Guide to the Human Genome
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Search of human proteins with 62460633

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|62460633 RNA-binding motif protein 16 [Homo sapiens]
         (1271 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|62460633 RNA-binding motif protein 16 [Homo sapiens]              2580   0.0  
gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1 [...   682   0.0  
gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 ...   671   0.0  
gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2 ...   648   0.0  
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    88   6e-17
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]       80   1e-14
gi|47132519 Ras association and pleckstrin homology domains 1 is...    77   8e-14
gi|160707881 formin 2 [Homo sapiens]                                   72   3e-12
gi|16554449 zonadhesin isoform 3 [Homo sapiens]                        72   4e-12
gi|27881494 zonadhesin isoform 6 [Homo sapiens]                        72   4e-12
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    70   2e-11
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    70   2e-11
gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo s...    70   2e-11
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s...    70   2e-11
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]     69   2e-11
gi|14670268 RD RNA-binding protein [Homo sapiens]                      69   3e-11
gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens]                    69   4e-11
gi|24307919 small nuclear ribonucleoprotein 27kDa (U4/U6.U5) [Ho...    67   8e-11
gi|146134388 YLP motif containing 1 [Homo sapiens]                     67   8e-11
gi|4508017 zinc finger protein 207 isoform a [Homo sapiens]            67   1e-10
gi|9558733 transformer-2 alpha [Homo sapiens]                          67   1e-10
gi|4759098 splicing factor, arginine/serine-rich 10 [Homo sapiens]     67   1e-10
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]         66   2e-10
gi|33620745 pre-mRNA cleavage complex II protein Pcf11 [Homo sap...    66   2e-10
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    65   4e-10
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    65   4e-10
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ...    65   5e-10
gi|163965366 nascent polypeptide-associated complex alpha subuni...    64   7e-10
gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sap...    64   7e-10
gi|38683816 ankyrin repeat domain protein 17 isoform b [Homo sap...    64   7e-10

>gi|62460633 RNA-binding motif protein 16 [Homo sapiens]
          Length = 1271

 Score = 2580 bits (6688), Expect = 0.0
 Identities = 1271/1271 (100%), Positives = 1271/1271 (100%)

Query: 1    MEAVKTFNSELYSLNDYKPPISKAKMTQITKAAIKAIKFYKHVVQSVEKFIQKCKPEYKV 60
            MEAVKTFNSELYSLNDYKPPISKAKMTQITKAAIKAIKFYKHVVQSVEKFIQKCKPEYKV
Sbjct: 1    MEAVKTFNSELYSLNDYKPPISKAKMTQITKAAIKAIKFYKHVVQSVEKFIQKCKPEYKV 60

Query: 61   PGLYVIDSIVRQSRHQFGQEKDVFAPRFSNNIISTFQNLYRCPGDDKSKIVRVLNLWQKN 120
            PGLYVIDSIVRQSRHQFGQEKDVFAPRFSNNIISTFQNLYRCPGDDKSKIVRVLNLWQKN
Sbjct: 61   PGLYVIDSIVRQSRHQFGQEKDVFAPRFSNNIISTFQNLYRCPGDDKSKIVRVLNLWQKN 120

Query: 121  NVFKSEIIQPLLDMAAGIPPPVVTPVLASTTTAMSNTPGTPVTPVTPANVVQGLPDPWVS 180
            NVFKSEIIQPLLDMAAGIPPPVVTPVLASTTTAMSNTPGTPVTPVTPANVVQGLPDPWVS
Sbjct: 121  NVFKSEIIQPLLDMAAGIPPPVVTPVLASTTTAMSNTPGTPVTPVTPANVVQGLPDPWVS 180

Query: 181  QITNTDTLAAVAQILQSPQGQQLQQLIQTLQIQQQKPQPSILQALDAGLVVQLQALTAQL 240
            QITNTDTLAAVAQILQSPQGQQLQQLIQTLQIQQQKPQPSILQALDAGLVVQLQALTAQL
Sbjct: 181  QITNTDTLAAVAQILQSPQGQQLQQLIQTLQIQQQKPQPSILQALDAGLVVQLQALTAQL 240

Query: 241  TAAAAAANTLTPLEQGVSFNKKLMDRFDFGEDSEHSEEPKKEIPASQLSHVSESVNNSIF 300
            TAAAAAANTLTPLEQGVSFNKKLMDRFDFGEDSEHSEEPKKEIPASQLSHVSESVNNSIF
Sbjct: 241  TAAAAAANTLTPLEQGVSFNKKLMDRFDFGEDSEHSEEPKKEIPASQLSHVSESVNNSIF 300

Query: 301  HQIAEQLQQQNLEHLRQQLLEQQQPQKATPQDSQEGTFGSEHSASPSQGSSQQHFLEPEV 360
            HQIAEQLQQQNLEHLRQQLLEQQQPQKATPQDSQEGTFGSEHSASPSQGSSQQHFLEPEV
Sbjct: 301  HQIAEQLQQQNLEHLRQQLLEQQQPQKATPQDSQEGTFGSEHSASPSQGSSQQHFLEPEV 360

Query: 361  NLDDSIDIQQQDMDIDEGQDGVEEEVFEQEAKKVAVRSRSRTHSRSRSRSPRKRRSRSRS 420
            NLDDSIDIQQQDMDIDEGQDGVEEEVFEQEAKKVAVRSRSRTHSRSRSRSPRKRRSRSRS
Sbjct: 361  NLDDSIDIQQQDMDIDEGQDGVEEEVFEQEAKKVAVRSRSRTHSRSRSRSPRKRRSRSRS 420

Query: 421  GSRKRKHRKRSRSRSRERKRKSSRSYSSERRAREREKERQKKGLPPIRSKTLSVCSTTLW 480
            GSRKRKHRKRSRSRSRERKRKSSRSYSSERRAREREKERQKKGLPPIRSKTLSVCSTTLW
Sbjct: 421  GSRKRKHRKRSRSRSRERKRKSSRSYSSERRAREREKERQKKGLPPIRSKTLSVCSTTLW 480

Query: 481  VGQVDKKATQQDLTNLFEEFGQIESINMIPPRGCAYVCMVHRQDAFRALQKLSSGSYKIG 540
            VGQVDKKATQQDLTNLFEEFGQIESINMIPPRGCAYVCMVHRQDAFRALQKLSSGSYKIG
Sbjct: 481  VGQVDKKATQQDLTNLFEEFGQIESINMIPPRGCAYVCMVHRQDAFRALQKLSSGSYKIG 540

Query: 541  SKVIKIAWALNKGVKTEYKQFWDVDLGVTYIPWEKVKVDDLEGFAEGGMIDQETVNTEWE 600
            SKVIKIAWALNKGVKTEYKQFWDVDLGVTYIPWEKVKVDDLEGFAEGGMIDQETVNTEWE
Sbjct: 541  SKVIKIAWALNKGVKTEYKQFWDVDLGVTYIPWEKVKVDDLEGFAEGGMIDQETVNTEWE 600

Query: 601  TVKSSEPVKETVQTTQSPTPVEKETVVTTQAEVFPPPVAMLQIPVAPAVPTVSLVPPAFP 660
            TVKSSEPVKETVQTTQSPTPVEKETVVTTQAEVFPPPVAMLQIPVAPAVPTVSLVPPAFP
Sbjct: 601  TVKSSEPVKETVQTTQSPTPVEKETVVTTQAEVFPPPVAMLQIPVAPAVPTVSLVPPAFP 660

Query: 661  VSMPVPPPGFSPIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPPPTIPPVVPTSLVQPSL 720
            VSMPVPPPGFSPIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPPPTIPPVVPTSLVQPSL
Sbjct: 661  VSMPVPPPGFSPIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPPPTIPPVVPTSLVQPSL 720

Query: 721  SMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDHQISS 780
            SMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDHQISS
Sbjct: 721  SMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDHQISS 780

Query: 781  GENTRSVIPNDISSNAAILGGQPPNVTSNSGILGVQRPNVSSNSEILGVRPSNVSSSSGI 840
            GENTRSVIPNDISSNAAILGGQPPNVTSNSGILGVQRPNVSSNSEILGVRPSNVSSSSGI
Sbjct: 781  GENTRSVIPNDISSNAAILGGQPPNVTSNSGILGVQRPNVSSNSEILGVRPSNVSSSSGI 840

Query: 841  IAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGLLGTQ 900
            IAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGLLGTQ
Sbjct: 841  IAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGLLGTQ 900

Query: 901  PPAGPQNLPPLSIPNQRMPTMPMLDIRPGLIPQAPGPRFPLIQPGIPPQRGIPPPSVLDS 960
            PPAGPQNLPPLSIPNQRMPTMPMLDIRPGLIPQAPGPRFPLIQPGIPPQRGIPPPSVLDS
Sbjct: 901  PPAGPQNLPPLSIPNQRMPTMPMLDIRPGLIPQAPGPRFPLIQPGIPPQRGIPPPSVLDS 960

Query: 961  ALHPPPRGPFPPGDIFSQPERPFLAPGRQSVDNVTNPEKRIPLGNDNIQQEGDRDYRFPP 1020
            ALHPPPRGPFPPGDIFSQPERPFLAPGRQSVDNVTNPEKRIPLGNDNIQQEGDRDYRFPP
Sbjct: 961  ALHPPPRGPFPPGDIFSQPERPFLAPGRQSVDNVTNPEKRIPLGNDNIQQEGDRDYRFPP 1020

Query: 1021 IETRESISRPPPVDVRDVVGRPIDPREGPGRPPLDGRDHFGRPPVDIRENLVRPGIDHLG 1080
            IETRESISRPPPVDVRDVVGRPIDPREGPGRPPLDGRDHFGRPPVDIRENLVRPGIDHLG
Sbjct: 1021 IETRESISRPPPVDVRDVVGRPIDPREGPGRPPLDGRDHFGRPPVDIRENLVRPGIDHLG 1080

Query: 1081 RRDHFGFNPEKPWGHRGDFDEREHRVLPVYGGPKGLHEERGRFRSGNYRFDPRSGPWNRG 1140
            RRDHFGFNPEKPWGHRGDFDEREHRVLPVYGGPKGLHEERGRFRSGNYRFDPRSGPWNRG
Sbjct: 1081 RRDHFGFNPEKPWGHRGDFDEREHRVLPVYGGPKGLHEERGRFRSGNYRFDPRSGPWNRG 1140

Query: 1141 FGQEVHRDFDDRRRPWERQRDRDDRDFDFCREMNGNRLGRDRIQNTWVPPPHARVFDYFE 1200
            FGQEVHRDFDDRRRPWERQRDRDDRDFDFCREMNGNRLGRDRIQNTWVPPPHARVFDYFE
Sbjct: 1141 FGQEVHRDFDDRRRPWERQRDRDDRDFDFCREMNGNRLGRDRIQNTWVPPPHARVFDYFE 1200

Query: 1201 GATSQRKGDNVPQVNGENTERHAQPPPIPVQNDPELYEKLTSSNEINKEKSDTVADIESE 1260
            GATSQRKGDNVPQVNGENTERHAQPPPIPVQNDPELYEKLTSSNEINKEKSDTVADIESE
Sbjct: 1201 GATSQRKGDNVPQVNGENTERHAQPPPIPVQNDPELYEKLTSSNEINKEKSDTVADIESE 1260

Query: 1261 PVVESTETEGT 1271
            PVVESTETEGT
Sbjct: 1261 PVVESTETEGT 1271


>gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1 [Homo
            sapiens]
          Length = 1147

 Score =  682 bits (1759), Expect = 0.0
 Identities = 495/1278 (38%), Positives = 653/1278 (51%), Gaps = 261/1278 (20%)

Query: 1    MEAVKTFNSELYSLNDYKPPISKAKMTQITKAAIKAIKFYKHVVQSVEKFIQKCKPEYKV 60
            M+AV  FN EL+SL D KPPIS+AKM  ITKAAIKAIK YKHVVQ VEKFI+KCKPEYKV
Sbjct: 1    MDAVNAFNQELFSLMDMKPPISRAKMILITKAAIKAIKLYKHVVQIVEKFIKKCKPEYKV 60

Query: 61   PGLYVIDSIVRQSRHQFGQEKDVFAPRFSNNIISTFQNLYRCPGDDKSKIVRVLNLWQKN 120
            PGLYVIDSIVRQSRHQFG +KDVF PRFS NI +TFQ LY CP +DKSKIVRVLNLWQKN
Sbjct: 61   PGLYVIDSIVRQSRHQFGTDKDVFGPRFSKNITATFQYLYLCPSEDKSKIVRVLNLWQKN 120

Query: 121  NVFKSEIIQPLLDMAAGIPPPVVTPVLASTTTAMSNTPGTPVTPVTPANV--VQGLPD-- 176
             VFK EIIQPLLDMAAG      T   A     ++N  G+P  PV  ++    Q  P+  
Sbjct: 121  GVFKIEIIQPLLDMAAG------TSNAAPVAENVTNNEGSPPPPVKVSSEPPTQATPNSV 174

Query: 177  PWVSQITNTDTLAAVAQILQSPQGQQLQQLIQTLQIQQQKPQPSILQALDAGLVVQLQAL 236
            P V Q+ ++D  AAVAQ+ Q+ QGQQLQQ++QT Q Q  KPQ     ALD  ++ Q+QA+
Sbjct: 175  PAVPQLPSSDAFAAVAQLFQTTQGQQLQQILQTFQ-QPPKPQSP---ALDNAVMAQVQAI 230

Query: 237  TAQL----TAAAAAANTLTPLEQGVSFNKKLMDRFDFGEDSEHSEEPKKE---------- 282
            TAQL    T  +       P EQ  +F+KKL+DRFD+ ++ E  EE KKE          
Sbjct: 231  TAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAP 290

Query: 283  -----------IPASQL-SHVSESVNNSIFHQIAEQLQQ------QNLEHLRQQLLEQQQ 324
                       +PA+   +  S     + F    + +QQ      QN++  + +++  QQ
Sbjct: 291  AAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQ 350

Query: 325  P----QKATPQDSQEGTFGSEHSASPSQGSSQQHFLEPE--VNLDDSIDIQQQDMDIDEG 378
                 Q   P + Q   FG     +P      Q  + P   V        Q Q+  + + 
Sbjct: 351  DPMHHQVPLPPNGQMPGFGL--LPTPPFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQK 408

Query: 379  QDGVEEEVFE---QEAKKVAVRSRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRKRSRSRS 435
                E EV +   QE K+    +R ++ SRS SRSP++RRSRS S SR+ +HR RSRSRS
Sbjct: 409  PHQQEMEVEQPCIQEVKRHMSDNR-KSRSRSASRSPKRRRSRSGSRSRRSRHR-RSRSRS 466

Query: 436  RERKRKSSRSYSSERRAREREKERQKKGLPPIRSKTLSVCSTTLWVGQVDKKATQQDLTN 495
            R+R+R S RS S ERR RE+E+ER++KGLP ++ +T SVCSTTLWVGQ+DK+ TQQD+ +
Sbjct: 467  RDRRRHSPRSRSQERRDREKERERRQKGLPQVKPETASVCSTTLWVGQLDKRTTQQDVAS 526

Query: 496  LFEEFGQIESINMIPPRGCAYVCMVHRQDAFRALQKLSSGSYKIGSKVIKIAWALNKGVK 555
            L EEFG IESINMIPPRGCAY+ MVHRQDA+RALQKLS G+YK+  K IKIAWALNKG+K
Sbjct: 527  LLEEFGPIESINMIPPRGCAYIVMVHRQDAYRALQKLSRGNYKVNQKSIKIAWALNKGIK 586

Query: 556  TEYKQFWDVDLGVTYIPWEKVKVDDLEGFAEGGMIDQETVNTEWETVKSSEPVKETVQT- 614
             +YKQ+WDV+LGVTYIPW+KVK ++LE F EGGM+D +T+N +W+ +   +P  E  Q  
Sbjct: 587  ADYKQYWDVELGVTYIPWDKVKPEELESFCEGGMLDSDTLNPDWKGI-PKKPENEVAQNG 645

Query: 615  ------TQSPTPVEKETVVTTQAEVFPPPVAM--LQIPV-APAVPTV-SLVPPAFPVSMP 664
                  T+  +P+ K   V       P P+ +   Q+P   P  P V +L PPAF   + 
Sbjct: 646  GAETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLG 705

Query: 665  VPPPGFS-----PIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPPPTIPP--VVPTSLVQ 717
            +PPPGF      P PPPPFLR  FNP   PPGF+PP  PPP+ PP +IPP    P S+  
Sbjct: 706  IPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPN 765

Query: 718  PSLS-MTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDH 776
             +++ +  +T KD+  G+                 P   V +     AE  + V      
Sbjct: 766  STIAGINEDTTKDLSIGN-----------------PIPTVVSGARGNAESGDSV------ 802

Query: 777  QISSGENTRSVIPNDISSNAAILGGQPPNVTSNSGILGVQRPNVSSNSEILGVRPSNVSS 836
                 +   S +P    +N        P VT    +LG Q           GV P  V  
Sbjct: 803  -----KMYGSAVPPAAPTNL-----PTPPVTQPVSLLGTQ-----------GVAPGPV-- 839

Query: 837  SSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGL 896
                              +G+Q P    S+GLLG                       PGL
Sbjct: 840  ------------------IGLQAP----STGLLGA---------------------RPGL 856

Query: 897  LGTQPPAGPQNLPPLSIPNQRMPTMPMLDIRPGLIPQAPGPRFPLIQPGIPPQRGIPPPS 956
            +  Q P G   +PP  +  QR P MP   + P ++ + P P         P    +PPP 
Sbjct: 857  IPLQRPPG---MPPPHL--QRFPLMPPRPMPPHMMHRGPPPG--------PGGFAMPPPH 903

Query: 957  VLDSALHPPPRGPFPPGDIFSQPERPFLAPGRQSVDNVTNPEKRIPLGNDNIQQEGDRDY 1016
             +        +GPFP       P  PF+ PG         P    P   D  QQ   +  
Sbjct: 904  GM--------KGPFP-------PHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQ 948

Query: 1017 RFPPIET-----RESISRPPPVDVRDVVGRPIDPREGPGRPPLDGRDHF--GRPPVDIRE 1069
            + P  +      ++   +PPP        +P   ++ P +   D R  F  GR       
Sbjct: 949  QQPQPQAPQQPQQQQQQQPPPSQ------QPPPTQQQPQQFRNDNRQQFNSGRDQ----- 997

Query: 1070 NLVRPGIDHLGRRDHFG---FNPEKPWGHRGDFDEREHRVLPVYGGPKGLHEERGRFRSG 1126
                   +  GRR  FG    N  + +G+R D  +  +R    +G               
Sbjct: 998  -------ERFGRRS-FGNRVENDRERYGNRNDDRDNSNRDRREWG--------------- 1034

Query: 1127 NYRFDPRSGPWNRGFGQEVHRDFDDRRR--PWERQRDRDDRDFDFCREMNGNRLGRDRIQ 1184
                        R   ++ HRD ++R R     R R+RD RD +  RE    R G+++ +
Sbjct: 1035 -----------RRSPDRDRHRDLEERNRRSSGHRDRERDSRDRESRREKEEAR-GKEKPE 1082

Query: 1185 -------NTWVPPPHARV 1195
                   N  V PP ++V
Sbjct: 1083 VTDRAGGNKTVEPPISQV 1100



 Score = 39.7 bits (91), Expect = 0.019
 Identities = 47/201 (23%), Positives = 77/201 (38%), Gaps = 20/201 (9%)

Query: 322  QQQPQKATPQDSQEGTFGSEHSASPSQGS--SQQHFLEPEVNLDDSIDIQQQDMDIDEGQ 379
            QQQPQ   PQ  Q+     +    PSQ    +QQ   +P+   +D+    +Q  +    Q
Sbjct: 948  QQQPQPQAPQQPQQQ---QQQQPPPSQQPPPTQQ---QPQQFRNDN----RQQFNSGRDQ 997

Query: 380  DGVEEEVFEQEAKKVAVRSRSRTHSRSRSRSPRK---RRSRSRSGSRKRKHRKRSRSRSR 436
            +      F    +    R  +R   R  S   R+   RRS  R   R  + R R  S  R
Sbjct: 998  ERFGRRSFGNRVENDRERYGNRNDDRDNSNRDRREWGRRSPDRDRHRDLEERNRRSSGHR 1057

Query: 437  ERKRKSSRSYSSERRAREREKERQKKGLPPIRSKTLSVCSTTLWVGQVDKKATQQDLTNL 496
            +R+R      S +R +R  ++E + K  P +  +     +    + QV    T  +L   
Sbjct: 1058 DRERD-----SRDRESRREKEEARGKEKPEVTDRAGGNKTVEPPISQVGNVDTASELEKG 1112

Query: 497  FEEFGQIESINMIPPRGCAYV 517
              E   ++    +P    + V
Sbjct: 1113 VSEAAVLKPSEELPAEATSSV 1133


>gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 [Homo
            sapiens]
          Length = 1125

 Score =  671 bits (1731), Expect = 0.0
 Identities = 459/1098 (41%), Positives = 591/1098 (53%), Gaps = 189/1098 (17%)

Query: 1    MEAVKTFNSELYSLNDYKPPISKAKMTQITKAAIKAIKFYKHVVQSVEKFIQKCKPEYKV 60
            M+AV  FN EL+SL D KPPIS+AKM  ITKAAIKAIK YKHVVQ VEKFI+KCKPEYKV
Sbjct: 1    MDAVNAFNQELFSLMDMKPPISRAKMILITKAAIKAIKLYKHVVQIVEKFIKKCKPEYKV 60

Query: 61   PGLYVIDSIVRQSRHQFGQEKDVFAPRFSNNIISTFQNLYRCPGDDKSKIVRVLNLWQKN 120
            PGLYVIDSIVRQSRHQFG +KDVF PRFS NI +TFQ LY CP +DKSKIVRVLNLWQKN
Sbjct: 61   PGLYVIDSIVRQSRHQFGTDKDVFGPRFSKNITATFQYLYLCPSEDKSKIVRVLNLWQKN 120

Query: 121  NVFKSEIIQPLLDMAAGIPPPVVTPVLASTTTAMSNTPGTPVTPVTPANV--VQGLPD-- 176
             VFK EIIQPLLDMAAG      T   A     ++N  G+P  PV  ++    Q  P+  
Sbjct: 121  GVFKIEIIQPLLDMAAG------TSNAAPVAENVTNNEGSPPPPVKVSSEPPTQATPNSV 174

Query: 177  PWVSQITNTDTLAAVAQILQSPQGQQLQQLIQTLQIQQQKPQPSILQALDAGLVVQLQAL 236
            P V Q+ ++D  AAVAQ+ Q+ QGQQLQQ++QT Q Q  KPQ     ALD  ++ Q+QA+
Sbjct: 175  PAVPQLPSSDAFAAVAQLFQTTQGQQLQQILQTFQ-QPPKPQSP---ALDNAVMAQVQAI 230

Query: 237  TAQL----TAAAAAANTLTPLEQGVSFNKKLMDRFDFGEDSEHSEEPKKE---------- 282
            TAQL    T  +       P EQ  +F+KKL+DRFD+ ++ E  EE KKE          
Sbjct: 231  TAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAP 290

Query: 283  -----------IPASQL-SHVSESVNNSIFHQIAEQLQQ------QNLEHLRQQLLEQQQ 324
                       +PA+   +  S     + F    + +QQ      QN++  + +++  QQ
Sbjct: 291  AAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQ 350

Query: 325  P----QKATPQDSQEGTFGSEHSASPSQGSSQQHFLEPE--VNLDDSIDIQQQDMDIDEG 378
                 Q   P + Q   FG     +P      Q  + P   V        Q Q+  + + 
Sbjct: 351  DPMHHQVPLPPNGQMPGFGL--LPTPPFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQK 408

Query: 379  QDGVEEEVFE---QEAKKVAVRSRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRKRSRSRS 435
                E EV +   QE K+    +R ++ SRS SRSP++RRSRS S SR+ +HR RSRSRS
Sbjct: 409  PHQQEMEVEQPCIQEVKRHMSDNR-KSRSRSASRSPKRRRSRSGSRSRRSRHR-RSRSRS 466

Query: 436  RERKRKSSRSYSSERRAREREKERQKKGLPPIRSKTLSVCSTTLWVGQVDKKATQQDLTN 495
            R+R+R S RS S ERR RE+E+ER++KGLP ++ +T SVCSTTLWVGQ+DK+ TQQD+ +
Sbjct: 467  RDRRRHSPRSRSQERRDREKERERRQKGLPQVKPETASVCSTTLWVGQLDKRTTQQDVAS 526

Query: 496  LFEEFGQIESINMIPPRGCAYVCMVHRQDAFRALQKLSSGSYKIGSKVIKIAWALNKGVK 555
            L EEFG IESINMIPPRGCAY+ MVHRQDA+RALQKLS G+YK+  K IKIAWALNKG+K
Sbjct: 527  LLEEFGPIESINMIPPRGCAYIVMVHRQDAYRALQKLSRGNYKVNQKSIKIAWALNKGIK 586

Query: 556  TEYKQFWDVDLGVTYIPWEKVKVDDLEGFAEGGMIDQETVNTEWETVKSSEPVKETVQT- 614
             +YKQ+WDV+LGVTYIPW+KVK ++LE F EGGM+D +T+N +W+ +   +P  E  Q  
Sbjct: 587  ADYKQYWDVELGVTYIPWDKVKPEELESFCEGGMLDSDTLNPDWKGI-PKKPENEVAQNG 645

Query: 615  ------TQSPTPVEKETVVTTQAEVFPPPVAM--LQIPV-APAVPTV-SLVPPAFPVSMP 664
                  T+  +P+ K   V       P P+ +   Q+P   P  P V +L PPAF   + 
Sbjct: 646  GAETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLG 705

Query: 665  VPPPGFS-----PIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPPPTIPPVVPTSLVQPS 719
            +PPPGF      P PPPPFLR  FNP   PPGF+PP  PPP+ PP +IPP     +  P+
Sbjct: 706  IPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPN 765

Query: 720  LSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDHQIS 779
            L          G       G SV   +  SA+P     N PT                  
Sbjct: 766  LVS--------GARGNAESGDSV--KMYGSAVPPAAPTNLPT------------------ 797

Query: 780  SGENTRSVIPNDISSNAAILGGQPPNVTSNSGILGVQRPNVSSNSEILGVRPSNV----S 835
                                    P VT    +LG Q           GV P  V    +
Sbjct: 798  ------------------------PPVTQPVSLLGTQ-----------GVAPGPVIGLQA 822

Query: 836  SSSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPG 895
             S+G++ A+P       G++ +Q P         G+ PP++        + PP  P  P 
Sbjct: 823  PSTGLLGARP-------GLIPLQRPP--------GMPPPHLQR----FPLMPPR-PMPPH 862

Query: 896  LLGTQPPAGPQNL---PPLSIPNQRMPTMPMLDIRPGLIPQAPGP-------------RF 939
            ++   PP GP      PP  +     P  P   +RPG +P   GP             + 
Sbjct: 863  MMHRGPPPGPGGFAMPPPHGMKGPFPPHGPF--VRPGGMPGLGGPGPGPGGPEDRDGRQQ 920

Query: 940  PLIQPGIPPQRGIPPPSVLDSALHPPPRGPFPPGDIFSQPERPFLAPGRQSVDNVTNPEK 999
            P  QP   PQ   P          PPP    PP     QP++ F    RQ  ++  + E+
Sbjct: 921  PPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQ--QQPQQ-FRNDNRQQFNSGRDQER 977

Query: 1000 --RIPLGNDNIQQEGDRD 1015
              R   GN   + E DR+
Sbjct: 978  FGRRSFGN---RVENDRE 992



 Score = 39.7 bits (91), Expect = 0.019
 Identities = 47/201 (23%), Positives = 77/201 (38%), Gaps = 20/201 (9%)

Query: 322  QQQPQKATPQDSQEGTFGSEHSASPSQGS--SQQHFLEPEVNLDDSIDIQQQDMDIDEGQ 379
            QQQPQ   PQ  Q+     +    PSQ    +QQ   +P+   +D+    +Q  +    Q
Sbjct: 926  QQQPQPQAPQQPQQQ---QQQQPPPSQQPPPTQQ---QPQQFRNDN----RQQFNSGRDQ 975

Query: 380  DGVEEEVFEQEAKKVAVRSRSRTHSRSRSRSPRK---RRSRSRSGSRKRKHRKRSRSRSR 436
            +      F    +    R  +R   R  S   R+   RRS  R   R  + R R  S  R
Sbjct: 976  ERFGRRSFGNRVENDRERYGNRNDDRDNSNRDRREWGRRSPDRDRHRDLEERNRRSSGHR 1035

Query: 437  ERKRKSSRSYSSERRAREREKERQKKGLPPIRSKTLSVCSTTLWVGQVDKKATQQDLTNL 496
            +R+R      S +R +R  ++E + K  P +  +     +    + QV    T  +L   
Sbjct: 1036 DRERD-----SRDRESRREKEEARGKEKPEVTDRAGGNKTVEPPISQVGNVDTASELEKG 1090

Query: 497  FEEFGQIESINMIPPRGCAYV 517
              E   ++    +P    + V
Sbjct: 1091 VSEAAVLKPSEELPAEATSSV 1111


>gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2 [Homo
            sapiens]
          Length = 1132

