE EE   +E + E     E+E E  P +
Sbjct: 138 ESEAEEDNQEEGESEAEGETEAESEFDPEI 167



 Score = 37.0 bits (84), Expect = 0.012
 Identities = 30/109 (27%), Positives = 48/109 (44%), Gaps = 13/109 (11%)

Query: 51  GKKGAATKMAAVTAPEAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAEL 110
           GK+ A  K+      E+E+   +    +  S+E  + E   E+   E ++ D    E E+
Sbjct: 77  GKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEED---SEEEM 133

Query: 111 EEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESE 159
           E+   QESE EE   +E         ESE E     ES+ +  +  E+E
Sbjct: 134 ED--EQESEAEEDNQEEG--------ESEAEGETEAESEFDPEIEMEAE 172



 Score = 34.7 bits (78), Expect = 0.059
 Identities = 28/85 (32%), Positives = 38/85 (44%), Gaps = 12/85 (14%)

Query: 96  SEGTQHDPLSQEAELEEPLSQESEVEEPLSQESQVEE-PLSQESEVEEPLSQESQVEEPL 154
           SE  +     +E+E EE    ES+ E   S+E   EE    QESE EE   +E       
Sbjct: 99  SESEEESESEEESETEEESEDESDEE---SEEDSEEEMEDEQESEAEEDNQEEG------ 149

Query: 155 SQESEVEEPLSQESQVEEPLSQESE 179
             ESE E     ES+ +  +  E+E
Sbjct: 150 --ESEAEGETEAESEFDPEIEMEAE 172


>gi|217330641 IWS1 homolog [Homo sapiens]
          Length = 819

 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 52/206 (25%), Positives = 96/206 (46%), Gaps = 31/206 (15%)

Query: 27  SPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMAAVTAPEAESAPAAPG-PSDQPSQELP 85
           S S+ +++    A   +     + G    + +   +   ++E+     G  SD  ++++ 
Sbjct: 93  SDSESEERAEPPASDSENEDVNQHGSDSESEETRKLPGSDSENEELLNGHASDSENEDVG 152

Query: 86  QHELPPEEPVSEGTQHDPLSQEAELEEPLS---QESEVEEP---LSQESQVEEPL----- 134
           +H  P  +   E  Q  P S ++E E+ L     +SE EEP    + +S+ EEP      
Sbjct: 153 KH--PASDSEIEELQKSPAS-DSETEDALKPQISDSESEEPPRHQASDSENEEPPKPRMS 209

Query: 135 -SQESEVEEPLSQESQVEEPL------SQESEVEEPLSQESQVEEPL------SQESEME 181
            S+  E+ +P   +S+ EEP       S+  E+ +P   +S+ E+P       S+  E+ 
Sbjct: 210 DSESEELPKPQVSDSESEEPPRHQASDSENEELPKPRISDSESEDPPRHQASDSENEELP 269

Query: 182 EPLSQESQVEEPP---SQESEMEELP 204
           +P   +S+ E+PP   + +SE EELP
Sbjct: 270 KPRISDSESEDPPRNQASDSENEELP 295



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 40/198 (20%), Positives = 77/198 (38%), Gaps = 6/198 (3%)

Query: 5   PRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMAAVTA 64
           PR     ++  E  K + S   S   PK + +  ++  +  R      +        ++ 
Sbjct: 191 PRHQASDSENEEPPKPRMSDSESEELPKPQVSD-SESEEPPRHQASDSENEELPKPRISD 249

Query: 65  PEAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEVEEPL 124
            E+E  P     SD  ++ELP+  +   E           S+  EL +P   +SE E P 
Sbjct: 250 SESEDPPRHQA-SDSENEELPKPRISDSESEDPPRNQASDSENEELPKPRVSDSESEGPQ 308

Query: 125 SQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVE-EPLSQESQVEEPLSQESEMEEP 183
              +   E        ++P S +    E   +++E++ +    +S ++      S+ EE 
Sbjct: 309 KGPASDSETEDASRHKQKPESDDDSDRENKGEDTEMQNDSFHSDSHMDRKKFHSSDSEE- 367

Query: 184 LSQESQVEEPPSQESEME 201
             +E + ++  S E E E
Sbjct: 368 --EEHKKQKMDSDEDEKE 383


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 52.8 bits (125), Expect = 2e-07
 Identities = 45/195 (23%), Positives = 87/195 (44%), Gaps = 9/195 (4%)

Query: 3   PKPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMAAV 62
           P  +   P + +++  ++  S  P    P +  T+  +   A    +R      TK A +
Sbjct: 229 PLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADI 288

Query: 63  TAPEAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEVEE 122
              E+   P+ P PS  P Q+    + P ++P  E +Q  P        +P +Q S + +
Sbjct: 289 VRGESVK-PSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPA-------KPPAQPSGLTK 340

Query: 123 PLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEE 182
           PL+Q+    +P  Q     +P +Q     +P +Q++  E+P S E    + L+Q   + +
Sbjct: 341 PLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKP-SSEQPGPKALAQPPGVGK 399

Query: 183 PLSQESQVEEPPSQE 197
             +Q+    +PP+Q+
Sbjct: 400 TPAQQPGPAKPPTQQ 414



 Score = 51.6 bits (122), Expect = 5e-07
 Identities = 47/193 (24%), Positives = 81/193 (41%), Gaps = 13/193 (6%)

Query: 10  PPAKATEAGKRKSSSQPSPS----DPKKKTTKVAKKGKAVRRGRRGKKGAATKMAAVTAP 65
           PPA+ T   ++ SS QP P      P    T   + G A    +   +   T       P
Sbjct: 371 PPAQQT-GSEKPSSEQPGPKALAQPPGVGKTPAQQPGPA----KPPTQQVGTPKPLAQQP 425

Query: 66  EAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEVEEPLS 125
             +S   APGP+  P Q+    ++P ++     T     +Q+    +P SQ     +P  
Sbjct: 426 GLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTS----AQQTGPTKPPSQLPGPAKPPP 481

Query: 126 QESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPLS 185
           Q+    +P  Q+    +P SQ+    +P  Q+    +P  Q+    +P SQ+    +P +
Sbjct: 482 QQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSA 541

Query: 186 QESQVEEPPSQES 198
           Q+    +P +Q+S
Sbjct: 542 QQPSPAKPSAQQS 554



 Score = 50.1 bits (118), Expect = 1e-06
 Identities = 51/208 (24%), Positives = 88/208 (42%), Gaps = 20/208 (9%)

Query: 3   PKPRASGPPAKATEAGKRKS-SSQPSPSDPKKK---TTKVAKKGKAVRRGRRGKKGAAT- 57
           P     GP A A   G  K+ + QP P+ P  +   T K   +   ++   +      T 
Sbjct: 381 PSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTP 440

Query: 58  -------KMAAVTAPEAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAEL 110
                  K+ A  A   +++    GP+  PSQ     + PP++P   G    P  Q    
Sbjct: 441 VQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQP---GPAKPPPQQPGSA 497

Query: 111 EEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQV 170
           + P SQ+    +P  Q+    +P  Q+    +P SQ+    +P +Q+    +P +Q+S  
Sbjct: 498 KPP-SQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQST- 555

Query: 171 EEPLSQESEME--EPLSQESQVEEPPSQ 196
            +P+SQ    +  +P +     ++PPSQ
Sbjct: 556 -KPVSQTGSGKPLQPPTVSPSAKQPPSQ 582



 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 52/217 (23%), Positives = 85/217 (39%), Gaps = 20/217 (9%)

Query: 2   SPKPRASGPPAKATEAGKRKSSSQPSPSDPKKKT------TKVAKKGKAVRRGRRGKKGA 55
           SP+P+    P   T A   KSS QP  + PKK        +K  +  K     ++     
Sbjct: 656 SPQPKLKTAPVTTTSAVS-KSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHG 714

Query: 56  ATKMAAVTAPEAESAPAAPGPSDQPSQELPQHELP-----PEEPVSEGTQHDPLSQEAEL 110
           +    A   PEA+S  + P P  +PS    Q + P     P++P       D +S  +  
Sbjct: 715 SPSAKAKQPPEADSL-SKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSAT 773

Query: 111 EEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLS--QESEVEEPLSQES 168
            +P    S+V+     E +   PL  +S   +P        E +S      +  P S   
Sbjct: 774 TKPDIPSSKVQS--QAEEKTTPPLKTDS--AKPSQSFPPTGEKVSPFDSKAIPRPASDSK 829

Query: 169 QVEEP-LSQESEMEEPLSQESQVEEPPSQESEMEELP 204
            +  P  S ES+ ++ +    + EEP   +++M   P
Sbjct: 830 IISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKP 866



 Score = 39.3 bits (90), Expect = 0.002
 Identities = 42/203 (20%), Positives = 81/203 (39%), Gaps = 31/203 (15%)

