Guide to the Human Genome
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Search of human proteins with 62548858

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|62548858 folate hydrolase 1 isoform 2 [Homo sapiens]
         (719 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|62548858 folate hydrolase 1 isoform 2 [Homo sapiens]              1475   0.0  
gi|4758398 folate hydrolase 1 isoform 1 [Homo sapiens]               1457   0.0  
gi|4885505 N-acetylated alpha-linked acidic dipeptidase 2 [Homo ...  1007   0.0  
gi|24308545 folate hydrolase 1B [Homo sapiens]                        806   0.0  
gi|57232740 N-acetylated alpha-linked acidic dipeptidase-like 1 ...   448   e-126
gi|33589848 transferrin receptor 2 [Homo sapiens]                     242   8e-64
gi|126157508 N-acetylated alpha-linked acidic dipeptidase 2 [Hom...   200   4e-51
gi|189458819 transferrin receptor [Homo sapiens]                      194   3e-49
gi|189458817 transferrin receptor [Homo sapiens]                      194   3e-49
gi|239755481 PREDICTED: similar to Putative uncharacterized prot...    67   4e-11
gi|239744358 PREDICTED: hypothetical protein XP_002343105 [Homo ...    67   4e-11
gi|7706387 plasma glutamate carboxypeptidase [Homo sapiens]            50   7e-06
gi|65507403 SEC15-like 1 isoform a [Homo sapiens]                      37   0.049
gi|62243652 SEC15-like 1 isoform b [Homo sapiens]                      37   0.049
gi|51230412 GTPase activating Rap/RanGAP domain-like 1 isoform 2...    33   1.2  
gi|51226124 GTPase activating Rap/RanGAP domain-like 1 isoform 1...    33   1.2  
gi|153945852 G7c protein [Homo sapiens]                                32   1.6  
gi|239752780 PREDICTED: hypothetical protein [Homo sapiens]            32   2.1  
gi|239747286 PREDICTED: hypothetical protein XP_002346424 [Homo ...    32   2.1  
gi|239741110 PREDICTED: hypothetical protein XP_002342097 [Homo ...    32   2.1  
gi|23397672 homeobox D4 [Homo sapiens]                                 32   2.7  
gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]         32   2.7  
gi|110735404 protein tyrosine phosphatase, receptor type, U isof...    30   6.0  
gi|110735406 protein tyrosine phosphatase, receptor type, U isof...    30   6.0  
gi|110735402 protein tyrosine phosphatase, receptor type, U isof...    30   6.0  
gi|34013590 Rho GTPase activating protein 2 [Homo sapiens]             30   6.0  
gi|153266907 gamma-glutamyltransferase 5 isoform c [Homo sapiens]      30   7.8  
gi|153266901 gamma-glutamyltransferase 5 isoform a [Homo sapiens]      30   7.8  
gi|153266885 gamma-glutamyltransferase 5 isoform b [Homo sapiens]      30   7.8  

>gi|62548858 folate hydrolase 1 isoform 2 [Homo sapiens]
          Length = 719

 Score = 1475 bits (3818), Expect = 0.0
 Identities = 719/719 (100%), Positives = 719/719 (100%)

Query: 1   MWNLLHETDSAVATARRPRWLCAGALVLAGGFFLLGFLFGWFIKSSNEATNITPKHNMKA 60
           MWNLLHETDSAVATARRPRWLCAGALVLAGGFFLLGFLFGWFIKSSNEATNITPKHNMKA
Sbjct: 1   MWNLLHETDSAVATARRPRWLCAGALVLAGGFFLLGFLFGWFIKSSNEATNITPKHNMKA 60

Query: 61  FLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYP 120
           FLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYP
Sbjct: 61  FLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYP 120

Query: 121 NKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYA 180
           NKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYA
Sbjct: 121 NKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYA 180

Query: 181 RTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVK 240
           RTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVK
Sbjct: 181 RTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVK 240

Query: 241 SYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYY 300
           SYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYY
Sbjct: 241 SYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYY 300

Query: 301 DAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIG 360
           DAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIG
Sbjct: 301 DAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIG 360

Query: 361 TLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFAS 420
           TLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFAS
Sbjct: 361 TLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFAS 420

Query: 421 WDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKE 480
           WDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKE
Sbjct: 421 WDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKE 480

Query: 481 LKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKN 540
           LKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKN
Sbjct: 481 LKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKN 540

Query: 541 WETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDY 600
           WETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDY
Sbjct: 541 WETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDY 600

Query: 601 AVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKSKHVI 660
           AVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKSKHVI
Sbjct: 601 AVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKSKHVI 660

Query: 661 YAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 719
           YAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA
Sbjct: 661 YAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 719


>gi|4758398 folate hydrolase 1 isoform 1 [Homo sapiens]
          Length = 750

 Score = 1457 bits (3773), Expect = 0.0
 Identities = 718/750 (95%), Positives = 719/750 (95%), Gaps = 31/750 (4%)

Query: 1   MWNLLHETDSAVATARRPRWLCAGALVLAGGFFLLGFLFGWFIKSSNEATNITPKHNMKA 60
           MWNLLHETDSAVATARRPRWLCAGALVLAGGFFLLGFLFGWFIKSSNEATNITPKHNMKA
Sbjct: 1   MWNLLHETDSAVATARRPRWLCAGALVLAGGFFLLGFLFGWFIKSSNEATNITPKHNMKA 60

Query: 61  FLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYP 120
           FLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYP
Sbjct: 61  FLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYP 120

Query: 121 NKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYA 180
           NKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYA
Sbjct: 121 NKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYA 180

Query: 181 RTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVK 240
           RTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVK
Sbjct: 181 RTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVK 240

Query: 241 SYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYY 300
           SYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYY
Sbjct: 241 SYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYY 300

Query: 301 DAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIG 360
           DAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIG
Sbjct: 301 DAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIG 360

