Guide to the Human Genome
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Search of human proteins with 65293358

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|65293358 MARVEL domain containing 3 isoform 2 [Homo sapiens]
         (401 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|65293358 MARVEL domain containing 3 isoform 2 [Homo sapiens]       845   0.0  
gi|65301122 MARVEL domain containing 3 isoform 1 [Homo sapiens]       525   e-149
gi|55741709 RNA binding motif protein 25 [Homo sapiens]                77   4e-14
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]        77   4e-14
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]            74   2e-13
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ...    72   7e-13
gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]       70   3e-12
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]            69   6e-12
gi|14670268 RD RNA-binding protein [Homo sapiens]                      69   8e-12
gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti...    67   3e-11
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ...    63   5e-10
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [...    63   5e-10
gi|169167715 PREDICTED: hypothetical protein [Homo sapiens]            62   7e-10
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi...    61   2e-09
gi|4503509 eukaryotic translation initiation factor 3, subunit 1...    59   1e-08
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi...    58   1e-08
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ...    58   1e-08
gi|213385278 TNF receptor-associated factor 3 interacting protei...    58   1e-08
gi|20070262 TNF receptor-associated factor 3 interacting protein...    58   1e-08
gi|125988409 RED protein [Homo sapiens]                                57   2e-08
gi|201023341 FIP1 like 1 isoform 3 [Homo sapiens]                      55   1e-07
gi|201023339 FIP1 like 1 isoform 2 [Homo sapiens]                      55   1e-07
gi|40254978 FIP1 like 1 isoform 1 [Homo sapiens]                       55   1e-07
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi...    55   1e-07
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]           55   1e-07
gi|10190682 chromobox homolog 8 [Homo sapiens]                         55   1e-07
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]           55   1e-07
gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo sapi...    53   6e-07
gi|74272284 membrane associated guanylate kinase, WW and PDZ dom...    52   1e-06
gi|4826690 DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Homo sapiens]     51   2e-06

>gi|65293358 MARVEL domain containing 3 isoform 2 [Homo sapiens]
          Length = 401

 Score =  845 bits (2183), Expect = 0.0
 Identities = 401/401 (100%), Positives = 401/401 (100%)

Query: 1   MEDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPE 60
           MEDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPE
Sbjct: 1   MEDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPE 60

Query: 61  RDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120
           RDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR
Sbjct: 61  RDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120

Query: 121 GLTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSERYLPSTPRPGREEVEYYQS 180
           GLTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSERYLPSTPRPGREEVEYYQS
Sbjct: 121 GLTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSERYLPSTPRPGREEVEYYQS 180

Query: 181 EAEGLLECHKCKYLCTGRACCQMLEVLLNLLILACSSVSYSSTGGYTGITSLGGIYYYQF 240
           EAEGLLECHKCKYLCTGRACCQMLEVLLNLLILACSSVSYSSTGGYTGITSLGGIYYYQF
Sbjct: 181 EAEGLLECHKCKYLCTGRACCQMLEVLLNLLILACSSVSYSSTGGYTGITSLGGIYYYQF 240

Query: 241 GGAYSGFDGADGEKAQQLDVQFYQLKLPMVTVAMACSGALTALCCLFVAMGVLRVPWHCP 300
           GGAYSGFDGADGEKAQQLDVQFYQLKLPMVTVAMACSGALTALCCLFVAMGVLRVPWHCP
Sbjct: 241 GGAYSGFDGADGEKAQQLDVQFYQLKLPMVTVAMACSGALTALCCLFVAMGVLRVPWHCP 300

Query: 301 LLLVTEGLLDMLIAGGYIPALYFYFHYLSAAYGSPVCKERQALYQSKGYSGFGCSFHGAD 360
           LLLVTEGLLDMLIAGGYIPALYFYFHYLSAAYGSPVCKERQALYQSKGYSGFGCSFHGAD
Sbjct: 301 LLLVTEGLLDMLIAGGYIPALYFYFHYLSAAYGSPVCKERQALYQSKGYSGFGCSFHGAD 360

Query: 361 IGAGIFAALGIVVFALGAVLAIKGYRKVRKLKEKPAEMFEF 401
           IGAGIFAALGIVVFALGAVLAIKGYRKVRKLKEKPAEMFEF
Sbjct: 361 IGAGIFAALGIVVFALGAVLAIKGYRKVRKLKEKPAEMFEF 401


>gi|65301122 MARVEL domain containing 3 isoform 1 [Homo sapiens]
          Length = 410

 Score =  525 bits (1351), Expect = e-149
 Identities = 256/392 (65%), Positives = 290/392 (73%), Gaps = 3/392 (0%)

Query: 1   MEDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPE 60
           MEDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPE
Sbjct: 1   MEDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPE 60

Query: 61  RDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120
           RDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR
Sbjct: 61  RDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120

Query: 121 GLTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSERYLPSTPRPGREEVEYYQS 180
           GLTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSERYLPSTPRPGREEVEYYQS
Sbjct: 121 GLTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSERYLPSTPRPGREEVEYYQS 180

Query: 181 EAEGLLECHKCKYLCTGRACCQMLEVLLNLLILACSSVSYSSTGGYTGITSLGGIYYYQF 240
           EAEGLLECHKCKYLCTGR   Q++EV+LN ++L C   SY    G++   S GG +   +
Sbjct: 181 EAEGLLECHKCKYLCTGRGVVQIVEVVLNGMVLICIVASYFVLAGFSASFSSGGGFGNNY 240

Query: 241 GGAYSGFDGADGEKAQQLDVQFYQLKLPMVTVAMACSGALTALCCLFVAMGVLRVPWHCP 300
              YS F+G + E+ +QLD Q+  L+ P++   +A S  L  L    +  G         
Sbjct: 241 ---YSPFEGTELEQVRQLDQQYTILRSPLIYGGVAVSLGLGVLTMGVLLQGAKSRTMLSG 297

Query: 301 LLLVTEGLLDMLIAGGYIPALYFYFHYLSAAYGSPVCKERQALYQSKGYSGFGCSFHGAD 360
             L+TE    +L A GY   +  Y H       +  CK R+ LY  KG +   C   G D
Sbjct: 298 KWLLTEAAFSLLAAVGYCTGIGVYLHVALQINSTDTCKTRERLYARKGLTWMDCQLAGTD 357

Query: 361 IGAGIFAALGIVVFALGAVLAIKGYRKVRKLK 392
             A  FA L ++++    VLA++ YR+ ++ K
Sbjct: 358 GAAATFACLLVIMYGASVVLALRSYREQKRYK 389


>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
          Length = 843

 Score = 76.6 bits (187), Expect = 4e-14
 Identities = 55/176 (31%), Positives = 84/176 (47%), Gaps = 15/176 (8%)

Query: 8   REPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDG 67
           RE R R RER+  R    ++ R  +R RDR  D  ++R  D +R RD DRD ER  +R+ 
Sbjct: 320 RERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNK 379

Query: 68  NRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGARGLTWDAA 127
           +R R+R++ R+RERER+ +R   R+  R+           E+ R+ R +D  R       
Sbjct: 380 DRSRSREKSRDRERERERERERERERERERERERERERERERERE-REKDKKRDRE---- 434

Query: 128 APPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSERYLPSTPRPGREEVEYYQSEAE 183
                   E  E    +RK +  R+  E E   +  L +     R++   Y+ EAE
Sbjct: 435 --------EDEEDAYERRKLE--RKLREKEAAYQERLKNWEIRERKKTREYEKEAE 480



 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 30/96 (31%), Positives = 54/96 (56%)

Query: 1   MEDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPE 60
           +E+  G +E   +  E++   R    +     R R+R  +  R+R  +  R R+ +RD +
Sbjct: 291 LEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRD 350

Query: 61  RDQERDGNRDRNRDRERERERERDPDRGPRRDTHRD 96
           RD+ ++ +RDR+R+R+R+R+RER  DR   R   R+
Sbjct: 351 RDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSRE 386



 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 34/107 (31%), Positives = 60/107 (56%), Gaps = 5/107 (4%)

Query: 17  RDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDG-DRDPERDQERDGNRDRNRDR 75
           RD  ++   ++G+  ++ R      RR+R  +  R R+  +R+ ER++ER+  +++ R+R
Sbjct: 285 RDTHKKLEEEKGKK-EKERQEIEKERRERERERERERERREREREREREREREKEKERER 343

Query: 76  ERERERERD--PDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120
           ERER+R+RD   +R   RD  RD   R  E        +SR+R+ +R
Sbjct: 344 ERERDRDRDRTKERDRDRDRERDR-DRDRERSSDRNKDRSRSREKSR 389



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 32/124 (25%), Positives = 55/124 (44%), Gaps = 30/124 (24%)

Query: 2   EDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPER 61
           E  S   + R+R RE+   R    ++ R  +R R+R  +  R+R  +  R R+ ++D +R
Sbjct: 372 ERSSDRNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKR 431

Query: 62  DQERDGN----------------------------RDRNRDRERERERERDPDRGPRRDT 93
           D+E D                              R+R + RE E+E ER+ +R  RR+ 
Sbjct: 432 DREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEER--RREM 489

Query: 94  HRDA 97
            ++A
Sbjct: 490 AKEA 493



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 30/117 (25%), Positives = 51/117 (43%), Gaps = 27/117 (23%)

Query: 2   EDPSGAREP-RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPE 60
           +D S +RE  R R RER+  R    ++ R  +R R+R  +  R+R  + +++RD + D E
Sbjct: 379 KDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEE 438

Query: 61  --------------------------RDQERDGNRDRNRDRERERERERDPDRGPRR 91
                                       +ER   R+  ++ ERE ER R+  +  +R
Sbjct: 439 DAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKR 495



 Score = 33.9 bits (76), Expect = 0.27
 Identities = 46/214 (21%), Positives = 68/214 (31%), Gaps = 52/214 (24%)

Query: 11  RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGN-------------------- 50
           R R RER+  R    ++ R  +R R+R  D +R R  D                      
Sbjct: 399 REREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQ 458

Query: 51  ------------RRRDGDRDPERDQERDGNRDRNRDRERERERERDPDRGP--------- 89
                       + R+ +++ ER++ER     +   R +E   + D DR           
Sbjct: 459 ERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSAL 518

Query: 90  -------RRDTHRDAGPRAGEHGVWEKPRQSRTRDGARGLTWDAAAPPGPAPWEAPEPPQ 142
                   ++   D   R  E    E+ RQ    +G      D  A       EA    Q
Sbjct: 519 QKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHP----DPDAELQRMEQEAERRRQ 574

Query: 143 PQRKGDPGRRRPESEPPSERYLPSTPRPGREEVE 176
           PQ K +P     E E   +      P    EE E
Sbjct: 575 PQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPE 608



 Score = 31.6 bits (70), Expect = 1.3
 Identities = 23/107 (21%), Positives = 43/107 (40%), Gaps = 22/107 (20%)

Query: 2   EDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDR-----------------PGDPRRK 44
           +DP   R    + R RD  +    D+    DR R++                 P    ++
Sbjct: 508 DDPKYYRGSALQKRLRDREKEMEADE---RDRKREKEELEEIRQRLLAEGHPDPDAELQR 564

Query: 45  RSSDGNRRRDGD--RDPERDQERDGNRDRNRDRERERERERDPDRGP 89
              +  RRR     ++PE ++E +  +++   RE   E E +P++ P
Sbjct: 565 MEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKP 611


>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
          Length = 1564

 Score = 76.6 bits (187), Expect = 4e-14
 Identities = 55/167 (32%), Positives = 79/167 (47%), Gaps = 19/167 (11%)

Query: 8   REPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDG 67
           R+ RAR R+R+  R       R  +R R+R  D  R++  +  R R  +R+ ER++ERD 
Sbjct: 672 RDERARERDRERER------DRERERERERERDREREKERELERERAREREREREKERDR 725

Query: 68  NRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGARGLTWDAA 127
            RDR+RD +RERERER+ DR   R+  R+   R  E     +  + R R+ AR    +  
Sbjct: 726 ERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERERARERDKERE 785

Query: 128 APPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSERYLPSTPRPGREE 174
                  WE  +      KG   RR    E   +R     PR G +E
Sbjct: 786 R---QRDWEDKD------KGRDDRREKREEIREDR----NPRDGHDE 819



 Score = 67.0 bits (162), Expect = 3e-11
 Identities = 53/166 (31%), Positives = 76/166 (45%), Gaps = 35/166 (21%)

Query: 7   ARE-PRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRS-SDGNRRRDGDRDPERDQE 64
           ARE  R R +ERD  R    D  R  +R R+R  +  R+R   +  R R+ +R+ ER++E
Sbjct: 712 AREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERE 771

Query: 65  RDGNRDRNRDRERERERE-------RDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRD 117
           R+  R R RD+ERER+R+       RD  R  R +   D  PR G        R+S+ R 
Sbjct: 772 RERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDG-----HDERKSKKRY 826

Query: 118 GARGLTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSERY 163
              G          P+P ++P            +RR E  P S+ Y
Sbjct: 827 RNEG---------SPSPRQSP------------KRRREHSPDSDAY 851



 Score = 66.2 bits (160), Expect = 5e-11
 Identities = 38/113 (33%), Positives = 62/113 (54%), Gaps = 6/113 (5%)

Query: 8   REPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDG 67
           R+ R   R  D       ++ R  DR R+R  +  R+R  + +R R+ +R+ ER++ R+ 
Sbjct: 656 RDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERARER 715

Query: 68  NRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120
            R+R ++R+RER+R+RD DR   R+  RD   R  E    E+ R+ R R+  R
Sbjct: 716 EREREKERDRERDRDRDHDRERERERERD---REKER---EREREERERERER 762



 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 43/122 (35%), Positives = 60/122 (49%), Gaps = 10/122 (8%)

Query: 8   REPRARPRERDPGRRPHPDQGRTHDRPRD-RPGDPRRKRSSDGNRRRDG-------DRDP 59
           R+ R + R+    RR H ++ R  +R RD RP  P R +  +    RD        DR  
Sbjct: 611 RDNRDQARDSSFERR-HGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVD 669

Query: 60  ERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRD-AGPRAGEHGVWEKPRQSRTRDG 118
           +R  ER   RDR R+R+RERERER+ +R   R+  R+    RA E     +  + R RD 
Sbjct: 670 DRRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDR 729

Query: 119 AR 120
            R
Sbjct: 730 DR 731



 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 40/118 (33%), Positives = 62/118 (52%), Gaps = 10/118 (8%)

Query: 8   REPRARPRERDPGRRPHPDQG-RTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERD 66
           R+ R     R  GR    ++  R  +R  DR  D R +R+ + +R R+ DR+ ER++ER+
Sbjct: 637 RDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERE 696

Query: 67  GNRDRNRDRE----RERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120
            +R+R ++RE    R RERER  +R   RD  RD   R  +H    +  + R R+  R
Sbjct: 697 RDREREKERELERERARERER--EREKERDRERD---RDRDHDRERERERERDREKER 749



 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 39/122 (31%), Positives = 61/122 (50%), Gaps = 12/122 (9%)

