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Search of human proteins with 62632750
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|62632750 ATPase, class VI, type 11B [Homo sapiens]
(1177 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|62632750 ATPase, class VI, type 11B [Homo sapiens] 2356 0.0
gi|150421681 ATPase, class VI, type 11A isoform b [Homo sapiens] 1292 0.0
gi|150421684 ATPase, class VI, type 11A isoform a [Homo sapiens] 1292 0.0
gi|58331222 ATPase, class VI, type 11C isoform b [Homo sapiens] 1207 0.0
gi|40316839 ATPase, class VI, type 11C isoform a [Homo sapiens] 1207 0.0
gi|17978471 ATPase, aminophospholipid transporter (APLT), class ... 690 0.0
gi|157649069 ATPase, aminophospholipid transporter (APLT), class... 688 0.0
gi|117168245 ATPase, aminophospholipid transporter-like, Class I... 678 0.0
gi|50083277 ATPase class I type 8B member 4 [Homo sapiens] 660 0.0
gi|40316837 ATPase, class I, type 8B, member 2 isoform a [Homo s... 654 0.0
gi|5031697 ATPase, class I, type 8B, member 1 [Homo sapiens] 622 e-178
gi|44888835 ATPase, class I, type 8B, member 3 [Homo sapiens] 524 e-148
gi|41327760 ATPase, class II, type 9B [Homo sapiens] 459 e-129
gi|65301139 ATPase, class II, type 9A [Homo sapiens] 455 e-127
gi|222352161 ATPase, class V, type 10D [Homo sapiens] 367 e-101
gi|149944474 ATPase, class V, type 10B [Homo sapiens] 361 2e-99
gi|14424433 ATPase, class V, type 10A [Homo sapiens] 355 1e-97
gi|55743077 ATPase, class I, type 8B, member 2 isoform b [Homo s... 200 6e-51
gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sap... 94 6e-19
gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo sa... 92 4e-18
gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo sa... 92 4e-18
gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo sa... 91 6e-18
gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo sa... 91 6e-18
gi|48255951 plasma membrane calcium ATPase 2 isoform 1 [Homo sap... 89 3e-17
gi|66932949 ATPase type 13A4 [Homo sapiens] 83 1e-15
gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo sa... 82 3e-15
gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo sa... 82 3e-15
gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b [... 77 1e-13
gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a [... 77 1e-13
gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens] 70 9e-12
>gi|62632750 ATPase, class VI, type 11B [Homo sapiens]
Length = 1177
Score = 2356 bits (6105), Expect = 0.0
Identities = 1177/1177 (100%), Positives = 1177/1177 (100%)
Query: 1 MWRWIRQQLGFDPPHQSDTRTIYVANRFPQNGLYTPQKFIDNRIISSKYTVWNFVPKNLF 60
MWRWIRQQLGFDPPHQSDTRTIYVANRFPQNGLYTPQKFIDNRIISSKYTVWNFVPKNLF
Sbjct: 1 MWRWIRQQLGFDPPHQSDTRTIYVANRFPQNGLYTPQKFIDNRIISSKYTVWNFVPKNLF 60
Query: 61 EQFRRVANFYFLIIFLVQLMIDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHNSDNEVN 120
EQFRRVANFYFLIIFLVQLMIDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHNSDNEVN
Sbjct: 61 EQFRRVANFYFLIIFLVQLMIDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHNSDNEVN 120
Query: 121 GAPVYVVRSGGLVKTRSKNIRVGDIVRIAKDEIFPADLVLLSSDRLDGSCHVTTASLDGE 180
GAPVYVVRSGGLVKTRSKNIRVGDIVRIAKDEIFPADLVLLSSDRLDGSCHVTTASLDGE
Sbjct: 121 GAPVYVVRSGGLVKTRSKNIRVGDIVRIAKDEIFPADLVLLSSDRLDGSCHVTTASLDGE 180
Query: 181 TNLKTHVAVPETALLQTVANLDTLVAVIECQQPEADLYRFMGRMIITQQMEEIVRPLGPE 240
TNLKTHVAVPETALLQTVANLDTLVAVIECQQPEADLYRFMGRMIITQQMEEIVRPLGPE
Sbjct: 181 TNLKTHVAVPETALLQTVANLDTLVAVIECQQPEADLYRFMGRMIITQQMEEIVRPLGPE 240
Query: 241 SLLLRGARLKNTKEIFGVAVYTGMETKMALNYKSKSQKRSAVEKSMNTFLIIYLVILISE 300
SLLLRGARLKNTKEIFGVAVYTGMETKMALNYKSKSQKRSAVEKSMNTFLIIYLVILISE
Sbjct: 241 SLLLRGARLKNTKEIFGVAVYTGMETKMALNYKSKSQKRSAVEKSMNTFLIIYLVILISE 300
Query: 301 AVISTILKYTWQAEEKWDEPWYNQKTEHQRNSSKILRFISDFLAFLVLYNFIIPISLYVT 360
AVISTILKYTWQAEEKWDEPWYNQKTEHQRNSSKILRFISDFLAFLVLYNFIIPISLYVT
Sbjct: 301 AVISTILKYTWQAEEKWDEPWYNQKTEHQRNSSKILRFISDFLAFLVLYNFIIPISLYVT 360
Query: 361 VEMQKFLGSFFIGWDLDLYHEESDQKAQVNTSDLNEELGQVEYVFTDKTGTLTENEMQFR 420
VEMQKFLGSFFIGWDLDLYHEESDQKAQVNTSDLNEELGQVEYVFTDKTGTLTENEMQFR
Sbjct: 361 VEMQKFLGSFFIGWDLDLYHEESDQKAQVNTSDLNEELGQVEYVFTDKTGTLTENEMQFR 420
Query: 421 ECSINGMKYQEINGRLVPEGPTPDSSEGNLSYLSSLSHLNNLSHLTTSSSFRTSPENETE 480
ECSINGMKYQEINGRLVPEGPTPDSSEGNLSYLSSLSHLNNLSHLTTSSSFRTSPENETE
Sbjct: 421 ECSINGMKYQEINGRLVPEGPTPDSSEGNLSYLSSLSHLNNLSHLTTSSSFRTSPENETE 480
Query: 481 LIKEHDLFFKAVSLCHTVQISNVQTDCTGDGPWQSNLAPSQLEYYASSPDEKALVEAAAR 540
LIKEHDLFFKAVSLCHTVQISNVQTDCTGDGPWQSNLAPSQLEYYASSPDEKALVEAAAR
Sbjct: 481 LIKEHDLFFKAVSLCHTVQISNVQTDCTGDGPWQSNLAPSQLEYYASSPDEKALVEAAAR 540
Query: 541 IGIVFIGNSEETMEVKTLGKLERYKLLHILEFDSDRRRMSVIVQAPSGEKLLFAKGAESS 600
IGIVFIGNSEETMEVKTLGKLERYKLLHILEFDSDRRRMSVIVQAPSGEKLLFAKGAESS
Sbjct: 541 IGIVFIGNSEETMEVKTLGKLERYKLLHILEFDSDRRRMSVIVQAPSGEKLLFAKGAESS 600
Query: 601 ILPKCIGGEIEKTRIHVDEFALKGLRTLCIAYRKFTSKEYEEIDKRIFEARTALQQREEK 660
ILPKCIGGEIEKTRIHVDEFALKGLRTLCIAYRKFTSKEYEEIDKRIFEARTALQQREEK
Sbjct: 601 ILPKCIGGEIEKTRIHVDEFALKGLRTLCIAYRKFTSKEYEEIDKRIFEARTALQQREEK 660
Query: 661 LAAVFQFIEKDLILLGATAVEDRLQDKVRETIEALRMAGIKVWVLTGDKHETAVSVSLSC 720
LAAVFQFIEKDLILLGATAVEDRLQDKVRETIEALRMAGIKVWVLTGDKHETAVSVSLSC
Sbjct: 661 LAAVFQFIEKDLILLGATAVEDRLQDKVRETIEALRMAGIKVWVLTGDKHETAVSVSLSC 720
Query: 721 GHFHRTMNILELINQKSDSECAEQLRQLARRITEDHVIQHGLVVDGTSLSLALREHEKLF 780
GHFHRTMNILELINQKSDSECAEQLRQLARRITEDHVIQHGLVVDGTSLSLALREHEKLF
Sbjct: 721 GHFHRTMNILELINQKSDSECAEQLRQLARRITEDHVIQHGLVVDGTSLSLALREHEKLF 780
Query: 781 MEVCRNCSAVLCCRMAPLQKAKVIRLIKISPEKPITLAVGDGANDVSMIQEAHVGIGIMG 840
MEVCRNCSAVLCCRMAPLQKAKVIRLIKISPEKPITLAVGDGANDVSMIQEAHVGIGIMG
Sbjct: 781 MEVCRNCSAVLCCRMAPLQKAKVIRLIKISPEKPITLAVGDGANDVSMIQEAHVGIGIMG 840
Query: 841 KEGRQAARNSDYAIARFKFLSKLLFVHGHFYYIRIATLVQYFFYKNVCFITPQFLYQFYC 900
KEGRQAARNSDYAIARFKFLSKLLFVHGHFYYIRIATLVQYFFYKNVCFITPQFLYQFYC
Sbjct: 841 KEGRQAARNSDYAIARFKFLSKLLFVHGHFYYIRIATLVQYFFYKNVCFITPQFLYQFYC 900
Query: 901 LFSQQTLYDSVYLTLYNICFTSLPILIYSLLEQHVDPHVLQNKPTLYRDISKNRLLSIKT 960
LFSQQTLYDSVYLTLYNICFTSLPILIYSLLEQHVDPHVLQNKPTLYRDISKNRLLSIKT
Sbjct: 901 LFSQQTLYDSVYLTLYNICFTSLPILIYSLLEQHVDPHVLQNKPTLYRDISKNRLLSIKT 960
Query: 961 FLYWTILGFSHAFIFFFGSYLLIGKDTSLLGNGQMFGNWTFGTLVFTVMVITVTVKMALE 1020
FLYWTILGFSHAFIFFFGSYLLIGKDTSLLGNGQMFGNWTFGTLVFTVMVITVTVKMALE
Sbjct: 961 FLYWTILGFSHAFIFFFGSYLLIGKDTSLLGNGQMFGNWTFGTLVFTVMVITVTVKMALE 1020
Query: 1021 THFWTWINHLVTWGSIIFYFVFSLFYGGILWPFLGSQNMYFVFIQLLSSGSAWFAIILMV 1080
THFWTWINHLVTWGSIIFYFVFSLFYGGILWPFLGSQNMYFVFIQLLSSGSAWFAIILMV
Sbjct: 1021 THFWTWINHLVTWGSIIFYFVFSLFYGGILWPFLGSQNMYFVFIQLLSSGSAWFAIILMV 1080
Query: 1081 VTCLFLDIIKKVFDRHLHPTSTEKAQLTETNAGIKCLDSMCCFPEGEAACASVGRMLERV 1140
VTCLFLDIIKKVFDRHLHPTSTEKAQLTETNAGIKCLDSMCCFPEGEAACASVGRMLERV
Sbjct: 1081 VTCLFLDIIKKVFDRHLHPTSTEKAQLTETNAGIKCLDSMCCFPEGEAACASVGRMLERV 1140
Query: 1141 IGRCSPTHISRSWSASDPFYTNDRSILTLSTMDSSTC 1177
IGRCSPTHISRSWSASDPFYTNDRSILTLSTMDSSTC
Sbjct: 1141 IGRCSPTHISRSWSASDPFYTNDRSILTLSTMDSSTC 1177
>gi|150421681 ATPase, class VI, type 11A isoform b [Homo sapiens]
Length = 1191
Score = 1292 bits (3344), Expect = 0.0
Identities = 657/1119 (58%), Positives = 833/1119 (74%), Gaps = 61/1119 (5%)
Query: 18 DTRTIYVANRFPQNGL--YTPQKFIDNRIISSKYTVWNFVPKNLFEQFRRVANFYFLIIF 75
D+RTIYV +R P G Y PQ++ DNRI+SSKYT WNF+PKNLFEQFRRVANFYFLIIF
Sbjct: 22 DSRTIYVGHREPPPGAEAYIPQRYPDNRIVSSKYTFWNFIPKNLFEQFRRVANFYFLIIF 81
Query: 76 LVQLMIDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHNSDNEVNGAPVYVVRSGGLVKT 135
LVQL+IDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRH +DN +N PV+ ++ G LV+
Sbjct: 82 LVQLIIDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGKLVRK 141
Query: 136 RSKNIRVGDIVRIAKDEIFPADLVLLSSDRLDGSCHVTTASLDGETNLKTHVAVPETALL 195
+S+ +RVGDIV + +DE FP DL+ LSS+R DG+CHVTTASLDGE++ KTH AV +T
Sbjct: 142 QSRKLRVGDIVMVKEDETFPCDLIFLSSNRGDGTCHVTTASLDGESSHKTHYAVQDTKGF 201
Query: 196 QTVANLDTLVAVIECQQPEADLYRFMGRMIITQQMEE-IVRPLGPESLLLRGARLKNTKE 254
T ++ L A IEC+QP+ DLY+F+GR+ + + + +VRPLG E+LLLRGA LKNT++
Sbjct: 202 HTEEDIGGLHATIECEQPQPDLYKFVGRINVYSDLNDPVVRPLGSENLLLRGATLKNTEK 261
Query: 255 IFGVAVYTGMETKMALNYKSKSQKRSAVEKSMNTFLIIYLVILISEAVISTILKYTWQAE 314
IFGVA+YTGMETKMALNY+SKSQKRSAVEKSMN FLI+YL ILIS+A+I+T+LKY WQ+E
Sbjct: 262 IFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNAFLIVYLCILISKALINTVLKYMWQSE 321
Query: 315 EKWDEPWYNQKTEHQRNSSKILRFISDFLAFLVLYNFIIPISLYVTVEMQKFLGSFFIGW 374
DEPWYNQKTE +R + L+ +DFLAF+VL+N+IIP+S+YVTVEMQKFLGS+FI W
Sbjct: 322 PFRDEPWYNQKTESERQRNLFLKAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFITW 381
Query: 375 DLDLYHEESDQKAQVNTSDLNEELGQVEYVFTDKTGTLTENEMQFRECSINGMKYQE--- 431
D D++ EE+ + VNTSDLNEELGQVEY+FTDKTGTLTEN M+F+EC I G Y
Sbjct: 382 DEDMFDEETGEGPLVNTSDLNEELGQVEYIFTDKTGTLTENNMEFKECCIEGHVYVPHVI 441
Query: 432 INGRLVPEGPTPDSSEGNLSYLSSLSHLNNLSHLTTSSSFRTSPENETELIKEHDLFFKA 491
NG+++PE D + SS E E +LFF+A
Sbjct: 442 CNGQVLPESSGID--------------------MIDSSPSVNGRERE-------ELFFRA 474
Query: 492 VSLCHTVQISNVQTDCTGDGPWQSNLAPSQLEYYASSPDEKALVEAAARIGIVFIGNSEE 551
+ LCHTVQ+ + D + DGP +S Y +SSPDE ALVE R+G ++ +
Sbjct: 475 LCLCHTVQVKD---DDSVDGPRKSPDGGKSCVYISSSPDEVALVEGVQRLGFTYLRLKDN 531
Query: 552 TMEVKTL-GKLERYKLLHILEFDSDRRRMSVIVQAPSGEKLLFAKGAESSILPKCIGGEI 610
ME+ +ER++LL IL FDS RRRMSVIV++ +GE LF KGA+SSI P+ I G++
Sbjct: 532 YMEILNRENHIERFELLEILSFDSVRRRMSVIVKSATGEIYLFCKGADSSIFPRVIEGKV 591
Query: 611 EKTRIHVDEFALKGLRTLCIAYRKFTSKEYEEIDKRIFEARTALQQREEKLAAVFQFIEK 670
++ R V+ A++GLRTLC+AY++ +EYE I K + A+ ALQ RE+KLA ++ IEK
Sbjct: 592 DQIRARVERNAVEGLRTLCVAYKRLIQEEYEGICKLLQAAKVALQDREKKLAEAYEQIEK 651
Query: 671 DLILLGATAVEDRLQDKVRETIEALRMAGIKVWVLTGDKHETAVSVSLSCGHFHRTMNIL 730
DL LLGATAVEDRLQ+K +TIEAL+ AGIKVWVLTGDK ETA + +C F R +L
Sbjct: 652 DLTLLGATAVEDRLQEKAADTIEALQKAGIKVWVLTGDKMETAAATCYACKLFRRNTQLL 711
Query: 731 ELINQKSDS--------ECAEQLRQLARRITEDHVI-------QHGLVVDGTSLSLALRE 775
EL ++ + E ++ + + + +T D++ +GL++DG +LSL ++
Sbjct: 712 ELTTKRIEEQSLHDVLFELSKTVLRHSGSLTRDNLSGLSADMQDYGLIIDGAALSLIMKP 771
Query: 776 HE--------KLFMEVCRNCSAVLCCRMAPLQKAKVIRLIKISPEKPITLAVGDGANDVS 827
E +LF+E+CR+CSAVLCCRMAPLQKA++++LIK S E PITLA+GDGANDVS
Sbjct: 772 REDGSSGNYRELFLEICRSCSAVLCCRMAPLQKAQIVKLIKFSKEHPITLAIGDGANDVS 831
Query: 828 MIQEAHVGIGIMGKEGRQAARNSDYAIARFKFLSKLLFVHGHFYYIRIATLVQYFFYKNV 887
MI EAHVGIG++GKEGRQAARNSDYAI +FK L K+L VHGHFYYIRI+ LVQYFFYKNV
Sbjct: 832 MILEAHVGIGVIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYIRISELVQYFFYKNV 891
Query: 888 CFITPQFLYQFYCLFSQQTLYDSVYLTLYNICFTSLPILIYSLLEQHVDPHVLQNKPTLY 947
CFI PQFLYQF+C FSQQTLYD+ YLTLYNI FTSLPIL+YSL+EQHV VL+ PTLY
Sbjct: 892 CFIFPQFLYQFFCGFSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLKRDPTLY 951
Query: 948 RDISKNRLLSIKTFLYWTILGFSHAFIFFFGSYLLIGKDTSLLGNGQMFGNWTFGTLVFT 1007
RD++KN LL + F+YWT+LG A +FFFG+Y + ++T++ NGQ+FGNWTFGTLVFT
Sbjct: 952 RDVAKNALLRWRVFIYWTLLGLFDALVFFFGAYFVF-ENTTVTSNGQIFGNWTFGTLVFT 1010
Query: 1008 VMVITVTVKMALETHFWTWINHLVTWGSIIFYFVFSLFYGGILWPFLGSQNMYFVFIQLL 1067
VMV TVT+K+AL+TH+WTWINH V WGS++FY VFSL +GG++WPFL Q MY+VFIQ+L
Sbjct: 1011 VMVFTVTLKLALDTHYWTWINHFVIWGSLLFYVVFSLLWGGVIWPFLNYQRMYYVFIQML 1070
Query: 1068 SSGSAWFAIILMVVTCLFLDIIKKVFDRHLHPTSTEKAQ 1106
SSG AW AI+L+V L D++KKV R L PT+TE+ Q
Sbjct: 1071 SSGPAWLAIVLLVTISLLPDVLKKVLCRQLWPTATERVQ 1109
>gi|150421684 ATPase, class VI, type 11A isoform a [Homo sapiens]
Length = 1134
Score = 1292 bits (3344), Expect = 0.0
Identities = 657/1119 (58%), Positives = 833/1119 (74%), Gaps = 61/1119 (5%)
Query: 18 DTRTIYVANRFPQNGL--YTPQKFIDNRIISSKYTVWNFVPKNLFEQFRRVANFYFLIIF 75
D+RTIYV +R P G Y PQ++ DNRI+SSKYT WNF+PKNLFEQFRRVANFYFLIIF
Sbjct: 22 DSRTIYVGHREPPPGAEAYIPQRYPDNRIVSSKYTFWNFIPKNLFEQFRRVANFYFLIIF 81
Query: 76 LVQLMIDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHNSDNEVNGAPVYVVRSGGLVKT 135
LVQL+IDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRH +DN +N PV+ ++ G LV+
Sbjct: 82 LVQLIIDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGKLVRK 141
Query: 136 RSKNIRVGDIVRIAKDEIFPADLVLLSSDRLDGSCHVTTASLDGETNLKTHVAVPETALL 195
+S+ +RVGDIV + +DE FP DL+ LSS+R DG+CHVTTASLDGE++ KTH AV +T
Sbjct: 142 QSRKLRVGDIVMVKEDETFPCDLIFLSSNRGDGTCHVTTASLDGESSHKTHYAVQDTKGF 201
Query: 196 QTVANLDTLVAVIECQQPEADLYRFMGRMIITQQMEE-IVRPLGPESLLLRGARLKNTKE 254
T ++ L A IEC+QP+ DLY+F+GR+ + + + +VRPLG E+LLLRGA LKNT++
Sbjct: 202 HTEEDIGGLHATIECEQPQPDLYKFVGRINVYSDLNDPVVRPLGSENLLLRGATLKNTEK 261
Query: 255 IFGVAVYTGMETKMALNYKSKSQKRSAVEKSMNTFLIIYLVILISEAVISTILKYTWQAE 314
IFGVA+YTGMETKMALNY+SKSQKRSAVEKSMN FLI+YL ILIS+A+I+T+LKY WQ+E
Sbjct: 262 IFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNAFLIVYLCILISKALINTVLKYMWQSE 321
Query: 315 EKWDEPWYNQKTEHQRNSSKILRFISDFLAFLVLYNFIIPISLYVTVEMQKFLGSFFIGW 374
DEPWYNQKTE +R + L+ +DFLAF+VL+N+IIP+S+YVTVEMQKFLGS+FI W
Sbjct: 322 PFRDEPWYNQKTESERQRNLFLKAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFITW 381
Query: 375 DLDLYHEESDQKAQVNTSDLNEELGQVEYVFTDKTGTLTENEMQFRECSINGMKYQE--- 431
D D++ EE+ + VNTSDLNEELGQVEY+FTDKTGTLTEN M+F+EC I G Y
Sbjct: 382 DEDMFDEETGEGPLVNTSDLNEELGQVEYIFTDKTGTLTENNMEFKECCIEGHVYVPHVI 441
Query: 432 INGRLVPEGPTPDSSEGNLSYLSSLSHLNNLSHLTTSSSFRTSPENETELIKEHDLFFKA 491
NG+++PE D + SS E E +LFF+A
Sbjct: 442 CNGQVLPESSGID--------------------MIDSSPSVNGRERE-------ELFFRA 474
Query: 492 VSLCHTVQISNVQTDCTGDGPWQSNLAPSQLEYYASSPDEKALVEAAARIGIVFIGNSEE 551
+ LCHTVQ+ + D + DGP +S Y +SSPDE ALVE R+G ++ +
Sbjct: 475 LCLCHTVQVKD---DDSVDGPRKSPDGGKSCVYISSSPDEVALVEGVQRLGFTYLRLKDN 531