Query: 361 TLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFAS 420
           TLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFAS
Sbjct: 361 TLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFAS 420

Query: 421 WDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKE 480
           WDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKE
Sbjct: 421 WDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKE 480

Query: 481 LKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKN 540
           LKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKN
Sbjct: 481 LKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKN 540

Query: 541 WETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDY 600
           WETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDY
Sbjct: 541 WETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDY 600

Query: 601 AVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKS---- 656
           AVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKS    
Sbjct: 601 AVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKSNPIV 660

Query: 657 ---------------------------KHVIYAPSSHNKYAGESFPGIYDALFDIESKVD 689
                                      +HVIYAPSSHNKYAGESFPGIYDALFDIESKVD
Sbjct: 661 LRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVD 720

Query: 690 PSKAWGEVKRQIYVAAFTVQAAAETLSEVA 719
           PSKAWGEVKRQIYVAAFTVQAAAETLSEVA
Sbjct: 721 PSKAWGEVKRQIYVAAFTVQAAAETLSEVA 750


>gi|4885505 N-acetylated alpha-linked acidic dipeptidase 2 [Homo
           sapiens]
          Length = 740

 Score = 1007 bits (2604), Expect = 0.0
 Identities = 482/732 (65%), Positives = 581/732 (79%), Gaps = 36/732 (4%)

Query: 20  WLCAGALVLAGGFFLLGFLFGWFIKSSNEATNITPKHNMKAF--LDELKAENIKKFLYNF 77
           W+C  A + +   FL+GF+ GWFIK   E T     H    +  + E+KAENIK FL +F
Sbjct: 11  WMCLAAALAS---FLMGFMVGWFIKPLKETTTSVRYHQSIRWKLVSEMKAENIKSFLRSF 67

Query: 78  TQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNE 137
           T++PHLAGTEQNF LAK+IQ+QWK+FGLDS +L HYDVLLSYPN+T+ NYISI++E   E
Sbjct: 68  TKLPHLAGTEQNFLLAKKIQTQWKKFGLDSAKLVHYDVLLSYPNETNANYISIVDEHETE 127

Query: 138 IFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCS 197
           IF TS  EPPP GYENV++IVPP++AFS QGMPEGDLVYVNYARTEDFFKLER+M INC+
Sbjct: 128 IFKTSYLEPPPDGYENVTNIVPPYNAFSAQGMPEGDLVYVNYARTEDFFKLEREMGINCT 187

Query: 198 GKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGN 257
           GKIVIARYGK+FRGNKVKNA LAGA G+ILYSDPADYFAP V+ YP GWNLPG   QRGN
Sbjct: 188 GKIVIARYGKIFRGNKVKNAMLAGAIGIILYSDPADYFAPEVQPYPKGWNLPGTAAQRGN 247

Query: 258 ILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDS 317
           +LNLNGAGDPLTPGYPA EY +R  + E VG+P IPVHPIGY DA+ LL  +GG APPD 
Sbjct: 248 VLNLNGAGDPLTPGYPAKEYTFRLDVEEGVGIPRIPVHPIGYNDAEILLRYLGGIAPPDK 307

Query: 318 SWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGH 377
           SW+G+L V Y++GPGFTG+ S +KV+MH+++ N++TRIYNV+GT+RG+VEPDRYVILGGH
Sbjct: 308 SWKGALNVSYSIGPGFTGSDSFRKVRMHVYNINKITRIYNVVGTIRGSVEPDRYVILGGH 367

Query: 378 RDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAEEFGLLGSTEWAEE 437
           RDSWVFG IDP SG AV+ EI RSFG L  +GWRPRRTI+FASWDAEEFGLLGSTEWAEE
Sbjct: 368 RDSWVFGAIDPTSGVAVLQEIARSFGKLMSKGWRPRRTIIFASWDAEEFGLLGSTEWAEE 427

Query: 438 NSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESW 497
           N ++LQER +AYIN+DSSIEGNYTLRVDCTPL+Y LV+ LTKE+ SPD+GFE KSLYESW
Sbjct: 428 NVKILQERSIAYINSDSSIEGNYTLRVDCTPLLYQLVYKLTKEIPSPDDGFESKSLYESW 487

Query: 498 TKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSGYPLYHSVYE 557
            +K PSPE   +PRI+KLGSG+DFE +FQRLGIASGRARYTKN +T+K+S YP+YH++YE
Sbjct: 488 LEKDPSPENKNLPRINKLGSGSDFEAYFQRLGIASGRARYTKNKKTDKYSSYPVYHTIYE 547

Query: 558 TYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMK 617
           T+ELVEKFYDP FK  L+VAQ+RG +V+EL +S ++PF+ +DYA  L+ YA  IY++S K
Sbjct: 548 TFELVEKFYDPTFKKQLSVAQLRGALVYELVDSKIIPFNIQDYAEALKNYAASIYNLSKK 607

Query: 618 HPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKS--------------------- 656
           H Q++  + VSFDSLFSAVKNF+E AS F +RL   D +                     
Sbjct: 608 HDQQLTDHGVSFDSLFSAVKNFSEAASDFHKRLIQVDLNNPIAVRMMNDQLMLLERAFID 667

Query: 657 ----------KHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAF 706
                     +H+I+APSSHNKYAGESFPGIYDA+FDIE+K +   AW EVK+ I +AAF
Sbjct: 668 PLGLPGKLFYRHIIFAPSSHNKYAGESFPGIYDAIFDIENKANSRLAWKEVKKHISIAAF 727

Query: 707 TVQAAAETLSEV 718
           T+QAAA TL EV
Sbjct: 728 TIQAAAGTLKEV 739


>gi|24308545 folate hydrolase 1B [Homo sapiens]
          Length = 442

 Score =  806 bits (2081), Expect = 0.0
 Identities = 402/442 (90%), Positives = 408/442 (92%), Gaps = 31/442 (7%)