Query: 5    SGAREPRARPRERDP---GRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPER 61
            SG+ + R R +ERD     R    ++  T  R  DR  D    R+ D +R R+ +R+ ER
Sbjct: 1290 SGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERER 1349

Query: 62   DQERDGNRDRNR------DRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRT 115
            D+ RD +R+R R      +R+R+R+R+R  +        R      GEH   E+  +S +
Sbjct: 1350 DKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEH---ERDLESTS 1406

Query: 116  RD 117
            RD
Sbjct: 1407 RD 1408



 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 36/96 (37%), Positives = 49/96 (51%), Gaps = 7/96 (7%)

Query: 3    DPSGAREPRARPRERDPGRRPHPDQGRTHDRPR----DR-PGDPRRKRSSDGNRRRDGDR 57
            D   +R   +R    +  R+ H   G    R R    DR   D  R+R     R+R+ DR
Sbjct: 1266 DRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDR 1325

Query: 58   DPERDQERDGNRDRNRDRERERERE--RDPDRGPRR 91
            D ++D  R+ +RDR R+RERERER+  RD DR   R
Sbjct: 1326 DADKDWPRNRDRDRLRERERERERDKRRDLDRERER 1361



 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 40/119 (33%), Positives = 56/119 (47%), Gaps = 15/119 (12%)

Query: 10  PRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNR 69
           PR R   R+ GR  H    ++HDR  +R  D R KR    +R +D   + E +Q++  +R
Sbjct: 389 PRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKR----DREKDSREEREYEQDQSSSR 444

Query: 70  DRNRDRE----RERERERDP-DRGPRRDTH-----RDAGPRAGEHGVWEKPRQSR-TRD 117
           D   DRE    R+R   RD  DR   RD+      R+    + +      PR SR TRD
Sbjct: 445 DHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRD 503



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 38/116 (32%), Positives = 51/116 (43%), Gaps = 21/116 (18%)

Query: 3   DPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERD 62
           D    RE     RER              +R R+R  +  R+R  +  R RD +R+ +RD
Sbjct: 744 DREKEREREREERER--------------ERERERERERERERERERARERDKERERQRD 789

Query: 63  QERDGNRDRNRDRERERERERDPDRGPRRDTH--RDAGPRAGEHGVWEKPRQSRTR 116
            E   ++D+ RD  RE+  E   DR P RD H  R +  R    G    PRQS  R
Sbjct: 790 WE---DKDKGRDDRREKREEIREDRNP-RDGHDERKSKKRYRNEGS-PSPRQSPKR 840



 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 45/191 (23%), Positives = 77/191 (40%), Gaps = 19/191 (9%)

Query: 11  RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRD 70
           R R RER+  R    ++ R  D+ R+R  D   K     +RR   +   E    RDG+ +
Sbjct: 760 RERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDE 819

Query: 71  RNRDRERERERERDPDRGPRR--------DTHRDAGPRAGEHGVWE---KPRQSRTRDGA 119
           R   +    E    P + P+R        D +     +  +H +     +P++SR+   +
Sbjct: 820 RKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPS 879

Query: 120 RGLTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSERYLPSTPRPGREEVEYYQ 179
             LT D         W+  E  +P+RK +  RR  E E   +       R   E +E  +
Sbjct: 880 H-LTEDR-----QGRWK-EEDRKPERK-ESSRRYEEQELKEKVSSVDKQREQTEILESSR 931

Query: 180 SEAEGLLECHK 190
             A+ ++  H+
Sbjct: 932 MRAQDIIGHHQ 942



 Score = 36.6 bits (83), Expect = 0.041
 Identities = 30/109 (27%), Positives = 44/109 (40%), Gaps = 15/109 (13%)

Query: 57  RDPERDQERDGNRDRNRDRERERERERDP--------DRGPRRDTHRDAGPRAG----EH 104
           +D   ++ RDG +DR RD ER+RE+   P           P    H  +  ++G     H
Sbjct: 287 KDRIEEKTRDG-KDRGRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRH 345

Query: 105 GVWEKPRQSRTRDGARGLTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRR 153
                PR+ RT   +   T         +P+ +     PQRK  P R R
Sbjct: 346 S--PSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHR 392



 Score = 35.8 bits (81), Expect = 0.071
 Identities = 45/168 (26%), Positives = 65/168 (38%), Gaps = 24/168 (14%)

Query: 2   EDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDR-PGDPRRKRSSDGNRRRDGDRDPE 60
           ED  G R+     RE    R    DQ  + D   DR P D R +R +   R R   RD  
Sbjct: 418 EDTRGKRDREKDSREE---REYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSR 474

Query: 61  --------RDQERDGNRDRN-------RDRERERERE-RDPDRGPRRDTHRDAGPRAGEH 104
                   RD  RD    R+       RD    R+RE RD  R  + DT+ +     G +
Sbjct: 475 DMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHR--KEDTYPEESRSYGRN 532

Query: 105 GVWEKPRQSRTRDGARGLTWDAAAPP--GPAPWEAPEPPQPQRKGDPG 150
            + E+  ++  R+ +R  +         G +    PE P+   +G  G
Sbjct: 533 HLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRG 580



 Score = 33.5 bits (75), Expect = 0.35
 Identities = 40/150 (26%), Positives = 49/150 (32%), Gaps = 57/150 (38%)

Query: 8   REPRARPRERDPG--------------------------------RRPHPDQGRTHDRPR 35
           RE R +PR   P                                 R P P   RT   P 
Sbjct: 308 REKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPL 367

Query: 36  DRP---------GDPRRKRSSDGNR---RRDG-----------DRDPERDQERDGNRDRN 72
            R            P+RK+S   +R   R  G           DR  ER ++  G RDR 
Sbjct: 368 RRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDRE 427

Query: 73  RDRERERERERDPDRGPRRDTHRDAGPRAG 102
           +D   ERE E+  D+   RD   D  PR G
Sbjct: 428 KDSREEREYEQ--DQSSSRDHRDDREPRDG 455



 Score = 33.1 bits (74), Expect = 0.46
 Identities = 33/99 (33%), Positives = 46/99 (46%), Gaps = 15/99 (15%)

Query: 39   GDPRRKRSSDGNRRRDGDR---DPERDQE---RDGNRD-RNRDRER-----ERERERDPD 86
            G+P R  SSD    R        PE D++   R G+ D R+R +ER     +RERER+  
Sbjct: 1257 GEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERR 1316

Query: 87   RGPRRDTHRDAG---PRAGEHGVWEKPRQSRTRDGARGL 122
               +R+  RDA    PR  +     +  + R RD  R L
Sbjct: 1317 DTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRDL 1355



 Score = 29.6 bits (65), Expect = 5.1
 Identities = 21/80 (26%), Positives = 37/80 (46%), Gaps = 8/80 (10%)

Query: 33  RPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDRNRDRERERERERDPDRGPRRD 92
           R  +RP    R+R    N+R+D D +P++    + +    ++  R R RE++  +  +  
Sbjct: 76  RSPERPTGDLRERMK--NKRQDVDTEPQKRNTEESSSPVRKESSRGRHREKEDIKITKER 133

Query: 93  THRDAGPRAGEHGV-WEKPR 111
           T     P + E  V WE  R
Sbjct: 134 T-----PESEEENVEWETNR 148



 Score = 29.6 bits (65), Expect = 5.1
 Identities = 20/46 (43%), Positives = 25/46 (54%), Gaps = 2/46 (4%)

Query: 40  DPRRKRSSDGNRRRDGDRDPERDQERDGNRDRNR-DRERERERERD 84
           D    RSS   R R  +RD  RDQ RD + +R   +R+R   RERD
Sbjct: 594 DSWETRSSYPERDRYPERD-NRDQARDSSFERRHGERDRRDNRERD 638


>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 290

 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 47/153 (30%), Positives = 74/153 (48%), Gaps = 8/153 (5%)

Query: 11  RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRD 70
           + R RERD GR    D+ R  +R R    D   +R ++  R RD +R+ ++++E + +RD
Sbjct: 131 KGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRD 190

Query: 71  RNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKP-RQSRTRDGARGLTWDAAAP 129
           R RD E+ERER+ D +R  +R T  +        G  E   R+ R RD  RG   D    
Sbjct: 191 RQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRER- 249

Query: 130 PGPAPWEAPEPPQPQRKGDPGRRRPESEPPSER 162
                 +  E  + +RK +  + R E +   +R
Sbjct: 250 ------DRKEERKKERKKERKKERKEKKKEEKR 276



 Score = 63.5 bits (153), Expect = 3e-10
 Identities = 40/132 (30%), Positives = 63/132 (47%), Gaps = 11/132 (8%)

Query: 2   EDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNR---------- 51
           +D  G RE     RERD  R    ++    DR R R  +  R+R +D  R          
Sbjct: 159 KDRDGQRETETE-RERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTER 217

Query: 52  RRDGDRDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPR 111
           +R+ DR+ ER+ +R   R R+RDR +ER+RERD     +++  ++      E    EK R
Sbjct: 218 QRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRR 277

Query: 112 QSRTRDGARGLT 123
           + + R    G++
Sbjct: 278 EDKKRKWGEGIS 289



 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 39/121 (32%), Positives = 63/121 (52%), Gaps = 5/121 (4%)

Query: 3   DPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERD 62
           D    R+   R +E++  R    ++    +R R+R     R+R  D  R R+ DRD E++
Sbjct: 93  DRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKE 152

Query: 63  QERDGNRDRN--RDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQS-RTRDGA 119
           +ER   +DR+  R+ E ERER+R+ ++   R+T RD   +       E+ RQ+ R RD  
Sbjct: 153 RERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEK--ERERQTDRERDRQ 210

Query: 120 R 120
           R
Sbjct: 211 R 211



 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 34/88 (38%), Positives = 50/88 (56%), Gaps = 12/88 (13%)

Query: 13  RPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDG--------DRDPERDQE 64
           R RERD  R    ++ R  DR RDR    RR++  + NR RD         DR+ E+ + 
Sbjct: 77  RQRERDRVREK-TEKERDRDRKRDRE---RRRKEKETNRNRDREKQTEIERDREREKQKG 132

Query: 65  RDGNRDRNRDRERERERERDPDRGPRRD 92
           R+  RDR R+RER+R+RE++ +R   +D
Sbjct: 133 RERERDRGRERERDRDREKERERQTEKD 160



 Score = 52.4 bits (124), Expect = 7e-07
 Identities = 35/110 (31%), Positives = 58/110 (52%), Gaps = 7/110 (6%)

Query: 14  PRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDRNR 73
           PR    G+      G    R RDR  + + ++  D +R+RD +R   R +E++ NR+R+R
Sbjct: 60  PRSWGLGQAHKDADGDDRQRERDRVRE-KTEKERDRDRKRDRER---RRKEKETNRNRDR 115

Query: 74  DRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRT---RDGAR 120
           +++ E ER+R+ ++   R+  RD G         EK R+ +T   RDG R
Sbjct: 116 EKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQR 165


>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
           sapiens]
          Length = 600

 Score = 72.4 bits (176), Expect = 7e-13
 Identities = 53/167 (31%), Positives = 78/167 (46%), Gaps = 7/167 (4%)

Query: 11  RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRD 70
           R R RER+       ++ R  DR RDR     R+R     R R  +R+ ERD+ER+  RD
Sbjct: 208 RGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERD 267

Query: 71  RNRDRE-RERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGARGLTWDAAAP 129
           R+RDR+ R++ERER  DR  +R T RD      E     + ++ R R+  R    +    
Sbjct: 268 RDRDRDRRQKERERQTDRKRQRRTERDR-----ETERKRERQRERERERERNRKRERERE 322

Query: 130 PGPAPWEAPEPPQPQRKGDPGRRRPESEPPSERYLPSTPRPGREEVE 176
                    E  + + K    +R+ ++E   ER    T R GR + E
Sbjct: 323 RERERERQRETERDREKERERKRKRQTEMDRERN-RQTGREGRRQAE 368



 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 54/189 (28%), Positives = 82/189 (43%), Gaps = 34/189 (17%)

Query: 11  RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRD 70
           R R RER+  R+   ++    +R RDR  D +++R     + RDG R+ E+ +ER+ +R+
Sbjct: 369 RERERERERDRQSARER---EERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRE 425

Query: 71  --RNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDG---------A 119
             R R+R RERE+++  +R   R T R AG +     ++  P     R G          
Sbjct: 426 SERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNRPT 485

Query: 120 RGLTW-----DAAAPPGPAPWEAP--------------EPPQPQRKGDPGR-RRPESEPP 159
           RG+ W     D  A     PW  P              EP   +++G  G  RRP     
Sbjct: 486 RGIRWKSSPEDPKAASTRFPWGRPAKASRGRVAGRRRWEPRLGEKRGQGGEGRRPSGGFG 545

Query: 160 SERYLPSTP 168
           +E  L   P
Sbjct: 546 TENPLSQAP 554



 Score = 66.6 bits (161), Expect = 4e-11
 Identities = 39/114 (34%), Positives = 65/114 (57%), Gaps = 5/114 (4%)

Query: 8   REPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDG 67
           R  + R R+ D  R+   ++ R  +R R+R  +  R+R  +  R R+ +R+ ER+++R+ 
Sbjct: 274 RRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRET 333

Query: 68  NRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQ-SRTRDGAR 120
            RDR ++RER+R+R+ + DR   R T R+ G R  E    E+ R+  R R  AR
Sbjct: 334 ERDREKERERKRKRQTEMDRERNRQTGRE-GRRQAER---ERERERERDRQSAR 383



 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 41/117 (35%), Positives = 62/117 (52%), Gaps = 9/117 (7%)

Query: 8   REPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQER-- 65
           R  + R R+RD  R    D+ +  +R  DR  D  R+R  + NR+++ +R+ ER+ ER  
Sbjct: 82  RREKDRHRKRDRHRERQRDREKERERQTDRERD--RQREKERNRQKERERETEREGERGR 139

Query: 66  ----DGNRDRNRDRERERERERDPDRGPRRDTHRD-AGPRAGEHGVWEKPRQSRTRD 117
               DG R+R R R+ E+ERER  DR  +R T R+    R  E    E+  + R R+
Sbjct: 140 DRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQRE 196



 Score = 63.2 bits (152), Expect = 4e-10
 Identities = 33/116 (28%), Positives = 59/116 (50%)

Query: 2   EDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPER 61
           E  +  +  R R ++R   R  H ++ R  ++ R+R  D  R R  +  R R  +R+ E 
Sbjct: 72  ERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERET 131

Query: 62  DQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRD 117
           ++E +  RDR  D +RERER+RD ++   R T R+   +   +   E+ R+   ++
Sbjct: 132 EREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQE 187



 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 40/118 (33%), Positives = 58/118 (49%), Gaps = 5/118 (4%)

Query: 2   EDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPER 61
           +D  G    R R +ER+  R     +  T DR R+R  +  R R  D +R R  DR+ ER
Sbjct: 47  KDADGDDRERNRQKERERRREKRQTERET-DRKRERRREKDRHRKRDRHRERQRDREKER 105

Query: 62  ----DQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRT 115
               D+ERD  R++ R+R++ERERE + +    RD   D           EK R+ +T
Sbjct: 106 ERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQT 163



