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Search of human proteins with 65506769
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|65506769 neurotrophic tyrosine kinase, receptor, type 2
isoform d precursor [Homo sapiens]
(553 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|65506769 neurotrophic tyrosine kinase, receptor, type 2 isofo... 1154 0.0
gi|21361306 neurotrophic tyrosine kinase, receptor, type 2 isofo... 1134 0.0
gi|65506779 neurotrophic tyrosine kinase, receptor, type 2 isofo... 1110 0.0
gi|65506745 neurotrophic tyrosine kinase, receptor, type 2 isofo... 1089 0.0
gi|55956790 neurotrophic tyrosine kinase, receptor, type 2 isofo... 975 0.0
gi|55956794 neurotrophic tyrosine kinase, receptor, type 3 isofo... 356 4e-98
gi|59889562 neurotrophic tyrosine kinase, receptor, type 3 isofo... 352 4e-97
gi|59889560 neurotrophic tyrosine kinase, receptor, type 3 isofo... 352 4e-97
gi|59889558 neurotrophic tyrosine kinase, receptor, type 1 isofo... 247 2e-65
gi|4585712 neurotrophic tyrosine kinase, receptor, type 1 isofor... 247 2e-65
gi|56118210 neurotrophic tyrosine kinase, receptor, type 1 isofo... 235 7e-62
gi|94420689 neural cell adhesion molecule 1 isoform 1 [Homo sapi... 80 6e-15
gi|115529478 neural cell adhesion molecule 1 isoform 3 [Homo sap... 80 6e-15
gi|115529482 neural cell adhesion molecule 1 isoform 2 [Homo sap... 76 9e-14
gi|118572606 hemicentin 1 [Homo sapiens] 75 1e-13
gi|126517478 peroxidasin homolog-like [Homo sapiens] 73 6e-13
gi|42544233 leucine rich repeat neuronal 2 [Homo sapiens] 72 2e-12
gi|42544231 leucine rich repeat neuronal 2 [Homo sapiens] 72 2e-12
gi|41582239 immunoglobulin superfamily containing leucine-rich r... 70 5e-12
gi|5031809 immunoglobulin superfamily containing leucine-rich re... 70 5e-12
gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens] 69 1e-11
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 69 1e-11
gi|239743951 PREDICTED: hypothetical protein XP_002342997 [Homo ... 69 1e-11
gi|7662320 leucine-rich repeats and immunoglobulin-like domains ... 67 3e-11
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 67 4e-11
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 67 4e-11
gi|153791507 leucine rich repeat neuronal 3 [Homo sapiens] 66 7e-11
gi|153792651 leucine rich repeat neuronal 3 [Homo sapiens] 66 7e-11
gi|153792227 leucine rich repeat neuronal 3 [Homo sapiens] 66 7e-11
gi|109150416 peroxidasin [Homo sapiens] 64 3e-10
>gi|65506769 neurotrophic tyrosine kinase, receptor, type 2 isoform
d precursor [Homo sapiens]
Length = 553
Score = 1154 bits (2986), Expect = 0.0
Identities = 553/553 (100%), Positives = 553/553 (100%)
Query: 1 MSSWIRWHGPAMARLWGFCWLVVGFWRAAFACPTSCKCSASRIWCSDPSPGIVAFPRLEP 60
MSSWIRWHGPAMARLWGFCWLVVGFWRAAFACPTSCKCSASRIWCSDPSPGIVAFPRLEP
Sbjct: 1 MSSWIRWHGPAMARLWGFCWLVVGFWRAAFACPTSCKCSASRIWCSDPSPGIVAFPRLEP 60
Query: 61 NSVDPENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAFLKNSNLQHI 120
NSVDPENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAFLKNSNLQHI
Sbjct: 61 NSVDPENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAFLKNSNLQHI 120
Query: 121 NFTRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLNES 180
NFTRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLNES
Sbjct: 121 NFTRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLNES 180
Query: 181 SKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHM 240
SKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHM
Sbjct: 181 SKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHM 240
Query: 241 NETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHH 300
NETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHH
Sbjct: 241 NETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHH 300
Query: 301 WCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYT 360
WCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYT
Sbjct: 301 WCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYT 360
Query: 361 LIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYEDYGTAANDIGDTTNRSNEIPST 420
LIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYEDYGTAANDIGDTTNRSNEIPST
Sbjct: 361 LIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYEDYGTAANDIGDTTNRSNEIPST 420
Query: 421 DVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLLKLARHSKFGMKDFSWFGFGKVKSRQG 480
DVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLLKLARHSKFGMKDFSWFGFGKVKSRQG
Sbjct: 421 DVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLLKLARHSKFGMKDFSWFGFGKVKSRQG 480
Query: 481 VGPASVISNDDDSASPLHHISNGSNTPSSSEGGPDAVIIGMTKIPVIENPQYFGITNSQL 540
VGPASVISNDDDSASPLHHISNGSNTPSSSEGGPDAVIIGMTKIPVIENPQYFGITNSQL
Sbjct: 481 VGPASVISNDDDSASPLHHISNGSNTPSSSEGGPDAVIIGMTKIPVIENPQYFGITNSQL 540
Query: 541 KPDTWPRGSPKTA 553
KPDTWPRGSPKTA
Sbjct: 541 KPDTWPRGSPKTA 553
>gi|21361306 neurotrophic tyrosine kinase, receptor, type 2 isoform
a precursor [Homo sapiens]
Length = 838
Score = 1134 bits (2933), Expect = 0.0
Identities = 544/545 (99%), Positives = 545/545 (100%)
Query: 1 MSSWIRWHGPAMARLWGFCWLVVGFWRAAFACPTSCKCSASRIWCSDPSPGIVAFPRLEP 60
MSSWIRWHGPAMARLWGFCWLVVGFWRAAFACPTSCKCSASRIWCSDPSPGIVAFPRLEP
Sbjct: 1 MSSWIRWHGPAMARLWGFCWLVVGFWRAAFACPTSCKCSASRIWCSDPSPGIVAFPRLEP 60
Query: 61 NSVDPENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAFLKNSNLQHI 120
NSVDPENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAFLKNSNLQHI
Sbjct: 61 NSVDPENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAFLKNSNLQHI 120
Query: 121 NFTRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLNES 180
NFTRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLNES
Sbjct: 121 NFTRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLNES 180
Query: 181 SKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHM 240
SKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHM
Sbjct: 181 SKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHM 240
Query: 241 NETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHH 300
NETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHH
Sbjct: 241 NETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHH 300
Query: 301 WCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYT 360
WCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYT
Sbjct: 301 WCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYT 360
Query: 361 LIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYEDYGTAANDIGDTTNRSNEIPST 420
LIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYEDYGTAANDIGDTTNRSNEIPST
Sbjct: 361 LIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYEDYGTAANDIGDTTNRSNEIPST 420
Query: 421 DVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLLKLARHSKFGMKDFSWFGFGKVKSRQG 480
DVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLLKLARHSKFGMKDFSWFGFGKVKSRQG
Sbjct: 421 DVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLLKLARHSKFGMKDFSWFGFGKVKSRQG 480
Query: 481 VGPASVISNDDDSASPLHHISNGSNTPSSSEGGPDAVIIGMTKIPVIENPQYFGITNSQL 540
VGPASVISNDDDSASPLHHISNGSNTPSSSEGGPDAVIIGMTKIPVIENPQYFGITNSQL
Sbjct: 481 VGPASVISNDDDSASPLHHISNGSNTPSSSEGGPDAVIIGMTKIPVIENPQYFGITNSQL 540
Query: 541 KPDTW 545
KPDT+
Sbjct: 541 KPDTF 545
>gi|65506779 neurotrophic tyrosine kinase, receptor, type 2 isoform
e precursor [Homo sapiens]
Length = 537
Score = 1110 bits (2870), Expect = 0.0
Identities = 537/553 (97%), Positives = 537/553 (97%), Gaps = 16/553 (2%)
Query: 1 MSSWIRWHGPAMARLWGFCWLVVGFWRAAFACPTSCKCSASRIWCSDPSPGIVAFPRLEP 60
MSSWIRWHGPAMARLWGFCWLVVGFWRAAFACPTSCKCSASRIWCSDPSPGIVAFPRLEP
Sbjct: 1 MSSWIRWHGPAMARLWGFCWLVVGFWRAAFACPTSCKCSASRIWCSDPSPGIVAFPRLEP 60
Query: 61 NSVDPENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAFLKNSNLQHI 120
NSVDPENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAFLKNSNLQHI
Sbjct: 61 NSVDPENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAFLKNSNLQHI 120
Query: 121 NFTRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLNES 180
NFTRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLNES
Sbjct: 121 NFTRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLNES 180
Query: 181 SKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHM 240
SKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHM
Sbjct: 181 SKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHM 240
Query: 241 NETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHH 300
NETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHH
Sbjct: 241 NETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHH 300
Query: 301 WCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYT 360
WCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYT
Sbjct: 301 WCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYT 360
Query: 361 LIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYEDYGTAANDIGDTTNRSNEIPST 420
LIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYEDYGTAANDIGDTTNRSNEIPST
Sbjct: 361 LIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYEDYGTAANDIGDTTNRSNEIPST 420
Query: 421 DVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLLKLARHSKFGMKDFSWFGFGKVKSRQG 480
DVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLLKLARHSKFGMK
Sbjct: 421 DVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLLKLARHSKFGMK--------------- 465
Query: 481 VGPASVISNDDDSASPLHHISNGSNTPSSSEGGPDAVIIGMTKIPVIENPQYFGITNSQL 540
GPASVISNDDDSASPLHHISNGSNTPSSSEGGPDAVIIGMTKIPVIENPQYFGITNSQL
Sbjct: 466 -GPASVISNDDDSASPLHHISNGSNTPSSSEGGPDAVIIGMTKIPVIENPQYFGITNSQL 524
Query: 541 KPDTWPRGSPKTA 553
KPDTWPRGSPKTA
Sbjct: 525 KPDTWPRGSPKTA 537
>gi|65506745 neurotrophic tyrosine kinase, receptor, type 2 isoform
c precursor [Homo sapiens]
Length = 822
Score = 1089 bits (2817), Expect = 0.0
Identities = 528/545 (96%), Positives = 529/545 (97%), Gaps = 16/545 (2%)
Query: 1 MSSWIRWHGPAMARLWGFCWLVVGFWRAAFACPTSCKCSASRIWCSDPSPGIVAFPRLEP 60
MSSWIRWHGPAMARLWGFCWLVVGFWRAAFACPTSCKCSASRIWCSDPSPGIVAFPRLEP
Sbjct: 1 MSSWIRWHGPAMARLWGFCWLVVGFWRAAFACPTSCKCSASRIWCSDPSPGIVAFPRLEP 60
Query: 61 NSVDPENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAFLKNSNLQHI 120
NSVDPENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAFLKNSNLQHI
Sbjct: 61 NSVDPENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAFLKNSNLQHI 120
Query: 121 NFTRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLNES 180
NFTRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLNES
Sbjct: 121 NFTRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLNES 180
Query: 181 SKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHM 240
SKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHM
Sbjct: 181 SKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHM 240
Query: 241 NETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHH 300
NETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHH
Sbjct: 241 NETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHH 300
Query: 301 WCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYT 360
WCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYT
Sbjct: 301 WCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYT 360
Query: 361 LIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYEDYGTAANDIGDTTNRSNEIPST 420
LIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYEDYGTAANDIGDTTNRSNEIPST
Sbjct: 361 LIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYEDYGTAANDIGDTTNRSNEIPST 420
Query: 421 DVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLLKLARHSKFGMKDFSWFGFGKVKSRQG 480
DVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLLKLARHSKFGMK
Sbjct: 421 DVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLLKLARHSKFGMK--------------- 465
Query: 481 VGPASVISNDDDSASPLHHISNGSNTPSSSEGGPDAVIIGMTKIPVIENPQYFGITNSQL 540
GPASVISNDDDSASPLHHISNGSNTPSSSEGGPDAVIIGMTKIPVIENPQYFGITNSQL
Sbjct: 466 -GPASVISNDDDSASPLHHISNGSNTPSSSEGGPDAVIIGMTKIPVIENPQYFGITNSQL 524
Query: 541 KPDTW 545
KPDT+
Sbjct: 525 KPDTF 529
>gi|55956790 neurotrophic tyrosine kinase, receptor, type 2 isoform
b precursor [Homo sapiens]
Length = 477
Score = 975 bits (2521), Expect = 0.0
Identities = 467/470 (99%), Positives = 467/470 (99%)
Query: 1 MSSWIRWHGPAMARLWGFCWLVVGFWRAAFACPTSCKCSASRIWCSDPSPGIVAFPRLEP 60
MSSWIRWHGPAMARLWGFCWLVVGFWRAAFACPTSCKCSASRIWCSDPSPGIVAFPRLEP
Sbjct: 1 MSSWIRWHGPAMARLWGFCWLVVGFWRAAFACPTSCKCSASRIWCSDPSPGIVAFPRLEP 60
Query: 61 NSVDPENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAFLKNSNLQHI 120
NSVDPENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAFLKNSNLQHI
Sbjct: 61 NSVDPENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAFLKNSNLQHI 120
Query: 121 NFTRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLNES 180
NFTRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLNES
Sbjct: 121 NFTRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLNES 180
Query: 181 SKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHM 240
SKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHM
Sbjct: 181 SKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHM 240
Query: 241 NETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHH 300
NETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHH
Sbjct: 241 NETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHH 300
Query: 301 WCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYT 360
WCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYT
Sbjct: 301 WCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYT 360
Query: 361 LIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYEDYGTAANDIGDTTNRSNEIPST 420
LIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYEDYGTAANDIGDTTNRSNEIPST
Sbjct: 361 LIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYEDYGTAANDIGDTTNRSNEIPST 420
Query: 421 DVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLLKLARHSKFGMKDFSWF 470
DVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLLKLARHSKFGMK F F
Sbjct: 421 DVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLLKLARHSKFGMKGFVLF 470
>gi|55956794 neurotrophic tyrosine kinase, receptor, type 3 isoform
c precursor [Homo sapiens]
Length = 612
Score = 356 bits (913), Expect = 4e-98
Identities = 220/569 (38%), Positives = 308/569 (54%), Gaps = 79/569 (13%)
Query: 10 PAMARLW-----GFCWLVVGFWRAAFACPTSCKCSASRIWCSDPSPGIVAFPRLEP---- 60
PA W G WL + + ACP +C CS + I C P G + FP LE
Sbjct: 7 PAKCSFWRIFLLGSVWL--DYVGSVLACPANCVCSKTEINCRRPDDGNL-FPLLEGQDSG 63
Query: 61 --------NSVD-PENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAF 111
N D NIT I I N + L +N D+E Y GL+ LTI +SGL+ + +AF
Sbjct: 64 NSNGNASINITDISRNITSIHIENWRSLHTLNAVDMELYTGLQKLTIKNSGLRSIQPRAF 123
Query: 112 LKNSNLQHINFTRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIKTLQE-AKSSPD 170
KN +L++IN + N+LT+LS + F+ L L EL L N F CSCDI W++ QE ++ +
Sbjct: 124 AKNPHLRYINLSSNRLTTLSWQLFQTLSLRELQLEQNFFNCSCDIRWMQLWQEQGEAKLN 183
Query: 171 TQDLYCLNESSKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYW 230
+Q+LYC+N +PL + I C LP +++ NLTV EG + ++C+ +G P+P++ W
Sbjct: 184 SQNLYCINADGSQLPLFRMNISQCDLPEISVSHVNLTVREGDNAVITCNGSGSPLPDVDW 243
Query: 231 DVGNLVS-----KHMNETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHF 285
V L S ++N T+ +L + N++S+D+G ++C+AEN+VG SV LTV++
Sbjct: 244 IVTGLQSINTHQTNLNWTNVHAINLTLVNVTSEDNGFTLTCIAENVVGMSNASVALTVYY 303
Query: 286 APTITFLESPTSDHHWCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYH-- 343
P + LE P CI F V+GNP P L W +NG L ESK I H EY+
Sbjct: 304 PPRVVSLEEPELRLEHCIEFVVRGNPPPTLHWLHNGQPLRESKII--------HVEYYQE 355
Query: 344 -----GCLQLDNPTHMNNGDYTLIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYE 398
GCL + PTH NNG+YTLIAKN G + I+ HF+ P + N ++++
Sbjct: 356 GEISEGCLLFNKPTHYNNGNYTLIAKNPLGTANQTINGHFLKEPFPESTDN----FILFD 411
Query: 399 DYGTAANDIGDTTNRSNEIPSTDVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLL--KL 456
+ P VT K + V V +A+ LLV+LF++ K
Sbjct: 412 EVSPT--------------PPITVTHKPEEDTFGVSIAVGLAAFA-CVLLVVLFVMINKY 456
Query: 457 ARHSKFGMKDFSWFGFGKVKSRQGVGPASVISNDDDSASPLHHISNGSNTPSSSEGGPDA 516
R SKFGMK GP +VIS ++DSASPLHHI++G TPSS + GPD
Sbjct: 457 GRRSKFGMK----------------GPVAVISGEEDSASPLHHINHGITTPSSLDAGPDT 500
Query: 517 VIIGMTKIPVIENPQYFGITNSQLKPDTW 545
V+IGMT+IPVIENPQYF ++ KPDTW
Sbjct: 501 VVIGMTRIPVIENPQYFRQGHNCHKPDTW 529
>gi|59889562 neurotrophic tyrosine kinase, receptor, type 3 isoform
a precursor [Homo sapiens]
Length = 839
Score = 352 bits (904), Expect = 4e-97
Identities = 220/569 (38%), Positives = 308/569 (54%), Gaps = 79/569 (13%)
Query: 10 PAMARLW-----GFCWLVVGFWRAAFACPTSCKCSASRIWCSDPSPGIVAFPRLEP---- 60
PA W G WL + + ACP +C CS + I C P G + FP LE
Sbjct: 7 PAKCSFWRIFLLGSVWL--DYVGSVLACPANCVCSKTEINCRRPDDGNL-FPLLEGQDSG 63
Query: 61 --------NSVD-PENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAF 111
N D NIT I I N + L +N D+E Y GL+ LTI +SGL+ + +AF
Sbjct: 64 NSNGNASINITDISRNITSIHIENWRSLHTLNAVDMELYTGLQKLTIKNSGLRSIQPRAF 123
Query: 112 LKNSNLQHINFTRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIKTLQE-AKSSPD 170
KN +L++IN + N+LT+LS + F+ L L EL L N F CSCDI W++ QE ++ +
Sbjct: 124 AKNPHLRYINLSSNRLTTLSWQLFQTLSLRELQLEQNFFNCSCDIRWMQLWQEQGEAKLN 183
Query: 171 TQDLYCLNESSKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYW 230
+Q+LYC+N +PL + I C LP +++ NLTV EG + ++C+ +G P+P++ W
Sbjct: 184 SQNLYCINADGSQLPLFRMNISQCDLPEISVSHVNLTVREGDNAVITCNGSGSPLPDVDW 243
Query: 231 DVGNLVS-----KHMNETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHF 285
V L S ++N T+ +L + N++S+D+G ++C+AEN+VG SV LTV++
Sbjct: 244 IVTGLQSINTHQTNLNWTNVHAINLTLVNVTSEDNGFTLTCIAENVVGMSNASVALTVYY 303
Query: 286 APTITFLESPTSDHHWCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYH-- 343
P + LE P CI F V+GNP P L W +NG L ESK I H EY+
Sbjct: 304 PPRVVSLEEPELRLEHCIEFVVRGNPPPTLHWLHNGQPLRESKII--------HVEYYQE 355
Query: 344 -----GCLQLDNPTHMNNGDYTLIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYE 398
GCL + PTH NNG+YTLIAKN G + I+ HF+ P +P+
Sbjct: 356 GEISEGCLLFNKPTHYNNGNYTLIAKNPLGTANQTINGHFLKEP---------FPE---- 402
Query: 399 DYGTAANDIGDTTNRSNEIPSTDVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLL--KL 456
+ D + + P VT K + V V +A+ LLV+LF++ K
Sbjct: 403 -----STDNFILFDEVSPTPPITVTHKPEEDTFGVSIAVGLAA-FACVLLVVLFVMINKY 456
Query: 457 ARHSKFGMKDFSWFGFGKVKSRQGVGPASVISNDDDSASPLHHISNGSNTPSSSEGGPDA 516
R SKFGMK GP +VIS ++DSASPLHHI++G TPSS + GPD
Sbjct: 457 GRRSKFGMK----------------GPVAVISGEEDSASPLHHINHGITTPSSLDAGPDT 500
Query: 517 VIIGMTKIPVIENPQYFGITNSQLKPDTW 545
V+IGMT+IPVIENPQYF ++ KPDT+
Sbjct: 501 VVIGMTRIPVIENPQYFRQGHNCHKPDTY 529
>gi|59889560 neurotrophic tyrosine kinase, receptor, type 3 isoform
b precursor [Homo sapiens]
Length = 825
Score = 352 bits (904), Expect = 4e-97
Identities = 220/569 (38%), Positives = 308/569 (54%), Gaps = 79/569 (13%)
Query: 10 PAMARLW-----GFCWLVVGFWRAAFACPTSCKCSASRIWCSDPSPGIVAFPRLEP---- 60
PA W G WL + + ACP +C CS + I C P G + FP LE
Sbjct: 7 PAKCSFWRIFLLGSVWL--DYVGSVLACPANCVCSKTEINCRRPDDGNL-FPLLEGQDSG 63
Query: 61 --------NSVD-PENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAF 111
N D NIT I I N + L +N D+E Y GL+ LTI +SGL+ + +AF
Sbjct: 64 NSNGNASINITDISRNITSIHIENWRSLHTLNAVDMELYTGLQKLTIKNSGLRSIQPRAF 123
Query: 112 LKNSNLQHINFTRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIKTLQE-AKSSPD 170
KN +L++IN + N+LT+LS + F+ L L EL L N F CSCDI W++ QE ++ +
Sbjct: 124 AKNPHLRYINLSSNRLTTLSWQLFQTLSLRELQLEQNFFNCSCDIRWMQLWQEQGEAKLN 183
Query: 171 TQDLYCLNESSKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYW 230
+Q+LYC+N +PL + I C LP +++ NLTV EG + ++C+ +G P+P++ W
Sbjct: 184 SQNLYCINADGSQLPLFRMNISQCDLPEISVSHVNLTVREGDNAVITCNGSGSPLPDVDW 243
Query: 231 DVGNLVS-----KHMNETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHF 285
V L S ++N T+ +L + N++S+D+G ++C+AEN+VG SV LTV++
Sbjct: 244 IVTGLQSINTHQTNLNWTNVHAINLTLVNVTSEDNGFTLTCIAENVVGMSNASVALTVYY 303
Query: 286 APTITFLESPTSDHHWCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYH-- 343
P + LE P CI F V+GNP P L W +NG L ESK I H EY+
Sbjct: 304 PPRVVSLEEPELRLEHCIEFVVRGNPPPTLHWLHNGQPLRESKII--------HVEYYQE 355
Query: 344 -----GCLQLDNPTHMNNGDYTLIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYE 398
GCL + PTH NNG+YTLIAKN G + I+ HF+ P +P+
Sbjct: 356 GEISEGCLLFNKPTHYNNGNYTLIAKNPLGTANQTINGHFLKEP---------FPE---- 402