Query: 29  SDPKKKTTKVAKKGKAVRRGRRGKKGAATKMAAVTAPEAESAPAAPGPSDQPSQE----- 83
           SD +    +  KK K V++  +GK     K      P  +  P   GP   P Q+     
Sbjct: 180 SDSEASQEETTKKQKVVQK-EQGKPEGIIKPPLQQQPP-KPIPKQQGPGRDPLQQDGTPK 237

Query: 84  ---LPQHELPPEEPVSEG-----------TQHDPLSQEAELEEPLSQESEVEE------- 122
                Q E    +P   G           T H  L  + +   P ++++++         
Sbjct: 238 SISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPS 297

Query: 123 -PLSQESQVEEPLSQESEVEEPLSQESQV--EEPLSQESEVEEPLSQESQVEEPLSQESE 179
            P   +  +++P   +   ++P  ++SQ    +P +Q S + +PL+Q+    +P  Q   
Sbjct: 298 LPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPG 357

Query: 180 MEEPLSQESQVEEPPSQESEMEE 202
             +P +Q     +PP+Q++  E+
Sbjct: 358 TTKPPAQPLGPAKPPAQQTGSEK 380



 Score = 33.5 bits (75), Expect = 0.13
 Identities = 27/117 (23%), Positives = 46/117 (39%), Gaps = 2/117 (1%)

Query: 83   ELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEVEEPLSQESQVEEPLSQESEVEE 142
            E+P      E+ + +G + D  SQE+    P          LS        L+ E   ++
Sbjct: 1376 EIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKK 1435

Query: 143  PLSQESQVEEPLSQE--SEVEEPLSQESQVEEPLSQESEMEEPLSQESQVEEPPSQE 197
                E   E+P  QE    + E L      EE    + E ++   ++SQ + P S++
Sbjct: 1436 TQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKD 1492



 Score = 31.6 bits (70), Expect = 0.50
 Identities = 27/121 (22%), Positives = 53/121 (43%), Gaps = 12/121 (9%)

Query: 74   PGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEVEEPLSQESQVEEP 133
            P PS   +  +P        P    +Q   +  + +L +   QE + E       +V+E 
Sbjct: 1127 PAPSGPKASPMPV-------PTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKET 1179

Query: 134  LSQES----EVEEPLSQESQVEEPLSQESEVEEPLSQESQ-VEEPLSQESEMEEPLSQES 188
            LS E        +   +ES++E+  +   + ++PL +E + + E     SE ++PL +E 
Sbjct: 1180 LSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEK 1239

Query: 189  Q 189
            +
Sbjct: 1240 K 1240



 Score = 29.6 bits (65), Expect = 1.9
 Identities = 29/151 (19%), Positives = 67/151 (44%), Gaps = 8/151 (5%)

Query: 59   MAAVTAPEAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQES 118
            M ++TA   +S P     S     E+    +  E  +    + D   Q+ +LE  L +  
Sbjct: 3170 MESLTAETIDSVPTLTTAS-----EVFPEVVGDESALLIVPEEDKQQQQLDLERELLELE 3224

Query: 119  EVEEP-LSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQE 177
            ++++   ++E + E    Q    +E +  + ++EE  S +  +     +E Q +  + QE
Sbjct: 3225 KIKQQRFAEELEWERQEIQRFREQEKIMVQKKLEELQSMKQHLLFQQEEERQAQFMMRQE 3284

Query: 178  --SEMEEPLSQESQVEEPPSQESEMEELPSV 206
              ++ +  L Q  Q+++   Q+ E +++  +
Sbjct: 3285 TLAQQQLQLEQIQQLQQQLHQQLEEQKIRQI 3315



 Score = 28.5 bits (62), Expect = 4.2
 Identities = 46/213 (21%), Positives = 84/213 (39%), Gaps = 21/213 (9%)

Query: 3    PKPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMAAV 62
            P+P  +  P +  E GK K+  +   SD    +++  K  + +        G ++ +  +
Sbjct: 1321 PQPPCTAKPDQV-EPGKEKTEKEDDKSDTS--SSQQPKSPQGLSDTGYSSDGISSSLGEI 1377

Query: 63   TA--PEAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEA-----ELEEPLS 115
             +  P  E         D  SQE      P +    E T    L  +A     E  E  +
Sbjct: 1378 PSLIPTDEKDILKGLKKDSFSQESSPSS-PSDLAKLESTVLSILEAQASTLADEKSEKKT 1436

Query: 116  QESEV--EEPLSQESQVEEPLSQESEVEEPLSQESQVE--EPLSQESEVEEPLSQESQVE 171
            Q  EV  E+P  QE       + E  + E   +ESQ E  +   ++S+ + P S++ +  
Sbjct: 1437 QPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHK-- 1494

Query: 172  EPLSQESEMEEPLSQESQVEEPPSQESEMEELP 204
                ++SE  + ++   +  +   + SE E  P
Sbjct: 1495 ----EKSEFVDDITTRREPYDSVEESSESENSP 1523


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 52.8 bits (125), Expect = 2e-07
 Identities = 45/195 (23%), Positives = 87/195 (44%), Gaps = 9/195 (4%)

Query: 3   PKPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMAAV 62
           P  +   P + +++  ++  S  P    P +  T+  +   A    +R      TK A +
Sbjct: 229 PLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADI 288

Query: 63  TAPEAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEVEE 122
              E+   P+ P PS  P Q+    + P ++P  E +Q  P        +P +Q S + +
Sbjct: 289 VRGESVK-PSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPA-------KPPAQPSGLTK 340

Query: 123 PLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEE 182
           PL+Q+    +P  Q     +P +Q     +P +Q++  E+P S E    + L+Q   + +
Sbjct: 341 PLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKP-SSEQPGPKALAQPPGVGK 399

Query: 183 PLSQESQVEEPPSQE 197
             +Q+    +PP+Q+
Sbjct: 400 TPAQQPGPAKPPTQQ 414



 Score = 51.6 bits (122), Expect = 5e-07
 Identities = 47/193 (24%), Positives = 81/193 (41%), Gaps = 13/193 (6%)

Query: 10  PPAKATEAGKRKSSSQPSPS----DPKKKTTKVAKKGKAVRRGRRGKKGAATKMAAVTAP 65
           PPA+ T   ++ SS QP P      P    T   + G A    +   +   T       P
Sbjct: 371 PPAQQT-GSEKPSSEQPGPKALAQPPGVGKTPAQQPGPA----KPPTQQVGTPKPLAQQP 425

Query: 66  EAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEVEEPLS 125
             +S   APGP+  P Q+    ++P ++     T     +Q+    +P SQ     +P  
Sbjct: 426 GLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTS----AQQTGPTKPPSQLPGPAKPPP 481

Query: 126 QESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPLS 185
           Q+    +P  Q+    +P SQ+    +P  Q+    +P  Q+    +P SQ+    +P +
Sbjct: 482 QQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSA 541

Query: 186 QESQVEEPPSQES 198
           Q+    +P +Q+S
Sbjct: 542 QQPSPAKPSAQQS 554



 Score = 50.1 bits (118), Expect = 1e-06
 Identities = 51/208 (24%), Positives = 88/208 (42%), Gaps = 20/208 (9%)

Query: 3   PKPRASGPPAKATEAGKRKS-SSQPSPSDPKKK---TTKVAKKGKAVRRGRRGKKGAAT- 57
           P     GP A A   G  K+ + QP P+ P  +   T K   +   ++   +      T 
Sbjct: 381 PSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTP 440

Query: 58  -------KMAAVTAPEAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAEL 110
                  K+ A  A   +++    GP+  PSQ     + PP++P   G    P  Q    
Sbjct: 441 VQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQP---GPAKPPPQQPGSA 497

Query: 111 EEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQV 170
           + P SQ+    +P  Q+    +P  Q+    +P SQ+    +P +Q+    +P +Q+S  
Sbjct: 498 KPP-SQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQST- 555

Query: 171 EEPLSQESEME--EPLSQESQVEEPPSQ 196
            +P+SQ    +  +P +     ++PPSQ
Sbjct: 556 -KPVSQTGSGKPLQPPTVSPSAKQPPSQ 582



 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 52/217 (23%), Positives = 85/217 (39%), Gaps = 20/217 (9%)

Query: 2   SPKPRASGPPAKATEAGKRKSSSQPSPSDPKKKT------TKVAKKGKAVRRGRRGKKGA 55
           SP+P+    P   T A   KSS QP  + PKK        +K  +  K     ++     
Sbjct: 656 SPQPKLKTAPVTTTSAVS-KSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHG 714