 Score =  648 bits (1672), Expect = 0.0
 Identities = 483/1278 (37%), Positives = 640/1278 (50%), Gaps = 276/1278 (21%)

Query: 1    MEAVKTFNSELYSLNDYKPPISKAKMTQITKAAIKAIKFYKHVVQSVEKFIQKCKPEYKV 60
            M+AV  FN EL+SL D KPPIS+AKM  ITKAAIKAIK               CKPEYKV
Sbjct: 1    MDAVNAFNQELFSLMDMKPPISRAKMILITKAAIKAIK---------------CKPEYKV 45

Query: 61   PGLYVIDSIVRQSRHQFGQEKDVFAPRFSNNIISTFQNLYRCPGDDKSKIVRVLNLWQKN 120
            PGLYVIDSIVRQSRHQFG +KDVF PRFS NI +TFQ LY CP +DKSKIVRVLNLWQKN
Sbjct: 46   PGLYVIDSIVRQSRHQFGTDKDVFGPRFSKNITATFQYLYLCPSEDKSKIVRVLNLWQKN 105

Query: 121  NVFKSEIIQPLLDMAAGIPPPVVTPVLASTTTAMSNTPGTPVTPVTPANV--VQGLPD-- 176
             VFK EIIQPLLDMAAG      T   A     ++N  G+P  PV  ++    Q  P+  
Sbjct: 106  GVFKIEIIQPLLDMAAG------TSNAAPVAENVTNNEGSPPPPVKVSSEPPTQATPNSV 159

Query: 177  PWVSQITNTDTLAAVAQILQSPQGQQLQQLIQTLQIQQQKPQPSILQALDAGLVVQLQAL 236
            P V Q+ ++D  AAVAQ+ Q+ QGQQLQQ++QT Q Q  KPQ     ALD  ++ Q+QA+
Sbjct: 160  PAVPQLPSSDAFAAVAQLFQTTQGQQLQQILQTFQ-QPPKPQSP---ALDNAVMAQVQAI 215

Query: 237  TAQL----TAAAAAANTLTPLEQGVSFNKKLMDRFDFGEDSEHSEEPKKE---------- 282
            TAQL    T  +       P EQ  +F+KKL+DRFD+ ++ E  EE KKE          
Sbjct: 216  TAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAP 275

Query: 283  -----------IPASQL-SHVSESVNNSIFHQIAEQLQQ------QNLEHLRQQLLEQQQ 324
                       +PA+   +  S     + F    + +QQ      QN++  + +++  QQ
Sbjct: 276  AAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQ 335

Query: 325  P----QKATPQDSQEGTFGSEHSASPSQGSSQQHFLEPE--VNLDDSIDIQQQDMDIDEG 378
                 Q   P + Q   FG     +P      Q  + P   V        Q Q+  + + 
Sbjct: 336  DPMHHQVPLPPNGQMPGFGL--LPTPPFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQK 393

Query: 379  QDGVEEEVFE---QEAKKVAVRSRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRKRSRSRS 435
                E EV +   QE K+    +R ++ SRS SRSP++RRSRS S SR+ +HR RSRSRS
Sbjct: 394  PHQQEMEVEQPCIQEVKRHMSDNR-KSRSRSASRSPKRRRSRSGSRSRRSRHR-RSRSRS 451

Query: 436  RERKRKSSRSYSSERRAREREKERQKKGLPPIRSKTLSVCSTTLWVGQVDKKATQQDLTN 495
            R+R+R S RS S ERR RE+E+ER++KGLP ++ +T SVCSTTLWVGQ+DK+ TQQD+ +
Sbjct: 452  RDRRRHSPRSRSQERRDREKERERRQKGLPQVKPETASVCSTTLWVGQLDKRTTQQDVAS 511

Query: 496  LFEEFGQIESINMIPPRGCAYVCMVHRQDAFRALQKLSSGSYKIGSKVIKIAWALNKGVK 555
            L EEFG IESINMIPPRGCAY+ MVHRQDA+RALQKLS G+YK+  K IKIAWALNKG+K
Sbjct: 512  LLEEFGPIESINMIPPRGCAYIVMVHRQDAYRALQKLSRGNYKVNQKSIKIAWALNKGIK 571

Query: 556  TEYKQFWDVDLGVTYIPWEKVKVDDLEGFAEGGMIDQETVNTEWETVKSSEPVKETVQT- 614
             +YKQ+WDV+LGVTYIPW+KVK ++LE F EGGM+D +T+N +W+ +   +P  E  Q  
Sbjct: 572  ADYKQYWDVELGVTYIPWDKVKPEELESFCEGGMLDSDTLNPDWKGI-PKKPENEVAQNG 630

Query: 615  ------TQSPTPVEKETVVTTQAEVFPPPVAM--LQIPV-APAVPTV-SLVPPAFPVSMP 664
                  T+  +P+ K   V       P P+ +   Q+P   P  P V +L PPAF   + 
Sbjct: 631  GAETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLG 690

Query: 665  VPPPGFS-----PIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPPPTIPP--VVPTSLVQ 717
            +PPPGF      P PPPPFLR  FNP   PPGF+PP  PPP+ PP +IPP    P S+  
Sbjct: 691  IPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPN 750

Query: 718  PSLS-MTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDH 776
             +++ +  +T KD+  G+                 P   V +     AE  + V      
Sbjct: 751  STIAGINEDTTKDLSIGN-----------------PIPTVVSGARGNAESGDSV------ 787

Query: 777  QISSGENTRSVIPNDISSNAAILGGQPPNVTSNSGILGVQRPNVSSNSEILGVRPSNVSS 836
                 +   S +P    +N        P VT    +LG Q           GV P  V  
Sbjct: 788  -----KMYGSAVPPAAPTNL-----PTPPVTQPVSLLGTQ-----------GVAPGPV-- 824

Query: 837  SSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGL 896
                              +G+Q P    S+GLLG                       PGL
Sbjct: 825  ------------------IGLQAP----STGLLGA---------------------RPGL 841

Query: 897  LGTQPPAGPQNLPPLSIPNQRMPTMPMLDIRPGLIPQAPGPRFPLIQPGIPPQRGIPPPS 956
            +  Q P G   +PP  +  QR P MP   + P ++ + P P         P    +PPP 
Sbjct: 842  IPLQRPPG---MPPPHL--QRFPLMPPRPMPPHMMHRGPPPG--------PGGFAMPPPH 888

Query: 957  VLDSALHPPPRGPFPPGDIFSQPERPFLAPGRQSVDNVTNPEKRIPLGNDNIQQEGDRDY 1016
             +        +GPFP       P  PF+ PG         P    P   D  QQ   +  
Sbjct: 889  GM--------KGPFP-------PHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQ 933

Query: 1017 RFPPIET-----RESISRPPPVDVRDVVGRPIDPREGPGRPPLDGRDHF--GRPPVDIRE 1069
            + P  +      ++   +PPP        +P   ++ P +   D R  F  GR       
Sbjct: 934  QQPQPQAPQQPQQQQQQQPPPSQ------QPPPTQQQPQQFRNDNRQQFNSGRDQ----- 982

Query: 1070 NLVRPGIDHLGRRDHFG---FNPEKPWGHRGDFDEREHRVLPVYGGPKGLHEERGRFRSG 1126
                   +  GRR  FG    N  + +G+R D  +  +R    +G               
Sbjct: 983  -------ERFGRRS-FGNRVENDRERYGNRNDDRDNSNRDRREWG--------------- 1019

Query: 1127 NYRFDPRSGPWNRGFGQEVHRDFDDRRR--PWERQRDRDDRDFDFCREMNGNRLGRDRIQ 1184
                        R   ++ HRD ++R R     R R+RD RD +  RE    R G+++ +
Sbjct: 1020 -----------RRSPDRDRHRDLEERNRRSSGHRDRERDSRDRESRREKEEAR-GKEKPE 1067

Query: 1185 -------NTWVPPPHARV 1195
                   N  V PP ++V
Sbjct: 1068 VTDRAGGNKTVEPPISQV 1085



 Score = 39.7 bits (91), Expect = 0.019
 Identities = 47/201 (23%), Positives = 77/201 (38%), Gaps = 20/201 (9%)

Query: 322  QQQPQKATPQDSQEGTFGSEHSASPSQGS--SQQHFLEPEVNLDDSIDIQQQDMDIDEGQ 379
            QQQPQ   PQ  Q+     +    PSQ    +QQ   +P+   +D+    +Q  +    Q
Sbjct: 933  QQQPQPQAPQQPQQQ---QQQQPPPSQQPPPTQQ---QPQQFRNDN----RQQFNSGRDQ 982

Query: 380  DGVEEEVFEQEAKKVAVRSRSRTHSRSRSRSPRK---RRSRSRSGSRKRKHRKRSRSRSR 436
            +      F    +    R  +R   R  S   R+   RRS  R   R  + R R  S  R
Sbjct: 983  ERFGRRSFGNRVENDRERYGNRNDDRDNSNRDRREWGRRSPDRDRHRDLEERNRRSSGHR 1042

Query: 437  ERKRKSSRSYSSERRAREREKERQKKGLPPIRSKTLSVCSTTLWVGQVDKKATQQDLTNL 496
            +R+R      S +R +R  ++E + K  P +  +     +    + QV    T  +L   
Sbjct: 1043 DRERD-----SRDRESRREKEEARGKEKPEVTDRAGGNKTVEPPISQVGNVDTASELEKG 1097

Query: 497  FEEFGQIESINMIPPRGCAYV 517
              E   ++    +P    + V
Sbjct: 1098 VSEAAVLKPSEELPAEATSSV 1118


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 1124

 Score = 87.8 bits (216), Expect = 6e-17
 Identities = 118/422 (27%), Positives = 160/422 (37%), Gaps = 82/422 (19%)

Query: 605  SEPVKETVQTTQSP--TPVEKETV-----VTTQAEVFPPPVAMLQIPVAP----AVPTVS 653
            S+P  + +Q  + P  TP  K+       +++     P P      PV P    A P  +
Sbjct: 270  SQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPA 329

Query: 654  LVPPAFPVSMPVPPPGFSPIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPPP---TIPPV 710
             +PP+ P++ P+P    SP  PP        P+ PP    P    PP+  PP   TIPP+
Sbjct: 330  TLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPI 389

Query: 711  -VPTSLVQPSLSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEPE-- 767
             VP SL  PSL   P                   S LA S+L A     +PT QA     
Sbjct: 390  QVPHSLTSPSLQAPP-------------------SPLALSSLQATTSLGSPTLQATHSFL 430

Query: 768  EKVPHLIDHQISSGENTRSVIPNDISSNAAI-LGGQPPNVTSNSGILGVQRPNVSSNSEI 826
               P      ++S     S  P+     A + L   PP  TS S       P VS  S  
Sbjct: 431  TMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLS-------PAVSPLSSP 483

Query: 827  LGVRPSNVSSSSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQ 886
            L + P    SS   +A+  P    +S I+   PP  + SS                  + 
Sbjct: 484  LTIHPLQALSS---LASHSPQAPLSSLIM---PPLETQSS------------------LA 519

Query: 887  PPNVPNTPGLLGTQPPAGPQNLPPLSIPNQRMPTMPMLDIRPGL-IPQAPGPRFPLIQPG 945
            PP++   P  L T P    +NLP L+ P  +  + P+    P L  P  P P  PL  P 
Sbjct: 520  PPSLQTPPASLTTPP---LENLPSLAPPPLQTASAPL--TTPHLETPPCPAP-CPLQAP- 572

Query: 946  IPPQRGIPPPSVLDSALHPPPRGP----FPP-GDIFSQPERPFLAPGRQSVDNVTNPEKR 1000
             P     PPP    S   PPP+ P     PP   + S P  P   P  Q+   +  P  +
Sbjct: 573  -PSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQ 631

Query: 1001 IP 1002
             P
Sbjct: 632  AP 633



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 116/477 (24%), Positives = 160/477 (33%), Gaps = 91/477 (19%)

Query: 617  SPTPVEKETVVTTQAEVFPPPVAM---LQIPVAPAVPTVSLVPPAFPVSMPVPPPGFSPI 673
            +P P++  +   T   +  PP      LQ P +P    ++  PP  P S+  PPP   P 
Sbjct: 542  APPPLQTASAPLTTPHLETPPCPAPCPLQAPPSP----LTTPPPETPSSIATPPPQAPPA 597

Query: 674  PPPPFLRASFNPSQPPPGFMPPPVPPPV-VPPPTIPPVVPTS-LVQPSLSMTPETVKDVG 731
               P L+   +P   P    PP  PP + +PP   PP  P S  + P  + +P+    + 
Sbjct: 598  LASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALA 657

Query: 732  FGSLVI-----PGGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDHQISSGENTRS 786
               L       P   V +  +  A P  +    P  QA P    P L             
Sbjct: 658  VHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPL------------Q 705

Query: 787  VIPNDISSNAAILGGQPPNVTSNSGILGVQRPNVSSNSEILGVRPSNVSSSSGIIAAQPP 846
            V P+  +S        PP           Q P   + +  L V PS  +S     +A PP
Sbjct: 706  VPPSPPASPPMSPSATPP----------PQAPPPLA-APPLQVPPSPPASPPMSPSATPP 754

Query: 847  NILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGLLGTQPPAGPQ 906
              +         PP       LL   P  +P +       P ++P +P  L   PP  P 
Sbjct: 755  PRV---------PP-------LLAAPPLQVPPS------PPASLPMSP--LAKPPPQAPP 790

Query: 907  NL--PPLSIPNQRMPTMPMLDIRPGLIPQAPGPRFPLIQPGIPPQRG----------IPP 954
             L  PPL    Q +P+ P     PG  P +P    P+     PP +           +PP
Sbjct: 791  ALATPPL----QALPSPPA--SFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPP 844

Query: 955  PSVLDSALHPPPRGPFPPGDIFSQPERPFLA--------PGRQSVDNVTNPEKRIPLGND 1006
                   L  P R P P  D      R  LA        P R     ++ P+      + 
Sbjct: 845  SPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSA 904

Query: 1007 NIQQEGDRDYRFPPIETRESISRPPPVDVRDVVGRPIDPREGPGRPPLDGRDHFGRP 1063
                E  R Y   P       +  PP D       P     GP  PPL  R   G P
Sbjct: 905  TSTPEELRGYDSGP---EGGAAASPPPDAELAACHPAAWSRGPA-PPLAFRGAPGAP 957



 Score = 61.6 bits (148), Expect = 5e-09
 Identities = 104/413 (25%), Positives = 136/413 (32%), Gaps = 63/413 (15%)

Query: 607 PVKETVQTTQSPTPVEKETVVTTQAEVFP-PPVAMLQIPVAPAVPTVSLVPP-AFPVSMP 664
           P  ET  +  +P P     + +   +  P PP++ L  P  P  P    +PP   P S P
Sbjct: 579 PPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATP-PPQAPPXLALPPLQAPPSPP 637

Query: 665 VPPPGFSPIPPPP----------FLRASFNPSQPPPGFMP--PPVPPPVVPPPTIPPVVP 712
             PP  SP+  P            L+A F+P   PP   P  PP  PPV P  T P   P
Sbjct: 638 ASPP-LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAP 696

Query: 713 TSLVQPSLSMTPETVKDVGFGSLVIPGGSVASNLATSAL---PAGNVFNAPTKQAEPEEK 769
            SL  P L + P             P       LA   L   P+       +  A P  +
Sbjct: 697 PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPR 756

Query: 770 VPHLIDHQISSGENTRSVIPNDISSNAAILGGQPPNVTSNSGILGVQRPNVSSNSEILGV 829
           VP L+            V P+  +S       +PP           Q P   +   +  +
Sbjct: 757 VPPLL------AAPPLQVPPSPPASLPMSPLAKPP----------PQAPPALATPPLQAL 800

Query: 830 RPSNVSSSSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQPPN 889
            PS  +S  G     P   L  S +    P +    +  L  +PP+ P +  L   Q P 
Sbjct: 801 -PSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTL---QAPR 856

Query: 890 VPNTPG------------LLGTQPPAGPQNLP--PLSIPNQRMPTMPMLDIRPGLIPQAP 935
            P TPG             L   PP  P   P   LS P+    +         L     
Sbjct: 857 RPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDS 916

Query: 936 GPRFPLIQPGIPPQRGIPPPSVLDSALHPP--PRGPFPPGDIFSQPERPFLAP 986
           GP               PPP    +A HP    RGP PP      P  P   P
Sbjct: 917 GPE--------GGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWP 961



 Score = 54.7 bits (130), Expect = 6e-07
 Identities = 42/124 (33%), Positives = 54/124 (43%), Gaps = 12/124 (9%)

Query: 605 SEPVKETVQTTQSPTPVEKETVVTTQAEVFPPPVAMLQIPVAPAVPTVSLVPPAFPVSMP 664
           S PV+       SP PV       +QA   PP +A   + V P+ P     PP  P + P
Sbjct: 670 SPPVQAPFSPPASP-PVSPSATPPSQA---PPSLAAPPLQVPPSPPAS---PPMSPSATP 722

Query: 665 VPPPGFSPIPPPPFLRASFNPSQPP--PGFMPPPVPPPVV--PPPTIPPVVPTSLVQPSL 720
            PP    P+  PP       P+ PP  P   PPP  PP++  PP  +PP  P SL    L
Sbjct: 723 -PPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPL 781

Query: 721 SMTP 724
           +  P
Sbjct: 782 AKPP 785



 Score = 53.9 bits (128), Expect = 9e-07
 Identities = 91/423 (21%), Positives = 152/423 (35%), Gaps = 42/423 (9%)

Query: 653  SLVPPAFPVSMPVPPPGFSPIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPP-----PTI 707
            SL   A P+S P      +   P    RA  +PSQP P  +    PP V PP     P +
Sbjct: 241  SLSSSATPLSSPARSGPSARGTP----RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL 296

Query: 708  PPVVPTSLVQPSLSMT------PETVKDVGFGSLVIPGGSVASNL-----ATSALPAGNV 756
             P+  + L  PS S T      P         + + P   +A+ L     + SA P+   
Sbjct: 297  GPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQT 356

Query: 757  FNAPTKQAEPEEKVPHLIDHQISSGENTRSV----IPNDISSNAAILGGQPPNVTSNSGI 812
              +P     P +  P +    + +  + +++    +P+ ++S +      P  ++S    
Sbjct: 357  LPSP-PATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQAT 415

Query: 813  LGVQRPNVSSNSEILGVRPSNVSSSSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLGVL 872
              +  P + +    L + P    +S     ++P +   +S  L   P S+  S  L   L
Sbjct: 416  TSLGSPTLQATHSFLTMSPRQTQASL-TSPSRPASTPPDSPPLQ-APLSLPASPPLQTSL 473

Query: 873  PPNIPNNSGLVGVQPPNVPNTPGLLGTQPPAGPQNLPPLSIPNQRMPTMPMLDIRPGLIP 932
             P +   S  + + P    ++      Q P     +PPL   +   P  P L   P  + 
Sbjct: 474  SPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAP--PSLQTPPASLT 531

Query: 933  QAPGPRFPLIQPGIPPQRGIPPPSVLDSALHPPPRGPFPPGDIFSQPERPFLAPGRQSVD 992
              P    P + P  PP +    P        PP   P P       P  P   P  ++  
Sbjct: 532  TPPLENLPSLAP--PPLQTASAPLTTPHLETPPCPAPCP----LQAPPSPLTTPPPETPS 585

Query: 993  NVTNPEKRIPLGNDNIQQEGDRDYRFPPIETRESISRPPPVDVRDVVGRPID-PREGPGR 1051
            ++  P  + P    +   +G      PP+     ++ PPP     +   P+  P   P  
Sbjct: 586  SIATPPPQAPPALASPPLQG---LPSPPL---SPLATPPPQAPPXLALPPLQAPPSPPAS 639

Query: 1052 PPL 1054
            PPL
Sbjct: 640  PPL 642



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 89/367 (24%), Positives = 129/367 (35%), Gaps = 73/367 (19%)

Query: 636 PPVAMLQIPVAPAVPTVSLVPPAFPVSMPVPPPGFSPIPP---PPFLRASFNPSQPPPGF 692
           PP++ L  P   A   +++     P S P  PP  +P  P   PP   ++  PSQ PP  
Sbjct: 640 PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSL 699

Query: 693 MPPPV--------PPPVVPPPTIPPVVPTSLVQPSLSMTPETVKDVGFGSLVIPGGSVAS 744
             PP+         PP+ P  T PP  P  L  P L + P             P   V  
Sbjct: 700 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPP 759

Query: 745 NLATSAL-----PAGNVFNAPTKQAEPEEKVPHLIDHQISSGENTRSVIPND--ISSNAA 797
            LA   L     P  ++  +P  +  P+   P L    + +  +  +  P     S +A+
Sbjct: 760 LLAAPPLQVPPSPPASLPMSPLAKPPPQAP-PALATPPLQALPSPPASFPGQAPFSPSAS 818

Query: 798 I----LGGQPPNVTSNSGILGVQRPNVSSNSEILGVRPSNVSSSSGIIAAQPPNILNNSG 853
           +    L   PP           Q P V + + +L V PS  +S +     +PP    ++ 
Sbjct: 819 LPMSPLATPPP-----------QAPPVLA-APLLQVPPSPPASPTLQAPRRPPTPGPDTS 866

Query: 854 ILGIQ-----------PPSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGLLGTQPP 902
           + G +           PPS S SS L G   P++  +S      P  +        + P 
Sbjct: 867 VSGPRLTLALAPGPPPPPSRSPSSTLSG---PDLAGHSSSATSTPEELRG----YDSGPE 919

Query: 903 AGPQNLPPLSIPNQRMPTMPMLDIRPGLIPQAPGPRFPLIQPGIPPQRGIPPPSVLDSAL 962
            G    PP        P   +    P    + P P  PL   G P   G P P       
Sbjct: 920 GGAAASPP--------PDAELAACHPAAWSRGPAP--PLAFRGAP---GAPLP------- 959

Query: 963 HPPPRGP 969
            PP  GP
Sbjct: 960 WPPATGP 966



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 59/226 (26%), Positives = 82/226 (36%), Gaps = 24/226 (10%)

Query: 602 VKSSEPVKETVQTTQSPTPVEKETVVTTQAEVFP-PPVAMLQIPVAPAVPTVS------- 653
           V  S P    +  + +P P     +     +V P PP +    P A   P V        
Sbjct: 706 VPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPP 765

Query: 654 -LVPPAFPVSMPV-----PPPGFSPIPPPPFLRASFNPSQPPPGFMP------PPVPPPV 701
             VPP+ P S+P+     PPP   P    P L+A  +P    PG  P       P+ P  
Sbjct: 766 LQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 825

Query: 702 VPPPTIPPVVPTSLVQ--PSLSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNA 759
            PPP  PPV+   L+Q  PS   +P T++         P  SV+    T AL  G     
Sbjct: 826 TPPPQAPPVLAAPLLQVPPSPPASP-TLQAPRRPPTPGPDTSVSGPRLTLALAPGPP-PP 883

Query: 760 PTKQAEPEEKVPHLIDHQISSGENTRSVIPNDISSNAAILGGQPPN 805
           P++        P L  H  S+      +   D           PP+
Sbjct: 884 PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPD 929



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 87/403 (21%), Positives = 135/403 (33%), Gaps = 70/403 (17%)

Query: 681  ASFNPSQPPPGFMPP-PVPPPVVPPPTIPPVVPTSLVQPSLSMTPETVKDVGFGSLVIP- 738
            A+  P+   PG + P P   P  PPP  P  +       ++   P   +  G G   IP 
Sbjct: 13   AARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPE 72

Query: 739  ----------GGSVASNLATSALPAGNVFNA-PTKQAEP-------------------EE 768
                       G+ + N A+    +G    A P K   P                   ++
Sbjct: 73   SAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQK 132

Query: 769  KVPHLIDHQISSGENTRSVIPNDISSNAAILGGQPPNVTSNSGI----------LGVQRP 818
             +    +  ++ G+ T +   + +S+ A      P   T +  +          +G+ RP
Sbjct: 133  GLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRP 192

Query: 819  NVSSNSEILGVRP-SNVSSSSGIIAAQPPNILNN--SGILGIQPPSVSNSSGLLGVLPPN 875
              S+        P  +VSS+S     +P        S   G+Q P+  + S      P +
Sbjct: 193  APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS--SATPLS 250

Query: 876  IPNNSGLVGVQPPNVPNTPGLLGTQP-PAGPQNLPPLSIPNQRMPTMPMLDIRPGLIPQA 934
             P  SG      P  P  P    +QP P G Q L P  +   R    P L          
Sbjct: 251  SPARSGPSARGTPRAPAHP----SQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLAT 306

Query: 935  PGPRFPLIQPGIPPQRG-------IPPPSVLDSALHPPPRGPFPPGDIFSQPERPFLAPG 987
            P P     +P  PP          +PP   L + L   P  P  P  + + P  P   P 
Sbjct: 307  PSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPP-ATPP 365

Query: 988  RQSVDNVTNPEKRIPLGNDNIQQEGDRDYRFPPIETRESISRP 1030
             Q+  ++T P  + P     I          PPI+   S++ P
Sbjct: 366  SQAPPSMTTPPMQAPPSLQTI----------PPIQVPHSLTSP 398


>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
          Length = 2217

 Score = 80.1 bits (196), Expect = 1e-14
 Identities = 109/430 (25%), Positives = 156/430 (36%), Gaps = 43/430 (10%)

Query: 594  TVNTEWETVKSSEPVKETVQTTQSP-----TPVEKETVVTTQAEVFPPPVAMLQIPVAPA 648
            TV ++ ++ + S  +        SP     +P   E  V  Q+   P   A  Q   AP 
Sbjct: 623  TVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQS--LPSLGAYQQPTAAPG 680

Query: 649  VPTVSLVPPAFPVSM----PVPPPGFSPIPPPPFLRASFNPSQP-PPGFMPPPVPPPVVP 703
            +P  S+  PA P S+    P P   F+P+ PPP       P QP PPG  PPP+  P   
Sbjct: 681  LPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPL 740

Query: 704  PPTIPP--VVPTSLVQPSLSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPT 761
            P  + P  VVP   V P L         VG  + + P       L     P   +   P 
Sbjct: 741  PQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKP-------LQMPQAPLQPLAQVPP 793

Query: 762  KQAEPEEKVPHLIDHQISSGENTRSVIPNDISSNAAILGGQPPNVTSNSGILGVQRPNVS 821
             Q  P   VP +    ++  +     +P+     A +    PP   S + IL      + 
Sbjct: 794  -QMPPIPVVPPITP--LAGIDGLPPALPD--LPTATVPPVPPPQYFSPAVILPSLAAPLP 848

Query: 822  SNSEILGVRPSNVSSSSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSG 881
              S  L ++   +    G   A P   +          P+   +  LL V PP +   S 
Sbjct: 849  PASPALPLQAVKLPHPPGAPLAMPCRTI---------VPNAPATIPLLAVAPPGVAALS- 898

Query: 882  LVGVQPPNVPNTPGLLGTQPPAGPQNLPPL---SIPNQRM-PTMPMLDIRPGLIPQAPGP 937
             +      +P  P      P   P ++PP    ++ N R  P  P L  +P L PQ   P
Sbjct: 899  -IHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLP 957

Query: 938  RFPLI--QPGIPPQRGIPPPSVLDSALHPPPRGPFPPGDIFSQPERPFLAPGRQSVDNVT 995
              P +  QP +PPQ   PP  VL      PP+   PP         P      +      
Sbjct: 958  PQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAA 1017

Query: 996  NPEKRIPLGN 1005
             P  +I LG+
Sbjct: 1018 TPGSQILLGH 1027



 Score = 40.0 bits (92), Expect = 0.014
 Identities = 109/468 (23%), Positives = 157/468 (33%), Gaps = 68/468 (14%)

Query: 610  ETVQTTQSPTPVEKETVVTTQAEVFPP-PVAMLQIPVAPA----VPTVSLVPPAFPVSMP 664
            E  + +Q+  PV ++ V+ T    F   PVA    P AP     +P  SL P A   S P
Sbjct: 1289 EESRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAPEAPESSPPLPLSSLPPEASQDSAP 1348

Query: 665  VPPPGFSPIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPPPTIPPV--VPTSLVQPSLSM 722
                  S    P FL +    SQ  P    PP  PP    P+ PPV  +P     P+ S 
Sbjct: 1349 YKDQ-LSSKEQPSFLASQQLLSQAGPS--NPPGAPPAPLAPSSPPVTALPQDGAAPATST 1405

Query: 723  TPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDHQISSGE 782
             PE            P    AS       P G      T Q   E     L    +  G 
Sbjct: 1406 MPE------------PASGTASQAGGPGTPQGLTSELETSQPLAETHEAPLAVQPLVVGL 1453

Query: 783  NTRSVIPNDISSNAAILGGQP--PNVTSNSGILGVQRPNVSSNSEILGVRPSNVSSSSG- 839
               +  P   S+  A    +P  P     S   G  +P +   + +L      VS ++  
Sbjct: 1454 APCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQ 1513

Query: 840  --------IIAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVP 891
                     +  QPP+ L + G     PP V      +  L   +        +   +VP
Sbjct: 1514 LPSPPLGPTVPPQPPSALESDG--EGPPPRVGFVDSTIKSLDEKLRTL-----LYQEHVP 1566