Query: 399 DYGTAANDIGDTTNRSNEIPSTDVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLL--KL 456
+ D + + P VT K + V V +A+ LLV+LF++ K
Sbjct: 403 -----STDNFILFDEVSPTPPITVTHKPEEDTFGVSIAVGLAA-FACVLLVVLFVMINKY 456
Query: 457 ARHSKFGMKDFSWFGFGKVKSRQGVGPASVISNDDDSASPLHHISNGSNTPSSSEGGPDA 516
R SKFGMK GP +VIS ++DSASPLHHI++G TPSS + GPD
Sbjct: 457 GRRSKFGMK----------------GPVAVISGEEDSASPLHHINHGITTPSSLDAGPDT 500
Query: 517 VIIGMTKIPVIENPQYFGITNSQLKPDTW 545
V+IGMT+IPVIENPQYF ++ KPDT+
Sbjct: 501 VVIGMTRIPVIENPQYFRQGHNCHKPDTY 529
>gi|59889558 neurotrophic tyrosine kinase, receptor, type 1 isoform
1 [Homo sapiens]
Length = 790
Score = 247 bits (631), Expect = 2e-65
Identities = 178/536 (33%), Positives = 265/536 (49%), Gaps = 65/536 (12%)
Query: 7 WHGPAMARLWGFCWLVVGFWRAAFACPTSCKCSASRIWCSDPSPGIVAFPRLEPNSVD-- 64
WH A WL++ AA CP +C C S G+ +S+
Sbjct: 12 WHSWAAGPGSLLAWLILASAGAA-PCPDAC--------CPHGSSGLRCTRDGALDSLHHL 62
Query: 65 --PENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAFLKNSNLQHINF 122
EN+TE++I NQ+ L+ + D+ LRNLTIV SGL+FVA AF L +N
Sbjct: 63 PGAENLTELYIENQQHLQHLELRDLRGLGELRNLTIVKSGLRFVAPDAFHFTPRLSRLNL 122
Query: 123 TRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIKTL-QEAKSSPDTQDLYCLNESS 181
+ N L SLS K + L L EL+L GNP CSC + W++ +E Q L C +
Sbjct: 123 SFNALESLSWKTVQGLSLQELVLSGNPLHCSCALRWLQRWEEEGLGGVPEQKLQCHGQG- 181
Query: 182 KNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHMN 241
PLA++ +CG+P+ + PN +V+ G + L C V G + W + L
Sbjct: 182 ---PLAHMPNASCGVPTLKVQVPNASVDVGDDVLLRCQVEGRGLEQAGWILTELEQSATV 238
Query: 242 ETSHTQGSLRIT--NISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDH 299
S SL +T N++SD + K ++C AEN VG + SV + V F P L + H
Sbjct: 239 MKSGGLPSLGLTLANVTSDLNRKNVTCWAENDVGRAEVSVQVNVSF-PASVQLHTAVEMH 297
Query: 300 HWCIPFTVKGNPKPALQWFYNGAILNESKYICTKI--HVTNHTEYHGCLQLDNPTHMNNG 357
HWCIPF+V G P P+L+W +NG++LNE+ +I T+ N T HGCL+L+ PTH+NNG
Sbjct: 298 HWCIPFSVDGQPAPSLRWLFNGSVLNETSFIFTEFLEPAANETVRHGCLRLNQPTHVNNG 357
Query: 358 DYTLIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYEDYGTAANDIGDTTNRSNEI 417
+YTL+A N +G+ I A FM D+ N D I + T+ GD + +E
Sbjct: 358 NYTLLAANPFGQASASIMAAFM-----DNPFEFNPEDPIPDTNSTS----GDPVEKKDET 408
Query: 418 PSTDVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLLKLARHSKFGMKDFSWFGFGKVKS 477
P V+ G L+V+A + +++ ++L L K R +KF
Sbjct: 409 P-FGVSVAVG---LAVFACLFLST-------LLLVLNKCGRRNKF--------------- 442
Query: 478 RQGVGPASVISNDDDSASPLHHISNGSNTPSSSEGGPDAVIIGMTKIPVIENPQYF 533
G+ +V++ +D A LH ++ G ++ S +EG + + +IENPQYF
Sbjct: 443 --GINRPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGL-----QGHIIENPQYF 491
>gi|4585712 neurotrophic tyrosine kinase, receptor, type 1 isoform 2
[Homo sapiens]
Length = 796
Score = 247 bits (631), Expect = 2e-65
Identities = 177/536 (33%), Positives = 263/536 (49%), Gaps = 59/536 (11%)
Query: 7 WHGPAMARLWGFCWLVVGFWRAAFACPTSCKCSASRIWCSDPSPGIVAFPRLEPNSVD-- 64
WH A WL++ AA CP +C C S G+ +S+
Sbjct: 12 WHSWAAGPGSLLAWLILASAGAA-PCPDAC--------CPHGSSGLRCTRDGALDSLHHL 62
Query: 65 --PENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAFLKNSNLQHINF 122
EN+TE++I NQ+ L+ + D+ LRNLTIV SGL+FVA AF L +N
Sbjct: 63 PGAENLTELYIENQQHLQHLELRDLRGLGELRNLTIVKSGLRFVAPDAFHFTPRLSRLNL 122
Query: 123 TRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIKTL-QEAKSSPDTQDLYCLNESS 181
+ N L SLS K + L L EL+L GNP CSC + W++ +E Q L C +
Sbjct: 123 SFNALESLSWKTVQGLSLQELVLSGNPLHCSCALRWLQRWEEEGLGGVPEQKLQCHGQG- 181
Query: 182 KNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHMN 241
PLA++ +CG+P+ + PN +V+ G + L C V G + W + L
Sbjct: 182 ---PLAHMPNASCGVPTLKVQVPNASVDVGDDVLLRCQVEGRGLEQAGWILTELEQSATV 238
Query: 242 ETSHTQGSLRIT--NISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDH 299
S SL +T N++SD + K ++C AEN VG + SV + V F P L + H
Sbjct: 239 MKSGGLPSLGLTLANVTSDLNRKNVTCWAENDVGRAEVSVQVNVSF-PASVQLHTAVEMH 297
Query: 300 HWCIPFTVKGNPKPALQWFYNGAILNESKYICTKI--HVTNHTEYHGCLQLDNPTHMNNG 357
HWCIPF+V G P P+L+W +NG++LNE+ +I T+ N T HGCL+L+ PTH+NNG
Sbjct: 298 HWCIPFSVDGQPAPSLRWLFNGSVLNETSFIFTEFLEPAANETVRHGCLRLNQPTHVNNG 357
Query: 358 DYTLIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYEDYGTAANDIGDTTNRSNEI 417
+YTL+A N +G+ I A FM P NP P + + GD + +E
Sbjct: 358 NYTLLAANPFGQASASIMAAFMDNP---FEFNPEDPIPVSFSPVDTNSTSGDPVEKKDET 414
Query: 418 PSTDVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLLKLARHSKFGMKDFSWFGFGKVKS 477
P V+ G L+V+A + +++ ++L L K R +KF
Sbjct: 415 P-FGVSVAVG---LAVFACLFLST-------LLLVLNKCGRRNKF--------------- 448
Query: 478 RQGVGPASVISNDDDSASPLHHISNGSNTPSSSEGGPDAVIIGMTKIPVIENPQYF 533
G+ +V++ +D A LH ++ G ++ S +EG + + +IENPQYF
Sbjct: 449 --GINRPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGL-----QGHIIENPQYF 497
>gi|56118210 neurotrophic tyrosine kinase, receptor, type 1 isoform
3 [Homo sapiens]
Length = 760
Score = 235 bits (600), Expect = 7e-62
Identities = 160/467 (34%), Positives = 239/467 (51%), Gaps = 52/467 (11%)
Query: 72 FIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAFLKNSNLQHINFTRNKLTSLS 131
+I NQ+ L+ + D+ LRNLTIV SGL+FVA AF L +N + N L SLS
Sbjct: 42 YIENQQHLQHLELRDLRGLGELRNLTIVKSGLRFVAPDAFHFTPRLSRLNLSFNALESLS 101
Query: 132 RKHFRHLDLSELILVGNPFTCSCDIMWIKTL-QEAKSSPDTQDLYCLNESSKNIPLANLQ 190
K + L L EL+L GNP CSC + W++ +E Q L C + PLA++
Sbjct: 102 WKTVQGLSLQELVLSGNPLHCSCALRWLQRWEEEGLGGVPEQKLQCHGQG----PLAHMP 157
Query: 191 IPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHMNETSHTQGSL 250
+CG+P+ + PN +V+ G + L C V G + W + L S SL
Sbjct: 158 NASCGVPTLKVQVPNASVDVGDDVLLRCQVEGRGLEQAGWILTELEQSATVMKSGGLPSL 217
Query: 251 RIT--NISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHHWCIPFTVK 308
+T N++SD + K ++C AEN VG + SV + V F P L + HHWCIPF+V
Sbjct: 218 GLTLANVTSDLNRKNVTCWAENDVGRAEVSVQVNVSF-PASVQLHTAVEMHHWCIPFSVD 276
Query: 309 GNPKPALQWFYNGAILNESKYICTKI--HVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNE 366
G P P+L+W +NG++LNE+ +I T+ N T HGCL+L+ PTH+NNG+YTL+A N
Sbjct: 277 GQPAPSLRWLFNGSVLNETSFIFTEFLEPAANETVRHGCLRLNQPTHVNNGNYTLLAANP 336
Query: 367 YGKDEKQISAHFMGWPGIDDGANPNYPDVIYEDYGTAANDIGDTTNRSNEIPSTDVTDKT 426
+G+ I A FM D+ N D I + T+ GD + +E P V+
Sbjct: 337 FGQASASIMAAFM-----DNPFEFNPEDPIPDTNSTS----GDPVEKKDETP-FGVSVAV 386
Query: 427 GREHLSVYAVVVIASVVGFCLLVMLFLLKLARHSKFGMKDFSWFGFGKVKSRQGVGPASV 486
G L+V+A + +++ ++L L K R +KF G+ +V
Sbjct: 387 G---LAVFACLFLST-------LLLVLNKCGRRNKF-----------------GINRPAV 419
Query: 487 ISNDDDSASPLHHISNGSNTPSSSEGGPDAVIIGMTKIPVIENPQYF 533
++ +D A LH ++ G ++ S +EG + + +IENPQYF
Sbjct: 420 LAPEDGLAMSLHFMTLGGSSLSPTEGKGSGL-----QGHIIENPQYF 461
>gi|94420689 neural cell adhesion molecule 1 isoform 1 [Homo
sapiens]
Length = 848
Score = 79.7 bits (195), Expect = 6e-15
Identities = 62/233 (26%), Positives = 102/233 (43%), Gaps = 24/233 (10%)
Query: 170 DTQDLYCLNESSKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMY 229
D + C+ E+ A + + P +E + +TL+C +GDP+P++
Sbjct: 281 DEAEYICIAENKAGEQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSIT 340
Query: 230 W--DVGNLVSK------HMNETSHTQ-GSLRITNISSDDSGKQISCVAENLVGEDQDSVN 280
W N+ S+ HM SH + SL + +I D+G+ I C A N +G+D S+
Sbjct: 341 WRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYI-CTASNTIGQDSQSMY 399
Query: 281 LTVHFAPTITFLESPTSDHHW-----CIPFTVKGNPKPALQWFYNGAILNESKYICTKIH 335
L V +AP L+ P + + W I V P + WF +G +L S Y KI+
Sbjct: 400 LEVQYAPK---LQGPVAVYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIY 456
Query: 336 VTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQ---ISAHFMGWPGID 385
T Y L++ + + G+Y A N G++ + + A P ID
Sbjct: 457 NTPSASY---LEVTPDSENDFGNYNCTAVNRIGQESLEFILVQADTPSSPSID 506
Score = 66.2 bits (160), Expect = 7e-11
Identities = 48/179 (26%), Positives = 82/179 (45%), Gaps = 11/179 (6%)
Query: 205 NLTVEEGKSITLSCSVAGDPVPNMYWDV-GNLVSKHMNET----SHTQGSLRITNISSDD 259
N T G+S+TL C G P P M W G + + ++ S L I + +D
Sbjct: 222 NATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKND 281
Query: 260 SGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTS---DHHWCIPFTVKGNPKPALQ 316
+ I C+AEN GE +++L V P IT++E+ T+ + + G+P P++
Sbjct: 282 EAEYI-CIAENKAGEQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSIT 340
Query: 317 WFYNGA-ILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQI 374
W + I +E K + + V +H L L + + + G+Y A N G+D + +
Sbjct: 341 WRTSTRNISSEEKTLDGHMVVRSHARV-SSLTLKSIQYTDAGEYICTASNTIGQDSQSM 398
>gi|115529478 neural cell adhesion molecule 1 isoform 3 [Homo
sapiens]
Length = 761
Score = 79.7 bits (195), Expect = 6e-15
Identities = 62/233 (26%), Positives = 102/233 (43%), Gaps = 24/233 (10%)
Query: 170 DTQDLYCLNESSKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMY 229
D + C+ E+ A + + P +E + +TL+C +GDP+P++
Sbjct: 281 DEAEYICIAENKAGEQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSIT 340
Query: 230 W--DVGNLVSK------HMNETSHTQ-GSLRITNISSDDSGKQISCVAENLVGEDQDSVN 280
W N+ S+ HM SH + SL + +I D+G+ I C A N +G+D S+
Sbjct: 341 WRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYI-CTASNTIGQDSQSMY 399
Query: 281 LTVHFAPTITFLESPTSDHHW-----CIPFTVKGNPKPALQWFYNGAILNESKYICTKIH 335
L V +AP L+ P + + W I V P + WF +G +L S Y KI+
Sbjct: 400 LEVQYAPK---LQGPVAVYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIY 456
Query: 336 VTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQ---ISAHFMGWPGID 385
T Y L++ + + G+Y A N G++ + + A P ID
Sbjct: 457 NTPSASY---LEVTPDSENDFGNYNCTAVNRIGQESLEFILVQADTPSSPSID 506
Score = 66.2 bits (160), Expect = 7e-11
Identities = 48/179 (26%), Positives = 82/179 (45%), Gaps = 11/179 (6%)
Query: 205 NLTVEEGKSITLSCSVAGDPVPNMYWDV-GNLVSKHMNET----SHTQGSLRITNISSDD 259
N T G+S+TL C G P P M W G + + ++ S L I + +D
Sbjct: 222 NATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKND 281
Query: 260 SGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTS---DHHWCIPFTVKGNPKPALQ 316
+ I C+AEN GE +++L V P IT++E+ T+ + + G+P P++
Sbjct: 282 EAEYI-CIAENKAGEQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSIT 340
Query: 317 WFYNGA-ILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQI 374
W + I +E K + + V +H L L + + + G+Y A N G+D + +
Sbjct: 341 WRTSTRNISSEEKTLDGHMVVRSHARV-SSLTLKSIQYTDAGEYICTASNTIGQDSQSM 398
>gi|115529482 neural cell adhesion molecule 1 isoform 2 [Homo
sapiens]
Length = 858
Score = 75.9 bits (185), Expect = 9e-14
Identities = 62/243 (25%), Positives = 102/243 (41%), Gaps = 34/243 (13%)
Query: 170 DTQDLYCLNESSKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMY 229
D + C+ E+ A + + P +E + +TL+C +GDP+P++
Sbjct: 281 DEAEYICIAENKAGEQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSIT 340
Query: 230 W--DVGNLVSK----------------HMNETSHTQ-GSLRITNISSDDSGKQISCVAEN 270
W N+ S+ HM SH + SL + +I D+G+ I C A N
Sbjct: 341 WRTSTRNISSEEKASWTRPEKQETLDGHMVVRSHARVSSLTLKSIQYTDAGEYI-CTASN 399
Query: 271 LVGEDQDSVNLTVHFAPTITFLESPTSDHHW-----CIPFTVKGNPKPALQWFYNGAILN 325
+G+D S+ L V +AP L+ P + + W I V P + WF +G +L
Sbjct: 400 TIGQDSQSMYLEVQYAPK---LQGPVAVYTWEGNQVNITCEVFAYPSATISWFRDGQLLP 456
Query: 326 ESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQ---ISAHFMGWP 382
S Y KI+ T Y L++ + + G+Y A N G++ + + A P
Sbjct: 457 SSNYSNIKIYNTPSASY---LEVTPDSENDFGNYNCTAVNRIGQESLEFILVQADTPSSP 513
Query: 383 GID 385
ID
Sbjct: 514 SID 516
Score = 61.6 bits (148), Expect = 2e-09
Identities = 48/188 (25%), Positives = 81/188 (43%), Gaps = 19/188 (10%)
Query: 205 NLTVEEGKSITLSCSVAGDPVPNMYWDV-GNLVSKHMNET----SHTQGSLRITNISSDD 259
N T G+S+TL C G P P M W G + + ++ S L I + +D
Sbjct: 222 NATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKND 281
Query: 260 SGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTS---DHHWCIPFTVKGNPKPALQ 316
+ I C+AEN GE +++L V P IT++E+ T+ + + G+P P++
Sbjct: 282 EAEYI-CIAENKAGEQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSIT 340
Query: 317 WFYNGA-ILNESKYICTKIHVTNHTEYH---------GCLQLDNPTHMNNGDYTLIAKNE 366
W + I +E K T+ + H L L + + + G+Y A N
Sbjct: 341 WRTSTRNISSEEKASWTRPEKQETLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNT 400
Query: 367 YGKDEKQI 374
G+D + +
Sbjct: 401 IGQDSQSM 408
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 75.5 bits (184), Expect = 1e-13
Identities = 55/209 (26%), Positives = 93/209 (44%), Gaps = 21/209 (10%)
Query: 188 NLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGN--LVSKHMNETSH 245
N+ +P P +L V+ G+ + + C+ G P+P + W G ++ + S+
Sbjct: 1166 NVHVP----PKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSN 1221
Query: 246 TQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESP--------TS 297
G+L I + D+G +CVA N+ G D+ + L V PT+ LE P +
Sbjct: 1222 PDGTLSIDQATPSDAGIY-TCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVA 1280
Query: 298 DHHWCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNG 357
+ P KG PKP ++W +NG L + + + E L + + T +NG
Sbjct: 1281 NQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISIL------EDGTLLVIASVTPYDNG 1334
Query: 358 DYTLIAKNEYGKDEKQISAHFMGWPGIDD 386
+Y +A NE G E++ + P I D
Sbjct: 1335 EYICVAVNEAGTTERKYNLKVHVPPVIKD 1363
Score = 72.8 bits (177), Expect = 8e-13
Identities = 57/188 (30%), Positives = 83/188 (44%), Gaps = 17/188 (9%)
Query: 206 LTVEEGKSITLSCSVAGDPVPNMYW-DVGNLVSKHM-NETSHTQGSLRITNISSDDSGKQ 263
++V G+ +TL C V P P + W L+S T GS++IT + DSG
Sbjct: 1089 ISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMY 1148
Query: 264 ISCVAENLVGEDQDSVNLTVHFAPTITFLESPTS-----DHHWCIPFTVKGNPKPALQWF 318
+ CVA N+ G +V L VH P I P IP +G P P + W
Sbjct: 1149 L-CVATNIAGNVTQAVKLNVHVPPKIQ--RGPKHLKVQVGQRVDIPCNAQGTPLPVITWS 1205
Query: 319 YNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQISAHF 378
G+ + + + HV+N G L +D T + G YT +A N G DE +I+ H
Sbjct: 1206 KGGSTM----LVDGEHHVSNPD---GTLSIDQATPSDAGIYTCVATNIAGTDETEITLHV 1258
Query: 379 MGWPGIDD 386
P ++D
Sbjct: 1259 QEPPTVED 1266
Score = 72.0 bits (175), Expect = 1e-12
Identities = 55/194 (28%), Positives = 85/194 (43%), Gaps = 20/194 (10%)
Query: 188 NLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDV-GNLVSKHMNETSHT 246
N+Q+P P + + K ITLSC G P P++ W G + + + + +
Sbjct: 4074 NVQVP----PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLS 4129
Query: 247 QGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLE---SPTSDHHWCI 303
GSL+I + D+G +C+A N+ G S LTVH P I E + + +
Sbjct: 4130 SGSLQIAFVQPGDAG-HYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAIL 4188
Query: 304 PFTVKGNPKPALQWFYNGAILNE--SKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTL 361
P G P PA+ W + +L KY E +G L L+N ++G YT
Sbjct: 4189 PCVADGIPTPAINWKKDNVLLANLLGKYT---------AEPYGELILENVVLEDSGFYTC 4239
Query: 362 IAKNEYGKDEKQIS 375
+A N G+D +S
Sbjct: 4240 VANNAAGEDTHTVS 4253
Score = 69.3 bits (168), Expect = 9e-12
Identities = 67/233 (28%), Positives = 103/233 (44%), Gaps = 27/233 (11%)
Query: 170 DTQDLYC--LNESSKNIPLANLQIPNCGLPSANLAAP-NLTVEEGKSITLSCSVAGDPVP 226
D D C +NE+ + L + G P + P ++++E G ++TL C V G P P
Sbjct: 766 DAGDYTCVAINEAGRATGKITLDV---GSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEP 822
Query: 227 NMYW---DVGNLVSKHMNETSHTQ---GSLRITNISSDDSGKQISCVAENLVGEDQDSVN 280
+ W D + S+ + +S +Q G+L I N+ + D G I C AEN G+ Q
Sbjct: 823 TIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYI-CEAENQFGKIQSETT 881
Query: 281 LTVH--FAPTITFLESPTS---DHHWCIPFT-VKGNPKPALQWFYNGAILNESKYICTKI 334
+TV AP I S + +P T + GNP P +W N A+L ++ YI +
Sbjct: 882 VTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVR- 940
Query: 335 HVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQISAHFMGWPGIDDG 387
G L ++ + G+YT +A N G + K S P I G
Sbjct: 941 -------SDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHG 986
Score = 67.0 bits (162), Expect = 4e-11
Identities = 52/201 (25%), Positives = 93/201 (46%), Gaps = 18/201 (8%)
Query: 179 ESSKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSV-AGDPVPNMYWDVGN-LV 236
+S + + L P G+ S ++A V EG+ +TL C++ AG+P+P W + ++
Sbjct: 877 QSETTVTVTGLVAPLIGI-SPSVA----NVIEGQQLTLPCTLLAGNPIPERRWIKNSAML 931
Query: 237 SKHMNETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITF---LE 293
++ T + GSL I + D G + +CVA N+ G + + ++ VH PTI +
Sbjct: 932 LQNPYITVRSDGSLHIERVQLQDGG-EYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQIL 990
Query: 294 SPTSDHHWCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTH 353
S +P GNPKP++ W G +++ S G L + +P
Sbjct: 991 STIEGIPVTLPCKASGNPKPSVIWSKKGELISTSS-------AKFSAGADGSLYVVSPGG 1043
Query: 354 MNNGDYTLIAKNEYGKDEKQI 374
+G+Y A N G ++++
Sbjct: 1044 EESGEYVCTATNTAGYAKRKV 1064
Score = 65.5 bits (158), Expect = 1e-10
Identities = 50/167 (29%), Positives = 72/167 (43%), Gaps = 15/167 (8%)
Query: 207 TVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHM--NETSHTQGSLRITNISSDDSGKQI 264
TV E L C G P P + W N++ ++ T+ G L + N+ +DSG
Sbjct: 4179 TVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELILENVVLEDSGFY- 4237
Query: 265 SCVAENLVGEDQDSVNLTVHFAPTITFLESPTS---DHHWCIPFTVKGNPKPALQWFYNG 321
+CVA N GED +V+LTVH PT T L S + G P P L W +N
Sbjct: 4238 TCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNN 4297
Query: 322 AILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYG 368
I+ V H+E L ++ + ++G Y A+N G
Sbjct: 4298 NIIP-----AHFDSVNGHSE----LVIERVSKEDSGTYVCTAENSVG 4335
Score = 63.5 bits (153), Expect = 5e-10
Identities = 49/188 (26%), Positives = 83/188 (44%), Gaps = 21/188 (11%)
Query: 196 LPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHMNETSHTQGSLRITNI 255
LP+ ++++ +G+ + LSC G P+P + W N + ++ + L I +
Sbjct: 4259 LPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVNGHSELVIERV 4318
Query: 256 SSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHHWCIPF--------TV 307
S +DSG + C AEN VG + ++ P + + P+ +W P V
Sbjct: 4319 SKEDSGTYV-CTAENSVGFVK-AIGFVYVKEPPVFKGDYPS---NWIEPLGGNAILNCEV 4373
Query: 308 KGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEY 367
KG+P P +QW G + S I +G L + + + GDYT +A NE
Sbjct: 4374 KGDPTPTIQWNRKGVDIEISHRI--------RQLGNGSLAIYGTVNEDAGDYTCVATNEA 4425
Query: 368 GKDEKQIS 375
G E+ +S
Sbjct: 4426 GVVERSMS 4433
Score = 62.4 bits (150), Expect = 1e-09
Identities = 54/202 (26%), Positives = 85/202 (42%), Gaps = 18/202 (8%)
Query: 205 NLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHMNETSHTQGS--LRITNISSDDSGK 262
N++V E S++L+C +G P+P++ W N G LR+ + +D+G
Sbjct: 2395 NISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAG- 2453
Query: 263 QISCVAENLVGEDQDSVNLTVHFAPTI---TFLESPTSDHHWCIPFT--VKGNPKPALQW 317
Q +CV N GE++ L+V P I LE + T V GNP P + W
Sbjct: 2454 QYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITW 2513
Query: 318 FYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQISAH 377
+G L E + H+ + + LQ+ N + G YT +A + G + S +
Sbjct: 2514 HKDGQPLQEDE----AHHIISGGRF---LQITNVQVPHTGRYTCLASSPAGHKSRSFSLN 2566
Query: 378 FMGWP---GIDDGANPNYPDVI 396
P G+ NP VI
Sbjct: 2567 VFVSPTIAGVGSDGNPEDVTVI 2588
Score = 60.5 bits (145), Expect = 4e-09
Identities = 49/211 (23%), Positives = 87/211 (41%), Gaps = 14/211 (6%)
Query: 170 DTQDLYCLNESSKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMY 229
D + +C+ S A++ + P + N + G +++ CS G P P +
Sbjct: 585 DAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIA 644
Query: 230 WDVGN--LVSKHMNETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAP 287
W V + +V H + + G+L I N + D+G C+A N G D+ + L AP
Sbjct: 645 WTVNDMFIVGSHRYRMT-SDGTLFIKNAAPKDAG-IYGCLASNSAGTDKQNSTLRYIEAP 702
Query: 288 TITFLESP---TSDHHWCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHG 344
+ ++S + G P P ++WF L S ++ G
Sbjct: 703 KLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLII-------DPLLG 755
Query: 345 CLQLDNPTHMNNGDYTLIAKNEYGKDEKQIS 375
L++ ++ GDYT +A NE G+ +I+
Sbjct: 756 LLKIQETQDLDAGDYTCVAINEAGRATGKIT 786
Score = 60.5 bits (145), Expect = 4e-09
Identities = 51/201 (25%), Positives = 79/201 (39%), Gaps = 23/201 (11%)
Query: 197 PSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYW--DVGNLVSKHMNETSHTQGSLRITN 254
P+ +L + KS L C G P P + W D L H + G L I +
Sbjct: 3713 PNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQS 3772
Query: 255 ISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTS-----DHHWCIPFTVKG 309
D+G+ + C+A N G D+ ++L VH P+I PT+ + + G
Sbjct: 3773 AHVTDTGRYL-CMATNAAGTDRRRIDLQVHVPPSIA--PGPTNMTVIVNVQTTLACEATG 3829
Query: 310 NPKPALQWFYNGAILNESKYICTKIHVTNHTEYH----GCLQLDNPTHMNNGDYTLIAKN 365
