BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|66730423 hypothetical protein LOC389384 [Homo sapiens] (652 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|66730423 hypothetical protein LOC389384 [Homo sapiens] 1324 0.0 gi|17136078 VGF nerve growth factor inducible precursor [Homo sa... 51 4e-06 gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 49 1e-05 gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 47 7e-05 gi|148806908 fibronectin type III domain containing 1 [Homo sapi... 46 1e-04 gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 45 2e-04 gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 44 4e-04 gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 44 6e-04 gi|83921602 solute carrier family 38, member 10 isoform a [Homo ... 43 8e-04 gi|153070256 MAGI family member, X-linked isoform d [Homo sapiens] 43 8e-04 gi|153945728 microtubule-associated protein 1B [Homo sapiens] 43 0.001 gi|154816198 transcription elongation factor B polypeptide 3C-li... 43 0.001 gi|156938279 transcription elongation factor B polypeptide 3C [H... 43 0.001 gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens] 42 0.001 gi|118498345 AT-binding transcription factor 1 [Homo sapiens] 42 0.002 gi|58331242 formin homology 2 domain containing 3 [Homo sapiens] 41 0.003 gi|21493022 A kinase (PRKA) anchor protein 12 isoform 1 [Homo sa... 41 0.003 gi|21493024 A kinase (PRKA) anchor protein 12 isoform 2 [Homo sa... 41 0.003 gi|11968023 zinc finger protein 106 homolog [Homo sapiens] 41 0.003 gi|19923167 tubby isoform a [Homo sapiens] 41 0.004 gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo... 41 0.004 gi|50428935 BPY2 interacting protein 1 [Homo sapiens] 41 0.004 gi|151301137 AT-hook transcription factor [Homo sapiens] 40 0.005 gi|29789008 Huntingtin interacting protein C isoform 2 [Homo sap... 40 0.005 gi|72534686 Huntingtin interacting protein C isoform 1 [Homo sap... 40 0.005 gi|38201621 eukaryotic translation initiation factor 4 gamma, 1 ... 40 0.009 gi|38201627 eukaryotic translation initiation factor 4 gamma, 1 ... 40 0.009 gi|38201623 eukaryotic translation initiation factor 4 gamma, 1 ... 40 0.009 gi|150378543 MYST histone acetyltransferase (monocytic leukemia)... 40 0.009 gi|150378463 MYST histone acetyltransferase (monocytic leukemia)... 40 0.009 >gi|66730423 hypothetical protein LOC389384 [Homo sapiens] Length = 652 Score = 1324 bits (3427), Expect = 0.0 Identities = 652/652 (100%), Positives = 652/652 (100%) Query: 1 MENPRCPRRPLAEKKARSLDRPQAPGKGSESWDCHWLSLPTAPSRKALHWTTSDWARHSD 60 MENPRCPRRPLAEKKARSLDRPQAPGKGSESWDCHWLSLPTAPSRKALHWTTSDWARHSD Sbjct: 1 MENPRCPRRPLAEKKARSLDRPQAPGKGSESWDCHWLSLPTAPSRKALHWTTSDWARHSD 60 Query: 61 SPAPSAEAHCTTAAAPTPEETGDFLPSEQRPSQDTKKGWLKTMLNFFVRTGPEEPRERAS 120 SPAPSAEAHCTTAAAPTPEETGDFLPSEQRPSQDTKKGWLKTMLNFFVRTGPEEPRERAS Sbjct: 61 SPAPSAEAHCTTAAAPTPEETGDFLPSEQRPSQDTKKGWLKTMLNFFVRTGPEEPRERAS 120 Query: 121 RRPRGKEGISQHPEPLEAAGEPALRKKAHHDKKPSRKKQGHKKHAAEVTKAAQDQEARGR 180 RRPRGKEGISQHPEPLEAAGEPALRKKAHHDKKPSRKKQGHKKHAAEVTKAAQDQEARGR Sbjct: 121 RRPRGKEGISQHPEPLEAAGEPALRKKAHHDKKPSRKKQGHKKHAAEVTKAAQDQEARGR 180 Query: 181 EEGLSKAAAALRSGEADLGPARRGGEDSDHQSFLIKVDGTGALDVSPHATGHQQEEELKK 240 EEGLSKAAAALRSGEADLGPARRGGEDSDHQSFLIKVDGTGALDVSPHATGHQQEEELKK Sbjct: 181 EEGLSKAAAALRSGEADLGPARRGGEDSDHQSFLIKVDGTGALDVSPHATGHQQEEELKK 240 Query: 241 PDQDAIIQMIVELLKRVGDQWEEEQSLASQLGVALPNPAPAVRKKSQEKKTSLKRTSKTN 300 PDQDAIIQMIVELLKRVGDQWEEEQSLASQLGVALPNPAPAVRKKSQEKKTSLKRTSKTN Sbjct: 241 PDQDAIIQMIVELLKRVGDQWEEEQSLASQLGVALPNPAPAVRKKSQEKKTSLKRTSKTN 300 Query: 301 PKKHGSEEAKRGAADVSSPEAWPPKKSSFLPLCVSGHRPSISSSYGLEEPKVQEAPSTEA 360 PKKHGSEEAKRGAADVSSPEAWPPKKSSFLPLCVSGHRPSISSSYGLEEPKVQEAPSTEA Sbjct: 301 PKKHGSEEAKRGAADVSSPEAWPPKKSSFLPLCVSGHRPSISSSYGLEEPKVQEAPSTEA 360 Query: 361 GAPGPSVLPTPSESQEPGEELPLDRASEYKEFIQKIISMLQDAEEQQGEEQPQVQQEEVG 420 GAPGPSVLPTPSESQEPGEELPLDRASEYKEFIQKIISMLQDAEEQQGEEQPQVQQEEVG Sbjct: 361 GAPGPSVLPTPSESQEPGEELPLDRASEYKEFIQKIISMLQDAEEQQGEEQPQVQQEEVG 420 Query: 421 VENPAPHCRRKSQEKRSSFRRAFYHKKHTSKEPRRAGAAGAASPEARRPKRPSFLPLCVG 480 VENPAPHCRRKSQEKRSSFRRAFYHKKHTSKEPRRAGAAGAASPEARRPKRPSFLPLCVG Sbjct: 421 VENPAPHCRRKSQEKRSSFRRAFYHKKHTSKEPRRAGAAGAASPEARRPKRPSFLPLCVG 480 Query: 481 GHRPSTSSSLDPEDLECREPLPAEGEPVVISEAPSQARGHTPEGAPQLSGACESKEIIIQ 540 GHRPSTSSSLDPEDLECREPLPAEGEPVVISEAPSQARGHTPEGAPQLSGACESKEIIIQ Sbjct: 481 GHRPSTSSSLDPEDLECREPLPAEGEPVVISEAPSQARGHTPEGAPQLSGACESKEIIIQ 540 Query: 541 KLVALLQEVDGQLGQQIRRHPSFKRFFYEFSDSPLSKLVATLRSQVAHSSKLDRNRARRL 600 KLVALLQEVDGQLGQQIRRHPSFKRFFYEFSDSPLSKLVATLRSQVAHSSKLDRNRARRL Sbjct: 541 KLVALLQEVDGQLGQQIRRHPSFKRFFYEFSDSPLSKLVATLRSQVAHSSKLDRNRARRL 600 Query: 601 YQFDVSLANKFAGSNSHAMCILMGLRDHYNCTQFPYREDQPNITSPKVESPD 652 YQFDVSLANKFAGSNSHAMCILMGLRDHYNCTQFPYREDQPNITSPKVESPD Sbjct: 601 YQFDVSLANKFAGSNSHAMCILMGLRDHYNCTQFPYREDQPNITSPKVESPD 652 >gi|17136078 VGF nerve growth factor inducible precursor [Homo sapiens] Length = 615 Score = 50.8 bits (120), Expect = 4e-06 Identities = 114/543 (20%), Positives = 187/543 (34%), Gaps = 109/543 (20%) Query: 9 RPLAEKKARSLDRPQAPGKGSESWDCHWLSLPTAPSRKALHWTTSDWARHS----DSPAP 64 R LA ++LDRP +P S S P + +AL T HS +SP P Sbjct: 80 RALAAVLLQALDRPASPPAPSGSQQG-----PEEEAAEALLTETVRSQTHSLPAPESPEP 134 Query: 65 SAEAHCTT---------------AAAPTPEETGDFLPSEQRPSQDTKKGWLKTMLNFFVR 109 +A T A A +E DF PS + Q+T +T + R Sbjct: 135 AAPPRPQTPENGPEASDPSEELEALASLLQELRDFSPSSAKRQQETAAAETETRTHTLTR 194 Query: 110 TGPEEPRERASRRPRGKEGISQHPE--------------------PLEAA---GEPALRK 146 E P R E ++ PE PL GE Sbjct: 195 VNLESPGPERVWRASWGEFQARVPERAPLPPPAPSQFQARMPDSGPLPETHKFGEGVSSP 254 Query: 147 KAHHDKKPSRKKQGHKKHAAEVTKAAQDQEA---------RGREEGLSKAAAALRSGEAD 197 K H + + + ++ AA KA + + A R ++GL++ A R EA Sbjct: 255 KTHLGEALAPLSKAYQGVAAPFPKARRPESALLGGSEAGERLLQQGLAQVEAGRRQAEAT 314 Query: 198 LGPARRGGEDSDHQSFLI------------KVDGTGALDVSPHATGHQQEEELKKPDQDA 245 A + +D S L+ + G G + + ++EEE ++ + Sbjct: 315 RQAAAQEERLADLASDLLLQYLLQGGARQRGLGGRGLQEAAEERESAREEEEAEQERRGG 374 Query: 246 IIQMIVELLKRVGDQWE---EEQSLASQLGVALPNPAPAVRKKSQEKKTSLKRTSKTNP- 301 +RVG++ E E ++ A + A N ++ E KR+ + P Sbjct: 375 --------EERVGEEDEEAAEAEAEAEEAERARQNALLFAEEEDGEAGAEDKRSQEETPG 426 Query: 302 -KKHGSEEAKRGAADVSSPEAWPPKKSSFLPLCVSGHRPS---ISSSYGLEEPKVQEAPS 357 ++ +E + G + E P S + L H P+ +S +EE + ++ + Sbjct: 427 HRRKEAEGTEEGGEEEDDEEMDPQTIDSLIELSTKLHLPADDVVSIIEEVEEKRKRKKNA 486 Query: 358 TEAGAPGPSVLPTPSESQEPGEELPLDRASEYKEFIQKIISMLQDAEEQQGEEQPQVQQE 417 P P P P+ + P P + +D E P +E Sbjct: 487 PPEPVPPPRAAPAPTHVRSPQPPPPAPAPA-------------RDELPDWNEVLPPWDRE 533 Query: 418 EVGVENPAP------HCRRKSQEKRSSFRRAFYH------KKHTSKEPRRAGAAGAASPE 465 E V P P + R ++ + S+ RR YH + + +E + A A E Sbjct: 534 EDEVYPPGPYHPFPNYIRPRTLQPPSALRRRHYHHALPPSRHYPGREAQARRAQEEAEAE 