Query: 892  NTPGLLGTQPPAGPQN--LPPLSIPNQRMPTMPMLDIRPGLIPQAPGPRFPLIQPGIPPQ 949
             +    GT    G ++  L PL          P  ++  G +   P P+       +  +
Sbjct: 1567 TSSASAGTPVEVGDRDFTLEPLR------GDQPRSEVCGGDLALPPVPK-----EAVSGR 1615

Query: 950  RGIPPPSVLDSALHPPPRGPFPPGDIFSQPERP-------FLAPGRQSVDN---VTNPEK 999
              +P P V  S L P        G   S            +   GRQ   +   V +  +
Sbjct: 1616 VQLPQPLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQ 1675

Query: 1000 RIPLGNDNIQQEG-DRDYRFPPIETRESISRPPPVDVRDVVGRPIDPR 1046
             +P      + E  DRD      E  ES + PPP D+  V G+   P+
Sbjct: 1676 DVPAFVRPARVEPTDRDGG----EAGESSAEPPPSDMGTVGGQASHPQ 1719



 Score = 39.7 bits (91), Expect = 0.019
 Identities = 55/203 (27%), Positives = 74/203 (36%), Gaps = 32/203 (15%)

Query: 617  SPTPVEKETVVTTQAEVFPPPVAMLQIPVAPAVPTVSLVPPAFPVSMPVPPPGFSPIPPP 676
            SP    +    T      PP   +   PV P  PT   +PP      PV PP   P  PP
Sbjct: 927  SPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPT---LPP-----QPVLPP--QPTRPP 976

Query: 677  PFLRASFNPSQPPPGFMPPPVPPPVVPPPTIPPVVPTSLVQPSLSMTPETVKDVGF-GSL 735
                    P  PP   +P   P PV+PP    PV P  L QP L   PE        GS 
Sbjct: 977  -------QPVLPPQPMLP---PQPVLPPQPALPVRPEPL-QPHL---PEQAAPAATPGSQ 1022

Query: 736  VIPGG------SVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDHQISSGENTRSVIP 789
            ++ G        VA+ + T  +P   V + P  +       P L+    SS     + + 
Sbjct: 1023 ILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEV-LLPAAPELLPQFPSSLATVSASVQ 1081

Query: 790  NDISSNAAILGGQPPNVTSNSGI 812
            +  +  A +L    P +    GI
Sbjct: 1082 SVPTQTATLLPPANPPLPGGPGI 1104



 Score = 35.0 bits (79), Expect = 0.46
 Identities = 43/167 (25%), Positives = 60/167 (35%), Gaps = 22/167 (13%)

Query: 611  TVQTTQS--PTPVEKETVVTTQAEVFPPPVAMLQIPVAPAVPTVSLVPPAFPVSMPVPPP 668
            TVQ  ++  P P            V PP   +   PV P  PT    P   P  M  P P
Sbjct: 931  TVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQP 990

Query: 669  GFSPIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPPPTI------PPVVPTSLVQPSLSM 722
                +PP P L     P QP    +P    P   P   I      P  V  +   P++ +
Sbjct: 991  ---VLPPQPALPVRPEPLQP---HLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPV 1044

Query: 723  TPETVKDVGFGSLVIPGG-----SVASNLATSALPAGNVFNAPTKQA 764
             P  V       +++P          S+LAT    + +V + PT+ A
Sbjct: 1045 PPAAVLSPPLPEVLLPAAPELLPQFPSSLAT---VSASVQSVPTQTA 1088


>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
            1 [Homo sapiens]
          Length = 1250

 Score = 77.4 bits (189), Expect = 8e-14
 Identities = 103/401 (25%), Positives = 147/401 (36%), Gaps = 85/401 (21%)

Query: 672  PIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPPPTIPPVVPTSLVQPSLSMTPETVKDVG 731
            P+ P P +   +  SQP P   PPP PPP  PPP  PP  P         +  ++    G
Sbjct: 608  PLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPP---------LPSQSAPSAG 658

Query: 732  FGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDHQISSGENTRSVIPND 791
              + +    S  + L  ++  +G +F  PT         P ++  Q        SV P  
Sbjct: 659  SAAPMFVKYSTITRLQNASQHSGALFKPPT---------PPVMQSQ--------SVKPQI 701

Query: 792  ISSNAAILGGQPPNVTSNSGILGVQRPNVSSNSEILGVRPSNVSSSSGIIAAQPP--NIL 849
            +     ++   PP             P  +  S +  ++P+  + S    +A PP   I 
Sbjct: 702  LVPPNGVVPPPPP-----------PPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIH 750

Query: 850  NNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGLLGTQPPAGPQNLP 909
                I  + PP+      +   LPP  P    LV +  P    T   + TQ  A P   P
Sbjct: 751  QVQHITQVAPPTPPPPPPIPAPLPPQAPPKP-LVTIPAPTSTKTVAPVVTQ-AAPPTPTP 808

Query: 910  PLSIPNQRMPTMPMLDIRPGLIPQAPGPRFPLIQPGIPPQRGI---PPPSVLD------- 959
            P+  P ++ P  P   I     P  P P  P+  P +P Q+     PPPS L        
Sbjct: 809  PVP-PAKKQPAFPASYIP----PSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVK 863

Query: 960  --SALHPPPRGPFPPGDIFSQPERPFLA-PGRQSVDNVTNPEK----RIPLGNDNIQQEG 1012
              ++  PPP  P PP  + SQP +P  A    QS   V    K     IP+ + +     
Sbjct: 864  QIASQFPPP--PTPPA-MESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPD----- 915

Query: 1013 DRDYRFPPIETRESISRPPPVDVRDVVGRPIDPREGPGRPP 1053
                 FPP     S+  PPP         P  P   P  PP
Sbjct: 916  -----FPPPPPESSLVFPPP---------PPSPVPAPPPPP 942



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 113/505 (22%), Positives = 169/505 (33%), Gaps = 112/505 (22%)

Query: 605  SEPVKETVQTTQSPTPVEKETVVTTQAEVFPP--PVAMLQIPVAPAVPTVSLVPPAFPVS 662
            SE  K   Q  +S +    E++      + PP  P   +  P   + P+  L PP  P  
Sbjct: 578  SEAWKRGTQLEES-SKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPP 636

Query: 663  MPVPPPGFSPIPPPP---------------FLRASF-----NPSQPPPGFMPPPVPP--- 699
             P PPP   P PPPP               F++ S      N SQ       PP PP   
Sbjct: 637  PPPPPP---PPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQ 693

Query: 700  -------------PVVPPPTIPPVVPTSLVQPSLSMTPETVKDVGFGSLVIPGGSVASNL 746
                          VVPPP  PP  PT                        PG ++A   
Sbjct: 694  SQSVKPQILVPPNGVVPPPPPPPPPPT------------------------PGSAMAQLK 729

Query: 747  ATSALPAGNVFNAPTKQAEPEEKVPHLIDHQISSGENTRSVIPNDISSNAAILGGQPPNV 806
                 P+   F+AP          P L  HQ+   ++   V P        I    PP  
Sbjct: 730  PAPCAPSLPQFSAPP---------PPLKIHQV---QHITQVAPPTPPPPPPIPAPLPPQA 777

Query: 807  TSNSGILGVQRPNVSSNSEILGVRPSNVSSSSGIIAAQPPNILNNSGILGIQPPSVSNSS 866
                 ++ +  P  +     +  + +  + +  +  A+       S I    PPS     
Sbjct: 778  PPKP-LVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYI----PPSPPTPP 832

Query: 867  GLLGVLPPNIPNNSGLVGVQPPN----VPNTPGLLGTQPPAGPQNLPPLSIPNQRMPTMP 922
              + V PP +P         PP+    VP+    + +Q P  P   PP       M + P
Sbjct: 833  --VPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFP--PPPTPP------AMESQP 882

Query: 923  MLDIRPGLIPQAPG--PRFPLIQP-GIP-PQRGIPPPSVLDSALHPP------PRGPFPP 972
            +  +   + PQ+P      P  QP  IP P    PPP    S + PP      P  P PP
Sbjct: 883  LKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPP 942

Query: 973  GDIFSQPERPFLAPGRQSVDNVTNPEKR---IPLGNDNIQQEGDRDYRFPPIETRESI-- 1027
                S       +PG+++    +   K+    P  N +I+     ++  P   + +S+  
Sbjct: 943  PPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVS 1002

Query: 1028 SRPPPVDVRDVVGRPIDPREGPGRP 1052
               PP +        + P   P +P
Sbjct: 1003 KFTPPAESGSPSKETLPPPAAPPKP 1027



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 78/329 (23%), Positives = 113/329 (34%), Gaps = 54/329 (16%)

Query: 607  PVKETVQTTQSPTPVEKETVVTTQ-AEVFPPPV---AMLQIPVAP--------AVPTVSL 654
            P +++      P+P+     V  Q A  FPPP    AM   P+ P        + P V  
Sbjct: 841  PKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKA 900

Query: 655  VPPAFPVSMPVPPPGFSPIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPP---------- 704
             P   P S+PVP P F   PPPP     F P  P P   PPP PPP   P          
Sbjct: 901  KPKWQPSSIPVPSPDFP--PPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGK 958

Query: 705  PTIPPVVPTSLVQPSLSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQA 764
             T     P     P       ++K         P      +L +   P      +P+K+ 
Sbjct: 959  KTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAE-SGSPSKET 1017

Query: 765  EPEEKVPHLIDHQISSGENTRSVIPND-ISSNAAILGGQ------------------PPN 805
             P    P        SG N   V+    +S+ A +L G+                  PP 
Sbjct: 1018 LPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPP 1077

Query: 806  VTSNSGILGVQRP-----NVSSNSEILGVRPSNVSSSSGIIAAQPPNILNNSGILGIQPP 860
              +   +  ++ P     N S    ++  +P   S  S +  A PP     +    +   
Sbjct: 1078 PETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMS-VKKAPPPTRPKRNDSTRLTQA 1136

Query: 861  SVSNSSGLLGVLP--PNIPNNSGLVGVQP 887
             +S    +  V+P  P  P +S  + VQP
Sbjct: 1137 EISEQPTMATVVPQVPTSPKSS--LSVQP 1163



 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 108/474 (22%), Positives = 158/474 (33%), Gaps = 91/474 (19%)

Query: 606  EPVKETVQTTQSPTP---VEKETVVTTQAEVFPPPV---AMLQIPVAPAVPTVSLVPPAF 659
            +P    V  +QS  P   V    VV       PPP    AM Q+  AP  P++       
Sbjct: 685  KPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSL------- 737

Query: 660  PVSMPVPPPGFSPIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPPPTIPPVVPTSLVQPS 719
                    P FS  PPP  +    + +Q  P   PPP P P   PP  PP    ++  P+
Sbjct: 738  --------PQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPT 789

Query: 720  LSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDHQIS 779
             + T                    + + T A P       PT    P +K P      I 
Sbjct: 790  STKT-------------------VAPVVTQAAPP-----TPTPPVPPAKKQPAFPASYIP 825

Query: 780  SGENTR--SVIPNDISSNAAILGGQPPN----VTSNSGILGVQRP----NVSSNSEILGV 829
                T    V P  +    +     PP+    V S    +  Q P      +  S+ L  
Sbjct: 826  PSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKP 885

Query: 830  RPSNVS-SSSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQPP 888
             P+NV+  S   + A+P    ++  +     P     S L+   PP  P     V   PP
Sbjct: 886  VPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSP-----VPAPPP 940

Query: 889  NVPNTPGLLGTQPPAGPQNLPPLSIPNQRMPTMPMLDIRPGLIPQAPGPRFPLIQPGIPP 948
              P T      +  +  +     S P  + P  P    R   I  + G   P       P
Sbjct: 941  PPPPTASPTPDKSGSPGKKTSKTSSPGGKKP--PPTPQRNSSIKSSSGAEHP------EP 992

Query: 949  QRGIPPPSVLDSALHPPPRGPFPPGDIFSQPERPFLAPGRQSVDNVTNP--------EKR 1000
            +R  P    L S   PP     P  +    P  P   PG+ ++  V  P          +
Sbjct: 993  KR--PSVDSLVSKFTPPAESGSPSKETLPPPAAP-PKPGKLNLSGVNLPGVLQQGCVSAK 1049

Query: 1001 IPL----GNDNIQQ----EGDRDYRFPPIETRESISRPPPVDVRDVVGRPIDPR 1046
             P+    G D++ +      D D+  PP ET   +   PP+++  V      P+
Sbjct: 1050 APVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPL---PPIEIPAVFSGNTSPK 1100


>gi|160707881 formin 2 [Homo sapiens]
          Length = 1722

 Score = 72.0 bits (175), Expect = 3e-12
 Identities = 105/391 (26%), Positives = 137/391 (35%), Gaps = 62/391 (15%)

Query: 618  PTPVEKETVVTTQAEVFPPPVAMLQIPVAPAVPTVSLVPPAFPVSMPVPPP--GFSPIPP 675
            P P+   TV T  +   P P  +    + P  P     PP     +P PPP  G   +P 
Sbjct: 880  PPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPP-----PPLPGAGIPPPPPLPGAGILPL 934

Query: 676  PPFLRASFNPSQPPPGFMPPPVPPPVVPPPTIPPVVPTSLVQPSLSMTPETVKDVGF-GS 734
            PP   A   P  P PG   PP PP       +PP +P + + P     P  +   G    
Sbjct: 935  PPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPP-----PPPLPGAGIPPP 989

Query: 735  LVIPGGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDHQISSGENTRSVIPNDISS 794
              +PG  +        LP   +   P          P L      +G      +P     
Sbjct: 990  PPLPGAGIP---PPPPLPGAGIPPPPPLPGAGIPPPPPL----PGAGIPPPPPLPG---- 1038

Query: 795  NAAILGGQPPNVTSNSGI--------LGVQRPNVSSNSEILGVRPSNVSSSSGIIAAQPP 846
                 G  PP     +GI         G+  P     +   G+ P      +GI    PP
Sbjct: 1039 ----AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA---GIPPPPPLPGAGI---PPP 1088

Query: 847  NILNNSGI--------LGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGLLG 898
              L  +GI        +GI PP     +G+    PP +P      G+ PP  P  PG   
Sbjct: 1089 PPLPGAGIPPPPPLPGVGIPPPPPLPGAGI--PPPPPLPG----AGIPPP--PPLPGAGI 1140

Query: 899  TQPPAGPQ--NLPPLSIPNQRMPTMPMLDIRPGLIPQAPGPRFPLIQPGIPPQRGIPPPS 956
              PP  P+    PP  +P   +P  P L    G+ P  P P   +  P   P  GIPPP 
Sbjct: 1141 PPPPPLPRVGIPPPPPLPGAGIPPPPPLP-GAGIPPPPPLPGVGIPPPPPLPGVGIPPPP 1199

Query: 957  VLDSALHPPPRGPFPPGDIFSQPERPFLAPG 987
             L  A  PPP  P P   I   P  P   PG
Sbjct: 1200 PLPGAGIPPP-PPLPGMGIPPAPAPPLPPPG 1229



 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 98/362 (27%), Positives = 129/362 (35%), Gaps = 65/362 (17%)

Query: 635  PPPVAMLQIPVAPAVPTVSLVPP----AFPVSMPVPPPGFSPIPPPPFLRASFNPSQPPP 690
            PPP+    IP+ P +P   + PP       +  P P PG    PPPP   A   P  P P
Sbjct: 956  PPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1015

Query: 691  GF-MPPPVPPP---VVPPPTIPPV-VPTSLVQPSLSMTPETVKDVGFGSLVIPGGSVASN 745
            G  +PPP P P   + PPP +P   +P     P   + P            +PG  +   
Sbjct: 1016 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP---------LPGAGIPP- 1065

Query: 746  LATSALPAGNVFNAPTKQAEPEEKVPHLIDHQISSGENTRSVIPNDISSNAAILGGQPPN 805
                 LP   +   P          P L      +G      +P         +G  PP 
Sbjct: 1066 --PPPLPGAGIPPPPPLPGAGIPPPPPLP----GAGIPPPPPLPG--------VGIPPPP 1111

Query: 806  VTSNSGILGVQRPNVSSNSEILGVRPSNVSSSSGIIAAQPPNILNNSGI--------LGI 857
                +GI     P +       G+ P      +GI    PP  L   GI         GI
Sbjct: 1112 PLPGAGI--PPPPPLPG----AGIPPPPPLPGAGI---PPPPPLPRVGIPPPPPLPGAGI 1162

Query: 858  QPPSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGLLGTQPPA---GPQNLPPLSIP 914
             PP     +G+    PP +P     VG+ PP  P  PG+ G  PP    G    PP  +P
Sbjct: 1163 PPPPPLPGAGIPP--PPPLPG----VGIPPP--PPLPGV-GIPPPPPLPGAGIPPPPPLP 1213

Query: 915  NQRMPTMPMLDIRPGLIPQAPGPRFPLIQPGIPPQRG---IPPPSVLDSALHPPPRGPFP 971
               +P  P   + P      P P  P+  P + PQ G   +P P V      P P G F 
Sbjct: 1214 GMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLPSGLFG 1273

Query: 972  PG 973
             G
Sbjct: 1274 LG 1275



 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 112/419 (26%), Positives = 156/419 (37%), Gaps = 67/419 (15%)

Query: 583  GFAEGGMIDQETVNTEWETVKSSEPVKETVQTTQSPTPVEKETVVTTQAEVFPPPVAMLQ 642
            G  + G     +++TE++T            +   P+P     +  T++    P + M+ 
Sbjct: 821  GQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSP---PPLPCTESSSSMPGLGMVP 877

Query: 643  IPVAPAVPTVSLVPPAFPVSMPVPPP--GFS--PIPPPPFLRASFNPSQPPP--GFMP-P 695
             P  P +P ++ VP     ++P PPP  G    P PPPP   A   P  P P  G +P P
Sbjct: 878  -PPPPPLPGMT-VPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLP 935

Query: 696  PVPPPVVPPPTIPPVVPTSLVQPSLSMTPETVKDVGFG-SLVIPGGSVASNLATSALPAG 754
            P+P   +PP   PP +P + + P     P  +   G      +PG  +        LP  
Sbjct: 936  PLPGAGIPP---PPPLPGAAIPP-----PPPLPGAGIPLPPPLPGAGIP---PPPPLPGA 984

Query: 755  NVFNAPTKQAEPEEKVPHLIDHQISSGENTRSVIPNDISSNAAILGGQPPNVTSNSGILG 814
             +   P          P L      +G      +P          G  PP     +GI  
Sbjct: 985  GIPPPPPLPGAGIPPPPPL----PGAGIPPPPPLPG--------AGIPPPPPLPGAGI-- 1030

Query: 815  VQRPNVSSNSEILGVRPSNVSSSSGIIAAQPPNILNNSGI--------LGIQPPSVSNSS 866
               P +       G+ P      +GI    PP  L  +GI         GI PP     +
Sbjct: 1031 PPPPPLPG----AGIPPPPPLPGAGI---PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 1083

Query: 867  GLLGVLPPNIPNNSGLVGVQPPNVPNTPGLLGTQPP---AGPQNLPPLSIPNQRMPTMPM 923
            G+    PP +P      G+ PP  P  PG +G  PP    G    PP  +P   +P  P 
Sbjct: 1084 GI--PPPPPLPG----AGIPPP--PPLPG-VGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1134

Query: 924  LDIRPGLIPQAPGPRFPLIQPGIPPQRGIPPPSVLDSALHPPPRGPFPPGDIFSQPERP 982
            L    G+ P  P PR  +  P   P  GIPPP  L  A  PPP  P P   I   P  P
Sbjct: 1135 LP-GAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPP-PPLPGVGIPPPPPLP 1191



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 119/444 (26%), Positives = 154/444 (34%), Gaps = 96/444 (21%)

Query: 635  PPPVAMLQIPVAPAVPTVSLVPPAFPV--SMPVPPPGFSPIPPPPFLRASFNPSQPPPGF 692
            PPP+   +   + ++P + +VPP  P    M VP    + IP PP L+ +     PPP  
Sbjct: 858  PPPLPCTES--SSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGT--EMLPPP-- 911

Query: 693  MPPPVPPPVVPPPTIPPVVPTSLVQPSLSMTPETVKDVGFGSLVIPGGSVASNLATSALP 752
             PPP+P   +PPP   P +P                  G G L +P    A       LP
Sbjct: 912  -PPPLPGAGIPPP---PPLP------------------GAGILPLPPLPGAGIPPPPPLP 949

Query: 753  AGNVFNAPTKQAEPEEKVPHLIDHQISSGENTRSVIPNDISSNAAILGGQPPNVTSNSGI 812
               +   P     P   +P                +P  +       G  PP     +GI
Sbjct: 950  GAAI---PPPPPLPGAGIP----------------LPPPLPG----AGIPPPPPLPGAGI 986

Query: 813  LGVQRPNVSSNSEILGVRPSNVSSSSGIIAAQPPNILNNSGI--------LGIQPPSVSN 864
                 P +       G+ P      +GI    PP  L  +GI         GI PP    
Sbjct: 987  --PPPPPLPG----AGIPPPPPLPGAGI---PPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1037

Query: 865  SSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGLLGTQPPA---GPQNLPPLSIPNQRMPTM 921
             +G+    PP +P      G+ PP  P  PG  G  PP    G    PP  +P   +P  
Sbjct: 1038 GAGIPP--PPPLPG----AGIPPP--PPLPGA-GIPPPPPLPGAGIPPPPPLPGAGIPPP 1088

Query: 922  PMLDIRPGLIPQAPGPRFPLIQPGIPPQRGIPPPSVLDSALHPPPRGPFPPGDIFSQPER 981
            P L    G+ P  P P   +  P   P  GIPPP  L  A  PPP  P P   I   P  
Sbjct: 1089 PPLP-GAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPP-PLPGAGIPPPPPL 1146

Query: 982  PFLA-PGRQSVDNVTNPEKRIPLGNDNIQQEGDRDYRFPPIETRESISRPPPVDVRDVVG 1040
            P +  P    +     P    PL    I          PP      +  PPP  +  V  
Sbjct: 1147 PRVGIPPPPPLPGAGIPPPP-PLPGAGI----------PPPPPLPGVGIPPPPPLPGVGI 1195

Query: 1041 RPIDPREGPGRPPLDGRDHFGRPP 1064
             P  P  G G PP       G PP
Sbjct: 1196 PPPPPLPGAGIPPPPPLPGMGIPP 1219



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 105/409 (25%), Positives = 136/409 (33%), Gaps = 67/409 (16%)

Query: 699  PPVVPPPTIPPVVPTSLVQPSLSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFN 758
            PPV   P  PP  P +   P      E    V    + +   S     + S  P      
Sbjct: 758  PPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSLL 817

Query: 759  APTKQAEPEEKVPHLI--------DHQISSGENTRSVIPN-------DISSNAAILGGQP 803
                Q +P  + PH I        +H +SS       IP+       + SS+   LG  P
Sbjct: 818  WSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVP 877

Query: 804  PNVTSNSGIL-------GVQRPNVSSNSEILGVRPSNVSSSSGIIAAQPPNILNNSGIL- 855
            P      G+         + +P     +E+L   P  +  +       PP  L  +GIL 
Sbjct: 878  PPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAG----IPPPPPLPGAGILP 933

Query: 856  -------GIQPPSVSNSSGL--------LGV-LPPNIPNNSGLVGVQPPNVPNTPGLLGT 899
                   GI PP     + +         G+ LPP +P      G+ PP  P  PG  G 
Sbjct: 934  LPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPG----AGIPPP--PPLPGA-GI 986

Query: 900  QPPA---GPQNLPPLSIPNQRMPTMPMLDIRPGLIPQAPGPRFPLIQPGIPPQRGIPPPS 956
             PP    G    PP  +P   +P  P L    G+ P  P P   +  P   P  GIPPP 
Sbjct: 987  PPPPPLPGAGIPPPPPLPGAGIPPPPPLP-GAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1045

Query: 957  VLDSALHPPPRGPFPPGDIFSQPERPFLA-PGRQSVDNVTNPEKRIPLGNDNIQQEGDRD 1015
             L  A  PPP  P P   I   P  P    P    +     P    PL    I       
Sbjct: 1046 PLPGAGIPPP-PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP-PLPGAGI------- 1096

Query: 1016 YRFPPIETRESISRPPPVDVRDVVGRPIDPREGPGRPPLDGRDHFGRPP 1064
               PP      +  PPP  +      P  P  G G PP       G PP
Sbjct: 1097 ---PPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1142


>gi|16554449 zonadhesin isoform 3 [Homo sapiens]
          Length = 2812

 Score = 71.6 bits (174), Expect = 4e-12
 Identities = 82/392 (20%), Positives = 142/392 (36%), Gaps = 63/392 (16%)

Query: 591  DQETVNTEWETVKSSEPVKETVQTTQSPT----PVEKETVVTTQAEV--FPPPVAMLQIP 644
            ++ T++TE  TV + EP   T +TT S      P EK ++ T +  +    P ++M +  
Sbjct: 645  EKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704

Query: 645  VAPAVPTVSLVPPAFPVSMPVPPPGFSPIPPP-----------PFLRASFNPSQPPPGFM 693
            ++   PT+S   P  P   P  P   S I P            P  + + +P +P     
Sbjct: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTE 764

Query: 694  PPPVPP---------PVVPP--PTIP----------PVVPT-----SLVQPSLSM----- 722
             P + P         P +P   PTIP          P  PT     S  +PS+ M     
Sbjct: 765  KPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTL 824

Query: 723  -TPETVKDV-----GFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDH 776
             T ET   V         L IP      +     +P      +P K   P EK+      
Sbjct: 825  PTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT----- 879

Query: 777  QISSGENTRSVIPNDISSNAAILGGQPPNVTSNSGILGVQRPNVSSNSEILGVRPSNVSS 836
             I + + T  +    IS+    +  + P ++     +  ++P + +    +    + +S+
Sbjct: 880  -IPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTIST 938

Query: 837  SSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGL 896
                I  + P I      +  + P++S     +      IP     +  + P +P T  L
Sbjct: 939  EKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP-TEKL 997

Query: 897  LGTQPPAGPQNLPPLS--IPNQRMPTMPMLDI 926
               +PP        L+  + +   P+ PM  +
Sbjct: 998  TALRPPHPSPTATGLAALVMSPHAPSTPMTSV 1029



 Score = 54.3 bits (129), Expect = 7e-07
 Identities = 61/331 (18%), Positives = 118/331 (35%), Gaps = 27/331 (8%)

Query: 726  TVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDHQISSGENTR 785
            T   V  G ++I  G+    +     P      +P     P E      +  IS+ + T 
Sbjct: 518  TASVVAMGFILINPGTCPVKVLPELPPV-----SPVSSTGPSETTGLTENPTISTKKPTV 572

Query: 786  SVIPNDISSNAAILGGQPPNVTSNSGILGVQRPNVSSNSEILGVRPSNVSSSSGIIAAQP 845
            S+    +++    +  + P + +    +  ++P + S    +      + S    I  + 
Sbjct: 573  SIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEK 632

Query: 846  PNILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGLLGTQPPAGP 905
            P I +    +  + P++S     +    P  P       ++ P +P     + T+ P+ P
Sbjct: 633  PTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIP 692

Query: 906  QNLPPLSIPNQRMPTMPMLDIRPGLIPQAPGPRFPLIQPGIPPQRGIPPPSVLDSALHPP 965
               P +S+    + T      +P + P+   P  P  +P IP ++    P   +    P 
Sbjct: 693  TEKPTISMEETIISTE-----KPTISPEK--PTIPTEKPTIPTEKSTISP---EKPTTPT 742

Query: 966  PRGPFPPGDIFSQPERPFLAPGRQSV--DNVTNPEKR--IPLGNDNIQQEGDRDYRFPPI 1021
             +   P       PE+P     + ++  + +T P ++  IP     I  E       P I
Sbjct: 743  EKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEK------PTI 796

Query: 1022 ETRESISRPPPVDVRDVVGRPIDPREGPGRP 1052
             T E  +  P  +      +P  P E P  P
Sbjct: 797  STEEPTT--PTEETTISTEKPSIPMEKPTLP 825



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 51/267 (19%), Positives = 98/267 (36%), Gaps = 24/267 (8%)

Query: 700 PVVPPPTIPPVVPTSLVQPS--LSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVF 757
           PV   P +PPV P S   PS    +T          ++ I   SV +   T       + 
Sbjct: 535 PVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTI- 593

Query: 758 NAPTKQAEPEEKVPHLIDHQISSGENTRSVIPND---ISSNAAILGGQPPNVTSNSGILG 814
             PT++     + P  I  +  +  + +  IP++   I +    +  + P + S    + 
Sbjct: 594 --PTEKPTISTEKP-TIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTIS 650

Query: 815 VQRPNVSSNSEILGVRPSNVSSSSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPP 874
            ++P V +         +  S    +I  + P+I      +  + P++S    ++    P
Sbjct: 651 TEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKP 710

Query: 875 NIPNNSGLVGVQPPNVPNTPGLLGTQPPAGPQNLPPLSIPNQR------MPTMPMLDIRP 928
            I      +  + P +P     +  + P  P   P  +IP ++       PT P    +P
Sbjct: 711 TISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKP--TIPTEKPTISPEKPTTP--TEKP 766

