BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|62460633 RNA-binding motif protein 16 [Homo sapiens] (1271 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|62460633 RNA-binding motif protein 16 [Homo sapiens] 2580 0.0 gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1 [... 682 0.0 gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 ... 671 0.0 gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2 ... 648 0.0 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 88 6e-17 gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 80 1e-14 gi|47132519 Ras association and pleckstrin homology domains 1 is... 77 8e-14 gi|160707881 formin 2 [Homo sapiens] 72 3e-12 gi|16554449 zonadhesin isoform 3 [Homo sapiens] 72 4e-12 gi|27881494 zonadhesin isoform 6 [Homo sapiens] 72 4e-12 gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 70 2e-11 gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 70 2e-11 gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo s... 70 2e-11 gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 70 2e-11 gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 69 2e-11 gi|14670268 RD RNA-binding protein [Homo sapiens] 69 3e-11 gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens] 69 4e-11 gi|24307919 small nuclear ribonucleoprotein 27kDa (U4/U6.U5) [Ho... 67 8e-11 gi|146134388 YLP motif containing 1 [Homo sapiens] 67 8e-11 gi|4508017 zinc finger protein 207 isoform a [Homo sapiens] 67 1e-10 gi|9558733 transformer-2 alpha [Homo sapiens] 67 1e-10 gi|4759098 splicing factor, arginine/serine-rich 10 [Homo sapiens] 67 1e-10 gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 66 2e-10 gi|33620745 pre-mRNA cleavage complex II protein Pcf11 [Homo sap... 66 2e-10 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 65 4e-10 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 65 4e-10 gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 65 5e-10 gi|163965366 nascent polypeptide-associated complex alpha subuni... 64 7e-10 gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sap... 64 7e-10 gi|38683816 ankyrin repeat domain protein 17 isoform b [Homo sap... 64 7e-10 >gi|62460633 RNA-binding motif protein 16 [Homo sapiens] Length = 1271 Score = 2580 bits (6688), Expect = 0.0 Identities = 1271/1271 (100%), Positives = 1271/1271 (100%) Query: 1 MEAVKTFNSELYSLNDYKPPISKAKMTQITKAAIKAIKFYKHVVQSVEKFIQKCKPEYKV 60 MEAVKTFNSELYSLNDYKPPISKAKMTQITKAAIKAIKFYKHVVQSVEKFIQKCKPEYKV Sbjct: 1 MEAVKTFNSELYSLNDYKPPISKAKMTQITKAAIKAIKFYKHVVQSVEKFIQKCKPEYKV 60 Query: 61 PGLYVIDSIVRQSRHQFGQEKDVFAPRFSNNIISTFQNLYRCPGDDKSKIVRVLNLWQKN 120 PGLYVIDSIVRQSRHQFGQEKDVFAPRFSNNIISTFQNLYRCPGDDKSKIVRVLNLWQKN Sbjct: 61 PGLYVIDSIVRQSRHQFGQEKDVFAPRFSNNIISTFQNLYRCPGDDKSKIVRVLNLWQKN 120 Query: 121 NVFKSEIIQPLLDMAAGIPPPVVTPVLASTTTAMSNTPGTPVTPVTPANVVQGLPDPWVS 180 NVFKSEIIQPLLDMAAGIPPPVVTPVLASTTTAMSNTPGTPVTPVTPANVVQGLPDPWVS Sbjct: 121 NVFKSEIIQPLLDMAAGIPPPVVTPVLASTTTAMSNTPGTPVTPVTPANVVQGLPDPWVS 180 Query: 181 QITNTDTLAAVAQILQSPQGQQLQQLIQTLQIQQQKPQPSILQALDAGLVVQLQALTAQL 240 QITNTDTLAAVAQILQSPQGQQLQQLIQTLQIQQQKPQPSILQALDAGLVVQLQALTAQL Sbjct: 181 QITNTDTLAAVAQILQSPQGQQLQQLIQTLQIQQQKPQPSILQALDAGLVVQLQALTAQL 240 Query: 241 TAAAAAANTLTPLEQGVSFNKKLMDRFDFGEDSEHSEEPKKEIPASQLSHVSESVNNSIF 300 TAAAAAANTLTPLEQGVSFNKKLMDRFDFGEDSEHSEEPKKEIPASQLSHVSESVNNSIF Sbjct: 241 TAAAAAANTLTPLEQGVSFNKKLMDRFDFGEDSEHSEEPKKEIPASQLSHVSESVNNSIF 300 Query: 301 HQIAEQLQQQNLEHLRQQLLEQQQPQKATPQDSQEGTFGSEHSASPSQGSSQQHFLEPEV 360 HQIAEQLQQQNLEHLRQQLLEQQQPQKATPQDSQEGTFGSEHSASPSQGSSQQHFLEPEV Sbjct: 301 HQIAEQLQQQNLEHLRQQLLEQQQPQKATPQDSQEGTFGSEHSASPSQGSSQQHFLEPEV 360 Query: 361 NLDDSIDIQQQDMDIDEGQDGVEEEVFEQEAKKVAVRSRSRTHSRSRSRSPRKRRSRSRS 420 NLDDSIDIQQQDMDIDEGQDGVEEEVFEQEAKKVAVRSRSRTHSRSRSRSPRKRRSRSRS Sbjct: 361 NLDDSIDIQQQDMDIDEGQDGVEEEVFEQEAKKVAVRSRSRTHSRSRSRSPRKRRSRSRS 420 Query: 421 GSRKRKHRKRSRSRSRERKRKSSRSYSSERRAREREKERQKKGLPPIRSKTLSVCSTTLW 480 GSRKRKHRKRSRSRSRERKRKSSRSYSSERRAREREKERQKKGLPPIRSKTLSVCSTTLW Sbjct: 421 GSRKRKHRKRSRSRSRERKRKSSRSYSSERRAREREKERQKKGLPPIRSKTLSVCSTTLW 480 Query: 481 VGQVDKKATQQDLTNLFEEFGQIESINMIPPRGCAYVCMVHRQDAFRALQKLSSGSYKIG 540 VGQVDKKATQQDLTNLFEEFGQIESINMIPPRGCAYVCMVHRQDAFRALQKLSSGSYKIG Sbjct: 481 VGQVDKKATQQDLTNLFEEFGQIESINMIPPRGCAYVCMVHRQDAFRALQKLSSGSYKIG 540 Query: 541 SKVIKIAWALNKGVKTEYKQFWDVDLGVTYIPWEKVKVDDLEGFAEGGMIDQETVNTEWE 600 SKVIKIAWALNKGVKTEYKQFWDVDLGVTYIPWEKVKVDDLEGFAEGGMIDQETVNTEWE Sbjct: 541 SKVIKIAWALNKGVKTEYKQFWDVDLGVTYIPWEKVKVDDLEGFAEGGMIDQETVNTEWE 600 Query: 601 TVKSSEPVKETVQTTQSPTPVEKETVVTTQAEVFPPPVAMLQIPVAPAVPTVSLVPPAFP 660 TVKSSEPVKETVQTTQSPTPVEKETVVTTQAEVFPPPVAMLQIPVAPAVPTVSLVPPAFP Sbjct: 601 TVKSSEPVKETVQTTQSPTPVEKETVVTTQAEVFPPPVAMLQIPVAPAVPTVSLVPPAFP 660 Query: 661 VSMPVPPPGFSPIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPPPTIPPVVPTSLVQPSL 720 VSMPVPPPGFSPIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPPPTIPPVVPTSLVQPSL Sbjct: 661 VSMPVPPPGFSPIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPPPTIPPVVPTSLVQPSL 720 Query: 721 SMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDHQISS 780 SMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDHQISS Sbjct: 721 SMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDHQISS 780 Query: 781 GENTRSVIPNDISSNAAILGGQPPNVTSNSGILGVQRPNVSSNSEILGVRPSNVSSSSGI 840 GENTRSVIPNDISSNAAILGGQPPNVTSNSGILGVQRPNVSSNSEILGVRPSNVSSSSGI Sbjct: 781 GENTRSVIPNDISSNAAILGGQPPNVTSNSGILGVQRPNVSSNSEILGVRPSNVSSSSGI 840 Query: 841 IAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGLLGTQ 900 IAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGLLGTQ Sbjct: 841 IAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGLLGTQ 900 Query: 901 PPAGPQNLPPLSIPNQRMPTMPMLDIRPGLIPQAPGPRFPLIQPGIPPQRGIPPPSVLDS 960 PPAGPQNLPPLSIPNQRMPTMPMLDIRPGLIPQAPGPRFPLIQPGIPPQRGIPPPSVLDS Sbjct: 901 PPAGPQNLPPLSIPNQRMPTMPMLDIRPGLIPQAPGPRFPLIQPGIPPQRGIPPPSVLDS 960 Query: 961 ALHPPPRGPFPPGDIFSQPERPFLAPGRQSVDNVTNPEKRIPLGNDNIQQEGDRDYRFPP 1020 ALHPPPRGPFPPGDIFSQPERPFLAPGRQSVDNVTNPEKRIPLGNDNIQQEGDRDYRFPP Sbjct: 961 ALHPPPRGPFPPGDIFSQPERPFLAPGRQSVDNVTNPEKRIPLGNDNIQQEGDRDYRFPP 1020 Query: 1021 IETRESISRPPPVDVRDVVGRPIDPREGPGRPPLDGRDHFGRPPVDIRENLVRPGIDHLG 1080 IETRESISRPPPVDVRDVVGRPIDPREGPGRPPLDGRDHFGRPPVDIRENLVRPGIDHLG Sbjct: 1021 IETRESISRPPPVDVRDVVGRPIDPREGPGRPPLDGRDHFGRPPVDIRENLVRPGIDHLG 1080 Query: 1081 RRDHFGFNPEKPWGHRGDFDEREHRVLPVYGGPKGLHEERGRFRSGNYRFDPRSGPWNRG 1140 RRDHFGFNPEKPWGHRGDFDEREHRVLPVYGGPKGLHEERGRFRSGNYRFDPRSGPWNRG Sbjct: 1081 RRDHFGFNPEKPWGHRGDFDEREHRVLPVYGGPKGLHEERGRFRSGNYRFDPRSGPWNRG 1140 Query: 1141 FGQEVHRDFDDRRRPWERQRDRDDRDFDFCREMNGNRLGRDRIQNTWVPPPHARVFDYFE 1200 FGQEVHRDFDDRRRPWERQRDRDDRDFDFCREMNGNRLGRDRIQNTWVPPPHARVFDYFE Sbjct: 1141 FGQEVHRDFDDRRRPWERQRDRDDRDFDFCREMNGNRLGRDRIQNTWVPPPHARVFDYFE 1200 Query: 1201 GATSQRKGDNVPQVNGENTERHAQPPPIPVQNDPELYEKLTSSNEINKEKSDTVADIESE 1260 GATSQRKGDNVPQVNGENTERHAQPPPIPVQNDPELYEKLTSSNEINKEKSDTVADIESE Sbjct: 1201 GATSQRKGDNVPQVNGENTERHAQPPPIPVQNDPELYEKLTSSNEINKEKSDTVADIESE 1260 Query: 1261 PVVESTETEGT 1271 PVVESTETEGT Sbjct: 1261 PVVESTETEGT 1271 >gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1 [Homo sapiens] Length = 1147 Score = 682 bits (1759), Expect = 0.0 Identities = 495/1278 (38%), Positives = 653/1278 (51%), Gaps = 261/1278 (20%) Query: 1 MEAVKTFNSELYSLNDYKPPISKAKMTQITKAAIKAIKFYKHVVQSVEKFIQKCKPEYKV 60 M+AV FN EL+SL D KPPIS+AKM ITKAAIKAIK YKHVVQ VEKFI+KCKPEYKV Sbjct: 1 MDAVNAFNQELFSLMDMKPPISRAKMILITKAAIKAIKLYKHVVQIVEKFIKKCKPEYKV 60 Query: 61 PGLYVIDSIVRQSRHQFGQEKDVFAPRFSNNIISTFQNLYRCPGDDKSKIVRVLNLWQKN 120 PGLYVIDSIVRQSRHQFG +KDVF PRFS NI +TFQ LY CP +DKSKIVRVLNLWQKN Sbjct: 61 PGLYVIDSIVRQSRHQFGTDKDVFGPRFSKNITATFQYLYLCPSEDKSKIVRVLNLWQKN 120 Query: 121 NVFKSEIIQPLLDMAAGIPPPVVTPVLASTTTAMSNTPGTPVTPVTPANV--VQGLPD-- 176 VFK EIIQPLLDMAAG T A ++N G+P PV ++ Q P+ Sbjct: 121 GVFKIEIIQPLLDMAAG------TSNAAPVAENVTNNEGSPPPPVKVSSEPPTQATPNSV 174 Query: 177 PWVSQITNTDTLAAVAQILQSPQGQQLQQLIQTLQIQQQKPQPSILQALDAGLVVQLQAL 236 P V Q+ ++D AAVAQ+ Q+ QGQQLQQ++QT Q Q KPQ ALD ++ Q+QA+ Sbjct: 175 PAVPQLPSSDAFAAVAQLFQTTQGQQLQQILQTFQ-QPPKPQSP---ALDNAVMAQVQAI 230 Query: 237 TAQL----TAAAAAANTLTPLEQGVSFNKKLMDRFDFGEDSEHSEEPKKE---------- 282 TAQL T + P EQ +F+KKL+DRFD+ ++ E EE KKE Sbjct: 231 TAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAP 290 Query: 283 -----------IPASQL-SHVSESVNNSIFHQIAEQLQQ------QNLEHLRQQLLEQQQ 324 +PA+ + S + F + +QQ QN++ + +++ QQ Sbjct: 291 AAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQ 350 Query: 325 P----QKATPQDSQEGTFGSEHSASPSQGSSQQHFLEPE--VNLDDSIDIQQQDMDIDEG 378 Q P + Q FG +P Q + P V Q Q+ + + Sbjct: 351 DPMHHQVPLPPNGQMPGFGL--LPTPPFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQK 408 Query: 379 QDGVEEEVFE---QEAKKVAVRSRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRKRSRSRS 435 E EV + QE K+ +R ++ SRS SRSP++RRSRS S SR+ +HR RSRSRS Sbjct: 409 PHQQEMEVEQPCIQEVKRHMSDNR-KSRSRSASRSPKRRRSRSGSRSRRSRHR-RSRSRS 466 Query: 436 RERKRKSSRSYSSERRAREREKERQKKGLPPIRSKTLSVCSTTLWVGQVDKKATQQDLTN 495 R+R+R S RS S ERR RE+E+ER++KGLP ++ +T SVCSTTLWVGQ+DK+ TQQD+ + Sbjct: 467 RDRRRHSPRSRSQERRDREKERERRQKGLPQVKPETASVCSTTLWVGQLDKRTTQQDVAS 526 Query: 496 LFEEFGQIESINMIPPRGCAYVCMVHRQDAFRALQKLSSGSYKIGSKVIKIAWALNKGVK 555 L EEFG IESINMIPPRGCAY+ MVHRQDA+RALQKLS G+YK+ K IKIAWALNKG+K Sbjct: 527 LLEEFGPIESINMIPPRGCAYIVMVHRQDAYRALQKLSRGNYKVNQKSIKIAWALNKGIK 586 Query: 556 TEYKQFWDVDLGVTYIPWEKVKVDDLEGFAEGGMIDQETVNTEWETVKSSEPVKETVQT- 614 +YKQ+WDV+LGVTYIPW+KVK ++LE F EGGM+D +T+N +W+ + +P E Q Sbjct: 587 ADYKQYWDVELGVTYIPWDKVKPEELESFCEGGMLDSDTLNPDWKGI-PKKPENEVAQNG 645 Query: 615 ------TQSPTPVEKETVVTTQAEVFPPPVAM--LQIPV-APAVPTV-SLVPPAFPVSMP 664 T+ +P+ K V P P+ + Q+P P P V +L PPAF + Sbjct: 646 GAETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLG 705 Query: 665 VPPPGFS-----PIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPPPTIPP--VVPTSLVQ 717 +PPPGF P PPPPFLR FNP PPGF+PP PPP+ PP +IPP P S+ Sbjct: 706 IPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPN 765 Query: 718 PSLS-MTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDH 776 +++ + +T KD+ G+ P V + AE + V Sbjct: 766 STIAGINEDTTKDLSIGN-----------------PIPTVVSGARGNAESGDSV------ 802 Query: 777 QISSGENTRSVIPNDISSNAAILGGQPPNVTSNSGILGVQRPNVSSNSEILGVRPSNVSS 836 + S +P +N P VT +LG Q GV P V Sbjct: 803 -----KMYGSAVPPAAPTNL-----PTPPVTQPVSLLGTQ-----------GVAPGPV-- 839 Query: 837 SSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGL 896 +G+Q P S+GLLG PGL Sbjct: 840 ------------------IGLQAP----STGLLGA---------------------RPGL 856 Query: 897 LGTQPPAGPQNLPPLSIPNQRMPTMPMLDIRPGLIPQAPGPRFPLIQPGIPPQRGIPPPS 956 + Q P G +PP + QR P MP + P ++ + P P P +PPP Sbjct: 857 IPLQRPPG---MPPPHL--QRFPLMPPRPMPPHMMHRGPPPG--------PGGFAMPPPH 903 Query: 957 VLDSALHPPPRGPFPPGDIFSQPERPFLAPGRQSVDNVTNPEKRIPLGNDNIQQEGDRDY 1016 + +GPFP P PF+ PG P P D QQ + Sbjct: 904 GM--------KGPFP-------PHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQ 948 Query: 1017 RFPPIET-----RESISRPPPVDVRDVVGRPIDPREGPGRPPLDGRDHF--GRPPVDIRE 1069 + P + ++ +PPP +P ++ P + D R F GR Sbjct: 949 QQPQPQAPQQPQQQQQQQPPPSQ------QPPPTQQQPQQFRNDNRQQFNSGRDQ----- 997 Query: 1070 NLVRPGIDHLGRRDHFG---FNPEKPWGHRGDFDEREHRVLPVYGGPKGLHEERGRFRSG 1126 + GRR FG N + +G+R D + +R +G Sbjct: 998 -------ERFGRRS-FGNRVENDRERYGNRNDDRDNSNRDRREWG--------------- 1034 Query: 1127 NYRFDPRSGPWNRGFGQEVHRDFDDRRR--PWERQRDRDDRDFDFCREMNGNRLGRDRIQ 1184 R ++ HRD ++R R R R+RD RD + RE R G+++ + Sbjct: 1035 -----------RRSPDRDRHRDLEERNRRSSGHRDRERDSRDRESRREKEEAR-GKEKPE 1082 Query: 1185 -------NTWVPPPHARV 1195 N V PP ++V Sbjct: 1083 VTDRAGGNKTVEPPISQV 1100 Score = 39.7 bits (91), Expect = 0.019 Identities = 47/201 (23%), Positives = 77/201 (38%), Gaps = 20/201 (9%) Query: 322 QQQPQKATPQDSQEGTFGSEHSASPSQGS--SQQHFLEPEVNLDDSIDIQQQDMDIDEGQ 379 QQQPQ PQ Q+ + PSQ +QQ +P+ +D+ +Q + Q Sbjct: 948 QQQPQPQAPQQPQQQ---QQQQPPPSQQPPPTQQ---QPQQFRNDN----RQQFNSGRDQ 997 Query: 380 DGVEEEVFEQEAKKVAVRSRSRTHSRSRSRSPRK---RRSRSRSGSRKRKHRKRSRSRSR 436 + F + R +R R S R+ RRS R R + R R S R Sbjct: 998 ERFGRRSFGNRVENDRERYGNRNDDRDNSNRDRREWGRRSPDRDRHRDLEERNRRSSGHR 1057 Query: 437 ERKRKSSRSYSSERRAREREKERQKKGLPPIRSKTLSVCSTTLWVGQVDKKATQQDLTNL 496 +R+R S +R +R ++E + K P + + + + QV T +L Sbjct: 1058 DRERD-----SRDRESRREKEEARGKEKPEVTDRAGGNKTVEPPISQVGNVDTASELEKG 1112 Query: 497 FEEFGQIESINMIPPRGCAYV 517 E ++ +P + V Sbjct: 1113 VSEAAVLKPSEELPAEATSSV 1133 >gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 [Homo sapiens] Length = 1125 Score = 671 bits (1731), Expect = 0.0 Identities = 459/1098 (41%), Positives = 591/1098 (53%), Gaps = 189/1098 (17%) Query: 1 MEAVKTFNSELYSLNDYKPPISKAKMTQITKAAIKAIKFYKHVVQSVEKFIQKCKPEYKV 60 M+AV FN EL+SL D KPPIS+AKM ITKAAIKAIK YKHVVQ VEKFI+KCKPEYKV Sbjct: 1 MDAVNAFNQELFSLMDMKPPISRAKMILITKAAIKAIKLYKHVVQIVEKFIKKCKPEYKV 60 Query: 61 PGLYVIDSIVRQSRHQFGQEKDVFAPRFSNNIISTFQNLYRCPGDDKSKIVRVLNLWQKN 120 PGLYVIDSIVRQSRHQFG +KDVF PRFS NI +TFQ LY CP +DKSKIVRVLNLWQKN Sbjct: 61 PGLYVIDSIVRQSRHQFGTDKDVFGPRFSKNITATFQYLYLCPSEDKSKIVRVLNLWQKN 120 Query: 121 NVFKSEIIQPLLDMAAGIPPPVVTPVLASTTTAMSNTPGTPVTPVTPANV--VQGLPD-- 176 VFK EIIQPLLDMAAG T A ++N G+P PV ++ Q P+ Sbjct: 121 GVFKIEIIQPLLDMAAG------TSNAAPVAENVTNNEGSPPPPVKVSSEPPTQATPNSV 174 Query: 177 PWVSQITNTDTLAAVAQILQSPQGQQLQQLIQTLQIQQQKPQPSILQALDAGLVVQLQAL 236 P V Q+ ++D AAVAQ+ Q+ QGQQLQQ++QT Q Q KPQ ALD ++ Q+QA+ Sbjct: 175 PAVPQLPSSDAFAAVAQLFQTTQGQQLQQILQTFQ-QPPKPQSP---ALDNAVMAQVQAI 230 Query: 237 TAQL----TAAAAAANTLTPLEQGVSFNKKLMDRFDFGEDSEHSEEPKKE---------- 282 TAQL T + P EQ +F+KKL+DRFD+ ++ E EE KKE Sbjct: 231 TAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAP 290 Query: 283 -----------IPASQL-SHVSESVNNSIFHQIAEQLQQ------QNLEHLRQQLLEQQQ 324 +PA+ + S + F + +QQ QN++ + +++ QQ Sbjct: 291 AAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQ 350 Query: 325 P----QKATPQDSQEGTFGSEHSASPSQGSSQQHFLEPE--VNLDDSIDIQQQDMDIDEG 378 Q P + Q FG +P Q + P V Q Q+ + + Sbjct: 351 DPMHHQVPLPPNGQMPGFGL--LPTPPFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQK 408 Query: 379 QDGVEEEVFE---QEAKKVAVRSRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRKRSRSRS 435 E EV + QE K+ +R ++ SRS SRSP++RRSRS S SR+ +HR RSRSRS Sbjct: 409 PHQQEMEVEQPCIQEVKRHMSDNR-KSRSRSASRSPKRRRSRSGSRSRRSRHR-RSRSRS 466 Query: 436 RERKRKSSRSYSSERRAREREKERQKKGLPPIRSKTLSVCSTTLWVGQVDKKATQQDLTN 495 R+R+R S RS S ERR RE+E+ER++KGLP ++ +T SVCSTTLWVGQ+DK+ TQQD+ + Sbjct: 467 RDRRRHSPRSRSQERRDREKERERRQKGLPQVKPETASVCSTTLWVGQLDKRTTQQDVAS 526 Query: 496 LFEEFGQIESINMIPPRGCAYVCMVHRQDAFRALQKLSSGSYKIGSKVIKIAWALNKGVK 555 L EEFG IESINMIPPRGCAY+ MVHRQDA+RALQKLS G+YK+ K IKIAWALNKG+K Sbjct: 527 LLEEFGPIESINMIPPRGCAYIVMVHRQDAYRALQKLSRGNYKVNQKSIKIAWALNKGIK 586 Query: 556 TEYKQFWDVDLGVTYIPWEKVKVDDLEGFAEGGMIDQETVNTEWETVKSSEPVKETVQT- 614 +YKQ+WDV+LGVTYIPW+KVK ++LE F EGGM+D +T+N +W+ + +P E Q Sbjct: 587 ADYKQYWDVELGVTYIPWDKVKPEELESFCEGGMLDSDTLNPDWKGI-PKKPENEVAQNG 645 Query: 615 ------TQSPTPVEKETVVTTQAEVFPPPVAM--LQIPV-APAVPTV-SLVPPAFPVSMP 664 T+ +P+ K V P P+ + Q+P P P V +L PPAF + Sbjct: 646 GAETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLG 705 Query: 665 VPPPGFS-----PIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPPPTIPPVVPTSLVQPS 719 +PPPGF P PPPPFLR FNP PPGF+PP PPP+ PP +IPP + P+ Sbjct: 706 IPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPN 765 Query: 720 LSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDHQIS 779 L G G SV + SA+P N PT Sbjct: 766 LVS--------GARGNAESGDSV--KMYGSAVPPAAPTNLPT------------------ 797 Query: 780 SGENTRSVIPNDISSNAAILGGQPPNVTSNSGILGVQRPNVSSNSEILGVRPSNV----S 835 P VT +LG Q GV P V + Sbjct: 798 ------------------------PPVTQPVSLLGTQ-----------GVAPGPVIGLQA 822 Query: 836 SSSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPG 895 S+G++ A+P G++ +Q P G+ PP++ + PP P P Sbjct: 823 PSTGLLGARP-------GLIPLQRPP--------GMPPPHLQR----FPLMPPR-PMPPH 862 Query: 896 LLGTQPPAGPQNL---PPLSIPNQRMPTMPMLDIRPGLIPQAPGP-------------RF 939 ++ PP GP PP + P P +RPG +P GP + Sbjct: 863 MMHRGPPPGPGGFAMPPPHGMKGPFPPHGPF--VRPGGMPGLGGPGPGPGGPEDRDGRQQ 920 Query: 940 PLIQPGIPPQRGIPPPSVLDSALHPPPRGPFPPGDIFSQPERPFLAPGRQSVDNVTNPEK 999 P QP PQ P PPP PP QP++ F RQ ++ + E+ Sbjct: 921 PPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQ--QQPQQ-FRNDNRQQFNSGRDQER 977 Query: 1000 --RIPLGNDNIQQEGDRD 1015 R GN + E DR+ Sbjct: 978 FGRRSFGN---RVENDRE 992 Score = 39.7 bits (91), Expect = 0.019 Identities = 47/201 (23%), Positives = 77/201 (38%), Gaps = 20/201 (9%) Query: 322 QQQPQKATPQDSQEGTFGSEHSASPSQGS--SQQHFLEPEVNLDDSIDIQQQDMDIDEGQ 379 QQQPQ PQ Q+ + PSQ +QQ +P+ +D+ +Q + Q Sbjct: 926 QQQPQPQAPQQPQQQ---QQQQPPPSQQPPPTQQ---QPQQFRNDN----RQQFNSGRDQ 975 Query: 380 DGVEEEVFEQEAKKVAVRSRSRTHSRSRSRSPRK---RRSRSRSGSRKRKHRKRSRSRSR 436 + F + R +R R S R+ RRS R R + R R S R Sbjct: 976 ERFGRRSFGNRVENDRERYGNRNDDRDNSNRDRREWGRRSPDRDRHRDLEERNRRSSGHR 1035 Query: 437 ERKRKSSRSYSSERRAREREKERQKKGLPPIRSKTLSVCSTTLWVGQVDKKATQQDLTNL 496 +R+R S +R +R ++E + K P + + + + QV T +L Sbjct: 1036 DRERD-----SRDRESRREKEEARGKEKPEVTDRAGGNKTVEPPISQVGNVDTASELEKG 1090 Query: 497 FEEFGQIESINMIPPRGCAYV 517 E ++ +P + V Sbjct: 1091 VSEAAVLKPSEELPAEATSSV 1111 >gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2 [Homo sapiens] Length = 1132 Score = 648 bits (1672), Expect = 0.0 Identities = 483/1278 (37%), Positives = 640/1278 (50%), Gaps = 276/1278 (21%) Query: 1 MEAVKTFNSELYSLNDYKPPISKAKMTQITKAAIKAIKFYKHVVQSVEKFIQKCKPEYKV 60 M+AV FN EL+SL D KPPIS+AKM ITKAAIKAIK CKPEYKV Sbjct: 1 MDAVNAFNQELFSLMDMKPPISRAKMILITKAAIKAIK---------------CKPEYKV 45 Query: 61 PGLYVIDSIVRQSRHQFGQEKDVFAPRFSNNIISTFQNLYRCPGDDKSKIVRVLNLWQKN 120 PGLYVIDSIVRQSRHQFG +KDVF PRFS NI +TFQ LY CP +DKSKIVRVLNLWQKN Sbjct: 46 PGLYVIDSIVRQSRHQFGTDKDVFGPRFSKNITATFQYLYLCPSEDKSKIVRVLNLWQKN 105 Query: 121 NVFKSEIIQPLLDMAAGIPPPVVTPVLASTTTAMSNTPGTPVTPVTPANV--VQGLPD-- 176 VFK EIIQPLLDMAAG T A ++N G+P PV ++ Q P+ Sbjct: 106 GVFKIEIIQPLLDMAAG------TSNAAPVAENVTNNEGSPPPPVKVSSEPPTQATPNSV 159 Query: 177 PWVSQITNTDTLAAVAQILQSPQGQQLQQLIQTLQIQQQKPQPSILQALDAGLVVQLQAL 236 P V Q+ ++D AAVAQ+ Q+ QGQQLQQ++QT Q Q KPQ ALD ++ Q+QA+ Sbjct: 160 PAVPQLPSSDAFAAVAQLFQTTQGQQLQQILQTFQ-QPPKPQSP---ALDNAVMAQVQAI 215 Query: 237 TAQL----TAAAAAANTLTPLEQGVSFNKKLMDRFDFGEDSEHSEEPKKE---------- 282 TAQL T + P EQ +F+KKL+DRFD+ ++ E EE KKE Sbjct: 216 TAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAP 275 Query: 283 -----------IPASQL-SHVSESVNNSIFHQIAEQLQQ------QNLEHLRQQLLEQQQ 324 +PA+ + S + F + +QQ QN++ + +++ QQ Sbjct: 276 AAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQ 335 Query: 325 P----QKATPQDSQEGTFGSEHSASPSQGSSQQHFLEPE--VNLDDSIDIQQQDMDIDEG 378 Q P + Q FG +P Q + P V Q Q+ + + Sbjct: 336 DPMHHQVPLPPNGQMPGFGL--LPTPPFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQK 393 Query: 379 QDGVEEEVFE---QEAKKVAVRSRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRKRSRSRS 435 E EV + QE K+ +R ++ SRS SRSP++RRSRS S SR+ +HR RSRSRS Sbjct: 