593 Query: 466 ARR 468 RR Sbjct: 594 ERR 596 >gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] Length = 1020 Score = 49.3 bits (116), Expect = 1e-05 Identities = 86/390 (22%), Positives = 145/390 (37%), Gaps = 33/390 (8%) Query: 114 EPRERASRRPRGKEGISQHPEPL----EAAGEPALRKKAHHD--KKPSRKKQGHKKHAAE 167 E E ++ P +E S E E A PA K + K P+ K K + Sbjct: 495 EGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPA 554 Query: 168 VTKAAQDQEARGREEGLSKAAAALRSGEADLGPARRGGEDSDHQSFLIKVDGTGALDV-S 226 +A EA+ E+ +K+ A ++S E PA+ + K + S Sbjct: 555 KEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKS 614 Query: 227 PHATGHQQEEELKKPDQDAIIQMIVELLKRVGDQWEEEQSLASQLGVA---LPNPAPAVR 283 P +EE K P + + K E+ +S + + +P A Sbjct: 615 PAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEA 674 Query: 284 KKSQEKKTSLKRTSKTNPK-KHGSEEAKRGAADVSSP---EAWPPKKSSFLPLCVSGHRP 339 K ++ K+ +K +K+ K K +E + SP EA P+K+ P+ P Sbjct: 675 KSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAK-SPVKEEAKTP 733 Query: 340 SISSSYGLEEPKVQEAPSTEAGAPGPSV------LPTPSESQEPGEELPLDRASEYKEFI 393 + S EE K E + A V P E++ P ++ P S KE + Sbjct: 734 EKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEV 793 Query: 394 ---QKIISMLQDAEEQQGEEQPQ-------VQQEEVGVENPAPHCRRKSQEKRSSFRRAF 443 +K S L++ + +E P+ V++EE E +K++E+++ Sbjct: 794 KSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKT 853 Query: 444 YHKKHTSKEPRRAGAAGAASPEARRPKRPS 473 KK + KE A A P+ K P+ Sbjct: 854 EEKKDSKKE--EAPKKEAPKPKVEEKKEPA 881 Score = 47.8 bits (112), Expect = 3e-05 Identities = 85/433 (19%), Positives = 156/433 (36%), Gaps = 58/433 (13%) Query: 63 APSAEAHCTTAAAPTPEETGDFLPSEQRPSQDTKKGWLKTMLNFFVRTGPEEPRERASRR 122 +P+ E + A A +PE+ + E + + K + + PE+ + Sbjct: 586 SPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEE 645 Query: 123 PRGKEGISQHPEPLEAAG-EPALRKKAHHDKKPSRKKQGHKKHAA--EVTKAAQDQEARG 179 + E ++ PE EA E A K P + K K A E K+ +EA+ Sbjct: 646 AKSPEK-AKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKS 704 Query: 180 REEGLSKAAAALRSGEADLGPARRGGEDSDHQSFLIKVDGTGALDVSPHATGHQQEEELK 239 E+ S +S E P + + + +K + + E+ K Sbjct: 705 PEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEA-------------KSPEKAK 751 Query: 240 KPDQDAIIQMIVELLKRVGDQWEEEQSLASQLGVALPNPAPAVRKKSQEKKTSLKRTSKT 299 P++ + + K EE +S A + +P K ++ K+ LK +K Sbjct: 752 SPEKAKTLDVKSPEAKTPAK--EEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKA 809 Query: 300 NPKK-HGSEEAKRGAADVSSPEAW----PPKKSSFLPLCVSGHRPSISSSYGLEEPKVQE 354 K+ EE K + P+ PPKK+ P+ + ++ K +E Sbjct: 810 PEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAE------EEKAPATPKTEEKKDSKKEE 863 Query: 355 APSTEAGAPGPSVLPTPSESQEPGEELPLDRASEYKEFIQKI----------ISMLQDAE 404 AP EA P P V + E +E ++ E E +K+ + + +DA+ Sbjct: 864 APKKEA--PKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAK 921 Query: 405 EQQGEEQPQVQQEEVGVENPAPHCRRKS----------------QEKRSSFRRAFYHKKH 448 ++ E + + ++ + P+ +K +EK + +A K Sbjct: 922 PKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKT 981 Query: 449 TSKEPRRAGAAGA 461 SKEP + A A Sbjct: 982 LSKEPSKPKAEKA 994 Score = 44.3 bits (103), Expect = 4e-04 Identities = 58/248 (23%), Positives = 94/248 (37%), Gaps = 10/248 (4%) Query: 286 SQEKKTSLKRTSKTNPKKHGSEEAKRGAADVSSP---EAWPPKKSSFLPLCVSGHRPSIS 342 ++E++ K + EEA+ G + SP EA P+K + P+ P+ + Sbjct: 471 TEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEA 530 Query: 343 SSYGLEEPKVQ-EAPSTE-AGAPGPSVLPTPSESQEPGEELPLDRASEYKEFIQKIISML 400 S EE K E S E A +P +P E++ P +E A E K + Sbjct: 531 KSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPA-EVKSPEKAKSPAK 589 Query: 401 QDAEEQQGEEQPQVQQEEVGVENPAPHCRRKSQEKRSSFRRAFYHKKHTSKEPRRAGAAG 460 ++A+ + P+ + V E +P KS K + A +K P + A Sbjct: 590 EEAKSPAEAKSPEKAKSPVKEEAKSP-AEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKS 648 Query: 461 ---AASPEARRPKRPSFLPLCVGGHRPSTSSSLDPEDLECREPLPAEGEPVVISEAPSQA 517 A SPE K P V S + P E + P A+ +++P +A Sbjct: 649 PEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKA 708 Query: 518 RGHTPEGA 525 + E A Sbjct: 709 KSPVKEEA 716 Score = 34.7 bits (78), Expect = 0.28 Identities = 39/190 (20%), Positives = 80/190 (42%), Gaps = 20/190 (10%) Query: 13 EKKARSLDRPQAPGKGSESWDCHWLSLPTAPSRKALHWTTSDWARHSDSPAPSAEAHCTT 72 E+K + + + P K E P P + + + A ++P P E Sbjct: 827 EEKPQEVKVKEPPKKAEEE------KAPATPKTEEKKDSKKEEAPKKEAPKPKVEEK-KE 879 Query: 73 AAAPTPEETGDFLPSEQRPSQDTKKGWLKTMLNFFVRTGPEEPRERASRRPRGKEGISQ- 131 A P+E+ + +++ ++D KK + + P + + +P+ K +++ Sbjct: 880 PAVEKPKESK--VEAKKEEAEDKKK------VPTPEKEAPAKVEVKEDAKPKEKTEVAKK 931 Query: 132 HPEPLEAA--GEPALRKKAHHDKKPSRKKQGHKKHAAEVT--KAAQDQEARGREEGLSKA 187 P+ +A +PA +K+A +KK +++++ K T KA +D + +E KA Sbjct: 932 EPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKA 991 Query: 188 AAALRSGEAD 197 A +S D Sbjct: 992 EKAEKSSSTD 1001 Score = 30.0 bits (66), Expect = 7.0 Identities = 46/215 (21%), Positives = 81/215 (37%), Gaps = 27/215 (12%) Query: 115 PRERASRRPRGKEGISQHPEPLEA-AGEPALRKKAHHDKKPSRKKQGHKKHAAEVTKAAQ 173 P + ++ K + + +P E EP KKA +K P+ K KK + + + A Sbjct: 810 PEKEIPKKEEVKSPVKEEEKPQEVKVKEPP--KKAEEEKAPATPKTEEKKDSKK--EEAP 865 Query: 174 DQEARGREEGLSKAAAALRSGEADLGPARRGGEDSDHQSFLIKVDGTGALDVSPHATGHQ 233 +EA + K A + E+ + + ED K + ++V A + Sbjct: 866 KKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEK-EAPAKVEVKEDAKPKE 924 Query: 234 QEEELKKPDQDAIIQMIVELLKRVGDQWEEEQSLASQLGVALPNPAPAVRKKSQEKKTSL 293 + E KK DA + E S ++ A P KK +++ + Sbjct: 925 KTEVAKKEPDDAKAK---------------EPSKPAEKKEAAPE------KKDTKEEKAK 963 Query: 294 KRTSKTNPKKHGSEEAKRGAADVSSPEAWPPKKSS 328 K K + E+ K + + S P+A +KSS Sbjct: 964 KPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSS 998 >gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] Length = 2400 Score = 46.6 bits (109), Expect = 7e-05 Identities = 106/501 (21%), Positives = 181/501 (36%), Gaps = 82/501 (16%) Query: 53 SDWARHSDSPAPSAEAHCTTAAAPTPEETGDFLPSE---QRPSQDTKKGWLKTMLNFFVR 109 SD A ++P EA + PE GD +E Q S+D + + Sbjct: 1829 SDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAE-------- 1880 Query: 110 TGPEEPRERASRRPRGKEGISQHPEPLEAAGEPALRKKAHHDKK--PSRKKQGHKKHAAE 167 G +P P + + E EA P K+A + + + + +G + +E Sbjct: 1881 -GEAQPESEDVETPEAEWEVQPESEGAEA---PEAEKEAQPETESVEALETEGEDEPESE 1936 Query: 168 VTKAAQDQEARGREEGLSK-AAAALRSGEADLGPARRGGEDSDHQSFLIKVDGTGALDVS 226 +A + +EA EG ++ + + S EA+ E D ++ ++V+ A Sbjct: 1937 GAEAQEAEEAAQEAEGQTQPESEVIESQEAE---EEAQPESEDVEALEVEVETQEA---- 1989 Query: 227 PHATGHQQEEELKKPDQDAIIQMIVELLKRVGDQWEEEQSLASQLGVALPNPAPAVRKKS 286 + E+++ P+ + +Q E + D E + + A V ++ Sbjct: 1990 -EGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGE-------EAQEVEGET 2041 Query: 287 QEKKTSLKRTSKTNPKKHGSEEAKRGAADVSSPEAWPPKKSSFLPLCVSGHRPSISSSYG 346 Q+ + + S EEA+ +V E +S + + S G Sbjct: 2042 QKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVD-AQEAEGEAQPESEG 2100 Query: 347 LEEPKVQ---------EAPSTEAGA-PGPSVLPTPSESQEPGEELPLDRASEYKEFIQKI 396 +E P+ + EAP TE A P + P + GE P E ++ + Sbjct: 2101 VEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAP---EAEGEAQPESEGVEAQDAEGEA 2157 Query: 397 ISMLQDAEEQQGEEQPQVQQEEVGVENPAPHCRRKSQEKRSSFRRAFYHKKHTSKEPRRA 456 + E Q+ EE+ Q + E GVE AP ++Q + Sbjct: 2158 QPESEGIEAQEAEEEAQPELE--GVE--APEAEGEAQPE--------------------- 2192 Query: 457 GAAGAASPEARRPKRPSFLPLCVGGHRPSTSSSLDPEDLECREPLPAEGEPVVISEAPSQ 516 + G +PEA +P G P PE E E AEGE SE +Q Sbjct: 2193 -SEGIEAPEAEGEAQPEL----EGVEAPEAEEEAQPEP-EGVETPEAEGEAQPESEGETQ 2246 Query: 517 ARGHTPEGAPQLS-GACESKE 536 +G+PQ+S G +S+E Sbjct: 2247 GE---KKGSPQVSLGDGQSEE 2264 >gi|148806908 fibronectin type III domain containing 1 [Homo sapiens] Length = 1894 Score = 45.8 bits (107), Expect = 1e-04 Identities = 112/542 (20%), Positives = 182/542 (33%), Gaps = 108/542 (19%) Query: 37 LSLPTAPSRKALHWTTSDWARHSDSPAPSAEAHCTTAAAPTPEETGDFLPSEQRPSQDTK 96 +++PT S+ + T D + + P PS+ + A++ P +P+ P Sbjct: 452 VAMPTT-SKADVEQNTEDNGK-PEKPEPSSPSPRAPASSQHPS-----VPAS--PQGRNA 502 Query: 97 KGWLKTMLNFFVRTG--PEEPRERASRRPRGKEGISQHPEPLEAAGEPALRKKAHHDKKP 154 K L + N + G P +P+ RA K+ + E GE L + P Sbjct: 503 KDLLLDLKNKILANGGAPRKPQLRA------KKAEELDLQSTEITGEEELGSREDSPMSP 556 Query: 155 SR-----------KKQGHKKHAAEVTKAAQDQEARGREEGLSKAAAALRSGEADLGPARR 203 S + GH A T A R EG+ K +L + P Sbjct: 557 SDTQDQKRTLRPPSRHGHSVVAPGRTAVRARMPALPRREGVDKPGFSLATQPRPGAPPSA 616 Query: 204 GGEDSDHQSFLIKVDGTGALDVSPHATGHQQEEELKKPDQDAIIQMIVELLKRVGDQWEE 263 + H S T H+ D D + D E+ Sbjct: 617 SASPAHH--------------ASTQGTSHRPSLPASLNDNDLV------------DSDED 650 Query: 264 EQSLAS-QLGVALPNPAPAVRKKSQEKKTSLKRTSKTNPKKHGSEEAKR----GAADVSS 318 E+++ S A P PA+ Q + L+ S +P + A+R GAA+ S Sbjct: 651 ERAVGSLHPKGAFAQPRPALSPSRQSPSSVLRDRSSVHPGAKPASPARRTPHSGAAEEDS 710 Query: 319 PEAWPPKK--------SSFLPLCVSGHRPSISSSYGLEEPKVQEAPSTEAGAPGPSVLPT 370 + PP + S LP +P +SS ++AP+T + AP S + Sbjct: 711 SASAPPSRLSPPHGGSSRLLPT-----QPHLSSPLSKGGKDGEDAPATNSNAPSRSTM-- 763 Query: 371 PSESQEPGEELPLDRASEYKEFIQKIISMLQDAEEQQGEEQPQVQQEEVGVENPAPHCRR 430 +S + + + AE GE +E+ G + A Sbjct: 764 ---------------SSSVSSHLSSRTQVSEGAEASDGESHGDGDREDGGRQAEATAQTL 808 Query: 431 KSQEKRSSFRRAFYHKKHTS--KEPRRAGAA------GAASPEARRPKRPSFLPLCVGGH 482 +++ F HK + + P R ++SP++ P R Sbjct: 809 RARPASGHF-HLLRHKPFAANGRSPSRFSIGRGPRLQPSSSPQSTVPSRAHPRVPSHSDS 867 Query: 483 RPSTSSSLDPEDLECREPLPAEGEPVVISEAPSQARGHTPEG------APQLSGACESKE 536 P SS + ++ E +PLPA VV PS +R G +PQ + KE Sbjct: 868 HPKLSSGIHGDE-EDEKPLPA---TVVNDHVPSSSRQPISRGWEDLRRSPQRGASLHRKE 923 Query: 537 II 538 I Sbjct: 924 PI 925 Score = 38.1 bits (87), Expect = 0.026 Identities = 63/285 (22%), Positives = 91/285 (31%), Gaps = 52/285 (18%) Query: 279 APAVRKKSQEKKTSLKRTSKTNPKKHGSEEAKRGAADVSSPEAWPPKKSSFLPLCVSGHR 338 +P + S ++ S R ++H S R +P+ PP P+ S H Sbjct: 964 SPKAQPGSTDRHASPARPPAARSQQHPS--VPRRMTPGRAPQQQPPP-----PVATSQHH 1016 Query: 339 PSISSSYGLEEPKVQEAPSTEAGAPGPSVLPTPSESQEPGEELPLDRASEYKEFIQKIIS 398 P S P T+AG P P+ S +P + Sbjct: 1017 PGPQSRDAGRSPSQPRLSLTQAGRPRPTSQGRSHSSSDP--------------YTASSRG 1062 Query: 399 MLQDAEEQQGEEQPQVQQEEVGVENPAPHCRRKSQEKRSSFRRAFYHKKHTSKEPRRAGA 458 ML A + Q +E Q ++ E A R + R+ A K + P AGA Sbjct: 1063 MLPTALQNQ-DEDAQGSYDDDSTEVEAQDVRAPAHAARAKEAAASLPKHQQVESPTGAGA 1121 Query: 459 AG--------AASP-----------EARRPKR--------PSFLPLCVGGHRPSTSSSLD 491 G AASP AR P R PS PL + S S + Sbjct: 1122 GGDHRSQRGHAASPARPSRPGGPQSRARVPSRAAPGKSEPPSKRPL---SSKSQQSVSAE 1178 Query: 492 PEDLECREPLPAEGEPVVISEAPSQARGHTPEGAPQLSGACESKE 536 ++ E E ++ S P TP G G+ +E Sbjct: 1179 DDEEEDAGFFKGGKEDLLSSSVPKWPSSSTPRGGKDADGSLAKEE 1223 >gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapiens] Length = 1341 Score = 45.1 bits (105), Expect = 2e-04 Identities = 84/376 (22%), Positives = 140/376 (37%), Gaps = 46/376 (12%) Query: 186 KAAAALRSGEADLGPARRGGEDSDHQSFLIK-VDGTGALD-----VSPHATGHQQEEELK 239 K ALR + +RG S +S L+K + G L+ +PHA + + Sbjct: 70 KPLQALRVTDLKAALEQRGLAKSGQKSALVKRLKGALMLENLQKHSTPHAAFQPNSQIGE 129 Query: 240 KPDQDAIIQMIVEL--------LKRVGDQWEEEQSLASQLGVALPNPAPAVRKKSQEKKT 291 + Q++ I+ +E L+R + E + +++ + +P + ++ Sbjct: 130 EMSQNSFIKQYLEKQQELLRQRLEREAREAAELEEASAESEDEMIHPEGVASLLPPDFQS 189 Query: 292 SLKRT----SKTNPKKHGSEEAKRGAADVSSPEAWPPKKSSFLPLCVSGHRPSISSSYGL 347 SL+R S+ +P+K S ++G +D P + S + S Sbjct: 190 SLERPELELSRHSPRKSSSISEEKGDSDDEKPRKGERRSSRVRQARAA---KLSEGSQPA 246 Query: 348 EEPKVQEAPSTEAGAPGPSVLPTPSESQEPGEELPLDRASEYKEFIQKI--ISMLQDAEE 405 EE + QE PS L T E +E EE D E + QK +L++ +E Sbjct: 247 EEEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKE 306 Query: 406 QQGEEQPQVQQEEVGVENPAPH-------------CRRKSQEKRSSFRRAFYHKKHTSKE 452 + GEE P+V+ EE+ E P R + + ++S R K+ + Sbjct: 307 E-GEEIPRVKPEEMMDERPKTRSQEQEVLERGGRFTRSQEEARKSHLARQQQEKEMKTTS 365 Query: 453 PRRAGAAGAASPEARRPKRPSFLPLCVGGHRPSTSSSLDPEDLECREPLPAEGEPVVISE 512 P S + + K S P + R S PE E P P++ E Sbjct: 366 PLEEEEREIKSSQGLKEKSKSPSPPRLTEDRKKASLVALPEQTASEEETP---PPLLTKE 422 Query: 513 APSQARGHTPEGAPQL 528 A S P PQL Sbjct: 423 ASS------PPPHPQL 432 >gi|84043963 eukaryotic translation initiation factor 5B [Homo sapiens] Length = 1220 Score = 44.3 bits (103), Expect = 4e-04 Identities = 87/448 (19%), Positives = 163/448 (36%), Gaps = 63/448 (14%) Query: 13 EKKARSLDRPQAPGKGSESWDCHWLSLPTAPSRKALH----WTTSDWARHSDSPAPSAEA 68 + K++ +P+ D + LP KA W S+ D+ E Sbjct: 120 DSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSE--EDEDNSKKIKER 177 Query: 69 HCTTAAAPTPEETGDFLPSEQ--------RPSQDTKKGWLKTMLNFFVRTGPEEPRERAS 120 ++ + +E+ +FL S + +P + + G +F ++T ++ E+ Sbjct: 178 SRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKE 237 Query: 121 RRPRGKEGISQHPEPLEAAGEPALRKKAHHDKKPSRKKQGHKKHAAEVTKAAQDQEARGR 180 R + ++ L+ E KK +K S++K + ++VT Sbjct: 238 RERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVT--VDTGVIPAS 295 Query: 181 EEGLSKAAAALRSGEADL---GPARRGGEDSDHQSFLIKVDGTGALDVSPHATGH-QQEE 236 EE AA E D ++ GE + + K + A ++EE Sbjct: 296 EEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEE 355 Query: 237 ELKKPDQDAIIQMIVELLKRVGDQWEEEQSLASQLGVALPNPAPAVRKKSQEKKTSLKRT 296 E +K +++ I+ + EL + ++ EQ + ++K +E+K LK+ Sbjct: 356 ERQKREEEERIKRLEELEAKRKEEERLEQEKRERK-----------KQKEKERKERLKKE 404 Query: 297 SKTNPKKHGSEEAKRGAA---------DVSSPEAWPPKKSSFLPLCVSGHRPSISSSYGL 347 K K A+ A +V S ++ P K+ P+ R I L Sbjct: 405 GKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKR----PIYEDKKRKKIPQQ--L 458 Query: 348 EEPKVQEAPST-------EAGAPGPSVLPTPSESQEPG----------EELPLDRASEYK 390 E +V E+ E G P P P E +E E + D +E Sbjct: 459 ESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKV 518 Query: 391 EFIQKIISMLQDAEEQQGEEQPQVQQEE 418 E + I + ++ EE++ EE+ + + EE Sbjct: 519 EGNKVHIEVKENPEEEEEEEEEEEEDEE 546 Score = 30.4 bits (67), Expect = 5.3 Identities = 61/324 (18%), Positives = 110/324 (33%), Gaps = 37/324 (11%) Query: 152 KKPSRKKQGHKKHAAEVTKAAQDQEARGREEGLSKAAAALRSGEADLGPARRGGEDSDHQ 211 K +K Q KK + + + + ++ + + +K + SG D D D Sbjct: 94 KDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDD---------DDDFN 144 Query: 212 SFLIKVDGTGALDVSPHATGHQQEEELKKPDQDAIIQMIVELLKRVGDQWEEE-QSLASQ 270 K G + E+ KK + + I E GD+ +E QS Q Sbjct: 145 KLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGES----GDESDEFLQSRKGQ 200 Query: 271 LGVALPNPAPAVRKKSQEKKTSLKRTSKTNPKKHGSEEAKRGAADVSSPEAWPPKKSSFL 330 P P + +++ S K + KK +E +R D + K+ L Sbjct: 201 KKNQKNKPGPNIESGNEDDDASFKIKTVAQ-KKAEKKERERKKRDEEKAKLRKLKEKEEL 259 Query: 331 PLCVSGHRPSISSSYGLEEPKVQEAPSTEAGAPGPSV----LPTPSESQEPGEELPLDRA 386 S EE V+ + + G S PT +E G++ D+ Sbjct: 260 ETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKK 319 Query: 387 SEYKE------------------FIQKIISMLQDAEEQQGEEQPQVQQEEVGVENPAPHC 428 + E +Q+ ++ L++ EE+Q E+ + + +E Sbjct: 320 KKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEE 379 Query: 429 RRKSQEKRSSFRRAFYHKKHTSKE 452 R QEKR ++ +K K+ Sbjct: 380 ERLEQEKRERKKQKEKERKERLKK 403 >gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] Length = 1312 Score = 43.5 bits (101), Expect = 6e-04 Identities = 64/280 (22%), Positives = 110/280 (39%), Gaps = 28/280 (10%) Query: 283 RKKSQEKKTSLKRTSKTNPKKHG------SEEAKRGAADVSSPEAWPPKKSSFLPLCVSG 336 R +S+ + S +R S++ ++ G S E +R +SP PP SS Sbjct: 573 RSRSRSRSRSTRRRSRSTDRRRGGSRRSRSREKRRRRRRSASP---PPATSSSSSSRRER 629 Query: 337 HRPSISSSYGLEEPKVQ-----EAPSTEAGAPGPSVLPTPSESQEPGEELPLDRASEYKE 391 HR G ++ K + E S + P+ P PS S G DR S + Sbjct: 630 HRGKHRDGGGSKKKKKRSRSRGEKRSGDGSEKAPAPAPPPSGSTSCG-----DRDSRRRG 684 Query: 392 FIQKIISMLQDAEE---QQGEEQPQVQQEEVGVENPAPHCRRKSQEKRSSFRRAFYHK-- 446 + I L D + ++ ++ + + +PAP K + S + + Sbjct: 685 AVPPSIQDLTDHDLFAIKRTITVGRLDKSDPRGPSPAPASSPKREVLYDSEGLSGEERGG 744 Query: 447 KHTSKEPRRAGAAGAASPEARRPKRPSFLPLCVGGHRPSTSSSLDPEDLECREPLPAEGE 506 K + K+ RR+GAA ++S + R L GG R D ++ P + E Sbjct: 745 KSSQKDRRRSGAASSSSSSREKGSRRKALD---GGDRDRDRDRDRDRDRSSKKARPPK-E 800 Query: 507 PVVISEAPSQARGHTPEGAPQLSGACESKEIIIQKLVALL 546 S P + + G+ S +C S+++ +Q VA+L Sbjct: 801 SAPSSGPPPKPPVSSGSGSSSSSSSCSSRKVKLQSKVAVL 840 Score = 36.6 bits (83), Expect = 0.075 Identities = 36/146 (24%), Positives = 61/146 (41%), Gaps = 6/146 (4%) Query: 282 VRKKSQEKKTSLKRTSKTNPKKHGSEEAKRGAADVSSPEAWPPKKSSFLPLCVSGHRPSI 341 V+ K+ KKT + KT P K + G + S + K + +G + + Sbjct: 902 VKAKAGAKKTKGTK-GKTKPSKTRKKVRSGGGSGGSGGQVSLKKSKADSCSQAAGTKGAE 960 Query: 342 SSSYGLEE--PKVQEAPSTEAGAPGPSVLPTPSESQEPGEELPLDRASEYKEFIQKIISM 399 +S+ EE KV P +A P P++ P +SQ S E + + Sbjct: 961 ETSWSGEERAAKVPSTPPPKAAPPPPALTP---DSQTVDSSCKTPEVSFLPEEATEEAGV 1017 Query: 400 LQDAEEQQGEEQPQVQQEEVGVENPA 425 AEE++ EE+ + ++EE + PA Sbjct: 1018 RGGAEEEEEEEEEEEEEEEEEEQQPA 1043 Score = 30.8 bits (68), Expect = 4.1 Identities = 66/288 (22%), Positives = 94/288 (32%), Gaps = 41/288 (14%) Query: 272 GVALPNPAPAVRKKSQEKKTSLKRTSKTNPKKHGSEEAKRGAA-DVSSPEAWPPKKSSFL 330 G P PAP+ S S S P + A D+ P + P ++ Sbjct: 182 GGPAPPPAPSSASSSPSPSPSSSSPSPPPPPPPPAPPAPPAPRFDIYDP--FHPTDEAYS 239 Query: 331 PLCVSGHRPSISSSYGLEEPKVQEAPSTEAGAPGPSVLPTPSESQEPGEELPLDRASEYK 390 P P+ Y EP PS+ AG P P E +E EE + E + Sbjct: 240 P------PPAPEQKYDPFEPTGSN-PSSSAGTPSPE-----EEEEEEEEEEEEEEDEEEE 287 Query: 391 EFIQKIISMLQD-----------AEEQQGEEQPQVQQEEVGVENPAPHCRRKSQEKRS-- 437 E + + IS + + +++ G+E P+ + PAP + R+ Sbjct: 288 EGLSQSISRISETLAGIYDDNSLSQDFPGDESPRPDAQPT-QPTPAPGTPPQVDSTRADG 346 Query: 438 SFRRAFYHKKHTSKEPRRAG--------AAGAASPEARRPKRPSFL---PLCVGGHRPST 486 + RR + T E R G A GAA P P S + + P Sbjct: 347 AMRRRVF-VVGTEAEACREGKVSVEVVTAGGAALPPPLLPPGDSEIEEGEIVQPEEEPRL 405 Query: 487 SSSLDPEDLECREPLPAEGEPVVISEAPSQARGHTPEGAPQLSGACES 534 + SL P PA P PEG LS ES Sbjct: 406 ALSLFRPGGRAARPTPAASATPTAQPLPQPPAPRAPEGDDFLSLHAES 453 >gi|83921602 solute carrier family 38, member 10 isoform a [Homo sapiens] Length = 1119 Score = 43.1 bits (100), Expect = 8e-04 Identities = 104/474 (21%), Positives = 171/474 (36%), Gaps = 83/474 (17%) Query: 113 EEPRERASRRPRGKEGISQHPEPLEAAG----EPALRKKAHHDKKPSRKKQGHKKHAAEV 168 E P + A P G+ G ++ +EAA +P + +KP K+ + A++ Sbjct: 400 EVPEDLAEEAPGGRLGEAEGLMKVEAARLSAQDPVVAVAEDGREKPKLPKEREELEQAQI 459 Query: 169 TKAAQDQEARGREEGLSKAAAAL--RSGEA---DLGPARRGGEDSDHQSFLI-------- 215 + GRE+G A R G+ +G A R H ++ Sbjct: 460 KGPV---DVPGREDGKEAPEEAQLDRPGQGIAVPVGEAHRHEPPVPHDKVVVDEGQDREV 516 Query: 216 ----KVDGTGALDVSPHATGHQ------QEEELKKPDQDAIIQMI--VELLKRVGDQWEE 263 K A +P G E E ++P+Q + + + L+ GD E+ Sbjct: 517 PEENKPPSRHAGGKAPGVQGQMAPPLPDSEREKQEPEQGEVGKRPGQAQALEEAGDLPED 576 Query: 264 EQSLASQLGVALPNPA-----PAVRKKSQEKKTSLKRTSKTNPKKHGSEEAKRGAADVSS 318 Q + G PA P R + L + G E+AK G Sbjct: 577 PQKVPEADGQPAVQPAKEDLGPGDRGLHPRPQAVLSE-QQNGLAVGGGEKAKGGP----- 630 Query: 319 PEAWPPKKSSFLPLCVSGHRPSISSSYGLEEPKVQEAPSTEAGAPGPSVLPTPSESQEPG 378 PP ++ +P+ S +G + P E P APGP + P P E ++ Sbjct: 631 ----PPGNAAG-----DTGQPAEDSDHGGKPPLPAEKP-----APGPGLPPEPREQRDVE 676 Query: 379 EELPLDRASEYKEF----IQKIISMLQDAEEQQGEEQPQVQQEE---VGVENPAPHCRRK 431 AS+ +E + +LQ +EQQ +++ + Q+E +E ++ Sbjct: 677 RAGGNQAASQLEEAGRAEMLDHAVLLQVIKEQQVQQKRLLDQQEKLLAVIEEQHKEIHQQ 736 Query: 432 SQEKRSSFRRAFYHKKHTSKEPRRAGAAGAASPEARRPKRPSFLP-------LCVGGHRP 484 QE R + +EP A G +PE + + LP L G RP Sbjct: 737 RQEDEEDKPR----QVEVHQEPGAAVPRGQEAPEGKARETVENLPPLPLDPVLRAPGGRP 792 Query: 485 STSSSLDPEDLE------CREPL-PAEGEP-VVISEAPSQARGHTPEGAPQLSG 530 + S L+ LE R+P P +G P A ++ R + AP+ +G Sbjct: 793 APSQDLNQRSLEHSEGPVGRDPAGPPDGGPDTEPRAAQAKLRDGQKDAAPRAAG 846 >gi|153070256 MAGI family member, X-linked isoform d [Homo sapiens] Length = 253 Score = 43.1 bits (100), Expect = 8e-04 Identities = 65/273 (23%), Positives = 106/273 (38%), Gaps = 62/273 (22%) Query: 114 EPRERASRRPRGKEGISQHPEPLEAAGEPALRKKAHHDKKPSRKKQGHKKHAAEVTKAAQ 173 EPR + P+G G S+ P PL AG A + A D +P + AA V +A Sbjct: 2 EPRTGGAANPKGSRG-SRGPSPL--AGPSARQLLARLDARPLAARAAVDV-AALVRRAGA 57 Query: 174 DQEARGREEGLSKAAAALRSGEADLGPARRGGEDSDHQSFLIKVDGTGALDVSPHATGHQ 233 R +E A + L S + ++ +R PHAT Sbjct: 58 TLRLRRKE-----AVSVLDSADIEVTDSRL-----------------------PHAT--- 86 Query: 234 QEEELKKPDQDAIIQMIVELLKRVGDQWEEEQSLASQLGVALPNPAPAVRKKSQEKKTSL 293 IV+ +VGD ++Q G+ +R + + Sbjct: 87 ----------------IVDHRPQVGDLVLHINGESTQ-GLTHAQAVERIRAGGPQLHLVI 129 Query: 294 KRTSKTNP-KKHGSEEAKRG---AADVSSPEAWPPKKSSFLPLCVSGHRPSISSSYGLEE 349 +R +T+P K G E ++G + D PE + SS + H PS ++ L++ Sbjct: 130 RRPLETHPGKPRGVGEPRKGVDRSPDPGGPEVTGSRSSS---TSLVQHPPSRTT---LKK 183 Query: 350 PKVQEAPSTEAGAPGPSVLPTPSESQEPGEELP 382 + PS EA A GP+V P +++P +++P Sbjct: 184 TRGSPEPSPEAAADGPTVSPPERRAEDPNDQIP 