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Search of human proteins with 63003907
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|63003907 protein phosphatase 1, regulatory subunit 13 like
[Homo sapiens]
(828 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|215820635 protein phosphatase 1, regulatory subunit 13 like [... 1707 0.0
gi|63003907 protein phosphatase 1, regulatory subunit 13 like [H... 1707 0.0
gi|121114287 apoptosis-stimulating protein of p53, 1 [Homo sapiens] 296 4e-80
gi|112799849 tumor protein p53 binding protein, 2 isoform 1 [Hom... 281 2e-75
gi|4885643 tumor protein p53 binding protein, 2 isoform 2 [Homo ... 281 2e-75
gi|163965366 nascent polypeptide-associated complex alpha subuni... 105 1e-22
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 102 1e-21
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 94 4e-19
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 94 7e-19
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 93 1e-18
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [... 85 2e-16
gi|28626517 protein phosphatase 1 regulatory inhibitor subunit 1... 84 4e-16
gi|14249672 protein phosphatase 1, regulatory (inhibitor) subuni... 83 9e-16
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 79 1e-14
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 79 2e-14
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 78 3e-14
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 78 3e-14
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap... 78 3e-14
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H... 77 7e-14
gi|14195601 protein phosphatase 1, regulatory (inhibitor) subuni... 76 1e-13
gi|4505319 protein phosphatase 1, regulatory (inhibitor) subunit... 76 1e-13
gi|14149716 protein phosphatase 1, regulatory subunit 12C [Homo ... 75 3e-13
gi|188536004 zinc finger protein 469 [Homo sapiens] 74 6e-13
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 74 6e-13
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 74 7e-13
gi|219842212 protein phosphatase 1, regulatory (inhibitor) subun... 73 9e-13
gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit... 73 9e-13
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 73 1e-12
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 73 1e-12
gi|150170670 piccolo isoform 2 [Homo sapiens] 72 2e-12
>gi|215820635 protein phosphatase 1, regulatory subunit 13 like
[Homo sapiens]
Length = 828
Score = 1707 bits (4422), Expect = 0.0
Identities = 828/828 (100%), Positives = 828/828 (100%)
Query: 1 MDSEAFQSARDFLDMNFQSLAMKHMDLKQMELDTAAAKVDELTKQLESLWSDSPAPPGPQ 60
MDSEAFQSARDFLDMNFQSLAMKHMDLKQMELDTAAAKVDELTKQLESLWSDSPAPPGPQ
Sbjct: 1 MDSEAFQSARDFLDMNFQSLAMKHMDLKQMELDTAAAKVDELTKQLESLWSDSPAPPGPQ 60
Query: 61 AGPPSRPPRYSSSSIPEPFGSRGSPRKAATDGADTPFGRSESAPTLHPYSPLSPKGRPSS 120
AGPPSRPPRYSSSSIPEPFGSRGSPRKAATDGADTPFGRSESAPTLHPYSPLSPKGRPSS
Sbjct: 61 AGPPSRPPRYSSSSIPEPFGSRGSPRKAATDGADTPFGRSESAPTLHPYSPLSPKGRPSS 120
Query: 121 PRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRAPSPRPGPGPLRQQGPPTPFDFLGR 180
PRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRAPSPRPGPGPLRQQGPPTPFDFLGR
Sbjct: 121 PRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRAPSPRPGPGPLRQQGPPTPFDFLGR 180
Query: 181 AGSPRGSPLAEGPQAFFPERGPSPRPPATAYDAPASAFGSSLLGSGGSAFAPPLRAQDDL 240
AGSPRGSPLAEGPQAFFPERGPSPRPPATAYDAPASAFGSSLLGSGGSAFAPPLRAQDDL
Sbjct: 181 AGSPRGSPLAEGPQAFFPERGPSPRPPATAYDAPASAFGSSLLGSGGSAFAPPLRAQDDL 240
Query: 241 TLRRRPPKAWNESDLDVAYEKKPSQTASYERLDVFARPASPSLQLLPWRESSLDGLGGTG 300
TLRRRPPKAWNESDLDVAYEKKPSQTASYERLDVFARPASPSLQLLPWRESSLDGLGGTG
Sbjct: 241 TLRRRPPKAWNESDLDVAYEKKPSQTASYERLDVFARPASPSLQLLPWRESSLDGLGGTG 300
Query: 301 KDNLTSATLPRNYKVSPLASDRRSDAGSYRRSLGSAGPSGTLPRSWQPVSRIPMPPSSPQ 360
KDNLTSATLPRNYKVSPLASDRRSDAGSYRRSLGSAGPSGTLPRSWQPVSRIPMPPSSPQ
Sbjct: 301 KDNLTSATLPRNYKVSPLASDRRSDAGSYRRSLGSAGPSGTLPRSWQPVSRIPMPPSSPQ 360
Query: 361 PRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLPGSPLFTRAPPPKLQPQPQPQPQPQSQP 420
PRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLPGSPLFTRAPPPKLQPQPQPQPQPQSQP
Sbjct: 361 PRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLPGSPLFTRAPPPKLQPQPQPQPQPQSQP 420
Query: 421 QPQLPPQPQTQPQTPTPAPQHPQQTWPPVNEGPPKPPTELEPEPEIEGLLTPVLEAGDVD 480
QPQLPPQPQTQPQTPTPAPQHPQQTWPPVNEGPPKPPTELEPEPEIEGLLTPVLEAGDVD
Sbjct: 421 QPQLPPQPQTQPQTPTPAPQHPQQTWPPVNEGPPKPPTELEPEPEIEGLLTPVLEAGDVD 480
Query: 481 EGPVARPLSPTRLQPALPPEAQSVPELEEVARVLAEIPRPLKRRGSMEQAPAVALPPTHK 540
EGPVARPLSPTRLQPALPPEAQSVPELEEVARVLAEIPRPLKRRGSMEQAPAVALPPTHK
Sbjct: 481 EGPVARPLSPTRLQPALPPEAQSVPELEEVARVLAEIPRPLKRRGSMEQAPAVALPPTHK 540
Query: 541 KQYQQIISRLFHRHGGPGPGGPEPELSPITEGSEARAGPPAPAPPAPIPPPAPSQSSPPE 600
KQYQQIISRLFHRHGGPGPGGPEPELSPITEGSEARAGPPAPAPPAPIPPPAPSQSSPPE
Sbjct: 541 KQYQQIISRLFHRHGGPGPGGPEPELSPITEGSEARAGPPAPAPPAPIPPPAPSQSSPPE 600
Query: 601 QPQSMEMRSVLRKAGSPRKARRARLNPLVLLLDAALTGELEVVQQAVKEMNDPSQPNEEG 660
QPQSMEMRSVLRKAGSPRKARRARLNPLVLLLDAALTGELEVVQQAVKEMNDPSQPNEEG
Sbjct: 601 QPQSMEMRSVLRKAGSPRKARRARLNPLVLLLDAALTGELEVVQQAVKEMNDPSQPNEEG 660
Query: 661 ITALHNAICGANYSIVDFLITAGANVNSPDSHGWTPLHCAASCNDTVICMALVQHGAAIF 720
ITALHNAICGANYSIVDFLITAGANVNSPDSHGWTPLHCAASCNDTVICMALVQHGAAIF
Sbjct: 661 ITALHNAICGANYSIVDFLITAGANVNSPDSHGWTPLHCAASCNDTVICMALVQHGAAIF 720
Query: 721 ATTLSDGATAFEKCDPYREGYADCATYLADVEQSMGLMNSGAVYALWDYSAEFGDELSFR 780
ATTLSDGATAFEKCDPYREGYADCATYLADVEQSMGLMNSGAVYALWDYSAEFGDELSFR
Sbjct: 721 ATTLSDGATAFEKCDPYREGYADCATYLADVEQSMGLMNSGAVYALWDYSAEFGDELSFR 780
Query: 781 EGESVTVLRRDGPEETDWWWAALHGQEGYVPRNYFGLFPRVKPQRSKV 828
EGESVTVLRRDGPEETDWWWAALHGQEGYVPRNYFGLFPRVKPQRSKV
Sbjct: 781 EGESVTVLRRDGPEETDWWWAALHGQEGYVPRNYFGLFPRVKPQRSKV 828
>gi|63003907 protein phosphatase 1, regulatory subunit 13 like [Homo
sapiens]
Length = 828
Score = 1707 bits (4422), Expect = 0.0
Identities = 828/828 (100%), Positives = 828/828 (100%)
Query: 1 MDSEAFQSARDFLDMNFQSLAMKHMDLKQMELDTAAAKVDELTKQLESLWSDSPAPPGPQ 60
MDSEAFQSARDFLDMNFQSLAMKHMDLKQMELDTAAAKVDELTKQLESLWSDSPAPPGPQ
Sbjct: 1 MDSEAFQSARDFLDMNFQSLAMKHMDLKQMELDTAAAKVDELTKQLESLWSDSPAPPGPQ 60
Query: 61 AGPPSRPPRYSSSSIPEPFGSRGSPRKAATDGADTPFGRSESAPTLHPYSPLSPKGRPSS 120
AGPPSRPPRYSSSSIPEPFGSRGSPRKAATDGADTPFGRSESAPTLHPYSPLSPKGRPSS
Sbjct: 61 AGPPSRPPRYSSSSIPEPFGSRGSPRKAATDGADTPFGRSESAPTLHPYSPLSPKGRPSS 120
Query: 121 PRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRAPSPRPGPGPLRQQGPPTPFDFLGR 180
PRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRAPSPRPGPGPLRQQGPPTPFDFLGR
Sbjct: 121 PRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRAPSPRPGPGPLRQQGPPTPFDFLGR 180
Query: 181 AGSPRGSPLAEGPQAFFPERGPSPRPPATAYDAPASAFGSSLLGSGGSAFAPPLRAQDDL 240
AGSPRGSPLAEGPQAFFPERGPSPRPPATAYDAPASAFGSSLLGSGGSAFAPPLRAQDDL
Sbjct: 181 AGSPRGSPLAEGPQAFFPERGPSPRPPATAYDAPASAFGSSLLGSGGSAFAPPLRAQDDL 240
Query: 241 TLRRRPPKAWNESDLDVAYEKKPSQTASYERLDVFARPASPSLQLLPWRESSLDGLGGTG 300
TLRRRPPKAWNESDLDVAYEKKPSQTASYERLDVFARPASPSLQLLPWRESSLDGLGGTG
Sbjct: 241 TLRRRPPKAWNESDLDVAYEKKPSQTASYERLDVFARPASPSLQLLPWRESSLDGLGGTG 300
Query: 301 KDNLTSATLPRNYKVSPLASDRRSDAGSYRRSLGSAGPSGTLPRSWQPVSRIPMPPSSPQ 360
KDNLTSATLPRNYKVSPLASDRRSDAGSYRRSLGSAGPSGTLPRSWQPVSRIPMPPSSPQ
Sbjct: 301 KDNLTSATLPRNYKVSPLASDRRSDAGSYRRSLGSAGPSGTLPRSWQPVSRIPMPPSSPQ 360
Query: 361 PRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLPGSPLFTRAPPPKLQPQPQPQPQPQSQP 420
PRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLPGSPLFTRAPPPKLQPQPQPQPQPQSQP
Sbjct: 361 PRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLPGSPLFTRAPPPKLQPQPQPQPQPQSQP 420
Query: 421 QPQLPPQPQTQPQTPTPAPQHPQQTWPPVNEGPPKPPTELEPEPEIEGLLTPVLEAGDVD 480
QPQLPPQPQTQPQTPTPAPQHPQQTWPPVNEGPPKPPTELEPEPEIEGLLTPVLEAGDVD
Sbjct: 421 QPQLPPQPQTQPQTPTPAPQHPQQTWPPVNEGPPKPPTELEPEPEIEGLLTPVLEAGDVD 480
Query: 481 EGPVARPLSPTRLQPALPPEAQSVPELEEVARVLAEIPRPLKRRGSMEQAPAVALPPTHK 540
EGPVARPLSPTRLQPALPPEAQSVPELEEVARVLAEIPRPLKRRGSMEQAPAVALPPTHK
Sbjct: 481 EGPVARPLSPTRLQPALPPEAQSVPELEEVARVLAEIPRPLKRRGSMEQAPAVALPPTHK 540
Query: 541 KQYQQIISRLFHRHGGPGPGGPEPELSPITEGSEARAGPPAPAPPAPIPPPAPSQSSPPE 600
KQYQQIISRLFHRHGGPGPGGPEPELSPITEGSEARAGPPAPAPPAPIPPPAPSQSSPPE
Sbjct: 541 KQYQQIISRLFHRHGGPGPGGPEPELSPITEGSEARAGPPAPAPPAPIPPPAPSQSSPPE 600
Query: 601 QPQSMEMRSVLRKAGSPRKARRARLNPLVLLLDAALTGELEVVQQAVKEMNDPSQPNEEG 660
QPQSMEMRSVLRKAGSPRKARRARLNPLVLLLDAALTGELEVVQQAVKEMNDPSQPNEEG
Sbjct: 601 QPQSMEMRSVLRKAGSPRKARRARLNPLVLLLDAALTGELEVVQQAVKEMNDPSQPNEEG 660
Query: 661 ITALHNAICGANYSIVDFLITAGANVNSPDSHGWTPLHCAASCNDTVICMALVQHGAAIF 720
ITALHNAICGANYSIVDFLITAGANVNSPDSHGWTPLHCAASCNDTVICMALVQHGAAIF
Sbjct: 661 ITALHNAICGANYSIVDFLITAGANVNSPDSHGWTPLHCAASCNDTVICMALVQHGAAIF 720
Query: 721 ATTLSDGATAFEKCDPYREGYADCATYLADVEQSMGLMNSGAVYALWDYSAEFGDELSFR 780
ATTLSDGATAFEKCDPYREGYADCATYLADVEQSMGLMNSGAVYALWDYSAEFGDELSFR
Sbjct: 721 ATTLSDGATAFEKCDPYREGYADCATYLADVEQSMGLMNSGAVYALWDYSAEFGDELSFR 780
Query: 781 EGESVTVLRRDGPEETDWWWAALHGQEGYVPRNYFGLFPRVKPQRSKV 828
EGESVTVLRRDGPEETDWWWAALHGQEGYVPRNYFGLFPRVKPQRSKV
Sbjct: 781 EGESVTVLRRDGPEETDWWWAALHGQEGYVPRNYFGLFPRVKPQRSKV 828
>gi|121114287 apoptosis-stimulating protein of p53, 1 [Homo sapiens]
Length = 1090
Score = 296 bits (759), Expect = 4e-80
Identities = 259/853 (30%), Positives = 368/853 (43%), Gaps = 114/853 (13%)
Query: 25 MDLKQMELDTAAAKVDELTKQLESL--------WSDSPAPPGPQAGPPSRPPRYSSSSIP 76
++ + ME+ ++ EL ++L + SP P +G + Y
Sbjct: 296 LNKRNMEVAMMDKRISELRERLYGKKIQLNRVNGTSSPQSPLSTSGRVAAVGPYIQVPSA 355
Query: 77 EPFGSRGSPRK--AATDGADTPFGRSESA-----PTLHPYSPLSPKGRPSSPRTPLYLQP 129
F G P K + + ++ GRS+SA PTL S S K P + P
Sbjct: 356 GSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNWPTLKQNSSSSVK--PVQVAGADWKDP 413
Query: 130 DAYGSLDRAT-SPRPRAFDGAGSS------LGRAPSPRPGPGPLRQQGPPTPFDFLGRAG 182
GS+ + T S +P F G + +G+ P P PG G +Q PP+ +
Sbjct: 414 SVEGSVKQGTVSSQPVPFSALGPTEKPGIEIGKVPPPIPGVG---KQLPPSYGTY----- 465
Query: 183 SPRGSPLAEGPQAFFPER--GPSPRPPATAYDAPASAFGSSLLGSGGSAFAPPLRAQDDL 240
P +PL G + R G PRP A S +LL + GS P Q
Sbjct: 466 -PSPTPLGPGSTSSLERRKEGSLPRPSAGL----PSRQRPTLLPATGSTPQPGSSQQIQQ 520
Query: 241 TLRRRPPKAWNESDLDV--AYEKKPSQTASYE----RLDVFARPASPSLQLLPWRESSLD 294
+ P + + A + KP + D +RP SP SS+
Sbjct: 521 RISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIY 580
Query: 295 GLGGTGKDNLTSATLPRNYKVSPLASDRRSDAGSYRRSL---GSAGPSGT--LPRSWQPV 349
+ L AT P+NY+ + ++ +S Y + + GS PS L S
Sbjct: 581 SM------YLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSPSPLPFLHGSLSTG 634
Query: 350 SRIPMPPSSP---QPRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLPGSPLFTRAPPP-- 404
+ P PPS +P P S + L + SPL ++
Sbjct: 635 TPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRPL--SPTKLTPIVHSPLRYQSDADLE 692
Query: 405 ----KLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPPVNEGPPKPPT-E 459
KL P+P + S +P+ P P Q Q + + G P +
Sbjct: 693 ALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLL--------YQRFNTLAGGMEGTPFYQ 744
Query: 460 LEPEPEIEGLLTPVLEA-----GDVDEGPVARPLSPTRLQPALPPEAQSVPELEEVARVL 514
P + G L V G+++E P A+P +P +PA +A
Sbjct: 745 PSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSSDAND----------- 793
Query: 515 AEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPELSPITEGSE 574
E+P P Q P + P P P +
Sbjct: 794 NELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSPGEEQV----- 848
Query: 575 ARAGPPAPAPPAPIPPPAPSQSSPPEQPQSMEMRSVLRKAGSPRKAR--RARLNPLVLLL 632
PPAP PPA PP S R+ L+K S R R R NPL LLL
Sbjct: 849 ----PPAPLPPASHPPAT-----------STNKRTNLKKPNSERTGHGLRVRFNPLALLL 893
Query: 633 DAALTGELEVVQQAVKEMNDPSQPNEEGITALHNAICGANYSIVDFLITAGANVNSPDSH 692
DA+L GE ++VQ+ + E+ DPS+PN+EGIT LHNA+C ++ IV FL+ G NVN+ DS
Sbjct: 894 DASLEGEFDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVKFLLDFGVNVNAADSD 953
Query: 693 GWTPLHCAASCNDTVICMALVQHGAAIFATTLSDGATAFEKCDPYREGYADCATYLADVE 752
GWTPLHCAASCN +C LV+ GAAIFA+T+SD TA +KC+ EGY C+ +L V+
Sbjct: 954 GWTPLHCAASCNSVHLCKQLVESGAAIFASTISDIETAADKCEEMEEGYIQCSQFLYGVQ 1013
Query: 753 QSMGLMNSGAVYALWDYSAEFGDELSFREGESVTVLRRDGPEETDWWWAALHGQEGYVPR 812
+ +G+MN G YALWDY A+ DELSF EG+++T+LRR ET+WWWA L +EGYVP+
Sbjct: 1014 EKLGVMNKGVAYALWDYEAQNSDELSFHEGDALTILRRKDESETEWWWARLGDREGYVPK 1073
Query: 813 NYFGLFPRVKPQR 825
N GL+PR+KP++
Sbjct: 1074 NLLGLYPRIKPRQ 1086
>gi|112799849 tumor protein p53 binding protein, 2 isoform 1 [Homo
sapiens]
Length = 1134
Score = 281 bits (718), Expect = 2e-75
Identities = 235/806 (29%), Positives = 346/806 (42%), Gaps = 125/806 (15%)
Query: 56 PPGPQAGPPSRP--PRYSSSSIPEPFGSRGSPRKAATDGADTPFGRSESAPTLHPYSPLS 113
P GP P + P S+S+P+ S G+ DG + P E + P+S
Sbjct: 414 PVGPDWSPSNADLFPSQGSASVPQ---STGNALDQVDDG-EVPLREKEKK--VRPFSMFD 467
Query: 114 PKGRPSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRAPSPRPGPGPLRQQGPPT 173
+ ++P ++G+L + S D ++ A P P P +Q P
Sbjct: 468 AVDQSNAP--------PSFGTLRKNQSSEDILRDAQVANKNVAKVPPPVPTKPKQINLP- 518
Query: 174 PFDFLGRAGSPRGSPLAEGPQ----AFFPERGPSPRPPATAYDAPASAFGSSLLGSG-GS 228
+ G+ P +G P G P+P A P S+ G
Sbjct: 519 ---YFGQTNQPPSDIKPDGSSQQLSTVVPSMGTKPKP---AGQQPRVLLSPSIPSVGQDQ 572
Query: 229 AFAPPLRAQDDLTLRRRPPKAWNESDLDVAYEKKPSQTASYERLDVFARPASPSLQLLPW 288
+P + + RP D + +KP A+ ++ + +P
Sbjct: 573 TLSPGSKQESPPAAAVRPFTPQPSKDTLLPPFRKPQTVAASSIYSMYTQQQAPGKNFQQA 632
Query: 289 RESSLDGLGGTGKDNLTSATLPRNYKVSPLASDRRSDAGSYRRSLGSAGPSGTLPRSWQP 348
+S+L G + P ++ + ++ Y S G G S +P
Sbjct: 633 VQSALTKTHTRGPHFSSVYGKP---VIAAAQNQQQHPENIYSNSQGKPG-------SPEP 682
Query: 349 VSRIPMPPSSPQPRGAPRQRPIPLS---MIFKLQNAFWEHGASRAMLPGSPLFTRAPPPK 405
+ P SS Q + P PLS ++ L N + S A K
Sbjct: 683 ETE---PVSSVQENHENERIPRPLSPTKLLPFLSNPYRNQ---------SDADLEALRKK 730
Query: 406 LQPQPQPQPQPQSQPQPQLPPQPQTQP---QTPTPA-------PQHPQQTWPPV--NEGP 453
L P+P + S +P+ P P Q Q T A P +P ++ +E P
Sbjct: 731 LSNAPRPLKKRSSITEPEGPNGPNIQKLLYQRTTIAAMETISVPSYPSKSASVTASSESP 790
Query: 454 PK---PPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPALPPEAQSVPELEEV 510
+ P +EPE E+ L+ L DV P P L E + VP+
Sbjct: 791 VEIQNPYLHVEPEKEVVSLVPESLSPEDVGNASTENSDMPAP-SPGLDYEPEGVPDNSPN 849
Query: 511 ARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPELSPIT 570
+ E P P +AP V + ++Y
Sbjct: 850 LQNNPEEPNP--------EAPHVL--DVYLEEY--------------------------- 872
Query: 571 EGSEARAGPPAPAPPAPI-PPPAPSQSS----PPEQPQSMEM----RSVLRKAGSPRKAR 621
PP P PP P P P + S PPE + + R+ LRK GS R A
Sbjct: 873 --------PPYPPPPYPSGEPEGPGEDSVSMRPPEITGQVSLPPGKRTNLRKTGSERIAH 924
Query: 622 --RARLNPLVLLLDAALTGELEVVQQAVKEMNDPSQPNEEGITALHNAICGANYSIVDFL 679
R + NPL LLLD++L GE ++VQ+ + E++DPS PN+EGITALHNA+C + IV FL
Sbjct: 925 GMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFL 984
Query: 680 ITAGANVNSPDSHGWTPLHCAASCNDTVICMALVQHGAAIFATTLSDGATAFEKCDPYRE 739
+ G NVN+ DS GWTPLHCAASCN+ +C LV+ GAA+FA T SD TA +KC+ E
Sbjct: 985 VQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTYSDMQTAADKCEEMEE 1044
Query: 740 GYADCATYLADVEQSMGLMNSGAVYALWDYSAEFGDELSFREGESVTVLRRDGPEETDWW 799
GY C+ +L V++ MG+MN G +YALWDY + DEL +EG+ +T++ R+ +E +WW
Sbjct: 1045 GYTQCSQFLYGVQEKMGIMNKGVIYALWDYEPQNDDELPMKEGDCMTIIHREDEDEIEWW 1104
Query: 800 WAALHGQEGYVPRNYFGLFPRVKPQR 825
WA L+ +EGYVPRN GL+PR+KP++
Sbjct: 1105 WARLNDKEGYVPRNLLGLYPRIKPRQ 1130
>gi|4885643 tumor protein p53 binding protein, 2 isoform 2 [Homo
sapiens]
Length = 1005
Score = 281 bits (718), Expect = 2e-75
Identities = 235/806 (29%), Positives = 346/806 (42%), Gaps = 125/806 (15%)
Query: 56 PPGPQAGPPSRP--PRYSSSSIPEPFGSRGSPRKAATDGADTPFGRSESAPTLHPYSPLS 113
P GP P + P S+S+P+ S G+ DG + P E + P+S
Sbjct: 285 PVGPDWSPSNADLFPSQGSASVPQ---STGNALDQVDDG-EVPLREKEKK--VRPFSMFD 338
Query: 114 PKGRPSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRAPSPRPGPGPLRQQGPPT 173
+ ++P ++G+L + S D ++ A P P P +Q P
Sbjct: 339 AVDQSNAP--------PSFGTLRKNQSSEDILRDAQVANKNVAKVPPPVPTKPKQINLP- 389
Query: 174 PFDFLGRAGSPRGSPLAEGPQ----AFFPERGPSPRPPATAYDAPASAFGSSLLGSG-GS 228
+ G+ P +G P G P+P A P S+ G
Sbjct: 390 ---YFGQTNQPPSDIKPDGSSQQLSTVVPSMGTKPKP---AGQQPRVLLSPSIPSVGQDQ 443
Query: 229 AFAPPLRAQDDLTLRRRPPKAWNESDLDVAYEKKPSQTASYERLDVFARPASPSLQLLPW 288
+P + + RP D + +KP A+ ++ + +P
Sbjct: 444 TLSPGSKQESPPAAAVRPFTPQPSKDTLLPPFRKPQTVAASSIYSMYTQQQAPGKNFQQA 503
Query: 289 RESSLDGLGGTGKDNLTSATLPRNYKVSPLASDRRSDAGSYRRSLGSAGPSGTLPRSWQP 348
+S+L G + P ++ + ++ Y S G G S +P
Sbjct: 504 VQSALTKTHTRGPHFSSVYGKP---VIAAAQNQQQHPENIYSNSQGKPG-------SPEP 553
Query: 349 VSRIPMPPSSPQPRGAPRQRPIPLS---MIFKLQNAFWEHGASRAMLPGSPLFTRAPPPK 405
+ P SS Q + P PLS ++ L N + S A K
Sbjct: 554 ETE---PVSSVQENHENERIPRPLSPTKLLPFLSNPYRNQ---------SDADLEALRKK 601
Query: 406 LQPQPQPQPQPQSQPQPQLPPQPQTQP---QTPTPA-------PQHPQQTWPPV--NEGP 453
L P+P + S +P+ P P Q Q T A P +P ++ +E P
Sbjct: 602 LSNAPRPLKKRSSITEPEGPNGPNIQKLLYQRTTIAAMETISVPSYPSKSASVTASSESP 661
Query: 454 PK---PPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPALPPEAQSVPELEEV 510
+ P +EPE E+ L+ L DV P P L E + VP+
Sbjct: 662 VEIQNPYLHVEPEKEVVSLVPESLSPEDVGNASTENSDMPAP-SPGLDYEPEGVPDNSPN 720
Query: 511 ARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPELSPIT 570
+ E P P +AP V + ++Y
Sbjct: 721 LQNNPEEPNP--------EAPHVL--DVYLEEY--------------------------- 743
Query: 571 EGSEARAGPPAPAPPAPI-PPPAPSQSS----PPEQPQSMEM----RSVLRKAGSPRKAR 621
PP P PP P P P + S PPE + + R+ LRK GS R A
Sbjct: 744 --------PPYPPPPYPSGEPEGPGEDSVSMRPPEITGQVSLPPGKRTNLRKTGSERIAH 795
Query: 622 --RARLNPLVLLLDAALTGELEVVQQAVKEMNDPSQPNEEGITALHNAICGANYSIVDFL 679
R + NPL LLLD++L GE ++VQ+ + E++DPS PN+EGITALHNA+C + IV FL
Sbjct: 796 GMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFL 855
Query: 680 ITAGANVNSPDSHGWTPLHCAASCNDTVICMALVQHGAAIFATTLSDGATAFEKCDPYRE 739
+ G NVN+ DS GWTPLHCAASCN+ +C LV+ GAA+FA T SD TA +KC+ E
Sbjct: 856 VQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTYSDMQTAADKCEEMEE 915
Query: 740 GYADCATYLADVEQSMGLMNSGAVYALWDYSAEFGDELSFREGESVTVLRRDGPEETDWW 799
GY C+ +L V++ MG+MN G +YALWDY + DEL +EG+ +T++ R+ +E +WW
Sbjct: 916 GYTQCSQFLYGVQEKMGIMNKGVIYALWDYEPQNDDELPMKEGDCMTIIHREDEDEIEWW 975
Query: 800 WAALHGQEGYVPRNYFGLFPRVKPQR 825
WA L+ +EGYVPRN GL+PR+KP++
Sbjct: 976 WARLNDKEGYVPRNLLGLYPRIKPRQ 1001
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 105 bits (263), Expect = 1e-22
Identities = 149/591 (25%), Positives = 219/591 (37%), Gaps = 95/591 (16%)
Query: 50 WSDSP---APPGPQAGP----PSRPPRYSSSSIPEPFGSRG--SPRKAATDGADTPFGRS 100
W+ +P PP P+ GP P P +++ P P G SP+ A T A TP
Sbjct: 961 WAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTP-PSP 1019
Query: 101 ESAPTLHPY----------SPLSPKGRPSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAG 150
+ +P P+ +P SPKG P++ TPL P + AT P P+ A
Sbjct: 1020 KGSPAATPFPKGASTPPAATPPSPKGSPAA--TPL---PKGAPTTPAATLPSPKG-GPAT 1073
Query: 151 SSLGRAPSPRPGPGPLRQQGPPTPFDFLGRAGSPRGSPLAEGPQAFFPERGPSPRPPATA 210
SL AP+P P + GP TP SP+G+P+ P+ G + P A
Sbjct: 1074 PSLKGAPTPPAATPPSPKGGPATP--------SPKGAPMPPAATPPSPKGGLATPPHKGA 1125
Query: 211 YDAPASAFGSSLLGSGGSAFAPPLRAQDDLTLRRRPPKAWNESDLDVAYEKKPSQTASYE 270
PA+ S GG A PP A PK + P+ T
Sbjct: 1126 PTTPAATPPSP---KGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSP 1182
Query: 271 RLDVFARPASPSLQLLPWRESSLDGLGGTGKDNLTSATLPRNYKVSPLASDRRSDAGSYR 330
+ + A+PS + P ++ + K L + + P+ +P A+ G
Sbjct: 1183 KGGL----ATPSPKGAPTTPAATPP---SPKGGLATPS-PKGAPTTPAATPPSPKGG--- 1231
Query: 331 RSLGSAGPSGTLPRSWQPVSRIPMP---PSSPQPRGAPRQRPIPLSMIFKLQNAFWEHGA 387
L + P G P + P P P++P P+GAP P + L+
Sbjct: 1232 --LATPSPKGA---PTTPAATPPSPKGGPATPPPKGAPTP---PAATPPSLKGGL----- 1278
Query: 388 SRAMLPGSPLFTRAPPPKLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWP 447
+P AP P + P P+ P + P P P P +P +P P P
Sbjct: 1279 ------ATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTP----P 1328
Query: 448 PVNEGPPKPPTELEPEPEIEGLL---TPVLEAGDVD----EGPVARPLSPTR-----LQP 495
P +G P PP P P+ L TP + G EGP +P+ + P
Sbjct: 1329 P--KGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTP 1386
Query: 496 ALPPEAQSVPELEEVARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHG 555
P ++P + A IP K+ + A P+ ++ + +
Sbjct: 1387 PSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKA 1446
Query: 556 GPGPGGPEPELSPITEGSEARAGPPAPAPPAPIPPPAPSQ----SSPPEQP 602
P P+ P T S+ PA PP+P PPAP Q SSP + P
Sbjct: 1447 ---PATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAP 1494
Score = 102 bits (254), Expect = 1e-21
Identities = 165/631 (26%), Positives = 227/631 (35%), Gaps = 83/631 (13%)
Query: 28 KQMELDTAAAKVDELTKQLESLWSDSPAPPGPQAGPPS-RPPRYSSSSIPE-PFGSRGSP 85
K+ + + A +K + +DSP+P G P + RPP S+ P+ P G+ SP
Sbjct: 768 KECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSP 827
Query: 86 -----RKAATDGADTPFGRSESAPTLHPYSPLSPKGRPSSPRTPLYLQPDAYGSLDRATS 140
+ + + G +S T H +P SPKG P +P L P +L +
Sbjct: 828 VSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAP-TPSAVTPLSPKGV-TLPPKET 885
Query: 141 PRPRAFDGAGSSLGRA-PSPRPGP-------GPLRQQGPPTPFDFLGRAGSPRGSPLAEG 192
P P + G A P+P+ P P + + P P + + SP+G+P
Sbjct: 886 PTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAP-KGIPASPSPKGAPTPPA 944
Query: 193 PQAFFPERGPSPRPPATAYDAPASAFGSSLLGSGGSAFAPPLRAQDDLTLRRRPPKAWNE 252
P+ GP+ P A PA+ S GG A P A PP A
Sbjct: 945 ATPPSPKGGPATPSPKWAPTPPAATPPSP---KGGPATPSPKGAP-------TPPAATPP 994
Query: 253 SDLDVAYEKKPSQTASYERLDVFARPASPSLQLLPWRESSLDGLGGTGKDNLTSAT-LPR 311
S P + + + SP+ P S+ +AT LP+
Sbjct: 995 SPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPK 1054
Query: 312 NYKVSPLASDRRSDAGSYRRSL-GSAGPSGTLPRSWQPVSRIPMPPSSPQPRGAPRQRPI 370
+P A+ G SL G+ P P S + P P +P P A P
Sbjct: 1055 GAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSP- 1113
Query: 371 PLSMIFKLQNAFWEH-GA--SRAMLPGSPLFTRA-PPPKLQP------QPQPQ-----PQ 415
K A H GA + A P SP A PPPK P P P+ P
Sbjct: 1114 ------KGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPP 1167
Query: 416 PQSQP--QPQLPPQPQTQPQTPTP--APQHPQQTWP--------PVNEGPPKPPTELEPE 463
P+ P PP P+ TP+P AP P T P P +G P P P
Sbjct: 1168 PKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPS 1227
Query: 464 PEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPALPPEAQSVPELEEVARVLAEIPRPLKR 523
P+ GL TP + P A P SP PP+ P + + P
Sbjct: 1228 PK-GGLATPSPKGAPTT--PAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATP-PH 1283
Query: 524 RGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGG---PEPELSPITEGSEARAGPP 580
+G+ PAV PP+ K + G P P P P+ SP T + PP
Sbjct: 1284 KGAPN--PAVVTPPSPKGGPATSPPK-----GAPTPPAATPPSPKGSPGTPPPKGAPTPP 1336
Query: 581 APAPPAP-----IPPPAPSQSSPPEQPQSME 606
A PP+P +P PS P P S E
Sbjct: 1337 AVTPPSPKGTPTLPATTPSSKGGPTTPSSKE 1367
Score = 84.0 bits (206), Expect = 5e-16
Identities = 152/611 (24%), Positives = 210/611 (34%), Gaps = 109/611 (17%)
Query: 56 PPGPQAGP----PSRPPRYSSSSIPEPFGSRGSP--RKAATDGADTPFGRS--------E 101
PP P+ GP P P +++ P P G +P + A T A TP +
Sbjct: 1087 PPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPK 1146
Query: 102 SAPTLHPYSPLSPKGR------PSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGR 155
APT +P SPKG +P TP P G L +P P+ +
Sbjct: 1147 GAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGL---ATPSPKG--APTTPAAT 1201
Query: 156 APSPRPGPGPLRQQG--------PPTPFDFLGRAGSPRGSPLAEGPQAFFPERGPSPRPP 207
PSP+ G +G PP+P L SP+G+P P+ GP+ PP
Sbjct: 1202 PPSPKGGLATPSPKGAPTTPAATPPSPKGGLATP-SPKGAPTTPAATPPSPKGGPATPPP 1260
Query: 208 ATAYDAPASAFGSSLLGSGGSAFAPPLRAQDDLTLRRRPPKAWNESDLDVAYEKKPSQTA 267
A PA+ S GG A P A + + PK + P+ T
Sbjct: 1261 KGAPTPPAATPPSL---KGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATP 1317
Query: 268 SYERLDVFARPASPSLQLLPWRESSLDGLGGTGKDNLTSATLPRNYKVSPL--ASDRRSD 325
+ P +P + P A P + K +P A+ S
Sbjct: 1318 PSPK----GSPGTPPPKGAP----------------TPPAVTPPSPKGTPTLPATTPSSK 1357
Query: 326 AGSYRRSL--GSAGPSGTLPRSWQPVSRIPMP---PSSPQPRGAPRQRP-IPLSMIFKLQ 379
G S G P+ T P P P P+ P P+G P IPLS
Sbjct: 1358 GGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPA 1417
Query: 380 NAFWEHGASRA----MLPGS--PLFTRAPPPKLQPQPQPQPQPQSQPQPQLPPQPQTQPQ 433
GA+ + P + P+ + P P+ P P S+ P LP P+
Sbjct: 1418 TPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPAT-PSSKGDPTLPAVTPPSPK 1476
Query: 434 TPTPAPQHPQQTWP------PVNEGPPKPPTELEPEPEIEGLLTPVLEAGDVDEGPVARP 487
P Q + P P G P P + P+ E TP + P A
Sbjct: 1477 EPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPK-EVPATPSSRRDPI--APTATL 1533
Query: 488 LS---PTRLQP--ALPPEAQSVPELEEVARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQ 542
LS P L P AL P A +VP ++ + P +P P T+K
Sbjct: 1534 LSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYK-- 1591
Query: 543 YQQIISRLFHRHGGPGPGGPEPELSP-ITEGSEARAG-PPAPAPPAP-----IPPPAPSQ 595
G P P E + P +T S A PPA PP+P P P +
Sbjct: 1592 ------------GAPSP--KELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTP 1637
Query: 596 SSPPEQPQSME 606
+SPP P S++
Sbjct: 1638 TSPPVTPSSLK 1648
Score = 81.6 bits (200), Expect = 3e-15
Identities = 146/614 (23%), Positives = 212/614 (34%), Gaps = 153/614 (24%)
Query: 56 PPGPQAGPPSRPPRYS----SSSIPEPFGSRGSPRKAATDGADTPFGRSESAPTLHPYSP 111
PP P+ GP + PP+ + +++ P P GS G+P + APT +P
Sbjct: 1294 PPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPP-------------KGAPTPPAVTP 1340
Query: 112 LSPKGRPSSPRTPLYLQPDAYGSLDRATS---PRPRAFDGAGSSLGRAPSPRPGPG---P 165
SPKG P+ P T P + G +S P P A PS + GP P
Sbjct: 1341 PSPKGTPTLPATT----PSSKGGPTTPSSKEGPTPPA---------ATPSHKGGPAMTPP 1387
Query: 166 LRQQGPPTPFDFLGRAGSPRGSPLAEGPQAFFPERGPSPRPPATAYDAPASAFGSSLLGS 225
++GP P SP+G P + P++ P+ P T A + G
Sbjct: 1388 SPKRGPAIP--------SPKGDPTSPAVIPLSPKKAPAT--PVTREGAATPSKGD----- 1432
Query: 226 GGSAFAPPLRAQDDLTLRRRP-----------PKAWNESDLDVAYEKKPSQTASYERLDV 274
PP A ++L++ P P + + L P + + +++
Sbjct: 1433 ----LTPP--AVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVAT 1486
Query: 275 FARPASPSLQLLPWRESSLDGLGGTGKDNLTSATLPRNYKVSPLA-SDRRSDAGSYRRSL 333
+ P P +L A +P + K P S RR L
Sbjct: 1487 SSSPKKAPATPAPMGAPTLP------------AVIPSSPKEVPATPSSRRDPIAPTATLL 1534
Query: 334 GSAGPSGTLPRSW--QPVSRIPMP---PSSPQPRGAPRQRPIPLSMIFKLQNAFWEHGAS 388
P+ P+ P +P P P+ P P+ AP P S E +
Sbjct: 1535 SKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPAT---PSSK---------EASSP 1582
Query: 389 RAMLPGSPLFTRAPPPK--LQPQPQPQPQPQSQPQPQL--PPQPQTQPQTPTP--APQHP 442