Query: 56  ATKMAAVTAPEAESAPAAPGPSDQPSQELPQHELP-----PEEPVSEGTQHDPLSQEAEL 110
           +    A   PEA+S  + P P  +PS    Q + P     P++P       D +S  +  
Sbjct: 715 SPSAKAKQPPEADSL-SKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSAT 773

Query: 111 EEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLS--QESEVEEPLSQES 168
            +P    S+V+     E +   PL  +S   +P        E +S      +  P S   
Sbjct: 774 TKPDIPSSKVQS--QAEEKTTPPLKTDS--AKPSQSFPPTGEKVSPFDSKAIPRPASDSK 829

Query: 169 QVEEP-LSQESEMEEPLSQESQVEEPPSQESEMEELP 204
            +  P  S ES+ ++ +    + EEP   +++M   P
Sbjct: 830 IISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKP 866



 Score = 39.3 bits (90), Expect = 0.002
 Identities = 42/203 (20%), Positives = 81/203 (39%), Gaps = 31/203 (15%)

Query: 29  SDPKKKTTKVAKKGKAVRRGRRGKKGAATKMAAVTAPEAESAPAAPGPSDQPSQE----- 83
           SD +    +  KK K V++  +GK     K      P  +  P   GP   P Q+     
Sbjct: 180 SDSEASQEETTKKQKVVQK-EQGKPEGIIKPPLQQQPP-KPIPKQQGPGRDPLQQDGTPK 237

Query: 84  ---LPQHELPPEEPVSEG-----------TQHDPLSQEAELEEPLSQESEVEE------- 122
                Q E    +P   G           T H  L  + +   P ++++++         
Sbjct: 238 SISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPS 297

Query: 123 -PLSQESQVEEPLSQESEVEEPLSQESQV--EEPLSQESEVEEPLSQESQVEEPLSQESE 179
            P   +  +++P   +   ++P  ++SQ    +P +Q S + +PL+Q+    +P  Q   
Sbjct: 298 LPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPG 357

Query: 180 MEEPLSQESQVEEPPSQESEMEE 202
             +P +Q     +PP+Q++  E+
Sbjct: 358 TTKPPAQPLGPAKPPAQQTGSEK 380



 Score = 33.5 bits (75), Expect = 0.13
 Identities = 27/117 (23%), Positives = 46/117 (39%), Gaps = 2/117 (1%)

Query: 83   ELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEVEEPLSQESQVEEPLSQESEVEE 142
            E+P      E+ + +G + D  SQE+    P          LS        L+ E   ++
Sbjct: 1376 EIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKK 1435

Query: 143  PLSQESQVEEPLSQE--SEVEEPLSQESQVEEPLSQESEMEEPLSQESQVEEPPSQE 197
                E   E+P  QE    + E L      EE    + E ++   ++SQ + P S++
Sbjct: 1436 TQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKD 1492



 Score = 31.6 bits (70), Expect = 0.50
 Identities = 27/121 (22%), Positives = 53/121 (43%), Gaps = 12/121 (9%)

Query: 74   PGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEVEEPLSQESQVEEP 133
            P PS   +  +P        P    +Q   +  + +L +   QE + E       +V+E 
Sbjct: 1127 PAPSGPKASPMPV-------PTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKET 1179

Query: 134  LSQES----EVEEPLSQESQVEEPLSQESEVEEPLSQESQ-VEEPLSQESEMEEPLSQES 188
            LS E        +   +ES++E+  +   + ++PL +E + + E     SE ++PL +E 
Sbjct: 1180 LSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEK 1239

Query: 189  Q 189
            +
Sbjct: 1240 K 1240



 Score = 29.6 bits (65), Expect = 1.9
 Identities = 29/151 (19%), Positives = 67/151 (44%), Gaps = 8/151 (5%)

Query: 59   MAAVTAPEAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQES 118
            M ++TA   +S P     S     E+    +  E  +    + D   Q+ +LE  L +  
Sbjct: 3170 MESLTAETIDSVPTLTTAS-----EVFPEVVGDESALLIVPEEDKQQQQLDLERELLELE 3224

Query: 119  EVEEP-LSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQE 177
            ++++   ++E + E    Q    +E +  + ++EE  S +  +     +E Q +  + QE
Sbjct: 3225 KIKQQRFAEELEWERQEIQRFREQEKIMVQKKLEELQSMKQHLLFQQEEERQAQFMMRQE 3284

Query: 178  --SEMEEPLSQESQVEEPPSQESEMEELPSV 206
              ++ +  L Q  Q+++   Q+ E +++  +
Sbjct: 3285 TLAQQQLQLEQIQQLQQQLHQQLEEQKIRQI 3315



 Score = 28.5 bits (62), Expect = 4.2
 Identities = 46/213 (21%), Positives = 84/213 (39%), Gaps = 21/213 (9%)

Query: 3    PKPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMAAV 62
            P+P  +  P +  E GK K+  +   SD    +++  K  + +        G ++ +  +
Sbjct: 1321 PQPPCTAKPDQV-EPGKEKTEKEDDKSDTS--SSQQPKSPQGLSDTGYSSDGISSSLGEI 1377

Query: 63   TA--PEAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEA-----ELEEPLS 115
             +  P  E         D  SQE      P +    E T    L  +A     E  E  +
Sbjct: 1378 PSLIPTDEKDILKGLKKDSFSQESSPSS-PSDLAKLESTVLSILEAQASTLADEKSEKKT 1436

Query: 116  QESEV--EEPLSQESQVEEPLSQESEVEEPLSQESQVE--EPLSQESEVEEPLSQESQVE 171
            Q  EV  E+P  QE       + E  + E   +ESQ E  +   ++S+ + P S++ +  
Sbjct: 1437 QPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHK-- 1494

Query: 172  EPLSQESEMEEPLSQESQVEEPPSQESEMEELP 204
                ++SE  + ++   +  +   + SE E  P
Sbjct: 1495 ----EKSEFVDDITTRREPYDSVEESSESENSP 1523


>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
           [Homo sapiens]
          Length = 916

 Score = 52.4 bits (124), Expect = 3e-07
 Identities = 42/150 (28%), Positives = 68/150 (45%), Gaps = 3/150 (2%)

Query: 55  AATKMAAVTAPEAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPL 114
           A T+  AV+  E E   AA    ++P  E  + E+  ++   + T  +   +E E EE  
Sbjct: 475 AITEELAVSMKE-EKKEAAEEKEEEPEAE--EEEVAAKKSPVKATAPEVKEEEGEKEEEE 531

Query: 115 SQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPL 174
            QE E EE    +S   E    E E      +  Q E     E+E EE  ++E +  E  
Sbjct: 532 GQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEK 591

Query: 175 SQESEMEEPLSQESQVEEPPSQESEMEELP 204
           S+E   +E L  +++VE+P   +S + + P
Sbjct: 592 SEEVATKEELVADAKVEKPEKAKSPVPKSP 621



 Score = 48.5 bits (114), Expect = 4e-06
 Identities = 47/205 (22%), Positives = 84/205 (40%), Gaps = 15/205 (7%)

Query: 4   KPRASGPPAKA----TEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKM 59
           KP+   P  K      E    ++  +   S+ ++  T + ++  AV      K+ A  K 
Sbjct: 438 KPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEE-LAVSMKEEKKEAAEEKE 496

Query: 60  AAVTAPEAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESE 119
                PEAE    A       +++ P     PE    EG + +   QE E EE    +S+
Sbjct: 497 EE---PEAEEEEVA-------AKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSD 546

Query: 120 VEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESE 179
             E    E +      +  + E     E++ EE  ++E +  E  S+E   +E L  +++
Sbjct: 547 QAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAK 606

Query: 180 MEEPLSQESQVEEPPSQESEMEELP 204
           +E+P   +S V + P +E     +P
Sbjct: 607 VEKPEKAKSPVPKSPVEEKGKSPVP 631



 Score = 46.6 bits (109), Expect = 1e-05
 Identities = 45/197 (22%), Positives = 87/197 (44%), Gaps = 21/197 (10%)

Query: 12  AKATEAGKRKSSSQPSPSDPKKKT----TKVAKKGKAVRRGRRGKKGAATKMAAVTAPEA 67
           AK  +  K KS    SP + K K+    + V +KGK+              +      E 
Sbjct: 605 AKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKS-------------PVPKSPVEEK 651

Query: 68  ESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQ-EAELEEPLSQESEVEEPLSQ 126
             +P    P ++  +  P  + P EE         P+ + +++ E    ++ E EE   +
Sbjct: 652 GKSPVPKSPVEEKGKS-PVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVK 710

Query: 127 ESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEME-EPLS 185
           E+  EE + ++ E  + + ++ + E P+ +E+ V E ++    V+  L +E++ E +PL 
Sbjct: 711 EAPKEEKVEKKEEKPKDVPEKKKAESPVKEEA-VAEVVTITKSVKVHLEKETKEEGKPLQ 769