Query: 552 TMEVKTL-GKLERYKLLHILEFDSDRRRMSVIVQAPSGEKLLFAKGAESSILPKCIGGEI 610
ME+ +ER++LL IL FDS RRRMSVIV++ +GE LF KGA+SSI P+ I G++
Sbjct: 532 YMEILNRENHIERFELLEILSFDSVRRRMSVIVKSATGEIYLFCKGADSSIFPRVIEGKV 591
Query: 611 EKTRIHVDEFALKGLRTLCIAYRKFTSKEYEEIDKRIFEARTALQQREEKLAAVFQFIEK 670
++ R V+ A++GLRTLC+AY++ +EYE I K + A+ ALQ RE+KLA ++ IEK
Sbjct: 592 DQIRARVERNAVEGLRTLCVAYKRLIQEEYEGICKLLQAAKVALQDREKKLAEAYEQIEK 651
Query: 671 DLILLGATAVEDRLQDKVRETIEALRMAGIKVWVLTGDKHETAVSVSLSCGHFHRTMNIL 730
DL LLGATAVEDRLQ+K +TIEAL+ AGIKVWVLTGDK ETA + +C F R +L
Sbjct: 652 DLTLLGATAVEDRLQEKAADTIEALQKAGIKVWVLTGDKMETAAATCYACKLFRRNTQLL 711
Query: 731 ELINQKSDS--------ECAEQLRQLARRITEDHVI-------QHGLVVDGTSLSLALRE 775
EL ++ + E ++ + + + +T D++ +GL++DG +LSL ++
Sbjct: 712 ELTTKRIEEQSLHDVLFELSKTVLRHSGSLTRDNLSGLSADMQDYGLIIDGAALSLIMKP 771
Query: 776 HE--------KLFMEVCRNCSAVLCCRMAPLQKAKVIRLIKISPEKPITLAVGDGANDVS 827
E +LF+E+CR+CSAVLCCRMAPLQKA++++LIK S E PITLA+GDGANDVS
Sbjct: 772 REDGSSGNYRELFLEICRSCSAVLCCRMAPLQKAQIVKLIKFSKEHPITLAIGDGANDVS 831
Query: 828 MIQEAHVGIGIMGKEGRQAARNSDYAIARFKFLSKLLFVHGHFYYIRIATLVQYFFYKNV 887
MI EAHVGIG++GKEGRQAARNSDYAI +FK L K+L VHGHFYYIRI+ LVQYFFYKNV
Sbjct: 832 MILEAHVGIGVIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYIRISELVQYFFYKNV 891
Query: 888 CFITPQFLYQFYCLFSQQTLYDSVYLTLYNICFTSLPILIYSLLEQHVDPHVLQNKPTLY 947
CFI PQFLYQF+C FSQQTLYD+ YLTLYNI FTSLPIL+YSL+EQHV VL+ PTLY
Sbjct: 892 CFIFPQFLYQFFCGFSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLKRDPTLY 951
Query: 948 RDISKNRLLSIKTFLYWTILGFSHAFIFFFGSYLLIGKDTSLLGNGQMFGNWTFGTLVFT 1007
RD++KN LL + F+YWT+LG A +FFFG+Y + ++T++ NGQ+FGNWTFGTLVFT
Sbjct: 952 RDVAKNALLRWRVFIYWTLLGLFDALVFFFGAYFVF-ENTTVTSNGQIFGNWTFGTLVFT 1010
Query: 1008 VMVITVTVKMALETHFWTWINHLVTWGSIIFYFVFSLFYGGILWPFLGSQNMYFVFIQLL 1067
VMV TVT+K+AL+TH+WTWINH V WGS++FY VFSL +GG++WPFL Q MY+VFIQ+L
Sbjct: 1011 VMVFTVTLKLALDTHYWTWINHFVIWGSLLFYVVFSLLWGGVIWPFLNYQRMYYVFIQML 1070
Query: 1068 SSGSAWFAIILMVVTCLFLDIIKKVFDRHLHPTSTEKAQ 1106
SSG AW AI+L+V L D++KKV R L PT+TE+ Q
Sbjct: 1071 SSGPAWLAIVLLVTISLLPDVLKKVLCRQLWPTATERVQ 1109
>gi|58331222 ATPase, class VI, type 11C isoform b [Homo sapiens]
Length = 1119
Score = 1207 bits (3124), Expect = 0.0
Identities = 611/1105 (55%), Positives = 788/1105 (71%), Gaps = 74/1105 (6%)
Query: 19 TRTIYVANR-FPQNGLYTPQKFIDNRIISSKYTVWNFVPKNLFEQFRRVANFYFLIIFLV 77
TRT++V N + Y Q+F DNRI+SSKYT+WNF+PKNLFEQFRR+ANFYFLIIFLV
Sbjct: 22 TRTVFVGNHPVSETEAYIAQRFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLV 81
Query: 78 QLMIDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHNSDNEVNGAPVYVVRSGGLVKTRS 137
Q+ +DTPTSPVTSGLPLFFVITVTAIKQGYEDWLRH +DNEVN + VY++ + V+ S
Sbjct: 82 QVTVDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHRADNEVNKSTVYIIENAKRVRKES 141
Query: 138 KNIRVGDIVRIAKDEIFPADLVLLSSDRLDGSCHVTTASLDGETNLKTHVAVPETALLQT 197
+ I+VGD+V + DE FP DL+LLSS DG+C+VTTASLDGE+N KTH AV +T L T
Sbjct: 142 EKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIALCT 201
Query: 198 VANLDTLVAVIECQQPEADLYRFMGRM-IITQQMEEIVRPLGPESLLLRGARLKNTKEIF 256
++DTL A IEC+QP+ DLY+F+GR+ I + +E + R LGPE+LLL+GA LKNT++I+
Sbjct: 202 AESIDTLRAAIECEQPQPDLYKFVGRINIYSNSLEAVARSLGPENLLLKGATLKNTEKIY 261
Query: 257 GVAVYTGMETKMALNYKSKSQKRSAVEKSMNTFLIIYLVILISEAVISTILKYTWQAEEK 316
GVAVYTGMETKMALNY+ KSQKRSAVEKS+N FLI+YL IL+++A + T LKY WQ+
Sbjct: 262 GVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLFILLTKAAVCTTLKYVWQSTPY 321
Query: 317 WDEPWYNQKTEHQRNSSKILRFISDFLAFLVLYNFIIPISLYVTVEMQKFLGSFFIGWDL 376
DEPWYNQKT+ +R + K+L+ +DFL+F+VL+NFIIP+S+YVTVEMQKFLGSFFI WD
Sbjct: 322 NDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFISWDK 381
Query: 377 DLYHEESDQKAQVNTSDLNEELGQVEYVFTDKTGTLTENEMQFRECSINGMKY----QEI 432
D Y EE ++ A VNTSDLNEELGQV+YVFTDKTGTLTEN M+F EC I+G KY QE+
Sbjct: 382 DFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKYKGVTQEV 441
Query: 433 NGRLVPEGPTPDSSEGNLSYLSSLSHLNNLSHLTTSSSFRTSPENETELIKEHDLFFKAV 492
+G ++G L+Y + +LF +A+
Sbjct: 442 DGL--------SQTDGTLTYFDKVDK------------------------NREELFLRAL 469
Query: 493 SLCHTVQISNVQTDCTGDGPWQSNLAPSQLEYYASSPDEKALVEAAARIGIVFIGNSEET 552
LCHTV+I +T+ DG +S ++L Y +SSPDE ALV+ A R G F+GN
Sbjct: 470 CLCHTVEI---KTNDAVDGATES----AELTYISSSPDEIALVKGAKRYGFTFLGNRNGY 522
Query: 553 MEVKTLGK-LERYKLLHILEFDSDRRRMSVIVQAPSGEKLLFAKGAESSILPKCIGGEIE 611
M V+ K +E Y+LLH L FD+ RRRMSVIV+ G+ LLF KGA+S++ P+ EIE
Sbjct: 523 MRVENQRKEIEEYELLHTLNFDAVRRRMSVIVKTQEGDILLFCKGADSAVFPRVQNHEIE 582
Query: 612 KTRIHVDEFALKGLRTLCIAYRKFTSKEYEEIDKRIFEARTALQQREEKLAAVFQFIEKD 671
T++HV+ A+ G RTLC+A+++ +YE I++++ EA+ ALQ REEK+ VF IE +
Sbjct: 583 LTKVHVERNAMDGYRTLCVAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETN 642
Query: 672 LILLGATAVEDRLQDKVRETIEALRMAGIKVWVLTGDKHETAVSVSLSCGHFHRTMNILE 731
+ L+GATAVED+LQD+ ETIEAL AG+KVWVLTGDK ETA S +C F +LE
Sbjct: 643 MNLIGATAVEDKLQDQAAETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLE 702
Query: 732 LI------NQKSDSECAEQLRQLARRITED-------------HVIQHGLVVDGTSLSLA 772
L +++ + E L + +++ + ++GL++DG++LSL
Sbjct: 703 LTTKTIEESERKEDRLHELLIEYRKKLLHEFPKSTRSFKKAWTEHQEYGLIIDGSTLSLI 762
Query: 773 L--------REHEKLFMEVCRNCSAVLCCRMAPLQKAKVIRLIKISPEKPITLAVGDGAN 824
L ++ +F+++C C+AVLCCRMAPLQKA+++R++K PITL++GDGAN
Sbjct: 763 LNSSQDSSSNNYKSIFLQICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGAN 822
Query: 825 DVSMIQEAHVGIGIMGKEGRQAARNSDYAIARFKFLSKLLFVHGHFYYIRIATLVQYFFY 884
DVSMI E+HVGIGI GKEGRQAARNSDY++ +FK L KLL HGH YY+RIA LVQYFFY
Sbjct: 823 DVSMILESHVGIGIKGKEGRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFY 882
Query: 885 KNVCFITPQFLYQFYCLFSQQTLYDSVYLTLYNICFTSLPILIYSLLEQHVDPHVLQNKP 944
KN+CFI PQFLYQF+C FSQQ LYD+ YLT+YNICFTSLPIL YSLLEQH++ L + P
Sbjct: 883 KNLCFILPQFLYQFFCGFSQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDP 942
Query: 945 TLYRDISKNRLLSIKTFLYWTILGFSHAFIFFFGSYLLIGKDTSLLGNGQMFGNWTFGTL 1004
LY IS N +L + FLYWT L +FFFG+Y L + SL NG+++GNWTFGT+
Sbjct: 943 RLYMKISGNAMLQLGPFLYWTFLAAFEGTVFFFGTYFLF-QTASLEENGKVYGNWTFGTI 1001
Query: 1005 VFTVMVITVTVKMALETHFWTWINHLVTWGSIIFYFVFSLFYGGILWPFLGSQNMYFVFI 1064
VFTV+V TVT+K+AL+T FWTWINH V WGS+ FY FS F+GGI+WPFL Q MYFVF
Sbjct: 1002 VFTVLVFTVTLKLALDTRFWTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQQRMYFVFA 1061
Query: 1065 QLLSSGSAWFAIILMVVTCLFLDII 1089
Q+LSS S W AIIL++ LF +I+
Sbjct: 1062 QMLSSVSTWLAIILLIFISLFPEIL 1086
>gi|40316839 ATPase, class VI, type 11C isoform a [Homo sapiens]
Length = 1132
Score = 1207 bits (3124), Expect = 0.0
Identities = 611/1105 (55%), Positives = 788/1105 (71%), Gaps = 74/1105 (6%)
Query: 19 TRTIYVANR-FPQNGLYTPQKFIDNRIISSKYTVWNFVPKNLFEQFRRVANFYFLIIFLV 77
TRT++V N + Y Q+F DNRI+SSKYT+WNF+PKNLFEQFRR+ANFYFLIIFLV
Sbjct: 22 TRTVFVGNHPVSETEAYIAQRFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLV 81
Query: 78 QLMIDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHNSDNEVNGAPVYVVRSGGLVKTRS 137
Q+ +DTPTSPVTSGLPLFFVITVTAIKQGYEDWLRH +DNEVN + VY++ + V+ S
Sbjct: 82 QVTVDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHRADNEVNKSTVYIIENAKRVRKES 141
Query: 138 KNIRVGDIVRIAKDEIFPADLVLLSSDRLDGSCHVTTASLDGETNLKTHVAVPETALLQT 197
+ I+VGD+V + DE FP DL+LLSS DG+C+VTTASLDGE+N KTH AV +T L T
Sbjct: 142 EKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIALCT 201
Query: 198 VANLDTLVAVIECQQPEADLYRFMGRM-IITQQMEEIVRPLGPESLLLRGARLKNTKEIF 256
++DTL A IEC+QP+ DLY+F+GR+ I + +E + R LGPE+LLL+GA LKNT++I+
Sbjct: 202 AESIDTLRAAIECEQPQPDLYKFVGRINIYSNSLEAVARSLGPENLLLKGATLKNTEKIY 261
Query: 257 GVAVYTGMETKMALNYKSKSQKRSAVEKSMNTFLIIYLVILISEAVISTILKYTWQAEEK 316
GVAVYTGMETKMALNY+ KSQKRSAVEKS+N FLI+YL IL+++A + T LKY WQ+
Sbjct: 262 GVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLFILLTKAAVCTTLKYVWQSTPY 321
Query: 317 WDEPWYNQKTEHQRNSSKILRFISDFLAFLVLYNFIIPISLYVTVEMQKFLGSFFIGWDL 376
DEPWYNQKT+ +R + K+L+ +DFL+F+VL+NFIIP+S+YVTVEMQKFLGSFFI WD
Sbjct: 322 NDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFISWDK 381
Query: 377 DLYHEESDQKAQVNTSDLNEELGQVEYVFTDKTGTLTENEMQFRECSINGMKY----QEI 432
D Y EE ++ A VNTSDLNEELGQV+YVFTDKTGTLTEN M+F EC I+G KY QE+
Sbjct: 382 DFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKYKGVTQEV 441
Query: 433 NGRLVPEGPTPDSSEGNLSYLSSLSHLNNLSHLTTSSSFRTSPENETELIKEHDLFFKAV 492
+G ++G L+Y + +LF +A+
Sbjct: 442 DGL--------SQTDGTLTYFDKVDK------------------------NREELFLRAL 469
Query: 493 SLCHTVQISNVQTDCTGDGPWQSNLAPSQLEYYASSPDEKALVEAAARIGIVFIGNSEET 552
LCHTV+I +T+ DG +S ++L Y +SSPDE ALV+ A R G F+GN
Sbjct: 470 CLCHTVEI---KTNDAVDGATES----AELTYISSSPDEIALVKGAKRYGFTFLGNRNGY 522
Query: 553 MEVKTLGK-LERYKLLHILEFDSDRRRMSVIVQAPSGEKLLFAKGAESSILPKCIGGEIE 611
M V+ K +E Y+LLH L FD+ RRRMSVIV+ G+ LLF KGA+S++ P+ EIE
Sbjct: 523 MRVENQRKEIEEYELLHTLNFDAVRRRMSVIVKTQEGDILLFCKGADSAVFPRVQNHEIE 582
Query: 612 KTRIHVDEFALKGLRTLCIAYRKFTSKEYEEIDKRIFEARTALQQREEKLAAVFQFIEKD 671
T++HV+ A+ G RTLC+A+++ +YE I++++ EA+ ALQ REEK+ VF IE +
Sbjct: 583 LTKVHVERNAMDGYRTLCVAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETN 642
Query: 672 LILLGATAVEDRLQDKVRETIEALRMAGIKVWVLTGDKHETAVSVSLSCGHFHRTMNILE 731
+ L+GATAVED+LQD+ ETIEAL AG+KVWVLTGDK ETA S +C F +LE
Sbjct: 643 MNLIGATAVEDKLQDQAAETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLE 702
Query: 732 LI------NQKSDSECAEQLRQLARRITED-------------HVIQHGLVVDGTSLSLA 772
L +++ + E L + +++ + ++GL++DG++LSL
Sbjct: 703 LTTKTIEESERKEDRLHELLIEYRKKLLHEFPKSTRSFKKAWTEHQEYGLIIDGSTLSLI 762
Query: 773 L--------REHEKLFMEVCRNCSAVLCCRMAPLQKAKVIRLIKISPEKPITLAVGDGAN 824
L ++ +F+++C C+AVLCCRMAPLQKA+++R++K PITL++GDGAN
Sbjct: 763 LNSSQDSSSNNYKSIFLQICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGAN 822
Query: 825 DVSMIQEAHVGIGIMGKEGRQAARNSDYAIARFKFLSKLLFVHGHFYYIRIATLVQYFFY 884
DVSMI E+HVGIGI GKEGRQAARNSDY++ +FK L KLL HGH YY+RIA LVQYFFY
Sbjct: 823 DVSMILESHVGIGIKGKEGRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFY 882
Query: 885 KNVCFITPQFLYQFYCLFSQQTLYDSVYLTLYNICFTSLPILIYSLLEQHVDPHVLQNKP 944
KN+CFI PQFLYQF+C FSQQ LYD+ YLT+YNICFTSLPIL YSLLEQH++ L + P
Sbjct: 883 KNLCFILPQFLYQFFCGFSQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDP 942
Query: 945 TLYRDISKNRLLSIKTFLYWTILGFSHAFIFFFGSYLLIGKDTSLLGNGQMFGNWTFGTL 1004
LY IS N +L + FLYWT L +FFFG+Y L + SL NG+++GNWTFGT+
Sbjct: 943 RLYMKISGNAMLQLGPFLYWTFLAAFEGTVFFFGTYFLF-QTASLEENGKVYGNWTFGTI 1001
Query: 1005 VFTVMVITVTVKMALETHFWTWINHLVTWGSIIFYFVFSLFYGGILWPFLGSQNMYFVFI 1064
VFTV+V TVT+K+AL+T FWTWINH V WGS+ FY FS F+GGI+WPFL Q MYFVF
Sbjct: 1002 VFTVLVFTVTLKLALDTRFWTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQQRMYFVFA 1061
Query: 1065 QLLSSGSAWFAIILMVVTCLFLDII 1089
Q+LSS S W AIIL++ LF +I+
Sbjct: 1062 QMLSSVSTWLAIILLIFISLFPEIL 1086
>gi|17978471 ATPase, aminophospholipid transporter (APLT), class I,
type 8A, member 1 isoform a [Homo sapiens]
Length = 1164
Score = 690 bits (1781), Expect = 0.0
Identities = 423/1118 (37%), Positives = 638/1118 (57%), Gaps = 80/1118 (7%)
Query: 16 QSDTRTIYVANRFPQNGLYTPQ--KFIDNRIISSKYTVWNFVPKNLFEQFRRVANFYFLI 73
Q + RTI++ PQ KF +N + ++KY + F+P+ L+ QFRR AN +FL
Sbjct: 33 QEEVRTIFINQ---------PQLTKFCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLF 83
Query: 74 IFLVQLMID-TPTSPVTSGLPLFFVITVTAIKQGYEDWLRHNSDNEVNGAPVYVVRSGGL 132
I L+Q + D +PT T+ +PL F++ V AIK+ ED RH +DN VN V+R+G
Sbjct: 84 IALLQQIPDVSPTGRYTTLVPLLFILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAW 143
Query: 133 VKTRSKNIRVGDIVRIAKDEIFPADLVLLSSDRLDGSCHVTTASLDGETNLKTHVAVPET 192
+ + VG+IV++ E PADL+ LSS C++ T++LDGETNLK +P T
Sbjct: 144 EIVHWEKVAVGEIVKVTNGEHLPADLISLSSSEPQAMCYIETSNLDGETNLKIRQGLPAT 203
Query: 193 ALLQTVANLDTLVAVIECQQPEADLYRFMGRMIITQQMEEIVRPLGPESLLLRGARLKNT 252
+ ++ V +L + IEC+ P LY F+G + + PLG + +LLRGA+L+NT
Sbjct: 204 SDIKDVDSLMRISGRIECESPNRHLYDFVGNIRLDGHGTV---PLGADQILLRGAQLRNT 260
Query: 253 KEIFGVAVYTGMETKMALNYKSKSQKRSAVEKSMNTFLIIYLVILISEAVISTILKYTWQ 312
+ + G+ VYTG +TK+ N S K S VE+ N ++I ILI+ +++ ++ W
Sbjct: 261 QWVHGIVVYTGHDTKLMQNSTSPPLKLSNVERITNVQILILFCILIAMSLVCSVGSAIWN 320
Query: 313 AEEKWDEPWYNQKTEHQRNSSKILRFISDFLAFLVLYNFIIPISLYVTVEMQKFLGSFFI 372
+ WY N F +FL F++L+N +IPISL VT+E+ KF ++FI
Sbjct: 321 RRHSGKD-WYLNL-----NYGGASNFGLNFLTFIILFNNLIPISLLVTLEVVKFTQAYFI 374
Query: 373 GWDLDLYHEESDQKAQVNTSDLNEELGQVEYVFTDKTGTLTENEMQFRECSINGMKYQEI 432
WDLD+++E +D A TS+LNEELGQV+Y+F+DKTGTLT N MQF++C+I G+ Y
Sbjct: 375 NWDLDMHYEPTDTAAMARTSNLNEELGQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGH- 433
Query: 433 NGRLVPE----GPTPD----SSEGNLSYLSSLSHLNNLSHLTTSSSFRTSPENETELIKE 484
VPE G +PD S G+ S S L NL + + T+P +I E
Sbjct: 434 ----VPEPEDYGCSPDEWQNSQFGDEKTFSDSSLLENLQN-----NHPTAP-----IICE 479
Query: 485 HDLFFKAVSLCHTVQISNVQTDCTGDGPWQSNLAPSQLEYYASSPDEKALVEAAARIGIV 544
F +++CHT + GD ++ Y A+SPDE ALV AA ++ V
Sbjct: 480 ---FLTMMAVCHTAV-----PEREGD----------KIIYQAASPDEGALVRAAKQLNFV 521
Query: 545 FIGNSEETMEVKTLGKLERYKLLHILEFDSDRRRMSVIVQAPSGEKLLFAKGAESSILPK 604
F G + +++ + +LG+ ERY+LL++LEF S R+RMSVIV+ PSG+ L+ KGA++ I +
Sbjct: 522 FTGRTPDSVIIDSLGQEERYELLNVLEFTSARKRMSVIVRTPSGKLRLYCKGADTVIYDR 581
Query: 605 CIGGEIEK--TRIHVDEFALKGLRTLCIAYRKFTSKEYEEIDKRIFEARTALQQREEKLA 662
K T H+++FA +GLRTLC A + + +++E A T++Q R KL
Sbjct: 582 LAETSKYKEITLKHLEQFATEGLRTLCFAVAEISESDFQEWRAVYQRASTSVQNRLLKLE 641
Query: 663 AVFQFIEKDLILLGATAVEDRLQDKVRETIEALRMAGIKVWVLTGDKHETAVSVSLSCGH 722
++ IEK+L LLGATA+ED+LQD+V ETIE L A IK+W+LTGDK ETA+++ SC