216 >gi|153945728 microtubule-associated protein 1B [Homo sapiens] Length = 2468 Score = 42.7 bits (99), Expect = 0.001 Identities = 58/246 (23%), Positives = 101/246 (41%), Gaps = 45/246 (18%) Query: 264 EQSLASQLGVALPNPAPAVR----KKSQEKKTSLKRTSKTNPKKHGSEEAKRGAADVSSP 319 +Q LA+Q + P P V+ K+ + + SLK +K P K +E+K +V+ Sbjct: 512 KQPLATQKDLTGQVPTPVVKQTKLKQRADSRESLKPAAKPLPSKSVRKESKEETPEVTKV 571 Query: 320 E--AWPPKKSSFLPLCVSGHRPSISSSYGLEEPKV--QEAPSTEAGAP---------GPS 366 PPK S + V +P + + +P V +E PS E +P Sbjct: 572 NHVEKPPKVESKEKVMVKKDKPIKTET----KPSVTEKEVPSKEEPSPVKAEVAEKQATD 627 Query: 367 VLPTPSESQEPGEEL---PLDRASEYKEFIQKIISMLQDAEEQQGEEQPQVQQ------- 416 V P ++ + +E P D+ E KE +K ++ +D + EE+P+ ++ Sbjct: 628 VKPKAAKEKTVKKETKVKPEDKKEE-KEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKK 686 Query: 417 -----------EEVGVENPAPHCRR--KSQEKRSSFRRAFYHKKHTSKEPRRAGAAGAAS 463 +EV E P ++ K +EK+ + KK K P+ A + Sbjct: 687 EIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPL 746 Query: 464 PEARRP 469 EA++P Sbjct: 747 SEAKKP 752 Score = 30.4 bits (67), Expect = 5.3 Identities = 37/166 (22%), Positives = 64/166 (38%), Gaps = 13/166 (7%) Query: 218 DGTGALDVSPHATGHQQEEELKKPDQDAIIQMIVELLKRVGDQWEEEQSLASQLGVALPN 277 DG + VS ++EE K + DA I+ E + D+ EE+ A + G A + Sbjct: 957 DGEEHVCVSASKHSPTEDEESAKAEADAYIREKRESVASGDDRAEEDMDEAIEKGEAEQS 1016 Query: 278 PAPAVRKKSQEKKTSLKRTSKTNPKKHGSEEAKRGAADVSSPEAWPPKKSSFLPLCVSGH 337 A +E K R + P+K +E+ D ++ ++ FL Sbjct: 1017 EEEA----DEEDKAEDAREEEYEPEKMEAEDYVMAVVDKAAEAGGAEEQYGFL------- 1065 Query: 338 RPSISSSYGLEEPKVQEAPST-EAGAPGPSVLPTPSESQEPGEELP 382 + + G + P + A S + PG S + +E E+ P Sbjct: 1066 -TTPTKQLGAQSPGREPASSIHDETLPGGSESEATASDEENREDQP 1110 >gi|154816198 transcription elongation factor B polypeptide 3C-like [Homo sapiens] Length = 546 Score = 42.7 bits (99), Expect = 0.001 Identities = 42/142 (29%), Positives = 55/142 (38%), Gaps = 26/142 (18%) Query: 401 QDAEEQQGEEQPQVQQEEVGV-ENP-APHCRRKSQEKRSSFRRA-----FYHKKHTSKEP 453 + A Q+ E Q +++ G EN AP S E R + RR H + S+EP Sbjct: 92 ESASRQRFGEALQEREKAWGFPENATAPRSPSHSPEHRRTARRTPPGQQRPHPRSPSREP 151 Query: 454 RRAGAAGAASPEARRPKRPSFLPLCVGGHRPSTSSSLDPEDLECREPLPAEGEPVVISEA 513 R A R KRP P G HR DP P+P EP V E Sbjct: 152 R-----------AER-KRPRMAPADSGPHR-------DPPTRTAPLPMPEGPEPAVPGEQ 192 Query: 514 PSQARGHTPEGAPQLSGACESK 535 P + H +G P L C+ + Sbjct: 193 PGRGHAHAAQGGPLLGQGCQGQ 214 >gi|156938279 transcription elongation factor B polypeptide 3C [Homo sapiens] Length = 546 Score = 42.7 bits (99), Expect = 0.001 Identities = 42/142 (29%), Positives = 55/142 (38%), Gaps = 26/142 (18%) Query: 401 QDAEEQQGEEQPQVQQEEVGV-ENP-APHCRRKSQEKRSSFRRA-----FYHKKHTSKEP 453 + A Q+ E Q +++ G EN AP S E R + RR H + S+EP Sbjct: 92 ESASRQRFGEALQEREKAWGFPENATAPRSPSHSPEHRRTARRTPPGQQRPHPRSPSREP 151 Query: 454 RRAGAAGAASPEARRPKRPSFLPLCVGGHRPSTSSSLDPEDLECREPLPAEGEPVVISEA 513 R A R KRP P G HR DP P+P EP V E Sbjct: 152 R-----------AER-KRPRMAPADSGPHR-------DPPTRTAPLPMPEGPEPAVPGEQ 192 Query: 514 PSQARGHTPEGAPQLSGACESK 535 P + H +G P L C+ + Sbjct: 193 PGRGHAHAAQGGPLLGQGCQGQ 214 >gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens] Length = 2303 Score = 42.4 bits (98), Expect = 0.001 Identities = 64/271 (23%), Positives = 102/271 (37%), Gaps = 58/271 (21%) Query: 135 PLEAAGEPALRKKAHHDKKPSRKKQGHKKHAAEVTKAAQDQEARGREEGLSKAAAALRSG 194 P + G PA R++ +R+ GH+ A ++A+ + R G ++A L G Sbjct: 1415 PRDQPGGPAGRQRPTGRPTSARQAMGHRHKAGGAGRSAE----QSRGAGKNRAGLELPLG 1470 Query: 195 EADLGPARRGGEDSDHQSFLIKVDGTGALDVSPHATGHQQEEELKKPDQDAIIQMIVELL 254 PA + G + G GAL Q L P ++A+ Sbjct: 1471 RPPSAPADKDGSKPG------RTRGDGAL----------QSLCLTTPTEEAVYCF----- 1509 Query: 255 KRVGDQWEEEQSLASQLGVALPNPAPAVRKKSQEKKTSLKRTSKTNPKKHGSEEAKRGAA 314 G+ +EE PA ++TS + T + G +EA A Sbjct: 1510 --YGNDSDEE--------------PPAAAPTPTHRRTSAIPRAFTRERPQGRKEAP--AP 1551 Query: 315 DVSSPEAWPPKKSSFLPLCVSGHRPSI----SSSYGLEEPKVQEAPSTEAGAPGPSVLPT 370 ++P A PP ++ P ++ P SS+ L EP+ E P+ P+V Sbjct: 1552 SKAAPAAPPPARTQ--PSLIADETPPCYSLSSSASSLSEPEPSEPPAVHPRGREPAVTKD 1609 Query: 371 PSESQEPG---EELPLDRASEYKEFIQKIIS 398 P PG + P RA+E E +Q+ IS Sbjct: 1610 PG----PGGGRDSSPSPRAAE--ELLQRCIS 1634 >gi|118498345 AT-binding transcription factor 1 [Homo sapiens] Length = 3703 Score = 42.0 bits (97), Expect = 0.002 Identities = 53/222 (23%), Positives = 88/222 (39%), Gaps = 21/222 (9%) Query: 319 PEAWPPKKSSFLPLCVSGHRPSISSSYGLEEPKVQEAPSTEAGAPGPSVLPTPSESQEPG 378 P P S LP G PS +++ +P + PST +PG LPT +P Sbjct: 3123 PVLLPGLNSPSLP----GFTPS-NTALTSPKPNLMGLPSTTVPSPG---LPTSGLPNKPS 3174 Query: 379 EELPLDRASEYKEFIQKIISMLQDAEEQQGEEQPQVQQ---EEVGVENPAPHCRRKSQEK 435 +S + Q ++QQ ++QPQVQQ P P + Q++ Sbjct: 3175 SA---SLSSPTPAQATMAMGPQQPPQQQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQQ 3231 Query: 436 RSSFRRAFYHKKHTSKEPRRAGAAGAAS-PEARRPKRPSFLPLCVGGHRPSTSSSLDPED 494 R +K KE G P+ + + P+ + P+ ++DP Sbjct: 3232 RKDKD----SEKVKEKEKAHKGKGEPLPVPKKEKGEAPTATAATISAPLPTMEYAVDPAQ 3287 Query: 495 LEC-REPLPAEGEPVVISE-APSQARGHTPEGAPQLSGACES 534 L+ + L ++ ++ S+ P G +P APQ+ GA +S Sbjct: 3288 LQALQAALTSDPTALLTSQFLPYFVPGFSPYYAPQIPGALQS 3329 Score = 32.0 bits (71), Expect = 1.8 Identities = 40/166 (24%), Positives = 58/166 (34%), Gaps = 26/166 (15%) Query: 285 KSQEKKTSLKRTSKTNPKKHGSEEAKRGAADVSSP-----EAWPPKK------------- 326 K +EK K PKK E AA +S+P A P + Sbjct: 3241 KEKEKAHKGKGEPLPVPKKEKGEAPTATAATISAPLPTMEYAVDPAQLQALQAALTSDPT 3300 Query: 327 ----SSFLPLCVSGHRPSISSSY--GLEEPKVQEAPSTEAGAPGPSVLPTPSESQEPGEE 380 S FLP V G P + L+ +Q E P L PG Sbjct: 3301 ALLTSQFLPYFVPGFSPYYAPQIPGALQSGYLQPMYGMEGLFPYSPALSQALMGLSPGSL 3360 Query: 381 LPLDRASEYKEFIQKIISMLQDAEEQQGEEQPQVQQEEVGVENPAP 426 L + +Y++ +Q+ I Q + QQ ++Q QQ+ + P P Sbjct: 3361 L--QQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVP 3404 >gi|58331242 formin homology 2 domain containing 3 [Homo sapiens] Length = 1439 Score = 41.2 bits (95), Expect = 0.003 Identities = 68/287 (23%), Positives = 115/287 (40%), Gaps = 33/287 (11%) Query: 364 GPSVLPTPSESQEPGEELPLDRASE----YKEFIQKIISMLQDAEEQQGEEQPQVQQEEV 419 G SV TP+ S P +E L+R+S F Q S+ + E ++ E + ++Q+ E Sbjct: 416 GSSVPTTPTSSVSPPQEARLERSSPSGLLTSSFRQHQESLAAERERRRQEREERLQRIER 475 Query: 420 GVENPAPHC-------RRKSQEKRSSFRRAFYHKKHTSKEPRRAGAAGAA--SPEARRPK 470 N +R+++E+R + ++H + R+ + G A S + P Sbjct: 476 EERNKFSRDYLDKREEQRQAREERYKYLEQLAAEEHEKELRSRSVSRGRADLSLDLTSPA 535 Query: 471 RPSFL-PLCVGGHRPSTSSSLDPEDLEC------REPLPAEGEPVVISEAPSQARGH--- 520 P+ L PL H PS+S S + + P + G+P SEA +A Sbjct: 536 APACLAPL---SHSPSSSDSQEALTVSASSPGTPHHPQASAGDPEPESEAEPEAEAGAGQ 592 Query: 521 -TPEGAPQLSGACESKEIIIQKLVALLQEVDGQLGQQIRRHPSFKRFFYEFSDSPLSKLV 579 E ++ A E E +++ + E L ++ R++ S S +S Sbjct: 593 VADEAGQDIASAHEGAETEVEQALEQEPEERASLSEKERQNEGVNE-RDNCSASSVSSSS 651 Query: 580 