Query: 309 MGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEP 368
           MGGSAPPDSSWRGSLKV YNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEP
Sbjct: 1   MGGSAPPDSSWRGSLKVSYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEP 60

Query: 369 DRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAEEFGL 428
           DRYVILGGHRDSWVFGGIDPQSGAAVVHE VRSFGTLKKEGWRPRRTILFASWDAEEFGL
Sbjct: 61  DRYVILGGHRDSWVFGGIDPQSGAAVVHETVRSFGTLKKEGWRPRRTILFASWDAEEFGL 120

Query: 429 LGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGF 488
           LGSTEWAE+NSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLV+NLTKELKSPDEGF
Sbjct: 121 LGSTEWAEDNSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVYNLTKELKSPDEGF 180

Query: 489 EGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSG 548
           EGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSG
Sbjct: 181 EGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSG 240

Query: 549 YPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYA 608
           YPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYA
Sbjct: 241 YPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYA 300

Query: 609 DKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKS------------ 656
           DKIY+ISMKHPQEMKTYS+SFDSLFSAVKNFTEIASKFSERLQDFDKS            
Sbjct: 301 DKIYNISMKHPQEMKTYSLSFDSLFSAVKNFTEIASKFSERLQDFDKSNPILLRMMNDQL 360

Query: 657 -------------------KHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEV 697
                              +HVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWG+V
Sbjct: 361 MFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGDV 420

Query: 698 KRQIYVAAFTVQAAAETLSEVA 719
           KRQI VAAFTVQAAAETLSEVA
Sbjct: 421 KRQISVAAFTVQAAAETLSEVA 442


>gi|57232740 N-acetylated alpha-linked acidic dipeptidase-like 1
           [Homo sapiens]
          Length = 740

 Score =  448 bits (1152), Expect = e-126
 Identities = 271/743 (36%), Positives = 403/743 (54%), Gaps = 63/743 (8%)

Query: 24  GALVLAGGFFLLGFLFGWFI---KSSNEATNITPKHNMKAFLDELKAENIKKFLYNFTQI 80
           GA  L G    LG + G F    K+++ A        ++  + +L A  I++ L   ++ 
Sbjct: 12  GAAALLG----LGIILGHFAIPKKANSLAPQDLDLEILETVMGQLDAHRIRENLRELSRE 67

Query: 81  PHLAGTEQNFQLAKQIQSQWK--EFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEI 138
           PHLA + ++  L + +  +WK  E GLDS E + Y+VLLS+P++  PN + I+   G  I
Sbjct: 68  PHLASSPRDEDLVQLLLQRWKDPESGLDSAEASTYEVLLSFPSQEQPNVVDIVGPTGGII 127

Query: 139 FNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSG 198
            +    E    G +   D+V P++A++P G P+G LVY N    EDF +L+    I   G
Sbjct: 128 HSCHRTEENVTGEQGGPDVVQPYAAYAPSGTPQGLLVYANRGAEEDFKELQTQ-GIKLEG 186

Query: 199 KIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADY---FAPGVKSYPDGWNLPGGGVQR 255
            I + RYG V RG K  NA   G  GV++Y+DPAD     +   +++P+ W LP  GV+R
Sbjct: 187 TIALTRYGGVGRGAKAVNAAKHGVAGVLVYTDPADINDGLSSPDETFPNSWYLPPSGVER 246

Query: 256 GNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPP 315
           G+       GDPLTP  PA   ++R  +A   G P IP  PIG+ DA+ LL  + G+  P
Sbjct: 247 GSYYEY--FGDPLTPYLPAVPSSFRVDLANVSGFPPIPTQPIGFQDARDLLCNLNGTLAP 304

Query: 316 DSSWRGSLKVPYNVGPGFT--GNF-STQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYV 372
            ++W+G+L   Y +GPGF   G+F +  +V + +++  E+    NV+G +RGAVEPDRYV
Sbjct: 305 -ATWQGALGCHYRLGPGFRPDGDFPADSQVNVSVYNRLELRNSSNVLGIIRGAVEPDRYV 363

Query: 373 ILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEG-WRPRRTILFASWDAEEFGLLGS 431
           + G HRDSWV G +DP SG AV+ E+ R  GTL K+G WRPRR+I+FASW AEEFGL+GS
Sbjct: 364 LYGNHRDSWVHGAVDPSSGTAVLLELSRVLGTLLKKGTWRPRRSIVFASWGAEEFGLIGS 423

Query: 432 TEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGK 491
           TE+ EE    LQER VAYIN D S+  N TLRV  TP + S+V + TKE++SP  G    
Sbjct: 424 TEFTEEFFNKLQERTVAYINVDISVFANATLRVQGTPPVQSVVFSATKEIRSPGPG--DL 481

Query: 492 SLYESWTK--KSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSGY 549
           S+Y++W +     SP +  +P +  LG+G+D+  F   LGI+S    YT +        Y
Sbjct: 482 SIYDNWIRYFNRSSPVYGLVPSLGSLGAGSDYAPFVHFLGISSMDIAYTYDRSKTSARIY 541

Query: 550 PLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYAD 609
           P YH+ ++T++ V+KF DP F  H  VA+  G ++  L++S  LP    DY+  LR +  
Sbjct: 542 PTYHTAFDTFDYVDKFLDPGFSSHQAVARTAGSVILRLSDSFFLPLKVSDYSETLRSF-- 599

Query: 610 KIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKS------------- 656
            + +        ++ +S+S   L +AV+ F   A+   +R+    K              
Sbjct: 600 -LQAAQQDLGALLEQHSISLGPLVTAVEKFEAEAAALGQRISTLQKGSPDPLQVRMLNDQ 658

Query: 657 --------------------KHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGE 696
                                HV++AP + +     +FPG+ +A          S+AW E
Sbjct: 659 LMLLERTFLNPRAFPEERYYSHVLWAPRTGSVV---TFPGLSNACSRARDTASGSEAWAE 715