Sbjct: 642 ESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIKIWILTGDKQETAINIGHSCKL 701
Query: 723 FHRTMNILELINQKSDSECAEQLRQ----LARRITEDHVIQHGLVVDGTSLSLALREH-E 777
+ M ++ +IN+ S E L + L + +++ L++DG +L AL
Sbjct: 702 LKKNMGMI-VINEGSLDGTRETLSRHCTTLGDALRKEN--DFALIIDGKTLKYALTFGVR 758
Query: 778 KLFMEVCRNCSAVLCCRMAPLQKAKVIRLIKISPEKPITLAVGDGANDVSMIQEAHVGIG 837
+ F+++ +C AV+CCR++PLQK++V+ ++K K +TLA+GDGANDVSMIQ AHVG+G
Sbjct: 759 QYFLDLALSCKAVICCRVSPLQKSEVVEMVK-KQVKVVTLAIGDGANDVSMIQTAHVGVG 817
Query: 838 IMGKEGRQAARNSDYAIARFKFLSKLLFVHGHFYYIRIATLVQYFFYKNVCFITPQFLYQ 897
I G EG QAA +SDY+IA+FK+L LL +HG + Y R++ + Y FYKN+ + +
Sbjct: 818 ISGNEGLQAANSSDYSIAQFKYLKNLLMIHGAWNYNRVSKCILYCFYKNIVLYIIEIWFA 877
Query: 898 FYCLFSQQTLYDSVYLTLYNICFTSLPILIYSLLEQHVDPHVLQNKPTLYRDISKNRLLS 957
F FS Q L++ + LYN+ FT++P L + E+ + P LY+ + L
Sbjct: 878 FVNGFSGQILFERWCIGLYNVMFTAMPPLTLGIFERSCRKENMLKYPELYK--TSQNALD 935
Query: 958 IKTFLYWT--ILGFSHAFIFFFGSYLLIGKDTSLLGNGQMFGNWTFGTLVFTVMVITVTV 1015
T ++W + G H+ I F+ + T+ GNG+ G V+T +VITV +
Sbjct: 936 FNTKVFWVHCLNGLFHSVILFWFPLKALQYGTA-FGNGKTSDYLLLGNFVYTFVVITVCL 994
Query: 1016 KMALETHFWTWINHLVTWGSIIFYFVFSLFYGGILWPFLG-SQNMYFVFIQLLSSGSAWF 1074
K LET +WTW +H+ WGSI + VF Y LWP + + +M L SSG W
Sbjct: 995 KAGLETSYWTWFSHIAIWGSIALWVVFFGIYSS-LWPAIPMAPDMSGEAAMLFSSGVFWM 1053
Query: 1075 AIILMVVTCLFLDIIKKVFDRHLHPTSTEKAQLTETNA 1112
++ + V L LD++ KV R T ++ Q E +
Sbjct: 1054 GLLFIPVASLLLDVVYKVIKRTAFKTLVDEVQELEAKS 1091
>gi|157649069 ATPase, aminophospholipid transporter (APLT), class I,
type 8A, member 1 isoform b [Homo sapiens]
Length = 1149
Score = 688 bits (1776), Expect = 0.0
Identities = 420/1110 (37%), Positives = 632/1110 (56%), Gaps = 79/1110 (7%)
Query: 16 QSDTRTIYVANRFPQNGLYTPQ--KFIDNRIISSKYTVWNFVPKNLFEQFRRVANFYFLI 73
Q + RTI++ PQ KF +N + ++KY + F+P+ L+ QFRR AN +FL
Sbjct: 33 QEEVRTIFINQ---------PQLTKFCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLF 83
Query: 74 IFLVQLMID-TPTSPVTSGLPLFFVITVTAIKQGYEDWLRHNSDNEVNGAPVYVVRSGGL 132
I L+Q + D +PT T+ +PL F++ V AIK+ ED RH +DN VN V+R+G
Sbjct: 84 IALLQQIPDVSPTGRYTTLVPLLFILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAW 143
Query: 133 VKTRSKNIRVGDIVRIAKDEIFPADLVLLSSDRLDGSCHVTTASLDGETNLKTHVAVPET 192
+ + VGDIV I E PAD VLLSS C++ T++LDGETNLK +P T
Sbjct: 144 EIVHWEKVNVGDIVIIKGKEYIPADTVLLSSSEPQAMCYIETSNLDGETNLKIRQGLPAT 203
Query: 193 ALLQTVANLDTLVAVIECQQPEADLYRFMGRMIITQQMEEIVRPLGPESLLLRGARLKNT 252
+ ++ V +L + IEC+ P LY F+G + + PLG + +LLRGA+L+NT
Sbjct: 204 SDIKDVDSLMRISGRIECESPNRHLYDFVGNIRLDGHGTV---PLGADQILLRGAQLRNT 260
Query: 253 KEIFGVAVYTGMETKMALNYKSKSQKRSAVEKSMNTFLIIYLVILISEAVISTILKYTWQ 312
+ + G+ VYTG +TK+ N S K S VE+ N ++I ILI+ +++ ++ W
Sbjct: 261 QWVHGIVVYTGHDTKLMQNSTSPPLKLSNVERITNVQILILFCILIAMSLVCSVGSAIWN 320
Query: 313 AEEKWDEPWYNQKTEHQRNSSKILRFISDFLAFLVLYNFIIPISLYVTVEMQKFLGSFFI 372
+ WY N F +FL F++L+N +IPISL VT+E+ KF ++FI
Sbjct: 321 RRHSGKD-WYLNL-----NYGGASNFGLNFLTFIILFNNLIPISLLVTLEVVKFTQAYFI 374
Query: 373 GWDLDLYHEESDQKAQVNTSDLNEELGQVEYVFTDKTGTLTENEMQFRECSINGMKYQEI 432
WDLD+++E +D A TS+LNEELGQV+Y+F+DKTGTLT N MQF++C+I G+ Y +
Sbjct: 375 NWDLDMHYEPTDTAAMARTSNLNEELGQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGQ- 433
Query: 433 NGRLVPEGPTPDSSEGNLSYLSSLSHLNNLSHLTTSSSFRTSPENETELIKEHDLFFKAV 492
+S G+ S S L NL + + T+P +I E F +
Sbjct: 434 -----------NSQFGDEKTFSDSSLLENLQN-----NHPTAP-----IICE---FLTMM 469
Query: 493 SLCHTVQISNVQTDCTGDGPWQSNLAPSQLEYYASSPDEKALVEAAARIGIVFIGNSEET 552
++CHT + GD ++ Y A+SPDE ALV AA ++ VF G + ++
Sbjct: 470 AVCHTAV-----PEREGD----------KIIYQAASPDEGALVRAAKQLNFVFTGRTPDS 514
Query: 553 MEVKTLGKLERYKLLHILEFDSDRRRMSVIVQAPSGEKLLFAKGAESSILPKCIGGEIEK 612
+ + +LG+ ERY+LL++LEF S R+RMSVIV+ PSG+ L+ KGA++ I + K
Sbjct: 515 VIIDSLGQEERYELLNVLEFTSARKRMSVIVRTPSGKLRLYCKGADTVIYDRLAETSKYK 574
Query: 613 --TRIHVDEFALKGLRTLCIAYRKFTSKEYEEIDKRIFEARTALQQREEKLAAVFQFIEK 670
T H+++FA +GLRTLC A + + +++E A T++Q R KL ++ IEK
Sbjct: 575 EITLKHLEQFATEGLRTLCFAVAEISESDFQEWRAVYQRASTSVQNRLLKLEESYELIEK 634
Query: 671 DLILLGATAVEDRLQDKVRETIEALRMAGIKVWVLTGDKHETAVSVSLSCGHFHRTMNIL 730
+L LLGATA+ED+LQD+V ETIE L A IK+W+LTGDK ETA+++ SC + M ++
Sbjct: 635 NLQLLGATAIEDKLQDQVPETIETLMKADIKIWILTGDKQETAINIGHSCKLLKKNMGMI 694
Query: 731 ELINQKSDSECAEQLRQ----LARRITEDHVIQHGLVVDGTSLSLALREH-EKLFMEVCR 785
+IN+ S E L + L + +++ L++DG +L AL + F+++
Sbjct: 695 -VINEGSLDGTRETLSRHCTTLGDALRKEN--DFALIIDGKTLKYALTFGVRQYFLDLAL 751
Query: 786 NCSAVLCCRMAPLQKAKVIRLIKISPEKPITLAVGDGANDVSMIQEAHVGIGIMGKEGRQ 845
+C AV+CCR++PLQK++V+ ++K K +TLA+GDGANDVSMIQ AHVG+GI G EG Q
Sbjct: 752 SCKAVICCRVSPLQKSEVVEMVK-KQVKVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQ 810
Query: 846 AARNSDYAIARFKFLSKLLFVHGHFYYIRIATLVQYFFYKNVCFITPQFLYQFYCLFSQQ 905
AA +SDY+IA+FK+L LL +HG + Y R++ + Y FYKN+ + + F FS Q
Sbjct: 811 AANSSDYSIAQFKYLKNLLMIHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQ 870
Query: 906 TLYDSVYLTLYNICFTSLPILIYSLLEQHVDPHVLQNKPTLYRDISKNRLLSIKTFLYWT 965
L++ + LYN+ FT++P L + E+ + P LY+ + L T ++W
Sbjct: 871 ILFERWCIGLYNVMFTAMPPLTLGIFERSCRKENMLKYPELYK--TSQNALDFNTKVFWV 928
Query: 966 --ILGFSHAFIFFFGSYLLIGKDTSLLGNGQMFGNWTFGTLVFTVMVITVTVKMALETHF 1023
+ G H+ I F+ + T+ GNG+ G V+T +VITV +K LET +
Sbjct: 929 HCLNGLFHSVILFWFPLKALQYGTA-FGNGKTSDYLLLGNFVYTFVVITVCLKAGLETSY 987
Query: 1024 WTWINHLVTWGSIIFYFVFSLFYGGILWPFLG-SQNMYFVFIQLLSSGSAWFAIILMVVT 1082
WTW +H+ WGSI + VF Y LWP + + +M L SSG W ++ + V
Sbjct: 988 WTWFSHIAIWGSIALWVVFFGIYSS-LWPAIPMAPDMSGEAAMLFSSGVFWMGLLFIPVA 1046
Query: 1083 CLFLDIIKKVFDRHLHPTSTEKAQLTETNA 1112
L LD++ KV R T ++ Q E +
Sbjct: 1047 SLLLDVVYKVIKRTAFKTLVDEVQELEAKS 1076
>gi|117168245 ATPase, aminophospholipid transporter-like, Class I,
type 8A, member 2 [Homo sapiens]
Length = 1188
Score = 678 bits (1750), Expect = 0.0
Identities = 420/1124 (37%), Positives = 620/1124 (55%), Gaps = 52/1124 (4%)
Query: 5 IRQQLGFDPPHQSDTRTIYVANRF--PQNGLYTPQ----KFIDNRIISSKYTVWNFVPKN 58
+R LG+ +R V ++ P +Y Q KF DN+I ++KY+V F+P+
Sbjct: 28 VRSSLGYKKAEDEMSRATSVGDQLEAPARTIYLNQPHLNKFRDNQISTAKYSVLTFLPRF 87
Query: 59 LFEQFRRVANFYFLIIFLVQLMID-TPTSPVTSGLPLFFVITVTAIKQGYEDWLRHNSDN 117
L+EQ RR AN +FL I L+Q + D +PT T+ +PL ++T+ IK+ ED+ RH +DN
Sbjct: 88 LYEQIRRAANAFFLFIALLQQIPDVSPTGRYTTLVPLIIILTIAGIKEIVEDFKRHKADN 147
Query: 118 EVNGAPVYVVRSGGLVKTRSKNIRVGDIVRIAKDEIFPADLVLLSSDRLDGSCHVTTASL 177
VN V+R+G K + VGDIV++ + PAD+VLLSS C+V TA+L
Sbjct: 148 AVNKKKTIVLRNGMWHTIMWKEVAVGDIVKVVNGQYLPADVVLLSSSEPQAMCYVETANL 207
Query: 178 DGETNLKTHVAVPETALLQTVANLDTLVAVIECQQPEADLYRFMGRMIITQQMEEIVRPL 237
DGETNLK + TA +QT L L IEC+ P LY F G + + + + L
Sbjct: 208 DGETNLKIRQGLSHTADMQTREVLMKLSGTIECEGPNRHLYDFTGNLNLDGKS---LVAL 264
Query: 238 GPESLLLRGARLKNTKEIFGVAVYTGMETKMALNYKSKSQKRSAVEKSMNTFLIIYLVIL 297
GP+ +LLRG +L+NT+ +FG+ VYTG +TK+ N KRS VEK N +++ IL
Sbjct: 265 GPDQILLRGTQLRNTQWVFGIVVYTGHDTKLMQNSTKAPLKRSNVEKVTNVQILVLFGIL 324
Query: 298 ISEAVISTILKYTWQAEEKWDEPWYNQKTEHQRNSSKILRFISDFLAFLVLYNFIIPISL 357
+ A++S+ W ++ WY +K + ++ F + L F++LYN +IPISL
Sbjct: 325 LVMALVSSAGALYWNRSHG-EKNWYIKKMDTTSDN-----FGYNLLTFIILYNNLIPISL 378
Query: 358 YVTVEMQKFLGSFFIGWDLDLYHEESDQKAQVNTSDLNEELGQVEYVFTDKTGTLTENEM 417
VT+E+ K+ + FI WD D+Y+ +D A TS+LNEELGQV+Y+F+DKTGTLT N M
Sbjct: 379 LVTLEVVKYTQALFINWDTDMYYIGNDTPAMARTSNLNEELGQVKYLFSDKTGTLTCNIM 438
Query: 418 QFRECSINGMKYQEINGRLVPEGPTPDSSEGNLSYLSSLSHLNNLSHLTTSSSFRTSPEN 477
F++CSI G+ Y L E + D S + T+P
Sbjct: 439 NFKKCSIAGVTYGHFP-ELAREPSSDDFCRMPPPCSDSCDFDDPRLLKNIEDRHPTAP-- 495
Query: 478 ETELIKEHDLFFKAVSLCHTVQISNVQTDCTGDGPWQSNLAPSQLEYYASSPDEKALVEA 537
I+E F +++CHTV DG + Y ASSPDE ALV+
Sbjct: 496 ---CIQE---FLTLLAVCHTVVPEK-------DG--------DNIIYQASSPDEAALVKG 534
Query: 538 AARIGIVFIGNSEETMEVKTLGKLERYKLLHILEFDSDRRRMSVIVQAPSGEKLLFAKGA 597
A ++G VF + ++ ++ +G+ + + +L++LEF SDR+RMSVIV+ PSG L+ KGA
Sbjct: 535 AKKLGFVFTARTPFSVIIEAMGQEQTFGILNVLEFSSDRKRMSVIVRTPSGRLRLYCKGA 594
Query: 598 ESSILPKCIGGE--IEKTRIHVDEFALKGLRTLCIAYRKFTSKEYEEIDKRIFEARTALQ 655
++ I + +E+T H++ FA +GLRTLC+AY + EYEE K EA T L+
Sbjct: 595 DNVIFERLSKDSKYMEETLCHLEYFATEGLRTLCVAYADLSENEYEEWLKVYQEASTILK 654
Query: 656 QREEKLAAVFQFIEKDLILLGATAVEDRLQDKVRETIEALRMAGIKVWVLTGDKHETAVS 715
R ++L ++ IEK+L+LLGATA+EDRLQ V ETI L A IK+WVLTGDK ETA++
Sbjct: 655 DRAQRLEECYEIIEKNLLLLGATAIEDRLQAGVPETIATLLKAEIKIWVLTGDKQETAIN 714
Query: 716 VSLSCGHFHRTMNILELINQKSDSECA---EQLRQLARRITEDHVIQHGLVVDGTSLSLA 772
+ SC + M ++ L D+ A + L + +++ + L++DG +L A
Sbjct: 715 IGYSCRLVSQNMALILLKEDSLDATRAAITQHCTDLGNLLGKENDV--ALIIDGHTLKYA 772
Query: 773 LR-EHEKLFMEVCRNCSAVLCCRMAPLQKAKVIRLIKISPEKPITLAVGDGANDVSMIQE 831
L E + F+++ +C AV+CCR++PLQK++++ ++K K ITLA+GDGANDV MIQ
Sbjct: 773 LSFEVRRSFLDLALSCKAVICCRVSPLQKSEIVDVVK-KRVKAITLAIGDGANDVGMIQT 831
Query: 832 AHVGIGIMGKEGRQAARNSDYAIARFKFLSKLLFVHGHFYYIRIATLVQYFFYKNVCFIT 891
AHVG+GI G EG QA NSDYAIA+F +L KLL VHG + Y R+ + Y FYKNV
Sbjct: 832 AHVGVGISGNEGMQATNNSDYAIAQFSYLEKLLLVHGAWSYNRVTKCILYCFYKNVVLYI 891
Query: 892 PQFLYQFYCLFSQQTLYDSVYLTLYNICFTSLPILIYSLLEQHVDPHVLQNKPTLYRDIS 951
+ + F FS Q L++ + LYN+ FT+LP + E+ + P LY+
Sbjct: 892 IELWFAFVNGFSGQILFERWCIGLYNVIFTALPPFTLGIFERSCTQESMLRFPQLYKITQ 951
Query: 952 KNRLLSIKTFLYWTILGFSHAFIFFFGSYLLIGKDTSLLGNGQMFGNWTFGTLVFTVMVI 1011
+ K F I H+ I F+ + DT +L +G G +V+T +V+
Sbjct: 952 NGEGFNTKVFWGHCINALVHSLILFWFPMKALEHDT-VLTSGHATDYLFVGNIVYTYVVV 1010
Query: 1012 TVTVKMALETHFWTWINHLVTWGSIIFYFVFSLFYGGILWPFLG-SQNMYFVFIQLLSSG 1070
TV +K LET WT +HL WGS++ + VF Y I WP + + +M +LSS
Sbjct: 1011 TVCLKAGLETTAWTKFSHLAVWGSMLTWLVFFGIYSTI-WPTIPIAPDMRGQATMVLSSA 1069
Query: 1071 SAWFAIILMVVTCLFLDIIKKVFDRHLHPTSTEKAQLTETNAGI 1114
W + L+ CL D+ + T E+ Q ET + +
Sbjct: 1070 HFWLGLFLVPTACLIEDVAWRAAKHTCKKTLLEEVQELETKSRV 1113
>gi|50083277 ATPase class I type 8B member 4 [Homo sapiens]
Length = 1192
Score = 660 bits (1702), Expect = 0.0
Identities = 398/1113 (35%), Positives = 617/1113 (55%), Gaps = 86/1113 (7%)
Query: 38 KFIDNRIISSKYTVWNFVPKNLFEQFRRVANFYFLIIFLVQLMIDTPTSP-VTSGLPLFF 96
++ DNRI +SKY + F+P NLFEQF+RVAN YFL + ++QL+ + + T+ +PL
Sbjct: 27 QYADNRIHTSKYNILTFLPINLFEQFQRVANAYFLCLLILQLIPEISSLTWFTTIVPLVL 86
Query: 97 VITVTAIKQGYEDWLRHNSDNEVNGAPVYVVRSGGLVKTRSKNIRVGDIVRIAKDEIFPA 156
VIT+TA+K +D+ RH SDN+VN V+ + L + N++VGDI+++ ++ A
Sbjct: 87 VITMTAVKDATDDYFRHKSDNQVNNRQSEVLINSKLQNEKWMNVKVGDIIKLENNQFVAA 146
Query: 157 DLVLLSSDRLDGSCHVTTASLDGETNLKTHVAVPETALLQT-VANLDTLVAVIECQQPEA 215
DL+LLSS G C+V TA LDGETNLK A+ T+ L ++ L ++ C+ P
Sbjct: 147 DLLLLSSSEPHGLCYVETAELDGETNLKVRHALSVTSELGADISRLAGFDGIVVCEVPNN 206
Query: 216 DLYRFMGRMIITQQMEEIVRPLGPESLLLRGARLKNTKEIFGVAVYTGMETKMALNYKSK 275
L +FMG + ++ L E ++LRG L+NT FG+ ++ G +TK+ N
Sbjct: 207 KLDKFMGIL----SWKDSKHSLNNEKIILRGCILRNTSWCFGMVIFAGPDTKLMQNSGKT 262
Query: 276 SQKRSAVEKSMNTFLIIYLVILISEAVISTILKYTWQAEEKWDEPWYNQKTEHQRNSSKI 335
KR+++++ MNT ++ LI +I I W+++ + + ++ S +
Sbjct: 263 KFKRTSIDRLMNTLVLWIFGFLICLGIILAIGNSIWESQT--GDQFRTFLFWNEGEKSSV 320
Query: 336 LRFISDFLAFLVLYNFIIPISLYVTVEMQKFLGSFFIGWDLDLYHEESDQKAQVNTSDLN 395
F +++++ N ++PISLYV+VE+ + S+FI WD +Y+ A T+ LN
Sbjct: 321 FSGFLTFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDRKMYYSRKAIPAVARTTTLN 380
Query: 396 EELGQVEYVFTDKTGTLTENEMQFRECSINGMKYQEINGRLVPEGP-TPDSSEGNLSYLS 454
EELGQ+EY+F+DKTGTLT+N M F+ CSING Y E++ L + T + + S S
Sbjct: 381 EELGQIEYIFSDKTGTLTQNIMTFKRCSINGRIYGEVHDDLDQKTEITQEKEPVDFSVKS 440
Query: 455 SLSH-LNNLSHLTTSSSFRTSPENETELIKEHDLFFKAVSLCHTVQISNVQTDCTGDGPW 513
H S P K H+ F + ++LCHTV
Sbjct: 441 QADREFQFFDHHLMESIKMGDP-------KVHE-FLRLLALCHTVMS------------- 479
Query: 514 QSNLAPSQLEYYASSPDEKALVEAAARIGIVFIGNSEETMEVKTLGKLERYKLLHILEFD 573
+ N A +L Y SPDE ALV AA G +F + ET+ ++ LG L Y+LL L+F+
Sbjct: 480 EENSA-GELIYQVQSPDEGALVTAARNFGFIFKSRTPETITIEELGTLVTYQLLAFLDFN 538
Query: 574 SDRRRMSVIVQAPSGEKLLFAKGAESSILPKCIGGE---IEKTRIHVDEFALKGLRTLCI 630
+ R+RMSVIV+ P G+ L++KGA++ + K + T H+ EFA +GLRTL I
Sbjct: 539 NTRKRMSVIVRNPEGQIKLYSKGADTILFEKLHPSNEVLLSLTSDHLSEFAGEGLRTLAI 598
Query: 631 AYRKFTSKEYEEIDKRIFEARTALQQREEKLAAVFQFIEKDLILLGATAVEDRLQDKVRE 690
AYR K ++E K + +A A ++R+E++A +++ IE+DL+LLGATAVED+LQ+ V E
Sbjct: 599 AYRDLDDKYFKEWHKMLEDANAATEERDERIAGLYEEIERDLMLLGATAVEDKLQEGVIE 658
Query: 691 TIEALRMAGIKVWVLTGDKHETAVSVSLSCGHFHRTMNILELINQKSDSECAEQLRQLA- 749
T+ +L +A IK+WVLTGDK ETA+++ +C MN + +I + E E+LR+
Sbjct: 659 TVTSLSLANIKIWVLTGDKQETAINIGYACNMLTDDMNDVFVIAGNNAVEVREELRKAKQ 718
Query: 750 ------RRITEDHVI-------------------QHGLVVDGTSLSLALREHEKL-FMEV 783
R + HV+ + L+++G SL+ AL K +E+
Sbjct: 719 NLFGQNRNFSNGHVVCEKKQQLELDSIVEETITGDYALIINGHSLAHALESDVKNDLLEL 778
Query: 784 CRNCSAVLCCRMAPLQKAKVIRLIKISPEKPITLAVGDGANDVSMIQEAHVGIGIMGKEG 843
C V+CCR+ PLQKA+V+ L+K +TLA+GDGANDVSMI+ AH+G+GI G+EG
Sbjct: 779 ACMCKTVICCRVTPLQKAQVVELVK-KYRNAVTLAIGDGANDVSMIKSAHIGVGISGQEG 837
Query: 844 RQAARNSDYAIARFKFLSKLLFVHGHFYYIRIATLVQYFFYKNVCFITPQFLYQFYCLFS 903
QA SDY+ A+F++L +LL VHG + Y R+ + YFFYKN F F + F+C FS
Sbjct: 838 LQAVLASDYSFAQFRYLQRLLLVHGRWSYFRMCKFLCYFFYKNFAFTLVHFWFGFFCGFS 897
Query: 904 QQTLYDSVYLTLYNICFTSLPILIYSLLEQHVDPHVLQNKPTLYRDISKNRLLSIKTFLY 963
QT+YD ++TL+NI +TSLP+L + +Q V + P LY+ N L + + F
Sbjct: 898 AQTVYDQWFITLFNIVYTSLPVLAMGIFDQDVSDQNSVDCPQLYKPGQLNLLFNKRKFFI 957
Query: 964 WTILGFSHAFIFFF----GSYLLIGKDTSLLGNGQMFGNWTFGTLVFTVMVITVTVKMAL 1019
+ G + + FF Y + G+D + + Q +F + T +VI V+V++AL
Sbjct: 958 CVLHGIYTSLVLFFIPYGAFYNVAGEDGQHIADYQ-----SFAVTMATSLVIVVSVQIAL 1012
Query: 1020 ETHFWTWINHLVTWGSIIFYF--VFSLFYGGIL------WPFLGSQNMYFVFIQLLSSGS 1071