ATLRSQVAHSSKLDRNRARRLYQFDVSLANKFAGSNSHAMCILMGLR 626 +TL + KL R+R L+ V + AG N IL R Sbjct: 652 STLERE-EKEDKLSRDRTTGLWPAGV----QDAGVNGQCGDILTNKR 693 >gi|21493022 A kinase (PRKA) anchor protein 12 isoform 1 [Homo sapiens] Length = 1782 Score = 41.2 bits (95), Expect = 0.003 Identities = 70/338 (20%), Positives = 118/338 (34%), Gaps = 71/338 (21%) Query: 209 DHQSFLIKVDGTGALDVSPHATGHQQEEELKKPDQDAIIQ------MIVELLKRVGDQWE 262 DH+ + + + P + + EE LK+ A I VE K G++ + Sbjct: 214 DHKDPSLGAGEAASKESEPKQSTEKPEETLKREQSHAEISPPAESGQAVEECKEEGEEKQ 273 Query: 263 EEQSLASQLGVALP--------------------NPAPAVRKKSQEKKTSLKRTSKTNPK 302 E++ S P + RK +++ + ++ + P+ Sbjct: 274 EKEPSKSAESPTSPVTSETGSTFKKFFTQGWAGWRKKTSFRKPKEDEVEASEKKKEQEPE 333 Query: 303 KHGSEEAKRGAADVSSPEAWPPKKSSFLPLCVSGHRPSISSSYGLEEPKVQEAPSTEAGA 362 K +EE G A+V+S + +++ S H P +S+ Y + E PS E Sbjct: 334 KVDTEED--GKAEVASEKLTASEQAHPQEPAESAHEPRLSAEY-----EKVELPSEEQ-- 384 Query: 363 PGPSVLPTPSESQEPGEELPLDRASEYKEFIQKIISMLQDAEEQQGEEQPQVQQEEVGVE 422 S SQ P EE P A+E F +KI +V QEEV E Sbjct: 385 --------VSGSQGPSEEKPAPLATEV--FDEKI----------------EVHQEEVVAE 418 Query: 423 NPAPHCRRKSQEKRSSFRRAFYHKKHTSKEPRRAGAAGAASPEARRPKRP--SFLPLCVG 480 +++E+++ P A P+ P + CV Sbjct: 419 VHVSTVEERTEEQKTEVEET------AGSVPAEELVEMDAEPQEAEPAKELVKLKETCVS 472 Query: 481 GHRPSTSSSLDPEDLECREPLPAEGEPVVISEAPSQAR 518 G P+ + L P++ + P EG + SQ R Sbjct: 473 GEDPTQGADLSPDEKVLSK--PPEGVVSEVEMLSSQER 508 Score = 31.6 bits (70), Expect = 2.4 Identities = 79/347 (22%), Positives = 128/347 (36%), Gaps = 45/347 (12%) Query: 197 DLGPARRGGEDSDHQSFLIKVDGTGALDVSPHATGHQQEEELKKPDQDAIIQMIVELLKR 256 D GP +DSD + ++ + A++ Q ++ ++P+Q A ++ EL Sbjct: 830 DAGPTGANEDDSDVPA-VVPLSEYDAVE-REKMEAQQAQKSAEQPEQKAATEVSKEL--- 884 Query: 257 VGDQWEEEQSLASQLGVALPNPAPAVRKKSQEKKTSLKRTSKTNPKKHGSEEAKRGAADV 316 E Q VA A + +E+ S S T P + EA +V Sbjct: 885 -----SESQVHMMAAAVADGTRAATI---IEERSPSWISASVTEPLEQVEAEAALLTEEV 936 Query: 317 SSPEAWPPKKSSFLPLCVSGHRPSISSSYGLEEPKVQEAPST-EAGAPGPSVLPTPSESQ 375 E ++ P V+ P + G + V EA T EA + P +E Sbjct: 937 LEREVIAEEE----PPTVTEPLPENREARG--DTVVSEAELTPEAVTAAETAGPLGAE-- 988 Query: 376 EPGEELPLDRASEYKEFIQKIISMLQDAEEQQGEEQPQVQQEEVGVENPAPHCRRKSQEK 435 E A E E + + S L D+ + E P VQ+ E GV + RR + Sbjct: 989 ---EGTEASAAEETTEMVSAV-SQLTDSPDTTEEATP-VQEVEGGVPDIEEQERRTQEVL 1043 Query: 436 RSSFRRAFYHKKHTSKEPRRAGAAGAASP----EARRPKRPSFLPLCVGGHRPSTSSSLD 491 ++ + K S+ P G P EA RP+ + G + T L Sbjct: 1044 QAVAEKV----KEESQLPGTGGPEDVLQPVQRAEAERPEEQAE----ASGLKKETDVVLK 1095 Query: 492 PEDLECREPLPAEGEPVVISEAPSQARGHTPEGAPQLSGACESKEII 538 + E A+ EP + Q + E APQ++ + ES E++ Sbjct: 1096 VDAQE------AKTEPFTQGKVVGQTTPESFEKAPQVTESIESSELV 1136 >gi|21493024 A kinase (PRKA) anchor protein 12 isoform 2 [Homo sapiens] Length = 1684 Score = 41.2 bits (95), Expect = 0.003 Identities = 70/338 (20%), Positives = 118/338 (34%), Gaps = 71/338 (21%) Query: 209 DHQSFLIKVDGTGALDVSPHATGHQQEEELKKPDQDAIIQ------MIVELLKRVGDQWE 262 DH+ + + + P + + EE LK+ A I VE K G++ + Sbjct: 116 DHKDPSLGAGEAASKESEPKQSTEKPEETLKREQSHAEISPPAESGQAVEECKEEGEEKQ 175 Query: 263 EEQSLASQLGVALP--------------------NPAPAVRKKSQEKKTSLKRTSKTNPK 302 E++ S P + RK +++ + ++ + P+ Sbjct: 176 EKEPSKSAESPTSPVTSETGSTFKKFFTQGWAGWRKKTSFRKPKEDEVEASEKKKEQEPE 235 Query: 303 KHGSEEAKRGAADVSSPEAWPPKKSSFLPLCVSGHRPSISSSYGLEEPKVQEAPSTEAGA 362 K +EE G A+V+S + +++ S H P +S+ Y + E PS E Sbjct: 236 KVDTEED--GKAEVASEKLTASEQAHPQEPAESAHEPRLSAEY-----EKVELPSEEQ-- 286 Query: 363 PGPSVLPTPSESQEPGEELPLDRASEYKEFIQKIISMLQDAEEQQGEEQPQVQQEEVGVE 422 S SQ P EE P A+E F +KI +V QEEV E Sbjct: 287 --------VSGSQGPSEEKPAPLATEV--FDEKI----------------EVHQEEVVAE 320 Query: 423 NPAPHCRRKSQEKRSSFRRAFYHKKHTSKEPRRAGAAGAASPEARRPKRP--SFLPLCVG 480 +++E+++ P A P+ P + CV Sbjct: 321 VHVSTVEERTEEQKTEVEET------AGSVPAEELVEMDAEPQEAEPAKELVKLKETCVS 374 Query: 481 GHRPSTSSSLDPEDLECREPLPAEGEPVVISEAPSQAR 518 G P+ + L P++ + P EG + SQ R Sbjct: 375 GEDPTQGADLSPDEKVLSK--PPEGVVSEVEMLSSQER 410 Score = 31.6 bits (70), Expect = 2.4 Identities = 79/347 (22%), Positives = 128/347 (36%), Gaps = 45/347 (12%) Query: 197 DLGPARRGGEDSDHQSFLIKVDGTGALDVSPHATGHQQEEELKKPDQDAIIQMIVELLKR 256 D GP +DSD + ++ + A++ Q ++ ++P+Q A ++ EL Sbjct: 732 DAGPTGANEDDSDVPA-VVPLSEYDAVE-REKMEAQQAQKSAEQPEQKAATEVSKEL--- 786 Query: 257 VGDQWEEEQSLASQLGVALPNPAPAVRKKSQEKKTSLKRTSKTNPKKHGSEEAKRGAADV 316 E Q VA A + +E+ S S T P + EA +V Sbjct: 787 -----SESQVHMMAAAVADGTRAATI---IEERSPSWISASVTEPLEQVEAEAALLTEEV 838 Query: 317 SSPEAWPPKKSSFLPLCVSGHRPSISSSYGLEEPKVQEAPST-EAGAPGPSVLPTPSESQ 375 E ++ P V+ P + G + V EA T EA + P +E Sbjct: 839 LEREVIAEEE----PPTVTEPLPENREARG--DTVVSEAELTPEAVTAAETAGPLGAE-- 890 Query: 376 EPGEELPLDRASEYKEFIQKIISMLQDAEEQQGEEQPQVQQEEVGVENPAPHCRRKSQEK 435 E A E E + + S L D+ + E P VQ+ E GV + RR + Sbjct: 891 ---EGTEASAAEETTEMVSAV-SQLTDSPDTTEEATP-VQEVEGGVPDIEEQERRTQEVL 945 Query: 436 RSSFRRAFYHKKHTSKEPRRAGAAGAASP----EARRPKRPSFLPLCVGGHRPSTSSSLD 491 ++ + K S+ P G P EA RP+ + G + T L Sbjct: 946 QAVAEKV----KEESQLPGTGGPEDVLQPVQRAEAERPEEQAE----ASGLKKETDVVLK 997 Query: 492 PEDLECREPLPAEGEPVVISEAPSQARGHTPEGAPQLSGACESKEII 538 + E A+ EP + Q + E APQ++ + ES E++ Sbjct: 998 VDAQE------AKTEPFTQGKVVGQTTPESFEKAPQVTESIESSELV 1038 >gi|11968023 zinc finger protein 106 homolog [Homo sapiens] Length = 1883 Score = 41.2 bits (95), Expect = 0.003 Identities = 62/278 (22%), Positives = 99/278 (35%), Gaps = 32/278 (11%) Query: 40 PTAPSRKALHWTTSDWARHSDSPAP-SAEAHCTTAAAPTPEETGDFLPSEQRP------- 91 PT ++K +H + + SDS A C TA P E T + +PS + P Sbjct: 401 PTQKTQKEIHTGSLNHKASSDSAASFEVVRQCPTAEKPEQEHTPNKMPSLKSPLLPCPAT 460 Query: 92 -----SQDTKKGWLKTMLNFFVRTGPEEPRERASRRPRGKEGISQHPEPLEAAGEPALRK 146 QD K T NFF P E ++ P K + + P + LR Sbjct: 461 KSLSQKQDPKNISKNTKTNFF------SPGEHSN--PSNKPTVEDNHGPYIS----KLRS 508 Query: 147 KAHHDKKPSRKKQGHKKHAAEVTK--AAQDQEARGREEGLSKAAAALRSGEADLGPARRG 204 H K ++ G +K + + + +E E L + + A R Sbjct: 509 SCPHVLKGNKSTFGSQKQSGDNLNDTLRKAKEVLQCHESLQNPLLSTSKSTRNYAKASRN 568 Query: 205 GEDSDHQSFLIKVDGTGALDVSPHATGHQQEEELKKPDQDAIIQMIVELLKRVGDQWEEE 264 E+S+ S I+ D S T ++ K + ++ R D+ EE+ Sbjct: 569 VEESEKGSLKIEFQVHALEDESDGETSDTEKHGTKIGTLGSATTELLSGSTRTADEKEED 628 Query: 265 QSLASQLGVALPNPA-PAVRKKSQEKKTSLKRTSKTNP 301 + +P P VR+K E L+ TS +P Sbjct: 629 DRILKTSRELSTSPCNPIVRQKESE----LQMTSAASP 662 Score = 31.2 bits (69), Expect = 3.1 Identities = 18/78 (23%), Positives = 39/78 (50%), Gaps = 10/78 (12%) Query: 373 ESQEPGEELPLDRASEYKEFIQKIISMLQDAEEQQGEEQPQVQQEEVGVENPAPHCRRKS 432 E GEE E F +++I +++ +EQ +++P +E+ ++ P RR+ Sbjct: 54 EDDGKGEE------EEEDYFDKELIQLIKQRKEQSRQDEPSNSNQEINSDDRRPQWRRED 107 Query: 433 ----QEKRSSFRRAFYHK 446 Q++ S + A++H+ Sbjct: 108 RIPYQDRESYSQPAWHHR 125 >gi|19923167 tubby isoform a [Homo sapiens] Length = 561 Score = 40.8 bits (94), Expect = 0.004 Identities = 