394 PHQQEMEVEQPCIQEVKRHMSDNR-KSRSRSASRSPKRRRSRSGSRSRRSRHR-RSRSRS 451 Query: 436 RERKRKSSRSYSSERRAREREKERQKKGLPPIRSKTLSVCSTTLWVGQVDKKATQQDLTN 495 R+R+R S RS S ERR RE+E+ER++KGLP ++ +T SVCSTTLWVGQ+DK+ TQQD+ + Sbjct: 452 RDRRRHSPRSRSQERRDREKERERRQKGLPQVKPETASVCSTTLWVGQLDKRTTQQDVAS 511 Query: 496 LFEEFGQIESINMIPPRGCAYVCMVHRQDAFRALQKLSSGSYKIGSKVIKIAWALNKGVK 555 L EEFG IESINMIPPRGCAY+ MVHRQDA+RALQKLS G+YK+ K IKIAWALNKG+K Sbjct: 512 LLEEFGPIESINMIPPRGCAYIVMVHRQDAYRALQKLSRGNYKVNQKSIKIAWALNKGIK 571 Query: 556 TEYKQFWDVDLGVTYIPWEKVKVDDLEGFAEGGMIDQETVNTEWETVKSSEPVKETVQT- 614 +YKQ+WDV+LGVTYIPW+KVK ++LE F EGGM+D +T+N +W+ + +P E Q Sbjct: 572 ADYKQYWDVELGVTYIPWDKVKPEELESFCEGGMLDSDTLNPDWKGI-PKKPENEVAQNG 630 Query: 615 ------TQSPTPVEKETVVTTQAEVFPPPVAM--LQIPV-APAVPTV-SLVPPAFPVSMP 664 T+ +P+ K V P P+ + Q+P P P V +L PPAF + Sbjct: 631 GAETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLG 690 Query: 665 VPPPGFS-----PIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPPPTIPP--VVPTSLVQ 717 +PPPGF P PPPPFLR FNP PPGF+PP PPP+ PP +IPP P S+ Sbjct: 691 IPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPN 750 Query: 718 PSLS-MTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDH 776 +++ + +T KD+ G+ P V + AE + V Sbjct: 751 STIAGINEDTTKDLSIGN-----------------PIPTVVSGARGNAESGDSV------ 787 Query: 777 QISSGENTRSVIPNDISSNAAILGGQPPNVTSNSGILGVQRPNVSSNSEILGVRPSNVSS 836 + S +P +N P VT +LG Q GV P V Sbjct: 788 -----KMYGSAVPPAAPTNL-----PTPPVTQPVSLLGTQ-----------GVAPGPV-- 824 Query: 837 SSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGL 896 +G+Q P S+GLLG PGL Sbjct: 825 ------------------IGLQAP----STGLLGA---------------------RPGL 841 Query: 897 LGTQPPAGPQNLPPLSIPNQRMPTMPMLDIRPGLIPQAPGPRFPLIQPGIPPQRGIPPPS 956 + Q P G +PP + QR P MP + P ++ + P P P +PPP Sbjct: 842 IPLQRPPG---MPPPHL--QRFPLMPPRPMPPHMMHRGPPPG--------PGGFAMPPPH 888 Query: 957 VLDSALHPPPRGPFPPGDIFSQPERPFLAPGRQSVDNVTNPEKRIPLGNDNIQQEGDRDY 1016 + +GPFP P PF+ PG P P D QQ + Sbjct: 889 GM--------KGPFP-------PHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQ 933 Query: 1017 RFPPIET-----RESISRPPPVDVRDVVGRPIDPREGPGRPPLDGRDHF--GRPPVDIRE 1069 + P + ++ +PPP +P ++ P + D R F GR Sbjct: 934 QQPQPQAPQQPQQQQQQQPPPSQ------QPPPTQQQPQQFRNDNRQQFNSGRDQ----- 982 Query: 1070 NLVRPGIDHLGRRDHFG---FNPEKPWGHRGDFDEREHRVLPVYGGPKGLHEERGRFRSG 1126 + GRR FG N + +G+R D + +R +G Sbjct: 983 -------ERFGRRS-FGNRVENDRERYGNRNDDRDNSNRDRREWG--------------- 1019 Query: 1127 NYRFDPRSGPWNRGFGQEVHRDFDDRRR--PWERQRDRDDRDFDFCREMNGNRLGRDRIQ 1184 R ++ HRD ++R R R R+RD RD + RE R G+++ + Sbjct: 1020 -----------RRSPDRDRHRDLEERNRRSSGHRDRERDSRDRESRREKEEAR-GKEKPE 1067 Query: 1185 -------NTWVPPPHARV 1195 N V PP ++V Sbjct: 1068 VTDRAGGNKTVEPPISQV 1085 Score = 39.7 bits (91), Expect = 0.019 Identities = 47/201 (23%), Positives = 77/201 (38%), Gaps = 20/201 (9%) Query: 322 QQQPQKATPQDSQEGTFGSEHSASPSQGS--SQQHFLEPEVNLDDSIDIQQQDMDIDEGQ 379 QQQPQ PQ Q+ + PSQ +QQ +P+ +D+ +Q + Q Sbjct: 933 QQQPQPQAPQQPQQQ---QQQQPPPSQQPPPTQQ---QPQQFRNDN----RQQFNSGRDQ 982 Query: 380 DGVEEEVFEQEAKKVAVRSRSRTHSRSRSRSPRK---RRSRSRSGSRKRKHRKRSRSRSR 436 + F + R +R R S R+ RRS R R + R R S R Sbjct: 983 ERFGRRSFGNRVENDRERYGNRNDDRDNSNRDRREWGRRSPDRDRHRDLEERNRRSSGHR 1042 Query: 437 ERKRKSSRSYSSERRAREREKERQKKGLPPIRSKTLSVCSTTLWVGQVDKKATQQDLTNL 496 +R+R S +R +R ++E + K P + + + + QV T +L Sbjct: 1043 DRERD-----SRDRESRREKEEARGKEKPEVTDRAGGNKTVEPPISQVGNVDTASELEKG 1097 Query: 497 FEEFGQIESINMIPPRGCAYV 517 E ++ +P + V Sbjct: 1098 VSEAAVLKPSEELPAEATSSV 1118 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 87.8 bits (216), Expect = 6e-17 Identities = 118/422 (27%), Positives = 160/422 (37%), Gaps = 82/422 (19%) Query: 605 SEPVKETVQTTQSP--TPVEKETV-----VTTQAEVFPPPVAMLQIPVAP----AVPTVS 653 S+P + +Q + P TP K+ +++ P P PV P A P + Sbjct: 270 SQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPA 329 Query: 654 LVPPAFPVSMPVPPPGFSPIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPPP---TIPPV 710 +PP+ P++ P+P SP PP P+ PP P PP+ PP TIPP+ Sbjct: 330 TLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPI 389 Query: 711 -VPTSLVQPSLSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEPE-- 767 VP SL PSL P S LA S+L A +PT QA Sbjct: 390 QVPHSLTSPSLQAPP-------------------SPLALSSLQATTSLGSPTLQATHSFL 430 Query: 768 EKVPHLIDHQISSGENTRSVIPNDISSNAAI-LGGQPPNVTSNSGILGVQRPNVSSNSEI 826 P ++S S P+ A + L PP TS S P VS S Sbjct: 431 TMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLS-------PAVSPLSSP 483 Query: 827 LGVRPSNVSSSSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQ 886 L + P SS +A+ P +S I+ PP + SS + Sbjct: 484 LTIHPLQALSS---LASHSPQAPLSSLIM---PPLETQSS------------------LA 519 Query: 887 PPNVPNTPGLLGTQPPAGPQNLPPLSIPNQRMPTMPMLDIRPGL-IPQAPGPRFPLIQPG 945 PP++ P L T P +NLP L+ P + + P+ P L P P P PL P Sbjct: 520 PPSLQTPPASLTTPP---LENLPSLAPPPLQTASAPL--TTPHLETPPCPAP-CPLQAP- 572 Query: 946 IPPQRGIPPPSVLDSALHPPPRGP----FPP-GDIFSQPERPFLAPGRQSVDNVTNPEKR 1000 P PPP S PPP+ P PP + S P P P Q+ + P + Sbjct: 573 -PSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQ 631 Query: 1001 IP 1002 P Sbjct: 632 AP 633 Score = 62.4 bits (150), Expect = 3e-09 Identities = 116/477 (24%), Positives = 160/477 (33%), Gaps = 91/477 (19%) Query: 617 SPTPVEKETVVTTQAEVFPPPVAM---LQIPVAPAVPTVSLVPPAFPVSMPVPPPGFSPI 673 +P P++ + T + PP LQ P +P ++ PP P S+ PPP P Sbjct: 542 APPPLQTASAPLTTPHLETPPCPAPCPLQAPPSP----LTTPPPETPSSIATPPPQAPPA 597 Query: 674 PPPPFLRASFNPSQPPPGFMPPPVPPPV-VPPPTIPPVVPTS-LVQPSLSMTPETVKDVG 731 P L+ +P P PP PP + +PP PP P S + P + +P+ + Sbjct: 598 LASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALA 657 Query: 732 FGSLVI-----PGGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDHQISSGENTRS 786 L P V + + A P + P QA P P L Sbjct: 658 VHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPL------------Q 705 Query: 787 VIPNDISSNAAILGGQPPNVTSNSGILGVQRPNVSSNSEILGVRPSNVSSSSGIIAAQPP 846 V P+ +S PP Q P + + L V PS +S +A PP Sbjct: 706 VPPSPPASPPMSPSATPP----------PQAPPPLA-APPLQVPPSPPASPPMSPSATPP 754 Query: 847 NILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGLLGTQPPAGPQ 906 + PP LL P +P + P ++P +P L PP P Sbjct: 755 PRV---------PP-------LLAAPPLQVPPS------PPASLPMSP--LAKPPPQAPP 790 Query: 907 NL--PPLSIPNQRMPTMPMLDIRPGLIPQAPGPRFPLIQPGIPPQRG----------IPP 954 L PPL Q +P+ P PG P +P P+ PP + +PP Sbjct: 791 ALATPPL----QALPSPPA--SFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPP 844 Query: 955 PSVLDSALHPPPRGPFPPGDIFSQPERPFLA--------PGRQSVDNVTNPEKRIPLGND 1006 L P R P P D R LA P R ++ P+ + Sbjct: 845 SPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSA 904 Query: 1007 NIQQEGDRDYRFPPIETRESISRPPPVDVRDVVGRPIDPREGPGRPPLDGRDHFGRP 1063 E R Y P + PP D P GP PPL R G P Sbjct: 905 TSTPEELRGYDSGP---EGGAAASPPPDAELAACHPAAWSRGPA-PPLAFRGAPGAP 957 Score = 61.6 bits (148), Expect = 5e-09 Identities = 104/413 (25%), Positives = 136/413 (32%), Gaps = 63/413 (15%) Query: 607 PVKETVQTTQSPTPVEKETVVTTQAEVFP-PPVAMLQIPVAPAVPTVSLVPP-AFPVSMP 664 P ET + +P P + + + P PP++ L P P P +PP P S P Sbjct: 579 PPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATP-PPQAPPXLALPPLQAPPSPP 637 Query: 665 VPPPGFSPIPPPP----------FLRASFNPSQPPPGFMP--PPVPPPVVPPPTIPPVVP 712 PP SP+ P L+A F+P PP P PP PPV P T P P Sbjct: 638 ASPP-LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAP 696 Query: 713 TSLVQPSLSMTPETVKDVGFGSLVIPGGSVASNLATSAL---PAGNVFNAPTKQAEPEEK 769 SL P L + P P LA L P+ + A P + Sbjct: 697 PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPR 756 Query: 770 VPHLIDHQISSGENTRSVIPNDISSNAAILGGQPPNVTSNSGILGVQRPNVSSNSEILGV 829 VP L+ V P+ +S +PP Q P + + + Sbjct: 757 VPPLL------AAPPLQVPPSPPASLPMSPLAKPP----------PQAPPALATPPLQAL 800 Query: 830 RPSNVSSSSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQPPN 889 PS +S G P L S + P + + L +PP+ P + L Q P Sbjct: 801 -PSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTL---QAPR 856 Query: 890 VPNTPG------------LLGTQPPAGPQNLP--PLSIPNQRMPTMPMLDIRPGLIPQAP 935 P TPG L PP P P LS P+ + L Sbjct: 857 RPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDS 916 Query: 936 GPRFPLIQPGIPPQRGIPPPSVLDSALHPP--PRGPFPPGDIFSQPERPFLAP 986 GP PPP +A HP RGP PP P P P Sbjct: 917 GPE--------GGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWP 961 Score = 54.7 bits (130), Expect = 6e-07 Identities = 42/124 (33%), Positives = 54/124 (43%), Gaps = 12/124 (9%) Query: 605 SEPVKETVQTTQSPTPVEKETVVTTQAEVFPPPVAMLQIPVAPAVPTVSLVPPAFPVSMP 664 S PV+ SP PV +QA PP +A + V P+ P PP P + P Sbjct: 670 SPPVQAPFSPPASP-PVSPSATPPSQA---PPSLAAPPLQVPPSPPAS---PPMSPSATP 722 Query: 665 VPPPGFSPIPPPPFLRASFNPSQPP--PGFMPPPVPPPVV--PPPTIPPVVPTSLVQPSL 720 PP P+ PP P+ PP P PPP PP++ PP +PP P SL L Sbjct: 723 -PPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPL 781 Query: 721 SMTP 724 + P Sbjct: 782 AKPP 785 Score = 53.9 bits (128), Expect = 9e-07 Identities = 91/423 (21%), Positives = 152/423 (35%), Gaps = 42/423 (9%) Query: 653 SLVPPAFPVSMPVPPPGFSPIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPP-----PTI 707 SL A P+S P + P RA +PSQP P + PP V PP P + Sbjct: 241 SLSSSATPLSSPARSGPSARGTP----RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL 296 Query: 708 PPVVPTSLVQPSLSMT------PETVKDVGFGSLVIPGGSVASNL-----ATSALPAGNV 756 P+ + L PS S T P + + P +A+ L + SA P+ Sbjct: 297 GPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQT 356 Query: 757 FNAPTKQAEPEEKVPHLIDHQISSGENTRSV----IPNDISSNAAILGGQPPNVTSNSGI 812 +P P + P + + + + +++ +P+ ++S + P ++S Sbjct: 357 LPSP-PATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQAT 415 Query: 813 LGVQRPNVSSNSEILGVRPSNVSSSSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLGVL 872 + P + + L + P +S ++P + +S L P S+ S L L Sbjct: 416 TSLGSPTLQATHSFLTMSPRQTQASL-TSPSRPASTPPDSPPLQ-APLSLPASPPLQTSL 473 Query: 873 PPNIPNNSGLVGVQPPNVPNTPGLLGTQPPAGPQNLPPLSIPNQRMPTMPMLDIRPGLIP 932 P + S + + P ++ Q P +PPL + P P L P + Sbjct: 474 SPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAP--PSLQTPPASLT 531 Query: 933 QAPGPRFPLIQPGIPPQRGIPPPSVLDSALHPPPRGPFPPGDIFSQPERPFLAPGRQSVD 992 P P + P PP + P PP P P P P P ++ Sbjct: 532 TPPLENLPSLAP--PPLQTASAPLTTPHLETPPCPAPCP----LQAPPSPLTTPPPETPS 585 Query: 993 NVTNPEKRIPLGNDNIQQEGDRDYRFPPIETRESISRPPPVDVRDVVGRPID-PREGPGR 1051 ++ P + P + +G PP+ ++ PPP + P+ P P Sbjct: 586 SIATPPPQAPPALASPPLQG---LPSPPL---SPLATPPPQAPPXLALPPLQAPPSPPAS 639 Query: 1052 PPL 1054 PPL Sbjct: 640 PPL 642 Score = 52.4 bits (124), Expect = 3e-06 Identities = 89/367 (24%), Positives = 129/367 (35%), Gaps = 73/367 (19%) Query: 636 PPVAMLQIPVAPAVPTVSLVPPAFPVSMPVPPPGFSPIPP---PPFLRASFNPSQPPPGF 692 PP++ L P A +++ P S P PP +P P PP ++ PSQ PP Sbjct: 640 PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSL 699 Query: 693 MPPPV--------PPPVVPPPTIPPVVPTSLVQPSLSMTPETVKDVGFGSLVIPGGSVAS 744 PP+ PP+ P T PP P L P L + P P V Sbjct: 700 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPP 759 Query: 745 NLATSAL-----PAGNVFNAPTKQAEPEEKVPHLIDHQISSGENTRSVIPND--ISSNAA 797 LA L P ++ +P + P+ P L + + + + P S +A+ Sbjct: 760 LLAAPPLQVPPSPPASLPMSPLAKPPPQAP-PALATPPLQALPSPPASFPGQAPFSPSAS 818 Query: 798 I----LGGQPPNVTSNSGILGVQRPNVSSNSEILGVRPSNVSSSSGIIAAQPPNILNNSG 853 + L PP Q P V + + +L V PS +S + +PP ++ Sbjct: 819 LPMSPLATPPP-----------QAPPVLA-APLLQVPPSPPASPTLQAPRRPPTPGPDTS 866 Query: 854 ILGIQ-----------PPSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGLLGTQPP 902 + G + PPS S SS L G P++ +S P + + P Sbjct: 867 VSGPRLTLALAPGPPPPPSRSPSSTLSG---PDLAGHSSSATSTPEELRG----YDSGPE 919 Query: 903 AGPQNLPPLSIPNQRMPTMPMLDIRPGLIPQAPGPRFPLIQPGIPPQRGIPPPSVLDSAL 962 G PP P + P + P P PL G P G P P Sbjct: 920 GGAAASPP--------PDAELAACHPAAWSRGPAP--PLAFRGAP---GAPLP------- 959 Query: 963 HPPPRGP 969 PP GP Sbjct: 960 WPPATGP 966 Score = 50.1 bits (118), Expect = 1e-05 Identities = 59/226 (26%), Positives = 82/226 (36%), Gaps = 24/226 (10%) Query: 602 VKSSEPVKETVQTTQSPTPVEKETVVTTQAEVFP-PPVAMLQIPVAPAVPTVS------- 653 V S P + + +P P + +V P PP + P A P V Sbjct: 706 VPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPP 765 Query: 654 -LVPPAFPVSMPV-----PPPGFSPIPPPPFLRASFNPSQPPPGFMP------PPVPPPV 701 VPP+ P S+P+ PPP P P L+A +P PG P P+ P Sbjct: 766 LQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 825 Query: 702 VPPPTIPPVVPTSLVQ--PSLSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNA 759 PPP PPV+ L+Q PS +P T++ P SV+ T AL G Sbjct: 826 TPPPQAPPVLAAPLLQVPPSPPASP-TLQAPRRPPTPGPDTSVSGPRLTLALAPGPP-PP 883 Query: 760 PTKQAEPEEKVPHLIDHQISSGENTRSVIPNDISSNAAILGGQPPN 805 P++ P L H S+ + D PP+ Sbjct: 884 PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPD 929 Score = 42.0 bits (97), Expect = 0.004 Identities = 87/403 (21%), Positives = 135/403 (33%), Gaps = 70/403 (17%) Query: 681 ASFNPSQPPPGFMPP-PVPPPVVPPPTIPPVVPTSLVQPSLSMTPETVKDVGFGSLVIP- 738 A+ P+ PG + P P P PPP P + ++ P + G G IP Sbjct: 13 AARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPE 72 Query: 739 ----------GGSVASNLATSALPAGNVFNA-PTKQAEP-------------------EE 768 G+ + N A+ +G A P K P ++ Sbjct: 73 SAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQK 132 Query: 769 KVPHLIDHQISSGENTRSVIPNDISSNAAILGGQPPNVTSNSGI----------LGVQRP 818 + + ++ G+ T + + +S+ A P T + + +G+ RP Sbjct: 133 GLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRP 192 Query: 819 NVSSNSEILGVRP-SNVSSSSGIIAAQPPNILNN--SGILGIQPPSVSNSSGLLGVLPPN 875 S+ P +VSS+S +P S G+Q P+ + S P + Sbjct: 193 APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS--SATPLS 250 Query: 876 IPNNSGLVGVQPPNVPNTPGLLGTQP-PAGPQNLPPLSIPNQRMPTMPMLDIRPGLIPQA 934 P SG P P P +QP P G Q L P + R P L Sbjct: 251 SPARSGPSARGTPRAPAHP----SQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLAT 306 Query: 935 PGPRFPLIQPGIPPQRG-------IPPPSVLDSALHPPPRGPFPPGDIFSQPERPFLAPG 987 P P +P PP +PP L + L P P P + + P P P Sbjct: 307 PSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPP-ATPP 365 Query: 988 RQSVDNVTNPEKRIPLGNDNIQQEGDRDYRFPPIETRESISRP 1030 Q+ ++T P + P I PPI+ S++ P Sbjct: 366 SQAPPSMTTPPMQAPPSLQTI----------PPIQVPHSLTSP 398 >gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] Length = 2217 Score = 80.1 bits (196), Expect = 1e-14 Identities = 109/430 (25%), Positives = 156/430 (36%), Gaps = 43/430 (10%) Query: 594 TVNTEWETVKSSEPVKETVQTTQSP-----TPVEKETVVTTQAEVFPPPVAMLQIPVAPA 648 TV ++ ++ + S + SP +P E V Q+ P A Q AP Sbjct: 623 TVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQS--LPSLGAYQQPTAAPG 680 Query: 649 VPTVSLVPPAFPVSM----PVPPPGFSPIPPPPFLRASFNPSQP-PPGFMPPPVPPPVVP 703 +P S+ PA P S+ P P F+P+ PPP P QP PPG PPP+ P Sbjct: 681 LPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPL 740 Query: 704 PPTIPP--VVPTSLVQPSLSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPT 761 P + P VVP V P L VG + + P L P + P Sbjct: 741 PQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKP-------LQMPQAPLQPLAQVPP 793 Query: 762 KQAEPEEKVPHLIDHQISSGENTRSVIPNDISSNAAILGGQPPNVTSNSGILGVQRPNVS 821 Q P VP + ++ + +P+ A + PP S + IL + Sbjct: 794 -QMPPIPVVPPITP--LAGIDGLPPALPD--LPTATVPPVPPPQYFSPAVILPSLAAPLP 848 Query: 822 SNSEILGVRPSNVSSSSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSG 881 S L ++ + G A P + P+ + LL V PP + S Sbjct: 849 PASPALPLQAVKLPHPPGAPLAMPCRTI---------VPNAPATIPLLAVAPPGVAALS- 898 Query: 882 LVGVQPPNVPNTPGLLGTQPPAGPQNLPPL---SIPNQRM-PTMPMLDIRPGLIPQAPGP 937 + +P P P P ++PP ++ N R P P L +P L PQ P Sbjct: 899 -IHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLP 957 Query: 938 RFPLI--QPGIPPQRGIPPPSVLDSALHPPPRGPFPPGDIFSQPERPFLAPGRQSVDNVT 995 P + QP +PPQ PP VL PP+ PP P + Sbjct: 958 PQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAA 1017 Query: 996 NPEKRIPLGN 1005 P +I LG+ Sbjct: 1018 TPGSQILLGH 1027 Score = 40.0 bits (92), Expect = 0.014 Identities = 109/468 (23%), Positives = 157/468 (33%), Gaps = 68/468 (14%) Query: 610 ETVQTTQSPTPVEKETVVTTQAEVFPP-PVAMLQIPVAPA----VPTVSLVPPAFPVSMP 664 E + +Q+ PV ++ V+ T F PVA P AP +P SL P A S P Sbjct: 1289 EESRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAPEAPESSPPLPLSSLPPEASQDSAP 1348 Query: 665 VPPPGFSPIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPPPTIPPV--VPTSLVQPSLSM 722 S P FL + SQ P PP PP P+ PPV +P P+ S Sbjct: 1349 YKDQ-LSSKEQPSFLASQQLLSQAGPS--NPPGAPPAPLAPSSPPVTALPQDGAAPATST 1405 Query: 723 TPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDHQISSGE 782 PE P AS P G T Q E L + G Sbjct: 1406 MPE------------PASGTASQAGGPGTPQGLTSELETSQPLAETHEAPLAVQPLVVGL 1453 Query: 783 NTRSVIPNDISSNAAILGGQP--PNVTSNSGILGVQRPNVSSNSEILGVRPSNVSSSSG- 839 + P S+ A +P P S G +P + + +L VS ++ Sbjct: 1454 APCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQ 1513 Query: 840 --------IIAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVP 891 + QPP+ L + G PP V + L + + +VP Sbjct: 1514 LPSPPLGPTVPPQPPSALESDG--EGPPPRVGFVDSTIKSLDEKLRTL-----LYQEHVP 1566 Query: 892 NTPGLLGTQPPAGPQN--LPPLSIPNQRMPTMPMLDIRPGLIPQAPGPRFPLIQPGIPPQ 949 + GT G ++ L PL P ++ G + P P+ + + Sbjct: 1567 TSSASAGTPVEVGDRDFTLEPLR------GDQPRSEVCGGDLALPPVPK-----EAVSGR 1615 Query: 950 RGIPPPSVLDSALHPPPRGPFPPGDIFSQPERP-------FLAPGRQSVDN---VTNPEK 999 +P P V S L P G S + GRQ + V + + Sbjct: 1616 VQLPQPLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQ 1675 Query: 1000 RIPLGNDNIQQEG-DRDYRFPPIETRESISRPPPVDVRDVVGRPIDPR 1046 +P + E DRD E ES + PPP D+ V G+ P+ Sbjct: 1676 DVPAFVRPARVEPTDRDGG----EAGESSAEPPPSDMGTVGGQASHPQ 1719 Score = 39.7 bits (91), Expect = 0.019 Identities = 55/203 (27%), Positives = 74/203 (36%), Gaps = 32/203 (15%) Query: 617 SPTPVEKETVVTTQAEVFPPPVAMLQIPVAPAVPTVSLVPPAFPVSMPVPPPGFSPIPPP 676 SP + T PP + PV P PT +PP PV PP P PP Sbjct: 927 SPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPT---LPP-----QPVLPP--QPTRPP 976 Query: 677 PFLRASFNPSQPPPGFMPPPVPPPVVPPPTIPPVVPTSLVQPSLSMTPETVKDVGF-GSL 735 P PP +P P PV+PP PV P L QP L PE GS Sbjct: 977 -------QPVLPPQPMLP---PQPVLPPQPALPVRPEPL-QPHL---PEQAAPAATPGSQ 1022 Query: 736 VIPGG------SVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDHQISSGENTRSVIP 789 ++ G VA+ + T +P V + P + P L+ SS + + Sbjct: 1023 ILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEV-LLPAAPELLPQFPSSLATVSASVQ 1081 Query: 790 NDISSNAAILGGQPPNVTSNSGI 812 + + A +L P + GI Sbjct: 1082 SVPTQTATLLPPANPPLPGGPGI 1104 Score = 35.0 bits (79), Expect = 0.46 Identities = 43/167 (25%), Positives = 60/167 (35%), Gaps = 22/167 (13%) Query: 611 TVQTTQS--PTPVEKETVVTTQAEVFPPPVAMLQIPVAPAVPTVSLVPPAFPVSMPVPPP 668 TVQ ++ P P V PP + PV P PT P P M P P Sbjct: 931 TVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQP 990 Query: 669 GFSPIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPPPTI------PPVVPTSLVQPSLSM 722 +PP P L P QP +P P P I P V + P++ + Sbjct: 991 ---VLPPQPALPVRPEPLQP---HLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPV 1044 Query: 723 TPETVKDVGFGSLVIPGG-----SVASNLATSALPAGNVFNAPTKQA 764 P V +++P S+LAT + +V + PT+ A Sbjct: 1045 PPAAVLSPPLPEVLLPAAPELLPQFPSSLAT---VSASVQSVPTQTA 1088 >gi|47132519 Ras