Query: 186 QESQVEEPPSQESEMEE 202
           QE + E+   +    EE
Sbjct: 770 QEKEKEKAGGEGGSEEE 786



 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 43/188 (22%), Positives = 84/188 (44%), Gaps = 28/188 (14%)

Query: 19  KRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMAAVTAPEAESAPAAPGPSD 78
           ++K +++    +P+ +  +VA K   V+                TAPE +          
Sbjct: 487 EKKEAAEEKEEEPEAEEEEVAAKKSPVK---------------ATAPEVKE------EEG 525

Query: 79  QPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEVEEPLSQ---ESQVEEPLS 135
           +  +E  Q E   EE   EG + D   +    +E  S++ E E+   +   E++ EE  +
Sbjct: 526 EKEEEEGQEE---EEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEA 582

Query: 136 QESEVEEPLSQESQVEEPLSQESEVEEPLSQESQV-EEPLSQESEMEEPLSQESQVEEPP 194
           +E +  E  S+E   +E L  +++VE+P   +S V + P+ ++ +   P S   +  + P
Sbjct: 583 KEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSP 642

Query: 195 SQESEMEE 202
             +S +EE
Sbjct: 643 VPKSPVEE 650


>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
           [Homo sapiens]
          Length = 540

 Score = 52.4 bits (124), Expect = 3e-07
 Identities = 42/150 (28%), Positives = 68/150 (45%), Gaps = 3/150 (2%)

Query: 55  AATKMAAVTAPEAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPL 114
           A T+  AV+  E E   AA    ++P  E  + E+  ++   + T  +   +E E EE  
Sbjct: 99  AITEELAVSMKE-EKKEAAEEKEEEPEAE--EEEVAAKKSPVKATAPEVKEEEGEKEEEE 155

Query: 115 SQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPL 174
            QE E EE    +S   E    E E      +  Q E     E+E EE  ++E +  E  
Sbjct: 156 GQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEK 215

Query: 175 SQESEMEEPLSQESQVEEPPSQESEMEELP 204
           S+E   +E L  +++VE+P   +S + + P
Sbjct: 216 SEEVATKEELVADAKVEKPEKAKSPVPKSP 245



 Score = 48.5 bits (114), Expect = 4e-06
 Identities = 47/205 (22%), Positives = 84/205 (40%), Gaps = 15/205 (7%)

Query: 4   KPRASGPPAKA----TEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKM 59
           KP+   P  K      E    ++  +   S+ ++  T + ++  AV      K+ A  K 
Sbjct: 62  KPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEE-LAVSMKEEKKEAAEEKE 120

Query: 60  AAVTAPEAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESE 119
                PEAE    A       +++ P     PE    EG + +   QE E EE    +S+
Sbjct: 121 EE---PEAEEEEVA-------AKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSD 170

Query: 120 VEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESE 179
             E    E +      +  + E     E++ EE  ++E +  E  S+E   +E L  +++
Sbjct: 171 QAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAK 230

Query: 180 MEEPLSQESQVEEPPSQESEMEELP 204
           +E+P   +S V + P +E     +P
Sbjct: 231 VEKPEKAKSPVPKSPVEEKGKSPVP 255



 Score = 46.6 bits (109), Expect = 1e-05
 Identities = 45/197 (22%), Positives = 87/197 (44%), Gaps = 21/197 (10%)

Query: 12  AKATEAGKRKSSSQPSPSDPKKKT----TKVAKKGKAVRRGRRGKKGAATKMAAVTAPEA 67
           AK  +  K KS    SP + K K+    + V +KGK+              +      E 
Sbjct: 229 AKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKS-------------PVPKSPVEEK 275

Query: 68  ESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQ-EAELEEPLSQESEVEEPLSQ 126
             +P    P ++  +  P  + P EE         P+ + +++ E    ++ E EE   +
Sbjct: 276 GKSPVPKSPVEEKGKS-PVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVK 334

Query: 127 ESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEME-EPLS 185
           E+  EE + ++ E  + + ++ + E P+ +E+ V E ++    V+  L +E++ E +PL 
Sbjct: 335 EAPKEEKVEKKEEKPKDVPEKKKAESPVKEEA-VAEVVTITKSVKVHLEKETKEEGKPLQ 393

Query: 186 QESQVEEPPSQESEMEE 202
           QE + E+   +    EE
Sbjct: 394 QEKEKEKAGGEGGSEEE 410



 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 43/188 (22%), Positives = 84/188 (44%), Gaps = 28/188 (14%)

Query: 19  KRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMAAVTAPEAESAPAAPGPSD 78
           ++K +++    +P+ +  +VA K   V+                TAPE +          
Sbjct: 111 EKKEAAEEKEEEPEAEEEEVAAKKSPVK---------------ATAPEVKE------EEG 149

Query: 79  QPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEVEEPLSQ---ESQVEEPLS 135
           +  +E  Q E   EE   EG + D   +    +E  S++ E E+   +   E++ EE  +
Sbjct: 150 EKEEEEGQEE---EEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEA 206

Query: 136 QESEVEEPLSQESQVEEPLSQESEVEEPLSQESQV-EEPLSQESEMEEPLSQESQVEEPP 194
           +E +  E  S+E   +E L  +++VE+P   +S V + P+ ++ +   P S   +  + P
Sbjct: 207 KEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSP 266

Query: 195 SQESEMEE 202
             +S +EE
Sbjct: 267 VPKSPVEE 274


>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 51.6 bits (122), Expect = 5e-07
 Identities = 45/179 (25%), Positives = 74/179 (41%), Gaps = 11/179 (6%)

Query: 20   RKSSSQPSPSDP--KKKTTKVAKKGKAVRRGRRGKKGAATKMAAVTAPEAESAPAAPGPS 77
            + S  +P  S P  KKK     K  K +   +R  +    K++    P +  A       
Sbjct: 1134 KNSPLEPDTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVI---- 1189

Query: 78   DQPSQELPQHELPPEEPVSEGT----QHDPLSQEAELEEPLSQESEVEEPLSQESQVEEP 133
             +P   +P+    P+   SE T    +  PL +E + EE +  E+E  E   +E      
Sbjct: 1190 -EPIVSIPKAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSE 1248

Query: 134  LSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPLSQESQVEE 192
            +   S  +   S E++ +EP  +E E +  +S+E +  E   QE E  EP  +E    E
Sbjct: 1249 VPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAE 1307



 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 45/198 (22%), Positives = 85/198 (42%), Gaps = 17/198 (8%)

Query: 10   PPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMAAVTAPEAES 69
            P  + +E         P P + K++    A+  +A       ++G     A+   P A  
Sbjct: 1202 PKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEA-------EEGEEEDAASSEVPAASP 1254

Query: 70   APAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEVEEPLSQESQ 129
            A ++  P  +  +  P+ E   E+P     Q     ++ ELEEP  +E   EE  + E+ 
Sbjct: 1255 ADSSNSPETETKE--PEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEE---EEDAAAETA 1309

Query: 130  VEEPLSQESEVEEPL--SQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEM---EEPL 184
              +    + E +  L  +++ ++EE  ++E   EEP  QES ++  + +  E    +E  
Sbjct: 1310 QNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEET 1369

Query: 185  SQESQVEEPPSQESEMEE 202
              +S+ E+P    S + E
Sbjct: 1370 ELDSEEEQPSHDTSVVSE 1387



 Score = 45.1 bits (105), Expect = 4e-05
 Identities = 45/164 (27%), Positives = 71/164 (43%), Gaps = 25/164 (15%)

Query: 65   PEAESAPAAPGPSDQPSQ-ELPQHELPPEEPVSE---------GTQHDP---------LS 105
            PE E     P  S++  Q E  Q EL   EP  E            HD           +
Sbjct: 1268 PEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLEST 1327

Query: 106  QEAELEEPLSQESEVEEPLSQESQVEEPLSQESEV---EEPLSQESQVEEPLSQESEVEE 162
            ++ ELEE  ++E   EEP  QES ++  + +  E    +E    +S+ E+P    S V E
Sbjct: 1328 KKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSE 1387

Query: 163  PLSQESQVEEPLSQESEMEEPLSQESQVEEPPSQESEMEELPSV 206
               Q +  E+   ++S  +E L +  + EE P  E ++E + +V
Sbjct: 1388 ---QMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAV 1428



 Score = 35.0 bits (79), Expect = 0.045
 Identities = 27/108 (25%), Positives = 51/108 (47%), Gaps = 6/108 (5%)

Query: 92   EEPVSEGTQHDPLSQEAELEEPLSQESEV---EEPLSQESQVEEPLSQESEVEEPLSQES 148
            E+P  E  + +P  QE+ L+  + +  E    +E    +S+ E+P    S V E   Q +
Sbjct: 1334 EQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSE---QMA 1390