Query: 929 GLIPQ-----APGPRFPLIQPGIPPQR 950
            + P+        P  P  +P IP ++
Sbjct: 767 TISPEKLTIPTEKPTIPTEKPTIPTEK 793



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 77/398 (19%), Positives = 127/398 (31%), Gaps = 90/398 (22%)

Query: 588 GMIDQETVNTEWETVKSSEPVKETVQTTQSPT-PVEKETVVTTQAEVFPPPVAMLQIPVA 646
           G+ +  T++T+  TV   +P      TT+ PT P EK T+ T +                
Sbjct: 558 GLTENPTISTKKPTVSIEKPSV----TTEKPTVPKEKPTIPTEK---------------- 597

Query: 647 PAVPTVSLVPPAFPVSMPVPPPGFSPIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPPPT 706
              PT+S   P  P   P  P     IP           S+ P      P  P     PT
Sbjct: 598 ---PTISTEKPTIPSEKPNMPSEKPTIP-----------SEKPTILTEKPTIPS--EKPT 641

Query: 707 IPPVVPTSLVQPSLSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEP 766
           IP   PT   +     T E            P     +++    +P         K + P
Sbjct: 642 IPSEKPTISTEKPTVPTEEPTT---------PTEETTTSMEEPVIPTEKPSIPTEKPSIP 692

Query: 767 EEKVPHLIDHQISSGENTRSVIPNDISSNAAILGGQPPNVTSNSGILGVQRPNVSSNSEI 826
            EK                      IS    I+  + P ++     +  ++P + +    
Sbjct: 693 TEKPT--------------------ISMEETIISTEKPTISPEKPTIPTEKPTIPTEKST 732

Query: 827 LGVRPSNVSSSSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQ 886
           +        +    I  + P I         + P++S     +    P IP     +  +
Sbjct: 733 ISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTE 792

Query: 887 PPNV----PNTP---GLLGTQPPAGPQNLPPL------------SIPNQRMPTMPMLDIR 927
            P +    P TP     + T+ P+ P   P L            +I  +++ T+PM   +
Sbjct: 793 KPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKL-TIPM--EK 849

Query: 928 PGLIPQAPGPRFPLIQPGIPPQRGIPPPSVLDSALHPP 965
           P +  +   P  P  +P I P++   P   L      P
Sbjct: 850 PTISTEK--PTIPTEKPTISPEKLTIPTEKLTIPTEKP 885


>gi|27881494 zonadhesin isoform 6 [Homo sapiens]
          Length = 2721

 Score = 71.6 bits (174), Expect = 4e-12
 Identities = 82/392 (20%), Positives = 142/392 (36%), Gaps = 63/392 (16%)

Query: 591  DQETVNTEWETVKSSEPVKETVQTTQSPT----PVEKETVVTTQAEV--FPPPVAMLQIP 644
            ++ T++TE  TV + EP   T +TT S      P EK ++ T +  +    P ++M +  
Sbjct: 645  EKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704

Query: 645  VAPAVPTVSLVPPAFPVSMPVPPPGFSPIPPP-----------PFLRASFNPSQPPPGFM 693
            ++   PT+S   P  P   P  P   S I P            P  + + +P +P     
Sbjct: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTE 764

Query: 694  PPPVPP---------PVVPP--PTIP----------PVVPT-----SLVQPSLSM----- 722
             P + P         P +P   PTIP          P  PT     S  +PS+ M     
Sbjct: 765  KPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTL 824

Query: 723  -TPETVKDV-----GFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDH 776
             T ET   V         L IP      +     +P      +P K   P EK+      
Sbjct: 825  PTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT----- 879

Query: 777  QISSGENTRSVIPNDISSNAAILGGQPPNVTSNSGILGVQRPNVSSNSEILGVRPSNVSS 836
             I + + T  +    IS+    +  + P ++     +  ++P + +    +    + +S+
Sbjct: 880  -IPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTIST 938

Query: 837  SSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGL 896
                I  + P I      +  + P++S     +      IP     +  + P +P T  L
Sbjct: 939  EKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP-TEKL 997

Query: 897  LGTQPPAGPQNLPPLS--IPNQRMPTMPMLDI 926
               +PP        L+  + +   P+ PM  +
Sbjct: 998  TALRPPHPSPTATGLAALVMSPHAPSTPMTSV 1029



 Score = 54.3 bits (129), Expect = 7e-07
 Identities = 61/331 (18%), Positives = 118/331 (35%), Gaps = 27/331 (8%)

Query: 726  TVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDHQISSGENTR 785
            T   V  G ++I  G+    +     P      +P     P E      +  IS+ + T 
Sbjct: 518  TASVVAMGFILINPGTCPVKVLPELPPV-----SPVSSTGPSETTGLTENPTISTKKPTV 572

Query: 786  SVIPNDISSNAAILGGQPPNVTSNSGILGVQRPNVSSNSEILGVRPSNVSSSSGIIAAQP 845
            S+    +++    +  + P + +    +  ++P + S    +      + S    I  + 
Sbjct: 573  SIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEK 632

Query: 846  PNILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGLLGTQPPAGP 905
            P I +    +  + P++S     +    P  P       ++ P +P     + T+ P+ P
Sbjct: 633  PTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIP 692

Query: 906  QNLPPLSIPNQRMPTMPMLDIRPGLIPQAPGPRFPLIQPGIPPQRGIPPPSVLDSALHPP 965
               P +S+    + T      +P + P+   P  P  +P IP ++    P   +    P 
Sbjct: 693  TEKPTISMEETIISTE-----KPTISPEK--PTIPTEKPTIPTEKSTISP---EKPTTPT 742

Query: 966  PRGPFPPGDIFSQPERPFLAPGRQSV--DNVTNPEKR--IPLGNDNIQQEGDRDYRFPPI 1021
             +   P       PE+P     + ++  + +T P ++  IP     I  E       P I
Sbjct: 743  EKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEK------PTI 796

Query: 1022 ETRESISRPPPVDVRDVVGRPIDPREGPGRP 1052
             T E  +  P  +      +P  P E P  P
Sbjct: 797  STEEPTT--PTEETTISTEKPSIPMEKPTLP 825



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 51/267 (19%), Positives = 98/267 (36%), Gaps = 24/267 (8%)

Query: 700 PVVPPPTIPPVVPTSLVQPS--LSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVF 757
           PV   P +PPV P S   PS    +T          ++ I   SV +   T       + 
Sbjct: 535 PVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTI- 593

Query: 758 NAPTKQAEPEEKVPHLIDHQISSGENTRSVIPND---ISSNAAILGGQPPNVTSNSGILG 814
             PT++     + P  I  +  +  + +  IP++   I +    +  + P + S    + 
Sbjct: 594 --PTEKPTISTEKP-TIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTIS 650

Query: 815 VQRPNVSSNSEILGVRPSNVSSSSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPP 874
            ++P V +         +  S    +I  + P+I      +  + P++S    ++    P
Sbjct: 651 TEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKP 710

Query: 875 NIPNNSGLVGVQPPNVPNTPGLLGTQPPAGPQNLPPLSIPNQR------MPTMPMLDIRP 928
            I      +  + P +P     +  + P  P   P  +IP ++       PT P    +P
Sbjct: 711 TISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKP--TIPTEKPTISPEKPTTP--TEKP 766

Query: 929 GLIPQ-----APGPRFPLIQPGIPPQR 950
            + P+        P  P  +P IP ++
Sbjct: 767 TISPEKLTIPTEKPTIPTEKPTIPTEK 793



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 77/398 (19%), Positives = 127/398 (31%), Gaps = 90/398 (22%)

Query: 588 GMIDQETVNTEWETVKSSEPVKETVQTTQSPT-PVEKETVVTTQAEVFPPPVAMLQIPVA 646
           G+ +  T++T+  TV   +P      TT+ PT P EK T+ T +                
Sbjct: 558 GLTENPTISTKKPTVSIEKPSV----TTEKPTVPKEKPTIPTEK---------------- 597

Query: 647 PAVPTVSLVPPAFPVSMPVPPPGFSPIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPPPT 706
              PT+S   P  P   P  P     IP           S+ P      P  P     PT
Sbjct: 598 ---PTISTEKPTIPSEKPNMPSEKPTIP-----------SEKPTILTEKPTIPS--EKPT 641

Query: 707 IPPVVPTSLVQPSLSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEP 766
           IP   PT   +     T E            P     +++    +P         K + P
Sbjct: 642 IPSEKPTISTEKPTVPTEEPTT---------PTEETTTSMEEPVIPTEKPSIPTEKPSIP 692

Query: 767 EEKVPHLIDHQISSGENTRSVIPNDISSNAAILGGQPPNVTSNSGILGVQRPNVSSNSEI 826
            EK                      IS    I+  + P ++     +  ++P + +    
Sbjct: 693 TEKPT--------------------ISMEETIISTEKPTISPEKPTIPTEKPTIPTEKST 732

Query: 827 LGVRPSNVSSSSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQ 886
           +        +    I  + P I         + P++S     +    P IP     +  +
Sbjct: 733 ISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTE 792

Query: 887 PPNV----PNTP---GLLGTQPPAGPQNLPPL------------SIPNQRMPTMPMLDIR 927
            P +    P TP     + T+ P+ P   P L            +I  +++ T+PM   +
Sbjct: 793 KPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKL-TIPM--EK 849

Query: 928 PGLIPQAPGPRFPLIQPGIPPQRGIPPPSVLDSALHPP 965
           P +  +   P  P  +P I P++   P   L      P
Sbjct: 850 PTISTEK--PTIPTEKPTISPEKLTIPTEKLTIPTEKP 885


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 91/336 (27%), Positives = 122/336 (36%), Gaps = 70/336 (20%)

Query: 656 PPAFPVSMPVPPPGFSPIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPPPTIPPVVPTSL 715
           PP+ P   PVP PG    PP           +P    MPPP P     P +IPP VP+  
Sbjct: 143 PPSGPGRFPVPSPGHRSGPP-----------EPQRNRMPPPRPDVGSKPDSIPPPVPS-- 189

Query: 716 VQPSLSMTPETVKDV--GFGSLVIPGG-----------SVASNLATSALPAGNVFNAPTK 762
                  TP  ++      GS  +PGG               N  T AL  G++  +P  
Sbjct: 190 -------TPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGT-ALGGGSIRQSPLS 241

Query: 763 QAEPEEKVPHLIDHQISSGENTRSVIPNDISSNAAI---LGGQPPNVTSNSGILGVQRPN 819
            + P    P L      + ++     P  + +  +I       PP   +   +    RP+
Sbjct: 242 SSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPS 301

Query: 820 VSSNSEILGVRPSNVS------SSSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLGVLP 873
            SS +      PS         SSSG    + P +   +  L    P +  S G  G LP
Sbjct: 302 ASSQAPPPPPPPSRPGPPPLPPSSSG--NDETPRLPQRNLSLSSSTPPLP-SPGRSGPLP 358

Query: 874 PNIPNNSGLVGVQPPNVPNTPGLLGTQPPAGPQNLPPLS---IPNQRMPTMPMLDIRPGL 930
           P            PP V + PG  G  PP      PP+S     ++ +P  P L  R G+
Sbjct: 359 PPPSER------PPPPVRDPPGRSGPLPPP-----PPVSRNGSTSRALPATPQLPSRSGV 407

Query: 931 IPQAPGPRFPLIQPGIPPQRGIPPPSVLDSALHPPP 966
                GPR PL  P   P  G PPP        PPP
Sbjct: 408 DSPRSGPRPPL--PPDRPSAGAPPP--------PPP 433



 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 61/226 (26%), Positives = 77/226 (34%), Gaps = 34/226 (15%)

Query: 864  NSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGLLGTQPPAGPQNLPPLSIPNQRMPTMPM 923
            N SG  G  PP +P        +P + P+ PG      P G ++ PP    N+  P  P 
Sbjct: 119  NDSG--GSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSP-GHRSGPPEPQRNRMPPPRPD 175

Query: 924  LDIRPGLIPQAPGPRFPLIQPGIPPQRGIPPPSVLDSALHPPPRGPFPP----------- 972
            +  +P  IP  P P  P      P  RG PP   +      P  GP PP           
Sbjct: 176  VGSKPDSIPP-PVPSTPRPIQSSPHNRGSPP---VPGGPRQPSPGPTPPPFPGNRGTALG 231

Query: 973  -GDIFSQP--------ERPFLAPGRQSVDNVTNPEKRIPLGN-DNIQQEGDRDYRFPPIE 1022
             G I   P         RP L P      +   P    P+GN  +I +E       PP  
Sbjct: 232  GGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPP--PPQN 289

Query: 1023 TRESISRPPPVDVRDVVGRPIDPREGPGRPPL----DGRDHFGRPP 1064
             +  +   P          P  P   PG PPL     G D   R P
Sbjct: 290  NKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLP 335



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 29/108 (26%), Positives = 44/108 (40%)

Query: 619 TPVEKETVVTTQAEVFPPPVAMLQIPVAPAVPTVSLVPPAFPVSMPVPPPGFSPIPPPPF 678
           +P+   +  + +  + P P   L     P  P V   P     ++P PPP  +  P P  
Sbjct: 238 SPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPST 297

Query: 679 LRASFNPSQPPPGFMPPPVPPPVVPPPTIPPVVPTSLVQPSLSMTPET 726
            R S +   PPP   P    PP +PP +        L Q +LS++  T
Sbjct: 298 PRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSST 345



 Score = 41.2 bits (95), Expect = 0.006
 Identities = 60/184 (32%), Positives = 70/184 (38%), Gaps = 36/184 (19%)

Query: 888  PNVPNTPGLLGTQPPAGPQNLPPL--SIPNQRMPTMP-----MLDIRPGLIPQAPGPRFP 940
            P  P  PG  GT    G     PL  S P    P +P      LD +P   P   G R P
Sbjct: 217  PTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNR-P 275

Query: 941  LIQ----PGIPPQRGIPP----PSVLDSALHPPPRGPFPPGDIFSQPERPFLAPGRQSVD 992
             I     P  PPQ   PP    P    S+  PPP  P PP    S+P  P L P     D
Sbjct: 276  SIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPP--PPPP----SRPGPPPLPPSSSGND 329

Query: 993  NVTN-PEKRIPLGNDN--IQQEGDRDYRFPPIETRESISRPPPVDVRDVVGRPIDPREGP 1049
                 P++ + L +    +   G R    PP  +     RPPP  VRD  G     R GP
Sbjct: 330  ETPRLPQRNLSLSSSTPPLPSPG-RSGPLPPPPS----ERPPP-PVRDPPG-----RSGP 378

Query: 1050 GRPP 1053
              PP
Sbjct: 379  LPPP 382



 Score = 40.8 bits (94), Expect = 0.008
 Identities = 38/121 (31%), Positives = 45/121 (37%), Gaps = 26/121 (21%)

Query: 618 PTPVEKETVVTTQAEVFPPPVAMLQIPVAPAVPTVSLV--------PPAFPVSMPVPP-- 667
           P PV     +    E  PPP      P  P+ P  S          PP+ P   P+PP  
Sbjct: 268 PPPVGNRPSI--HREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSS 325

Query: 668 PGFSPIPPPPFLRASFNPSQPP------PGFMPPP----VPPPVVPPP----TIPPVVPT 713
            G    P  P    S + S PP       G +PPP     PPPV  PP     +PP  P 
Sbjct: 326 SGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPV 385

Query: 714 S 714
           S
Sbjct: 386 S 386



 Score = 33.5 bits (75), Expect = 1.3
 Identities = 29/90 (32%), Positives = 35/90 (38%), Gaps = 5/90 (5%)

Query: 1028 SRPP--PVDVRDVVGRPIDPREGPGRPPLDGRDHFGRPPVDIRENLVRPGIDHLGRRDHF 1085
            SRPP  P   R    +P  P  GPGR P+    H   PP   R  +  P  D   + D  
Sbjct: 124  SRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPD-- 181

Query: 1086 GFNPEKPWGHRGDFDEREHR-VLPVYGGPK 1114
               P  P   R       +R   PV GGP+
Sbjct: 182  SIPPPVPSTPRPIQSSPHNRGSPPVPGGPR 211


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 91/336 (27%), Positives = 122/336 (36%), Gaps = 70/336 (20%)

Query: 656 PPAFPVSMPVPPPGFSPIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPPPTIPPVVPTSL 715
           PP+ P   PVP PG    PP           +P    MPPP P     P +IPP VP+  
Sbjct: 143 PPSGPGRFPVPSPGHRSGPP-----------EPQRNRMPPPRPDVGSKPDSIPPPVPS-- 189

Query: 716 VQPSLSMTPETVKDV--GFGSLVIPGG-----------SVASNLATSALPAGNVFNAPTK 762
                  TP  ++      GS  +PGG               N  T AL  G++  +P  
Sbjct: 190 -------TPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGT-ALGGGSIRQSPLS 241

Query: 763 QAEPEEKVPHLIDHQISSGENTRSVIPNDISSNAAI---LGGQPPNVTSNSGILGVQRPN 819
            + P    P L      + ++     P  + +  +I       PP   +   +    RP+
Sbjct: 242 SSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPS 301

Query: 820 VSSNSEILGVRPSNVS------SSSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLGVLP 873
            SS +      PS         SSSG    + P +   +  L    P +  S G  G LP
Sbjct: 302 ASSQAPPPPPPPSRPGPPPLPPSSSG--NDETPRLPQRNLSLSSSTPPLP-SPGRSGPLP 358

Query: 874 PNIPNNSGLVGVQPPNVPNTPGLLGTQPPAGPQNLPPLS---IPNQRMPTMPMLDIRPGL 930
           P            PP V + PG  G  PP      PP+S     ++ +P  P L  R G+
Sbjct: 359 PPPSER------PPPPVRDPPGRSGPLPPP-----PPVSRNGSTSRALPATPQLPSRSGV 407

Query: 931 IPQAPGPRFPLIQPGIPPQRGIPPPSVLDSALHPPP 966
                GPR PL  P   P  G PPP        PPP
Sbjct: 408 DSPRSGPRPPL--PPDRPSAGAPPP--------PPP 433



 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 61/226 (26%), Positives = 77/226 (34%), Gaps = 34/226 (15%)

Query: 864  NSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGLLGTQPPAGPQNLPPLSIPNQRMPTMPM 923
            N SG  G  PP +P        +P + P+ PG      P G ++ PP    N+  P  P 
Sbjct: 119  NDSG--GSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSP-GHRSGPPEPQRNRMPPPRPD 175

Query: 924  LDIRPGLIPQAPGPRFPLIQPGIPPQRGIPPPSVLDSALHPPPRGPFPP----------- 972
            +  +P  IP  P P  P      P  RG PP   +      P  GP PP           
Sbjct: 176  VGSKPDSIPP-PVPSTPRPIQSSPHNRGSPP---VPGGPRQPSPGPTPPPFPGNRGTALG 231

Query: 973  -GDIFSQP--------ERPFLAPGRQSVDNVTNPEKRIPLGN-DNIQQEGDRDYRFPPIE 1022
             G I   P         RP L P      +   P    P+GN  +I +E       PP  
Sbjct: 232  GGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPP--PPQN 289

Query: 1023 TRESISRPPPVDVRDVVGRPIDPREGPGRPPL----DGRDHFGRPP 1064
             +  +   P          P  P   PG PPL     G D   R P
Sbjct: 290  NKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLP 335



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 29/108 (26%), Positives = 44/108 (40%)

Query: 619 TPVEKETVVTTQAEVFPPPVAMLQIPVAPAVPTVSLVPPAFPVSMPVPPPGFSPIPPPPF 678
           +P+   +  + +  + P P   L     P  P V   P     ++P PPP  +  P P  
Sbjct: 238 SPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPST 297

Query: 679 LRASFNPSQPPPGFMPPPVPPPVVPPPTIPPVVPTSLVQPSLSMTPET 726
            R S +   PPP   P    PP +PP +        L Q +LS++  T
Sbjct: 298 PRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSST 345



 Score = 41.2 bits (95), Expect = 0.006
 Identities = 60/184 (32%), Positives = 70/184 (38%), Gaps = 36/184 (19%)

Query: 888  PNVPNTPGLLGTQPPAGPQNLPPL--SIPNQRMPTMP-----MLDIRPGLIPQAPGPRFP 940
            P  P  PG  GT    G     PL  S P    P +P      LD +P   P   G R P
Sbjct: 217  PTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNR-P 275

Query: 941  LIQ----PGIPPQRGIPP----PSVLDSALHPPPRGPFPPGDIFSQPERPFLAPGRQSVD 992
             I     P  PPQ   PP    P    S+  PPP  P PP    S+P  P L P     D
Sbjct: 276  SIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPP--PPPP----SRPGPPPLPPSSSGND 329

Query: 993  NVTN-PEKRIPLGNDN--IQQEGDRDYRFPPIETRESISRPPPVDVRDVVGRPIDPREGP 1049
                 P++ + L +    +   G R    PP  +     RPPP  VRD  G     R GP
Sbjct: 330  ETPRLPQRNLSLSSSTPPLPSPG-RSGPLPPPPS----ERPPP-PVRDPPG-----RSGP 378

Query: 1050 GRPP 1053
              PP
Sbjct: 379  LPPP 382



 Score = 40.8 bits (94), Expect = 0.008
 Identities = 38/121 (31%), Positives = 45/121 (37%), Gaps = 26/121 (21%)

Query: 618 PTPVEKETVVTTQAEVFPPPVAMLQIPVAPAVPTVSLV--------PPAFPVSMPVPP-- 667
           P PV     +    E  PPP      P  P+ P  S          PP+ P   P+PP  
Sbjct: 268 PPPVGNRPSI--HREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSS 325

Query: 668 PGFSPIPPPPFLRASFNPSQPP------PGFMPPP----VPPPVVPPP----TIPPVVPT 713
            G    P  P    S + S PP       G +PPP     PPPV  PP     +PP  P 
Sbjct: 326 SGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPV 385

Query: 714 S 714
           S
Sbjct: 386 S 386



 Score = 33.5 bits (75), Expect = 1.3
 Identities = 29/90 (32%), Positives = 35/90 (38%), Gaps = 5/90 (5%)

Query: 1028 SRPP--PVDVRDVVGRPIDPREGPGRPPLDGRDHFGRPPVDIRENLVRPGIDHLGRRDHF 1085
            SRPP  P   R    +P  P  GPGR P+    H   PP   R  +  P  D   + D  
Sbjct: 124  SRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPD-- 181

Query: 1086 GFNPEKPWGHRGDFDEREHR-VLPVYGGPK 1114
               P  P   R       +R   PV GGP+
Sbjct: 182  SIPPPVPSTPRPIQSSPHNRGSPPVPGGPR 211


>gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo
           sapiens]
          Length = 375

 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 46/114 (40%), Positives = 65/114 (57%), Gaps = 9/114 (7%)

Query: 350 SSQQHFLEPEVNLDDSIDIQQQDMDIDEGQDGVEEEVFEQEAKKVAVRSRSRTHSRSRSR 409
           SS++H  E   + + S D  ++ ++  E  +       ++  +K    SR R+HSRSRSR
Sbjct: 20  SSKKHKSEEHNDKEHSSDKGRERLNSSENGE-------DRHKRKERKSSRGRSHSRSRSR 72

Query: 410 SPRKR-RSRSRSGSRKR-KHRKRSRSRSRERKRKSSRSYSSERRAREREKERQK 461
             R R RSR R  SR R + RK+SRSRSRERK+  SRS   +RR R R + R +
Sbjct: 73  ERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSR 126



 Score = 66.6 bits (161), Expect = 1e-10
 Identities = 41/78 (52%), Positives = 52/78 (66%), Gaps = 6/78 (7%)

Query: 397 RSRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRKRSRSRSRERKRKSSRSYSSERRARERE 456
           RSRSR   +SRSRS  +++SRSRS  RKR+ R RSRSRSR R R  SRS     R R R 
Sbjct: 87  RSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRS-----RTRSRS 141

Query: 457 KERQKKGLPPIR-SKTLS 473
           ++R+K+   P R S++LS
Sbjct: 142 RDRKKRIEKPRRFSRSLS 159



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 37/73 (50%), Positives = 46/73 (63%), Gaps = 3/73 (4%)

Query: 389 QEAKKVAVRSRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRKRSRSRSRERKRKSSRSYSS 448
           +E KK   RSR R  SRSRSR  +K RSRSR   R+ + R RSRSR R R R  SR+ S 
Sbjct: 81  RERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRS- 139

Query: 449 ERRAREREKERQK 461
             R+R+R+K  +K
Sbjct: 140 --RSRDRKKRIEK 150



 Score = 60.8 bits (146), Expect = 8e-09
 Identities = 40/86 (46%), Positives = 47/86 (54%), Gaps = 2/86 (2%)

Query: 389 QEAKKVAVRSRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRKRSRSRSRERKRKSSRSYSS 448
           +E KK   RSR R  SRSRSR  RKRR RSRS SR R HR R+RSRSR R R   R    
Sbjct: 91  RERKKSRSRSRERKKSRSRSRE-RKRRIRSRSRSRSR-HRHRTRSRSRTRSRSRDRKKRI 148

Query: 449 ERRAREREKERQKKGLPPIRSKTLSV 474
           E+  R      +    PP R +  ++
Sbjct: 149 EKPRRFSRSLSRTPSPPPFRGRNTAM 174



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 36/89 (40%), Positives = 44/89 (49%), Gaps = 15/89 (16%)

Query: 389 QEAKKVAVRSRSR-----THSRSRSRSPRKRRSRSRSGSRKRKHRKR-------SRSRSR 436
           +E KK   RSR R     + SRSRSR   + RSRSR+ SR R  +KR       SRS SR
Sbjct: 101 RERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSR 160

Query: 437 ERKRKSSRSYSSERRARE---REKERQKK 462
                  R  ++   A+E   R  ER KK
Sbjct: 161 TPSPPPFRGRNTAMDAQEALARRLERAKK 189



 Score = 32.7 bits (73), Expect = 2.3
 Identities = 35/138 (25%), Positives = 63/138 (45%), Gaps = 18/138 (13%)

Query: 175 PDPWVSQITNTDTLAAVAQILQSPQGQQLQQLIQTLQIQQQKPQPSILQALDAGLVVQLQ 234
           P P+  + T  D   A+A+ L+  + ++LQ+  +   +++QK Q     A   G V+ + 
Sbjct: 164 PPPFRGRNTAMDAQEALARRLE--RAKKLQEQREKEMVEKQKQQEIAAAAATGGSVLNVA 221

Query: 235 ALTA---QLTAAAAAANTLTPL------EQGVS----FNKKLMDRFDFGEDSEHSE---E 278
           AL A   Q+T   A A  +  L      E G++    +N   ++   F E  +  +   +
Sbjct: 222 ALLASGTQVTPQIAMAAQMAALQAKALAETGIAVPSYYNPAAVNPMKFAEQEKKRKMLWQ 281

Query: 279 PKKEIPASQLSHVSESVN 296
            KKE   SQ + + E +N
Sbjct: 282 GKKEGDKSQSAEIWEKLN 299



 Score = 31.6 bits (70), Expect = 5.0
 Identities = 22/73 (30%), Positives = 36/73 (49%), Gaps = 10/73 (13%)

Query: 393 KVAVRSRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRKRSRSRSRERKRKS----SRSYSS 448
           K + + +S  H+     S + R   + S + + +H+++ R  SR          SRS S 
Sbjct: 19  KSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSR------GRSHSRSRSR 72

Query: 449 ERRAREREKERQK 461
           ERR R R +ER+K
Sbjct: 73  ERRHRSRSRERKK 85


>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
           sapiens]
          Length = 434

 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 46/114 (40%), Positives = 65/114 (57%), Gaps = 9/114 (7%)

Query: 350 SSQQHFLEPEVNLDDSIDIQQQDMDIDEGQDGVEEEVFEQEAKKVAVRSRSRTHSRSRSR 409
           SS++H  E   + + S D  ++ ++  E  +       ++  +K    SR R+HSRSRSR
Sbjct: 79  SSKKHKSEEHNDKEHSSDKGRERLNSSENGE-------DRHKRKERKSSRGRSHSRSRSR 131

Query: 410 SPRKR-RSRSRSGSRKR-KHRKRSRSRSRERKRKSSRSYSSERRAREREKERQK 461
             R R RSR R  SR R + RK+SRSRSRERK+  SRS   +RR R R + R +
Sbjct: 132 ERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSR 185



 Score = 66.6 bits (161), Expect = 1e-10
 Identities = 41/78 (52%), Positives = 52/78 (66%), Gaps = 6/78 (7%)

Query: 397 RSRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRKRSRSRSRERKRKSSRSYSSERRARERE 456
           RSRSR   +SRSRS  +++SRSRS  RKR+ R RSRSRSR R R  SRS     R R R 
Sbjct: 146 RSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRS-----RTRSRS 200

Query: 457 KERQKKGLPPIR-SKTLS 473
           ++R+K+   P R S++LS
Sbjct: 201 RDRKKRIEKPRRFSRSLS 218



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 37/73 (50%), Positives = 46/73 (63%), Gaps = 3/73 (4%)

Query: 389 QEAKKVAVRSRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRKRSRSRSRERKRKSSRSYSS 448
           +E KK   RSR R  SRSRSR  +K RSRSR   R+ + R RSRSR R R R  SR+ S 
Sbjct: 140 RERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRS- 198