A+ P + + AP PK L P P P+ P P PP P+ P TP P P P
Sbjct: 1583 PAVTPST--YKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSP 1640
Query: 443 QQTWPPVNEGPPKP-----------PTELEPEPEIEG--LLTPVLEAGDVDEGPVARPLS 489
T + + P P P + P +G L VL A + P+ +
Sbjct: 1641 PVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIIT--A 1698
Query: 490 PTRLQPALPPEAQSVPELEEVARVLAEIPRPLKRRGSMEQ----APAVALPPTHKKQYQQ 545
PTR P + + P + P P + GS APA LP +K +
Sbjct: 1699 PTRKGPQTKKSSATSPPI---------CPDPSAKNGSKGPLSTVAPAPLLPV--QKDSSK 1747
Query: 546 IISRLFHRHGGPGP-GGPEPELS-PITEGS-------------EARAGPPAPAP--PAPI 588
H GP PE + S P+T + A PP P P+P+
Sbjct: 1748 TAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPV 1807
Query: 589 PPPAPSQSSPPEQP 602
P P Q P P
Sbjct: 1808 PTLPPKQQFLPSSP 1821
Score = 72.4 bits (176), Expect = 2e-12
Identities = 144/602 (23%), Positives = 200/602 (33%), Gaps = 102/602 (16%)
Query: 52 DSPAPPGPQAGPPSRPPRYSSSSIPE-PFGSRGSPRKAATDGADTPFGRSESAPTLHPYS 110
D P QA P + P S+SS PE P + K + G P G+ S+ T S
Sbjct: 556 DPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSL-GEPLPIGKPASSMT----S 610
Query: 111 PLSPKGRPSSPRTPLYLQPDAYGSLDRAT--SPRPRAFD-GAGSSLGRAPSPRPGPGPLR 167
PL S +T Y PD+ G L +++ +P AF + G AP+ G
Sbjct: 611 PLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYT 670
Query: 168 QQGPPTPFDFLGRAGSPRGSPLAEGPQAFFP---------ERGPSPR----PPAT---AY 211
P + A P+ P+ EG P PSP+ P AT A
Sbjct: 671 TTASPFLEGTVSLA--PKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAP 728
Query: 212 DAPASAFGSSLLGSG---GSAFAPPLRAQDDLTLRRRPPKAWNESDLDVAYEKKPSQTAS 268
+ P S SL +G G+ + L PK D + T +
Sbjct: 729 EIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLT 788
Query: 269 YERLDVFARPASPSLQLLPWRESSLDGLGGTGKD----NLTSATLPRNYKVSPLASDRRS 324
Y + P+ + + P + G G D NL+S P + S L + S
Sbjct: 789 Y----LADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSP--VEASFLPENSLS 842
Query: 325 DAGSYRRSLGSAGPSGTLPRSWQPVSRIPMPPSSPQPRGA---PRQRPIPLSMIFKLQNA 381
GS + P+ P+ + P + P+G P++ P P +
Sbjct: 843 FQGSKDSPATTHSPTPPSPKG----APTPSAVTPLSPKGVTLPPKETPTPSVVNLP---- 894
Query: 382 FWEHGASRAMLPGSPLF--TRAPPPKLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAP 439
F + G + +P T + P K + P P+ P S P P P +P P
Sbjct: 895 FPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGP 954
Query: 440 QHPQQTWPPV-----------------NEGPPKPPTELEPEPEIEGLLTPVLEAGDVDEG 482
P W P +G P PP P P+ G TP +
Sbjct: 955 ATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPK-GGPATPSPKGAPTP-- 1011
Query: 483 PVARPLSPTRLQPALP-PEAQSVPELEEVARVLAEIPRPLKRRGSMEQAPAVALPPTHKK 541
P P SP A P P+ S P A P P +GS P PT
Sbjct: 1012 PAVTPPSPKGSPAATPFPKGASTPP-------AATPPSP---KGSPAATPLPKGAPT--- 1058
Query: 542 QYQQIISRLFHRHGGPGPGGPEPELSPITEGSEARAGPPAPAPPAPIPPPA-PSQSSPPE 600
P P P+ P T + PPA PP+P PA PS P
Sbjct: 1059 --------------TPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPM 1104
Query: 601 QP 602
P
Sbjct: 1105 PP 1106
Score = 61.6 bits (148), Expect = 3e-09
Identities = 112/483 (23%), Positives = 167/483 (34%), Gaps = 63/483 (13%)
Query: 53 SPAPPGPQAGPPSRPPRYSSSSIPEPFGSRGSPRKAATDGADTPFGRSESAPTLHPYSPL 112
+P+ G P PP P+ + SP+KA A P G APTL P
Sbjct: 1458 TPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPA--PMG----APTLPAVIPS 1511
Query: 113 SPK---GRPSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRAPSPRPGPG-PLRQ 168
SPK PSS R P+ AT A ++ PSP+ P P +
Sbjct: 1512 SPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTV---PSPKKTPAIPTPK 1568
Query: 169 QGPPTPFDFLGRA----------GSPRGSPLAEGPQAFFPERGPSPRPPATAYDAPASAF 218
+ P TP + G+P L P P +P PPA +P
Sbjct: 1569 EAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEK-- 1626
Query: 219 GSSLLGSGGSAFAPPLRAQDDLTLRRRPPKAWNESDLDVAYEKK--PSQTASYERLDVFA 276
G + G+ +PP+ P + V K P++ +V
Sbjct: 1627 GPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLV 1686
Query: 277 RPASPSLQLL--PWRESSLDGLGGTGKDNLTSATLPRNYKVSPLASDRRSDAGSYRRSLG 334
PA S ++ P R+ + +SAT P P+ D + GS + L
Sbjct: 1687 APAPESTPIITAPTRKGP--------QTKKSSATSP------PICPDPSAKNGS-KGPLS 1731
Query: 335 SAGPSGTLPRSWQPVSRIPMPPSSPQPRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLPG 394
+ P+ LP +S P+G P L A +E + P
Sbjct: 1732 TVAPAPLLPVQKDSSKTAKGKDASHSPKGP--LAPPESKASTPLTAAAFEKVLPK---PE 1786
Query: 395 SPLFTRAPPPKLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPPVNEG-- 452
S + AP P + P P P LPP+ Q P +P + P + P +E
Sbjct: 1787 SASVSAAPSPPVSLPLAPSPVPT------LPPKQQFLPSSPGLVLESPSKPLAPADEDEL 1840
Query: 453 ----PPKPPTELEP-EPEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPALPPEA-QSVPE 506
PP+P + P + + + TP V +P++ ++ +SVPE
Sbjct: 1841 LPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPE 1900
Query: 507 LEE 509
LEE
Sbjct: 1901 LEE 1903
Score = 36.6 bits (83), Expect = 0.098
Identities = 77/301 (25%), Positives = 104/301 (34%), Gaps = 40/301 (13%)
Query: 333 LGSAGPSGTLPRSWQPVSRIPMPPSSPQPRG----APRQRPIPLSMIFKLQNAFWEHGAS 388
L SA P+G P + + S +SP G AP+ P+ + L +
Sbjct: 650 LESADPAGVAPTTAKGTSTYTTT-ASPFLEGTVSLAPKNHPVKEGTLTTLPLV--PTASE 706
Query: 389 RAMLPGSPLFTRAPPPKLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPP 448
+ SP T AP L P+ P+S P P LPP T P T P
Sbjct: 707 NCPVAPSPQNTCAPLATLVLAPEI---PKSVPSPSLPPAG-TPPGTKKVDGISHTSALAP 762
Query: 449 VNEGPPKPPTE---LEPEPEIEGLLTPVLEAGD---VDEGPVAR--PLSPTRLQPALPPE 500
V P + PTE +G LT + ++ V P + P P P
Sbjct: 763 VASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIG 822
Query: 501 AQSVPELEEVARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPG 560
S P A L E L +GS + +PA PT G P P
Sbjct: 823 NLSSPVSPVEASFLPE--NSLSFQGSKD-SPATTHSPTPPSP-----------KGAPTPS 868
Query: 561 GPEPELSPITEGSEARAGPPAPAPPAPIPPPAPSQSSPPEQPQSMEMRSVLRKAGSPRKA 620
P LSP + P P P P+ +P + P ++ M S SP+KA
Sbjct: 869 AVTP-LSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAP-ALSMTS-----SSPKKA 921
Query: 621 R 621
R
Sbjct: 922 R 922
Score = 31.6 bits (70), Expect = 3.2
Identities = 42/208 (20%), Positives = 66/208 (31%), Gaps = 26/208 (12%)
Query: 409 QPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQT-----WPPVNEGPPKPPTELEPE 463
QP P P P PQ P +P P+P T +P + G P L
Sbjct: 40 QPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALP---LGTA 96
Query: 464 PEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPALPPEAQSVPELEEVARVLAEIPRPLKR 523
PE L ++ GP P + P + P + P ++A P +++
Sbjct: 97 PEAPTFLPNLI-------GPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQK 149
Query: 524 RGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPEL----SPITEGSEARAGP 579
+ + P + +I+ P P+ L S + + P
Sbjct: 150 SSAFPPNLLTSPPSVAVAESGSVIT----LSAPIAPSEPKTNLNKVPSEVVPNPKGTPSP 205
Query: 580 PAPAPPAP---IPPPAPSQSSPPEQPQS 604
P P + P A QS PQ+
Sbjct: 206 PCIVSTVPYHCVTPMASIQSGVASLPQT 233
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 102 bits (255), Expect = 1e-21
Identities = 165/615 (26%), Positives = 217/615 (35%), Gaps = 82/615 (13%)
Query: 54 PAP-PGPQAGPPSRPPRYSSSSIPEPFGSRGSP----RKAATDGADTPFGRSESAPTLHP 108
P P P + PP+ PR S SS E + SP R +A G P RS S+
Sbjct: 190 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL 249
Query: 109 YSPL----SPKGRPSSPRTPLYLQPDAYGSL--DRATSPRPRAFDGAGSSLGRAPSPRPG 162
SP S +G P +P P +P +L + T PR A G L +P P
Sbjct: 250 SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP-LSSSPLATPS 308
Query: 163 PGPLRQQGPP------TPFDFLGRAGSPRGSPLAEGPQAFFPERGPS----PRPPATA-Y 211
P + + P TP P +PL P + P PS P PPAT
Sbjct: 309 PSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPS--PSAPPSLQTLPSPPATPPS 366
Query: 212 DAPASAFGSSLLGSGGSAFAPPLRAQDDLTLR--RRPPKAWNESDLDVAYEK-KPSQTAS 268
AP S + PP++ LT + PP S L P+ A+
Sbjct: 367 QAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQAT 426
Query: 269 YERLDVFARPASPSLQLLPWRESSLDGLGGTGKDNLTSATLPR-----NYKVSPLASDRR 323
+ L + R SL P R +S + L+ P + VSPL+S
Sbjct: 427 HSFLTMSPRQTQASLTS-PSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLT 485
Query: 324 SDAGSYRRSLGSAGPSGTLPRSWQPVSRIPMPPSSPQPRGAPRQRPIPLSMIFK--LQNA 381
SL S P P+S + MPP Q AP P + + L+N
Sbjct: 486 IHPLQALSSLASHSPQA-------PLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENL 538
Query: 382 FWEHGASRAMLPGSPLFTRAPP---PKLQPQPQPQPQP-QSQPQPQLPPQPQTQPQTPTP 437
L PL T + P P L+ P P P P Q+ P P P P+T TP
Sbjct: 539 --------PSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATP 590
Query: 438 APQHPQQTWPPVNEGPPKPPTE--LEPEPEIEGLLT-PVLEAGDVDEGPVARPLSPTRLQ 494
PQ P P +G P PP P P+ L P L+A P + PLSP
Sbjct: 591 PPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPP--SPPASPPLSPLATP 648
Query: 495 PALPPEAQSVPELEEVARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRH 554
P A +V L+ A P++ S +P V+ T Q
Sbjct: 649 SPQAPNALAVHLLQ--APFSPPPSPPVQAPFSPPASPPVSPSATPPSQ------------ 694
Query: 555 GGPGPGGPEPELSPITEGSEARAGPPAPAPPAPIPPPAPSQSSPPEQPQSMEMRSVLRKA 614
P P ++ P S + P P AP P AP PP P S M
Sbjct: 695 APPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPM------- 747
Query: 615 GSPRKARRARLNPLV 629
SP R+ PL+
Sbjct: 748 -SPSATPPPRVPPLL 761
Score = 87.8 bits (216), Expect = 4e-17
Identities = 157/645 (24%), Positives = 211/645 (32%), Gaps = 124/645 (19%)
Query: 44 KQLESLWSDSPAPPGPQAGPPSRPPRYSSSSIPEPFGSRGSPRKAATDGADTPFGRSESA 103
K L++L PP A P P S + P P G++ P D A TP
Sbjct: 275 KGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARP-VPPPDNAATPL-----P 328
Query: 104 PTLHPYSPLSPKG--RPSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRAPSPRP 161
TL P PL+ P SP P LQ T P P A + + P
Sbjct: 329 ATLPPSPPLATPLPLAPPSPSAPPSLQ----------TLPSPPATPPSQAPPSMTTPPMQ 378
Query: 162 GPGPLRQ---------------QGPPTPFDFLG-RAGSPRGSPLAEGPQAFF-------- 197
P L+ Q PP+P +A + GSP + +F
Sbjct: 379 APPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQ 438
Query: 198 -----PERGPSPRPPATAYDAPASAFGSSLLGSGGSAFAPPLRAQDDLTLRRRPPKAWNE 252
P R S P + AP S S L + S PL + L P +A
Sbjct: 439 ASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSP----LTIHPLQAL-- 492
Query: 253 SDLDVAYEKKPSQTASYERLDVFARPASPSLQLLPWRESS--LDGLGGTGKDNLTSATLP 310
S L + P + L+ + A PSLQ P ++ L+ L L +A+ P
Sbjct: 493 SSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAP 552
Query: 311 RNYK----------------VSPLASDRRSDAGSYRRSLGSAGPSGTLPRSWQPVSRIPM 354
SPL + S A P+ P P+ +P
Sbjct: 553 LTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASP----PLQGLPS 608
Query: 355 PPSSPQPRGAPRQRPI----------------PLSMIF----KLQNAFWEHGASRAMLPG 394
PP SP P+ P PLS + + NA H P
Sbjct: 609 PPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 668
Query: 395 SPLFTRAP-PPKLQPQPQPQPQPQSQPQP-------QLPPQPQTQP---QTPTPAPQHPQ 443
+AP P P P P SQ P Q+PP P P + TP PQ P
Sbjct: 669 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP 728
Query: 444 QTWPPVNEGPPKPPT------ELEPEPEIEGLL-TPVLEAGDVDEGPVARPLSPTRLQPA 496
P + PP PP P P + LL P L+ P + P+SP P
Sbjct: 729 PLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQV--PPSPPASLPMSPLAKPPP 786
Query: 497 LPPEAQSVPELEEVARVLAEIP--RPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRH 554
P A + P L+ + A P P S+ +P PP Q +++ +
Sbjct: 787 QAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPP----QAPPVLAAPLLQV 842
Query: 555 GGPGPGGP---EPELSPITEGSEARAGPPAPAPPAPIPPPAPSQS 596
P P P P + +GP AP PPP PS+S
Sbjct: 843 PPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRS 887
Score = 86.7 bits (213), Expect = 8e-17
Identities = 158/637 (24%), Positives = 214/637 (33%), Gaps = 136/637 (21%)
Query: 53 SPAPPG-PQAGPPSRPPRYSSSSIPEPFGSRG-SPRKAATDGADTPFGRSESAPTLHPYS 110
+P PPG P+ PP P G + + R GA P ESAP P
Sbjct: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP----ESAPRAGPTR 81
Query: 111 PLSPKGRPSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRAPSPRPGPGPLRQQG 170
R + R P A G +RA P G SS GRA S PGPL Q+G
Sbjct: 82 SAGTSSRNPASRPP------ASGRGERAP-PAKNTSPGPVSSPGRA-SGTTRPGPLGQKG 133
Query: 171 PPTPFDFLGRAG----SPRGSPLAEGPQAFFPERGPSPRPPATAYDAPASAFGSSLLGSG 226
+ G +P+ S L+ G + GP+P P+ A + A G+ + G
Sbjct: 134 LRISAEETVARGKATEAPKRSALSAGARR--DTSGPTPGTPSPAMARRSRAAGTEV---G 188
Query: 227 GSAFAPPLRAQDDLTLRRRPPKAWNESDLDVAYEKKPSQTASYERLDVFA-----RPASP 281
AP + R RPP + A E ++ + R A RPAS
Sbjct: 189 LPRPAP--------SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 240
Query: 282 SLQLLPWRESSLDGLGGTGKDNLTSATLPRNYK-----------VSPLASDRRSDAGSYR 330
SL SS G + + + P K V+P D G
Sbjct: 241 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS 300
Query: 331 RS-LGSAGPSGTLPRSWQPVSRIPMPPSSPQPRGAPRQRPIPLSMIFKLQNAFWEHGASR 389
S L + PSGT R P P + P P P+PL+
Sbjct: 301 SSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLA---------------- 344
Query: 390 AMLPGSPLFTRAPPPKLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAP--QHPQQTWP 447
P SP + PP LQ P P P SQ P + P P + P Q P
Sbjct: 345 ---PPSP----SAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTS 397
Query: 448 PVNEGPPKP--------------PT--------ELEPEPEIEGLLTPVLEAGDVDEGP-- 483
P + PP P PT + P L +P A + P
Sbjct: 398 PSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPL 457
Query: 484 ---VARPLSP---TRLQPALPPEAQ--SVPELEEVARVLAEIPR---------PLKRRGS 526
++ P SP T L PA+ P + ++ L+ ++ + + P+ PL+ + S
Sbjct: 458 QAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSS 517
Query: 527 M-----------------EQAPAVALPPTHKKQYQQIISRLFHRHGGPGP----GGPEPE 565
+ E P++A PP L P P P P
Sbjct: 518 LAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHL-ETPPCPAPCPLQAPPSPL 576
Query: 566 LSPITEGSEARAGPPAPAPPAPIPPPAPSQSSPPEQP 602
+P E + A PP APPA PP SPP P
Sbjct: 577 TTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSP 613
Score = 82.0 bits (201), Expect = 2e-15
Identities = 150/627 (23%), Positives = 206/627 (32%), Gaps = 102/627 (16%)
Query: 55 APPGPQAGPPSRPPRYSSSSIPEPFGSRGSPRKAATDGADTPFGRSESAPTLHPYSPLSP 114
+P P + PP PP + S+P P + + A +P S T+HP LS
Sbjct: 443 SPSRPASTPPDSPPLQAPLSLPA-----SPPLQTSLSPAVSPLS---SPLTIHPLQALSS 494
Query: 115 KGR--PSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRAPS---PRPGPGPLRQQ 169
P +P + L + P L+ +S P + +SL P P P PL+
Sbjct: 495 LASHSPQAPLSSLIMPP-----LETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTA 549
Query: 170 GPPTPFDFLGRAGSPRGSPLAEGPQAFF---PERG-----PSPRPPATAYDAPASAFGSS 221
P L P PL P PE P P+ P P S
Sbjct: 550 SAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSP 609
Query: 222 LLGSGGSA--FAPPLRAQDDLTLRRRPPKAWNESDLDVAYEKKPSQTASYERLDVFARPA 279
L + APP A L PP + S L + P+ A + F+ P
Sbjct: 610 PLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP 669
Query: 280 SPSLQLLPWRESSLDGLGGTGKDNLTSATLPRNYKVSPLASDRRSDAGSYRRSLGSAGPS 339
SP +Q P+ + + + + P + PL A + P
Sbjct: 670 SPPVQA-PFSPPASPPVSPSATP---PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 725
Query: 340 GTLPRSWQPVSRIPMPPSSP--QPRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLPGSPL 397
P + P+ P PP+SP P P R PL LQ + A LP SPL
Sbjct: 726 APPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVP----PSPPASLPMSPL 781
Query: 398 FT---RAPPPKLQPQPQPQPQPQSQPQPQLPPQPQTQ-PQTP--TPAPQHPQQTWPPVNE 451
+APP P Q P P + Q P P P +P TP PQ P P+ +
Sbjct: 782 AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQ 841
Query: 452 GPPKPPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPALPPEAQ-------SV 504
PP PP P ++ P D V+ P L P PP S
Sbjct: 842 VPPSPPAS----PTLQAPRRPPTPGPDTS---VSGPRLTLALAPGPPPPPSRSPSSTLSG 894
Query: 505 PELEEVARVLAEIPRPLKRRGSMEQAPAVALPPT-------HKKQYQQIISRLFHRHGGP 557
P+L + P L+ S + A A PP H + + + G P
Sbjct: 895 PDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAP 954
Query: 558 G--------------------------------PGGPEPELSPITEGSEARAGPPAPAPP 585
G PG +P SP T G +A AG A A
Sbjct: 955 GAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASS 1014
Query: 586 APIPPPAPSQSSPPEQPQSMEMRSVLR 612
+P Q+ E P SV++
Sbjct: 1015 R-----SPKQARLGELPLGALQASVVQ 1036
Score = 63.9 bits (154), Expect = 6e-10
Identities = 123/495 (24%), Positives = 178/495 (35%), Gaps = 81/495 (16%)
Query: 180 RAGSPRGSPLAEGPQAFFPERGPSPRPPATAYDAPASAFGSSLLGSGGSAFAPPLRAQ-- 237
+AG+ +P A P P SPRPP P + +LG+ G+ PL +
Sbjct: 9 KAGAAARTPAARAPGLLTPRPPGSPRPP-----PPVTPAALRVLGAAGAVGRKPLAERAG 63
Query: 238 -------DDLTLRRRPPKAWNESDLDVAYEKKPSQTASYERLDVFARPASPSLQLLPWRE 290
+ R P ++ S + A +P + ER A+ SP P R
Sbjct: 64 GIGGATIPESAPRAGPTRSAGTSSRNPA--SRPPASGRGERAPP-AKNTSPGPVSSPGRA 120
Query: 291 SSLDGLGGTGKDNL---TSATLPRNY-----KVSPLASDRRSDAG---------SYRRSL 333
S G G+ L T+ R K S L++ R D + R
Sbjct: 121 SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS 180
Query: 334 GSAGPSGTLPRSWQPVSRIPMPP--------------SSPQPRGAPRQRPI--------- 370
+AG LPR P +R P PP S+ +P A R+RP
Sbjct: 181 RAAGTEVGLPRP-APSAR-PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPA 238
Query: 371 --PLSMIFKLQNAFWEHGASRAMLPGSPLFTRAPPPK-LQPQPQPQ-PQPQSQPQPQLPP 426
LS ++ G S P +P P PK LQ PQ P+ P L P
Sbjct: 239 SRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP 298
Query: 427 QPQTQPQTPTPAPQHPQQTWPPVNEGPPKPPTELEPEPEIEGLLTPVLEAGDVDEGPVAR 486
+ TP+P+ + PP N P P T L P P L TP+ A P A
Sbjct: 299 LSSSPLATPSPSGTKARPVPPPDNAATPLPAT-LPPSPP---LATPLPLA---PPSPSAP 351
Query: 487 PLSPTRLQPALPPEAQSVPELE----EVARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQ 542
P T P P +Q+ P + + L IP P++ S+ +P++ PP+
Sbjct: 352 PSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIP-PIQVPHSL-TSPSLQAPPS---- 405
Query: 543 YQQIISRLFHRHGGPGPGGPEPELSPITEGSEARAGPPAPAPPAPIPPPAPSQSSPPEQP 602
+S L P + +A +P+ PA PP +P +P P
Sbjct: 406 -PLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLP 464
Query: 603 QSMEMRSVLRKAGSP 617
S +++ L A SP
Sbjct: 465 ASPPLQTSLSPAVSP 479
Score = 41.2 bits (95), Expect = 0.004
Identities = 81/343 (23%), Positives = 119/343 (34%), Gaps = 74/343 (21%)
Query: 330 RRSLGSAGPSGTLPRSWQPVSRIPMPPSSPQPRGAPRQRPIPLSMIFKLQNAFWEHGASR 389
+R AG + P + P P PP SP+P P P L ++ GA+
Sbjct: 4 KRDKAKAGAAARTPAARAPGLLTPRPPGSPRP--PPPVTPAALRVL----------GAAG 51
Query: 390 AMLPGSPLFTRAPPPKLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPPV 449
A + PL RA + P+ P++ P ++ + ++P P
Sbjct: 52 A-VGRKPLAERA--GGIGGATIPESAPRAGP-----------TRSAGTSSRNPASRPPAS 97
Query: 450 NEGPPKPPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPALPPEAQSVPELEE 509
G PP A + GPV+ SP R P P ++
Sbjct: 98 GRGERAPP------------------AKNTSPGPVS---SPGRASGTTRPG----PLGQK 132
Query: 510 VARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPELSPI 569
R+ AE RG +AP + + + GP PG P P ++
Sbjct: 133 GLRISAE---ETVARGKATEAP----------KRSALSAGARRDTSGPTPGTPSPAMARR 179
Query: 570 TEGSEARAGPPAPAPPA-PIPP---PAPSQSSPPE----QPQSMEMRSVLRKAGSPRKAR 621
+ + G P PAP A P PP P S SS E +P R G R A
Sbjct: 180 SRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPAS 239
Query: 622 RARLNPLVLLLDAALTGELEVVQQAVKEMNDPSQPNEEGITAL 664
R+ + L A +G + + PSQP +G+ AL
Sbjct: 240 RSLSSSATPLSSPARSG--PSARGTPRAPAHPSQPKPKGLQAL 280
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 94.4 bits (233), Expect = 4e-19
Identities = 156/604 (25%), Positives = 213/604 (35%), Gaps = 71/604 (11%)
Query: 54 PAP-PGPQAGPPSRPPRYSSSSIPEPFGSRGSP----RKAATDGADTPFGRSESAPTLHP 108
P P P + PP+ PR S SS E + SP R +A G P RS S+
Sbjct: 190 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL 249
Query: 109 YSPL----SPKGRPSSPRTPLYLQPDAYGSL--DRATSPRPRAFDGAGSSLGRAPSPRPG 162
SP S +G P +P P +P +L + T PR A G L +P P
Sbjct: 250 SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP-LSSSPLATPS 308
Query: 163 PGP-LRQQGPPT----PFDFLGRAGSPRGSPLAEGPQAFFPERGPSPRPPATAYDAPASA 217
P L+ Q PPT P PLA + P P PPAT ++
Sbjct: 309 PSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTS 368
Query: 218 FGSSLLGSGGSAF--------------APPLRAQDDLTLRRRPPKAWNESDLDVAYEKKP 263
GS L + S APP A L PP + S L + P
Sbjct: 369 LGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAP 428
Query: 264 SQTASYERLDVFARPASPSLQLLPWRESSLDGLGGTGKDNLTSATLPRNYKVSPLASDRR 323
+ A + F+ P SP +Q P+ + + + + P + PL
Sbjct: 429 NALAVHLLQAPFSPPPSPPVQA-PFSPPASPPVSPSATP---PSQAPPSLAAPPLQVPPS 484
Query: 324 SDAGSYRRSLGSAGPSGTLPRSWQPVSRIPMPPSSPQPRGAPRQRPIPLSMI-FKLQNAF 382
A + P P + P+ PP +P P + +P F Q F
Sbjct: 485 PPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPF 544
Query: 383 WEHGASRAMLPGSPLFT---RAPPPKLQPQPQPQPQPQSQPQPQLPPQPQTQ-PQTPTPA 438
+ A LP SPL T +APP P Q P P + P Q P +P T P T
Sbjct: 545 ----SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG 600
Query: 439 PQHPQQTWPPVNEGPPKPPTELEPE----PEIEGLLTPVLEAGDVDEGPVARPLSPTRLQ 494
P+ P GPP PP+ P++ G + + G + P
Sbjct: 601 PRLTLALAP----GPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAAS 656
Query: 495 PALPPEAQSVPELEEVARVLAEIPRPLKRRGSMEQAPAVALP--PTHKKQYQQIISRLFH 552
P PP+A+ + A P PL RG AP LP P + ++
Sbjct: 657 P--PPDAE-LAACHPAAWSRGPAP-PLAFRG----APGAPLPWPPATGPGSADGLCTIYE 708
Query: 553 RHGG----PGPGGPEPELSPITEGSEARAGPPAPAPPAPIPPPAPSQSSPPEQPQSMEMR 608
G P PG +P SP T G +A AG A A +P Q+ E P
Sbjct: 709 TEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSR-----SPKQARLGELPLGALQA 763
Query: 609 SVLR 612
SV++
Sbjct: 764 SVVQ 767
Score = 91.3 bits (225), Expect = 3e-18
Identities = 154/600 (25%), Positives = 213/600 (35%), Gaps = 124/600 (20%)
Query: 53 SPAPPG-PQAGPPSRPPRYSSSSIPEPFGSRG-SPRKAATDGADTPFGRSESAPTLHPYS 110
+P PPG P+ PP P G + + R GA P ESAP P
Sbjct: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP----ESAPRAGPTR 81
Query: 111 PLSPKGRPSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRAPSPRPGPGPLRQQG 170
R + R P A G +RA P G SS GRA S PGPL Q+G
Sbjct: 82 SAGTSSRNPASRPP------ASGRGERAP-PAKNTSPGPVSSPGRA-SGTTRPGPLGQKG 133
Query: 171 PPTPFDFLGRAG----SPRGSPLAEGPQAFFPERGPSPRPPATAYDAPASAFGSSLLGSG 226
+ G +P+ S L+ G + GP+P P+ A + A G+ + G
Sbjct: 134 LRISAEETVARGKATEAPKRSALSAGARR--DTSGPTPGTPSPAMARRSRAAGTEV---G 188
Query: 227 GSAFAPPLRAQDDLTLRRRPPKAWNESDLDVAYEKKPSQTASYERLDVFARPASPSLQLL 286
AP + R RPP + A E ++ + R
Sbjct: 189 LPRPAP--------SARPRPPTEGPRKSVSSASEHSTTEPSPAARR-------------- 226
Query: 287 PWRESSLDGLGGTGKDNLTSATLPRNYKVSPLASDRRSDAGSYRRSLGSAGPSGTLPRSW 346
R S+ GL +L+S+ +PL+S RS GPS
Sbjct: 227 --RPSAGGGLQRPASRSLSSSA-------TPLSSPARS------------GPSA------ 259
Query: 347 QPVSRIPMPPSSPQPRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLPGSPLFTRAPPPKL 406
+ R P PS P+P+G RP ++ K + + L SPL T +P L
Sbjct: 260 RGTPRAPAHPSQPKPKGLQALRPPQVTPPRK------DAAPALGPLSSSPLATPSPSAAL 313
Query: 407 QPQPQPQ----------------PQPQSQPQPQLPPQPQTQPQTP-TPAPQHPQQTWPPV 449
Q Q P P P + P P PP QT P P TP P Q +
Sbjct: 314 QSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATP----PSQATTSL 369
Query: 450 NEGPPKPPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPALPPEAQSVPELEE 509
+ P P + L TP +A P A L P + PP + P L
Sbjct: 370 GSPTLQATHSFLPSPPLSPLATPPPQA------PPALALPPLQA----PPSPPASPPLSP 419
Query: 510 VARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPELSPI 569
+A + P L + QAP + PP+ Q P P +P
Sbjct: 420 LATPSPQAPNALAVH--LLQAP-FSPPPSPPVQAP---------FSPPASPPVSPSATPP 467
Query: 570 TEGSEARAGPPAPAPPAP--IPPPAPSQSSPPEQPQSMEMRSVLRKAGSPRKARRARLNP 627
++ + A PP PP+P PP +PS + PP+ P + L+ A P +A A P
Sbjct: 468 SQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPL-AAPPLQLAKPPPQAPPALATP 526
Score = 76.6 bits (187), Expect = 9e-14
Identities = 156/595 (26%), Positives = 201/595 (33%), Gaps = 132/595 (22%)
Query: 55 APPGPQA--GPPSRPPRYSSSSIPEPFGSRG----------------SPRKAATDGADTP 96
APP GP S P R S ++ P P G +G +P+++A
Sbjct: 103 APPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGAR- 161
Query: 97 FGRSESAPTLHPYSPLSPKGRPSSPRTPLYLQPDAYGSLDRATSPRPR-AFDGAGSSLGR 155
R S PT SP + R + T + L A + R + PR + A
Sbjct: 162 --RDTSGPTPGTPSPAMAR-RSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTT 218
Query: 156 APSPRPGPGPLRQQGPPTPFD-FLGRAGSPRGSPLAEGPQAFFPERGPSP---------- 204
PSP P G P L + +P SP GP A R P+
Sbjct: 219 EPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQ 278
Query: 205 --RPPATAYDAPASAFGSSLLGSGGSAFAPP---LRAQDDLTLRRRPPKAWNESDLDVAY 259
RPP +A L S A P L++Q TL P + L
Sbjct: 279 ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPL 338
Query: 260 EKKPSQTASYERLDVFARPASPSLQLLPWRESSLDGLGGTGKDNLTSATLPRNYK----- 314
P + A PSLQ LP ++ T +L S TL +
Sbjct: 339 PLAPPSPS-----------APPSLQTLPSPPATPPSQATT---SLGSPTLQATHSFLPSP 384
Query: 315 -VSPLASDRRSDAGSYRRSLGSAGPSGTLPRSWQPVSRIPMPPSSPQPRGAPRQRPIPLS 373
+SPLA+ A P+ LP P+ P PP+SP +P P P
Sbjct: 385 PLSPLATPPPQ-----------APPALALP----PLQAPPSPPASPPL--SPLATPSP-- 425
Query: 374 MIFKLQNAFWEHGASRAMLPGSPLFTRAP-PPKLQPQPQPQPQPQSQPQPQLPPQP-QTQ 431
+ NA H P +AP P P P P SQ P L P Q
Sbjct: 426 ---QAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP 482
Query: 432 PQTPTPAPQHPQQTWPPVNEGPP---KPPTEL-EPEPEI-EGLLTPVLEA--GDVDEGPV 484
P P P P T PP + PP PP +L +P P+ L TP L+A P
Sbjct: 483 PSPPASPPMSPSATPPP--QAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPG 540
Query: 485 ARPLSPTRLQPALP---PEAQSVPELEEVARVLAEIPRPLKRRGSMEQAPAVALPPTHKK 541
P SP+ P P P Q+ P L A L ++P P QAP PPT
Sbjct: 541 QAPFSPSASLPMSPLATPPPQAPPVL---AAPLLQVP-PSPPASPTLQAP--RRPPT--- 591
Query: 542 QYQQIISRLFHRHGGPGPGGPEPELSPITEGSEARAGPPAPAPPAPIPPPAPSQS 596
PGP + +GP AP PPP PS+S
Sbjct: 592 ---------------PGP-------------DTSVSGPRLTLALAPGPPPPPSRS 618
Score = 41.2 bits (95), Expect = 0.004
Identities = 81/343 (23%), Positives = 119/343 (34%), Gaps = 74/343 (21%)
Query: 330 RRSLGSAGPSGTLPRSWQPVSRIPMPPSSPQPRGAPRQRPIPLSMIFKLQNAFWEHGASR 389
+R AG + P + P P PP SP+P P P L ++ GA+
Sbjct: 4 KRDKAKAGAAARTPAARAPGLLTPRPPGSPRP--PPPVTPAALRVL----------GAAG 51
Query: 390 AMLPGSPLFTRAPPPKLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPPV 449
A + PL RA + P+ P++ P ++ + ++P P
Sbjct: 52 A-VGRKPLAERA--GGIGGATIPESAPRAGP-----------TRSAGTSSRNPASRPPAS 97
Query: 450 NEGPPKPPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPALPPEAQSVPELEE 509
G PP A + GPV+ SP R P P ++
Sbjct: 98 GRGERAPP------------------AKNTSPGPVS---SPGRASGTTRPG----PLGQK 132
Query: 510 VARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPELSPI 569
R+ AE RG +AP + + + GP PG P P ++
Sbjct: 133 GLRISAE---ETVARGKATEAP----------KRSALSAGARRDTSGPTPGTPSPAMARR 179
Query: 570 TEGSEARAGPPAPAPPA-PIPP---PAPSQSSPPE----QPQSMEMRSVLRKAGSPRKAR 621
+ + G P PAP A P PP P S SS E +P R G R A
Sbjct: 180 SRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPAS 239