Query: 149  QVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPLSQESQVEEPPSQ 196
              E+   ++S  +E L +  + EE    E ++E   + +S  +E  S+
Sbjct: 1391 GSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSE 1438



 Score = 31.6 bits (70), Expect = 0.50
 Identities = 23/75 (30%), Positives = 40/75 (53%), Gaps = 10/75 (13%)

Query: 118 SEVEEPLSQESQVEEPLSQESEVE----EPLSQESQVEEPLSQESEVEEPLSQESQVEEP 173
           SE EE  ++E + EEP  QE E+E    + +S E++ ++  S ESE      ++ +V  P
Sbjct: 787 SEEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESE------KKPEVMAP 840

Query: 174 LSQESEMEEPLSQES 188
           +S     ++ L  +S
Sbjct: 841 VSSTRLSKQVLPHDS 855



 Score = 29.3 bits (64), Expect = 2.5
 Identities = 21/71 (29%), Positives = 35/71 (49%), Gaps = 10/71 (14%)

Query: 92  EEPVSEGTQHDPLSQEAELE----EPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQE 147
           EE   EG   +P  QE ELE    + +S E++ ++  S ES+      ++ EV  P+S  
Sbjct: 791 EEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESE------KKPEVMAPVSST 844

Query: 148 SQVEEPLSQES 158
              ++ L  +S
Sbjct: 845 RLSKQVLPHDS 855



 Score = 28.5 bits (62), Expect = 4.2
 Identities = 19/86 (22%), Positives = 34/86 (39%), Gaps = 4/86 (4%)

Query: 114  LSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEP 173
            + Q+S V+   +    ++ P  Q   VE P S + Q   P   +     P   +   + P
Sbjct: 1618 MMQQSSVQP--AANCSIKSP--QSCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPP 1673

Query: 174  LSQESEMEEPLSQESQVEEPPSQESE 199
              Q+   ++P  Q  Q   PP  + +
Sbjct: 1674 PPQQQPQQQPQPQPQQPPPPPPPQQQ 1699



 Score = 28.5 bits (62), Expect = 4.2
 Identities = 14/52 (26%), Positives = 21/52 (40%)

Query: 65   PEAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQ 116
            P     P  P P  QP+ + P  +  P++      Q  P     + + PLSQ
Sbjct: 1653 PPPPQQPQPPPPQPQPAPQPPPPQQQPQQQPQPQPQQPPPPPPPQQQPPLSQ 1704


>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 51.6 bits (122), Expect = 5e-07
 Identities = 45/179 (25%), Positives = 74/179 (41%), Gaps = 11/179 (6%)

Query: 20   RKSSSQPSPSDP--KKKTTKVAKKGKAVRRGRRGKKGAATKMAAVTAPEAESAPAAPGPS 77
            + S  +P  S P  KKK     K  K +   +R  +    K++    P +  A       
Sbjct: 1134 KNSPLEPDTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVI---- 1189

Query: 78   DQPSQELPQHELPPEEPVSEGT----QHDPLSQEAELEEPLSQESEVEEPLSQESQVEEP 133
             +P   +P+    P+   SE T    +  PL +E + EE +  E+E  E   +E      
Sbjct: 1190 -EPIVSIPKAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSE 1248

Query: 134  LSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPLSQESQVEE 192
            +   S  +   S E++ +EP  +E E +  +S+E +  E   QE E  EP  +E    E
Sbjct: 1249 VPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAE 1307



 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 45/198 (22%), Positives = 85/198 (42%), Gaps = 17/198 (8%)

Query: 10   PPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMAAVTAPEAES 69
            P  + +E         P P + K++    A+  +A       ++G     A+   P A  
Sbjct: 1202 PKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEA-------EEGEEEDAASSEVPAASP 1254

Query: 70   APAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEVEEPLSQESQ 129
            A ++  P  +  +  P+ E   E+P     Q     ++ ELEEP  +E   EE  + E+ 
Sbjct: 1255 ADSSNSPETETKE--PEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEE---EEDAAAETA 1309

Query: 130  VEEPLSQESEVEEPL--SQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEM---EEPL 184
              +    + E +  L  +++ ++EE  ++E   EEP  QES ++  + +  E    +E  
Sbjct: 1310 QNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEET 1369

Query: 185  SQESQVEEPPSQESEMEE 202
              +S+ E+P    S + E
Sbjct: 1370 ELDSEEEQPSHDTSVVSE 1387



 Score = 45.1 bits (105), Expect = 4e-05
 Identities = 45/164 (27%), Positives = 71/164 (43%), Gaps = 25/164 (15%)

Query: 65   PEAESAPAAPGPSDQPSQ-ELPQHELPPEEPVSE---------GTQHDP---------LS 105
            PE E     P  S++  Q E  Q EL   EP  E            HD           +
Sbjct: 1268 PEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLEST 1327

Query: 106  QEAELEEPLSQESEVEEPLSQESQVEEPLSQESEV---EEPLSQESQVEEPLSQESEVEE 162
            ++ ELEE  ++E   EEP  QES ++  + +  E    +E    +S+ E+P    S V E
Sbjct: 1328 KKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSE 1387

Query: 163  PLSQESQVEEPLSQESEMEEPLSQESQVEEPPSQESEMEELPSV 206
               Q +  E+   ++S  +E L +  + EE P  E ++E + +V
Sbjct: 1388 ---QMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAV 1428



 Score = 35.0 bits (79), Expect = 0.045
 Identities = 27/108 (25%), Positives = 51/108 (47%), Gaps = 6/108 (5%)

Query: 92   EEPVSEGTQHDPLSQEAELEEPLSQESEV---EEPLSQESQVEEPLSQESEVEEPLSQES 148
            E+P  E  + +P  QE+ L+  + +  E    +E    +S+ E+P    S V E   Q +
Sbjct: 1334 EQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSE---QMA 1390

Query: 149  QVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPLSQESQVEEPPSQ 196
              E+   ++S  +E L +  + EE    E ++E   + +S  +E  S+
Sbjct: 1391 GSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSE 1438



 Score = 31.6 bits (70), Expect = 0.50
 Identities = 23/75 (30%), Positives = 40/75 (53%), Gaps = 10/75 (13%)

Query: 118 SEVEEPLSQESQVEEPLSQESEVE----EPLSQESQVEEPLSQESEVEEPLSQESQVEEP 173
           SE EE  ++E + EEP  QE E+E    + +S E++ ++  S ESE      ++ +V  P
Sbjct: 787 SEEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESE------KKPEVMAP 840

Query: 174 LSQESEMEEPLSQES 188
           +S     ++ L  +S
Sbjct: 841 VSSTRLSKQVLPHDS 855



 Score = 29.3 bits (64), Expect = 2.5
 Identities = 21/71 (29%), Positives = 35/71 (49%), Gaps = 10/71 (14%)

Query: 92  EEPVSEGTQHDPLSQEAELE----EPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQE 147
           EE   EG   +P  QE ELE    + +S E++ ++  S ES+      ++ EV  P+S  
Sbjct: 791 EEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESE------KKPEVMAPVSST 844

Query: 148 SQVEEPLSQES 158
              ++ L  +S
Sbjct: 845 RLSKQVLPHDS 855



 Score = 28.5 bits (62), Expect = 4.2
 Identities = 19/86 (22%), Positives = 34/86 (39%), Gaps = 4/86 (4%)

Query: 114  LSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEP 173
            + Q+S V+   +    ++ P  Q   VE P S + Q   P   +     P   +   + P
Sbjct: 1618 MMQQSSVQP--AANCSIKSP--QSCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPP 1673

Query: 174  LSQESEMEEPLSQESQVEEPPSQESE 199
              Q+   ++P  Q  Q   PP  + +
Sbjct: 1674 PPQQQPQQQPQPQPQQPPPPPPPQQQ 1699



 Score = 28.5 bits (62), Expect = 4.2
 Identities = 14/52 (26%), Positives = 21/52 (40%)

Query: 65   PEAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQ 116
            P     P  P P  QP+ + P  +  P++      Q  P     + + PLSQ
Sbjct: 1653 PPPPQQPQPPPPQPQPAPQPPPPQQQPQQQPQPQPQQPPPPPPPQQQPPLSQ 1704


>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 51.6 bits (122), Expect = 5e-07
 Identities = 45/179 (25%), Positives = 74/179 (41%), Gaps = 11/179 (6%)

Query: 20   RKSSSQPSPSDP--KKKTTKVAKKGKAVRRGRRGKKGAATKMAAVTAPEAESAPAAPGPS 77
            + S  +P  S P  KKK     K  K +   +R  +    K++    P +  A       
Sbjct: 1134 KNSPLEPDTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVI---- 1189

