Guide to the Human Genome
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Search of human proteins with 61743942

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|61743942 abl-interactor 1 isoform a [Homo sapiens]
         (508 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|61743942 abl-interactor 1 isoform a [Homo sapiens]                1042   0.0  
gi|61743944 abl-interactor 1 isoform b [Homo sapiens]                 973   0.0  
gi|61743948 abl-interactor 1 isoform d [Homo sapiens]                 956   0.0  
gi|61743946 abl-interactor 1 isoform c [Homo sapiens]                 890   0.0  
gi|109689723 abl interactor 2 [Homo sapiens]                          692   0.0  
gi|7705981 NESH protein isoform 1 [Homo sapiens]                      207   2e-53
gi|206597502 NESH protein isoform 2 [Homo sapiens]                    197   1e-50
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]                 80   4e-15
gi|116284392 mucin 2 precursor [Homo sapiens]                          71   2e-12
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    69   8e-12
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    69   8e-12
gi|224586851 sorbin and SH3 domain containing 2 isoform 6 [Homo ...    66   7e-11
gi|224586846 sorbin and SH3 domain containing 2 isoform 4 [Homo ...    66   7e-11
gi|47132519 Ras association and pleckstrin homology domains 1 is...    66   7e-11
gi|194294523 intersectin 2 isoform 3 [Homo sapiens]                    65   1e-10
gi|194294521 intersectin 2 isoform 1 [Homo sapiens]                    65   1e-10
gi|194294525 intersectin 2 isoform 2 [Homo sapiens]                    65   1e-10
gi|112734870 hypothetical protein LOC57648 [Homo sapiens]              65   1e-10
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    64   3e-10
gi|46094081 development and differentiation enhancing factor 1 [...    64   3e-10
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    64   4e-10
gi|18959210 WIRE protein [Homo sapiens]                                63   6e-10
gi|153792074 proline rich 12 [Homo sapiens]                            63   6e-10
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho...    62   1e-09
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]                     62   2e-09
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]                     62   2e-09
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    61   2e-09
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]                 61   2e-09
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]                61   3e-09
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]                61   3e-09

>gi|61743942 abl-interactor 1 isoform a [Homo sapiens]
          Length = 508

 Score = 1042 bits (2695), Expect = 0.0
 Identities = 508/508 (100%), Positives = 508/508 (100%)

Query: 1   MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS 60
           MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS
Sbjct: 1   MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS 60

Query: 61  VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120
           VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR
Sbjct: 61  VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120

Query: 121 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK 180
           THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK
Sbjct: 121 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK 180

Query: 181 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS 240
           PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS
Sbjct: 181 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS 240

Query: 241 GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENISVPPPSGAPPAPPLAPLLPVSTVI 300
           GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENISVPPPSGAPPAPPLAPLLPVSTVI
Sbjct: 241 GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENISVPPPSGAPPAPPLAPLLPVSTVI 300

Query: 301 AAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSI 360
           AAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSI
Sbjct: 301 AAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSI 360

Query: 361 SIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVD 420
           SIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVD
Sbjct: 361 SIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVD 420

Query: 421 YEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKND 480
           YEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKND
Sbjct: 421 YEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKND 480

Query: 481 DGWYEGVCNRVTGLFPGNYVESIMHYTD 508
           DGWYEGVCNRVTGLFPGNYVESIMHYTD
Sbjct: 481 DGWYEGVCNRVTGLFPGNYVESIMHYTD 508


>gi|61743944 abl-interactor 1 isoform b [Homo sapiens]
          Length = 481

 Score =  973 bits (2516), Expect = 0.0
 Identities = 481/508 (94%), Positives = 481/508 (94%), Gaps = 27/508 (5%)

Query: 1   MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS 60
           MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS
Sbjct: 1   MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS 60

Query: 61  VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120
           VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR
Sbjct: 61  VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120

Query: 121 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK 180
           THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK
Sbjct: 121 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK 180

Query: 181 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS 240
           PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS
Sbjct: 181 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS 240

Query: 241 GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENISVPPPSGAPPAPPLAPLLPVSTVI 300
           GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGP                           
Sbjct: 241 GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGP--------------------------- 273

Query: 301 AAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSI 360
           AAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSI
Sbjct: 274 AAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSI 333

Query: 361 SIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVD 420
           SIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVD
Sbjct: 334 SIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVD 393