Query: 697 VKRQIYVAAFTVQAAAETLSEVA 719
           V+RQ+ +    ++ AA TL  VA
Sbjct: 716 VQRQLSIVVTALEGAAATLRPVA 738


>gi|33589848 transferrin receptor 2 [Homo sapiens]
          Length = 801

 Score =  242 bits (618), Expect = 8e-64
 Identities = 185/661 (27%), Positives = 312/661 (47%), Gaps = 64/661 (9%)

Query: 11  AVATARRPRWLCAGALVLAGGFFLLGFLF--------GWFIKSSNEATNITPK---HNMK 59
           A A  R   +L   AL++  G FLLG++         G  +   +E  N  P    H  +
Sbjct: 75  AAAGRRAAPYLVLTALLIFTGAFLLGYVAFRGSCQACGDSVLVVSEDVNYEPDLDFHQGR 134

Query: 60  AFLDELKAE--------NIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELA 111
            +  +L+A          ++  +   +    +AG+     L + I++      LD V   
Sbjct: 135 LYWSDLQAMFLQFLGEGRLEDTIRQTSLRERVAGSAGMAALTQDIRAALSRQKLDHVWTD 194

Query: 112 HYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPE 171
            + V L +P+  HPN +  ++E G       L +P         D+  P+SA    G   
Sbjct: 195 THYVGLQFPDPAHPNTLHWVDEAGKVGEQLPLEDP---------DVYCPYSAI---GNVT 242

Query: 172 GDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDP 231
           G+LVY +Y R ED   L R   ++  G++++ R G +    KV NAQ  GA+GV++Y +P
Sbjct: 243 GELVYAHYGRPEDLQDL-RARGVDPVGRLLLVRVGVISFAQKVTNAQDFGAQGVLIYPEP 301

Query: 232 ADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPS 291
           AD+     K          G V  G        GDP TPG+P+        +A + GLPS
Sbjct: 302 ADFSQDPPKPSLSSQQAVYGHVHLGT-------GDPYTPGFPSFNQTQFPPVASS-GLPS 353

Query: 292 IPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLK-VPYNVGPGFTGNFSTQKVKMHIHSTN 350
           IP  PI    A +LL K+ G   P   W+GSL   PY++GPG        ++++ +++  
Sbjct: 354 IPAQPISADIASRLLRKLKGPVAPQE-WQGSLLGSPYHLGPG-------PRLRLVVNNHR 405

Query: 351 EVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGW 410
             T I N+ G + G  EPD YV++G  RD+W  G      G A++ E+VR+F ++   G+
Sbjct: 406 TSTPINNIFGCIEGRSEPDHYVVIGAQRDAWGPGAAKSAVGTAILLELVRTFSSMVSNGF 465

Query: 411 RPRRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLM 470
           RPRR++LF SWD  +FG +GSTEW E    +L  + V Y++ D+++ G+       +PL+
Sbjct: 466 RPRRSLLFISWDGGDFGSVGSTEWLEGYLSVLHLKAVVYVSLDNAVLGDDKFHAKTSPLL 525

Query: 471 YSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGI 530
            SL+ ++ K++ SP+    G++LYE     +PS +   +  +    S   F  F   +G+
Sbjct: 526 TSLIESVLKQVDSPNH--SGQTLYEQVVFTNPSWDAEVIRPLPMDSSAYSFTAF---VGV 580

Query: 531 ASGRARYTKNWETNKFSGYPLYHSVYETYELVEKFYDPMF-KYHLTVAQVRGGMVFELAN 589
            +    + ++ +      YP  H+  +TYE + K            VAQ+ G ++  L++
Sbjct: 581 PAVEFSFMEDDQ-----AYPFLHTKEDTYENLHKVLQGRLPAVAQAVAQLAGQLLIRLSH 635

Query: 590 SIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSER 649
             +LP D   Y  V+ ++   +   S     ++K   ++   ++SA  ++   A K  + 
Sbjct: 636 DRLLPLDFGRYGDVVLRHIGNLNEFS----GDLKARGLTLQWVYSARGDYIRAAEKLRQE 691

Query: 650 L 650
           +
Sbjct: 692 I 692


>gi|126157508 N-acetylated alpha-linked acidic dipeptidase 2 [Homo
           sapiens]
          Length = 795

 Score =  200 bits (508), Expect = 4e-51
 Identities = 164/608 (26%), Positives = 280/608 (46%), Gaps = 67/608 (11%)

Query: 4   LLHETDSAVATARRPRWLCAGALVLAGGFFLLGFLFGWFIK----SSNEATNITPKHNMK 59
           + H T SA  + R         L  A   F+ G L G+++     S   ++        +
Sbjct: 107 ITHYTRSAPKSNRCNFCHVLKILCTATILFIFGILIGYYVHTNCPSDAPSSGTVDPQLYQ 166

Query: 60  AFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSY 119
             L  ++AE+IKK   N  Q   L   E + +++K+I++QW   GL+ V+  +Y VLL  
Sbjct: 167 EILKTIQAEDIKKSFRNLVQ---LYKNEDDMEISKKIKTQWTSLGLEDVQFVNYSVLLDL 223

Query: 120 PNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVS-DIVPPFSAFSPQGMPEGDLVYVN 178
           P    P+  ++      + F+ +         ++ S D++  ++A+S +G  + +++ V+
Sbjct: 224 PG---PSPSTVTLSSSGQCFHPNGQPCSEEARKDSSQDLLYSYAAYSAKGTLKAEVIDVS 280

Query: 179 YARTEDFFKLERDMKI-NCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAP 237
           Y   +D   L+R  KI N + +I + + GK+    K+ + + AG  GV+LY DP D    
Sbjct: 281 YGMADD---LKRIRKIKNVTNQIALLKLGKLPLLYKLSSLEKAGFGGVLLYIDPCD-LPK 336