PKP++ W NG +LN + N Y G L + +P+ + Y N
Sbjct: 3830 IPKPSINWRKNGHLLNVDQ---------NQNSYRLLSSGSLVIISPSVDDTATYECTVTN 3880
Query: 366 EYGKDEKQISAHFMGWPGIDD 386
G D++ + P I D
Sbjct: 3881 GAGDDKRTVDLTVQVPPSIAD 3901
Score = 60.1 bits (144), Expect = 5e-09
Identities = 53/193 (27%), Positives = 84/193 (43%), Gaps = 25/193 (12%)
Query: 197 PSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYW-DVGNLVSKHMNETSH---TQGSLRI 252
PS N+TV TL+C G P P++ W G+L++ N+ S+ + GSL I
Sbjct: 3804 PSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVI 3863
Query: 253 TNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESP-----TSDHHWCIPFTV 307
+ S DD+ C N G+D+ +V+LTV P+I + P T I T
Sbjct: 3864 ISPSVDDTA-TYECTVTNGAGDDKRTVDLTVQVPPSIA--DEPTDFLVTKHAPAVITCTA 3920
Query: 308 KGNPKPALQWFYNGAIL---NESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAK 364
G P P++ W NG L + I + G +++ + G YT +A+
Sbjct: 3921 SGVPFPSIHWTKNGIRLLPRGDGYRILSS----------GAIEILATQLNHAGRYTCVAR 3970
Query: 365 NEYGKDEKQISAH 377
N G + ++ H
Sbjct: 3971 NAAGSAHRHVTLH 3983
Score = 58.2 bits (139), Expect = 2e-08
Identities = 53/183 (28%), Positives = 79/183 (43%), Gaps = 18/183 (9%)
Query: 206 LTVEEGKSITLSCSVAGDPVPNMYWDV--GNLVSKHMNETSHTQGSLRI-TNISSDDSGK 262
LTV EG I+L C +G P PN+ W +++ M G ++ +I+
Sbjct: 2206 LTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAA 2265
Query: 263 QISCVAENLVGEDQDSVNLTVHFAPTITFLES------PTSDHHWCIPFTVKGNPKPALQ 316
SCVA N+ G + NL V+ PTIT S T + V+G P P +
Sbjct: 2266 LYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPTVT 2325
Query: 317 WFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQ--I 374
W +G L ++K + +I H LQL N + G Y +A N G +K+ +
Sbjct: 2326 WMKDGHPLIKAKGV--EILDEGH-----ILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDL 2378
Query: 375 SAH 377
S H
Sbjct: 2379 SVH 2381
Score = 58.2 bits (139), Expect = 2e-08
Identities = 51/180 (28%), Positives = 79/180 (43%), Gaps = 28/180 (15%)
Query: 205 NLTVEEGKSITLSCSVAGDPVPNMYW--DVGNLVSKHMNETSHTQGSLRITNISSDDSGK 262
++ V+E +S+TL+C V G+PVP + W D L + L+ITN+ +G+
Sbjct: 2488 DVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGR 2547
Query: 263 QISCVAENLVGEDQDSVNLTVHFAPTI-------------TFLESPTSDHHWCIPFTVKG 309
+C+A + G S +L V +PTI L SPTS +
Sbjct: 2548 -YTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTS-----LVCEAYS 2601
Query: 310 NPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGK 369
P + WF +G L ++ I +I T LQ+ N N G Y+ +A NE G+
Sbjct: 2602 YPPATITWFKDGTPLESNRNI--RILPGGRT-----LQILNAQEDNAGRYSCVATNEAGE 2654
Score = 57.0 bits (136), Expect = 4e-08
Identities = 49/190 (25%), Positives = 80/190 (42%), Gaps = 17/190 (8%)
Query: 205 NLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHMNETSHTQG--SLRITNISSDDSGK 262
NLTV I+L+C V+G P P++ W K T G +L+I D G
Sbjct: 2973 NLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGG- 3031
Query: 263 QISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSD-----HHWCIPFTVKGN--PKPAL 315
+ +C+A N GE + +LTV+ P+I +S + + + N P P +
Sbjct: 3032 EYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVI 3091
Query: 316 QWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQIS 375
W+ NG ++ ES T + + + L + + G Y A N G+D+K
Sbjct: 3092 TWYKNGRMITES----THVEILADGQ---MLHIKKAEVSDTGQYVCRAINVAGRDDKNFH 3144
Query: 376 AHFMGWPGID 385
+ P I+
Sbjct: 3145 LNVYVPPSIE 3154
Score = 56.6 bits (135), Expect = 6e-08
Identities = 46/175 (26%), Positives = 76/175 (43%), Gaps = 16/175 (9%)
Query: 206 LTVEEGKSITLSCSVAGDPVPNMYW--DVGNLVSKHMNETSHTQGSLRITNISSDDSGKQ 263
+ V GKSI+L C V G P P + W D L+ E L++ NI D+G+
Sbjct: 2302 IIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRY 2361
Query: 264 ISCVAENLVGEDQDSVNLTVHFAPTITFLE------SPTSDHHWCIPFTVKGNPKPALQW 317
+ CVA N+ G +L+VH P+I S + + G P P++ W
Sbjct: 2362 V-CVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITW 2420
Query: 318 FYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEK 372
F +G ++ + + + + L+L T + G YT + +N G++ K
Sbjct: 2421 FKDGWPVS----LSNSVRILSGGR---MLRLMQTTMEDAGQYTCVVRNAAGEERK 2468
Score = 55.5 bits (132), Expect = 1e-07
Identities = 55/200 (27%), Positives = 81/200 (40%), Gaps = 19/200 (9%)
Query: 196 LPSANLAAPN-LTVEEGKSITLSCSVAGDPVPNMYW--DVGNLVSKHMNETSHTQGSLRI 252
+ AN P +TV KS + C +G P P W D L+ ++ L+I
Sbjct: 2871 IKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQI 2930
Query: 253 TNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESP----TSDHHWCIPFTVK 308
N D G+ + CVAEN G + NL VH P++ +S ++ + V
Sbjct: 2931 LNTQITDIGRYV-CVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEVS 2989
Query: 309 GNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHG--CLQLDNPTHMNNGDYTLIAKNE 366
G P P L W N + + TN G LQ+ + G+YT IA N+
Sbjct: 2990 GFPPPDLSWLKNEQPIKLN---------TNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQ 3040
Query: 367 YGKDEKQISAHFMGWPGIDD 386
G+ +K+ S P I D
Sbjct: 3041 AGESKKKFSLTVYVPPSIKD 3060
Score = 54.7 bits (130), Expect = 2e-07
Identities = 46/173 (26%), Positives = 73/173 (42%), Gaps = 12/173 (6%)
Query: 206 LTVEEGKSITLSCSVAGDPVPNMYW-DVGNLVSKHMNETSHTQGS-LRITNISSDDSGKQ 263
+ V EG S++L C P P + W G ++++ + G L I D+G+
Sbjct: 3069 VNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQY 3128
Query: 264 ISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHHWCIPFTVK----GNPKPALQWFY 319
+ C A N+ G D + +L V+ P+I E P T+ G P P + W
Sbjct: 3129 V-CRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLK 3187
Query: 320 NGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEK 372
N + S + +I LQ+ H ++G+YT IA N GK +K
Sbjct: 3188 NHKRIENSDSLEVRILSGGSK-----LQIARSQHSDSGNYTCIASNMEGKAQK 3235
Score = 52.8 bits (125), Expect = 8e-07
Identities = 66/284 (23%), Positives = 110/284 (38%), Gaps = 53/284 (18%)
Query: 146 VGNPFTCSCD--------IMWIKTLQEAKSSPDTQDLYCLNESSKNIPLANLQIPNCG-- 195
+ NP T +CD I W+K + ++S D+ ++ L+ SK + +A Q + G
Sbjct: 3165 ISNPVTLTCDATGIPPPTIAWLKNHKRIENS-DSLEVRILSGGSK-LQIARSQHSDSGNY 3222
Query: 196 --------------------LPSANLAAP---NLTVEEGKSITLSCSVAGDPVPNMYW-D 231
+P + A +++V G+++ L C+ G P P + W
Sbjct: 3223 TCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLK 3282
Query: 232 VGNLVSKHMNE---TSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPT 288
G ++ E S +L I + D+GK +CVA N GE+ NL V+ PT
Sbjct: 3283 DGKPIASGETERIRVSANGSTLNIYGALTSDTGKY-TCVATNPAGEEDRIFNLNVYVTPT 3341
Query: 289 ITFLESPTS------DHHWCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEY 342
I + D I G P P + W NG L S +I ++
Sbjct: 3342 IRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHI--RLLAAGQV-- 3397
Query: 343 HGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQISAHFMGWPGIDD 386
+++ + YT +A N G D K + P +D+
Sbjct: 3398 ---IRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDN 3438
Score = 52.0 bits (123), Expect = 1e-06
Identities = 66/282 (23%), Positives = 104/282 (36%), Gaps = 49/282 (17%)
Query: 140 LSELILVGNPFTCSCD--------IMWIKTLQEAKSSPDTQDLYCLNESSKNIPLANLQI 191
L+E +LV NP C I W K + S L + I + + QI
Sbjct: 1928 LNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFL----NRGQIIDIESAQI 1983
Query: 192 PNCGL-----------------------PSANLAAPNLTVEEGKSITLSCSVAGDPVPNM 228
+ G+ PS + + + V + L C G P P++
Sbjct: 1984 SDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAPSL 2043
Query: 229 YW-DVGNLVSKHMNETSHTQGS--LRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHF 285
W G+ VS N G L +T+ D+G+ +CVA N GE Q ++L V+
Sbjct: 2044 TWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRY-TCVAVNAAGEKQRDIDLRVYV 2102
Query: 286 APTITFLESPTSD-HHWCIPFTVKGN--PKPALQWFYNGAILNESKYICTKIHVTNHTEY 342
P I E S + + + P P L W +G L + + + +E
Sbjct: 2103 PPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGL-------SISEN 2155
Query: 343 HGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQISAHFMGWPGI 384
L++++ + G YT A N GK EK + + P I
Sbjct: 2156 RSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNI 2197
Score = 51.2 bits (121), Expect = 2e-06
Identities = 56/245 (22%), Positives = 95/245 (38%), Gaps = 16/245 (6%)
Query: 161 TLQEAKSSPDTQDLY-CLNESSKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCS 219
TL ++P +Y CL +S N + P + L V G + C
Sbjct: 665 TLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECK 724
Query: 220 VAGDPVPNMYWDVGNLVSKHMNET--SHTQGSLRITNISSDDSGKQISCVAENLVGEDQD 277
+G P P + W G+L + G L+I D+G +CVA N G
Sbjct: 725 TSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAG-DYTCVAINEAGRATG 783
Query: 278 SVNLTVHFAPTITFLESPTS-----DHHWCIPFTVKGNPKPALQWFYNGAILNESKYICT 332
+ L V P F++ P + +P V+G P+P ++W L+
Sbjct: 784 KITLDVGSPPV--FIQEPADVSMEIGSNVTLPCYVQGYPEPTIKW----RRLDNMPIFSR 837
Query: 333 KIHVTNHTEYH-GCLQLDNPTHMNNGDYTLIAKNEYGKDEKQISAHFMGWPGIDDGANPN 391
V++ ++ G L + N + G Y A+N++GK + + + G G +P+
Sbjct: 838 PFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPS 897
Query: 392 YPDVI 396
+VI
Sbjct: 898 VANVI 902
Score = 51.2 bits (121), Expect = 2e-06
Identities = 49/202 (24%), Positives = 86/202 (42%), Gaps = 18/202 (8%)
Query: 179 ESSKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYW--DVGNLV 236
E SK+ L L+ P+ + + ++V + L+C +G P P M W D L
Sbjct: 3514 EVSKHFILKVLEPPHI---NGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLP 3570
Query: 237 SKHMNETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESP- 295
+T LRI+ +D+G+ +C+A + G+D + VH P I + P
Sbjct: 3571 QTDQVQTLGGGEVLRISTAQVEDTGRY-TCLASSPAGDDDKEYLVRVHVPPNIAGTDEPR 3629
Query: 296 --TSDHHWCIPFTVKGN--PKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNP 351
T + + K + P P + W NG L + ++ + + Y LQ++N
Sbjct: 3630 DITVLRNRQVTLECKSDAVPPPVITWLRNGERLQAT----PRVRILSGGRY---LQINNA 3682
Query: 352 THMNNGDYTLIAKNEYGKDEKQ 373
+ +YT +A N GK ++
Sbjct: 3683 DLGDTANYTCVASNIAGKTTRE 3704
Score = 50.8 bits (120), Expect = 3e-06
Identities = 48/190 (25%), Positives = 73/190 (38%), Gaps = 14/190 (7%)
Query: 205 NLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHMN--ETSHTQGSLRITNISSDDSGK 262
N++V + L C V G P P + W N+ + +T + L++ + +D+G+
Sbjct: 1369 NVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGR 1428
Query: 263 QISCVAENLVGEDQDSVNLTVHFAPTITFLESPTS-----DHHWCIPFTVKGNPKPALQW 317
SC A N+ G Q N+ V PTI P + + VKG P P + W
Sbjct: 1429 Y-SCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHW 1487
Query: 318 FYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQISAH 377
F +G L + + + + L L N + G Y N GK K I
Sbjct: 1488 FKDGKPLFLGD---PNVELLDRGQV---LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLT 1541
Query: 378 FMGWPGIDDG 387
P I G
Sbjct: 1542 IYIPPSIKGG 1551
Score = 50.1 bits (118), Expect = 5e-06
Identities = 51/179 (28%), Positives = 70/179 (39%), Gaps = 29/179 (16%)
Query: 213 SITLSCSVAGDPVPNMYWDVGNL---VSKHMNETSHTQGSLRITNISSDDSGKQISCVAE 269
SI + C G P P + W L +S H+ + Q +RI D +CVA
Sbjct: 3359 SINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQ-VIRIVRAQVSDVAVY-TCVAS 3416
Query: 270 NLVGEDQDSVNLTVHFAPT---------ITFLESPTSDHHWCIPFTVKGNPKPALQWFYN 320
N G D NL V P IT L+ +S CI G P P++ W +
Sbjct: 3417 NRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKG-SSTSMACI---TDGTPAPSMAWLRD 3472
Query: 321 GAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQISAHFM 379
G L ++ H LQL ++G YT IA NE G ++S HF+
Sbjct: 3473 GQPLGLDAHLTVSTHGM-------VLQLLKAETEDSGKYTCIASNEAG----EVSKHFI 3520
Score = 49.7 bits (117), Expect = 7e-06
Identities = 37/135 (27%), Positives = 59/135 (43%), Gaps = 14/135 (10%)
Query: 196 LPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDV-GNLVSKHMNETSH-TQGSLRIT 253
LP+ L+ EG +TL C +G+P P++ W G L+S + S GSL +
Sbjct: 980 LPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVV 1039
Query: 254 NISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLE-----------SPTSDHHWC 302
+ ++SG+ + C A N G + V LTV+ P + + S +
Sbjct: 1040 SPGGEESGEYV-CTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVT 1098
Query: 303 IPFTVKGNPKPALQW 317
+P VK P P + W
Sbjct: 1099 LPCEVKSLPPPIITW 1113
Score = 48.9 bits (115), Expect = 1e-05
Identities = 63/287 (21%), Positives = 107/287 (37%), Gaps = 52/287 (18%)
Query: 143 LILVGNPFTCSCD--------IMWIKTLQEAKSSPDTQDLYCLNESSKNIPLANLQIPNC 194
+++V N C IMW+K Q D +D + + + + + +A Q+ N
Sbjct: 1745 IVMVNNLLELDCHVTGSPPPTIMWLKDGQLI----DERDGFKILLNGRKLVIAQAQVSNT 1800
Query: 195 GL---PSANLAAPNL---------------------TVEEGKSITLSCSVAGDPVPNMYW 230
GL +AN A + V + K + L C G P P++ W
Sbjct: 1801 GLYRCMAANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITW 1860
Query: 231 DVGNLVSKHMNETSHTQGSLRITNISS---DDSGKQISCVAENLVGEDQDSVNLTVHFAP 287
+ Q S R+ I+ +D+G+ +CVA N GE Q + L VH P
Sbjct: 1861 LKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRY-TCVATNAAGETQQHIQLHVHEPP 1919
Query: 288 TI-----TFLESPTSDHHWCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEY 342
++ E+ + + GNP P + W+ + +L+ S T + N +
Sbjct: 1920 SLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGS----TSMTFLNRGQ- 1974
Query: 343 HGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQISAHFMGWPGIDDGAN 389
+ +++ + G Y +A N G E S P I N
Sbjct: 1975 --IIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNN 2019
Score = 48.1 bits (113), Expect = 2e-05
Identities = 55/203 (27%), Positives = 81/203 (39%), Gaps = 19/203 (9%)
Query: 205 NLTVEE---GKSITLSCSVAGDPVPNMYW--DVGNLVSKHMNETSHTQGSLR-ITNISSD 258
N T +E + I C G P P + W + L + + G+L I +++
Sbjct: 1272 NTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPY 1331
Query: 259 DSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHHWCIPFT-----VKGNPKP 313
D+G+ I CVA N G + NL VH P I E T+ T V+G P P
Sbjct: 1332 DNGEYI-CVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSP 1390
Query: 314 ALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQ 373
+ W+ + + ES I T V N L+L T + G Y+ A N G +K
Sbjct: 1391 IIMWYKDNVQVTESSTIQT---VNNGK----ILKLFRATPEDAGRYSCKAINIAGTSQKY 1443
Query: 374 ISAHFMGWPGIDDGANPNYPDVI 396
+ + P I PN V+
Sbjct: 1444 FNIDVLVPPTIIGTNFPNEVSVV 1466
Score = 48.1 bits (113), Expect = 2e-05
Identities = 45/181 (24%), Positives = 76/181 (41%), Gaps = 15/181 (8%)
Query: 200 NLAAPNLTVEEGKSITLSCSVAGDPVPNMYW-DVGNLVSKHMNETSHTQGS-LRITNISS 257
++ +TV +G S +++C G P P+M W G + + T T G L++ +
Sbjct: 3439 SMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAET 3498
Query: 258 DDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLE-----SPTSDHHWCIPFTVKGNPK 312
+DSGK +C+A N GE L V P I E S ++ + G P
Sbjct: 3499 EDSGK-YTCIASNEAGEVSKHFILKVLEPPHINGSEEHEEISVIVNNPLELTCIASGIPA 3557
Query: 313 PALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEK 372
P + W +G L ++ + T L++ + G YT +A + G D+K
Sbjct: 3558 PKMTWMKDGRPLPQTDQVQT-------LGGGEVLRISTAQVEDTGRYTCLASSPAGDDDK 3610
Query: 373 Q 373
+
Sbjct: 3611 E 3611
Score = 45.8 bits (107), Expect = 1e-04
Identities = 47/190 (24%), Positives = 77/190 (40%), Gaps = 22/190 (11%)
Query: 200 NLAAP-NLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHMNETSHTQGSLRITNISSD 258
NLA P N V S+TL C AG+P P + W + K + G ++ +S+
Sbjct: 1644 NLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQ 1703
Query: 259 DSGK-QISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHHWCIPFT--------VKG 309
+ + Q CVA ++ GE + + V P I E ++ + V G
Sbjct: 1704 EIDRGQYICVATSVAGEKEIKYEVDVLVPPAI---EGGDETSYFIVMVNNLLELDCHVTG 1760
Query: 310 NPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYG- 368
+P P + W +G +++E KI + L + N G Y +A N G
Sbjct: 1761 SPPPTIMWLKDGQLIDERDGF--KILLNGRK-----LVIAQAQVSNTGLYRCMAANTAGD 1813
Query: 369 -KDEKQISAH 377
K E +++ H
Sbjct: 1814 HKKEFEVTVH 1823
Score = 45.4 bits (106), Expect = 1e-04
Identities = 44/186 (23%), Positives = 73/186 (39%), Gaps = 19/186 (10%)
Query: 189 LQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGN--LVSKHMNETSHT 246
+Q+P PS + V + ++C+ +G P P+++W L+ + +
Sbjct: 3893 VQVP----PSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILS 3948
Query: 247 QGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTS---DHHWCI 303
G++ I + +G+ +CVA N G V L VH P I S ++ +
Sbjct: 3949 SGAIEILATQLNHAGRY-TCVARNAAGSAHRHVTLHVHEPPVIQPQPSELHVILNNPILL 4007
Query: 304 PFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEY-HGCLQLDNPTHMNNGDYTLI 362
P G P P + W G +N S NH G LQ+ + G Y +
Sbjct: 4008 PCEATGTPSPFITWQKEGINVNTSG--------RNHAVLPSGGLQISRAVREDAGTYMCV 4059
Query: 363 AKNEYG 368
A+N G
Sbjct: 4060 AQNPAG 4065
Score = 45.1 bits (105), Expect = 2e-04
Identities = 46/214 (21%), Positives = 83/214 (38%), Gaps = 28/214 (13%)
Query: 201 LAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSK---HMNETSHTQGSLRITNISS 257
L+ + ++ ++TL C P ++ W K H+N ++ +L+I
Sbjct: 2679 LSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGH-TLQIKEAQI 2737
Query: 258 DDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFL---------------ESPTSDHHWC 302
D+G+ +CVA N+ GED+ ++ + P+ L + ++
Sbjct: 2738 SDTGRY-TCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPIS 2796
Query: 303 IPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLI 362
+ P P L W+ +G L S + LQ+ + G YT +
Sbjct: 2797 LYCETNAAPPPTLTWYKDGHPLTSSDKVLI-------LPGGRVLQIPRAKVEDAGRYTCV 2849
Query: 363 AKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVI 396
A NE G+D Q + P I GAN + P+ +
Sbjct: 2850 AVNEAGEDSLQYDVRVL-VPPIIKGANSDLPEEV 2882
Score = 44.7 bits (104), Expect = 2e-04
Identities = 47/194 (24%), Positives = 72/194 (37%), Gaps = 25/194 (12%)
Query: 205 NLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHMNETSHTQGS--LRITNISSDDSGK 262
++TV + +TL C P P + W + G L+I N D+
Sbjct: 3630 DITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTAN 3689
Query: 263 QISCVAENLVGEDQDSVNLTVHFAPTITFLESPTS-----DHHWCIPFTVKGNPKPALQW 317
+CVA N+ G+ LTV+ P I P S + + +G P P + W
Sbjct: 3690 Y-TCVASNIAGKTTREFILTVNVPPNIK--GGPQSLVILLNKSTVLECIAEGVPTPRITW 3746
Query: 318 FYNGAILNESKYICTKIHVTNHTEY----HGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQ 373
+GA+L NH Y +G L + + + G Y +A N G D ++
Sbjct: 3747 RKDGAVL-----------AGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRR 3795
Query: 374 ISAHFMGWPGIDDG 387
I P I G
Sbjct: 3796 IDLQVHVPPSIAPG 3809
Score = 43.9 bits (102), Expect = 4e-04
Identities = 35/128 (27%), Positives = 57/128 (44%), Gaps = 12/128 (9%)
Query: 204 PN-LTVEEGKSITLSCSVAGDPVPNMYW--DVGNLVSKHMNETSHTQGS-LRITNISSDD 259
PN ++V + + L C V G P P+++W D L N +G L + N +D
Sbjct: 1460 PNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRND 1519
Query: 260 SGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHHWCIPFTVK------GNPKP 313
G+ C N G+ + LT++ P+I + T+D I +K G P P
Sbjct: 1520 KGR-YQCTVSNAAGKQAKDIKLTIYIPPSIKG-GNVTTDISVLINSLIKLECETRGLPMP 1577
Query: 314 ALQWFYNG 321
A+ W+ +G
Sbjct: 1578 AITWYKDG 1585
Score = 41.2 bits (95), Expect = 0.003
Identities = 42/164 (25%), Positives = 60/164 (36%), Gaps = 22/164 (13%)
Query: 214 ITLSCSVAGDPVPNMYWDVG--NLVSKHMNETSHTQGSLRITNISSDDSGKQISCVAENL 271
I L C G P P + W N+ + N G L+I+ +D+G + CVA+N
Sbjct: 4005 ILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYM-CVAQNP 4063
Query: 272 VGEDQDSVNLTVHFAPTITFLESP-------TSDHHWCIPFTVKGNPKPALQWFYNGAIL 324
G + L V P I SP D + G P P + W +G +
Sbjct: 4064 AGTALGKIKLNVQVPPVI----SPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAI 4119
Query: 325 NESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYG 368
ES + G LQ+ + G YT +A N G
Sbjct: 4120 VES--------IRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAG 4155
Score = 39.3 bits (90), Expect = 0.010
Identities = 42/169 (24%), Positives = 64/169 (37%), Gaps = 29/169 (17%)
Query: 249 SLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLE------SPTS----- 297
+L+I N D++G+ SCVA N GE + V+ P I + SP
Sbjct: 2630 TLQILNAQEDNAGRY-SCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKV 2688
Query: 298 DHHWCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNG 357
++ + P +L W+ +G L ++ I HT LQ+ + G
Sbjct: 2689 NNTLTLECEAYAIPSASLSWYKDGQPLKSDDHV--NIAANGHT-----LQIKEAQISDTG 2741
Query: 358 DYTLIAKNEYGKDEKQISAHFMGWPG----------IDDGANPNYPDVI 396
YT +A N G+DE + P +D G N DVI
Sbjct: 2742 RYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVI 2790
Score = 39.3 bits (90), Expect = 0.010
Identities = 25/105 (23%), Positives = 43/105 (40%), Gaps = 2/105 (1%)
Query: 170 DTQDLYCLNESSKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMY 229
D D C+ + + ++ + P L + G I L+C G+P P +