association and pleckstrin homology domains 1 isoform 1 [Homo sapiens] Length = 1250 Score = 77.4 bits (189), Expect = 8e-14 Identities = 103/401 (25%), Positives = 147/401 (36%), Gaps = 85/401 (21%) Query: 672 PIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPPPTIPPVVPTSLVQPSLSMTPETVKDVG 731 P+ P P + + SQP P PPP PPP PPP PP P + ++ G Sbjct: 608 PLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPP---------LPSQSAPSAG 658 Query: 732 FGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDHQISSGENTRSVIPND 791 + + S + L ++ +G +F PT P ++ Q SV P Sbjct: 659 SAAPMFVKYSTITRLQNASQHSGALFKPPT---------PPVMQSQ--------SVKPQI 701 Query: 792 ISSNAAILGGQPPNVTSNSGILGVQRPNVSSNSEILGVRPSNVSSSSGIIAAQPP--NIL 849 + ++ PP P + S + ++P+ + S +A PP I Sbjct: 702 LVPPNGVVPPPPP-----------PPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIH 750 Query: 850 NNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGLLGTQPPAGPQNLP 909 I + PP+ + LPP P LV + P T + TQ A P P Sbjct: 751 QVQHITQVAPPTPPPPPPIPAPLPPQAPPKP-LVTIPAPTSTKTVAPVVTQ-AAPPTPTP 808 Query: 910 PLSIPNQRMPTMPMLDIRPGLIPQAPGPRFPLIQPGIPPQRGI---PPPSVLD------- 959 P+ P ++ P P I P P P P+ P +P Q+ PPPS L Sbjct: 809 PVP-PAKKQPAFPASYIP----PSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVK 863 Query: 960 --SALHPPPRGPFPPGDIFSQPERPFLA-PGRQSVDNVTNPEK----RIPLGNDNIQQEG 1012 ++ PPP P PP + SQP +P A QS V K IP+ + + Sbjct: 864 QIASQFPPP--PTPPA-MESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPD----- 915 Query: 1013 DRDYRFPPIETRESISRPPPVDVRDVVGRPIDPREGPGRPP 1053 FPP S+ PPP P P P PP Sbjct: 916 -----FPPPPPESSLVFPPP---------PPSPVPAPPPPP 942 Score = 56.6 bits (135), Expect = 1e-07 Identities = 113/505 (22%), Positives = 169/505 (33%), Gaps = 112/505 (22%) Query: 605 SEPVKETVQTTQSPTPVEKETVVTTQAEVFPP--PVAMLQIPVAPAVPTVSLVPPAFPVS 662 SE K Q +S + E++ + PP P + P + P+ L PP P Sbjct: 578 SEAWKRGTQLEES-SKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPP 636 Query: 663 MPVPPPGFSPIPPPP---------------FLRASF-----NPSQPPPGFMPPPVPP--- 699 P PPP P PPPP F++ S N SQ PP PP Sbjct: 637 PPPPPP---PPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQ 693 Query: 700 -------------PVVPPPTIPPVVPTSLVQPSLSMTPETVKDVGFGSLVIPGGSVASNL 746 VVPPP PP PT PG ++A Sbjct: 694 SQSVKPQILVPPNGVVPPPPPPPPPPT------------------------PGSAMAQLK 729 Query: 747 ATSALPAGNVFNAPTKQAEPEEKVPHLIDHQISSGENTRSVIPNDISSNAAILGGQPPNV 806 P+ F+AP P L HQ+ ++ V P I PP Sbjct: 730 PAPCAPSLPQFSAPP---------PPLKIHQV---QHITQVAPPTPPPPPPIPAPLPPQA 777 Query: 807 TSNSGILGVQRPNVSSNSEILGVRPSNVSSSSGIIAAQPPNILNNSGILGIQPPSVSNSS 866 ++ + P + + + + + + + A+ S I PPS Sbjct: 778 PPKP-LVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYI----PPSPPTPP 832 Query: 867 GLLGVLPPNIPNNSGLVGVQPPN----VPNTPGLLGTQPPAGPQNLPPLSIPNQRMPTMP 922 + V PP +P PP+ VP+ + +Q P P PP M + P Sbjct: 833 --VPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFP--PPPTPP------AMESQP 882 Query: 923 MLDIRPGLIPQAPG--PRFPLIQP-GIP-PQRGIPPPSVLDSALHPP------PRGPFPP 972 + + + PQ+P P QP IP P PPP S + PP P P PP Sbjct: 883 LKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPP 942 Query: 973 GDIFSQPERPFLAPGRQSVDNVTNPEKR---IPLGNDNIQQEGDRDYRFPPIETRESI-- 1027 S +PG+++ + K+ P N +I+ ++ P + +S+ Sbjct: 943 PPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVS 1002 Query: 1028 SRPPPVDVRDVVGRPIDPREGPGRP 1052 PP + + P P +P Sbjct: 1003 KFTPPAESGSPSKETLPPPAAPPKP 1027 Score = 56.6 bits (135), Expect = 1e-07 Identities = 78/329 (23%), Positives = 113/329 (34%), Gaps = 54/329 (16%) Query: 607 PVKETVQTTQSPTPVEKETVVTTQ-AEVFPPPV---AMLQIPVAP--------AVPTVSL 654 P +++ P+P+ V Q A FPPP AM P+ P + P V Sbjct: 841 PKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKA 900 Query: 655 VPPAFPVSMPVPPPGFSPIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPP---------- 704 P P S+PVP P F PPPP F P P P PPP PPP P Sbjct: 901 KPKWQPSSIPVPSPDFP--PPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGK 958 Query: 705 PTIPPVVPTSLVQPSLSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQA 764 T P P ++K P +L + P +P+K+ Sbjct: 959 KTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAE-SGSPSKET 1017 Query: 765 EPEEKVPHLIDHQISSGENTRSVIPND-ISSNAAILGGQ------------------PPN 805 P P SG N V+ +S+ A +L G+ PP Sbjct: 1018 LPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPP 1077 Query: 806 VTSNSGILGVQRP-----NVSSNSEILGVRPSNVSSSSGIIAAQPPNILNNSGILGIQPP 860 + + ++ P N S ++ +P S S + A PP + + Sbjct: 1078 PETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMS-VKKAPPPTRPKRNDSTRLTQA 1136 Query: 861 SVSNSSGLLGVLP--PNIPNNSGLVGVQP 887 +S + V+P P P +S + VQP Sbjct: 1137 EISEQPTMATVVPQVPTSPKSS--LSVQP 1163 Score = 47.8 bits (112), Expect = 7e-05 Identities = 108/474 (22%), Positives = 158/474 (33%), Gaps = 91/474 (19%) Query: 606 EPVKETVQTTQSPTP---VEKETVVTTQAEVFPPPV---AMLQIPVAPAVPTVSLVPPAF 659 +P V +QS P V VV PPP AM Q+ AP P++ Sbjct: 685 KPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSL------- 737 Query: 660 PVSMPVPPPGFSPIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPPPTIPPVVPTSLVQPS 719 P FS PPP + + +Q P PPP P P PP PP ++ P+ Sbjct: 738 --------PQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPT 789 Query: 720 LSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDHQIS 779 + T + + T A P PT P +K P I Sbjct: 790 STKT-------------------VAPVVTQAAPP-----TPTPPVPPAKKQPAFPASYIP 825 Query: 780 SGENTR--SVIPNDISSNAAILGGQPPN----VTSNSGILGVQRP----NVSSNSEILGV 829 T V P + + PP+ V S + Q P + S+ L Sbjct: 826 PSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKP 885 Query: 830 RPSNVS-SSSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQPP 888 P+NV+ S + A+P ++ + P S L+ PP P V PP Sbjct: 886 VPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSP-----VPAPPP 940 Query: 889 NVPNTPGLLGTQPPAGPQNLPPLSIPNQRMPTMPMLDIRPGLIPQAPGPRFPLIQPGIPP 948 P T + + + S P + P P R I + G P P Sbjct: 941 PPPPTASPTPDKSGSPGKKTSKTSSPGGKKP--PPTPQRNSSIKSSSGAEHP------EP 992 Query: 949 QRGIPPPSVLDSALHPPPRGPFPPGDIFSQPERPFLAPGRQSVDNVTNP--------EKR 1000 +R P L S PP P + P P PG+ ++ V P + Sbjct: 993 KR--PSVDSLVSKFTPPAESGSPSKETLPPPAAP-PKPGKLNLSGVNLPGVLQQGCVSAK 1049 Query: 1001 IPL----GNDNIQQ----EGDRDYRFPPIETRESISRPPPVDVRDVVGRPIDPR 1046 P+ G D++ + D D+ PP ET + PP+++ V P+ Sbjct: 1050 APVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPL---PPIEIPAVFSGNTSPK 1100 >gi|160707881 formin 2 [Homo sapiens] Length = 1722 Score = 72.0 bits (175), Expect = 3e-12 Identities = 105/391 (26%), Positives = 137/391 (35%), Gaps = 62/391 (15%) Query: 618 PTPVEKETVVTTQAEVFPPPVAMLQIPVAPAVPTVSLVPPAFPVSMPVPPP--GFSPIPP 675 P P+ TV T + P P + + P P PP +P PPP G +P Sbjct: 880 PPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPP-----PPLPGAGIPPPPPLPGAGILPL 934 Query: 676 PPFLRASFNPSQPPPGFMPPPVPPPVVPPPTIPPVVPTSLVQPSLSMTPETVKDVGF-GS 734 PP A P P PG PP PP +PP +P + + P P + G Sbjct: 935 PPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPP-----PPPLPGAGIPPP 989 Query: 735 LVIPGGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDHQISSGENTRSVIPNDISS 794 +PG + LP + P P L +G +P Sbjct: 990 PPLPGAGIP---PPPPLPGAGIPPPPPLPGAGIPPPPPL----PGAGIPPPPPLPG---- 1038 Query: 795 NAAILGGQPPNVTSNSGI--------LGVQRPNVSSNSEILGVRPSNVSSSSGIIAAQPP 846 G PP +GI G+ P + G+ P +GI PP Sbjct: 1039 ----AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA---GIPPPPPLPGAGI---PPP 1088 Query: 847 NILNNSGI--------LGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGLLG 898 L +GI +GI PP +G+ PP +P G+ PP P PG Sbjct: 1089 PPLPGAGIPPPPPLPGVGIPPPPPLPGAGI--PPPPPLPG----AGIPPP--PPLPGAGI 1140 Query: 899 TQPPAGPQ--NLPPLSIPNQRMPTMPMLDIRPGLIPQAPGPRFPLIQPGIPPQRGIPPPS 956 PP P+ PP +P +P P L G+ P P P + P P GIPPP Sbjct: 1141 PPPPPLPRVGIPPPPPLPGAGIPPPPPLP-GAGIPPPPPLPGVGIPPPPPLPGVGIPPPP 1199 Query: 957 VLDSALHPPPRGPFPPGDIFSQPERPFLAPG 987 L A PPP P P I P P PG Sbjct: 1200 PLPGAGIPPP-PPLPGMGIPPAPAPPLPPPG 1229 Score = 70.5 bits (171), Expect = 1e-11 Identities = 98/362 (27%), Positives = 129/362 (35%), Gaps = 65/362 (17%) Query: 635 PPPVAMLQIPVAPAVPTVSLVPP----AFPVSMPVPPPGFSPIPPPPFLRASFNPSQPPP 690 PPP+ IP+ P +P + PP + P P PG PPPP A P P P Sbjct: 956 PPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1015 Query: 691 GF-MPPPVPPP---VVPPPTIPPV-VPTSLVQPSLSMTPETVKDVGFGSLVIPGGSVASN 745 G +PPP P P + PPP +P +P P + P +PG + Sbjct: 1016 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP---------LPGAGIPP- 1065 Query: 746 LATSALPAGNVFNAPTKQAEPEEKVPHLIDHQISSGENTRSVIPNDISSNAAILGGQPPN 805 LP + P P L +G +P +G PP Sbjct: 1066 --PPPLPGAGIPPPPPLPGAGIPPPPPLP----GAGIPPPPPLPG--------VGIPPPP 1111 Query: 806 VTSNSGILGVQRPNVSSNSEILGVRPSNVSSSSGIIAAQPPNILNNSGI--------LGI 857 +GI P + G+ P +GI PP L GI GI Sbjct: 1112 PLPGAGI--PPPPPLPG----AGIPPPPPLPGAGI---PPPPPLPRVGIPPPPPLPGAGI 1162 Query: 858 QPPSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGLLGTQPPA---GPQNLPPLSIP 914 PP +G+ PP +P VG+ PP P PG+ G PP G PP +P Sbjct: 1163 PPPPPLPGAGIPP--PPPLPG----VGIPPP--PPLPGV-GIPPPPPLPGAGIPPPPPLP 1213 Query: 915 NQRMPTMPMLDIRPGLIPQAPGPRFPLIQPGIPPQRG---IPPPSVLDSALHPPPRGPFP 971 +P P + P P P P+ P + PQ G +P P V P P G F Sbjct: 1214 GMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLPSGLFG 1273 Query: 972 PG 973 G Sbjct: 1274 LG 1275 Score = 68.9 bits (167), Expect = 3e-11 Identities = 112/419 (26%), Positives = 156/419 (37%), Gaps = 67/419 (15%) Query: 583 GFAEGGMIDQETVNTEWETVKSSEPVKETVQTTQSPTPVEKETVVTTQAEVFPPPVAMLQ 642 G + G +++TE++T + P+P + T++ P + M+ Sbjct: 821 GQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSP---PPLPCTESSSSMPGLGMVP 877 Query: 643 IPVAPAVPTVSLVPPAFPVSMPVPPP--GFS--PIPPPPFLRASFNPSQPPP--GFMP-P 695 P P +P ++ VP ++P PPP G P PPPP A P P P G +P P Sbjct: 878 -PPPPPLPGMT-VPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLP 935 Query: 696 PVPPPVVPPPTIPPVVPTSLVQPSLSMTPETVKDVGFG-SLVIPGGSVASNLATSALPAG 754 P+P +PP PP +P + + P P + G +PG + LP Sbjct: 936 PLPGAGIPP---PPPLPGAAIPP-----PPPLPGAGIPLPPPLPGAGIP---PPPPLPGA 984 Query: 755 NVFNAPTKQAEPEEKVPHLIDHQISSGENTRSVIPNDISSNAAILGGQPPNVTSNSGILG 814 + P P L +G +P G PP +GI Sbjct: 985 GIPPPPPLPGAGIPPPPPL----PGAGIPPPPPLPG--------AGIPPPPPLPGAGI-- 1030 Query: 815 VQRPNVSSNSEILGVRPSNVSSSSGIIAAQPPNILNNSGI--------LGIQPPSVSNSS 866 P + G+ P +GI PP L +GI GI PP + Sbjct: 1031 PPPPPLPG----AGIPPPPPLPGAGI---PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 1083 Query: 867 GLLGVLPPNIPNNSGLVGVQPPNVPNTPGLLGTQPP---AGPQNLPPLSIPNQRMPTMPM 923 G+ PP +P G+ PP P PG +G PP G PP +P +P P Sbjct: 1084 GI--PPPPPLPG----AGIPPP--PPLPG-VGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1134 Query: 924 LDIRPGLIPQAPGPRFPLIQPGIPPQRGIPPPSVLDSALHPPPRGPFPPGDIFSQPERP 982 L G+ P P PR + P P GIPPP L A PPP P P I P P Sbjct: 1135 LP-GAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPP-PPLPGVGIPPPPPLP 1191 Score = 65.9 bits (159), Expect = 2e-10 Identities = 119/444 (26%), Positives = 154/444 (34%), Gaps = 96/444 (21%) Query: 635 PPPVAMLQIPVAPAVPTVSLVPPAFPV--SMPVPPPGFSPIPPPPFLRASFNPSQPPPGF 692 PPP+ + + ++P + +VPP P M VP + IP PP L+ + PPP Sbjct: 858 PPPLPCTES--SSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGT--EMLPPP-- 911 Query: 693 MPPPVPPPVVPPPTIPPVVPTSLVQPSLSMTPETVKDVGFGSLVIPGGSVASNLATSALP 752 PPP+P +PPP P +P G G L +P A LP Sbjct: 912 -PPPLPGAGIPPP---PPLP------------------GAGILPLPPLPGAGIPPPPPLP 949 Query: 753 AGNVFNAPTKQAEPEEKVPHLIDHQISSGENTRSVIPNDISSNAAILGGQPPNVTSNSGI 812 + P P +P +P + G PP +GI Sbjct: 950 GAAI---PPPPPLPGAGIP----------------LPPPLPG----AGIPPPPPLPGAGI 986 Query: 813 LGVQRPNVSSNSEILGVRPSNVSSSSGIIAAQPPNILNNSGI--------LGIQPPSVSN 864 P + G+ P +GI PP L +GI GI PP Sbjct: 987 --PPPPPLPG----AGIPPPPPLPGAGI---PPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1037 Query: 865 SSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGLLGTQPPA---GPQNLPPLSIPNQRMPTM 921 +G+ PP +P G+ PP P PG G PP G PP +P +P Sbjct: 1038 GAGIPP--PPPLPG----AGIPPP--PPLPGA-GIPPPPPLPGAGIPPPPPLPGAGIPPP 1088 Query: 922 PMLDIRPGLIPQAPGPRFPLIQPGIPPQRGIPPPSVLDSALHPPPRGPFPPGDIFSQPER 981 P L G+ P P P + P P GIPPP L A PPP P P I P Sbjct: 1089 PPLP-GAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPP-PLPGAGIPPPPPL 1146 Query: 982 PFLA-PGRQSVDNVTNPEKRIPLGNDNIQQEGDRDYRFPPIETRESISRPPPVDVRDVVG 1040 P + P + P PL I PP + PPP + V Sbjct: 1147 PRVGIPPPPPLPGAGIPPPP-PLPGAGI----------PPPPPLPGVGIPPPPPLPGVGI 1195 Query: 1041 RPIDPREGPGRPPLDGRDHFGRPP 1064 P P G G PP G PP Sbjct: 1196 PPPPPLPGAGIPPPPPLPGMGIPP 1219 Score = 56.6 bits (135), Expect = 1e-07 Identities = 105/409 (25%), Positives = 136/409 (33%), Gaps = 67/409 (16%) Query: 699 PPVVPPPTIPPVVPTSLVQPSLSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFN 758 PPV P PP P + P E V + + S + S P Sbjct: 758 PPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSLL 817 Query: 759 APTKQAEPEEKVPHLI--------DHQISSGENTRSVIPN-------DISSNAAILGGQP 803 Q +P + PH I +H +SS IP+ + SS+ LG P Sbjct: 818 WSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVP 877 Query: 804 PNVTSNSGIL-------GVQRPNVSSNSEILGVRPSNVSSSSGIIAAQPPNILNNSGIL- 855 P G+ + +P +E+L P + + PP L +GIL Sbjct: 878 PPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAG----IPPPPPLPGAGILP 933 Query: 856 -------GIQPPSVSNSSGL--------LGV-LPPNIPNNSGLVGVQPPNVPNTPGLLGT 899 GI PP + + G+ LPP +P G+ PP P PG G Sbjct: 934 LPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPG----AGIPPP--PPLPGA-GI 986 Query: 900 QPPA---GPQNLPPLSIPNQRMPTMPMLDIRPGLIPQAPGPRFPLIQPGIPPQRGIPPPS 956 PP G PP +P +P P L G+ P P P + P P GIPPP Sbjct: 987 PPPPPLPGAGIPPPPPLPGAGIPPPPPLP-GAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1045 Query: 957 VLDSALHPPPRGPFPPGDIFSQPERPFLA-PGRQSVDNVTNPEKRIPLGNDNIQQEGDRD 1015 L A PPP P P I P P P + P PL I Sbjct: 1046 PLPGAGIPPP-PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP-PLPGAGI------- 1096 Query: 1016 YRFPPIETRESISRPPPVDVRDVVGRPIDPREGPGRPPLDGRDHFGRPP 1064 PP + PPP + P P G G PP G PP Sbjct: 1097 ---PPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1142 >gi|16554449 zonadhesin isoform 3 [Homo sapiens] Length = 2812 Score = 71.6 bits (174), Expect = 4e-12 Identities = 82/392 (20%), Positives = 142/392 (36%), Gaps = 63/392 (16%) Query: 591 DQETVNTEWETVKSSEPVKETVQTTQSPT----PVEKETVVTTQAEV--FPPPVAMLQIP 644 ++ T++TE TV + EP T +TT S P EK ++ T + + P ++M + Sbjct: 645 EKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704 Query: 645 VAPAVPTVSLVPPAFPVSMPVPPPGFSPIPPP-----------PFLRASFNPSQPPPGFM 693 ++ PT+S P P P P S I P P + + +P +P Sbjct: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTE 764 Query: 694 PPPVPP---------PVVPP--PTIP----------PVVPT-----SLVQPSLSM----- 722 P + P P +P PTIP P PT S +PS+ M Sbjct: 765 KPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTL 824 Query: 723 -TPETVKDV-----GFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDH 776 T ET V L IP + +P +P K P EK+ Sbjct: 825 PTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT----- 879 Query: 777 QISSGENTRSVIPNDISSNAAILGGQPPNVTSNSGILGVQRPNVSSNSEILGVRPSNVSS 836 I + + T + IS+ + + P ++ + ++P + + + + +S+ Sbjct: 880 -IPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTIST 938 Query: 837 SSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGL 896 I + P I + + P++S + IP + + P +P T L Sbjct: 939 EKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP-TEKL 997 Query: 897 LGTQPPAGPQNLPPLS--IPNQRMPTMPMLDI 926 +PP L+ + + P+ PM + Sbjct: 998 TALRPPHPSPTATGLAALVMSPHAPSTPMTSV 1029 Score = 54.3 bits (129), Expect = 7e-07 Identities = 61/331 (18%), Positives = 118/331 (35%), Gaps = 27/331 (8%) Query: 726 TVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDHQISSGENTR 785 T V G ++I G+ + P +P P E + IS+ + T Sbjct: 518 TASVVAMGFILINPGTCPVKVLPELPPV-----SPVSSTGPSETTGLTENPTISTKKPTV 572 Query: 786 SVIPNDISSNAAILGGQPPNVTSNSGILGVQRPNVSSNSEILGVRPSNVSSSSGIIAAQP 845 S+ +++ + + P + + + ++P + S + + S I + Sbjct: 573 SIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEK 632 Query: 846 PNILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGLLGTQPPAGP 905 P I + + + P++S + P P ++ P +P + T+ P+ P Sbjct: 633 PTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIP 692 Query: 906 QNLPPLSIPNQRMPTMPMLDIRPGLIPQAPGPRFPLIQPGIPPQRGIPPPSVLDSALHPP 965 P +S+ + T +P + P+ P P +P IP ++ P + P Sbjct: 693 TEKPTISMEETIISTE-----KPTISPEK--PTIPTEKPTIPTEKSTISP---EKPTTPT 742 Query: 966 PRGPFPPGDIFSQPERPFLAPGRQSV--DNVTNPEKR--IPLGNDNIQQEGDRDYRFPPI 1021 + P PE+P + ++ + +T P ++ IP I E P I Sbjct: 743 EKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEK------PTI 796 Query: 1022 ETRESISRPPPVDVRDVVGRPIDPREGPGRP 1052 T E + P + +P P E P P Sbjct: 797 STEEPTT--PTEETTISTEKPSIPMEKPTLP 825 Score = 48.5 bits (114), Expect = 4e-05 Identities = 51/267 (19%), Positives = 98/267 (36%), Gaps = 24/267 (8%) Query: 700 PVVPPPTIPPVVPTSLVQPS--LSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVF 757 PV P +PPV P S PS +T ++ I SV + T + Sbjct: 535 PVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTI- 593 Query: 758 NAPTKQAEPEEKVPHLIDHQISSGENTRSVIPND---ISSNAAILGGQPPNVTSNSGILG 814 PT++ + P I + + + + IP++ I + + + P + S + Sbjct: 594 --PTEKPTISTEKP-TIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTIS 650 Query: 815 VQRPNVSSNSEILGVRPSNVSSSSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPP 874 ++P V + + S +I + P+I + + P++S ++ P Sbjct: 651 TEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKP 710 Query: 875 NIPNNSGLVGVQPPNVPNTPGLLGTQPPAGPQNLPPLSIPNQR------MPTMPMLDIRP 928 I + + P +P + + P P P +IP ++ PT P +P Sbjct: 711 TISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKP--TIPTEKPTISPEKPTTP--TEKP 766 Query: 929 GLIPQ-----APGPRFPLIQPGIPPQR 950 + P+ P P +P IP ++ Sbjct: 767 TISPEKLTIPTEKPTIPTEKPTIPTEK 793 Score = 45.8 bits (107), Expect = 3e-04 Identities = 77/398 (19%), Positives = 127/398 (31%), Gaps = 90/398 (22%) Query: 588 GMIDQETVNTEWETVKSSEPVKETVQTTQSPT-PVEKETVVTTQAEVFPPPVAMLQIPVA 646 G+ + T++T+ TV +P TT+ PT P EK T+ T + Sbjct: 558 GLTENPTISTKKPTVSIEKPSV----TTEKPTVPKEKPTIPTEK---------------- 597 Query: 647 PAVPTVSLVPPAFPVSMPVPPPGFSPIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPPPT 706 PT+S P P P P IP S+ P P P PT Sbjct: 598 ---PTISTEKPTIPSEKPNMPSEKPTIP-----------SEKPTILTEKPTIPS--EKPT 641 Query: 707 IPPVVPTSLVQPSLSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEP 766 IP PT + T E P +++ +P K + P Sbjct: 642 IPSEKPTISTEKPTVPTEEPTT---------PTEETTTSMEEPVIPTEKPSIPTEKPSIP 692 Query: 767 EEKVPHLIDHQISSGENTRSVIPNDISSNAAILGGQPPNVTSNSGILGVQRPNVSSNSEI 826 EK IS I+ + P ++ + ++P + + Sbjct: 693 TEKPT--------------------ISMEETIISTEKPTISPEKPTIPTEKPTIPTEKST 732 Query: 827 LGVRPSNVSSSSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQ 886 + + I + P I + P++S + P IP + + Sbjct: 733 ISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTE 792 Query: 887 PPNV----PNTP---GLLGTQPPAGPQNLPPL------------SIPNQRMPTMPMLDIR 927 P + P TP + T+ P+ P P L +I +++ T+PM + Sbjct: 793 KPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKL-TIPM--EK 849 Query: 