Query: 238 GVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPI 297
            V    D +           +++LN  GDP TPGYP+ + ++R+  +    L S+ V PI
Sbjct: 337 TVNPSHDTF-----------MVSLNPGGDPSTPGYPSVDESFRQSRSN---LTSLLVQPI 382

Query: 298 GYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYN 357
                 KL+         ++    SL++P N           + V M + +  ++  + N
Sbjct: 383 SAPLVAKLISSPKARTKNEAC--SSLELPNN---------EIRVVSMQVQTVTKLKTVTN 431

Query: 358 VIGTLRGAVEPDRYVILGGHRDS-WVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTI 416
           V+G + G   PDRY+I+G H  +   + G +  S  A++   +R+  +  K GWRP RTI
Sbjct: 432 VVGFVMGLTSPDRYIIVGSHHHTAHSYNGQEWASSTAIITAFIRALMSKVKRGWRPDRTI 491

Query: 417 LFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHN 476
           +F SW    FG +GS EW E+  ++LQ+  VAYI+  S I GN +L    +P +  LV  
Sbjct: 492 VFCSWGGTAFGNIGSYEWGEDFKKVLQKNVVAYISLHSPIRGNSSLYPVASPSLQQLVVE 551

Query: 477 LTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRAR 536
                              + T+++  PE      IS +    D + F   LG+   +  
Sbjct: 552 KNN---------------FNCTRRAQCPE----TNISSIQIQGDADYFINHLGVPIVQFA 592

Query: 537 Y--TKNWETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLP 594
           Y   K  E   F    L  + + T     +  DP F  H T+ ++ G ++ ++AN  VLP
Sbjct: 593 YEDIKTLEGPSF----LSEARFSTRATKIEEMDPSFNLHETITKLSGEVILQIANEPVLP 648

Query: 595 FDCRDYAV 602
           F+  D A+
Sbjct: 649 FNALDIAL 656


>gi|189458819 transferrin receptor [Homo sapiens]
          Length = 760

 Score =  194 bits (492), Expect = 3e-49
 Identities = 173/700 (24%), Positives = 306/700 (43%), Gaps = 115/700 (16%)

Query: 55  KHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYD 114
           K  +   LD        K L   + +P  AG++++  LA  +++Q++EF L  V    + 
Sbjct: 128 KRKLSEKLDSTDFTGTIKLLNENSYVPREAGSQKDENLALYVENQFREFKLSKVWRDQHF 187

Query: 115 VLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDL 174
           V +   +    N + I++++G  ++        P GY           A+S      G L
Sbjct: 188 VKIQVKDSAQ-NSVIIVDKNGRLVYLVE----NPGGYV----------AYSKAATVTGKL 232

Query: 175 VYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADY 234
           V+ N+   +DF     D+    +G IVI R GK+    KV NA+   A GV++Y D   +
Sbjct: 233 VHANFGTKKDF----EDLYTPVNGSIVIVRAGKITFAEKVANAESLNAIGVLIYMDQTKF 288

Query: 235 FAPGVK-SYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIP 293
                + S+    +L              G GDP TPG+P+  +  +   + + GLP+IP
Sbjct: 289 PIVNAELSFFGHAHL--------------GTGDPYTPGFPSFNHT-QFPPSRSSGLPNIP 333

Query: 294 VHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVT 353
           V  I    A+KL   M G  P D     + ++  +          ++ VK+ + +  +  
Sbjct: 334 VQTISRAAAEKLFGNMEGDCPSDWKTDSTCRMVTS---------ESKNVKLTVSNVLKEI 384

Query: 354 RIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLK-KEGWRP 412
           +I N+ G ++G VEPD YV++G  RD+W  G      G A++ ++ + F  +  K+G++P
Sbjct: 385 KILNIFGVIKGFVEPDHYVVVGAQRDAWGPGAAKSGVGTALLLKLAQMFSDMVLKDGFQP 444

Query: 413 RRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYS 472
            R+I+FASW A +FG +G+TEW E     L  +   YIN D ++ G    +V  +PL+Y+
Sbjct: 445 SRSIIFASWSAGDFGSVGATEWLEGYLSSLHLKAFTYINLDKAVLGTSNFKVSASPLLYT 504

Query: 473 LVHNLTKELKSPDEGFEGKSLYE--SWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGI 530
           L+    + +K P     G+ LY+  +W  K           + KL   N    F    GI
Sbjct: 505 LIEKTMQNVKHP---VTGQFLYQDSNWASK-----------VEKLTLDNAAFPFLAYSGI 550

Query: 531 ASGRARYTKNWETNKFSGYPLYHSVYETY-ELVEKFYDPMFKYHLTVAQVRGGMVFELAN 589
            +    + ++      + YP   +  +TY EL+E+  + + K     A+V G  V +L +
Sbjct: 551 PAVSFCFCED------TDYPYLGTTMDTYKELIERIPE-LNKVARAAAEVAGQFVIKLTH 603

Query: 590 SIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSER 649
            + L  D   Y   L  +   +     ++  ++K   +S   L+SA  +F    S+ +  
Sbjct: 604 DVELNLDYERYNSQLLSFVRDL----NQYRADIKEMGLSLQWLYSARGDFFRATSRLTTD 659

Query: 650 LQDFDKS-------------------------------KHVIYAPSSHNKYAGESFPGIY 678
             + +K+                               +HV +   SH      + P + 
Sbjct: 660 FGNAEKTDRFVMKKLNDRVMRVEYHFLSPYVSPKESPFRHVFWGSGSH------TLPAL- 712

Query: 679 DALFDIESKVDPSKAWGEV--KRQIYVAAFTVQAAAETLS 716
             L +++ +   + A+ E   + Q+ +A +T+Q AA  LS
Sbjct: 713 --LENLKLRKQNNGAFNETLFRNQLALATWTIQGAANALS 750