Sbjct: 4413 DAGDYTCVATNEAGVVERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTIT 4472
Query: 230 WD-VGNLVSKHMNETSHTQGSLRITNISSDDSGKQISCVAENLVG 273
W G+ +S + SL I + +D+ + CVA NL+G
Sbjct: 4473 WSRQGHSISWDDRVNVLSNNSLYIADAQKEDT-SEFECVARNLMG 4516
Score = 38.9 bits (89), Expect = 0.012
Identities = 42/187 (22%), Positives = 71/187 (37%), Gaps = 16/187 (8%)
Query: 214 ITLSCSVAGDPVPNMYW--DVGNLVSKHMNETSHTQGSLRITNISSDDSGKQISCVAENL 271
I L C G P+P + W D ++S L I DS +C N+
Sbjct: 1565 IKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATY-TCHVANV 1623
Query: 272 VGEDQDSVNLTVHFAPTITF-LESPTSD-----HHWCIPFTVKGNPKPALQWFYNGAILN 325
G + S ++ V+ P I L +P + H + GNP P L W +G +
Sbjct: 1624 AGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVK 1683
Query: 326 ESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQISAHFMGWPGID 385
+ I +I L++ + ++ G Y +A + G+ E + + P I+
Sbjct: 1684 ANDNI--RIEAGGKK-----LEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIE 1736
Query: 386 DGANPNY 392
G +Y
Sbjct: 1737 GGDETSY 1743
Score = 32.0 bits (71), Expect = 1.5
Identities = 44/192 (22%), Positives = 67/192 (34%), Gaps = 17/192 (8%)
Query: 214 ITLSCSVAGDPVPNMYW--DVGNLVSKHMNETSHTQGSLRITNISSDDSGKQISCVAENL 271
I+L C P P + W D L S L+I +D+G+ +CVA N
Sbjct: 2795 ISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRY-TCVAVNE 2853
Query: 272 VGEDQDSVNLTVHFAPTITFLESPTSDH-------HWCIPFTVKGNPKPALQWFYNGAIL 324
GED ++ V P I S + I G+P P W +G L
Sbjct: 2854 AGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPL 2913
Query: 325 NESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQISAHFMGWPGI 384
E + LQ+ N + G Y +A+N G +K + + P +
Sbjct: 2914 LEDDH-------HKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSV 2966
Query: 385 DDGANPNYPDVI 396
+ N V+
Sbjct: 2967 IGPKSENLTVVV 2978
>gi|126517478 peroxidasin homolog-like [Homo sapiens]
Length = 1463
Score = 73.2 bits (178), Expect = 6e-13
Identities = 92/414 (22%), Positives = 152/414 (36%), Gaps = 77/414 (18%)
Query: 18 FCW----LVVGFWRAAFACPTSCKCSASRIWCS----DPSPGI--------VAFPRLE-- 59
FCW L+ G+ CP+ C C S + C D P + + F R+
Sbjct: 6 FCWTTLFLLAGWCLPGLPCPSRCLCFKSTVRCMHLMLDHIPQVPQQTTVLDLRFNRIREI 65
Query: 60 PNSVDPE--NITEIFIAN-----------------------QKRLEIINEDDVEAYVGLR 94
P S + N+ + + N + + +++ + + L
Sbjct: 66 PGSAFKKLKNLNTLLLNNNHIRKISRNAFEGLENLLYLYLYKNEIHALDKQTFKGLISLE 125
Query: 95 NLTIVDSGLKFVAHKAFLKNSNLQHINFTRNKLTSLSRKHFRHLD-LSELILVGNPFTCS 153
+L I + L+ + + F L+ + NKL+ + F +LD L L L N C
Sbjct: 126 HLYIHFNQLEMLQPETFGDLLRLERLFLHNNKLSKIPAGSFSNLDSLKRLRLDSNALVCD 185
Query: 154 CDIMWIKTL-----QEAKSSPDTQDLYCLNESSKNIPLANLQIPNCGLPSANLAAPNLTV 208
CD+MW+ L Q + Y + + ++ NC P ++ V
Sbjct: 186 CDLMWLGELLQGFAQHGHTQAAATCEYPRRLHGRAVASVTVEEFNCQSPRITFEPQDVEV 245
Query: 209 EEGKSITLSCSVAGDPVPNMYWDVGNLVSKHMNETS---HTQGSLRITNISSDDSGKQIS 265
G ++ +C G+P P + W N ++T G+L I N D G
Sbjct: 246 PSGNTVYFTCRAEGNPKPEIIWIHNNHSLDLEDDTRLNVFDDGTLMIRNTRESDQG-VYQ 304
Query: 266 CVAENLVGEDQ-DSVNLTVHFAPT-ITFLESP--------TSDHHWCIPFTVKGNPKPAL 315
C+A N GE + S L P +F+ P TS C+ G+P P +
Sbjct: 305 CMARNSAGEAKTQSAMLRYSSLPAKPSFVIQPQDTEVLIGTSTTLECM---ATGHPHPLI 361
Query: 316 QWFY-NGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYG 368
W NG L+ S+++ T L L N T ++G +T A N +G
Sbjct: 362 TWTRDNGLELDGSRHVATS----------SGLYLQNITQRDHGRFTCHANNSHG 405
Score = 50.8 bits (120), Expect = 3e-06
Identities = 45/178 (25%), Positives = 71/178 (39%), Gaps = 15/178 (8%)
Query: 197 PSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWD-VGNLVSKHMNETSHTQGSLRITNI 255
P + + V E ++ C G+P P + W G + T + G+LRI
Sbjct: 419 PQFTVTPKDQVVLEEHAVEWLCEADGNPPPVIVWTKTGGQLPVEGQHTVLSSGTLRIDRA 478
Query: 256 SSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDH-----HWCIPFTVKGN 310
+ D G Q C A + +G + SV LTV F + P + I +G
Sbjct: 479 AQHDQG-QYECQAVSSLGVKKVSVQLTVKPKALAVFTQLPQDTSVEVGKNINISCHAQGE 537
Query: 311 PKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYG 368
P+P + W G + ES K HV + G L + + + G Y +A+N +G
Sbjct: 538 PQPIITWNKEGVQITESG----KFHVDDE----GTLTIYDAGFPDQGRYECVARNSFG 587
Score = 48.1 bits (113), Expect = 2e-05
Identities = 45/177 (25%), Positives = 66/177 (37%), Gaps = 16/177 (9%)
Query: 197 PSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHMNETSHTQGSLRITNIS 256
PS + + V G S TL C G P P + W N + + T L + NI+
Sbjct: 330 PSFVIQPQDTEVLIGTSTTLECMATGHPHPLITWTRDNGLELDGSRHVATSSGLYLQNIT 389
Query: 257 SDDSGKQISCVAENLVGEDQDSVNLTVHFAP--TITFLESPTSDHH---WCIPFTVKGNP 311
D G+ +C A N G Q + N+ V P T+T + + H W GNP
Sbjct: 390 QRDHGR-FTCHANNSHGTVQAAANIIVQAPPQFTVTPKDQVVLEEHAVEWLC--EADGNP 446
Query: 312 KPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYG 368
P + W G L + + G L++D + G Y A + G
Sbjct: 447 PPVIVWTKTGGQL--------PVEGQHTVLSSGTLRIDRAAQHDQGQYECQAVSSLG 495
Score = 37.7 bits (86), Expect = 0.028
Identities = 25/78 (32%), Positives = 40/78 (51%), Gaps = 2/78 (2%)
Query: 207 TVEEGKSITLSCSVAGDPVPNMYWD-VGNLVSKHMNETSHTQGSLRITNISSDDSGKQIS 265
+VE GK+I +SC G+P P + W+ G +++ +G+L I + D G+
Sbjct: 521 SVEVGKNINISCHAQGEPQPIITWNKEGVQITESGKFHVDDEGTLTIYDAGFPDQGR-YE 579
Query: 266 CVAENLVGEDQDSVNLTV 283
CVA N G ++ LTV
Sbjct: 580 CVARNSFGLAVTNMFLTV 597
>gi|42544233 leucine rich repeat neuronal 2 [Homo sapiens]
Length = 713
Score = 71.6 bits (174), Expect = 2e-12
Identities = 60/233 (25%), Positives = 101/233 (43%), Gaps = 20/233 (8%)
Query: 67 NITEIFIANQKRLEIINEDDVEAYVGLRNLTIVD----SGLKFVAHKAFLKNSNLQHINF 122
++ E+ + N + L I D A V L LT +D L F+ +AF ++ +
Sbjct: 286 HLKELGLNNMEELVSI---DKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLML 342
Query: 123 TRNKLTSLSRKHFRHL-DLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLNESS 181
N L++L ++ L +L E+ L GNP C C I W + Q C
Sbjct: 343 NNNALSALHQQTVESLPNLQEVGLHGNPIRCDCVIRWANATGTRVRFIEPQSTLCAEPPD 402
Query: 182 ------KNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVG-- 233
+ +P + L S P+L V G+S+ L C +P P +YW
Sbjct: 403 LQRLPVREVPFREMTDHCLPLISPRSFPPSLQVASGESMVLHCRALAEPEPEIYWVTPAG 462
Query: 234 -NLVSKHMNE--TSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTV 283
L H + +G+L + ++++++G +CVA+NLVG D +V++ V
Sbjct: 463 LRLTPAHAGRRYRVYPEGTLELRRVTAEEAG-LYTCVAQNLVGADTKTVSVVV 514
>gi|42544231 leucine rich repeat neuronal 2 [Homo sapiens]
Length = 713
Score = 71.6 bits (174), Expect = 2e-12
Identities = 60/233 (25%), Positives = 101/233 (43%), Gaps = 20/233 (8%)
Query: 67 NITEIFIANQKRLEIINEDDVEAYVGLRNLTIVD----SGLKFVAHKAFLKNSNLQHINF 122
++ E+ + N + L I D A V L LT +D L F+ +AF ++ +
Sbjct: 286 HLKELGLNNMEELVSI---DKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLML 342
Query: 123 TRNKLTSLSRKHFRHL-DLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLNESS 181
N L++L ++ L +L E+ L GNP C C I W + Q C
Sbjct: 343 NNNALSALHQQTVESLPNLQEVGLHGNPIRCDCVIRWANATGTRVRFIEPQSTLCAEPPD 402
Query: 182 ------KNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVG-- 233
+ +P + L S P+L V G+S+ L C +P P +YW
Sbjct: 403 LQRLPVREVPFREMTDHCLPLISPRSFPPSLQVASGESMVLHCRALAEPEPEIYWVTPAG 462
Query: 234 -NLVSKHMNE--TSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTV 283
L H + +G+L + ++++++G +CVA+NLVG D +V++ V
Sbjct: 463 LRLTPAHAGRRYRVYPEGTLELRRVTAEEAG-LYTCVAQNLVGADTKTVSVVV 514
>gi|41582239 immunoglobulin superfamily containing leucine-rich
repeat [Homo sapiens]
Length = 428
Score = 70.1 bits (170), Expect = 5e-12
Identities = 61/229 (26%), Positives = 96/229 (41%), Gaps = 32/229 (13%)
Query: 86 DVEAYVGLRNLTIVDSGLKFVAHKAFLKNSNLQHINFTRNKLTSLSRKHFRHLD-LSELI 144
D+ L+ L + + L F+ AF L+ + N+L +L+ F L LS L
Sbjct: 117 DLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLTALSHLQ 176
Query: 145 LVGNPFTCSCDIMWIKT--LQEAKSSPDTQDLYCLN-ESSKNIPLANLQIPNCGLPSANL 201
+ NPF C+C I+W+KT L A S P+ ++ C + K PL+ L C PS L
Sbjct: 177 INENPFDCTCGIVWLKTWALTTAVSIPEQDNIACTSPHVLKGTPLSRLPPLPCSAPSVQL 236
Query: 202 ----AAPNLTVEEGKSITLSCSVAGDPVPNMYW--------------DVGN--------- 234
+ + G + L C V G P P ++W +VG
Sbjct: 237 SYQPSQDGAELRPGFVLALHCDVDGQPAPQLHWHIQIPSGIVEITSPNVGTDGRALPGTP 296
Query: 235 LVSKHMNETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTV 283
+ S + GSL I + + G SC+A N +G + SV++ +
Sbjct: 297 VASSQPRFQAFANGSLLIPDFGKLEEG-TYSCLATNELGSAESSVDVAL 344
>gi|5031809 immunoglobulin superfamily containing leucine-rich
repeat [Homo sapiens]
Length = 428
Score = 70.1 bits (170), Expect = 5e-12
Identities = 61/229 (26%), Positives = 96/229 (41%), Gaps = 32/229 (13%)
Query: 86 DVEAYVGLRNLTIVDSGLKFVAHKAFLKNSNLQHINFTRNKLTSLSRKHFRHLD-LSELI 144
D+ L+ L + + L F+ AF L+ + N+L +L+ F L LS L
Sbjct: 117 DLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLTALSHLQ 176
Query: 145 LVGNPFTCSCDIMWIKT--LQEAKSSPDTQDLYCLN-ESSKNIPLANLQIPNCGLPSANL 201
+ NPF C+C I+W+KT L A S P+ ++ C + K PL+ L C PS L
Sbjct: 177 INENPFDCTCGIVWLKTWALTTAVSIPEQDNIACTSPHVLKGTPLSRLPPLPCSAPSVQL 236
Query: 202 ----AAPNLTVEEGKSITLSCSVAGDPVPNMYW--------------DVGN--------- 234
+ + G + L C V G P P ++W +VG
Sbjct: 237 SYQPSQDGAELRPGFVLALHCDVDGQPAPQLHWHIQIPSGIVEITSPNVGTDGRALPGTP 296
Query: 235 LVSKHMNETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTV 283
+ S + GSL I + + G SC+A N +G + SV++ +
Sbjct: 297 VASSQPRFQAFANGSLLIPDFGKLEEG-TYSCLATNELGSAESSVDVAL 344
>gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens]
Length = 1215
Score = 68.9 bits (167), Expect = 1e-11
Identities = 64/231 (27%), Positives = 94/231 (40%), Gaps = 22/231 (9%)
Query: 162 LQEAKSSPDTQDLYCLNESSKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVA 221
L+ +K+ T + C S A QI P + APN+TV G++ LSC V
Sbjct: 367 LRASKAEEGTYE--CTAVSRAGTGRAKAQIVVTDPPPQLVPAPNVTVSPGETAVLSCRVL 424
Query: 222 GDPVPNMYW--DVGNLVSKHMNETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSV 279
G+ N+ W D L + SL I+ I D G+ CVA N G + SV
Sbjct: 425 GEAPYNLTWVRDWRVLPASTGRVAQLADLSLEISGIIPTDGGR-YQCVASNANGVTRASV 483
Query: 280 NLTVHFAPTITFLESPTSDHHWCIPFTVK------GNPKPALQWFYNGAILNESKYICTK 333
L V AP ++ TS H+ VK G P P + W L E I
Sbjct: 484 WLLVREAPQVSI---HTSSQHFSQGVEVKVSCSASGYPTPHISWSRESQALQEDSRI--- 537
Query: 334 IHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQISAHFMGWPGI 384
H + G L + + G+Y+ A NE G D++ ++ ++ P +
Sbjct: 538 -----HVDAQGTLIIQGVAPEDAGNYSCQATNEVGTDQETVTLYYTDPPSV 583
Score = 53.5 bits (127), Expect = 5e-07
Identities = 46/206 (22%), Positives = 87/206 (42%), Gaps = 21/206 (10%)
Query: 176 CLNESSKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNL 235
C+ ++ + A++ + P ++ + +G + +SCS +G P P++ W +
Sbjct: 470 CVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISW---SR 526
Query: 236 VSKHMNETSH----TQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITF 291
S+ + E S QG+L I ++ +D+G SC A N VG DQ++V L P+++
Sbjct: 527 ESQALQEDSRIHVDAQGTLIIQGVAPEDAGNY-SCQATNEVGTDQETVTLYYTDPPSVSA 585
Query: 292 LES---PTSDHHWCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQL 348
+ + + G P P + W+ G ++ + G L++
Sbjct: 586 VNAVVLVAVGEEAVLVCEASGVPPPRVIWYRGG----------LEMILAPEGSSSGKLRI 635
Query: 349 DNPTHMNNGDYTLIAKNEYGKDEKQI 374
+ G YT A NE G +I
Sbjct: 636 PAAQERDAGTYTCRAVNELGDASAEI 661
Score = 45.4 bits (106), Expect = 1e-04
Identities = 48/207 (23%), Positives = 74/207 (35%), Gaps = 33/207 (15%)
Query: 187 ANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGN--------LVSK 238
A +Q+ P ++TVE G+S L+C G P P + W G+ +
Sbjct: 659 AEIQLAVGHAPQLTELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGR 718
Query: 239 HMNETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTV---------HFAPTI 289
G L +++ +D + C A N+ G+ Q L V APT+
Sbjct: 719 GSRSRQPDSGVLFFESVAPEDQAPYV-CEARNVFGKVQAEARLIVTGHAPPQIASSAPTV 777
Query: 290 TFLE-SPTSDHHWCIP-FTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQ 347
LE P S +P + G P P W +G L + G L
Sbjct: 778 RVLEGQPVS-----LPCIVLAGRPLPERHWLKDGRPLPPGS--------RHSIRADGSLH 824
Query: 348 LDNPTHMNNGDYTLIAKNEYGKDEKQI 374
LD + G Y+ +A N G + +
Sbjct: 825 LDRALQEHAGRYSCVATNTAGSQHRDV 851
Score = 44.7 bits (104), Expect = 2e-04
Identities = 35/141 (24%), Positives = 58/141 (41%), Gaps = 17/141 (12%)
Query: 189 LQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYW--DVGNLVSKHMNETSHT 246
+Q+P P + A + EG +L C +G P P + W + L S+ +
Sbjct: 855 VQVP----PRIHPTATHHITNEGVPASLPCVASGVPAPTITWTKETNALTSRGPHYNVSK 910
Query: 247 QGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSD-------- 298
+G+L I S+ D+G + C A N VG + L+V+ P I S ++
Sbjct: 911 EGTLLIAQPSAQDAGAYV-CTATNTVGFSSQEMRLSVNTKPRIHMNGSRNANVPLQVTAK 969
Query: 299 --HHWCIPFTVKGNPKPALQW 317
+ KG+P P + W
Sbjct: 970 AGEEVTLDCEAKGSPPPLVTW 990
Score = 42.4 bits (98), Expect = 0.001
Identities = 34/124 (27%), Positives = 49/124 (39%), Gaps = 5/124 (4%)
Query: 197 PSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHMNETSHTQGSLRITNIS 256
PS + + V G+ L C +G P P + W G L E S + G LRI
Sbjct: 581 PSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYRGGLEMILAPEGS-SSGKLRIPAAQ 639
Query: 257 SDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTS---DHHWCIPFTVKGNPKP 313
D+G +C A N +G+ + L V AP +T L + + G P P
Sbjct: 640 ERDAG-TYTCRAVNELGDASAEIQLAVGHAPQLTELPRDVTVELGRSALLACRATGRPPP 698
Query: 314 ALQW 317
+ W
Sbjct: 699 TVTW 702
Score = 33.9 bits (76), Expect = 0.40
Identities = 28/109 (25%), Positives = 39/109 (35%), Gaps = 4/109 (3%)
Query: 198 SANLAAP-NLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHMNETSH--TQGSLRITN 254
S N P +T + G+ +TL C G P P + W + + GSLR+
Sbjct: 957 SRNANVPLQVTAKAGEEVTLDCEAKGSPPPLVTWTKDSRPVPPITNRYGLLPSGSLRLAQ 1016
Query: 255 ISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHHWCI 303
+ DSG C A N G L V + P H C+
Sbjct: 1017 VQVGDSG-HYECTASNPAGSASHRYVLGVQGRTSWQPQSLPVPHHPACL 1064
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 68.9 bits (167), Expect = 1e-11
Identities = 64/231 (27%), Positives = 94/231 (40%), Gaps = 22/231 (9%)
Query: 162 LQEAKSSPDTQDLYCLNESSKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVA 221
L+ +K+ T + C S A QI P + APN+TV G++ LSC V
Sbjct: 484 LRASKAEEGTYE--CTAVSRAGTGRAKAQIVVTDPPPQLVPAPNVTVSPGETAVLSCRVL 541
Query: 222 GDPVPNMYW--DVGNLVSKHMNETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSV 279
G+ N+ W D L + SL I+ I D G+ CVA N G + SV
Sbjct: 542 GEAPYNLTWVRDWRVLPASTGRVAQLADLSLEISGIIPTDGGR-YQCVASNANGVTRASV 600
Query: 280 NLTVHFAPTITFLESPTSDHHWCIPFTVK------GNPKPALQWFYNGAILNESKYICTK 333
L V AP ++ TS H+ VK G P P + W L E I
Sbjct: 601 WLLVREAPQVSI---HTSSQHFSQGVEVKVSCSASGYPTPHISWSRESQALQEDSRI--- 654
Query: 334 IHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQISAHFMGWPGI 384
H + G L + + G+Y+ A NE G D++ ++ ++ P +
Sbjct: 655 -----HVDAQGTLIIQGVAPEDAGNYSCQATNEVGTDQETVTLYYTDPPSV 700
Score = 67.0 bits (162), Expect = 4e-11
Identities = 58/223 (26%), Positives = 91/223 (40%), Gaps = 18/223 (8%)
Query: 162 LQEAKSSPDTQDLY-CLNESSKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSV 220
L+ A +SP+ Y C+ ++S + ++ P P+L+ EG L C
Sbjct: 4002 LRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKA 4061
Query: 221 AGDPVPNMYWDV-GNLVSKHMNE-TSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDS 278
G P PN+ WD G VS + T G L + N+ D+G +C AEN VG +
Sbjct: 4062 RGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAG-TYTCTAENAVGRARRR 4120
Query: 279 VNLTVHFAPTITFLESPTS----DHHWCIPFTVKGNPKPALQWFYNGAILNESKYICTKI 334
V+LT+ P T L S D W + +G+P P + W N + E
Sbjct: 4121 VHLTILVLPVFTTLPGDRSLRLGDRLW-LRCAARGSPTPRIGWTVNDRPVTEG------- 4172
Query: 335 HVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQISAH 377
+ + LQ + ++G Y A+N G+ + H
Sbjct: 4173 --VSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVH 4213
Score = 57.8 bits (138), Expect = 3e-08
Identities = 50/164 (30%), Positives = 69/164 (42%), Gaps = 17/164 (10%)
Query: 211 GKSITLSCSVAGDPVPNMYWDVGNLVSKHMNETSHTQ-GSLRITNISSDDSGKQISCVAE 269
G SI L C V GDPVP+++W L + + Q GSL I DD+G+ C+AE
Sbjct: 4233 GGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGR-YQCLAE 4291
Query: 270 NLVGEDQDSVNLTVHFAPTITFLESP-----TSDHHWCIPFTVKGNPKPALQWFYNGAIL 324
N +G + V L + AP F P S + G P P ++W G L
Sbjct: 4292 NEMGVAKKVVILVLQSAP--VFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPL 4349
Query: 325 NESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYG 368
S+ + T G L L+N + G Y +A N G
Sbjct: 4350 RASRRL--------RTLPDGSLWLENVETGDAGTYDCVAHNLLG 4385
Score = 56.2 bits (134), Expect = 8e-08
Identities = 44/179 (24%), Positives = 76/179 (42%), Gaps = 18/179 (10%)
Query: 206 LTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHMNETSHTQG--SLRITNISSDDSGKQ 263
+ V E + L C G P PN+ W + + +T+G L++ S D+G
Sbjct: 1512 VAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAG-V 1570
Query: 264 ISCVAENLVGEDQDSVNLTVHFAPTI------TFLESPTSDHHWCIPFTVKGNPKPALQW 317
+C A N VG + + L V+ PTI ++ + + +G+P P L W
Sbjct: 1571 YTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGHPSPTLSW 1630
Query: 318 FYNGAILNESKYICTKIHVTNHTEYHG-CLQLDNPTHMNNGDYTLIAKNEYGKDEKQIS 375
+ G + ES + E G L+L++P ++G Y+ +A + G+ Q S
Sbjct: 1631 HHEGLPVAESN--------ESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYS 1681
Score = 54.3 bits (129), Expect = 3e-07
Identities = 49/166 (29%), Positives = 71/166 (42%), Gaps = 15/166 (9%)
Query: 214 ITLSCSVAGDPVPNMYW-DVGNLVSKHMNETSHTQGSLRITNISS---DDSGKQISCVAE 269
+ L+C+ G P P + W GN VS R+ ++S DSG+ SCVA
Sbjct: 1995 VRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRY-SCVAV 2053
Query: 270 NLVGEDQDSVNLTVHFAPTITFLE---SPTSDHHWCIPFTVKGNPKPALQWFYNGAILNE 326
+ VGED+ V L VH P+I E S ++ + P P L W+ +G L
Sbjct: 2054 SAVGEDRQDVVLQVHMPPSILGEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPLEP 2113
Query: 327 SKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEK 372
+H++ LQ+D + G YT A N+ G EK
Sbjct: 2114 R----PGVHLSAD---KALLQVDRADVWDAGHYTCEALNQAGHSEK 2152
Score = 53.5 bits (127), Expect = 5e-07
Identities = 46/206 (22%), Positives = 87/206 (42%), Gaps = 21/206 (10%)
Query: 176 CLNESSKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNL 235
C+ ++ + A++ + P ++ + +G + +SCS +G P P++ W +
Sbjct: 587 CVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISW---SR 643
Query: 236 VSKHMNETSH----TQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITF 291
S+ + E S QG+L I ++ +D+G SC A N VG DQ++V L P+++
Sbjct: 644 ESQALQEDSRIHVDAQGTLIIQGVAPEDAGNY-SCQATNEVGTDQETVTLYYTDPPSVSA 702
Query: 292 LES---PTSDHHWCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQL 348
+ + + G P P + W+ G ++ + G L++
Sbjct: 703 VNAVVLVAVGEEAVLVCEASGVPPPRVIWYRGG----------LEMILAPEGSSSGKLRI 752
Query: 349 DNPTHMNNGDYTLIAKNEYGKDEKQI 374
+ G YT A NE G +I
Sbjct: 753 PAAQERDAGTYTCRAVNELGDASAEI 778
Score = 52.8 bits (125), Expect = 8e-07
Identities = 52/224 (23%), Positives = 93/224 (41%), Gaps = 19/224 (8%)
Query: 164 EAKSSPDTQDLYCLNESSKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGD 223
+A S+ D+ D C ++ ++ +P+ P + V ++ L C G
Sbjct: 3640 QALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGV 3699
Query: 224 PVPNMYW--DVGNLVSKHMNETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNL 281
P P + W D L + +GSLRI + + D+G + C+A N G D+ +L
Sbjct: 3700 PAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYL-CLASNSAGSDRQGRDL 3758
Query: 282 TVHFAPTITFLESP-----TSDHHWCIPFTVKGNPKPALQWFYNGAILN-ESKYICTKIH 335
V P I SP T+ +P G+PKP + W+ +G L+ + ++
Sbjct: 3759 RVLEPPAIA--PSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLL 3816
Query: 336 VTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEK--QISAH 377
+N L L P ++ + + NE G+ + Q++ H
Sbjct: 3817 PSN------ALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVH 3854
Score = 52.4 bits (124), Expect = 1e-06
Identities = 52/191 (27%), Positives = 77/191 (40%), Gaps = 22/191 (11%)
Query: 206 LTVEEGKSITLSCSVAGDPVPNMYW--DVGNLVSKHMNETSHTQGSLRITNISSDDSGKQ 263
+ V +G++ L C+V G P P + W D L + S L++ + +G
Sbjct: 2455 IKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAG-H 2513
Query: 264 ISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHHWCIPFTVKGN----------PKP 313
SC+A N VGE L+V APTI ++D + TV P P
Sbjct: 2514 YSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEE--VTVTVNNPISLICEALAFPSP 2571
Query: 314 ALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQ 373
+ W +GA S+ I + T HG LQ+ N + G YT + NE G+ K
Sbjct: 2572 NITWMKDGAPFEASR----NIQLLPGT--HG-LQILNAQKEDAGQYTCVVTNELGEAVKN 2624
Query: 374 ISAHFMGWPGI 384