Query: 421 YEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKND 480
           YEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKND
Sbjct: 394 YEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKND 453

Query: 481 DGWYEGVCNRVTGLFPGNYVESIMHYTD 508
           DGWYEGVCNRVTGLFPGNYVESIMHYTD
Sbjct: 454 DGWYEGVCNRVTGLFPGNYVESIMHYTD 481


>gi|61743948 abl-interactor 1 isoform d [Homo sapiens]
          Length = 476

 Score =  956 bits (2471), Expect = 0.0
 Identities = 476/508 (93%), Positives = 476/508 (93%), Gaps = 32/508 (6%)

Query: 1   MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS 60
           MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS
Sbjct: 1   MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS 60

Query: 61  VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120
           VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR
Sbjct: 61  VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120

Query: 121 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK 180
           THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVK     HGNNQPARTGTLSRTNPPTQK
Sbjct: 121 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVK-----HGNNQPARTGTLSRTNPPTQK 175

Query: 181 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS 240
           PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS
Sbjct: 176 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS 235

Query: 241 GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENISVPPPSGAPPAPPLAPLLPVSTVI 300
           GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGP                           
Sbjct: 236 GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGP--------------------------- 268

Query: 301 AAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSI 360
           AAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSI
Sbjct: 269 AAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSI 328

Query: 361 SIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVD 420
           SIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVD
Sbjct: 329 SIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVD 388

Query: 421 YEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKND 480
           YEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKND
Sbjct: 389 YEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKND 448

Query: 481 DGWYEGVCNRVTGLFPGNYVESIMHYTD 508
           DGWYEGVCNRVTGLFPGNYVESIMHYTD
Sbjct: 449 DGWYEGVCNRVTGLFPGNYVESIMHYTD 476


>gi|61743946 abl-interactor 1 isoform c [Homo sapiens]
          Length = 452

 Score =  890 bits (2301), Expect = 0.0
 Identities = 448/508 (88%), Positives = 450/508 (88%), Gaps = 56/508 (11%)

Query: 1   MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS 60
           MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS
Sbjct: 1   MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS 60

Query: 61  VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120
           VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR
Sbjct: 61  VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120

Query: 121 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK 180
           THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK
Sbjct: 121 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK 180

Query: 181 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS 240
           PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS
Sbjct: 181 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS 240

Query: 241 GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENISVPPPSGAPPAPPLAPLLPVSTVI 300
           GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGP                           
Sbjct: 241 GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGP--------------------------- 273

Query: 301 AAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSI 360
           AAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSI
Sbjct: 274 AAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSI 333

Query: 361 SIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVD 420
           + +P P                             PPPPPPDDIPMFDDSPPPPPPPPVD
Sbjct: 334 ADSPTP-----------------------------PPPPPPDDIPMFDDSPPPPPPPPVD 364

Query: 421 YEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKND 480
           YEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKND
Sbjct: 365 YEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKND 424

Query: 481 DGWYEGVCNRVTGLFPGNYVESIMHYTD 508
           DGWYEGVCNRVTGLFPGNYVESIMHYTD
Sbjct: 425 DGWYEGVCNRVTGLFPGNYVESIMHYTD 452


>gi|109689723 abl interactor 2 [Homo sapiens]
          Length = 475

 Score =  692 bits (1785), Expect = 0.0
 Identities = 359/518 (69%), Positives = 408/518 (78%), Gaps = 53/518 (10%)

Query: 1   MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS 60
           MAELQMLLEEEIP G+RAL +SY NL RVADYCENNYIQ+ DK++ALEETKAYTTQSLAS
Sbjct: 1   MAELQMLLEEEIPGGRRALFDSYTNLERVADYCENNYIQSADKQRALEETKAYTTQSLAS 60

Query: 61  VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120
           VAY IN LANNVLQ+LDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR
Sbjct: 61  VAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120

Query: 121 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK 180
           THKIIAPAN+ERPVRYIRKPIDYT+LDD+GHGVK       + Q  + G L RT PPTQK
Sbjct: 121 THKIIAPANLERPVRYIRKPIDYTILDDIGHGVK------VSTQNMKMGGLPRTTPPTQK 174