+T +WT+INH+ WGSI YF +F++ GI +PF+G+ L+
Sbjct: 1013 DTSYWTFINHVFIWGSIAIYFSILFTMHSNGIFGIFPNQFPFVGNAR------HSLTQKC 1066
Query: 1072 AWFAIILMVVTCLFLDIIKKVFDRHLHPTSTEK 1104
W I+L V + + + L+PT +++
Sbjct: 1067 IWLVILLTTVASVMPVVAFRFLKVDLYPTLSDQ 1099
>gi|40316837 ATPase, class I, type 8B, member 2 isoform a [Homo
sapiens]
Length = 1223
Score = 654 bits (1687), Expect = 0.0
Identities = 399/1115 (35%), Positives = 608/1115 (54%), Gaps = 82/1115 (7%)
Query: 38 KFIDNRIISSKYTVWNFVPKNLFEQFRRVANFYFLIIFLVQLMIDTPT-SPVTSGLPLFF 96
++ N I +SKY + F+P NLFEQF+ VAN YFL + ++QL+ + S T+ +PL
Sbjct: 61 QYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVL 120
Query: 97 VITVTAIKQGYEDWLRHNSDNEVNGAPVYVVRSGGLVKTRSKNIRVGDIVRIAKDEIFPA 156
V+T+TA+K +D+ RH SDN+VN V+ +G L + + N+ VGDI+++ ++ A
Sbjct: 121 VLTITAVKDATDDYFRHKSDNQVNNRQSQVLINGILQQEQWMNVCVGDIIKLENNQFVAA 180
Query: 157 DLVLLSSDRLDGSCHVTTASLDGETNLKTHVAVPETALLQTVANLDTLVAVIECQQPEAD 216
DL+LLSS G C++ TA LDGETN+K A+P T+ L ++ L + C+ P
Sbjct: 181 DLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGDISKLAKFDGEVICEPPNNK 240
Query: 217 LYRFMGRMIITQQMEEIVRPLGPESLLLRGARLKNTKEIFGVAVYTGMETKMALNYKSKS 276
L +F G T +E PL +++LLRG L+NT+ FG+ ++ G +TK+ N
Sbjct: 241 LDKFSG----TLYWKENKFPLSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRTK 296
Query: 277 QKRSAVEKSMNTFLIIYLVILISEAVISTILKYTWQAEE--------KWDEPWYNQKTEH 328
KR+++++ MNT ++ L+ VI I W+ E WDE
Sbjct: 297 FKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGMRFQVYLPWDEAV------- 349
Query: 329 QRNSSKILRFISDFLAFLVLYNFIIPISLYVTVEMQKFLGSFFIGWDLDLYHEESDQKAQ 388
+S+ F+S F +++++ N ++PISLYV+VE+ + S+FI WD ++ + A+
Sbjct: 350 --DSAFFSGFLS-FWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDKKMFCMKKRTPAE 406
Query: 389 VNTSDLNEELGQVEYVFTDKTGTLTENEMQFRECSINGMKYQEIN---GRLVPEGPTPDS 445
T+ LNEELGQVEY+F+DKTGTLT+N M F +CSING Y ++ G G P+
Sbjct: 407 ARTTTLNEELGQVEYIFSDKTGTLTQNIMVFNKCSINGHSYGDVFDVLGHKAELGERPEP 466
Query: 446 SEGNLSYLSSLSHLNNLSHLTTSSSFRTSPENETELIKEHDLFFKAVSLCHTVQISNVQT 505
+ + + L+ L L + +E FF+ +SLCHTV
Sbjct: 467 VDFSFNPLADKKFLFWDPSLLEAVKIGDPHTHE---------FFRLLSLCHTVMSEEKNE 517
Query: 506 DCTGDGPWQSNLAPSQLEYYASSPDEKALVEAAARIGIVFIGNSEETMEVKTLGKLERYK 565
+L Y A SPDE ALV AA G VF + +T+ V +G Y+
Sbjct: 518 --------------GELYYKAQSPDEGALVTAARNFGFVFRSRTPKTITVHEMGTAITYQ 563
Query: 566 LLHILEFDSDRRRMSVIVQAPSGEKLLFAKGAESSILPKCIGGEIE---KTRIHVDEFAL 622
LL IL+F++ R+RMSVIV+ P G+ L+ KGA++ +L + E T H++E+A
Sbjct: 564 LLAILDFNNIRKRMSVIVRNPEGKIRLYCKGADTILLDRLHHSTQELLNTTMDHLNEYAG 623
Query: 623 KGLRTLCIAYRKFTSKEYEEIDKRIFEARTALQQREEKLAAVFQFIEKDLILLGATAVED 682
+GLRTL +AY+ + YEE +R +A A RE++LA++++ +E +++LLGATA+ED
Sbjct: 624 EGLRTLVLAYKDLDEEYYEEWAERRLQASLAQDSREDRLASIYEEVENNMMLLGATAIED 683
Query: 683 RLQDKVRETIEALRMAGIKVWVLTGDKHETAVSVSLSCGHFHRTMNILELINQKSDSECA 742
+LQ V ETI L +A IK+WVLTGDK ETAV++ SC M + ++ + E
Sbjct: 684 KLQQGVPETIALLTLANIKIWVLTGDKQETAVNIGYSCKMLTDDMTEVFIVTGHTVLEVR 743
Query: 743 EQLRQLARR-------------------------ITEDHVIQHGLVVDGTSLSLALREHE 777
E+LR+ + + E ++ LV++G SL+ AL
Sbjct: 744 EELRKAREKMMDSSRSVGNGFTYQDKLSSSKLTSVLEAVAGEYALVINGHSLAHALEADM 803
Query: 778 KL-FMEVCRNCSAVLCCRMAPLQKAKVIRLIKISPEKPITLAVGDGANDVSMIQEAHVGI 836
+L F+E C AV+CCR+ PLQKA+V+ L+K +K +TLA+GDGANDVSMI+ AH+G+
Sbjct: 804 ELEFLETACACKAVICCRVTPLQKAQVVELVK-KYKKAVTLAIGDGANDVSMIKTAHIGV 862
Query: 837 GIMGKEGRQAARNSDYAIARFKFLSKLLFVHGHFYYIRIATLVQYFFYKNVCFITPQFLY 896
GI G+EG QA SDY+ ++FKFL +LL VHG + Y+R+ + YFFYKN F F +
Sbjct: 863 GISGQEGIQAVLASDYSFSQFKFLQRLLLVHGRWSYLRMCKFLCYFFYKNFAFTMVHFWF 922
Query: 897 QFYCLFSQQTLYDSVYLTLYNICFTSLPILIYSLLEQHVDPHVLQNKPTLYRDISKNRLL 956
F+C FS QT+YD ++TLYNI +TSLP+L + +Q V P LY N L
Sbjct: 923 GFFCGFSAQTVYDQYFITLYNIVYTSLPVLAMGVFDQDVPEQRSMEYPKLYEPGQLNLLF 982
Query: 957 SIKTFLYWTILGFSHAFIFFFGSYLLIGKDTSLLGNGQMFGNWTFGTLVFTVMVITVTVK 1016
+ + F G + + FF Y + T G Q+ +F V T +VI V+V+
Sbjct: 983 NKREFFICIAQGIYTSVLMFFIPYGVFADATRDDGT-QLADYQSFAVTVATSLVIVVSVQ 1041
Query: 1017 MALETHFWTWINHLVTWGSIIFYF--VFSLFYGGILWPFLGSQNMYFVFIQLLSSGSAWF 1074
+ L+T +WT INH WGS+ YF +F++ G+ F L+ + W
Sbjct: 1042 IGLDTGYWTAINHFFIWGSLAVYFAILFAMHSNGLFDMFPNQFRFVGNAQNTLAQPTVWL 1101
Query: 1075 AIILMVVTCLFLDIIKKVFDRHLHPTSTEKAQLTE 1109
I+L V C+ + + +L P ++ + T+
Sbjct: 1102 TIVLTTVVCIMPVVAFRFLRLNLKPDLSDTVRYTQ 1136
>gi|5031697 ATPase, class I, type 8B, member 1 [Homo sapiens]
Length = 1251
Score = 622 bits (1604), Expect = e-178
Identities = 397/1128 (35%), Positives = 593/1128 (52%), Gaps = 98/1128 (8%)
Query: 38 KFIDNRIISSKYTVWNFVPKNLFEQFRRVANFYFLIIFLVQLMIDTPTSP-VTSGLPLFF 96
K+ +N I + KY + F+P NLFEQF+R AN YFL + ++Q + T T+ +PL
Sbjct: 91 KYANNAIKTYKYNAFTFIPMNLFEQFKRAANLYFLALLILQAVPQISTLAWYTTLVPLLV 150
Query: 97 VITVTAIKQGYEDWLRHNSDNEVNGAPVYVVRSGGLVKTRSKNIRVGDIVRIAKDEIFPA 156
V+ VTAIK +D RH D E+N V++ G + K I+VGD++R+ K++ PA
Sbjct: 151 VLGVTAIKDLVDDVARHKMDKEINNRTCEVIKDGRFKVAKWKEIQVGDVIRLKKNDFVPA 210
Query: 157 DLVLLSSDRLDGSCHVTTASLDGETNLKTHVAVPET-ALLQTVANLDTLVAVIECQQPEA 215
D++LLSS + C+V TA LDGETNLK +++ T LQ L T IEC++P
Sbjct: 211 DILLLSSSEPNSLCYVETAELDGETNLKFKMSLEITDQYLQREDTLATFDGFIECEEPNN 270
Query: 216 DLYRFMGRMIITQQMEEIVRPLGPESLLLRGARLKNTKEIFGVAVYTGMETKMALNYKSK 275
L +F G + PL + +LLRG ++NT G+ ++ G +TK+ N
Sbjct: 271 RLDKFTGTLF----WRNTSFPLDADKILLRGCVIRNTDFCHGLVIFAGADTKIMKNSGKT 326
Query: 276 SQKRSAVEKSMNTFLIIYLVILISEAVISTILKYTWQAEEKWDEPWYNQKTEHQRNSSKI 335
KR+ ++ MN + V+LI + I W+A+ + WY E S
Sbjct: 327 RFKRTKIDYLMNYMVYTIFVVLILLSAGLAIGHAYWEAQVG-NSSWYLYDGEDDTPS--- 382
Query: 336 LRFISDFLAFLVLYNFIIPISLYVTVEMQKFLGSFFIGWDLDLYHEESDQKAQVNTSDLN 395
R F ++++ N ++PISLYV+VE+ + S FI WDL +Y+ E D A+ T+ LN
Sbjct: 383 YRGFLIFWGYIIVLNTMVPISLYVSVEVIRLGQSHFINWDLQMYYAEKDTPAKARTTTLN 442
Query: 396 EELGQVEYVFTDKTGTLTENEMQFRECSINGMKYQEINGRLVPEGPTPDSSEGNLSYLSS 455
E+LGQ+ Y+F+DKTGTLT+N M F++C ING Y G D+S+ N + +
Sbjct: 443 EQLGQIHYIFSDKTGTLTQNIMTFKKCCINGQIY----------GDHRDASQHNHNKIEQ 492
Query: 456 LSHLNNLSHLTTSSSFRTSPENETELIKEHDL--FFKAVSLCHTVQISNVQTDCTGDGPW 513
+ N + + + + KE ++ FF +++CHTV + DG
Sbjct: 493 VDFSWNTYADGKLAFYDHYLIEQIQSGKEPEVRQFFFLLAVCHTVMVDRT------DG-- 544
Query: 514 QSNLAPSQLEYYASSPDEKALVEAAARIGIVFIGNSEETMEVKTLGKLERYKLLHILEFD 573
QL Y A+SPDE ALV AA G F+ ++ T+ + LG Y +L IL+F+
Sbjct: 545 -------QLNYQAASPDEGALVNAARNFGFAFLARTQNTITISELGTERTYNVLAILDFN 597
Query: 574 SDRRRMSVIVQAPSGEKLLFAKGAESSILPKC--IGGEIEKTRIHVDEFALKGLRTLCIA 631
SDR+RMS+IV+ P G L+ KGA++ I + + ++T+ +D FA + LRTLC+
Sbjct: 598 SDRKRMSIIVRTPEGNIKLYCKGADTVIYERLHRMNPTKQETQDALDIFANETLRTLCLC 657
Query: 632 YRKFTSKEYEEIDKRIFEARTALQQREEKLAAVFQFIEKDLILLGATAVEDRLQDKVRET 691
Y++ KE+ E +K+ A A R+E L V++ IEKDLILLGATA+ED+LQD V ET
Sbjct: 658 YKEIEEKEFTEWNKKFMAASVASTNRDEALDKVYEEIEKDLILLGATAIEDKLQDGVPET 717
Query: 692 IEALRMAGIKVWVLTGDKHETAVSVSLSCGHFHRTMNIL--ELINQKSDSECAEQ----- 744
I L A IK+WVLTGDK ETA ++ +C I E IN + Q
Sbjct: 718 ISKLAKADIKIWVLTGDKKETAENIGFACELLTEDTTICYGEDINSLLHARMENQRNRGG 777
Query: 745 -LRQLARRITEDHVIQHG---LVVDGTSLSLALRE------------------------- 775
+ A + E G L++ G+ L+ L E
Sbjct: 778 VYAKFAPPVQESFFPPGGNRALIITGSWLNEILLEKKTKRNKILKLKFPRTEEERRMRTQ 837
Query: 776 -----------HEKLFMEVCRNCSAVLCCRMAPLQKAKVIRLIKISPEKPITLAVGDGAN 824
+K F+++ CSAV+CCR+ P QKA V+ L+K +K ITLA+GDGAN
Sbjct: 838 SKRRLEAKKEQRQKNFVDLACECSAVICCRVTPKQKAMVVDLVK-RYKKAITLAIGDGAN 896
Query: 825 DVSMIQEAHVGIGIMGKEGRQAARNSDYAIARFKFLSKLLFVHGHFYYIRIATLVQYFFY 884
DV+MI+ AH+G+GI G+EG QA +SDY+ A+F++L +LL VHG + YIR+ ++YFFY
Sbjct: 897 DVNMIKTAHIGVGISGQEGMQAVMSSDYSFAQFRYLQRLLLVHGRWSYIRMCKFLRYFFY 956
Query: 885 KNVCFITPQFLYQFYCLFSQQTLYDSVYLTLYNICFTSLPILIYSLLEQHVDPHVLQNKP 944
KN F F Y F+ +S QT Y+ ++TLYN+ +TSLP+L+ LL+Q V + P
Sbjct: 957 KNFAFTLVHFWYSFFNGYSAQTAYEDWFITLYNVLYTSLPVLLMGLLDQDVSDKLSLRFP 1016
Query: 945 TLYRDISKNRLLSIKTFLYWTILGFSHAFIFFF---GSYL-LIGKDTSLLGNGQMFGNWT 1000
LY ++ L + K F + G + I FF G+YL +G+D + Q +
Sbjct: 1017 GLYIVGQRDLLFNYKRFFVSLLHGVLTSMILFFIPLGAYLQTVGQDGEAPSDYQ-----S 1071
Query: 1001 FGTLVFTVMVITVTVKMALETHFWTWINHLVTWGSIIFYF--VFSLFYGGILWPFLGSQN 1058
F + + +VITV ++ L+T +WT++N +GSI YF +F GI F +
Sbjct: 1072 FAVTIASALVITVNFQIGLDTSYWTFVNAFSIFGSIALYFGIMFDFHSAGIHVLFPSAFQ 1131
Query: 1059 MYFVFIQLLSSGSAWFAIILMVVTCLFLDIIKKVFDRHLHPTSTEKAQ 1106
L W IIL V CL + + + P+ ++K Q
Sbjct: 1132 FTGTASNALRQPYIWLTIILTVAVCLLPVVAIRFLSMTIWPSESDKIQ 1179
>gi|44888835 ATPase, class I, type 8B, member 3 [Homo sapiens]
Length = 1300
Score = 524 bits (1349), Expect = e-148
Identities = 355/1119 (31%), Positives = 569/1119 (50%), Gaps = 127/1119 (11%)
Query: 37 QKFIDNRIISSKYTVWNFVPKNLFEQFRRVANFYFLIIFLVQLMIDTPTSPVTS-GLPLF 95
+K+ N I ++KY ++F+P NL+EQF RV+N +FLII ++Q + D T P S P+
Sbjct: 131 KKYKTNVIRTAKYNFYSFLPLNLYEQFHRVSNLFFLIIIILQSIPDISTLPWFSLSTPMV 190
Query: 96 FVITVTAIKQGYEDWLRHNSDNEVNGAPVYVVRSGGLVKTRSKNIRVGDIVRIAKDEIFP 155
++ + A + +D RH SD +N P ++ + + +++ VGD+V + KD I P
Sbjct: 191 CLLFIRATRDLVDDMGRHKSDRAINNRPCQILMGKSFKQKKWQDLCVGDVVCLRKDNIVP 250
Query: 156 ADLVLLSSDRLDGSCHVTTASLDGETNLKTHVAVPETAL-LQTVANLDTLVAVIECQQPE 214
AD++LL+S C+V T +DGETNLK A+ T L T+ + + + C+ P
Sbjct: 251 ADMLLLASTEPSSLCYVETVDIDGETNLKFRQALMVTHKELATIKKMASFQGTVTCEAPN 310
Query: 215 ADLYRFMGRMIITQQMEEIVRPLGPESLLLRGARLKNTKEIFGVAVYTGMETKMALNYKS 274
+ ++ F+G + + + L +LLLRG R++NT +G+ +Y G +TK+ N
Sbjct: 311 SRMHHFVGCL----EWNDKKYSLDIGNLLLRGCRIRNTDTCYGLVIYAGFDTKIMKNCGK 366
Query: 275 KSQKRSAVEKSMNTFLIIYLVILISEAVISTILKYTW--QAEEKWDEPWYNQKTEHQRNS 332
KR+ ++ MN ++ VI IS ++ +L + + +E D +Y S
Sbjct: 367 IHLKRTKLDLLMNKLVV---VIFISVVLVCLVLAFGFGFSVKEFKDHHYYLSGVH---GS 420
Query: 333 SKILRFISDFLAFLVLYNFIIPISLYVTVEMQKFLGSFFIGWDLDLYHEESDQKAQVNTS 392
S F +FL+L + IP+S+++ E S FI WD+ +Y++ D A+ ++
Sbjct: 421 SVAAESFFVFWSFLILLSVTIPMSMFILSEFIYLGNSVFIDWDVQMYYKPQDVPAKARST 480
Query: 393 DLNEELGQVEYVFTDKTGTLTENEMQFRECSINGMKYQEINGRLVPEGPTP----DSSEG 448
LN+ LGQVEY+F+DKTGTLT+N + F +C I+G Y + P ++G
Sbjct: 481 SLNDHLGQVEYIFSDKTGTLTQNILTFNKCCISGRVYGPDSEATTRPKENPYLWNKFADG 540
Query: 449 NLSYLSSLSHLNNLSHLTTSSSFRTSPENETELIKEHDLFFKAVSLCHTVQISNVQTDCT 508
L L H L HL + N E ++E F++ +++CHTV + +
Sbjct: 541 KL-----LFHNAALLHLVRT--------NGDEAVRE---FWRLLAICHTVMVRESPRE-- 582
Query: 509 GDGPWQSNLAPSQLEYYASSPDEKALVEAAARIGIVFIGNSEETMEVKTLGKLERYKLLH 568
P QL Y A+SPDE ALV AA G VF+ +++T+ + LG+ Y++L
Sbjct: 583 ---------RPDQLLYQAASPDEGALVTAARNFGYVFLSRTQDTVTIMELGEERVYQVLA 633
Query: 569 ILEFDSDRRRMSVIVQAPSGEKLLFAKGAESSILPKC--IGGEIEKTRIHVDEFALKGLR 626
I++F+S R+RMSV+V+ P G L+ KGA++ I + G T + FA + LR
Sbjct: 634 IMDFNSTRKRMSVLVRKPEGAICLYTKGADTVIFERLHRRGAMEFATEEALAAFAQETLR 693
Query: 627 TLCIAYRKFTSKEYEEIDKRIFEARTALQQREEKLAAVFQFIEKDLILLGATAVEDRLQD 686
TLC+AYR+ YE+ +R EA LQ R + L LLGATA+EDRLQD
Sbjct: 694 TLCLAYREVAEDIYEDWQQRHQEASLLLQNRAQALQQ----------LLGATAIEDRLQD 743
Query: 687 KVRETIEALRMAGIKVWVLTGDKHETAVSVSLSCGHFHRTMNILE--------------- 731
V ETI+ L+ + IK+WVLTGDK ETAV++ +C M ILE
Sbjct: 744 GVPETIKCLKKSNIKIWVLTGDKQETAVNIGFACELLSENMLILEEKEISRILETYWENS 803
Query: 732 --LINQKSDSE------------------CAEQLRQLARRITEDHVIQH----------- 760
L+ ++S S+ ++ R LA+ + D Q
Sbjct: 804 NNLLTRESLSQVKLALVINGDFLDKLLVSLRKEPRALAQNVNMDEAWQELGQSRRDFLYA 863
Query: 761 ------------GLVVDGTSLSLALREHEKL----FMEVCRNCSAVLCCRMAPLQKAKVI 804
L S A R E L F+++ C AV+CCR+ P QKA ++
Sbjct: 864 RRLSLLCRRFGLPLAAPPAQDSRARRSSEVLQERAFVDLASKCQAVICCRVTPKQKALIV 923
Query: 805 RLIKISPEKPITLAVGDGANDVSMIQEAHVGIGIMGKEGRQAARNSDYAIARFKFLSKLL 864
L+K + +TLA+GDGAND++MI+ A VG+G+ G+EG QA +NSD+ + +F FL +LL
Sbjct: 924 ALVK-KYHQVVTLAIGDGANDINMIKTADVGVGLAGQEGMQAVQNSDFVLGQFCFLQRLL 982
Query: 865 FVHGHFYYIRIATLVQYFFYKNVCFITPQFLYQFYCLFSQQTLYDSVYLTLYNICFTSLP 924
VHG + Y+RI ++YFFYK++ + Q + Y F+ Q LY+ +L L+N+ +++LP
Sbjct: 983 LVHGRWSYVRICKFLRYFFYKSMASMMVQVWFACYNGFTGQPLYEGWFLALFNLLYSTLP 1042
Query: 925 ILIYSLLEQHVDPHVLQNKPTLYRDISKNRLLSIKTFLYWTILGFSHAFIFFFGSYLLIG 984
+L L EQ V KP LY K+ L + F+ G + + + FF + L I
Sbjct: 1043 VLYIGLFEQDVSAEQSLEKPELYVVGQKDELFNYWVFVQAIAHGVTTSLVNFFMT-LWIS 1101
Query: 985 KDTSLLGNGQMFGNWTFGTLVFTVMVITVTVKMALETHFWTWINHLVTWGSIIFYFVFSL 1044
+DT+ G + +F +V ++++T+++ L +WT + S+ FY + +
Sbjct: 1102 RDTA--GPASFSDHQSFAVVVALSCLLSITMEVILIIKYWTALCVATILLSLGFYAIMTT 1159
Query: 1045 FYGGILWPFLGSQNMY---FVFIQLLSSGSAWFAIILMV 1080
W F S + + + ++SS S ++L V
Sbjct: 1160 TTQS-FWLFRVSPTTFPFLYADLSVMSSPSILLVVLLSV 1197
>gi|41327760 ATPase, class II, type 9B [Homo sapiens]
Length = 1147
Score = 459 bits (1181), Expect = e-129
Identities = 325/1080 (30%), Positives = 533/1080 (49%), Gaps = 81/1080 (7%)
Query: 37 QKFIDNRIISSKYTVWNFVPKNLFEQFRRVANFYFLIIFLVQLMIDTPTSPV-TSGLPLF 95
+K N I + KY V+ F+P L+EQF+ N YFL+I Q + + T PL
Sbjct: 128 EKHPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFLVISCSQFVPALKIGYLYTYWAPLG 187
Query: 96 FVITVTAIKQGYEDWLRHNSDNEVNGAPVYVVRSGGLVKTRSKNIRVGDIVRIAKDEIFP 155
FV+ VT ++ +++ R D EVN + G V+ +S +I+VGD++ + K++ P
Sbjct: 188 FVLAVTMTREAIDEFRRFQRDKEVNSQLYSKLTVRGKVQVKSSDIQVGDLIIVEKNQRIP 247
Query: 156 ADLVLLSSDRLDGSCHVTTASLDGETNLKTHVAVPETALLQTVANLDTLVAVIECQQPEA 215
+D+V L + GSC + T LDGET+ K VAV T L + +L ++ A + Q+P+
Sbjct: 248 SDMVFLRTSEKAGSCFIRTDQLDGETDWKLKVAVSCTQQLPALGDLFSISAYVYAQKPQM 307
Query: 216 DLYRFMGRMIITQQMEEIVRPLGPESLLLRGARLKNTKEIFGVAVYTGMETKMALNYKSK 275
D++ F G I L E+ L + + + + GV +YTG ET+ +N +
Sbjct: 308 DIHSFEGTFTREDSDPPIHESLSIENTLW-ASTIVASGTVIGVVIYTGKETRSVMNTSNP 366
Query: 276 SQKRSAVEKSMNTFLIIYLVILISEAVISTILKYTWQAEEKWDEPWYNQKTEHQRNSSKI 335
K ++ +N + L++ +++ L + + PWY