+ P I
Sbjct: 2625 YHVEVLIPPSI 2635
Score = 52.0 bits (123), Expect = 1e-06
Identities = 54/202 (26%), Positives = 80/202 (39%), Gaps = 17/202 (8%)
Query: 179 ESSKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNL-VS 237
ES + + L L PN N A V E S+TL C +G P P++ W G+ VS
Sbjct: 1873 ESKREVALKVLVPPNIEPGPVNKA-----VLENASVTLECLASGVPPPDVSWFKGHQPVS 1927
Query: 238 KHMNETSHTQGS-LRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPT 296
M T G LRI D+G CVA N+ G + L V+ P IT S
Sbjct: 1928 SWMGVTVSVDGRVLRIEQAQLSDAG-SYRCVASNVAGSTELRYGLRVNVPPRITLPPSLP 1986
Query: 297 SDHHWCIPF----TVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPT 352
P G P P L W +G ++ + ++ L L +
Sbjct: 1987 GPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRV-----LTLASAR 2041
Query: 353 HMNNGDYTLIAKNEYGKDEKQI 374
++G Y+ +A + G+D + +
Sbjct: 2042 ASDSGRYSCVAVSAVGEDRQDV 2063
Score = 51.6 bits (122), Expect = 2e-06
Identities = 51/171 (29%), Positives = 66/171 (38%), Gaps = 18/171 (10%)
Query: 211 GKSITLSCSVAGDPVPNMYWDVGNLV----SKHMNETSHTQGSLRITNISSDDSGKQISC 266
G + L C +G P P + W H+ Q LRIT D G+ C
Sbjct: 1423 GADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQ-VLRITGSHVGDEGR-YQC 1480
Query: 267 VAENLVGEDQDSVNLTVHFAPTI-----TFLESPTSDHHWCIPFTVKGNPKPALQWFYNG 321
VA + G+ L VH PTI T + DH + +G P P + WF +G
Sbjct: 1481 VAFSPAGQQARDFQLRVHAPPTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWFKDG 1540
Query: 322 AILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEK 372
A+L S TK+ T LQL + G YT A N G EK
Sbjct: 1541 ALLPTS----TKVVYTRGGRQ---LQLGRAQSSDAGVYTCKASNAVGAAEK 1584
Score = 51.6 bits (122), Expect = 2e-06
Identities = 53/202 (26%), Positives = 85/202 (42%), Gaps = 29/202 (14%)
Query: 206 LTVEEGKSITLSCSVAGDPVPNMYW-DVGNLVSKHMNETSHTQG-SLRITNISSDDSGKQ 263
+T G+ + L C +G PVP + W G + +QG +L I ++ D SG
Sbjct: 1699 VTTIVGQPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGTTLHIDHVELDHSG-L 1757
Query: 264 ISCVAENLVGEDQDSVNLTVH--FAPTITFLESPTSDHHW-----------CIPFTVKG- 309
+C A N G V ++VH +AP + LE P +HW C P +G
Sbjct: 1758 FACQATNEAGTAGAEVEVSVHGEWAPGV--LEVPIGQYHWGXEHHSSFPAACDPPVHRGW 1815
Query: 310 --NPKPAL--QWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKN 365
+PKP L W G++ E I + LQ++ + G YT A N
Sbjct: 1816 GAHPKPPLVEGWCSPGSLWGEPTGIPVAYSLPPP------LQIEKVDLRDEGIYTCAATN 1869
Query: 366 EYGKDEKQISAHFMGWPGIDDG 387
G+ +++++ + P I+ G
Sbjct: 1870 LAGESKREVALKVLVPPNIEPG 1891
Score = 51.2 bits (121), Expect = 2e-06
Identities = 43/169 (25%), Positives = 68/169 (40%), Gaps = 15/169 (8%)
Query: 211 GKSITLSCSVAGDPVPNMYWDVGNLVSKHMNETSHTQGSLRITNISSDDSGKQISCVAEN 270
G + L C+ G P P + W V + +L+ +S +DSG + C AEN
Sbjct: 4143 GDRLWLRCAARGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYV-CWAEN 4201
Query: 271 LVGEDQDSVNLTVHFAPTI-----TFLESPTSDHHWCIPFTVKGNPKPALQWFYNGAILN 325
VG Q + V AP + ++L P + V+G+P P + W +G L
Sbjct: 4202 RVGRTQAVSFVHVKEAPVLQGEAFSYLVEPVGGSIQ-LDCVVRGDPVPDIHWIKDGLPLR 4260
Query: 326 ESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQI 374
S H +G L + + G Y +A+NE G +K +
Sbjct: 4261 GSHL--------RHQLQNGSLTIHRTERDDAGRYQCLAENEMGVAKKVV 4301
Score = 50.8 bits (120), Expect = 3e-06
Identities = 44/187 (23%), Positives = 69/187 (36%), Gaps = 18/187 (9%)
Query: 206 LTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHMNETSHTQGSLRITNISSDDSGKQIS 265
L++ G + L C G P PN+ W + S LR+ D+G +
Sbjct: 3505 LSLTPGAPMELLCDAQGTPQPNITWHKDGQALTRLENNSRATRVLRVR-----DAG-LYT 3558
Query: 266 CVAENLVGEDQDSVNLTVHFAPTITFLESP-----TSDHHWCIPFTVKGNPKPALQWFYN 320
C+AE+ G + S + V P I P + + +V+ P P + W +
Sbjct: 3559 CLAESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAPKITWHRD 3618
Query: 321 GAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQISAHFMG 380
G +L E + T E LQL + ++GDY+ A+N G
Sbjct: 3619 GIVLQEDAH-------TQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHT 3671
Query: 381 WPGIDDG 387
P I G
Sbjct: 3672 VPTIRSG 3678
Score = 50.4 bits (119), Expect = 4e-06
Identities = 48/189 (25%), Positives = 83/189 (43%), Gaps = 21/189 (11%)
Query: 208 VEEGKSITLSCSVAGDPVPNMYWDV-GNLVSKHMNETSHTQG-SLRITNISSDDSGKQIS 265
V++G + TL C+ G P P + W+ G V + QG SL + + +G+ S
Sbjct: 2271 VQDGVA-TLECNATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRY-S 2328
Query: 266 CVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHHWCI--PFTV----KGNPKPALQWFY 319
CVAENL G + L+V P + P ++ + P T+ G P PA++WF
Sbjct: 2329 CVAENLAGRAERKFELSVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFR 2388
Query: 320 NGAILN--ESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQISAH 377
++ E Y+ + L++ ++G Y+ +A NE G+ + S
Sbjct: 2389 GEEPVSPGEDTYLLAGGWM---------LKMTQTQEQDSGLYSCLASNEAGEARRNFSVE 2439
Query: 378 FMGWPGIDD 386
+ P I++
Sbjct: 2440 VLVPPSIEN 2448
Score = 50.4 bits (119), Expect = 4e-06
Identities = 54/196 (27%), Positives = 77/196 (39%), Gaps = 25/196 (12%)
Query: 205 NLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHMNETSHTQGS--LRITNISSDDSGK 262
N+T +TL C G P P + W G +T G L++T DSG
Sbjct: 2361 NITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSG- 2419
Query: 263 QISCVAENLVGEDQDSVNLTVHFAPT---------ITFLESPTSDHHWCIPFTVKGNPKP 313
SC+A N GE + + ++ V P+ I L+ T+ H C V G+P+P
Sbjct: 2420 LYSCLASNEAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTA-HLMC---NVTGHPQP 2475
Query: 314 ALQWFYNGAILNESKYICTKIHVTNHTEYHG-CLQLDNPTHMNNGDYTLIAKNEYGKDEK 372
L WF +G L +H G LQ+ + G Y+ IA N G+ K
Sbjct: 2476 KLTWFKDGRPLARGD--------AHHISPDGVLLQVLQANLSSAGHYSCIAANAVGEKTK 2527
Query: 373 QISAHFMGWPGIDDGA 388
+ P I GA
Sbjct: 2528 HFQLSVLLAPTILGGA 2543
Score = 50.1 bits (118), Expect = 5e-06
Identities = 45/187 (24%), Positives = 77/187 (41%), Gaps = 15/187 (8%)
Query: 211 GKSITLSCSVAGDPVPNMYW--DVGNLVSKHMNETSHTQGSLRITNISSDDSGKQISCVA 268
G + L+C V+G P P + W D + S ++ G L+++ + +G +CVA
Sbjct: 3139 GSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAG-TYTCVA 3197
Query: 269 ENLVGEDQDSVNLTVHFAPTITFLESPTSDHHWC------IPFTVKGNPKPALQWFYNGA 322
EN E + + V AP I +HH + G P P + W +G+
Sbjct: 3198 ENTQAEARKDFVVAVLVAPRIR-SSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGS 3256
Query: 323 ILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQISAHFMGWP 382
L + + ++ G L L + G YT +A N G+D + + + + P
Sbjct: 3257 PLGQDMGPHLRFYLDG-----GSLVLKGLRASDAGAYTCVAHNPAGEDARLHTVNVLVPP 3311
Query: 383 GIDDGAN 389
I GA+
Sbjct: 3312 TIKQGAD 3318
Score = 49.7 bits (117), Expect = 7e-06
Identities = 44/178 (24%), Positives = 73/178 (41%), Gaps = 20/178 (11%)
Query: 206 LTVEEGKSITLSCSVAGDPVPNMYWDVGNL---VSKHMNETSHTQGSLRITNISSDDSGK 262
+TV +++L C G+PVP + W L S + Q L+++ D+
Sbjct: 2855 VTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQ-VLQVSTAEVADAAS 2913
Query: 263 QISCVAENLVGEDQDSVNLTVHFAPTITFLE----SPTSDHHWCIPFTVKGNPKPALQWF 318
+ CVAEN G + L V P I L+ + + +P V +P P + W+
Sbjct: 2914 YM-CVAENQAGSAEKLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWY 2972
Query: 319 YNGAILN--ESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQI 374
+ L+ E ++ H LQL ++G YT A N G+D+K +
Sbjct: 2973 KDSQALSLGEEVFLLPGTHT---------LQLGRARLSDSGMYTCEALNAAGRDQKLV 3021
Score = 48.9 bits (115), Expect = 1e-05
Identities = 51/193 (26%), Positives = 79/193 (40%), Gaps = 19/193 (9%)
Query: 206 LTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHMNETSHTQGSLRITNISSDDSGKQIS 265
L V G+++ L+C G+P P + W +V + QGS+ I + D+G+
Sbjct: 1129 LKVLVGEALDLNCVAEGNPEPQLSWSKDGVVLQGRG----PQGSVHFAAIRTSDAGR-YR 1183
Query: 266 CVAENLVGEDQDSVNLTVHFAP------TITFLESPTSDHHWCIPFTVKGNPKPALQWFY 319
C A N G D V L V P T LE ++ +P +G PKP + W
Sbjct: 1184 CEASNSAGVDAWEVELRVLEPPHWGADETSGLLERVAGENA-SLPCPARGTPKPQVTWRK 1242
Query: 320 NGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQISAHFM 379
+ +E + + V G L L + + ++GDY A NE G ++
Sbjct: 1243 GPS--SEPLHGQPGVAVLE----EGSLFLASVSPADSGDYECQATNEVGSTSRRAKLVVY 1296
Query: 380 GWPGI-DDGANPN 391
P I +DG N
Sbjct: 1297 VPPSIREDGRKAN 1309
Score = 48.9 bits (115), Expect = 1e-05
Identities = 45/182 (24%), Positives = 68/182 (37%), Gaps = 15/182 (8%)
Query: 211 GKSITLSCSVAGDPVPNMYWDVGNLVSKHMNETS-HTQGSLRITNISSDDSGKQISCVAE 269
G+ + L C G P P + W L NE+ T GS+ + S SCVA
Sbjct: 1611 GRPVALECVARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVAS 1670
Query: 270 NLVGEDQDSVNLTVHFAPTITFLE-----SPTSDHHWCIPFTVKGNPKPALQWFYNGAIL 324
+ GE ++ V P + E + +P G+P P +QW NG
Sbjct: 1671 SPAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNGRPA 1730
Query: 325 NESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGK--DEKQISAHFMGWP 382
E + T L +D+ ++G + A NE G E ++S H P
Sbjct: 1731 EELAGVQVASQGTT-------LHIDHVELDHSGLFACQATNEAGTAGAEVEVSVHGEWAP 1783
Query: 383 GI 384
G+
Sbjct: 1784 GV 1785
Score = 45.8 bits (107), Expect = 1e-04
Identities = 56/253 (22%), Positives = 100/253 (39%), Gaps = 41/253 (16%)
Query: 147 GNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLN---ESSKNIPLANLQIPNCGLPSANLAA 203
G+ S D + ++ LQ SS N E +K+ L+ L P + + A
Sbjct: 2489 GDAHHISPDGVLLQVLQANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSAD 2548
Query: 204 PNLTVEEGKSITLSCSVAGDPVPNMYWDVGNL---VSKHMNETSHTQGSLRITNISSDDS 260
+TV I+L C P PN+ W S+++ T G L+I N +D+
Sbjct: 2549 EEVTVTVNNPISLICEALAFPSPNITWMKDGAPFEASRNIQLLPGTHG-LQILNAQKEDA 2607
Query: 261 GKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSD------------------HHWC 302
G Q +CV N +GE + ++ V P+I+ + P + W
Sbjct: 2608 G-QYTCVVTNELGEAVKNYHVEVLIPPSIS-KDDPLGEVGVKEVKTKVNSTLTLECESWA 2665
Query: 303 IPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLI 362
+ P P ++W+ +G + S +++ V LQ+ ++G Y +
Sbjct: 2666 V-------PPPTIRWYKDGQPVTPS----SRLQVLGEGR---LLQIQPTQVSDSGRYLCV 2711
Query: 363 AKNEYGKDEKQIS 375
A N G+D++ +
Sbjct: 2712 ATNVAGEDDQDFN 2724
Score = 45.4 bits (106), Expect = 1e-04
Identities = 48/207 (23%), Positives = 74/207 (35%), Gaps = 33/207 (15%)
Query: 187 ANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGN--------LVSK 238
A +Q+ P ++TVE G+S L+C G P P + W G+ +
Sbjct: 776 AEIQLAVGHAPQLTELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGR 835
Query: 239 HMNETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTV---------HFAPTI 289
G L +++ +D + C A N+ G+ Q L V APT+
Sbjct: 836 GSRSRQPDSGVLFFESVAPEDQAPYV-CEARNVFGKVQAEARLIVTGHAPPQIASSAPTV 894
Query: 290 TFLE-SPTSDHHWCIP-FTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQ 347
LE P S +P + G P P W +G L + G L
Sbjct: 895 RVLEGQPVS-----LPCIVLAGRPLPERHWLKDGRPLPPGS--------RHSIRADGSLH 941
Query: 348 LDNPTHMNNGDYTLIAKNEYGKDEKQI 374
LD + G Y+ +A N G + +
Sbjct: 942 LDRALQEHAGRYSCVATNTAGSQHRDV 968
Score = 45.4 bits (106), Expect = 1e-04
Identities = 53/210 (25%), Positives = 90/210 (42%), Gaps = 27/210 (12%)
Query: 179 ESSKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYW-----DVG 233
E+ K+ +A L P + S+ +A + V EG+ + L C G P P++ W +G
Sbjct: 3203 EARKDFVVAVLVAPR--IRSSGVAREH-HVLEGQEVRLDCEADGQPPPDVAWLKDGSPLG 3259
Query: 234 NLVSKHMNETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTI---- 289
+ H+ GSL + + + D+G +CVA N GED + V PTI
Sbjct: 3260 QDMGPHL-RFYLDGGSLVLKGLRASDAG-AYTCVAHNPAGEDARLHTVNVLVPPTIKQGA 3317
Query: 290 ----TFLESPTSDHHWCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGC 345
T + P P V+G+P + W +G L S+ T +H + HT
Sbjct: 3318 DGSGTLVSRPGELVTMVCP--VRGSPPIHVSWLKDGLPLPLSQR--TLLHGSGHT----- 3368
Query: 346 LQLDNPTHMNNGDYTLIAKNEYGKDEKQIS 375
L++ + G +T +A + G ++ +
Sbjct: 3369 LRISKVQLADAGIFTCVAASPAGVADRNFT 3398
Score = 45.1 bits (105), Expect = 2e-04
Identities = 29/113 (25%), Positives = 46/113 (40%), Gaps = 2/113 (1%)
Query: 176 CLNESSKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYW-DVGN 234
CL E+ + + + P + ++TV G + L C G+P P + W G
Sbjct: 4288 CLAENEMGVAKKVVILVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQ 4347
Query: 235 LVSKHMNETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAP 287
+ + GSL + N+ + D+G CVA NL+G L V P
Sbjct: 4348 PLRASRRLRTLPDGSLWLENVETGDAG-TYDCVAHNLLGSATARAFLVVRGEP 4399
Score = 44.7 bits (104), Expect = 2e-04
Identities = 47/187 (25%), Positives = 71/187 (37%), Gaps = 19/187 (10%)
Query: 197 PSANLAAPNLTVEEGKSITLSCSVAGDPVPNM-YWDVGNLVSKHMNETSHT---QGSLRI 252
P+ + NLT+ L C +G P P + +W G + + + ++ +L +
Sbjct: 3764 PAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLL 3823
Query: 253 TNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESP---TSDHHWCIPFTVKG 309
T DS Q CV N VGE +TVH PTI ++ T + G
Sbjct: 3824 TAPGPQDSA-QFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTG 3882
Query: 310 NPKPALQWFYNGAILNE--SKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEY 367
P P + W GA L S Y G L++ ++ G YT A+N
Sbjct: 3883 IPAPTVSWSKAGAQLGARGSGY---------RVSPSGALEIGQALPIHAGRYTCSARNSA 3933
Query: 368 GKDEKQI 374
G K +
Sbjct: 3934 GVAHKHV 3940
Score = 44.7 bits (104), Expect = 2e-04
Identities = 42/169 (24%), Positives = 69/169 (40%), Gaps = 14/169 (8%)
Query: 205 NLTVEEGKSITLSCSVAGDPVPNMYWDVGN--LVSKHMNETSHTQGSLRITNISSDDSGK 262
+ TV + L+C G P P + W L ++ G+L I +G+
Sbjct: 3865 DFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGR 3924
Query: 263 QISCVAENLVGEDQDSVNLTVHFAPTITFLES---PTSDHHWCIPFTVKGNPKPALQWFY 319
+C A N G V LTV +P + L S ++ +P G P+P + W
Sbjct: 3925 Y-TCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQK 3983
Query: 320 NGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYG 368
G LN + + T++ G L++ + + + G+Y IAKN G
Sbjct: 3984 EG--LNVATGVSTQVLP------GGQLRIAHASPEDAGNYLCIAKNSAG 4024
Score = 44.3 bits (103), Expect = 3e-04
Identities = 46/192 (23%), Positives = 75/192 (39%), Gaps = 19/192 (9%)
Query: 206 LTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHMNETS-HTQG-SLRITNISSDDSGKQ 263
L G+ +T+ C V G P ++ W L T H G +LRI+ + D+G
Sbjct: 3323 LVSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGI- 3381
Query: 264 ISCVAENLVGEDQDSVNLTVHFAPTITFLESPTS-----DHHWCIPFTVKGNPKPALQWF 318
+CVA + G + L V P + +E +P +G P P + W
Sbjct: 3382 FTCVAASPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWM 3441
Query: 319 YNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQISAHF 378
+G L ++ E LQL+ ++G Y+ +A +E G+ +
Sbjct: 3442 KDGEPL-----------LSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTV 3490
Query: 379 MGWPGIDDGANP 390
M P I+D P
Sbjct: 3491 MEPPHIEDSGQP 3502
Score = 43.9 bits (102), Expect = 4e-04
Identities = 41/194 (21%), Positives = 70/194 (36%), Gaps = 16/194 (8%)
Query: 206 LTVEEGKSITLSCSVAGDPVPNMYW-DVGNLVSKHMNETSHTQGSLRITNISSDDSGKQ- 263
LTV EG +LSC G P P + W G + H R+ + ++
Sbjct: 2172 LTVREGHPTSLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEG 2231
Query: 264 -ISCVAENLVGEDQDSVNLTVHFAPTITFLESP------TSDHHWCIPFTVKGNPKPALQ 316
+C N+VG + L VH P I P D + G P P +
Sbjct: 2232 TYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPTVT 2291
Query: 317 WFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQISA 376
W +G + + + N + L ++ + G Y+ +A+N G+ E++
Sbjct: 2292 WERDGQPVGAE----LGLQLQNQGQ---SLHVERAQAAHTGRYSCVAENLAGRAERKFEL 2344
Query: 377 HFMGWPGIDDGANP 390
+ P + +P
Sbjct: 2345 SVLVPPELIGDLDP 2358
Score = 42.4 bits (98), Expect = 0.001
Identities = 34/124 (27%), Positives = 49/124 (39%), Gaps = 5/124 (4%)
Query: 197 PSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHMNETSHTQGSLRITNIS 256
PS + + V G+ L C +G P P + W G L E S + G LRI
Sbjct: 698 PSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYRGGLEMILAPEGS-SSGKLRIPAAQ 756
Query: 257 SDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTS---DHHWCIPFTVKGNPKP 313
D+G +C A N +G+ + L V AP +T L + + G P P
Sbjct: 757 ERDAG-TYTCRAVNELGDASAEIQLAVGHAPQLTELPRDVTVELGRSALLACRATGRPPP 815
Query: 314 ALQW 317
+ W
Sbjct: 816 TVTW 819
Score = 42.4 bits (98), Expect = 0.001
Identities = 56/226 (24%), Positives = 77/226 (34%), Gaps = 25/226 (11%)
Query: 161 TLQEAKSSPDTQDLY---CLNESSKNIPLANLQIPNCGLPSANLAAPN-----LTVEEGK 212
TLQ ++ +Y LN + ++ L L + +P A AP + V G
Sbjct: 2992 TLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVL---VPPAFRQAPRGPQDAVLVRVGD 3048
Query: 213 SITLSCSVAGDPVPNMYW--DVGNLVSKHMNETSHTQGSLRITNISSDDSGKQISCVAEN 270
LSC P P + W D LV + L I D G SC N
Sbjct: 3049 KAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLY-SCKVSN 3107
Query: 271 LVGEDQDSVNLTVHFAPTI----TFLESPTSDHHWCIPFTVKGNPKPALQWFYNGAILNE 326
+ GE + LTV PT T S + + V G P P + W + +
Sbjct: 3108 VAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVES 3167
Query: 327 SKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEK 372
S V G LQL G YT +A+N + K
Sbjct: 3168 SA-------VHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAEARK 3206
Score = 42.4 bits (98), Expect = 0.001
Identities = 47/195 (24%), Positives = 77/195 (39%), Gaps = 26/195 (13%)
Query: 205 NLTVEEGKSITLSCSVAGDPVPNMYW--DVGNLVSKHMNETSHTQGSLRITNISSDDSGK 262
++ V G + L C G P+P + W D L+S+ + + SL++ + + DSG
Sbjct: 3415 DVVVVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQSLEQGP----SLQLEAVGAGDSG- 3469
Query: 263 QISCVAENLVGEDQDSVNLTVHFAPTITFLESPTS-----DHHWCIPFTVKGNPKPALQW 317
SCVA + GE + LTV P I PT + +G P+P + W
Sbjct: 3470 TYSCVAVSEAGEARRHFQLTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITW 3529
Query: 318 FYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQISAH 377
+G L + N++ L++ + G YT +A++ G EK
Sbjct: 3530 HKDGQALT---------RLENNSRATRVLRV-----RDAGLYTCLAESPAGAIEKSFRVR 3575
Query: 378 FMGWPGIDDGANPNY 392
P I P +
Sbjct: 3576 VQAPPNIVGPRGPRF 3590
Score = 42.0 bits (97), Expect = 0.001
Identities = 44/174 (25%), Positives = 69/174 (39%), Gaps = 17/174 (9%)
Query: 208 VEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHMNETSHTQGS--LRITNISSDDSGKQIS 265
+ E L C P P++ W + +E S QG L+I + ++++G+ S
Sbjct: 2762 IVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRY-S 2820
Query: 266 CVAENLVGEDQDSVNLTVHFAPTI-----TFLESPTSDHHWCIPF--TVKGNPKPALQWF 318
C A N VGED L V P I +E T + + GNP P + W
Sbjct: 2821 CKASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPVPTISWL 2880
Query: 319 YNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEK 372
NG + S ++ V + LQ+ + Y +A+N+ G EK
Sbjct: 2881 QNGLPFSPS----PRLQVLEDGQ---VLQVSTAEVADAASYMCVAENQAGSAEK 2927
Score = 40.0 bits (92), Expect = 0.006
Identities = 27/98 (27%), Positives = 45/98 (45%), Gaps = 7/98 (7%)
Query: 189 LQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYW--DVGNLVSKHMNETSHT 246
+Q+P P + A + EG +L C +G P P + W + L S+ +
Sbjct: 972 VQVP----PRIHPTATHHITNEGVPASLPCVASGVPAPTITWTKETNALTSRGPHYNVSK 1027
Query: 247 QGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVH 284
+G+L I S+ D+G + C A N VG + L+V+
Sbjct: 1028 EGTLLIAQPSAQDAGAYV-CTATNTVGFSSQEMRLSVN 1064
Score = 40.0 bits (92), Expect = 0.006
Identities = 42/176 (23%), Positives = 61/176 (34%), Gaps = 12/176 (6%)
Query: 205 NLTVEEGKSITLSCSVAGDPVPNMYW--DVGNLVSKHMNETSHTQGSLRITNISSDDSGK 262
N++V +S+ L C P P + W D L + S + L++ D+G
Sbjct: 2079 NVSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVWDAG- 2137
Query: 263 QISCVAENLVGEDQDSVNLTVHFAPTITFLESPT----SDHHWCIPFTVKGNPKPALQWF 318
+C A N G + NL V AP ES T H + +G P P + W
Sbjct: 2138 HYTCEALNQAGHSEKHYNLNVWVAPVFPLRESHTLTVREGHPTSLSCECRGVPFPKISWR 2197
Query: 319 YNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQI 374
+G L + Y G QL G YT N G + +
Sbjct: 2198 KDGQPLPGEGAGLQHVSAVGRLLYLGQAQL-----AQEGTYTCECSNVVGNSSQDL 2248
Score = 34.7 bits (78), Expect = 0.23
Identities = 30/115 (26%), Positives = 47/115 (40%), Gaps = 5/115 (4%)
Query: 177 LNESSKNIPLANLQIPNCGL--PSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYW-DVG 233
L E+ KN + L P+ P + + + ++TL C P P + W G
Sbjct: 2618 LGEAVKNYHVEVLIPPSISKDDPLGEVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDG 2677
Query: 234 NLVSKHMNETSHTQGSL-RITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAP 287
V+ +G L +I DSG+ + CVA N+ GED N+ + P
Sbjct: 2678 QPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYL-CVATNVAGEDDQDFNVLIQVPP 2731
Score = 32.7 bits (73), Expect = 0.89
Identities = 31/104 (29%), Positives = 40/104 (38%), Gaps = 22/104 (21%)
Query: 205 NLTVEEGKSITLSCSVAGDPVPNMYW------------------DVG-NLVSKHMNETSH 245
N++ G+S+TL C G PVP + W D+G V H
Sbjct: 1309 NVSGMAGQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGH--RLLD 1366
Query: 246 TQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTI 289
SL I DSG SC AEN G Q +L V P++