Query: 449 ERRAREREKERQK 461
             R+R+R+K  +K
Sbjct: 199 --RSRDRKKRIEK 209



 Score = 60.8 bits (146), Expect = 8e-09
 Identities = 40/86 (46%), Positives = 47/86 (54%), Gaps = 2/86 (2%)

Query: 389 QEAKKVAVRSRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRKRSRSRSRERKRKSSRSYSS 448
           +E KK   RSR R  SRSRSR  RKRR RSRS SR R HR R+RSRSR R R   R    
Sbjct: 150 RERKKSRSRSRERKKSRSRSRE-RKRRIRSRSRSRSR-HRHRTRSRSRTRSRSRDRKKRI 207

Query: 449 ERRAREREKERQKKGLPPIRSKTLSV 474
           E+  R      +    PP R +  ++
Sbjct: 208 EKPRRFSRSLSRTPSPPPFRGRNTAM 233



 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 28/73 (38%), Positives = 41/73 (56%), Gaps = 5/73 (6%)

Query: 388 EQEAKKVAVRSRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRKRSRSRSRERKRKSSRSYS 447
           EQ    V+ R+    +SRSRSRS  ++R     G   RKH  RSRSRS+E +R  S+  S
Sbjct: 25  EQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEG---RKH--RSRSRSKEGRRHESKDKS 79

Query: 448 SERRAREREKERQ 460
           S++   E   +++
Sbjct: 80  SKKHKSEEHNDKE 92



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 38/136 (27%), Positives = 58/136 (42%), Gaps = 38/136 (27%)

Query: 364 DSIDIQQQDMDIDEGQDGVEEEVFEQEAKKVAVRSRSRTHSRSRSRSPRKRRSRSRSGSR 423
           D +  ++   D D+ ++  E  V  + +K    RSRSR+  R R      R+ RSRS S+
Sbjct: 9   DGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSK 68

Query: 424 K-RKHRKRSRS-------------------------------RSRERKRKS------SRS 445
           + R+H  + +S                               R + ++RKS      SRS
Sbjct: 69  EGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRS 128

Query: 446 YSSERRAREREKERQK 461
            S ERR R R +ER+K
Sbjct: 129 RSRERRHRSRSRERKK 144



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 36/89 (40%), Positives = 44/89 (49%), Gaps = 15/89 (16%)

Query: 389 QEAKKVAVRSRSR-----THSRSRSRSPRKRRSRSRSGSRKRKHRKR-------SRSRSR 436
           +E KK   RSR R     + SRSRSR   + RSRSR+ SR R  +KR       SRS SR
Sbjct: 160 RERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSR 219

Query: 437 ERKRKSSRSYSSERRARE---REKERQKK 462
                  R  ++   A+E   R  ER KK
Sbjct: 220 TPSPPPFRGRNTAMDAQEALARRLERAKK 248



 Score = 40.8 bits (94), Expect = 0.008
 Identities = 29/66 (43%), Positives = 33/66 (50%), Gaps = 9/66 (13%)

Query: 406 SRSRSPRKRRSRSRSGSRKRKHR-KRSRSRSRERKRKS--------SRSYSSERRARERE 456
           S  R  +K +S      R  KH   RSRSRSRERKRKS        SRS S E R  E +
Sbjct: 17  SPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESK 76

Query: 457 KERQKK 462
            +  KK
Sbjct: 77  DKSSKK 82



 Score = 32.7 bits (73), Expect = 2.3
 Identities = 35/138 (25%), Positives = 63/138 (45%), Gaps = 18/138 (13%)

Query: 175 PDPWVSQITNTDTLAAVAQILQSPQGQQLQQLIQTLQIQQQKPQPSILQALDAGLVVQLQ 234
           P P+  + T  D   A+A+ L+  + ++LQ+  +   +++QK Q     A   G V+ + 
Sbjct: 223 PPPFRGRNTAMDAQEALARRLE--RAKKLQEQREKEMVEKQKQQEIAAAAATGGSVLNVA 280

Query: 235 ALTA---QLTAAAAAANTLTPL------EQGVS----FNKKLMDRFDFGEDSEHSE---E 278
           AL A   Q+T   A A  +  L      E G++    +N   ++   F E  +  +   +
Sbjct: 281 ALLASGTQVTPQIAMAAQMAALQAKALAETGIAVPSYYNPAAVNPMKFAEQEKKRKMLWQ 340

Query: 279 PKKEIPASQLSHVSESVN 296
            KKE   SQ + + E +N
Sbjct: 341 GKKEGDKSQSAEIWEKLN 358


>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
          Length = 494

 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 39/63 (61%), Positives = 43/63 (68%), Gaps = 1/63 (1%)

Query: 398 SRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRK-RSRSRSRERKRKSSRSYSSERRARERE 456
           SRSR+HSRSRSRS   R+SRSRSGS K  H K RSRSRS  R R  SRS S  R   ++E
Sbjct: 186 SRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKE 245

Query: 457 KER 459
           K R
Sbjct: 246 KSR 248



 Score = 54.7 bits (130), Expect = 6e-07
 Identities = 32/74 (43%), Positives = 45/74 (60%), Gaps = 1/74 (1%)

Query: 397 RSRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRKRSRSRSRERKRKSSRSYS-SERRARER 455
           +SRSR+ S SRSRS  + RS+SRS S+K K R  S+ +SR R   + +S S S+ +A E+
Sbjct: 217 KSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEK 276

Query: 456 EKERQKKGLPPIRS 469
            +     G P  RS
Sbjct: 277 IQNNDNVGKPKSRS 290



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 49/193 (25%), Positives = 77/193 (39%), Gaps = 31/193 (16%)

Query: 274 EHSEEPKKEIPASQLSHVSESVNNSIFHQIAEQLQQQ-NLEHLRQQLLEQQQPQKATPQD 332
           E S  P KE   S+ SH +    +    Q  E++Q   N+   + +   + + +  +   
Sbjct: 245 EKSRSPSKEKSRSR-SHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSR 303

Query: 333 SQEGTFGSEHSASPSQGSSQQHFLEPEVNLDDSIDIQQQDMDIDEGQDGVEEEVFEQEAK 392
           SQE     E   S S+G SQ+  L             +Q       + G           
Sbjct: 304 SQERRVEEEKRGSVSRGRSQEKSL-------------RQSRSRSRSKGG----------- 339

Query: 393 KVAVRSRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRKRSRSRSRERKRKSSRSYSSERRA 452
                SRSR+ SRS+S+  RK R RSR  SR R   +    RSR+R  K      S ++ 
Sbjct: 340 -----SRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKK 394

Query: 453 REREKERQKKGLP 465
           ++ + +R +   P
Sbjct: 395 KKEDTDRSQSRSP 407



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 40/75 (53%), Positives = 45/75 (60%), Gaps = 11/75 (14%)

Query: 397 RSRSRTHSRSRSR------SPRKRRSRSRSGSRKR-KHRKRSRSRSRERKRKSSRSYSSE 449
           RSRSR   +SRSR      S  K RSRSRSGSR R K R RS+SRSR +K K SRS S E
Sbjct: 195 RSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEK-SRSPSKE 253

Query: 450 R---RAREREKERQK 461
           +   R+    K R K
Sbjct: 254 KSRSRSHSAGKSRSK 268



 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 38/141 (26%), Positives = 68/141 (48%), Gaps = 10/141 (7%)

Query: 308 QQQNLEHLRQQLLEQQQPQKATPQDSQEGTFGSEHSASPSQGSSQQHFLEPEVNLDDSID 367
           ++++    R +   ++  ++ + +DS+ G+   +      +  S+     P  ++    +
Sbjct: 361 REESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRS----PSRSVSKERE 416

Query: 368 IQQQDMDIDEGQDGVEEEVFEQEAKKVAVRSRSRTHSRSRSRSPRKRRSRSRSGSRKRKH 427
             + +    EG+   E     QE      RSRSR++S+S+   P + RSRS+S S+ R  
Sbjct: 417 HAKSESSQREGRGESENAGTNQET-----RSRSRSNSKSKPNLPSESRSRSKSASKTRSR 471

Query: 428 RK-RSRSRSRERKRKSSRSYS 447
            K RSRS SR   R  SRS+S
Sbjct: 472 SKSRSRSASRSPSRSRSRSHS 492



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 31/95 (32%), Positives = 43/95 (45%), Gaps = 12/95 (12%)

Query: 391 AKKVAVRSRSRTHSRSRSRSPRKRRSRSRS------------GSRKRKHRKRSRSRSRER 438
           +KK   RS S+  SRSRS S  K RS+S+             G  K +   R +S+S+ R
Sbjct: 242 SKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSR 301

Query: 439 KRKSSRSYSSERRAREREKERQKKGLPPIRSKTLS 473
            R   R    E+R        Q+K L   RS++ S
Sbjct: 302 SRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRS 336



 Score = 41.2 bits (95), Expect = 0.006
 Identities = 29/78 (37%), Positives = 41/78 (52%), Gaps = 16/78 (20%)

Query: 412 RKRRSRSRSGSRKR-----KHRKRSRSR----------SRERKRKSSRSYSSER-RARER 455
           R+RRS SRS S  R     +H ++SRSR          SR R R  SRS S  R R++ R
Sbjct: 180 RRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSR 239

Query: 456 EKERQKKGLPPIRSKTLS 473
            + +++K   P + K+ S
Sbjct: 240 SRSKKEKSRSPSKEKSRS 257



 Score = 38.9 bits (89), Expect = 0.032
 Identities = 29/99 (29%), Positives = 46/99 (46%), Gaps = 8/99 (8%)

Query: 369 QQQDMDIDEGQDGVEEEVFEQEAKKVAVRSRSRTHSRSRSRSPRKRRSRSRSGSRKR--- 425
           +++D D  + +        E+E  K     R        + + ++ RSRSRS S+ +   
Sbjct: 395 KKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNL 454

Query: 426 --KHRKRSRSRSRERKRKSSRSYSSER---RAREREKER 459
             + R RS+S S+ R R  SRS S+ R   R+R R   R
Sbjct: 455 PSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSR 493



 Score = 35.4 bits (80), Expect = 0.35
 Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 3/82 (3%)

Query: 341 EHSASPSQGSSQQHFLEPEVNLDDSIDIQQQDMDIDEGQDGVEEEVFEQEAKKVAVRSRS 400
           EH+ S S   SQ+       N   + + + +     + +  +  E   +       RSRS
Sbjct: 416 EHAKSES---SQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRS 472

Query: 401 RTHSRSRSRSPRKRRSRSRSGS 422
           ++ SRS SRSP + RSRS S S
Sbjct: 473 KSRSRSASRSPSRSRSRSHSRS 494



 Score = 32.7 bits (73), Expect = 2.3
 Identities = 20/55 (36%), Positives = 29/55 (52%), Gaps = 5/55 (9%)

Query: 414 RRSRSRSGSRKRKH--RKRSRSRSRERKRKSSRSYS---SERRAREREKERQKKG 463
           R    + GSR+R+   R RS SRSR R R S +S S   S + +  + + R + G
Sbjct: 171 RLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSG 225


>gi|14670268 RD RNA-binding protein [Homo sapiens]
          Length = 380

 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 73/269 (27%), Positives = 111/269 (41%), Gaps = 25/269 (9%)

Query: 276 SEEPKKEIPASQLSHVSESVNNSIFHQIAEQLQQQNLEHLRQQLLEQQQPQKATPQDSQE 335
           +E+ K+ + +  +S +     NS F         +    L  +L + ++    T Q  Q 
Sbjct: 62  TEQAKQLVKSGAISAIKAETKNSGF---------KRSRTLEGKLKDPEKGPVPTFQPFQR 112

Query: 336 GTFGSEHSASPSQGSSQQHFLEPEVNLDDSIDIQQQDMDIDEGQ---DGVEEEV-FEQEA 391
                +     S+   ++   E  V+  D +     D +  EG    DG      +  E 
Sbjct: 113 SISADDDLQESSRRPQRKSLYESFVSSSDRLRELGPDGEEAEGPGAGDGPPRSFDWGYEE 172

Query: 392 KKVAVRSRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRKRSRSRSRERKRKSSRSYSSER- 450
           +  A  S S   SRSR RS  + R R R   R R  R R R R R+R R   R    ER 
Sbjct: 173 RSGAHSSASPPRSRSRDRSHERNRDRDRDRERDRD-RDRDRDRERDRDRDRDRDRDRERD 231

Query: 451 RAREREKERQKKGLPPIR------SKTLSVCSTTLWVGQVDKKATQQDLTNLFEEFGQIE 504
           R RER+++R ++G  P R       +       TL+V   D   T   L   F  FG I 
Sbjct: 232 RDRERDRDRDREG--PFRRSDSFPERRAPRKGNTLYVYGEDMTPTL--LRGAFSPFGNII 287

Query: 505 SINMIPPRGCAYVCMVHRQDAFRALQKLS 533
            ++M PPR CA+V     + A +A+ +L+
Sbjct: 288 DLSMDPPRNCAFVTYEKMESADQAVAELN 316


>gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens]
          Length = 1711

 Score = 68.6 bits (166), Expect = 4e-11
 Identities = 87/381 (22%), Positives = 139/381 (36%), Gaps = 61/381 (16%)

Query: 618 PTPVEKETVVTTQAEVFPPPVAMLQIPVAPAVPTVSLVPPAFPVSMPVPPPGFSPIPPPP 677
           P P+           V  PP+A++Q PV P+ PT+ L         PVP P  +P+P   
Sbjct: 294 PVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLA--------PVPTPVLAPMP--- 342

Query: 678 FLRASFNPSQPPPGFMPPPVPPPVVPPPTIPPVVPTSLVQPSLSMTPETVKDVGFGSLVI 737
              AS  P+ P P  +P P P P   PP+ P ++P     P  + TP  +         +
Sbjct: 343 ---ASTPPAAPAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTP--APTPM 397

Query: 738 PGGSVASNLATSALPAGNVFNA---PTKQAEPEEKVPHLIDHQISSGENTRSVIPNDISS 794
           P  + A+   ++ +PA    +    P  QA   +KVP                       
Sbjct: 398 PAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVP----------------------- 434

Query: 795 NAAILGGQPPNVTSNSGILGVQRPNVSSNSEILGVRPSNVSSSSGIIAAQPPNILNNSGI 854
               L  QP  V + S  L    P        +   P+ +  SS +     P+ L +  +
Sbjct: 435 ----LSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCL 490

Query: 855 LGI-QPPSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGLLGTQPPAGPQNLP-PLS 912
            G+   P + +      V  P + ++S LV ++   +P T     T     P  +P PL+
Sbjct: 491 PGVLASPELRSYPYAFSVARP-LTSDSKLVSLEVNRLPCTSPSGSTTTQPAPDGVPGPLA 549

Query: 913 IPNQRMPTMPMLDIRPGLIPQAPG---PRFPLIQPGIPPQR---------GIPPPSVLDS 960
             +    +  +L     L+P   G   P  P   P    Q+          +  P  L+ 
Sbjct: 550 DTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSPLKSPPQLER 609

Query: 961 ALHPPPRGPFPPGDIFSQPER 981
            +  PP     P D+ S+  R
Sbjct: 610 EMASPPECSEMPLDLSSKSNR 630



 Score = 39.3 bits (90), Expect = 0.024
 Identities = 45/159 (28%), Positives = 63/159 (39%), Gaps = 16/159 (10%)

Query: 614 TTQSPTPVEKET-VVTTQAEVFPPPVAMLQIPVAPAVPTVS-LVPPAFPVSMPVPPPGFS 671
           T  +  PVE    +VTT     P P+     P AP   +V   VP AF V + VP    +
Sbjct: 178 TLGTGVPVEGTLPLVTTNFSPLPAPIC----PPAPGSASVPHSVPDAFQVPLSVP----A 229

Query: 672 PIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPPPTIPPVV----PTSLVQPSLSMTPETV 727
           P+P    +      S P P     PVP     PP++P ++    P S+    L   P + 
Sbjct: 230 PVPHSGLVPVQVATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASA 289

Query: 728 KDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEP 766
              G   L  P  +  S +  SA P   +  AP   + P
Sbjct: 290 PPSGPVPLSAPAPAPLS-VPVSAPPLA-LIQAPVPPSAP 326



 Score = 34.3 bits (77), Expect = 0.78
 Identities = 36/131 (27%), Positives = 57/131 (43%), Gaps = 17/131 (12%)

Query: 383  EEEVFEQEAKKVAVRSRSRTHSRSRSRSPRKRRSRS-RSGSRKRKHRKRSRSRSRERKRK 441
            EE+  + +AK V VRS  R   R     P++   +S R  S   K     R + + RK  
Sbjct: 1128 EEQQLQPQAKAV-VRSSHRPKCRKLPSDPQESTKKSPRGASDSGKEHNGVRGKHKHRKPT 1186

Query: 442  SSRSYSSERRAREREK---ERQKKG-----LPPI-----RSKTLSVCSTTLWVGQVDKKA 488
               S S  +RA   E+   E++ K      +P +     RS++ S+CS+  + G  D   
Sbjct: 1187 KPESQSPGKRADSHEEGSLEKKAKSSFRDFIPVVLSTRTRSQSGSICSS--FAGMADSDM 1244

Query: 489  TQQDLTNLFEE 499
              Q++    EE
Sbjct: 1245 GSQEVFPTEEE 1255



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 30/129 (23%), Positives = 56/129 (43%), Gaps = 16/129 (12%)

Query: 327  KATPQDSQEGTFGSEHSASPSQGSSQQHFLEPEVNLDDSIDIQQQDMDIDEGQDGVEEEV 386
            + T +D+Q   + S H+   S  S  +  L     +    +  +Q  D +E ++  EEE 
Sbjct: 1269 RKTQRDTQ---YRSHHAQDKSLLSQGRRHLWRAREMPWRTEAARQMWDTNEEEEEEEEEG 1325

Query: 387  FEQEAKKVAVRSRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRKRSRSRSRERKRKSSRSY 446
              +  K+             R +  RK ++      ++ + R++ R+  + RK+K+S S 
Sbjct: 1326 LLKRKKR-------------RRQKSRKYQTGEYLTEQEDEQRRKGRADLKARKQKTSSSQ 1372

Query: 447  SSERRARER 455
            S E R R R
Sbjct: 1373 SLEHRLRNR 1381



 Score = 31.6 bits (70), Expect = 5.0
 Identities = 49/173 (28%), Positives = 66/173 (38%), Gaps = 23/173 (13%)

Query: 828 GVRPSNVSSSSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQP 887
           G+ P  V++S  + A  PP  L     L   PPSV     L+    P   + S LV V  
Sbjct: 235 GLVPVQVATS--VPAPSPP--LAPVPALAPAPPSVPT---LISDSNPLSVSASVLVPVPA 287

Query: 888 PNVPNTPGLLGTQPPAG---PQNLPPLSIPNQRMP-TMPMLDIRP------GLIPQAPGP 937
              P+ P  L    PA    P + PPL++    +P + P L + P        +P +  P
Sbjct: 288 SAPPSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPP 347

Query: 938 RFPLIQPGIP-----PQRGIPPPSVLDSALHPPPRGPFPPGDIFSQPERPFLA 985
             P   P +P     P  G P    L  A  P P     P  IF+    P  A
Sbjct: 348 AAPA-PPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPA 399



 Score = 31.6 bits (70), Expect = 5.0
 Identities = 25/117 (21%), Positives = 49/117 (41%), Gaps = 22/117 (18%)

Query: 383  EEEVFEQEAKKVAVRSRSRT------HSRSRSRSPRKRRSRSRS---------------- 420
            EEEV    AK+  VR   R       H++ +S   + RR   R+                
Sbjct: 1255 EEEVTPTPAKRRKVRKTQRDTQYRSHHAQDKSLLSQGRRHLWRAREMPWRTEAARQMWDT 1314

Query: 421  GSRKRKHRKRSRSRSRERKRKSSRSYSSERRAREREKERQKKGLPPIRSKTLSVCST 477
               + +  +    + ++R+R+ SR Y +     E+E E+++KG   ++++     S+
Sbjct: 1315 NEEEEEEEEEGLLKRKKRRRQKSRKYQTGEYLTEQEDEQRRKGRADLKARKQKTSSS 1371


>gi|24307919 small nuclear ribonucleoprotein 27kDa (U4/U6.U5) [Homo
           sapiens]
          Length = 155

 Score = 67.4 bits (163), Expect = 8e-11
 Identities = 44/108 (40%), Positives = 62/108 (57%), Gaps = 6/108 (5%)

Query: 405 RSRSRSPRKRRSRSRSGSRKRKHRKRSRSRSRERKRKSSRSYSSERRAREREKERQKKGL 464
           RSRSRSPR+ R RSRS SR+R+ R+R RSRSRER R+ SRS S  RR R R   R +   
Sbjct: 3   RSRSRSPRRERRRSRSTSRERERRRRERSRSRERDRRRSRSRSPHRR-RSRSPRRHRSTS 61

Query: 465 PP---IRSKTLSVCSTTLWVGQVDKKATQQDLTNLFEEFGQIESINMI 509
           P    ++ +       T      +++ T++DL    EE  +IE + ++
Sbjct: 62  PSPSRLKERRDEEKKETKETKSKERQITEEDLEGKTEE--EIEMMKLM 107



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 31/72 (43%), Positives = 40/72 (55%), Gaps = 6/72 (8%)

Query: 397 RSRSRTHSRSRSRSPRKR-RSRSRSGSRKRK-----HRKRSRSRSRERKRKSSRSYSSER 450
           R R R+ S SR R  R+R RSRSR   R+R      HR+RSRS  R R    S S   ER
Sbjct: 11  RERRRSRSTSRERERRRRERSRSRERDRRRSRSRSPHRRRSRSPRRHRSTSPSPSRLKER 70

Query: 451 RAREREKERQKK 462
           R  E+++ ++ K
Sbjct: 71  RDEEKKETKETK 82



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 30/68 (44%), Positives = 38/68 (55%), Gaps = 11/68 (16%)

Query: 397 RSRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRKRSRSRSR------ERKRKSSRSYSSER 450
           RSR R   RSRSRSP +RRSRS      R+HR  S S SR      E K+++  + S ER
Sbjct: 32  RSRERDRRRSRSRSPHRRRSRS-----PRRHRSTSPSPSRLKERRDEEKKETKETKSKER 86

Query: 451 RAREREKE 458
           +  E + E
Sbjct: 87  QITEEDLE 94



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 24/66 (36%), Positives = 35/66 (53%)

Query: 397 RSRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRKRSRSRSRERKRKSSRSYSSERRARERE 456
           RSRSR+  R RSRSPR+ RS S S SR ++ R   +  ++E K K  +    +   +  E
Sbjct: 40  RSRSRSPHRRRSRSPRRHRSTSPSPSRLKERRDEEKKETKETKSKERQITEEDLEGKTEE 99

Query: 457 KERQKK 462
           +    K
Sbjct: 100 EIEMMK 105


>gi|146134388 YLP motif containing 1 [Homo sapiens]
          Length = 2146

 Score = 67.4 bits (163), Expect = 8e-11
 Identities = 69/245 (28%), Positives = 99/245 (40%), Gaps = 35/245 (14%)

Query: 635 PPPVAMLQIPVAPAVPTVSLVPPAFPVSMPVP-------PPGFSPIPPPPFLRASFNPSQ 687
           PPP+  +  PV P      ++PPA P ++P P       PP      PPP +  S + + 
Sbjct: 527 PPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAG 586

Query: 688 PPPGFMPPPV----PPPVVPPPTI-----PPVVPTSLVQPSLSMTPETVKDVGFGSLVIP 738
           PPP   PP +    PPPV+PPP++     PPV+P   + P  S TP      G     +P
Sbjct: 587 PPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMP---LPPLSSATPPP----GIPPPGVP 639

Query: 739 GGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDHQISSGENTRSVIPNDISSNAAI 798
            G      A    PA    ++      PE+  P L+   +S G    +     + S    
Sbjct: 640 QGIPPQLTAAPVPPA----SSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPLQS---- 691

Query: 799 LGGQPPNVTSNSGILGVQRPNVSSNSEILGVRPSNVSSSSGIIAAQPPNILNNSGILGIQ 858
             G    V S + +     P  SS S   G+  S+ + S  I A +   +   SG L   
Sbjct: 692 -AGPSEQVNSKAPLSKSALP-YSSFSSDQGLGESSAAPSQPITAVKDMPV--RSGGLLPD 747

Query: 859 PPSVS 863
           PP  S
Sbjct: 748 PPRSS 752



 Score = 63.9 bits (154), Expect = 9e-10
 Identities = 62/208 (29%), Positives = 81/208 (38%), Gaps = 44/208 (21%)

Query: 600 ETVKSSEPVKETVQTTQS-PTPVEKETVVTTQAEVFPPPVA--MLQIPVAP-----AVPT 651
           E V S + +K       S P P    + +       PPPV    L  PV P      VP 
Sbjct: 498 EKVNSFQNMKNQYMGNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPP 557

Query: 652 VSLVPPAFPVSMP--VPPPGFSP----------IPPPPFLRASFNPSQPPPGFM---PPP 696
             + PP  P S+P  VPPPG  P          +PPP    A   P  PPP      PPP
Sbjct: 558 PGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPP 617

Query: 697 V----------PPPVVPPPTIPPVVPTSL----VQPSLSMTPETVKDVGFGSLVIPGGSV 742
           V          PPP +PPP +P  +P  L    V P+ S     V +    +L+    S 
Sbjct: 618 VMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSF 677

Query: 743 ASNLATSALPAGNVFNAPTKQAEPEEKV 770
            S   T+       ++ P + A P E+V
Sbjct: 678 GSAPPTT-------YHPPLQSAGPSEQV 698



 Score = 60.8 bits (146), Expect = 8e-09
 Identities = 79/324 (24%), Positives = 124/324 (38%), Gaps = 27/324 (8%)

Query: 647 PAVPTVSLVPPAFPVSMPVPPPGFSPIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPPPT 706
           P VP   + PP   +  PV PP   P   PP L A+  P   PP  MPP +P   VPPP 
Sbjct: 519 PFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTS-VPPPG 577

Query: 707 IPPVVPTSLVQPSLSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEP 766
           +PP +  S   P   + P ++   G    V+P  S++S      +P   + +A      P
Sbjct: 578 MPPSL--SSAGPPPVLPPPSLSSAG-PPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIP 634

Query: 767 EEKVPHLIDHQISSGENTRSVIPNDISSNAAILGGQPPNVTSNSGILGVQRPNVSSNSEI 826
              VP  I  Q+     T + +P   SS ++ +  +P      + +     P  + +  +
Sbjct: 635 PPGVPQGIPPQL-----TAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPL 689

Query: 827 LGVRPSNVSSSSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQ 886
               PS   +S   ++       + S   G+   S + S  +  V   ++P  SG +   
Sbjct: 690 QSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPITAV--KDMPVRSGGL--- 744

Query: 887 PPNVPNTPGLLGTQPPAGPQNLPPLSIPNQRMPTMPMLDIRPGLIPQAPGPRFPLIQPGI 946
              +P+ P     + P GP+   P    +                P+  GPRF   +P  
Sbjct: 745 ---LPDPPRSSYLESPRGPRFDGPRRFEDLGSRCEG---------PRPKGPRFEGNRPDG 792

Query: 947 P-PQRGIPPPSVLDSALHPPPRGP 969
           P P+    P     S     PRGP
Sbjct: 793 PRPRYEGHPAEGTKSKWGMIPRGP 816



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 47/143 (32%), Positives = 57/143 (39%), Gaps = 21/143 (14%)

Query: 855 LGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGLLGTQPPAG---------- 904
           L   PP V   S    V+PP +P      G+ PP +P  P L  + PP G          
Sbjct: 530 LPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMP--PSLPTSVPPPGMPPSLSSAGP 587

Query: 905 PQNLPPLSIPNQRMPTMPMLDIRPGLIPQAPGPRFPL--IQPGIPPQRGIPPPSVLDSAL 962
           P  LPP S+ +   P  P+L   P L   AP P  PL  +    PP  GIPPP V     
Sbjct: 588 PPVLPPPSLSSAGPP--PVLP-PPSLSSTAPPPVMPLPPLSSATPPP-GIPPPGVPQGIP 643

Query: 963 HPPPRGPFPPGDIFSQ---PERP 982
                 P PP         PE+P
Sbjct: 644 PQLTAAPVPPASSSQSSQVPEKP 666



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 31/89 (34%), Positives = 37/89 (41%), Gaps = 32/89 (35%)

Query: 665 VPPPGFSPIPPPPFLRAS-FNPSQPPPGFMPPPV-----------------------PPP 700
           +PPP   P+PPPP +    +   QPPP  MPPP                        PP 
Sbjct: 81  LPPP---PLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPG 137

Query: 701 VVP-----PPTIPPVVPTSLVQPSLSMTP 724
           +VP     PP  PPV P S + PS S  P
Sbjct: 138 LVPMELESPPESPPVPPGSYMPPSQSYMP 166



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 22/57 (38%), Positives = 28/57 (49%), Gaps = 3/57 (5%)

Query: 654  LVPPAFPVSMPVP---PPGFSPIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPPPTI 707
            + PP      P P   PPG    P  P  R+S   ++PP    PPP PPP+ PPP +
Sbjct: 1505 MYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLPPPPPV 1561



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 39/122 (31%), Positives = 52/122 (42%), Gaps = 23/122 (18%)