Query: 622 RARLNPLVLLLDAALTGELEVVQQAVKEMNDPSQPNEEGITAL 664
R+ + L A +G + + PSQP +G+ AL
Sbjct: 240 RSLSSSATPLSSPARSG--PSARGTPRAPAHPSQPKPKGLQAL 280
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 93.6 bits (231), Expect = 7e-19
Identities = 142/581 (24%), Positives = 201/581 (34%), Gaps = 78/581 (13%)
Query: 53 SPAPPG-PQAGPPSRPPRYSSSSIPEPFGSRG-SPRKAATDGADTPFGRSESAPTLHPYS 110
+P PPG P+ PP P G + + R GA P + PT
Sbjct: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85
Query: 111 PLSPKGRPSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRAPSPRPGPGPLRQQG 170
P S +G + P + TSP P + G S R PGPL Q+G
Sbjct: 86 PASGRGERAPPA--------------KNTSPGPVSSPGRASGTTR-------PGPLGQKG 124
Query: 171 PPTPFDFLGRAG----SPRGSPLAEGPQAFFPERGPSPRPPATAYDAPASAFGSSLLGSG 226
+ G +P+ S L+ G + GP+P P+ A + A G+ + G
Sbjct: 125 LRISAEETVARGKATEAPKRSALSAGARR--DTSGPTPGTPSPAMARRSRAAGTEV---G 179
Query: 227 GSAFAPPLRAQDDLTLRRRPPKAWNESDLDVAYEKKPSQTASYERLDVFA-----RPASP 281
AP + R RPP + A E ++ + R A RPAS
Sbjct: 180 LPRPAP--------SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 231
Query: 282 SLQLLPWRESSLDGLGGTGKDNLTSATLPRNYKVSPLASDRRSDAGSYRRSLGSA-GPSG 340
SL SS G + + + P K L + R R+ A GP
Sbjct: 232 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS 291
Query: 341 TLPRSWQPVSRIPMPPSSPQPRGAPRQRPIPLSMIFKLQNAFWEHG-----ASRAMLPGS 395
+ P + P P + P P P + +P A G A+ + LP
Sbjct: 292 SSPLA------TPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSP 345
Query: 396 PLFTRAPPPKLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPPVNEGPPK 455
PL A PP P P Q+ P P P P P TP+PQ P + + P
Sbjct: 346 PLSPLATPPPQAPPALALPPLQAPPSP--PASPPLSPLA-TPSPQAPNALAVHLLQAPFS 402
Query: 456 PPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPALPPEAQSVPELEEVARVLA 515
PP P P ++ +P P + P+SP+ P+ P + + P L+ A
Sbjct: 403 PP----PSPPVQAPFSP----------PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA 448
Query: 516 EIPRPLKRRGSMEQAPAVALPPTH-KKQYQQIISRLFHR--HGGPGPGGPEPELSPITEG 572
P + P +A PP K Q L P P P +P +
Sbjct: 449 SPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPS 508
Query: 573 SEARAGPPAPAPP-APIPPPAPSQSSPPEQPQSMEMRSVLR 612
+ P A PP AP AP PP P S +++ R
Sbjct: 509 ASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRR 549
Score = 91.7 bits (226), Expect = 3e-18
Identities = 153/592 (25%), Positives = 209/592 (35%), Gaps = 77/592 (13%)
Query: 54 PAP-PGPQAGPPSRPPRYSSSSIPEPFGSRGSP----RKAATDGADTPFGRSESAPTLHP 108
P P P + PP+ PR S SS E + SP R +A G P RS S+
Sbjct: 181 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL 240
Query: 109 YSPL----SPKGRPSSPRTPLYLQPDAYGSL--DRATSPRPRAFDGAG---SSLGRAPSP 159
SP S +G P +P P +P +L + T PR A G SS PSP
Sbjct: 241 SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP 300
Query: 160 RPGPGPLR----QQGPPTPFDFLGRAGSPRGSPLAEGPQAFFPERGPSPRPPATAYDAPA 215
P P Q P P +A + GSP + +F P SP PA
Sbjct: 301 SAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPA 360
Query: 216 SAFGSSLLGSGGSAFAPPLRAQDDLTLRRRPPKAWNESDLDVAYEKKPSQTASYERLDVF 275
A PPL+A PP + S L + P+ A + F
Sbjct: 361 LAL-------------PPLQAPPS------PPASPPLSPLATPSPQAPNALAVHLLQAPF 401
Query: 276 ARPASPSLQLLPWRESSLDGLGGTGKDNLTSATLPRNYKVSPLASDRRSDAGSYRRSLGS 335
+ P SP +Q P+ + + + + P + PL A +
Sbjct: 402 SPPPSPPVQA-PFSPPASPPVSPSATP---PSQAPPSLAAPPLQVPPSPPASPPMSPSAT 457
Query: 336 AGPSGTLPRSWQPVSRIPMPPSSPQPRGAPRQRPIPLSMI-FKLQNAFWEHGASRAMLPG 394
P P + P+ PP +P P + +P F Q F + A LP
Sbjct: 458 PPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPF----SPSASLPM 513
Query: 395 SPLFT---RAPPPKLQPQPQPQPQPQSQPQPQLPPQPQTQ-PQTPTPAPQHPQQTWPPVN 450
SPL T +APP P Q P P + P Q P +P T P T P+ P
Sbjct: 514 SPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP--- 570
Query: 451 EGPPKPPTELEPE----PEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPALPPEAQSVPE 506
GPP PP+ P++ G + + G + P P PP+A+ +
Sbjct: 571 -GPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASP--PPDAE-LAA 626
Query: 507 LEEVARVLAEIPRPLKRRGSMEQAPAVALP--PTHKKQYQQIISRLFHRHGG----PGPG 560
A P PL RG AP LP P + ++ G P PG
Sbjct: 627 CHPAAWSRGPAP-PLAFRG----APGAPLPWPPATGPGSADGLCTIYETEGPESATPAPG 681
Query: 561 GPEPELSPITEGSEARAGPPAPAPPAPIPPPAPSQSSPPEQPQSMEMRSVLR 612
+P SP T G +A AG A A +P Q+ E P SV++
Sbjct: 682 ALDPGPSPGTSGGKAAAGAGAGASSR-----SPKQARLGELPLGALQASVVQ 728
Score = 76.6 bits (187), Expect = 9e-14
Identities = 160/573 (27%), Positives = 206/573 (35%), Gaps = 118/573 (20%)
Query: 55 APPGPQA--GPPSRPPRYSSSSIPEPFGSRGSPRKAATDGADTPFGRSESAPTLHPYSPL 112
APP GP S P R S ++ P P G +G A A G++ AP S
Sbjct: 94 APPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR---GKATEAPKRSALS-- 148
Query: 113 SPKGRPSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLG---RAPSPRPGPGPLRQQ 169
+ R +S TP G+ A + R RA AG+ +G APS RP P +
Sbjct: 149 AGARRDTSGPTP--------GTPSPAMARRSRA---AGTEVGLPRPAPSARPRP---PTE 194
Query: 170 GPPTPFDFLGRAGSPRGSPLA-EGPQAFFPERGPSPR---PPATAYDAPASAFGSSLLGS 225
GP + SP A P A + P+ R AT +PA + G S G+
Sbjct: 195 GPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARS-GPSARGT 253
Query: 226 GGSAFAPPLRAQDDLTLRRRPPKAWNESDLDVAYEKKPSQTASYERLDVFARP---ASPS 282
A A P + + RPP+ D A P ++ A P A PS
Sbjct: 254 -PRAPAHPSQPKPKGLQALRPPQV-TPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPS 311
Query: 283 LQLLPWRESSLDGLGGTGKDNLTSATLPRNYK------VSPLASDRRSDAGSYRRSLGSA 336
LQ LP ++ T +L S TL + +SPLA+ A
Sbjct: 312 LQTLPSPPATPPSQATT---SLGSPTLQATHSFLPSPPLSPLATPP-----------PQA 357
Query: 337 GPSGTLPRSWQPVSRIPMPPSSP--QPRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLPG 394
P+ LP P+ P PP+SP P P + + LQ F P
Sbjct: 358 PPALALP----PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPF--------SPPP 405
Query: 395 SPLFTRAPPPKLQPQPQPQPQPQSQPQPQLPPQP-QTQPQTPTPAPQHPQQTWPPVNEGP 453
SP P P P P SQ P L P Q P P P P T PP + P
Sbjct: 406 SPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP--QAP 463
Query: 454 P---KPPTEL-EPEPEI-EGLLTPVLEA--GDVDEGPVARPLSPTRLQPALP---PEAQS 503
P PP +L +P P+ L TP L+A P P SP+ P P P Q+
Sbjct: 464 PPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQA 523
Query: 504 VPELEEVARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPE 563
P L A L ++P P QAP PPT PGP
Sbjct: 524 PPVL---AAPLLQVP-PSPPASPTLQAP--RRPPT------------------PGP---- 555
Query: 564 PELSPITEGSEARAGPPAPAPPAPIPPPAPSQS 596
+ +GP AP PPP PS+S
Sbjct: 556 ---------DTSVSGPRLTLALAPGPPPPPSRS 579
Score = 42.0 bits (97), Expect = 0.002
Identities = 79/342 (23%), Positives = 109/342 (31%), Gaps = 66/342 (19%)
Query: 330 RRSLGSAGPSGTLPRSWQPVSRIPMPPSSPQP--------------RGAPRQRPIPLSMI 375
+R AG + P + P P PP SP+P GA ++P+
Sbjct: 4 KRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPL-AERA 62
Query: 376 FKLQNAFWEHGASRA------MLPGSPLFTRAPPPK-LQPQPQPQPQPQS---QPQP--- 422
+ A A RA P S RAPP K P P P S +P P
Sbjct: 63 GGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQ 122
Query: 423 -----------------QLPPQP--------QTQPQTP-TPAPQHPQQTWPPVNE-GPPK 455
+ P + T TP TP+P +++ E G P+
Sbjct: 123 KGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPR 182
Query: 456 PPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPALPPEAQSVPELEEVARVLA 515
P P P EG P E P R +P+ Q P ++
Sbjct: 183 PAPSARPRPPTEG---PRKSVSSASEHSTTEPSPAARRRPSAGGGLQR-PASRSLSSSAT 238
Query: 516 EIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPELSPITEGSEA 575
+ P + S P P+ K + + L P P L P++ A
Sbjct: 239 PLSSPARSGPSARGTPRAPAHPSQPK--PKGLQALRPPQVTPPRKDAAPALGPLSSSPLA 296
Query: 576 RAGPPAPAPPAPIPPPAPSQSSPPEQPQSMEMRSVLRKAGSP 617
P AP P+ PP + SPP P S S+ GSP
Sbjct: 297 TPSPSAPPSPS-APPSLQTLPSPPATPPSQATTSL----GSP 333
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 92.8 bits (229), Expect = 1e-18
Identities = 159/577 (27%), Positives = 205/577 (35%), Gaps = 89/577 (15%)
Query: 41 ELTKQLES-LWSDSPAPPGPQAGPPSRPPRYSSSSIPEPFGSRGSPRKAATDGADTPFGR 99
+L QLE+ L + P P P+ P S PP S +S P P SR SP + P
Sbjct: 425 QLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTS-PPPEASRLSPPPEELPASPLPEAL 483
Query: 100 SESAPTLHPYSPLSPKGRPSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRAPSP 159
S P SPLSP SP +P P F S P
Sbjct: 484 HLSRPL--EESPLSPPPE-ESPLSP---------------PPESSPFSPLEESPLSPPEE 525
Query: 160 RPGPGPLRQQGPPTPFDFLGRAGSPRGSPLAEGPQAFFPERGPSPRPPATAYDAPASAFG 219
P L P P SP P E P + PE P+ PP + +P
Sbjct: 526 SPPSPALETPLSPPP------EASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEES 579
Query: 220 SSLLGSGGSAFAPPLRAQDDLTLRRRPPKAWNESDLDVAYEKKP-SQTASYERLDVFARP 278
S +PP A R PP + ES L E+ P S RL + P
Sbjct: 580 PMSPPPEESPMSPPPEAS-----RLFPP--FEESPLSPPPEESPLSPPPEASRL---SPP 629
Query: 279 ASPSLQLLPWRESSLDGLGGTGKDNLTSATLPRNYKVSPLASDRRSDAGSYRRSLGSAGP 338
S P ES + + P ++SPL R L + P
Sbjct: 630 PEDSPMSPPPEESPM-------------SPPPEVSRLSPLPVVSRLSPPPEESPL--SPP 674
Query: 339 SGTLPRSWQP-VSRIPMP----PSSPQPRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLP 393
P S P SR+ P P+SP P +P P P + L + LP
Sbjct: 675 PEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPP-PEDSLMSLP----LEESPLLPLP 729
Query: 394 GSP-LFTRAPPPKLQPQPQ-----PQP-QPQSQPQ---PQLPPQPQTQPQTPTPAPQH-- 441
P L R+ P L P+P+ P+P +P PQ P L PQP+ P H
Sbjct: 730 EEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLS 789
Query: 442 PQQTWPPVNEGPPKPPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPAL---P 498
PQ P ++ P + L P+ E E L+PV E + P LSP +P L P
Sbjct: 790 PQAEGPHLSPQPEE--LHLSPQTE-EPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRP 846
Query: 499 PEAQSVPELEEVARVLAEIPRPLKRRGSMEQAPA----VALPPTHKKQYQQIISRLFHRH 554
E+ PELE+ PRP K Q PA PP + ++
Sbjct: 847 EESHLSPELEKPPL----SPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSE 902
Query: 555 GGPGPGGPEPELSPITEGSEARAGPPAPAPPAPIPPP 591
G P P PE P++ E P PP P+PPP
Sbjct: 903 PGEPPLSPLPEELPLSPSGEPSLSPQL-MPPDPLPPP 938
Score = 73.2 bits (178), Expect = 9e-13
Identities = 63/218 (28%), Positives = 86/218 (39%), Gaps = 24/218 (11%)
Query: 402 PPPKLQPQPQPQPQPQSQPQPQLP--PQPQTQPQTPTPAPQHPQQTWPPVNEGPPKPPTE 459
PP +L P P+ S+P + P P P+ P +P P + P+ E P PP E
Sbjct: 470 PPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPE----SSPFSPLEESPLSPPEE 525
Query: 460 LEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPALPPEAQSVPELEEVARVLAEIPR 519
P P +E L+P EA P++ P + L P PPE E +R+ P
Sbjct: 526 SPPSPALETPLSPPPEA-----SPLSPPFEESPLSP--PPEELPTSPPPEASRL---SPP 575
Query: 520 PLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPELSPITEGSEARAGP 579
P E++P P SRLF P P PE SP++ EA
Sbjct: 576 P-------EESPMSPPPEESPMSPPPEASRLFPPF-EESPLSPPPEESPLSPPPEASRLS 627
Query: 580 PAPAPPAPIPPPAPSQSSPPEQPQSMEMRSVLRKAGSP 617
P P PPP S SPP + + V+ + P
Sbjct: 628 PPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPP 665
Score = 72.0 bits (175), Expect = 2e-12
Identities = 76/290 (26%), Positives = 103/290 (35%), Gaps = 66/290 (22%)
Query: 338 PSGTLPRSWQPVSRIPMPPSSPQPRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLPG--S 395
P+ LP + + P SP P +P P S L+ + P +
Sbjct: 475 PASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALET 534
Query: 396 PLFTRAPPPKLQPQPQP-QPQPQSQPQPQLP-----------PQPQTQPQTPTPA----- 438
PL +PPP+ P P + P S P +LP P P+ P +P P
Sbjct: 535 PL---SPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMS 591
Query: 439 -PQHPQQTWPPVNEGPPKPPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPAL 497
P + +PP E P PP E P L+P EA + P P+SP
Sbjct: 592 PPPEASRLFPPFEESPLSPPPEESP-------LSPPPEASRLSPPPEDSPMSP------- 637
Query: 498 PPEAQSVPELEEVARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGP 557
PPE + EV+R+ P P+ R S PP +
Sbjct: 638 PPEESPMSPPPEVSRL---SPLPVVSRLS---------PPPEE----------------- 668
Query: 558 GPGGPEPELSPITEGSEARAGPPAPAPPAPIPPPAPSQSSPPEQPQSMEM 607
P P PE SP + EA P P PPP S +SPP + M +
Sbjct: 669 SPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSL 718
Score = 71.6 bits (174), Expect = 3e-12
Identities = 135/562 (24%), Positives = 184/562 (32%), Gaps = 134/562 (23%)
Query: 101 ESAPTLHPYSPLSPKGRPSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRAPSPR 160
+ P +SP P P+ LY+ TS +P+
Sbjct: 364 QHTPVCSRFSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKE--------------- 408
Query: 161 PGPGPLRQQGPPTPFDFLGRAG--------------SPRGSPLAEGPQAFFPERGP-SPR 205
PGPL+ + P LG+AG P P E P + PE P SP
Sbjct: 409 --PGPLQCEAKP-----LGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPP 461
Query: 206 PPATAYDAPASAFGSSLLGSGGSAFAP----PLRAQDDLTLRRRPPKAWNESDLDVAYEK 261
P A+ P +S L P PL + + PP++ S L+ +
Sbjct: 462 PEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLS 521
Query: 262 KPSQTASYERLDVFARPASPSLQ--LLPWRESSLDGLGGTGKDNLTSATLPRNYKVSPLA 319
P ++ P SP+L+ L P E+S L ++ SPL+
Sbjct: 522 PPEES-----------PPSPALETPLSPPPEAS---------------PLSPPFEESPLS 555
Query: 320 SDRRSDAGSYRRSLGSAGPSGTLPRSWQP-VSRIPMPPS----SPQPRGAPRQRPIPLSM 374
P LP S P SR+ PP SP P +P P S
Sbjct: 556 P-----------------PPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASR 598
Query: 375 IFKLQNAFWEHGASRAMLPGSPLFTRAPPPKLQP-QPQPQPQPQSQPQPQLPPQPQTQPQ 433
+F +E SPL +PPP+ P P+ P S P + P P +
Sbjct: 599 LFPP----FEESPLSPPPEESPL---SPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVS 651
Query: 434 TPTPAPQHPQQTWPPVNEGPPKPPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPT-R 492
+P P + + PP E P PP E P +P EA + P P SP
Sbjct: 652 RLSPLPVVSRLS-PPPEESPLSPPPEESPT-------SPPPEASRLSPPPEDSPTSPPPE 703
Query: 493 LQPALPPEAQSVPEL---EEVARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIIS- 548
PA PP S+ L E L E P+ R +P P + + +S
Sbjct: 704 DSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSP 763
Query: 549 RLFHRHGGPGPGGP-------EPELSPITEGSEARAGP---------------PAPAPPA 586
+ H P P P EP LSP EG P P P P
Sbjct: 764 QAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPC 823
Query: 587 PIPPPAPSQSSPPEQPQSMEMR 608
P P S SP + + R
Sbjct: 824 LSPQPEESHLSPQSEEPCLSPR 845
Score = 70.9 bits (172), Expect = 5e-12
Identities = 163/659 (24%), Positives = 227/659 (34%), Gaps = 119/659 (18%)
Query: 52 DSPAPPGPQAGPPSRPPRYSSSSIPEPFGSRGSPRKAATDGADTPFGRSESAPTLHPYSP 111
+SP P P+ P S PP SP + +P S +P L +P
Sbjct: 491 ESPLSPPPEESPLSPPPE-------------SSPFSPLEESPLSPPEESPPSPALE--TP 535
Query: 112 LSPKGRPSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRAPSPRPGPGPLRQQGP 171
LSP S P P + + TSP P A + SP P P+ P
Sbjct: 536 LSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSP--P 593
Query: 172 PT------PFDFLGRAGSPRGSPLAEGPQAFF----PERGP-SPRPPATAYDAPASAFGS 220
P PF+ + P SPL+ P+A PE P SP P + P
Sbjct: 594 PEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRL 653
Query: 221 SLLGSGGSAFAPP----LRAQDDLTLRRRPPKAWNESDLDVAYEKKPSQTASYERLDVFA 276
S L PP L + + PP+A S L E P+ +
Sbjct: 654 SPLPVVSRLSPPPEESPLSPPPEESPTSPPPEA---SRLSPPPEDSPTSPPPEDS----- 705
Query: 277 RPASP----SLQLLPWRESSLDGLGGTGKDNLTSATLPRNYKVSPLASDRRSDAG-SYRR 331
PASP SL LP ES L L + PR+ P S R + S R
Sbjct: 706 -PASPPPEDSLMSLPLEESPLLPLPEEPQ------LCPRSE--GPHLSPRPEEPHLSPRP 756
Query: 332 SLGSAGPSGTLPR-SWQP----VSRIPMPPS-SPQPRGAPRQRPIPLSMIFKLQ------ 379
P P S QP + +P P SPQ G P P P + Q
Sbjct: 757 EEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEG-PHLSPQPEELHLSPQTEEPHL 815
Query: 380 NAFWEHGASRAMLPGSPLFTRAPPPKLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAP 439
+ E S L ++ P L P+P+ +P L P+P+ P+ P P
Sbjct: 816 SPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCP 875
Query: 440 QHPQQTWPPVNEGPPKPPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPALPP 499
+ P PP P+ L+P+L + E P PLSP L LP
Sbjct: 876 APEELPLFP----PPGEPS-----------LSPLLGEPALSE-PGEPPLSP--LPEELPL 917
Query: 500 EAQSVPELEEVARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGP 559
P L +P PL + A AL P + +Y G G
Sbjct: 918 SPSGEPSLSPQLMPPDPLPPPLS--PIITAAAPPALSPLGELEYP---------FGAKGD 966
Query: 560 GGPEPEL------SPITEGSEARAGPPAPAPPAPIPPPAPSQSSPPEQPQSME-----MR 608
PE L +PI+ EA P P PP I PP+P P P ME
Sbjct: 967 SDPESPLAAPILETPISPPPEANCTDPEPVPPM-ILPPSPGSPVGPASPILMEPLPPQCS 1025
Query: 609 SVLRKAGSPRKARRARLNPLVLLLD-----------AALTGELEVVQQAVKEMNDPSQP 656
+L+ + P+ + ++ +P L L ++ E E+ + +++++P P
Sbjct: 1026 PLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECP 1084
Score = 62.0 bits (149), Expect = 2e-09
Identities = 160/647 (24%), Positives = 216/647 (33%), Gaps = 156/647 (24%)
Query: 27 LKQMELDTAAAKVDELTKQLESLWSDSPAPPGPQAGPPSRPPRYSSSSIPEPFGSRGSPR 86
L++ + + AA +++++ KQ ES + G A RP + IP G+ GSP
Sbjct: 2061 LQKAKDNRAAHRINKVQKQAESQ-INKQTKVGDIARKTDRPALHLR--IPPQPGALGSPP 2117
Query: 87 KAATDGADTPFGRSESAPTLHPYSPLSPKGRPSS------PRTPLYLQPDAYGSLDRATS 140
AA APT+ SP +P G +S P PD+ G L
Sbjct: 2118 PAA-------------APTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLP 2164
Query: 141 PRPRAFDGAGSSLGRAPS----PR---------PGPGPLRQQGPPTPFDFLGRAGSPRGS 187
P+ A + G AP+ PR P P P P R G+ +
Sbjct: 2165 PQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPG 2224
Query: 188 PLAEGPQAFFPERGPSPRPPATAYDAPA--SAFGSSLLGSGGSAFAPPLRAQDDLTLRRR 245
P P PS P P+ + G GG + PL +
Sbjct: 2225 EFHTTPPGT-PRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSP-------- 2275
Query: 246 PPKAWNESDLDVAYEKKPSQTASYERLDVFARPASPSLQLL--PWRESSLDGLGGTGKDN 303
PP + L+V E+ + + SY P+L + P + L GL D
Sbjct: 2276 PPFGESRKALEVKKEELGASSPSY---------GPPNLGFVDSPSSGTHLGGLELKTPDV 2326
Query: 304 LTSATLPRNYKVSPLASDRRSDAGSYRRSLGSAGPSGTLPRSWQPVSRI-PMPPSSP--- 359
+ PR +V P + G P+ P + P PPS P
Sbjct: 2327 FKAPLTPRASQVEPQSPGL-----------------GLRPQEPPPAQALAPSPPSHPDIF 2369
Query: 360 ----------QPRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLPGSPLFTRAPPPKLQPQ 409
QP PR +P P L LP P F+R P PQ
Sbjct: 2370 RPGSYTDPYAQPPLTPRPQPPPPESCCALPPR---------SLPSDP-FSRVPA---SPQ 2416
Query: 410 PQPQPQPQSQPQP----QLPPQPQTQP-QTPTP---APQHPQQTWP--PVNEGP-PKPPT 458
Q Q P+P P P T Q+P P P PQ P P+++ P P+PP
Sbjct: 2417 SQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPP- 2475
Query: 459 ELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPALPPEAQSVPELEEVARVLAEIP 518
E + L L AG P A P P A P Q P A +
Sbjct: 2476 --EVAFKAGSLAHTSLGAGGF---PAALPAGPAGELHAKVPSGQP-PNFVRSPGTGAFVG 2529
Query: 519 RPLKRRGSMEQA----------PAVALPPTHKKQYQQIISRLFHRHGGPGP--------- 559
P R + QA P LPP H + H GPGP
Sbjct: 2530 TPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHG----------INSHFGPGPTLGKPQSTN 2579
Query: 560 -----GGPEPELSPI--TEGSEARAGPPAPA-PPAPIPPPAPSQSSP 598
G P SP+ + GS + +P PP+ +PPPAP S P
Sbjct: 2580 YTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLP 2626
Score = 55.8 bits (133), Expect = 2e-07
Identities = 174/674 (25%), Positives = 224/674 (33%), Gaps = 174/674 (25%)
Query: 56 PPGPQ-AGPPSRPPRYSSSSIPEPFGSRGSPRKAATDGADTPFGR-SESAPTLHPYSP-L 112
PP P G P++PP +SS P G P + T TP + S P L P P L
Sbjct: 2197 PPYPSPTGAPAQPPMLGASSRP----GAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSL 2252
Query: 113 SPKGRPSSPRT-------PLYLQPDAYGSLDRATSPRPRAFDGAGSS-----LGRAPSPR 160
P SP PL L P +G +A + + S LG SP
Sbjct: 2253 DNLAVPESPGVGGGKASEPL-LSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPS 2311
Query: 161 PGP--GPLRQQGPPTPFDFLGRAGSPRGSPLAEGPQAFFPERGPSPRPPATAYDAPASAF 218
G G L + P D +PR S + PQ+ P PPA A AP+
Sbjct: 2312 SGTHLGGLELKTP----DVFKAPLTPRASQVE--PQSPGLGLRPQEPPPAQAL-APSPPS 2364
Query: 219 GSSLLGSGGSAFAPPLRAQDDLTLRRRPPKAWNESDLDVAYEKKPSQTASYERLDVFAR- 277
+ G ++ P AQ LT R +PP ES + PS D F+R
Sbjct: 2365 HPDIFRPG--SYTDPY-AQPPLTPRPQPPPP--ESCCALPPRSLPS--------DPFSRV 2411
Query: 278 PASPSLQLLPWRESSLDGLGGTGKDNLTSATLPRNYKVSPLASDRRSDAGSYRRSLGSAG 337
PASP Q + S PR PL+++ +
Sbjct: 2412 PASPQSQ-----------------SSSQSPLTPR-----PLSAE-------------AFC 2436
Query: 338 PSGTLPR--SWQPVSRIPMPPSSPQPRG--APRQ---RPIPLSMIFK---LQNAFWEHGA 387
PS PR S P SR PPS PQ R AP RP P + FK L + G
Sbjct: 2437 PSPVTPRFQSPDPYSR---PPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGG 2493
Query: 388 SRAMLPGSP---LFTRAP---PPKLQPQPQP-----QPQPQSQPQPQLPPQPQTQPQTPT 436
A LP P L + P PP P P P PQ +P +P P
Sbjct: 2494 FPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQ 2553
Query: 437 PAPQHPQQTWPPVNEGPPKPPTELEPEPEIEGLLTPVLEAGDVDEGPVARP------LSP 490
P P +N PT +P+ + T GP + LSP
Sbjct: 2554 PGLPPPHG----INSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSP 2609
Query: 491 TRLQPALPPEAQ--SVPELEEVARVLAEIPRPLKRR-----GSMEQAPAVALPPTH---- 539
R LPP A S+P L A + I P+++R G LP T
Sbjct: 2610 LRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGM 2669
Query: 540 ---------KKQYQQIISRLFHRH---------------------GGPGPGGPEPELSPI 569
K++ +Q + L R G PG G EP SP
Sbjct: 2670 SGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPS-SPA 2728
Query: 570 -------------TEGSEARAGPPAPAPPAPIPPPAP-------SQSSPPEQPQSMEMRS 609
T+ + G P PI P S+ PP P SM++ S
Sbjct: 2729 FEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNS 2788
Query: 610 VLRKAGSPRKARRA 623
GS +RA
Sbjct: 2789 RQLVGGSQAFYQRA 2802
Score = 54.7 bits (130), Expect = 3e-07
Identities = 144/589 (24%), Positives = 197/589 (33%), Gaps = 116/589 (19%)
Query: 52 DSPAPPGPQAGPPSRPPRYSSSSIPEPFGSRGSPRKAATDGADTPFGRSESAPTLHPYSP 111
DSP P P+ P S PP S S+P ++P P L P S
Sbjct: 695 DSPTSPPPEDSPASPPPEDSLMSLPL---------------EESPLLPLPEEPQLCPRSE 739
Query: 112 ---LSPKGRPSSPRTPLYLQPDAYGSLDRATSPR--PRAFDGAGSSLGRAPSPRPGPGPL 166
LSP RP P L +P+ +A P P+ + ++ P P
Sbjct: 740 GPHLSP--RPEEPH--LSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSP----- 790
Query: 167 RQQGPPTPFDFLGRAGSPRGSPLAEGPQAFFPERGPSPRPPATAYDAPASAFGSSLLGSG 226
+ +GP SP+ L PQ P P P P + S S
Sbjct: 791 QAEGPHL---------SPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQ---SE 838
Query: 227 GSAFAP-PLRAQDDLTLRRRPPKAWNESDLDVAYEKKPSQTASYERLDVFARPASPSLQL 285
+P P + L + P E ++P Q + E L +F P PSL
Sbjct: 839 EPCLSPRPEESHLSPELEKPPLSPRPEKP-----PEEPGQCPAPEELPLFPPPGEPSLSP 893
Query: 286 LPWRESSLDGLGGTGKDNLTSATLPRNYKVSPLASDRRSDAGSYRRSLGSAGPSGTLPRS 345
L + L G+ L + LP +SP S PS L
Sbjct: 894 LLGEPA----LSEPGEPPL--SPLPEELPLSP-----------------SGEPS--LSPQ 928
Query: 346 WQPVSRIPMPPSSPQPRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLPGSPLFTR----- 400
P +P PP SP A P LS + +L+ F G S P SPL
Sbjct: 929 LMPPDPLP-PPLSPIITAA---APPALSPLGELEYPFGAKGDSD---PESPLAAPILETP 981
Query: 401 -APPPK---LQPQPQP----QPQPQSQPQPQLPPQPQTQPQTPTPAPQHP--QQTWPPVN 450
+PPP+ P+P P P P S P P + P +P QH Q PP
Sbjct: 982 ISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQ 1041
Query: 451 EGPPKPPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPALPPEAQSVPELEEV 510
PP P + G + V + ++ E + P PAL P A S
Sbjct: 1042 CSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPE--CPALEPSATS------- 1092
Query: 511 ARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGG-PEPELSPI 569
+P P+ +PA AL + + G PG PEP +P
Sbjct: 1093 -----PLPSPMGDLSCPAPSPAPAL-----DDFSGLGEDTAPLDGIDAPGSQPEPGQTPG 1142
Query: 570 TEGSEARAGPPAPAPPAPIPPPAPSQSSPPEQPQSMEMRSVLRKAGSPR 618
+ SE + G P P + P P + PE Q+ S + PR
Sbjct: 1143 SLASELK-GSPVLLDPEELAPVTPMEVY-PECKQTAGQGSPCEEQEEPR 1189
Score = 46.6 bits (109), Expect = 9e-05
Identities = 101/414 (24%), Positives = 134/414 (32%), Gaps = 86/414 (20%)
Query: 118 PSSPRTPL--YLQPDAYGSLDRATSPRPRAFDGAGSSLGRAPSPRPGPGPLRQQGPP--- 172
P P PL + P A G T D A SS GP QG P
Sbjct: 3999 PGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSS-------EATEGPSTHQGGPLAI 4051
Query: 173 --TPFDFLGRAGSPRGSPLAEGPQAFFPERGPSPRPPATAYDAPA--------------S 216
TP G + S L+ Q + P P+P + P +
Sbjct: 4052 GTTPESMATEPGEVKPS-LSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHT 4110
Query: 217 AFGSS--LLGSGGSAFA---PPLRAQDDLTLRRRPPK-AWNESDLDVAYEKKPSQTASYE 270
A G S LGSG S+ A P L AQ ++L +P N ++P Q
Sbjct: 4111 AGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQN---- 4166
Query: 271 RLDVFARPASPSLQLLPWRESSLDGLGGTGKDNLTSATLPRNYKVSPLASDRRSDAGSYR 330
+ +P P L S GL G G + P R+
Sbjct: 4167 --NTGPQPPKPGPVL-----QSGQGLPGVG--------------IMPTVGQLRAQL---- 4201
Query: 331 RSLGSAGPSGTLPRSWQPVSRIPMPPSSPQPRGAPRQRPIPLSMIFKLQNAFWEHGASRA 390
G L ++ P R P Q + QR + S + + E G +
Sbjct: 4202 --------QGVLAKN--PQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTS 4251
Query: 391 MLPG----SPLFTRAPPPKLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTW 446
L G P P P+ P + P+ Q P+LP P P P HP T
Sbjct: 4252 PLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHP--TP 4309
Query: 447 PPVNEGPPKPPTELEPEPE----IEGLLTPVLEAGDVDEGPVARPLSPTRLQPA 496
PP + PK P++L P P E L P +GP P P R+ PA
Sbjct: 4310 PPSSPQEPKRPSQL-PSPSSQLPTEAQLPPTHPGTPKPQGPTLEP-PPGRVSPA 4361
Score = 45.8 bits (107), Expect = 2e-04
Identities = 69/294 (23%), Positives = 99/294 (33%), Gaps = 58/294 (19%)
Query: 355 PPSSPQPRGAPRQRPIPLSMIFKLQNAFWEH--GASRAMLPGSPLFTRAPPPKLQPQP-- 410
P PQP Q P+ L + Q + G S L + P L QP
Sbjct: 4080 PQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSV 4139
Query: 411 ----QPQPQPQS-----QPQPQLPPQPQTQPQTPTPAPQHPQQTWPPVNEGPPKPPTELE 461
QP Q+ QP + P Q T PQ P P P P G PT +
Sbjct: 4140 SLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLP---GVGIMPTVGQ 4196
Query: 462 PEPEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPALPPEAQSVPELEEVARVLAEIPRPL 521
+++G+L + P R LSP + Q ++ +L + R L
Sbjct: 4197 LRAQLQGVLA---------KNPQLRHLSPQQQQ--------------QLQALLMQ--RQL 4231
Query: 522 KRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGP---------GGPEPELSP---- 568
++ ++ Q P P T Q ++ G PGP GP P+ P
Sbjct: 4232 QQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPA 4291
Query: 569 ----ITEGSEARAGPPAPAPPAPIPPPAPSQSSPPEQPQSMEMRSVLRKAGSPR 618
++ G P P P +P P PSQ P E + G+P+
Sbjct: 4292 PPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPK 4345
Score = 45.1 bits (105), Expect = 3e-04
Identities = 148/608 (24%), Positives = 206/608 (33%), Gaps = 82/608 (13%)
Query: 20 LAMKHMDLKQMELDTAAAKVDELTKQLESLWSDSPAPPGPQAGPPSRPPRYSSSSIPEPF 79
L +K D+ + L A++V+ + L + P PPS P + S +P+
Sbjct: 2319 LELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPY 2378
Query: 80 GSRGSPRKAATDGADTPFGRSESAPTLHPYSPLSPKGRPSSPRTPLYLQPDAYGSLDRAT 139
A P P L P+ PS P + + P + S
Sbjct: 2379 -------------AQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPL 2425
Query: 140 SPRPRAFDGAGSSLGRAPSPRPGPGPLRQQGPPTPFDFLGRAGSPRGSPLAEGPQAFFP- 198
+PRP + A + P P R Q P P+ P P + P F P