 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 27/107 (25%), Positives = 60/107 (56%)

Query: 11  RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRD 70
           R R RE++  R+   ++ R  ++ R+R  +  R+   +G R RD   D +R++ER  + +
Sbjct: 97  RQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAE 156

Query: 71  RNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRD 117
           + R+R+ +RER+R  +R  +++  R+   +       ++ ++++T D
Sbjct: 157 KERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTED 203



 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 40/119 (33%), Positives = 61/119 (51%), Gaps = 12/119 (10%)

Query: 2   EDPSGAREPRARPRERDPGRRP---HPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRD 58
           E     +E R R R+R+   +    H ++GR  +R R+   +  RKR +D  R RD  R 
Sbjct: 180 EREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTD--RERDRQRK 237

Query: 59  PERDQERDGNRDR--NRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRT 115
            ER++E+   R+R   R+ ER++ERER+ DR   RD  +    R       ++ RQ RT
Sbjct: 238 TEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQ-----TDRKRQRRT 291



 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 34/113 (30%), Positives = 54/113 (47%)

Query: 8   REPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDG 67
           +  R R RER+  R    ++ R  +R R+R  +  R R  +  R+R    + +R++ R  
Sbjct: 300 KRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQT 359

Query: 68  NRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120
            R+  R  ERERERER+ DR   R+       R  +     + +  + RDG R
Sbjct: 360 GREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQR 412



 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 34/110 (30%), Positives = 54/110 (49%), Gaps = 2/110 (1%)

Query: 11  RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRD 70
           R   RERD  R    ++ +  +R  +R G+  R R +DG R R+  RD E+++ER    D
Sbjct: 107 RQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQ--TD 164

Query: 71  RNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120
           R R R+ ER R+++ +R   R   R+   +  +    E     R R+  R
Sbjct: 165 RERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERER 214



 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 35/108 (32%), Positives = 54/108 (50%), Gaps = 2/108 (1%)

Query: 8   REPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDG 67
           RE R   RE D  R    ++ R   R RDR  + +R R  +  R+ D +RD +R++ER+ 
Sbjct: 66  REKRQTERETDRKRERRREKDR--HRKRDRHRERQRDREKERERQTDRERDRQREKERNR 123

Query: 68  NRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRT 115
            ++R R+ ERE ER RD     +R+  R            ++ RQ +T
Sbjct: 124 QKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQT 171



 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 38/115 (33%), Positives = 58/115 (50%), Gaps = 12/115 (10%)

Query: 11  RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRD 70
           R   RE + GR    D  R  +R RD   +  R+R +D  R+R  +R+ ++++ER+ NR 
Sbjct: 129 RETEREGERGRDRQTDGQRERERQRD--AEKERERQTDRERQRQTERNRQKEREREKNRQ 186

Query: 71  RNRDRERERERE-----RDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120
             R+RER+RE+E     R  +RG  R+  R+      E     K +  R RD  R
Sbjct: 187 ERRERERQREKENKTEDRHSERGRERERERET-----ETETERKRQTDRERDRQR 236



 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 45/182 (24%), Positives = 77/182 (42%), Gaps = 8/182 (4%)

Query: 2   EDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPER 61
           E  +  +  R   R+R+  R+    + R  +R R+R  +  R+R  +  R+R+ +RD E+
Sbjct: 280 ERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREK 339

Query: 62  DQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGARG 121
           ++ER   R    DRER R+  R+  R   R+  R+           E+  + R RD  R 
Sbjct: 340 ERERKRKRQTEMDRERNRQTGREGRRQAERERERER--ERDRQSAREREERERDRDRDRQ 397

Query: 122 LTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSERYLPSTPRPGREEVEYYQSE 181
              +          +     + QR+ +  R   ESE   ER      + GRE     Q++
Sbjct: 398 KERERQTEKDR---DGQRETEKQREREKDR---ESERGRERGREREKQKGRERDRERQTD 451

Query: 182 AE 183
            +
Sbjct: 452 RQ 453



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 34/110 (30%), Positives = 51/110 (46%), Gaps = 5/110 (4%)

Query: 17  RDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDRNRDRE 76
           R PG +  P +       +D  GD R +       RR   R  ER+ +R   R R +DR 
Sbjct: 29  RRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRH 88

Query: 77  RE----RERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRT-RDGARG 121
           R+    RER+RD ++   R T R+   +  +    +K R+  T R+G RG
Sbjct: 89  RKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERG 138



 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 27/75 (36%), Positives = 41/75 (54%), Gaps = 13/75 (17%)

Query: 32 DRPRDRPGD---PRRKRSSDGNRRRDGDRDPERDQERDGNRDRNRDR-------ERERER 81
          D  R RPG    PRR+     ++  DGD   +R++ R   R+R R++       +R+RER
Sbjct: 25 DFSRRRPGSQESPRRRGLGQAHKDADGD---DRERNRQKERERRREKRQTERETDRKRER 81

Query: 82 ERDPDRGPRRDTHRD 96
           R+ DR  +RD HR+
Sbjct: 82 RREKDRHRKRDRHRE 96


>gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]
          Length = 2240

 Score = 70.5 bits (171), Expect = 3e-12
 Identities = 52/127 (40%), Positives = 70/127 (55%), Gaps = 11/127 (8%)

Query: 1    MEDPSG-AREPRARPRERDPGRRPHPDQGRTHDRPR--DRPGDPRRKRSSDGNRRRDGDR 57
            +E+P    R    R RER+ GR  +  + R  DRPR  DR  D    R  D NR R  +R
Sbjct: 2100 LEEPDAQGRASEDRRRERERGR--NWSRERDWDRPREWDRHRDKDSSRDWDRNRERSANR 2157

Query: 58   DPERDQER----DGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQS 113
            D ER+ +R    D +R+R+R+RERER+R RD DR   R+  RD   R  E G   K R S
Sbjct: 2158 DREREADRGKEWDRSRERSRNRERERDRRRDRDRSRSRERDRDKA-RDRERGRDRKDR-S 2215

Query: 114  RTRDGAR 120
            ++++ AR
Sbjct: 2216 KSKESAR 2222



 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 44/107 (41%), Positives = 56/107 (52%), Gaps = 6/107 (5%)

Query: 13   RPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDRN 72
            RPRE D  R    D  R  DR R+R  +  R+R +D  R ++ DR  ER + R+  RDR 
Sbjct: 2131 RPREWD--RHRDKDSSRDWDRNRERSANRDREREAD--RGKEWDRSRERSRNRERERDRR 2186

Query: 73   RDRERERERERDPDRGPRRDTHRDAGPR--AGEHGVWEKPRQSRTRD 117
            RDR+R R RERD D+   R+  RD   R  + E     KP  SR  D
Sbjct: 2187 RDRDRSRSRERDRDKARDRERGRDRKDRSKSKESARDPKPEASRASD 2233



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 37/91 (40%), Positives = 48/91 (52%), Gaps = 9/91 (9%)

Query: 13   RPRER---DPGRRP--HPD-QGR-THDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQER 65
            R RER    P  +P   PD QGR + DR R+R       R  D +R R+ DR  ++D  R
Sbjct: 2086 RQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWDRPREWDRHRDKDSSR 2145

Query: 66   DGNRDRNRDRERERERERDPDRGPRRDTHRD 96
            D +R+R R   R+RERE   DRG   D  R+
Sbjct: 2146 DWDRNRERSANRDRERE--ADRGKEWDRSRE 2174



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 37/116 (31%), Positives = 49/116 (42%), Gaps = 9/116 (7%)

Query: 19   PGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDP------ERDQERDGNRDRN 72
            PG+ P  D        R+  G   R ++ +G +R   D  P      E D +   + DR 
Sbjct: 2055 PGQGPEADGQWASADFREGKGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRR 2114

Query: 73   RDRERERE--RERDPDRGPRRDTHRDA-GPRAGEHGVWEKPRQSRTRDGARGLTWD 125
            R+RER R   RERD DR    D HRD    R  +        + R R+  RG  WD
Sbjct: 2115 RERERGRNWSRERDWDRPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWD 2170


>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 202

 Score = 69.3 bits (168), Expect = 6e-12
 Identities = 34/86 (39%), Positives = 52/86 (60%)

Query: 11  RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRD 70
           R R R+R+  R+   ++ +  DR R R  D  R+R+  G R RD   + ERD+ER+  R 
Sbjct: 80  RERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQ 139

Query: 71  RNRDRERERERERDPDRGPRRDTHRD 96
           R R+R+R+RER+R+ DR  +R   R+
Sbjct: 140 RERERQRQRERKRETDRERQRWAERE 165



 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 35/84 (41%), Positives = 50/84 (59%)

Query: 13  RPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDRN 72
           R  ER   R+   ++ R  DR RD+  D  RKR +D NR R+     ERD++ +  RDR 
Sbjct: 74  RETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRE 133

Query: 73  RDRERERERERDPDRGPRRDTHRD 96
           R+R+R+RERER   R  +R+T R+
Sbjct: 134 RERQRQRERERQRQRERKRETDRE 157



 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 38/88 (43%), Positives = 51/88 (57%), Gaps = 4/88 (4%)

Query: 11  RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRD 70
           R R +ERD  R+   +  R  +R R+R     RKR +D  R RD DRD ER +E D NR+
Sbjct: 56  RERQKERDRQRQRERETERETERQRERQRQRERKRQTD--RERDKDRDRERKRETDRNRE 113

Query: 71  RNRD--RERERERERDPDRGPRRDTHRD 96
           RNR   RER+++ ER+ DR   R   R+
Sbjct: 114 RNRKGGRERDKQTERERDRERERQRQRE 141



 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 42/156 (26%), Positives = 74/156 (47%), Gaps = 1/156 (0%)

Query: 8   REPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDG 67
           RE R R R+R   R    D+ +  +R ++R    +R+R ++    R  +R  +R+++R  
Sbjct: 33  RENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQT 92

Query: 68  NRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQ-SRTRDGARGLTWDA 126
           +R+R++DR+RER+RE D +R   R   R+   +       E+ RQ  R R+  R      
Sbjct: 93  DRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKR 152

Query: 127 AAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSER 162
                   W   E  + +RK +  + R E +   +R
Sbjct: 153 ETDRERQRWAEREERKKERKKERKKERKEKKKEEKR 188



 Score = 59.7 bits (143), Expect = 5e-09
 Identities = 40/129 (31%), Positives = 63/129 (48%), Gaps = 14/129 (10%)

Query: 2   EDPSGAREPRARPRERD-------PGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRD 54
           E   G    R R R+R+         R    D+ R  DR  DR  +  R++  D  R+R+
Sbjct: 10  ETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRE 69

Query: 55  GD--RDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQ 112
            +  R+ ER +ER   R+R R  +RER+++RD +R    D +R+   + G     E+ +Q
Sbjct: 70  RETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGR----ERDKQ 125

Query: 113 S-RTRDGAR 120
           + R RD  R
Sbjct: 126 TERERDRER 134



 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 30/86 (34%), Positives = 48/86 (55%), Gaps = 5/86 (5%)

Query: 16 ERDPGRRPHPDQGRTHDRPRDRPGD-----PRRKRSSDGNRRRDGDRDPERDQERDGNRD 70
          ER   R+   D+G+  +R RDR  +      R  R    +R R+ DR  +R++ER+  ++
Sbjct: 2  ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61

Query: 71 RNRDRERERERERDPDRGPRRDTHRD 96
          R+R R+RERE ER+ +R   R   R+
Sbjct: 62 RDRQRQRERETERETERQRERQRQRE 87



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 37/117 (31%), Positives = 55/117 (47%), Gaps = 8/117 (6%)

Query: 11  RARPRERDPGRRPHPDQGRTHDRP-------RDRPGDPRRKRSSDGNRRRDGDRDPERDQ 63
           R R RE D G+    ++ R  +R        R R  D  R+R    +R ++ +R  ERD+
Sbjct: 5   RERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDR 64

Query: 64  ERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120
           +R   R+  R+ ER+RER+R  +R  + D  RD   R  E        + R R G R
Sbjct: 65  QRQRERETERETERQRERQRQRERKRQTDRERDK-DRDRERKRETDRNRERNRKGGR 120



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 31/97 (31%), Positives = 49/97 (50%), Gaps = 18/97 (18%)

Query: 42  RRKRSSDGNRRRDGDRDPERDQERDG-----NRDRNRDR------------ERERERERD 84
           +R+R  + +R ++ +R+ +R +ER+      NR R RDR            ERER++ERD
Sbjct: 4   QRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERD 63

Query: 85  PDRGPRRDTHRDAGPRAGEHGVWEKPRQS-RTRDGAR 120
             R   R+T R+   +       E+ RQ+ R RD  R
Sbjct: 64  RQRQRERETERETERQRERQRQRERKRQTDRERDKDR 100



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 7/79 (8%)

Query: 6   GAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQER 65
           G    +   RERD  R       R   R R+R     RKR +D  R+R  +R+ ER +ER
Sbjct: 119 GRERDKQTERERDRERE------RQRQRERERQRQRERKRETDRERQRWAERE-ERKKER 171

Query: 66  DGNRDRNRDRERERERERD 84
              R + R  +++ E+ R+
Sbjct: 172 KKERKKERKEKKKEEKRRE 190


>gi|14670268 RD RNA-binding protein [Homo sapiens]
          Length = 380

 Score = 68.9 bits (167), Expect = 8e-12
 Identities = 47/107 (43%), Positives = 58/107 (54%), Gaps = 19/107 (17%)

Query: 2   EDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPER 61
           E+ SGA    + PR R         + R+H+R RDR  D  R R       RD DRD ER
Sbjct: 171 EERSGAHSSASPPRSRS--------RDRSHERNRDRDRDRERDRD------RDRDRDRER 216

Query: 62  DQERDGNRDRNRDRERERERERDPDR---GPRRDTHRDAGPRAGEHG 105
           D++RD  RDR+RDRER+R+RERD DR   GP R +      RA   G
Sbjct: 217 DRDRD--RDRDRDRERDRDRERDRDRDREGPFRRSDSFPERRAPRKG 261



 Score = 66.6 bits (161), Expect = 4e-11
 Identities = 35/91 (38%), Positives = 51/91 (56%)

Query: 2   EDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPER 61
           E+  G       PR  D G         +   PR R  D   +R+ D +R R+ DRD +R
Sbjct: 151 EEAEGPGAGDGPPRSFDWGYEERSGAHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDR 210

Query: 62  DQERDGNRDRNRDRERERERERDPDRGPRRD 92
           D++R+ +RDR+RDR+R+RER+RD +R   RD
Sbjct: 211 DRDRERDRDRDRDRDRDRERDRDRERDRDRD 241



 Score = 49.3 bits (116), Expect = 6e-06
 Identities = 27/72 (37%), Positives = 37/72 (51%)

Query: 25  PDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDRNRDRERERERERD 84
           P  G    R  D   + R    S  +  R   RD   ++ RD +RDR RDR+R+R+R+R+
Sbjct: 156 PGAGDGPPRSFDWGYEERSGAHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRE 215

Query: 85  PDRGPRRDTHRD 96
            DR   RD  RD
Sbjct: 216 RDRDRDRDRDRD 227



 Score = 45.4 bits (106), Expect = 9e-05
 Identities = 26/84 (30%), Positives = 39/84 (46%)