>gi|189458817 transferrin receptor [Homo sapiens]
          Length = 760

 Score =  194 bits (492), Expect = 3e-49
 Identities = 173/700 (24%), Positives = 306/700 (43%), Gaps = 115/700 (16%)

Query: 55  KHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYD 114
           K  +   LD        K L   + +P  AG++++  LA  +++Q++EF L  V    + 
Sbjct: 128 KRKLSEKLDSTDFTGTIKLLNENSYVPREAGSQKDENLALYVENQFREFKLSKVWRDQHF 187

Query: 115 VLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDL 174
           V +   +    N + I++++G  ++        P GY           A+S      G L
Sbjct: 188 VKIQVKDSAQ-NSVIIVDKNGRLVYLVE----NPGGYV----------AYSKAATVTGKL 232

Query: 175 VYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADY 234
           V+ N+   +DF     D+    +G IVI R GK+    KV NA+   A GV++Y D   +
Sbjct: 233 VHANFGTKKDF----EDLYTPVNGSIVIVRAGKITFAEKVANAESLNAIGVLIYMDQTKF 288

Query: 235 FAPGVK-SYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIP 293
                + S+    +L              G GDP TPG+P+  +  +   + + GLP+IP
Sbjct: 289 PIVNAELSFFGHAHL--------------GTGDPYTPGFPSFNHT-QFPPSRSSGLPNIP 333

Query: 294 VHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVT 353
           V  I    A+KL   M G  P D     + ++  +          ++ VK+ + +  +  
Sbjct: 334 VQTISRAAAEKLFGNMEGDCPSDWKTDSTCRMVTS---------ESKNVKLTVSNVLKEI 384

Query: 354 RIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLK-KEGWRP 412
           +I N+ G ++G VEPD YV++G  RD+W  G      G A++ ++ + F  +  K+G++P
Sbjct: 385 KILNIFGVIKGFVEPDHYVVVGAQRDAWGPGAAKSGVGTALLLKLAQMFSDMVLKDGFQP 444

Query: 413 RRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYS 472
            R+I+FASW A +FG +G+TEW E     L  +   YIN D ++ G    +V  +PL+Y+
Sbjct: 445 SRSIIFASWSAGDFGSVGATEWLEGYLSSLHLKAFTYINLDKAVLGTSNFKVSASPLLYT 504

Query: 473 LVHNLTKELKSPDEGFEGKSLYE--SWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGI 530
           L+    + +K P     G+ LY+  +W  K           + KL   N    F    GI
Sbjct: 505 LIEKTMQNVKHP---VTGQFLYQDSNWASK-----------VEKLTLDNAAFPFLAYSGI 550

Query: 531 ASGRARYTKNWETNKFSGYPLYHSVYETY-ELVEKFYDPMFKYHLTVAQVRGGMVFELAN 589
            +    + ++      + YP   +  +TY EL+E+  + + K     A+V G  V +L +
Sbjct: 551 PAVSFCFCED------TDYPYLGTTMDTYKELIERIPE-LNKVARAAAEVAGQFVIKLTH 603

Query: 590 SIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSER 649
            + L  D   Y   L  +   +     ++  ++K   +S   L+SA  +F    S+ +  
Sbjct: 604 DVELNLDYERYNSQLLSFVRDL----NQYRADIKEMGLSLQWLYSARGDFFRATSRLTTD 659

Query: 650 LQDFDKS-------------------------------KHVIYAPSSHNKYAGESFPGIY 678
             + +K+                               +HV +   SH      + P + 
Sbjct: 660 FGNAEKTDRFVMKKLNDRVMRVEYHFLSPYVSPKESPFRHVFWGSGSH------TLPAL- 712

Query: 679 DALFDIESKVDPSKAWGEV--KRQIYVAAFTVQAAAETLS 716
             L +++ +   + A+ E   + Q+ +A +T+Q AA  LS
Sbjct: 713 --LENLKLRKQNNGAFNETLFRNQLALATWTIQGAANALS 750


>gi|239755481 PREDICTED: similar to Putative uncharacterized protein
           ENSP00000334305 [Homo sapiens]
          Length = 771

 Score = 67.4 bits (163), Expect = 4e-11
 Identities = 31/44 (70%), Positives = 37/44 (84%)

Query: 264 AGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLE 307
           + +P    + ++EYAYR GIAEAVGLPSIPVHPIGYYDA+KLLE
Sbjct: 462 SSNPNQDDFHSSEYAYRCGIAEAVGLPSIPVHPIGYYDAEKLLE 505


>gi|239744358 PREDICTED: hypothetical protein XP_002343105 [Homo
           sapiens]
          Length = 767

 Score = 67.4 bits (163), Expect = 4e-11
 Identities = 31/44 (70%), Positives = 37/44 (84%)

Query: 264 AGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLE 307
           + +P    + ++EYAYR GIAEAVGLPSIPVHPIGYYDA+KLLE
Sbjct: 458 SSNPNQDDFHSSEYAYRCGIAEAVGLPSIPVHPIGYYDAEKLLE 501


>gi|7706387 plasma glutamate carboxypeptidase [Homo sapiens]
          Length = 472

 Score = 50.1 bits (118), Expect = 7e-06
 Identities = 27/84 (32%), Positives = 45/84 (53%), Gaps = 5/84 (5%)

Query: 353 TRIYNVIGTLRGAVEPDRYVILGGHRDSWVF--GGIDPQSGAAVVHEIVRSFGTLKKEGW 410
           T  +N +  + G+  P++ V++ GH DSW    G +D   GA +  E   +   +K  G 
Sbjct: 266 TDSFNTVAEITGSKYPEQVVLVSGHLDSWDVGQGAMDDGGGAFISWE---ALSLIKDLGL 322