Sbjct: 2426 TPRPLS----------AEAFCPSPVTPRFQS-PDPY------SRPPSRPQSRDP--FAPL 2466
Query: 199 ERGPSPRPPATAYDAPASAFGSSLLGSGGSAFAPPLRAQDDLTLR--RRPPKAWNESDLD 256
+ P P+PP A+ A + A S LG+GG A P +L + P + S
Sbjct: 2467 HKPPRPQPPEVAFKAGSLAHTS--LGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGT 2524
Query: 257 VAYEKKPSQ---TASYERLDVFARPASPSLQLLPWRE-SSLDGLGGT-GK---DNLTSAT 308
A+ PS T + +P P L P +S G G T GK N T AT
Sbjct: 2525 GAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVAT 2584
Query: 309 LPRNYKVSPLASDRRSDAGSYRRSLGSAGPSGTLPRSWQPVSRIPMPPSS-PQPRGAPRQ 367
+ SPL S SY L P LP P P S P Q
Sbjct: 2585 GNFHPSGSPLGPSSGSTGESY--GLSPLRPPSVLPP--------PAPDGSLPYLSHGASQ 2634
Query: 368 RPIPLSMIFKLQNAFWEHGAS--RAMLPGSPLFTRAPPPKLQPQPQPQPQPQSQPQPQLP 425
R S + K ++ G+S A LPG T+ P Q + + Q Q Q +L
Sbjct: 2635 RSGITSPVEKREDPGTGMGSSLATAELPG----TQDPGMSGLSQTELEKQRQRQRLRELL 2690
Query: 426 PQPQTQPQTPTPAPQHPQQTWPPVNEGPPKPPTELEPEPEIEGL---LTPVLEAGDVD-- 480
+ Q Q T + V GPP P E L TP D
Sbjct: 2691 IRQQIQRNTLRQEKETAAAAAGAV--GPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSL 2748
Query: 481 --------EGPVARPLS-PTRLQPALPPEAQSVPELEEVARVLAEIPRPLKRRGSMEQAP 531
GP+ P S P+ + + PP + ++ +R L + +R +
Sbjct: 2749 VGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSL 2808
Query: 532 AVALPPTHKKQYQQIISRLFHRHGGPG--PGGPEPELSPITEGSE-ARAGPPAPAPPAPI 588
+ Q QQ + R P P PEL GS A P P P+
Sbjct: 2809 PLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPGEPV 2868
Query: 589 PPPA-PSQ 595
P PA P+Q
Sbjct: 2869 PGPAGPAQ 2876
Score = 42.0 bits (97), Expect = 0.002
Identities = 22/70 (31%), Positives = 33/70 (47%), Gaps = 9/70 (12%)
Query: 401 APPPKLQPQPQPQP------QPQSQPQPQLPPQPQTQPQTPTPAP--QHPQQTWPPVNEG 452
APPP+ +P P P P P ++P +LP +P +P P+P P P+ P
Sbjct: 4908 APPPE-EPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRAR 4966
Query: 453 PPKPPTELEP 462
PP+ + P
Sbjct: 4967 PPEEGEDSRP 4976
Score = 40.8 bits (94), Expect = 0.005
Identities = 79/335 (23%), Positives = 113/335 (33%), Gaps = 61/335 (18%)
Query: 338 PSGTLPRSWQPVSR-IPMPPSSPQPRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLPGSP 396
P+G++P P + +PP P P Q P L+ + L+ F + P SP
Sbjct: 2146 PAGSVPGPDSPGELFLKLPPQVPAQ--VPSQDPFGLAPAYPLEPRFPTAPPTYPPYP-SP 2202
Query: 397 LFTRAPPPKLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTP--APQHPQQTWPPVNEGP- 453
A PP L +P + P P+ QP TP P P+ P V E P
Sbjct: 2203 TGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPG 2262
Query: 454 ------------PKPPTE----LEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRL---- 493
P P E LE + E G +P G + G V P S T L
Sbjct: 2263 VGGGKASEPLLSPPPFGESRKALEVKKEELGASSP--SYGPPNLGFVDSPSSGTHLGGLE 2320
Query: 494 --------QPALPPEAQSVPELEEVARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQ 545
P P +Q P+ + E P S P + P ++ Y Q
Sbjct: 2321 LKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQ 2380
Query: 546 IISRLFHRHGGPGPGG---------PEPELSPITEGSEARAGPPAPAPPAPI------PP 590
L R P P P S + ++++ +P P P+ P
Sbjct: 2381 --PPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPS 2438
Query: 591 PAPSQ-------SSPPEQPQSMEMRSVLRKAGSPR 618
P + S PP +PQS + + L K P+
Sbjct: 2439 PVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQ 2473
Score = 39.7 bits (91), Expect = 0.012
Identities = 52/178 (29%), Positives = 69/178 (38%), Gaps = 29/178 (16%)
Query: 405 KLQPQPQPQPQPQSQPQPQLPPQPQTQP-----QTPTP-APQHPQQTWPPVNEGPPKPPT 458
+LQ Q Q Q Q Q Q Q Q Q Q Q+ T +PQ QQ + G P P
Sbjct: 3947 QLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPL 4006
Query: 459 ELEPEPEIEG--LLTPVLEAGDVD--------EGPVARPLSPTRLQPALPPEAQSV---- 504
+ P G LL E VD EGP P + PE+ +
Sbjct: 4007 QHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAI--GTTPESMATEPGE 4064
Query: 505 --PELEEVARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPG 560
P L +++L P+P + S++ P + LP Q QQ +S L H GG G
Sbjct: 4065 VKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLP----GQQQQQVS-LLHTAGGGSHG 4117
Score = 39.7 bits (91), Expect = 0.012
Identities = 33/112 (29%), Positives = 44/112 (39%), Gaps = 5/112 (4%)
Query: 390 AMLPGSPLFTRAPPPKLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPPV 449
A+LPG L ++ L Q P P+P +Q Q P P+ P P+
Sbjct: 4862 AVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPL 4921
Query: 450 NEGPPKPPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRLQP-ALPPE 500
P PPT EP +E P+ E P+A R +P A PPE
Sbjct: 4922 APSPASPPT----EPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPE 4969
Score = 39.3 bits (90), Expect = 0.015
Identities = 53/197 (26%), Positives = 63/197 (31%), Gaps = 76/197 (38%)
Query: 400 RAPPPKLQPQPQPQP-QPQSQPQPQLP--PQPQTQPQTPTPAPQHPQQTWPPVNEGPPKP 456
R PP +P Q P Q QPQL P PQT P A PQ GPP+
Sbjct: 4238 RQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQ--------GPPRL 4289
Query: 457 PTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPALPPEAQSVPELEEVARVLAE 516
P G + GPV P+ PT PP + P+
Sbjct: 4290 PAP----------------PGALSTGPVLGPVHPTP-----PPSSPQEPK---------- 4318
Query: 517 IPRPLKRRGSMEQAPAVA-LPPTHKKQYQQIISRLFHRHGGPGPGGPEPELSPITEGSEA 575
RP + Q P A LPPTH PG P+P+
Sbjct: 4319 --RPSQLPSPSSQLPTEAQLPPTH-------------------PGTPKPQ---------- 4347
Query: 576 RAGPPAPAPPAPIPPPA 592
GP PP + P A
Sbjct: 4348 --GPTLEPPPGRVSPAA 4362
Score = 35.4 bits (80), Expect = 0.22
Identities = 42/147 (28%), Positives = 47/147 (31%), Gaps = 27/147 (18%)
Query: 57 PGPQAGPPSRPPRYSSSSIPEPFGSRGSPRKAATDGADTPFGRSESAPTLHPYSPLSPKG 116
PGPQ GP + P P +G PR A GA + P L P P P
Sbjct: 4267 PGPQTGPLQE-----LGAGPRP---QGPPRLPAPPGA------LSTGPVLGPVHPTPPPS 4312
Query: 117 RPSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRAPSPRPG-PGPLRQQ------ 169
P P+ P L P L + P G G P PG P Q
Sbjct: 4313 SPQEPKRPSQL-PSPSSQLP-TEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLF 4370
Query: 170 ----GPPTPFDFLGRAGSPRGSPLAEG 192
GP P D L P S L G
Sbjct: 4371 SKGLGPWDPPDNLAETQKPEQSSLVPG 4397
Score = 33.9 bits (76), Expect = 0.64
Identities = 122/584 (20%), Positives = 194/584 (33%), Gaps = 150/584 (25%)
Query: 57 PGPQAGPPSRPPRYSSSSIPEPFGSRGSPRKAATDGADTPFGRSESAPTLHPYSPLSPKG 116
PGP GP RPP + +S P + +G GR P+ ++ +PK
Sbjct: 3091 PGP-LGPEERPPPAADASEPRLASVLPEVKPKVEEG-----GRH---PSPCQFTIATPKV 3141
Query: 117 RPSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRAPSPRPGPGPLRQQGPPTPFD 176
P+ A SL P G S+ + R G GP G
Sbjct: 3142 EPAP----------AANSLGLGLKP--------GQSMMGSRDTRMGTGPFSSSGHTAEKA 3183
Query: 177 FLGRAGSPRGSPLAEGPQAFFPERGPSPRPPATAYDAPASAFGSSLLGSGGSAFAPPLRA 236
G G P L P + GP ++ + G+ L G +A L
Sbjct: 3184 SFGATGGPPAHLLTPSPLS-----GPGGSSLLEKFELES---GALTLPGGPAASGDELDK 3235
Query: 237 QDDLTLRRRPPKAWNESDLDVAYEKKPSQTASYERLDVFARPASPSLQLLPWRESSLDGL 296
+ + P + + +EKK Q ++L +PA Q
Sbjct: 3236 MESSLVASELPLLIEDL---LEHEKKELQKK--QQLSAQLQPAQQQQQQQQ--------- 3281
Query: 297 GGTGKDNLTSATLPRNYKVSPLASDRRSDAGSYRR-SLGSAGPSGTLPRSWQPVSRIPMP 355
+ +L SA P P S AGS ++ SLG AG QP P+
Sbjct: 3282 ----QHSLLSAPGPAQAMSLPHEGSSPSLAGSQQQLSLGLAGAR-------QPGLPQPLM 3330
Query: 356 PSSPQPRGAPRQRPIPLSMIFKLQNAFW--EHGASRAMLPGSPLFTRAPPPKLQPQPQPQ 413
P+ P P A +QR P + Q +HG ++P Q Q
Sbjct: 3331 PTQP-PAHALQQRLAPSMAMVSNQGHMLSGQHGGQAGLVP---------------QQSSQ 3374
Query: 414 PQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPPVNEGPPKPPTELEPEPEIEGLLTPV 473
P +P +PP +PQ Q + P T+L+ + E ++ P+
Sbjct: 3375 PVLSQKPMGTMPPSMCMKPQQLAMQQQLANSFF---------PDTDLD-KFAAEDIIDPI 3424
Query: 474 LEAGDVDEGPVARPLSPTRLQPALPPEAQSVPELEEVARVLAEIPRPLKRRGSMEQAPAV 533
+A + L+ + +V+A+ GS+ AP +
Sbjct: 3425 AKA--------------------------KMVALKGIKKVMAQ--------GSIGVAPGM 3450
Query: 534 ALPPTHKKQYQQIISRLFHRHGGPGPGGPEPEL-SPITEGSEARAGPPAPAPPAPIPPP- 591
+++Q + RL GGP +L + + GS P+ P P PP
Sbjct: 3451 -----NRQQVSLLAQRL--------SGGPSSDLQNHVAAGSGQERSAGDPSQPRPNPPTF 3497
Query: 592 APSQSSPPEQPQ------------SMEMRSVLRKAGSPRKARRA 623
A + +Q Q M+++ + + G RK+R+A
Sbjct: 3498 AQGVINEADQRQYEEWLFHTQQLLQMQLKVLEEQIGVHRKSRKA 3541
Score = 32.7 bits (73), Expect = 1.4
Identities = 31/105 (29%), Positives = 41/105 (39%), Gaps = 11/105 (10%)
Query: 527 MEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPELSPITEGSEARAGPPAPAPPA 586
++Q AV LP K I+S L P P ++ + P P P+
Sbjct: 4857 LKQFDAV-LPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPS 4915
Query: 587 PIPPP-APSQSSPPEQP---------QSMEMRSVLRKAGSPRKAR 621
P P P APS +SPP +P + S L A SP AR
Sbjct: 4916 PPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESAR 4960
>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
sapiens]
Length = 1636
Score = 85.1 bits (209), Expect = 2e-16
Identities = 131/480 (27%), Positives = 169/480 (35%), Gaps = 83/480 (17%)
Query: 111 PLSPKGRPSSPRTPLYLQPDAYGSL--DRATSPR-PRAFDGAGSSLGRAPSPRP---GPG 164
PL P+ R S P+ SL D PR P F G+ + L PSP P GPG
Sbjct: 725 PLLPR-REESEAVEAGDPPEELRSLPPDMVAGPRLPDTFLGSATPLHFPPSPFPSSTGPG 783
Query: 165 PLRQQGPPTPFDFLG-------RAGSPRGSPLAEGPQ-----AFFPERGPSPR--PPATA 210
P GP P + G RA P P+A GP A+ PE G PR P
Sbjct: 784 PHYLSGPLPPGTYSGPTQLIQPRAPGPHAMPVAPGPALYPAPAYTPELGLVPRSSPQHGV 843
Query: 211 YDAPASAFGSSLLGSGGSAFAPPLRAQDDLTLRRRPPKAWNESDLDVAYEKKPSQTASYE 270
+P G + +G + PP + +L + RP + +D PS TA
Sbjct: 844 VSSPYVGVGPAPPVAGLPSAPPPQFSGPELAMAVRPAT----TTVDSIQAPIPSHTAP-- 897
Query: 271 RLDVFARPASPSLQLLPWRESSLDGLGGTGKDNLTSATLPRNYKVSPLASDRRSDAGSYR 330
R + P P + P + T T P K P+ + +G
Sbjct: 898 RPNPTPAPPPPCFPVPPPQPLP------------TPYTYPAGAK-QPIPAQHHFSSGI-- 942
Query: 331 RSLGSAGPSGTLPRSWQPVSRI-PMPPSSPQPRGAPRQRPIPLSMIFKLQNAFWEHGASR 389
P+G P RI P P PQP + P P LQ+ +
Sbjct: 943 -------PAGF------PAPRIGPQPQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAP 989
Query: 390 AMLPGSPLFTRAPPPKLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPPV 449
+LP + AP P + QP P Q P P P P P P+P PQ PP+
Sbjct: 990 GLLPPQSPYPYAPQPGVLGQPPPPLHTQLYPGPAQDPLPAHSGALPFPSPGPPQPPHPPL 1049
Query: 450 NEGPPKPPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPALPPEAQSVPELEE 509
GP + P+ + P AG P P PA P VP
Sbjct: 1050 AYGPAPSTRPMGPQAAPLTIRGP-SSAGQSTPSPHLVP------SPAPSPGPGPVP---- 1098
Query: 510 VARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGG-PGPGGPEPELSP 568
R A P P RRG+ A A L + + Q HGG PGG +P L P
Sbjct: 1099 -PRPPAAEPPPCLRRGA---AAADLLSSSPESQ-----------HGGTQSPGGGQPLLQP 1143
Score = 75.5 bits (184), Expect = 2e-13
Identities = 129/489 (26%), Positives = 153/489 (31%), Gaps = 125/489 (25%)
Query: 137 RATSPRP---RAFDGAGSSLGRAPSPRPGPGPLRQQGPPTPFDFLGRAGSPRGSPLAEGP 193
R T+P+P R + G P P GP P FLG A +PL P
Sbjct: 719 RPTAPKPLLPRREESEAVEAGDPPEELRSLPPDMVAGPRLPDTFLGSA-----TPLHFPP 773
Query: 194 QAFFPERGPSPR------PPATAYDAPASAFGSSLLGSGGSAFAPPLRAQDDLTLRRRPP 247
F GP P PP T Y P G AP P
Sbjct: 774 SPFPSSTGPGPHYLSGPLPPGT-YSGPTQLIQPRAPGPHAMPVAPGPALY--------PA 824
Query: 248 KAWNESDLDVAYEKKPSQTASYERLDVFARPASPSLQLLPWRESSLDGLGGTGKDNLTSA 307
A+ +L + P Q V PA P L G L A
Sbjct: 825 PAYTP-ELGLVPRSSP-QHGVVSSPYVGVGPAPPVAGLPSAPPPQFSG------PELAMA 876
Query: 308 TLPRNYKVSPLASDRRSDAGSYRRSLGSAGPSGTLPRS----WQPVSRIPMPPSSPQPRG 363
P V S+ + PS T PR P P+PP PQP
Sbjct: 877 VRPATTTVD---------------SIQAPIPSHTAPRPNPTPAPPPPCFPVPP--PQPLP 919
Query: 364 APRQRPIPLSMIFKLQNAFWEHGASRAMLPGSPLFTRAPPPKLQPQPQPQPQPQSQPQPQ 423
P P Q+ F S + P P++ PQPQP PQP P
Sbjct: 920 TPYTYPAGAKQPIPAQHHF-----------SSGIPAGFPAPRIGPQPQPHPQPH--PSQA 966
Query: 424 LPPQPQTQPQTPTPAPQHPQQTWPPVNEG--PPKPPTELEPEPEIEGLLTPVLEAGDVDE 481
PQP PQ P P QHP +PP G PP+ P P+P + G P L +
Sbjct: 967 FGPQP---PQQPLPL-QHPH-LFPPQAPGLLPPQSPYPYAPQPGVLGQPPPPLHT-QLYP 1020
Query: 482 GPVARPL----------SPTRLQPALPPEAQSVPELEEVARVLAEIPRPLKRRGSMEQAP 531
GP PL SP QP PP LA P P R + AP
Sbjct: 1021 GPAQDPLPAHSGALPFPSPGPPQPPHPP--------------LAYGPAPSTRPMGPQAAP 1066
Query: 532 AVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPELSPITEGSEARAGPPAPAP-PAPIPP 590
P+ G P P L P PAP+P P P+PP
Sbjct: 1067 LTIRGPS-----------------SAGQSTPSPHLVP----------SPAPSPGPGPVPP 1099
Query: 591 PAPSQSSPP 599
P+ PP
Sbjct: 1100 RPPAAEPPP 1108
Score = 44.7 bits (104), Expect = 4e-04
Identities = 57/216 (26%), Positives = 82/216 (37%), Gaps = 36/216 (16%)
Query: 405 KLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPPVNEGPPKP-------- 456
+L+ +P P+P + P+P LP + +++ P+ + P + GP P
Sbjct: 711 ELKKKPPPRP---TAPKPLLPRREESEAVEAGDPPEELRSLPPDMVAGPRLPDTFLGSAT 767
Query: 457 PTELEPEP----------EIEGLLTPVLEAGDVD------EGPVARPLSPTRLQPALPPE 500
P P P + G L P +G GP A P++P PAL P
Sbjct: 768 PLHFPPSPFPSSTGPGPHYLSGPLPPGTYSGPTQLIQPRAPGPHAMPVAP---GPALYPA 824
Query: 501 AQSVPELEEVARVLAEIPRPLKRRGSMEQAPAVA-LPPTHKKQYQQIISRLFHRHGGPGP 559
PEL V R + + AP VA LP Q+ + R P
Sbjct: 825 PAYTPELGLVPRSSPQHGVVSSPYVGVGPAPPVAGLPSAPPPQFSGPELAMAVR---PAT 881
Query: 560 GGPEPELSPITEGSEARAGP-PAPAPPA-PIPPPAP 593
+ +PI + R P PAP PP P+PPP P
Sbjct: 882 TTVDSIQAPIPSHTAPRPNPTPAPPPPCFPVPPPQP 917
Score = 40.4 bits (93), Expect = 0.007
Identities = 43/161 (26%), Positives = 55/161 (34%), Gaps = 29/161 (18%)
Query: 55 APP----GPQAGPPSRPPRYSSSSIPEPFGSRGSPRKAATDGADTPFGRSESAPTLHPYS 110
APP GP+ RP + SI P S +PR T P P P
Sbjct: 863 APPPQFSGPELAMAVRPATTTVDSIQAPIPSHTAPRPNPTPAPPPP-----CFPVPPPQP 917
Query: 111 PLSPKGRPSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRAPSPRPGPGPLRQQG 170
+P P+ + P+ Q + S A P PR +G P P P P P + G
Sbjct: 918 LPTPYTYPAGAKQPIPAQ-HHFSSGIPAGFPAPR--------IGPQPQPHPQPHPSQAFG 968
Query: 171 PPTPFDFLGRAGSPRGSPLAEGPQAFFPERGPSPRPPATAY 211
P P PL FP + P PP + Y
Sbjct: 969 P-----------QPPQQPLPLQHPHLFPPQAPGLLPPQSPY 998
Score = 35.8 bits (81), Expect = 0.17
Identities = 25/79 (31%), Positives = 31/79 (39%), Gaps = 8/79 (10%)
Query: 402 PPPKLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPPVNEGPPKPPTELE 461
P P P P P+S P P P P + P P P+ PPV E P P
Sbjct: 1521 PGPAEPPGLPPASLPESTPIPSSSPPPLSSPLPEAPQPKEE----PPVPEAPSSGP---- 1572
Query: 462 PEPEIEGLLTPVLEAGDVD 480
P +E L + EA +D
Sbjct: 1573 PSSSLELLASLTPEAFSLD 1591
Score = 34.7 bits (78), Expect = 0.37
Identities = 43/147 (29%), Positives = 52/147 (35%), Gaps = 13/147 (8%)
Query: 54 PAPPGPQAGPPSRPPRYSSSSIPEPFGSRGSPRKAATDGADTPFGRSESAPTLHPYSPLS 113
P+P PQ PP P Y + P G + +P T + G+S +P L P S
Sbjct: 1037 PSPGPPQ--PPHPPLAYGPAPSTRPMGPQAAP---LTIRGPSSAGQSTPSPHLVPSPAPS 1091
Query: 114 PKGRPSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRAPSPRPGPGPLRQQGPPT 173
P P PR P P L R + S G SP G PL Q PT
Sbjct: 1092 PGPGPVPPRPPAAEPPPC---LRRGAAAADLLSSSPESQHGGTQSPGGGQ-PLLQ---PT 1144
Query: 174 PFDFLGRAGSPRGSPLAEGPQAFFPER 200
D P+ L E PER
Sbjct: 1145 KVD-AAEGRRPQALRLIERDPYEHPER 1170
Score = 32.7 bits (73), Expect = 1.4
Identities = 38/122 (31%), Positives = 49/122 (40%), Gaps = 32/122 (26%)
Query: 559 PGGPEPELSPITEGSEARAGPPAPAPPAPIPP-------PAPSQSSP------PEQPQSM 605
PGG E SP+ A P PA P +PP P PS S P PE PQ
Sbjct: 1510 PGGLE---SPV-------ASLPGPAEPPGLPPASLPESTPIPSSSPPPLSSPLPEAPQPK 1559
Query: 606 EMRSV--LRKAGSPRKARR--ARLNPLVLLLDAALTGELEVVQQAVKEMNDPSQPNEEGI 661
E V +G P + A L P LD++L G +Q + + N N +G+
Sbjct: 1560 EEPPVPEAPSSGPPSSSLELLASLTPEAFSLDSSLRG-----KQRMSKHNFLQAHNGQGL 1614
Query: 662 TA 663
A
Sbjct: 1615 RA 1616
Score = 30.0 bits (66), Expect = 9.2
Identities = 21/69 (30%), Positives = 28/69 (40%), Gaps = 18/69 (26%)
Query: 392 LPGSPLFTRAPPPKLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPPVNE 451
LP + L P P P P P P++ PQP+ +P P P+ P +
Sbjct: 1529 LPPASLPESTPIPSSSPPPLSSPLPEA-------PQPKEEP----PVPEAP-------SS 1570
Query: 452 GPPKPPTEL 460
GPP EL
Sbjct: 1571 GPPSSSLEL 1579
>gi|28626517 protein phosphatase 1 regulatory inhibitor subunit 16B
[Homo sapiens]
Length = 567
Score = 84.3 bits (207), Expect = 4e-16
Identities = 52/161 (32%), Positives = 78/161 (48%), Gaps = 3/161 (1%)
Query: 600 EQPQSMEMRSVLRKAGSPRKARRARLNPLVLLLDAALTGELEVVQQAVKEMNDPSQPNEE 659
EQ R RK + + ++ V LL+A+L + E V+ +K P NE+
Sbjct: 41 EQDLQHRKRKHERKRSTGGRRKKVSFEASVALLEASLRNDAEEVRYFLKNKVSPDLCNED 100
Query: 660 GITALHNAICGANYSIVDFLITAGANVNSPDSHGWTPLHCAASCNDTVICMALVQHGAAI 719
G+TALH IV L++ GANVN+ D+ WTPLH AA+C + LVQ+GA +
Sbjct: 101 GLTALHQCCIDNFEEIVKLLLSHGANVNAKDNELWTPLHAAATCGHINLVKILVQYGADL 160
Query: 720 FATTLSDGATAFEKC--DPYREGYADCATYLADVEQSMGLM 758
A SDG ++ C +P + C Y ++ + M
Sbjct: 161 LAVN-SDGNMPYDLCEDEPTLDVIETCMAYQGITQEKINEM 200
Score = 43.9 bits (102), Expect = 6e-04
Identities = 24/68 (35%), Positives = 31/68 (45%)
Query: 659 EGITALHNAICGANYSIVDFLITAGANVNSPDSHGWTPLHCAASCNDTVICMALVQHGAA 718
+G T LH A + L+ G V+ D GW PLH AA + LV HGA+
Sbjct: 228 QGATLLHIAGANGYLRAAELLLDHGVRVDVKDWDGWEPLHAAAFWGQMQMAELLVSHGAS 287
Query: 719 IFATTLSD 726
+ A T D
Sbjct: 288 LSARTSMD 295
>gi|14249672 protein phosphatase 1, regulatory (inhibitor) subunit
16A [Homo sapiens]
Length = 528
Score = 83.2 bits (204), Expect = 9e-16
Identities = 55/160 (34%), Positives = 81/160 (50%), Gaps = 12/160 (7%)
Query: 592 APSQSSPPEQPQSMEMRSVLRKAGSPRKARRARLNPLVLLLDAALTGELEVVQQAVKEMN 651
A + P E+P+ ++A S ++ P V+LL+AA +LE V+Q +
Sbjct: 44 AQGKKGPGERPR--------KEAASQGLLKQVLFPPSVVLLEAAARNDLEEVRQFLGSGV 95
Query: 652 DPSQPNEEGITALHNAICGANYSIVDFLITAGANVNSPDSHGWTPLHCAASCNDTVICMA 711
P NE+G+TALH +V L+ AGAN+N+ DS WTPLH AA+C +
Sbjct: 96 SPDLANEDGLTALHQCCIDDFREMVQQLLEAGANINACDSECWTPLHAAATCGHLHLVEL 155
Query: 712 LVQHGAAIFATTLSDGATAFEKCDPYREGYADC-ATYLAD 750
L+ GA + A +DG ++ CD E DC T +AD
Sbjct: 156 LIASGANLLAVN-TDGNMPYDLCDD--EQTLDCLETAMAD 192
Score = 45.1 bits (105), Expect = 3e-04
Identities = 26/87 (29%), Positives = 40/87 (45%)
Query: 640 LEVVQQAVKEMNDPSQPNEEGITALHNAICGANYSIVDFLITAGANVNSPDSHGWTPLHC 699
L+ ++ ++ D P + G T LH A L+ A++++ D GW PLH
Sbjct: 212 LDDIRSRLQAGADLHAPLDHGATLLHVAAANGFSEAAALLLEHRASLSAKDQDGWEPLHA 271
Query: 700 AASCNDTVICMALVQHGAAIFATTLSD 726
AA + LV HGA + A +L D
Sbjct: 272 AAYWGQVPLVELLVAHGADLNAKSLMD 298
>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
Length = 2217
Score = 79.3 bits (194), Expect = 1e-14
Identities = 149/606 (24%), Positives = 204/606 (33%), Gaps = 109/606 (17%)
Query: 54 PAPPGPQAGPPSRPPRYSSSSIPEPFGSRGSPRKAATDGADTPFGR-SESAPTLHPYSPL 112
P P P+A PP +S+ S + +T +D+ + S +L +P
Sbjct: 587 PEPEEPEADQHLLPPTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPS 646
Query: 113 SPKGRPSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRAPSPRPGPGPLRQQGPP 172
+ S P + + P + SL P G +G P+P P QQ P
Sbjct: 647 PAQCVCSPPVSEGPVLPQSLPSLGAYQQPTA----APGLPVGSVPAPACPPS--LQQHFP 700
Query: 173 TPFDFLGRAGSPRGSPLAEGPQAFFPERGPSPRPPATAYDAPASAFGSSLLGSGGSAFAP 232
P P +P+ GP P P +PP A P AP
Sbjct: 701 DPAMSFAPVLPPPSTPMPTGPGQPAP---PGQQPPPLAQPTPLP-----------QVLAP 746
Query: 233 PLRAQDDLTLRRRPPKAWNESDLDVAYEKKPSQTASYERLDVFAR--PASPSLQLLP--W 288
PP S + + KP Q L A+ P P + ++P
Sbjct: 747 QPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAP-LQPLAQVPPQMPPIPVVPPIT 805
Query: 289 RESSLDGLGGTGKDNLTSATLPRNYKVSPLASDRRSDAGSYRRSLGSAGPSGTLPRSWQP 348
+ +DGL D L +AT+P P+ + SL + P + Q
Sbjct: 806 PLAGIDGLPPALPD-LPTATVP------PVPPPQYFSPAVILPSLAAPLPPASPALPLQA 858
Query: 349 VSRIPMPPSSPQPRGAPRQRP-----IPLSMIFKLQNAFWEHGASRAMLPGSPLFTRA-- 401
V ++P PP +P P IPL + A ++ A LPG P++ A
Sbjct: 859 V-KLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFP 917
Query: 402 ----------------------PPPKLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAP 439
P P L PQP PQP PQP LPPQP PQ PT P
Sbjct: 918 QMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQ-PTRPP 976
Query: 440 Q---HPQQTWPPVNEGPPKPPTELEPEP-------EIEGLLTPVLEAGDVDEGPVARPLS 489
Q PQ PP PP+P + PEP + TP + P A ++
Sbjct: 977 QPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVA 1036
Query: 490 PTRLQPALPPEAQSVPELEEV-----ARVLAEIPRPLKR-RGSMEQAP---AVALPPTHK 540
+PP A P L EV +L + P L S++ P A LPP +
Sbjct: 1037 AQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANP 1096
Query: 541 KQYQQIISRLFHRHGGPGPGGPEPELSPITEGSEARAGPPAPAPPAPIPPPAPSQSSPPE 600
GGPG P P + E P+ SQ PP
Sbjct: 1097 P-----------LPGGPGIASPCPTVQLTVE---------------PVQEEQASQDKPPG 1130
Query: 601 QPQSME 606
PQS E
Sbjct: 1131 LPQSCE 1136
Score = 52.8 bits (125), Expect = 1e-06
Identities = 129/521 (24%), Positives = 190/521 (36%), Gaps = 94/521 (18%)
Query: 55 APPGPQAGPPSRPP---------RYSSSSIPEPFGSRGSPRKAATDGADTPFGRSESAPT 105
APP P A PS PP ++S++PEP S G TP G + T
Sbjct: 1379 APPAPLA--PSSPPVTALPQDGAAPATSTMPEPASGTASQ----AGGPGTPQGLTSELET 1432
Query: 106 LHPYSPLSPKGRPSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRAPSPRPGPGP 165
P + + PL +QP G +P P A +S R P P P P P
Sbjct: 1433 SQPLA--------ETHEAPLAVQPLVVGLAP--CTPAPEAASTRDASAPREPLPPPAPEP 1482
Query: 166 LRQQGPPTPFDFLGRAGSPRG-SPLAEGPQAFFPERGPSPRPPATAYDAPASAFGSSLLG 224
G P P G P P A G + + PSP T P SA S G
Sbjct: 1483 SPHSGTPQP-----ALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALESD--G 1535
Query: 225 SGGSAFAPPLRAQDDLTLRRRPPKAWNESDLDVAYEKKPSQTASYERLDVFARPASPSLQ 284
G PP D T+ K+ +E + Y++ +++ V +L+
Sbjct: 1536 EG----PPPRVGFVDSTI-----KSLDEKLRTLLYQEHVPTSSASAGTPVEVGDRDFTLE 1586
Query: 285 LLPWRESSLDGLGGTGKDNLTSATLPRNYKVS-----PLASDRRSDAGSYRRSLGSAGPS 339
L + + GG +L +P+ VS P +S+ R ++ G S
Sbjct: 1587 PLRGDQPRSEVCGG----DLALPPVPKE-AVSGRVQLPQPLVEKSELAPTRGAVMEQGTS 1641
Query: 340 GTL-----PRSW--------QPVSRIPMPPSSPQPRGAPRQRPIPLSMIFKLQNAFWEHG 386
++ PRS Q S + PS PQ A RP + + E G
Sbjct: 1642 SSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPA-FVRP---ARVEPTDRDGGEAG 1697
Query: 387 ASRAMLPGSPLFT---RAPPPKL-------QPQPQPQPQPQSQPQPQLP--PQPQTQPQT 434
S A P S + T +A P+ P+ +P+ Q S P + TQ +
Sbjct: 1698 ESSAEPPPSDMGTVGGQASHPQTLGARALGSPRKRPEQQDVSSPAKTVGRFSVVSTQDEW 1757
Query: 435 PTPAPQHPQQTWPP---VNEGPPKPPTEL-----EPEPEIEGLLTPVLEAGDVDEGPVAR 486
+P + + PP ++E P P +L + IE + + + DEGP AR
Sbjct: 1758 TLASPHSLRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSIEVGVGEPVSSDSGDEGPRAR 1817
Query: 487 PLSPTRLQPALPPEAQSVPELEEVARVLAEIPRPLKRRGSM 527
P P + Q +LP + V + A + RP R GS+
Sbjct: 1818 P--PVQKQASLPVSGSVAGDF--VKKATAFLQRP-SRAGSL 1853
Score = 52.0 bits (123), Expect = 2e-06
Identities = 84/310 (27%), Positives = 112/310 (36%), Gaps = 62/310 (20%)
Query: 316 SPLASDRRSDAGSYRR-SLGSAGPSGTLPRSWQPVSRIPMPPSSPQPRGAPRQRPIPLSM 374
S + SD +S S SL A PS PVS P+ P S GA
Sbjct: 622 STVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGA---------- 671
Query: 375 IFKLQNAFWEHGASRAMLPGSPLFTRAPPPKLQPQPQPQPQPQSQPQPQLPPQPQTQPQT 434
++ + LP + A PP LQ Q P P P LPP P
Sbjct: 672 --------YQQPTAAPGLPVGSVPAPACPPSLQ---QHFPDPAMSFAPVLPPPSTPMPTG 720
Query: 435 P-TPAPQHPQQTWPPVNEGPPKPPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRL 493
P PAP P Q PP+ + P P L P+P + L PV P ++ +P +L
Sbjct: 721 PGQPAP--PGQQPPPLAQPTPLPQV-LAPQPVVP--LQPVPPHLPPYLAPASQVGAPAQL 775
Query: 494 QPALPPEAQSVPELEEVARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHR 553
+P P+A P LA++P + P +PP I+ L
Sbjct: 776 KPLQMPQAPLQP--------LAQVPP--------QMPPIPVVPP---------ITPLAGI 810
Query: 554 HGGPG-----PGGPEPELSPITEGSEARAGPPAPAPPAPIPPPAPSQS----SPPEQPQS 604
G P P P + P S A P AP P P P Q+ PP P +
Sbjct: 811 DGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLA 870
Query: 605 MEMRSVLRKA 614
M R+++ A
Sbjct: 871 MPCRTIVPNA 880
Score = 46.2 bits (108), Expect = 1e-04
Identities = 48/179 (26%), Positives = 72/179 (40%), Gaps = 12/179 (6%)
Query: 432 PQTPTPAPQHPQQTWP-PVNEGPPKPPTELEP-EPEIEGLLTPVLEAGDV---DEGPVAR 486
P PAP+ P+ + P P++ PP+ + P + ++ P A GP
Sbjct: 1317 PVAEHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNP 1376
Query: 487 P-LSPTRLQPALPPEAQSVPELEEVARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQ 545
P P L P+ PP ++P+ + A + +P P S P T + + Q
Sbjct: 1377 PGAPPAPLAPSSPP-VTALPQ-DGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQ 1434
Query: 546 IISRLFHRHGGPGPGGP-EPELSPITEGSEARAGPPAPAPPAPIPPPAPSQSSPPEQPQ 603
++ H P P L+P T EA + A AP P+PPPAP S PQ
Sbjct: 1435 PLAET---HEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQ 1490
Score = 40.8 bits (94), Expect = 0.005
Identities = 69/283 (24%), Positives = 85/283 (30%), Gaps = 81/283 (28%)
Query: 338 PSGTLPRSWQPVSRIPMPPSSPQPRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLPGSPL 397
P P P S P+P SS P + P + K Q +F L L
Sbjct: 1317 PVAEHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSF---------LASQQL 1367
Query: 398 FTRAPPPKLQPQPQPQPQPQSQPQPQLPPQPQTQPQT---PTPAPQHPQQTWPPVNEGPP 454
++A P P P P S P PQ P T P PA Q G P
Sbjct: 1368 LSQAGPSN-PPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQA------GGP 1420
Query: 455 KPPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPALP-PEAQSVPELEEVARV 513
P L E E L + E P+A L P P PEA S +
Sbjct: 1421 GTPQGLTSELETSQPLA------ETHEAPLAVQPLVVGLAPCTPAPEAASTRDAS----- 1469
Query: 514 LAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPELSPITEGS 573
AP LPP P PE SP +
Sbjct: 1470 ----------------APREPLPP------------------------PAPEPSPHSGTP 1489
Query: 574 EARAGPPAPAPPAPI----------PPPAPSQSSPPEQPQSME 606
+ G PAP PA + P P + PP+ P ++E
Sbjct: 1490 QPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALE 1532
Score = 36.2 bits (82), Expect = 0.13
Identities = 57/227 (25%), Positives = 78/227 (34%), Gaps = 50/227 (22%)
Query: 394 GSPLFTRAPPPKLQPQPQPQPQPQSQPQPQLPPQPQTQ-----PQTPTPAPQHPQQTWPP 448
GSP R PP LQ Q Q QP P P +P+ P PT A +
Sbjct: 559 GSPDKARGPPVPLQVQVTYHAQA-GQPGPPEPEEPEADQHLLPPTLPTSATSLASDSTFD 617
Query: 449 VNEGPPKPPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPALPPEAQSVPELE 508
+G + + +L + +A V P P P LP QS+P L
Sbjct: 618 SGQGSTVYSDSQSSQQSV--MLGSLADAAPSPAQCVCSP--PVSEGPVLP---QSLPSLG 670
Query: 509 EVARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPELSP 568
+ A P+ GS+ PA A PP+ ++ + P+P +S
Sbjct: 671 AYQQPTAAPGLPV---GSV---PAPACPPSLQQHF------------------PDPAMS- 705
Query: 569 ITEGSEARAGPPAPAPPAPIP----PPAPSQSSPPEQPQSMEMRSVL 611
P P P P+P PAP PP Q + VL
Sbjct: 706 --------FAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVL 744
Score = 34.7 bits (78), Expect = 0.37
Identities = 67/238 (28%), Positives = 88/238 (36%), Gaps = 46/238 (19%)
Query: 240 LTLRRRPPKAWNESDL---DVAYEKKPSQTASYERLDVFARPASPSLQLLPWRESS--LD 294
L L PP+A +S ++ +++PS AS + L P P SS +
Sbjct: 1333 LPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPAPLAPSSPPVT 1392
Query: 295 GLGGTGKDNLTSATLPRNYKVSPLASDRRSDAGSYRRSLGSAGPSGTLPR--SWQPVSRI 352
L G TS T+P AS S AG G P G + QP++