Query: 181 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPAR--LGSQHSPGRTASLNQRPRT 238
           PPSPPMSG+GTLGR++PY+TLEPV+PP VPNDY+ SP R    SQ SP RTAS+NQR RT
Sbjct: 175 PPSPPMSGKGTLGRHSPYRTLEPVRPPVVPNDYVPSPTRNMAPSQQSPVRTASVNQRNRT 234

Query: 239 H--SGSSGG------SGSRENSGSSSIGIPIAVPTPSPPTIGPENISVPPPSGAPPAPPL 290
           +  SGSSGG      S SRENSGS S+G+PIAVPTPSPP++ P +               
Sbjct: 235 YSSSGSSGGSHPSSRSSSRENSGSGSVGVPIAVPTPSPPSVFPGH--------------- 279

Query: 291 APLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVN 350
               PV             Q+ +M R  SRH   T    S  YRR PS+T+Q S Q  +N
Sbjct: 280 ----PV-------------QFYSMNRPASRHTPPTIG-GSLPYRRPPSITSQTSLQNQMN 321

Query: 351 GGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDS 410
           GGP YSQN +S+APPPP + Q+TPQ+PL GFVARVQENI+D+   PPPPPP + P+FD+S
Sbjct: 322 GGPFYSQNPVSLAPPPPSILQVTPQLPLMGFVARVQENISDT---PPPPPPVEEPVFDES 378

Query: 411 PPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEG 470
           PPPPPPP  DYE+EEAAVV+Y+DPYA+ DP WAP++Y+EKVVAIYDYTKDK+DELSF EG
Sbjct: 379 PPPPPPPE-DYEEEEAAVVEYSDPYAEEDPPWAPRSYLEKVVAIYDYTKDKEDELSFQEG 437

Query: 471 AIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESIMHYTD 508
           AIIYVIKKNDDGWYEGV N VTGLFPGNYVESIMHY++
Sbjct: 438 AIIYVIKKNDDGWYEGVMNGVTGLFPGNYVESIMHYSE 475


>gi|7705981 NESH protein isoform 1 [Homo sapiens]
          Length = 366

 Score =  207 bits (526), Expect = 2e-53
 Identities = 131/298 (43%), Positives = 176/298 (59%), Gaps = 23/298 (7%)

Query: 1   MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS 60
           MAELQ L E EIP+G+ AL  ++  L RVADYCE+NY+QATDKRKALEET A+TTQ+LAS
Sbjct: 1   MAELQQLQEFEIPTGREALRGNHSALLRVADYCEDNYVQATDKRKALEETMAFTTQALAS 60

Query: 61  VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120
           VAYQ+  LA + L++LD+Q + LR++E+ ++ + Q V++H EKVARREIG L T +    
Sbjct: 61  VAYQVGNLAGHTLRMLDLQGAALRQVEARVSTLGQMVNMHMEKVARREIGTLATVQRLPP 120

Query: 121 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK 180
             K+IAP N+     Y R+P+++  LDD+GHG+K L     + Q +RTGTLSR    + K
Sbjct: 121 GQKVIAPENLPPLTPYCRRPLNFGCLDDIGHGIKDL-----STQLSRTGTLSR---KSIK 172

Query: 181 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS 240
            P+ P S   TLGR  P +  EPV  P VP+  +++ +   S  S G    +   P T  
Sbjct: 173 APATPAS--ATLGR--PPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAP-TPK 227

Query: 241 GSSGGSGSRENSGSSSIGIPIAVPT-PSPPTIGPENISVPPPS-------GAPPAPPL 290
           G +        S       P AV     PPT+  E +S PPP          PP PPL
Sbjct: 228 GQAAPPAPPLPSSLDPPPPPAAVEVFQRPPTL--EELSPPPPDEELPLPLDLPPPPPL 283



 Score =  114 bits (285), Expect = 2e-25
 Identities = 72/215 (33%), Positives = 102/215 (47%), Gaps = 34/215 (15%)

Query: 309 SQYGTMTRQISRHNSTTSSTSSGGYRRTPS-----------VTAQFSAQPHVNGGPLYSQ 357
           S+ GT++R+  +  +T +S + G   R P            ++A  SA    + G     
Sbjct: 161 SRTGTLSRKSIKAPATPASATLGRPPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGV 220

Query: 358 NSI-----SIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPP------PPPPPDDIPM 406
                     APP PP+P      P    V   Q        PP      PPPP +++P+
Sbjct: 221 GGAPTPKGQAAPPAPPLPSSLDPPPPPAAVEVFQR-------PPTLEELSPPPPDEELPL 273