Query: 13  RPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDRN 72
           R RE  P        G     PR        +  +  +      R  +R  ER+ +RDR+
Sbjct: 142 RLRELGPDGEEAEGPGAGDGPPRSFDWGYEERSGAHSSASPPRSRSRDRSHERNRDRDRD 201

Query: 73  RDRERERERERDPDRGPRRDTHRD 96
           R+R+R+R+R+RD +R   RD  RD
Sbjct: 202 RERDRDRDRDRDRERDRDRDRDRD 225


>gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial
           [Homo sapiens]
          Length = 213

 Score = 67.0 bits (162), Expect = 3e-11
 Identities = 49/157 (31%), Positives = 71/157 (45%), Gaps = 13/157 (8%)

Query: 11  RARPRERDPGR-RPHPDQGRTHDR--PRDRPGDPRRKRSSDGNRRRDG--DRDPERDQER 65
           R R R R+  R R    + +T DR   RDR  D  R R  D +R R+   DR+ ER +ER
Sbjct: 19  RQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRER 78

Query: 66  DGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGARGLTWD 125
           + +RDR R+ ERER++ER+ DR    D  R          V ++ R+ +   G    T  
Sbjct: 79  ERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQT-- 136

Query: 126 AAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSER 162
                     +     Q +R+ + GR R   +   ER
Sbjct: 137 ------DRETDRERERQAERERETGRERKTEDRHRER 167



 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 35/107 (32%), Positives = 52/107 (48%)

Query: 11  RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRD 70
           R R RERD  R+   ++ R  +R  DR  +  R+R     R  +  RD ER+++++  R+
Sbjct: 74  RQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRE 133

Query: 71  RNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRD 117
           R  DRE +RERER  +R       R    R  E     K  + R R+
Sbjct: 134 RQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRE 180



 Score = 55.5 bits (132), Expect = 9e-08
 Identities = 39/107 (36%), Positives = 53/107 (49%), Gaps = 14/107 (13%)

Query: 20  GRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDG--NRDRNRDRER 77
           GR  H +   T DR R+R  +  R+R      + + DR  ERD++RD   NR+R+RDRER
Sbjct: 7   GRHTHTET-ETMDRQRERRRETDRERDRAKESKTE-DRHSERDRQRDRERNRERDRDRER 64

Query: 78  E----------RERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSR 114
           E          RERERD DR    +  RD       H   ++ RQ +
Sbjct: 65  EKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQ 111



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 27/89 (30%), Positives = 45/89 (50%)

Query: 8   REPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDG 67
           R   ++  +R   R    D+ R  +R RDR  + +  R  +  R R+ DRD +R+ ER+ 
Sbjct: 33  RAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDRQRETERER 92

Query: 68  NRDRNRDRERERERERDPDRGPRRDTHRD 96
           +++R  DR  E +RER   +    +  RD
Sbjct: 93  DKERETDRHTETDRERQKQKEREMERVRD 121



 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 32/100 (32%), Positives = 51/100 (51%), Gaps = 6/100 (6%)

Query: 7   AREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERD 66
           A+E +   R  +  R+   ++ R  DR R+R     R+      R RD DR  E ++ERD
Sbjct: 34  AKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDRQRETERERD 93

Query: 67  GNRDRNR----DRERERERERDPDRGPRRDTHRDAGPRAG 102
             R+ +R    DRER++++ER+ +R   RD  R+     G
Sbjct: 94  KERETDRHTETDRERQKQKEREMER--VRDREREKQKEMG 131



 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 31/92 (33%), Positives = 54/92 (58%), Gaps = 8/92 (8%)

Query: 11  RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRR-----KRSSDGNRRRDGDRDPERDQER 65
           R R ++++ GR    D  R  DR R+R  +  R     +++ D +R R+ +R  ER+++R
Sbjct: 122 REREKQKEMGRERQTD--RETDRERERQAERERETGRERKTEDRHRERERERKRERERKR 179

Query: 66  DGN-RDRNRDRERERERERDPDRGPRRDTHRD 96
           +   R+R+ D ERER+RE D  R  +R++ R+
Sbjct: 180 ETKERERHTDMERERQRETDRKRDRQRESERE 211



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 34/132 (25%), Positives = 61/132 (46%), Gaps = 24/132 (18%)

Query: 13  RPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGN---- 68
           R R+RD  R    D+ R  ++  DR G+ +R+R  D +R+R+ +R+ ++++E D +    
Sbjct: 46  RDRQRDRERNRERDRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETD 105

Query: 69  --------------RDRNRD------RERERERERDPDRGPRRDTHRDAGPRAGEHGVWE 108
                         RDR R+      RER+ +RE D +R  + +  R+ G          
Sbjct: 106 RERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHR 165

Query: 109 KPRQSRTRDGAR 120
           +  + R R+  R
Sbjct: 166 ERERERKRERER 177



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 31/76 (40%), Positives = 43/76 (56%), Gaps = 10/76 (13%)

Query: 11  RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNR- 69
           R   RER+ GR     + +T DR R+R  + +R+R     +R   +R+   D ER+  R 
Sbjct: 146 RQAERERETGR-----ERKTEDRHRERERERKRERE---RKRETKERERHTDMERERQRE 197

Query: 70  -DRNRDRERERERERD 84
            DR RDR+RE ERERD
Sbjct: 198 TDRKRDRQRESERERD 213



 Score = 36.6 bits (83), Expect = 0.041
 Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 10/83 (12%)

Query: 47  SDGNRRRDGDRDPERDQERDGNRDRNRDRER---------ERERERDPDRGPRRDTHRDA 97
           ++G          +R +ER    DR RDR +         ER+R+RD +R   RD  R+ 
Sbjct: 5   TEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDRER 64

Query: 98  GPRAGEHGVWEKPRQSRTRDGAR 120
             +    G  ++ R+ R RD  R
Sbjct: 65  EKQTDREGERQRERE-RDRDRQR 86



 Score = 30.8 bits (68), Expect = 2.3
 Identities = 36/151 (23%), Positives = 57/151 (37%), Gaps = 26/151 (17%)

Query: 52  RRDGDRDPERDQERDGNRDRNRDRERERERERD---PDRGPRRDTHRDAGPRAGEHGVWE 108
           + +G       +  D  R+R R+ +RER+R ++    DR   RD  RD           E
Sbjct: 4   KTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDRE 63

Query: 109 KPRQSRTRDGARGLTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRR-PESEPPSERYLPST 167
           + +Q+  R+G R                     Q +R+ D  R+R  E E   ER     
Sbjct: 64  REKQT-DREGER---------------------QRERERDRDRQRETERERDKERETDRH 101

Query: 168 PRPGREEVEYYQSEAEGLLECHKCKYLCTGR 198
               RE  +  + E E + +  + K    GR
Sbjct: 102 TETDRERQKQKEREMERVRDREREKQKEMGR 132


>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
           [Homo sapiens]
          Length = 624

 Score = 62.8 bits (151), Expect = 5e-10
 Identities = 41/174 (23%), Positives = 78/174 (44%), Gaps = 8/174 (4%)

Query: 11  RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRD 70
           R + RER+  R    ++G+  DR ++R  D  + +  D  R R+ + + +RD+E++  +D
Sbjct: 395 REKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQD 454

Query: 71  RNRDRERERERERD-------PDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGARGLT 123
           + ++RE++R +E D         R P R  +     R+       +  +S +R      T
Sbjct: 455 KEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKT 514

Query: 124 WDAAAPPGPAPWEAPEPPQPQRK-GDPGRRRPESEPPSERYLPSTPRPGREEVE 176
               +   P+P    +  + + K  D    R E E  +     S  R G+E++E
Sbjct: 515 IKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLE 568



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 25/94 (26%), Positives = 54/94 (57%), Gaps = 5/94 (5%)

Query: 8   REPRARPRERDPGRRPHP-----DQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERD 62
           R+ R+R   RD  +         ++ +  DR ++R  +  R++  +  + +D D++ E+D
Sbjct: 365 RKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKD 424

Query: 63  QERDGNRDRNRDRERERERERDPDRGPRRDTHRD 96
           +E+D  +DR R+RE+E E++RD ++   +D  ++
Sbjct: 425 REKDKEKDREREREKEHEKDRDKEKEKEQDKEKE 458



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 26/111 (23%), Positives = 64/111 (57%), Gaps = 2/111 (1%)

Query: 5   SGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQE 64
           S +R+ R   RE+   +    ++ R  +R R++  +  ++R  + +R ++ ++D E+D+E
Sbjct: 371 SHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKE 430

Query: 65  RDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRT 115
           +D  R+R ++ E++R++E++ ++   ++  +D      E    +K ++SRT
Sbjct: 431 KDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKR--KKDKKSRT 479



 Score = 55.8 bits (133), Expect = 7e-08
 Identities = 26/99 (26%), Positives = 58/99 (58%), Gaps = 13/99 (13%)

Query: 11  RARPRERDPGRRPHPDQGRTHDR--------PRDRPGDPRRK-----RSSDGNRRRDGDR 57
           R+R ++R   + PH  + ++ +R         RD+  D R K     R  + +R ++ +R
Sbjct: 342 RSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKERER 401

Query: 58  DPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRD 96
           + ER++E++  ++++RD+ERE++RE+D ++   R+  ++
Sbjct: 402 EKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKE 440



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 38/122 (31%), Positives = 56/122 (45%), Gaps = 12/122 (9%)

Query: 5   SGAREPRA-RPRERDPGRRPHPDQGRTHDRPRDRPGDP---RRKRSSDGNRRRDGDRDPE 60
           S A EP + +  ER  GR       R+H R + R       RRKRS   +R R  +R   
Sbjct: 290 SAAIEPESGKSNERKGGR------SRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRS 343

Query: 61  RDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGE-HGVWEKPRQ-SRTRDG 118
           R ++R  ++  ++ R + RER +   R   RD  +D   +  E   V EK R+  R R+ 
Sbjct: 344 RQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREK 403

Query: 119 AR 120
            R
Sbjct: 404 ER 405



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 25/107 (23%), Positives = 43/107 (40%), Gaps = 11/107 (10%)

Query: 5   SGAREPRA-----RPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDP 59
           S +R PR      R   R P  R    + +  ++ RD   + R +  S   R+   DRD 
Sbjct: 504 SSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDG 563

Query: 60  ERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGV 106
           +   E      +N    +E+E  ++PD    ++      PR  E+ +
Sbjct: 564 KEKLE------KNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKI 604


>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
           [Homo sapiens]
          Length = 508

 Score = 62.8 bits (151), Expect = 5e-10
 Identities = 41/174 (23%), Positives = 78/174 (44%), Gaps = 8/174 (4%)

Query: 11  RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRD 70
           R + RER+  R    ++G+  DR ++R  D  + +  D  R R+ + + +RD+E++  +D
Sbjct: 279 REKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQD 338

Query: 71  RNRDRERERERERD-------PDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGARGLT 123
           + ++RE++R +E D         R P R  +     R+       +  +S +R      T
Sbjct: 339 KEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKT 398

Query: 124 WDAAAPPGPAPWEAPEPPQPQRK-GDPGRRRPESEPPSERYLPSTPRPGREEVE 176
               +   P+P    +  + + K  D    R E E  +     S  R G+E++E
Sbjct: 399 IKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLE 452



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 25/94 (26%), Positives = 54/94 (57%), Gaps = 5/94 (5%)

Query: 8   REPRARPRERDPGRRPHP-----DQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERD 62
           R+ R+R   RD  +         ++ +  DR ++R  +  R++  +  + +D D++ E+D
Sbjct: 249 RKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKD 308

Query: 63  QERDGNRDRNRDRERERERERDPDRGPRRDTHRD 96
           +E+D  +DR R+RE+E E++RD ++   +D  ++
Sbjct: 309 REKDKEKDREREREKEHEKDRDKEKEKEQDKEKE 342



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 26/111 (23%), Positives = 64/111 (57%), Gaps = 2/111 (1%)

Query: 5   SGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQE 64
           S +R+ R   RE+   +    ++ R  +R R++  +  ++R  + +R ++ ++D E+D+E
Sbjct: 255 SHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKE 314

Query: 65  RDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRT 115
           +D  R+R ++ E++R++E++ ++   ++  +D      E    +K ++SRT
Sbjct: 315 KDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKR--KKDKKSRT 363



 Score = 55.8 bits (133), Expect = 7e-08
 Identities = 26/99 (26%), Positives = 58/99 (58%), Gaps = 13/99 (13%)

Query: 11  RARPRERDPGRRPHPDQGRTHDR--------PRDRPGDPRRK-----RSSDGNRRRDGDR 57
           R+R ++R   + PH  + ++ +R         RD+  D R K     R  + +R ++ +R
Sbjct: 226 RSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKERER 285

Query: 58  DPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRD 96
           + ER++E++  ++++RD+ERE++RE+D ++   R+  ++
Sbjct: 286 EKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKE 324



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 38/122 (31%), Positives = 56/122 (45%), Gaps = 12/122 (9%)

Query: 5   SGAREPRA-RPRERDPGRRPHPDQGRTHDRPRDRPGDP---RRKRSSDGNRRRDGDRDPE 60
           S A EP + +  ER  GR       R+H R + R       RRKRS   +R R  +R   
Sbjct: 174 SAAIEPESGKSNERKGGR------SRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRS 227

Query: 61  RDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGE-HGVWEKPRQ-SRTRDG 118
           R ++R  ++  ++ R + RER +   R   RD  +D   +  E   V EK R+  R R+ 
Sbjct: 228 RQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREK 287

Query: 119 AR 120
            R
Sbjct: 288 ER 289



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 25/107 (23%), Positives = 43/107 (40%), Gaps = 11/107 (10%)

Query: 5   SGAREPRA-----RPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDP 59
           S +R PR      R   R P  R    + +  ++ RD   + R +  S   R+   DRD 
Sbjct: 388 SSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDG 447

Query: 60  ERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGV 106
           +   E      +N    +E+E  ++PD    ++      PR  E+ +
Sbjct: 448 KEKLE------KNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKI 488


>gi|169167715 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 285

 Score = 62.4 bits (150), Expect = 7e-10
 Identities = 44/121 (36%), Positives = 59/121 (48%), Gaps = 15/121 (12%)

Query: 11  RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRD--GDRDPERDQERDGN 68
           R R R+R   R    D+    DR R R  D  R+R  D +R+R+  GDRD E + ER   
Sbjct: 66  RERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETETERQEE 125

Query: 69  RDRNRDRERERERER--------DPDRGPRRDTHRDAGPRAGEHGVW-----EKPRQSRT 115
           R+R RDR+RE++RER        D DR    +  RD     GE   +     E+ +Q  T
Sbjct: 126 RERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQKQRET 185

Query: 116 R 116
           R
Sbjct: 186 R 186



 Score = 59.3 bits (142), Expect = 6e-09
 Identities = 35/95 (36%), Positives = 51/95 (53%), Gaps = 1/95 (1%)