Sbjct: 1393 ALPQDGAAPATS-TMPEP------ASGTASQAG------GPGTPQGLTSELETSQPLAET 1439
Query: 353 PMPPSSPQPR--GAPRQRPIPLSMIFKLQNAFWEHGASR-AMLPGSPLFTRAPPPKLQPQ 409
P + QP G P P E ++R A P PL PPP +P
Sbjct: 1440 HEAPLAVQPLVVGLAPCTPAP------------EAASTRDASAPREPL----PPPAPEPS 1483
Query: 410 PQP-QPQPQ-SQPQPQLPPQPQTQPQTPTPAPQHPQQTWPPVNEGPPKPPTELEPEPE 465
P PQP QP P LP + P P P V PP+PP+ LE + E
Sbjct: 1484 PHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPP--LGPTV---PPQPPSALESDGE 1536
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 78.6 bits (192), Expect = 2e-14
Identities = 107/414 (25%), Positives = 135/414 (32%), Gaps = 68/414 (16%)
Query: 54 PAPPGPQAGPPSRPPRYSSSSIPEPFGSRGSPRKAAT-DGADTPFGRSESAPTL--HPYS 110
P+PPG GPP + P P +G P + P G+ + P S
Sbjct: 51 PSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRS 110
Query: 111 PLSPKGRPSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRAPSPRPGPGPLRQQG 170
P SP G+P P P G+ + P P G G P P PG + QG
Sbjct: 111 PRSPPGKPQGP-------PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG--KPQG 161
Query: 171 PPTPFDFLGRAG-SPRGSPLAEGPQAFFPERGPSPRPPATAYDAPASAFGSSLLGSGGSA 229
PP D R+ SP G P PQ +GP P PP P G+
Sbjct: 162 PPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPP-PPGKPQGPPPQG------GNKPQG 214
Query: 230 FAPPLRAQDDLTLRRRPPKAWNESDLDVAYEKKPSQTASYERLDVFARPASPSLQLLPWR 289
PP + Q PP+ N+S + KP P P P
Sbjct: 215 PPPPGKPQGP------PPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP 268
Query: 290 ESSLDGLGGTGKDNLTSATLPRNYKVSPLASDRRSDAGSYRRSLGS--AGPSGTLPRSWQ 347
+ GG N P P GS RS S P G P+
Sbjct: 269 Q------GG----NKPQGPPPPGKPQGP-----PPQGGSKSRSSRSPPGKPQGPPPQGGN 313
Query: 348 PVSRIPMPPSSPQPRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLPGSPLFTRAPPPKLQ 407
P PP PQ G P Q G ++ P P + PPP+
Sbjct: 314 QPQGPPPPPGKPQ--GPPPQ------------------GGNKPQGPPPPGKPQGPPPQGG 353
Query: 408 PQPQPQPQPQSQPQPQLPPQPQTQPQTPTPA----PQHPQQTWPPVNEGPPKPP 457
+ + P +PQ P Q PQ P P PQ PQ +GPP+PP
Sbjct: 354 SKSRSARSPPGKPQGP-PQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPP 406
Score = 77.8 bits (190), Expect = 4e-14
Identities = 112/424 (26%), Positives = 144/424 (33%), Gaps = 63/424 (14%)
Query: 83 GSPRKAATDGADTPFGRSESAPTLHPYSPLSPKGRPSSPRTPLYLQPDAYGSLDRATSPR 142
G+P+ A G + P G P SP G+P P P G+ + P
Sbjct: 34 GNPQGAPPQGGNKPQG------------PPSPPGKPQGP-------PPQGGNQPQGPPPP 74
Query: 143 PRAFDGAGSSLGRAPSPRPGPGPLRQQGPPTPFDFLGRAGSPRGSPLAEGPQAFFPERGP 202
P G G P P PG + QGPP D SP G P PQ +GP
Sbjct: 75 PGKPQGPPPQGGNKPQGPPPPG--KPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGP 132
Query: 203 SPRPPATAYDAPASAFGSSLLGSGGSAFAPPLRAQDDLTLRRRPPKAWNESDLDVAYEKK 262
P PP P G+ PP + Q PP+ N+S + K
Sbjct: 133 PP-PPGKPQGPPPQG------GNKPQGPPPPGKPQGP------PPQGDNKSRSSRSPPGK 179
Query: 263 PSQTASYERLDVFARPASPSLQLLPWRESSLDGLGGTGKDNLTSATLPRNYKVSPLASDR 322
P P P G G + P + P D
Sbjct: 180 PQGPPPQGGNQPQGPPPPP---------GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDN 230
Query: 323 RSDAGSYRRSLGSAGPSGTLPRSWQPVSRIPMPPSSPQ---PRGAPR-QRPIPLSMIFKL 378
+S S R G P G P+ P PP PQ P+G + Q P P K
Sbjct: 231 KSQ--SARSPPGK--PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG---KP 283
Query: 379 QNAFWEHGASRAMLPGSPLFTRAPPPKLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPA 438
Q + G+ P + PPP+ QPQ P P +PQ PPQ +PQ P P
Sbjct: 284 QGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP-PPQGGNKPQGP-PP 341
Query: 439 PQHPQQTWPPVNEGPPKPPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPALP 498
P PQ P +G K + P + +G P + G+ +GP P QP P
Sbjct: 342 PGKPQ---GPPPQGGSKSRSARSPPGKPQG---PPQQEGNNPQGP-PPPAGGNPQQPQAP 394
Query: 499 PEAQ 502
P Q
Sbjct: 395 PAGQ 398
Score = 74.3 bits (181), Expect = 4e-13
Identities = 115/457 (25%), Positives = 145/457 (31%), Gaps = 95/457 (20%)
Query: 157 PSPRPGPGPLRQQGPPTPFDFLGRAGSPRGSPLAEGPQAFFPERGPSPRPPATAYDAPAS 216
P P G + QGPP+P G P+G P PQ +GP P P P
Sbjct: 36 PQGAPPQGGNKPQGPPSP------PGKPQGPP----PQGGNQPQGPPPPPGKPQGPPPQG 85
Query: 217 AFGSSLLGSGGSAFAPPLRAQDDLTLRRRPPKAWNESDLDVAYEKKPSQTASYERLDVFA 276
G PP + + R P K + P Q +
Sbjct: 86 GNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKP----------QGPPPQGGN-------- 127
Query: 277 RPASPSLQLLPWRESSLDGLGGTGKDNLTSATLPRNYKVSPLASDRRSDAGSYRRSLGSA 336
+P P P G G + P + P D +S R S
Sbjct: 128 QPQGP-----PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKS-----RSSRSPP 177
Query: 337 G-PSGTLPRSWQPVSRIPMPPSSPQPRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLPGS 395
G P G P+ P PP PQ G P Q G ++ P
Sbjct: 178 GKPQGPPPQGGNQPQGPPPPPGKPQ--GPPPQ------------------GGNKPQGPPP 217
Query: 396 PLFTRAPPPKLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPPVNEGPPK 455
P + PPP+ + Q P +PQ PPQ QPQ P P P PQ P P
Sbjct: 218 PGKPQGPPPQGDNKSQSARSPPGKPQGP-PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQG 276
Query: 456 PPTELEPEPEIEGLLTPVLEAGDVDEG---PVARPLSPTRL---QPALPPEAQSVPELEE 509
PP +P+ P + G P +P P QP PP P+
Sbjct: 277 PPPPGKPQG-------PPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ--- 326
Query: 510 VARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPELSPI 569
P + G+ Q P PP K Q R PG +P+ P
Sbjct: 327 ---------GPPPQGGNKPQGP----PPPGKPQGPPPQGGSKSRSARSPPG--KPQGPPQ 371
Query: 570 TEGSEARAGPPAPA---PPAPIPPPAPSQSSPPEQPQ 603
EG+ + GPP PA P P PPA PP PQ
Sbjct: 372 QEGNNPQ-GPPPPAGGNPQQPQAPPAGQPQGPPRPPQ 407
Score = 73.2 bits (178), Expect = 9e-13
Identities = 88/319 (27%), Positives = 118/319 (36%), Gaps = 62/319 (19%)
Query: 332 SLGSAGPSGTLPRSWQPVSRIPMPPSSPQ---PRGA--PRQRPIPLSMIFKLQNAFWEHG 386
SL + P G P+ P PP PQ P+G P+ P P K Q G
Sbjct: 30 SLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPG---KPQGPP-PQG 85
Query: 387 ASRAMLPGSPLFTRAPPPK-------LQPQPQPQ-PQPQSQPQPQLPPQPQTQPQTPTPA 438
++ P P + PPP+ P +PQ P PQ QPQ PP P +PQ P P
Sbjct: 86 GNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 145
Query: 439 PQHPQQTWPPVN--EGPP-----KPPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPT 491
+ Q PP +GPP K + P + +G P + G+ +GP P P
Sbjct: 146 GGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQG---PPPQGGNQPQGPPPPPGKP- 201
Query: 492 RLQPALPPEAQSVPELEEVARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLF 551
PP+ + P+ P P K +G PP + Q S
Sbjct: 202 ---QGPPPQGGNKPQ---------GPPPPGKPQGP---------PPQGDNKSQSARSPPG 240
Query: 552 HRHGGPGPGGPEPE---------LSPITEGSEARAGPPAPAPPAPIPPPAPSQS----SP 598
G P GG +P+ P +G GPP P P PP S+S SP
Sbjct: 241 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSP 300
Query: 599 PEQPQSMEMRSVLRKAGSP 617
P +PQ + + G P
Sbjct: 301 PGKPQGPPPQGGNQPQGPP 319
Score = 68.6 bits (166), Expect = 2e-11
Identities = 84/310 (27%), Positives = 109/310 (35%), Gaps = 70/310 (22%)
Query: 338 PSGTLPRSWQPVSRIPMPPSSPQPRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLPGSPL 397
P G P+ P PP PQ G P Q G ++ P P
Sbjct: 118 PQGPPPQGGNQPQGPPPPPGKPQ--GPPPQ------------------GGNKPQGPPPPG 157
Query: 398 FTRAPPPK--------LQPQPQPQ-PQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPP 448
+ PPP+ P +PQ P PQ QPQ PP P +PQ P P + Q PP
Sbjct: 158 KPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP 217
Query: 449 VN--EGPP-----KPPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPALPPEA 501
+GPP K + P + +G P + G+ +GP P P PP+
Sbjct: 218 PGKPQGPPPQGDNKSQSARSPPGKPQG---PPPQGGNQPQGPPPPPGKPQ----GPPPQG 270
Query: 502 QSVPELEEVARVLAEIPRPLKRRGSMEQAPAVALP---PTHKKQYQQIISRLFHRHGGPG 558
+ P+ P P K +G Q + + P K Q GG
Sbjct: 271 GNKPQGP---------PPPGKPQGPPPQGGSKSRSSRSPPGKPQGPP-------PQGGNQ 314
Query: 559 PGGPEPE----LSPITEGSEARAGPPAPAPPAPIPPPAPSQS----SPPEQPQSMEMRSV 610
P GP P P +G GPP P P PP S+S SPP +PQ +
Sbjct: 315 PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEG 374
Query: 611 LRKAGSPRKA 620
G P A
Sbjct: 375 NNPQGPPPPA 384
Score = 58.9 bits (141), Expect = 2e-08
Identities = 66/243 (27%), Positives = 87/243 (35%), Gaps = 33/243 (13%)
Query: 395 SPLFTRAPPPKLQPQPQPQPQ-PQSQP-QPQ-LPPQPQTQPQTPTPAPQHPQQTWPPVNE 451
SP P PQ +PQ P S P +PQ PPQ QPQ P P P PQ P
Sbjct: 28 SPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 87
Query: 452 GPPKPPTELEPEPEIEGLLTPVLEAGDVDEGPVAR-PLSPTRLQPALPPEAQSVPELEEV 510
P PP +P+ G +G +R P SP PP+ + P+
Sbjct: 88 KPQGPPPPGKPQ-------------GPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPP 134
Query: 511 ARVLAEIPRPL---KRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPE-- 565
+ P P K +G PP + + S G P GG +P+
Sbjct: 135 PPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGP 194
Query: 566 -------LSPITEGSEARAGPPAPAPPAPIPPPAPSQS----SPPEQPQSMEMRSVLRKA 614
P +G GPP P P PP ++S SPP +PQ + +
Sbjct: 195 PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQ 254
Query: 615 GSP 617
G P
Sbjct: 255 GPP 257
Score = 52.8 bits (125), Expect = 1e-06
Identities = 50/197 (25%), Positives = 64/197 (32%), Gaps = 8/197 (4%)
Query: 53 SPAPPGPQAGPPSRPPRYSSSSIPEPFGSRGSPRKAAT-DGADTPFGRSESAPTLHPYSP 111
S +PPG GPP + P P +G P + P G+ + P
Sbjct: 173 SRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKS 232
Query: 112 LSPKGRPSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRAPSPRPGPGPLRQQGP 171
S + P P+ P P G+ + P P G G P P PG + QGP
Sbjct: 233 QSARSPPGKPQGP----PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG--KPQGP 286
Query: 172 PTPFDFLGRAG-SPRGSPLAEGPQAFFPERGPSPRPPATAYDAPASAFGSSLLGSGGSAF 230
P R+ SP G P PQ +GP P P P G
Sbjct: 287 PPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQ 346
Query: 231 APPLRAQDDLTLRRRPP 247
PP + R PP
Sbjct: 347 GPPPQGGSKSRSARSPP 363
>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 78.2 bits (191), Expect = 3e-14
Identities = 136/580 (23%), Positives = 194/580 (33%), Gaps = 86/580 (14%)
Query: 53 SPAPP-GPQAGPPSRP----PRYSSSSIPEPFGSRGSPRKAATDGADTPFGRSESAPTLH 107
SPA P G GP P PR P P + P + A + G ++ AP+
Sbjct: 279 SPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRL 338
Query: 108 PYSP---LSPKGRPSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRAPSPRPGPG 164
P P + P + R P +PD G L PR + RA +P P P
Sbjct: 339 PLPPSFHIRPASQVYPDRAP---EPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPP 395
Query: 165 ------PLRQQGPPTP-----FDFLGRAGSPRGSPLAEGPQAFFPERGPSPRPPA---TA 210
PL PP P +A P + P++ P P P PP+ TA
Sbjct: 396 LPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAG-FTKTPKSSSPALKPKPNPPSPENTA 454
Query: 211 YDAPASAFGSSLLGSGGSAFAPPL---RAQDDLTLRRRPPKAWNESDLDVAYEKKPSQTA 267
AP S + + A L R +D R P +S + P
Sbjct: 455 SSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLP---- 510
Query: 268 SYERLDVFARPASPSLQLLPWRESSLDGLGGTGKDNLTSATLPRNYKVSPLASDRRSDAG 327
E+ + + PA + +P E SL G T + S TLP V + D + +
Sbjct: 511 --EKETLLSLPAKDTPPGVP--EKSLGGSSLTETEAAPSLTLP---SVDYIPQDSPTPSV 563
Query: 328 SYRRSLGSAGPSGTLPRSWQPVSRIPMPPSSPQPRGAPRQRPIPLSMIFKLQNAFWEHGA 387
R+ A S + +P I P P+ G E+GA
Sbjct: 564 RQIRNELEARLSSAAEKEAKP--SIGSLPPKPRLEGG----------------RICENGA 605
Query: 388 SRAMLPGSPLFTRAPPPKLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWP 447
L P+ PP P QP++ P +PP+ +P P A P T P
Sbjct: 606 DDDKL-SKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWP-ATPP 663
Query: 448 PVNEGP---------PKPPTELEPEPEIEGLLTPVLEA-----GDVDEGPVARPLSPTRL 493
GP P P + P I T + + D GP +P P
Sbjct: 664 KATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQ 723
Query: 494 QPALPPEAQSVPELEEVARVLAEIPR-----PLKRRGSMEQAPAVALPPTHKKQYQQ--- 545
+ + P +A+ E R+ + R P K + P + P H+ +
Sbjct: 724 EVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVA 783
Query: 546 IISRLFHRHGGPGPGGPEPELSPITEGSEARAGPPAPAPP 585
++ R G GPG P + E A PPA A P
Sbjct: 784 VVMPTLARGGAAGPGEP----VEVKEPPGLPAKPPASAQP 819
Score = 64.3 bits (155), Expect = 4e-10
Identities = 76/303 (25%), Positives = 99/303 (32%), Gaps = 51/303 (16%)
Query: 352 IPMPPSSPQPRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLPGSPLFTRAPPPKLQPQPQ 411
IP PP P P G P+ P + S A P L PPP + P P
Sbjct: 139 IPPPPPGPAP-GPPQDISEPPG------GSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPP 191
Query: 412 PQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPPVNEGPPKPPTELEPEPEIEGLLT 471
P + S P P T P PAP PP P PP P L
Sbjct: 192 PVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFP 251
Query: 472 P----------VLEAGDVDEGPVARPLSPT---------------------RLQPALPPE 500
P L + + P SP ++ P P
Sbjct: 252 PGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVR 311
Query: 501 AQSVPELEEVARVLAEIPRPLKRRGSMEQAPA-VALPPT-HKKQYQQIISRLFHRHGGPG 558
S+P E E PR K G+ ++AP+ + LPP+ H + Q+ PG
Sbjct: 312 TSSIPVQE-----AQEAPR--KEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPG 364
Query: 559 ----PGGPEPELSPITEGSEARAGPPAPAPPAPIPPPAPSQSSPPEQPQSMEMRSVLRKA 614
P L ++ RAG P PAPP P P P +PP P + + + A
Sbjct: 365 ELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAA 424
Query: 615 GSP 617
P
Sbjct: 425 HPP 427
Score = 63.2 bits (152), Expect = 1e-09
Identities = 154/661 (23%), Positives = 223/661 (33%), Gaps = 120/661 (18%)
Query: 54 PAPPGPQAGPP---SRPPRYSSSSIPEPFGSRGSPRKAATDGADTPFGRSESAPTLHPYS 110
P PPGP GPP S PP S +P P + P + P P L S
Sbjct: 141 PPPPGPAPGPPQDISEPP--GGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALS 198
Query: 111 PLSPKGRPSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRAPSPRPGPGPLRQQG 170
P PS P P ++ P P AF L P P P P P
Sbjct: 199 PPHTLSSPSIPTPPDFIPP-----------APPLAF------LAPPPPPVPAPAP---PA 238
Query: 171 PPTPFDFLGRAGSPRGSPLAEGPQAFFPERGPSPR--PPATAYDAPASAFGSSLLGSGGS 228
P +P R P G + A + + R PP + + SA G +
Sbjct: 239 PASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPN------- 291
Query: 229 AFAPPLRAQDDLTLRRRPPKAWNESDLDV-AYEKKPSQTASYERLDVFARPASPSLQLLP 287
P + + PP S + V ++ P + + P PS + P
Sbjct: 292 ---PEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRP 348
Query: 288 WRESSLDGLGGTGKDNLTSATLPRNYKVSPLASDRRSDAGSYRRSLGSAGPSGTLPRSWQ 347
+ D AT P SP +S A G+ P+ LP
Sbjct: 349 ASQVYPDRAPEPDCPGELKATAP----ASPRLGQSQSQAD---ERAGTPPPAPPLP---P 398
Query: 348 PVSRIPMPPSSPQPRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLPGSPLFTRAP---PP 404
P +P PP+ P P AP P+P A +A P + FT+ P P
Sbjct: 399 PAPPLP-PPAPPLPPAAP---PLPC--------------AQKAAHPPAG-FTKTPKSSSP 439
Query: 405 KLQPQPQPQPQPQ----SQPQPQLPPQPQTQPQTPTPA---PQHPQQTWPPVNEGPPKPP 457
L+P+P P P P+ S P P + + A + + GP P
Sbjct: 440 ALKPKPNP-PSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAP 498
Query: 458 TELEPE-----PEIEGLLTPVLEAGDVDEGPVAR-----PLSPTRLQPALP-PEAQSVPE 506
E + PE E LL+ L A D G + L+ T P+L P +P+
Sbjct: 499 QSKEGKKGPRLPEKETLLS--LPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQ 556
Query: 507 ---LEEVARVLAEIPRPLKRRGSMEQAPAV-ALPPTHKKQYQQI---------ISRLFHR 553
V ++ E+ L E P++ +LPP + + +I +S+ +
Sbjct: 557 DSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAK 616
Query: 554 HGGPGPGGPEPELSPITEGSEARAGPPAPAPPAPIPPPA-------PSQSSPPEQP--QS 604
+ P P S + A PP P IPP A P + P P +
Sbjct: 617 NLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATPLKAT 676
Query: 605 MEMRSVLRKAGSPRKARRARLNP-----LVLLLDAALTGELEVVQQAVKEMNDPSQPNEE 659
+ L+ P A A P L+ D+ G+ E + A +E++ PSQ E
Sbjct: 677 SGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPE--KPASQEVSTPSQARGE 734
Query: 660 G 660
G
Sbjct: 735 G 735
Score = 61.2 bits (147), Expect = 4e-09
Identities = 118/491 (24%), Positives = 165/491 (33%), Gaps = 77/491 (15%)
Query: 127 LQPDAYGSLDRATSPRPRAFDG---------AGSSLGRAPSPRPGPGPLRQQGPPTPFDF 177
L+P YG P P G GS L PS P P PL + PP P
Sbjct: 128 LRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPP--- 184
Query: 178 LGRAGSPRGSPLAEGPQAFFPERGPS-PRPPATAYDAPASAFGSSLLGSGGSAFAPPLRA 236
+ +P P+ E PS P PP AP AF + + P +
Sbjct: 185 ---SMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPAS 241
Query: 237 QDDLTLRRRPPKAWNESDLDVAYEKKPSQTASYERLDVFARPASPSLQLLPWRESSLDGL 296
+ R PP + DVA + ++ + P SP+ E L
Sbjct: 242 PHTVGTRLFPPGGVTKWKSDVALNGRQAEATR------ASPPRSPA-------EPKGSAL 288
Query: 297 GGTGKDNLTSATLPRNYKVSPLASDRRSDAGSYRRSLGSAGPSGTLPRSWQPVSRIPMPP 356
G + +L T PR++KV P R S G ++ SR+P+PP
Sbjct: 289 GPNPEPHL---TFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKA---PSRLPLPP 342
Query: 357 S---SPQPRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLPGSPLFTRAPPPKLQPQPQPQ 413
S P + P + P P G +A P SP Q Q Q
Sbjct: 343 SFHIRPASQVYPDRAPEPDC-----------PGELKATAPASPRL---------GQSQSQ 382
Query: 414 PQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWP-PVNEGPPKPPTELEPEPEIEGLLTP 472
++ P PP P P P PAP P P P + PP P+ +P
Sbjct: 383 ADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSS---SP 439
Query: 473 VLEAGDVDEGPVARPLSPTRLQPALPPEAQSVPELEEVARVLAEI---PRPLKRRGSMEQ 529
L+ P P SP + P + + ++E++ LA R R S
Sbjct: 440 ALK-------PKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRP 492
Query: 530 APAVALPPTHKKQYQQIISR---LFHRHGGPGPGGPEPELSPITEGSEARAGPPAPAPPA 586
P VA K+ ++ + L PG PE L + +E A P P
Sbjct: 493 GPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGG-SSLTETEAAPSLTLPSV 551
Query: 587 P-IPPPAPSQS 596
IP +P+ S
Sbjct: 552 DYIPQDSPTPS 562
Score = 47.8 bits (112), Expect = 4e-05
Identities = 70/236 (29%), Positives = 87/236 (36%), Gaps = 61/236 (25%)
Query: 406 LQPQPQPQPQPQSQPQPQLPPQPQTQPQ--TPTPAPQHPQQTWPPVNEGPPKPPTELEPE 463
L P P P P P PPQ ++P +P P+P PP+ PP PP+ P
Sbjct: 138 LIPPPPPGPAPG-------PPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPP 190
Query: 464 PEIEGLLTPVLEAGDVDEGPVARPLSP--TRLQPALPPEAQSVPELEEVARVLAEIPRPL 521
P PVLEA LSP T P++P +P +A LA P P+
Sbjct: 191 P-------PVLEA-----------LSPPHTLSSPSIPTPPDFIPPAPPLA-FLAPPPPPV 231
Query: 522 KRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPELSPIT----EGSEARA 577
PA A P T + +RLF PGG S + + RA
Sbjct: 232 ----PAPAPPAPASPHT-------VGTRLF------PPGGVTKWKSDVALNGRQAEATRA 274
Query: 578 GPP-APAPP---APIPPPAP------SQSSPPEQPQSMEMRSVLRKAGSPRKARRA 623
PP +PA P A P P P S PP P V +PRK A
Sbjct: 275 SPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGA 330
>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 78.2 bits (191), Expect = 3e-14
Identities = 136/580 (23%), Positives = 194/580 (33%), Gaps = 86/580 (14%)
Query: 53 SPAPP-GPQAGPPSRP----PRYSSSSIPEPFGSRGSPRKAATDGADTPFGRSESAPTLH 107
SPA P G GP P PR P P + P + A + G ++ AP+
Sbjct: 279 SPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRL 338
Query: 108 PYSP---LSPKGRPSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRAPSPRPGPG 164
P P + P + R P +PD G L PR + RA +P P P
Sbjct: 339 PLPPSFHIRPASQVYPDRAP---EPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPP 395
Query: 165 ------PLRQQGPPTP-----FDFLGRAGSPRGSPLAEGPQAFFPERGPSPRPPA---TA 210
PL PP P +A P + P++ P P P PP+ TA
Sbjct: 396 LPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAG-FTKTPKSSSPALKPKPNPPSPENTA 454
Query: 211 YDAPASAFGSSLLGSGGSAFAPPL---RAQDDLTLRRRPPKAWNESDLDVAYEKKPSQTA 267
AP S + + A L R +D R P +S + P
Sbjct: 455 SSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLP---- 510
Query: 268 SYERLDVFARPASPSLQLLPWRESSLDGLGGTGKDNLTSATLPRNYKVSPLASDRRSDAG 327
E+ + + PA + +P E SL G T + S TLP V + D + +
Sbjct: 511 --EKETLLSLPAKDTPPGVP--EKSLGGSSLTETEAAPSLTLP---SVDYIPQDSPTPSV 563
Query: 328 SYRRSLGSAGPSGTLPRSWQPVSRIPMPPSSPQPRGAPRQRPIPLSMIFKLQNAFWEHGA 387
R+ A S + +P I P P+ G E+GA
Sbjct: 564 RQIRNELEARLSSAAEKEAKP--SIGSLPPKPRLEGG----------------RICENGA 605
Query: 388 SRAMLPGSPLFTRAPPPKLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWP 447
L P+ PP P QP++ P +PP+ +P P A P T P
Sbjct: 606 DDDKL-SKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWP-ATPP 663
Query: 448 PVNEGP---------PKPPTELEPEPEIEGLLTPVLEA-----GDVDEGPVARPLSPTRL 493
GP P P + P I T + + D GP +P P
Sbjct: 664 KATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQ 723
Query: 494 QPALPPEAQSVPELEEVARVLAEIPR-----PLKRRGSMEQAPAVALPPTHKKQYQQ--- 545
+ + P +A+ E R+ + R P K + P + P H+ +
Sbjct: 724 EVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVA 783
Query: 546 IISRLFHRHGGPGPGGPEPELSPITEGSEARAGPPAPAPP 585
++ R G GPG P + E A PPA A P
Sbjct: 784 VVMPTLARGGAAGPGEP----VEVKEPPGLPAKPPASAQP 819
Score = 64.3 bits (155), Expect = 4e-10
Identities = 76/303 (25%), Positives = 99/303 (32%), Gaps = 51/303 (16%)
Query: 352 IPMPPSSPQPRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLPGSPLFTRAPPPKLQPQPQ 411
IP PP P P G P+ P + S A P L PPP + P P
Sbjct: 139 IPPPPPGPAP-GPPQDISEPPG------GSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPP 191
Query: 412 PQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPPVNEGPPKPPTELEPEPEIEGLLT 471
P + S P P T P PAP PP P PP P L
Sbjct: 192 PVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFP 251
Query: 472 P----------VLEAGDVDEGPVARPLSPT---------------------RLQPALPPE 500
P L + + P SP ++ P P
Sbjct: 252 PGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVR 311
Query: 501 AQSVPELEEVARVLAEIPRPLKRRGSMEQAPA-VALPPT-HKKQYQQIISRLFHRHGGPG 558
S+P E E PR K G+ ++AP+ + LPP+ H + Q+ PG
Sbjct: 312 TSSIPVQE-----AQEAPR--KEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPG 364
Query: 559 ----PGGPEPELSPITEGSEARAGPPAPAPPAPIPPPAPSQSSPPEQPQSMEMRSVLRKA 614
P L ++ RAG P PAPP P P P +PP P + + + A
Sbjct: 365 ELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAA 424
Query: 615 GSP 617
P
Sbjct: 425 HPP 427
Score = 63.2 bits (152), Expect = 1e-09
Identities = 154/661 (23%), Positives = 223/661 (33%), Gaps = 120/661 (18%)
Query: 54 PAPPGPQAGPP---SRPPRYSSSSIPEPFGSRGSPRKAATDGADTPFGRSESAPTLHPYS 110
P PPGP GPP S PP S +P P + P + P P L S
Sbjct: 141 PPPPGPAPGPPQDISEPP--GGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALS 198
Query: 111 PLSPKGRPSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRAPSPRPGPGPLRQQG 170
P PS P P ++ P P AF L P P P P P
Sbjct: 199 PPHTLSSPSIPTPPDFIPP-----------APPLAF------LAPPPPPVPAPAP---PA 238
Query: 171 PPTPFDFLGRAGSPRGSPLAEGPQAFFPERGPSPR--PPATAYDAPASAFGSSLLGSGGS 228
P +P R P G + A + + R PP + + SA G +
Sbjct: 239 PASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPN------- 291
Query: 229 AFAPPLRAQDDLTLRRRPPKAWNESDLDV-AYEKKPSQTASYERLDVFARPASPSLQLLP 287
P + + PP S + V ++ P + + P PS + P
Sbjct: 292 ---PEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRP 348
Query: 288 WRESSLDGLGGTGKDNLTSATLPRNYKVSPLASDRRSDAGSYRRSLGSAGPSGTLPRSWQ 347
+ D AT P SP +S A G+ P+ LP
Sbjct: 349 ASQVYPDRAPEPDCPGELKATAP----ASPRLGQSQSQAD---ERAGTPPPAPPLP---P 398
Query: 348 PVSRIPMPPSSPQPRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLPGSPLFTRAP---PP 404
P +P PP+ P P AP P+P A +A P + FT+ P P
Sbjct: 399 PAPPLP-PPAPPLPPAAP---PLPC--------------AQKAAHPPAG-FTKTPKSSSP 439
Query: 405 KLQPQPQPQPQPQ----SQPQPQLPPQPQTQPQTPTPA---PQHPQQTWPPVNEGPPKPP 457
L+P+P P P P+ S P P + + A + + GP P
Sbjct: 440 ALKPKPNP-PSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAP 498
Query: 458 TELEPE-----PEIEGLLTPVLEAGDVDEGPVAR-----PLSPTRLQPALP-PEAQSVPE 506
E + PE E LL+ L A D G + L+ T P+L P +P+
Sbjct: 499 QSKEGKKGPRLPEKETLLS--LPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQ 556
Query: 507 ---LEEVARVLAEIPRPLKRRGSMEQAPAV-ALPPTHKKQYQQI---------ISRLFHR 553
V ++ E+ L E P++ +LPP + + +I +S+ +
Sbjct: 557 DSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAK 616
Query: 554 HGGPGPGGPEPELSPITEGSEARAGPPAPAPPAPIPPPA-------PSQSSPPEQP--QS 604
+ P P S + A PP P IPP A P + P P +
Sbjct: 617 NLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATPLKAT 676
Query: 605 MEMRSVLRKAGSPRKARRARLNP-----LVLLLDAALTGELEVVQQAVKEMNDPSQPNEE 659
+ L+ P A A P L+ D+ G+ E + A +E++ PSQ E
Sbjct: 677 SGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPE--KPASQEVSTPSQARGE 734
Query: 660 G 660
G
Sbjct: 735 G 735
Score = 61.2 bits (147), Expect = 4e-09
Identities = 118/491 (24%), Positives = 165/491 (33%), Gaps = 77/491 (15%)
Query: 127 LQPDAYGSLDRATSPRPRAFDG---------AGSSLGRAPSPRPGPGPLRQQGPPTPFDF 177
L+P YG P P G GS L PS P P PL + PP P
Sbjct: 128 LRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPP--- 184
Query: 178 LGRAGSPRGSPLAEGPQAFFPERGPS-PRPPATAYDAPASAFGSSLLGSGGSAFAPPLRA 236
+ +P P+ E PS P PP AP AF + + P +
Sbjct: 185 ---SMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPAS 241
Query: 237 QDDLTLRRRPPKAWNESDLDVAYEKKPSQTASYERLDVFARPASPSLQLLPWRESSLDGL 296
+ R PP + DVA + ++ + P SP+ E L
Sbjct: 242 PHTVGTRLFPPGGVTKWKSDVALNGRQAEATR------ASPPRSPA-------EPKGSAL 288
Query: 297 GGTGKDNLTSATLPRNYKVSPLASDRRSDAGSYRRSLGSAGPSGTLPRSWQPVSRIPMPP 356
G + +L T PR++KV P R S G ++ SR+P+PP
Sbjct: 289 GPNPEPHL---TFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKA---PSRLPLPP 342
Query: 357 S---SPQPRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLPGSPLFTRAPPPKLQPQPQPQ 413
S P + P + P P G +A P SP Q Q Q
Sbjct: 343 SFHIRPASQVYPDRAPEPDC-----------PGELKATAPASPRL---------GQSQSQ 382
Query: 414 PQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWP-PVNEGPPKPPTELEPEPEIEGLLTP 472
++ P PP P P P PAP P P P + PP P+ +P
Sbjct: 383 ADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSS---SP 439
Query: 473 VLEAGDVDEGPVARPLSPTRLQPALPPEAQSVPELEEVARVLAEI---PRPLKRRGSMEQ 529
L+ P P SP + P + + ++E++ LA R R S
Sbjct: 440 ALK-------PKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRP 492
Query: 530 APAVALPPTHKKQYQQIISR---LFHRHGGPGPGGPEPELSPITEGSEARAGPPAPAPPA 586
P VA K+ ++ + L PG PE L + +E A P P
Sbjct: 493 GPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGG-SSLTETEAAPSLTLPSV 551
Query: 587 P-IPPPAPSQS 596
IP +P+ S
Sbjct: 552 DYIPQDSPTPS 562
Score = 47.8 bits (112), Expect = 4e-05
Identities = 70/236 (29%), Positives = 87/236 (36%), Gaps = 61/236 (25%)
Query: 406 LQPQPQPQPQPQSQPQPQLPPQPQTQPQ--TPTPAPQHPQQTWPPVNEGPPKPPTELEPE 463
L P P P P P PPQ ++P +P P+P PP+ PP PP+ P
Sbjct: 138 LIPPPPPGPAPG-------PPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPP 190
Query: 464 PEIEGLLTPVLEAGDVDEGPVARPLSP--TRLQPALPPEAQSVPELEEVARVLAEIPRPL 521
P PVLEA LSP T P++P +P +A LA P P+
Sbjct: 191 P-------PVLEA-----------LSPPHTLSSPSIPTPPDFIPPAPPLA-FLAPPPPPV 231
Query: 522 KRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPELSPIT----EGSEARA 577
PA A P T + +RLF PGG S + + RA
Sbjct: 232 ----PAPAPPAPASPHT-------VGTRLF------PPGGVTKWKSDVALNGRQAEATRA 274
Query: 578 GPP-APAPP---APIPPPAP------SQSSPPEQPQSMEMRSVLRKAGSPRKARRA 623
PP +PA P A P P P S PP P V +PRK A
Sbjct: 275 SPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGA 330