Sbjct: 1367 EGQSLHFPRIQEGDSGLY-SCRAENQAGTAQRDFHLLVLTPPSV 1409
Score = 32.3 bits (72), Expect = 1.2
Identities = 32/134 (23%), Positives = 49/134 (36%), Gaps = 14/134 (10%)
Query: 199 ANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHMNETSHTQG--SLRITNIS 256
A L +T S++L C V P P + W + E G +L++
Sbjct: 2940 AGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRAR 2999
Query: 257 SDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDH---------HWCIPFTV 307
DSG +C A N G DQ V L+V P F ++P +
Sbjct: 3000 LSDSG-MYTCEALNAAGRDQKLVQLSVLVPP--AFRQAPRGPQDAVLVRVGDKAVLSCET 3056
Query: 308 KGNPKPALQWFYNG 321
P+P + W+ +G
Sbjct: 3057 DALPEPTVTWYKDG 3070
>gi|239743951 PREDICTED: hypothetical protein XP_002342997 [Homo
sapiens]
Length = 790
Score = 68.9 bits (167), Expect = 1e-11
Identities = 64/231 (27%), Positives = 94/231 (40%), Gaps = 22/231 (9%)
Query: 162 LQEAKSSPDTQDLYCLNESSKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVA 221
L+ +K+ T + C S A QI P + APN+TV G++ LSC V
Sbjct: 483 LRASKAEEGTYE--CTAVSRAGTGRAKAQIVVTDPPPQLVPAPNVTVSPGETAVLSCRVL 540
Query: 222 GDPVPNMYW--DVGNLVSKHMNETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSV 279
G+ N+ W D L + SL I+ I D G+ CVA N G + SV
Sbjct: 541 GEAPYNLTWVRDWRVLPASTGRVAQLADLSLEISGIIPTDGGR-YQCVASNANGVTRASV 599
Query: 280 NLTVHFAPTITFLESPTSDHHWCIPFTVK------GNPKPALQWFYNGAILNESKYICTK 333
L V AP ++ TS H+ VK G P P + W L E I
Sbjct: 600 WLLVREAPQVSI---HTSSQHFSQGVEVKVSCSASGYPTPHISWSRESQALQEDSRI--- 653
Query: 334 IHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQISAHFMGWPGI 384
H + G L + + G+Y+ A NE G D++ ++ ++ P +
Sbjct: 654 -----HVDAQGTLIIQGVAPEDAGNYSCQATNEVGTDQETVTLYYTDPPSV 699
Score = 53.5 bits (127), Expect = 5e-07
Identities = 46/206 (22%), Positives = 87/206 (42%), Gaps = 21/206 (10%)
Query: 176 CLNESSKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNL 235
C+ ++ + A++ + P ++ + +G + +SCS +G P P++ W +
Sbjct: 586 CVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISW---SR 642
Query: 236 VSKHMNETSH----TQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITF 291
S+ + E S QG+L I ++ +D+G SC A N VG DQ++V L P+++
Sbjct: 643 ESQALQEDSRIHVDAQGTLIIQGVAPEDAGNY-SCQATNEVGTDQETVTLYYTDPPSVSA 701
Query: 292 LES---PTSDHHWCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQL 348
+ + + G P P + W+ G ++ + G L++
Sbjct: 702 VNAVVLVAVGEEAVLVCEASGVPPPRVIWYRGG----------LEMILAPEGSSSGKLRI 751
Query: 349 DNPTHMNNGDYTLIAKNEYGKDEKQI 374
+ G YT A NE G +I
Sbjct: 752 PAAQERDAGTYTCRAVNELGDASAEI 777
Score = 34.7 bits (78), Expect = 0.23
Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 2/87 (2%)
Query: 197 PSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHMNETSHTQGSLRITNIS 256
PS + + V G+ L C +G P P + W G L E S + G LRI
Sbjct: 697 PSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYRGGLEMILAPEGS-SSGKLRIPAAQ 755
Query: 257 SDDSGKQISCVAENLVGEDQDSVNLTV 283
D+G +C A N +G+ + L V
Sbjct: 756 ERDAG-TYTCRAVNELGDASAEIQLAV 781
>gi|7662320 leucine-rich repeats and immunoglobulin-like domains 2
[Homo sapiens]
Length = 1065
Score = 67.4 bits (163), Expect = 3e-11
Identities = 64/286 (22%), Positives = 115/286 (40%), Gaps = 39/286 (13%)
Query: 72 FIANQKRLEIIN-------EDDVEAYVGLRNLT---IVDSGLKFVAHKAFLKNSNLQHIN 121
F++N + L++ N ED EA+ GL +LT + + +K + KAF+ +L+H++
Sbjct: 357 FLSNLQTLDLRNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSITKKAFIGLESLEHLD 416
Query: 122 FTRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWI------KTLQEAKSSPDTQDLY 175
N + S+ F L ELIL + C C + W+ Q + + +
Sbjct: 417 LNNNAIMSIQENAFSQTHLKELILNTSSLLCDCHLKWLLQWLVDNNFQHSVNVSCAHPEW 476
Query: 176 CLNESSKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSV--AGDPVPNMYW--- 230
+S N+ L + + P + G ++TL+C+ + D + W
Sbjct: 477 LAGQSILNVDLKDFVCDDFLKPQIRTHPETIIALRGMNVTLTCTAVSSSDSPMSTVWRKD 536
Query: 231 -------DVGNLVS--KHMNETSHTQGSLRITNISSDDSGKQISCVAENLVGED-QDSVN 280
D N V + E L + N++ D GK C+ N G +
Sbjct: 537 SEILYDVDTENFVRYWQQAGEALEYTSILHLFNVNFTDEGK-YQCIVTNHFGSNYSQKAK 595
Query: 281 LTVHFAPTITFLESP-----TSDHHWCIPFTVKGNPKPALQWFYNG 321
LTV+ P +FL++P + + +G+P P + W +G
Sbjct: 596 LTVNEMP--SFLKTPMDLTIRTGAMARLECAAEGHPAPQISWQKDG 639
Score = 41.2 bits (95), Expect = 0.003
Identities = 28/114 (24%), Positives = 50/114 (43%), Gaps = 3/114 (2%)
Query: 176 CLNESSKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYW--DVG 233
C+ +++ AN + PS + TV G++ L C G P P + W D G
Sbjct: 675 CMAQNTAGGLSANASLTVLETPSFIRPLEDKTVTRGETAVLQCIAGGSPAPRLNWTKDDG 734
Query: 234 NLVSKHMNETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAP 287
L+ + + L I + +D+GK +C+ N +G ++ + L V +P
Sbjct: 735 PLLVTERHFFAAANQLLIIVDAGLEDAGK-YTCIMSNTLGTERGHIYLNVISSP 787
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 67.0 bits (162), Expect = 4e-11
Identities = 58/223 (26%), Positives = 91/223 (40%), Gaps = 18/223 (8%)
Query: 162 LQEAKSSPDTQDLY-CLNESSKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSV 220
L+ A +SP+ Y C+ ++S + ++ P P+L+ EG L C
Sbjct: 2811 LRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKA 2870
Query: 221 AGDPVPNMYWDV-GNLVSKHMNE-TSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDS 278
G P PN+ WD G VS + T G L + N+ D+G +C AEN VG +
Sbjct: 2871 RGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAG-TYTCTAENAVGRARRR 2929
Query: 279 VNLTVHFAPTITFLESPTS----DHHWCIPFTVKGNPKPALQWFYNGAILNESKYICTKI 334
V+LT+ P T L S D W + +G+P P + W N + E
Sbjct: 2930 VHLTILVLPVFTTLPGDRSLRLGDRLW-LRCAARGSPTPRIGWTVNDRPVTEG------- 2981
Query: 335 HVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQISAH 377
+ + LQ + ++G Y A+N G+ + H
Sbjct: 2982 --VSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVH 3022
Score = 57.8 bits (138), Expect = 3e-08
Identities = 50/164 (30%), Positives = 69/164 (42%), Gaps = 17/164 (10%)
Query: 211 GKSITLSCSVAGDPVPNMYWDVGNLVSKHMNETSHTQ-GSLRITNISSDDSGKQISCVAE 269
G SI L C V GDPVP+++W L + + Q GSL I DD+G+ C+AE
Sbjct: 3042 GGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGR-YQCLAE 3100
Query: 270 NLVGEDQDSVNLTVHFAPTITFLESP-----TSDHHWCIPFTVKGNPKPALQWFYNGAIL 324
N +G + V L + AP F P S + G P P ++W G L
Sbjct: 3101 NEMGVAKKVVILVLQSAP--VFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPL 3158
Query: 325 NESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYG 368
S+ + T G L L+N + G Y +A N G
Sbjct: 3159 RASRRL--------RTLPDGSLWLENVETGDAGTYDCVAHNLLG 3194
Score = 56.2 bits (134), Expect = 8e-08
Identities = 44/179 (24%), Positives = 76/179 (42%), Gaps = 18/179 (10%)
Query: 206 LTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHMNETSHTQG--SLRITNISSDDSGKQ 263
+ V E + L C G P PN+ W + + +T+G L++ S D+G
Sbjct: 321 VAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAG-V 379
Query: 264 ISCVAENLVGEDQDSVNLTVHFAPTI------TFLESPTSDHHWCIPFTVKGNPKPALQW 317
+C A N VG + + L V+ PTI ++ + + +G+P P L W
Sbjct: 380 YTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGHPSPTLSW 439
Query: 318 FYNGAILNESKYICTKIHVTNHTEYHG-CLQLDNPTHMNNGDYTLIAKNEYGKDEKQIS 375
+ G + ES + E G L+L++P ++G Y+ +A + G+ Q S
Sbjct: 440 HHEGLPVAESN--------ESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYS 490
Score = 55.5 bits (132), Expect = 1e-07
Identities = 49/166 (29%), Positives = 72/166 (43%), Gaps = 15/166 (9%)
Query: 214 ITLSCSVAGDPVPNMYW-DVGNLVSKHMNETSHTQGSLRITNISS---DDSGKQISCVAE 269
+ L+C+ G P P + W GN VS R+ ++S DSG+ SCVA
Sbjct: 804 VRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRY-SCVAV 862
Query: 270 NLVGEDQDSVNLTVHFAPTITFLE---SPTSDHHWCIPFTVKGNPKPALQWFYNGAILNE 326
+ VGED+ V L VH P+I E S ++ + P P L W+ +G L
Sbjct: 863 SAVGEDRQDVVLQVHMPPSILGEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPLEP 922
Query: 327 SKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEK 372
+H++ LQ+D + G YT A N+ G+ EK
Sbjct: 923 R----PGVHLSAD---KALLQVDRADVWDAGHYTCEALNQAGRSEK 961
Score = 52.8 bits (125), Expect = 8e-07
Identities = 52/224 (23%), Positives = 93/224 (41%), Gaps = 19/224 (8%)
Query: 164 EAKSSPDTQDLYCLNESSKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGD 223
+A S+ D+ D C ++ ++ +P+ P + V ++ L C G
Sbjct: 2449 QALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGV 2508
Query: 224 PVPNMYW--DVGNLVSKHMNETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNL 281
P P + W D L + +GSLRI + + D+G + C+A N G D+ +L
Sbjct: 2509 PAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYL-CLASNSAGSDRQGRDL 2567
Query: 282 TVHFAPTITFLESP-----TSDHHWCIPFTVKGNPKPALQWFYNGAILN-ESKYICTKIH 335
V P I SP T+ +P G+PKP + W+ +G L+ + ++
Sbjct: 2568 RVLEPPAIA--PSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLL 2625
Query: 336 VTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEK--QISAH 377
+N L L P ++ + + NE G+ + Q++ H
Sbjct: 2626 PSN------ALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVH 2663
Score = 52.4 bits (124), Expect = 1e-06
Identities = 52/191 (27%), Positives = 77/191 (40%), Gaps = 22/191 (11%)
Query: 206 LTVEEGKSITLSCSVAGDPVPNMYW--DVGNLVSKHMNETSHTQGSLRITNISSDDSGKQ 263
+ V +G++ L C+V G P P + W D L + S L++ + +G
Sbjct: 1264 IKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAG-H 1322
Query: 264 ISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHHWCIPFTVKGN----------PKP 313
SC+A N VGE L+V APTI ++D + TV P P
Sbjct: 1323 YSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEE--VTVTVNNPISLICEALAFPSP 1380
Query: 314 ALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQ 373
+ W +GA S+ I + T HG LQ+ N + G YT + NE G+ K
Sbjct: 1381 NITWMKDGAPFEASR----NIQLLPGT--HG-LQILNAQKEDAGQYTCVVTNELGEAVKN 1433
Query: 374 ISAHFMGWPGI 384
+ P I
Sbjct: 1434 YHVEVLIPPSI 1444
Score = 52.0 bits (123), Expect = 1e-06
Identities = 54/202 (26%), Positives = 80/202 (39%), Gaps = 17/202 (8%)
Query: 179 ESSKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNL-VS 237
ES + + L L PN N A V E S+TL C +G P P++ W G+ VS
Sbjct: 682 ESKREVALKVLVPPNIEPGPVNKA-----VLENASVTLECLASGVPPPDVSWFKGHQPVS 736
Query: 238 KHMNETSHTQGS-LRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPT 296
M T G LRI D+G CVA N+ G + L V+ P IT S
Sbjct: 737 SWMGVTVSVDGRVLRIEQAQLSDAG-SYRCVASNVAGSTELRYGLRVNVPPRITLPPSLP 795
Query: 297 SDHHWCIPF----TVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPT 352
P G P P L W +G ++ + ++ L L +
Sbjct: 796 GPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRV-----LTLASAR 850
Query: 353 HMNNGDYTLIAKNEYGKDEKQI 374
++G Y+ +A + G+D + +
Sbjct: 851 ASDSGRYSCVAVSAVGEDRQDV 872
Score = 51.6 bits (122), Expect = 2e-06
Identities = 51/171 (29%), Positives = 66/171 (38%), Gaps = 18/171 (10%)
Query: 211 GKSITLSCSVAGDPVPNMYWDVGNLV----SKHMNETSHTQGSLRITNISSDDSGKQISC 266
G + L C +G P P + W H+ Q LRIT D G+ C
Sbjct: 232 GADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQ-VLRITGSHVGDEGR-YQC 289
Query: 267 VAENLVGEDQDSVNLTVHFAPTI-----TFLESPTSDHHWCIPFTVKGNPKPALQWFYNG 321
VA + G+ L VH PTI T + DH + +G P P + WF +G
Sbjct: 290 VAFSPAGQQARDFQLRVHAPPTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWFKDG 349
Query: 322 AILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEK 372
A+L S TK+ T LQL + G YT A N G EK
Sbjct: 350 ALLPTS----TKVVYTRGGRQ---LQLGRAQSSDAGVYTCKASNAVGAAEK 393
Score = 51.6 bits (122), Expect = 2e-06
Identities = 53/202 (26%), Positives = 85/202 (42%), Gaps = 29/202 (14%)
Query: 206 LTVEEGKSITLSCSVAGDPVPNMYW-DVGNLVSKHMNETSHTQG-SLRITNISSDDSGKQ 263
+T G+ + L C +G PVP + W G + +QG +L I ++ D SG
Sbjct: 508 VTTIVGQPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGTTLHIDHVELDHSG-L 566
Query: 264 ISCVAENLVGEDQDSVNLTVH--FAPTITFLESPTSDHHW-----------CIPFTVKG- 309
+C A N G V ++VH +AP + LE P +HW C P +G
Sbjct: 567 FACQATNEAGTAGAEVEVSVHGEWAPGV--LEVPIGQYHWGXEHHSSFPAACDPPVHRGW 624
Query: 310 --NPKPAL--QWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKN 365
+PKP L W G++ E I + LQ++ + G YT A N
Sbjct: 625 GAHPKPPLVEGWCSPGSLWGEPTGIPVAYSLPPP------LQIEKVDLRDEGIYTCAATN 678
Query: 366 EYGKDEKQISAHFMGWPGIDDG 387
G+ +++++ + P I+ G
Sbjct: 679 LAGESKREVALKVLVPPNIEPG 700
Score = 51.2 bits (121), Expect = 2e-06
Identities = 43/169 (25%), Positives = 68/169 (40%), Gaps = 15/169 (8%)
Query: 211 GKSITLSCSVAGDPVPNMYWDVGNLVSKHMNETSHTQGSLRITNISSDDSGKQISCVAEN 270
G + L C+ G P P + W V + +L+ +S +DSG + C AEN
Sbjct: 2952 GDRLWLRCAARGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYV-CWAEN 3010
Query: 271 LVGEDQDSVNLTVHFAPTI-----TFLESPTSDHHWCIPFTVKGNPKPALQWFYNGAILN 325
VG Q + V AP + ++L P + V+G+P P + W +G L
Sbjct: 3011 RVGRTQAVSFVHVKEAPVLQGEAFSYLVEPVGGSIQ-LDCVVRGDPVPDIHWIKDGLPLR 3069
Query: 326 ESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQI 374
S H +G L + + G Y +A+NE G +K +
Sbjct: 3070 GSHL--------RHQLQNGSLTIHRTERDDAGRYQCLAENEMGVAKKVV 3110
Score = 50.8 bits (120), Expect = 3e-06
Identities = 44/187 (23%), Positives = 69/187 (36%), Gaps = 18/187 (9%)
Query: 206 LTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHMNETSHTQGSLRITNISSDDSGKQIS 265
L++ G + L C G P PN+ W + S LR+ D+G +
Sbjct: 2314 LSLTPGAPMELLCDAQGTPQPNITWHKDGQALTRLENNSRATRVLRVR-----DAG-LYT 2367
Query: 266 CVAENLVGEDQDSVNLTVHFAPTITFLESP-----TSDHHWCIPFTVKGNPKPALQWFYN 320
C+AE+ G + S + V P I P + + +V+ P P + W +
Sbjct: 2368 CLAESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAPKITWHRD 2427
Query: 321 GAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQISAHFMG 380
G +L E + T E LQL + ++GDY+ A+N G
Sbjct: 2428 GIVLQEDAH-------TQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHT 2480
Query: 381 WPGIDDG 387
P I G
Sbjct: 2481 VPTIRSG 2487
Score = 50.4 bits (119), Expect = 4e-06
Identities = 48/189 (25%), Positives = 83/189 (43%), Gaps = 21/189 (11%)
Query: 208 VEEGKSITLSCSVAGDPVPNMYWDV-GNLVSKHMNETSHTQG-SLRITNISSDDSGKQIS 265
V++G + TL C+ G P P + W+ G V + QG SL + + +G+ S
Sbjct: 1080 VQDGVA-TLECNATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRY-S 1137
Query: 266 CVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHHWCI--PFTV----KGNPKPALQWFY 319
CVAENL G + L+V P + P ++ + P T+ G P PA++WF
Sbjct: 1138 CVAENLAGRAERKFELSVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFR 1197
Query: 320 NGAILN--ESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQISAH 377
++ E Y+ + L++ ++G Y+ +A NE G+ + S
Sbjct: 1198 GEEPVSPGEDTYLLAGGWM---------LKMTQTQEQDSGLYSCLASNEAGEARRNFSVE 1248
Query: 378 FMGWPGIDD 386
+ P I++
Sbjct: 1249 VLVPPSIEN 1257
Score = 50.4 bits (119), Expect = 4e-06
Identities = 54/196 (27%), Positives = 77/196 (39%), Gaps = 25/196 (12%)
Query: 205 NLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHMNETSHTQGS--LRITNISSDDSGK 262
N+T +TL C G P P + W G +T G L++T DSG
Sbjct: 1170 NITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSG- 1228
Query: 263 QISCVAENLVGEDQDSVNLTVHFAPT---------ITFLESPTSDHHWCIPFTVKGNPKP 313
SC+A N GE + + ++ V P+ I L+ T+ H C V G+P+P
Sbjct: 1229 LYSCLASNEAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTA-HLMC---NVTGHPQP 1284
Query: 314 ALQWFYNGAILNESKYICTKIHVTNHTEYHG-CLQLDNPTHMNNGDYTLIAKNEYGKDEK 372
L WF +G L +H G LQ+ + G Y+ IA N G+ K
Sbjct: 1285 KLTWFKDGRPLARGD--------AHHISPDGVLLQVLQANLSSAGHYSCIAANAVGEKTK 1336
Query: 373 QISAHFMGWPGIDDGA 388
+ P I GA
Sbjct: 1337 HFQLSVLLAPTILGGA 1352
Score = 50.1 bits (118), Expect = 5e-06
Identities = 45/187 (24%), Positives = 77/187 (41%), Gaps = 15/187 (8%)
Query: 211 GKSITLSCSVAGDPVPNMYW--DVGNLVSKHMNETSHTQGSLRITNISSDDSGKQISCVA 268
G + L+C V+G P P + W D + S ++ G L+++ + +G +CVA
Sbjct: 1948 GSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAG-TYTCVA 2006
Query: 269 ENLVGEDQDSVNLTVHFAPTITFLESPTSDHHWC------IPFTVKGNPKPALQWFYNGA 322
EN E + + V AP I +HH + G P P + W +G+
Sbjct: 2007 ENTQAEARKDFVVAVLVAPRIR-SSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGS 2065
Query: 323 ILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQISAHFMGWP 382
L + + ++ G L L + G YT +A N G+D + + + + P
Sbjct: 2066 PLGQDMGPHLRFYLDG-----GSLVLKGLRASDAGAYTCVAHNPAGEDARLHTVNVLVPP 2120
Query: 383 GIDDGAN 389
I GA+
Sbjct: 2121 TIKQGAD 2127
Score = 49.7 bits (117), Expect = 7e-06
Identities = 44/178 (24%), Positives = 73/178 (41%), Gaps = 20/178 (11%)
Query: 206 LTVEEGKSITLSCSVAGDPVPNMYWDVGNL---VSKHMNETSHTQGSLRITNISSDDSGK 262
+TV +++L C G+PVP + W L S + Q L+++ D+
Sbjct: 1664 VTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQ-VLQVSTAEVADAAS 1722
Query: 263 QISCVAENLVGEDQDSVNLTVHFAPTITFLE----SPTSDHHWCIPFTVKGNPKPALQWF 318
+ CVAEN G + L V P I L+ + + +P V +P P + W+
Sbjct: 1723 YM-CVAENQAGSAEKLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWY 1781
Query: 319 YNGAILN--ESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQI 374
+ L+ E ++ H LQL ++G YT A N G+D+K +
Sbjct: 1782 KDSQALSLGEEVFLLPGTHT---------LQLGRARLSDSGMYTCEALNAAGRDQKLV 1830
Score = 48.9 bits (115), Expect = 1e-05
Identities = 45/182 (24%), Positives = 68/182 (37%), Gaps = 15/182 (8%)
Query: 211 GKSITLSCSVAGDPVPNMYWDVGNLVSKHMNETS-HTQGSLRITNISSDDSGKQISCVAE 269
G+ + L C G P P + W L NE+ T GS+ + S SCVA
Sbjct: 420 GRPVALECVARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVAS 479
Query: 270 NLVGEDQDSVNLTVHFAPTITFLE-----SPTSDHHWCIPFTVKGNPKPALQWFYNGAIL 324
+ GE ++ V P + E + +P G+P P +QW NG
Sbjct: 480 SPAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNGRPA 539
Query: 325 NESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGK--DEKQISAHFMGWP 382
E + T L +D+ ++G + A NE G E ++S H P
Sbjct: 540 EELAGVQVASQGTT-------LHIDHVELDHSGLFACQATNEAGTAGAEVEVSVHGEWAP 592
Query: 383 GI 384
G+
Sbjct: 593 GV 594
Score = 45.8 bits (107), Expect = 1e-04
Identities = 56/253 (22%), Positives = 100/253 (39%), Gaps = 41/253 (16%)
Query: 147 GNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLN---ESSKNIPLANLQIPNCGLPSANLAA 203
G+ S D + ++ LQ SS N E +K+ L+ L P + + A
Sbjct: 1298 GDAHHISPDGVLLQVLQANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSAD 1357
Query: 204 PNLTVEEGKSITLSCSVAGDPVPNMYWDVGNL---VSKHMNETSHTQGSLRITNISSDDS 260
+TV I+L C P PN+ W S+++ T G L+I N +D+
Sbjct: 1358 EEVTVTVNNPISLICEALAFPSPNITWMKDGAPFEASRNIQLLPGTHG-LQILNAQKEDA 1416
Query: 261 GKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSD------------------HHWC 302
G Q +CV N +GE + ++ V P+I+ + P + W
Sbjct: 1417 G-QYTCVVTNELGEAVKNYHVEVLIPPSIS-KDDPLGEVGVKEVKTKVNSTLTLECESWA 1474
Query: 303 IPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLI 362
+ P P ++W+ +G + S +++ V LQ+ ++G Y +
Sbjct: 1475 V-------PPPTIRWYKDGQPVTPS----SRLQVLGEGR---LLQIQPTQVSDSGRYLCV 1520
Query: 363 AKNEYGKDEKQIS 375
A N G+D++ +
Sbjct: 1521 ATNVAGEDDQDFN 1533
Score = 45.4 bits (106), Expect = 1e-04
Identities = 53/210 (25%), Positives = 90/210 (42%), Gaps = 27/210 (12%)
Query: 179 ESSKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYW-----DVG 233
E+ K+ +A L P + S+ +A + V EG+ + L C G P P++ W +G
Sbjct: 2012 EARKDFVVAVLVAPR--IRSSGVAREH-HVLEGQEVRLDCEADGQPPPDVAWLKDGSPLG 2068
Query: 234 NLVSKHMNETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTI---- 289
+ H+ GSL + + + D+G +CVA N GED + V PTI
Sbjct: 2069 QDMGPHL-RFYLDGGSLVLKGLRASDAG-AYTCVAHNPAGEDARLHTVNVLVPPTIKQGA 2126
Query: 290 ----TFLESPTSDHHWCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGC 345
T + P P V+G+P + W +G L S+ T +H + HT
Sbjct: 2127 DGSGTLVSRPGELVTMVCP--VRGSPPIHVSWLKDGLPLPLSQR--TLLHGSGHT----- 2177
Query: 346 LQLDNPTHMNNGDYTLIAKNEYGKDEKQIS 375
L++ + G +T +A + G ++ +
Sbjct: 2178 LRISKVQLADAGIFTCVAASPAGVADRNFT 2207
Score = 45.1 bits (105), Expect = 2e-04
Identities = 29/113 (25%), Positives = 46/113 (40%), Gaps = 2/113 (1%)
Query: 176 CLNESSKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYW-DVGN 234
CL E+ + + + P + ++TV G + L C G+P P + W G
Sbjct: 3097 CLAENEMGVAKKVVILVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQ 3156
Query: 235 LVSKHMNETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAP 287
+ + GSL + N+ + D+G CVA NL+G L V P
Sbjct: 3157 PLRASRRLRTLPDGSLWLENVETGDAG-TYDCVAHNLLGSATARAFLVVRGEP 3208
Score = 44.7 bits (104), Expect = 2e-04
Identities = 47/187 (25%), Positives = 71/187 (37%), Gaps = 19/187 (10%)
Query: 197 PSANLAAPNLTVEEGKSITLSCSVAGDPVPNM-YWDVGNLVSKHMNETSHT---QGSLRI 252
P+ + NLT+ L C +G P P + +W G + + + ++ +L +
Sbjct: 2573 PAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLL 2632
Query: 253 TNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESP---TSDHHWCIPFTVKG 309
T DS Q CV N VGE +TVH PTI ++ T + G