Query: 4   PSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQ 63
           P+  RE R R RER+  R+   ++ R  DR  ++  D +RKR  +  R RD DR  ER  
Sbjct: 54  PAIIRE-RERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWG 112

Query: 64  ERDGNRDRNRDRERERERERDPDRGPRRDTHRDAG 98
           +RD   +  R  ERER+R+R  ++   R   R+ G
Sbjct: 113 DRDRETETERQEERERQRDRKREKDRERQRQREIG 147



 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 36/104 (34%), Positives = 55/104 (52%), Gaps = 1/104 (0%)

Query: 8   REPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDG 67
           +  + R RE+D       D+ R  DR R R  D  RKR   G+R R+ + + + ++ER  
Sbjct: 71  KRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETETERQEERERQR 130

Query: 68  NRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPR 111
           +R R +DRER+R+RE   D+    +T +D   R  E G  E+ R
Sbjct: 131 DRKREKDRERQRQREIGIDKDREIETEKDR-DREREMGETERYR 173



 Score = 55.5 bits (132), Expect = 9e-08
 Identities = 31/86 (36%), Positives = 47/86 (54%), Gaps = 3/86 (3%)

Query: 2   EDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPER 61
           +D    RE     R RD  R     +    DR R+R    R K   + +R R  +R+ +R
Sbjct: 158 KDRDREREMGETERYRDRERERQKQRETRRDRDRERQ---REKEDRERDRDRQKEREKDR 214

Query: 62  DQERDGNRDRNRDRERERERERDPDR 87
            +ER+  RDR+++R+RER+RE+D DR
Sbjct: 215 YRERETGRDRDKERDRERQREKDRDR 240



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 30/108 (27%), Positives = 59/108 (54%), Gaps = 1/108 (0%)

Query: 15  RERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERD-GNRDRNR 73
           R+R+       ++ R  DR R++  + +R+R    ++ R+ + + +RD+ER+ G  +R R
Sbjct: 114 RDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYR 173

Query: 74  DRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGARG 121
           DRERER+++R+  R   R+  R+   R  +    ++  + R R+   G
Sbjct: 174 DRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETG 221



 Score = 52.8 bits (125), Expect = 6e-07
 Identities = 34/98 (34%), Positives = 51/98 (52%), Gaps = 7/98 (7%)

Query: 13  RPRERDPGRRP-HPDQGRTHDRPRDRPGDPRRKRSSDG-NRRRDGDRDPERDQERDGNRD 70
           R RER+ G    + D+ R   + R+   D  R+R  +  +R RD DR  ER+++R   R+
Sbjct: 160 RDREREMGETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERE 219

Query: 71  RNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWE 108
             RDR++ER+RER  ++   R    D  P     G WE
Sbjct: 220 TGRDRDKERDRERQREKDRDRQKAIDCVP-----GRWE 252



 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 43/139 (30%), Positives = 59/139 (42%), Gaps = 15/139 (10%)

Query: 11  RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSS-------DGNRRRDGDRDPERDQ 63
           R R RE+D  R+   + G   DR  +   D  R+R         D  R R   R+  RD+
Sbjct: 130 RDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQKQRETRRDR 189

Query: 64  ERDGNR---DRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120
           +R+  R   DR RDR+R++ERE+  DR   R+T RD           EK R  +      
Sbjct: 190 DRERQREKEDRERDRDRQKEREK--DRYRERETGRDRDKERDRERQREKDRDRQKAIDCV 247

Query: 121 GLTWDA---AAPPGPAPWE 136
              W+    A    P  WE
Sbjct: 248 PGRWEVTVMAVDCVPGRWE 266



 Score = 32.3 bits (72), Expect = 0.78
 Identities = 23/80 (28%), Positives = 35/80 (43%), Gaps = 26/80 (32%)

Query: 8   REPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDG 67
           +E R R R+R                        +++R  D  R R+  RD  RD+ERD 
Sbjct: 197 KEDRERDRDR------------------------QKEREKDRYRERETGRD--RDKERDR 230

Query: 68  NRDRNRDRERERERERDPDR 87
            R R +DR+R++  +  P R
Sbjct: 231 ERQREKDRDRQKAIDCVPGR 250



 Score = 30.0 bits (66), Expect = 3.9
 Identities = 19/59 (32%), Positives = 27/59 (45%), Gaps = 4/59 (6%)

Query: 3   DPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPER 61
           D    R+     RERD  R+      R  DR R+R     R +  D  R+R+ DRD ++
Sbjct: 188 DRDRERQREKEDRERDRDRQKE----REKDRYRERETGRDRDKERDRERQREKDRDRQK 242


>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
           sapiens]
          Length = 1031

 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 40/123 (32%), Positives = 55/123 (44%), Gaps = 5/123 (4%)

Query: 6   GAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRD--GDRDPERDQ 63
           G      R R    GR     + R+    R + GD RR RS D +RRR+    RD  R +
Sbjct: 2   GRESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSR 61

Query: 64  ERDG---NRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120
            RD     R R+R+R+R RER R   R  RR   R  G R+       K +++  R  ++
Sbjct: 62  SRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSK 121

Query: 121 GLT 123
             T
Sbjct: 122 EKT 124



 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 42/148 (28%), Positives = 62/148 (41%), Gaps = 21/148 (14%)

Query: 15  RERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDRNRD 74
           RE    R+    +GR+  R R R    +R +  D  R R  DRD  R++ R  ++ R+R 
Sbjct: 3   RESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRS 62

Query: 75  RERE-----RERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGARGLTWDAAAP 129
           R+R+     R RERD  R  RR   RD              R+SR+R   R      ++ 
Sbjct: 63  RDRKRLRRSRSRERDRSRERRRSRSRDR-------------RRSRSRSRGRR---SRSSS 106

Query: 130 PGPAPWEAPEPPQPQRKGDPGRRRPESE 157
           PG    +     + + K D G    E +
Sbjct: 107 PGNKSKKTENRSRSKEKTDGGESSKEKK 134



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 35/179 (19%), Positives = 73/179 (40%), Gaps = 17/179 (9%)

Query: 11  RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDG--- 67
           R+R RERD  R     + R   R R R    R + SS GN+ +  +      ++ DG   
Sbjct: 70  RSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGGES 129

Query: 68  NRDRNRDR-ERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGARGLTWDA 126
           ++++ +D+ ++E E+E+D     +     +   R      W + ++ +  +    L  + 
Sbjct: 130 SKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKKAMENIGELKKEI 189

Query: 127 AAPPGPAPW-------EAPEPPQPQRKGDPGRRRPESEPPSERYLPSTPRPGREEVEYY 178
                   W       +  +P + +++G+      E   P + Y+       +EEV+ +
Sbjct: 190 EEMKQGKKWSLEDDDDDEDDPAEAEKEGN--EMEGEELDPLDAYMEEV----KEEVKKF 242



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 31/102 (30%), Positives = 46/102 (45%), Gaps = 15/102 (14%)

Query: 11  RARPRERDPGRRPHPDQGR---THDRPRDRPGDPRRKRSSDGNRRRDGDR-------DPE 60
           R R R RD  R    D+ R   +  R RDR  + RR RS D  R R   R        P 
Sbjct: 49  RERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPG 108

Query: 61  RDQERDGNRDRNRDR----ERERERERDPDRGPRRDTHRDAG 98
              ++  NR R++++    E  +E+++D D     +  +DAG
Sbjct: 109 NKSKKTENRSRSKEKTDGGESSKEKKKDKD-DKEDEKEKDAG 149


>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
            theta, 150/170kDa [Homo sapiens]
          Length = 1382

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 56/171 (32%), Positives = 67/171 (39%), Gaps = 17/171 (9%)

Query: 8    REPRARPRERDPG-RRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRR--DGDRDPERDQE 64
            R PR R  + D G RR   D  R+  R  D    PRR    D   RR  D DR P R  +
Sbjct: 1036 RGPR-RGMDDDRGPRRGGADDERSSWRNADDDRGPRRGLDDDRGPRRGMDDDRGPRRGMD 1094

Query: 65   RDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAG---EHGVW---EKPRQSRTRDG 118
             D    R  D +R   R  D DRGP R+   D  PR G   + G W   +  R SR  D 
Sbjct: 1095 DDRGPRRGMDDDRGPRRGLDDDRGPWRNADDDRIPRRGAEDDRGPWRNMDDDRLSRRADD 1154

Query: 119  ARGLTWDAAAPPG-------PAPWEAPEPPQPQRKGDPGRRRPESEPPSER 162
             R       + PG       P  W   E  + +  G P   RP  E   +R
Sbjct: 1155 DRFPRRGDDSRPGPWRPLVKPGGWREKEKAREESWGPPRESRPSEEREWDR 1205



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 55/183 (30%), Positives = 68/183 (37%), Gaps = 17/183 (9%)

Query: 10   PRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGN---RRRDGDRDPERDQERD 66
            P  R  + D G     D+ R   R  D    PRR  + D     R  D DR P R  + D
Sbjct: 1017 PPRRGLDEDRGSWRTADEDRGPRRGMDDDRGPRRGGADDERSSWRNADDDRGPRRGLDDD 1076

Query: 67   GNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAG---EHGVWEKPRQSRTRDGARGLT 123
                R  D +R   R  D DRGPRR    D GPR G   + G W      R     RG  
Sbjct: 1077 RGPRRGMDDDRGPRRGMDDDRGPRRGMDDDRGPRRGLDDDRGPWRNADDDRI--PRRG-- 1132

Query: 124  WDAAAPPGPAPWEAPEPPQPQRKGDPGR--RRPESEPPSERYLPSTPRPGREEVEYYQSE 181
                A     PW   +  +  R+ D  R  RR +   P   + P     G  E E  + E
Sbjct: 1133 ----AEDDRGPWRNMDDDRLSRRADDDRFPRRGDDSRPGP-WRPLVKPGGWREKEKAREE 1187

Query: 182  AEG 184
            + G
Sbjct: 1188 SWG 1190



 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 42/120 (35%), Positives = 54/120 (45%), Gaps = 16/120 (13%)

Query: 14   PRERDPGR----RPHPDQGRTHDRPRDRP---GDPRRKRSSDGNRRRDGDRDPERDQERD 66
            PR  D  R    RP    G   ++ + R    G PR  R S+    R+ DR+ ERD++  
Sbjct: 1158 PRRGDDSRPGPWRPLVKPGGWREKEKAREESWGPPRESRPSE---EREWDREKERDRDNQ 1214

Query: 67   GNRDRNRDRERERERERDPDRGPRRDTHRDAG----PRAGEHGVW--EKPRQSRTRDGAR 120
               + ++D ERER+RERD DR  R    RD G      A E   W     R  R RD  R
Sbjct: 1215 DREENDKDPERERDRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRR 1274



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 51/165 (30%), Positives = 60/165 (36%), Gaps = 17/165 (10%)

Query: 4    PSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRP---GD-----PRRKRSSDGNRRR-- 53
            P    E R  P E++  R    D+ R+H R  +RP   GD     P  +   D   RR  
Sbjct: 903  PEADSEWRRGPPEKEWRRGEGRDEDRSHRRDEERPRRLGDDEDREPSLRPDDDRVPRRGM 962

Query: 54   DGDRDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAG-------PRAGEHGV 106
            D DR P R  E D    R  D +R   R  D DR PRR    D G        R    G+
Sbjct: 963  DDDRGPRRGPEEDRFSRRGADDDRPSWRNTDDDRPPRRIADEDRGNWRHADDDRPPRRGL 1022

Query: 107  WEKPRQSRTRDGARGLTWDAAAPPGPAPWEAPEPPQPQRKGDPGR 151
             E     RT D  RG         GP    A +     R  D  R
Sbjct: 1023 DEDRGSWRTADEDRGPRRGMDDDRGPRRGGADDERSSWRNADDDR 1067



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 51/146 (34%), Positives = 65/146 (44%), Gaps = 29/146 (19%)

Query: 2    EDPSGAREPRARPR------ERDPGRRPHPDQ----GRTHDR-PRDRPGDPR-RKRSSDG 49
            ED S  R+   RPR      +R+P  RP  D+    G   DR PR  P + R  +R +D 
Sbjct: 926  EDRSHRRDEE-RPRRLGDDEDREPSLRPDDDRVPRRGMDDDRGPRRGPEEDRFSRRGADD 984

Query: 50   NR----RRDGDRDPER--DQERDGNRDRNRDR--------ERERERERDPDRGPRRDTHR 95
            +R      D DR P R  D++R   R  + DR        +R   R  D DRGPRR    
Sbjct: 985  DRPSWRNTDDDRPPRRIADEDRGNWRHADDDRPPRRGLDEDRGSWRTADEDRGPRRGMDD 1044

Query: 96   DAGPRAGEHGVWEKPRQSRTRDGARG 121
            D GPR G  G  ++    R  D  RG
Sbjct: 1045 DRGPRRG--GADDERSSWRNADDDRG 1068



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 53/196 (27%), Positives = 70/196 (35%), Gaps = 36/196 (18%)

Query: 4    PSGAREP-RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERD 62
            P G RE  +AR     P R   P + R  DR ++R  D + +  +D +  R+ DR+ + D
Sbjct: 1175 PGGWREKEKAREESWGPPRESRPSEEREWDREKERDRDNQDREENDKDPERERDRERDVD 1234

Query: 63   QERDGNRDRN---------------RDRERERERERDPDRGPRRDTHRDAGPRAGEHGVW 107
            +E    R R+               RD  R  +R+RD DR   RD  RD   R       
Sbjct: 1235 REDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRD-DRRRERDDRRDLRER------- 1286

Query: 108  EKPRQSRTRDGARGLTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSERYLPST 167
               R  R R G             P   E  E    +R  D    R E   P  R  P  
Sbjct: 1287 RDLRDDRDRRGP------------PLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPA 1334

Query: 168  PRPGREEVEYYQSEAE 183
                RE     + E E
Sbjct: 1335 LSRDRERDRDREREGE 1350



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 47/154 (30%), Positives = 66/154 (42%), Gaps = 17/154 (11%)

Query: 8    REPRARPRERDPGRRPHPDQGRTHDRPRDRPG---DPRRKRSS--DGNRRRDGDRDPERD 62
            RE   +  ER+  R    D+     RPRD  G    P  + SS  D +RR D DRD +R 
Sbjct: 1216 REENDKDPERERDRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRD-DRR 1274

Query: 63   QERDGNRD--RNRDRERERERERDPDRGPRRD--THRDAGPRAGEHGVWEK------PRQ 112
            +ERD  RD    RD   +R+R   P R  R +  + R A  R  +  V E+      P  
Sbjct: 1275 RERDDRRDLRERRDLRDDRDRRGPPLRSEREEVSSWRRADDRKDDR-VEERDPPRRVPPP 1333

Query: 113  SRTRDGARGLTWDAAAPPGPAPWEAPEPPQPQRK 146
            + +RD  R    +       A W A +  +  R+
Sbjct: 1334 ALSRDRERDRDREREGEKEKASWRAEKDRESLRR 1367



 Score = 31.2 bits (69), Expect = 1.7
 Identities = 31/122 (25%), Positives = 47/122 (38%), Gaps = 27/122 (22%)