Query: 407 FDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELS 466
             D PPPPP      + +E  +      +   +P+W P +Y+EKVV +Y YT  KD+ELS
Sbjct: 274 PLDLPPPPP-----LDGDELGLPPPPPGFGPDEPSWVPASYLEKVVTLYPYTSQKDNELS 328

Query: 467 FMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVE 501
           F EG +I V ++  DGW EGV +  TG FPGNYVE
Sbjct: 329 FSEGTVICVTRRYSDGWCEGVSSEGTGFFPGNYVE 363


>gi|206597502 NESH protein isoform 2 [Homo sapiens]
          Length = 360

 Score =  197 bits (502), Expect = 1e-50
 Identities = 130/298 (43%), Positives = 173/298 (58%), Gaps = 29/298 (9%)

Query: 1   MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS 60
           MAELQ L E EIP+G+ AL  ++  L RVADYCE+NY+QATDKRKALEET A+TTQ+LAS
Sbjct: 1   MAELQQLQEFEIPTGREALRGNHSALLRVADYCEDNYVQATDKRKALEETMAFTTQALAS 60

Query: 61  VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120
           VAYQ+  LA + L++LD+Q + LR++E      ++ V++H EKVARREIG L T +    
Sbjct: 61  VAYQVGNLAGHTLRMLDLQGAALRQVE------ARMVNMHMEKVARREIGTLATVQRLPP 114

Query: 121 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK 180
             K+IAP N+     Y R+P+++  LDD+GHG+K L     + Q +RTGTLSR    + K
Sbjct: 115 GQKVIAPENLPPLTPYCRRPLNFGCLDDIGHGIKDL-----STQLSRTGTLSR---KSIK 166

Query: 181 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS 240
            P+ P S   TLGR  P +  EPV  P VP+  +++ +   S  S G    +   P T  
Sbjct: 167 APATPAS--ATLGR--PPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAP-TPK 221

Query: 241 GSSGGSGSRENSGSSSIGIPIAVPT-PSPPTIGPENISVPPPS-------GAPPAPPL 290
           G +        S       P AV     PPT+  E +S PPP          PP PPL
Sbjct: 222 GQAAPPAPPLPSSLDPPPPPAAVEVFQRPPTL--EELSPPPPDEELPLPLDLPPPPPL 277



 Score =  114 bits (285), Expect = 2e-25
 Identities = 72/215 (33%), Positives = 102/215 (47%), Gaps = 34/215 (15%)

Query: 309 SQYGTMTRQISRHNSTTSSTSSGGYRRTPS-----------VTAQFSAQPHVNGGPLYSQ 357
           S+ GT++R+  +  +T +S + G   R P            ++A  SA    + G     
Sbjct: 155 SRTGTLSRKSIKAPATPASATLGRPPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGV 214

Query: 358 NSI-----SIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPP------PPPPPDDIPM 406
                     APP PP+P      P    V   Q        PP      PPPP +++P+
Sbjct: 215 GGAPTPKGQAAPPAPPLPSSLDPPPPPAAVEVFQR-------PPTLEELSPPPPDEELPL 267

Query: 407 FDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELS 466
             D PPPPP      + +E  +      +   +P+W P +Y+EKVV +Y YT  KD+ELS
Sbjct: 268 PLDLPPPPP-----LDGDELGLPPPPPGFGPDEPSWVPASYLEKVVTLYPYTSQKDNELS 322

Query: 467 FMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVE 501
           F EG +I V ++  DGW EGV +  TG FPGNYVE
Sbjct: 323 FSEGTVICVTRRYSDGWCEGVSSEGTGFFPGNYVE 357


>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
          Length = 639

 Score = 80.1 bits (196), Expect = 4e-15
 Identities = 52/154 (33%), Positives = 64/154 (41%), Gaps = 18/154 (11%)

Query: 268 PPTIGPENISVPPPSGAPPAPPLAPLLP-VSTVIAAPGSAPGSQYGTMTRQISRHNSTTS 326
           PP +G      PPPSG PP PP  PL P        P   P S     +  +    +TT+
Sbjct: 472 PPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTT 531

Query: 327 STSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQ 386
           +T+S G    P    Q +A     G P    N   +  PP   P L P            
Sbjct: 532 TTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPP------------ 579