Sbjct: 2633 TAPGPQDSA-QFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTG 2691
Query: 310 NPKPALQWFYNGAILNE--SKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEY 367
P P + W GA L S Y G L++ ++ G YT A+N
Sbjct: 2692 IPAPTVSWSKAGAQLGARGSGY---------RVSPSGALEIGQALPIHAGRYTCSARNSA 2742
Query: 368 GKDEKQI 374
G K +
Sbjct: 2743 GVAHKHV 2749
Score = 44.7 bits (104), Expect = 2e-04
Identities = 42/169 (24%), Positives = 69/169 (40%), Gaps = 14/169 (8%)
Query: 205 NLTVEEGKSITLSCSVAGDPVPNMYWDVGN--LVSKHMNETSHTQGSLRITNISSDDSGK 262
+ TV + L+C G P P + W L ++ G+L I +G+
Sbjct: 2674 DFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGR 2733
Query: 263 QISCVAENLVGEDQDSVNLTVHFAPTITFLES---PTSDHHWCIPFTVKGNPKPALQWFY 319
+C A N G V LTV +P + L S ++ +P G P+P + W
Sbjct: 2734 Y-TCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQK 2792
Query: 320 NGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYG 368
G LN + + T++ G L++ + + + G+Y IAKN G
Sbjct: 2793 EG--LNVATGVSTQVLP------GGQLRIAHASPEDAGNYLCIAKNSAG 2833
Score = 44.3 bits (103), Expect = 3e-04
Identities = 46/192 (23%), Positives = 75/192 (39%), Gaps = 19/192 (9%)
Query: 206 LTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHMNETS-HTQG-SLRITNISSDDSGKQ 263
L G+ +T+ C V G P ++ W L T H G +LRI+ + D+G
Sbjct: 2132 LVSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGI- 2190
Query: 264 ISCVAENLVGEDQDSVNLTVHFAPTITFLESPTS-----DHHWCIPFTVKGNPKPALQWF 318
+CVA + G + L V P + +E +P +G P P + W
Sbjct: 2191 FTCVAASPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWM 2250
Query: 319 YNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQISAHF 378
+G L ++ E LQL+ ++G Y+ +A +E G+ +
Sbjct: 2251 KDGEPL-----------LSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTV 2299
Query: 379 MGWPGIDDGANP 390
M P I+D P
Sbjct: 2300 MEPPHIEDSGQP 2311
Score = 43.9 bits (102), Expect = 4e-04
Identities = 41/194 (21%), Positives = 70/194 (36%), Gaps = 16/194 (8%)
Query: 206 LTVEEGKSITLSCSVAGDPVPNMYW-DVGNLVSKHMNETSHTQGSLRITNISSDDSGKQ- 263
LTV EG +LSC G P P + W G + H R+ + ++
Sbjct: 981 LTVREGHPTSLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEG 1040
Query: 264 -ISCVAENLVGEDQDSVNLTVHFAPTITFLESP------TSDHHWCIPFTVKGNPKPALQ 316
+C N+VG + L VH P I P D + G P P +
Sbjct: 1041 TYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPTVT 1100
Query: 317 WFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQISA 376
W +G + + + N + L ++ + G Y+ +A+N G+ E++
Sbjct: 1101 WERDGQPVGAE----LGLQLQNQGQ---SLHVERAQAAHTGRYSCVAENLAGRAERKFEL 1153
Query: 377 HFMGWPGIDDGANP 390
+ P + +P
Sbjct: 1154 SVLVPPELIGDLDP 1167
Score = 42.4 bits (98), Expect = 0.001
Identities = 56/226 (24%), Positives = 77/226 (34%), Gaps = 25/226 (11%)
Query: 161 TLQEAKSSPDTQDLY---CLNESSKNIPLANLQIPNCGLPSANLAAPN-----LTVEEGK 212
TLQ ++ +Y LN + ++ L L + +P A AP + V G
Sbjct: 1801 TLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVL---VPPAFRQAPRGPQDAVLVRVGD 1857
Query: 213 SITLSCSVAGDPVPNMYW--DVGNLVSKHMNETSHTQGSLRITNISSDDSGKQISCVAEN 270
LSC P P + W D LV + L I D G SC N
Sbjct: 1858 KAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLY-SCKVSN 1916
Query: 271 LVGEDQDSVNLTVHFAPTI----TFLESPTSDHHWCIPFTVKGNPKPALQWFYNGAILNE 326
+ GE + LTV PT T S + + V G P P + W + +
Sbjct: 1917 VAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVES 1976
Query: 327 SKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEK 372
S V G LQL G YT +A+N + K
Sbjct: 1977 SA-------VHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAEARK 2015
Score = 42.4 bits (98), Expect = 0.001
Identities = 47/195 (24%), Positives = 77/195 (39%), Gaps = 26/195 (13%)
Query: 205 NLTVEEGKSITLSCSVAGDPVPNMYW--DVGNLVSKHMNETSHTQGSLRITNISSDDSGK 262
++ V G + L C G P+P + W D L+S+ + + SL++ + + DSG
Sbjct: 2224 DVVVVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQSLEQGP----SLQLEAVGAGDSG- 2278
Query: 263 QISCVAENLVGEDQDSVNLTVHFAPTITFLESPTS-----DHHWCIPFTVKGNPKPALQW 317
SCVA + GE + LTV P I PT + +G P+P + W
Sbjct: 2279 TYSCVAVSEAGEARRHFQLTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITW 2338
Query: 318 FYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQISAH 377
+G L + N++ L++ + G YT +A++ G EK
Sbjct: 2339 HKDGQALT---------RLENNSRATRVLRV-----RDAGLYTCLAESPAGAIEKSFRVR 2384
Query: 378 FMGWPGIDDGANPNY 392
P I P +
Sbjct: 2385 VQAPPNIVGPRGPRF 2399
Score = 42.0 bits (97), Expect = 0.001
Identities = 44/174 (25%), Positives = 69/174 (39%), Gaps = 17/174 (9%)
Query: 208 VEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHMNETSHTQGS--LRITNISSDDSGKQIS 265
+ E L C P P++ W + +E S QG L+I + ++++G+ S
Sbjct: 1571 IVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRY-S 1629
Query: 266 CVAENLVGEDQDSVNLTVHFAPTI-----TFLESPTSDHHWCIPF--TVKGNPKPALQWF 318
C A N VGED L V P I +E T + + GNP P + W
Sbjct: 1630 CKASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPVPTISWL 1689
Query: 319 YNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEK 372
NG + S ++ V + LQ+ + Y +A+N+ G EK
Sbjct: 1690 QNGLPFSPS----PRLQVLEDGQ---VLQVSTAEVADAASYMCVAENQAGSAEK 1736
Score = 40.0 bits (92), Expect = 0.006
Identities = 42/176 (23%), Positives = 61/176 (34%), Gaps = 12/176 (6%)
Query: 205 NLTVEEGKSITLSCSVAGDPVPNMYW--DVGNLVSKHMNETSHTQGSLRITNISSDDSGK 262
N++V +S+ L C P P + W D L + S + L++ D+G
Sbjct: 888 NVSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVWDAG- 946
Query: 263 QISCVAENLVGEDQDSVNLTVHFAPTITFLESPT----SDHHWCIPFTVKGNPKPALQWF 318
+C A N G + NL V AP ES T H + +G P P + W
Sbjct: 947 HYTCEALNQAGRSEKHYNLNVWVAPVFPLRESHTLTVREGHPTSLSCECRGVPFPKISWR 1006
Query: 319 YNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQI 374
+G L + Y G QL G YT N G + +
Sbjct: 1007 KDGQPLPGEGAGLQHVSAVGRLLYLGQAQL-----AQEGTYTCECSNVVGNSSQDL 1057
Score = 34.7 bits (78), Expect = 0.23
Identities = 30/115 (26%), Positives = 47/115 (40%), Gaps = 5/115 (4%)
Query: 177 LNESSKNIPLANLQIPNCGL--PSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYW-DVG 233
L E+ KN + L P+ P + + + ++TL C P P + W G
Sbjct: 1427 LGEAVKNYHVEVLIPPSISKDDPLGEVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDG 1486
Query: 234 NLVSKHMNETSHTQGSL-RITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAP 287
V+ +G L +I DSG+ + CVA N+ GED N+ + P
Sbjct: 1487 QPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYL-CVATNVAGEDDQDFNVLIQVPP 1540
Score = 32.3 bits (72), Expect = 1.2
Identities = 32/134 (23%), Positives = 49/134 (36%), Gaps = 14/134 (10%)
Query: 199 ANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHMNETSHTQG--SLRITNIS 256
A L +T S++L C V P P + W + E G +L++
Sbjct: 1749 AGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRAR 1808
Query: 257 SDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDH---------HWCIPFTV 307
DSG +C A N G DQ V L+V P F ++P +
Sbjct: 1809 LSDSG-MYTCEALNAAGRDQKLVQLSVLVPP--AFRQAPRGPQDAVLVRVGDKAVLSCET 1865
Query: 308 KGNPKPALQWFYNG 321
P+P + W+ +G
Sbjct: 1866 DALPEPTVTWYKDG 1879
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 67.0 bits (162), Expect = 4e-11
Identities = 58/223 (26%), Positives = 91/223 (40%), Gaps = 18/223 (8%)
Query: 162 LQEAKSSPDTQDLY-CLNESSKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSV 220
L+ A +SP+ Y C+ ++S + ++ P P+L+ EG L C
Sbjct: 2720 LRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKA 2779
Query: 221 AGDPVPNMYWDV-GNLVSKHMNE-TSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDS 278
G P PN+ WD G VS + T G L + N+ D+G +C AEN VG +
Sbjct: 2780 RGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAG-TYTCTAENAVGRARRR 2838
Query: 279 VNLTVHFAPTITFLESPTS----DHHWCIPFTVKGNPKPALQWFYNGAILNESKYICTKI 334
V+LT+ P T L S D W + +G+P P + W N + E
Sbjct: 2839 VHLTILVLPVFTTLPGDRSLRLGDRLW-LRCAARGSPTPRIGWTVNDRPVTEG------- 2890
Query: 335 HVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQISAH 377
+ + LQ + ++G Y A+N G+ + H
Sbjct: 2891 --VSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVH 2931
Score = 58.2 bits (139), Expect = 2e-08
Identities = 50/164 (30%), Positives = 69/164 (42%), Gaps = 17/164 (10%)
Query: 211 GKSITLSCSVAGDPVPNMYWDVGNLVSKHMNETSHTQ-GSLRITNISSDDSGKQISCVAE 269
G SI L C V GDPVP+++W L + + Q GSL I DD+G+ C+AE
Sbjct: 2951 GGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIRRTERDDAGR-YQCLAE 3009
Query: 270 NLVGEDQDSVNLTVHFAPTITFLESP-----TSDHHWCIPFTVKGNPKPALQWFYNGAIL 324
N +G + V L + AP F P S + G P P ++W G L
Sbjct: 3010 NEMGVAKKVVILVLQSAP--VFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPL 3067
Query: 325 NESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYG 368
S+ + T G L L+N + G Y +A N G
Sbjct: 3068 RASRRL--------RTLPDGSLWLENVETGDAGTYDCVAHNLLG 3103
Score = 56.2 bits (134), Expect = 8e-08
Identities = 44/179 (24%), Positives = 76/179 (42%), Gaps = 18/179 (10%)
Query: 206 LTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHMNETSHTQG--SLRITNISSDDSGKQ 263
+ V E + L C G P PN+ W + + +T+G L++ S D+G
Sbjct: 230 VAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAG-V 288
Query: 264 ISCVAENLVGEDQDSVNLTVHFAPTI------TFLESPTSDHHWCIPFTVKGNPKPALQW 317
+C A N VG + + L V+ PTI ++ + + +G+P P L W
Sbjct: 289 YTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGHPSPTLSW 348
Query: 318 FYNGAILNESKYICTKIHVTNHTEYHG-CLQLDNPTHMNNGDYTLIAKNEYGKDEKQIS 375
+ G + ES + E G L+L++P ++G Y+ +A + G+ Q S
Sbjct: 349 HHEGLPVAESN--------ESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYS 399
Score = 54.3 bits (129), Expect = 3e-07
Identities = 49/166 (29%), Positives = 71/166 (42%), Gaps = 15/166 (9%)
Query: 214 ITLSCSVAGDPVPNMYW-DVGNLVSKHMNETSHTQGSLRITNISS---DDSGKQISCVAE 269
+ L+C+ G P P + W GN VS R+ ++S DSG+ SCVA
Sbjct: 713 VRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRY-SCVAV 771
Query: 270 NLVGEDQDSVNLTVHFAPTITFLE---SPTSDHHWCIPFTVKGNPKPALQWFYNGAILNE 326
+ VGED+ V L VH P+I E S ++ + P P L W+ +G L
Sbjct: 772 SAVGEDRQDVVLQVHMPPSILGEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPLEP 831
Query: 327 SKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEK 372
+H++ LQ+D + G YT A N+ G EK
Sbjct: 832 R----PGVHLSAD---KALLQVDRADVWDAGHYTCEALNQAGHSEK 870
Score = 52.8 bits (125), Expect = 8e-07
Identities = 52/224 (23%), Positives = 93/224 (41%), Gaps = 19/224 (8%)
Query: 164 EAKSSPDTQDLYCLNESSKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGD 223
+A S+ D+ D C ++ ++ +P+ P + V ++ L C G
Sbjct: 2358 QALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGV 2417
Query: 224 PVPNMYW--DVGNLVSKHMNETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNL 281
P P + W D L + +GSLRI + + D+G + C+A N G D+ +L
Sbjct: 2418 PAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYL-CLASNSAGSDRQGRDL 2476
Query: 282 TVHFAPTITFLESP-----TSDHHWCIPFTVKGNPKPALQWFYNGAILN-ESKYICTKIH 335
V P I SP T+ +P G+PKP + W+ +G L+ + ++
Sbjct: 2477 RVLEPPAIA--PSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLL 2534
Query: 336 VTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEK--QISAH 377
+N L L P ++ + + NE G+ + Q++ H
Sbjct: 2535 PSN------ALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVH 2572
Score = 52.4 bits (124), Expect = 1e-06
Identities = 52/191 (27%), Positives = 77/191 (40%), Gaps = 22/191 (11%)
Query: 206 LTVEEGKSITLSCSVAGDPVPNMYW--DVGNLVSKHMNETSHTQGSLRITNISSDDSGKQ 263
+ V +G++ L C+V G P P + W D L + S L++ + +G
Sbjct: 1173 IKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAG-H 1231
Query: 264 ISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHHWCIPFTVKGN----------PKP 313
SC+A N VGE L+V APTI ++D + TV P P
Sbjct: 1232 YSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEE--VTVTVNNPISLICEALAFPSP 1289
Query: 314 ALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQ 373
+ W +GA S+ I + T HG LQ+ N + G YT + NE G+ K
Sbjct: 1290 NITWMKDGAPFEASR----NIQLLPGT--HG-LQILNAQKEDAGQYTCVVTNELGEAVKN 1342
Query: 374 ISAHFMGWPGI 384
+ P I
Sbjct: 1343 YHVEVLIPPSI 1353
Score = 52.0 bits (123), Expect = 1e-06
Identities = 54/202 (26%), Positives = 80/202 (39%), Gaps = 17/202 (8%)
Query: 179 ESSKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNL-VS 237
ES + + L L PN N A V E S+TL C +G P P++ W G+ VS
Sbjct: 591 ESKREVALKVLVPPNIEPGPVNKA-----VLENASVTLECLASGVPPPDVSWFKGHQPVS 645
Query: 238 KHMNETSHTQGS-LRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPT 296
M T G LRI D+G CVA N+ G + L V+ P IT S
Sbjct: 646 SWMGVTVSVDGRVLRIEQAQLSDAG-SYRCVASNVAGSTELRYGLRVNVPPRITLPPSLP 704
Query: 297 SDHHWCIPF----TVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPT 352
P G P P L W +G ++ + ++ L L +
Sbjct: 705 GPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRV-----LTLASAR 759
Query: 353 HMNNGDYTLIAKNEYGKDEKQI 374
++G Y+ +A + G+D + +
Sbjct: 760 ASDSGRYSCVAVSAVGEDRQDV 781
Score = 51.6 bits (122), Expect = 2e-06
Identities = 51/171 (29%), Positives = 66/171 (38%), Gaps = 18/171 (10%)
Query: 211 GKSITLSCSVAGDPVPNMYWDVGNLV----SKHMNETSHTQGSLRITNISSDDSGKQISC 266
G + L C +G P P + W H+ Q LRIT D G+ C
Sbjct: 141 GADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQ-VLRITGSHVGDEGR-YQC 198
Query: 267 VAENLVGEDQDSVNLTVHFAPTI-----TFLESPTSDHHWCIPFTVKGNPKPALQWFYNG 321
VA + G+ L VH PTI T + DH + +G P P + WF +G
Sbjct: 199 VAFSPAGQQARDFQLRVHAPPTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWFKDG 258
Query: 322 AILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEK 372
A+L S TK+ T LQL + G YT A N G EK
Sbjct: 259 ALLPTS----TKVVYTRGGRQ---LQLGRAQSSDAGVYTCKASNAVGAAEK 302
Score = 51.6 bits (122), Expect = 2e-06
Identities = 53/202 (26%), Positives = 85/202 (42%), Gaps = 29/202 (14%)
Query: 206 LTVEEGKSITLSCSVAGDPVPNMYW-DVGNLVSKHMNETSHTQG-SLRITNISSDDSGKQ 263
+T G+ + L C +G PVP + W G + +QG +L I ++ D SG
Sbjct: 417 VTTIVGQPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGTTLHIDHVELDHSG-L 475
Query: 264 ISCVAENLVGEDQDSVNLTVH--FAPTITFLESPTSDHHW-----------CIPFTVKG- 309
+C A N G V ++VH +AP + LE P +HW C P +G
Sbjct: 476 FACQATNEAGTAGAEVEVSVHGEWAPGV--LEVPIGQYHWGXEHHSSFPAACDPPVHRGW 533
Query: 310 --NPKPAL--QWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKN 365
+PKP L W G++ E I + LQ++ + G YT A N
Sbjct: 534 GAHPKPPLVEGWCSPGSLWGEPTGIPVAYSLPPP------LQIEKVDLRDEGIYTCAATN 587
Query: 366 EYGKDEKQISAHFMGWPGIDDG 387
G+ +++++ + P I+ G
Sbjct: 588 LAGESKREVALKVLVPPNIEPG 609
Score = 50.8 bits (120), Expect = 3e-06
Identities = 44/187 (23%), Positives = 69/187 (36%), Gaps = 18/187 (9%)
Query: 206 LTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHMNETSHTQGSLRITNISSDDSGKQIS 265
L++ G + L C G P PN+ W + S LR+ D+G +
Sbjct: 2223 LSLTPGAPMELLCDAQGTPQPNITWHKDGQALTRLENNSRATRVLRVR-----DAG-LYT 2276
Query: 266 CVAENLVGEDQDSVNLTVHFAPTITFLESP-----TSDHHWCIPFTVKGNPKPALQWFYN 320
C+AE+ G + S + V P I P + + +V+ P P + W +
Sbjct: 2277 CLAESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAPKITWHRD 2336
Query: 321 GAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQISAHFMG 380
G +L E + T E LQL + ++GDY+ A+N G
Sbjct: 2337 GIVLQEDAH-------TQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHT 2389
Query: 381 WPGIDDG 387
P I G
Sbjct: 2390 VPTIRSG 2396
Score = 50.8 bits (120), Expect = 3e-06
Identities = 43/169 (25%), Positives = 68/169 (40%), Gaps = 15/169 (8%)
Query: 211 GKSITLSCSVAGDPVPNMYWDVGNLVSKHMNETSHTQGSLRITNISSDDSGKQISCVAEN 270
G + L C+ G P P + W V + +L+ +S +DSG + C AEN
Sbjct: 2861 GDRLWLRCAARGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYV-CWAEN 2919
Query: 271 LVGEDQDSVNLTVHFAPTI-----TFLESPTSDHHWCIPFTVKGNPKPALQWFYNGAILN 325
VG Q + V AP + ++L P + V+G+P P + W +G L
Sbjct: 2920 RVGRTQAVSFVHVKEAPVLQGEAFSYLVEPVGGSIQ-LDCVVRGDPVPDIHWIKDGLPLR 2978
Query: 326 ESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQI 374
S H +G L + + G Y +A+NE G +K +
Sbjct: 2979 GSHL--------RHQLQNGSLTIRRTERDDAGRYQCLAENEMGVAKKVV 3019
Score = 50.4 bits (119), Expect = 4e-06
Identities = 48/189 (25%), Positives = 83/189 (43%), Gaps = 21/189 (11%)
Query: 208 VEEGKSITLSCSVAGDPVPNMYWDV-GNLVSKHMNETSHTQG-SLRITNISSDDSGKQIS 265
V++G + TL C+ G P P + W+ G V + QG SL + + +G+ S
Sbjct: 989 VQDGVA-TLECNATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRY-S 1046
Query: 266 CVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHHWCI--PFTV----KGNPKPALQWFY 319
CVAENL G + L+V P + P ++ + P T+ G P PA++WF
Sbjct: 1047 CVAENLAGRAERKFELSVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFR 1106
Query: 320 NGAILN--ESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQISAH 377
++ E Y+ + L++ ++G Y+ +A NE G+ + S
Sbjct: 1107 GEEPVSPGEDTYLLAGGWM---------LKMTQTQEQDSGLYSCLASNEAGEARRNFSVE 1157
Query: 378 FMGWPGIDD 386
+ P I++
Sbjct: 1158 VLVPPSIEN 1166
Score = 50.4 bits (119), Expect = 4e-06
Identities = 54/196 (27%), Positives = 77/196 (39%), Gaps = 25/196 (12%)
Query: 205 NLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHMNETSHTQGS--LRITNISSDDSGK 262
N+T +TL C G P P + W G +T G L++T DSG
Sbjct: 1079 NITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSG- 1137
Query: 263 QISCVAENLVGEDQDSVNLTVHFAPT---------ITFLESPTSDHHWCIPFTVKGNPKP 313
SC+A N GE + + ++ V P+ I L+ T+ H C V G+P+P
Sbjct: 1138 LYSCLASNEAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTA-HLMC---NVTGHPQP 1193
Query: 314 ALQWFYNGAILNESKYICTKIHVTNHTEYHG-CLQLDNPTHMNNGDYTLIAKNEYGKDEK 372
L WF +G L +H G LQ+ + G Y+ IA N G+ K
Sbjct: 1194 KLTWFKDGRPLARGD--------AHHISPDGVLLQVLQANLSSAGHYSCIAANAVGEKTK 1245
Query: 373 QISAHFMGWPGIDDGA 388
+ P I GA
Sbjct: 1246 HFQLSVLLAPTILGGA 1261
Score = 50.1 bits (118), Expect = 5e-06
Identities = 45/187 (24%), Positives = 77/187 (41%), Gaps = 15/187 (8%)
Query: 211 GKSITLSCSVAGDPVPNMYW--DVGNLVSKHMNETSHTQGSLRITNISSDDSGKQISCVA 268
G + L+C V+G P P + W D + S ++ G L+++ + +G +CVA
Sbjct: 1857 GSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAG-TYTCVA 1915
Query: 269 ENLVGEDQDSVNLTVHFAPTITFLESPTSDHHWC------IPFTVKGNPKPALQWFYNGA 322
EN E + + V AP I +HH + G P P + W +G+
Sbjct: 1916 ENTQAEARKDFVVAVLVAPRIR-SSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGS 1974
Query: 323 ILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQISAHFMGWP 382
L + + ++ G L L + G YT +A N G+D + + + + P
Sbjct: 1975 PLGQDMGPHLRFYLDG-----GSLVLKGLRASDAGAYTCVAHNPAGEDARLHTVNVLVPP 2029
Query: 383 GIDDGAN 389
I GA+
Sbjct: 2030 TIKQGAD 2036
Score = 49.7 bits (117), Expect = 7e-06
Identities = 44/178 (24%), Positives = 73/178 (41%), Gaps = 20/178 (11%)
Query: 206 LTVEEGKSITLSCSVAGDPVPNMYWDVGNL---VSKHMNETSHTQGSLRITNISSDDSGK 262
+TV +++L C G+PVP + W L S + Q L+++ D+
Sbjct: 1573 VTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQ-VLQVSTAEVADAAS 1631
Query: 263 QISCVAENLVGEDQDSVNLTVHFAPTITFLE----SPTSDHHWCIPFTVKGNPKPALQWF 318
+ CVAEN G + L V P I L+ + + +P V +P P + W+
Sbjct: 1632 YM-CVAENQAGSAEKLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWY 1690
Query: 319 YNGAILN--ESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQI 374
+ L+ E ++ H LQL ++G YT A N G+D+K +
Sbjct: 1691 KDSQALSLGEEVFLLPGTHT---------LQLGRARLSDSGMYTCEALNAAGRDQKLV 1739
Score = 48.9 bits (115), Expect = 1e-05
Identities = 45/182 (24%), Positives = 68/182 (37%), Gaps = 15/182 (8%)
Query: 211 GKSITLSCSVAGDPVPNMYWDVGNLVSKHMNETS-HTQGSLRITNISSDDSGKQISCVAE 269
G+ + L C G P P + W L NE+ T GS+ + S SCVA
Sbjct: 329 GRPVALECVARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVAS 388
Query: 270 NLVGEDQDSVNLTVHFAPTITFLE-----SPTSDHHWCIPFTVKGNPKPALQWFYNGAIL 324
+ GE ++ V P + E + +P G+P P +QW NG
Sbjct: 389 SPAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNGRPA 448
Query: 325 NESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGK--DEKQISAHFMGWP 382
E + T L +D+ ++G + A NE G E ++S H P
Sbjct: 449 EELAGVQVASQGTT-------LHIDHVELDHSGLFACQATNEAGTAGAEVEVSVHGEWAP 501
Query: 383 GI 384
G+
Sbjct: 502 GV 503
Score = 46.2 bits (108), Expect = 8e-05
Identities = 56/253 (22%), Positives = 101/253 (39%), Gaps = 41/253 (16%)
Query: 147 GNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLN---ESSKNIPLANLQIPNCGLPSANLAA 203
G+ S D + ++ LQ SS N E +K+ L+ L P + + A
Sbjct: 1207 GDAHHISPDGVLLQVLQANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSAD 1266
Query: 204 PNLTVEEGKSITLSCSVAGDPVPNMYWDVGNL---VSKHMNETSHTQGSLRITNISSDDS 260
+TV I+L C P PN+ W S+++ T G L+I N +D+
Sbjct: 1267 EEVTVTVNNPISLICEALAFPSPNITWMKDGAPFEASRNIQLLPGTHG-LQILNAQKEDA 1325
Query: 261 GKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSD------------------HHWC 302