Query: 56  DRDPERDQER---DGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQ 112
           +R+  R++ER   D +  R   R  +R+ E    +GP  D+    GP   E   W   R+
Sbjct: 867 ERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKE---W---RR 920

Query: 113 SRTRDGARGLTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSERYLPSTPRPGR 172
              RD  R                  +  +P+R GD   R P   P  +R     PR G 
Sbjct: 921 GEGRDEDRS--------------HRRDEERPRRLGDDEDREPSLRPDDDR----VPRRGM 962

Query: 173 EE 174
           ++
Sbjct: 963 DD 964


>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapiens]
          Length = 1341

 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 37/98 (37%), Positives = 57/98 (58%), Gaps = 13/98 (13%)

Query: 9    EPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDG----DRDPERDQE 64
            E   R +ER+  R+   +Q     + R++  +  R R  +  +RR+     DR+ ER++E
Sbjct: 1240 ERAERAKEREKRRK---EQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERE 1296

Query: 65   RD-GNRDRNRDRERERERERDPDRGPRRDTHRDAGPRA 101
            RD G+RDR+R+R+RER RERD     RRDT R +  R+
Sbjct: 1297 RDRGDRDRDRERDRERGRERD-----RRDTKRHSRSRS 1329



 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 34/93 (36%), Positives = 45/93 (48%), Gaps = 8/93 (8%)

Query: 2    EDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPER 61
            E     ++ R +  ER+  R+   ++ R H R RDR  +  R+R      R D DRD ER
Sbjct: 1254 EQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERD-----RGDRDRDRER 1308

Query: 62   DQERDGNRDRNRDRERERERERDP---DRGPRR 91
            D+ER   RDR   +   R R R     DRG RR
Sbjct: 1309 DRERGRERDRRDTKRHSRSRSRSTPVRDRGGRR 1341



 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 33/86 (38%), Positives = 48/86 (55%), Gaps = 5/86 (5%)

Query: 35   RDRPGDPRRKRSSDGN---RRRDGDRDPERDQERDGNRDRNRDRERERERERDPDRGPR- 90
            R +  + RRK   +     R ++ +R+  R  ER+  R+ +R+R+RERERER+ DRG R 
Sbjct: 1244 RAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDRGDRD 1303

Query: 91   RDTHRDAGPRAGEHGVWEKPRQSRTR 116
            RD  RD   R  E    +  R SR+R
Sbjct: 1304 RDRERDR-ERGRERDRRDTKRHSRSR 1328



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 31/96 (32%), Positives = 51/96 (53%), Gaps = 2/96 (2%)

Query: 7    AREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPER-DQER 65
            A+E   R +E++   +   ++    +R R    + RR+ S + +R R+ +R+ +R D++R
Sbjct: 1245 AKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDRGDRDR 1304

Query: 66   DGNRDRNRDRERERERERDPDRGPRRDTH-RDAGPR 100
            D  RDR R RER+R   +   R   R T  RD G R
Sbjct: 1305 DRERDRERGRERDRRDTKRHSRSRSRSTPVRDRGGR 1340



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 41/168 (24%), Positives = 58/168 (34%), Gaps = 19/168 (11%)

Query: 5   SGAREPRARPRERDP---GRRPHPD---------QGRTHDRPRDRPGDPRRKRSSDGNRR 52
           S +    +R R R P   G R H           Q RTH  PR RP    R  S   +R 
Sbjct: 582 SSSSSSSSRSRSRSPDSSGSRSHSPLRSKQRDVAQARTHANPRGRPKMGSRSTSESRSRS 641

Query: 53  RDGDRDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQ 112
           R   R    +  +  +   +RD        +DP  G        A P   +  V E   +
Sbjct: 642 RSRSRSASSNSRKSLSPGVSRDSSTSYTETKDPSSG-----QEVATPPVPQLQVCEP--K 694

Query: 113 SRTRDGARGLTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPS 160
            RT   +  +     + P  A     +  QP+R         E+EPP+
Sbjct: 695 ERTSTSSSSVQARRLSQPESAEKHVTQRLQPERGSPKKCEAEEAEPPA 742



 Score = 36.2 bits (82), Expect = 0.054
 Identities = 28/101 (27%), Positives = 43/101 (42%), Gaps = 9/101 (8%)

Query: 9    EPRARPRERDPGRRPHPDQGRTHDRPRDRPGD-------PRRKRSSDGNRRRDGDRDPER 61
            E +  PR   P   P P Q   H R   R  +         R+R  +   R   +R+ +R
Sbjct: 1109 EEQGIPRPLHPPPPP-PVQPPQHPRAEQREQERAVREQWAEREREMERRERTRSEREWDR 1167

Query: 62   DQERDGNRDRNRDRERER-ERERDPDRGPRRDTHRDAGPRA 101
            D+ R+G R R+R R+R R ER +  ++   +       P A
Sbjct: 1168 DKVREGPRSRSRSRDRRRKERAKSKEKKSEKKEKAQEEPPA 1208



 Score = 29.6 bits (65), Expect = 5.1
 Identities = 19/64 (29%), Positives = 29/64 (45%), Gaps = 3/64 (4%)

Query: 60   ERDQERDGNR---DRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTR 116
            ER +ER+  R   +    +ERE+E ER+ +R   R+  R+           E+ R    R
Sbjct: 1243 ERAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDRGDR 1302

Query: 117  DGAR 120
            D  R
Sbjct: 1303 DRDR 1306


>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
           containing B [Homo sapiens]
          Length = 546

 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 37/120 (30%), Positives = 56/120 (46%), Gaps = 10/120 (8%)

Query: 11  RARPRERDPGRRPHPDQGRTHDRPRDRPG-DPRRKRSSDGNRRRDGDRDPERDQERDGNR 69
           R   R R   R  H  + R+ DR  DR   D  R++ ++  RRRD D D ER  ER+  R
Sbjct: 323 RGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKER 382

Query: 70  DRNRDRER---------ERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120
           +R+R+R +         E++ + D D    RD  RD+           + R+ R+R  +R
Sbjct: 383 ERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSR 442



 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 34/140 (24%), Positives = 61/140 (43%), Gaps = 21/140 (15%)

Query: 5   SGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRR----------- 53
           S +R+ +   R+RD  R    ++GR  DR  D+     R++  + +R R           
Sbjct: 340 SRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVE 399

Query: 54  ------DGDRDPERDQERDGNRDRNRDRERERERE---RDPDRGPRRDTHRDAGPRAGEH 104
                 D D    RD +RD  +++   R R RER+   R   R   + +   +  ++ +H
Sbjct: 400 EKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKH 459

Query: 105 GVWEKPRQS-RTRDGARGLT 123
               K + + R+R G++G T
Sbjct: 460 KNESKEKSNKRSRSGSQGRT 479



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 34/112 (30%), Positives = 46/112 (41%), Gaps = 2/112 (1%)

Query: 8   REPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDG 67
           R  R+  R   P R P   + R+H R         R+   +  R+R      ER++ER  
Sbjct: 258 RRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKERRR 317

Query: 68  NR--DRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRD 117
           +R  DR  +R R R RER   R   RD   D   R  E     +  + R RD
Sbjct: 318 SRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRD 369



 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 36/123 (29%), Positives = 51/123 (41%), Gaps = 13/123 (10%)

Query: 11  RARPRE-RDPGRRPHPDQGRTHDRPRDRPG--------DPRRKRSSDGNRRRDG----DR 57
           + RPR+ +  G+    +  R  +R R R           PRR RS   +R   G    DR
Sbjct: 234 KTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDR 293

Query: 58  DPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRD 117
           + ER++ER       ++RE+ER R R  DRG  R   R            ++    R RD
Sbjct: 294 ELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRD 353

Query: 118 GAR 120
             R
Sbjct: 354 RER 356



 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 21/88 (23%), Positives = 41/88 (46%)

Query: 5   SGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQE 64
           S  R+ R+R R R+ G+R          + ++   +   KRS  G++ R    +  + +E
Sbjct: 430 SRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKRE 489

Query: 65  RDGNRDRNRDRERERERERDPDRGPRRD 92
              +++++R R R +ER    D    +D
Sbjct: 490 HSPSKEKSRKRSRSKERSHKRDHSDSKD 517



 Score = 31.2 bits (69), Expect = 1.7
 Identities = 21/99 (21%), Positives = 39/99 (39%), Gaps = 11/99 (11%)

Query: 8   REPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRR-----------DGD 56
           +E +   R RD  R    ++  +  R R+R    R +  + G R R           +  
Sbjct: 404 KEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNES 463

Query: 57  RDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHR 95
           ++    + R G++ R    E+ ++RE  P +   R   R
Sbjct: 464 KEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSR 502



 Score = 28.9 bits (63), Expect = 8.6
 Identities = 13/60 (21%), Positives = 28/60 (46%)

Query: 11  RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRD 70
           +++ RE  P +     + R+ +R   R     + +S   +RRR    + E  +++  N+D
Sbjct: 484 KSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQHKNKD 543


>gi|213385278 TNF receptor-associated factor 3 interacting protein 1
           isoform 2 [Homo sapiens]
          Length = 625

 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 40/133 (30%), Positives = 66/133 (49%), Gaps = 33/133 (24%)

Query: 6   GAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRD------- 58
           G  E + R   RD   R   ++ +   +PR++  D  + + + GNR R+G+R+       
Sbjct: 169 GDAEIKERSTSRD---RKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARAR 225

Query: 59  PERDQERD-GNRDRNRDRE------------------RERERERDPDRGPRRDTHRDAGP 99
           P+ ++++D GNR+R+RD E                  R+R+RERD D+G  RD  R    
Sbjct: 226 PDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRR---V 282

Query: 100 RAGEHGVWEKPRQ 112
           + GEH  W+  R+
Sbjct: 283 KNGEHS-WDLDRE 294



 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 61/212 (28%), Positives = 87/212 (41%), Gaps = 39/212 (18%)

Query: 6   GAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQER 65
           G RE RA+ R R    R      R  DR  +R  +  RK      + R  DRD ERD+++
Sbjct: 215 GERE-RAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDK 273

Query: 66  DGNRDRNR--------DRERERERERDPD-------------------RGPRRDTHRDAG 98
             +RDR R        D +RE+ RE D                     +  + +T  +  
Sbjct: 274 GKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETETEIS 333

Query: 99  PRAGEHGVWEKPRQSRTRDGARG-LTWDAAAPPGPA---PWEAPEPPQ-PQRKGDPGRRR 153
            RA +  +  K  + R+++   G  T DA    GPA     E PE P+ P       RR 
Sbjct: 334 TRASK-SLTTKTSKRRSKNSVEGDSTSDAEGDAGPAGQDKSEVPETPEIPNELSSNIRRI 392

Query: 154 PESEPPSERYLPSTPRPGREE-VEYYQSEAEG 184
           P   P S R  P+ PR  R++ +E  Q +  G
Sbjct: 393 P--RPGSAR--PAPPRVKRQDSMEALQMDRSG 420



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 49/189 (25%), Positives = 78/189 (41%), Gaps = 27/189 (14%)

Query: 12  ARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGD-------RDPERDQE 64
           +R +E D  +    ++ R H    DR     ++RS+  +R++  +       R+ ++D+E
Sbjct: 144 SRSQELD-NKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKE 202

Query: 65  RDGNRDRNRDRERERER---------ERDPDRGPR---RDTHRDAGPRAGEHGVWEKPR- 111
           +      NR RE ERER         ER  DRG R   RD+ R         G  EK R 
Sbjct: 203 KAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERL 262

Query: 112 --QSRTRDGARGLTWD-AAAPPGPAPWEAPEPPQPQRKGD-PGRRRPESEPPSERYLPST 167
             + R RD  +G   D      G   W+     +  R+ D P ++   S   S++    T
Sbjct: 263 RDRDRERDRDKGKDRDRRRVKNGEHSWDLDR--EKNREHDKPEKKSASSGEMSKKLSDGT 320

Query: 168 PRPGREEVE 176
            +  + E E
Sbjct: 321 FKDSKAETE 329


>gi|20070262 TNF receptor-associated factor 3 interacting protein 1
           isoform 1 [Homo sapiens]
          Length = 691

 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 40/133 (30%), Positives = 66/133 (49%), Gaps = 33/133 (24%)

Query: 6   GAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRD------- 58
           G  E + R   RD   R   ++ +   +PR++  D  + + + GNR R+G+R+       
Sbjct: 169 GDAEIKERSTSRD---RKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARAR 225

Query: 59  PERDQERD-GNRDRNRDRE------------------RERERERDPDRGPRRDTHRDAGP 99
           P+ ++++D GNR+R+RD E                  R+R+RERD D+G  RD  R    
Sbjct: 226 PDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRR---V 282

Query: 100 RAGEHGVWEKPRQ 112
           + GEH  W+  R+
Sbjct: 283 KNGEHS-WDLDRE 294



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 30/98 (30%), Positives = 43/98 (43%), Gaps = 1/98 (1%)

Query: 6   GAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQER 65
           G RE RA+ R R    R      R  DR  +R  +  RK      + R  DRD ERD+++
Sbjct: 215 GERE-RAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDK 273

Query: 66  DGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGE 103
             +RDR R +  E   + D ++    D        +GE
Sbjct: 274 GKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGE 311



 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 33/95 (34%), Positives = 50/95 (52%), Gaps = 10/95 (10%)

Query: 5   SGAREPRARPRERDPGRRPHPDQGRTHDRP-RDRPGDPRRKRSSDGNRRRDGDRDPER-- 61
           +G    R   RER   R   PD  R  DR  R+R  D  RK+ ++  R+ +G ++ ER  
Sbjct: 207 NGGNRHREGERERAKARA-RPDNERQKDRGNRERDRDSERKKETE--RKSEGGKEKERLR 263

Query: 62  DQERDGNRDRNRDRERER----ERERDPDRGPRRD 92
           D++R+ +RD+ +DR+R R    E   D DR   R+
Sbjct: 264 DRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNRE 298



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 49/189 (25%), Positives = 78/189 (41%), Gaps = 27/189 (14%)

Query: 12  ARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGD-------RDPERDQE 64
           +R +E D  +    ++ R H    DR     ++RS+  +R++  +       R+ ++D+E
Sbjct: 144 SRSQELD-NKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKE 202

Query: 65  RDGNRDRNRDRERERER---------ERDPDRGPR---RDTHRDAGPRAGEHGVWEKPR- 111
           +      NR RE ERER         ER  DRG R   RD+ R         G  EK R 
Sbjct: 203 KAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERL 262

Query: 112 --QSRTRDGARGLTWD-AAAPPGPAPWEAPEPPQPQRKGD-PGRRRPESEPPSERYLPST 167
             + R RD  +G   D      G   W+     +  R+ D P ++   S   S++    T
Sbjct: 263 RDRDRERDRDKGKDRDRRRVKNGEHSWDLDR--EKNREHDKPEKKSASSGEMSKKLSDGT 320

Query: 168 PRPGREEVE 176
            +  + E E
Sbjct: 321 FKDSKAETE 329



 Score = 32.0 bits (71), Expect = 1.0
 Identities = 21/83 (25%), Positives = 35/83 (42%), Gaps = 14/83 (16%)