70/336 (20%), Positives = 127/336 (37%), Gaps = 60/336 (17%) Query: 104 LNFFVRTGPEEPRERASRRPRGKEGISQHPEPLEAAGEPALRKKAHHDKKPSRKKQGHKK 163 ++FF TG P + P G + QH +P L++ D++ +R+K + K Sbjct: 12 VSFFAETGILFPG--GTPWPMGSQHSKQHRKP------GPLKRGHRRDRRTTRRK--YWK 61 Query: 164 HAAEVTKAAQDQEARGREEGLSKAAAALRSGEADLGPARRGGEDSDHQSFLIKVDGTGAL 223 E+ + D+ R++ L + A L + + + +++ + G Sbjct: 62 EGREIARVLDDEGRNLRQQKLDRQRALLEQKQ----------KKKRQEPLMVQANADGR- 110 Query: 224 DVSPHATGHQQEEELKKPDQDAIIQMIVELLKRVGDQWEEEQSLAS-QLGVALPNPAPAV 282 P + +Q EE Q +++ + Q +E SLAS QLG P APA Sbjct: 111 ---PRSRRARQSEE-----QAPLVESYLSSSGSTSYQVQEADSLASVQLGATRPT-APAS 161 Query: 283 RKKSQEKKTSLKRTSKTNPKKHGSEEAKRGAADVSSPEAWPPKKSSFLPLCVSGHRPSIS 342 K+++ T+ + +K G + G A ++ ++ L + S H Sbjct: 162 AKRTKAAATAGGQGGAARKEKKGKHKGTSGPAALAEDKSEAQGPVQILTVGQSDH----- 216 Query: 343 SSYGLEEPKVQEAPSTEAGAPGPSVLPTPSESQEPGEELPLDRASEYKEFIQKIISMLQD 402 Q+A T AG + G++L RA+ ++ I SM D Sbjct: 217 ---------AQDAGETAAG----------GGERPSGQDL---RATMQRKGISS--SMSFD 252 Query: 403 AEEQQGEEQPQVQQEEVGVENPAPHCRRKSQEKRSS 438 +E+ EE + P+ RKS + +S Sbjct: 253 EDEEDEEENSSSSSQLNSNTRPSSATSRKSVREAAS 288 >gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo sapiens] Length = 1158 Score = 40.8 bits (94), Expect = 0.004 Identities = 48/204 (23%), Positives = 73/204 (35%), Gaps = 26/204 (12%) Query: 279 APAVRKKSQEKKTSLKRTSKTNPKKHGSEEAKRGAADVSSPEAWPPKKSSFLPLCVSGHR 338 +P KK +EK + K P K + ++ P+ PPK + P SG R Sbjct: 113 SPRPPKKGKEKPPKATKKPKEKPPKATKKPKEKPPKATKKPKEKPPKATKKPP---SGKR 169 Query: 339 PSISSSYGLEEPKVQEAPSTEAGAPGPSVLPTPSES------QEPGEELPLDRASEYKEF 392 P I L + E P +PGP LP + Q PGEE ++ E Sbjct: 170 PPI-----LAPSETLEWPLPPPPSPGPEELPQEGGAPLSNNWQNPGEETHVEAREHQPE- 223 Query: 393 IQKIISMLQDAEEQQGEEQPQVQQEEVGVENPAPHCRRKSQEKRSSFRRAFYHKKHTSKE 452 ++ E+ + Q+++E+ + RR+ Q + RR + E Sbjct: 224 ------PEEETEQPTLDYNDQIEREDY---EDFEYIRRQKQPRPPPSRRR--RPERVWPE 272 Query: 453 PRRAGAAGAASPEARRPKRPSFLP 476 P A A E P LP Sbjct: 273 PPEEKAPAPAPEERIEPPVKPLLP 296 >gi|50428935 BPY2 interacting protein 1 [Homo sapiens] Length = 1059 Score = 40.8 bits (94), Expect = 0.004 Identities = 76/320 (23%), Positives = 106/320 (33%), Gaps = 62/320 (19%) Query: 272 GVALPNPAPAVRKKSQEKKTSLKRTSKTNPKKHGS----EEAKRGAADVSS--------- 318 GVA PA A + EK+ R K +PK S E +R A+ V + Sbjct: 500 GVARKEPARAEAPRKTEKEAKTPRELKKDPKPSVSRTQPREVRRAASSVPNLKKTNAQAA 559 Query: 319 --PEAWPPKKSSFLPLCVSGHRPSISSSYGLEEPKVQEAPSTEAGAPGPSVLPTPS---- 372 P P S P +G R S G P PS G+P ++ TPS Sbjct: 560 PKPRKAPSTSHSGFPPVANGPRSPPSLRCGEASP-----PSAACGSPASQLVATPSLELG 614 Query: 373 ---ESQEPGEELPLDRASEYKEFIQKIISMLQDAEEQQ---------GE---------EQ 411 +E ELPL +S + S AE + GE Sbjct: 615 PIPAGEEKALELPLAASSIPRPRTPSPESHRSPAEGSERLSLSPLRGGEAGPDASPTVTT 674 Query: 412 PQVQQEEVGVENPAPHCRRKSQEKRSSFRRAFYHKKHTSKEPRRAGAAGAASPEARRPKR 471 P V + E +PH + SF + TS+ G P ARR Sbjct: 675 PTVTTPSLPAEVGSPHSTEVDESLSVSFEQVLPPSAPTSEAGLSLPLRG---PRARRSAS 731 Query: 472 PSFLPLCVGGHRPSTSSSLDPEDLECREPLPAEGEPVVI-SEAPSQARGHTPEGAPQLSG 530 P + LC+ + P + E R+ +P P S S AR G G Sbjct: 732 PHDVDLCL----------VSPCEFEHRKAVPMAPAPASPGSSNDSSARSQERAGG---LG 778 Query: 531 ACESKEIIIQKLVALLQEVD 550 A E+ + + + L + D Sbjct: 779 AEETPPTSVSESLPTLSDSD 798 >gi|151301137 AT-hook transcription factor [Homo sapiens] Length = 1439 Score = 40.4 bits (93), Expect = 0.005 Identities = 110/534 (20%), Positives = 186/534 (34%), Gaps = 93/534 (17%) Query: 11 LAEKKARSLDRPQAPGKGSESWDCHWLSLPTAPSRKALHWTTSDWARHSDSPAPSAEAHC 70 L E ++ P+ PG S +L + P+ LH T A +P P+ + C Sbjct: 655 LKEHIDQTQQEPEPPGSDS--------ALDSTPALPCLHQPTHLPAPSGQAPMPAIKTSC 706 Query: 71 -----TTAAAPT---------------------PEETGDFLPSEQRPSQDTKKGWLKTML 104 TTAAA T P++ L ++ + G ++ L Sbjct: 707 PEPATTTAAASTGPCPLHVNVEVSSGNSEVEDRPQDPLARLRHKELQMEQVYHGLMERYL 766 Query: 105 NFFVRTGPEEPRERASRRPRGKEGISQHPEPLEAAGEPALRKKAHHDKKPSRK--KQGHK 162 + V++ PE R +E + LE G A KA + R+ Q K Sbjct: 767 S--VKSLPEAMRMEEEEEGEEEEEEEGGGDSLEVDGVAATPGKAEATRVLPRQCPVQAEK 824 Query: 163 KHAA---EVTKAAQDQEARGREEGLSKAAAALRSGEADLGPARRG--------GEDSDHQ 211 H A E T+ + G + L++ G+A+ P G + HQ Sbjct: 825 SHGAPLEEATEKMVSMKPPGFQASLARDGHMSGLGKAEAAPPGPGVPPHPPGTKSAASHQ 884 Query: 212 SFLIKVDGTGALDVSP----HATG--HQQEEELKKPDQDAIIQMIVELLKRVGDQWEEEQ 265 S + ++G+G + P H G H +E + P+ D+ + RV + + Sbjct: 885 SSMTSLEGSGISERLPQKPLHRGGGPHLEETWMASPETDS--GFVGSETSRVSPLTQTPE 942 Query: 266 SLASQLGVALPNPAPAVRKKSQEKKTSLKRTSKTNPKKHGSEEAKRGAADVSSPEAWPPK 325 S + A +Q S+ R + PK GS +R A + S+P + + Sbjct: 943 HRLSHISTA--------GTLAQPFAASVPRDGASYPKARGSLIPRR-ATEPSTPRSQAQR 993 Query: 326 --KSSFLPLCVSGHRPSISSSYGLE----------EPKVQEAP-----STEAGAPGPSVL 368 S PL S+ + E ++ E P + AP P+ Sbjct: 994 YLSSPSGPLRQRAPNFSLERTLAAEMAVPGSEFEGHKRISEQPLPNKTISPPPAPAPAAA 1053 Query: 369 PTPSESQEPGEELPLDRAS------EYKEFIQKIISMLQDAEEQQGEEQPQVQQEEVGVE 422 P P E L RA E +E + ++ L+D+ Q + P + + Sbjct: 1054 PLPCGPTETIPSFLLTRAGRDQAICELQEEVSRLRLRLEDSLHQPLQGSP--TRPASAFD 1111 Query: 423 NPAPHCRRKSQEKRSSFRRAFYHKKHTSKEPRRAGAAGAASPEARRPKRPSFLP 476 PA R + + +++ + Y K T + P P R+ R S +P Sbjct: 1112 RPA-RTRGRPADSPATW-GSHYGSKSTERLPGEPRGEEQIVPPGRQRARSSSVP 1163 >gi|29789008 Huntingtin interacting protein C isoform 2 [Homo sapiens] Length = 858 Score = 40.4 bits (93), Expect = 0.005 Identities = 26/97 (26%), Positives = 38/97 (39%), Gaps = 3/97 (3%) Query: 347 LEEPKVQEAPSTEAGAPGPSVLPTPSESQEPGEELPLDRASEYKEFIQKIISMLQDAEEQ 406 L+ Q P PGP+ +PT EPG D + Q + L++ Sbjct: 184 LQPQPPQPQPDPPPVPPGPTPVPTGLLEPEPGGSEDCDVLEATQPLEQGFLQQLEEGPSS 243 Query: 407 QGEEQPQVQQEEVGVENPAPHCRRKSQEKRSSFRRAF 443 G+ QPQ ++EE P P S R ++AF Sbjct: 244 SGQHQPQQEEEE---SKPEPERSGLSWSNREKAKQAF 277 >gi|72534686 Huntingtin interacting protein C isoform 1 [Homo sapiens] Length = 871 Score = 40.4 bits (93), Expect = 0.005 Identities = 26/97 (26%), Positives = 38/97 (39%), Gaps = 3/97 (3%) Query: 347 LEEPKVQEAPSTEAGAPGPSVLPTPSESQEPGEELPLDRASEYKEFIQKIISMLQDAEEQ 406 L+ Q P PGP+ +PT EPG D + Q + L++ Sbjct: 190 LQPQPPQPQPDPPPVPPGPTPVPTGLLEPEPGGSEDCDVLEATQPLEQGFLQQLEEGPSS 249 Query: 407 QGEEQPQVQQEEVGVENPAPHCRRKSQEKRSSFRRAF 443 G+ QPQ ++EE P P S R ++AF Sbjct: 250 SGQHQPQQEEEE---SKPEPERSGLSWSNREKAKQAF 283 >gi|38201621 eukaryotic translation initiation factor 4 gamma, 1 isoform 1 [Homo sapiens] Length = 1599 Score = 39.7 bits (91), Expect = 0.009 Identities = 64/282 (22%), Positives = 103/282 (36%), Gaps = 40/282 (14%) Query: 279 APAVRKKSQEKKTSLKRTSKT----NPKKHG---SEEAKRGAADVSSPEAWPPKKSSFLP 331 APA +Q + + KR KT +P + G +EE GA S+P PP+ L Sbjct: 159 APAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPT--PPQTGGGLE 216 Query: 332 LCVSGHRPSISSSYGLEEPKVQEAPSTEAGAPGP------------SVLPTPSESQEPGE 379 +G P ++ ++ + G PGP S P+PS EPG Sbjct: 217 PQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGS 276 Query: 380 