928 PGLIPQAPGPRFPLIQPGIPPQRGIPPPSVLDSALHPP 965 P + + P P +P I P++ P L P Sbjct: 850 PTISTEK--PTIPTEKPTISPEKLTIPTEKLTIPTEKP 885 >gi|27881494 zonadhesin isoform 6 [Homo sapiens] Length = 2721 Score = 71.6 bits (174), Expect = 4e-12 Identities = 82/392 (20%), Positives = 142/392 (36%), Gaps = 63/392 (16%) Query: 591 DQETVNTEWETVKSSEPVKETVQTTQSPT----PVEKETVVTTQAEV--FPPPVAMLQIP 644 ++ T++TE TV + EP T +TT S P EK ++ T + + P ++M + Sbjct: 645 EKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704 Query: 645 VAPAVPTVSLVPPAFPVSMPVPPPGFSPIPPP-----------PFLRASFNPSQPPPGFM 693 ++ PT+S P P P P S I P P + + +P +P Sbjct: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTE 764 Query: 694 PPPVPP---------PVVPP--PTIP----------PVVPT-----SLVQPSLSM----- 722 P + P P +P PTIP P PT S +PS+ M Sbjct: 765 KPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTL 824 Query: 723 -TPETVKDV-----GFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDH 776 T ET V L IP + +P +P K P EK+ Sbjct: 825 PTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT----- 879 Query: 777 QISSGENTRSVIPNDISSNAAILGGQPPNVTSNSGILGVQRPNVSSNSEILGVRPSNVSS 836 I + + T + IS+ + + P ++ + ++P + + + + +S+ Sbjct: 880 -IPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTIST 938 Query: 837 SSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGL 896 I + P I + + P++S + IP + + P +P T L Sbjct: 939 EKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP-TEKL 997 Query: 897 LGTQPPAGPQNLPPLS--IPNQRMPTMPMLDI 926 +PP L+ + + P+ PM + Sbjct: 998 TALRPPHPSPTATGLAALVMSPHAPSTPMTSV 1029 Score = 54.3 bits (129), Expect = 7e-07 Identities = 61/331 (18%), Positives = 118/331 (35%), Gaps = 27/331 (8%) Query: 726 TVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDHQISSGENTR 785 T V G ++I G+ + P +P P E + IS+ + T Sbjct: 518 TASVVAMGFILINPGTCPVKVLPELPPV-----SPVSSTGPSETTGLTENPTISTKKPTV 572 Query: 786 SVIPNDISSNAAILGGQPPNVTSNSGILGVQRPNVSSNSEILGVRPSNVSSSSGIIAAQP 845 S+ +++ + + P + + + ++P + S + + S I + Sbjct: 573 SIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEK 632 Query: 846 PNILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGLLGTQPPAGP 905 P I + + + P++S + P P ++ P +P + T+ P+ P Sbjct: 633 PTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIP 692 Query: 906 QNLPPLSIPNQRMPTMPMLDIRPGLIPQAPGPRFPLIQPGIPPQRGIPPPSVLDSALHPP 965 P +S+ + T +P + P+ P P +P IP ++ P + P Sbjct: 693 TEKPTISMEETIISTE-----KPTISPEK--PTIPTEKPTIPTEKSTISP---EKPTTPT 742 Query: 966 PRGPFPPGDIFSQPERPFLAPGRQSV--DNVTNPEKR--IPLGNDNIQQEGDRDYRFPPI 1021 + P PE+P + ++ + +T P ++ IP I E P I Sbjct: 743 EKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEK------PTI 796 Query: 1022 ETRESISRPPPVDVRDVVGRPIDPREGPGRP 1052 T E + P + +P P E P P Sbjct: 797 STEEPTT--PTEETTISTEKPSIPMEKPTLP 825 Score = 48.5 bits (114), Expect = 4e-05 Identities = 51/267 (19%), Positives = 98/267 (36%), Gaps = 24/267 (8%) Query: 700 PVVPPPTIPPVVPTSLVQPS--LSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVF 757 PV P +PPV P S PS +T ++ I SV + T + Sbjct: 535 PVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTI- 593 Query: 758 NAPTKQAEPEEKVPHLIDHQISSGENTRSVIPND---ISSNAAILGGQPPNVTSNSGILG 814 PT++ + P I + + + + IP++ I + + + P + S + Sbjct: 594 --PTEKPTISTEKP-TIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTIS 650 Query: 815 VQRPNVSSNSEILGVRPSNVSSSSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPP 874 ++P V + + S +I + P+I + + P++S ++ P Sbjct: 651 TEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKP 710 Query: 875 NIPNNSGLVGVQPPNVPNTPGLLGTQPPAGPQNLPPLSIPNQR------MPTMPMLDIRP 928 I + + P +P + + P P P +IP ++ PT P +P Sbjct: 711 TISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKP--TIPTEKPTISPEKPTTP--TEKP 766 Query: 929 GLIPQ-----APGPRFPLIQPGIPPQR 950 + P+ P P +P IP ++ Sbjct: 767 TISPEKLTIPTEKPTIPTEKPTIPTEK 793 Score = 45.8 bits (107), Expect = 3e-04 Identities = 77/398 (19%), Positives = 127/398 (31%), Gaps = 90/398 (22%) Query: 588 GMIDQETVNTEWETVKSSEPVKETVQTTQSPT-PVEKETVVTTQAEVFPPPVAMLQIPVA 646 G+ + T++T+ TV +P TT+ PT P EK T+ T + Sbjct: 558 GLTENPTISTKKPTVSIEKPSV----TTEKPTVPKEKPTIPTEK---------------- 597 Query: 647 PAVPTVSLVPPAFPVSMPVPPPGFSPIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPPPT 706 PT+S P P P P IP S+ P P P PT Sbjct: 598 ---PTISTEKPTIPSEKPNMPSEKPTIP-----------SEKPTILTEKPTIPS--EKPT 641 Query: 707 IPPVVPTSLVQPSLSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEP 766 IP PT + T E P +++ +P K + P Sbjct: 642 IPSEKPTISTEKPTVPTEEPTT---------PTEETTTSMEEPVIPTEKPSIPTEKPSIP 692 Query: 767 EEKVPHLIDHQISSGENTRSVIPNDISSNAAILGGQPPNVTSNSGILGVQRPNVSSNSEI 826 EK IS I+ + P ++ + ++P + + Sbjct: 693 TEKPT--------------------ISMEETIISTEKPTISPEKPTIPTEKPTIPTEKST 732 Query: 827 LGVRPSNVSSSSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQ 886 + + I + P I + P++S + P IP + + Sbjct: 733 ISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTE 792 Query: 887 PPNV----PNTP---GLLGTQPPAGPQNLPPL------------SIPNQRMPTMPMLDIR 927 P + P TP + T+ P+ P P L +I +++ T+PM + Sbjct: 793 KPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKL-TIPM--EK 849 Query: 928 PGLIPQAPGPRFPLIQPGIPPQRGIPPPSVLDSALHPP 965 P + + P P +P I P++ P L P Sbjct: 850 PTISTEK--PTIPTEKPTISPEKLTIPTEKLTIPTEKP 885 >gi|116284398 WAS/WASL interacting protein family, member 1 [Homo sapiens] Length = 503 Score = 69.7 bits (169), Expect = 2e-11 Identities = 91/336 (27%), Positives = 122/336 (36%), Gaps = 70/336 (20%) Query: 656 PPAFPVSMPVPPPGFSPIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPPPTIPPVVPTSL 715 PP+ P PVP PG PP +P MPPP P P +IPP VP+ Sbjct: 143 PPSGPGRFPVPSPGHRSGPP-----------EPQRNRMPPPRPDVGSKPDSIPPPVPS-- 189 Query: 716 VQPSLSMTPETVKDV--GFGSLVIPGG-----------SVASNLATSALPAGNVFNAPTK 762 TP ++ GS +PGG N T AL G++ +P Sbjct: 190 -------TPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGT-ALGGGSIRQSPLS 241 Query: 763 QAEPEEKVPHLIDHQISSGENTRSVIPNDISSNAAI---LGGQPPNVTSNSGILGVQRPN 819 + P P L + ++ P + + +I PP + + RP+ Sbjct: 242 SSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPS 301 Query: 820 VSSNSEILGVRPSNVS------SSSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLGVLP 873 SS + PS SSSG + P + + L P + S G G LP Sbjct: 302 ASSQAPPPPPPPSRPGPPPLPPSSSG--NDETPRLPQRNLSLSSSTPPLP-SPGRSGPLP 358 Query: 874 PNIPNNSGLVGVQPPNVPNTPGLLGTQPPAGPQNLPPLS---IPNQRMPTMPMLDIRPGL 930 P PP V + PG G PP PP+S ++ +P P L R G+ Sbjct: 359 PPPSER------PPPPVRDPPGRSGPLPPP-----PPVSRNGSTSRALPATPQLPSRSGV 407 Query: 931 IPQAPGPRFPLIQPGIPPQRGIPPPSVLDSALHPPP 966 GPR PL P P G PPP PPP Sbjct: 408 DSPRSGPRPPL--PPDRPSAGAPPP--------PPP 433 Score = 47.4 bits (111), Expect = 9e-05 Identities = 61/226 (26%), Positives = 77/226 (34%), Gaps = 34/226 (15%) Query: 864 NSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGLLGTQPPAGPQNLPPLSIPNQRMPTMPM 923 N SG G PP +P +P + P+ PG P G ++ PP N+ P P Sbjct: 119 NDSG--GSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSP-GHRSGPPEPQRNRMPPPRPD 175 Query: 924 LDIRPGLIPQAPGPRFPLIQPGIPPQRGIPPPSVLDSALHPPPRGPFPP----------- 972 + +P IP P P P P RG PP + P GP PP Sbjct: 176 VGSKPDSIPP-PVPSTPRPIQSSPHNRGSPP---VPGGPRQPSPGPTPPPFPGNRGTALG 231 Query: 973 -GDIFSQP--------ERPFLAPGRQSVDNVTNPEKRIPLGN-DNIQQEGDRDYRFPPIE 1022 G I P RP L P + P P+GN +I +E PP Sbjct: 232 GGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPP--PPQN 289 Query: 1023 TRESISRPPPVDVRDVVGRPIDPREGPGRPPL----DGRDHFGRPP 1064 + + P P P PG PPL G D R P Sbjct: 290 NKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLP 335 Score = 41.6 bits (96), Expect = 0.005 Identities = 29/108 (26%), Positives = 44/108 (40%) Query: 619 TPVEKETVVTTQAEVFPPPVAMLQIPVAPAVPTVSLVPPAFPVSMPVPPPGFSPIPPPPF 678 +P+ + + + + P P L P P V P ++P PPP + P P Sbjct: 238 SPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPST 297 Query: 679 LRASFNPSQPPPGFMPPPVPPPVVPPPTIPPVVPTSLVQPSLSMTPET 726 R S + PPP P PP +PP + L Q +LS++ T Sbjct: 298 PRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSST 345 Score = 41.2 bits (95), Expect = 0.006 Identities = 60/184 (32%), Positives = 70/184 (38%), Gaps = 36/184 (19%) Query: 888 PNVPNTPGLLGTQPPAGPQNLPPL--SIPNQRMPTMP-----MLDIRPGLIPQAPGPRFP 940 P P PG GT G PL S P P +P LD +P P G R P Sbjct: 217 PTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNR-P 275 Query: 941 LIQ----PGIPPQRGIPP----PSVLDSALHPPPRGPFPPGDIFSQPERPFLAPGRQSVD 992 I P PPQ PP P S+ PPP P PP S+P P L P D Sbjct: 276 SIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPP--PPPP----SRPGPPPLPPSSSGND 329 Query: 993 NVTN-PEKRIPLGNDN--IQQEGDRDYRFPPIETRESISRPPPVDVRDVVGRPIDPREGP 1049 P++ + L + + G R PP + RPPP VRD G R GP Sbjct: 330 ETPRLPQRNLSLSSSTPPLPSPG-RSGPLPPPPS----ERPPP-PVRDPPG-----RSGP 378 Query: 1050 GRPP 1053 PP Sbjct: 379 LPPP 382 Score = 40.8 bits (94), Expect = 0.008 Identities = 38/121 (31%), Positives = 45/121 (37%), Gaps = 26/121 (21%) Query: 618 PTPVEKETVVTTQAEVFPPPVAMLQIPVAPAVPTVSLV--------PPAFPVSMPVPP-- 667 P PV + E PPP P P+ P S PP+ P P+PP Sbjct: 268 PPPVGNRPSI--HREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSS 325 Query: 668 PGFSPIPPPPFLRASFNPSQPP------PGFMPPP----VPPPVVPPP----TIPPVVPT 713 G P P S + S PP G +PPP PPPV PP +PP P Sbjct: 326 SGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPV 385 Query: 714 S 714 S Sbjct: 386 S 386 Score = 33.5 bits (75), Expect = 1.3 Identities = 29/90 (32%), Positives = 35/90 (38%), Gaps = 5/90 (5%) Query: 1028 SRPP--PVDVRDVVGRPIDPREGPGRPPLDGRDHFGRPPVDIRENLVRPGIDHLGRRDHF 1085 SRPP P R +P P GPGR P+ H PP R + P D + D Sbjct: 124 SRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPD-- 181 Query: 1086 GFNPEKPWGHRGDFDEREHR-VLPVYGGPK 1114 P P R +R PV GGP+ Sbjct: 182 SIPPPVPSTPRPIQSSPHNRGSPPVPGGPR 211 >gi|38373695 WAS/WASL interacting protein family, member 1 [Homo sapiens] Length = 503 Score = 69.7 bits (169), Expect = 2e-11 Identities = 91/336 (27%), Positives = 122/336 (36%), Gaps = 70/336 (20%) Query: 656 PPAFPVSMPVPPPGFSPIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPPPTIPPVVPTSL 715 PP+ P PVP PG PP +P MPPP P P +IPP VP+ Sbjct: 143 PPSGPGRFPVPSPGHRSGPP-----------EPQRNRMPPPRPDVGSKPDSIPPPVPS-- 189 Query: 716 VQPSLSMTPETVKDV--GFGSLVIPGG-----------SVASNLATSALPAGNVFNAPTK 762 TP ++ GS +PGG N T AL G++ +P Sbjct: 190 -------TPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGT-ALGGGSIRQSPLS 241 Query: 763 QAEPEEKVPHLIDHQISSGENTRSVIPNDISSNAAI---LGGQPPNVTSNSGILGVQRPN 819 + P P L + ++ P + + +I PP + + RP+ Sbjct: 242 SSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPS 301 Query: 820 VSSNSEILGVRPSNVS------SSSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLGVLP 873 SS + PS SSSG + P + + L P + S G G LP Sbjct: 302 ASSQAPPPPPPPSRPGPPPLPPSSSG--NDETPRLPQRNLSLSSSTPPLP-SPGRSGPLP 358 Query: 874 PNIPNNSGLVGVQPPNVPNTPGLLGTQPPAGPQNLPPLS---IPNQRMPTMPMLDIRPGL 930 P PP V + PG G PP PP+S ++ +P P L R G+ Sbjct: 359 PPPSER------PPPPVRDPPGRSGPLPPP-----PPVSRNGSTSRALPATPQLPSRSGV 407 Query: 931 IPQAPGPRFPLIQPGIPPQRGIPPPSVLDSALHPPP 966 GPR PL P P G PPP PPP Sbjct: 408 DSPRSGPRPPL--PPDRPSAGAPPP--------PPP 433 Score = 47.4 bits (111), Expect = 9e-05 Identities = 61/226 (26%), Positives = 77/226 (34%), Gaps = 34/226 (15%) Query: 864 NSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGLLGTQPPAGPQNLPPLSIPNQRMPTMPM 923 N SG G PP +P +P + P+ PG P G ++ PP N+ P P Sbjct: 119 NDSG--GSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSP-GHRSGPPEPQRNRMPPPRPD 175 Query: 924 LDIRPGLIPQAPGPRFPLIQPGIPPQRGIPPPSVLDSALHPPPRGPFPP----------- 972 + +P IP P P P P RG PP + P GP PP Sbjct: 176 VGSKPDSIPP-PVPSTPRPIQSSPHNRGSPP---VPGGPRQPSPGPTPPPFPGNRGTALG 231 Query: 973 -GDIFSQP--------ERPFLAPGRQSVDNVTNPEKRIPLGN-DNIQQEGDRDYRFPPIE 1022 G I P RP L P + P P+GN +I +E PP Sbjct: 232 GGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPP--PPQN 289 Query: 1023 TRESISRPPPVDVRDVVGRPIDPREGPGRPPL----DGRDHFGRPP 1064 + + P P P PG PPL G D R P Sbjct: 290 NKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLP 335 Score = 41.6 bits (96), Expect = 0.005 Identities = 29/108 (26%), Positives = 44/108 (40%) Query: 619 TPVEKETVVTTQAEVFPPPVAMLQIPVAPAVPTVSLVPPAFPVSMPVPPPGFSPIPPPPF 678 +P+ + + + + P P L P P V P ++P PPP + P P Sbjct: 238 SPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPST 297 Query: 679 LRASFNPSQPPPGFMPPPVPPPVVPPPTIPPVVPTSLVQPSLSMTPET 726 R S + PPP P PP +PP + L Q +LS++ T Sbjct: 298 PRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSST 345 Score = 41.2 bits (95), Expect = 0.006 Identities = 60/184 (32%), Positives = 70/184 (38%), Gaps = 36/184 (19%) Query: 888 PNVPNTPGLLGTQPPAGPQNLPPL--SIPNQRMPTMP-----MLDIRPGLIPQAPGPRFP 940 P P PG GT G PL S P P +P LD +P P G R P Sbjct: 217 PTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNR-P 275 Query: 941 LIQ----PGIPPQRGIPP----PSVLDSALHPPPRGPFPPGDIFSQPERPFLAPGRQSVD 992 I P PPQ PP P S+ PPP P PP S+P P L P D Sbjct: 276 SIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPP--PPPP----SRPGPPPLPPSSSGND 329 Query: 993 NVTN-PEKRIPLGNDN--IQQEGDRDYRFPPIETRESISRPPPVDVRDVVGRPIDPREGP 1049 P++ + L + + G R PP + RPPP VRD G R GP Sbjct: 330 ETPRLPQRNLSLSSSTPPLPSPG-RSGPLPPPPS----ERPPP-PVRDPPG-----RSGP 378 Query: 1050 GRPP 1053 PP Sbjct: 379 LPPP 382 Score = 40.8 bits (94), Expect = 0.008 Identities = 38/121 (31%), Positives = 45/121 (37%), Gaps = 26/121 (21%) Query: 618 PTPVEKETVVTTQAEVFPPPVAMLQIPVAPAVPTVSLV--------PPAFPVSMPVPP-- 667 P PV + E PPP P P+ P S PP+ P P+PP Sbjct: 268 PPPVGNRPSI--HREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSS 325 Query: 668 PGFSPIPPPPFLRASFNPSQPP------PGFMPPP----VPPPVVPPP----TIPPVVPT 713 G P P S + S PP G +PPP PPPV PP +PP P Sbjct: 326 SGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPV 385 Query: 714 S 714 S Sbjct: 386 S 386 Score = 33.5 bits (75), Expect = 1.3 Identities = 29/90 (32%), Positives = 35/90 (38%), Gaps = 5/90 (5%) Query: 1028 SRPP--PVDVRDVVGRPIDPREGPGRPPLDGRDHFGRPPVDIRENLVRPGIDHLGRRDHF 1085 SRPP P R +P P GPGR P+ H PP R + P D + D Sbjct: 124 SRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPD-- 181 Query: 1086 GFNPEKPWGHRGDFDEREHR-VLPVYGGPK 1114 P P R +R PV GGP+ Sbjct: 182 SIPPPVPSTPRPIQSSPHNRGSPPVPGGPR 211 >gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo sapiens] Length = 375 Score = 69.7 bits (169), Expect = 2e-11 Identities = 46/114 (40%), Positives = 65/114 (57%), Gaps = 9/114 (7%) Query: 350 SSQQHFLEPEVNLDDSIDIQQQDMDIDEGQDGVEEEVFEQEAKKVAVRSRSRTHSRSRSR 409 SS++H E + + S D ++ ++ E + ++ +K SR R+HSRSRSR Sbjct: 20 SSKKHKSEEHNDKEHSSDKGRERLNSSENGE-------DRHKRKERKSSRGRSHSRSRSR 72 Query: 410 SPRKR-RSRSRSGSRKR-KHRKRSRSRSRERKRKSSRSYSSERRAREREKERQK 461 R R RSR R SR R + RK+SRSRSRERK+ SRS +RR R R + R + Sbjct: 73 ERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSR 126 Score = 66.6 bits (161), Expect = 1e-10 Identities = 41/78 (52%), Positives = 52/78 (66%), Gaps = 6/78 (7%) Query: 397 RSRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRKRSRSRSRERKRKSSRSYSSERRARERE 456 RSRSR +SRSRS +++SRSRS RKR+ R RSRSRSR R R SRS R R R Sbjct: 87 RSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRS-----RTRSRS 141 Query: 457 KERQKKGLPPIR-SKTLS 473 ++R+K+ P R S++LS Sbjct: 142 RDRKKRIEKPRRFSRSLS 159 Score = 62.4 bits (150), Expect = 3e-09 Identities = 37/73 (50%), Positives = 46/73 (63%), Gaps = 3/73 (4%) Query: 389 QEAKKVAVRSRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRKRSRSRSRERKRKSSRSYSS 448 +E KK RSR R SRSRSR +K RSRSR R+ + R RSRSR R R R SR+ S Sbjct: 81 RERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRS- 139 Query: 449 ERRAREREKERQK 461 R+R+R+K +K Sbjct: 140 --RSRDRKKRIEK 150 Score = 60.8 bits (146), Expect = 8e-09 Identities = 40/86 (46%), Positives = 47/86 (54%), Gaps = 2/86 (2%) Query: 389 QEAKKVAVRSRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRKRSRSRSRERKRKSSRSYSS 448 +E KK RSR R SRSRSR RKRR RSRS SR R HR R+RSRSR R R R Sbjct: 91 RERKKSRSRSRERKKSRSRSRE-RKRRIRSRSRSRSR-HRHRTRSRSRTRSRSRDRKKRI 148 Query: 449 ERRAREREKERQKKGLPPIRSKTLSV 474 E+ R + PP R + ++ Sbjct: 149 EKPRRFSRSLSRTPSPPPFRGRNTAM 174 Score = 42.4 bits (98), Expect = 0.003 Identities = 36/89 (40%), Positives = 44/89 (49%), Gaps = 15/89 (16%) Query: 389 QEAKKVAVRSRSR-----THSRSRSRSPRKRRSRSRSGSRKRKHRKR-------SRSRSR 436 +E KK RSR R + SRSRSR + RSRSR+ SR R +KR SRS SR Sbjct: 101 RERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSR 160 Query: 437 ERKRKSSRSYSSERRARE---REKERQKK 462 R ++ A+E R ER KK Sbjct: 161 TPSPPPFRGRNTAMDAQEALARRLERAKK 189 Score = 32.7 bits (73), Expect = 2.3 Identities = 35/138 (25%), Positives = 63/138 (45%), Gaps = 18/138 (13%) Query: 175 PDPWVSQITNTDTLAAVAQILQSPQGQQLQQLIQTLQIQQQKPQPSILQALDAGLVVQLQ 234 P P+ + T D A+A+ L+ + ++LQ+ + +++QK Q A G V+ + Sbjct: 164 PPPFRGRNTAMDAQEALARRLE--RAKKLQEQREKEMVEKQKQQEIAAAAATGGSVLNVA 221 Query: 235 ALTA---QLTAAAAAANTLTPL------EQGVS----FNKKLMDRFDFGEDSEHSE---E 278 AL A Q+T A A + L E G++ +N ++ F E + + + Sbjct: 222 ALLASGTQVTPQIAMAAQMAALQAKALAETGIAVPSYYNPAAVNPMKFAEQEKKRKMLWQ 281 Query: 279 PKKEIPASQLSHVSESVN 296 KKE SQ + + E +N Sbjct: 282 GKKEGDKSQSAEIWEKLN 299 Score = 31.6 bits (70), Expect = 5.0 Identities = 22/73 (30%), Positives = 36/73 (49%), Gaps = 10/73 (13%) Query: 393 KVAVRSRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRKRSRSRSRERKRKS----SRSYSS 448 K + + +S H+ S + R + S + + +H+++ R SR SRS S Sbjct: 19 KSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSR------GRSHSRSRSR 72 Query: 449 ERRAREREKERQK 461 ERR R R +ER+K Sbjct: 73 ERRHRSRSRERKK 85 >gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo sapiens] Length = 434 Score = 69.7 bits (169), Expect = 2e-11 Identities = 46/114 (40%), Positives = 65/114 (57%), Gaps = 9/114 (7%) Query: 350 SSQQHFLEPEVNLDDSIDIQQQDMDIDEGQDGVEEEVFEQEAKKVAVRSRSRTHSRSRSR 409 SS++H E + + S D ++ ++ E + ++ +K SR R+HSRSRSR Sbjct: 79 SSKKHKSEEHNDKEHSSDKGRERLNSSENGE-------DRHKRKERKSSRGRSHSRSRSR 131 Query: 410 SPRKR-RSRSRSGSRKR-KHRKRSRSRSRERKRKSSRSYSSERRAREREKERQK 461 R R RSR R SR R + RK+SRSRSRERK+ SRS +RR R R + R + Sbjct: 132 ERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSR 185 Score = 66.6 bits (161), Expect = 1e-10 Identities = 41/78 (52%), Positives = 52/78 (66%), Gaps = 6/78 (7%) Query: 397 RSRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRKRSRSRSRERKRKSSRSYSSERRARERE 456 RSRSR +SRSRS +++SRSRS RKR+ R RSRSRSR R R SRS R R R Sbjct: 146 RSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRS-----RTRSRS 200 Query: 457 KERQKKGLPPIR-SKTLS 473 ++R+K+ P R S++LS Sbjct: 201 RDRKKRIEKPRRFSRSLS 218 Score = 62.4 bits (150), Expect = 3e-09 Identities = 37/73 (50%), Positives = 46/73 (63%), Gaps = 3/73 (4%) Query: 389 QEAKKVAVRSRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRKRSRSRSRERKRKSSRSYSS 448 +E KK RSR R SRSRSR +K RSRSR R+ + R RSRSR R R R SR+ S Sbjct: 140 RERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRS- 198 Query: 449 ERRAREREKERQK 461 R+R+R+K +K Sbjct: 199 --RSRDRKKRIEK 209 Score = 60.8 bits (146), Expect = 8e-09 Identities = 40/86 (46%), Positives = 47/86 (54%), Gaps = 2/86 (2%) Query: 389 QEAKKVAVRSRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRKRSRSRSRERKRKSSRSYSS 448 +E KK RSR R SRSRSR RKRR RSRS SR R HR R+RSRSR R R R Sbjct: 150 RERKKSRSRSRERKKSRSRSRE-RKRRIRSRSRSRSR-HRHRTRSRSRTRSRSRDRKKRI 207 Query: 449 ERRAREREKERQKKGLPPIRSKTLSV 474 E+ R + PP R + ++ Sbjct: 208 EKPRRFSRSLSRTPSPPPFRGRNTAM 233 Score = 47.4 bits (111), Expect = 9e-05 Identities = 28/73 (38%), Positives = 41/73 (56%), Gaps = 5/73 (6%) Query: 388 EQEAKKVAVRSRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRKRSRSRSRERKRKSSRSYS 447 EQ V+ R+ +SRSRSRS ++R G RKH RSRSRS+E +R S+ S Sbjct: 25 EQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEG---RKH--RSRSRSKEGRRHESKDKS 79 Query: 448 SERRAREREKERQ 460 S++ E +++ Sbjct: 80 SKKHKSEEHNDKE 92 Score = 43.1 bits (100), Expect = 0.002 Identities = 38/136 (27%), Positives = 58/136 (42%), Gaps = 38/136 (27%) Query: 364 DSIDIQQQDMDIDEGQDGVEEEVFEQEAKKVAVRSRSRTHSRSRSRSPRKRRSRSRSGSR 423 D + ++ D D+ ++ E V + +K RSRSR+ R R R+ RSRS S+ Sbjct: 9 DGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSK 68 Query: 424 K-RKHRKRSRS-------------------------------RSRERKRKS------SRS 445 + R+H + +S R + ++RKS SRS Sbjct: 69 EGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRS 128 Query: 446 YSSERRAREREKERQK 461 S ERR R R +ER+K Sbjct: 129 RSRERRHRSRSRERKK 144 Score = 42.4 bits (98), Expect = 0.003 Identities = 36/89 (40%), Positives = 44/89 (49%), Gaps = 15/89 (16%) Query: 389 QEAKKVAVRSRSR-----THSRSRSRSPRKRRSRSRSGSRKRKHRKR-------SRSRSR 436 +E KK RSR R + SRSRSR + RSRSR+ SR R +KR SRS SR Sbjct: 160 RERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSR 219 Query: 437 ERKRKSSRSYSSERRARE---REKERQKK 462 R ++ A+E R ER KK Sbjct: 220 TPSPPPFRGRNTAMDAQEALARRLERAKK 248 Score = 40.8 bits (94), Expect = 0.008 Identities = 29/66 (43%), Positives = 33/66 (50%), Gaps = 9/66 (13%) Query: 406 SRSRSPRKRRSRSRSGSRKRKHR-KRSRSRSRERKRKS--------SRSYSSERRARERE 456 S R +K +S R KH RSRSRSRERKRKS SRS S E R E + Sbjct: 17 SPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESK 76 Query: 457 KERQKK 462 + KK Sbjct: 77 DKSSKK 82 Score = 32.7 bits (73), Expect = 2.3 Identities = 35/138 (25%), Positives = 63/138 (45%), Gaps = 18/138 (13%) Query: 175 PDPWVSQITNTDTLAAVAQILQSPQGQQLQQLIQTLQIQQQKPQPSILQALDAGLVVQLQ 234 P P+ + T D A+A+ L+ + ++LQ+ + +++QK Q A G V+ + Sbjct: 223 PPPFRGRNTAMDAQEALARRLE--RAKKLQEQREKEMVEKQKQQEIAAAAATGGSVLNVA 280 Query: 235 ALTA---QLTAAAAAANTLTPL------EQGVS----FNKKLMDRFDFGEDSEHSE---E 278 AL A Q+T A A + L E G++ +N ++ F E + + + Sbjct: 281 ALLASGTQVTPQIAMAAQMAALQAKALAETGIAVPSYYNPAAVNPMKFAEQEKKRKMLWQ 340 Query: 279 PKKEIPASQLSHVSESVN 296 KKE SQ + + E +N Sbjct: 341 GKKEGDKSQSAEIWEKLN 358 >gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] Length = 494 Score = 69.3 bits (168), Expect = 2e-11 Identities = 39/63 (61%), Positives = 43/63 (68%), Gaps = 1/63 (1%) Query: 398 SRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRK-RSRSRSRERKRKSSRSYSSERRARERE 456 SRSR+HSRSRSRS R+SRSRSGS K H K RSRSRS R R SRS S R ++E Sbjct: 186 SRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKE 245 Query: 457 KER 459 K R Sbjct: 246 KSR 248 Score = 54.7 bits (130), Expect = 6e-07 Identities = 32/74 (43%), Positives = 45/74 (60%), Gaps = 1/74 (1%) Query: 397 RSRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRKRSRSRSRERKRKSSRSYS-SERRARER 455 +SRSR+ S SRSRS + RS+SRS S+K K R S+ +SR R + +S S S+ +A E+ Sbjct: 217 KSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEK 276 Query: 456 EKERQKKGLPPIRS 469 + G P RS Sbjct: 277 IQNNDNVGKPKSRS 290 Score = 52.8 bits (125), Expect = 2e-06 Identities = 49/193 (25%), Positives = 77/193 (39%), Gaps = 31/193 (16%) Query: 274 EHSEEPKKEIPASQLSHVSESVNNSIFHQIAEQLQQQ-NLEHLRQQLLEQQQPQKATPQD 332 E S P KE S+ SH + + Q E++Q N+ + + + + + + Sbjct: 245 EKSRSPSKEKSRSR-SHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSR 303 Query: 333 SQEGTFGSEHSASPSQGSSQQHFLEPEVNLDDSIDIQQQDMDIDEGQDGVEEEVFEQEAK 392 SQE E S S+G SQ+ L +Q + G Sbjct: 304 SQERRVEEEKRGSVSRGRSQEKSL-------------RQSRSRSRSKGG----------- 339 Query: 393 KVAVRSRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRKRSRSRSRERKRKSSRSYSSERRA 452 SRSR+ SRS+S+ RK R RSR SR R + RSR+R K S ++ Sbjct: 340 -----SRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKK 394 Query: 453 REREKERQKKGLP 465 ++ + +R + P Sbjct: 395 KKEDTDRSQSRSP 407 Score = 52.4 bits (124), Expect = 3e-06 Identities = 40/75 (53%), Positives = 45/75 (60%), Gaps = 11/75 (14%) Query: 397 RSRSRTHSRSRSR------SPRKRRSRSRSGSRKR-KHRKRSRSRSRERKRKSSRSYSSE 449 RSRSR +SRSR S K RSRSRSGSR R K R RS+SRSR +K K SRS S E Sbjct: 195 RSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEK-SRSPSKE 253 Query: 450 R---RAREREKERQK 461 + R+ K R K Sbjct: 254 KSRSRSHSAGKSRSK 268 Score = 51.2 bits (121), Expect = 6e-06 Identities = 38/141 (26%), Positives = 68/141 (48%), Gaps = 10/141 (7%) Query: 308 QQQNLEHLRQQLLEQQQPQKATPQDSQEGTFGSEHSASPSQGSSQQHFLEPEVNLDDSID 367 ++++ R + ++ ++ + +DS+ G+ + + S+ P ++ + Sbjct: 361 REESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRS----PSRSVSKERE 416 Query: 368 IQQQDMDIDEGQDGVEEEVFEQEAKKVAVRSRSRTHSRSRSRSPRKRRSRSRSGSRKRKH 427 + + EG+ E QE RSRSR++S+S+ P + RSRS+S S+ R Sbjct: 417 HAKSESSQREGRGESENAGTNQET-----RSRSRSNSKSKPNLPSESRSRSKSASKTRSR 471 Query: 428 RK-RSRSRSRERKRKSSRSYS 447 K RSRS SR R SRS+S Sbjct: 472 SKSRSRSASRSPSRSRSRSHS 492 Score = 45.1 bits (105), Expect = 4e-04 Identities = 31/95 (32%), Positives = 43/95 (45%), Gaps = 12/95 (12%) Query: 391 AKKVAVRSRSRTHSRSRSRSPRKRRSRSRS------------GSRKRKHRKRSRSRSRER 438 +KK RS S+ SRSRS S K RS+S+ G K + R +S+S+ R Sbjct: 242 SKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSR 301 Query: 439 KRKSSRSYSSERRAREREKERQKKGLPPIRSKTLS 473 R R E+R Q+K L RS++ S Sbjct: 302 SRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRS 336 Score = 41.2 bits (95), Expect = 0.006 Identities = 29/78 (37%), Positives = 41/78 (52%), Gaps = 16/78 (20%) Query: 412 RKRRSRSRSGSRKR-----KHRKRSRSR----------SRERKRKSSRSYSSER-RARER 455 R+RRS SRS S R +H ++SRSR SR R R SRS S R R++ R Sbjct: 180 RRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSR 239 Query: 456 EKERQKKGLPPIRSKTLS 473 + +++K P + K+ S Sbjct: 240 SRSKKEKSRSPSKEKSRS 257 Score = 38.9 bits (89), Expect = 0.032 Identities = 29/99 (29%), Positives = 46/99 (46%), Gaps = 8/99 (8%) Query: 369 QQQDMDIDEGQDGVEEEVFEQEAKKVAVRSRSRTHSRSRSRSPRKRRSRSRSGSRKR--- 425 +++D D + + E+E K R + + ++ RSRSRS S+ + Sbjct: 395 KKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNL 454 Query: 426 --KHRKRSRSRSRERKRKSSRSYSSER---RAREREKER 459 + R RS+S S+ R R SRS S+ R R+R R R Sbjct: 455 PSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSR 493 Score = 35.4 bits (80), Expect = 0.35 Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 3/82 (3%) Query: 341 EHSASPSQGSSQQHFLEPEVNLDDSIDIQQQDMDIDEGQDGVEEEVFEQEAKKVAVRSRS 400 EH+ S S SQ+ N + + + + + + + E + RSRS Sbjct: 416 EHAKSES---SQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRS 472 Query: 401 RTHSRSRSRSPRKRRSRSRSGS 422 ++ SRS SRSP + RSRS S S Sbjct: 473 KSRSRSASRSPSRSRSRSHSRS 494 Score = 32.7 bits (73), Expect = 2.3 Identities = 20/55 (36%), Positives = 29/55 (52%), Gaps = 5/55 (9%) Query: 414 RRSRSRSGSRKRKH--RKRSRSRSRERKRKSSRSYS---SERRAREREKERQKKG 463 R + GSR+R+ R RS SRSR R R S +S S S + + + + R + G Sbjct: 171 RLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSG 225 >gi|14670268 RD RNA-binding protein [Homo sapiens] Length = 380 Score = 68.9 bits (167), Expect = 3e-11 Identities = 73/269 (27%), Positives = 111/269 (41%), Gaps = 25/269 (9%) Query: 276 SEEPKKEIPASQLSHVSESVNNSIFHQIAEQLQQQNLEHLRQQLLEQQQPQKATPQDSQE 335 +E+ K+ + + +S + NS F + L +L + ++ T Q Q Sbjct: 62 TEQAKQLVKSGAISAIKAETKNSGF---------KRSRTLEGKLKDPEKGPVPTFQPFQR 112 Query: 336 GTFGSEHSASPSQGSSQQHFLEPEVNLDDSIDIQQQDMDIDEGQ---DGVEEEV-FEQEA 391 + S+ ++ E V+ D + D + EG DG + E Sbjct: 113 SISADDDLQESSRRPQRKSLYESFVSSSDRLRELGPDGEEAEGPGAGDGPPRSFDWGYEE 172 Query: 392 KKVAVRSRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRKRSRSRSRERKRKSSRSYSSER- 450 + A S S SRSR RS + R R R R R R R R R R+R R R ER Sbjct: 173 RSGAHSSASPPRSRSRDRSHERNRDRDRDRERDRD-RDRDRDRERDRDRDRDRDRDRERD 231 Query: 451 RAREREKERQKKGLPPIR------SKTLSVCSTTLWVGQVDKKATQQDLTNLFEEFGQIE 504 R RER+++R ++G P R + TL+V D T L F FG I Sbjct: 232 RDRERDRDRDREG--PFRRSDSFPERRAPRKGNTLYVYGEDMTPTL--LRGAFSPFGNII 287 Query: 505 SINMIPPRGCAYVCMVHRQDAFRALQKLS 533 ++M PPR CA+V + A +A+ +L+ Sbjct: 288 DLSMDPPRNCAFVTYEKMESADQAVAELN 316 >gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens] Length = 1711 Score = 68.6 bits (166), Expect = 4e-11 Identities = 87/381 (22%), Positives = 139/381 (36%), Gaps = 61/381 (16%) Query: 618 PTPVEKETVVTTQAEVFPPPVAMLQIPVAPAVPTVSLVPPAFPVSMPVPPPGFSPIPPPP 677 P P+ V PP+A++Q PV P+ PT+ L PVP P +P+P Sbjct: 294 PVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLA--------PVPTPVLAPMP--- 342 Query: 678 FLRASFNPSQPPPGFMPPPVPPPVVPPPTIPPVVPTSLVQPSLSMTPETVKDVGFGSLVI 737 AS P+ P P +P P P P PP+ P ++P P + TP + + Sbjct: 343 ---ASTPPAAPAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTP--APTPM 397 Query: 738 PGGSVASNLATSALPAGNVFNA---PTKQAEPEEKVPHLIDHQISSGENTRSVIPNDISS 794 P + A+ ++ +PA + P QA +KVP Sbjct: 398 PAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVP----------------------- 434 Query: 795 NAAILGGQPPNVTSNSGILGVQRPNVSSNSEILGVRPSNVSSSSGIIAAQPPNILNNSGI 854 L QP V + S L P + P+ + SS + P+ L + + Sbjct: 435 ----LSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCL 490 Query: 855 LGI-QPPSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGLLGTQPPAGPQNLP-PLS 912 G+ P + + V P + ++S LV ++ +P T T P +P PL+ Sbjct: 491 PGVLASPELRSYPYAFSVARP-LTSDSKLVSLEVNRLPCTSPSGSTTTQPAPDGVPGPLA 549 Query: 913 IPNQRMPTMPMLDIRPGLIPQAPG---PRFPLIQPGIPPQR---------GIPPPSVLDS 960 + + +L L+P G P P P Q+ + P L+ Sbjct: 550 DTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSPLKSPPQLER 609 Query: 961 ALHPPPRGPFPPGDIFSQPER 981 + PP P D+ S+ R Sbjct: 610 EMASPPECSEMPLDLSSKSNR 630 Score = 39.3 bits (90), Expect = 0.024 Identities = 45/159 (28%), Positives = 63/159 (39%), Gaps = 16/159 (10%) Query: 614 TTQSPTPVEKET-VVTTQAEVFPPPVAMLQIPVAPAVPTVS-LVPPAFPVSMPVPPPGFS 671 T + PVE +VTT P P+ P AP +V VP AF V + VP + Sbjct: 178 TLGTGVPVEGTLPLVTTNFSPLPAPIC----PPAPGSASVPHSVPDAFQVPLSVP----A 229 Query: 672 PIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPPPTIPPVV----PTSLVQPSLSMTPETV 727 P+P + S P P PVP PP++P ++ P S+ L P + Sbjct: 230 PVPHSGLVPVQVATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASA 289 Query: 728 KDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEP 766 G L P + S + SA P + AP + P Sbjct: 290 PPSGPVPLSAPAPAPLS-VPVSAPPLA-LIQAPVPPSAP 326 Score = 34.3 bits (77), Expect = 0.78 Identities = 36/131 (27%), Positives = 57/131 (43%), Gaps = 17/131 (12%) Query: 383 EEEVFEQEAKKVAVRSRSRTHSRSRSRSPRKRRSRS-RSGSRKRKHRKRSRSRSRERKRK 441 EE+ + +AK V VRS R R P++ +S R S K R + + RK Sbjct: 1128 EEQQLQPQAKAV-VRSSHRPKCRKLPSDPQESTKKSPRGASDSGKEHNGVRGKHKHRKPT 1186 Query: 442 SSRSYSSERRAREREK---ERQKKG-----LPPI-----RSKTLSVCSTTLWVGQVDKKA 488 S S +RA E+ E++ K +P + RS++ S+CS+ + G D Sbjct: 1187 KPESQSPGKRADSHEEGSLEKKAKSSFRDFIPVVLSTRTRSQSGSICSS--FAGMADSDM 1244 Query: 489 TQQDLTNLFEE 499 Q++ EE Sbjct: 1245 GSQEVFPTEEE 1255 Score = 32.3 bits (72), Expect = 3.0 Identities = 30/129 (23%), Positives = 56/129 (43%), Gaps = 16/129 (12%) Query: 327 KATPQDSQEGTFGSEHSASPSQGSSQQHFLEPEVNLDDSIDIQQQDMDIDEGQDGVEEEV 386 + T +D+Q + S H+ S S + L + + +Q D +E ++ EEE Sbjct: 1269 RKTQRDTQ---YRSHHAQDKSLLSQGRRHLWRAREMPWRTEAARQMWDTNEEEEEEEEEG 1325 Query: 387 FEQEAKKVAVRSRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRKRSRSRSRERKRKSSRSY 446 + K+ R + RK ++ ++ + R++ R+ + RK+K+S S Sbjct: 1326 LLKRKKR-------------RRQKSRKYQTGEYLTEQEDEQRRKGRADLKARKQKTSSSQ 1372 Query: 447 SSERRARER 455 S E R R R Sbjct: 1373 SLEHRLRNR 1381 Score = 31.6 bits (70), Expect = 5.0 Identities = 49/173 (28%), Positives = 66/173 (38%), Gaps = 23/173 (13%) Query: 828 GVRPSNVSSSSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQP 887 G+ P V++S + A PP L L PPSV L+ P + S LV V Sbjct: 235 GLVPVQVATS--VPAPSPP--LAPVPALAPAPPSVPT---LISDSNPLSVSASVLVPVPA 287 Query: 888 PNVPNTPGLLGTQPPAG---PQNLPPLSIPNQRMP-TMPMLDIRP------GLIPQAPGP 937 P+ P L PA P + PPL++ +P + P L + P +P + P Sbjct: 288 SAPPSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPP 347 Query: 938 RFPLIQPGIP-----PQRGIPPPSVLDSALHPPPRGPFPPGDIFSQPERPFLA 985 P P +P P G P L A P P P IF+ P A Sbjct: 348 AAPA-PPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPA 399 Score = 31.6 bits (70), Expect = 5.0 Identities = 25/117 (21%), Positives = 49/117 (41%), Gaps = 22/117 (18%) Query: 383 EEEVFEQEAKKVAVRSRSRT------HSRSRSRSPRKRRSRSRS---------------- 420 EEEV AK+ VR R H++ +S + RR R+ Sbjct: 1255 EEEVTPTPAKRRKVRKTQRDTQYRSHHAQDKSLLSQGRRHLWRAREMPWRTEAARQMWDT 1314 Query: 421 GSRKRKHRKRSRSRSRERKRKSSRSYSSERRAREREKERQKKGLPPIRSKTLSVCST 477 + + + + ++R+R+ SR Y + E+E E+++KG ++++ S+ Sbjct: 1315 NEEEEEEEEEGLLKRKKRRRQKSRKYQTGEYLTEQEDEQRRKGRADLKARKQKTSSS 1371 >gi|24307919 small nuclear ribonucleoprotein 27kDa (U4/U6.U5) [Homo sapiens] Length = 155 Score = 67.4 bits (163), Expect = 8e-11 Identities = 44/108 (40%), Positives = 62/108 (57%), Gaps = 6/108 (5%) Query: 405 RSRSRSPRKRRSRSRSGSRKRKHRKRSRSRSRERKRKSSRSYSSERRAREREKERQKKGL 464 RSRSRSPR+ R RSRS SR+R+ R+R RSRSRER R+ SRS S RR R R R + Sbjct: 3 RSRSRSPRRERRRSRSTSRERERRRRERSRSRERDRRRSRSRSPHRR-RSRSPRRHRSTS 61 Query: 465 PP---IRSKTLSVCSTTLWVGQVDKKATQQDLTNLFEEFGQIESINMI 509 P ++ + T +++ T++DL EE +IE + ++ Sbjct: 62 PSPSRLKERRDEEKKETKETKSKERQITEEDLEGKTEE--EIEMMKLM 107 Score = 49.3 bits (116), Expect = 2e-05 Identities = 31/72 (43%), Positives = 40/72 (55%), Gaps = 6/72 (8%) Query: 397 RSRSRTHSRSRSRSPRKR-RSRSRSGSRKRK-----HRKRSRSRSRERKRKSSRSYSSER 450 R R R+ S SR R R+R RSRSR R+R HR+RSRS R R S S ER Sbjct: 11 RERRRSRSTSRERERRRRERSRSRERDRRRSRSRSPHRRRSRSPRRHRSTSPSPSRLKER 70 Query: 451 RAREREKERQKK 462 R E+++ ++ K Sbjct: 71 RDEEKKETKETK 82 Score = 47.0 bits (110), Expect = 1e-04 Identities = 30/68 (44%), Positives = 38/68 (55%), Gaps = 11/68 (16%) Query: 397 RSRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRKRSRSRSR------ERKRKSSRSYSSER 450 RSR R RSRSRSP +RRSRS R+HR S S SR E K+++ + S ER Sbjct: 32 RSRERDRRRSRSRSPHRRRSRS-----PRRHRSTSPSPSRLKERRDEEKKETKETKSKER 86 Query: 451 RAREREKE 458 + E + E Sbjct: 87 QITEEDLE 94 Score = 45.1 bits (105), Expect = 4e-04 Identities = 24/66 (36%), Positives = 35/66 (53%) Query: 397 RSRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRKRSRSRSRERKRKSSRSYSSERRARERE 456 RSRSR+ R RSRSPR+ RS S S SR ++ R + ++E K K + + + E Sbjct: 40 RSRSRSPHRRRSRSPRRHRSTSPSPSRLKERRDEEKKETKETKSKERQITEEDLEGKTEE 99 Query: 457 KERQKK 462 + K Sbjct: 100 EIEMMK 105 >gi|146134388 YLP motif containing 1 [Homo sapiens] Length = 2146 Score = 67.4 bits (163), Expect = 8e-11 Identities = 69/245 (28%), Positives = 99/245 (40%), Gaps = 35/245 (14%) Query: 635 PPPVAMLQIPVAPAVPTVSLVPPAFPVSMPVP-------PPGFSPIPPPPFLRASFNPSQ 687 PPP+ + PV P ++PPA P ++P P PP PPP + S + + Sbjct: 527 PPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAG 586 Query: 688 PPPGFMPPPV----PPPVVPPPTI-----PPVVPTSLVQPSLSMTPETVKDVGFGSLVIP 738 PPP PP + PPPV+PPP++ PPV+P + P S TP G +P Sbjct: 587 PPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMP---LPPLSSATPPP----GIPPPGVP 639 Query: 739 GGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDHQISSGENTRSVIPNDISSNAAI 798 G A PA ++ PE+ P L+ +S G + + S Sbjct: 640 QGIPPQLTAAPVPPA----SSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPLQS---- 691 Query: 799 LGGQPPNVTSNSGILGVQRPNVSSNSEILGVRPSNVSSSSGIIAAQPPNILNNSGILGIQ 858 G V S + + P SS S G+ S+ + S I A + + SG L Sbjct: 692 -AGPSEQVNSKAPLSKSALP-YSSFSSDQGLGESSAAPSQPITAVKDMPV--RSGGLLPD 747 Query: 859 PPSVS 863 PP S Sbjct: 748 PPRSS 752 Score = 63.9 bits (154), Expect = 9e-10 Identities = 62/208 (29%), Positives = 81/208 (38%), Gaps = 44/208 (21%) Query: 600 ETVKSSEPVKETVQTTQS-PTPVEKETVVTTQAEVFPPPVA--MLQIPVAP-----AVPT 651 E V S + +K S P P + + PPPV L PV P VP Sbjct: 498 EKVNSFQNMKNQYMGNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPP 557 Query: 652 VSLVPPAFPVSMP--VPPPGFSP----------IPPPPFLRASFNPSQPPPGFM---PPP 696 + PP P S+P VPPPG P +PPP A P PPP PPP Sbjct: 558 PGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPP 617 Query: 697 V----------PPPVVPPPTIPPVVPTSL----VQPSLSMTPETVKDVGFGSLVIPGGSV 742 V PPP +PPP +P +P L V P+ S V + +L+ S Sbjct: 618 VMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSF 677 Query: 743 ASNLATSALPAGNVFNAPTKQAEPEEKV 770 S T+ ++ P + A P E+V Sbjct: 678 GSAPPTT-------YHPPLQSAGPSEQV 698 Score = 60.8 bits (146), Expect = 8e-09 Identities = 79/324 (24%), Positives = 124/324 (38%), Gaps = 27/324 (8%) Query: 647 PAVPTVSLVPPAFPVSMPVPPPGFSPIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPPPT 706 P VP + PP + PV PP P PP L A+ P PP MPP +P VPPP Sbjct: 519 PFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTS-VPPPG 577 Query: 707 IPPVVPTSLVQPSLSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEP 766 +PP + S P + P ++ G V+P S++S +P + +A P Sbjct: 578 MPPSL--SSAGPPPVLPPPSLSSAG-PPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIP 634 Query: 767 EEKVPHLIDHQISSGENTRSVIPNDISSNAAILGGQPPNVTSNSGILGVQRPNVSSNSEI 826 VP I Q+ T + +P SS ++ + +P + + P + + + Sbjct: 635 PPGVPQGIPPQL-----TAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPL 689 Query: 827 LGVRPSNVSSSSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQ 886 PS +S ++ + S G+ S + S + V ++P SG + Sbjct: 690 QSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPITAV--KDMPVRSGGL--- 744 Query: 887 PPNVPNTPGLLGTQPPAGPQNLPPLSIPNQRMPTMPMLDIRPGLIPQAPGPRFPLIQPGI 946 +P+ P + P GP+ P + P+ GPRF +P Sbjct: 745 ---LPDPPRSSYLESPRGPRFDGPRRFEDLGSRCEG---------PRPKGPRFEGNRPDG 792 Query: 947 P-PQRGIPPPSVLDSALHPPPRGP 969 P P+ P S PRGP Sbjct: 793 PRPRYEGHPAEGTKSKWGMIPRGP 816 Score = 46.2 bits (108), Expect = 2e-04 Identities = 47/143 (32%), Positives = 57/143 (39%), Gaps = 21/143 (14%) Query: 855 LGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGLLGTQPPAG---------- 904 L PP V S V+PP +P G+ PP +P P L + PP G Sbjct: 530 LPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMP--PSLPTSVPPPGMPPSLSSAGP 587 Query: 905 PQNLPPLSIPNQRMPTMPMLDIRPGLIPQAPGPRFPL--IQPGIPPQRGIPPPSVLDSAL 962 P LPP S+ + P P+L P L AP P PL + PP GIPPP V Sbjct: 588 PPVLPPPSLSSAGPP--PVLP-PPSLSSTAPPPVMPLPPLSSATPPP-GIPPPGVPQGIP 643 Query: 963 HPPPRGPFPPGDIFSQ---PERP 982 P PP PE+P Sbjct: 644 PQLTAAPVPPASSSQSSQVPEKP 666 Score = 43.9 bits (102), Expect = 0.001 Identities = 31/89 (34%), Positives = 37/89 (41%), Gaps = 32/89 (35%) Query: 665 VPPPGFSPIPPPPFLRAS-FNPSQPPPGFMPPPV-----------------------PPP 700 +PPP P+PPPP + + QPPP MPPP PP Sbjct: 81 