Sbjct: 367 KNKVGLLDLELNRLTKALFLALVALSIVMVTL-------QGFVGPWYR------------ 407
Query: 336 LRFISDFLAFLVLYNFIIPISLYVTVEMQKFLGSFFIGWDLDLYHEESDQKAQVNTSDLN 395
+ FL+L+++IIPISL V ++M G GW + +E+ V TS +
Sbjct: 408 -----NLFRFLLLFSYIIPISLRVNLDM----GKAVYGWMM--MKDENIPGTVVRTSTIP 456
Query: 396 EELGQVEYVFTDKTGTLTENEMQFRECSINGMKYQEINGRLVPEGPTPDSSEGNL----S 451
EELG++ Y+ TDKTGTLT+NEM F+ + + Y T D + ++ S
Sbjct: 457 EELGRLVYLLTDKTGTLTQNEMIFKRLHLGTVSYG---------ADTMDEIQSHVRDSYS 507
Query: 452 YLSSLSHLNNLSHLTTSSSFRTSPENETELIKEHDLFFKAVSLCHTV----QISNVQTDC 507
+ S + NN + ++P+ + KA+ LCH V + T+
Sbjct: 508 QMQSQAGGNNTGSTPLRKAQSSAPKVRKSVSSRIHEAVKAIVLCHNVTPVYESRAGVTEE 567
Query: 508 TGDGPWQSNLAPSQLEYYASSPDEKALVEAAARIGIVFIGNSEETMEVKT-LGKLERYKL 566
T + + Y ASSPDE ALV+ +G+ + +M++KT G++ + +
Sbjct: 568 TEFAEADQDFSDENRTYQASSPDEVALVQWTESVGLTLVSRDLTSMQLKTPSGQVLSFCI 627
Query: 567 LHILEFDSDRRRMSVIVQAPSGEKLLF-AKGAESSILPKCIGGEIEKTRIHVDEFALKGL 625
L + F S+ +RM VIV+ S ++ F KGA+ ++ P I + A +GL
Sbjct: 628 LQLFPFTSESKRMGVIVRDESTAEITFYMKGADVAMSP--IVQYNDWLEEECGNMAREGL 685
Query: 626 RTLCIAYRKFTSKEYEEIDKRIFEARTALQQREEKLAAVFQFIEKDLILLGATAVEDRLQ 685
RTL +A + T ++Y++ + R +A+ ++ R K+AAV + +E+++ LL T VED+LQ
Sbjct: 686 RTLVVAKKALTEEQYQDFESRYTQAKLSMHDRSLKVAAVVESLEREMELLCLTGVEDQLQ 745
Query: 686 DKVRETIEALRMAGIKVWVLTGDKHETAVSVSLSCGHFHRTMNILELINQKSDSECAEQL 745
VR T+E LR AGIK+W+LTGDK ETA ++ S RT +I S E +L
Sbjct: 746 ADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSSHLVSRTQDIHIFRQVTSRGEAHLEL 805
Query: 746 RQLARRITEDHVIQHGLVVDGTSLSLALREHEKLFMEVCRNCSAVLCCRMAPLQKAKVIR 805
R+ LV+ G SL + L+ +E F+E+ C AV+CCR +P QKA+++
Sbjct: 806 NAFRRK------HDCALVISGDSLEVCLKYYEHEFVELACQCPAVVCCRCSPTQKARIVT 859
Query: 806 LIKISPEKPITLAVGDGANDVSMIQEAHVGIGIMGKEGRQAARNSDYAIARFKFLSKLLF 865
L++ + T A+GDG NDVSMIQ A GIGI GKEG+QA+ +D++I +F+ + +LL
Sbjct: 860 LLQQHTGRR-TCAIGDGGNDVSMIQAADCGIGIEGKEGKQASLAADFSITQFRHIGRLLM 918
Query: 866 VHGHFYYIRIATLVQYFFYKNVCFITPQFLYQFYCLFSQQTLYDSVYLTLYNICFTSLPI 925
VHG Y R A L Q+ ++ + T Q ++ F+ LY + Y +T P+
Sbjct: 919 VHGRNSYKRSAALGQFVMHRGLIISTMQAVFSSVFYFASVPLYQGFLMVGYATIYTMFPV 978
Query: 926 LIYSLLEQHVDPHVLQNKPTLYRDISKNRLLSIKTFLYWTILGFSHAFIFFFGSYLLIGK 985
+L+Q V P + P LY+D++K R LS KTFL W ++ I +G+ +L
Sbjct: 979 FSL-VLDQDVKPEMAMLYPELYKDLTKGRSLSFKTFLIWVLISIYQGGILMYGALVLFES 1037
Query: 986 DTSLLGNGQMFGNWTFGTLVFTVMVITVTVKMALETHFWTW---INHLVTWGSIIFYFVF 1042
+ + + FT +++T + +AL W W + ++ G + F
Sbjct: 1038 EFVHV-----------VAISFTALILTELLMVALTVRTWHWLMVVAEFLSLGCYVSSLAF 1086
Query: 1043 SLFYGGILWPFLGSQNMYFVFIQLLSSGS-AWFAIILMVVTCLFLDIIKKVFDRHLHPTS 1101
Y GI G+ F+ + +++ + W + VV+CL L ++ K R L P S
Sbjct: 1087 LNEYFGIGRVSFGA----FLDVAFITTVTFLWKVSAITVVSCLPLYVL-KYLRRKLSPPS 1141
>gi|65301139 ATPase, class II, type 9A [Homo sapiens]
Length = 1047
Score = 455 bits (1171), Expect = e-127
Identities = 319/1067 (29%), Positives = 524/1067 (49%), Gaps = 79/1067 (7%)
Query: 37 QKFIDNRIISSKYTVWNFVPKNLFEQFRRVANFYFLIIFLVQLMIDTPTSPV-TSGLPLF 95
Q++ N I + KY + F+P LF QF+ N YFL++ Q + + + T +PL
Sbjct: 51 QRYPRNVINNQKYNFFTFLPGVLFNQFKYFFNLYFLLLACSQFVPEMRLGALYTYWVPLG 110
Query: 96 FVITVTAIKQGYEDWLRHNSDNEVNGAPVYVVRSGGLVKTRSKNIRVGDIVRIAKDEIFP 155
FV+ VT I++ E+ + D EVN + + G VK +S NI+VGD++ + K++ P
Sbjct: 111 FVLAVTVIREAVEEIRCYVRDKEVNSQVYSRLTARGTVKVKSSNIQVGDLIIVEKNQRVP 170
Query: 156 ADLVLLSSDRLDGSCHVTTASLDGETNLKTHVAVPETALLQTVANLDTLVAVIECQQPEA 215
AD++ L + +GSC + T LDGET+ K + V T L T A+L + + + ++P
Sbjct: 171 ADMIFLRTSEKNGSCFLRTDQLDGETDWKLRLPVACTQRLPTAADLLQIRSYVYAEEPNI 230
Query: 216 DLYRFMGRMIITQQMEEIVRPLGPESLLLRGARLKNTKEIFGVAVYTGMETKMALNYKSK 275
D++ F+G I L E+ L G + + + GV +YTG E + +N +
Sbjct: 231 DIHNFVGTFTREDSDPPISESLSIENTLWAGTVVASGT-VVGVVLYTGRELRSVMNTSNP 289
Query: 276 SQKRSAVEKSMNTFLIIYLVILISEAVISTILKYTWQAEEKWDEPWYNQKTEHQRNSSKI 335
K + +N I L+ +++ L++ + WY Q
Sbjct: 290 RSKIGLFDLEVNCLTKILFGALVVVSLVMVALQH-------FAGRWYLQ----------- 331
Query: 336 LRFISDFLAFLVLYNFIIPISLYVTVEMQKFLGSFFIGWDLDLYHEESDQKAQVNTSDLN 395
+ FL+L++ IIPISL V ++M K + S+ I D + V +S +
Sbjct: 332 ------IIRFLLLFSNIIPISLRVNLDMGKIVYSWVIRRDSKI------PGTVVRSSTIP 379
Query: 396 EELGQVEYVFTDKTGTLTENEMQFRECSINGMKYQEINGRLVPEGPTPDSSEGNLSYLSS 455
E+LG++ Y+ TDKTGTLT+NEM F+ + + Y DS + S++ S
Sbjct: 380 EQLGRISYLLTDKTGTLTQNEMIFKRLHLGTVAYGL------------DSMDEVQSHIFS 427
Query: 456 LSHLNNLSHLTTSSSFRTSPENETELIKEHDLFFKAVSLCHTVQISNVQTDCTGDGPWQS 515
+ + T+ T + H+ KA++LCH V T +
Sbjct: 428 IYTQQSQDPPAQKGPTLTTKVRRTMSSRVHEAV-KAIALCHNVTPVYESNGVTDQAEAEK 486
Query: 516 NLAPSQLEYYASSPDEKALVEAAARIGIVFIGNSEETMEVKTLG-KLERYKLLHILEFDS 574
S Y ASSPDE ALV+ +G+ +G + +M+++T G ++ + +L I F
Sbjct: 487 QYEDSCRVYQASSPDEVALVQWTESVGLTLVGRDQSSMQLRTPGDQILNFTILQIFPFTY 546
Query: 575 DRRRMSVIVQAPS-GEKLLFAKGAESSILPKCIGGEIEKTRIHVDEFALKGLRTLCIAYR 633
+ +RM +IV+ S GE + KGA+ ++ I + A +GLR L +A +
Sbjct: 547 ESKRMGIIVRDESTGEITFYMKGAD--VVMAGIVQYNDWLEEECGNMAREGLRVLVVAKK 604
Query: 634 KFTSKEYEEIDKRIFEARTALQQREEKLAAVFQFIEKDLILLGATAVEDRLQDKVRETIE 693
++Y++ + R +A+ ++ R K+A V + +E ++ LL T VED+LQ VR T+E
Sbjct: 605 SLAEEQYQDFEARYVQAKLSVHDRSLKVATVIESLEMEMELLCLTGVEDQLQADVRPTLE 664
Query: 694 ALRMAGIKVWVLTGDKHETAVSVSLSCGHFHRTMNILELINQKSDSECAEQLRQLARRIT 753
LR AGIKVW+LTGDK ETA + + R +I + E +L R+
Sbjct: 665 TLRNAGIKVWMLTGDKLETATCTAKNAHLVTRNQDIHVFRLVTNRGEAHLELNAFRRKH- 723
Query: 754 EDHVIQHGLVVDGTSLSLALREHEKLFMEVCRNCSAVLCCRMAPLQKAKVIRLIKISPEK 813
LV+ G SL + L+ +E FME+ C AV+CCR AP QKA+++RL++ K
Sbjct: 724 -----DCALVISGDSLEVCLKYYEYEFMELACQCPAVVCCRCAPTQKAQIVRLLQERTGK 778
Query: 814 PITLAVGDGANDVSMIQEAHVGIGIMGKEGRQAARNSDYAIARFKFLSKLLFVHGHFYYI 873
+T AVGDG NDVSMIQE+ G+G+ GKEG+QA+ +D++I +FK L +LL VHG Y
Sbjct: 779 -LTCAVGDGGNDVSMIQESDCGVGVEGKEGKQASLAADFSITQFKHLGRLLMVHGRNSYK 837
Query: 874 RIATLVQYFFYKNVCFITPQFLYQFYCLFSQQTLYDSVYLTLYNICFTSLPILIYSLLEQ 933
R A L Q+ ++++C T Q ++ F+ LY + Y+ +T P+ +L++
Sbjct: 838 RSAALSQFVIHRSLCISTMQAVFSSVFYFASVPLYQGFLIIGYSTIYTMFPVFSL-VLDK 896
Query: 934 HVDPHVLQNKPTLYRDISKNRLLSIKTFLYWTILGFSHAFIFFFGSYLLIGKDTSLLGNG 993
V V P LY+D+ K R LS KTFL W ++ +G+ LL + +
Sbjct: 897 DVKSEVAMLYPELYKDLLKGRPLSYKTFLIWVLISIYQGSTIMYGALLLFESEFVHI--- 953
Query: 994 QMFGNWTFGTLVFTVMVITVTVKMALETHFWTWINHLVTWGSIIFYFVFSLFYGGILWPF 1053
+ FT +++T + +AL W W+ + S+ Y +F L F
Sbjct: 954 --------VAISFTSLILTELLMVALTIQTWHWLMTVAELLSLACYIASLVF----LHEF 1001
Query: 1054 LGSQNMYFVFIQLLSSGSAWFAIILMVVTCLFLDIIKKVFDRHLHPT 1100
+ ++YF+ + W ++ +V+CL L ++K + R P+
Sbjct: 1002 I---DVYFI----ATLSFLWKVSVITLVSCLPLYVLKYLRRRFSPPS 1041
>gi|222352161 ATPase, class V, type 10D [Homo sapiens]
Length = 1426
Score = 367 bits (942), Expect = e-101
Identities = 251/739 (33%), Positives = 378/739 (51%), Gaps = 69/739 (9%)
Query: 411 TLTENEMQFRECSINGMKYQEINGRLVPEGPTPDSSEGNLSYLSSLSHLN----NLSHLT 466
+L E + F+ S+ +N P P++ L S + + +S +
Sbjct: 621 SLEEIKSLFQRWSVRRSSSPSLNSGKEPSSGVPNAFVSRLPLFSRMKPASPVEEEVSQVC 680
Query: 467 TSSSFRTSPENETELIKEHDLFFKAVSLCHTVQISNVQTDCTGDGPWQSNLAPSQLEYYA 526
S +S TE K+H + N + + P NL Y A
Sbjct: 681 ESPQCSSSSACCTETEKQHG----------DAGLLNGKAESLPGQPLACNLC-----YEA 725
Query: 527 SSPDEKALVEAAARIGIVFIGNSEETMEVK--TLGKLERYKLLHILEFDSDRRRMSVIVQ 584
SPDE ALV AA + E + V LG L ++LLHIL FDS R+RMSV+V+
Sbjct: 726 ESPDEAALVYAARAYQCTLRSRTPEQVMVDFAALGPLT-FQLLHILPFDSVRKRMSVVVR 784
Query: 585 AP-SGEKLLFAKGAESSILPKCI-----GGEIEK--------TRIHVDEFALKGLRTLCI 630
P S + +++ KGA+S I+ G +EK T+ H+D++A +GLRTLCI
Sbjct: 785 HPLSNQVVVYTKGADSVIMELLSVASPDGASLEKQQMIVREKTQKHLDDYAKQGLRTLCI 844
Query: 631 AYRKFTSKEYEEIDKRIFEARTALQQREEKLAAVFQFIEKDLILLGATAVEDRLQDKVRE 690
A + + EY E + F A T++ REE L +E L LLGAT +EDRLQ+ V E
Sbjct: 845 AKKVMSDTEYAEWLRNHFLAETSIDNREELLLESAMRLENKLTLLGATGIEDRLQEGVPE 904
Query: 691 TIEALRMAGIKVWVLTGDKHETAVSVSLSCGHFHRTMNILELINQKSD------SECAEQ 744
+IEAL AGIK+W+LTGDK ETAV+++ +C + L Q D S ++
Sbjct: 905 SIEALHKAGIKIWMLTGDKQETAVNIAYACKLLEPDDKLFILNTQSKDACGMLMSTILKE 964
Query: 745 LRQLARRITE---------------DHVIQHGLVVDGTSLSLALREH-EKLFMEVCRNCS 788
L++ + + E D ++ GL++ G +L AL+E +K F+E+ C
Sbjct: 965 LQKKTQALPEQVSLSEDLLQPPVPRDSGLRAGLIITGKTLEFALQESLQKQFLELTSWCQ 1024
Query: 789 AVLCCRMAPLQKAKVIRLIKISPEKPITLAVGDGANDVSMIQEAHVGIGIMGKEGRQAAR 848
AV+CCR PLQK++V++L++ S + +TLA+GDGANDVSMIQ A +GIG+ G+EG QA
Sbjct: 1025 AVVCCRATPLQKSEVVKLVR-SHLQVMTLAIGDGANDVSMIQVADIGIGVSGQEGMQAVM 1083
Query: 849 NSDYAIARFKFLSKLLFVHGHFYYIRIATLVQYFFYKNVCFITPQFLYQFYCLFSQQTLY 908
SD+A+++FK LSKLL VHGH+ Y R++ ++ YFFYKNV ++ F YQF+C FS ++
Sbjct: 1084 ASDFAVSQFKHLSKLLLVHGHWCYTRLSNMILYFFYKNVAYVNLLFWYQFFCGFSGTSMT 1143
Query: 909 DSVYLTLYNICFTSLPILIYSLLEQHVDPHVLQNKPTLYRDISKNRLLSIKTFLYWTILG 968
D L +N+ FTS P +IY +LE+ V L P LYR K+ TF +
Sbjct: 1144 DYWVLIFFNLLFTSAPPVIYGVLEKDVSAETLMQLPELYRSGQKSEAYLPHTFWITLLDA 1203
Query: 969 FSHAFIFFFGSYLLI-GKDTSLLGNGQMFGNWTFGTLVFTVMVITVTVKMALETHFWTWI 1027
F + + FF Y G DT + + FG + T + V + + +E+ TWI
Sbjct: 1204 FYQSLVCFFVPYFTYQGSDTDI---------FAFGNPLNTAALFIVLLHLVIESKSLTWI 1254
Query: 1028 NHLVTWGSIIFYFVFSLFYGGILWPFLGSQNMYFVFIQLLSSGSAWFAIILMVVTCLFLD 1087
+ LV GSI+ YF+F++ +G + N Y++ + + + IL L
Sbjct: 1255 HLLVIIGSILSYFLFAIVFGAMCVTCNPPSNPYWIMQEHMLDPVFYLVCILTTSIALLPR 1314
Query: 1088 IIKKVFDRHLHPTSTEKAQ 1106
+ +V L P+ +A+
Sbjct: 1315 FVYRVLQGSLFPSPILRAK 1333
Score = 256 bits (653), Expect = 1e-67
Identities = 151/403 (37%), Positives = 231/403 (57%), Gaps = 12/403 (2%)
Query: 39 FIDNRIISSKYTVWNFVPKNLFEQFRRVANFYFLIIFLVQL--MIDTPTSPVTSGLPLFF 96
+++NRI ++KYT+ NFVP+NLFEQF R AN YFL + ++ +++ +T LPL
Sbjct: 71 YVNNRIRTTKYTLLNFVPRNLFEQFHRAANLYFLFLVVLNWVPLVEAFQKEITM-LPLVV 129
Query: 97 VITVTAIKQGYEDWLRHNSDNEVNG--APVYVVRSGGLVKTRSKNIRVGDIVRIAKDEIF 154
V+T+ AIK G ED+ ++ D ++N VY + + K++ VGD +R++ +E+
Sbjct: 130 VLTIIAIKDGLEDYRKYKIDKQINNLITKVYSRKEKKYIDRCWKDVTVGDFIRLSCNEVI 189
Query: 155 PADLVLLSSDRLDGSCHVTTASLDGETNLKTHVAVPETALLQTVANLDTLVAVIECQQPE 214
PAD+VLL S DG CH+ T+ LDGE+NLK V A + + + + IEC+ P
Sbjct: 190 PADMVLLFSTDPDGICHIETSGLDGESNLKQRQVVRGYAEQDSEVDPEKFSSRIECESPN 249
Query: 215 ADLYRFMGRMIITQQMEEIVRPLGPESLLLRGARLKNTKEIFGVAVYTGMETKMALNYKS 274
DL RF G + +E V L E+LLLRG ++NT+ + G+ VY G ETK LN
Sbjct: 250 NDLSRFRG--FLEHSNKERVG-LSKENLLLRGCTIRNTEAVVGIVVYAGHETKAMLNNSG 306
Query: 275 KSQKRSAVEKSMNTFLIIYLVILISEAVISTILKYTWQAE-EKWDEPWYNQKTEHQRNSS 333
KRS +E+ NT ++ +++L+ + + W + EK ++N S
Sbjct: 307 PRYKRSKLERRANTDVLWCVMLLVIMCLTGAVGHGIWLSRYEKMH--FFNVPEPDGHIIS 364
Query: 334 KILRFISDFLAFLVLYNFIIPISLYVTVEMQKFLGSFFIGWDLDLYHEESDQKAQVNTSD 393
+L F ++L +IPISLYV++E+ K +FI D+D Y+E+ D Q +
Sbjct: 365 PLLAGFYMFWTMIILLQVLIPISLYVSIEIVKLGQIYFIQSDVDFYNEKMDSIVQCRALN 424
Query: 394 LNEELGQVEYVFTDKTGTLTENEMQFRECSINGMKY-QEINGR 435
+ E+LGQ++Y+F+DKTGTLTEN+M FR CS+ G Y E N R
Sbjct: 425 IAEDLGQIQYLFSDKTGTLTENKMVFRRCSVAGFDYCHEENAR 467
>gi|149944474 ATPase, class V, type 10B [Homo sapiens]
Length = 1461
Score = 361 bits (927), Expect = 2e-99
Identities = 226/612 (36%), Positives = 338/612 (55%), Gaps = 51/612 (8%)
Query: 515 SNLAPSQLEYYASSPDEKALVEAAARIGIVFIGNSEETMEVKT-LGKLERYKLLHILEFD 573
++LA + Y A SPDE ALV AA + + E + V+ G + LL L FD
Sbjct: 708 TDLARPEFCYEAESPDEAALVHAAHAYSFTLVSRTPEQVTVRLPQGTCLTFSLLCTLGFD 767
Query: 574 SDRRRMSVIVQAP-SGEKLLFAKGAESSIL-----PKCIGG-EIEK--------TRIHVD 618
S R+RMSV+V+ P +GE +++ KGA+S I+ P C+ +EK T+ H+D
Sbjct: 768 SVRKRMSVVVRHPLTGEIVVYTKGADSVIMDLLEDPACVPDINMEKKLRKIRARTQKHLD 827
Query: 619 EFALKGLRTLCIAYRKFTSKEYEEIDKRIFEARTALQQREEKLAAVFQFIEKDLILLGAT 678
+A GLRTLCIA + + +++ EA +L R+E L Q +E L LLGAT
Sbjct: 828 LYARDGLRTLCIAKKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQLTLLGAT 887
Query: 679 AVEDRLQDKVRETIEALRMAGIKVWVLTGDKHETAVSVSLSCGHFHRTMNILELINQKSD 738
+EDRLQ+ V +TI LR AGI++WVLTGDK ETAV+++ SC ++T + + + +
Sbjct: 888 GIEDRLQEGVPDTIATLREAGIQLWVLTGDKQETAVNIAHSCRLLNQTDTVYTINTENQE 947
Query: 739 S-----ECA----EQLRQLAR---------------RITEDHVI-QHGLVVDGTSLSLAL 773
+ CA +Q R+L + IT + V+ + GLV+DG +L+
Sbjct: 948 TCESILNCALEELKQFRELQKPDRKLFGFRLPSKTPSITSEAVVPEAGLVIDGKTLNAIF 1007
Query: 774 R-EHEKLFMEVCRNCSAVLCCRMAPLQKAKVIRLIKISPEKPITLAVGDGANDVSMIQEA 832
+ + EK F+E+ + C +VLCCR PLQK+ +++L++ + +TL++GDGANDVSMIQ A
Sbjct: 1008 QGKLEKKFLELTQYCRSVLCCRSTPLQKSMIVKLVR-DKLRVMTLSIGDGANDVSMIQAA 1066
Query: 833 HVGIGIMGKEGRQAARNSDYAIARFKFLSKLLFVHGHFYYIRIATLVQYFFYKNVCFITP 892
+GIGI G+EG QA +SD+AI RFK L KLL VHGH+ Y R+A +V Y+ YKNVC++
Sbjct: 1067 DIGIGISGQEGMQAVMSSDFAITRFKHLKKLLLVHGHWCYSRLARMVVYYLYKNVCYVNL 1126
Query: 893 QFLYQFYCLFSQQTLYDSVYLTLYNICFTSLPILIYSLLEQHVDPHVLQNKPTLYRDISK 952
F YQF+C FS T+ D + +N+ FTSLP L++ +L++ + L P LY+
Sbjct: 1127 LFWYQFFCGFSSSTMIDYWQMIFFNLFFTSLPPLVFGVLDKDISAETLLALPELYKSGQN 1186
Query: 953 NRLLSIKTFLYWTILGFSHAFIFFFGSYLLIGKDTSLLGNGQMFGNWTFGTLVFTVMVIT 1012
+ ++ TF + F + I FF YL G +TFGT + T+ + T
Sbjct: 1187 SECYNLSTFWISMVDAFYQSLICFFIPYLAY--------KGSDIDVFTFGTPINTISLTT 1238
Query: 1013 VTVKMALETHFWTWINHLVTWGSIIFYFVFSLFYGGILWPFLGSQNMYFVFIQLLSSGSA 1072
+ + A+E WT + +V GS + YF+ SL Y N Y+V LS+ +
Sbjct: 1239 ILLHQAMEMKTWTIFHGVVLLGSFLMYFLVSLLYNATCVICNSPTNPYWVMEGQLSNPTF 1298
Query: 1073 WFAIILMVVTCL 1084
+ L V L
Sbjct: 1299 YLVCFLTPVVAL 1310
Score = 255 bits (652), Expect = 2e-67
Identities = 157/433 (36%), Positives = 231/433 (53%), Gaps = 19/433 (4%)
Query: 28 FPQNGLY------TPQKFIDNRIISSKYTVWNFVPKNLFEQFRRVANFYFLIIFLVQLMI 81
FP N ++ +++ NR ++KYT++ F+P+NLFEQF R AN YFL + ++ M
Sbjct: 49 FPNNSIFHQDWEEVSRRYPGNRTCTTKYTLFTFLPRNLFEQFHRWANLYFLFLVILNWM- 107
Query: 82 DTPTSPV----TSGLPLFFVITVTAIKQGYEDWLRHNSDNEVN--GAPVYVVRSGGLVKT 135
P+ V + LPL V+ V IK G ED+ RH D +N +Y + V+