>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo
sapiens]
Length = 1188
Score = 78.2 bits (191), Expect = 3e-14
Identities = 136/580 (23%), Positives = 194/580 (33%), Gaps = 86/580 (14%)
Query: 53 SPAPP-GPQAGPPSRP----PRYSSSSIPEPFGSRGSPRKAATDGADTPFGRSESAPTLH 107
SPA P G GP P PR P P + P + A + G ++ AP+
Sbjct: 279 SPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRL 338
Query: 108 PYSP---LSPKGRPSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRAPSPRPGPG 164
P P + P + R P +PD G L PR + RA +P P P
Sbjct: 339 PLPPSFHIRPASQVYPDRAP---EPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPP 395
Query: 165 ------PLRQQGPPTP-----FDFLGRAGSPRGSPLAEGPQAFFPERGPSPRPPA---TA 210
PL PP P +A P + P++ P P P PP+ TA
Sbjct: 396 LPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAG-FTKTPKSSSPALKPKPNPPSPENTA 454
Query: 211 YDAPASAFGSSLLGSGGSAFAPPL---RAQDDLTLRRRPPKAWNESDLDVAYEKKPSQTA 267
AP S + + A L R +D R P +S + P
Sbjct: 455 SSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLP---- 510
Query: 268 SYERLDVFARPASPSLQLLPWRESSLDGLGGTGKDNLTSATLPRNYKVSPLASDRRSDAG 327
E+ + + PA + +P E SL G T + S TLP V + D + +
Sbjct: 511 --EKETLLSLPAKDTPPGVP--EKSLGGSSLTETEAAPSLTLP---SVDYIPQDSPTPSV 563
Query: 328 SYRRSLGSAGPSGTLPRSWQPVSRIPMPPSSPQPRGAPRQRPIPLSMIFKLQNAFWEHGA 387
R+ A S + +P I P P+ G E+GA
Sbjct: 564 RQIRNELEARLSSAAEKEAKP--SIGSLPPKPRLEGG----------------RICENGA 605
Query: 388 SRAMLPGSPLFTRAPPPKLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWP 447
L P+ PP P QP++ P +PP+ +P P A P T P
Sbjct: 606 DDDKL-SKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWP-ATPP 663
Query: 448 PVNEGP---------PKPPTELEPEPEIEGLLTPVLEA-----GDVDEGPVARPLSPTRL 493
GP P P + P I T + + D GP +P P
Sbjct: 664 KATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQ 723
Query: 494 QPALPPEAQSVPELEEVARVLAEIPR-----PLKRRGSMEQAPAVALPPTHKKQYQQ--- 545
+ + P +A+ E R+ + R P K + P + P H+ +
Sbjct: 724 EVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVA 783
Query: 546 IISRLFHRHGGPGPGGPEPELSPITEGSEARAGPPAPAPP 585
++ R G GPG P + E A PPA A P
Sbjct: 784 VVMPTLARGGAAGPGEP----VEVKEPPGLPAKPPASAQP 819
Score = 64.3 bits (155), Expect = 4e-10
Identities = 76/303 (25%), Positives = 99/303 (32%), Gaps = 51/303 (16%)
Query: 352 IPMPPSSPQPRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLPGSPLFTRAPPPKLQPQPQ 411
IP PP P P G P+ P + S A P L PPP + P P
Sbjct: 139 IPPPPPGPAP-GPPQDISEPPG------GSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPP 191
Query: 412 PQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPPVNEGPPKPPTELEPEPEIEGLLT 471
P + S P P T P PAP PP P PP P L
Sbjct: 192 PVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFP 251
Query: 472 P----------VLEAGDVDEGPVARPLSPT---------------------RLQPALPPE 500
P L + + P SP ++ P P
Sbjct: 252 PGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVR 311
Query: 501 AQSVPELEEVARVLAEIPRPLKRRGSMEQAPA-VALPPT-HKKQYQQIISRLFHRHGGPG 558
S+P E E PR K G+ ++AP+ + LPP+ H + Q+ PG
Sbjct: 312 TSSIPVQE-----AQEAPR--KEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPG 364
Query: 559 ----PGGPEPELSPITEGSEARAGPPAPAPPAPIPPPAPSQSSPPEQPQSMEMRSVLRKA 614
P L ++ RAG P PAPP P P P +PP P + + + A
Sbjct: 365 ELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAA 424
Query: 615 GSP 617
P
Sbjct: 425 HPP 427
Score = 63.2 bits (152), Expect = 1e-09
Identities = 154/661 (23%), Positives = 223/661 (33%), Gaps = 120/661 (18%)
Query: 54 PAPPGPQAGPP---SRPPRYSSSSIPEPFGSRGSPRKAATDGADTPFGRSESAPTLHPYS 110
P PPGP GPP S PP S +P P + P + P P L S
Sbjct: 141 PPPPGPAPGPPQDISEPP--GGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALS 198
Query: 111 PLSPKGRPSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRAPSPRPGPGPLRQQG 170
P PS P P ++ P P AF L P P P P P
Sbjct: 199 PPHTLSSPSIPTPPDFIPP-----------APPLAF------LAPPPPPVPAPAP---PA 238
Query: 171 PPTPFDFLGRAGSPRGSPLAEGPQAFFPERGPSPR--PPATAYDAPASAFGSSLLGSGGS 228
P +P R P G + A + + R PP + + SA G +
Sbjct: 239 PASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPN------- 291
Query: 229 AFAPPLRAQDDLTLRRRPPKAWNESDLDV-AYEKKPSQTASYERLDVFARPASPSLQLLP 287
P + + PP S + V ++ P + + P PS + P
Sbjct: 292 ---PEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRP 348
Query: 288 WRESSLDGLGGTGKDNLTSATLPRNYKVSPLASDRRSDAGSYRRSLGSAGPSGTLPRSWQ 347
+ D AT P SP +S A G+ P+ LP
Sbjct: 349 ASQVYPDRAPEPDCPGELKATAP----ASPRLGQSQSQAD---ERAGTPPPAPPLP---P 398
Query: 348 PVSRIPMPPSSPQPRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLPGSPLFTRAP---PP 404
P +P PP+ P P AP P+P A +A P + FT+ P P
Sbjct: 399 PAPPLP-PPAPPLPPAAP---PLPC--------------AQKAAHPPAG-FTKTPKSSSP 439
Query: 405 KLQPQPQPQPQPQ----SQPQPQLPPQPQTQPQTPTPA---PQHPQQTWPPVNEGPPKPP 457
L+P+P P P P+ S P P + + A + + GP P
Sbjct: 440 ALKPKPNP-PSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAP 498
Query: 458 TELEPE-----PEIEGLLTPVLEAGDVDEGPVAR-----PLSPTRLQPALP-PEAQSVPE 506
E + PE E LL+ L A D G + L+ T P+L P +P+
Sbjct: 499 QSKEGKKGPRLPEKETLLS--LPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQ 556
Query: 507 ---LEEVARVLAEIPRPLKRRGSMEQAPAV-ALPPTHKKQYQQI---------ISRLFHR 553
V ++ E+ L E P++ +LPP + + +I +S+ +
Sbjct: 557 DSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAK 616
Query: 554 HGGPGPGGPEPELSPITEGSEARAGPPAPAPPAPIPPPA-------PSQSSPPEQP--QS 604
+ P P S + A PP P IPP A P + P P +
Sbjct: 617 NLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATPLKAT 676
Query: 605 MEMRSVLRKAGSPRKARRARLNP-----LVLLLDAALTGELEVVQQAVKEMNDPSQPNEE 659
+ L+ P A A P L+ D+ G+ E + A +E++ PSQ E
Sbjct: 677 SGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPE--KPASQEVSTPSQARGE 734
Query: 660 G 660
G
Sbjct: 735 G 735
Score = 61.2 bits (147), Expect = 4e-09
Identities = 118/491 (24%), Positives = 165/491 (33%), Gaps = 77/491 (15%)
Query: 127 LQPDAYGSLDRATSPRPRAFDG---------AGSSLGRAPSPRPGPGPLRQQGPPTPFDF 177
L+P YG P P G GS L PS P P PL + PP P
Sbjct: 128 LRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPP--- 184
Query: 178 LGRAGSPRGSPLAEGPQAFFPERGPS-PRPPATAYDAPASAFGSSLLGSGGSAFAPPLRA 236
+ +P P+ E PS P PP AP AF + + P +
Sbjct: 185 ---SMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPAS 241
Query: 237 QDDLTLRRRPPKAWNESDLDVAYEKKPSQTASYERLDVFARPASPSLQLLPWRESSLDGL 296
+ R PP + DVA + ++ + P SP+ E L
Sbjct: 242 PHTVGTRLFPPGGVTKWKSDVALNGRQAEATR------ASPPRSPA-------EPKGSAL 288
Query: 297 GGTGKDNLTSATLPRNYKVSPLASDRRSDAGSYRRSLGSAGPSGTLPRSWQPVSRIPMPP 356
G + +L T PR++KV P R S G ++ SR+P+PP
Sbjct: 289 GPNPEPHL---TFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKA---PSRLPLPP 342
Query: 357 S---SPQPRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLPGSPLFTRAPPPKLQPQPQPQ 413
S P + P + P P G +A P SP Q Q Q
Sbjct: 343 SFHIRPASQVYPDRAPEPDC-----------PGELKATAPASPRL---------GQSQSQ 382
Query: 414 PQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWP-PVNEGPPKPPTELEPEPEIEGLLTP 472
++ P PP P P P PAP P P P + PP P+ +P
Sbjct: 383 ADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSS---SP 439
Query: 473 VLEAGDVDEGPVARPLSPTRLQPALPPEAQSVPELEEVARVLAEI---PRPLKRRGSMEQ 529
L+ P P SP + P + + ++E++ LA R R S
Sbjct: 440 ALK-------PKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRP 492
Query: 530 APAVALPPTHKKQYQQIISR---LFHRHGGPGPGGPEPELSPITEGSEARAGPPAPAPPA 586
P VA K+ ++ + L PG PE L + +E A P P
Sbjct: 493 GPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGG-SSLTETEAAPSLTLPSV 551
Query: 587 P-IPPPAPSQS 596
IP +P+ S
Sbjct: 552 DYIPQDSPTPS 562
Score = 47.8 bits (112), Expect = 4e-05
Identities = 70/236 (29%), Positives = 87/236 (36%), Gaps = 61/236 (25%)
Query: 406 LQPQPQPQPQPQSQPQPQLPPQPQTQPQ--TPTPAPQHPQQTWPPVNEGPPKPPTELEPE 463
L P P P P P PPQ ++P +P P+P PP+ PP PP+ P
Sbjct: 138 LIPPPPPGPAPG-------PPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPP 190
Query: 464 PEIEGLLTPVLEAGDVDEGPVARPLSP--TRLQPALPPEAQSVPELEEVARVLAEIPRPL 521
P PVLEA LSP T P++P +P +A LA P P+
Sbjct: 191 P-------PVLEA-----------LSPPHTLSSPSIPTPPDFIPPAPPLA-FLAPPPPPV 231
Query: 522 KRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPELSPIT----EGSEARA 577
PA A P T + +RLF PGG S + + RA
Sbjct: 232 ----PAPAPPAPASPHT-------VGTRLF------PPGGVTKWKSDVALNGRQAEATRA 274
Query: 578 GPP-APAPP---APIPPPAP------SQSSPPEQPQSMEMRSVLRKAGSPRKARRA 623
PP +PA P A P P P S PP P V +PRK A
Sbjct: 275 SPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGA 330
>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
sapiens]
Length = 309
Score = 77.0 bits (188), Expect = 7e-14
Identities = 82/302 (27%), Positives = 110/302 (36%), Gaps = 66/302 (21%)
Query: 332 SLGSAGPSGTLPRSWQPVSRIPMPPSSPQPR----GAPRQRPIPLSMIFKLQNAFWEHGA 387
S+ S P G P+ R P PP P+ R G Q P P
Sbjct: 30 SVISGKPEGRRPQGGNQPQRTPPPPGKPEGRPPQGGNQSQGPPPR--------------- 74
Query: 388 SRAMLPGSPLFTRAPPPKLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWP 447
PG P PPP+ Q Q P +P+ Q PPQ Q Q P P P P+ P
Sbjct: 75 -----PGKP---EGPPPQGGNQSQGPPPRPGKPEGQ-PPQGGNQSQGPPPRPGKPEGPPP 125
Query: 448 P---VNEGPPKPPTELEPEPEIEGLLT------------PVLEAGDVDEGPVARPLSPTR 492
++GPP P + E P G + P + G+ +GP P P
Sbjct: 126 QGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEG 185
Query: 493 LQPALPPEAQSVPELEEVARVLAEIPRPLKRRGSMEQAPAVAL-PPTHKKQYQQIISRLF 551
P ++Q P PRP K G Q + PP + + S+
Sbjct: 186 PPPQGGNQSQGPP------------PRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGG 233
Query: 552 HRHGGPGPGGPEPELSPITEGSEARAGPP-----APAPPA-----PIPPPAPSQSSPPEQ 601
++ GP P +P+ P EG++ + PP P PP P+PPPA PP
Sbjct: 234 NKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQGPPPP 293
Query: 602 PQ 603
PQ
Sbjct: 294 PQ 295
Score = 65.9 bits (159), Expect = 2e-10
Identities = 80/294 (27%), Positives = 101/294 (34%), Gaps = 46/294 (15%)
Query: 330 RRSLGSAGPSGTLPRSWQPVSRIPM--------PPSSPQPRGAP----RQRPIPLSMIFK 377
RR G P T P +P R P PP +P G P Q P K
Sbjct: 39 RRPQGGNQPQRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGK 98
Query: 378 LQNAFWEHGASRAMLPGSPLFTRAPPPKLQPQPQ-PQPQPQSQPQPQLPPQPQTQPQTPT 436
+ + G P P PPP+ Q Q P P+P P PPQ Q Q P
Sbjct: 99 PEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGP--PPQGGNQSQGPP 156
Query: 437 PAPQHPQQTWPP---VNEGPPKPPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRL 493
P P P+ P ++GPP P + E P + G+ +GP RP P
Sbjct: 157 PRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPP---------QGGNQSQGPPPRPGKPEGP 207
Query: 494 QPALPPEAQSVPELEEVARVLAEIPRPLKRRGSMEQAPAVAL-PPTHKKQYQQIISRLFH 552
P ++Q P PRP K G Q PP H + Q + +
Sbjct: 208 PPQGGNQSQGPP------------PRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGN 255
Query: 553 RHGGPGPGGPEPELSPITEGSEARAGPPAPAPPAPIPPP------APSQSSPPE 600
+ P P G P + PPA P P PPP P Q PP+
Sbjct: 256 KPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQGPPPPPQGGRPHRPPQGQPPQ 309
Score = 60.8 bits (146), Expect = 5e-09
Identities = 63/228 (27%), Positives = 87/228 (38%), Gaps = 59/228 (25%)
Query: 388 SRAMLPGSPLFTRAPPPKLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWP 447
S +++ G P R P+ QPQ P P +P+ + PPQ Q Q P P P P+ P
Sbjct: 28 SPSVISGKPEGRR---PQGGNQPQRTPPPPGKPEGR-PPQGGNQSQGPPPRPGKPEGPPP 83
Query: 448 P---VNEGPPKPPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPALPPEAQSV 504
++GPP P + E +P + G+ +GP RP P P ++Q
Sbjct: 84 QGGNQSQGPPPRPGKPEGQPP---------QGGNQSQGPPPRPGKPEGPPPQGGNQSQGP 134
Query: 505 PELEEVARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPEP 564
P PRP K G PP Q Q GP P +P
Sbjct: 135 P------------PRPGKPEGP---------PPQGGNQSQ-----------GPPPRPGKP 162
Query: 565 ELSPITEGSEARAGPPAPAPP----------APIPPPAPSQ-SSPPEQ 601
E P G++++ PP P P + PPP P + PP Q
Sbjct: 163 EGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQ 210
Score = 58.2 bits (139), Expect = 3e-08
Identities = 48/166 (28%), Positives = 59/166 (35%), Gaps = 26/166 (15%)
Query: 53 SPAPPGPQAGPPSRPPRYSSSSIPEPFGSRGSPRKAATDGADTP--FGRSESAPTLHPYS 110
+P PPG G P + S P P G P + P G+ E P
Sbjct: 50 TPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQ 109
Query: 111 PLSPKGRPSSPRTPLYLQPDAYGSLDRATSPRPRAFDG---AGSSLGRAPSPRPG----- 162
P RP P P P G+ + PRP +G G + + P PRPG
Sbjct: 110 SQGPPPRPGKPEGP----PPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGP 165
Query: 163 --PGPLRQQGPPTPFDFLGRAGSPRGSPLAEGPQAFFPERGPSPRP 206
G + QGPP G P G P PQ +GP PRP
Sbjct: 166 PPQGGNQSQGPPP------HPGKPEGPP----PQGGNQSQGPPPRP 201
Score = 52.8 bits (125), Expect = 1e-06
Identities = 77/314 (24%), Positives = 101/314 (32%), Gaps = 42/314 (13%)
Query: 154 GRAPSPRPGPGPLRQQGPPTPFDFLGRAGSPRGSPLAEGPQAFFPERGPSPRPPATAYDA 213
G+ RP G Q+ PP P G P PQ +GP PRP
Sbjct: 34 GKPEGRRPQGGNQPQRTPPPP-----------GKPEGRPPQGGNQSQGPPPRPGKPEGPP 82
Query: 214 PASAFGSSLLGSGGSAFAPPLRAQDDLTLRRRPPKAWNESDLDVAYEKKPSQTASYERLD 273
P G + PP R +PP+ N+S KP
Sbjct: 83 PQ---------GGNQSQGPPPRPGKP---EGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQ 130
Query: 274 VFARPASPSLQLLPWRESSLDGLGGTGKDNLTSATLPR--NYKVSPLASDRRSDAGSYRR 331
P P P + G + P+ N P + + +
Sbjct: 131 SQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQG 190
Query: 332 SLGSAGPSGTLPRSWQPVSRIPMPPSSPQPRGAPRQRPIPLSMIFKLQNAFWEHGASRAM 391
S GP PR +P P P Q +G P RP K + + G
Sbjct: 191 GNQSQGPP---PRPGKPEG--PPPQGGNQSQGPP-PRP------GKPEGPPSQGGNKPQG 238
Query: 392 LPGSPLFTRAPPPKLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPPVNE 451
P P + PPP+ +PQ P P +PQ PP P PQ P P P Q PP +
Sbjct: 239 PPPHPGKPQGPPPQEGNKPQRPPPP---GRPQGPPPPGGNPQQPLPPPAGKPQGPPPPPQ 295
Query: 452 G--PPKPPTELEPE 463
G P +PP P+
Sbjct: 296 GGRPHRPPQGQPPQ 309
Score = 50.4 bits (119), Expect = 7e-06
Identities = 49/163 (30%), Positives = 56/163 (34%), Gaps = 33/163 (20%)
Query: 51 SDSPAP-PGPQAGPPSRPPRYSSSSIPEPFGSRGSPRKAATDGADTPFGRSESAPTLHPY 109
S P P PG GPP + S P P G P P G ++S
Sbjct: 173 SQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPP----------PQGGNQSQ------ 216
Query: 110 SPLSPKGRPSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRAPSPRPGPGPLRQQ 169
P RP P P P G+ + P P G G P P PG R Q
Sbjct: 217 ---GPPPRPGKPEGP----PSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPG--RPQ 267
Query: 170 GPPTP-----FDFLGRAGSPRGSPLAEGPQAFFPERGPSPRPP 207
GPP P AG P+G P PQ P R P +PP
Sbjct: 268 GPPPPGGNPQQPLPPPAGKPQGPP--PPPQGGRPHRPPQGQPP 308
Score = 36.2 bits (82), Expect = 0.13
Identities = 19/52 (36%), Positives = 26/52 (50%), Gaps = 1/52 (1%)
Query: 556 GPGPGGPEPELSPITEGSEARAGPPAPAPPAPIPPPAPSQS-SPPEQPQSME 606
GP P +PE P G++++ PP P P PP +QS PP +P E
Sbjct: 91 GPPPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPE 142
>gi|14195601 protein phosphatase 1, regulatory (inhibitor) subunit
12B isoform b [Homo sapiens]
Length = 998
Score = 76.3 bits (186), Expect = 1e-13
Identities = 42/112 (37%), Positives = 59/112 (52%), Gaps = 4/112 (3%)
Query: 608 RSVLRKAGSPRKARRARLNPLVLLLDAALTGELEVVQQAVKEMNDPSQPNEEGITALHNA 667
R L + GSPR R + L A +G+ + V++ + D + N +G+TALH A
Sbjct: 43 RQPLTRRGSPR----VRFEDGAVFLAACSSGDTDEVRKLLARGADINTVNVDGLTALHQA 98
Query: 668 ICGANYSIVDFLITAGANVNSPDSHGWTPLHCAASCNDTVICMALVQHGAAI 719
N +V FL+ ANVN D+ GWTPLH AASC I + HGA++
Sbjct: 99 CIDENLDMVKFLVENRANVNQQDNEGWTPLHAAASCGYLNIAEYFINHGASV 150
Score = 43.1 bits (100), Expect = 0.001
Identities = 27/78 (34%), Positives = 35/78 (44%), Gaps = 11/78 (14%)
Query: 637 TGELEVVQQAVKEMNDPSQPNEEGITALHNAICGANYSIVDFLITAGANVNSPDSHGWTP 696
+G++E V+QA G TALH A ++ LI AG +N D GWTP
Sbjct: 205 SGKIEDVRQA-----------RSGATALHVAAAKGYSEVLRLLIQAGYELNVQDYDGWTP 253
Query: 697 LHCAASCNDTVICMALVQ 714
LH AA C L +
Sbjct: 254 LHAAAHWGVKEACSILAE 271
Score = 35.0 bits (79), Expect = 0.29
Identities = 24/91 (26%), Positives = 42/91 (46%), Gaps = 3/91 (3%)
Query: 606 EMRSVLRKAGSPRKARRARLNPLVLLLDAALTGELEVVQQAVKEMNDPSQPNEEGITALH 665
E+R +L + ++ L L A + L++V+ V+ + +Q + EG T LH
Sbjct: 73 EVRKLLARGAD---INTVNVDGLTALHQACIDENLDMVKFLVENRANVNQQDNEGWTPLH 129
Query: 666 NAICGANYSIVDFLITAGANVNSPDSHGWTP 696
A +I ++ I GA+V +S G P
Sbjct: 130 AAASCGYLNIAEYFINHGASVGIVNSEGEVP 160
>gi|4505319 protein phosphatase 1, regulatory (inhibitor) subunit
12B isoform a [Homo sapiens]
Length = 982
Score = 76.3 bits (186), Expect = 1e-13
Identities = 42/112 (37%), Positives = 59/112 (52%), Gaps = 4/112 (3%)
Query: 608 RSVLRKAGSPRKARRARLNPLVLLLDAALTGELEVVQQAVKEMNDPSQPNEEGITALHNA 667
R L + GSPR R + L A +G+ + V++ + D + N +G+TALH A
Sbjct: 43 RQPLTRRGSPR----VRFEDGAVFLAACSSGDTDEVRKLLARGADINTVNVDGLTALHQA 98
Query: 668 ICGANYSIVDFLITAGANVNSPDSHGWTPLHCAASCNDTVICMALVQHGAAI 719
N +V FL+ ANVN D+ GWTPLH AASC I + HGA++
Sbjct: 99 CIDENLDMVKFLVENRANVNQQDNEGWTPLHAAASCGYLNIAEYFINHGASV 150
Score = 43.1 bits (100), Expect = 0.001
Identities = 27/78 (34%), Positives = 35/78 (44%), Gaps = 11/78 (14%)
Query: 637 TGELEVVQQAVKEMNDPSQPNEEGITALHNAICGANYSIVDFLITAGANVNSPDSHGWTP 696
+G++E V+QA G TALH A ++ LI AG +N D GWTP
Sbjct: 205 SGKIEDVRQA-----------RSGATALHVAAAKGYSEVLRLLIQAGYELNVQDYDGWTP 253
Query: 697 LHCAASCNDTVICMALVQ 714
LH AA C L +
Sbjct: 254 LHAAAHWGVKEACSILAE 271
Score = 35.0 bits (79), Expect = 0.29
Identities = 24/91 (26%), Positives = 42/91 (46%), Gaps = 3/91 (3%)
Query: 606 EMRSVLRKAGSPRKARRARLNPLVLLLDAALTGELEVVQQAVKEMNDPSQPNEEGITALH 665
E+R +L + ++ L L A + L++V+ V+ + +Q + EG T LH
Sbjct: 73 EVRKLLARGAD---INTVNVDGLTALHQACIDENLDMVKFLVENRANVNQQDNEGWTPLH 129
Query: 666 NAICGANYSIVDFLITAGANVNSPDSHGWTP 696
A +I ++ I GA+V +S G P
Sbjct: 130 AAASCGYLNIAEYFINHGASVGIVNSEGEVP 160
>gi|14149716 protein phosphatase 1, regulatory subunit 12C [Homo
sapiens]
Length = 782
Score = 74.7 bits (182), Expect = 3e-13
Identities = 55/165 (33%), Positives = 73/165 (44%), Gaps = 21/165 (12%)
Query: 580 PAPAPPAPIPPPAPSQSSPPEQPQSMEMRSVLRKAGSPRKARRARLNPLVLLLDAALTGE 639
PA P A A ++ EQ + R+ R+AR R L A G+
Sbjct: 7 PAAGPGAAA---AAARERRREQLRQWGARAGAEPGPGERRARTVRFERAAEFLAACAGGD 63
Query: 640 LEVVQQAVKEMN-------DPSQP----------NEEGITALHNAICGANYSIVDFLITA 682
L+ + ++ + DP+ P N +GI+ALH A N +V FL+
Sbjct: 64 LDEARLMLRAADPGPGAELDPAAPPPARAVLDSTNADGISALHQACIDENLEVVRFLVEQ 123
Query: 683 GANVNSPDSHGWTPLHCAASCNDTVICMALVQHGAAIFATTLSDG 727
GA VN D+ GWTPLH AASC I L+ HGA I A SDG
Sbjct: 124 GATVNQADNEGWTPLHVAASCGYLDIARYLLSHGANIAAVN-SDG 167
Score = 43.1 bits (100), Expect = 0.001
Identities = 22/64 (34%), Positives = 30/64 (46%)
Query: 660 GITALHNAICGANYSIVDFLITAGANVNSPDSHGWTPLHCAASCNDTVICMALVQHGAAI 719
G +ALH A ++ L+ AG + D GWTPLH AA C L +HG +
Sbjct: 227 GASALHVAAAKGYIEVMRLLLQAGYDPELRDGDGWTPLHAAAHWGVEDACRLLAEHGGGM 286
Query: 720 FATT 723
+ T
Sbjct: 287 DSLT 290
Score = 39.7 bits (91), Expect = 0.012
Identities = 36/121 (29%), Positives = 53/121 (43%), Gaps = 20/121 (16%)
Query: 582 PAPPAPIPPPAPSQSSPPEQPQSMEMRSVLRKAGSPRKARRARLNPLVLLLDAALTGELE 641
P P A + P AP PP R+VL + + + L A + LE
Sbjct: 76 PGPGAELDPAAP----PPA-------RAVLDSTNA---------DGISALHQACIDENLE 115
Query: 642 VVQQAVKEMNDPSQPNEEGITALHNAICGANYSIVDFLITAGANVNSPDSHGWTPLHCAA 701
VV+ V++ +Q + EG T LH A I +L++ GAN+ + +S G PL A
Sbjct: 116 VVRFLVEQGATVNQADNEGWTPLHVAASCGYLDIARYLLSHGANIAAVNSDGDLPLDLAE 175
Query: 702 S 702
S
Sbjct: 176 S 176
Score = 33.5 bits (75), Expect = 0.83
Identities = 43/177 (24%), Positives = 65/177 (36%), Gaps = 43/177 (24%)
Query: 472 PVLEAGDVDEGPVARPLSPTRLQPALP----PEAQSVPELEEVARVLAEIPRPLKRR-GS 526
P+ + + +EGP P + R + P +S +LEE P RR G
Sbjct: 372 PIQDEDEGEEGPTEPPPAEPRTLNGVSSPPHPSPKSPVQLEEA---------PFSRRFGL 422
Query: 527 MEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPELSPITEGSEARAGP------- 579
++ + AL P ++ + G PG G S EG+ +A
Sbjct: 423 LKTGSSGALGPPERRTAE----------GAPGAGLQRSASSSWLEGTSTQAKELRLARIT 472
Query: 580 PAPAPPAPIP---------PPAPSQSSPPE---QPQSMEMRSVLRKAGSPRKARRAR 624
P P+P P P PP SSPP +P+S +V + +P R R
Sbjct: 473 PTPSPKLPEPSVLSEVTKPPPCLENSSPPSRIPEPESPAKPNVPTASTAPPADSRDR 529
>gi|188536004 zinc finger protein 469 [Homo sapiens]
Length = 3925
Score = 73.9 bits (180), Expect = 6e-13
Identities = 146/580 (25%), Positives = 210/580 (36%), Gaps = 99/580 (17%)
Query: 56 PPGPQAGPPSRP--PRYSSSSIPEPFGSRGSPRKAATDGADTPFGRSESAPTLHPYSPLS 113
P GP G P RP PR + E G ++ + T + + P P +P
Sbjct: 153 PQGPGTGAPLRPGLPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATP--RPPAPGP 210
Query: 114 PKGRPSSPRTPLYLQPDAYGSLDRATSPR-PRAFDGA--GSSLGRAPS-PRPGPGPLRQQ 169
P+ R +SP LQP +Y + + P A + + G++ G P+ P P P R
Sbjct: 211 PQSRGTSP-----LQPGSYPEYQASGADSWPPAAENSFPGANFGVPPAEPEPIPKGSRPG 265
Query: 170 GPPT------PFDFLGRAGSPRGSPLAEGPQAFFPERGPSPRPPATAYDAPASAFGSSLL 223
G P PF L A S + P AF + P A+ P A+ +
Sbjct: 266 GSPRGVSFQFPFPALHGA-STKPFPADVAGHAF------TNGPLVFAFHQPQGAWPEEAV 318
Query: 224 GSGGSAFAPPLRAQDDLTLRRRPPKAWNE-SDLDVAYEKKPSQTASYERLDVFARPASPS 282
G+G + P A L + P N SDL A + ++ RP S S
Sbjct: 319 GTGPAYPLPTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSA-------PRPFSDS 371
Query: 283 L-----QLLPWRE-SSLDGLGGTGKDNLTSATLPRNYKVSPL--ASDRRSDAGSYRRSLG 334
L ++LP R S+ DGLG T ++LP+ + AS + G L
Sbjct: 372 LHKSLTKILPERPPSAQDGLGSTRGP---PSSLPQRHFPGQAYRASGVDTSPGPPDTELA 428
Query: 335 SAGPS-GTLPRSWQPVSRIPMPPSSPQPRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLP 393
+ GP LP+ W P + P P P A R SM F Q + P
Sbjct: 429 APGPPPARLPQLWDPTAA-PYPTPPGGPLAATR------SMFFNGQPS-----------P 470
Query: 394 GSPLFTRAPPPKLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPPVNEGP 453
G L P+ P P PQ P ++P P P P P+ W ++G
Sbjct: 471 GQRLCL----PQSAPLPWPQVLPTARPSPHGMEMLSRLP-FPAGGPE-----WQGGSQGA 520
Query: 454 ----PKPPTELEPEPEIEGLL--TPVLEAGDVDEGPVARPLSPTRLQPALPPEAQ-SVPE 506
K P E P + +P L + P A+PL QP + P S+P
Sbjct: 521 LGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPP 580
Query: 507 LEEVARVLAEIPRPLKRRGSMEQ-----APAVALPPTHKKQYQQIISRLFHRHGGPGPGG 561
V +E P P + +P + P + Q+ PGP G
Sbjct: 581 PRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQL----------PGPLG 630
Query: 562 PEPELSPITEGSEARAGPPAPAPPAPIP---PPAPSQSSP 598
P P T E + P+P PP +P P P+++ P
Sbjct: 631 PSAFFHPPTHPQETGSPFPSPEPPHSLPTHYQPEPAKAFP 670
Score = 47.8 bits (112), Expect = 4e-05
Identities = 157/670 (23%), Positives = 224/670 (33%), Gaps = 147/670 (21%)
Query: 53 SPAPPGPQAGPPSRPPR-----YSSSSIPEPF---GSRGSPRKAATDGADTPFGR---SE 101
SP PP + P PP + ++ P P G + R +G +P R +
Sbjct: 419 SPGPPDTELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQ 478
Query: 102 SAPTLHPYSPLSPKGRPSSPRTPLYLQPDAYGSLDRATSPR-----PRAFDGAGSSLGRA 156
SAP P+ + P RPS P L R P GA + G+
Sbjct: 479 SAPL--PWPQVLPTARPS---------PHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKT 527
Query: 157 PSPRPGPGPLR--QQGPPTPFDFLGRAG---------------SPRGSPLAEGPQAF--F 197
P PR +R Q G P F + G SP G+P P+
Sbjct: 528 PGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGAS 587
Query: 198 PERGPSPRP-------------PATAYDAPASAFGSSLLGSGGSA--FAPPLRAQDDLTL 242
P P P P P ++ A S+ S L G G + F PP Q+ +
Sbjct: 588 PSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSP 647
Query: 243 RRRPPKAWNESDLDVAYEKKPSQTASYERLDVFARPASPSLQLLPW-RESSLDGLGG--- 298
P + L Y+ +P++ + + A A L+ P+ E G GG
Sbjct: 648 FPSPEPPHS---LPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEVGRGGLQG 704
Query: 299 ---------TGKDNLTSATLPRNYKVSPLASDRRSDAG--------SYRRSLGSAGPSGT 341
T +L+SA+L + + L + R+ D ++R+ G
Sbjct: 705 FPRAPPPYPTHHFSLSSASLDQ---LDVLLTCRQCDRNYSSLAAFLAHRQFCGLL----- 756
Query: 342 LPRSWQPVSRIPMPPSSPQPRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLPGSPLFTR- 400
L R+ R P PP P P APR + + F G ++A PL T
Sbjct: 757 LARAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGKDDPLRTGF 816
Query: 401 APPPKLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPPVNEGPPKPPTEL 460
P P P P + +L T A +
Sbjct: 817 LPSLAATPFPLPASDLDMEDDAKL-------DSLITEALNGMEYQ--------------- 854
Query: 461 EPEPEIEGLLTPVLEAGDVDEGPVARPLS--PTRLQPALPPEAQSVPELEEVARVLAEIP 518
PEI+ V A + GP P S P + + + PE+++ P L A + P
Sbjct: 855 SDNPEIDSSFIDVF-ADEEPSGP-RGPSSGHPLKSKAGVTPESKAPPPL-PAATPDPQTP 911
Query: 519 RPLKR----RG-----SMEQAPAVALPPTHKKQYQQIIS-RLFHRH---------GGPGP 559
RP R RG S+ AP A P+ +Q ++ +LF + G G
Sbjct: 912 RPGDRGCPARGRPKTRSLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGG 971
Query: 560 GGPEPELSPITEGSEARAGPPAPAPPAPIPP-----PAPSQSSPPEQPQSMEMRSVLRKA 614
GG L P PP P P P PAP P+ E RS R+
Sbjct: 972 GGRASGLRPRRNDGLGERPPPRPRRPRTQAPGSRADPAPRVPRAAALPE--ETRSSRRRR 1029
Query: 615 GSPRKARRAR 624
PRK R R
Sbjct: 1030 LPPRKDPRKR 1039
Score = 46.6 bits (109), Expect = 9e-05
Identities = 100/408 (24%), Positives = 133/408 (32%), Gaps = 56/408 (13%)
Query: 45 QLESLWSDSPAPPGPQAGPPSRPPRYSSSSIPEPFGSRGS-PRKAATDGADTPFGRSESA 103
Q + W + GP P++P + S +P G G R + GA + G + SA
Sbjct: 308 QPQGAWPEEAVGTGPAYPLPTQP---APSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSA 364
Query: 104 PTLHPYSPLSPKGRPSS-PRTPLYLQPDAYGSLDRATSPRP-RAFDG-AGSSLGRAPSPR 160
P P+S K P P Q D GS S P R F G A + G SP
Sbjct: 365 P--RPFSDSLHKSLTKILPERPPSAQ-DGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPG 421
Query: 161 PGPGPLRQQGPPTPFDFLGRAGSPRGSPLAEGPQAFFPERGPSPRPPATAYDAPASAFGS 220
P L GPP A PQ + P P P PP A S F +
Sbjct: 422 PPDTELAAPGPPP----------------ARLPQLWDPTAAPYPTPPGGPLAATRSMFFN 465
Query: 221 SLLGSGGSAFAPPLRAQDDLTLRRRPPKAWNESDLDVAYEKKPSQTASYERLDVFARPAS 280
G L L + P W + V +PS E L PA
Sbjct: 466 GQPSPG-----------QRLCLPQSAPLPWPQ----VLPTARPSPHGM-EMLSRLPFPAG 509
Query: 281 PSLQLLPWRESSLDGLGGTGK-----DNLTSATLPRNYKVSPLASDRRSDAGSYRRSLGS 335
W+ S LG GK + L + + + + +D G+ G
Sbjct: 510 GP----EWQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGV 565
Query: 336 A----GPSGTLPRSWQPVSRIPMPPSSPQPRGAPRQRPIPLSMIFKLQNAFWEHGASRAM 391
A P GT P P P SP P A S + + ++ + +
Sbjct: 566 AQPQVSPHGT-PSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQ 624
Query: 392 LPGSPLFTRAPPPKLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAP 439
LPG + P PQ P P +P LP Q +P P P
Sbjct: 625 LPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFP 672
Score = 45.4 bits (106), Expect = 2e-04
Identities = 127/600 (21%), Positives = 180/600 (30%), Gaps = 129/600 (21%)
Query: 48 SLWSDSPAPPGPQAGPPSRPPRYSSSSIPEPFGSR--GSPRKAATDGADTPFGRSESAPT 105
SL +P+ + G P PP S P R GSP + G S + PT
Sbjct: 77 SLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYILG----IASSRTKPT 132
Query: 106 LH--PYSPL----------SPKG-------RPSSPRTPLYLQPDAYGSLDRATSPRPRAF 146