LPPP---PLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPG 137 Query: 701 VVP-----PPTIPPVVPTSLVQPSLSMTP 724 +VP PP PPV P S + PS S P Sbjct: 138 LVPMELESPPESPPVPPGSYMPPSQSYMP 166 Score = 42.7 bits (99), Expect = 0.002 Identities = 22/57 (38%), Positives = 28/57 (49%), Gaps = 3/57 (5%) Query: 654 LVPPAFPVSMPVP---PPGFSPIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPPPTI 707 + PP P P PPG P P R+S ++PP PPP PPP+ PPP + Sbjct: 1505 MYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLPPPPPV 1561 Score = 42.0 bits (97), Expect = 0.004 Identities = 39/122 (31%), Positives = 52/122 (42%), Gaps = 23/122 (18%) Query: 887 PPNVPNTPGLLGT-----QPPAGPQNLPP---LSIPNQRMPTMPML----DIRPGLIP-- 932 PP +P P + G QPP P PP LS Q+ ML D PGL+P Sbjct: 83 PPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVPME 142 Query: 933 -QAPGPRFPLIQPG--IPPQRGIPPPSVLDSALHPPPRG-----PFPPGDIFSQPERPFL 984 ++P P P + PG +PP + PP + +PP P P S P + +L Sbjct: 143 LESP-PESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYL 201 Query: 985 AP 986 AP Sbjct: 202 AP 203 Score = 40.4 bits (93), Expect = 0.011 Identities = 29/90 (32%), Positives = 36/90 (40%), Gaps = 16/90 (17%) Query: 620 PVEKETVVTTQAEVFPPPVAMLQIPVAPAVPTVSLVPPAFPVSMPVPPPGFSPIPPPPFL 679 P E T+ PP + P P S+V P+ P + P P+P PP Sbjct: 1491 PQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPP-- 1548 Query: 680 RASFNPSQPPPGFMPPPVPPPVVPPPTIPP 709 PPP PPP+PP PPP I P Sbjct: 1549 --------PPP---PPPLPP---PPPVIKP 1564 Score = 39.7 bits (91), Expect = 0.019 Identities = 32/114 (28%), Positives = 48/114 (42%), Gaps = 20/114 (17%) Query: 656 PPAFPVSMPVPPPGFSPIPPPPFLRASFN---PSQPPPGFMPPPVPPPVVPPPTIPPVVP 712 P P+ + PP P+PP ++ S + P QPPP + PP P +PP Sbjct: 136 PGLVPMELESPPES-PPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPP-------- 186 Query: 713 TSLVQPSLSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEP 766 QPS S +P + + P S +S+ + S L + P+ QA P Sbjct: 187 ---AQPSPSQSPPSQSYLA----PTPSYSSSSSSSQSYLSHSQSY-LPSSQASP 232 Score = 39.7 bits (91), Expect = 0.019 Identities = 98/388 (25%), Positives = 139/388 (35%), Gaps = 64/388 (16%) Query: 902 PAGPQNLPPLSIPNQRMPTMPMLDIRPGLIPQAPG---PRFPLIQPGIPPQRGIPPPSVL 958 P +LPP Q + P + PG P P +++P PP R P + Sbjct: 1483 PQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRP 1542 Query: 959 DSALHPPPRGPFPPGDIFSQPERPFLAPGRQSVDNVT-NPEKRIPLGNDNIQQEGDRDYR 1017 + PPP P PP P P + P +V+ + + L + N +Q + +++ Sbjct: 1543 PVPIPPPP--PPPP----LPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFK 1596 Query: 1018 -----------FPPIETRESISRPPPVDVRDVVGRPIDPREGPGRPPLDGRDHFGRPPVD 1066 PP SI P PV +G P P P PP+ +G D Sbjct: 1597 SETAAIPSAPVLPPPPVHSSIPPPGPVP----MGMP--PMSKP--PPVQQTVDYGHGR-D 1647 Query: 1067 IRENLVRPGIDHLGRRDHFGFNPEKPWGHRGDFDEREHRVLPVYGGPKGLHEERGRFRSG 1126 I N V + + + P+ P R F E EH G + R R Sbjct: 1648 ISTNKV----EQIPYGERITLRPD-PLPERSTF-ETEH---------AGQRDRYDRERDR 1692 Query: 1127 NYRFDPRSGPWNRGFGQEVHRDFD-DRRRPWERQRDRDDRDFDFCREMNGNRLGRDRIQN 1185 FD +S HRDF DR +R RDR D+D R R DR Q+ Sbjct: 1693 EPYFDRQSNV------IADHRDFKRDRETHRDRDRDRGVIDYDRDRFDRERRPRDDRAQS 1746 Query: 1186 TWVPPPHARV-FDYFEGATSQRKGDNVPQVNGENT---ERHAQPP---PIPVQNDPELYE 1238 H+ F+ + RK D P G + ER P P+P P L Sbjct: 1747 YRDKKDHSSSRRGGFDRPSYDRKSDR-PVYEGPSMFGGERRTYPEERMPLPA---PSLSH 1802 Query: 1239 KLTSSNEINKE-KSDTVADIESEPVVES 1265 + + + K+ +S V DI P ES Sbjct: 1803 QPPPAPRVEKKPESKNVDDILKPPGRES 1830 Score = 39.3 bits (90), Expect = 0.024 Identities = 32/128 (25%), Positives = 46/128 (35%), Gaps = 35/128 (27%) Query: 636 PPVAMLQIPVAPAVPTVSLVPPAFPVSMPVPPPGFSPIPPPP------------------ 677 PP ++++ PA +V + P P+ P PPP P+PPPP Sbjct: 1521 PPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPP---PLPPPPPVIKPQTSAVEQERWDED 1577 Query: 678 ------------FLRASFNPSQPPPGFMPPPVPPPVVPPPTIPPVVPTSLVQPSLSMTPE 725 L + F P PPPV +IPP P + P +S P Sbjct: 1578 SFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPV--HSSIPPPGPVPMGMPPMSKPPP 1635 Query: 726 TVKDVGFG 733 + V +G Sbjct: 1636 VQQTVDYG 1643 Score = 38.9 bits (89), Expect = 0.032 Identities = 31/100 (31%), Positives = 41/100 (41%), Gaps = 21/100 (21%) Query: 904 GPQNLPPLSIPNQRMP----TMPMLDIRPGLIPQAPGPRFPLIQPGIPPQRGIPPPSV-- 957 G ++PP +P +MP TMP P L P P P P P P G+PPP + Sbjct: 512 GNMSMPPPFVPYSQMPPPLPTMPP----PVLPPSLPPPVMPPALPATVPPPGMPPPVMPP 567 Query: 958 -LDSALHPPPRGP----------FPPGDIFSQPERPFLAP 986 L +++ PP P PP + S P L P Sbjct: 568 SLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPP 607 Score = 38.1 bits (87), Expect = 0.054 Identities = 36/151 (23%), Positives = 57/151 (37%), Gaps = 18/151 (11%) Query: 637 PVAMLQIPVAPAVPTVSLVPPAFPVSMPVPPPGFSPIPPPPFLRASFNPSQPPPGFMPPP 696 P+ + P +P VP S +PP S PP P PPP S+ P ++PP Sbjct: 140 PMELESPPESPPVPPGSYMPP----SQSYMPP---PQPPP-----SYYPPTSSQPYLPPA 187 Query: 697 VPPPVVPPPTIPPVVPTSLVQPSLSMTPETVKD-VGFGSLVIPGGSVASNLATSALPAGN 755 P P PP+ + PT PS S + + + + +P + + + Sbjct: 188 QPSPSQSPPSQSYLAPT----PSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQ 243 Query: 756 VFNAPTKQAEPEEKVPHLIDHQISSGENTRS 786 + P A P K + + SG +S Sbjct: 244 LLAPPPPSAPPGNKTT-VQQEPLESGAKNKS 273 Score = 36.6 bits (83), Expect = 0.16 Identities = 25/64 (39%), Positives = 32/64 (50%), Gaps = 11/64 (17%) Query: 666 PPPGFSPIPPPPF-------LRASFNPSQPPPGFMPPPVPPP-VVPPPTIPPVVPTSLVQ 717 PPPG S PPPP +R S P++ PPVP P PPP +PP P +++ Sbjct: 1507 PPPG-SYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLPP--PPPVIK 1563 Query: 718 PSLS 721 P S Sbjct: 1564 PQTS 1567 Score = 35.0 bits (79), Expect = 0.46 Identities = 26/95 (27%), Positives = 42/95 (44%), Gaps = 13/95 (13%) Query: 128 IQPLLDMAAGIPPPVVTPVLASTTTAMSNTPGTPVTPVTPANVVQGLPDPWVSQITNTDT 187 + P +++ PPPV+ P S+T + P P+ P++ A G+P P V Q Sbjct: 590 VLPPPSLSSAGPPPVLPPPSLSST---APPPVMPLPPLSSATPPPGIPPPGVPQGIPPQL 646 Query: 188 LAAVAQILQSPQGQQLQQLIQTLQIQQQKPQPSIL 222 AA S Q Q+ +KP+P++L Sbjct: 647 TAAPVPPASSSQSSQV----------PEKPRPALL 671 Score = 32.3 bits (72), Expect = 3.0 Identities = 31/108 (28%), Positives = 44/108 (40%), Gaps = 12/108 (11%) Query: 600 ETVKSSEPVKETVQTTQSP-------TPVEKETVVTTQAEVFPPPVAMLQIPVAPAVPTV 652 E ++S K T Q +P TP E++ Q + + +P P V Sbjct: 263 EPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVV 322 Query: 653 SLVPPAFPVSMPVPPPGFSPIPPPPFLRASFNPSQPPPG-FMPPPVPP 699 + P PV V P S +P P +S P PPP +PPP+PP Sbjct: 323 AKDTPE-PVKEEVTVPATSQVPESP---SSEEPPLPPPNEEVPPPLPP 366 Score = 31.6 bits (70), Expect = 5.0 Identities = 78/370 (21%), Positives = 118/370 (31%), Gaps = 78/370 (21%) Query: 655 VPPAFPVSMPV--PPPGFS----PIPPPPFLRASFNPSQ-------------------PP 689 VPP PV++P P PG+S P P SF P Sbjct: 19 VPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQCVLQP 78 Query: 690 PGFMPPPVPPPVV------------PPPTIPPVVPTSLVQPSLSMTPETVKDVGFGSLVI 737 PPP+PPP V PPP PP P Q + + G + Sbjct: 79 HHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGL 138 Query: 738 PGGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDHQISSGENTRSVIPNDISSNAA 797 + S + +P G+ + P++ P + P S P SS Sbjct: 139 VPMELESPPESPPVPPGS-YMPPSQSYMPPPQPP-------------PSYYP-PTSSQPY 183 Query: 798 ILGGQP-PNVTSNSGILGVQRPNVSSNSEILGVRPSNVSSSSGIIAAQPPNILNNSGILG 856 + QP P+ + S P+ SS+ SSSS + + L +S Sbjct: 184 LPPAQPSPSQSPPSQSYLAPTPSYSSS-----------SSSSQSYLSHSQSYLPSSQASP 232 Query: 857 IQPPSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGLLGTQPPAGPQNLPPLSIPNQ 916 +P + S LL PP+ P + Q P Q A P+ P P + Sbjct: 233 SRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQE 292 Query: 917 RMP---TMPMLDIRPGLIPQAPG-PRFPLI----------QPGIPPQRGIPPPSVLDSAL 962 + +L ++ PG + P++ + +P +P + Sbjct: 293 QQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPP 352 Query: 963 HPPPRGPFPP 972 PPP PP Sbjct: 353 LPPPNEEVPP 362 Score = 31.2 bits (69), Expect = 6.6 Identities = 29/110 (26%), Positives = 40/110 (36%), Gaps = 14/110 (12%) Query: 873 PPNIPNNSGLVGVQPPNVPNTPGLLGTQPPAGPQNLPPLSIPNQRMPTMPMLDIRPGLIP 932 PP +P V P PG + PA P + +S Q + + L Sbjct: 16 PPPVPPPPP---VALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQM 72 Query: 933 QAPGPRFPLIQPGIPPQRGIPPPSVLDSALH-----PPPRGPFPPGDIFS 977 Q ++QP P +PPP V+ + PPP P PPG S Sbjct: 73 QC------VLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALS 116 >gi|4508017 zinc finger protein 207 isoform a [Homo sapiens] Length = 478 Score = 67.0 bits (162), Expect = 1e-10 Identities = 92/388 (23%), Positives = 134/388 (34%), Gaps = 71/388 (18%) Query: 614 TTQSPTPVEKETVVTTQAEVFPPPVAMLQIPVAPAVPTVSLVPPAFPVSMP-VPP--PGF 670 T+ P PV+ + + + PP+A +P P P + PP P MP VPP PG Sbjct: 125 TSFQPQPVQPQ-------QGYIPPMAQPGLPPVPGAPGM---PPGIPPLMPGVPPLMPGM 174 Query: 671 SPIPP--PPFLRASFNPSQPPPGF----------MPPPVPPPVVPPPTI----------- 707 P+ P PP + P PG MPPPVP P +PP T Sbjct: 175 PPVMPGMPPGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILN 234 Query: 708 -PPVVPTSLVQPSLSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEP 766 PP ++ P +T G + S AS+ + S + T QA+ Sbjct: 235 RPPAPTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQA 294 Query: 767 EEKVPHLIDHQISSGENTRSVIPNDISSNAAILGGQPPNVTSNSGILGVQRPNVSSNSEI 826 + P D + + + P + A T+NS +P S S Sbjct: 295 AVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNST---AAKPAASITS-- 349 Query: 827 LGVRPSNVSSSSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQ 886 +P+ ++++S P+ + Q P + G P P + G+ Sbjct: 350 ---KPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMM 406 Query: 887 PPN--VPNTPGLLGTQPPAGPQNLPPLSIPNQRMPTMPMLDIRPGLIPQAPGPRFPLIQP 944 PP +P G+ PP G +P MP P GP P Sbjct: 407 PPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMP---------PYGQGP------P 451 Query: 945 GIPPQRGIPPPSVLDSALHPPPRGPFPP 972 +PP +G PP PP G PP Sbjct: 452 MVPPYQGGPP---------RPPMGMRPP 470 Score = 37.7 bits (86), Expect = 0.070 Identities = 42/154 (27%), Positives = 54/154 (35%), Gaps = 21/154 (13%) Query: 905 PQNLPPLS--IPNQRMPTMPMLDIRPGLIPQAPG--PRFPLIQPGIPPQRGIPPPSVLDS 960 PQ + P IP P +P + PG+ P P P P + PG+PP PP ++ Sbjct: 129 PQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGMM-- 186 Query: 961 ALHPPPRGPFPPGDIFSQPERPFLAPGRQSVDNVTNPEKRIPLGNDNIQQEGDRDYRFPP 1020 P G PPG P P L PG P IP PP Sbjct: 187 ----PMGGMMPPG-----PGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPP 237 Query: 1021 IETRESISRPPPVDVRDVVGRPIDPREGPGRPPL 1054 T + PPV +P+ P G P+ Sbjct: 238 APTATVPAPQPPVT------KPLFPSAGQMGTPV 265 >gi|9558733 transformer-2 alpha [Homo sapiens] Length = 282 Score = 66.6 bits (161), Expect = 1e-10 Identities = 51/166 (30%), Positives = 79/166 (47%), Gaps = 10/166 (6%) Query: 398 SRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRKRSRSRSRERKRKSSRSYSSE-RRARERE 456 SR HS S SRS K RSRSR S +R R RS S S R+R SRSY+ E RR R R Sbjct: 40 SRVSKHSESHSRSRSKSRSRSRRHSHRRYTRSRSHSHS-HRRRSRSRSYTPEYRRRRSRS 98 Query: 457 KERQKKGLPPIRSKTLSVCSTTLWVGQVDKKATQQDLTNLFEEFGQIESINMI------P 510 S+ +T L V + T++DL +F +G + +N++ Sbjct: 99 HSPMSNRRRHTGSRANPDPNTCLGVFGLSLYTTERDLREVFSRYGPLSGVNVVYDQRTGR 158 Query: 511 PRGCAYVCMVHRQDAFRALQKLSSGSYKIGSKVIKIAWALNKGVKT 556 RG A+V D+ A+++ + ++ + I++ +++ K T Sbjct: 159 SRGFAFVYFERIDDSKEAMER--ANGMELDGRRIRVDYSITKRAHT 202 >gi|4759098 splicing factor, arginine/serine-rich 10 [Homo sapiens] Length = 288 Score = 66.6 bits (161), Expect = 1e-10 Identities = 52/173 (30%), Positives = 87/173 (50%), Gaps = 12/173 (6%) Query: 389 QEAKKVAVRSRSRTHSRSRSRSPRKRRSRSRSGSRK--RKHRKRSRSRSRERKRKSSRSY 446 + A+ RSRS+ SR RSRS + RS SRS SR+ R+H RSRSRSR +R SRSY Sbjct: 28 KSARHTPARSRSKEDSR-RSRSKSRSRSESRSRSRRSSRRHYTRSRSRSRSHRRSRSRSY 86 Query: 447 SSE-RRAREREKERQKKGLPPIRSKTLSVCSTTLWVGQVDKKATQQDLTNLFEEFGQIES 505 S + RR + ++ + L V + T++DL +F ++G I Sbjct: 87 SRDYRRRHSHSHSPMSTRRRHVGNRANPDPNCCLGVFGLSLYTTERDLREVFSKYGPIAD 146 Query: 506 INMI------PPRGCAYVCMVHRQDAFRALQKLSSGSYKIGSKVIKIAWALNK 552 ++++ RG A+V + DA A ++ + ++ + I++ +++ K Sbjct: 147 VSIVYDQQSRRSRGFAFVYFENVDDAKEAKER--ANGMELDGRRIRVDFSITK 197 >gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] Length = 1682 Score = 65.9 bits (159), Expect = 2e-10 Identities = 112/431 (25%), Positives = 151/431 (35%), Gaps = 71/431 (16%) Query: 660 PVSMPVPPPGFSP------IPPPPFLRASFNPSQP--PPGFM--PPPVPPPVVPPPTIPP 709 PV PVPP S + P R N Q PPG PPP+PPP PPP PP Sbjct: 204 PVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPPLPPPPPPPPPPPP 263 Query: 710 VVPTSLVQPSLSMTPETVKDVGFGSLVIP--GGSVASNLATS--ALPAGNVFNAPTKQAE 765 +P P +T + G P GS +LP + AP A Sbjct: 264 PLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLPHPYPYPAPAYTAH 323 Query: 766 PEEKVPHLIDHQISSGENTRSVIPNDISSNAAILGGQPPNVTSNSGILGVQRPNVSSNSE 825 P H + G R P S+ + +PP S+ VQR + S+ Sbjct: 324 PP---GHRLVPAAPPGPGPR---PPGAESHGCLPATRPPG--SDLRESRVQRSRMDSS-- 373 Query: 826 ILGVRPSNVSSSSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGLVGV 885 V P+ ++ ++PP + G S S+++GL GV P N G+ G Sbjct: 374 ---VSPAATTACVPYAPSRPPGL---PGTTTSSSSSSSSNTGLRGVEP-----NPGIPGA 422 Query: 886 QPPNVP----NTPGLLGTQPPAGPQNLPPLSIPNQRMPTMPMLDIRPGLIPQAPGPRFPL 941 P + G LG P A P L P P L + PG P P L Sbjct: 423 DHYQTPALEVSHHGRLG--PSAHSSRKPFLGAP----AATPHLSLPPGPSSPPPPPCPRL 476 Query: 942 IQPGIPPQRGIPPPSV------------LDSALHPPPR---GPFPPGDIFSQPERPFLAP 986 ++P PP + P+ L PPR P P + F P + Sbjct: 477 LRPP-PPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSV 535 Query: 987 GRQSVDNVTNPEKRIPLGNDNIQQEGDRDYRFPPIETRESISRPPPVDVR---DVVGRPI 1043 G Q D+ T P P + + G +S PPP + D + RP Sbjct: 536 GTQ--DSHTPPTPPTPTTSSSNSNSGSHS-----SSPAGPVSFPPPPYLARSIDPLPRPP 588 Query: 1044 DPREGPGRPPL 1054 P + P PPL Sbjct: 589 SPAQNPQDPPL 599 Score = 41.2 bits (95), Expect = 0.006 Identities = 35/98 (35%), Positives = 41/98 (41%), Gaps = 18/98 (18%) Query: 602 VKSSEPVKETVQTTQSPTPVEKETVVTTQAEVFPPPVAMLQIPVAPAVPTVSLVPPAFPV 661 V P+KE + QSP P + T TT A P VA+ T + A Sbjct: 719 VAPQPPLKEPFASLQSPFPTD--TAPTTTA----PAVAVT------TTTTTTTTTTATQE 766 Query: 662 SMPVPPPGFSPIPPPPFLRASFNPSQPPPGFMPPPVPP 699 PPP +PPPP L PSQP P PPP PP Sbjct: 767 EEKKPPPA---LPPPPPLAKFPPPSQPQP---PPPPPP 798 Score = 40.8 bits (94), Expect = 0.008 Identities = 27/75 (36%), Positives = 33/75 (44%), Gaps = 2/75 (2%) Query: 644 PVAPAVPTVSLVPPAFPVSMPVPPPGFSPIPPPPFLRASFNPSQPPPGFMPPPVPPPVVP 703 P P PT S + S P G PPPP+L S +P PP P PP+VP Sbjct: 543 PPTPPTPTTSS-SNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVP 601 Query: 704 -PPTIPPVVPTSLVQ 717 +PP P+S Q Sbjct: 602 LTLALPPAPPSSCHQ 616 Score = 40.4 bits (93), Expect = 0.011 Identities = 95/385 (24%), Positives = 131/385 (34%), Gaps = 113/385 (29%) Query: 677 PFLRASFNPSQPPPGFMPPPVPPPVVPPPTIPPVVPTSLVQPSLSMTPETVKDVGFGSLV 736 P L PS PPP PP P + PPP PP + E ++++ FG+ Sbjct: 457 PHLSLPPGPSSPPP----PPCPRLLRPPP--PPAWLKGPACRAAREDGEILEELFFGTEG 510 Query: 737 IPGGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDHQISSGENTRSVIPNDISSNA 796 P A LP F P + S G P Sbjct: 511 PP------RPAPPPLPHREGFLGPPAS-------------RFSVGTQDSHTPPT------ 545 Query: 797 AILGGQPPNVTSNSGILGVQRPNVSSNSEILGVRPSNVSSSSGIIAAQPPNILNNSGILG 856 PP T++S +SNS S+ SS +G ++ PP L S Sbjct: 546 ------PPTPTTSSS---------NSNSG------SHSSSPAGPVSFPPPPYLARSIDPL 584 Query: 857 IQPPSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGLLGTQPPAGPQNLPPLSIPNQ 916 +PPS P P + PP VP T L PPA P + + + Sbjct: 585 PRPPS-----------PAQNPQD-------PPLVPLTLAL----PPAPPSSCHQNTSGSF 622 Query: 917 RMPTMPMLDIRPGLIPQAPGPRFPLIQPGIPPQRGIPPPSVLDSALHP--------PPRG 968 R P P P+ P+ P + PG PPP L A P P RG Sbjct: 623 RRPESPR--------PRVSFPKTPEVGPG-------PPPGPLSKAPQPVPPGVGELPARG 667 Query: 969 P----FPPGDIFSQPERPFLAPGRQSVDNVTNPEKRIPLGNDNIQQEGDRDYR------F 1018 P FPP + Q E P A + D + N K + +++I++E ++ Sbjct: 668 PRLFDFPPTPLEDQFEEP--AEFKILPDGLANIMKML---DESIRKEEEQQQHEAGVAPQ 722 Query: 1019 PPI-ETRESISRPPPVDVRDVVGRP 1042 PP+ E S+ P P D P Sbjct: 723 PPLKEPFASLQSPFPTDTAPTTTAP 747 Score = 38.1 bits (87), Expect = 0.054 Identities = 51/225 (22%), Positives = 76/225 (33%), Gaps = 75/225 (33%) Query: 574 EKVKVDDLEGFAEGGMIDQETVNTEWETVKSSEPVKETVQTTQSP-------TPVEKETV 626 E ++ ++ + E G+ Q + + +++S P +T TT +P T T Sbjct: 704 ESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPT-DTAPTTTAPAVAVTTTTTTTTTTT 762 Query: 627 VTTQAEVFPPPVAMLQIPVA----PAVPTVSLVPPAFPVSM------------------- 663 T + E PPP P+A P+ P PP P S+ Sbjct: 763 ATQEEEKKPPPALPPPPPLAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTG 822 Query: 664 ----------------PVPPPGFSPIPPP---PFLRASFNPS------------------ 686 P PP G + +PP P + S PS Sbjct: 823 AAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARER 882 Query: 687 ----QPPPGFMPPPVPPPVVPPPTIPPVVPTSLVQPSLSMTPETV 727 +P PG M P PP PP ++PP S V +S ET+ Sbjct: 883 RAGEEPVPGPMTPTQPP---PPLSLPPARSESEVLEEISRACETL 924 Score = 37.7 bits (86), Expect = 0.070 Identities = 33/92 (35%), Positives = 34/92 (36%), Gaps = 3/92 (3%) Query: 635 PPPVAMLQIPVAPAVPTVSLVPPAFPVSMPVPPPGFSPIPPPPFLRASFNPSQPPPGFMP 694 P P Q P P VP +PPA P S G P P R SF P P G P Sbjct: 588 PSPAQNPQDP--PLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSF-PKTPEVGPGP 644 Query: 695 PPVPPPVVPPPTIPPVVPTSLVQPSLSMTPET 726 PP P P P P V P L P T Sbjct: 645 PPGPLSKAPQPVPPGVGELPARGPRLFDFPPT 676 >gi|33620745 pre-mRNA cleavage complex II protein Pcf11 [Homo sapiens] Length = 1555 Score = 65.9 bits (159), Expect = 2e-10 Identities = 106/496 (21%), Positives = 206/496 (41%), Gaps = 68/496 (13%) Query: 22 SKAKMTQITKAAIKAIKFYKHVVQSVEKFIQKCKPEYKVPGLYVIDSIVRQSRHQFGQEK 81 SK + +T A + + F K +V +E K K+P +Y++DSIV+ G+E Sbjct: 33 SKPHINMLTILAEENLPFAKEIVSLIEAQTAKAPSSEKLPVMYLMDSIVKN----VGRE- 87 Query: 82 DVFAPRFSNNIISTFQNLYRCPGDDKSK-IVRVLNLWQK----NNVFKSEIIQPLLDMAA 136 + F+ N+++TF ++ ++ K + ++ + W + ++ ++ LD A Sbjct: 88 --YLTAFTKNLVATFICVFEKVDENTRKSLFKLRSTWDEIFPLKKLYALDVRVNSLDPAW 145 Query: 137 GI---PPPVVTPVLASTTTAMSNTPGTPVTPVTPANVVQGLPDPWVSQIT-NTDTLAAVA 192 I PP V T + ++ +P P TP T + P V I N + Sbjct: 146 PIKPLPPNVNTSSIHVNPKFLNKSPEEPSTPGTVVSSPSISTPPIVPDIQKNLTQEQLIR 205 Query: 193 QILQSPQGQ--QLQQLIQTLQIQQQKPQPSI---LQALDAGL---VVQLQALTAQLTAAA 244 Q L + Q Q +LQQ L+++Q K Q ++ +Q + L + +Q+ A Sbjct: 206 QQLLAKQKQLLELQQKKLELELEQAKAQLAVSLSVQQETSNLGPGSAPSKLHVSQIPPMA 265 Query: 245 AAANTLTPLE---------------QGVSFNKKL--MDRFDFGEDSEHSEE--------- 278 A P++ +G + + +L + + G+D H +E Sbjct: 266 VKAPHQVPVQSEKSRPGPSLQIQDLKGTNRDPRLNRISQHSHGKDQSHRKEFLMNTLNQS 325 Query: 279 ---PKKEIPASQLSHVSESVNNSIFHQIAEQLQQQNLEHLRQQLLEQQQPQKATP-QDSQ 334 K IP+ +L+ + + S E++ ++ L+ L + + + + +P ++ Sbjct: 326 DTKTSKTIPSEKLNSSKQEKSKS-----GEKITKKELDQLDSK--SKSKSKSPSPLKNKL 378 Query: 335 EGTFGSEHSASPSQGSSQQHFLEPEV--NLDDSIDIQQQDMDIDEGQDGVEEEVFEQEAK 392 T ++ S S S + +P + +L D D +D D+ E + E++ ++ K Sbjct: 379 SHTKDLKNQESESMRLSDMNKRDPRLKKHLQDKTD--GKDDDVKEKRKTAEKKDKDEHMK 436 Query: 393 KVAVR---SRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRKRSRSRSRERKRKSSRSYSSE 449 R SR++ + + + G++ + R RSRSR K +S +S + Sbjct: 437 SSEHRLAGSRNKIINGIVQKQDTITEESEKQGTKPGRSSTRKRSRSRSPKSRSPIIHSPK 496 Query: 450 RRAREREKERQKKGLP 465 RR R K RQ+ P Sbjct: 497 RRDRRSPKRRQRSMSP 512 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 