Sbjct: 108 --PSMEVFHREITMLPLAIVLFVIMIKDGMEDFKRHRFDKAINCSNIRIYERKEQTYVQK 165
Query: 136 RSKNIRVGDIVRIAKDEIFPADLVLLSSDRLDGSCHVTTASLDGETNLKTHVAVPETALL 195
K++RVGD +++ +EI PAD++LL S +G CH+ TASLDGETNLK V +
Sbjct: 166 CWKDVRVGDFIQMKCNEIVPADILLLFSSDPNGICHLETASLDGETNLKQRCVVKGFSQQ 225
Query: 196 QTVANLDTLVAVIECQQPEADLYRFMGRMIITQQMEEIVRPLGPESLLLRGARLKNTKEI 255
+ + I C++P L +F G M + ++ G ESLLLRG ++NT+
Sbjct: 226 EVQFEPELFHNTIVCEKPNNHLNKFKGYM---EHPDQTRTGFGCESLLLRGCTIRNTEMA 282
Query: 256 FGVAVYTGMETKMALNYKSKSQKRSAVEKSMNTFLIIYLVILISEAVISTILKYTWQAEE 315
G+ +Y G ETK LN KRS +E+ MN + + ILI +I + W
Sbjct: 283 VGIVIYAGHETKAMLNNSGPRYKRSKIERRMNIDIFFCIGILILMCLIGAVGHSIWNGTF 342
Query: 316 KWDEPWYNQKTEHQRNSSKILRFISDFLAFLVLYNFIIPISLYVTVEMQKFLGSFFIGWD 375
+ P+ S + F FL ++L +IPISLYV++E+ K FF+ D
Sbjct: 343 EEHPPFDVPDANGSFLPSALGGFYM-FLTMIILLQVLIPISLYVSIELVKLGQVFFLSND 401
Query: 376 LDLYHEESDQKAQVNTSDLNEELGQVEYVFTDKTGTLTENEMQFRECSINGMKYQEINGR 435
LDLY EE+D Q ++ E+LGQ++Y+F+DKTGTLTEN+M FR C+I G +Y
Sbjct: 402 LDLYDEETDLSIQCRALNIAEDLGQIQYIFSDKTGTLTENKMVFRRCTIMGSEYSHQENA 461
Query: 436 LVPEGPTPDSSEG 448
E P S+G
Sbjct: 462 KRLETPKELDSDG 474
>gi|14424433 ATPase, class V, type 10A [Homo sapiens]
Length = 1499
Score = 355 bits (912), Expect = 1e-97
Identities = 247/741 (33%), Positives = 381/741 (51%), Gaps = 82/741 (11%)
Query: 442 TPDSSEGNLSYLSSLSHLNNLSHLTTSSSFRTSPENETELIKEHDLFFKAVSLCHTVQIS 501
TP S + SL+ N SH SSF ++P ++ L++ + + S + S
Sbjct: 614 TPSCLTSGCSSIGSLA-ANKSSH-KLGSSFPSTPSSDGMLLRLEERLGQPTSAIASNGYS 671
Query: 502 NVQTDCTGDGPWQSNLAPSQ-----LEYYASSPDEKALVEAAARIGIVFIG--NSEETME 554
+ Q D W S LA Q L Y A SPDE ALV AA V + + + ++E
Sbjct: 672 S-QAD-----NWASELAQEQESERELRYEAESPDEAALVYAARAYNCVLVERLHDQVSVE 725
Query: 555 VKTLGKLERYKLLHILEFDSDRRRMSVIVQAPSGEKL-LFAKGAES---SILPKCIGGEI 610
+ LG+L ++LLH L FDS R+RMSV+++ P +++ ++ KGA+S +L C +
Sbjct: 726 LPHLGRLT-FELLHTLGFDSVRKRMSVVIRHPLTDEINVYTKGADSVVMDLLQPCSSVDA 784
Query: 611 E---------KTRIHVDEFALKGLRTLCIAYRKFTSKEYEEIDKRIFEARTALQQREEKL 661
KT+ +++ +A +GLRTLCIA R + +EY + EA ++L+ EE L
Sbjct: 785 RGRHQKKIRSKTQNYLNVYAAEGLRTLCIAKRVLSKEEYACWLQSHLEAESSLENSEELL 844
Query: 662 AAVFQFIEKDLILLGATAVEDRLQDKVRETIEALRMAGIKVWVLTGDKHETAVSVSLSCG 721
+E +L LLGAT +EDRLQD V ETI LR AG+++WVLTGDK ETAV+++ +C
Sbjct: 845 FQSAIRLETNLHLLGATGIEDRLQDGVPETISKLRQAGLQIWVLTGDKQETAVNIAYACK 904
Query: 722 HFHRTMNILELINQKSDSECAEQLRQL-----------ARRITEDHVIQH---------- 760
++ L N S CA L Q A T+ V
Sbjct: 905 LLDHDEEVITL-NATSQEACAALLDQCLCYVQSRGLQRAPEKTKGKVSMRFSSLCPPSTS 963
Query: 761 -------GLVVDGTSLSLALREH-EKLFMEVCRNCSAVLCCRMAPLQKAKVIRLIKISPE 812
LV+DG SL+ AL ++ E F+ + + C +VLCCR PLQK+ V++L++ S
Sbjct: 964 TASGRRPSLVIDGRSLAYALEKNLEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLVR-SKL 1022
Query: 813 KPITLAVGDGANDVSMIQEAHVGIGIMGKEGRQAARNSDYAIARFKFLSKLLFVHGHFYY 872
K +TLA+GDGANDVSMIQ A VG+GI G+EG QA SD+A+ +F++L +LL +HGH+ Y
Sbjct: 1023 KAMTLAIGDGANDVSMIQVADVGVGISGQEGMQAVMASDFAVPKFRYLERLLILHGHWCY 1082
Query: 873 IRIATLVQYFFYKNVCFITPQFLYQFYCLFSQQTLYDSVYLTLYNICFTSLPILIYSLLE 932
R+A +V YFFYKN F+ F +QF+C FS T+ D YL +N+ F+SLP L+ +L+
Sbjct: 1083 SRLANMVLYFFYKNTMFVGLLFWFQFFCGFSASTMIDQWYLIFFNLLFSSLPPLVTGVLD 1142
Query: 933 QHVDPHVLQNKPTLYRDISKNRLLSIKTF-------LYWTILGFSHAFIFFFGSYLLIGK 985
+ V +VL P LY+ +TF + +++ FS ++ ++ S
Sbjct: 1143 RDVPANVLLTNPQLYKSGQNMEEYRPRTFWFNMADAAFQSLVCFSIPYLAYYDS------ 1196
Query: 986 DTSLLGNGQMFGNWTFGTLVFTVMVITVTVKMALETHFWTWINHLVTWGSIIFYFVFSLF 1045
N +F T+GT + T+ ++T + + +ET WTW+N + S++ +F +L
Sbjct: 1197 ------NVDLF---TWGTPIVTIALLTFLLHLGIETKTWTWLNWITCGFSVLLFFTVALI 1247
Query: 1046 YGGILWPFLGSQNMYFVFIQLLSSGSAWFAIILMVVTCLFLDIIKKVFDRHLHPTSTEKA 1105
Y N Y+ LL + ++ V L + + + PT + A
Sbjct: 1248 YNASCATCYPPSNPYWTMQALLGDPVFYLTCLMTPVAALLPRLFFRSLQGRVFPTQLQLA 1307
Query: 1106 QLTETNAGIKCLDSMCCFPEG 1126
+ + +C F +G
Sbjct: 1308 RQLTRKSPRRCSAPKETFAQG 1328
Score = 281 bits (718), Expect = 3e-75
Identities = 182/524 (34%), Positives = 283/524 (54%), Gaps = 26/524 (4%)
Query: 37 QKFIDNRIISSKYTVWNFVPKNLFEQFRRVANFYFLIIFLVQLMIDTPT-SPVTSGLPLF 95
Q DNR+ ++KYT+ +F+PKNLFEQF R AN YF+ I L+ + P + P+
Sbjct: 57 QHLADNRLKTTKYTLLSFLPKNLFEQFHRPANVYFVFIALLNFVPAVNAFQPGLALAPVL 116
Query: 96 FVITVTAIKQGYEDWLRHNSDNEVN--GAPVYVVRSGGLVKTRSKNIRVGDIVRIAKDEI 153
F++ +TA + +ED+ RH SD+++N G V+ V K I VGD VR+ +EI
Sbjct: 117 FILAITAFRDLWEDYSRHRSDHKINHLGCLVFSREEKKYVNRFWKEIHVGDFVRLRCNEI 176
Query: 154 FPADLVLLSSDRLDGSCHVTTASLDGETNLKTHVAVPETALLQTVANLDTLVAVIECQQP 213
FPAD++LLSS DG CH+ TA+LDGETNLK V + L + N T +VIEC++P
Sbjct: 177 FPADILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNPLTFTSVIECEKP 236
Query: 214 EADLYRFMGRMIITQQMEEIVRPLGPESLLLRGARLKNTKEIFGVAVYTGMETKMALNYK 273
DL RF G +I + L E+LLLRG L+NT + G+ +Y G ETK LN
Sbjct: 237 NNDLSRFRGCIIHDNGKKA---GLYKENLLLRGCTLRNTDAVVGIVIYAGHETKALLNNS 293
Query: 274 SKSQKRSAVEKSMNTFLIIYLVILISEAVISTILK--YTWQAEEKWDEPWYNQKTEHQRN 331
KRS +E+ MN ++ +++L+ ++ S + + W+ +EK +Y K++ +
Sbjct: 294 GPRYKRSKLERQMNCDVLWCVLLLVCMSLFSAVGHGLWIWRYQEK-KSLFYVPKSDGS-S 351
Query: 332 SSKILRFISDFLAFLVLYNFIIPISLYVTVEMQKFLGSFFIGWDLDLYHEESDQKAQVNT 391
S + + FL +++ +IPISLYV++E+ K +FI D+ LY EE+D + Q
Sbjct: 352 LSPVTAAVYSFLTMIIVLQVLIPISLYVSIEIVKACQVYFINQDMQLYDEETDSQLQCRA 411
Query: 392 SDLNEELGQVEYVFTDKTGTLTENEMQFRECSINGMKY-QEINGRLVPEGPTPDSSE--- 447
++ E+LGQ++Y+F+DKTGTLTEN+M FR C+++G++Y + N + + DS E
Sbjct: 412 LNITEDLGQIQYIFSDKTGTLTENKMVFRRCTVSGVEYSHDANAQRLARYQEADSEEEEV 471
Query: 448 ----GNLSYLSSL-SHLN-NLSHLTTSSSFRTSPENETELIKEHDLFFKAVSLCHTVQIS 501
G++S S+ SH + + H T S+ + E K + K HT S
Sbjct: 472 VPRGGSVSQRGSIGSHQSVRVVHRTQSTKSHRRTGSRAE-AKRASMLSK-----HTAFSS 525
Query: 502 NVQTDCTGDGPWQSNLAPSQLEYYASSPDEKALVEAAARIGIVF 545
++ D T D ++ + E L + + VF
Sbjct: 526 PMEKDITPDPKLLEKVSECDKSLAVARHQEHLLAHLSPELSDVF 569
>gi|55743077 ATPase, class I, type 8B, member 2 isoform b [Homo
sapiens]
Length = 387
Score = 200 bits (509), Expect = 6e-51
Identities = 129/397 (32%), Positives = 208/397 (52%), Gaps = 47/397 (11%)
Query: 38 KFIDNRIISSKYTVWNFVPKNLFEQFRRVANFYFLIIFLVQLMIDTPT-SPVTSGLPLFF 96
++ N I +SKY + F+P NLFEQF+ VAN YFL + ++QL+ + S T+ +PL
Sbjct: 28 QYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVL 87
Query: 97 VITVTAIKQGYEDWLRHNSDNEVNGAPVYVVRSGGLVKTRSKNIRVGDIVRIAKDEIFPA 156
V+T+TA+K +D+ RH SDN+VN V+ +G L + + N+ VGDI+++ ++ A
Sbjct: 88 VLTITAVKDATDDYFRHKSDNQVNNRQSQVLINGILQQEQWMNVCVGDIIKLENNQFVAA 147
Query: 157 DLVLLSSDRLDGSCHVTTASLDGETNLKTHVAVPETALLQTVANLDTLVAVIECQQPEAD 216
DL+LLSS G C++ TA LDGETN+K A+P T+ L ++ L + C+ P
Sbjct: 148 DLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGDISKLAKFDGEVICEPPNNK 207
Query: 217 LYRFMGRMIITQQMEEIVRPLGPESLLLRGARLKNTKEIFGVAVYTGMETKMALNYKSKS 276
L +F G T +E PL +++LLRG L+NT+ FG+ ++ G +TK+ N
Sbjct: 208 LDKFSG----TLYWKENKFPLSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRTK 263
Query: 277 QKRSAVEKSMNTFLIIYLVILISEAVISTILKYTWQAEE--------KWDEPWYNQKTEH 328
KR+++++ MNT ++ L+ VI I W+ E WDE
Sbjct: 264 FKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGMRFQVYLPWDE--------- 314
Query: 329 QRNSSKILRFISDFLAFLVLYNFIIPISLYVTVEMQKFLGSFFIGWDLDLYHEESDQKAQ 388
+S+ F+S F +++++ N ++PISLYV +++ S + W L
Sbjct: 315 AVDSAFFSGFLS-FWSYIIILNTVVPISLYV-----RYVPS--LTWGLS----------- 355
Query: 389 VNTSDLNEELGQVEYVFTDKTGTLTENEMQFRECSIN 425
E G +E F+ K +L NE C++N
Sbjct: 356 ------RESGGPIELFFSMKMKSLRSNEKSSSSCTVN 386
>gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo
sapiens]
Length = 1198
Score = 94.4 bits (233), Expect = 6e-19
Identities = 188/908 (20%), Positives = 333/908 (36%), Gaps = 199/908 (21%)
Query: 92 LPLFFVITVTAIKQGYEDWLRHNSDNEVNGA-----PVYVVRSGGLVKTRSKNIRVGDIV 146
L + V+ VTA + DW + + VVR+G +V+ I VGDI
Sbjct: 159 LSVICVVLVTA----FNDWSKEKQFRGLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIA 214
Query: 147 RIAKDEIFPADLVLLSSDRLDGSCHVTTASLDGETNLKTHVAVPETALLQTVANLD---- 202
++ ++ PAD + + + L + +SL GE++ + LL ++
Sbjct: 215 QVKYGDLLPADGLFIQGNDLK----IDESSLTGESDQVRKSVDKDPMLLSGTHVMEGSGR 270
Query: 203 TLVAVIECQQPEADLYRFMGRMIITQQMEEIVRPLGPESLLLRGARLKNTKEIFGVAVYT 262
LV + ++ +G ++ ++ K K+ G A
Sbjct: 271 MLVTAVGVNSQTGIIFTLLGAGGEEEEKKD-----------------KKAKQQDGAAAME 313
Query: 263 GMETKMALNYKSKSQKRSAVEKSMNTFL---IIYLVILISEA--------VISTILKYTW 311
K A + +K++++ K + L + L + I +A VI +L +T
Sbjct: 314 MQPLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTV 373
Query: 312 QAEEKWDEPWYNQKTEHQRNSSKILRFISDFLAFLVLYNFIIPISLYVTVEMQKFLGSFF 371
+PW + T ++ F+ F FII +++ V + +
Sbjct: 374 DTFVVNKKPWLPECTPV---------YVQYFVKF-----FIIGVTVLVVAVPEGLPLAVT 419
Query: 372 IGWDLDLYHEESDQKAQVNTSDLNEELGQVEYVFTDKTGTLTENEMQFRECSINGMKYQE 431
I + D V D E +G + +DKTGTLT N M + + + Y+E
Sbjct: 420 ISLAYSVKKMMKDNNL-VRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKE 478
Query: 432 INGRLVPEGPTPDSSEGNLSYLSSLSHLNNLSHLTTSSSFRTS---PENETELIKEHDLF 488
I PD S N + L ++ + +S++ T PE E L +
Sbjct: 479 I----------PDPSSINTKTMELL-----INAIAINSAYTTKILPPEKEGALPR----- 518
Query: 489 FKAVSLCHTVQISNVQTDCTGDGPWQSNLAPSQLEYYASSPDEKALVEAAARIGIVFIGN 548
Q+ N +T+C G F+ +
Sbjct: 519 ----------QVGN-KTECGLLG---------------------------------FVLD 534
Query: 549 SEETMEVKTLGKLERYKLLHILEFDSDRRRMSVIVQAPSGEKLLFAKGAESSILPKCI-- 606
++ E ++ KL + F+S R+ MS +++ P +++KGA +L KC
Sbjct: 535 LKQDYE-PVRSQMPEEKLYKVYTFNSVRKSMSTVIKLPDESFRMYSKGASEIVLKKCCKI 593
Query: 607 ---GGEI---------EKTRIHVDEFALKGLRTLCIAYRKFTSKEYEEIDKRIFEARTAL 654
GE E + ++ A GLRT+C+AYR F S + D
Sbjct: 594 LNGAGEPRVFRPRDRDEMVKKVIEPMACDGLRTICVAYRDFPSSPEPDWDNE-------- 645
Query: 655 QQREEKLAAVFQFIEKDLILLGATAVEDRLQDKVRETIEALRMAGIKVWVLTGDKHETAV 714
I +L + +ED ++ +V E I + AGI V ++TGD TA
Sbjct: 646 -----------NDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTAR 694
Query: 715 SVSLSCGHFHRTMNILELINQKSDSECAEQLRQLARRITEDHVIQHGLVVDGTSLSLALR 774
++++ CG H + L L E ++R I ++ +
Sbjct: 695 AIAIKCGIIHPGEDFLCL----EGKEFNRRIRNEKGEIEQERI----------------- 733
Query: 775 EHEKLFMEVCRNCSAVLCCRMAPLQKAKVIRLIKIS---PEKPITLAVGDGANDVSMIQE 831
+K++ ++ + R +P K +++ I S ++ + GDG ND +++
Sbjct: 734 --DKIWPKL------RVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKK 785
Query: 832 AHVGIGIMGKEGRQAARN-SDYAIARFKFLSKLLFV-HGHFYYIRIATLVQYFFYKNVCF 889
A VG MG G A+ SD + F S + V G Y I+ +Q+ NV
Sbjct: 786 ADVGFA-MGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVA 844
Query: 890 ITPQFLYQFYCLFSQQTLYDSVYLTLYNICFTSLPILIYSLLEQHV--DPHVLQNKPTLY 947
+ F S +++ L F SL + E + P+ +NKP +
Sbjct: 845 VIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYG-RNKPLIS 903
Query: 948 RDISKNRL 955
R + KN L
Sbjct: 904 RTMMKNIL 911
>gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo
sapiens]
Length = 1170
Score = 91.7 bits (226), Expect = 4e-18
Identities = 195/918 (21%), Positives = 342/918 (37%), Gaps = 201/918 (21%)
Query: 91 GLPLFFVITVTAIKQGYEDWLRHNSDNEVN-----GAPVYVVRSGGLVKTRSKNIRVGDI 145
G + F + + + + DW + + ++R+G L++ I VGDI
Sbjct: 152 GAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQKFSIIRNGQLIQLPVAEIVVGDI 211
Query: 146 VRIAKDEIFPADLVLLSSD-------RLDGSCHVTTASLDGETNLK--THVAVPETALLQ 196
++ ++ PAD +L+ + L G SLD + L THV ++
Sbjct: 212 AQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDPMLLSGTHVMEGSGRMVV 271
Query: 197 TVANLDTLVAVIECQQPEADLYRFMGRMIITQQMEEIVRPLGPESLLLRGARLKNTKEIF 256
T +++ +I + + + + E + G + + T++
Sbjct: 272 TAVGVNSQTGII------------LTLLGVNEDDEGEKKKKGKKQGVPENRNKAKTQD-- 317
Query: 257 GVAV-YTGMETKMALNYKSKSQKRSAVEKSMNTFL---IIYLVILISEA--------VIS 304
GVA+ + ++ ++ + K +K V K + L + L + I +A V
Sbjct: 318 GVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKLTRLAVQIGKAGLLMSALTVFI 377
Query: 305 TILKYTWQAEEKWDEPWYNQKTEHQRNSSKILRFISDFLAFLVLYNFIIPISLYVTVEMQ 364
IL + PW + T +I F+ F FII I++ V +
Sbjct: 378 LILYFVIDNFVINRRPWLPECTPI---------YIQYFVKF-----FIIGITVLVVAVPE 423
Query: 365 KFLGSFFIGWDLDLYHEESDQKAQVNTSDLNEELGQVEYVFTDKTGTLTENEMQFRECSI 424
+ I + D V D E +G + +DKTGTLT N M + I
Sbjct: 424 GLPLAVTISLAYSVKKMMKDNNL-VRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYI 482
Query: 425 NGMKYQEINGRLVPEGPTPDSSEGNLSYLSSLSHL--NNLSHLTTSSSFRTSPENETELI 482
G+ Y++I P+PD +L + L N +S + +S PE E L
Sbjct: 483 GGIHYRQI--------PSPDV------FLPKVLDLIVNGISINSAYTSKILPPEKEGGLP 528
Query: 483 KEHDLFFKAVSLCHTVQISNVQTDCTGDGPWQSNLAPSQLEYYASSPDEKALVEAAARIG 542
+ Q+ N +T+C A +G
Sbjct: 529 R---------------QVGN-KTEC-------------------------------ALLG 541
Query: 543 IVFIGNSEETMEVKTLGKLERYKLLHILEFDSDRRRMSVIVQAPSGEKLLFAKGAESSIL 602
F+ + ++ + ++ KL + F+S R+ MS +++ P+G +++KGA IL
Sbjct: 542 --FVTDLKQDYQA-VRNEVPEEKLYKVYTFNSVRKSMSTVIRNPNGGFRMYSKGASEIIL 598
Query: 603 PKC-----IGGEI---------EKTRIHVDEFALKGLRTLCIAYRKFTSKEYEEIDKRIF 648
KC GE + R ++ A GLRT+CIAYR F E
Sbjct: 599 RKCNRILDRKGEAVPFKNKDRDDMVRTVIEPMACDGLRTICIAYRDFDDTE--------- 649
Query: 649 EARTALQQREEKLAAVFQFIEKDLILLGATAVEDRLQDKVRETIEALRMAGIKVWVLTGD 708
+ E L +L + +ED ++ +V + I + AGI V ++TGD
Sbjct: 650 ---PSWDNENEILT--------ELTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGD 698
Query: 709 KHETAVSVSLSCGHFHRTMNILELINQKSDSECAE--QLRQLARRITEDHVIQHGLVVDG 766
TA +++ CG ++ D C E + +L R + V Q L
Sbjct: 699 NINTARAIATKCG----------ILTPGDDFLCLEGKEFNRLIRN-EKGEVEQEKL---- 743
Query: 767 TSLSLALREHEKLFMEVCRNCSAVLCCRMAPLQKAKVIRLI---KISPEKPITLAVGDGA 823
+K++ ++ + R +P K +++ I + + + GDG
Sbjct: 744 ----------DKIWPKL------RVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDGT 787