E-------LPLDRASEYKEFIQKIISMLQDAEEQ---QGEEQP---QVQQEEVGVENPAP 426 E +P D + + +++ + ++ E E P + + EV + P P Sbjct: 277 EPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVP 336 Query: 427 HCRRKSQEKRSSFRRAFYHKKHTSK--EPRRAGAAGAASPEARRPKRPSFLPLCVGGHRP 484 +S+ S + HT + EP + PE + P C Sbjct: 337 ----ESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPV 392 Query: 485 STSSSLDPEDLECREPLPAEGEPVVISEAPSQARGHTPEGAP 526 + + PE+L P P + +SE QA+ T AP Sbjct: 393 PIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAP 434 >gi|38201627 eukaryotic translation initiation factor 4 gamma, 1 isoform 2 [Homo sapiens] Length = 1512 Score = 39.7 bits (91), Expect = 0.009 Identities = 64/282 (22%), Positives = 103/282 (36%), Gaps = 40/282 (14%) Query: 279 APAVRKKSQEKKTSLKRTSKT----NPKKHG---SEEAKRGAADVSSPEAWPPKKSSFLP 331 APA +Q + + KR KT +P + G +EE GA S+P PP+ L Sbjct: 72 APAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPT--PPQTGGGLE 129 Query: 332 LCVSGHRPSISSSYGLEEPKVQEAPSTEAGAPGP------------SVLPTPSESQEPGE 379 +G P ++ ++ + G PGP S P+PS EPG Sbjct: 130 PQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGS 189 Query: 380 E-------LPLDRASEYKEFIQKIISMLQDAEEQ---QGEEQP---QVQQEEVGVENPAP 426 E +P D + + +++ + ++ E E P + + EV + P P Sbjct: 190 EPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVP 249 Query: 427 HCRRKSQEKRSSFRRAFYHKKHTSK--EPRRAGAAGAASPEARRPKRPSFLPLCVGGHRP 484 +S+ S + HT + EP + PE + P C Sbjct: 250 ----ESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPV 305 Query: 485 STSSSLDPEDLECREPLPAEGEPVVISEAPSQARGHTPEGAP 526 + + PE+L P P + +SE QA+ T AP Sbjct: 306 PIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAP 347 >gi|38201623 eukaryotic translation initiation factor 4 gamma, 1 isoform 1 [Homo sapiens] Length = 1599 Score = 39.7 bits (91), Expect = 0.009 Identities = 64/282 (22%), Positives = 103/282 (36%), Gaps = 40/282 (14%) Query: 279 APAVRKKSQEKKTSLKRTSKT----NPKKHG---SEEAKRGAADVSSPEAWPPKKSSFLP 331 APA +Q + + KR KT +P + G +EE GA S+P PP+ L Sbjct: 159 APAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPT--PPQTGGGLE 216 Query: 332 LCVSGHRPSISSSYGLEEPKVQEAPSTEAGAPGP------------SVLPTPSESQEPGE 379 +G P ++ ++ + G PGP S P+PS EPG Sbjct: 217 PQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGS 276 Query: 380 E-------LPLDRASEYKEFIQKIISMLQDAEEQ---QGEEQP---QVQQEEVGVENPAP 426 E +P D + + +++ + ++ E E P + + EV + P P Sbjct: 277 EPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVP 336 Query: 427 HCRRKSQEKRSSFRRAFYHKKHTSK--EPRRAGAAGAASPEARRPKRPSFLPLCVGGHRP 484 +S+ S + HT + EP + PE + P C Sbjct: 337 ----ESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPV 392 Query: 485 STSSSLDPEDLECREPLPAEGEPVVISEAPSQARGHTPEGAP 526 + + PE+L P P + +SE QA+ T AP Sbjct: 393 PIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAP 434 >gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3 [Homo sapiens] Length = 2004 Score = 39.7 bits (91), Expect = 0.009 Identities = 85/421 (20%), Positives = 143/421 (33%), Gaps = 92/421 (21%) Query: 79 EETGDFLPSEQRPSQDTKKGWLKTMLNFFV-------RTGPE-------EPRERASRR-P 123 E + SE++PSQD K K L+ V + PE E ER RR Sbjct: 915 ESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCRLTEGSERLPRRYS 974 Query: 124 RGKEGI----------SQHPEPLEAAGEPALRKKAHHDKKP----SRKKQGHKKHAAEVT 169 G + + PE ++ P L K KKP R+ + K H + V Sbjct: 975 EGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRRRRVRKRKHHNSSVV 1034 Query: 170 KAAQDQEARGREEGLSKAAAALRSGEADLGPARRGGEDSDHQSFLIKVDGTGALDVSPHA 229 + +E EDSD + + +++ T +D Sbjct: 1035 TETISETTEVLDEPF---------------------EDSDSERPMPRLEPTFEIDEEEEE 1073 Query: 230 TGHQQ---EEELKKPDQDAIIQMIVELLKRVGDQWEEEQSLASQLGVALPNPAPAVRKKS 286 + E ++ +++ ++ D+ E+E+S + + P +RK+ Sbjct: 1074 EDENELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDAD-DTPILKPVSLLRKRD 1132 Query: 287 QEKKTSLKRTSKTNPKKHGSEEAKRGAADVSSPEAW---PPKKSSF------LPLCVSGH 337 + TS KK G + K P W P +K F +P+ Sbjct: 1133 VKNSPLEPDTSTPLKKKKGWPKGKS-----RKPIHWKKRPGRKPGFKLSREIMPVSTQAC 1187 Query: 338 --RPSISSSYGLEEPKVQEAPSTEAGAPGPSVLPTPSESQEPGEELPLDRASEYKEFIQK 395 P +S +PK+QE+ E+ EP E++PL + +E +Q Sbjct: 1188 VIEPIVSIPKAGRKPKIQES----------------EETVEPKEDMPLPEERKEEEEMQA 1231 Query: 396 IISMLQDAEEQQGEEQPQVQQEEVGVENPAPHCRRKSQEKRSSFRRAFYHKKHTSKEPRR 455 +AEE + E+ EV +PA E + K S+E R+ Sbjct: 1232 ------EAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQ 1285 Query: 456 A 456 + Sbjct: 1286 S 1286 >gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3 [Homo sapiens] Length = 2004 Score = 39.7 bits (91), Expect = 0.009 Identities = 85/421 (20%), Positives = 143/421 (33%), Gaps = 92/421 (21%) Query: 79 EETGDFLPSEQRPSQDTKKGWLKTMLNFFV-------RTGPE-------EPRERASRR-P 123 E + SE++PSQD K K L+ V + PE E ER RR Sbjct: 915 ESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCRLTEGSERLPRRYS 974 Query: 124 RGKEGI----------SQHPEPLEAAGEPALRKKAHHDKKP----SRKKQGHKKHAAEVT 169 G + + PE ++ P L K KKP R+ + K H + V Sbjct: 975 EGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRRRRVRKRKHHNSSVV 1034 Query: 170 KAAQDQEARGREEGLSKAAAALRSGEADLGPARRGGEDSDHQSFLIKVDGTGALDVSPHA 229 + +E EDSD + + +++ T +D Sbjct: 1035 TETISETTEVLDEPF---------------------EDSDSERPMPRLEPTFEIDEEEEE 1073 Query: 230 TGHQQ---EEELKKPDQDAIIQMIVELLKRVGDQWEEEQSLASQLGVALPNPAPAVRKKS 286 + E ++ +++ ++ D+ E+E+S + + P +RK+ Sbjct: 1074 EDENELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDAD-DTPILKPVSLLRKRD 1132 Query: 287 QEKKTSLKRTSKTNPKKHGSEEAKRGAADVSSPEAW---PPKKSSF------LPLCVSGH 337 + TS KK G + K P W P +K F +P+ Sbjct: 1133 VKNSPLEPDTSTPLKKKKGWPKGKS-----RKPIHWKKRPGRKPGFKLSREIMPVSTQAC 1187 Query: 338 --RPSISSSYGLEEPKVQEAPSTEAGAPGPSVLPTPSESQEPGEELPLDRASEYKEFIQK 395 P +S +PK+QE+ E+ EP E++PL + +E +Q Sbjct: 1188 VIEPIVSIPKAGRKPKIQES----------------EETVEPKEDMPLPEERKEEEEMQA 1231 Query: 396 IISMLQDAEEQQGEEQPQVQQEEVGVENPAPHCRRKSQEKRSSFRRAFYHKKHTSKEPRR 455 +AEE + E+ EV +PA E + K S+E R+ Sbjct: 1232 ------EAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQ 1285 Query: 456 A 456 + Sbjct: 1286 S 1286 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.310 0.127 0.374 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 30,399,787 Number of Sequences: 37866 Number of extensions: 1740970 Number of successful extensions: 9954 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 46 Number of HSP's successfully gapped in prelim test: 477 Number of HSP's that attempted gapping in prelim test: 8803 Number of HSP's gapped (non-prelim): 1498 length of query: 652 length of database: 18,247,518 effective HSP length: 109 effective length of query: 543 effective length of database: 14,120,124 effective search space: 7667227332 effective search space used: 7667227332 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.