G Q +CV N +GE + ++ V P+I+ + P ++ W
Sbjct: 1326 G-QYTCVVTNELGEAVKNYHVEVLIPPSIS-KDDPLAEVGVKEVKTKVNSTLTLECESWA 1383
Query: 303 IPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLI 362
+ P P ++W+ +G + S +++ V LQ+ ++G Y +
Sbjct: 1384 V-------PPPTIRWYKDGQPVTPS----SRLQVLGEGR---LLQIQPTQVSDSGRYLCV 1429
Query: 363 AKNEYGKDEKQIS 375
A N G+D++ +
Sbjct: 1430 ATNVAGEDDQDFN 1442
Score = 45.4 bits (106), Expect = 1e-04
Identities = 53/210 (25%), Positives = 90/210 (42%), Gaps = 27/210 (12%)
Query: 179 ESSKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYW-----DVG 233
E+ K+ +A L P + S+ +A + V EG+ + L C G P P++ W +G
Sbjct: 1921 EARKDFVVAVLVAPR--IRSSGVAREH-HVLEGQEVRLDCEADGQPPPDVAWLKDGSPLG 1977
Query: 234 NLVSKHMNETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTI---- 289
+ H+ GSL + + + D+G +CVA N GED + V PTI
Sbjct: 1978 QDMGPHL-RFYLDGGSLVLKGLRASDAG-AYTCVAHNPAGEDARLHTVNVLVPPTIKQGA 2035
Query: 290 ----TFLESPTSDHHWCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGC 345
T + P P V+G+P + W +G L S+ T +H + HT
Sbjct: 2036 DGSGTLVSRPGELVTMVCP--VRGSPPIHVSWLKDGLPLPLSQR--TLLHGSGHT----- 2086
Query: 346 LQLDNPTHMNNGDYTLIAKNEYGKDEKQIS 375
L++ + G +T +A + G ++ +
Sbjct: 2087 LRISKVQLADAGIFTCVAASPAGVADRNFT 2116
Score = 45.1 bits (105), Expect = 2e-04
Identities = 29/113 (25%), Positives = 46/113 (40%), Gaps = 2/113 (1%)
Query: 176 CLNESSKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYW-DVGN 234
CL E+ + + + P + ++TV G + L C G+P P + W G
Sbjct: 3006 CLAENEMGVAKKVVILVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQ 3065
Query: 235 LVSKHMNETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAP 287
+ + GSL + N+ + D+G CVA NL+G L V P
Sbjct: 3066 PLRASRRLRTLPDGSLWLENVETGDAG-TYDCVAHNLLGSATARAFLVVRGEP 3117
Score = 44.7 bits (104), Expect = 2e-04
Identities = 47/187 (25%), Positives = 71/187 (37%), Gaps = 19/187 (10%)
Query: 197 PSANLAAPNLTVEEGKSITLSCSVAGDPVPNM-YWDVGNLVSKHMNETSHT---QGSLRI 252
P+ + NLT+ L C +G P P + +W G + + + ++ +L +
Sbjct: 2482 PAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLL 2541
Query: 253 TNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESP---TSDHHWCIPFTVKG 309
T DS Q CV N VGE +TVH PTI ++ T + G
Sbjct: 2542 TAPGPQDSA-QFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTG 2600
Query: 310 NPKPALQWFYNGAILNE--SKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEY 367
P P + W GA L S Y G L++ ++ G YT A+N
Sbjct: 2601 IPAPTVSWSKAGAQLGARGSGY---------RVSPSGALEIGQALPIHAGRYTCSARNSA 2651
Query: 368 GKDEKQI 374
G K +
Sbjct: 2652 GVAHKHV 2658
Score = 44.7 bits (104), Expect = 2e-04
Identities = 42/169 (24%), Positives = 69/169 (40%), Gaps = 14/169 (8%)
Query: 205 NLTVEEGKSITLSCSVAGDPVPNMYWDVGN--LVSKHMNETSHTQGSLRITNISSDDSGK 262
+ TV + L+C G P P + W L ++ G+L I +G+
Sbjct: 2583 DFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGR 2642
Query: 263 QISCVAENLVGEDQDSVNLTVHFAPTITFLES---PTSDHHWCIPFTVKGNPKPALQWFY 319
+C A N G V LTV +P + L S ++ +P G P+P + W
Sbjct: 2643 Y-TCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQK 2701
Query: 320 NGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYG 368
G LN + + T++ G L++ + + + G+Y IAKN G
Sbjct: 2702 EG--LNVATGVSTQVLP------GGQLRIAHASPEDAGNYLCIAKNSAG 2742
Score = 44.3 bits (103), Expect = 3e-04
Identities = 46/192 (23%), Positives = 75/192 (39%), Gaps = 19/192 (9%)
Query: 206 LTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHMNETS-HTQG-SLRITNISSDDSGKQ 263
L G+ +T+ C V G P ++ W L T H G +LRI+ + D+G
Sbjct: 2041 LVSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGI- 2099
Query: 264 ISCVAENLVGEDQDSVNLTVHFAPTITFLESPTS-----DHHWCIPFTVKGNPKPALQWF 318
+CVA + G + L V P + +E +P +G P P + W
Sbjct: 2100 FTCVAASPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWM 2159
Query: 319 YNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQISAHF 378
+G L ++ E LQL+ ++G Y+ +A +E G+ +
Sbjct: 2160 KDGEPL-----------LSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTV 2208
Query: 379 MGWPGIDDGANP 390
M P I+D P
Sbjct: 2209 MEPPHIEDSGQP 2220
Score = 43.1 bits (100), Expect = 7e-04
Identities = 41/194 (21%), Positives = 69/194 (35%), Gaps = 16/194 (8%)
Query: 206 LTVEEGKSITLSCSVAGDPVPNMYW-DVGNLVSKHMNETSHTQGSLRITNISSDDSGKQ- 263
LTV EG LSC G P P + W G + H R+ + ++
Sbjct: 890 LTVREGHPTRLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEG 949
Query: 264 -ISCVAENLVGEDQDSVNLTVHFAPTITFLESP------TSDHHWCIPFTVKGNPKPALQ 316
+C N+VG + L VH P I P D + G P P +
Sbjct: 950 TYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPTVT 1009
Query: 317 WFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQISA 376
W +G + + + N + L ++ + G Y+ +A+N G+ E++
Sbjct: 1010 WERDGQPVGAE----LGLQLQNQGQ---SLHVERAQAAHTGRYSCVAENLAGRAERKFEL 1062
Query: 377 HFMGWPGIDDGANP 390
+ P + +P
Sbjct: 1063 SVLVPPELIGDLDP 1076
Score = 42.4 bits (98), Expect = 0.001
Identities = 56/226 (24%), Positives = 77/226 (34%), Gaps = 25/226 (11%)
Query: 161 TLQEAKSSPDTQDLY---CLNESSKNIPLANLQIPNCGLPSANLAAPN-----LTVEEGK 212
TLQ ++ +Y LN + ++ L L + +P A AP + V G
Sbjct: 1710 TLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVL---VPPAFRQAPRGPQDAVLVRVGD 1766
Query: 213 SITLSCSVAGDPVPNMYW--DVGNLVSKHMNETSHTQGSLRITNISSDDSGKQISCVAEN 270
LSC P P + W D LV + L I D G SC N
Sbjct: 1767 KAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLY-SCKVSN 1825
Query: 271 LVGEDQDSVNLTVHFAPTI----TFLESPTSDHHWCIPFTVKGNPKPALQWFYNGAILNE 326
+ GE + LTV PT T S + + V G P P + W + +
Sbjct: 1826 VAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVES 1885
Query: 327 SKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEK 372
S V G LQL G YT +A+N + K
Sbjct: 1886 SA-------VHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAEARK 1924
Score = 42.4 bits (98), Expect = 0.001
Identities = 47/195 (24%), Positives = 77/195 (39%), Gaps = 26/195 (13%)
Query: 205 NLTVEEGKSITLSCSVAGDPVPNMYW--DVGNLVSKHMNETSHTQGSLRITNISSDDSGK 262
++ V G + L C G P+P + W D L+S+ + + SL++ + + DSG
Sbjct: 2133 DVVVVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQSLEQGP----SLQLEAVGAGDSG- 2187
Query: 263 QISCVAENLVGEDQDSVNLTVHFAPTITFLESPTS-----DHHWCIPFTVKGNPKPALQW 317
SCVA + GE + LTV P I PT + +G P+P + W
Sbjct: 2188 TYSCVAVSEAGEARRHFQLTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITW 2247
Query: 318 FYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQISAH 377
+G L + N++ L++ + G YT +A++ G EK
Sbjct: 2248 HKDGQALT---------RLENNSRATRVLRV-----RDAGLYTCLAESPAGAIEKSFRVR 2293
Query: 378 FMGWPGIDDGANPNY 392
P I P +
Sbjct: 2294 VQAPPNIVGPRGPRF 2308
Score = 42.0 bits (97), Expect = 0.001
Identities = 44/174 (25%), Positives = 69/174 (39%), Gaps = 17/174 (9%)
Query: 208 VEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHMNETSHTQGS--LRITNISSDDSGKQIS 265
+ E L C P P++ W + +E S QG L+I + ++++G+ S
Sbjct: 1480 IVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRY-S 1538
Query: 266 CVAENLVGEDQDSVNLTVHFAPTI-----TFLESPTSDHHWCIPF--TVKGNPKPALQWF 318
C A N VGED L V P I +E T + + GNP P + W
Sbjct: 1539 CKASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPVPTISWL 1598
Query: 319 YNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEK 372
NG + S ++ V + LQ+ + Y +A+N+ G EK
Sbjct: 1599 QNGLPFSPS----PRLQVLEDGQ---VLQVSTAEVADAASYMCVAENQAGSAEK 1645
Score = 39.3 bits (90), Expect = 0.010
Identities = 42/176 (23%), Positives = 61/176 (34%), Gaps = 12/176 (6%)
Query: 205 NLTVEEGKSITLSCSVAGDPVPNMYW--DVGNLVSKHMNETSHTQGSLRITNISSDDSGK 262
N++V +S+ L C P P + W D L + S + L++ D+G
Sbjct: 797 NVSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVWDAG- 855
Query: 263 QISCVAENLVGEDQDSVNLTVHFAPTITFLESPT----SDHHWCIPFTVKGNPKPALQWF 318
+C A N G + NL V AP ES T H + +G P P + W
Sbjct: 856 HYTCEALNQAGHSEKHYNLNVWVAPVFPLRESHTLTVREGHPTRLSCECRGVPFPKISWR 915
Query: 319 YNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQI 374
+G L + Y G QL G YT N G + +
Sbjct: 916 KDGQPLPGEGAGLQHVSAVGRLLYLGQAQL-----AQEGTYTCECSNVVGNSSQDL 966
Score = 36.2 bits (82), Expect = 0.081
Identities = 31/115 (26%), Positives = 48/115 (41%), Gaps = 5/115 (4%)
Query: 177 LNESSKNIPLANLQIPNCGL--PSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYW-DVG 233
L E+ KN + L P+ P A + + + ++TL C P P + W G
Sbjct: 1336 LGEAVKNYHVEVLIPPSISKDDPLAEVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDG 1395
Query: 234 NLVSKHMNETSHTQGSL-RITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAP 287
V+ +G L +I DSG+ + CVA N+ GED N+ + P
Sbjct: 1396 QPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYL-CVATNVAGEDDQDFNVLIQVPP 1449
Score = 32.7 bits (73), Expect = 0.89
Identities = 31/104 (29%), Positives = 40/104 (38%), Gaps = 22/104 (21%)
Query: 205 NLTVEEGKSITLSCSVAGDPVPNMYW------------------DVG-NLVSKHMNETSH 245
N++ G+S+TL C G PVP + W D+G V H
Sbjct: 27 NVSGMAGQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGH--RLLD 84
Query: 246 TQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTI 289
SL I DSG SC AEN G Q +L V P++
Sbjct: 85 EGQSLHFPRIQEGDSGLY-SCRAENQAGTAQRDFHLLVLTPPSV 127
Score = 32.3 bits (72), Expect = 1.2
Identities = 32/134 (23%), Positives = 49/134 (36%), Gaps = 14/134 (10%)
Query: 199 ANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHMNETSHTQG--SLRITNIS 256
A L +T S++L C V P P + W + E G +L++
Sbjct: 1658 AGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRAR 1717
Query: 257 SDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDH---------HWCIPFTV 307
DSG +C A N G DQ V L+V P F ++P +
Sbjct: 1718 LSDSG-MYTCEALNAAGRDQKLVQLSVLVPP--AFRQAPRGPQDAVLVRVGDKAVLSCET 1774
Query: 308 KGNPKPALQWFYNG 321
P+P + W+ +G
Sbjct: 1775 DALPEPTVTWYKDG 1788
>gi|153791507 leucine rich repeat neuronal 3 [Homo sapiens]
Length = 708
Score = 66.2 bits (160), Expect = 7e-11
Identities = 53/230 (23%), Positives = 101/230 (43%), Gaps = 14/230 (6%)
Query: 67 NITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSG-LKFVAHKAFLKNSNLQHINFTRN 125
++ E+ I N L I+ V+ LR + ++ L ++ AF + L+ + N
Sbjct: 285 HLKELGINNMPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSN 344
Query: 126 KLTSLSRKHFRHL-DLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLN------ 178
L++L L +L E+ + NP C C I W+ + + L+C++
Sbjct: 345 ALSALYHGTIESLPNLKEISIHSNPIRCDCVIRWMNMNKTNIRFMEPDSLFCVDPPEFQG 404
Query: 179 ESSKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGN---L 235
++ + + ++ L + NL VE G ++ C +P P +YW + L
Sbjct: 405 QNVRQVHFRDMMEICLPLIAPESFPSNLNVEAGSYVSFHCRATAEPQPEIYWITPSGQKL 464
Query: 236 VSKHMNET--SHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTV 283
+ + + H++G+L I ++ + G +C+A NLVG D SV + V
Sbjct: 465 LPNTLTDKFYVHSEGTLDINGVTPKEGG-LYTCIATNLVGADLKSVMIKV 513
Score = 33.9 bits (76), Expect = 0.40
Identities = 74/326 (22%), Positives = 123/326 (37%), Gaps = 47/326 (14%)
Query: 67 NITEIFIANQKRLEIINEDDVEAYVGLRNLTIV---DSGLKFVAHKAFLKNSNLQHINFT 123
N+ + IA EI + A VGL NL + D+ L V H A K NL+ ++
Sbjct: 213 NLRSLVIAGINLTEIPDN----ALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLN 268
Query: 124 RNKLTSLSRKHFRH-LDLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLNESSK 182
+N + + R F + L L EL + P S D + + L PD + + E++
Sbjct: 269 KNPINRIRRGDFSNMLHLKELGINNMPELISIDSLAVDNL------PDLRKI----EATN 318
Query: 183 NIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAG--DPVPNMYWDVGNLVSKHM 240
N L+ + P+A P L S LS G + +PN+ +S H
Sbjct: 319 NPRLSYIH------PNAFFRLPKLESLMLNSNALSALYHGTIESLPNL-----KEISIHS 367
Query: 241 N----ETSHTQGSLRITNISSDDSGKQISCVAENLVGED------QDSVNLTVHFAPTIT 290
N + ++ TNI + G++ +D + + + +
Sbjct: 368 NPIRCDCVIRWMNMNKTNIRFMEPDSLFCVDPPEFQGQNVRQVHFRDMMEICLPLIAPES 427
Query: 291 FLESPTSDHHWCIPFTVK--GNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQL 348
F + + + F + P+P + W + K +V H+E G L +
Sbjct: 428 FPSNLNVEAGSYVSFHCRATAEPQPEIYWITPSGQKLLPNTLTDKFYV--HSE--GTLDI 483
Query: 349 DNPTHMNNGDYTLIAKNEYGKDEKQI 374
+ T G YT IA N G D K +
Sbjct: 484 NGVTPKEGGLYTCIATNLVGADLKSV 509
>gi|153792651 leucine rich repeat neuronal 3 [Homo sapiens]
Length = 708
Score = 66.2 bits (160), Expect = 7e-11
Identities = 53/230 (23%), Positives = 101/230 (43%), Gaps = 14/230 (6%)
Query: 67 NITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSG-LKFVAHKAFLKNSNLQHINFTRN 125
++ E+ I N L I+ V+ LR + ++ L ++ AF + L+ + N
Sbjct: 285 HLKELGINNMPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSN 344
Query: 126 KLTSLSRKHFRHL-DLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLN------ 178
L++L L +L E+ + NP C C I W+ + + L+C++
Sbjct: 345 ALSALYHGTIESLPNLKEISIHSNPIRCDCVIRWMNMNKTNIRFMEPDSLFCVDPPEFQG 404
Query: 179 ESSKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGN---L 235
++ + + ++ L + NL VE G ++ C +P P +YW + L
Sbjct: 405 QNVRQVHFRDMMEICLPLIAPESFPSNLNVEAGSYVSFHCRATAEPQPEIYWITPSGQKL 464
Query: 236 VSKHMNET--SHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTV 283
+ + + H++G+L I ++ + G +C+A NLVG D SV + V
Sbjct: 465 LPNTLTDKFYVHSEGTLDINGVTPKEGG-LYTCIATNLVGADLKSVMIKV 513
Score = 33.9 bits (76), Expect = 0.40
Identities = 74/326 (22%), Positives = 123/326 (37%), Gaps = 47/326 (14%)
Query: 67 NITEIFIANQKRLEIINEDDVEAYVGLRNLTIV---DSGLKFVAHKAFLKNSNLQHINFT 123
N+ + IA EI + A VGL NL + D+ L V H A K NL+ ++
Sbjct: 213 NLRSLVIAGINLTEIPDN----ALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLN 268
Query: 124 RNKLTSLSRKHFRH-LDLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLNESSK 182
+N + + R F + L L EL + P S D + + L PD + + E++
Sbjct: 269 KNPINRIRRGDFSNMLHLKELGINNMPELISIDSLAVDNL------PDLRKI----EATN 318
Query: 183 NIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAG--DPVPNMYWDVGNLVSKHM 240
N L+ + P+A P L S LS G + +PN+ +S H
Sbjct: 319 NPRLSYIH------PNAFFRLPKLESLMLNSNALSALYHGTIESLPNL-----KEISIHS 367
Query: 241 N----ETSHTQGSLRITNISSDDSGKQISCVAENLVGED------QDSVNLTVHFAPTIT 290
N + ++ TNI + G++ +D + + + +
Sbjct: 368 NPIRCDCVIRWMNMNKTNIRFMEPDSLFCVDPPEFQGQNVRQVHFRDMMEICLPLIAPES 427
Query: 291 FLESPTSDHHWCIPFTVK--GNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQL 348
F + + + F + P+P + W + K +V H+E G L +
Sbjct: 428 FPSNLNVEAGSYVSFHCRATAEPQPEIYWITPSGQKLLPNTLTDKFYV--HSE--GTLDI 483
Query: 349 DNPTHMNNGDYTLIAKNEYGKDEKQI 374
+ T G YT IA N G D K +
Sbjct: 484 NGVTPKEGGLYTCIATNLVGADLKSV 509
>gi|153792227 leucine rich repeat neuronal 3 [Homo sapiens]
Length = 708
Score = 66.2 bits (160), Expect = 7e-11
Identities = 53/230 (23%), Positives = 101/230 (43%), Gaps = 14/230 (6%)
Query: 67 NITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSG-LKFVAHKAFLKNSNLQHINFTRN 125
++ E+ I N L I+ V+ LR + ++ L ++ AF + L+ + N
Sbjct: 285 HLKELGINNMPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSN 344
Query: 126 KLTSLSRKHFRHL-DLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLN------ 178
L++L L +L E+ + NP C C I W+ + + L+C++
Sbjct: 345 ALSALYHGTIESLPNLKEISIHSNPIRCDCVIRWMNMNKTNIRFMEPDSLFCVDPPEFQG 404
Query: 179 ESSKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGN---L 235
++ + + ++ L + NL VE G ++ C +P P +YW + L
Sbjct: 405 QNVRQVHFRDMMEICLPLIAPESFPSNLNVEAGSYVSFHCRATAEPQPEIYWITPSGQKL 464
Query: 236 VSKHMNET--SHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTV 283
+ + + H++G+L I ++ + G +C+A NLVG D SV + V
Sbjct: 465 LPNTLTDKFYVHSEGTLDINGVTPKEGG-LYTCIATNLVGADLKSVMIKV 513
Score = 33.9 bits (76), Expect = 0.40
Identities = 74/326 (22%), Positives = 123/326 (37%), Gaps = 47/326 (14%)
Query: 67 NITEIFIANQKRLEIINEDDVEAYVGLRNLTIV---DSGLKFVAHKAFLKNSNLQHINFT 123
N+ + IA EI + A VGL NL + D+ L V H A K NL+ ++
Sbjct: 213 NLRSLVIAGINLTEIPDN----ALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLN 268
Query: 124 RNKLTSLSRKHFRH-LDLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLNESSK 182
+N + + R F + L L EL + P S D + + L PD + + E++
Sbjct: 269 KNPINRIRRGDFSNMLHLKELGINNMPELISIDSLAVDNL------PDLRKI----EATN 318
Query: 183 NIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAG--DPVPNMYWDVGNLVSKHM 240
N L+ + P+A P L S LS G + +PN+ +S H
Sbjct: 319 NPRLSYIH------PNAFFRLPKLESLMLNSNALSALYHGTIESLPNL-----KEISIHS 367
Query: 241 N----ETSHTQGSLRITNISSDDSGKQISCVAENLVGED------QDSVNLTVHFAPTIT 290
N + ++ TNI + G++ +D + + + +
Sbjct: 368 NPIRCDCVIRWMNMNKTNIRFMEPDSLFCVDPPEFQGQNVRQVHFRDMMEICLPLIAPES 427
Query: 291 FLESPTSDHHWCIPFTVK--GNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQL 348
F + + + F + P+P + W + K +V H+E G L +
Sbjct: 428 FPSNLNVEAGSYVSFHCRATAEPQPEIYWITPSGQKLLPNTLTDKFYV--HSE--GTLDI 483
Query: 349 DNPTHMNNGDYTLIAKNEYGKDEKQI 374
+ T G YT IA N G D K +
Sbjct: 484 NGVTPKEGGLYTCIATNLVGADLKSV 509
>gi|109150416 peroxidasin [Homo sapiens]
Length = 1479
Score = 64.3 bits (155), Expect = 3e-10
Identities = 54/221 (24%), Positives = 93/221 (42%), Gaps = 16/221 (7%)
Query: 196 LPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDV-GNLVSKHMNETSHTQGSLRITN 254
LP + + V EG+++ C G+P P + W G+ +S + G+LRI+
Sbjct: 432 LPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHLVLSSGTLRISG 491
Query: 255 ISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTS-----DHHWCIPFTVKG 309
++ D G Q C A N++G + +LTV T F P+ + +P + +G
Sbjct: 492 VALHDQG-QYECQAVNIIGSQKVVAHLTVQPRVTPVFASIPSDTTVEVGANVQLPCSSQG 550
Query: 310 NPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGK 369
P+PA+ W +G + ES K H++ G L +++ + G Y +A+N G
Sbjct: 551 EPEPAITWNKDGVQVTES----GKFHISP----EGFLTINDVGPADAGRYECVARNTIGS 602
Query: 370 DEKQISAHFMGWPGIDDGANPNYPDVIYEDYGTAANDIGDT 410
+ + P + +P I E T I T
Sbjct: 603 ASVSMVLS-VNVPDVSRNGDPFVATSIVEAIATVDRAINST 642
Score = 58.9 bits (141), Expect = 1e-08
Identities = 65/319 (20%), Positives = 123/319 (38%), Gaps = 27/319 (8%)
Query: 64 DPENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAFLKNSNLQHINFT 123
D EN+ +++ + ++ I+ + L L + + ++ + +F L+ +
Sbjct: 108 DLENLKYLYLYKNE-IQSIDRQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLH 166
Query: 124 RNKLTSLSRKHFRHLD-LSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLNE--- 179
N++T L F HL+ + L L N C C+I+W+ L + + + E
Sbjct: 167 NNRITHLVPGTFNHLESMKRLRLDSNTLHCDCEILWLADLLKTYAESGNAQAAAICEYPR 226
Query: 180 --SSKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVS 237
+++ + NC P + V G ++ +C G+P P + W + N
Sbjct: 227 RIQGRSVATITPEELNCERPRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIW-LRNNNE 285
Query: 238 KHMNETSH----TQGSLRITNISSDDSGKQISCVAENLVGE-DQDSVNLTVHFAPT-ITF 291
M S G+L I N D G C+A+N+ GE V L +P TF
Sbjct: 286 LSMKTDSRLNLLDDGTLMIQNTQETDQG-IYQCMAKNVAGEVKTQEVTLRYFGSPARPTF 344
Query: 292 LESPTS-----DHHWCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCL 346
+ P + + + G+P P + W + ++++T G L
Sbjct: 345 VIQPQNTEVLVGESVTLECSATGHPPPRISWTRGD---RTPLPVDPRVNITP----SGGL 397
Query: 347 QLDNPTHMNNGDYTLIAKN 365
+ N ++G+Y A N
Sbjct: 398 YIQNVVQGDSGEYACSATN 416
Score = 51.6 bits (122), Expect = 2e-06
Identities = 52/199 (26%), Positives = 79/199 (39%), Gaps = 28/199 (14%)
Query: 197 PSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNL----VSKHMNETSHTQGSLRI 252
P+ + N V G+S+TL CS G P P + W G+ V +N T G L I
Sbjct: 342 PTFVIQPQNTEVLVGESVTLECSATGHPPPRISWTRGDRTPLPVDPRVNIT--PSGGLYI 399
Query: 253 TNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTIT-------FLESPTSDHHWCIPF 305
N+ DSG + +C A N + + + V P T +E T D
Sbjct: 400 QNVVQGDSG-EYACSATNNIDSVHATAFIIVQALPQFTVTPQDRVVIEGQTVD----FQC 454
Query: 306 TVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKN 365
KGNP P + W G+ L+ + H+ + G L++ + G Y A N
Sbjct: 455 EAKGNPPPVIAWTKGGSQLSVDRR-----HLVLSS---GTLRISGVALHDQGQYECQAVN 506
Query: 366 EYGKDEKQISAHFMGWPGI 384
G +++ AH P +
Sbjct: 507 IIG--SQKVVAHLTVQPRV 523
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.134 0.421
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,882,149
Number of Sequences: 37866
Number of extensions: 1066813
Number of successful extensions: 5023
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 129
Number of HSP's successfully gapped in prelim test: 240
Number of HSP's that attempted gapping in prelim test: 2791
Number of HSP's gapped (non-prelim): 1726
length of query: 553
length of database: 18,247,518
effective HSP length: 107
effective length of query: 446
effective length of database: 14,195,856
effective search space: 6331351776
effective search space used: 6331351776
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.