Query: 887 PPNVPNTPGLLGT-----QPPAGPQNLPP---LSIPNQRMPTMPML----DIRPGLIP-- 932
           PP +P  P + G      QPP  P   PP   LS   Q+     ML    D  PGL+P  
Sbjct: 83  PPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVPME 142

Query: 933 -QAPGPRFPLIQPG--IPPQRGIPPPSVLDSALHPPPRG-----PFPPGDIFSQPERPFL 984
            ++P P  P + PG  +PP +   PP     + +PP        P  P    S P + +L
Sbjct: 143 LESP-PESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYL 201

Query: 985 AP 986
           AP
Sbjct: 202 AP 203



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 29/90 (32%), Positives = 36/90 (40%), Gaps = 16/90 (17%)

Query: 620  PVEKETVVTTQAEVFPPPVAMLQIPVAPAVPTVSLVPPAFPVSMPVPPPGFSPIPPPPFL 679
            P E     T+      PP    + P     P  S+V P+ P +    P    P+P PP  
Sbjct: 1491 PQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPP-- 1548

Query: 680  RASFNPSQPPPGFMPPPVPPPVVPPPTIPP 709
                    PPP   PPP+PP   PPP I P
Sbjct: 1549 --------PPP---PPPLPP---PPPVIKP 1564



 Score = 39.7 bits (91), Expect = 0.019
 Identities = 32/114 (28%), Positives = 48/114 (42%), Gaps = 20/114 (17%)

Query: 656 PPAFPVSMPVPPPGFSPIPPPPFLRASFN---PSQPPPGFMPPPVPPPVVPPPTIPPVVP 712
           P   P+ +  PP    P+PP  ++  S +   P QPPP + PP    P +PP        
Sbjct: 136 PGLVPMELESPPES-PPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPP-------- 186

Query: 713 TSLVQPSLSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEP 766
               QPS S +P +   +       P  S +S+ + S L     +  P+ QA P
Sbjct: 187 ---AQPSPSQSPPSQSYLA----PTPSYSSSSSSSQSYLSHSQSY-LPSSQASP 232



 Score = 39.7 bits (91), Expect = 0.019
 Identities = 98/388 (25%), Positives = 139/388 (35%), Gaps = 64/388 (16%)

Query: 902  PAGPQNLPPLSIPNQRMPTMPMLDIRPGLIPQAPG---PRFPLIQPGIPPQRGIPPPSVL 958
            P    +LPP     Q   + P +   PG     P    P   +++P  PP R   P +  
Sbjct: 1483 PQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRP 1542

Query: 959  DSALHPPPRGPFPPGDIFSQPERPFLAPGRQSVDNVT-NPEKRIPLGNDNIQQEGDRDYR 1017
               + PPP  P PP      P  P + P   +V+    + +    L + N +Q  + +++
Sbjct: 1543 PVPIPPPP--PPPP----LPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFK 1596

Query: 1018 -----------FPPIETRESISRPPPVDVRDVVGRPIDPREGPGRPPLDGRDHFGRPPVD 1066
                        PP     SI  P PV     +G P  P   P  PP+     +G    D
Sbjct: 1597 SETAAIPSAPVLPPPPVHSSIPPPGPVP----MGMP--PMSKP--PPVQQTVDYGHGR-D 1647

Query: 1067 IRENLVRPGIDHLGRRDHFGFNPEKPWGHRGDFDEREHRVLPVYGGPKGLHEERGRFRSG 1126
            I  N V    + +   +     P+ P   R  F E EH          G  +   R R  
Sbjct: 1648 ISTNKV----EQIPYGERITLRPD-PLPERSTF-ETEH---------AGQRDRYDRERDR 1692

Query: 1127 NYRFDPRSGPWNRGFGQEVHRDFD-DRRRPWERQRDRDDRDFDFCREMNGNRLGRDRIQN 1185
               FD +S           HRDF  DR    +R RDR   D+D  R     R   DR Q+
Sbjct: 1693 EPYFDRQSNV------IADHRDFKRDRETHRDRDRDRGVIDYDRDRFDRERRPRDDRAQS 1746

Query: 1186 TWVPPPHARV-FDYFEGATSQRKGDNVPQVNGENT---ERHAQPP---PIPVQNDPELYE 1238
                  H+      F+  +  RK D  P   G +    ER   P    P+P    P L  
Sbjct: 1747 YRDKKDHSSSRRGGFDRPSYDRKSDR-PVYEGPSMFGGERRTYPEERMPLPA---PSLSH 1802

Query: 1239 KLTSSNEINKE-KSDTVADIESEPVVES 1265
            +   +  + K+ +S  V DI   P  ES
Sbjct: 1803 QPPPAPRVEKKPESKNVDDILKPPGRES 1830



 Score = 39.3 bits (90), Expect = 0.024
 Identities = 32/128 (25%), Positives = 46/128 (35%), Gaps = 35/128 (27%)

Query: 636  PPVAMLQIPVAPAVPTVSLVPPAFPVSMPVPPPGFSPIPPPP------------------ 677
            PP ++++    PA  +V +  P  P+  P PPP   P+PPPP                  
Sbjct: 1521 PPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPP---PLPPPPPVIKPQTSAVEQERWDED 1577

Query: 678  ------------FLRASFNPSQPPPGFMPPPVPPPVVPPPTIPPVVPTSLVQPSLSMTPE 725
                         L + F          P   PPPV    +IPP  P  +  P +S  P 
Sbjct: 1578 SFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPV--HSSIPPPGPVPMGMPPMSKPPP 1635

Query: 726  TVKDVGFG 733
              + V +G
Sbjct: 1636 VQQTVDYG 1643



 Score = 38.9 bits (89), Expect = 0.032
 Identities = 31/100 (31%), Positives = 41/100 (41%), Gaps = 21/100 (21%)

Query: 904 GPQNLPPLSIPNQRMP----TMPMLDIRPGLIPQAPGPRFPLIQPGIPPQRGIPPPSV-- 957
           G  ++PP  +P  +MP    TMP     P L P  P P  P   P   P  G+PPP +  
Sbjct: 512 GNMSMPPPFVPYSQMPPPLPTMPP----PVLPPSLPPPVMPPALPATVPPPGMPPPVMPP 567

Query: 958 -LDSALHPPPRGP----------FPPGDIFSQPERPFLAP 986
            L +++ PP   P           PP  + S    P L P
Sbjct: 568 SLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPP 607



 Score = 38.1 bits (87), Expect = 0.054
 Identities = 36/151 (23%), Positives = 57/151 (37%), Gaps = 18/151 (11%)

Query: 637 PVAMLQIPVAPAVPTVSLVPPAFPVSMPVPPPGFSPIPPPPFLRASFNPSQPPPGFMPPP 696
           P+ +   P +P VP  S +PP    S    PP   P PPP     S+ P      ++PP 
Sbjct: 140 PMELESPPESPPVPPGSYMPP----SQSYMPP---PQPPP-----SYYPPTSSQPYLPPA 187

Query: 697 VPPPVVPPPTIPPVVPTSLVQPSLSMTPETVKD-VGFGSLVIPGGSVASNLATSALPAGN 755
            P P   PP+   + PT    PS S +  + +  +      +P    + +  +       
Sbjct: 188 QPSPSQSPPSQSYLAPT----PSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQ 243

Query: 756 VFNAPTKQAEPEEKVPHLIDHQISSGENTRS 786
           +   P   A P  K   +    + SG   +S
Sbjct: 244 LLAPPPPSAPPGNKTT-VQQEPLESGAKNKS 273



 Score = 36.6 bits (83), Expect = 0.16
 Identities = 25/64 (39%), Positives = 32/64 (50%), Gaps = 11/64 (17%)

Query: 666  PPPGFSPIPPPPF-------LRASFNPSQPPPGFMPPPVPPP-VVPPPTIPPVVPTSLVQ 717
            PPPG S  PPPP        +R S  P++       PPVP P   PPP +PP  P  +++
Sbjct: 1507 PPPG-SYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLPP--PPPVIK 1563

Query: 718  PSLS 721
            P  S
Sbjct: 1564 PQTS 1567



 Score = 35.0 bits (79), Expect = 0.46
 Identities = 26/95 (27%), Positives = 42/95 (44%), Gaps = 13/95 (13%)

Query: 128 IQPLLDMAAGIPPPVVTPVLASTTTAMSNTPGTPVTPVTPANVVQGLPDPWVSQITNTDT 187
           + P   +++  PPPV+ P   S+T   +  P  P+ P++ A    G+P P V Q      
Sbjct: 590 VLPPPSLSSAGPPPVLPPPSLSST---APPPVMPLPPLSSATPPPGIPPPGVPQGIPPQL 646

Query: 188 LAAVAQILQSPQGQQLQQLIQTLQIQQQKPQPSIL 222
            AA      S Q  Q+           +KP+P++L
Sbjct: 647 TAAPVPPASSSQSSQV----------PEKPRPALL 671



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 31/108 (28%), Positives = 44/108 (40%), Gaps = 12/108 (11%)

Query: 600 ETVKSSEPVKETVQTTQSP-------TPVEKETVVTTQAEVFPPPVAMLQIPVAPAVPTV 652
           E ++S    K T Q   +P       TP E++     Q  +       + +P     P V
Sbjct: 263 EPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVV 322

Query: 653 SLVPPAFPVSMPVPPPGFSPIPPPPFLRASFNPSQPPPG-FMPPPVPP 699
           +   P  PV   V  P  S +P  P   +S  P  PPP   +PPP+PP
Sbjct: 323 AKDTPE-PVKEEVTVPATSQVPESP---SSEEPPLPPPNEEVPPPLPP 366



 Score = 31.6 bits (70), Expect = 5.0
 Identities = 78/370 (21%), Positives = 118/370 (31%), Gaps = 78/370 (21%)

Query: 655 VPPAFPVSMPV--PPPGFS----PIPPPPFLRASFNPSQ-------------------PP 689
           VPP  PV++P   P PG+S    P  P      SF                        P
Sbjct: 19  VPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQCVLQP 78

Query: 690 PGFMPPPVPPPVV------------PPPTIPPVVPTSLVQPSLSMTPETVKDVGFGSLVI 737
               PPP+PPP V            PPP  PP  P    Q       + +     G   +
Sbjct: 79  HHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGL 138

Query: 738 PGGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDHQISSGENTRSVIPNDISSNAA 797
               + S   +  +P G+ +  P++   P  + P              S  P   SS   
Sbjct: 139 VPMELESPPESPPVPPGS-YMPPSQSYMPPPQPP-------------PSYYP-PTSSQPY 183

Query: 798 ILGGQP-PNVTSNSGILGVQRPNVSSNSEILGVRPSNVSSSSGIIAAQPPNILNNSGILG 856
           +   QP P+ +  S       P+ SS+           SSSS    +   + L +S    
Sbjct: 184 LPPAQPSPSQSPPSQSYLAPTPSYSSS-----------SSSSQSYLSHSQSYLPSSQASP 232

Query: 857 IQPPSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGLLGTQPPAGPQNLPPLSIPNQ 916
            +P    + S LL   PP+ P  +     Q P           Q  A P+  P    P +
Sbjct: 233 SRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQE 292

Query: 917 RMP---TMPMLDIRPGLIPQAPG-PRFPLI----------QPGIPPQRGIPPPSVLDSAL 962
           +        +L ++       PG  + P++          +  +P    +P     +   
Sbjct: 293 QQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPP 352

Query: 963 HPPPRGPFPP 972
            PPP    PP
Sbjct: 353 LPPPNEEVPP 362



 Score = 31.2 bits (69), Expect = 6.6
 Identities = 29/110 (26%), Positives = 40/110 (36%), Gaps = 14/110 (12%)

Query: 873 PPNIPNNSGLVGVQPPNVPNTPGLLGTQPPAGPQNLPPLSIPNQRMPTMPMLDIRPGLIP 932
           PP +P       V  P     PG   +  PA P +   +S   Q +  +  L        
Sbjct: 16  PPPVPPPPP---VALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQM 72

Query: 933 QAPGPRFPLIQPGIPPQRGIPPPSVLDSALH-----PPPRGPFPPGDIFS 977
           Q       ++QP   P   +PPP V+    +     PPP  P PPG   S
Sbjct: 73  QC------VLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALS 116


>gi|4508017 zinc finger protein 207 isoform a [Homo sapiens]
          Length = 478

 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 92/388 (23%), Positives = 134/388 (34%), Gaps = 71/388 (18%)

Query: 614 TTQSPTPVEKETVVTTQAEVFPPPVAMLQIPVAPAVPTVSLVPPAFPVSMP-VPP--PGF 670
           T+  P PV+ +       + + PP+A   +P  P  P +   PP  P  MP VPP  PG 
Sbjct: 125 TSFQPQPVQPQ-------QGYIPPMAQPGLPPVPGAPGM---PPGIPPLMPGVPPLMPGM 174

Query: 671 SPIPP--PPFLRASFNPSQPPPGF----------MPPPVPPPVVPPPTI----------- 707
            P+ P  PP +        P PG           MPPPVP P +PP T            
Sbjct: 175 PPVMPGMPPGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILN 234

Query: 708 -PPVVPTSLVQPSLSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEP 766
            PP    ++  P   +T       G     +   S AS+ + S   +       T QA+ 
Sbjct: 235 RPPAPTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQA 294

Query: 767 EEKVPHLIDHQISSGENTRSVIPNDISSNAAILGGQPPNVTSNSGILGVQRPNVSSNSEI 826
             + P   D +  +     +  P   +  A          T+NS      +P  S  S  
Sbjct: 295 AVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNST---AAKPAASITS-- 349

Query: 827 LGVRPSNVSSSSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQ 886
              +P+ ++++S       P+   +      Q P    +    G  P   P    + G+ 
Sbjct: 350 ---KPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMM 406

Query: 887 PPN--VPNTPGLLGTQPPAGPQNLPPLSIPNQRMPTMPMLDIRPGLIPQAPGPRFPLIQP 944
           PP   +P   G+    PP G        +P      MP         P   GP      P
Sbjct: 407 PPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMP---------PYGQGP------P 451

Query: 945 GIPPQRGIPPPSVLDSALHPPPRGPFPP 972
            +PP +G PP          PP G  PP
Sbjct: 452 MVPPYQGGPP---------RPPMGMRPP 470



 Score = 37.7 bits (86), Expect = 0.070
 Identities = 42/154 (27%), Positives = 54/154 (35%), Gaps = 21/154 (13%)

Query: 905  PQNLPPLS--IPNQRMPTMPMLDIRPGLIPQAPG--PRFPLIQPGIPPQRGIPPPSVLDS 960
            PQ + P    IP    P +P +   PG+ P  P   P  P + PG+PP     PP ++  
Sbjct: 129  PQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGMM-- 186

Query: 961  ALHPPPRGPFPPGDIFSQPERPFLAPGRQSVDNVTNPEKRIPLGNDNIQQEGDRDYRFPP 1020
                P  G  PPG     P  P L PG         P   IP                PP
Sbjct: 187  ----PMGGMMPPG-----PGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPP 237

Query: 1021 IETRESISRPPPVDVRDVVGRPIDPREGPGRPPL 1054
              T    +  PPV       +P+ P  G    P+
Sbjct: 238  APTATVPAPQPPVT------KPLFPSAGQMGTPV 265


>gi|9558733 transformer-2 alpha [Homo sapiens]
          Length = 282

 Score = 66.6 bits (161), Expect = 1e-10
 Identities = 51/166 (30%), Positives = 79/166 (47%), Gaps = 10/166 (6%)

Query: 398 SRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRKRSRSRSRERKRKSSRSYSSE-RRARERE 456
           SR   HS S SRS  K RSRSR  S +R  R RS S S  R+R  SRSY+ E RR R R 
Sbjct: 40  SRVSKHSESHSRSRSKSRSRSRRHSHRRYTRSRSHSHS-HRRRSRSRSYTPEYRRRRSRS 98

Query: 457 KERQKKGLPPIRSKTLSVCSTTLWVGQVDKKATQQDLTNLFEEFGQIESINMI------P 510
                       S+     +T L V  +    T++DL  +F  +G +  +N++       
Sbjct: 99  HSPMSNRRRHTGSRANPDPNTCLGVFGLSLYTTERDLREVFSRYGPLSGVNVVYDQRTGR 158

Query: 511 PRGCAYVCMVHRQDAFRALQKLSSGSYKIGSKVIKIAWALNKGVKT 556
            RG A+V      D+  A+++  +   ++  + I++ +++ K   T
Sbjct: 159 SRGFAFVYFERIDDSKEAMER--ANGMELDGRRIRVDYSITKRAHT 202


>gi|4759098 splicing factor, arginine/serine-rich 10 [Homo sapiens]
          Length = 288

 Score = 66.6 bits (161), Expect = 1e-10
 Identities = 52/173 (30%), Positives = 87/173 (50%), Gaps = 12/173 (6%)

Query: 389 QEAKKVAVRSRSRTHSRSRSRSPRKRRSRSRSGSRK--RKHRKRSRSRSRERKRKSSRSY 446
           + A+    RSRS+  SR RSRS  + RS SRS SR+  R+H  RSRSRSR  +R  SRSY
Sbjct: 28  KSARHTPARSRSKEDSR-RSRSKSRSRSESRSRSRRSSRRHYTRSRSRSRSHRRSRSRSY 86

Query: 447 SSE-RRAREREKERQKKGLPPIRSKTLSVCSTTLWVGQVDKKATQQDLTNLFEEFGQIES 505
           S + RR               + ++     +  L V  +    T++DL  +F ++G I  
Sbjct: 87  SRDYRRRHSHSHSPMSTRRRHVGNRANPDPNCCLGVFGLSLYTTERDLREVFSKYGPIAD 146

Query: 506 INMI------PPRGCAYVCMVHRQDAFRALQKLSSGSYKIGSKVIKIAWALNK 552
           ++++        RG A+V   +  DA  A ++  +   ++  + I++ +++ K
Sbjct: 147 VSIVYDQQSRRSRGFAFVYFENVDDAKEAKER--ANGMELDGRRIRVDFSITK 197


>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
          Length = 1682

 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 112/431 (25%), Positives = 151/431 (35%), Gaps = 71/431 (16%)

Query: 660  PVSMPVPPPGFSP------IPPPPFLRASFNPSQP--PPGFM--PPPVPPPVVPPPTIPP 709
            PV  PVPP   S       + P    R   N  Q   PPG    PPP+PPP  PPP  PP
Sbjct: 204  PVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPPLPPPPPPPPPPPP 263

Query: 710  VVPTSLVQPSLSMTPETVKDVGFGSLVIP--GGSVASNLATS--ALPAGNVFNAPTKQAE 765
             +P     P   +T   +     G    P   GS          +LP    + AP   A 
Sbjct: 264  PLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLPHPYPYPAPAYTAH 323

Query: 766  PEEKVPHLIDHQISSGENTRSVIPNDISSNAAILGGQPPNVTSNSGILGVQRPNVSSNSE 825
            P     H +      G   R   P    S+  +   +PP   S+     VQR  + S+  
Sbjct: 324  PP---GHRLVPAAPPGPGPR---PPGAESHGCLPATRPPG--SDLRESRVQRSRMDSS-- 373

Query: 826  ILGVRPSNVSSSSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGLVGV 885
               V P+  ++      ++PP +    G       S S+++GL GV P     N G+ G 
Sbjct: 374  ---VSPAATTACVPYAPSRPPGL---PGTTTSSSSSSSSNTGLRGVEP-----NPGIPGA 422

Query: 886  QPPNVP----NTPGLLGTQPPAGPQNLPPLSIPNQRMPTMPMLDIRPGLIPQAPGPRFPL 941
                 P    +  G LG  P A     P L  P       P L + PG     P P   L
Sbjct: 423  DHYQTPALEVSHHGRLG--PSAHSSRKPFLGAP----AATPHLSLPPGPSSPPPPPCPRL 476

Query: 942  IQPGIPPQRGIPPPSV------------LDSALHPPPR---GPFPPGDIFSQPERPFLAP 986
            ++P  PP   +  P+             L      PPR    P P  + F  P     + 
Sbjct: 477  LRPP-PPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSV 535

Query: 987  GRQSVDNVTNPEKRIPLGNDNIQQEGDRDYRFPPIETRESISRPPPVDVR---DVVGRPI 1043
            G Q  D+ T P    P  + +    G              +S PPP  +    D + RP 
Sbjct: 536  GTQ--DSHTPPTPPTPTTSSSNSNSGSHS-----SSPAGPVSFPPPPYLARSIDPLPRPP 588

Query: 1044 DPREGPGRPPL 1054
             P + P  PPL
Sbjct: 589  SPAQNPQDPPL 599



 Score = 41.2 bits (95), Expect = 0.006
 Identities = 35/98 (35%), Positives = 41/98 (41%), Gaps = 18/98 (18%)

Query: 602 VKSSEPVKETVQTTQSPTPVEKETVVTTQAEVFPPPVAMLQIPVAPAVPTVSLVPPAFPV 661
           V    P+KE   + QSP P +  T  TT A    P VA+          T +    A   
Sbjct: 719 VAPQPPLKEPFASLQSPFPTD--TAPTTTA----PAVAVT------TTTTTTTTTTATQE 766

Query: 662 SMPVPPPGFSPIPPPPFLRASFNPSQPPPGFMPPPVPP 699
               PPP    +PPPP L     PSQP P   PPP PP
Sbjct: 767 EEKKPPPA---LPPPPPLAKFPPPSQPQP---PPPPPP 798



 Score = 40.8 bits (94), Expect = 0.008
 Identities = 27/75 (36%), Positives = 33/75 (44%), Gaps = 2/75 (2%)

Query: 644 PVAPAVPTVSLVPPAFPVSMPVPPPGFSPIPPPPFLRASFNPSQPPPGFMPPPVPPPVVP 703
           P  P  PT S    +   S    P G    PPPP+L  S +P   PP     P  PP+VP
Sbjct: 543 PPTPPTPTTSS-SNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVP 601

Query: 704 -PPTIPPVVPTSLVQ 717
               +PP  P+S  Q
Sbjct: 602 LTLALPPAPPSSCHQ 616



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 95/385 (24%), Positives = 131/385 (34%), Gaps = 113/385 (29%)

Query: 677  PFLRASFNPSQPPPGFMPPPVPPPVVPPPTIPPVVPTSLVQPSLSMTPETVKDVGFGSLV 736
            P L     PS PPP    PP P  + PPP  PP         +     E ++++ FG+  
Sbjct: 457  PHLSLPPGPSSPPP----PPCPRLLRPPP--PPAWLKGPACRAAREDGEILEELFFGTEG 510

Query: 737  IPGGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDHQISSGENTRSVIPNDISSNA 796
             P        A   LP    F  P                + S G       P       
Sbjct: 511  PP------RPAPPPLPHREGFLGPPAS-------------RFSVGTQDSHTPPT------ 545

Query: 797  AILGGQPPNVTSNSGILGVQRPNVSSNSEILGVRPSNVSSSSGIIAAQPPNILNNSGILG 856
                  PP  T++S          +SNS       S+ SS +G ++  PP  L  S    
Sbjct: 546  ------PPTPTTSSS---------NSNSG------SHSSSPAGPVSFPPPPYLARSIDPL 584

Query: 857  IQPPSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGLLGTQPPAGPQNLPPLSIPNQ 916
             +PPS           P   P +       PP VP T  L    PPA P +    +  + 
Sbjct: 585  PRPPS-----------PAQNPQD-------PPLVPLTLAL----PPAPPSSCHQNTSGSF 622

Query: 917  RMPTMPMLDIRPGLIPQAPGPRFPLIQPGIPPQRGIPPPSVLDSALHP--------PPRG 968
            R P  P         P+   P+ P + PG       PPP  L  A  P        P RG
Sbjct: 623  RRPESPR--------PRVSFPKTPEVGPG-------PPPGPLSKAPQPVPPGVGELPARG 667

Query: 969  P----FPPGDIFSQPERPFLAPGRQSVDNVTNPEKRIPLGNDNIQQEGDRDYR------F 1018
            P    FPP  +  Q E P  A  +   D + N  K +   +++I++E ++          
Sbjct: 668  PRLFDFPPTPLEDQFEEP--AEFKILPDGLANIMKML---DESIRKEEEQQQHEAGVAPQ 722

Query: 1019 PPI-ETRESISRPPPVDVRDVVGRP 1042
            PP+ E   S+  P P D       P
Sbjct: 723  PPLKEPFASLQSPFPTDTAPTTTAP 747



 Score = 38.1 bits (87), Expect = 0.054
 Identities = 51/225 (22%), Positives = 76/225 (33%), Gaps = 75/225 (33%)

Query: 574 EKVKVDDLEGFAEGGMIDQETVNTEWETVKSSEPVKETVQTTQSP-------TPVEKETV 626
           E ++ ++ +   E G+  Q  +   + +++S  P  +T  TT +P       T     T 
Sbjct: 704 ESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPT-DTAPTTTAPAVAVTTTTTTTTTTT 762

Query: 627 VTTQAEVFPPPVAMLQIPVA----PAVPTVSLVPPAFPVSM------------------- 663
            T + E  PPP      P+A    P+ P     PP  P S+                   
Sbjct: 763 ATQEEEKKPPPALPPPPPLAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTG 822

Query: 664 ----------------PVPPPGFSPIPPP---PFLRASFNPS------------------ 686
                           P PP G + +PP    P  + S  PS                  
Sbjct: 823 AAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARER 882

Query: 687 ----QPPPGFMPPPVPPPVVPPPTIPPVVPTSLVQPSLSMTPETV 727
               +P PG M P  PP   PP ++PP    S V   +S   ET+
Sbjct: 883 RAGEEPVPGPMTPTQPP---PPLSLPPARSESEVLEEISRACETL 924



 Score = 37.7 bits (86), Expect = 0.070
 Identities = 33/92 (35%), Positives = 34/92 (36%), Gaps = 3/92 (3%)

Query: 635 PPPVAMLQIPVAPAVPTVSLVPPAFPVSMPVPPPGFSPIPPPPFLRASFNPSQPPPGFMP 694
           P P    Q P  P VP    +PPA P S      G    P  P  R SF P  P  G  P
Sbjct: 588 PSPAQNPQDP--PLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSF-PKTPEVGPGP 644

Query: 695 PPVPPPVVPPPTIPPVVPTSLVQPSLSMTPET 726
           PP P    P P  P V       P L   P T
Sbjct: 645 PPGPLSKAPQPVPPGVGELPARGPRLFDFPPT 676


>gi|33620745 pre-mRNA cleavage complex II protein Pcf11 [Homo
           sapiens]
          Length = 1555

 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 106/496 (21%), Positives = 206/496 (41%), Gaps = 68/496 (13%)

Query: 22  SKAKMTQITKAAIKAIKFYKHVVQSVEKFIQKCKPEYKVPGLYVIDSIVRQSRHQFGQEK 81
           SK  +  +T  A + + F K +V  +E    K     K+P +Y++DSIV+      G+E 
Sbjct: 33  SKPHINMLTILAEENLPFAKEIVSLIEAQTAKAPSSEKLPVMYLMDSIVKN----VGRE- 87

Query: 82  DVFAPRFSNNIISTFQNLYRCPGDDKSK-IVRVLNLWQK----NNVFKSEIIQPLLDMAA 136
             +   F+ N+++TF  ++    ++  K + ++ + W +      ++  ++    LD A 
Sbjct: 88  --YLTAFTKNLVATFICVFEKVDENTRKSLFKLRSTWDEIFPLKKLYALDVRVNSLDPAW 145

Query: 137 GI---PPPVVTPVLASTTTAMSNTPGTPVTPVTPANVVQGLPDPWVSQIT-NTDTLAAVA 192
            I   PP V T  +      ++ +P  P TP T  +       P V  I  N      + 
Sbjct: 146 PIKPLPPNVNTSSIHVNPKFLNKSPEEPSTPGTVVSSPSISTPPIVPDIQKNLTQEQLIR 205

Query: 193 QILQSPQGQ--QLQQLIQTLQIQQQKPQPSI---LQALDAGL---VVQLQALTAQLTAAA 244
           Q L + Q Q  +LQQ    L+++Q K Q ++   +Q   + L       +   +Q+   A
Sbjct: 206 QQLLAKQKQLLELQQKKLELELEQAKAQLAVSLSVQQETSNLGPGSAPSKLHVSQIPPMA 265

Query: 245 AAANTLTPLE---------------QGVSFNKKL--MDRFDFGEDSEHSEE--------- 278
             A    P++               +G + + +L  + +   G+D  H +E         
Sbjct: 266 VKAPHQVPVQSEKSRPGPSLQIQDLKGTNRDPRLNRISQHSHGKDQSHRKEFLMNTLNQS 325

Query: 279 ---PKKEIPASQLSHVSESVNNSIFHQIAEQLQQQNLEHLRQQLLEQQQPQKATP-QDSQ 334
                K IP+ +L+   +  + S      E++ ++ L+ L  +   + + +  +P ++  
Sbjct: 326 DTKTSKTIPSEKLNSSKQEKSKS-----GEKITKKELDQLDSK--SKSKSKSPSPLKNKL 378