Query: 824 NDVSMIQEAHVGIGIMGKEGRQAARN-SDYAIARFKFLSKLLFV-HGHFYYIRIATLVQY 881
ND +++A VG MG G A+ SD + F S + V G Y I+ +Q+
Sbjct: 788 NDGPALKKADVGFA-MGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQF 846
Query: 882 FFYKNVCFITPQFLYQFYCLFSQQTLYDSVYLTLYNICFTSLPIL----IYSLLEQHVDP 937
NV + F S +++ L F SL + SLL++ P
Sbjct: 847 QLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRR--P 904
Query: 938 HVLQNKPTLYRDISKNRL 955
+ +NKP + R + KN L
Sbjct: 905 YG-RNKPLISRTMMKNIL 921
>gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo
sapiens]
Length = 1205
Score = 91.7 bits (226), Expect = 4e-18
Identities = 195/918 (21%), Positives = 342/918 (37%), Gaps = 201/918 (21%)
Query: 91 GLPLFFVITVTAIKQGYEDWLRHNSDNEVN-----GAPVYVVRSGGLVKTRSKNIRVGDI 145
G + F + + + + DW + + ++R+G L++ I VGDI
Sbjct: 152 GAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQKFSIIRNGQLIQLPVAEIVVGDI 211
Query: 146 VRIAKDEIFPADLVLLSSD-------RLDGSCHVTTASLDGETNLK--THVAVPETALLQ 196
++ ++ PAD +L+ + L G SLD + L THV ++
Sbjct: 212 AQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDPMLLSGTHVMEGSGRMVV 271
Query: 197 TVANLDTLVAVIECQQPEADLYRFMGRMIITQQMEEIVRPLGPESLLLRGARLKNTKEIF 256
T +++ +I + + + + E + G + + T++
Sbjct: 272 TAVGVNSQTGII------------LTLLGVNEDDEGEKKKKGKKQGVPENRNKAKTQD-- 317
Query: 257 GVAV-YTGMETKMALNYKSKSQKRSAVEKSMNTFL---IIYLVILISEA--------VIS 304
GVA+ + ++ ++ + K +K V K + L + L + I +A V
Sbjct: 318 GVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKLTRLAVQIGKAGLLMSALTVFI 377
Query: 305 TILKYTWQAEEKWDEPWYNQKTEHQRNSSKILRFISDFLAFLVLYNFIIPISLYVTVEMQ 364
IL + PW + T +I F+ F FII I++ V +
Sbjct: 378 LILYFVIDNFVINRRPWLPECTPI---------YIQYFVKF-----FIIGITVLVVAVPE 423
Query: 365 KFLGSFFIGWDLDLYHEESDQKAQVNTSDLNEELGQVEYVFTDKTGTLTENEMQFRECSI 424
+ I + D V D E +G + +DKTGTLT N M + I
Sbjct: 424 GLPLAVTISLAYSVKKMMKDNNL-VRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYI 482
Query: 425 NGMKYQEINGRLVPEGPTPDSSEGNLSYLSSLSHL--NNLSHLTTSSSFRTSPENETELI 482
G+ Y++I P+PD +L + L N +S + +S PE E L
Sbjct: 483 GGIHYRQI--------PSPDV------FLPKVLDLIVNGISINSAYTSKILPPEKEGGLP 528
Query: 483 KEHDLFFKAVSLCHTVQISNVQTDCTGDGPWQSNLAPSQLEYYASSPDEKALVEAAARIG 542
+ Q+ N +T+C A +G
Sbjct: 529 R---------------QVGN-KTEC-------------------------------ALLG 541
Query: 543 IVFIGNSEETMEVKTLGKLERYKLLHILEFDSDRRRMSVIVQAPSGEKLLFAKGAESSIL 602
F+ + ++ + ++ KL + F+S R+ MS +++ P+G +++KGA IL
Sbjct: 542 --FVTDLKQDYQA-VRNEVPEEKLYKVYTFNSVRKSMSTVIRNPNGGFRMYSKGASEIIL 598
Query: 603 PKC-----IGGEI---------EKTRIHVDEFALKGLRTLCIAYRKFTSKEYEEIDKRIF 648
KC GE + R ++ A GLRT+CIAYR F E
Sbjct: 599 RKCNRILDRKGEAVPFKNKDRDDMVRTVIEPMACDGLRTICIAYRDFDDTE--------- 649
Query: 649 EARTALQQREEKLAAVFQFIEKDLILLGATAVEDRLQDKVRETIEALRMAGIKVWVLTGD 708
+ E L +L + +ED ++ +V + I + AGI V ++TGD
Sbjct: 650 ---PSWDNENEILT--------ELTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGD 698
Query: 709 KHETAVSVSLSCGHFHRTMNILELINQKSDSECAE--QLRQLARRITEDHVIQHGLVVDG 766
TA +++ CG ++ D C E + +L R + V Q L
Sbjct: 699 NINTARAIATKCG----------ILTPGDDFLCLEGKEFNRLIRN-EKGEVEQEKL---- 743
Query: 767 TSLSLALREHEKLFMEVCRNCSAVLCCRMAPLQKAKVIRLI---KISPEKPITLAVGDGA 823
+K++ ++ + R +P K +++ I + + + GDG
Sbjct: 744 ----------DKIWPKL------RVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDGT 787
Query: 824 NDVSMIQEAHVGIGIMGKEGRQAARN-SDYAIARFKFLSKLLFV-HGHFYYIRIATLVQY 881
ND +++A VG MG G A+ SD + F S + V G Y I+ +Q+
Sbjct: 788 NDGPALKKADVGFA-MGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQF 846
Query: 882 FFYKNVCFITPQFLYQFYCLFSQQTLYDSVYLTLYNICFTSLPIL----IYSLLEQHVDP 937
NV + F S +++ L F SL + SLL++ P
Sbjct: 847 QLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRR--P 904
Query: 938 HVLQNKPTLYRDISKNRL 955
+ +NKP + R + KN L
Sbjct: 905 YG-RNKPLISRTMMKNIL 921
>gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo
sapiens]
Length = 1220
Score = 90.9 bits (224), Expect = 6e-18
Identities = 190/916 (20%), Positives = 343/916 (37%), Gaps = 199/916 (21%)
Query: 92 LPLFFVITVTAIKQGYEDWLRHNSDNEVNGA-----PVYVVRSGGLVKTRSKNIRVGDIV 146
L + V+ VTA + DW + + V+R+G L++ + VGDI
Sbjct: 162 LSVICVVLVTA----FNDWSKEKQFRGLQSRIEQEQKFTVIRNGQLLQVPVAALVVGDIA 217
Query: 147 RIAKDEIFPADLVLLSSDRLDGSCHVTTASLDGETNLKTHVAVPETALLQTVANLD---- 202
++ ++ PAD VL+ ++ L + +SL GE++ A + LL ++
Sbjct: 218 QVKYGDLLPADGVLIQANDLK----IDESSLTGESDHVRKSADKDPMLLSGTHVMEGSGR 273
Query: 203 TLVAVIECQQPEADLYRFMGRMIITQQMEEIVRPLGPESLLLRGARLKNTKEIFGVAVYT 262
+V + ++ +G ++ E+ + + + ++ K K+ VA+
Sbjct: 274 MVVTAVGVNSQTGIIFTLLGAG--GEEEEKKDKKGKQQDGAMESSQTKAKKQDGAVAMEM 331
Query: 263 G---------METKMALNYKSKSQKRSAVEKSMNTFLI-----------IYLVILISEAV 302
ME + + +++S ++ + + I ++IL+ V
Sbjct: 332 QPLKSAEGGEMEEREKKKANAPKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFV 391
Query: 303 ISTILKY--TWQAEEKWDEPWYNQKTEHQRNSSKILRFISDFLAFLVLYNFIIPISLYVT 360
I T + TW AE P Y Q F+ F+ + + +P L +
Sbjct: 392 IETFVVEGRTWLAE---CTPVYVQY------------FVKFFIIGVTVLVVAVPEGLPLA 436
Query: 361 VEMQKFLGSFFIGWDLDLYHEESDQKAQVNTSDLNEELGQVEYVFTDKTGTLTENEMQFR 420
V + + + + ++++ V D E +G + +DKTGTLT N M
Sbjct: 437 VTIS-------LAYSVKKMMKDNNL---VRHLDACETMGNATAICSDKTGTLTTNRMTVV 486
Query: 421 ECSINGMKYQEINGRLVPEGPTPDSSEGNLSYLSSLSHLNNLSHLTTSSSFRTSPENETE 480
+ + Y+EI P TP L L H +++ T+ PE E
Sbjct: 487 QSYLGDTHYKEIPA---PSALTP-------KILDLLVHAISINSAYTTKIL--PPEKEGA 534
Query: 481 LIKEHDLFFKAVSLCHTVQISNVQTDCTGDGPWQSNLAPSQLEYYASSPDEKALVEAAAR 540
L + Q+ N +T+C A
Sbjct: 535 LPR---------------QVGN-KTEC-------------------------------AL 547
Query: 541 IGIVFIGNSEETMEVKTLGKLERYKLLHILEFDSDRRRMSVIVQAPSGEKLLFAKGAESS 600
+G V + + V+ ++ KL + F+S R+ MS +++ P G LF+KGA
Sbjct: 548 LGFV-LDLKRDFQPVRE--QIPEDKLYKVYTFNSVRKSMSTVIRMPDGGFRLFSKGASEI 604
Query: 601 ILPKCIG-----GEI---------EKTRIHVDEFALKGLRTLCIAYRKFTSKEYEEIDKR 646
+L KC GE+ + R ++ A GLRT+CIAYR F++ + + D
Sbjct: 605 LLKKCTNILNSNGELRGFRPRDRDDMVRKIIEPMACDGLRTICIAYRDFSAGQEPDWDNE 664
Query: 647 IFEARTALQQREEKLAAVFQFIEKDLILLGATAVEDRLQDKVRETIEALRMAGIKVWVLT 706
+ DL + +ED ++ +V E I + AGI V ++T
Sbjct: 665 -------------------NEVVGDLTCIAVVGIEDPVRPEVPEAIRKCQRAGITVRMVT 705
Query: 707 GDKHETAVSVSLSCGHFHRTMNILELINQKSDSECAEQLRQLARRITEDHVIQHGLVVDG 766
GD TA +++ CG +I D C E ++ RRI +
Sbjct: 706 GDNINTARAIAAKCG----------IIQPGEDFLCLEG-KEFNRRIRNE----------- 743
Query: 767 TSLSLALREHEKLFMEVCRNCSAVLCCRMAPLQKAKVIRLI---KISPEKPITLAVGDGA 823
+ +K++ ++ + R +P K +++ I ++ + GDG
Sbjct: 744 -KGEIEQERLDKVWPKL------RVLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGDGT 796
Query: 824 NDVSMIQEAHVGIGIMGKEGRQAARN-SDYAIARFKFLSKLLFV-HGHFYYIRIATLVQY 881
ND +++A VG MG G A+ SD + F S + V G Y I+ +Q+
Sbjct: 797 NDGPALKKADVGFA-MGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQF 855
Query: 882 FFYKNVCFITPQFLYQFYCLFSQQTLYDSVYLTLYNICFTSLPILIYSLLEQHV--DPHV 939
NV + F S +++ L F SL + E + P+
Sbjct: 856 QLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYG 915
Query: 940 LQNKPTLYRDISKNRL 955
++KP + R + KN L
Sbjct: 916 -RDKPLISRTMMKNIL 930
>gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo
sapiens]
Length = 1173
Score = 90.9 bits (224), Expect = 6e-18
Identities = 190/916 (20%), Positives = 343/916 (37%), Gaps = 199/916 (21%)
Query: 92 LPLFFVITVTAIKQGYEDWLRHNSDNEVNGA-----PVYVVRSGGLVKTRSKNIRVGDIV 146
L + V+ VTA + DW + + V+R+G L++ + VGDI
Sbjct: 162 LSVICVVLVTA----FNDWSKEKQFRGLQSRIEQEQKFTVIRNGQLLQVPVAALVVGDIA 217
Query: 147 RIAKDEIFPADLVLLSSDRLDGSCHVTTASLDGETNLKTHVAVPETALLQTVANLD---- 202
++ ++ PAD VL+ ++ L + +SL GE++ A + LL ++
Sbjct: 218 QVKYGDLLPADGVLIQANDLK----IDESSLTGESDHVRKSADKDPMLLSGTHVMEGSGR 273
Query: 203 TLVAVIECQQPEADLYRFMGRMIITQQMEEIVRPLGPESLLLRGARLKNTKEIFGVAVYT 262
+V + ++ +G ++ E+ + + + ++ K K+ VA+
Sbjct: 274 MVVTAVGVNSQTGIIFTLLGAG--GEEEEKKDKKGKQQDGAMESSQTKAKKQDGAVAMEM 331
Query: 263 G---------METKMALNYKSKSQKRSAVEKSMNTFLI-----------IYLVILISEAV 302
ME + + +++S ++ + + I ++IL+ V
Sbjct: 332 QPLKSAEGGEMEEREKKKANAPKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFV 391
Query: 303 ISTILKY--TWQAEEKWDEPWYNQKTEHQRNSSKILRFISDFLAFLVLYNFIIPISLYVT 360
I T + TW AE P Y Q F+ F+ + + +P L +
Sbjct: 392 IETFVVEGRTWLAE---CTPVYVQY------------FVKFFIIGVTVLVVAVPEGLPLA 436
Query: 361 VEMQKFLGSFFIGWDLDLYHEESDQKAQVNTSDLNEELGQVEYVFTDKTGTLTENEMQFR 420
V + + + + ++++ V D E +G + +DKTGTLT N M
Sbjct: 437 VTIS-------LAYSVKKMMKDNNL---VRHLDACETMGNATAICSDKTGTLTTNRMTVV 486
Query: 421 ECSINGMKYQEINGRLVPEGPTPDSSEGNLSYLSSLSHLNNLSHLTTSSSFRTSPENETE 480
+ + Y+EI P TP L L H +++ T+ PE E
Sbjct: 487 QSYLGDTHYKEIPA---PSALTP-------KILDLLVHAISINSAYTTKIL--PPEKEGA 534
Query: 481 LIKEHDLFFKAVSLCHTVQISNVQTDCTGDGPWQSNLAPSQLEYYASSPDEKALVEAAAR 540
L + Q+ N +T+C A
Sbjct: 535 LPR---------------QVGN-KTEC-------------------------------AL 547
Query: 541 IGIVFIGNSEETMEVKTLGKLERYKLLHILEFDSDRRRMSVIVQAPSGEKLLFAKGAESS 600
+G V + + V+ ++ KL + F+S R+ MS +++ P G LF+KGA
Sbjct: 548 LGFV-LDLKRDFQPVRE--QIPEDKLYKVYTFNSVRKSMSTVIRMPDGGFRLFSKGASEI 604
Query: 601 ILPKCIG-----GEI---------EKTRIHVDEFALKGLRTLCIAYRKFTSKEYEEIDKR 646
+L KC GE+ + R ++ A GLRT+CIAYR F++ + + D
Sbjct: 605 LLKKCTNILNSNGELRGFRPRDRDDMVRKIIEPMACDGLRTICIAYRDFSAGQEPDWDNE 664
Query: 647 IFEARTALQQREEKLAAVFQFIEKDLILLGATAVEDRLQDKVRETIEALRMAGIKVWVLT 706
+ DL + +ED ++ +V E I + AGI V ++T
Sbjct: 665 -------------------NEVVGDLTCIAVVGIEDPVRPEVPEAIRKCQRAGITVRMVT 705
Query: 707 GDKHETAVSVSLSCGHFHRTMNILELINQKSDSECAEQLRQLARRITEDHVIQHGLVVDG 766
GD TA +++ CG +I D C E ++ RRI +
Sbjct: 706 GDNINTARAIAAKCG----------IIQPGEDFLCLEG-KEFNRRIRNE----------- 743
Query: 767 TSLSLALREHEKLFMEVCRNCSAVLCCRMAPLQKAKVIRLI---KISPEKPITLAVGDGA 823
+ +K++ ++ + R +P K +++ I ++ + GDG
Sbjct: 744 -KGEIEQERLDKVWPKL------RVLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGDGT 796
Query: 824 NDVSMIQEAHVGIGIMGKEGRQAARN-SDYAIARFKFLSKLLFV-HGHFYYIRIATLVQY 881
ND +++A VG MG G A+ SD + F S + V G Y I+ +Q+
Sbjct: 797 NDGPALKKADVGFA-MGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQF 855
Query: 882 FFYKNVCFITPQFLYQFYCLFSQQTLYDSVYLTLYNICFTSLPILIYSLLEQHV--DPHV 939
NV + F S +++ L F SL + E + P+
Sbjct: 856 QLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYG 915
Query: 940 LQNKPTLYRDISKNRL 955
++KP + R + KN L
Sbjct: 916 -RDKPLISRTMMKNIL 930
>gi|48255951 plasma membrane calcium ATPase 2 isoform 1 [Homo
sapiens]
Length = 1243
Score = 88.6 bits (218), Expect = 3e-17
Identities = 191/932 (20%), Positives = 339/932 (36%), Gaps = 202/932 (21%)
Query: 92 LPLFFVITVTAIKQGYEDWLRHNSDNEVNGA-----PVYVVRSGGLVKTRSKNIRVGDIV 146
L + V+ VTA + DW + + VVR+G +V+ I VGDI
Sbjct: 159 LSVICVVLVTA----FNDWSKEKQFRGLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIA 214
Query: 147 RIAKDEIFPADLVLLSSD-------RLDGSCHVTTASLDGETNLK--THVAVPETALLQT 197
++ ++ PAD + + + L G S+D + L THV +L T
Sbjct: 215 QVKYGDLLPADGLFIQGNDLKIDESSLTGESDQVRKSVDKDPMLLSGTHVMEGSGRMLVT 274
Query: 198 VANLDTLVAVI----------ECQQPEADLYRFMGRMIITQQMEEIVRPLGPESLLLRGA 247
+++ +I E ++ + + + G + + L
Sbjct: 275 AVGVNSQTGIIFTLLGAGGEEEEKKDKKGVKKGDGLQLPAADGAAASNAADSANASLVNG 334
Query: 248 RLKN---------TKEIFGVAVYTGMETKMALNYKSKSQKRSAVEKSMNTFL---IIYLV 295
++++ K+ G A K A + +K++++ K + L + L
Sbjct: 335 KMQDGNVDASQSKAKQQDGAAAMEMQPLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLA 394
Query: 296 ILISEA--------VISTILKYTWQAEEKWDEPWYNQKTEHQRNSSKILRFISDFLAFLV 347
+ I +A VI +L +T +PW + T ++ F+ F
Sbjct: 395 VQIGKAGLVMSAITVIILVLYFTVDTFVVNKKPWLPECTPV---------YVQYFVKF-- 443
Query: 348 LYNFIIPISLYVTVEMQKFLGSFFIGWDLDLYHEESDQKAQVNTSDLNEELGQVEYVFTD 407
FII +++ V + + I + D V D E +G + +D
Sbjct: 444 ---FIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNL-VRHLDACETMGNATAICSD 499
Query: 408 KTGTLTENEMQFRECSINGMKYQEINGRLVPEGPTPDSSEGNLSYLSSLSHLNNLSHLTT 467
KTGTLT N M + + + Y+EI PD S N + L ++ +
Sbjct: 500 KTGTLTTNRMTVVQAYVGDVHYKEI----------PDPSSINTKTMELL-----INAIAI 544
Query: 468 SSSFRTS---PENETELIKEHDLFFKAVSLCHTVQISNVQTDCTGDGPWQSNLAPSQLEY 524
+S++ T PE E L + Q+ N +T+C G
Sbjct: 545 NSAYTTKILPPEKEGALPR---------------QVGN-KTECGLLG------------- 575
Query: 525 YASSPDEKALVEAAARIGIVFIGNSEETMEVKTLGKLERYKLLHILEFDSDRRRMSVIVQ 584
F+ + ++ E ++ KL + F+S R+ MS +++
Sbjct: 576 --------------------FVLDLKQDYE-PVRSQMPEEKLYKVYTFNSVRKSMSTVIK 614
Query: 585 APSGEKLLFAKGAESSILPKCI-----GGEI---------EKTRIHVDEFALKGLRTLCI 630
P +++KGA +L KC GE E + ++ A GLRT+C+
Sbjct: 615 LPDESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMACDGLRTICV 674
Query: 631 AYRKFTSKEYEEIDKRIFEARTALQQREEKLAAVFQFIEKDLILLGATAVEDRLQDKVRE 690
AYR F S + D I +L + +ED ++ +V E
Sbjct: 675 AYRDFPSSPEPDWDNE-------------------NDILNELTCICVVGIEDPVRPEVPE 715
Query: 691 TIEALRMAGIKVWVLTGDKHETAVSVSLSCGHFHRTMNILELINQKSDSECAEQLRQLAR 750
I + AGI V ++TGD TA ++++ CG H + L L E ++R
Sbjct: 716 AIRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCL----EGKEFNRRIRNEKG 771
Query: 751 RITEDHVIQHGLVVDGTSLSLALREHEKLFMEVCRNCSAVLCCRMAPLQKAKVIRLIKIS 810
I ++ + +K++ ++ + R +P K +++ I S
Sbjct: 772 EIEQERI-------------------DKIWPKL------RVLARSSPTDKHTLVKGIIDS 806
Query: 811 ---PEKPITLAVGDGANDVSMIQEAHVGIGIMGKEGRQAARN-SDYAIARFKFLSKLLFV 866
++ + GDG ND +++A VG MG G A+ SD + F S + V
Sbjct: 807 THTEQRQVVAVTGDGTNDGPALKKADVGFA-MGIAGTDVAKEASDIILTDDNFSSIVKAV 865
Query: 867 -HGHFYYIRIATLVQYFFYKNVCFITPQFLYQFYCLFSQQTLYDSVYLTLYNICFTSLPI 925
G Y I+ +Q+ NV + F S +++ L F SL +
Sbjct: 866 MWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLAL 925
Query: 926 LIYSLLEQHV--DPHVLQNKPTLYRDISKNRL 955
E + P+ +NKP + R + KN L