Query: 78   DQPSQELPQHELPPEEPVSEGT----QHDPLSQEAELEEPLSQESEVEEPLSQESQVEEP 133
             +P   +P+    P+   SE T    +  PL +E + EE +  E+E  E   +E      
Sbjct: 1190 -EPIVSIPKAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSE 1248

Query: 134  LSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPLSQESQVEE 192
            +   S  +   S E++ +EP  +E E +  +S+E +  E   QE E  EP  +E    E
Sbjct: 1249 VPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAE 1307



 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 45/198 (22%), Positives = 85/198 (42%), Gaps = 17/198 (8%)

Query: 10   PPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMAAVTAPEAES 69
            P  + +E         P P + K++    A+  +A       ++G     A+   P A  
Sbjct: 1202 PKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEA-------EEGEEEDAASSEVPAASP 1254

Query: 70   APAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEVEEPLSQESQ 129
            A ++  P  +  +  P+ E   E+P     Q     ++ ELEEP  +E   EE  + E+ 
Sbjct: 1255 ADSSNSPETETKE--PEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEE---EEDAAAETA 1309

Query: 130  VEEPLSQESEVEEPL--SQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEM---EEPL 184
              +    + E +  L  +++ ++EE  ++E   EEP  QES ++  + +  E    +E  
Sbjct: 1310 QNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEET 1369

Query: 185  SQESQVEEPPSQESEMEE 202
              +S+ E+P    S + E
Sbjct: 1370 ELDSEEEQPSHDTSVVSE 1387



 Score = 45.1 bits (105), Expect = 4e-05
 Identities = 45/164 (27%), Positives = 71/164 (43%), Gaps = 25/164 (15%)

Query: 65   PEAESAPAAPGPSDQPSQ-ELPQHELPPEEPVSE---------GTQHDP---------LS 105
            PE E     P  S++  Q E  Q EL   EP  E            HD           +
Sbjct: 1268 PEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLEST 1327

Query: 106  QEAELEEPLSQESEVEEPLSQESQVEEPLSQESEV---EEPLSQESQVEEPLSQESEVEE 162
            ++ ELEE  ++E   EEP  QES ++  + +  E    +E    +S+ E+P    S V E
Sbjct: 1328 KKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSE 1387

Query: 163  PLSQESQVEEPLSQESEMEEPLSQESQVEEPPSQESEMEELPSV 206
               Q +  E+   ++S  +E L +  + EE P  E ++E + +V
Sbjct: 1388 ---QMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAV 1428



 Score = 35.0 bits (79), Expect = 0.045
 Identities = 27/108 (25%), Positives = 51/108 (47%), Gaps = 6/108 (5%)

Query: 92   EEPVSEGTQHDPLSQEAELEEPLSQESEV---EEPLSQESQVEEPLSQESEVEEPLSQES 148
            E+P  E  + +P  QE+ L+  + +  E    +E    +S+ E+P    S V E   Q +
Sbjct: 1334 EQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSE---QMA 1390

Query: 149  QVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPLSQESQVEEPPSQ 196
              E+   ++S  +E L +  + EE    E ++E   + +S  +E  S+
Sbjct: 1391 GSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSE 1438



 Score = 31.6 bits (70), Expect = 0.50
 Identities = 23/75 (30%), Positives = 40/75 (53%), Gaps = 10/75 (13%)

Query: 118 SEVEEPLSQESQVEEPLSQESEVE----EPLSQESQVEEPLSQESEVEEPLSQESQVEEP 173
           SE EE  ++E + EEP  QE E+E    + +S E++ ++  S ESE      ++ +V  P
Sbjct: 787 SEEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESE------KKPEVMAP 840

Query: 174 LSQESEMEEPLSQES 188
           +S     ++ L  +S
Sbjct: 841 VSSTRLSKQVLPHDS 855



 Score = 29.3 bits (64), Expect = 2.5
 Identities = 21/71 (29%), Positives = 35/71 (49%), Gaps = 10/71 (14%)

Query: 92  EEPVSEGTQHDPLSQEAELE----EPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQE 147
           EE   EG   +P  QE ELE    + +S E++ ++  S ES+      ++ EV  P+S  
Sbjct: 791 EEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESE------KKPEVMAPVSST 844

Query: 148 SQVEEPLSQES 158
              ++ L  +S
Sbjct: 845 RLSKQVLPHDS 855



 Score = 28.5 bits (62), Expect = 4.2
 Identities = 19/86 (22%), Positives = 34/86 (39%), Gaps = 4/86 (4%)

Query: 114  LSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEP 173
            + Q+S V+   +    ++ P  Q   VE P S + Q   P   +     P   +   + P
Sbjct: 1618 MMQQSSVQP--AANCSIKSP--QSCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPP 1673

Query: 174  LSQESEMEEPLSQESQVEEPPSQESE 199
              Q+   ++P  Q  Q   PP  + +
Sbjct: 1674 PPQQQPQQQPQPQPQQPPPPPPPQQQ 1699



 Score = 28.5 bits (62), Expect = 4.2
 Identities = 14/52 (26%), Positives = 21/52 (40%)

Query: 65   PEAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQ 116
            P     P  P P  QP+ + P  +  P++      Q  P     + + PLSQ
Sbjct: 1653 PPPPQQPQPPPPQPQPAPQPPPPQQQPQQQPQPQPQQPPPPPPPQQQPPLSQ 1704


>gi|75677612 leucine rich repeat containing 37, member A3 [Homo
           sapiens]
          Length = 1634

 Score = 51.2 bits (121), Expect = 6e-07
 Identities = 37/130 (28%), Positives = 59/130 (45%), Gaps = 4/130 (3%)

Query: 68  ESAPAAPGPSDQPSQELPQHELPPEEP-VSEGTQHDP--LSQEAELEEPLSQESEVEEPL 124
           + APA P  S   S  LP HE+  + P   +   H P    + A++E  ++ E    E  
Sbjct: 259 QEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEP-TNETE 317

Query: 125 SQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPL 184
           S ++Q E P+    EVE   +Q+    EP     E E  +S++ Q  +P     E+E   
Sbjct: 318 SSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESSREVESSP 377

Query: 185 SQESQVEEPP 194
           +Q+    +PP
Sbjct: 378 TQQETPGQPP 387



 Score = 33.5 bits (75), Expect = 0.13
 Identities = 34/130 (26%), Positives = 50/130 (38%), Gaps = 10/130 (7%)

Query: 87  HELPPEEPVSEGTQHDPLSQEAELEEPLSQESEV--EEPLSQESQVE------EPLSQES 138
           H+L   +   +  Q++  S +      L  E  V  +EP     QV       EP +Q  
Sbjct: 168 HQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNP 227

Query: 139 EVEEPLSQES-QVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPLSQESQVE-EPPSQ 196
           E  E +   S Q E P      +EE  S   Q    L  ES ME       +V  +PP +
Sbjct: 228 ETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGE 287

Query: 197 ESEMEELPSV 206
           +     LP++
Sbjct: 288 DQAYYHLPNI 297



 Score = 32.7 bits (73), Expect = 0.22
 Identities = 32/122 (26%), Positives = 50/122 (40%), Gaps = 6/122 (4%)

Query: 86  QHELPPEEPVSEGTQHDPLS--QEAELEEPLSQESEVEEPLSQESQVEEPLSQESEVEEP 143
           QH  PP  P S   +  PL+  QE   + P    +E   P  QE+  E P + E      
Sbjct: 455 QHGGPPLLPESS-EEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSL 513

Query: 144 LSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPLSQESQVEEPPSQESEMEEL 203
             QE+  + P      V +P  + S + +   Q  ++   ++ ES  E   S    M+E 
Sbjct: 514 THQEAPAQTPEFPNVVVAQP-PEHSHLTQATVQPLDLGFTITPESMTEVELS--PTMKET 570

Query: 204 PS 205
           P+
Sbjct: 571 PT 572



 Score = 29.3 bits (64), Expect = 2.5
 Identities = 40/169 (23%), Positives = 59/169 (34%), Gaps = 14/169 (8%)

Query: 11  PAKATEAGKRKSSS---QPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMAAVTAPEA 67
           P + +E+ +   SS   Q +P  P +              G       A+   +V  P+ 
Sbjct: 363 PVQPSESSREVESSPTQQETPGQPPEHHEVTVSPP-----GHHQTHHLASPSVSVKPPDV 417

Query: 68  ESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEVEE-PLS- 125
           +   AA  PS +    L   E       S      P  Q      PL  ES  E  PL+ 
Sbjct: 418 QLTIAAE-PSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGG--PPLLPESSEEAGPLAV 474

Query: 126 -QESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEP 173
            QE+  + P    +E   P  QE+  E P + E        QE+  + P
Sbjct: 475 QQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTP 523


>gi|239740955 PREDICTED: similar to c114 SLIT-like testicular
           protein isoform 1 [Homo sapiens]
          Length = 1635