65.1 bits (157), Expect = 4e-10 Identities = 100/392 (25%), Positives = 133/392 (33%), Gaps = 78/392 (19%) Query: 607 PVKETVQTTQSPTPVEKETVVTTQAEVFPPPVAMLQIPVAPAVPTVSLVPPAFPVSMPVP 666 P +Q+ T + T+ T + + PP++ L P A P ++L P P S P Sbjct: 355 PSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPAS 414 Query: 667 PPGFSPIPPPP----------FLRASFNPSQPPPGFMP--PPVPPPVVPPPTIPPVVPTS 714 PP SP+ P L+A F+P PP P PP PPV P T P P S Sbjct: 415 PP-LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPS 473 Query: 715 LVQPSLSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLI 774 L P L + P P LA L P QA P P L Sbjct: 474 LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAK----PPPQAPPALATPPL- 528 Query: 775 DHQISSGENTRSVIPNDISSNAAILGGQPPNVTSNSGILG------VQRPNVSSNSEILG 828 + S A GQ P S S + Q P V + + +L Sbjct: 529 ---------------QALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLA-APLLQ 572 Query: 829 VRPSNVSSSSGIIAAQPPNILNNSGILGIQ-----------PPSVSNSSGLLGVLPPNIP 877 V PS +S + +PP ++ + G + PPS S SS L G P++ Sbjct: 573 VPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSG---PDLA 629 Query: 878 NNSGLVGVQPPNVPNTPGLLGTQPPAGPQNLPPLSIPNQRMPTMPMLDIRPGLIPQAPGP 937 +S P + + P G PP P + P + P P Sbjct: 630 GHSSSATSTPEELRG----YDSGPEGGAAASPP--------PDAELAACHPAAWSRGPAP 677 Query: 938 RFPLIQPGIPPQRGIPPPSVLDSALHPPPRGP 969 PL G P G P P PP GP Sbjct: 678 --PLAFRGAP---GAPLP-------WPPATGP 697 Score = 58.2 bits (139), Expect = 5e-08 Identities = 119/489 (24%), Positives = 167/489 (34%), Gaps = 103/489 (21%) Query: 605 SEPVKETVQTTQSP--TPVEKETV-----VTTQAEVFPPPVAMLQI---PVAPAVPTVSL 654 S+P + +Q + P TP K+ +++ P P A LQ P PA P S Sbjct: 270 SQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSS 329 Query: 655 VPPAFPVSMPVPPPGFSPIPPPPFLRASFNPSQPPP---------------GFMP-PPVP 698 + +P+ PP P PP P+ PP F+P PP+ Sbjct: 330 LTCQLATPLPLAPPS--PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLS 387 Query: 699 PPVVPPPTIPPVVPTSLVQPSLSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFN 758 P PPP PP +L P L P L P + LA L A F+ Sbjct: 388 PLATPPPQAPP----ALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQA--PFS 441 Query: 759 APTKQAEPEEKVPHLIDHQISSGENTRSVIPNDISSNAAILGGQPPNVTSNSGILGVQRP 818 P P + P S + V P+ + A PP++ + Sbjct: 442 PP---PSPPVQAPF-------SPPASPPVSPSATPPSQA-----PPSLAAPP-------- 478 Query: 819 NVSSNSEILGVRPSNVSSSSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPN 878 L V PS +S +A PP PP ++ L PP P Sbjct: 479 --------LQVPPSPPASPPMSPSATPP---------PQAPPPLAAPPLQLAKPPPQAPP 521 Query: 879 NSGLVGVQPPNVPNTPGLLGTQPPAGPQ-NLP--PLSIPNQRMPTM---PMLDIRPGLIP 932 +Q +P+ P Q P P +LP PL+ P + P + P+L + P P Sbjct: 522 ALATPPLQA--LPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPS-PP 578 Query: 933 QAPGPRFPLIQPGIPPQRGIPPPSV-LDSALHPPPRGPFPPGDIFSQPERPFLAPGRQSV 991 +P + P P P + P + L A PPP P S P+ G S Sbjct: 579 ASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPD----LAGHSSS 634 Query: 992 DNVTNPEKRIPLGNDNIQQEGDRDYRFPPIETRESISRP--------PPVDVRDVVGRPI 1043 T E R G D+ + G PP + + P PP+ R G P+ Sbjct: 635 ATSTPEELR---GYDSGPEGGAA--ASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPL 689 Query: 1044 --DPREGPG 1050 P GPG Sbjct: 690 PWPPATGPG 698 Score = 51.6 bits (122), Expect = 5e-06 Identities = 100/425 (23%), Positives = 137/425 (32%), Gaps = 89/425 (20%) Query: 653 SLVPPAFPVSMPVPPPGFSPIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPP-----PTI 707 SL A P+S P + P RA +PSQP P + PP V PP P + Sbjct: 241 SLSSSATPLSSPARSGPSARGTP----RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL 296 Query: 708 PPVVPTSLVQPS-----LSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTK 762 P+ + L PS S P T+ S S+ LAT P Sbjct: 297 GPLSSSPLATPSPSAALQSQAPPTLPATPHSS------SLTCQLAT-----------PLP 339 Query: 763 QAEPEEKVPHLIDHQISSGENTRSVIPNDISSNAAILGGQPPNVTSNSGILGVQRPNVSS 822 A P P + +P+ PP + + P + + Sbjct: 340 LAPPSPSAPPSL-----------QTLPS------------PPATPPSQATTSLGSPTLQA 376 Query: 823 NSEILGVRPSNVSSSSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGL 882 L PS S Q P L + P S L P PN + Sbjct: 377 THSFL---PSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAV 433 Query: 883 VGVQPP--NVPNTPGLLGTQPPAGPQNLPPLSIPNQRMPTMPMLDIRPGLIPQAPGPRFP 940 +Q P P+ P PPA P P + P+Q P+ L P +P +P P P Sbjct: 434 HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPS---LAAPPLQVPPSP-PASP 489 Query: 941 LIQPGIPPQRGIPPPSVLD--SALHPPPRGP----FPPGDIFSQPERPFLAPGRQSVDNV 994 + P P PPP PPP+ P PP + + P P PG+ Sbjct: 490 PMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPP--LQALPSPPASFPGQAPF--- 544 Query: 995 TNPEKRIPLGNDNIQQEGDRDYRFPPIETRESISRPPPVDVRDVVGRPIDPR-EGPGRPP 1053 +P +P+ + PP+ + PP P P + P RPP Sbjct: 545 -SPSASLPM-----SPLATPPPQAPPVLAAPLLQVPP--------SPPASPTLQAPRRPP 590 Query: 1054 LDGRD 1058 G D Sbjct: 591 TPGPD 595 Score = 38.1 bits (87), Expect = 0.054 Identities = 91/425 (21%), Positives = 138/425 (32%), Gaps = 71/425 (16%) Query: 681 ASFNPSQPPPGFMPP-PVPPPVVPPPTIPPVVPTSLVQPSLSMTPETVKDVGFGSLVIP- 738 A+ P+ PG + P P P PPP P + ++ P + G G IP Sbjct: 13 AARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPE 72 Query: 739 ----------GGSVASNLATSALPAGNVFNA-PTKQAEP-------------------EE 768 G+ + N A+ +G A P K P ++ Sbjct: 73 SAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQK 132 Query: 769 KVPHLIDHQISSGENTRSVIPNDISSNAAILGGQPPNVTSNSGI----------LGVQRP 818 + + ++ G+ T + + +S+ A P T + + +G+ RP Sbjct: 133 GLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRP 192 Query: 819 NVSSNSEILGVRP-SNVSSSSGIIAAQPPNILNN--SGILGIQPPSVSNSSGLLGVLPPN 875 S+ P +VSS+S +P S G+Q P+ + S P + Sbjct: 193 APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS--SATPLS 250 Query: 876 IPNNSGLVGVQPPNVPNTPGLLGTQP-PAGPQNLPPLSIPNQRMPTMPMLDIRPGLIPQA 934 P SG P P P +QP P G Q L P + R P L Sbjct: 251 SPARSGPSARGTPRAPAHP----SQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLAT 306 Query: 935 PGPRFPLIQPGIPPQRGIPPPSVLDSALHPP----PRGPFPPGDIFSQPERPFLAPGRQS 990 P P L P P S L L P P P P + + P P P + + Sbjct: 307 PSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAT 366 Query: 991 VDNVTNPEKRIPLGNDNIQQEGDRDYRFPPIETRESISRPPPVDVRDVVGRPID-PREGP 1049 LG+ +Q + F P ++ PPP + P+ P P Sbjct: 367 TS----------LGSPTLQ----ATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPP 412 Query: 1050 GRPPL 1054 PPL Sbjct: 413 ASPPL 417 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 65.1 bits (157), Expect = 4e-10 Identities = 100/392 (25%), Positives = 133/392 (33%), Gaps = 78/392 (19%) Query: 607 PVKETVQTTQSPTPVEKETVVTTQAEVFPPPVAMLQIPVAPAVPTVSLVPPAFPVSMPVP 666 P +Q+ T + T+ T + + PP++ L P A P ++L P P S P Sbjct: 316 PSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPAS 375 Query: 667 PPGFSPIPPPP----------FLRASFNPSQPPPGFMP--PPVPPPVVPPPTIPPVVPTS 714 PP SP+ P L+A F+P PP P PP PPV P T P P S Sbjct: 376 PP-LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPS 434 Query: 715 LVQPSLSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLI 774 L P L + P P LA L P QA P P L Sbjct: 435 LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAK----PPPQAPPALATPPL- 489 Query: 775 DHQISSGENTRSVIPNDISSNAAILGGQPPNVTSNSGILG------VQRPNVSSNSEILG 828 + S A GQ P S S + Q P V + + +L Sbjct: 490 ---------------QALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLA-APLLQ 533 Query: 829 VRPSNVSSSSGIIAAQPPNILNNSGILGIQ-----------PPSVSNSSGLLGVLPPNIP 877 V PS +S + +PP ++ + G + PPS S SS L G P++ Sbjct: 534 VPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSG---PDLA 590 Query: 878 NNSGLVGVQPPNVPNTPGLLGTQPPAGPQNLPPLSIPNQRMPTMPMLDIRPGLIPQAPGP 937 +S P + + P G PP P + P + P P Sbjct: 591 GHSSSATSTPEELRG----YDSGPEGGAAASPP--------PDAELAACHPAAWSRGPAP 638 Query: 938 RFPLIQPGIPPQRGIPPPSVLDSALHPPPRGP 969 PL G P G P P PP GP Sbjct: 639 --PLAFRGAP---GAPLP-------WPPATGP 658 Score = 55.1 bits (131), Expect = 4e-07 Identities = 113/449 (25%), Positives = 153/449 (34%), Gaps = 95/449 (21%) Query: 635 PPPVAMLQIPVAPAVPTVSLVPPAFPVSMPVPPPGFSPIPPPPFLRASFNPSQPPP---- 690 PP V + APA+ +S P A P P PP SP PP P+ PP Sbjct: 273 PPQVTPPRKDAAPALGPLSSSPLATP--SPSAPP--SPSAPPSLQTLPSPPATPPSQATT 328 Query: 691 -----------GFMP-PPVPPPVVPPPTIPPVVPTSLVQPSLSMTPETVKDVGFGSLVIP 738 F+P PP+ P PPP PP +L P L P L P Sbjct: 329 SLGSPTLQATHSFLPSPPLSPLATPPPQAPP----ALALPPLQAPPSPPASPPLSPLATP 384 Query: 739 GGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDHQISSGENTRSVIPNDISSNAAI 798 + LA L A F+ P P + P S + V P+ + A Sbjct: 385 SPQAPNALAVHLLQA--PFSPP---PSPPVQAPF-------SPPASPPVSPSATPPSQA- 431 Query: 799 LGGQPPNVTSNSGILGVQRPNVSSNSEILGVRPSNVSSSSGIIAAQPPNILNNSGILGIQ 858 PP++ + L V PS +S +A PP Sbjct: 432 ----PPSLAAPP----------------LQVPPSPPASPPMSPSATPP---------PQA 462 Query: 859 PPSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGLLGTQPPAGPQ-NLP--PLSIPN 915 PP ++ L PP P +Q +P+ P Q P P +LP PL+ P Sbjct: 463 PPPLAAPPLQLAKPPPQAPPALATPPLQA--LPSPPASFPGQAPFSPSASLPMSPLATPP 520 Query: 916 QRMPTM---PMLDIRPGLIPQAPGPRFPLIQPGIPPQRGIPPPSV-LDSALHPPPRGPFP 971 + P + P+L + P P +P + P P P + P + L A PPP Sbjct: 521 PQAPPVLAAPLLQVPPS-PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRS 579 Query: 972 PGDIFSQPERPFLAPGRQSVDNVTNPEKRIPLGNDNIQQEGDRDYRFPPIETRESISRP- 1030 P S P+ G S T E R G D+ + G PP + + P Sbjct: 580 PSSTLSGPD----LAGHSSSATSTPEELR---GYDSGPEGGAA--ASPPPDAELAACHPA 630 Query: 1031 -------PPVDVRDVVGRPI--DPREGPG 1050 PP+ R G P+ P GPG Sbjct: 631 AWSRGPAPPLAFRGAPGAPLPWPPATGPG 659 Score = 48.5 bits (114), Expect = 4e-05 Identities = 103/426 (24%), Positives = 136/426 (31%), Gaps = 100/426 (23%) Query: 653 SLVPPAFPVSMPVPPPGFSPIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPP-----PTI 707 SL A P+S P + P RA +PSQP P + PP V PP P + Sbjct: 232 SLSSSATPLSSPARSGPSARGTP----RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL 287 Query: 708 PPVVPTSLVQPSLSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEPE 767 P+ + L PS S P +L P + S TS +PT QA Sbjct: 288 GPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTS-------LGSPTLQA--- 337 Query: 768 EKVPHLIDHQISSGENTRSVIPNDISSNAAILGGQPPNVTSNSGILGVQRPNVSSNSEIL 827 T S +P S + L PP + +Q P S L Sbjct: 338 ----------------THSFLP---SPPLSPLATPPPQAPPALALPPLQAPPSPPASPPL 378 Query: 828 GVRPSNVSSSSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQP 887 +A P N + +Q P PP+ P + P Sbjct: 379 SP-----------LATPSPQAPNALAVHLLQAPFSP---------PPSPPVQAPFS--PP 416 Query: 888 PNVPNTPGLLGTQPPAGPQNL--PPLSIPNQRMPTMPMLDIRPGLIPQAPGPRFPLIQPG 945 + P +P T P P +L PPL +P P P + PQAP P Sbjct: 417 ASPPVSPS--ATPPSQAPPSLAAPPLQVPPSP-PASPPMSPSATPPPQAPPPL------A 467 Query: 946 IPPQRGIPPPSVLDSALHPPP-------------RGPFPPGDIFSQPERPFLAPGRQSVD 992 PP + PP AL PP + PF P S P P P Q+ Sbjct: 468 APPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPS--ASLPMSPLATPPPQAPP 525 Query: 993 NVTNPEKRIPLGNDNIQQEGDRDYRFPPIETRESISRPP-PVDVRDVVGRPIDPREGPGR 1051 + P ++P P T ++ RPP P V G + PG Sbjct: 526 VLAAPLLQVPPSP-------------PASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP 572 Query: 1052 PPLDGR 1057 PP R Sbjct: 573 PPPPSR 578 Score = 45.8 bits (107), Expect = 3e-04 Identities = 59/222 (26%), Positives = 81/222 (36%), Gaps = 27/222 (12%) Query: 605 SEPVKETVQTTQSPTPVEKETVVTTQAEVFPPPVAMLQIPVAPAVPTVSLVPPAFPVSMP 664 S PV+ SP PV +QA PP +A + V P+ P + P+ Sbjct: 406 SPPVQAPFSPPASP-PVSPSATPPSQA---PPSLAAPPLQVPPSPPASPPMSPSATPPPQ 461 Query: 665 VPPPGFSP-----IPPP--------PFLRASFNPSQPPPGFMP------PPVPPPVVPPP 705 PPP +P PPP P L+A +P PG P P+ P PPP Sbjct: 462 APPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPP 521 Query: 706 TIPPVVPTSLVQ--PSLSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQ 763 PPV+ L+Q PS +P T++ P SV+ T AL G P++ Sbjct: 522 QAPPVLAAPLLQVPPSPPASP-TLQAPRRPPTPGPDTSVSGPRLTLALAPGPP-PPPSRS 579 Query: 764 AEPEEKVPHLIDHQISSGENTRSVIPNDISSNAAILGGQPPN 805 P L H S+ + D PP+ Sbjct: 580 PSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPD 621 Score = 43.9 bits (102), Expect = 0.001 Identities = 82/378 (21%), Positives = 122/378 (32%), Gaps = 70/378 (18%) Query: 681 ASFNPSQPPPGFMPPPVP-PPVVPPPTIPPVVPTSLVQPSLSMTPETVKDVGFGSLVIPG 739 A+ P+ PG + P P P PPP P + ++ P + G G IP Sbjct: 13 AARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPE 72 Query: 740 GSV-----------ASNLATSALPAGNVFNAP---------TKQAEP--EEKVPHLIDHQ 777 + AS A PA N P T + P ++ + + Sbjct: 73 SAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEET 132 Query: 778 ISSGENTRSVIPNDISSNAA------ILGGQPPNVTSNSGILGVQ--------------- 816 ++ G+ T + + +S+ A G P + S G + Sbjct: 133 VARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPP 192 Query: 817 ----RPNVSSNSEILGVRPSNVSS---SSGIIAAQPPNILNNSGILGIQPPSVSNSSGL- 868 R +VSS SE PS + S+G +P + +S + P+ S S Sbjct: 193 TEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARG 252 Query: 869 --LGVLPPNIPNNSGLVGVQPPNVPNTPGLLGTQPPAGPQNLPPLSIPNQRMPTMPMLDI 926 P+ P GL ++PP V TP P GP + PL+ P+ P P Sbjct: 253 TPRAPAHPSQPKPKGLQALRPPQV--TPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 Query: 927 RPGLIPQAPG-----PRFPLIQPGIPPQRGIPPPSVLDSALHPPPRGP---------FPP 972 +P P L P + P L PPP+ P PP Sbjct: 311 SLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPP 370 Query: 973 GDIFSQPERPFLAPGRQS 990 S P P P Q+ Sbjct: 371 SPPASPPLSPLATPSPQA 388 >gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain containing B [Homo sapiens] Length = 546 Score = 64.7 bits (156), Expect = 5e-10 Identities = 49/151 (32%), Positives = 77/151 (50%), Gaps = 19/151 (12%) Query: 345 SPSQGSSQQHFLEPEVNLDDSIDIQQQDMDIDEGQDGVEEEVFEQEAKKVAVRSRSRTHS 404 SP + S+ H E + S D ++++ ++ + +E E E+E ++ RS R Sbjct: 272 SPRRSRSRSHHREGHGS--SSFD---RELEREKERQRLEREAKEREKERRRSRSIDRGLE 326 Query: 405 RSRSRSPRKRRSRSRSGSRK--RKHRKRSRSRSRERKRKSSRSYSSER-RAREREKERQK 461 R RSRS + RSRSRS RK R+ R R R + ER R+ R Y ER RE+E+ER + Sbjct: 327 RRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSR 386 Query: 462 KGLPPIRSKTLSVCSTTLWVGQVDKKATQQD 492 + RS+ G+V++K ++D Sbjct: 387 ERSKEQRSR-----------GEVEEKKHKED 406 Score = 50.8 bits (120), Expect = 8e-06 Identities = 30/79 (37%), Positives = 41/79 (51%), Gaps = 4/79 (5%) Query: 388 EQEAKKVAVRSRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRKRSRSRS---RERKRKSSR 444 E E KK R H R R +K + SRS SR+RKHR RSRSR+ R R R + Sbjct: 397 EVEEKKHKEDKDDRRH-RDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEK 455 Query: 445 SYSSERRAREREKERQKKG 463 S + ++E+ +R + G Sbjct: 456 SSKHKNESKEKSNKRSRSG 474 Score = 50.8 bits (120), Expect = 8e-06 Identities = 34/103 (33%), Positives = 56/103 (54%), Gaps = 7/103 (6%) Query: 366 IDIQQQDMDIDEGQDGVEEEVFEQEAKKVAVRSRSRTH-SRSRSRSPRKRRSRSRSGSRK 424 ++ ++ D D+ + ++ ++E K RSR R H SRSRSR+ KR SRSRS + Sbjct: 398 VEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKR-SRSRSKEKS 456 Query: 425 RKHRKRSRSRSRERKRKSSRSYS-----SERRAREREKERQKK 462 KH+ S+ +S +R R S+ + S++R KE+ +K Sbjct: 457 SKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRK 499 Score = 50.1 bits (118), Expect = 1e-05 Identities = 42/116 (36%), Positives = 60/116 (51%), Gaps = 16/116 (13%) Query: 361 NLDDSIDIQQQDMDIDEGQDGVEEEVFEQEAKKVAVRSRSRTHSRSRSRSPRKRRSRSRS 420 N+D I + + + D G++G EE E + RSRS S S RSPR+ RSRS Sbjct: 228 NIDQQIKTRPRKIKKD-GKEGAEEIDRHVERR----RSRSPRRSLSPRRSPRRSRSRSH- 281 Query: 421 GSRKRKHRKRSRSRSRERKRKSSRSYSSERRAREREKERQK-----KGLPPIRSKT 471 + H S R ER+++ R ER A+EREKER++ +GL RS++ Sbjct: 282 --HREGHGSSSFDRELEREKERQRL---EREAKEREKERRRSRSIDRGLERRRSRS 332 Score = 49.7 bits (117), Expect = 2e-05 Identities = 33/97 (34%), Positives = 51/97 (52%), Gaps = 7/97 (7%) Query: 369 QQQDMDIDEGQDGVEEEVFEQEAKKVAVRSRSRTHSRSRS--RSPRKRRSRSRSGSRKRK 426 + +D D + G + +E +E K RSR + + R+ R R +++K Sbjct: 366 RDRDYDKERGNEREKERERSRERSKEQ-RSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKK 424 Query: 427 HRKRSRSRSRERKRKS-SRSYSSERRAREREKERQKK 462 H SRSRSRERK +S SRS ++ +R+R R KE+ K Sbjct: 425 H---SRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSK 458 Score = 45.8 bits (107), Expect = 3e-04 Identities = 43/132 (32%), Positives = 61/132 (46%), Gaps = 15/132 (11%) Query: 341 EHSASPSQGSSQQHFLEPEVNLDDSIDIQQQDMDIDEGQDGVEEEVFEQEAKKVAVRSRS 400 E S S+ + +E + + +D D + +D D ++ +E K RSRS Sbjct: 383 ERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKH---RSRS 439 Query: 401 RTHS---RSRSRSPRKRRSRSRSGSRKRKHRKRSRSRSR------ERKRKSSRSYSSER- 450 R+ + RSRSRS K +S K K KRSRS S+ E+ +K S S E+ Sbjct: 440 RSRNAGKRSRSRS--KEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKS 497 Query: 451 RAREREKERQKK 462 R R R KER K Sbjct: 498 RKRSRSKERSHK 509 Score = 43.1 bits (100), Expect = 0.002 Identities = 28/84 (33%), Positives = 42/84 (50%), Gaps = 5/84 (5%) Query: 383 EEEVFEQEAKKVAVRSRSRTHS----RSRSRSPRKRRSRSRSGSRKRKHRKRSRSRSRER 438 + E E+ K+ S+ RT S + R SP K +SR RS S++R H KR S S+++ Sbjct: 460 KNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSH-KRDHSDSKDQ 518 Query: 439 KRKSSRSYSSERRAREREKERQKK 462 K R S +EK+ + K Sbjct: 519 SDKHDRRRSQSIEQESQEKQHKNK 542 Score = 34.3 bits (77), Expect = 0.78 Identities = 35/173 (20%), Positives = 76/173 (43%), Gaps = 19/173 (10%) Query: 274 EHSEEPKKEIPASQLSHVSESVNNSIFHQIAEQLQQQNLEHLRQQLLEQQQPQKATPQDS 333 E S+E + + H + + H+ ++ ++ +H R + E++ ++ +++ Sbjct: 387 ERSKEQRSRGEVEEKKHKEDKDDRR--HRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNA 444 Query: 334 QEGTFGSEHSASPSQGSSQQHFLEPEVNLDDSIDIQQQDMDIDEGQDGVEEEVFEQEAKK 393 + S S S+ S +H E + ++ + G G + V E+ K+ Sbjct: 445 ------GKRSRSRSKEKSSKHKNESK---------EKSNKRSRSGSQGRTDSV-EKSKKR 488 Query: 394 VAVRSRSRTHSRSRSRSPRKRRSRSRSGSRKRKH-RKRSRSRSRERKRKSSRS 445 S+ ++ RSRS+ +R S S + KH R+RS+S +E + K ++ Sbjct: 489 EHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQHKN 541 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 64.3 bits (155), Expect = 7e-10 Identities = 108/451 (23%), Positives = 138/451 (30%), Gaps = 53/451 (11%) Query: 636 PPVAMLQIPVA-PAVPTV--SLVPPAFPVSMPVPPPGFSPIPPPPFLRASFNPSQPP--P 690 PP A P PA P+ + PPA P P +P P + P P P Sbjct: 988 PPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSP 1047 Query: 691 GFMPPPVPPPVVPPPTIP-----PVVPTSLVQPSL-SMTPETVKDVGFGSLVIPGGSVAS 744 P P P P T+P P P+ P+ + TP + K G + P G+ Sbjct: 1048 AATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPK--GGPATPSPKGAPMP 1105 Query: 745 NLATSALPAGNVFNAP------TKQAEPEEKVPHLIDHQISSGENTRSVIPNDISSNAAI 798 AT P G + P T A P L T + P S Sbjct: 1106 PAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATP---PSPKGG 1162 Query: 799 LGGQPPNVTSNSGILGVQRPNVSSNSEILGVRPSNVSSSSGIIAAQPPNILNNSGILGIQ 858 L PP + P + S G+ + + AA PP+ G+ Sbjct: 1163 LATPPPKGAPTT-------PAATPPSPKGGLATPSPKGAPTTPAATPPSPKG-----GLA 1210 Query: 859 PPSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGLLGTQPPAGPQNLPPLSIPNQRM 918 PS + PP+ GL P P TP P GP PP P Sbjct: 1211 TPSPKGAPTTPAATPPS--PKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPA 1268 Query: 919 PTMPMLDIRPGLIPQAPGPRFPLIQPGIP-------PQRGIP------PPSVLDSALHPP 965 T P L P P ++ P P P +G P PPS S PP Sbjct: 1269 ATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPP 1328 Query: 966 PRG-PFPPGDIFSQPERPFLAPGR--QSVDNVTNP-EKRIPLGNDNIQQEGDRDYRFPPI 1021 P+G P PP P+ P S T P K P PP Sbjct: 1329 PKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPS 1388 Query: 1022 ETRESISRPPPVDVRDVVGRPIDPREGPGRP 1052 R P D P+ P++ P P Sbjct: 1389 PKRGPAIPSPKGDPTSPAVIPLSPKKAPATP 1419 Score = 55.8 bits (133), Expect = 2e-07 Identities = 119/504 (23%), Positives = 140/504 (27%), Gaps = 111/504 (22%) Query: 630 QAEVFPPPVAMLQIPVAPAVPTVSLVPPAFPVSMPVPP-PGFSPIPP---PPFLRASFNP 685 +A P P + P PT P P P P P ++P PP PP + Sbjct: 920 KARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPAT 979 Query: 686 SQP-----PPGFMPP--------------PVPPPVVPPPTIPPVVPTSLVQPSLSMTPET 726 P PP PP P PP V PP P P + P + TP Sbjct: 980 PSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPS--PKGSPAATPFPKGASTPPA 1037 Query: 727 VKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDHQISSGENTRS 786 P GS A+ P P+ + P P L S Sbjct: 1038 ATPPS------PKGSPAATPLPKGAPTTPAATLPSPKGGP--ATPSLKGAPTPPAATPPS 1089 Query: 787 VIPNDISSNAAILGG-QPPNVTSNSGILGVQRPNVSSNSEILGVRPSNVSSSSGIIAAQP 845 P + + G PP T S G+ P P S G +A P Sbjct: 1090 --PKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATP---PSPKGGLATPP 1144 Query: 846 PNIL---------NNSGILGIQPPS----------VSNSSGLLGVLPPNIPN-------- 878 P + G L PP S GL P P Sbjct: 1145 PKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPS 1204 Query: 879 -NSGLVGVQPPNVPNTPGLLGTQPPAGPQNLPPLSIPNQRMPTMPMLDIRPGLIPQAPGP 937 GL P P TP P G P P T P P P P Sbjct: 1205 PKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAP 1264 Query: 938 RFPLIQP-------GIPPQRGIPPPSVL-------DSALHPPPRGPFPPGDIFSQPERPF 983 P P PP +G P P+V+ A PP P PP + P P Sbjct: 1265 TPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPA---ATPPSPK 1321 Query: 984 LAPGRQSVDNVTNPEKRIPLGNDNIQQEGDRDYRFPPIETRESISRPP--PVDVRDVVGR 1041 +PG T P K P PP T S P P G Sbjct: 1322 GSPG-------TPPPKGAPT---------------PPAVTPPSPKGTPTLPATTPSSKGG 1359 Query: 1042 PIDP--REGPGRPPLDGRDHFGRP 1063 P P +EGP PP H G P Sbjct: 1360 PTTPSSKEGP-TPPAATPSHKGGP 1382 Score = 55.5 bits (132), Expect = 3e-07 Identities = 110/464 (23%), Positives = 167/464 (35%), Gaps = 69/464 (14%) Query: 619 TPVEKETVVT-TQAEVFPPPVAMLQIPVAPAVPTVSLVPPAFPVSMPVP------PPGFS 671 TPV +E T ++ ++ PP V + + APA + PA P S P PP Sbjct: 1418 TPVTREGAATPSKGDLTPPAVTPVSLKKAPAT-SAPKGGPATPSSKGDPTLPAVTPPSPK 1476 Query: 672 PIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPP--PTIPPVVPTS------LVQPSLSM- 722 P P + S +P + P P P+ P +P P+ P VP + + P+ ++ Sbjct: 1477 EPPAPKQVATSSSPKKAPA--TPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLL 1534 Query: 723 ---TPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDHQIS 779 TP T+ +L+ P +V S T A+P AP + E P + Sbjct: 1535 SKKTPATLAPK--EALIPPAMTVPSPKKTPAIPTPK--EAPATPSSKEASSPPAVTPSTY 1590 Query: 780 SGENT--RSVIPNDISSNAAILGGQPPNVTSNSGILGVQRPNVSSNSEILGVRPSNVSSS 837 G + +IP ++S + PP VT S G P V PS++ S Sbjct: 1591 KGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDS 1650 Query: 838 SGIIAAQPPNILNNSGILGIQP----PSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVPNT 893 P ++ G Q P+ + L VL P ++ ++ P T Sbjct: 1651 ----PTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQT 1706 Query: 894 PGLLGTQPPAGPQNLPPLSIPNQRMPTMPMLDIRPGLIPQAPGPRFPLIQPGIPPQRGIP 953 T PP P P + + P L AP P P+ + +G Sbjct: 1707 KKSSATSPPICPD---PSAKNGSKGP----------LSTVAPAPLLPVQKDSSKTAKG-- 1751 Query: 954 PPSVLDSALHPPPRGPF-PPGDIFSQP------ERPFLAPGRQSVDNVTNPEKRIPLGND 1006 A H P+GP PP S P E+ P SV +P +PL Sbjct: 1752 -----KDASH-SPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPS 1805 Query: 1007 NIQQEGDRDYRFP--PIETRESISRP-PPVDVRDVVGRPIDPRE 1047 + + P P ES S+P P D +++ P+ P E Sbjct: 1806 PVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELL--PLIPPE 1847 Score = 53.5 bits (127), Expect = 1e-06 Identities = 103/438 (23%), Positives = 145/438 (33%), Gaps = 98/438 (22%) Query: 600 ETVKSSEPVKETVQTTQSPTPVEKETVVTTQAEVFPPPVAMLQIPVAPAV---------- 649 + SS P K P + ++ EV P + + P+AP Sbjct: 1483 QVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEV-PATPSSRRDPIAPTATLLSKKTPAT 1541 Query: 650 --PTVSLVPPAFPVSMP-----VPPPGFSPIPP-------PPFLRASFNPSQPPPG--FM 693 P +L+PPA V P +P P +P P PP + S P P + Sbjct: 1542 LAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLI 1601 Query: 694 PP----------PVPPPVVPP--------------PTIPPVVPTSLVQPSLSMTPETVKD 729 PP P PP V PP PT PPV P+SL S T K Sbjct: 1602 PPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCK- 1660 Query: 730 VGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDHQISSGENTRSVIP 789 +P S V AP ++ P +I G T+ Sbjct: 1661 ---MGATVPQASKGLPAKKGPTALKEVLVAPAPESTP------IITAPTRKGPQTKK--- 1708 Query: 790 NDISSNAAILGGQPPNVTSNSGILGVQRPNVSSNSEILGVRPSNVSSSSGIIAAQPPNIL 849 S+ + + P + G L P + +L V+ + ++ G A+ P Sbjct: 1709 --SSATSPPICPDPSAKNGSKGPLSTVAP-----APLLPVQKDSSKTAKGKDASHSP--- 1758 Query: 850 NNSGILGIQPPSVSNSSGLLG-----VLPPNIPNNSGLVGVQPPNVPNTPGLLGTQPPAG 904 G L PP S+ L VLP P ++ + P V P Sbjct: 1759 --KGPLA--PPESKASTPLTAAAFEKVLPK--PESASVSAAPSPPV---------SLPLA 1803 Query: 905 PQNLPPLSIPNQRMPTMPMLDIRPGLIPQAPGPRFPLIQPGIPPQ---RGIPPPSVLDSA 961 P +P L Q +P+ P L + P AP L+ P IPP+ G+P SVL + Sbjct: 1804 PSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELL-PLIPPEPISGGVPFQSVLVNM 1862 Query: 962 LHPPPRGPFPPGDIFSQP 979 P G P QP Sbjct: 1863 PTPKSAGIPVPTPSAKQP 1880 Score = 47.8 bits (112), Expect = 7e-05 Identities = 104/455 (22%), Positives = 143/455 (31%), Gaps = 64/455 (14%) Query: 628 TTQAEVFPPPVAMLQIPVAPAVPTVSLVPPAFPVSMPV-PPPGFSPIPP---PPFLRASF 683 TT A P P L P PT P P P PPP +P PP PP L+ Sbjct: 1219 TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGL 1278 Query: 684 NPSQPPPGFMPPPVPPPVVP------PPTIPP---VVPTSLVQPSLSMTPETVKDVGFGS 734 P P P V P P T PP P + PS +P T G+ Sbjct: 1279 ----ATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPK--GA 1332 Query: 735 LVIPGGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDHQISSGENTRSVIPNDISS 794 P + S T LPA P+ + P SS E P ++ Sbjct: 1333 PTPPAVTPPSPKGTPTLPA----TTPSSKGGPTTP---------SSKEG-----PTPPAA 1374 Query: 795 NAAILGGQPPNVTSNSGILGVQRPNVSSNSEILGVRPSNVSSSSGIIAAQPPNILNNSGI 854 + GG P +T S G P+ + V P + + + + G Sbjct: 1375 TPSHKGG--PAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKG- 1431 Query: 855 LGIQPPSV---------SNSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGLLGTQPPAGP 905 + PP+V + S+ G P+ + L V PP+ P + P Sbjct: 1432 -DLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSP 1490 Query: 906 QNLPPLSIPNQRMPTMP-MLDIRPGLIPQAPGPRFPLIQPGIPPQRGIPPPSVLDSALHP 964 + P P PT+P ++ P +P P R I P P ++ Sbjct: 1491 KKAPATPAP-MGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALI 1549 Query: 965 PPRGPFPPGDIFSQPERPFLAPGRQSVDNVTNPEKRIPLGNDNIQQEGDRDYRFPPIETR 1024 PP P P AP S ++P P + ++ PP T Sbjct: 1550 PPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTP--STYKGAPSPKELLIPPAVTS 1607 Query: 1025 ES---ISRPPPVDVRDVVGRPIDPREGPGRPPLDG 1056 S PP V P P +GP P G Sbjct: 1608 PSPKEAPTPPAV-------TPPSPEKGPATPAPKG 1635 Score = 45.4 bits (106), Expect = 3e-04 Identities = 85/388 (21%), Positives = 150/388 (38%), Gaps = 78/388 (20%) Query: 624 ETVVTTQAEVFPPPVAMLQIPVAPAV--------PTVSLVPPAFPVSMPVPPPG---FSP 672 ETV T+ E+ P +P++ A+ P +L PP P P SP Sbjct: 7 ETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASP 66 Query: 673 IPPP----------PFLRASFNPSQP------PPGFMPPPVPPPVVPPP---TIPPVVPT 713 P P PF ++S + P P F+P + PP+ P P + PT Sbjct: 67 FPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPT 126 Query: 714 SLVQPS-------LSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNV--FNAPTKQA 764 PS +++ P +V+ S P + S + + +G+V +AP + Sbjct: 127 LKGTPSSSAPLALVALAPHSVQK----SSAFPPNLLTSPPSVAVAESGSVITLSAPIAPS 182 Query: 765 EPEEKVPHLIDHQISSGENTRSVIPNDISSNAAILGGQPPNVTSNSGILGVQRPNVSSNS 824 EP+ + + + + + T S P I S P + SG+ + + ++ Sbjct: 183 EPKTNLNKVPSEVVPNPKGTPS--PPCIVSTVP-YHCVTPMASIQSGVASLPQTTPTTTL 239 Query: 825 EILGVRPSNVSSSSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLGVL-----------P 873 I + + + SS +I+ Q P L+ G + P ++S S+ L V+ P Sbjct: 240 AIASPQVKDTTISSVLISPQNPGSLSLKGPVS-PPAALSLSTQSLPVVTSSQKTAGPNTP 298 Query: 874 PNIPNNSG---------------LVGVQPPNVPNTPGLLGTQPPAGPQNLPPLSIPNQRM 918 P+ P + G L+G P+ + P + + + + S P+QR Sbjct: 299 PDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTV---KTISVDHSSTGASYPSQR- 354 Query: 919 PTMPMLDIRPGLIPQAPGPRFPLIQPGI 946 +P L R ++P A FP++ P + Sbjct: 355 SVIPPLPSRNEVVP-ATVAAFPVVAPSV 381 Score = 43.5 bits (101), Expect = 0.001 Identities = 96/434 (22%), Positives = 144/434 (33%), Gaps = 82/434 (18%) Query: 607 PVKETVQTTQSPTPVE-KETVVTTQAEVFPPPVAM--------LQIPVAPAVPTVSLVPP 657 P + TT + TP K T + P P A L P P ++V P Sbjct: 1235 PSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTP 1294 Query: 658 AFPVSMPVP-PPGFSPIPP---PPFLRASFNPSQPPPGFMPPPVPPPVVPP-----PTIP 708 P P PP +P PP PP + S P PPP P PP V PP PT+P Sbjct: 1295 PSPKGGPATSPPKGAPTPPAATPPSPKGS--PGTPPP--KGAPTPPAVTPPSPKGTPTLP 1350 Query: 709 ---------PVVPTSLVQPSLSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNA 759 P P+S P+ P G + P S P G+ + Sbjct: 1351 ATTPSSKGGPTTPSSKEGPT---PPAATPSHKGGPAMTPPSPKRGPAIPS--PKGDPTSP 1405 Query: 760 PTKQAEPEEKVPHLIDHQISSGENTRSVIPNDISSNAAILGGQPPNVTSNSGILGVQRPN 819 P++ + + ++ + + P ++ + + P ++ G G P+ Sbjct: 1406 AVIPLSPKKAPATPVTREGAATPSKGDLTPPAVT---PVSLKKAPATSAPKG--GPATPS 1460 Query: 820 VSSNSEILGVRPSNVSSSSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLG--VLPPNIP 877 + + V P + P + +S P + +G LP IP Sbjct: 1461 SKGDPTLPAVTPPSPKEPPA-----PKQVATSS-----SPKKAPATPAPMGAPTLPAVIP 1510 Query: 878 NNSGLVGVQP-----PNVP-------NTPGLLGTQ----PPA----GPQNLPPLSIPNQR 917 ++ V P P P TP L + PPA P+ P + P + Sbjct: 1511 SSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEA 1570 Query: 918 MPTMPMLD------IRPGLIPQAPGPRFPLIQPGI---PPQRGIPPPSVLDSALHPPPRG 968 T + + P AP P+ LI P + P+ PP+V + P Sbjct: 1571 PATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPAT 1630 Query: 969 PFPPGDIFSQPERP 982 P P G S P P Sbjct: 1631 PAPKGTPTSPPVTP 1644 Score = 38.9 bits (89), Expect = 0.032 Identities = 92/420 (21%), Positives = 139/420 (33%), Gaps = 51/420 (12%) Query: 576 VKVDDLEGFAEGGMIDQETVNTEWETVKSSEPVKETVQTTQSPTPVEKETVVTTQAEVFP 635 +K D G G + + ++ T ++ P++ +PT + + TT A F Sbjct: 621 IKTDSYAGPDSAGPLLKSSLITP---TVAAFPLESADPAGVAPTTAKGTSTYTTTASPFL 677 Query: 636 P----------PVAMLQIPVAPAVPTVSLVPPAFPVSMPVPPPGFSPIPPPPFLRASFNP 685 PV + P VPT S P P P + + P ++ +P Sbjct: 678 EGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSP 737 Query: 686 SQPPPGFMPPPVPPPVVPPPT--IPPVVPTSLVQPSLSMTPETVKDVGFGSLVIPGGSVA 743 S PP G PP T + + TS + P S E + S Sbjct: 738 SLPPAG----------TPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTL 787 Query: 744 SNLATSALPAGNVFNAPTKQAEPEEKVPHLIDHQISSGENTRSVIPNDIS----SNAAIL 799 + LA S P G V +P + P +K D I G + V P + S ++ + Sbjct: 788 TYLADSPSPLG-VSVSPQTKRPPTKKGSAGPDTPI--GNLSSPVSPVEASFLPENSLSFQ 844 Query: 800 GGQPPNVTSNSGILGVQRPNVSSNSEILGVRPSNVSSSSGIIAAQPPNILNNSGILGIQP 859 G + T++S P S PS V+ S PP ++ + Sbjct: 845 GSKDSPATTHS-------PTPPSPKG--APTPSAVTPLSPKGVTLPPKETPTPSVVNLPF 895 Query: 860 PSVSNSSGLLGVLPPNIPNNSGLVGVQ----PPNVPNTPGLLGTQPPAGPQNLPPLSIPN 915 P ++ P +S + P +P +P G P P PP Sbjct: 896 PKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGA--PTPPAATPPSPKGG 953 Query: 916 QRMPTMPMLDIRPGLIPQAP--GPRFPLIQPGIPPQRGIPPPSVLDSALHPPPRG-PFPP 972 P+ P P +P GP P G P PPS P P+G P PP Sbjct: 954 PATPSPKWAPTPPAATPPSPKGGPATP-SPKGAPTPPAATPPSPKGGPATPSPKGAPTPP 1012 Score = 37.0 bits (84), Expect = 0.12 Identities = 70/338 (20%), Positives = 114/338 (33%), Gaps = 60/338 (17%) Query: 658 AFPVSMPVPPPGFS------------PIPPP-PFLRASFNPSQPPPGFMPPPVPPPVVPP 704 AFP ++ PP + PI P P + PS+ P P PP +V Sbjct: 152 AFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVST 211 Query: 705 PTIPPVVPTSLVQPSLSMTPET------------VKDVGFGSLVIPGGSVASNLATSALP 752 V P + +Q ++ P+T VKD S++I S +L Sbjct: 212 VPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLI------SPQNPGSLS 265 Query: 753 AGNVFNAPTKQAEPEEKVPHLIDHQISSGENTRSVIPNDISSNAA-----------ILGG 801 + P + + +P + Q ++G NT P + S+ A +LG Sbjct: 266 LKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQ 325 Query: 802 QPPNVTSNSGILGVQRPNVS------SNSEILGVRPSNVSSSSGIIAAQPPNILNNSGIL 855 P+ S+ + + + S S ++ PS +AA P Sbjct: 326 TGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFP---------- 375 Query: 856 GIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGLLGTQPPAGPQNLPPLSIPN 915 + PSV + + + P+ S V P T +L + P A +P Sbjct: 376 -VVAPSVDKGPSTISSITCS-PSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPV 433 Query: 916 QRMPTMPMLDIRPGLIPQAPGPRFPLIQPGIPPQRGIP 953 + T P++ P I AP F + PP P Sbjct: 434 SSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGP 471 >gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sapiens] Length = 2603 Score = 64.3 bits (155), Expect = 7e-10 Identities = 81/337 (24%), Positives = 121/337 (35%), Gaps = 34/337 (10%) Query: 652 VSLVPPAFPVSMPVPPPGFSPIPPPPFLRA-----SFNPSQPPP------GFMPPPVPPP 700 V+ V P FPVS+P+ PPP F A +F +PP G PP Sbjct: 1870 VNNVRPGFPVSLPL------AYPPPQFAHALLAAQTFQQIRPPRLPMTHFGGTFPPAQST 1923 Query: 701 VVPPPTIPPVVPTSLVQPSLSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAP 760 P P P + P M P GS V GS+ S+ T+ + + Sbjct: 1924 WGPFPVRPLSPARATNSPKPHMVPRHSNQNSSGSQVNSAGSLTSSPTTTTSSSASTVPGT 1983 Query: 761 TKQAEPEEKVPHLIDHQISSGENTRSVIPNDISSNAAILGGQPPNVTSNSGILGVQRPNV 820 + P P + + T + +++ A+ P N T P Sbjct: 1984 STNGSPSS--PSVRRQLFVTVVKTSNATTTTVTTTASNNNTAPTNATYPMPTAKEHYPVS 2041 Query: 821 SSNSEILGVRPSNVSSSSGII--AAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPN 878 S +S +P VS +S + +A P + ++S PP V ++ PPN + Sbjct: 2042 SPSSPSPPAQPGGVSRNSPLDCGSASPNKVASSSEQEAGSPPVVETTN----TRPPNSSS 2097 Query: 879 NSGLVGVQPPNVPNTPGLLGTQ--PPAGPQNLPPLSIPNQRMPTMPM-LDIRPGLIPQAP 935 +SG N PG + + PP +PP P RM P+ P +P Sbjct: 2098 SSGSSSAH-SNQQQPPGSVSQEPRPPLQQSQVPP---PEVRMTVPPLATSSAPVAVPSTA 2153 Query: 936 GPRFPLIQPGIPPQRGIPPPSVLDSALHPPPRGPFPP 972 +P+ P P P P + A+ PPP G P Sbjct: 2154 PVTYPM--PQTPMGCPQPTPKMETPAIRPPPHGTTAP 2188 Score = 40.0 bits (92), Expect = 0.014 Identities = 92/366 (25%), Positives = 130/366 (35%), Gaps = 73/366 (19%) Query: 593 ETVNTEWETVKSSEPVKETVQTTQSPT-PVEKETVVTTQAEVFPPPVAMLQIPVAPAVPT 651 ET NT SS Q P V +E Q PPP + +P Sbjct: 2086 ETTNTRPPNSSSSSGSSSAHSNQQQPPGSVSQEPRPPLQQSQVPPPEVRMTVPPLATSSA 2145 Query: 652 VSLVPPAFPVSMPVP-PPGFSPIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPPPTI--- 707 VP PV+ P+P P P P P + P PP G P V ++ Sbjct: 2146 PVAVPSTAPVTYPMPQTPMGCPQPTPKMETPAIRP--PPHGTTAPHKNSASVQNSSVAVL 2203 Query: 708 -------PPVVPTSLVQPSLSMTPETVKDVGFGSLVIPGGSVASNLATSALPAG---NVF 757 P VP+S+ PS T + + V P + ++ LP G +F Sbjct: 2204 SVNHIKRPHSVPSSVQLPSTLSTQSACQ-----NSVHPANKPIAPNFSAPLPFGPFSTLF 2258 Query: 758 -NAPT------------KQAEPEEKVPHLIDHQISSGENTRSVIPND----ISSNAAILG 800 N+PT Q+ PE + SG++ S +PN S + G Sbjct: 2259 ENSPTSAHAFWGGSVVSSQSTPESML---------SGKS--SYLPNSDPLHQSDTSKAPG 2307 Query: 801 GQPP---NVTSNSGILGVQRP--NVSSNSEILGVRPSNVSSS---------SGIIAAQPP 846 +PP S SGI+ + P +V+ +S LG SN+S G AA Sbjct: 2308 FRPPLQRPAPSPSGIVNMDSPYGSVTPSSTHLGNFASNISGGQMYGPGAPLGGAPAAANF 2367 Query: 847 NILNNSGILGIQP-PSVSNSSGLLGV-----LPPNIPNNSGLVGVQPPNVP---NTPGLL 897 N + S + + P S SN S V P P++ L +P NV P + Sbjct: 2368 NRQHFSPLSLLTPCSSASNDSSAQSVSSGVRAPSPAPSSVPLGSEKPSNVSQDRKVPVPI 2427 Query: 898 GTQPPA 903 GT+ A Sbjct: 2428 GTERSA 2433 >gi|38683816 ankyrin repeat domain protein 17 isoform b [Homo sapiens] Length = 2352 Score = 64.3 bits (155), Expect = 7e-10 Identities = 81/337 (24%), Positives = 121/337 (35%), Gaps = 34/337 (10%) Query: 652 VSLVPPAFPVSMPVPPPGFSPIPPPPFLRA-----SFNPSQPPP------GFMPPPVPPP 700 V+ V P FPVS+P+ PPP F A +F +PP G PP Sbjct: 1619 VNNVRPGFPVSLPL------AYPPPQFAHALLAAQTFQQIRPPRLPMTHFGGTFPPAQST 1672 Query: 701 VVPPPTIPPVVPTSLVQPSLSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAP 760 P P P + P M P GS V GS+ S+ T+ + + Sbjct: 1673 WGPFPVRPLSPARATNSPKPHMVPRHSNQNSSGSQVNSAGSLTSSPTTTTSSSASTVPGT 1732 Query: 761 TKQAEPEEKVPHLIDHQISSGENTRSVIPNDISSNAAILGGQPPNVTSNSGILGVQRPNV 820 + P P + + T + +++ A+ P N T P Sbjct: 1733 STNGSPSS--PSVRRQLFVTVVKTSNATTTTVTTTASNNNTAPTNATYPMPTAKEHYPVS 1790 Query: 821 SSNSEILGVRPSNVSSSSGII--AAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPN 878 S +S +P VS +S + +A P + ++S PP V ++ PPN + Sbjct: 1791 SPSSPSPPAQPGGVSRNSPLDCGSASPNKVASSSEQEAGSPPVVETTN----TRPPNSSS 1846 Query: 879 NSGLVGVQPPNVPNTPGLLGTQ--PPAGPQNLPPLSIPNQRMPTMPM-LDIRPGLIPQAP 935 +SG N PG + + PP +PP P RM P+ P +P Sbjct: 1847 SSGSSSAH-SNQQQPPGSVSQEPRPPLQQSQVPP---PEVRMTVPPLATSSAPVAVPSTA 1902 Query: 936 GPRFPLIQPGIPPQRGIPPPSVLDSALHPPPRGPFPP 972 +P+ P P P P + A+ PPP G P Sbjct: 1903 PVTYPM--PQTPMGCPQPTPKMETPAIRPPPHGTTAP 1937 Score = 40.0 bits (92), Expect = 0.014 Identities = 92/366 (25%), Positives = 130/366 (35%), Gaps = 73/366 (19%) Query: 593 ETVNTEWETVKSSEPVKETVQTTQSPT-PVEKETVVTTQAEVFPPPVAMLQIPVAPAVPT 651 ET NT SS Q P V +E Q PPP + +P Sbjct: 1835 ETTNTRPPNSSSSSGSSSAHSNQQQPPGSVSQEPRPPLQQSQVPPPEVRMTVPPLATSSA 1894 Query: 652 VSLVPPAFPVSMPVP-PPGFSPIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPPPTI--- 707 VP PV+ P+P P P P P + P PP G P V ++ Sbjct: 1895 PVAVPSTAPVTYPMPQTPMGCPQPTPKMETPAIRP--PPHGTTAPHKNSASVQNSSVAVL 1952 Query: 708 -------PPVVPTSLVQPSLSMTPETVKDVGFGSLVIPGGSVASNLATSALPAG---NVF 757 P VP+S+ PS T + + V P + ++ LP G +F Sbjct: 1953 SVNHIKRPHSVPSSVQLPSTLSTQSACQ-----NSVHPANKPIAPNFSAPLPFGPFSTLF 2007 Query: 758 -NAPT------------KQAEPEEKVPHLIDHQISSGENTRSVIPND----ISSNAAILG 800 N+PT Q+ PE + SG++ S +PN S + G Sbjct: 2008 ENSPTSAHAFWGGSVVSSQSTPESML---------SGKS--SYLPNSDPLHQSDTSKAPG 2056 Query: 801 GQPP---NVTSNSGILGVQRP--NVSSNSEILGVRPSNVSSS---------SGIIAAQPP 846 +PP S SGI+ + P +V+ +S LG SN+S G AA Sbjct: 2057 FRPPLQRPAPSPSGIVNMDSPYGSVTPSSTHLGNFASNISGGQMYGPGAPLGGAPAAANF 2116 Query: 847 NILNNSGILGIQP-PSVSNSSGLLGV-----LPPNIPNNSGLVGVQPPNVP---NTPGLL 897 N + S + + P S SN S V P P++ L +P NV P + Sbjct: 2117 NRQHFSPLSLLTPCSSASNDSSAQSVSSGVRAPSPAPSSVPLGSEKPSNVSQDRKVPVPI 2176 Query: 898 GTQPPA 903 GT+ A Sbjct: 2177 GTERSA 2182 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.313 0.133 0.395 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 62,261,022 Number of Sequences: 37866 Number of extensions: 4022400 Number of successful extensions: 58814 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 678 Number of HSP's successfully gapped in prelim test: 1398 Number of HSP's that attempted gapping in prelim test: 19871 Number of HSP's gapped (non-prelim): 17675 length of query: 1271 length of database: 18,247,518 effective HSP length: 114 effective length of query: 1157 effective length of database: 13,930,794 effective search space: 16117928658 effective search space used: 16117928658 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.