L P +P +P+G RP PRT + G R P +F
Sbjct: 133 LDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAEELG-FHRCFQEPPSSF 191
Query: 147 DGAGSSLGRAPSPRPGPGPLRQQGPPTPFDFLGRAGSPRGSPLAEGPQAFFPERGPSPRP 206
+ A P PGP + +G SPL G + G P
Sbjct: 192 TSTNYTSPSATPRPPAPGPPQSRGT---------------SPLQPGSYPEYQASGADSWP 236
Query: 207 PATAYDAPASAFGSSLLGSGGSAFAPPLRAQDDLTLRRRPPKAWNESDLDVAYEKKPSQT 266
PA P + FG PP + + RP S V+++
Sbjct: 237 PAAENSFPGANFG-----------VPPAEPEP-IPKGSRP----GGSPRGVSFQ------ 274
Query: 267 ASYERLDVFARPASPSLQLLPWRESSLDGLGGTGKDNLTSATLPRNYKVSPLASDRRSDA 326
F PA L G + + PL
Sbjct: 275 --------FPFPA----------------LHGASTKPFPADVAGHAFTNGPLVFAFHQPQ 310
Query: 327 GSYRRSLGSAGPSGTLPRSWQPVSRIPMPPSSPQPRGAPRQ-----------------RP 369
G++ GP+ LP P P+P QP G R RP
Sbjct: 311 GAWPEEAVGTGPAYPLPTQPAPS---PLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRP 367
Query: 370 IPLSMIFKLQNAFWEHGASRAMLPGSPLFTRAPPPKLQPQPQPQPQPQSQPQPQLPPQPQ 429
S+ L E S GS TR PP L + P ++ P P
Sbjct: 368 FSDSLHKSLTKILPERPPSAQDGLGS---TRGPPSSLPQRHFPGQAYRASGVDTSPGPPD 424
Query: 430 TQPQTPTPAPQHPQQTWPPVNEGPPKPPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLS 489
T+ P P P Q W P P P P + + + P S
Sbjct: 425 TELAAPGPPPARLPQLWDPTAAPYPTP-----PGGPLAATRSMFFNGQPSPGQRLCLPQS 479
Query: 490 PTRLQPALPPEAQSVPE-LEEVARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIIS 548
P + P A+ P +E ++R+ P + GS P +++ + S
Sbjct: 480 APLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKLPAVRS 539
Query: 549 ------RLFHRHGGPGPGGPEPELSPITEGSEARAGPPAPAPPAPIPPPAPSQSSPPEQP 602
LF +G PG +P + + + G P+ +PPP +SP E P
Sbjct: 540 SQGGSPALFTYNGMTDPGA-QPLFFGVAQPQVSPHGTPS------LPPPRVVGASPSESP 592
Score = 38.9 bits (89), Expect = 0.020
Identities = 58/232 (25%), Positives = 71/232 (30%), Gaps = 45/232 (19%)
Query: 401 APPPKLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPPVNEGPPKPPT-- 458
APPP + QP+ S P PP P T T E P P
Sbjct: 9 APPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAMELPEAQPRQA 68
Query: 459 ---ELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPALPPEAQSVPELEEVARVLA 515
EL+P P + G P G SP + L A+ P + + +
Sbjct: 69 RDGELKP-PSLRG-QAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYILGIAS 126
Query: 516 EIPRP-LKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPELSPITEGSE 574
+P L Q A LP Q GPG G P P TE
Sbjct: 127 SRTKPTLDETPENPQLEAAQLPEVDTPQ-------------GPGTGAPLRPGLPRTEAQP 173
Query: 575 AR---------AGPPA-------------PAPPAPIPPPAPSQSSPPEQPQS 604
A PP+ P PPAP PP S+ + P QP S
Sbjct: 174 AAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPP--QSRGTSPLQPGS 223
Score = 35.4 bits (80), Expect = 0.22
Identities = 114/496 (22%), Positives = 170/496 (34%), Gaps = 66/496 (13%)
Query: 128 QPDAYGSLDRATSP--RPRAFDGA-GSSLGRAPSPRPGPGPLRQQGPPTPFDFLGRAGSP 184
QP A+ + R +P + RA +G S R P PGP + PP + GS
Sbjct: 3418 QPFAFRGVRRPGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSL 3477
Query: 185 RG-----SPLAEGPQAFFPERGPSPRPPATAYDAPASAFGSSLLGSGGSAFAPPLRAQDD 239
S +A +PE P P T L S PP +
Sbjct: 3478 PALLHLCSEVAPSTTKGWPETLERPVDPVT------HPIRGCELPSNHQECPPPSLSPFP 3531
Query: 240 LTLRRRPPKAWNESDLDVAYEKKPSQTA--SYERLDVFARPASPSLQLLPWRESSLDG-- 295
L + LD A E+ ++ + S L A P SL R +G
Sbjct: 3532 AALA----DGRGDCALDGALERPENEASPGSPGPLLQQALPLGASLPRPGARGQDAEGKR 3587
Query: 296 --LGGTGKDNLTSAT---LPRNYKVSPLASDRRSDAGSYRRSLGSAGPSGTL-------P 343
L +GK A P +++ L + + S+ S G GP GT P
Sbjct: 3588 APLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEG--GPRGTFHKGSATKP 3645
Query: 344 RSWQPVSRIPMPPSSPQPRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLPGSPLFTRAPP 403
Q S+ S+P A + P + L G M P +P P
Sbjct: 3646 AGCQSSSKDRSAASTPSK--ALKFPVHPRKAVGSLAPGELARGTENGMKPATP--KAKPG 3701
Query: 404 PKLQPQPQPQPQPQ----SQPQP---QLPPQPQTQPQTP-----TPAPQH-PQQTWPPVN 450
P Q P+P + SQPQP QL + T P P +PAP+ P +
Sbjct: 3702 PSSQGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSC 3761
Query: 451 EGPPKPPTELEPE----PEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPALPPEAQSVPE 506
P+ E P P+ +G + + G V + + P+ P + P
Sbjct: 3762 TKGPREAGEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPPRTPR 3821
Query: 507 LEEV-ARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPE 565
+ +RVL P+P + + P PP+ +++ + ++ R G P G P
Sbjct: 3822 KQATPSRVLPTKPKP-----NSQNKPRP--PPSEQRKAEPGHTQRKDRLGKAFPQG-RPL 3873
Query: 566 LSPITEGSEARAGPPA 581
L P G+ PA
Sbjct: 3874 LRPPKRGTAVHGAEPA 3889
Score = 35.0 bits (79), Expect = 0.29
Identities = 151/643 (23%), Positives = 207/643 (32%), Gaps = 141/643 (21%)
Query: 55 APPGPQAGPPSRPP-RYSSSSIPEPFGSRG-SPRKAATDGADTPFGRS--ESAPTLHPYS 110
A P P P+R + ++ GS G +P +A++ G + P + AP++ +
Sbjct: 2024 AEPTPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAPSVGDLA 2083
Query: 111 PLSPKGRPSSPRTPLYLQPDAYGSLDRA---TSPRPRAFDGAGSSLGRAPSPRPGPGPLR 167
+P SP + ++ P + G L R TSP RA G G L +PS R PGP +
Sbjct: 2084 ACAP-----SPTSAAHM-PCSLGPLPREDPLTSPS-RAQGGLGGQLPASPSCRDPPGPQQ 2136
Query: 168 QQGPPTPFDFLGRAGSPRGSPL--AEGPQAFF---PERGPSPRPPATAYDA-PASAFGSS 221
A SP +PL A+G QA E P P T P A
Sbjct: 2137 L-----------LACSPAWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDPKEALAGC 2185
Query: 222 LLGSGGSAFAPPLR----------------AQDDLTLR----RRPPKAWNESDLDVAYEK 261
LL GS P D TLR R K W +
Sbjct: 2186 LLQGEGSPLEDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLW----------E 2235
Query: 262 KPSQTASYERLDVFARPASPS-------LQLLPWRESSLDGLGGTGKDNLTSATLPRNYK 314
P + S A SPS L P + + G G G D P++
Sbjct: 2236 SPGRATS----PPLAGAVSPSVAVRATGLSSTPTGDEAQAGRGLPGPD-------PQSRG 2284
Query: 315 VSPLASDRRSDAGSYRRSLGSAGPSGTL---PRSWQPVSRIPMPPSSPQPRGAPRQRPIP 371
P + R G S PS T R Q V+ +P P P +GA P
Sbjct: 2285 APPHTNPDRMPRGH-----SSYSPSNTARLGHREGQAVTAVPTEP--PTLQGAGPDSPAC 2337
Query: 372 LSMIFKLQNAFWEHGAS--RAMLPGSPLFTRAPPPKLQPQPQPQ--------PQPQSQPQ 421
L E G S PG+P R+ K+ P P S
Sbjct: 2338 LE---------GEMGTSSKEPEDPGTPETGRSGATKMPRVTCPSTGLGLGRTTAPSSTAS 2388
Query: 422 PQLPPQPQT----QPQTPTPAPQHPQQTWPPVNEGPPKPPTELE----PEPEIEGLLTPV 473
PQ+ QTP P PQ + G K P E G +T
Sbjct: 2389 DFQSDSPQSHRNASHQTPQGDPLGPQDL-KQRSRGYKKKPASTENGQWKGQAPHGPVTCE 2447
Query: 474 LEAGDVDEGPVARPLSPTRLQPALPPEAQSVPELEEVARVLAEIPRPLKRRGSMEQAPAV 533
+ A GP + +P P A + P P L + +E
Sbjct: 2448 VCAASFRSGPGLSRHKARKHRP--HPGAPAEPS-----------PAALPAQQPLEPLAQK 2494
Query: 534 ALPPTHKKQYQQIISRLFHRHGGPGPGGPEPELSPITEGSEARAGPPAPAPPAPIPPPAP 593
PP K R H G P P +GS+ P + PP+P
Sbjct: 2495 CQPPRKKSHRVSGKERPNHSRGDPS----HVTQPPPAQGSKEVLRAPGSPHSQQLHPPSP 2550
Query: 594 SQ-----SSPPEQPQSMEMR--SVLRKAGSPRKARRARLNPLV 629
++ +P +P+ + R + K R+ RR R P V
Sbjct: 2551 TEHEVDVKTPASKPRPDQAREDELHPKQAEKREGRRWRREPTV 2593
Score = 32.0 bits (71), Expect = 2.4
Identities = 47/173 (27%), Positives = 61/173 (35%), Gaps = 35/173 (20%)
Query: 42 LTKQLESLWSDSPAPPGPQA----GPPSRPPRYSSSSIPEPFGSRGS--------PRKAA 89
L K+ E S + GP+ G ++P SSS S S PRKA
Sbjct: 3616 LQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAV 3675
Query: 90 TDGADTPFGRSESAPTLHPYSPLSPKGRPSSPRTPLYLQPDAYGSLDRATSPRPRAFDGA 149
A R T + P +PK +P P + GS SPRP G
Sbjct: 3676 GSLAPGELARG----TENGMKPATPKAKPG---------PSSQGS----GSPRPGTKTGG 3718
Query: 150 GSSLGRAPSPRPGPGPLRQQGPPTPFDFLGRAGSPRGSPLAEGPQAFFPERGP 202
GS P+P G L+ + TP + SP L QA +GP
Sbjct: 3719 GSQ------PQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGP 3765
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 73.9 bits (180), Expect = 6e-13
Identities = 120/479 (25%), Positives = 168/479 (35%), Gaps = 94/479 (19%)
Query: 156 APSPRPGPGPLRQQGPPTPFDFLGRAGSPRGSPLAEGPQAFFPERGPSPRPPATAYDAPA 215
AP P P TP + + P A PQA P + +P+P +P
Sbjct: 616 APVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPE 675
Query: 216 SAFGSSLLGSGGSAFAPPLRAQDDLTLRRRPPKAWNESDLDVAYEKKPSQTASYERLDVF 275
+LG SA + QD L + P+ ++ L + P + +
Sbjct: 676 KI----VLGQPPSATPTAILTQDSLQMFL--PQERSQQPLSA---EGPHLSVPASVIVSA 726
Query: 276 ARPASPSLQLLPWRESSLDGLGGTGKDNLTS-ATLPRNYKVSPLASDRRSDAGS--YRRS 332
PA P + + GLG D+ S A P+ +PL S + S ++
Sbjct: 727 PPPAQDPAPATPVAKGA--GLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAP 784
Query: 333 LGSA----GPSGTLPRSWQP-----VSRIPM-PPSSPQPRGAPRQRPIPLSMIFKLQNAF 382
LG + P T P S P VSR P PP P P P Q P L IF +QN
Sbjct: 785 LGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCP---PPQAPPTLPGIFVIQN-- 839
Query: 383 WEHGASRAMLPGSPLFTRAPPPKLQPQPQPQPQPQSQPQPQLPP---------QPQTQPQ 433
+ G +P P P L+PQ QP P+ P P LPP +T +
Sbjct: 840 -QLGVPPPASNPAPTAPGPPQPPLRPQSQP-PEGPLPPAPHLPPSSTSSAVASSSETSSR 897
Query: 434 TPTPAPQHPQQTWPPVNEGPPKPPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRL 493
P P P Q +PP ++GP K PT P P + L P
Sbjct: 898 LPAPTPSDFQLQFPP-SQGPHKSPT---PPPTLH--LVP--------------------- 930
Query: 494 QPALPPEAQSVPELEEVARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISR-LFH 552
+PA PP P P + PA+ P +++ Q+ S +
Sbjct: 931 EPAAPPP-----------------PPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQ 973
Query: 553 RHGGPGPGGPE--PELSPITE-------GSEARAGPPAPAPPAPIPPPAPSQSSPPEQP 602
G P P+ L P+T +A +G P AP P P + PP P
Sbjct: 974 NKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLP 1032
Score = 67.8 bits (164), Expect = 4e-11
Identities = 146/587 (24%), Positives = 192/587 (32%), Gaps = 143/587 (24%)
Query: 79 FGSRGSPRKAATDGADTPFGRSESAPTLHPYSPLSPKGRPSSPRTPLYLQPDAYGSLD-R 137
FG G AA+ TP G+ + SPL P RTP +QP G L +
Sbjct: 307 FGGAG----AASAPTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPK 362
Query: 138 ATSPRPRAFDGAGSSLGRAPSPRPGPGPLRQQGPPTP----FDFLGRAGSP---RGSPLA 190
P+ F AG++L + + PG L QQ P P F G+AG G P
Sbjct: 363 LYQLTPKPFAPAGATL----TIQGEPGALPQQ-PKAPQNLTFMAAGKAGQNVVLSGFPAP 417
Query: 191 EGPQAFFPE-----RGPSPRPPATAYDAPASAFGSSLLGSGGSAFAPPLRAQDDLTLRRR 245
F + G +P P A P S LL G S P
Sbjct: 418 ALQANVFKQPPATTTGAAPPQPPGALSKPMSVH---LLNQGSSIVIP------------- 461
Query: 246 PPKAWNESDLDVAYEKKPSQTASYERLDVFARPASPSLQLLPWRESSLDG-LGG------ 298
A P Q F P +P++QL P + S+L +GG
Sbjct: 462 ------------AQHMLPGQNQ-------FLLPGAPAVQL-PQQLSALPANVGGQILAAA 501
Query: 299 ---TGKDNLTSATLPRNYKVSPLASDR--RSDAGSYRRSLGSAGP--------------- 338
TG + + L PL+ +G++ + SA P
Sbjct: 502 APHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSL 561
Query: 339 -SGTLPRSWQPVSRIPMPPSSPQPRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLPGSPL 397
+G+LP QP P+ P + +P S + L G + P +
Sbjct: 562 AAGSLPTQSQPA------PAGPAATTVLQGVTLPPSAVAMLNTP---DGLVQPATPAAAT 612
Query: 398 FTRAPPPKLQPQPQPQPQPQSQPQPQLPPQPQTQ--PQTPTPAPQHPQQTWPPVNEGPPK 455
AP +QP PQ P S P P QPQ Q PQ PTP P Q P P
Sbjct: 613 GEAAPVLTVQPAPQAPPAV-STPLPLGLQQPQAQQPPQAPTPQAAAPPQATTP----QPS 667
Query: 456 PPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPALPPEAQSVPELEEVARVLA 515
P PE + G + + + L R Q L E P L A V+
Sbjct: 668 PGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEG---PHLSVPASVIV 724
Query: 516 EIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPELSPITEGSEA 575
P P Q PA A P + G GP P+ + SP
Sbjct: 725 SAPPPA-------QDPAPATPVA--------------KGAGLGPQAPDSQASPAPAPQIP 763
Query: 576 RAGP---PAPA--------------PPAPIPPPAPSQSSPPEQPQSM 605
A P P P+ P P P P S PP +PQS+
Sbjct: 764 AAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSV 810
Score = 57.8 bits (138), Expect = 4e-08
Identities = 139/574 (24%), Positives = 190/574 (33%), Gaps = 123/574 (21%)
Query: 54 PAPPGPQA-----GPPSRPPRYSSSSIPEPFGSRGSPRKAATDGADTPFGRSESAPTLHP 108
PAP GP A G P + + P+ +P AA G P + AP P
Sbjct: 572 PAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATP--AAATGEAAPVLTVQPAPQAPP 629
Query: 109 Y--SPLSPKG--RPSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAGSS-----LGRAPSP 159
+PL P G +P + + P P A + +AT+P+P G SS LG+ PS
Sbjct: 630 AVSTPL-PLGLQQPQAQQPPQAPTPQA-AAPPQATTPQPSP--GLASSPEKIVLGQPPSA 685
Query: 160 RP-----------------GPGPLRQQGP--PTPFDFLGRAGSPRGSPLAEGPQAFFPER 200
P PL +GP P + A P P P A
Sbjct: 686 TPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGL 745
Query: 201 GP-SPRPPATAYDAPASAFGSSLLGSGGSAFAPPLRAQDDLTLRRRPPKAWNESDLDVAY 259
GP +P A+ AP + L G G S+ +P L Q L + L +
Sbjct: 746 GPQAPDSQASPAPAPQIPAAAPLKGPGPSS-SPSLPHQAPLG---------DSPHLPSPH 795
Query: 260 EKKPSQTASYERLDVFARPASPSLQLLPWRES--SLDGLGGTGKDNLTSATLPRNYKVSP 317
+P V P+ P L P ++ +L G+ + V P
Sbjct: 796 PTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGI----------FVIQNQLGVPP 845
Query: 318 LASDRRSDAGSYRRSLGSAGPSGTLPRSWQPVSRIPMPPSSPQPRG----APRQRPIPLS 373
AS+ P+ T P QP P+ P S P G AP P S
Sbjct: 846 PASN----------------PAPTAPGPPQP----PLRPQSQPPEGPLPPAPHLPPSSTS 885
Query: 374 MIFKLQNAFWEHGASRAMLPGSPLFTRAPPPKLQPQPQPQPQPQ----SQPQPQLPPQPQ 429
A +SR P F PP P P P P +P PP P+
Sbjct: 886 SAV----ASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPR 941
Query: 430 TQPQTPTPAPQHPQ-----QTWPPVNEG----------PPKPPTELEPEPEIEGLLTPVL 474
T TP P PQ + + V G P P T P + VL
Sbjct: 942 TFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGP-LTSPAASVL 1000
Query: 475 EAGDVDEG--------PVARPLSPTRLQPALPPE----AQSVPELEEVARVLAEIPRPLK 522
+G G P P++ T L P LP E A ++P L VA+ + P
Sbjct: 1001 VSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTL-NVAKAASSGPGKPS 1059
Query: 523 RRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGG 556
+ + PPT + + H+H G
Sbjct: 1060 GLQYESKLSGLKKPPTLQPSKEACFLEHLHKHQG 1093
Score = 47.4 bits (111), Expect = 6e-05
Identities = 52/187 (27%), Positives = 70/187 (37%), Gaps = 20/187 (10%)
Query: 47 ESLWSDSPAPPGPQAGPPSRPPRYSSSSIPEPFGSRGSPRKAATDGADTP---------F 97
+S S +PAP P A P P SS S+P SP + P
Sbjct: 751 DSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSV 810
Query: 98 GRSESAPTLHPYSPLSPKGRPSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRAP 157
R S P LHP P P+ P+ P +++ + G A++P P A L
Sbjct: 811 SRPPSEPPLHPCPP--PQAPPTLP--GIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQS 866
Query: 158 SPRPGPGPLRQQGPPTPFDFLGRAGSPRGSPL-----AEGPQAFFPERGP--SPRPPATA 210
P GP P PP+ + S S L ++ F P +GP SP PP T
Sbjct: 867 QPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTL 926
Query: 211 YDAPASA 217
+ P A
Sbjct: 927 HLVPEPA 933
Score = 37.0 bits (84), Expect = 0.075
Identities = 82/349 (23%), Positives = 114/349 (32%), Gaps = 87/349 (24%)
Query: 338 PSGTLPRSWQPVSRIPMPPSSP------QPRGAPRQRPIPLSMIFKLQNAFWEHGASRAM 391
P+G LP ++ P P+ +P P+Q P ++ F +
Sbjct: 355 PAGVLPPKLYQLTPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGK----AGQNVV 410
Query: 392 LPGSP-------LFTRAPPPKLQPQPQPQPQPQSQP----------------QPQLPPQP 428
L G P +F + P P P S+P Q LP Q
Sbjct: 411 LSGFPAPALQANVFKQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQN 470
Query: 429 QTQPQTPTPAPQHPQQTWP-PVNEG-------PPKPPTELEPEPEIEGLLTPVLEAGDVD 480
Q PA Q PQQ P N G P +L P +LT AG +
Sbjct: 471 QFL-LPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANP----ILTNQNLAGPLS 525
Query: 481 EGPVARPLS-----------PTRL-QPAL------------PPEAQSVPELEEVARVLAE 516
GPV P S P ++ QPAL P ++Q P VL
Sbjct: 526 LGPVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQG 585
Query: 517 IPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPELSPITEG---S 573
+ P + + P T + L + P P P +P+ G
Sbjct: 586 VTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQ---PAPQAPPAVSTPLPLGLQQP 642
Query: 574 EARAGPPAPAPPAPIPP------PAPSQSSPPE-----QPQSMEMRSVL 611
+A+ P AP P A PP P+P +S PE QP S ++L
Sbjct: 643 QAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAIL 691
Score = 34.7 bits (78), Expect = 0.37
Identities = 53/219 (24%), Positives = 71/219 (32%), Gaps = 21/219 (9%)
Query: 393 PGSPLFTRAPPPKLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTP-APQHPQQTWPPVNE 451
P + L PPP+ P P P Q P P+ +P P P+ P + N
Sbjct: 1336 PPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRENV 1395
Query: 452 GPPKPPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPT------RLQPALPPE----- 500
G P P G P+ D + R L+ R+ PPE
Sbjct: 1396 GGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPAASA 1455
Query: 501 AQSVPELEEVARVLAEIPRPLKRRGSMEQAPAVALPP---THKKQYQQIISRLFHRHGGP 557
AQ + + A L R ++QA + P T + Q I + + P
Sbjct: 1456 AQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAP 1515
Query: 558 GPGGPEPELSPITEGSEARAGPPAPAPPAPIPPPAPSQS 596
G P P A AG PA PP P P S
Sbjct: 1516 G-RTPAPSYP-----HAASAGTPASPPPLHRPEAYPPSS 1548
Score = 31.6 bits (70), Expect = 3.2
Identities = 78/358 (21%), Positives = 112/358 (31%), Gaps = 45/358 (12%)
Query: 128 QPDAYGSLDRATSPRPRAFDGAGSSL-GRAPSPRPGPGPLRQQGPPTPFDFLGRAGSPRG 186
+PD Y S R+ P A G L G P PG Q P P + R G G
Sbjct: 1197 KPDEYVSSSRSLG-LPIAASSEGHRLPGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGG 1255
Query: 187 SPLAEGPQAF-----------------FPERGPSP---RPPATAYDAPASAFGSSL--LG 224
SP +A E GP P RPP Y+A S G L
Sbjct: 1256 SPSVTWARASSSLSSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEA-RSRIGLKLKIKQ 1314
Query: 225 SGGSAFAPPLRAQDDLTLRRRPPKAWNESDLDVAYEKKPSQTASYERLDVFARPASPSLQ 284
G + A D + PP ++ P T PA+P +
Sbjct: 1315 EAGLSKVVHNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERK 1374
Query: 285 ---------LLPWRESSLDGLGGTGKDNLTSATLPRNYKVSPLASDRRSDAGSYRRSLGS 335
LP R++ + +GG G T A R +PL + R L +
Sbjct: 1375 PLGTAPHCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAA 1434
Query: 336 AGPSGTLPRSWQPVSRIPMP---PSSPQPRGAP--RQRPIPLSMIFKLQNAFWEHGASRA 390
+Q + + P P S+ Q G P +P + K ++ + + +
Sbjct: 1435 VE-----DELYQRMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSS 1489
Query: 391 MLPGSPLFTRAPPPKLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPP 448
P T + Q P P P P + +P P H + +PP
Sbjct: 1490 DSPQDDTLTEHLQSAIDSILNLQQAPGRTPAPSY-PHAASAGTPASPPPLHRPEAYPP 1546
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 73.6 bits (179), Expect = 7e-13
Identities = 77/276 (27%), Positives = 103/276 (37%), Gaps = 63/276 (22%)
Query: 395 SPLFTRAPPPKLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPA---------------- 438
+P+ + PPP QP P P PQ Q QP P PP P + PQ PA
Sbjct: 751 APVPQQPPPPPQQPPPPPPPQQQQQPPP--PPPPPSMPQQAAPAMKSSPPPFIATQVPVL 808
Query: 439 -PQHPQQTWPPVNEGPPKPPTELEPEPEI--------EGLLTPVLEAGDVDEGPV----- 484
PQ P + P+ G P P+PE+ E P L V P
Sbjct: 809 EPQLPGSVFDPI--GHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNAL 866
Query: 485 -ARPLSPTRLQPALPPEAQSVPELEEVARVLAEIPRPLKRRGSMEQAPAVAL-------P 536
+P P+ ALPP+ P + +P+P M Q P V L P
Sbjct: 867 PQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQP-----PMAQPPQVLLEDEEPPAP 921
Query: 537 PTHKKQYQQIISRLFHRHGGPGP--------GGPEPELSPITEGS---EARAGPPAPAPP 585
P Q Q + +L + P P P P L P S + + PP P PP
Sbjct: 922 PLTSMQMQLYLQQL-QKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPP 980
Query: 586 APIPPPAPSQSSPPEQP---QSMEMRSVLRKAGSPR 618
P PPP Q PP +P Q M+ + +++ P+
Sbjct: 981 QPQPPP-QQQHQPPPRPVHLQPMQFSTHIQQPPPPQ 1015
Score = 70.5 bits (171), Expect = 6e-12
Identities = 92/387 (23%), Positives = 139/387 (35%), Gaps = 61/387 (15%)
Query: 270 ERLDVFARPASPSLQLLPWRESSLDGLGGTGKDNLTSATLPRNYKVSPLASDRRSDAGSY 329
E++DV A + ESS + +D+ T K P ++ +
Sbjct: 684 EKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHH 743
Query: 330 RRSLGSAGPSGTLPRSWQPVSRIPMPPSSPQPRGAPRQRPIPLSMIFKLQNAFWEHGASR 389
++ + P +P+ P + P PP PQ + P P P SM A+
Sbjct: 744 QQMQQAPAP---VPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSM---------PQQAAP 791
Query: 390 AMLPGSPLFTRAPPPKLQPQ-PQPQPQPQSQ--------PQPQLPPQPQTQPQTPTPAP- 439
AM P F P L+PQ P P PQP+LPP P+ TP
Sbjct: 792 AMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHL 851
Query: 440 -QHPQQTWPPVNEGPPKPPTE-------LEPEPEIEGLLTPVL-EAGDVDEGPVARPLSP 490
QH + P ++ P+ P+ L P+P ++P L + + + P+A+P P
Sbjct: 852 NQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQP--P 909
Query: 491 TRL----QPALPPEAQSVPELEEVARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQI 546
L +P PP +L + P PL ++ P LPP QQ
Sbjct: 910 QVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQ 969
Query: 547 ISRLFHRHGGPGPGGPEPELSPITEGSEARAGPPAPA---------------PPAPIPPP 591
+ + P P P+P+ P + PP P PP PP
Sbjct: 970 LQQQ-----PPPPPPPQPQPPP----QQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPP 1020
Query: 592 APSQSSPPEQPQSMEMRSVLRKAGSPR 618
P P PQ + + V++ SPR
Sbjct: 1021 HPPPGQQPPPPQPAKPQQVIQHHHSPR 1047
Score = 67.4 bits (163), Expect = 5e-11
Identities = 72/303 (23%), Positives = 107/303 (35%), Gaps = 39/303 (12%)
Query: 352 IPMPPSSPQPRGAPRQRPIPLSMIFKLQNAFWEHGASRA-----MLPGSPLFTRAPPP-- 404
+P PP + P+ P + +Q + + +LP + ++ PPP
Sbjct: 900 LPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLP 959
Query: 405 -----------KLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPPVNEGP 453
+ QP P P PQPQ PQ Q P P+ P H QQ PP + P
Sbjct: 960 PPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQP 1019
Query: 454 PKPPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPALPPEAQSVPELEEVARV 513
P PP +P P V++ + P S L+ A P P++ + +
Sbjct: 1020 PHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSL 1079
Query: 514 LAEIP-----RPLK---RRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGP-GPGGPE- 563
+ P +P K R S+ Q + + K I S F P P PE
Sbjct: 1080 THQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPES 1139
Query: 564 ----------PELSPITEGSEARAGPPAPAPPAPIPPPAPSQSSPPEQPQSMEMRSVLRK 613
PE+ P+ G P APP P P Q P+ P + + ++
Sbjct: 1140 IKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPP-PGAPDKDKQKQEPKTPVAPKKDLKIKN 1198
Query: 614 AGS 616
GS
Sbjct: 1199 MGS 1201
Score = 51.2 bits (121), Expect = 4e-06
Identities = 54/195 (27%), Positives = 76/195 (38%), Gaps = 24/195 (12%)
Query: 327 GSYRRSLGSAGPS-GTLPRSWQPVSRIPMPPSSPQPRGAPRQR-PIPLSMIFKLQNAFWE 384
G R+ G+A P T+P + Q + P +PQP P Q P P +
Sbjct: 180 GRGRKETGTAKPGVSTVPNTTQ--ASTPPQTQTPQPNPPPVQATPHPFPAVTP---DLIV 234
Query: 385 HGASRAMLPGSPLFTRAPPPKLQPQPQPQPQPQSQPQPQLPP--QPQTQPQTPTPAPQHP 442
++P PL T PP + PQPQP P P QP PP QP +
Sbjct: 235 QTPVMTVVPPQPLQT---PPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRK 291
Query: 443 QQTWPPVNEGPPKPPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPALPPEAQ 502
T P P P L PEP+ L G E +RP+ P + P++Q
Sbjct: 292 ADTTTPTTIDPIHEPPSLPPEPKTTKL-------GQRRES--SRPVKPPKKD---VPDSQ 339
Query: 503 SVPELEEVARVLAEI 517
P E+ ++V ++
Sbjct: 340 QHPAPEKSSKVSEQL 354
Score = 43.1 bits (100), Expect = 0.001
Identities = 44/175 (25%), Positives = 70/175 (40%), Gaps = 31/175 (17%)
Query: 427 QPQTQPQTPTPAPQHPQQTWPPVNEGPPKPPTELEPEPEIEGLLTPVLEAGDVDEGPVAR 486
Q T PQT TP P PP + P P + P+ ++ TPV+ V P+
Sbjct: 201 QASTPPQTQTPQPN------PPPVQATPHPFPAVTPDLIVQ---TPVMTV--VPPQPLQT 249
Query: 487 PLSPTRLQPALPPEAQSVPELEEVARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQI 546
P P QP PP A + ++ ++A P+P+K + +++ P T ++
Sbjct: 250 P-PPVPPQPQ-PPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHE-- 305
Query: 547 ISRLFHRHGGPGPGGPEPELSPITEGSEARAGPPAPAPPAPIPP----PAPSQSS 597
P PEP+ + + G + P P +P PAP +SS
Sbjct: 306 ----------PPSLPPEPKTTKL--GQRRESSRPVKPPKKDVPDSQQHPAPEKSS 348
Score = 39.3 bits (90), Expect = 0.015
Identities = 44/174 (25%), Positives = 60/174 (34%), Gaps = 24/174 (13%)
Query: 56 PPGPQAGPPSRPPRYSSSSIPEPFGSRGSPRKA--ATDGADTPFGRSESAPTLHPYSPLS 113
PP P PP PP P P P++A A + PF ++ P L P P S
Sbjct: 757 PPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQ-VPVLEPQLPGS 815
Query: 114 -----------------PKGRPSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRA 156
P+ P P+ P + P L++ P A A
Sbjct: 816 VFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPP---HLNQHAVVSPPALHNALPQQPSR 872
Query: 157 PSPRPGPGPLRQQGPPTPFDFLGRAGSPRGSPLAEGPQAFFPERGPSPRPPATA 210
PS R P + PP L + P+A+ PQ + P P PP T+
Sbjct: 873 PSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEP-PAPPLTS 925
Score = 34.7 bits (78), Expect = 0.37
Identities = 40/170 (23%), Positives = 57/170 (33%), Gaps = 31/170 (18%)
Query: 56 PPGPQAGPPSRPPRYSSSSIPEPFGSRGSPRKAATDGADTPFGRSESAPT---------L 106
PP P P P + +P+P P + + + P S +
Sbjct: 881 PPKPARPPAVSPALTQTPLLPQP--PMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKV 938
Query: 107 HPYSPLSPKGRPSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRAPSPRPGPGPL 166
P +PL P + S + P L P + S+ + +P P P+P P P
Sbjct: 939 QPPTPLLPSVKVQS-QPPPPLPPPPHPSVQQQLQQQPPP----------PPPPQPQPPPQ 987
Query: 167 RQQGPP------TPFDFLGRAGSPRGSPLAEGPQAFFPERGPSPRPPATA 210
+Q PP P F P P +G Q P G P PP A
Sbjct: 988 QQHQPPPRPVHLQPMQFSTHIQQP---PPPQGQQPPHPPPGQQPPPPQPA 1034
Score = 32.3 bits (72), Expect = 1.8
Identities = 20/43 (46%), Positives = 24/43 (55%), Gaps = 8/43 (18%)
Query: 580 PAPAPPAPIPPPAPS----QSSPP---EQPQSME-MRSVLRKA 614
P P PP P PPPAP+ QS PP PQ ++ + V RKA
Sbjct: 250 PPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKA 292
>gi|219842212 protein phosphatase 1, regulatory (inhibitor) subunit
12A isoform a [Homo sapiens]
Length = 1030
Score = 73.2 bits (178), Expect = 9e-13
Identities = 40/115 (34%), Positives = 61/115 (53%), Gaps = 1/115 (0%)
Query: 618 RKARRARLNPLVLLLDAALTGELEVVQQAVKEMNDPSQPNEEGITALHNAICGANYSIVD 677
R+ + + + + L A +G+ + V + + D + N +G+TALH A N +V
Sbjct: 31 RQKTKVKFDDGAVFLAACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVK 90
Query: 678 FLITAGANVNSPDSHGWTPLHCAASCNDTVICMALVQHGAAIFATTLSDGATAFE 732
FL+ GAN+N PD+ GW PLH AASC I L+ GA + A S+G T +
Sbjct: 91 FLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVN-SEGDTPLD 144
Score = 49.7 bits (117), Expect = 1e-05
Identities = 34/103 (33%), Positives = 46/103 (44%), Gaps = 7/103 (6%)
Query: 658 EEGITALHNAICGANYSIVDFLITAGANVNSPDSHGWTPLHCAASCNDTVICMALVQHGA 717
+ G TALH A ++ LI AG +VN D GWTPLH AA C LV +
Sbjct: 197 KSGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDN-L 255
Query: 718 AIFATTLSDGATAFEKCDPYREGYADCATYLADVEQSMGLMNS 760
G TAF+ D D YL ++++ L++S
Sbjct: 256 CDMEMVNKVGQTAFDVAD------EDILGYLEELQKKQNLLHS 292
Score = 42.0 bits (97), Expect = 0.002
Identities = 26/78 (33%), Positives = 41/78 (52%)
Query: 623 ARLNPLVLLLDAALTGELEVVQQAVKEMNDPSQPNEEGITALHNAICGANYSIVDFLITA 682
A ++ L L A + +++V+ V+ + +QP+ EG LH A I +FLI
Sbjct: 69 ANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQ 128
Query: 683 GANVNSPDSHGWTPLHCA 700
GA+V + +S G TPL A
Sbjct: 129 GAHVGAVNSEGDTPLDIA 146
>gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit
12A isoform a [Homo sapiens]
Length = 1030