Query: 2   EDPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPER 61
           +D       R   R+++  R+    + +   R RDR               RD D+  +R
Sbjct: 232 KDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRE--------------RDRDKGKDR 277

Query: 62  DQERDGNRDRNRDRERERERERD 84
           D+ R  N + + D +RE+ RE D
Sbjct: 278 DRRRVKNGEHSWDLDREKNREHD 300


>gi|125988409 RED protein [Homo sapiens]
          Length = 557

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 40/150 (26%), Positives = 70/150 (46%), Gaps = 11/150 (7%)

Query: 6   GAREPRARPRER---DPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERD 62
           G R  + + +++   +  + P  D     D     P   +  R  +  R R+ +RD ERD
Sbjct: 292 GTRNKKLKKKDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERDRERD 351

Query: 63  QERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGARGL 122
           ++RD  R+R RDRERERER+R+ +   +R ++ +  P+  +  +        T++  + +
Sbjct: 352 RDRDRERERERDRERERERDREREEEKKRHSYFEK-PKVDDEPMDVDKGPGSTKELIKSI 410

Query: 123 TWDAAAPPGPAPWEAPE----PPQPQRKGD 148
               A   G A WE  E    P   ++ GD
Sbjct: 411 NEKFA---GSAGWEGTESLKKPEDKKQLGD 437



 Score = 45.4 bits (106), Expect = 9e-05
 Identities = 30/80 (37%), Positives = 38/80 (47%), Gaps = 26/80 (32%)

Query: 4   PSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQ 63
           PS  + PR + RER                         R+R  D  R RD DR  ER++
Sbjct: 327 PSTTKTPRDKERER------------------------YRERERDRERDRDRDR--ERER 360

Query: 64  ERDGNRDRNRDRERERERER 83
           ERD  R+R RDRERE E++R
Sbjct: 361 ERDRERERERDREREEEKKR 380



 Score = 32.7 bits (73), Expect = 0.60
 Identities = 30/107 (28%), Positives = 46/107 (42%), Gaps = 8/107 (7%)

Query: 10  PRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNR 69
           PRA P    P +  H +  R ++   D P   RRK+ S   + R  + + ER+      +
Sbjct: 43  PRAAPTSAPPSKSRHHEMPREYNEDED-PAARRRKKKSYYAKLRQQEIEREREL---AEK 98

Query: 70  DRNRDRERERERERDPDRGPRRDT---HRDAGPRA-GEHGVWEKPRQ 112
            R+R +ER     +D +      T   +R  GP A  +    EK RQ
Sbjct: 99  YRDRAKERRDGVNKDYEETELISTTANYRAVGPTAEADKSAAEKRRQ 145


>gi|201023341 FIP1 like 1 isoform 3 [Homo sapiens]
          Length = 520

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 31/71 (43%), Positives = 43/71 (60%), Gaps = 6/71 (8%)

Query: 52  RRDGDRDPERDQERDGNRDRNRDRERERERERDPDRGP-----RRDTHRDAGPRAGEHGV 106
           RR+ DRD ERD++R+ +RDR+R+RER RERER+ D  P       D  R       E G 
Sbjct: 382 RREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERG- 440

Query: 107 WEKPRQSRTRD 117
           +E+ R SR ++
Sbjct: 441 YERHRASREKE 451



 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 25/71 (35%), Positives = 39/71 (54%), Gaps = 3/71 (4%)

Query: 50  NRRRDGDRDPERDQERDGNRDRNRDRERERERERDP---DRGPRRDTHRDAGPRAGEHGV 106
           +R R+ DRD ERD++RD  R+R R+RERER+    P   +    R  +R+   R  E   
Sbjct: 386 DRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHR 445

Query: 107 WEKPRQSRTRD 117
             + ++ R R+
Sbjct: 446 ASREKEERHRE 456



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 34/105 (32%), Positives = 45/105 (42%), Gaps = 11/105 (10%)

Query: 26  DQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDR-------NRDRERE 78
           D  +  D    R  D  R+R  D  R RD DR+ ER +ER+  RD        N D ER 
Sbjct: 372 DTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERY 431

Query: 79  RERERDPDRG---PRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120
           R RE   +RG    R    ++   R   H   E+ R   +R  +R
Sbjct: 432 RYREY-AERGYERHRASREKEERHRERRHREKEETRHKSSRSNSR 475



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 38/139 (27%), Positives = 62/139 (44%), Gaps = 23/139 (16%)

Query: 7   AREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKR---------SSDGNR---RRD 54
           AR  + R RERD  R    ++ R  DR R+R  +  R+R         +SD  R   R  
Sbjct: 381 ARREKDRDRERDRDR----ERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREY 436

Query: 55  GDRDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGE-HGVWEKPRQS 113
            +R  ER +      +R+R+R R RE+E    +  R ++ R      G+ H   +  +  
Sbjct: 437 AERGYERHRASREKEERHRER-RHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSK 495

Query: 114 RTRDGARGLTWDAAAPPGP 132
           R+++G      +A + P P
Sbjct: 496 RSKEGK-----EAGSEPAP 509


>gi|201023339 FIP1 like 1 isoform 2 [Homo sapiens]
          Length = 588

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 31/71 (43%), Positives = 43/71 (60%), Gaps = 6/71 (8%)

Query: 52  RRDGDRDPERDQERDGNRDRNRDRERERERERDPDRGP-----RRDTHRDAGPRAGEHGV 106
           RR+ DRD ERD++R+ +RDR+R+RER RERER+ D  P       D  R       E G 
Sbjct: 450 RREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERG- 508

Query: 107 WEKPRQSRTRD 117
           +E+ R SR ++
Sbjct: 509 YERHRASREKE 519



 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 25/71 (35%), Positives = 39/71 (54%), Gaps = 3/71 (4%)

Query: 50  NRRRDGDRDPERDQERDGNRDRNRDRERERERERDP---DRGPRRDTHRDAGPRAGEHGV 106
           +R R+ DRD ERD++RD  R+R R+RERER+    P   +    R  +R+   R  E   
Sbjct: 454 DRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHR 513

Query: 107 WEKPRQSRTRD 117
             + ++ R R+
Sbjct: 514 ASREKEERHRE 524



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 34/105 (32%), Positives = 45/105 (42%), Gaps = 11/105 (10%)

Query: 26  DQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDR-------NRDRERE 78
           D  +  D    R  D  R+R  D  R RD DR+ ER +ER+  RD        N D ER 
Sbjct: 440 DTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERY 499

Query: 79  RERERDPDRG---PRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120
           R RE   +RG    R    ++   R   H   E+ R   +R  +R
Sbjct: 500 RYREY-AERGYERHRASREKEERHRERRHREKEETRHKSSRSNSR 543



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 38/139 (27%), Positives = 62/139 (44%), Gaps = 23/139 (16%)

Query: 7   AREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKR---------SSDGNR---RRD 54
           AR  + R RERD  R    ++ R  DR R+R  +  R+R         +SD  R   R  
Sbjct: 449 ARREKDRDRERDRDR----ERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREY 504

Query: 55  GDRDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGE-HGVWEKPRQS 113
            +R  ER +      +R+R+R R RE+E    +  R ++ R      G+ H   +  +  
Sbjct: 505 AERGYERHRASREKEERHRER-RHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSK 563

Query: 114 RTRDGARGLTWDAAAPPGP 132
           R+++G      +A + P P
Sbjct: 564 RSKEGK-----EAGSEPAP 577


>gi|40254978 FIP1 like 1 isoform 1 [Homo sapiens]
          Length = 594

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 31/71 (43%), Positives = 43/71 (60%), Gaps = 6/71 (8%)

Query: 52  RRDGDRDPERDQERDGNRDRNRDRERERERERDPDRGP-----RRDTHRDAGPRAGEHGV 106
           RR+ DRD ERD++R+ +RDR+R+RER RERER+ D  P       D  R       E G 
Sbjct: 456 RREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERG- 514

Query: 107 WEKPRQSRTRD 117
           +E+ R SR ++
Sbjct: 515 YERHRASREKE 525



 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 25/71 (35%), Positives = 39/71 (54%), Gaps = 3/71 (4%)

Query: 50  NRRRDGDRDPERDQERDGNRDRNRDRERERERERDP---DRGPRRDTHRDAGPRAGEHGV 106
           +R R+ DRD ERD++RD  R+R R+RERER+    P   +    R  +R+   R  E   
Sbjct: 460 DRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHR 519

Query: 107 WEKPRQSRTRD 117
             + ++ R R+
Sbjct: 520 ASREKEERHRE 530



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 34/105 (32%), Positives = 45/105 (42%), Gaps = 11/105 (10%)

Query: 26  DQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDR-------NRDRERE 78
           D  +  D    R  D  R+R  D  R RD DR+ ER +ER+  RD        N D ER 
Sbjct: 446 DTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERY 505

Query: 79  RERERDPDRG---PRRDTHRDAGPRAGEHGVWEKPRQSRTRDGAR 120
           R RE   +RG    R    ++   R   H   E+ R   +R  +R
Sbjct: 506 RYREY-AERGYERHRASREKEERHRERRHREKEETRHKSSRSNSR 549



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 38/139 (27%), Positives = 62/139 (44%), Gaps = 23/139 (16%)

Query: 7   AREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKR---------SSDGNR---RRD 54
           AR  + R RERD  R    ++ R  DR R+R  +  R+R         +SD  R   R  
Sbjct: 455 ARREKDRDRERDRDR----ERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREY 510

Query: 55  GDRDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGE-HGVWEKPRQS 113
            +R  ER +      +R+R+R R RE+E    +  R ++ R      G+ H   +  +  
Sbjct: 511 AERGYERHRASREKEERHRER-RHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSK 569

Query: 114 RTRDGARGLTWDAAAPPGP 132
           R+++G      +A + P P
Sbjct: 570 RSKEGK-----EAGSEPAP 583


>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
          sapiens]
          Length = 820

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 33/87 (37%), Positives = 44/87 (50%), Gaps = 4/87 (4%)

Query: 12 ARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDR 71
          A P + +  R   PD+ R  DR R       RKR    +RRR G R   R + +   R+R
Sbjct: 13 ASPSKEERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKSAERER 72

Query: 72 NRDRERERERERD---PDRGPRRDTHR 95
           R +ERER++ERD    DR   +D HR
Sbjct: 73 -RHKERERDKERDRNKKDRDRDKDGHR 98



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 38/118 (32%), Positives = 58/118 (49%), Gaps = 13/118 (11%)

Query: 3   DPSGAREPRARPR------ERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGD 56
           D S ++E R R R      +RD  R+  P + R   R RDR     R RS   ++  + +
Sbjct: 12  DASPSKEERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKSAERE 71

Query: 57  RDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSR 114
           R   +++ERD  RDRN+   ++R+R++D   G RRD  R     +   G   K R+ R
Sbjct: 72  RR-HKERERDKERDRNK---KDRDRDKD---GHRRDKDRKRSSLSPGRGKDFKSRKDR 122



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 55/203 (27%), Positives = 92/203 (45%), Gaps = 30/203 (14%)

Query: 2   EDPSGAREP-RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGN-----RRRDG 55
           E+   +R P R R R+RD    P  D+ R   R R R G   R RS   +     R ++ 
Sbjct: 18  EERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKSAERERRHKER 77

Query: 56  DRDPERDQ---ERDGNRDRNRDRERERERER-DPDRGPRRDTHRDAGPR---AGEHGVWE 108
           +RD ERD+   +RD ++D +R R+++R+R    P RG    + +D   +     EHG  +
Sbjct: 78  ERDKERDRNKKDRDRDKDGHR-RDKDRKRSSLSPGRGKDFKSRKDRDSKKDEEDEHGD-K 135

Query: 109 KPRQSRTRDGARGLTWDAAAPPGPAPWEAPEPP----QPQRKGDPGRRRPESEPPSERYL 164
           KP+       A+ L+ +       A  EA   P    + +R+ +  +RR +     +R L
Sbjct: 136 KPK-------AQPLSLEELLAKKKAEEEAEAKPKFLSKAEREAEALKRRQQEVEERQRML 188

Query: 165 PSTPRPGREEVEYYQSEAEGLLE 187
                  R++ + +Q     +LE
Sbjct: 189 EEE----RKKRKQFQDLGRKMLE 207



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 30/85 (35%), Positives = 38/85 (44%), Gaps = 3/85 (3%)

Query: 38  PGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDRNRDRER--ERERERDPDRGPRRDTHR 95
           P    RKRS   +R RD DRD +    +D  R R+RDR R   R R R   +   R+   
Sbjct: 15  PSKEERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKSAERERRH 74

Query: 96  DAGPRAGEHGVWEKPRQSRTRDGAR 120
               R  E    +K R  R +DG R
Sbjct: 75  KERERDKERDRNKKDR-DRDKDGHR 98



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 24/81 (29%), Positives = 38/81 (46%), Gaps = 4/81 (4%)

Query: 40  DPRRKRSSDGNRRRDGDRDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGP 99
           D + + +S     R   R P+R+++RD +R  +  ++R+R R RD  RG  R   R    
Sbjct: 7   DKKDRDASPSKEERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSK 66

Query: 100 RAGEHGVWEKPRQSRTRDGAR 120
            A      E+  + R RD  R
Sbjct: 67  SAER----ERRHKERERDKER 83


>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
          Length = 709

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 36/78 (46%), Positives = 41/78 (52%), Gaps = 4/78 (5%)

Query: 15  RERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDRNRD 74
           R RD  +R H    R  D  R        +RS    R R+ +RD  RD  RD  RDR RD
Sbjct: 629 RYRD--KRVHDYDMRVDDFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRD 686

Query: 75  RERERER--ERDPDRGPR 90
           RERERER  +RD DRG R
Sbjct: 687 RERERERLCDRDRDRGER 704



 Score = 52.4 bits (124), Expect = 7e-07
 Identities = 37/98 (37%), Positives = 50/98 (51%), Gaps = 6/98 (6%)

Query: 7   AREPRARPRERDPGRRPHPDQGRTHD-RPRD---RPGDPRRKRSSDGNRRRDGDRDPERD 62
           A  P+A P     G  P P + R  D R  D   R  D  R+  +  + RR   R+ +R+
Sbjct: 609 APPPQAHPPYS--GHHPVPHEARYRDKRVHDYDMRVDDFLRRTQAVVSGRRSRPRERDRE 666

Query: 63  QERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPR 100
           +ERD  RD  RDRER+R R+R+ +R    D  RD G R
Sbjct: 667 RERDRPRDNRRDRERDRGRDRERERERLCDRDRDRGER 704



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 35/117 (29%), Positives = 49/117 (41%), Gaps = 15/117 (12%)

Query: 6   GAREPRARP--RERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRD--------- 54
           G  +P   P  +   P  + HP     H  P +     R KR  D + R D         
Sbjct: 595 GMEQPPHHPYYQHHAPPPQAHPPYSGHHPVPHE--ARYRDKRVHDYDMRVDDFLRRTQAV 652

Query: 55  --GDRDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEK 109
             G R   R+++R+  RDR RD  R+RER+R  DR   R+   D     GE G + +
Sbjct: 653 VSGRRSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRGERGRYRR 709