Sbjct: 926 ATEPPTETLLLRKPYG-RNKPLISRTMMKNIL 956
>gi|66932949 ATPase type 13A4 [Homo sapiens]
Length = 1196
Score = 83.2 bits (204), Expect = 1e-15
Identities = 72/308 (23%), Positives = 134/308 (43%), Gaps = 44/308 (14%)
Query: 561 LERYKLLHILEFDSDRRRMSVIVQAPSGEKLLFAKGAESSILPKCIGGEIEKTRI-HVDE 619
+E +LH F S +RM+VIVQ G++L F KGA + C + + + +
Sbjct: 590 VEGIAILHQFPFSSALQRMTVIVQEMGGDRLAFMKGAPERVASFCQPETVPTSFVSELQI 649
Query: 620 FALKGLRTLCIAYRKFTSKEYEEIDKRIFEARTALQQREEKLAAVFQFIEKDLILLGATA 679
+ +G R + +AY+K + + R + +E DLI LG
Sbjct: 650 YTTQGFRVIALAYKKLENDHHATTLTR-------------------ETVESDLIFLGLLI 690
Query: 680 VEDRLQDKVRETIEALRMAGIKVWVLTGDKHETAVSVSLSCGHFHRTMNILEL-INQKSD 738
+E+RL+++ + +E L A I+ ++TGD +TA++V+ G + ++ + N+ +
Sbjct: 691 LENRLKEETKPVLEELISARIRTVMITGDNLQTAITVARKSGMVSESQKVILIEANETTG 750
Query: 739 SECA-------EQLRQLARRITEDHVIQHGLVVD------------GTSLSLALREHEKL 779
S A E+ + + ++++ V D G S + + L
Sbjct: 751 SSSASISWTLVEEKKHIMYGNQDNYINIRDEVSDKGREGSYHFALTGKSFHVISQHFSSL 810
Query: 780 FMEVCRNCSAVLCCRMAPLQKAKVIRLIKISPEKPITLAVGDGANDVSMIQEAHVGIGIM 839
++ N + RM+P QK+ ++ + GDGAND ++ AHVGI +
Sbjct: 811 LPKILIN--GTIFARMSPGQKSSLVE--EFQKLDYFVGMCGDGANDCGALKMAHVGISLS 866
Query: 840 GKEGRQAA 847
+E A+
Sbjct: 867 EQEASVAS 874
>gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo
sapiens]
Length = 1176
Score = 82.0 bits (201), Expect = 3e-15
Identities = 129/588 (21%), Positives = 227/588 (38%), Gaps = 140/588 (23%)
Query: 393 DLNEELGQVEYVFTDKTGTLTENEMQFRECSINGMKYQEINGRLVPEGPTPDSSEGNLSY 452
D E +G + +DKTGTLT N M + IN Y+++ P P++ N+
Sbjct: 461 DACETMGNATAICSDKTGTLTMNRMTVVQAYINEKHYKKV--------PEPEAIPPNI-- 510
Query: 453 LSSLSHLNNLSHLTTSSSFRTSPENETELIKEHDLFFKAVSLCHTVQISNVQTDCTGDGP 512
LS+L T + +C
Sbjct: 511 ---------LSYLVTG----------------------------------ISVNCA---- 523
Query: 513 WQSNLAPSQLEYYASSPDEKALVEAAARIGIVFIGNSEETMEVKTLGKLERYKLLHILEF 572
+ S + P + E P A +G++ + + +V+ ++ L + F
Sbjct: 524 YTSKILPPEKE--GGLPRHVGNKTECALLGLL-LDLKRDYQDVRN--EIPEEALYKVYTF 578
Query: 573 DSDRRRMSVIVQAPSGEKLLFAKGAESSILPKCI-----GGEIEKTRIH---------VD 618
+S R+ MS +++ G +F+KGA IL KC GE + R ++
Sbjct: 579 NSVRKSMSTVLKNSDGSYRIFSKGASEIILKKCFKILSANGEAKVFRPRDRDDIVKTVIE 638
Query: 619 EFALKGLRTLCIAYRKFTSKEYE-EIDKRIFEARTALQQREEKLAAVFQFIEKDLILLGA 677
A +GLRT+C+A+R F + E E E D I L +
Sbjct: 639 PMASEGLRTICLAFRDFPAGEPEPEWDNE-------------------NDIVTGLTCIAV 679
Query: 678 TAVEDRLQDKVRETIEALRMAGIKVWVLTGDKHETAVSVSLSCGHFHRTMNILELINQKS 737
+ED ++ +V + I+ + AGI V ++TGD TA +++ CG H + L L
Sbjct: 680 VGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIATKCGILHPGEDFLCL----E 735
Query: 738 DSECAEQLRQLARRITEDHVIQHGLVVDGTSLSLALREHEKLFMEVCRNCSAVLCCRMAP 797
+ ++R I ++ + +K++ ++ + R +P
Sbjct: 736 GKDFNRRIRNEKGEIEQERI-------------------DKIWPKL------RVLARSSP 770
Query: 798 LQKAKVIRLI---KISPEKPITLAVGDGANDVSMIQEAHVGIGIMGKEGRQAARN-SDYA 853
K +++ I +S ++ + GDG ND +++A VG MG G A+ SD
Sbjct: 771 TDKHTLVKGIIDSTVSDQRQVVAVTGDGTNDGPALKKADVGFA-MGIAGTDVAKEASDII 829
Query: 854 IARFKFLSKLLFV-HGHFYYIRIATLVQYFFYKNVCFITPQF----LYQFYCLFSQQTLY 908
+ F S + V G Y I+ +Q+ NV + F + Q L + Q L+
Sbjct: 830 LTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLW 889
Query: 909 DSVYL-TLYNICFTSLPILIYSLLEQHVDPHVLQNKPTLYRDISKNRL 955
++ + TL ++ + P LL + +NKP + R + KN L
Sbjct: 890 VNLIMDTLASLALATEPPTESLLLRKPYG----RNKPLISRTMMKNIL 933
Score = 33.1 bits (74), Expect = 1.6
Identities = 17/57 (29%), Positives = 33/57 (57%), Gaps = 4/57 (7%)
Query: 126 VVRSGGLVKTRSKNIRVGDIVRIAKDEIFPADLVLLSSDRLDGSCHVTTASLDGETN 182
V+R G +++ +I VGDI ++ ++ PAD +L+ + L + +SL GE++
Sbjct: 196 VIRGGQVIQIPVADITVGDIAQVKYGDLLPADGILIQGNDL----KIDESSLTGESD 248
>gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo
sapiens]
Length = 1220
Score = 82.0 bits (201), Expect = 3e-15
Identities = 129/588 (21%), Positives = 227/588 (38%), Gaps = 140/588 (23%)
Query: 393 DLNEELGQVEYVFTDKTGTLTENEMQFRECSINGMKYQEINGRLVPEGPTPDSSEGNLSY 452
D E +G + +DKTGTLT N M + IN Y+++ P P++ N+
Sbjct: 461 DACETMGNATAICSDKTGTLTMNRMTVVQAYINEKHYKKV--------PEPEAIPPNI-- 510
Query: 453 LSSLSHLNNLSHLTTSSSFRTSPENETELIKEHDLFFKAVSLCHTVQISNVQTDCTGDGP 512
LS+L T + +C
Sbjct: 511 ---------LSYLVTG----------------------------------ISVNCA---- 523
Query: 513 WQSNLAPSQLEYYASSPDEKALVEAAARIGIVFIGNSEETMEVKTLGKLERYKLLHILEF 572
+ S + P + E P A +G++ + + +V+ ++ L + F
Sbjct: 524 YTSKILPPEKE--GGLPRHVGNKTECALLGLL-LDLKRDYQDVRN--EIPEEALYKVYTF 578
Query: 573 DSDRRRMSVIVQAPSGEKLLFAKGAESSILPKCI-----GGEIEKTRIH---------VD 618
+S R+ MS +++ G +F+KGA IL KC GE + R ++
Sbjct: 579 NSVRKSMSTVLKNSDGSYRIFSKGASEIILKKCFKILSANGEAKVFRPRDRDDIVKTVIE 638
Query: 619 EFALKGLRTLCIAYRKFTSKEYE-EIDKRIFEARTALQQREEKLAAVFQFIEKDLILLGA 677
A +GLRT+C+A+R F + E E E D I L +
Sbjct: 639 PMASEGLRTICLAFRDFPAGEPEPEWDNE-------------------NDIVTGLTCIAV 679
Query: 678 TAVEDRLQDKVRETIEALRMAGIKVWVLTGDKHETAVSVSLSCGHFHRTMNILELINQKS 737
+ED ++ +V + I+ + AGI V ++TGD TA +++ CG H + L L
Sbjct: 680 VGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIATKCGILHPGEDFLCL----E 735
Query: 738 DSECAEQLRQLARRITEDHVIQHGLVVDGTSLSLALREHEKLFMEVCRNCSAVLCCRMAP 797
+ ++R I ++ + +K++ ++ + R +P
Sbjct: 736 GKDFNRRIRNEKGEIEQERI-------------------DKIWPKL------RVLARSSP 770
Query: 798 LQKAKVIRLI---KISPEKPITLAVGDGANDVSMIQEAHVGIGIMGKEGRQAARN-SDYA 853
K +++ I +S ++ + GDG ND +++A VG MG G A+ SD
Sbjct: 771 TDKHTLVKGIIDSTVSDQRQVVAVTGDGTNDGPALKKADVGFA-MGIAGTDVAKEASDII 829
Query: 854 IARFKFLSKLLFV-HGHFYYIRIATLVQYFFYKNVCFITPQF----LYQFYCLFSQQTLY 908
+ F S + V G Y I+ +Q+ NV + F + Q L + Q L+
Sbjct: 830 LTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLW 889
Query: 909 DSVYL-TLYNICFTSLPILIYSLLEQHVDPHVLQNKPTLYRDISKNRL 955
++ + TL ++ + P LL + +NKP + R + KN L
Sbjct: 890 VNLIMDTLASLALATEPPTESLLLRKPYG----RNKPLISRTMMKNIL 933
Score = 33.1 bits (74), Expect = 1.6
Identities = 17/57 (29%), Positives = 33/57 (57%), Gaps = 4/57 (7%)
Query: 126 VVRSGGLVKTRSKNIRVGDIVRIAKDEIFPADLVLLSSDRLDGSCHVTTASLDGETN 182
V+R G +++ +I VGDI ++ ++ PAD +L+ + L + +SL GE++
Sbjct: 196 VIRGGQVIQIPVADITVGDIAQVKYGDLLPADGILIQGNDL----KIDESSLTGESD 248
>gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b
[Homo sapiens]
Length = 994
Score = 77.0 bits (188), Expect = 1e-13
Identities = 125/524 (23%), Positives = 201/524 (38%), Gaps = 110/524 (20%)
Query: 396 EELGQVEYVFTDKTGTLTENEMQFRECSINGMKYQEINGRLVPEGPTPDSSEGNLSYLSS 455
E LG + +DKTGTLT N+M + I D +G++ L+
Sbjct: 340 ETLGCTSVICSDKTGTLTTNQMSVCKMFII------------------DKVDGDICLLNE 381
Query: 456 LSHLNNLSHLTTSSSFRTSPENETELIKEHDLFFKAVSLCHTVQISNVQTDCTGDGPWQS 515
S T S++ +PE E + ++D + V+++ + C D
Sbjct: 382 FS--------ITGSTY--APEGE---VLKNDKPVRPGQYDGLVELATICALCN-DSSLDF 427
Query: 516 NLAPSQLEYYASSPDEKALVEAAARIGIVFIGNSEETMEVKTLGKLER-----------Y 564
N A E + E AL ++ + +V++L K+ER
Sbjct: 428 NEAKGVYEKVGEAT-ETALTTLVEKMNVF-------NTDVRSLSKVERANACNSVIRQLM 479
Query: 565 KLLHILEFDSDRRRMSVIV------QAPSGEKLLFAKGAESSILPKCIGGEIEKTRIHVD 618
K LEF DR+ MSV +A G K+ F KGA ++ +C + TR+
Sbjct: 480 KKEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKM-FVKGAPEGVIDRCNYVRVGTTRV--- 535
Query: 619 EFALKG-LRTLCIAYRKFTSKEYEEIDKRIFEARTALQQREEKL---AAVFQFIEKDLIL 674
L G ++ +A K + + R +REE + +A F E DL
Sbjct: 536 --PLTGPVKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETDLTF 593
Query: 675 LGATAVEDRLQDKVRETIEALRMAGIKVWVLTGDKHETAVSVSLSCGHFHRTMNILELIN 734
+G + D + +V +I+ R AGI+V ++TGD TA+++ G F + +
Sbjct: 594 VGVVGMLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVAD--- 650
Query: 735 QKSDSECAEQLRQLARRITEDHVIQHGLVVDGTSLSLALREHEKLFMEVCRNCSAVLCC- 793
R R +D L L E E CR CC
Sbjct: 651 -----------RAYTGREFDD---------------LPLAEQR----EACRRA----CCF 676
Query: 794 -RMAPLQKAKVIRLIKISPEKPITLAVGDGANDVSMIQEAHVGIGIMGKEGRQAARNSDY 852
R+ P K+K++ ++ E IT GDG ND +++A +GI MG A S+
Sbjct: 677 ARVEPSHKSKIVEYLQSYDE--ITAMTGDGVNDAPALKKAEIGIA-MGSGTAVAKTASEM 733
Query: 853 AIARFKFLSKLLFV-HGHFYYIRIATLVQYFFYKNVCFITPQFL 895
+A F + + V G Y + ++Y NV + FL
Sbjct: 734 VLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFL 777
>gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a
[Homo sapiens]
Length = 1001
Score = 77.0 bits (188), Expect = 1e-13
Identities = 125/524 (23%), Positives = 201/524 (38%), Gaps = 110/524 (20%)
Query: 396 EELGQVEYVFTDKTGTLTENEMQFRECSINGMKYQEINGRLVPEGPTPDSSEGNLSYLSS 455
E LG + +DKTGTLT N+M + I D +G++ L+
Sbjct: 340 ETLGCTSVICSDKTGTLTTNQMSVCKMFII------------------DKVDGDICLLNE 381
Query: 456 LSHLNNLSHLTTSSSFRTSPENETELIKEHDLFFKAVSLCHTVQISNVQTDCTGDGPWQS 515
S T S++ +PE E + ++D + V+++ + C D
Sbjct: 382 FS--------ITGSTY--APEGE---VLKNDKPVRPGQYDGLVELATICALCN-DSSLDF 427
Query: 516 NLAPSQLEYYASSPDEKALVEAAARIGIVFIGNSEETMEVKTLGKLER-----------Y 564
N A E + E AL ++ + +V++L K+ER
Sbjct: 428 NEAKGVYEKVGEAT-ETALTTLVEKMNVF-------NTDVRSLSKVERANACNSVIRQLM 479
Query: 565 KLLHILEFDSDRRRMSVIV------QAPSGEKLLFAKGAESSILPKCIGGEIEKTRIHVD 618
K LEF DR+ MSV +A G K+ F KGA ++ +C + TR+
Sbjct: 480 KKEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKM-FVKGAPEGVIDRCNYVRVGTTRV--- 535
Query: 619 EFALKG-LRTLCIAYRKFTSKEYEEIDKRIFEARTALQQREEKL---AAVFQFIEKDLIL 674
L G ++ +A K + + R +REE + +A F E DL
Sbjct: 536 --PLTGPVKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETDLTF 593
Query: 675 LGATAVEDRLQDKVRETIEALRMAGIKVWVLTGDKHETAVSVSLSCGHFHRTMNILELIN 734
+G + D + +V +I+ R AGI+V ++TGD TA+++ G F + +
Sbjct: 594 VGVVGMLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVAD--- 650
Query: 735 QKSDSECAEQLRQLARRITEDHVIQHGLVVDGTSLSLALREHEKLFMEVCRNCSAVLCC- 793
R R +D L L E E CR CC
Sbjct: 651 -----------RAYTGREFDD---------------LPLAEQR----EACRRA----CCF 676
Query: 794 -RMAPLQKAKVIRLIKISPEKPITLAVGDGANDVSMIQEAHVGIGIMGKEGRQAARNSDY 852
R+ P K+K++ ++ E IT GDG ND +++A +GI MG A S+
Sbjct: 677 ARVEPSHKSKIVEYLQSYDE--ITAMTGDGVNDAPALKKAEIGIA-MGSGTAVAKTASEM 733
Query: 853 AIARFKFLSKLLFV-HGHFYYIRIATLVQYFFYKNVCFITPQFL 895
+A F + + V G Y + ++Y NV + FL
Sbjct: 734 VLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFL 777
>gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens]
Length = 1039
Score = 70.5 bits (171), Expect = 9e-12
Identities = 129/603 (21%), Positives = 234/603 (38%), Gaps = 112/603 (18%)
Query: 396 EELGQVEYVFTDKTGTLTENEMQFRECSINGMKYQEINGRLVPEGPTPDSSEGNLSYLSS 455
E LG + +DKTGTLT+N M + + D+SE +
Sbjct: 380 ETLGSTSIICSDKTGTLTQNRMTVAHLWFDNQIF------------VADTSEDH------ 421
Query: 456 LSHLNNLSHLTTSSSFRTSPENETELIKEHDLFFKAVSLCHTVQISNVQTDCTGDGPWQS 515
S+ S RT K ++LC+ + P Q
Sbjct: 422 -------SNQVFDQSSRTWAS-----------LSKIITLCNRAEFK----------PGQE 453
Query: 516 NLAPSQLEYYASSPDEKALVEAAARIGIVFIGNSEETMEVKTLGKLERYKLLHILEFDSD 575
N+ P + E AL++ + V +G + ME++ +R + + + F+S
Sbjct: 454 NV-PIMKKAVIGDASETALLKFSE----VILG---DVMEIR-----KRNRKVAEIPFNST 500
Query: 576 RRRMSVI--VQAPSGEKLLFA-KGAESSILPKC----IGGE---IEKTR---IHVDEFAL 622
+ I + P G++ L KGA IL KC I GE ++K+ H L
Sbjct: 501 NKFQLSIHEMDDPHGKRFLMVMKGAPERILEKCSTIMINGEEHPLDKSTAKTFHTAYMEL 560
Query: 623 KGL--RTLCIAYRKFTSKEYEEIDKRIFEARTALQQREEKLAAVFQFIEKDLILLGATAV 680
GL R L + + E+ E +A F +L +G ++
Sbjct: 561 GGLGERVLGFCHLYLPADEFPETYSFDIDA--------------MNFPTSNLCFVGLLSM 606
Query: 681 EDRLQDKVRETIEALRMAGIKVWVLTGDKHETAVSVSLSCGHFHRTMNILELINQKSDSE 740
D + V + + R AGIKV ++TGD TA +++ S G +E I + +
Sbjct: 607 IDPPRSTVPDAVTKCRSAGIKVIMVTGDHPITAKAIAKSVGIISANSETVEDIAHRLNI- 665
Query: 741 CAEQLRQLARRITEDHVIQHGLVVDGTSLSLALREHEKLFMEVCRNCSAVLCCRMAPLQK 800
+ Q+ +R + V+ T + L E+L E+ N ++ R +P QK
Sbjct: 666 ---AVEQVNKRDAKAAVV--------TGMELKDMSSEQL-DEILANYQEIVFARTSPQQK 713
Query: 801 AKVIRLIKISPEKPITLAVGDGANDVSMIQEAHVGIGIMGKEGRQAARN-SDYAIARFKF 859
++ + + GDG ND +++A +GI MG G AA+N +D + F
Sbjct: 714 LIIVE--GCQRQDAVVAVTGDGVNDSPALKKADIGIA-MGIAGSDAAKNAADMVLLDDNF 770
Query: 860 LSKLLFV-HGHFYYIRIATLVQYFFYKNVCFITPQFLYQFYCLFSQQTLYDSVYLTLYNI 918
S + V G + + + Y KN+ + P + Y + ++ + ++
Sbjct: 771 ASIVTGVEEGRLIFDNLKKTIAYSLTKNIAELCP---FLIYIIVGLPLPIGTITILFIDL 827
Query: 919 CFTSLPILIYSLLEQHVDPHVLQNKPT-LYRDISKNRLLSIKTFLYWTILGFSHAFIFFF 977
+P + +L + + ++ KP +D N+ L++ ++L+ ++ AF+ +F
Sbjct: 828 GTDIIPSI--ALAYEKAESDIMNRKPRHKNKDRLVNQPLAVYSYLHIGLMQALGAFLVYF 885
Query: 978 GSY 980
Y
Sbjct: 886 TVY 888
Score = 37.4 bits (85), Expect = 0.085
Identities = 36/121 (29%), Positives = 53/121 (43%), Gaps = 9/121 (7%)
Query: 66 VANFYFLIIFLVQLMIDTPTS--PVTSGLPLFFVITVTAIKQGYEDWLRHN---SDNEVN 120
V F I + +Q D S V G L V+ +T I Y++ N S N++
Sbjct: 121 VGAFLCWIAYGIQYSSDKSASLNNVYLGCVLGLVVILTGIFAYYQEAKSTNIMSSFNKMI 180
Query: 121 GAPVYVVRSGGLVKTRSKNIRVGDIVRIAKDEIFPADLVLLSSDRLDGSCHVTTASLDGE 180
V+R S+ + VGDIV + + PAD+ +LSS C V +SL GE
Sbjct: 181 PQQALVIRDSEKKTIPSEQLVVGDIVEVKGGDQIPADIRVLSSQ----GCRVDNSSLTGE 236
Query: 181 T 181
+
Sbjct: 237 S 237
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.137 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,565,546
Number of Sequences: 37866
Number of extensions: 1716088
Number of successful extensions: 4797
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 51
Number of HSP's successfully gapped in prelim test: 28
Number of HSP's that attempted gapping in prelim test: 4386
Number of HSP's gapped (non-prelim): 229
length of query: 1177
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1064
effective length of database: 13,968,660
effective search space: 14862654240
effective search space used: 14862654240
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.