Query: 411 RPRRTILFASWDAEEFGLLGSTEW 434
           RP+RT+    W AEE G +G+ ++
Sbjct: 323 RPKRTLRLVLWTAEEQGGVGAFQY 346


>gi|65507403 SEC15-like 1 isoform a [Homo sapiens]
          Length = 804

 Score = 37.4 bits (85), Expect = 0.049
 Identities = 23/78 (29%), Positives = 37/78 (47%), Gaps = 1/78 (1%)

Query: 552 YHSVYETYELVEKFYDP-MFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADK 610
           Y+S  +T E +E  Y P + +Y      +            +   D +D+   +RK++DK
Sbjct: 154 YYSALKTMEQLENVYFPWVSQYRFCQLMIENLPKLREDIKEISMSDLKDFLESIRKHSDK 213

Query: 611 IYSISMKHPQEMKTYSVS 628
           I   +MK  Q  KT+SVS
Sbjct: 214 IGETAMKQAQHQKTFSVS 231


>gi|62243652 SEC15-like 1 isoform b [Homo sapiens]
          Length = 799

 Score = 37.4 bits (85), Expect = 0.049
 Identities = 23/78 (29%), Positives = 37/78 (47%), Gaps = 1/78 (1%)

Query: 552 YHSVYETYELVEKFYDP-MFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADK 610
           Y+S  +T E +E  Y P + +Y      +            +   D +D+   +RK++DK
Sbjct: 149 YYSALKTMEQLENVYFPWVSQYRFCQLMIENLPKLREDIKEISMSDLKDFLESIRKHSDK 208

Query: 611 IYSISMKHPQEMKTYSVS 628
           I   +MK  Q  KT+SVS
Sbjct: 209 IGETAMKQAQHQKTFSVS 226


>gi|51230412 GTPase activating Rap/RanGAP domain-like 1 isoform 2
           [Homo sapiens]
          Length = 2083

 Score = 32.7 bits (73), Expect = 1.2
 Identities = 16/43 (37%), Positives = 21/43 (48%)

Query: 120 PNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFS 162
           P  T   + S   E GNE+F     E P P   + SDI+ PF+
Sbjct: 764 PRSTRVRHFSQSEETGNEVFGALNEEQPLPRSSSTSDILEPFT 806


>gi|51226124 GTPase activating Rap/RanGAP domain-like 1 isoform 1
           [Homo sapiens]
          Length = 2036

 Score = 32.7 bits (73), Expect = 1.2
 Identities = 16/43 (37%), Positives = 21/43 (48%)

Query: 120 PNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFS 162
           P  T   + S   E GNE+F     E P P   + SDI+ PF+
Sbjct: 764 PRSTRVRHFSQSEETGNEVFGALNEEQPLPRSSSTSDILEPFT 806


>gi|153945852 G7c protein [Homo sapiens]
          Length = 891

 Score = 32.3 bits (72), Expect = 1.6
 Identities = 15/52 (28%), Positives = 26/52 (50%), Gaps = 2/52 (3%)

Query: 249 PGGGVQRGNILNLNGAGDPLTPGYPANEYAY--RRGIAEAVGLPSIPVHPIG 298
           P  G+Q   ++ + G G    PG P   +++   RG+ E   L  +P+ P+G
Sbjct: 625 PVAGLQTQLLVEVTGLGSRANPGDPQPHFSHVILRGVPEGAELGQVPLEPVG 676


>gi|239752780 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 290

 Score = 32.0 bits (71), Expect = 2.1
 Identities = 25/74 (33%), Positives = 33/74 (44%), Gaps = 4/74 (5%)

Query: 321 GSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDS 380
           GS K P  +GP  TG   + ++ +   S   V R    +G   GAV P   V+L G   S
Sbjct: 46  GSSKSP--LGPPLTGTSGSSRIVVRKVSGVGVCREATSVGP--GAVVPRGRVLLSGMSGS 101

Query: 381 WVFGGIDPQSGAAV 394
           WV  G+    G  V
Sbjct: 102 WVVAGLGRALGREV 115


>gi|239747286 PREDICTED: hypothetical protein XP_002346424 [Homo
           sapiens]
          Length = 290

 Score = 32.0 bits (71), Expect = 2.1
 Identities = 25/74 (33%), Positives = 33/74 (44%), Gaps = 4/74 (5%)

Query: 321 GSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDS 380
           GS K P  +GP  TG   + ++ +   S   V R    +G   GAV P   V+L G   S
Sbjct: 46  GSSKSP--LGPPLTGTSGSSRIVVRKVSGVGVCREATSVGP--GAVVPRGRVLLSGMSGS 101

Query: 381 WVFGGIDPQSGAAV 394
           WV  G+    G  V
Sbjct: 102 WVVAGLGRALGREV 115


>gi|239741110 PREDICTED: hypothetical protein XP_002342097 [Homo
           sapiens]
          Length = 290

 Score = 32.0 bits (71), Expect = 2.1
 Identities = 25/74 (33%), Positives = 33/74 (44%), Gaps = 4/74 (5%)

Query: 321 GSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDS 380
           GS K P  +GP  TG   + ++ +   S   V R    +G   GAV P   V+L G   S
Sbjct: 46  GSSKSP--LGPPLTGTSGSSRIVVRKVSGVGVCREATSVGP--GAVVPRGRVLLSGMSGS 101

Query: 381 WVFGGIDPQSGAAV 394
           WV  G+    G  V
Sbjct: 102 WVVAGLGRALGREV 115


>gi|23397672 homeobox D4 [Homo sapiens]
          Length = 255

 Score = 31.6 bits (70), Expect = 2.7
 Identities = 32/119 (26%), Positives = 42/119 (35%), Gaps = 16/119 (13%)

Query: 232 ADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPS 291
           AD+  PG+   PD    P GG   G    L   G    PG P   YA     A     P+
Sbjct: 44  ADFQPPGLYPRPDFGEQPFGGSGPGPGSALPARGHGQEPGGPGGHYA-----APGEPCPA 98