Query: 335 EGTFGSEHSASPSQGSSQQHFLEPEV--NLDDSIDIQQQDMDIDEGQDGVEEEVFEQEAK 392
             T   ++  S S   S  +  +P +  +L D  D   +D D+ E +   E++  ++  K
Sbjct: 379 SHTKDLKNQESESMRLSDMNKRDPRLKKHLQDKTD--GKDDDVKEKRKTAEKKDKDEHMK 436

Query: 393 KVAVR---SRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRKRSRSRSRERKRKSSRSYSSE 449
               R   SR++  +    +         + G++  +   R RSRSR  K +S   +S +
Sbjct: 437 SSEHRLAGSRNKIINGIVQKQDTITEESEKQGTKPGRSSTRKRSRSRSPKSRSPIIHSPK 496

Query: 450 RRAREREKERQKKGLP 465
           RR R   K RQ+   P
Sbjct: 497 RRDRRSPKRRQRSMSP 512


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 65.1 bits (157), Expect = 4e-10
 Identities = 100/392 (25%), Positives = 133/392 (33%), Gaps = 78/392 (19%)

Query: 607 PVKETVQTTQSPTPVEKETVVTTQAEVFPPPVAMLQIPVAPAVPTVSLVPPAFPVSMPVP 666
           P       +Q+ T +   T+  T + +  PP++ L  P   A P ++L P   P S P  
Sbjct: 355 PSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPAS 414

Query: 667 PPGFSPIPPPP----------FLRASFNPSQPPPGFMP--PPVPPPVVPPPTIPPVVPTS 714
           PP  SP+  P            L+A F+P   PP   P  PP  PPV P  T P   P S
Sbjct: 415 PP-LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPS 473

Query: 715 LVQPSLSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLI 774
           L  P L + P             P       LA   L        P  QA P    P L 
Sbjct: 474 LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAK----PPPQAPPALATPPL- 528

Query: 775 DHQISSGENTRSVIPNDISSNAAILGGQPPNVTSNSGILG------VQRPNVSSNSEILG 828
                            + S  A   GQ P   S S  +        Q P V + + +L 
Sbjct: 529 ---------------QALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLA-APLLQ 572

Query: 829 VRPSNVSSSSGIIAAQPPNILNNSGILGIQ-----------PPSVSNSSGLLGVLPPNIP 877
           V PS  +S +     +PP    ++ + G +           PPS S SS L G   P++ 
Sbjct: 573 VPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSG---PDLA 629

Query: 878 NNSGLVGVQPPNVPNTPGLLGTQPPAGPQNLPPLSIPNQRMPTMPMLDIRPGLIPQAPGP 937
            +S      P  +        + P  G    PP        P   +    P    + P P
Sbjct: 630 GHSSSATSTPEELRG----YDSGPEGGAAASPP--------PDAELAACHPAAWSRGPAP 677

Query: 938 RFPLIQPGIPPQRGIPPPSVLDSALHPPPRGP 969
             PL   G P   G P P        PP  GP
Sbjct: 678 --PLAFRGAP---GAPLP-------WPPATGP 697



 Score = 58.2 bits (139), Expect = 5e-08
 Identities = 119/489 (24%), Positives = 167/489 (34%), Gaps = 103/489 (21%)

Query: 605  SEPVKETVQTTQSP--TPVEKETV-----VTTQAEVFPPPVAMLQI---PVAPAVPTVSL 654
            S+P  + +Q  + P  TP  K+       +++     P P A LQ    P  PA P  S 
Sbjct: 270  SQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSS 329

Query: 655  VPPAFPVSMPVPPPGFSPIPPPPFLRASFNPSQPPP---------------GFMP-PPVP 698
            +       +P+ PP   P  PP        P+ PP                 F+P PP+ 
Sbjct: 330  LTCQLATPLPLAPPS--PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLS 387

Query: 699  PPVVPPPTIPPVVPTSLVQPSLSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFN 758
            P   PPP  PP    +L  P L   P          L  P     + LA   L A   F+
Sbjct: 388  PLATPPPQAPP----ALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQA--PFS 441

Query: 759  APTKQAEPEEKVPHLIDHQISSGENTRSVIPNDISSNAAILGGQPPNVTSNSGILGVQRP 818
             P     P  + P        S   +  V P+    + A     PP++ +          
Sbjct: 442  PP---PSPPVQAPF-------SPPASPPVSPSATPPSQA-----PPSLAAPP-------- 478

Query: 819  NVSSNSEILGVRPSNVSSSSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPN 878
                    L V PS  +S     +A PP            PP ++     L   PP  P 
Sbjct: 479  --------LQVPPSPPASPPMSPSATPP---------PQAPPPLAAPPLQLAKPPPQAPP 521

Query: 879  NSGLVGVQPPNVPNTPGLLGTQPPAGPQ-NLP--PLSIPNQRMPTM---PMLDIRPGLIP 932
                  +Q   +P+ P     Q P  P  +LP  PL+ P  + P +   P+L + P   P
Sbjct: 522  ALATPPLQA--LPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPS-PP 578

Query: 933  QAPGPRFPLIQPGIPPQRGIPPPSV-LDSALHPPPRGPFPPGDIFSQPERPFLAPGRQSV 991
             +P  + P   P   P   +  P + L  A  PPP     P    S P+      G  S 
Sbjct: 579  ASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPD----LAGHSSS 634

Query: 992  DNVTNPEKRIPLGNDNIQQEGDRDYRFPPIETRESISRP--------PPVDVRDVVGRPI 1043
               T  E R   G D+  + G      PP +   +   P        PP+  R   G P+
Sbjct: 635  ATSTPEELR---GYDSGPEGGAA--ASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPL 689

Query: 1044 --DPREGPG 1050
               P  GPG
Sbjct: 690  PWPPATGPG 698



 Score = 51.6 bits (122), Expect = 5e-06
 Identities = 100/425 (23%), Positives = 137/425 (32%), Gaps = 89/425 (20%)

Query: 653  SLVPPAFPVSMPVPPPGFSPIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPP-----PTI 707
            SL   A P+S P      +   P    RA  +PSQP P  +    PP V PP     P +
Sbjct: 241  SLSSSATPLSSPARSGPSARGTP----RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL 296

Query: 708  PPVVPTSLVQPS-----LSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTK 762
             P+  + L  PS      S  P T+      S      S+   LAT           P  
Sbjct: 297  GPLSSSPLATPSPSAALQSQAPPTLPATPHSS------SLTCQLAT-----------PLP 339

Query: 763  QAEPEEKVPHLIDHQISSGENTRSVIPNDISSNAAILGGQPPNVTSNSGILGVQRPNVSS 822
             A P    P  +             +P+            PP    +     +  P + +
Sbjct: 340  LAPPSPSAPPSL-----------QTLPS------------PPATPPSQATTSLGSPTLQA 376

Query: 823  NSEILGVRPSNVSSSSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGL 882
                L   PS   S       Q P  L    +     P  S     L    P  PN   +
Sbjct: 377  THSFL---PSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAV 433

Query: 883  VGVQPP--NVPNTPGLLGTQPPAGPQNLPPLSIPNQRMPTMPMLDIRPGLIPQAPGPRFP 940
              +Q P    P+ P      PPA P   P  + P+Q  P+   L   P  +P +P P  P
Sbjct: 434  HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPS---LAAPPLQVPPSP-PASP 489

Query: 941  LIQPGIPPQRGIPPPSVLD--SALHPPPRGP----FPPGDIFSQPERPFLAPGRQSVDNV 994
             + P   P    PPP          PPP+ P     PP  + + P  P   PG+      
Sbjct: 490  PMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPP--LQALPSPPASFPGQAPF--- 544

Query: 995  TNPEKRIPLGNDNIQQEGDRDYRFPPIETRESISRPPPVDVRDVVGRPIDPR-EGPGRPP 1053
             +P   +P+             + PP+     +  PP          P  P  + P RPP
Sbjct: 545  -SPSASLPM-----SPLATPPPQAPPVLAAPLLQVPP--------SPPASPTLQAPRRPP 590

Query: 1054 LDGRD 1058
              G D
Sbjct: 591  TPGPD 595



 Score = 38.1 bits (87), Expect = 0.054
 Identities = 91/425 (21%), Positives = 138/425 (32%), Gaps = 71/425 (16%)

Query: 681  ASFNPSQPPPGFMPP-PVPPPVVPPPTIPPVVPTSLVQPSLSMTPETVKDVGFGSLVIP- 738
            A+  P+   PG + P P   P  PPP  P  +       ++   P   +  G G   IP 
Sbjct: 13   AARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPE 72

Query: 739  ----------GGSVASNLATSALPAGNVFNA-PTKQAEP-------------------EE 768
                       G+ + N A+    +G    A P K   P                   ++
Sbjct: 73   SAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQK 132

Query: 769  KVPHLIDHQISSGENTRSVIPNDISSNAAILGGQPPNVTSNSGI----------LGVQRP 818
             +    +  ++ G+ T +   + +S+ A      P   T +  +          +G+ RP
Sbjct: 133  GLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRP 192

Query: 819  NVSSNSEILGVRP-SNVSSSSGIIAAQPPNILNN--SGILGIQPPSVSNSSGLLGVLPPN 875
              S+        P  +VSS+S     +P        S   G+Q P+  + S      P +
Sbjct: 193  APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS--SATPLS 250

Query: 876  IPNNSGLVGVQPPNVPNTPGLLGTQP-PAGPQNLPPLSIPNQRMPTMPMLDIRPGLIPQA 934
             P  SG      P  P  P    +QP P G Q L P  +   R    P L          
Sbjct: 251  SPARSGPSARGTPRAPAHP----SQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLAT 306

Query: 935  PGPRFPLIQPGIPPQRGIPPPSVLDSALHPP----PRGPFPPGDIFSQPERPFLAPGRQS 990
            P P   L     P     P  S L   L  P    P  P  P  + + P  P   P + +
Sbjct: 307  PSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAT 366

Query: 991  VDNVTNPEKRIPLGNDNIQQEGDRDYRFPPIETRESISRPPPVDVRDVVGRPID-PREGP 1049
                        LG+  +Q      + F P      ++ PPP     +   P+  P   P
Sbjct: 367  TS----------LGSPTLQ----ATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPP 412

Query: 1050 GRPPL 1054
              PPL
Sbjct: 413  ASPPL 417


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 65.1 bits (157), Expect = 4e-10
 Identities = 100/392 (25%), Positives = 133/392 (33%), Gaps = 78/392 (19%)

Query: 607 PVKETVQTTQSPTPVEKETVVTTQAEVFPPPVAMLQIPVAPAVPTVSLVPPAFPVSMPVP 666
           P       +Q+ T +   T+  T + +  PP++ L  P   A P ++L P   P S P  
Sbjct: 316 PSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPAS 375

Query: 667 PPGFSPIPPPP----------FLRASFNPSQPPPGFMP--PPVPPPVVPPPTIPPVVPTS 714
           PP  SP+  P            L+A F+P   PP   P  PP  PPV P  T P   P S
Sbjct: 376 PP-LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPS 434

Query: 715 LVQPSLSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLI 774
           L  P L + P             P       LA   L        P  QA P    P L 
Sbjct: 435 LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAK----PPPQAPPALATPPL- 489

Query: 775 DHQISSGENTRSVIPNDISSNAAILGGQPPNVTSNSGILG------VQRPNVSSNSEILG 828
                            + S  A   GQ P   S S  +        Q P V + + +L 
Sbjct: 490 ---------------QALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLA-APLLQ 533

Query: 829 VRPSNVSSSSGIIAAQPPNILNNSGILGIQ-----------PPSVSNSSGLLGVLPPNIP 877
           V PS  +S +     +PP    ++ + G +           PPS S SS L G   P++ 
Sbjct: 534 VPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSG---PDLA 590

Query: 878 NNSGLVGVQPPNVPNTPGLLGTQPPAGPQNLPPLSIPNQRMPTMPMLDIRPGLIPQAPGP 937
            +S      P  +        + P  G    PP        P   +    P    + P P
Sbjct: 591 GHSSSATSTPEELRG----YDSGPEGGAAASPP--------PDAELAACHPAAWSRGPAP 638

Query: 938 RFPLIQPGIPPQRGIPPPSVLDSALHPPPRGP 969
             PL   G P   G P P        PP  GP
Sbjct: 639 --PLAFRGAP---GAPLP-------WPPATGP 658



 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 113/449 (25%), Positives = 153/449 (34%), Gaps = 95/449 (21%)

Query: 635  PPPVAMLQIPVAPAVPTVSLVPPAFPVSMPVPPPGFSPIPPPPFLRASFNPSQPPP---- 690
            PP V   +   APA+  +S  P A P   P  PP  SP  PP        P+ PP     
Sbjct: 273  PPQVTPPRKDAAPALGPLSSSPLATP--SPSAPP--SPSAPPSLQTLPSPPATPPSQATT 328

Query: 691  -----------GFMP-PPVPPPVVPPPTIPPVVPTSLVQPSLSMTPETVKDVGFGSLVIP 738
                        F+P PP+ P   PPP  PP    +L  P L   P          L  P
Sbjct: 329  SLGSPTLQATHSFLPSPPLSPLATPPPQAPP----ALALPPLQAPPSPPASPPLSPLATP 384

Query: 739  GGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDHQISSGENTRSVIPNDISSNAAI 798
                 + LA   L A   F+ P     P  + P        S   +  V P+    + A 
Sbjct: 385  SPQAPNALAVHLLQA--PFSPP---PSPPVQAPF-------SPPASPPVSPSATPPSQA- 431

Query: 799  LGGQPPNVTSNSGILGVQRPNVSSNSEILGVRPSNVSSSSGIIAAQPPNILNNSGILGIQ 858
                PP++ +                  L V PS  +S     +A PP            
Sbjct: 432  ----PPSLAAPP----------------LQVPPSPPASPPMSPSATPP---------PQA 462

Query: 859  PPSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGLLGTQPPAGPQ-NLP--PLSIPN 915
            PP ++     L   PP  P       +Q   +P+ P     Q P  P  +LP  PL+ P 
Sbjct: 463  PPPLAAPPLQLAKPPPQAPPALATPPLQA--LPSPPASFPGQAPFSPSASLPMSPLATPP 520

Query: 916  QRMPTM---PMLDIRPGLIPQAPGPRFPLIQPGIPPQRGIPPPSV-LDSALHPPPRGPFP 971
             + P +   P+L + P   P +P  + P   P   P   +  P + L  A  PPP     
Sbjct: 521  PQAPPVLAAPLLQVPPS-PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRS 579

Query: 972  PGDIFSQPERPFLAPGRQSVDNVTNPEKRIPLGNDNIQQEGDRDYRFPPIETRESISRP- 1030
            P    S P+      G  S    T  E R   G D+  + G      PP +   +   P 
Sbjct: 580  PSSTLSGPD----LAGHSSSATSTPEELR---GYDSGPEGGAA--ASPPPDAELAACHPA 630

Query: 1031 -------PPVDVRDVVGRPI--DPREGPG 1050
                   PP+  R   G P+   P  GPG
Sbjct: 631  AWSRGPAPPLAFRGAPGAPLPWPPATGPG 659



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 103/426 (24%), Positives = 136/426 (31%), Gaps = 100/426 (23%)

Query: 653  SLVPPAFPVSMPVPPPGFSPIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPP-----PTI 707
            SL   A P+S P      +   P    RA  +PSQP P  +    PP V PP     P +
Sbjct: 232  SLSSSATPLSSPARSGPSARGTP----RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL 287

Query: 708  PPVVPTSLVQPSLSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEPE 767
             P+  + L  PS S  P         +L  P  +  S   TS         +PT QA   
Sbjct: 288  GPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTS-------LGSPTLQA--- 337

Query: 768  EKVPHLIDHQISSGENTRSVIPNDISSNAAILGGQPPNVTSNSGILGVQRPNVSSNSEIL 827
                            T S +P   S   + L   PP       +  +Q P     S  L
Sbjct: 338  ----------------THSFLP---SPPLSPLATPPPQAPPALALPPLQAPPSPPASPPL 378

Query: 828  GVRPSNVSSSSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQP 887
                         +A   P   N   +  +Q P            PP+ P  +      P
Sbjct: 379  SP-----------LATPSPQAPNALAVHLLQAPFSP---------PPSPPVQAPFS--PP 416

Query: 888  PNVPNTPGLLGTQPPAGPQNL--PPLSIPNQRMPTMPMLDIRPGLIPQAPGPRFPLIQPG 945
             + P +P    T P   P +L  PPL +P    P  P +       PQAP P        
Sbjct: 417  ASPPVSPS--ATPPSQAPPSLAAPPLQVPPSP-PASPPMSPSATPPPQAPPPL------A 467

Query: 946  IPPQRGIPPPSVLDSALHPPP-------------RGPFPPGDIFSQPERPFLAPGRQSVD 992
             PP +   PP     AL  PP             + PF P    S P  P   P  Q+  
Sbjct: 468  APPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPS--ASLPMSPLATPPPQAPP 525

Query: 993  NVTNPEKRIPLGNDNIQQEGDRDYRFPPIETRESISRPP-PVDVRDVVGRPIDPREGPGR 1051
             +  P  ++P                P   T ++  RPP P     V G  +     PG 
Sbjct: 526  VLAAPLLQVPPSP-------------PASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP 572

Query: 1052 PPLDGR 1057
            PP   R
Sbjct: 573  PPPPSR 578



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 59/222 (26%), Positives = 81/222 (36%), Gaps = 27/222 (12%)

Query: 605 SEPVKETVQTTQSPTPVEKETVVTTQAEVFPPPVAMLQIPVAPAVPTVSLVPPAFPVSMP 664
           S PV+       SP PV       +QA   PP +A   + V P+ P    + P+      
Sbjct: 406 SPPVQAPFSPPASP-PVSPSATPPSQA---PPSLAAPPLQVPPSPPASPPMSPSATPPPQ 461

Query: 665 VPPPGFSP-----IPPP--------PFLRASFNPSQPPPGFMP------PPVPPPVVPPP 705
            PPP  +P      PPP        P L+A  +P    PG  P       P+ P   PPP
Sbjct: 462 APPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPP 521

Query: 706 TIPPVVPTSLVQ--PSLSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQ 763
             PPV+   L+Q  PS   +P T++         P  SV+    T AL  G     P++ 
Sbjct: 522 QAPPVLAAPLLQVPPSPPASP-TLQAPRRPPTPGPDTSVSGPRLTLALAPGPP-PPPSRS 579

Query: 764 AEPEEKVPHLIDHQISSGENTRSVIPNDISSNAAILGGQPPN 805
                  P L  H  S+      +   D           PP+
Sbjct: 580 PSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPD 621



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 82/378 (21%), Positives = 122/378 (32%), Gaps = 70/378 (18%)

Query: 681 ASFNPSQPPPGFMPPPVP-PPVVPPPTIPPVVPTSLVQPSLSMTPETVKDVGFGSLVIPG 739
           A+  P+   PG + P  P  P  PPP  P  +       ++   P   +  G G   IP 
Sbjct: 13  AARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPE 72

Query: 740 GSV-----------ASNLATSALPAGNVFNAP---------TKQAEP--EEKVPHLIDHQ 777
            +            AS     A PA N    P         T +  P  ++ +    +  
Sbjct: 73  SAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEET 132

Query: 778 ISSGENTRSVIPNDISSNAA------ILGGQPPNVTSNSGILGVQ--------------- 816
           ++ G+ T +   + +S+ A         G   P +   S   G +               
Sbjct: 133 VARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPP 192

Query: 817 ----RPNVSSNSEILGVRPSNVSS---SSGIIAAQPPNILNNSGILGIQPPSVSNSSGL- 868
               R +VSS SE     PS  +    S+G    +P +   +S    +  P+ S  S   
Sbjct: 193 TEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARG 252

Query: 869 --LGVLPPNIPNNSGLVGVQPPNVPNTPGLLGTQPPAGPQNLPPLSIPNQRMPTMPMLDI 926
                  P+ P   GL  ++PP V  TP      P  GP +  PL+ P+   P  P    
Sbjct: 253 TPRAPAHPSQPKPKGLQALRPPQV--TPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310

Query: 927 RPGLIPQAPG-----PRFPLIQPGIPPQRGIPPPSVLDSALHPPPRGP---------FPP 972
               +P  P          L  P +       P   L     PPP+ P          PP
Sbjct: 311 SLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPP 370

Query: 973 GDIFSQPERPFLAPGRQS 990
               S P  P   P  Q+
Sbjct: 371 SPPASPPLSPLATPSPQA 388


>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
           containing B [Homo sapiens]
          Length = 546

 Score = 64.7 bits (156), Expect = 5e-10
 Identities = 49/151 (32%), Positives = 77/151 (50%), Gaps = 19/151 (12%)

Query: 345 SPSQGSSQQHFLEPEVNLDDSIDIQQQDMDIDEGQDGVEEEVFEQEAKKVAVRSRSRTHS 404
           SP +  S+ H  E   +   S D   ++++ ++ +  +E E  E+E ++   RS  R   
Sbjct: 272 SPRRSRSRSHHREGHGS--SSFD---RELEREKERQRLEREAKEREKERRRSRSIDRGLE 326

Query: 405 RSRSRSPRKRRSRSRSGSRK--RKHRKRSRSRSRERKRKSSRSYSSER-RAREREKERQK 461
           R RSRS  + RSRSRS  RK  R+ R R R +  ER R+  R Y  ER   RE+E+ER +
Sbjct: 327 RRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSR 386

Query: 462 KGLPPIRSKTLSVCSTTLWVGQVDKKATQQD 492
           +     RS+           G+V++K  ++D
Sbjct: 387 ERSKEQRSR-----------GEVEEKKHKED 406



 Score = 50.8 bits (120), Expect = 8e-06
 Identities = 30/79 (37%), Positives = 41/79 (51%), Gaps = 4/79 (5%)

Query: 388 EQEAKKVAVRSRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRKRSRSRS---RERKRKSSR 444
           E E KK       R H R   R  +K +  SRS SR+RKHR RSRSR+   R R R   +
Sbjct: 397 EVEEKKHKEDKDDRRH-RDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEK 455

Query: 445 SYSSERRAREREKERQKKG 463
           S   +  ++E+  +R + G
Sbjct: 456 SSKHKNESKEKSNKRSRSG 474



 Score = 50.8 bits (120), Expect = 8e-06
 Identities = 34/103 (33%), Positives = 56/103 (54%), Gaps = 7/103 (6%)

Query: 366 IDIQQQDMDIDEGQDGVEEEVFEQEAKKVAVRSRSRTH-SRSRSRSPRKRRSRSRSGSRK 424
           ++ ++   D D+ +   ++   ++E K    RSR R H SRSRSR+  KR SRSRS  + 
Sbjct: 398 VEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKR-SRSRSKEKS 456

Query: 425 RKHRKRSRSRSRERKRKSSRSYS-----SERRAREREKERQKK 462
            KH+  S+ +S +R R  S+  +     S++R     KE+ +K
Sbjct: 457 SKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRK 499



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 42/116 (36%), Positives = 60/116 (51%), Gaps = 16/116 (13%)

Query: 361 NLDDSIDIQQQDMDIDEGQDGVEEEVFEQEAKKVAVRSRSRTHSRSRSRSPRKRRSRSRS 420
           N+D  I  + + +  D G++G EE     E +    RSRS   S S  RSPR+ RSRS  
Sbjct: 228 NIDQQIKTRPRKIKKD-GKEGAEEIDRHVERR----RSRSPRRSLSPRRSPRRSRSRSH- 281

Query: 421 GSRKRKHRKRSRSRSRERKRKSSRSYSSERRAREREKERQK-----KGLPPIRSKT 471
              +  H   S  R  ER+++  R    ER A+EREKER++     +GL   RS++
Sbjct: 282 --HREGHGSSSFDRELEREKERQRL---EREAKEREKERRRSRSIDRGLERRRSRS 332



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 33/97 (34%), Positives = 51/97 (52%), Gaps = 7/97 (7%)

Query: 369 QQQDMDIDEGQDGVEEEVFEQEAKKVAVRSRSRTHSRSRS--RSPRKRRSRSRSGSRKRK 426
           + +D D + G +  +E    +E  K   RSR     +     +  R+ R   R   +++K
Sbjct: 366 RDRDYDKERGNEREKERERSRERSKEQ-RSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKK 424

Query: 427 HRKRSRSRSRERKRKS-SRSYSSERRAREREKERQKK 462
           H   SRSRSRERK +S SRS ++ +R+R R KE+  K
Sbjct: 425 H---SRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSK 458



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 43/132 (32%), Positives = 61/132 (46%), Gaps = 15/132 (11%)

Query: 341 EHSASPSQGSSQQHFLEPEVNLDDSIDIQQQDMDIDEGQDGVEEEVFEQEAKKVAVRSRS 400
           E S   S+    +  +E + + +D  D + +D   D  ++        +E K    RSRS
Sbjct: 383 ERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKH---RSRS 439

Query: 401 RTHS---RSRSRSPRKRRSRSRSGSRKRKHRKRSRSRSR------ERKRKSSRSYSSER- 450
           R+ +   RSRSRS  K +S       K K  KRSRS S+      E+ +K   S S E+ 
Sbjct: 440 RSRNAGKRSRSRS--KEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKS 497

Query: 451 RAREREKERQKK 462
           R R R KER  K
Sbjct: 498 RKRSRSKERSHK 509



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 28/84 (33%), Positives = 42/84 (50%), Gaps = 5/84 (5%)

Query: 383 EEEVFEQEAKKVAVRSRSRTHS----RSRSRSPRKRRSRSRSGSRKRKHRKRSRSRSRER 438
           + E  E+  K+    S+ RT S    + R  SP K +SR RS S++R H KR  S S+++
Sbjct: 460 KNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSH-KRDHSDSKDQ 518

Query: 439 KRKSSRSYSSERRAREREKERQKK 462
             K  R  S       +EK+ + K
Sbjct: 519 SDKHDRRRSQSIEQESQEKQHKNK 542



 Score = 34.3 bits (77), Expect = 0.78
 Identities = 35/173 (20%), Positives = 76/173 (43%), Gaps = 19/173 (10%)

Query: 274 EHSEEPKKEIPASQLSHVSESVNNSIFHQIAEQLQQQNLEHLRQQLLEQQQPQKATPQDS 333
           E S+E +      +  H  +  +    H+  ++  ++  +H R +  E++   ++  +++
Sbjct: 387 ERSKEQRSRGEVEEKKHKEDKDDRR--HRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNA 444

Query: 334 QEGTFGSEHSASPSQGSSQQHFLEPEVNLDDSIDIQQQDMDIDEGQDGVEEEVFEQEAKK 393
                  + S S S+  S +H  E +         ++ +     G  G  + V E+  K+
Sbjct: 445 ------GKRSRSRSKEKSSKHKNESK---------EKSNKRSRSGSQGRTDSV-EKSKKR 488

Query: 394 VAVRSRSRTHSRSRSRSPRKRRSRSRSGSRKRKH-RKRSRSRSRERKRKSSRS 445
               S+ ++  RSRS+    +R  S S  +  KH R+RS+S  +E + K  ++
Sbjct: 489 EHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQHKN 541


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 64.3 bits (155), Expect = 7e-10
 Identities = 108/451 (23%), Positives = 138/451 (30%), Gaps = 53/451 (11%)

Query: 636  PPVAMLQIPVA-PAVPTV--SLVPPAFPVSMPVPPPGFSPIPPPPFLRASFNPSQPP--P 690
            PP A    P   PA P+   +  PPA     P   P  +P P       +  P  P   P
Sbjct: 988  PPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSP 1047

Query: 691  GFMPPPVPPPVVPPPTIP-----PVVPTSLVQPSL-SMTPETVKDVGFGSLVIPGGSVAS 744
               P P   P  P  T+P     P  P+    P+  + TP + K  G  +   P G+   
Sbjct: 1048 AATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPK--GGPATPSPKGAPMP 1105

Query: 745  NLATSALPAGNVFNAP------TKQAEPEEKVPHLIDHQISSGENTRSVIPNDISSNAAI 798
              AT   P G +   P      T  A P      L          T +  P    S    
Sbjct: 1106 PAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATP---PSPKGG 1162

Query: 799  LGGQPPNVTSNSGILGVQRPNVSSNSEILGVRPSNVSSSSGIIAAQPPNILNNSGILGIQ 858
            L   PP     +       P  +  S   G+   +   +    AA PP+        G+ 
Sbjct: 1163 LATPPPKGAPTT-------PAATPPSPKGGLATPSPKGAPTTPAATPPSPKG-----GLA 1210

Query: 859  PPSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGLLGTQPPAGPQNLPPLSIPNQRM 918
             PS   +       PP+     GL    P   P TP      P  GP   PP   P    
Sbjct: 1211 TPSPKGAPTTPAATPPS--PKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPA 1268

Query: 919  PTMPMLDIRPGLIPQAPGPRFPLIQPGIP-------PQRGIP------PPSVLDSALHPP 965
             T P L       P    P   ++ P  P       P +G P      PPS   S   PP
Sbjct: 1269 ATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPP 1328

Query: 966  PRG-PFPPGDIFSQPERPFLAPGR--QSVDNVTNP-EKRIPLGNDNIQQEGDRDYRFPPI 1021
            P+G P PP      P+     P     S    T P  K  P                PP 
Sbjct: 1329 PKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPS 1388

Query: 1022 ETRESISRPPPVDVRDVVGRPIDPREGPGRP 1052
              R      P  D       P+ P++ P  P
Sbjct: 1389 PKRGPAIPSPKGDPTSPAVIPLSPKKAPATP 1419