 Score = 50.8 bits (120), Expect = 8e-07
 Identities = 37/130 (28%), Positives = 59/130 (45%), Gaps = 4/130 (3%)

Query: 68  ESAPAAPGPSDQPSQELPQHELPPEEP-VSEGTQHDP--LSQEAELEEPLSQESEVEEPL 124
           + APA P  S   S  LP HE+  + P   +   H P    + A++E  ++ E    E  
Sbjct: 259 QEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEP-TNETE 317

Query: 125 SQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPL 184
           S ++Q E P+    EVE   +Q+    EP     E E  +S++ Q  +P     E+E   
Sbjct: 318 SSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREVESSP 377

Query: 185 SQESQVEEPP 194
           +Q+    +PP
Sbjct: 378 TQQETPGQPP 387



 Score = 33.1 bits (74), Expect = 0.17
 Identities = 32/122 (26%), Positives = 51/122 (41%), Gaps = 6/122 (4%)

Query: 86  QHELPPEEPVSEGTQHDPLS--QEAELEEPLSQESEVEEPLSQESQVEEPLSQESEVEEP 143
           QH  PP  P S   +  PL+  QE   + P    +E   P  QE+  E P + E      
Sbjct: 455 QHGGPPLLPESS-EEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSL 513

Query: 144 LSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPLSQESQVEEPPSQESEMEEL 203
             QE+  + P      V +P  + S + +   Q  ++   ++ ES+ E   S    M+E 
Sbjct: 514 THQEAPAQTPEFPNVVVAQP-PEHSHLTQATVQPLDLGFTITPESKTEVELS--PTMKET 570

Query: 204 PS 205
           P+
Sbjct: 571 PT 572



 Score = 30.8 bits (68), Expect = 0.85
 Identities = 23/77 (29%), Positives = 32/77 (41%), Gaps = 2/77 (2%)

Query: 132 EPLSQESEVEEPLSQES-QVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPLSQESQV 190
           EP +Q  E  E +   S Q E P      +EE  S   Q    L  ES ME       +V
Sbjct: 221 EPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEV 280

Query: 191 E-EPPSQESEMEELPSV 206
             +PP ++     LP++
Sbjct: 281 SVQPPGEDQAYYHLPNI 297



 Score = 28.9 bits (63), Expect = 3.2
 Identities = 32/121 (26%), Positives = 45/121 (37%), Gaps = 6/121 (4%)

Query: 56  ATKMAAVTAPEAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLS 115
           A+   +V  P+ +   AA  PS +    L   E       S      P  Q      PL 
Sbjct: 406 ASPSVSVKPPDVQLTIAAE-PSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGG--PPLL 462

Query: 116 QESEVEE-PLS--QESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEE 172
            ES  E  PL+  QE+  + P    +E   P  QE+  E P + E        QE+  + 
Sbjct: 463 PESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQT 522

Query: 173 P 173
           P
Sbjct: 523 P 523


>gi|239740953 PREDICTED: similar to c114 SLIT-like testicular
           protein isoform 2 [Homo sapiens]
          Length = 1700

 Score = 50.8 bits (120), Expect = 8e-07
 Identities = 37/130 (28%), Positives = 59/130 (45%), Gaps = 4/130 (3%)

Query: 68  ESAPAAPGPSDQPSQELPQHELPPEEP-VSEGTQHDP--LSQEAELEEPLSQESEVEEPL 124
           + APA P  S   S  LP HE+  + P   +   H P    + A++E  ++ E    E  
Sbjct: 259 QEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEP-TNETE 317

Query: 125 SQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPL 184
           S ++Q E P+    EVE   +Q+    EP     E E  +S++ Q  +P     E+E   
Sbjct: 318 SSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREVESSP 377

Query: 185 SQESQVEEPP 194
           +Q+    +PP
Sbjct: 378 TQQETPGQPP 387



 Score = 33.1 bits (74), Expect = 0.17
 Identities = 32/122 (26%), Positives = 51/122 (41%), Gaps = 6/122 (4%)

Query: 86  QHELPPEEPVSEGTQHDPLS--QEAELEEPLSQESEVEEPLSQESQVEEPLSQESEVEEP 143
           QH  PP  P S   +  PL+  QE   + P    +E   P  QE+  E P + E      
Sbjct: 455 QHGGPPLLPESS-EEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSL 513

Query: 144 LSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPLSQESQVEEPPSQESEMEEL 203
             QE+  + P      V +P  + S + +   Q  ++   ++ ES+ E   S    M+E 
Sbjct: 514 THQEAPAQTPEFPNVVVAQP-PEHSHLTQATVQPLDLGFTITPESKTEVELS--PTMKET 570

Query: 204 PS 205
           P+
Sbjct: 571 PT 572



 Score = 30.8 bits (68), Expect = 0.85
 Identities = 23/77 (29%), Positives = 32/77 (41%), Gaps = 2/77 (2%)

Query: 132 EPLSQESEVEEPLSQES-QVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPLSQESQV 190
           EP +Q  E  E +   S Q E P      +EE  S   Q    L  ES ME       +V
Sbjct: 221 EPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEV 280

Query: 191 E-EPPSQESEMEELPSV 206
             +PP ++     LP++
Sbjct: 281 SVQPPGEDQAYYHLPNI 297



 Score = 28.9 bits (63), Expect = 3.2
 Identities = 32/121 (26%), Positives = 45/121 (37%), Gaps = 6/121 (4%)

Query: 56  ATKMAAVTAPEAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLS 115
           A+   +V  P+ +   AA  PS +    L   E       S      P  Q      PL 
Sbjct: 406 ASPSVSVKPPDVQLTIAAE-PSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGG--PPLL 462

Query: 116 QESEVEE-PLS--QESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEE 172
            ES  E  PL+  QE+  + P    +E   P  QE+  E P + E        QE+  + 
Sbjct: 463 PESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQT 522

Query: 173 P 173
           P
Sbjct: 523 P 523


>gi|116325993 c114 SLIT-like testicular protein [Homo sapiens]
          Length = 1700

 Score = 50.8 bits (120), Expect = 8e-07
 Identities = 37/130 (28%), Positives = 59/130 (45%), Gaps = 4/130 (3%)

Query: 68  ESAPAAPGPSDQPSQELPQHELPPEEP-VSEGTQHDP--LSQEAELEEPLSQESEVEEPL 124
           + APA P  S   S  LP HE+  + P   +   H P    + A++E  ++ E    E  
Sbjct: 259 QEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEP-TNETE 317

Query: 125 SQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPL 184
           S ++Q E P+    EVE   +Q+    EP     E E  +S++ Q  +P     E+E   
Sbjct: 318 SSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREVESSP 377

Query: 185 SQESQVEEPP 194
           +Q+    +PP
Sbjct: 378 TQQETPGQPP 387



 Score = 33.1 bits (74), Expect = 0.17
 Identities = 32/122 (26%), Positives = 51/122 (41%), Gaps = 6/122 (4%)

Query: 86  QHELPPEEPVSEGTQHDPLS--QEAELEEPLSQESEVEEPLSQESQVEEPLSQESEVEEP 143
           QH  PP  P S   +  PL+  QE   + P    +E   P  QE+  E P + E      
Sbjct: 455 QHGGPPLLPESS-EEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSL 513

Query: 144 LSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPLSQESQVEEPPSQESEMEEL 203
             QE+  + P      V +P  + S + +   Q  ++   ++ ES+ E   S    M+E 
Sbjct: 514 THQEAPAQTPEFPNVVVAQP-PEHSHLTQATVQPLDLGFTITPESKTEVELS--PTMKET 570

Query: 204 PS 205
           P+
Sbjct: 571 PT 572



 Score = 30.8 bits (68), Expect = 0.85
 Identities = 23/77 (29%), Positives = 32/77 (41%), Gaps = 2/77 (2%)

Query: 132 EPLSQESEVEEPLSQES-QVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPLSQESQV 190
           EP +Q  E  E +   S Q E P      +EE  S   Q    L  ES ME       +V
Sbjct: 221 EPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEV 280

Query: 191 E-EPPSQESEMEELPSV 206
             +PP ++     LP++
Sbjct: 281 SVQPPGEDQAYYHLPNI 297



 Score = 28.9 bits (63), Expect = 3.2
 Identities = 32/121 (26%), Positives = 45/121 (37%), Gaps = 6/121 (4%)

Query: 56  ATKMAAVTAPEAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLS 115
           A+   +V  P+ +   AA  PS +    L   E       S      P  Q      PL 
Sbjct: 406 ASPSVSVKPPDVQLTIAAE-PSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGG--PPLL 462

Query: 116 QESEVEE-PLS--QESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEE 172
            ES  E  PL+  QE+  + P    +E   P  QE+  E P + E        QE+  + 
Sbjct: 463 PESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQT 522