>gi|10190682 chromobox homolog 8 [Homo sapiens]
          Length = 389

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 29/60 (48%), Positives = 38/60 (63%), Gaps = 2/60 (3%)

Query: 53  RDGDRDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQ 112
           RD DRD +RD+ERD  R+R R+RERERERER+ +RG  R   + + P         KPR+
Sbjct: 148 RDRDRDRDRDRERD--RERERERERERERERERERGTSRVDDKPSSPGDSSKKRGPKPRK 205



 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 10/81 (12%)

Query: 69  RDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGARGLTWDAAA 128
           RDR+RDR+R+RER+R+ +R   R+  R+     G   V +KP              D++ 
Sbjct: 148 RDRDRDRDRDRERDRERERERERERERERERERGTSRVDDKPSS----------PGDSSK 197

Query: 129 PPGPAPWEAPEPPQPQRKGDP 149
             GP P +    P  +  G+P
Sbjct: 198 KRGPKPRKELPDPSQRPLGEP 218



 Score = 34.3 bits (77), Expect = 0.21
 Identities = 23/75 (30%), Positives = 33/75 (44%), Gaps = 21/75 (28%)

Query: 26  DQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDRNRDRERERERERDP 85
           D+ R  D                    RD +RD ER++ER+  R+R R+RER   R  D 
Sbjct: 149 DRDRDRD--------------------RDRERDRERERERERERERERERERGTSRVDDK 188

Query: 86  DRGPRRDTHRDAGPR 100
              P  D+ +  GP+
Sbjct: 189 PSSP-GDSSKKRGPK 202



 Score = 33.5 bits (75), Expect = 0.35
 Identities = 24/84 (28%), Positives = 36/84 (42%), Gaps = 11/84 (13%)

Query: 76  ERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQ-SRTRDGARGLTWDAAAPPGPAP 134
           E  R+R+RD DR   RD  R+           E+ R+  R R+  RG +     P  P  
Sbjct: 145 EAPRDRDRDRDRDRERDRERER----------ERERERERERERERGTSRVDDKPSSPGD 194

Query: 135 WEAPEPPQPQRKGDPGRRRPESEP 158
                 P+P+++     +RP  EP
Sbjct: 195 SSKKRGPKPRKELPDPSQRPLGEP 218


>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
          Length = 727

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 36/78 (46%), Positives = 41/78 (52%), Gaps = 4/78 (5%)

Query: 15  RERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDRNRD 74
           R RD  +R H    R  D  R        +RS    R R+ +RD  RD  RD  RDR RD
Sbjct: 647 RYRD--KRVHDYDMRVDDFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRD 704

Query: 75  RERERER--ERDPDRGPR 90
           RERERER  +RD DRG R
Sbjct: 705 RERERERLCDRDRDRGER 722



 Score = 52.4 bits (124), Expect = 7e-07
 Identities = 37/98 (37%), Positives = 50/98 (51%), Gaps = 6/98 (6%)

Query: 7   AREPRARPRERDPGRRPHPDQGRTHD-RPRD---RPGDPRRKRSSDGNRRRDGDRDPERD 62
           A  P+A P     G  P P + R  D R  D   R  D  R+  +  + RR   R+ +R+
Sbjct: 627 APPPQAHPPYS--GHHPVPHEARYRDKRVHDYDMRVDDFLRRTQAVVSGRRSRPRERDRE 684

Query: 63  QERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPR 100
           +ERD  RD  RDRER+R R+R+ +R    D  RD G R
Sbjct: 685 RERDRPRDNRRDRERDRGRDRERERERLCDRDRDRGER 722



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 35/117 (29%), Positives = 49/117 (41%), Gaps = 15/117 (12%)

Query: 6   GAREPRARP--RERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRD--------- 54
           G  +P   P  +   P  + HP     H  P +     R KR  D + R D         
Sbjct: 613 GMEQPPHHPYYQHHAPPPQAHPPYSGHHPVPHE--ARYRDKRVHDYDMRVDDFLRRTQAV 670

Query: 55  --GDRDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEK 109
             G R   R+++R+  RDR RD  R+RER+R  DR   R+   D     GE G + +
Sbjct: 671 VSGRRSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRGERGRYRR 727


>gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo
           sapiens]
          Length = 437

 Score = 52.8 bits (125), Expect = 6e-07
 Identities = 47/164 (28%), Positives = 69/164 (42%), Gaps = 21/164 (12%)

Query: 8   REPRARPRERDPGRRPHPDQGRTHDRPR---------DRPGDPRRKRSSDGNRRRDGDRD 58
           R+  +R  ER PG  P P + R  DR R         D+  + RR RS D  RR      
Sbjct: 213 RDDTSRYDER-PGPSPLPHRDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSRDK 271

Query: 59  PERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDG 118
            ER + R+ ++D++RDR+R   R R+     RR+  R    R G  G   +P ++     
Sbjct: 272 EERRRSRERSKDKDRDRKRRSSRSRE---RARRERERKEELRGG-GGDMAEPSEAGDAPP 327

Query: 119 ARGLTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSER 162
             G       PPG    + P+ P+ + +     RR       ER
Sbjct: 328 DDG-------PPGELGPDGPDGPEEKGRDRDRERRRSHRSERER 364



 Score = 49.3 bits (116), Expect = 6e-06
 Identities = 42/151 (27%), Positives = 55/151 (36%), Gaps = 48/151 (31%)

Query: 8   REPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRR-------------- 53
           R  R+R R R    R   ++ R+ +R +D+  D +R+ S    R R              
Sbjct: 255 RRSRSRDRRRRSRSRDKEERRRSRERSKDKDRDRKRRSSRSRERARRERERKEELRGGGG 314

Query: 54  -----------------------DGDRDPERDQERDGNRDRNRDRERERERERDPDRGPR 90
                                  DG   PE ++ RD +R+R R    ERER RD DR   
Sbjct: 315 DMAEPSEAGDAPPDDGPPGELGPDGPDGPE-EKGRDRDRERRRSHRSERERRRDRDRDRD 373

Query: 91  RDTHRDAGPRAGEHGVWEKPRQSRTRDGARG 121
           RD     G R  E G          RD ARG
Sbjct: 374 RDREHKRGERGSERG----------RDEARG 394



 Score = 48.9 bits (115), Expect = 8e-06
 Identities = 41/130 (31%), Positives = 55/130 (42%), Gaps = 26/130 (20%)

Query: 3   DPSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERD 62
           D    RE R R RERD  R       R   R RDR    R +   +  R R+  +D +RD
Sbjct: 234 DRDRERERRERSRERDKERE------RRRSRSRDRRRRSRSRDKEERRRSRERSKDKDRD 287

Query: 63  QERDGNRDRNRDRERERERERD------------------PDRGPRRDTHRDAGPRAGEH 104
           ++R  +R R R R RERER+ +                  PD GP  +   D GP   E 
Sbjct: 288 RKRRSSRSRERAR-RERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPD-GPDGPEE 345

Query: 105 GVWEKPRQSR 114
              ++ R+ R
Sbjct: 346 KGRDRDRERR 355



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 33/98 (33%), Positives = 42/98 (42%), Gaps = 6/98 (6%)

Query: 7   AREPRARPRERDPGRRPHPDQGRTHDRPRDR-PGDPRRKRSSDGNRRRDGDRDPERDQER 65
           AR  R R  E   G     +     D P D  P         DG   +  DRD ER +  
Sbjct: 299 ARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKGRDRDRERRRSH 358

Query: 66  DGNRDRNRDRERERERERDPDRGPR-----RDTHRDAG 98
              R+R RDR+R+R+R+R+  RG R     RD  R  G
Sbjct: 359 RSERERRRDRDRDRDRDREHKRGERGSERGRDEARGGG 396



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 54/171 (31%), Positives = 67/171 (39%), Gaps = 42/171 (24%)

Query: 26  DQGRTHD--RPRDRPGD--PRRKRSSDGNRRRDGDRDPERDQERDGNRDR-NRDRERERE 80
           ++GRT    RPR   G     R+  +D N R  G  D  R  ER G     +RDR+R+RE
Sbjct: 179 ERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSRYDERPGPSPLPHRDRDRDRE 238

Query: 81  -------RERDPDRGPRRDTHRDAGPRAGEHGVWE---------------KPRQSRTRDG 118
                  RERD +R  RR   RD   R+      E               K R SR+R+ 
Sbjct: 239 RERRERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKDRDRKRRSSRSRER 298

Query: 119 A----------RGLTWDAAAP--PGPAPWEAPEPPQPQRKGDPGRRRPESE 157
           A          RG   D A P   G AP   P+   P   G  G   PE +
Sbjct: 299 ARRERERKEELRGGGGDMAEPSEAGDAP---PDDGPPGELGPDGPDGPEEK 346



 Score = 35.8 bits (81), Expect = 0.071
 Identities = 29/85 (34%), Positives = 37/85 (43%), Gaps = 27/85 (31%)

Query: 4   PSGAREPRARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQ 63
           P G   P  + R+RD  RR      R+H   R+              RRRD DRD +RD+
Sbjct: 337 PDGPDGPEEKGRDRDRERR------RSHRSERE--------------RRRDRDRDRDRDR 376

Query: 64  ERDGNRDRNRDRERERERERDPDRG 88
           E       ++  ER  ER RD  RG
Sbjct: 377 E-------HKRGERGSERGRDEARG 394


>gi|74272284 membrane associated guanylate kinase, WW and PDZ domain
            containing 1 isoform c [Homo sapiens]
          Length = 1462

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 48/168 (28%), Positives = 66/168 (39%), Gaps = 32/168 (19%)

Query: 3    DPSGAREPRARPRERDP--GRRPHPDQGRTHDRPRDRPGDPRR----KRSSDGN------ 50
            DP G+RE   +P E     G    PD G    RP+DR  + RR    +R++  N      
Sbjct: 1265 DPKGSREYSRQPNEHHTWNGTSRKPDSGAC--RPKDRAPEGRRDAQAERAAAANGPKRRS 1322

Query: 51   --RRRDGDRDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWE 108
              +RR+G R  +   ER    ++ RD   ER RER P R       RD  P      +  
Sbjct: 1323 PEKRREGTRSADNTLERREKHEKRRDVSPERRRERSPTR------RRDGSPSRRRRSLER 1376

Query: 109  KPRQSRTRDGARGLTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPES 156
               Q R+ +  R          G +P    +    +R   P RRR  S
Sbjct: 1377 LLEQRRSPERRR----------GGSPERRAKSTDRRRARSPERRRERS 1414



 Score = 37.0 bits (84), Expect = 0.032
 Identities = 32/99 (32%), Positives = 42/99 (42%), Gaps = 7/99 (7%)

Query: 8    REPRARPRERD--PGRRPHPDQGRTHDR---PRDRPGDP-RRKRSSDGNRRRDGDRDPER 61
            R  R+  R RD  P RR    +     R    R R G P RR +S+D  R R  +R  ER
Sbjct: 1354 RRERSPTRRRDGSPSRRRRSLERLLEQRRSPERRRGGSPERRAKSTDRRRARSPERRRER 1413

Query: 62   DQERDGNRDRNRDRERERER-ERDPDRGPRRDTHRDAGP 99
              ++    DR   RERE    ++D  R  R    +   P
Sbjct: 1414 SLDKRNREDRASHREREEANLKQDAGRSSRHPPEQRRRP 1452


>gi|4826690 DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Homo sapiens]
          Length = 1220

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 37/103 (35%), Positives = 46/103 (44%), Gaps = 10/103 (9%)

Query: 35  RDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTH 94
           RDR    +R RS D NR RD DR+  RD++    R R+R R R R RER+  +   R   
Sbjct: 168 RDRTKKKKRSRSRDRNRDRDRDRERNRDRDHK-RRHRSRSRSRSRTRERNKVKSRYRSRS 226

Query: 95  RDAGPRAGEHGVWEKPRQSRTRDGARGL-TWDAAAPPGPAPWE 136
           R   P         K R+ R + G R L  W       P P E
Sbjct: 227 RSQSP--------PKDRKDRDKYGERNLDRWRDKHVDRPPPEE 261



 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 25/67 (37%), Positives = 39/67 (58%), Gaps = 1/67 (1%)

Query: 51  RRRDGD-RDPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEK 109
           ++RD + RD  + ++R  +RDRNRDR+R+RER RD D   R  +   +  R  E    + 
Sbjct: 161 KQRDAEHRDRTKKKKRSRSRDRNRDRDRDRERNRDRDHKRRHRSRSRSRSRTRERNKVKS 220

Query: 110 PRQSRTR 116
             +SR+R
Sbjct: 221 RYRSRSR 227



 Score = 45.4 bits (106), Expect = 9e-05
 Identities = 36/108 (33%), Positives = 48/108 (44%), Gaps = 15/108 (13%)

Query: 4   PSGAREPRARPRE-RDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERD 62
           PS A + + R  E RD  R     + R+ DR RDR  D  R R  D ++RR   R   R 
Sbjct: 154 PSAAGQEKQRDAEHRD--RTKKKKRSRSRDRNRDRDRDRERNRDRD-HKRRHRSRSRSRS 210

Query: 63  QERDGNRDRNRDRERERERERDPDRGPR-----------RDTHRDAGP 99
           + R+ N+ ++R R R R +    DR  R           RD H D  P
Sbjct: 211 RTRERNKVKSRYRSRSRSQSPPKDRKDRDKYGERNLDRWRDKHVDRPP 258



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 27/81 (33%), Positives = 37/81 (45%), Gaps = 2/81 (2%)

Query: 11  RARPRERDPGRRPHPDQGRTH-DRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQ-ERDGN 68
           R R R+RD  R    D  R H  R R R     R +     R R   + P +D+ +RD  
Sbjct: 182 RNRDRDRDRERNRDRDHKRRHRSRSRSRSRTRERNKVKSRYRSRSRSQSPPKDRKDRDKY 241

Query: 69  RDRNRDRERERERERDPDRGP 89
            +RN DR R++  +R P   P
Sbjct: 242 GERNLDRWRDKHVDRPPPEEP 262



 Score = 38.1 bits (87), Expect = 0.014
 Identities = 27/78 (34%), Positives = 39/78 (50%), Gaps = 2/78 (2%)

Query: 11  RARPRERDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQERDGNRD 70
           R R R+RD  RR H  + R+  R R+R     R RS   ++    DR  +RD+  + N D
Sbjct: 190 RERNRDRDHKRR-HRSRSRSRSRTRERNKVKSRYRSRSRSQSPPKDRK-DRDKYGERNLD 247

Query: 71  RNRDRERERERERDPDRG 88
           R RD+  +R    +P  G
Sbjct: 248 RWRDKHVDRPPPEEPTIG 265


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.140    0.444 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,229,793
Number of Sequences: 37866
Number of extensions: 1277270
Number of successful extensions: 17761
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 290
Number of HSP's successfully gapped in prelim test: 705
Number of HSP's that attempted gapping in prelim test: 9541
Number of HSP's gapped (non-prelim): 4512
length of query: 401
length of database: 18,247,518
effective HSP length: 104
effective length of query: 297
effective length of database: 14,309,454
effective search space: 4249907838
effective search space used: 4249907838
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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