Score = 73.2 bits (178), Expect = 9e-13
Identities = 40/115 (34%), Positives = 61/115 (53%), Gaps = 1/115 (0%)
Query: 618 RKARRARLNPLVLLLDAALTGELEVVQQAVKEMNDPSQPNEEGITALHNAICGANYSIVD 677
R+ + + + + L A +G+ + V + + D + N +G+TALH A N +V
Sbjct: 31 RQKTKVKFDDGAVFLAACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVK 90
Query: 678 FLITAGANVNSPDSHGWTPLHCAASCNDTVICMALVQHGAAIFATTLSDGATAFE 732
FL+ GAN+N PD+ GW PLH AASC I L+ GA + A S+G T +
Sbjct: 91 FLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVN-SEGDTPLD 144
Score = 49.7 bits (117), Expect = 1e-05
Identities = 34/103 (33%), Positives = 46/103 (44%), Gaps = 7/103 (6%)
Query: 658 EEGITALHNAICGANYSIVDFLITAGANVNSPDSHGWTPLHCAASCNDTVICMALVQHGA 717
+ G TALH A ++ LI AG +VN D GWTPLH AA C LV +
Sbjct: 197 KSGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDN-L 255
Query: 718 AIFATTLSDGATAFEKCDPYREGYADCATYLADVEQSMGLMNS 760
G TAF+ D D YL ++++ L++S
Sbjct: 256 CDMEMVNKVGQTAFDVAD------EDILGYLEELQKKQNLLHS 292
Score = 42.0 bits (97), Expect = 0.002
Identities = 26/78 (33%), Positives = 41/78 (52%)
Query: 623 ARLNPLVLLLDAALTGELEVVQQAVKEMNDPSQPNEEGITALHNAICGANYSIVDFLITA 682
A ++ L L A + +++V+ V+ + +QP+ EG LH A I +FLI
Sbjct: 69 ANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQ 128
Query: 683 GANVNSPDSHGWTPLHCA 700
GA+V + +S G TPL A
Sbjct: 129 GAHVGAVNSEGDTPLDIA 146
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 72.8 bits (177), Expect = 1e-12
Identities = 82/337 (24%), Positives = 117/337 (34%), Gaps = 70/337 (20%)
Query: 292 SLDGLGGTGKDNLTSATLPRNYKVSPLASDRRSDAGSYRRSLGSAGPSGTLPRSWQPVSR 351
S G G G L A +P+ + +R +D+G R L LP + S
Sbjct: 91 SFGGGGPPGLGGLFQAGMPKLRSTA----NRDNDSGGSRPPL--------LPPGGRSTSA 138
Query: 352 IPMPPSSPQPRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLPGSPLFTRAPPPKLQPQPQ 411
P P S P + P+P PG R+ PP+ Q
Sbjct: 139 KPFSPPS-----GPGRFPVPS--------------------PGH----RSGPPEPQRNRM 169
Query: 412 PQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPPVNEGPPKPPTELEPEPEIEGLLT 471
P P+P +P P P P TP P P P G P+ P+ P G
Sbjct: 170 PPPRPDVGSKPDSIPPPV--PSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRG 227
Query: 472 PVLEAGDVDEGPVARPLSPTRLQPALPPEAQSVPELEEVARVLAEIPRPLKRRGSMEQAP 531
L G + + P++ SP +P LPP + + P P+ R S+ +
Sbjct: 228 TALGGGSIRQSPLSSS-SPFSNRPPLPPTPSRALDDKPPPP-----PPPVGNRPSIHREA 281
Query: 532 AVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPELSPITEGSEARAGPPAPAPPAPIPPP 591
PP + K P P P P S ++A PP P P P PPP
Sbjct: 282 VPPPPPQNNKP--------------PVPSTPRPSAS-------SQAPPPPPPPSRPGPPP 320
Query: 592 APSQSSPPEQPQSMEMRSVLRKAGSPRKARRARLNPL 628
P SS ++ + R++ + +P R PL
Sbjct: 321 LPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPL 357
Score = 53.9 bits (128), Expect = 6e-07
Identities = 100/385 (25%), Positives = 121/385 (31%), Gaps = 81/385 (21%)
Query: 96 PFGRSESAPTLHPYS-----PLSPKGRPSSPRTPLYLQ-----PDAYGSLDRATSPRPRA 145
P GRS SA P S P+ G S P P + PD D P P
Sbjct: 131 PGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPST 190
Query: 146 FDGAGSSLGRAPSPRPGPGPLRQQGP-PTPFDFLGR------AGSPRGSPLAEGPQAFFP 198
SS SP P PG RQ P PTP F G GS R SPL+ F
Sbjct: 191 PRPIQSSPHNRGSP-PVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSP--FS 247
Query: 199 ERGPSPRPPATAYDAPASAFGSSLLGSGGSAFAPPLRAQDDLTLRRRPPKAWNESDLDVA 258
R P P P+ A D PP+ + + PP + V
Sbjct: 248 NRPPLPPTPSRALDDKPPPP------------PPPVGNRPSIHREAVPPPPPQNNKPPVP 295
Query: 259 YEKKPSQTASYERLDVFARPASPSLQLLPWRESSLDGLGGTGKDNLTSATLPRNYKVSPL 318
+PS AS + P+ P LP S D +P
Sbjct: 296 STPRPS--ASSQAPPPPPPPSRPGPPPLPPSSSGNDE--------------------TPR 333
Query: 319 ASDRRSDAGSYRRSLGSAGPSGTLPRSWQPVSRIPMPPSSPQPRGAPRQRPIPLSMIFKL 378
R S L S G SG LP P R P P P R P P P+S
Sbjct: 334 LPQRNLSLSSSTPPLPSPGRSGPLPPP--PSERPPPPVRDPPGRSGPLPPPPPVS----- 386
Query: 379 QNAFWEHGASRAMLPGSPLFTRAPPPKLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPA 438
+G++ LP +P P P+S P+P LP P P+
Sbjct: 387 -----RNGSTSRALPATPQL---------PSRSGVDSPRSGPRPPLP------PDRPSAG 426
Query: 439 PQHPQQTWPPVNEGPPKPPTELEPE 463
P + G P E E E
Sbjct: 427 APPPPPPSTSIRNGFQDSPCEDEWE 451
Score = 40.0 bits (92), Expect = 0.009
Identities = 92/387 (23%), Positives = 133/387 (34%), Gaps = 73/387 (18%)
Query: 52 DSPAPPGPQAGPPSRPPRYSSSSIPEPFGSRGSPRKAATDGADTPF----GRSESAPTLH 107
DS PP P P + ++ S P P G PR+ + PF G + ++
Sbjct: 181 DSIPPPVPSTPRPIQSSPHNRGSPPVP----GGPRQPSPGPTPPPFPGNRGTALGGGSIR 236
Query: 108 PYSPLSPKGRPSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRAPSPRPGPGPLR 167
SPLS P S R P L P +LD P P G S+ R P P P +
Sbjct: 237 -QSPLS-SSSPFSNRPP--LPPTPSRALDDKPPPPPPPV-GNRPSIHREAVPPPPP---Q 288
Query: 168 QQGPPTPFDFLGRAGSPRGSPLAEGPQAFFP--ERGPSPRPPATAYDAPASAFGSSLLGS 225
PP P +PR S ++ P P GP P PP+++ + L
Sbjct: 289 NNKPPVP-------STPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSL 341
Query: 226 GGSAFAPPLRAQDDLTLRRRPPKAWNESDLDVAYEKKPSQTASYERLDVFARPASPSLQL 285
S PPL P L ++P P ++
Sbjct: 342 SSS--TPPL------------PSPGRSGPLPPPPSERP----------------PPPVRD 371
Query: 286 LPWRESSLDGLGGTGKDNLTSATLPRNYKVSPLASDRRSDAGSYRRSLGSAGPSGTLPRS 345
P R L ++ TS LP ++ RS S R +GP LP
Sbjct: 372 PPGRSGPLPPPPPVSRNGSTSRALPATPQL-----PSRSGVDSPR-----SGPRPPLPPD 421
Query: 346 WQPVSRIPMPPSSPQPRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLPGSPLF--TRAPP 403
P PP S R + P + ++ F+ H S + P P T++ P
Sbjct: 422 RPSAGAPPPPPPSTSIRNGFQDSPCE----DEWESRFYFHPIS-DLPPPEPYVQTTKSYP 476
Query: 404 PKL-QPQPQPQPQPQSQPQPQLPPQPQ 429
KL + + + + + P LPP P+
Sbjct: 477 SKLARNESRSGSNRRERGAPPLPPIPR 503
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 72.8 bits (177), Expect = 1e-12
Identities = 82/337 (24%), Positives = 117/337 (34%), Gaps = 70/337 (20%)
Query: 292 SLDGLGGTGKDNLTSATLPRNYKVSPLASDRRSDAGSYRRSLGSAGPSGTLPRSWQPVSR 351
S G G G L A +P+ + +R +D+G R L LP + S
Sbjct: 91 SFGGGGPPGLGGLFQAGMPKLRSTA----NRDNDSGGSRPPL--------LPPGGRSTSA 138
Query: 352 IPMPPSSPQPRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLPGSPLFTRAPPPKLQPQPQ 411
P P S P + P+P PG R+ PP+ Q
Sbjct: 139 KPFSPPS-----GPGRFPVPS--------------------PGH----RSGPPEPQRNRM 169
Query: 412 PQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPPVNEGPPKPPTELEPEPEIEGLLT 471
P P+P +P P P P TP P P P G P+ P+ P G
Sbjct: 170 PPPRPDVGSKPDSIPPPV--PSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRG 227
Query: 472 PVLEAGDVDEGPVARPLSPTRLQPALPPEAQSVPELEEVARVLAEIPRPLKRRGSMEQAP 531
L G + + P++ SP +P LPP + + P P+ R S+ +
Sbjct: 228 TALGGGSIRQSPLSSS-SPFSNRPPLPPTPSRALDDKPPPP-----PPPVGNRPSIHREA 281
Query: 532 AVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPELSPITEGSEARAGPPAPAPPAPIPPP 591
PP + K P P P P S ++A PP P P P PPP
Sbjct: 282 VPPPPPQNNKP--------------PVPSTPRPSAS-------SQAPPPPPPPSRPGPPP 320
Query: 592 APSQSSPPEQPQSMEMRSVLRKAGSPRKARRARLNPL 628
P SS ++ + R++ + +P R PL
Sbjct: 321 LPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPL 357
Score = 53.9 bits (128), Expect = 6e-07
Identities = 100/385 (25%), Positives = 121/385 (31%), Gaps = 81/385 (21%)
Query: 96 PFGRSESAPTLHPYS-----PLSPKGRPSSPRTPLYLQ-----PDAYGSLDRATSPRPRA 145
P GRS SA P S P+ G S P P + PD D P P
Sbjct: 131 PGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPST 190
Query: 146 FDGAGSSLGRAPSPRPGPGPLRQQGP-PTPFDFLGR------AGSPRGSPLAEGPQAFFP 198
SS SP P PG RQ P PTP F G GS R SPL+ F
Sbjct: 191 PRPIQSSPHNRGSP-PVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSP--FS 247
Query: 199 ERGPSPRPPATAYDAPASAFGSSLLGSGGSAFAPPLRAQDDLTLRRRPPKAWNESDLDVA 258
R P P P+ A D PP+ + + PP + V
Sbjct: 248 NRPPLPPTPSRALDDKPPPP------------PPPVGNRPSIHREAVPPPPPQNNKPPVP 295
Query: 259 YEKKPSQTASYERLDVFARPASPSLQLLPWRESSLDGLGGTGKDNLTSATLPRNYKVSPL 318
+PS AS + P+ P LP S D +P
Sbjct: 296 STPRPS--ASSQAPPPPPPPSRPGPPPLPPSSSGNDE--------------------TPR 333
Query: 319 ASDRRSDAGSYRRSLGSAGPSGTLPRSWQPVSRIPMPPSSPQPRGAPRQRPIPLSMIFKL 378
R S L S G SG LP P R P P P R P P P+S
Sbjct: 334 LPQRNLSLSSSTPPLPSPGRSGPLPPP--PSERPPPPVRDPPGRSGPLPPPPPVS----- 386
Query: 379 QNAFWEHGASRAMLPGSPLFTRAPPPKLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPA 438
+G++ LP +P P P+S P+P LP P P+
Sbjct: 387 -----RNGSTSRALPATPQL---------PSRSGVDSPRSGPRPPLP------PDRPSAG 426
Query: 439 PQHPQQTWPPVNEGPPKPPTELEPE 463
P + G P E E E
Sbjct: 427 APPPPPPSTSIRNGFQDSPCEDEWE 451
Score = 40.0 bits (92), Expect = 0.009
Identities = 92/387 (23%), Positives = 133/387 (34%), Gaps = 73/387 (18%)
Query: 52 DSPAPPGPQAGPPSRPPRYSSSSIPEPFGSRGSPRKAATDGADTPF----GRSESAPTLH 107
DS PP P P + ++ S P P G PR+ + PF G + ++
Sbjct: 181 DSIPPPVPSTPRPIQSSPHNRGSPPVP----GGPRQPSPGPTPPPFPGNRGTALGGGSIR 236
Query: 108 PYSPLSPKGRPSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRAPSPRPGPGPLR 167
SPLS P S R P L P +LD P P G S+ R P P P +
Sbjct: 237 -QSPLS-SSSPFSNRPP--LPPTPSRALDDKPPPPPPPV-GNRPSIHREAVPPPPP---Q 288
Query: 168 QQGPPTPFDFLGRAGSPRGSPLAEGPQAFFP--ERGPSPRPPATAYDAPASAFGSSLLGS 225
PP P +PR S ++ P P GP P PP+++ + L
Sbjct: 289 NNKPPVP-------STPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSL 341
Query: 226 GGSAFAPPLRAQDDLTLRRRPPKAWNESDLDVAYEKKPSQTASYERLDVFARPASPSLQL 285
S PPL P L ++P P ++
Sbjct: 342 SSS--TPPL------------PSPGRSGPLPPPPSERP----------------PPPVRD 371
Query: 286 LPWRESSLDGLGGTGKDNLTSATLPRNYKVSPLASDRRSDAGSYRRSLGSAGPSGTLPRS 345
P R L ++ TS LP ++ RS S R +GP LP
Sbjct: 372 PPGRSGPLPPPPPVSRNGSTSRALPATPQL-----PSRSGVDSPR-----SGPRPPLPPD 421
Query: 346 WQPVSRIPMPPSSPQPRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLPGSPLF--TRAPP 403
P PP S R + P + ++ F+ H S + P P T++ P
Sbjct: 422 RPSAGAPPPPPPSTSIRNGFQDSPCE----DEWESRFYFHPIS-DLPPPEPYVQTTKSYP 476
Query: 404 PKL-QPQPQPQPQPQSQPQPQLPPQPQ 429
KL + + + + + P LPP P+
Sbjct: 477 SKLARNESRSGSNRRERGAPPLPPIPR 503
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 72.4 bits (176), Expect = 2e-12
Identities = 144/631 (22%), Positives = 219/631 (34%), Gaps = 138/631 (21%)
Query: 32 LDTAAAKVDELTKQLESLWSDSPAPPGPQAGPPSRPPRYSSSSIPEPFGSRGSPRKAATD 91
+ + A +E TK+ + + + P G P + P P+P + P +
Sbjct: 179 ISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQP-------PKPIPKQQGPGRDPLQ 231
Query: 92 GADTPFGRSESAPTLHPYSP-------LSPKGRPSSPRTPLYLQPDAYGSLDRATSPRPR 144
TP S P P P P + L LQ DA + P+ +
Sbjct: 232 QDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDA-------SRPQTK 284
Query: 145 AFDGAGSSLGRAPSPRPGPGPLRQQGPPTPFDFLGRAGSPRGSPLAEGPQAFFPERGPSP 204
D + P P P++Q PTP G P A+ P + GP+
Sbjct: 285 QADIVRGESVKPSLPSPSKPPIQQ---PTP-----------GKPPAQQPGHEKSQPGPA- 329
Query: 205 RPPATAYDAPASAFGSSLLGSGGSAFAPPLRAQDDLTLRRRPPKAWNESDLDVAYEKKPS 264
+PPA S L G+ PP++ PP + K P+
Sbjct: 330 KPPAQP-----SGLTKPLAQQPGTV-KPPVQ----------PPGTTKPPAQPLGPAKPPA 373
Query: 265 QTASYERLDVFARPASPSLQLLPWRESSLDGLGGTGKDNLTSATLPRNYKVSPLASDRRS 324
Q E+ +P +L P G GK T A P
Sbjct: 374 QQTGSEKPSS-EQPGPKALAQPP----------GVGK---TPAQQP-------------- 405
Query: 325 DAGSYRRSLGSAGPSGTLPRSWQPVSRIP---MPPSSPQPRGAPRQRP----IPLSMIFK 377
G A P + +P+++ P P +P P P Q+P IP
Sbjct: 406 ---------GPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGP 456
Query: 378 LQNAFWEHGASRAMLPGSPLFTRAPPPKLQP---QPQPQPQPQSQPQPQLPPQPQTQPQT 434
+ + + G ++ P S L A PP QP +P PQ ++P Q P + PQ
Sbjct: 457 GKTSAQQTGPTK---PPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQ 513
Query: 435 PTPA---PQHPQQTWPPVNEGPPKPPTELEP---EPEIEGLLTPVLEAGDVDEGPVARPL 488
P PA PQ P T PP + P+ +P +P + PV + G +PL
Sbjct: 514 PGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGS------GKPL 567
Query: 489 SPTRLQP-ALPPEAQSVPE----LEEVARVLAEIPRPLKRRGSMEQAPAV----ALPP-- 537
P + P A P +Q +P+ L +L +P E V P
Sbjct: 568 QPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNP 627
Query: 538 --THKKQYQQIISRLFHRHGG---PGPGGPEPEL--SPITEGSEARAGPPAPAPPAPIPP 590
T K++ + ++ GG P P P+P+L +P+T S P P +P
Sbjct: 628 HLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKD 687
Query: 591 PAP----SQSSPPEQPQSMEMRSVLRKAGSP 617
AP S++ P++P + + L GSP
Sbjct: 688 AAPKQDLSKAPEPKKPPPLVKQPTLH--GSP 716
Score = 59.3 bits (142), Expect = 1e-08
Identities = 113/529 (21%), Positives = 188/529 (35%), Gaps = 87/529 (16%)
Query: 118 PSSPRTPLYLQPDAYGSLDRATSPRPRAFD-----GAGSSLGRAPSPRPGP--------- 163
PSSP+ L P S +SP+P+ L +AP P+ P
Sbjct: 654 PSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLH 713
Query: 164 -GPLRQQGPPTPFDFLGRAGSPRGSPLAEGPQAFFPERGPSPRPPATAYDAPASAFGSSL 222
P + P D L + P+ P Q P P+ P + L
Sbjct: 714 GSPSAKAKQPPEADSLSKPAPPK-EPSVPSEQDKAPVADDKPKQPKMVKPT------TDL 766
Query: 223 LGSGGSAFAPPL---RAQDDLTLRRRPPKAWNESDLDVAYEKKPSQTASYERLDVFARPA 279
+ S + P + + Q + PP + + ++ + + ++ + RPA
Sbjct: 767 VSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAI-PRPA 825
Query: 280 SPSLQLLPWRESSLDGLGGTGKDNLTSATLPRNY--KVSPLASDRRSDAGSYRRSLGSAG 337
S S +++ S + G D + P+ K+SP + DA + GS
Sbjct: 826 SDS-KIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSP-----KPDAKPMPK--GSPT 877
Query: 338 PSGTLPRSWQPVSRIPMPPSSPQPRGAPRQRPIPLSMIFKLQNA------------FWEH 385
P G P + Q V P P SP+P+ R+ + L I + +
Sbjct: 878 PPGPRPTAGQTV---PTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGF 934
Query: 386 GASRAMLPGSPLFTRAPPPKLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQT 445
GAS S L + A P Q P + P P PP Q P++ AP P ++
Sbjct: 935 GAS-IFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKS 993
Query: 446 WPPVNEGPPKPPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPALPPEAQSVP 505
P E +LEP+ E P ++ + ++ P P+ ++ A P +A
Sbjct: 994 IPVKKETKAPAAEKLEPKAE----QAPTVKRTETEKKP--PPIKDSKSLTAEPQKAVLPT 1047
Query: 506 ELEEVARVLAEIP--RPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPE 563
+LE+ + + P + GS + P + + +++ + G P
Sbjct: 1048 KLEKSPKPESTCPLCKTELNIGSKD--------PPNFNTCTECKNQVCNLCG----FNPT 1095
Query: 564 PELSPITEG---------------SEARAGPPAPAPPAPIPPPAPSQSS 597
P L+ I E + R PPAP+ P P P P++SS
Sbjct: 1096 PHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESS 1144
Score = 54.7 bits (130), Expect = 3e-07
Identities = 132/591 (22%), Positives = 187/591 (31%), Gaps = 86/591 (14%)
Query: 53 SPAPPGPQAGPPSRPPRYSSSSIPEPFGSRGSPRKAATDGADTPFGRSESA--PTLHPYS 110
SP+ P Q P +PP G P A G P + P + P
Sbjct: 300 SPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPP--AQPSGLTKPLAQQPGTVKPPVQPPG 357
Query: 111 PLSPKGRPSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRAPSPRPGPG--PLRQ 168
P +P P P Q + + P P+A +G+ P+ +PGP P +Q
Sbjct: 358 TTKPPAQPLGPAKPPAQQTGS--EKPSSEQPGPKAL-AQPPGVGKTPAQQPGPAKPPTQQ 414
Query: 169 QGPPTPFDFLGRAGSPRGSPLAEGPQAFFPERGPSPRPPATAYDAPASAFGSSLLGSG-- 226
G P P SP +P P G P A A G + S
Sbjct: 415 VGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLP 474
Query: 227 GSAFAPPLRAQDDLTLRRRPPKAWNESDLDVAYEKKPSQTASYERLDVFARPASPSLQLL 286
G A PP + ++P A S + + P Q PA PS Q
Sbjct: 475 GPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPG----------PAKPSPQQ- 523
Query: 287 PWRESSLDGLGGTGKDNLTSATLPRNYKVSPLASDRR-SDAGSYRRSLGSAGPSGTLPRS 345
P G+ K SA P K S S + S GS + P P +
Sbjct: 524 PGSTKPPSQQPGSAKP---SAQQPSPAKPSAQQSTKPVSQTGSGK----PLQPPTVSPSA 576
Query: 346 WQPVSRIPMPPSSPQPRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLPGSPLFT------ 399
QP S+ P +P F S +P T
Sbjct: 577 KQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWL 636
Query: 400 -------RAPPPKLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPPVNEG 452
RA L P P S PQP+L P T + + PQQT P +
Sbjct: 637 CLNCQMKRALGGDLAPVP-------SSPQPKLKTAPVTTTSAVSKSSPQPQQT-SPKKDA 688
Query: 453 PPKPPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTR---LQPALPPEAQSVPELEE 509
PK PEP+ P+++ + P A+ P L PP+ SVP ++
Sbjct: 689 APKQDLSKAPEPKKP---PPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQD 745
Query: 510 VARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPELSPI 569
A V + P+ P + P T ++ P+ S +
Sbjct: 746 KAPVADDKPK----------QPKMVKPTTDLVSSSSATTK------------PDIPSSKV 783
Query: 570 TEGSEARAGPPAPAPPAPIPPPAPSQSSPP--EQPQSMEMRSVLRKAGSPR 618
+E + PP A PSQS PP E+ + +++ R A +
Sbjct: 784 QSQAEEKTTPPLKTDSA-----KPSQSFPPTGEKVSPFDSKAIPRPASDSK 829
Score = 51.2 bits (121), Expect = 4e-06
Identities = 68/291 (23%), Positives = 109/291 (37%), Gaps = 31/291 (10%)
Query: 356 PSSPQPRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLPGSPLFTRAP----PPKLQPQPQ 411
PS P P P Q+P P + Q + A P P P P ++P Q
Sbjct: 296 PSLPSPSKPPIQQPTPGKPPAQ-QPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQ 354
Query: 412 PQ--PQPQSQPQ-PQLPPQPQT---QPQTPTPAPQHPQQT-----WPPVNEGPPKPPTEL 460
P +P +QP P PP QT +P + P P+ Q P GP KPPT+
Sbjct: 355 PPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQ 414
Query: 461 ----EPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPALPPEAQSVPELEEVARVLAE 516
+P + GL +P G + PV +P P ++ ++ + + ++
Sbjct: 415 VGTPKPLAQQPGLQSPAKAPGPT-KTPVQQP-GPGKIPAQQAGPGKTSAQQTGPTKPPSQ 472
Query: 517 IPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPELSPITEGSEAR 576
+P P K Q P A PP + + S+ PG P P+ + S +
Sbjct: 473 LPGPAK---PPPQQPGPAKPPPQQPGSAKPPSQQ------PGSTKPPPQQPGPAKPSPQQ 523
Query: 577 AGPPAPAPPAPIPPPAPSQSSPPEQPQSMEMRSVLRKAGSPRKARRARLNP 627
G P P +Q P +P + + + + GS + + ++P
Sbjct: 524 PGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSP 574
Score = 50.1 bits (118), Expect = 9e-06
Identities = 133/624 (21%), Positives = 213/624 (34%), Gaps = 144/624 (23%)
Query: 54 PAPPGPQ----AGPPSRPPRYSSSSIPEPFGSRGSPRKAATDGADTPFGRSESAPTLHPY 109
PA P PQ PPS+ P + S +P ++ S +++ + T G+ PT+ P
Sbjct: 516 PAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPS 575
Query: 110 SPLSP-KGRPSS-----PRTPLYLQPDAYGSLDRAT------------SPRPRAFD---- 147
+ P +G P + T L L + + T +P P +
Sbjct: 576 AKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEW 635
Query: 148 ---------GAGSSLGRAPSPRPGPGPLRQQGPPTPFDFLGRAGSPRGSPLAEGPQAFFP 198
G L PS P P + P T + ++ SP+ PQ P
Sbjct: 636 LCLNCQMKRALGGDLAPVPS---SPQPKLKTAPVTTTSAVSKS-SPQ-------PQQTSP 684
Query: 199 ERGPSPRPPATAYDAPASAFGSSLLGSGGSAFAPPLRAQDDL-----TLRRRPPKAWNES 253
++ +P+ + P PPL Q L ++PP+A +S
Sbjct: 685 KKDAAPKQDLSKAPEPKKP--------------PPLVKQPTLHGSPSAKAKQPPEA--DS 728
Query: 254 DLDVAYEKKPSQTASYERLDVFA-RPASPSLQLLPWRESSLDGLGGTGKDNLTSATLPRN 312
A K+PS + ++ V +P P +++ + T K ++ S+ +
Sbjct: 729 LSKPAPPKEPSVPSEQDKAPVADDKPKQP--KMVKPTTDLVSSSSATTKPDIPSSKVQSQ 786
Query: 313 YK---VSPLASDRRSDAGSYRRSLGSAGP--SGTLPRSWQPVSRIPMPPSSPQPRGAPRQ 367
+ PL +D + S+ + P S +PR I P S + +G +
Sbjct: 787 AEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQV 846
Query: 368 RPIPLSMIFKLQNAFWEHGASRAMLPGSPLFTRAPPPKLQPQPQPQPQP---QSQPQPQL 424
P+ + +A SP P PK P P P P+P Q+ P PQ
Sbjct: 847 DPVQK-----------KEEPKKAQTKMSPKPDAKPMPKGSPTP-PGPRPTAGQTVPTPQQ 894
Query: 425 PPQPQTQPQTPTPAPQHPQQTWPPVNEGPPKPPTELEPEPEIEGLLTPVLEAGDVDEGPV 484
P+PQ Q + + + + P PT P+ + G L
Sbjct: 895 SPKPQEQSRRFS-------LNLGSITDAPKSQPTT--PQETVTGKLFGF----GASIFSQ 941
Query: 485 ARPLSPTRLQPALPPEAQSVPELEEVARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQ 544
A L T QP P +QS P M+QAPA + PPT + +
Sbjct: 942 ASNLISTAGQPG--PHSQSGPG------------------APMKQAPAPSQPPTSQGPPK 981
Query: 545 QIISRLFHRHGGPGPGGPEPELSPITEGSEARAG----PPAPAPPA-------PIPPPAP 593
G P P + P+ + ++A A P A P PPP
Sbjct: 982 ST---------GQAPPAPAKSI-PVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIK 1031
Query: 594 SQSSPPEQPQSMEMRSVLRKAGSP 617
S +PQ + + L K+ P
Sbjct: 1032 DSKSLTAEPQKAVLPTKLEKSPKP 1055
Score = 44.7 bits (104), Expect = 4e-04
Identities = 148/697 (21%), Positives = 242/697 (34%), Gaps = 156/697 (22%)
Query: 56 PPG---PQAGP--PSRPPRYSSSSIPEPFGSRGSPRKAATDGADTPFGRSESAPTLHPYS 110
PPG P A P P++PP + S +P + P+ A P G ++ P P
Sbjct: 355 PPGTTKPPAQPLGPAKPPAQQTGS-EKPSSEQPGPKALAQ-----PPGVGKT-PAQQPGP 407
Query: 111 PLSPKGRPSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRAPSPRPGPGPL--RQ 168
P + +P+ PL QP G A +P P G+ P+ + GPG +Q
Sbjct: 408 AKPPTQQVGTPK-PLAQQP---GLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQ 463
Query: 169 QGPPTPFDFLGRAGSPRGSPLAEGPQAFFPERGPSPRPPATAYDAPASAFGSSLLGSGGS 228
GP P L G + P GP P P+ P +A P+ GS+
Sbjct: 464 TGPTKPPSQL--PGPAKPPPQQPGPAK------PPPQQPGSA-KPPSQQPGSTKPPPQQP 514
Query: 229 AFAPPLRAQDDLTLRRRPPKAWNESDLDVAYEKKPSQTASYERLDVFA-----RPASPSL 283
A P Q T +PP S A + P++ ++ + + +P P
Sbjct: 515 GPAKPSPQQPGST---KPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPT 571
Query: 284 QLLPWRESSLDGLGGT---------------GKDNLTSATLPRN-------YKVSPLASD 321
++ GL T K N + T + + +P ++
Sbjct: 572 VSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTE 631
Query: 322 RRSDAG---SYRRSLGSAGPSGTLPRSWQP-------VSRIPMPPSSPQPR-------GA 364
+ +R+LG G +P S QP + + SSPQP+ A
Sbjct: 632 VKEWLCLNCQMKRALG--GDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAA 689
Query: 365 PRQ---------RPIPLSMIFKLQNAFWEHGASRAMLPGSPLFTRAPPPKLQPQPQPQPQ 415
P+Q +P PL K A P + ++ PPK P Q +
Sbjct: 690 PKQDLSKAPEPKKPPPL---VKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDK 746
Query: 416 -PQSQPQPQLPPQPQ------------TQPQTPTPAPQH----------------PQQTW 446
P + +P+ P + T+P P+ Q P Q++
Sbjct: 747 APVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSF 806
Query: 447 PPVNE--------GPPKPPTELE------PEPEIEGL--LTPVLEAGDVDEG-------P 483
PP E P+P ++ + P E +G + PV + + + P
Sbjct: 807 PPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKP 866
Query: 484 VARPL---SPTRLQPALPPEAQSVPELEEVARVLAEIPRPLKRRGSMEQAPAVALPPTHK 540
A+P+ SPT P P Q+VP ++ + + R GS+ AP + P T +
Sbjct: 867 DAKPMPKGSPTPPGPR-PTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPK-SQPTTPQ 924
Query: 541 KQYQ--------QIISRLFHRHGGPGPGGPEPELSPITEGSEARAGPPAPAPPAPIPPPA 592
+ I S+ + G GP + P G+ + P PP PP
Sbjct: 925 ETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGP---GAPMKQAPAPSQPPTSQGPPK 981
Query: 593 PSQSSPPEQPQSMEMRSVLRKAGSPRKARRARLNPLV 629
+ +PP +S+ ++ + + + +A P V
Sbjct: 982 STGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTV 1018
Score = 44.3 bits (103), Expect = 5e-04
Identities = 67/246 (27%), Positives = 88/246 (35%), Gaps = 50/246 (20%)
Query: 356 PSSPQPRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLPGSPLFTRA-PPPKLQPQPQPQP 414
P+S P G+P +P R S L A PPP P P P P
Sbjct: 2372 PASQLPSGSPSVSSLPAK--------------PRPFFRSSSLDISAQPPPPPPPPPPPPP 2417
Query: 415 QPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPPVNEGPP--KPPTELEPEPEIEGLLTP 472
P P P LP P T P+ PT P+ PV P T LE T
Sbjct: 2418 PPPPPPPPPLP--PPTSPK-PTILPKKKLTVASPVTTATPLFDAVTTLE--------TTA 2466
Query: 473 VLEAGDVDEGPVARPLSPTRLQPALPPEAQSVPELEEVARVLAEIPRPLKRRGSMEQAPA 532
VL + + PV R T P +PP+ S+P V P P K + P
Sbjct: 2467 VLRSNGL---PVTRIC--TTAPPPVPPKPSSIPS----GLVFTHRPEPSK--PPIAPKPV 2515
Query: 533 VALPPTHKKQYQQIISRLFHRHGGPGPGGPEPELSPITEGSEARAGPPAPAPPAPIPPPA 592
+ PT ++ I P P G S +T A P+P +P+ P +
Sbjct: 2516 IPQLPTTTQKPTDI---------HPKPTGLS-LTSSMTLNLVTSADYKLPSPTSPLSPHS 2565
Query: 593 PSQSSP 598
++SSP
Sbjct: 2566 -NKSSP 2570
Score = 40.0 bits (92), Expect = 0.009
Identities = 50/201 (24%), Positives = 73/201 (36%), Gaps = 34/201 (16%)
Query: 34 TAAAKVDELTKQLESLWSDSPAPP-GPQAGPPSR--PPRYSSSSIPEPFGSRGSPRKAAT 90
+A K D + +++S + PP + PS+ PP S PF S+ PR A+
Sbjct: 771 SATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVS---PFDSKAIPRPASD 827
Query: 91 DGADTPFGRSESAPTLHPYSPLSPKGRPSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAG 150
+ G S + P+ K P +T + +PDA P P+
Sbjct: 828 SKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDA--------KPMPKG----- 874
Query: 151 SSLGRAPSPRPGPGPLRQQGPPTPFDFLGRAGSPRGSPLAEGPQAFFPERGPSPRPPATA 210
+P+P PGP P Q PTP SP+ E + F G P +
Sbjct: 875 -----SPTP-PGPRPTAGQTVPTP------QQSPKPQ---EQSRRFSLNLGSITDAPKSQ 919
Query: 211 YDAPASAFGSSLLGSGGSAFA 231
P L G G S F+
Sbjct: 920 PTTPQETVTGKLFGFGASIFS 940
Score = 36.2 bits (82), Expect = 0.13
Identities = 19/55 (34%), Positives = 24/55 (43%), Gaps = 1/55 (1%)
Query: 559 PGGPEPELSPITEGSEARAGPPAPAPPAPIPPPAPSQSSPPEQPQSMEMRSVLRK 613
P P P + A+ PP P PP P PPP P PP P + ++L K
Sbjct: 2387 PAKPRPFFRSSSLDISAQPPPPPPPPPPP-PPPPPPPPPPPLPPPTSPKPTILPK 2440
Score = 33.5 bits (75), Expect = 0.83
Identities = 36/140 (25%), Positives = 49/140 (35%), Gaps = 34/140 (24%)
Query: 339 SGTLPRSWQPVSRIPMPPSSPQPRGAPRQRPIP--------------LSMIFKLQNAFWE 384
S +L S QP P PP P P P P+P L++ + A
Sbjct: 2396 SSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPL 2455
Query: 385 HGASRAM----------LPGSPLFTRAPPPKLQPQPQP---------QPQPQSQPQPQLP 425
A + LP + + T APPP + P+P +P+P P P
Sbjct: 2456 FDAVTTLETTAVLRSNGLPVTRICTTAPPP-VPPKPSSIPSGLVFTHRPEPSKPPIAPKP 2514
Query: 426 PQPQTQPQTPTPAPQHPQQT 445
PQ T P HP+ T
Sbjct: 2515 VIPQLPTTTQKPTDIHPKPT 2534
Score = 31.6 bits (70), Expect = 3.2
Identities = 15/48 (31%), Positives = 16/48 (33%)
Query: 555 GGPGPGGPEPELSPITEGSEARAGPPAPAPPAPIPPPAPSQSSPPEQP 602
G P + P S P PP P PPP P PP P
Sbjct: 2379 GSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPP 2426
Score = 30.4 bits (67), Expect = 7.0
Identities = 43/172 (25%), Positives = 61/172 (35%), Gaps = 36/172 (20%)
Query: 54 PAPPGPQAGPPSRPPRYSSSSIPEPFGSRGSPRKAATDGADTPFGRSESAPTLHPYSPLS 113
P PP P PP PP +P P SP+ PT+ P L+
Sbjct: 2406 PPPPPPPPPPPPPPPPPPPPPLPPP----TSPK-----------------PTILPKKKLT 2444
Query: 114 PKGRPSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRAPSPRPGPGPLRQQGPPT 173
P + TPL+ DA +L+ R G + R + P P P + P+
Sbjct: 2445 -VASPVTTATPLF---DAVTTLETTAVLRSN-----GLPVTRICTTAPPPVPPKPSSIPS 2495
Query: 174 PFDFLGRAGSPRGSPLAEGPQAFFPERGPSPRPPATAYDAPASAFGSSLLGS 225
F R P P+A P+ P+ + + P + P G SL S
Sbjct: 2496 GLVFTHRP-EPSKPPIA--PKPVIPQLPTTTQKPTDIHPKPT---GLSLTSS 2541
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.132 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,803,210
Number of Sequences: 37866
Number of extensions: 3617925
Number of successful extensions: 74899
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1199
Number of HSP's successfully gapped in prelim test: 2183
Number of HSP's that attempted gapping in prelim test: 21445
Number of HSP's gapped (non-prelim): 28141
length of query: 828
length of database: 18,247,518
effective HSP length: 111
effective length of query: 717
effective length of database: 14,044,392
effective search space: 10069829064
effective search space used: 10069829064
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.