Query: 173 P 173
           P
Sbjct: 523 P 523


>gi|110665701 leucine rich repeat containing 37A [Homo sapiens]
          Length = 1700

 Score = 50.8 bits (120), Expect = 8e-07
 Identities = 37/130 (28%), Positives = 59/130 (45%), Gaps = 4/130 (3%)

Query: 68  ESAPAAPGPSDQPSQELPQHELPPEEP-VSEGTQHDP--LSQEAELEEPLSQESEVEEPL 124
           + APA P  S   S  LP HE+  + P   +   H P    + A++E  ++ E    E  
Sbjct: 259 QEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEP-TNETE 317

Query: 125 SQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPL 184
           S ++Q E P+    EVE   +Q+    EP     E E  +S++ Q  +P     E+E   
Sbjct: 318 SSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREVESSP 377

Query: 185 SQESQVEEPP 194
           +Q+    +PP
Sbjct: 378 TQQETPGQPP 387



 Score = 33.1 bits (74), Expect = 0.17
 Identities = 32/122 (26%), Positives = 51/122 (41%), Gaps = 6/122 (4%)

Query: 86  QHELPPEEPVSEGTQHDPLS--QEAELEEPLSQESEVEEPLSQESQVEEPLSQESEVEEP 143
           QH  PP  P S   +  PL+  QE   + P    +E   P  QE+  E P + E      
Sbjct: 455 QHGGPPLLPESS-EEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSL 513

Query: 144 LSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPLSQESQVEEPPSQESEMEEL 203
             QE+  + P      V +P  + S + +   Q  ++   ++ ES+ E   S    M+E 
Sbjct: 514 THQEAPAQTPEFPNVVVAQP-PEHSHLTQATVQPLDLGFTITPESKTEVELS--PTMKET 570

Query: 204 PS 205
           P+
Sbjct: 571 PT 572



 Score = 30.8 bits (68), Expect = 0.85
 Identities = 23/77 (29%), Positives = 32/77 (41%), Gaps = 2/77 (2%)

Query: 132 EPLSQESEVEEPLSQES-QVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPLSQESQV 190
           EP +Q  E  E +   S Q E P      +EE  S   Q    L  ES ME       +V
Sbjct: 221 EPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEV 280

Query: 191 E-EPPSQESEMEELPSV 206
             +PP ++     LP++
Sbjct: 281 SVQPPGEDQAYYHLPNI 297



 Score = 28.9 bits (63), Expect = 3.2
 Identities = 32/121 (26%), Positives = 45/121 (37%), Gaps = 6/121 (4%)

Query: 56  ATKMAAVTAPEAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLS 115
           A+   +V  P+ +   AA  PS +    L   E       S      P  Q      PL 
Sbjct: 406 ASPSVSVKPPDVQLTIAAE-PSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGG--PPLL 462

Query: 116 QESEVEE-PLS--QESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEE 172
            ES  E  PL+  QE+  + P    +E   P  QE+  E P + E        QE+  + 
Sbjct: 463 PESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQT 522

Query: 173 P 173
           P
Sbjct: 523 P 523


>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
          Length = 841

 Score = 50.1 bits (118), Expect = 1e-06
 Identities = 48/218 (22%), Positives = 83/218 (38%), Gaps = 23/218 (10%)

Query: 3   PKPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMAAV 62
           P PR +    K     K ++   PS + P+ K+    +               +   +  
Sbjct: 495 PSPRGTTASPKGRVRRKEEAKESPSAAGPEDKSQSKRRASNEKESAAPASPAPSPAPSPT 554

Query: 63  TAPEAESAPAAPGPSDQ---PSQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESE 119
            AP  +  P A  P+D     S   P   + P +P++  T  +  ++   L E   Q  E
Sbjct: 555 PAPPQKEQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEATR--LLAEKRRQARE 612

Query: 120 VEEPLSQESQV---------EEPLSQES------EVEEPLSQESQVEEPLSQESEVEEPL 164
             E   QE ++         EE L++E+      E E    +E +  E    E E +E L
Sbjct: 613 QREREEQERRLQAERDKRMREEQLAREAEARAEREAEARRREEQEAREKAQAEQEEQERL 672

Query: 165 SQESQVEEPLSQESEMEEPLSQESQVEEPPSQESEMEE 202
            ++ +  E  S+E    + L +E   ++   QE E +E
Sbjct: 673 QKQKEEAEARSREEAERQRLEREKHFQQ---QEQERQE 707



 Score = 47.8 bits (112), Expect = 7e-06
 Identities = 48/176 (27%), Positives = 74/176 (42%), Gaps = 21/176 (11%)

Query: 4   KPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAA------T 57
           KP A G PA      +R  +S     + K K  +  K+  A+ R R  KK  +       
Sbjct: 393 KPNAGGSPAPVR---RRPEASPVQKKEKKDKERENEKEKSALARERSLKKRQSLPASPRA 449

Query: 58  KMAAVTA----PEAESAPAAPGPS-DQPSQELPQ----HELPPEEPVSEGTQHDPLSQEA 108
           +++A TA    P++++ P++P  S  +P+   P     H LPP+ P   GT   P  +  
Sbjct: 450 RLSASTASELSPKSKARPSSPSTSWHRPASPCPSPGPGHTLPPKPPSPRGTTASPKGRVR 509

Query: 109 ELEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLS-QESQVEEPLSQESEVEEP 163
             EE  ++ES        +SQ +   S E E   P S   S    P     + E+P
Sbjct: 510 RKEE--AKESPSAAGPEDKSQSKRRASNEKESAAPASPAPSPAPSPTPAPPQKEQP 563



 Score = 37.7 bits (86), Expect = 0.007
 Identities = 48/225 (21%), Positives = 86/225 (38%), Gaps = 29/225 (12%)

Query: 5   PRASGPPAKA-TEAGKRKSSSQPSP-----------SDPKKKTTKVAKKGKAVRRGR--- 49
           P+   PPA+  T+A    S   P+P           +D ++ T  +A+K +  R  R   
Sbjct: 558 PQKEQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEATRLLAEKRRQAREQRERE 617

Query: 50  ---------RGKKGAATKMAAVTAPEAESAPAAPGPSDQPSQELPQHELPPEEPVSEGTQ 100
                    R K+    ++A      AE    A    +Q ++E  Q E   +E + +  +
Sbjct: 618 EQERRLQAERDKRMREEQLAREAEARAEREAEARRREEQEAREKAQAEQEEQERLQKQKE 677

Query: 101 HDPLSQEAELEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEV 160
               ++    EE   Q  E E+   Q+ Q  +   +  E     +++S+V E   ++   
Sbjct: 678 E---AEARSREEAERQRLEREKHFQQQEQERQERRKRLEEIMKRTRKSEVSETKQKQDSK 734

Query: 161 EEPLSQESQVEEPLSQESEMEEPLSQESQVEEPPSQESEMEELPS 205
           E   +  S   EP+         L +E+  +E P  +     LPS
Sbjct: 735 EANANGSSP--EPVKAVEARSPGLQKEAVQKEEPIPQEPQWSLPS 777



 Score = 31.2 bits (69), Expect = 0.65
 Identities = 35/147 (23%), Positives = 54/147 (36%), Gaps = 5/147 (3%)

Query: 48  GRRGKKGAATKMAAV--TAPEAESAPAA-PGPSDQPSQELPQHELPPEEPVSEGTQHDPL 104
           G R + GA    A V  T PE   +P   P P   P   L   + PP+ P +        
Sbjct: 4   GPRAELGAGAPPAVVARTPPEPRPSPEGDPSPPPPPMSALVP-DTPPDTPPAMKNATSSK 62

Query: 105 SQEAELEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPL 164
               E E P  Q      P  +ES   E  S+         ++++     SQ S    P 
Sbjct: 63  QLPLEPESPSGQVGPRPAPPQEESPSSEAKSRGPTPPAMGPRDARPPRRSSQPSPTAVPA 122

Query: 165 SQESQVEEPLSQESEMEEPLSQESQVE 191
           S     ++ + +  E  + L++E + E
Sbjct: 123 SDSPPTKQEVKKAGERHK-LAKERREE 148


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.291    0.113    0.290 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,201,839
Number of Sequences: 37866
Number of extensions: 579098
Number of successful extensions: 11377
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 536
Number of HSP's successfully gapped in prelim test: 1101
Number of HSP's that attempted gapping in prelim test: 4563
Number of HSP's gapped (non-prelim): 5180
length of query: 206
length of database: 18,247,518
effective HSP length: 97
effective length of query: 109
effective length of database: 14,574,516
effective search space: 1588622244
effective search space used: 1588622244
T: 11
A: 40
X1: 17 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 44 (21.6 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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