 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 119/504 (23%), Positives = 140/504 (27%), Gaps = 111/504 (22%)

Query: 630  QAEVFPPPVAMLQIPVAPAVPTVSLVPPAFPVSMPVPP-PGFSPIPP---PPFLRASFNP 685
            +A   P P  +   P     PT     P  P   P  P P ++P PP   PP  +     
Sbjct: 920  KARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPAT 979

Query: 686  SQP-----PPGFMPP--------------PVPPPVVPPPTIPPVVPTSLVQPSLSMTPET 726
              P     PP   PP              P PP V PP   P   P +   P  + TP  
Sbjct: 980  PSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPS--PKGSPAATPFPKGASTPPA 1037

Query: 727  VKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDHQISSGENTRS 786
                       P GS A+       P       P+ +  P    P L            S
Sbjct: 1038 ATPPS------PKGSPAATPLPKGAPTTPAATLPSPKGGP--ATPSLKGAPTPPAATPPS 1089

Query: 787  VIPNDISSNAAILGG-QPPNVTSNSGILGVQRPNVSSNSEILGVRPSNVSSSSGIIAAQP 845
              P    +  +  G   PP  T  S   G+  P            P    S  G +A  P
Sbjct: 1090 --PKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATP---PSPKGGLATPP 1144

Query: 846  PNIL---------NNSGILGIQPPS----------VSNSSGLLGVLPPNIPN-------- 878
            P            +  G L   PP            S   GL    P   P         
Sbjct: 1145 PKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPS 1204

Query: 879  -NSGLVGVQPPNVPNTPGLLGTQPPAGPQNLPPLSIPNQRMPTMPMLDIRPGLIPQAPGP 937
               GL    P   P TP      P  G     P   P     T P     P   P    P
Sbjct: 1205 PKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAP 1264

Query: 938  RFPLIQP-------GIPPQRGIPPPSVL-------DSALHPPPRGPFPPGDIFSQPERPF 983
              P   P         PP +G P P+V+         A  PP   P PP    + P  P 
Sbjct: 1265 TPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPA---ATPPSPK 1321

Query: 984  LAPGRQSVDNVTNPEKRIPLGNDNIQQEGDRDYRFPPIETRESISRPP--PVDVRDVVGR 1041
             +PG       T P K  P                PP  T  S    P  P       G 
Sbjct: 1322 GSPG-------TPPPKGAPT---------------PPAVTPPSPKGTPTLPATTPSSKGG 1359

Query: 1042 PIDP--REGPGRPPLDGRDHFGRP 1063
            P  P  +EGP  PP     H G P
Sbjct: 1360 PTTPSSKEGP-TPPAATPSHKGGP 1382



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 110/464 (23%), Positives = 167/464 (35%), Gaps = 69/464 (14%)

Query: 619  TPVEKETVVT-TQAEVFPPPVAMLQIPVAPAVPTVSLVPPAFPVSMPVP------PPGFS 671
            TPV +E   T ++ ++ PP V  + +  APA  +     PA P S   P      PP   
Sbjct: 1418 TPVTREGAATPSKGDLTPPAVTPVSLKKAPAT-SAPKGGPATPSSKGDPTLPAVTPPSPK 1476

Query: 672  PIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPP--PTIPPVVPTS------LVQPSLSM- 722
              P P  +  S +P + P    P P+  P +P   P+ P  VP +       + P+ ++ 
Sbjct: 1477 EPPAPKQVATSSSPKKAPA--TPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLL 1534

Query: 723  ---TPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDHQIS 779
               TP T+      +L+ P  +V S   T A+P      AP   +  E   P  +     
Sbjct: 1535 SKKTPATLAPK--EALIPPAMTVPSPKKTPAIPTPK--EAPATPSSKEASSPPAVTPSTY 1590

Query: 780  SGENT--RSVIPNDISSNAAILGGQPPNVTSNSGILGVQRPNVSSNSEILGVRPSNVSSS 837
             G  +    +IP  ++S +      PP VT  S   G   P          V PS++  S
Sbjct: 1591 KGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDS 1650

Query: 838  SGIIAAQPPNILNNSGILGIQP----PSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVPNT 893
                   P ++    G    Q     P+    + L  VL    P ++ ++       P T
Sbjct: 1651 ----PTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQT 1706

Query: 894  PGLLGTQPPAGPQNLPPLSIPNQRMPTMPMLDIRPGLIPQAPGPRFPLIQPGIPPQRGIP 953
                 T PP  P    P +    + P          L   AP P  P+ +      +G  
Sbjct: 1707 KKSSATSPPICPD---PSAKNGSKGP----------LSTVAPAPLLPVQKDSSKTAKG-- 1751

Query: 954  PPSVLDSALHPPPRGPF-PPGDIFSQP------ERPFLAPGRQSVDNVTNPEKRIPLGND 1006
                   A H  P+GP  PP    S P      E+    P   SV    +P   +PL   
Sbjct: 1752 -----KDASH-SPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPS 1805

Query: 1007 NIQQEGDRDYRFP--PIETRESISRP-PPVDVRDVVGRPIDPRE 1047
             +     +    P  P    ES S+P  P D  +++  P+ P E
Sbjct: 1806 PVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELL--PLIPPE 1847



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 103/438 (23%), Positives = 145/438 (33%), Gaps = 98/438 (22%)

Query: 600  ETVKSSEPVKETVQTTQSPTPVEKETVVTTQAEVFPPPVAMLQIPVAPAV---------- 649
            +   SS P K          P     + ++  EV P   +  + P+AP            
Sbjct: 1483 QVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEV-PATPSSRRDPIAPTATLLSKKTPAT 1541

Query: 650  --PTVSLVPPAFPVSMP-----VPPPGFSPIPP-------PPFLRASFNPSQPPPG--FM 693
              P  +L+PPA  V  P     +P P  +P  P       PP +  S     P P    +
Sbjct: 1542 LAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLI 1601

Query: 694  PP----------PVPPPVVPP--------------PTIPPVVPTSLVQPSLSMTPETVKD 729
            PP          P PP V PP              PT PPV P+SL     S    T K 
Sbjct: 1602 PPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCK- 1660

Query: 730  VGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDHQISSGENTRSVIP 789
                   +P  S              V  AP  ++ P      +I      G  T+    
Sbjct: 1661 ---MGATVPQASKGLPAKKGPTALKEVLVAPAPESTP------IITAPTRKGPQTKK--- 1708

Query: 790  NDISSNAAILGGQPPNVTSNSGILGVQRPNVSSNSEILGVRPSNVSSSSGIIAAQPPNIL 849
               S+ +  +   P     + G L    P     + +L V+  +  ++ G  A+  P   
Sbjct: 1709 --SSATSPPICPDPSAKNGSKGPLSTVAP-----APLLPVQKDSSKTAKGKDASHSP--- 1758

Query: 850  NNSGILGIQPPSVSNSSGLLG-----VLPPNIPNNSGLVGVQPPNVPNTPGLLGTQPPAG 904
               G L   PP    S+ L       VLP   P ++ +     P V           P  
Sbjct: 1759 --KGPLA--PPESKASTPLTAAAFEKVLPK--PESASVSAAPSPPV---------SLPLA 1803

Query: 905  PQNLPPLSIPNQRMPTMPMLDIRPGLIPQAPGPRFPLIQPGIPPQ---RGIPPPSVLDSA 961
            P  +P L    Q +P+ P L +     P AP     L+ P IPP+    G+P  SVL + 
Sbjct: 1804 PSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELL-PLIPPEPISGGVPFQSVLVNM 1862

Query: 962  LHPPPRGPFPPGDIFSQP 979
              P   G   P     QP
Sbjct: 1863 PTPKSAGIPVPTPSAKQP 1880



 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 104/455 (22%), Positives = 143/455 (31%), Gaps = 64/455 (14%)

Query: 628  TTQAEVFPPPVAMLQIPVAPAVPTVSLVPPAFPVSMPV-PPPGFSPIPP---PPFLRASF 683
            TT A   P P   L  P     PT     P  P   P  PPP  +P PP   PP L+   
Sbjct: 1219 TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGL 1278

Query: 684  NPSQPPPGFMPPPVPPPVVP------PPTIPP---VVPTSLVQPSLSMTPETVKDVGFGS 734
                  P     P P  V P      P T PP     P +   PS   +P T      G+
Sbjct: 1279 ----ATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPK--GA 1332

Query: 735  LVIPGGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDHQISSGENTRSVIPNDISS 794
               P  +  S   T  LPA      P+ +  P            SS E      P   ++
Sbjct: 1333 PTPPAVTPPSPKGTPTLPA----TTPSSKGGPTTP---------SSKEG-----PTPPAA 1374

Query: 795  NAAILGGQPPNVTSNSGILGVQRPNVSSNSEILGVRPSNVSSSSGIIAAQPPNILNNSGI 854
              +  GG  P +T  S   G   P+   +     V P +   +      +      + G 
Sbjct: 1375 TPSHKGG--PAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKG- 1431

Query: 855  LGIQPPSV---------SNSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGLLGTQPPAGP 905
              + PP+V         + S+   G   P+   +  L  V PP+    P        + P
Sbjct: 1432 -DLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSP 1490

Query: 906  QNLPPLSIPNQRMPTMP-MLDIRPGLIPQAPGPRFPLIQPGIPPQRGIPPPSVLDSALHP 964
            +  P    P    PT+P ++   P  +P  P  R   I P         P ++       
Sbjct: 1491 KKAPATPAP-MGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALI 1549

Query: 965  PPRGPFPPGDIFSQPERPFLAPGRQSVDNVTNPEKRIPLGNDNIQQEGDRDYRFPPIETR 1024
            PP    P          P  AP   S    ++P    P  +        ++   PP  T 
Sbjct: 1550 PPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTP--STYKGAPSPKELLIPPAVTS 1607

Query: 1025 ES---ISRPPPVDVRDVVGRPIDPREGPGRPPLDG 1056
             S      PP V        P  P +GP  P   G
Sbjct: 1608 PSPKEAPTPPAV-------TPPSPEKGPATPAPKG 1635



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 85/388 (21%), Positives = 150/388 (38%), Gaps = 78/388 (20%)

Query: 624 ETVVTTQAEVFPPPVAMLQIPVAPAV--------PTVSLVPPAFPVSMPVPPPG---FSP 672
           ETV  T+ E+  P      +P++ A+        P  +L PP  P     P       SP
Sbjct: 7   ETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASP 66

Query: 673 IPPP----------PFLRASFNPSQP------PPGFMPPPVPPPVVPPP---TIPPVVPT 713
            P P          PF ++S   + P       P F+P  + PP+ P       P + PT
Sbjct: 67  FPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPT 126

Query: 714 SLVQPS-------LSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNV--FNAPTKQA 764
               PS       +++ P +V+     S   P   + S  + +   +G+V   +AP   +
Sbjct: 127 LKGTPSSSAPLALVALAPHSVQK----SSAFPPNLLTSPPSVAVAESGSVITLSAPIAPS 182

Query: 765 EPEEKVPHLIDHQISSGENTRSVIPNDISSNAAILGGQPPNVTSNSGILGVQRPNVSSNS 824
           EP+  +  +    + + + T S  P  I S         P  +  SG+  + +   ++  
Sbjct: 183 EPKTNLNKVPSEVVPNPKGTPS--PPCIVSTVP-YHCVTPMASIQSGVASLPQTTPTTTL 239

Query: 825 EILGVRPSNVSSSSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLGVL-----------P 873
            I   +  + + SS +I+ Q P  L+  G +   P ++S S+  L V+           P
Sbjct: 240 AIASPQVKDTTISSVLISPQNPGSLSLKGPVS-PPAALSLSTQSLPVVTSSQKTAGPNTP 298

Query: 874 PNIPNNSG---------------LVGVQPPNVPNTPGLLGTQPPAGPQNLPPLSIPNQRM 918
           P+ P + G               L+G   P+  + P +   +  +   +    S P+QR 
Sbjct: 299 PDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTV---KTISVDHSSTGASYPSQR- 354

Query: 919 PTMPMLDIRPGLIPQAPGPRFPLIQPGI 946
             +P L  R  ++P A    FP++ P +
Sbjct: 355 SVIPPLPSRNEVVP-ATVAAFPVVAPSV 381



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 96/434 (22%), Positives = 144/434 (33%), Gaps = 82/434 (18%)

Query: 607  PVKETVQTTQSPTPVE-KETVVTTQAEVFPPPVAM--------LQIPVAPAVPTVSLVPP 657
            P  +   TT + TP   K    T   +  P P A         L  P     P  ++V P
Sbjct: 1235 PSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTP 1294

Query: 658  AFPVSMPVP-PPGFSPIPP---PPFLRASFNPSQPPPGFMPPPVPPPVVPP-----PTIP 708
              P   P   PP  +P PP   PP  + S  P  PPP     P PP V PP     PT+P
Sbjct: 1295 PSPKGGPATSPPKGAPTPPAATPPSPKGS--PGTPPP--KGAPTPPAVTPPSPKGTPTLP 1350

Query: 709  ---------PVVPTSLVQPSLSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNA 759
                     P  P+S   P+    P        G  + P          S  P G+  + 
Sbjct: 1351 ATTPSSKGGPTTPSSKEGPT---PPAATPSHKGGPAMTPPSPKRGPAIPS--PKGDPTSP 1405

Query: 760  PTKQAEPEEKVPHLIDHQISSGENTRSVIPNDISSNAAILGGQPPNVTSNSGILGVQRPN 819
                  P++     +  + ++  +   + P  ++    +   + P  ++  G  G   P+
Sbjct: 1406 AVIPLSPKKAPATPVTREGAATPSKGDLTPPAVT---PVSLKKAPATSAPKG--GPATPS 1460

Query: 820  VSSNSEILGVRPSNVSSSSGIIAAQPPNILNNSGILGIQPPSVSNSSGLLG--VLPPNIP 877
               +  +  V P +           P  +  +S      P     +   +G   LP  IP
Sbjct: 1461 SKGDPTLPAVTPPSPKEPPA-----PKQVATSS-----SPKKAPATPAPMGAPTLPAVIP 1510

Query: 878  NNSGLVGVQP-----PNVP-------NTPGLLGTQ----PPA----GPQNLPPLSIPNQR 917
            ++   V   P     P  P        TP  L  +    PPA     P+  P +  P + 
Sbjct: 1511 SSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEA 1570

Query: 918  MPTMPMLD------IRPGLIPQAPGPRFPLIQPGI---PPQRGIPPPSVLDSALHPPPRG 968
              T    +      + P     AP P+  LI P +    P+    PP+V   +    P  
Sbjct: 1571 PATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPAT 1630

Query: 969  PFPPGDIFSQPERP 982
            P P G   S P  P
Sbjct: 1631 PAPKGTPTSPPVTP 1644



 Score = 38.9 bits (89), Expect = 0.032
 Identities = 92/420 (21%), Positives = 139/420 (33%), Gaps = 51/420 (12%)

Query: 576  VKVDDLEGFAEGGMIDQETVNTEWETVKSSEPVKETVQTTQSPTPVEKETVVTTQAEVFP 635
            +K D   G    G + + ++ T      ++ P++       +PT  +  +  TT A  F 
Sbjct: 621  IKTDSYAGPDSAGPLLKSSLITP---TVAAFPLESADPAGVAPTTAKGTSTYTTTASPFL 677

Query: 636  P----------PVAMLQIPVAPAVPTVSLVPPAFPVSMPVPPPGFSPIPPPPFLRASFNP 685
                       PV    +   P VPT S   P  P       P  + +  P   ++  +P
Sbjct: 678  EGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSP 737

Query: 686  SQPPPGFMPPPVPPPVVPPPT--IPPVVPTSLVQPSLSMTPETVKDVGFGSLVIPGGSVA 743
            S PP G           PP T  +  +  TS + P  S   E   +    S         
Sbjct: 738  SLPPAG----------TPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTL 787

Query: 744  SNLATSALPAGNVFNAPTKQAEPEEKVPHLIDHQISSGENTRSVIPNDIS----SNAAIL 799
            + LA S  P G V  +P  +  P +K     D  I  G  +  V P + S    ++ +  
Sbjct: 788  TYLADSPSPLG-VSVSPQTKRPPTKKGSAGPDTPI--GNLSSPVSPVEASFLPENSLSFQ 844

Query: 800  GGQPPNVTSNSGILGVQRPNVSSNSEILGVRPSNVSSSSGIIAAQPPNILNNSGILGIQP 859
            G +    T++S       P   S        PS V+  S      PP       ++ +  
Sbjct: 845  GSKDSPATTHS-------PTPPSPKG--APTPSAVTPLSPKGVTLPPKETPTPSVVNLPF 895

Query: 860  PSVSNSSGLLGVLPPNIPNNSGLVGVQ----PPNVPNTPGLLGTQPPAGPQNLPPLSIPN 915
            P    ++      P     +S     +    P  +P +P   G   P  P   PP     
Sbjct: 896  PKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGA--PTPPAATPPSPKGG 953

Query: 916  QRMPTMPMLDIRPGLIPQAP--GPRFPLIQPGIPPQRGIPPPSVLDSALHPPPRG-PFPP 972
               P+       P   P +P  GP  P    G P      PPS       P P+G P PP
Sbjct: 954  PATPSPKWAPTPPAATPPSPKGGPATP-SPKGAPTPPAATPPSPKGGPATPSPKGAPTPP 1012



 Score = 37.0 bits (84), Expect = 0.12
 Identities = 70/338 (20%), Positives = 114/338 (33%), Gaps = 60/338 (17%)

Query: 658 AFPVSMPVPPPGFS------------PIPPP-PFLRASFNPSQPPPGFMPPPVPPPVVPP 704
           AFP ++   PP  +            PI P  P    +  PS+  P     P PP +V  
Sbjct: 152 AFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVST 211

Query: 705 PTIPPVVPTSLVQPSLSMTPET------------VKDVGFGSLVIPGGSVASNLATSALP 752
                V P + +Q  ++  P+T            VKD    S++I      S     +L 
Sbjct: 212 VPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLI------SPQNPGSLS 265

Query: 753 AGNVFNAPTKQAEPEEKVPHLIDHQISSGENTRSVIPNDISSNAA-----------ILGG 801
                + P   +   + +P +   Q ++G NT    P  + S+ A           +LG 
Sbjct: 266 LKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQ 325

Query: 802 QPPNVTSNSGILGVQRPNVS------SNSEILGVRPSNVSSSSGIIAAQPPNILNNSGIL 855
             P+  S+  +  +   + S      S   ++   PS        +AA P          
Sbjct: 326 TGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFP---------- 375

Query: 856 GIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGLLGTQPPAGPQNLPPLSIPN 915
            +  PSV      +  +  + P+ S  V       P T  +L + P A         +P 
Sbjct: 376 -VVAPSVDKGPSTISSITCS-PSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPV 433

Query: 916 QRMPTMPMLDIRPGLIPQAPGPRFPLIQPGIPPQRGIP 953
             + T P++   P  I  AP   F +     PP    P
Sbjct: 434 SSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGP 471


>gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sapiens]
          Length = 2603

 Score = 64.3 bits (155), Expect = 7e-10
 Identities = 81/337 (24%), Positives = 121/337 (35%), Gaps = 34/337 (10%)

Query: 652  VSLVPPAFPVSMPVPPPGFSPIPPPPFLRA-----SFNPSQPPP------GFMPPPVPPP 700
            V+ V P FPVS+P+        PPP F  A     +F   +PP       G   PP    
Sbjct: 1870 VNNVRPGFPVSLPL------AYPPPQFAHALLAAQTFQQIRPPRLPMTHFGGTFPPAQST 1923

Query: 701  VVPPPTIPPVVPTSLVQPSLSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAP 760
              P P  P     +   P   M P        GS V   GS+ S+  T+   + +     
Sbjct: 1924 WGPFPVRPLSPARATNSPKPHMVPRHSNQNSSGSQVNSAGSLTSSPTTTTSSSASTVPGT 1983

Query: 761  TKQAEPEEKVPHLIDHQISSGENTRSVIPNDISSNAAILGGQPPNVTSNSGILGVQRPNV 820
            +    P    P +      +   T +     +++ A+     P N T          P  
Sbjct: 1984 STNGSPSS--PSVRRQLFVTVVKTSNATTTTVTTTASNNNTAPTNATYPMPTAKEHYPVS 2041

Query: 821  SSNSEILGVRPSNVSSSSGII--AAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPN 878
            S +S     +P  VS +S +   +A P  + ++S      PP V  ++      PPN  +
Sbjct: 2042 SPSSPSPPAQPGGVSRNSPLDCGSASPNKVASSSEQEAGSPPVVETTN----TRPPNSSS 2097

Query: 879  NSGLVGVQPPNVPNTPGLLGTQ--PPAGPQNLPPLSIPNQRMPTMPM-LDIRPGLIPQAP 935
            +SG       N    PG +  +  PP     +PP   P  RM   P+     P  +P   
Sbjct: 2098 SSGSSSAH-SNQQQPPGSVSQEPRPPLQQSQVPP---PEVRMTVPPLATSSAPVAVPSTA 2153

Query: 936  GPRFPLIQPGIPPQRGIPPPSVLDSALHPPPRGPFPP 972
               +P+  P  P     P P +   A+ PPP G   P
Sbjct: 2154 PVTYPM--PQTPMGCPQPTPKMETPAIRPPPHGTTAP 2188



 Score = 40.0 bits (92), Expect = 0.014
 Identities = 92/366 (25%), Positives = 130/366 (35%), Gaps = 73/366 (19%)

Query: 593  ETVNTEWETVKSSEPVKETVQTTQSPT-PVEKETVVTTQAEVFPPPVAMLQIPVAPAVPT 651
            ET NT      SS          Q P   V +E     Q    PPP   + +P       
Sbjct: 2086 ETTNTRPPNSSSSSGSSSAHSNQQQPPGSVSQEPRPPLQQSQVPPPEVRMTVPPLATSSA 2145

Query: 652  VSLVPPAFPVSMPVP-PPGFSPIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPPPTI--- 707
               VP   PV+ P+P  P   P P P     +  P  PP G   P      V   ++   
Sbjct: 2146 PVAVPSTAPVTYPMPQTPMGCPQPTPKMETPAIRP--PPHGTTAPHKNSASVQNSSVAVL 2203

Query: 708  -------PPVVPTSLVQPSLSMTPETVKDVGFGSLVIPGGSVASNLATSALPAG---NVF 757
                   P  VP+S+  PS   T    +     + V P     +   ++ LP G    +F
Sbjct: 2204 SVNHIKRPHSVPSSVQLPSTLSTQSACQ-----NSVHPANKPIAPNFSAPLPFGPFSTLF 2258

Query: 758  -NAPT------------KQAEPEEKVPHLIDHQISSGENTRSVIPND----ISSNAAILG 800
             N+PT             Q+ PE  +         SG++  S +PN      S  +   G
Sbjct: 2259 ENSPTSAHAFWGGSVVSSQSTPESML---------SGKS--SYLPNSDPLHQSDTSKAPG 2307

Query: 801  GQPP---NVTSNSGILGVQRP--NVSSNSEILGVRPSNVSSS---------SGIIAAQPP 846
             +PP      S SGI+ +  P  +V+ +S  LG   SN+S            G  AA   
Sbjct: 2308 FRPPLQRPAPSPSGIVNMDSPYGSVTPSSTHLGNFASNISGGQMYGPGAPLGGAPAAANF 2367

Query: 847  NILNNSGILGIQP-PSVSNSSGLLGV-----LPPNIPNNSGLVGVQPPNVP---NTPGLL 897
            N  + S +  + P  S SN S    V      P   P++  L   +P NV      P  +
Sbjct: 2368 NRQHFSPLSLLTPCSSASNDSSAQSVSSGVRAPSPAPSSVPLGSEKPSNVSQDRKVPVPI 2427

Query: 898  GTQPPA 903
            GT+  A
Sbjct: 2428 GTERSA 2433


>gi|38683816 ankyrin repeat domain protein 17 isoform b [Homo sapiens]
          Length = 2352

 Score = 64.3 bits (155), Expect = 7e-10
 Identities = 81/337 (24%), Positives = 121/337 (35%), Gaps = 34/337 (10%)

Query: 652  VSLVPPAFPVSMPVPPPGFSPIPPPPFLRA-----SFNPSQPPP------GFMPPPVPPP 700
            V+ V P FPVS+P+        PPP F  A     +F   +PP       G   PP    
Sbjct: 1619 VNNVRPGFPVSLPL------AYPPPQFAHALLAAQTFQQIRPPRLPMTHFGGTFPPAQST 1672

Query: 701  VVPPPTIPPVVPTSLVQPSLSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAP 760
              P P  P     +   P   M P        GS V   GS+ S+  T+   + +     
Sbjct: 1673 WGPFPVRPLSPARATNSPKPHMVPRHSNQNSSGSQVNSAGSLTSSPTTTTSSSASTVPGT 1732

Query: 761  TKQAEPEEKVPHLIDHQISSGENTRSVIPNDISSNAAILGGQPPNVTSNSGILGVQRPNV 820
            +    P    P +      +   T +     +++ A+     P N T          P  
Sbjct: 1733 STNGSPSS--PSVRRQLFVTVVKTSNATTTTVTTTASNNNTAPTNATYPMPTAKEHYPVS 1790

Query: 821  SSNSEILGVRPSNVSSSSGII--AAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPN 878
            S +S     +P  VS +S +   +A P  + ++S      PP V  ++      PPN  +
Sbjct: 1791 SPSSPSPPAQPGGVSRNSPLDCGSASPNKVASSSEQEAGSPPVVETTN----TRPPNSSS 1846

Query: 879  NSGLVGVQPPNVPNTPGLLGTQ--PPAGPQNLPPLSIPNQRMPTMPM-LDIRPGLIPQAP 935
            +SG       N    PG +  +  PP     +PP   P  RM   P+     P  +P   
Sbjct: 1847 SSGSSSAH-SNQQQPPGSVSQEPRPPLQQSQVPP---PEVRMTVPPLATSSAPVAVPSTA 1902

Query: 936  GPRFPLIQPGIPPQRGIPPPSVLDSALHPPPRGPFPP 972
               +P+  P  P     P P +   A+ PPP G   P
Sbjct: 1903 PVTYPM--PQTPMGCPQPTPKMETPAIRPPPHGTTAP 1937



 Score = 40.0 bits (92), Expect = 0.014
 Identities = 92/366 (25%), Positives = 130/366 (35%), Gaps = 73/366 (19%)

Query: 593  ETVNTEWETVKSSEPVKETVQTTQSPT-PVEKETVVTTQAEVFPPPVAMLQIPVAPAVPT 651
            ET NT      SS          Q P   V +E     Q    PPP   + +P       
Sbjct: 1835 ETTNTRPPNSSSSSGSSSAHSNQQQPPGSVSQEPRPPLQQSQVPPPEVRMTVPPLATSSA 1894

Query: 652  VSLVPPAFPVSMPVP-PPGFSPIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPPPTI--- 707
               VP   PV+ P+P  P   P P P     +  P  PP G   P      V   ++   
Sbjct: 1895 PVAVPSTAPVTYPMPQTPMGCPQPTPKMETPAIRP--PPHGTTAPHKNSASVQNSSVAVL 1952

Query: 708  -------PPVVPTSLVQPSLSMTPETVKDVGFGSLVIPGGSVASNLATSALPAG---NVF 757
                   P  VP+S+  PS   T    +     + V P     +   ++ LP G    +F
Sbjct: 1953 SVNHIKRPHSVPSSVQLPSTLSTQSACQ-----NSVHPANKPIAPNFSAPLPFGPFSTLF 2007

Query: 758  -NAPT------------KQAEPEEKVPHLIDHQISSGENTRSVIPND----ISSNAAILG 800
             N+PT             Q+ PE  +         SG++  S +PN      S  +   G
Sbjct: 2008 ENSPTSAHAFWGGSVVSSQSTPESML---------SGKS--SYLPNSDPLHQSDTSKAPG 2056

Query: 801  GQPP---NVTSNSGILGVQRP--NVSSNSEILGVRPSNVSSS---------SGIIAAQPP 846
             +PP      S SGI+ +  P  +V+ +S  LG   SN+S            G  AA   
Sbjct: 2057 FRPPLQRPAPSPSGIVNMDSPYGSVTPSSTHLGNFASNISGGQMYGPGAPLGGAPAAANF 2116

Query: 847  NILNNSGILGIQP-PSVSNSSGLLGV-----LPPNIPNNSGLVGVQPPNVP---NTPGLL 897
            N  + S +  + P  S SN S    V      P   P++  L   +P NV      P  +
Sbjct: 2117 NRQHFSPLSLLTPCSSASNDSSAQSVSSGVRAPSPAPSSVPLGSEKPSNVSQDRKVPVPI 2176

Query: 898  GTQPPA 903
            GT+  A
Sbjct: 2177 GTERSA 2182


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.133    0.395 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 62,261,022
Number of Sequences: 37866
Number of extensions: 4022400
Number of successful extensions: 58814
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 678
Number of HSP's successfully gapped in prelim test: 1398
Number of HSP's that attempted gapping in prelim test: 19871
Number of HSP's gapped (non-prelim): 17675
length of query: 1271
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1157
effective length of database: 13,930,794
effective search space: 16117928658
effective search space used: 16117928658
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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