Query: 292 IPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTN 350
            P  P       +   +     PP  +   +LK P  V P           K+H++S N
Sbjct: 99  PPAPPPAPLPGARAYSQSDPKQPPSGT---ALKQPAVVYPWMK--------KVHVNSVN 146


>gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]
          Length = 1690

 Score = 31.6 bits (70), Expect = 2.7
 Identities = 21/57 (36%), Positives = 24/57 (42%), Gaps = 5/57 (8%)

Query: 237 PGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIP 293
           PG+  YP     PGG  Q G++     AG    PG P      R G     GLP IP
Sbjct: 839 PGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPG-----RPGAHGPPGLPGIP 890


>gi|110735404 protein tyrosine phosphatase, receptor type, U isoform 1
            precursor [Homo sapiens]
          Length = 1436

 Score = 30.4 bits (67), Expect = 6.0
 Identities = 20/72 (27%), Positives = 33/72 (45%), Gaps = 5/72 (6%)

Query: 293  PVHPIGYYDAQKL--LEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTN 350
            P H + Y+    L  + ++  S PPD+   G + +  + G G TG +    V + +    
Sbjct: 1042 PEHGVPYHATGLLAFIRRVKASTPPDA---GPIVIHCSAGTGRTGCYIVLDVMLDMAECE 1098

Query: 351  EVTRIYNVIGTL 362
             V  IYN + TL
Sbjct: 1099 GVVDIYNCVKTL 1110


>gi|110735406 protein tyrosine phosphatase, receptor type, U isoform 2
            precursor [Homo sapiens]
          Length = 1442

 Score = 30.4 bits (67), Expect = 6.0
 Identities = 20/72 (27%), Positives = 33/72 (45%), Gaps = 5/72 (6%)

Query: 293  PVHPIGYYDAQKL--LEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTN 350
            P H + Y+    L  + ++  S PPD+   G + +  + G G TG +    V + +    
Sbjct: 1048 PEHGVPYHATGLLAFIRRVKASTPPDA---GPIVIHCSAGTGRTGCYIVLDVMLDMAECE 1104

Query: 351  EVTRIYNVIGTL 362
             V  IYN + TL
Sbjct: 1105 GVVDIYNCVKTL 1116


>gi|110735402 protein tyrosine phosphatase, receptor type, U isoform 3
            precursor [Homo sapiens]
          Length = 1446

 Score = 30.4 bits (67), Expect = 6.0
 Identities = 20/72 (27%), Positives = 33/72 (45%), Gaps = 5/72 (6%)

Query: 293  PVHPIGYYDAQKL--LEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTN 350
            P H + Y+    L  + ++  S PPD+   G + +  + G G TG +    V + +    
Sbjct: 1052 PEHGVPYHATGLLAFIRRVKASTPPDA---GPIVIHCSAGTGRTGCYIVLDVMLDMAECE 1108

Query: 351  EVTRIYNVIGTL 362
             V  IYN + TL
Sbjct: 1109 GVVDIYNCVKTL 1120


>gi|34013590 Rho GTPase activating protein 2 [Homo sapiens]
          Length = 698

 Score = 30.4 bits (67), Expect = 6.0
 Identities = 31/127 (24%), Positives = 52/127 (40%), Gaps = 15/127 (11%)

Query: 243 PDGWNLPGGGVQ-----RGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPI 297
           P+G   P GG+Q         +  +  G+P  PG PA+  +   G A AV   + P  P 
Sbjct: 354 PEGPTSPRGGLQCAVGWGSEEVTRDSQGEPGGPGLPAHRTSSLDGAAVAVLSRTAPTGPG 413

Query: 298 GYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYN 357
                 K ++ +        SW+ S + P ++     G  S+ +V +     N    + N
Sbjct: 414 SRCSPGKKVQTL-------PSWKSSFRQPRSLSGSPKGGGSSLEVPIISSGGN---WLMN 463

Query: 358 VIGTLRG 364
            + +LRG
Sbjct: 464 GLSSLRG 470


>gi|153266907 gamma-glutamyltransferase 5 isoform c [Homo sapiens]
          Length = 554

 Score = 30.0 bits (66), Expect = 7.8
 Identities = 11/39 (28%), Positives = 24/39 (61%)

Query: 109 ELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPP 147
           +L+HY +  ++ + T  +++S++ EDG+ +  TS    P
Sbjct: 340 QLSHYSLAEAWGHGTGTSHVSVLGEDGSAVAATSTINTP 378


>gi|153266901 gamma-glutamyltransferase 5 isoform a [Homo sapiens]
          Length = 587

 Score = 30.0 bits (66), Expect = 7.8
 Identities = 11/39 (28%), Positives = 24/39 (61%)

Query: 109 ELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPP 147
           +L+HY +  ++ + T  +++S++ EDG+ +  TS    P
Sbjct: 372 QLSHYSLAEAWGHGTGTSHVSVLGEDGSAVAATSTINTP 410


>gi|153266885 gamma-glutamyltransferase 5 isoform b [Homo sapiens]
          Length = 586

 Score = 30.0 bits (66), Expect = 7.8
 Identities = 11/39 (28%), Positives = 24/39 (61%)

Query: 109 ELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPP 147
           +L+HY +  ++ + T  +++S++ EDG+ +  TS    P
Sbjct: 372 QLSHYSLAEAWGHGTGTSHVSVLGEDGSAVAATSTINTP 410


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.136    0.415 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,339,650
Number of Sequences: 37866
Number of extensions: 1449276
Number of successful extensions: 3167
Number of sequences better than 10.0: 29
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 3098
Number of HSP's gapped (non-prelim): 42
length of query: 719
length of database: 18,247,518
effective HSP length: 110
effective length of query: 609
effective length of database: 14,082,258
effective search space: 8576095122
effective search space used: 8576095122
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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