Query: 387 ENIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVD 420
                +P PPPPPPP    M   +PPPPPPPP+D
Sbjct: 580 ----GAPPPPPPPPPGSAGMMY-APPPPPPPPMD 608



 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 66/270 (24%), Positives = 89/270 (32%), Gaps = 87/270 (32%)

Query: 140 PID-YTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPY 198
           P+D Y     VG GV  L    G   P   G +    PP    P PP S     G   P+
Sbjct: 446 PMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPS-----GPLPPW 500

Query: 199 KTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHSGSSGGSGS------RENS 252
           +  +   PP  P     S +   S   P       Q+  T + +S G+GS      ++ +
Sbjct: 501 QQQQQQPPPPPP----PSSSMASSTPLPW------QQNTTTTTTSAGTGSIPPWQQQQAA 550

Query: 253 GSSSIGIPIAVPTPSPPTIGPENISVPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYG 312
            ++S G P     P+   + P  +  P P GAPP PP  P          PGSA      
Sbjct: 551 AAASPGAPQMQGNPTMVPL-PPGVQPPLPPGAPPPPPPPP----------PGSA------ 593

Query: 313 TMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQL 372
                                                  G +Y+       PPPPP P +
Sbjct: 594 ---------------------------------------GMMYA-------PPPPPPPPM 607

Query: 373 TPQ--IPLTGFVARVQENIADSPTPPPPPP 400
            P   + + G            P PPPPPP
Sbjct: 608 DPSNFVTMMGMGVAGMPPFGMPPAPPPPPP 637



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 53/224 (23%), Positives = 73/224 (32%), Gaps = 39/224 (17%)

Query: 212 DYMTSPARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTI 271
           +Y++  A LG    P    S +    T   S+    +  N+             P PP++
Sbjct: 312 EYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANN-------------PPPPSL 358

Query: 272 GPENISVPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSG 331
                S PP   + P+               PG  P S    +      H       +  
Sbjct: 359 MSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPN 418

Query: 332 GYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPP----PPPMPQLTPQIPLTGFVARVQE 387
           G    P         P +N GP          PP    PPPM Q     P+   V R+ +
Sbjct: 419 G----PPPPWMQPPPPPMNQGP---------HPPGHHGPPPMDQYLGSTPVGSGVYRLHQ 465

Query: 388 NIADSPTPP----PPPPPDDIPMFDDSPPPP--PPPPVDYEDEE 425
                P PP    PPPPP   P     PPPP  P PP   + ++
Sbjct: 466 GKGMMPPPPMGMMPPPPP---PPSGQPPPPPSGPLPPWQQQQQQ 506


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 71/261 (27%), Positives = 97/261 (37%), Gaps = 28/261 (10%)

Query: 170  TLSRTNPPTQKPPSPPMSGRGTLGRNT----PYKTLEPVKPPTVPNDYMTSPARLGSQHS 225
            T + T PP    PSPP++   T    T    P  T     P T P+   T+P+   +  S
Sbjct: 1426 TTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPS 1485

Query: 226  PGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENISVPPPSGAP 285
            P  T +    P T    S  + +     +S+  +P    TPSPPT      + PPP+  P
Sbjct: 1486 PPTTTTTTPPPTT--TPSPPTTTPITPPASTTTLP-PTTTPSPPT---TTTTTPPPTTTP 1539

Query: 286  PAPPLAPLL-PVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFS 344
              P   P+  P ST    P + P     T T          ++T S     TPS     +
Sbjct: 1540 SPPTTTPITPPTSTTTLPPTTTPSPPPTTTT------TPPPTTTPSPPTTTTPSPPTITT 1593

Query: 345  AQPHVNGGPLYSQNSISIAPP--PPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPD 402
              P     P     + +  PP   P  P  TP  P T         +  + TP PPP   
Sbjct: 1594 TTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTS-----TTTLPPTTTPSPPPTTT 1648

Query: 403  DIPMFDDSPPPP----PPPPV 419
              P    +P PP    P PP+
Sbjct: 1649 TTPPPTTTPSPPTTTTPSPPI 1669



 Score = 62.8 bits (151), Expect = 7e-10
 Identities = 68/267 (25%), Positives = 95/267 (35%), Gaps = 28/267 (10%)

Query: 170  TLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRT 229
            T + T PP    PSPP +   T   +T   TL P   P+ P    T+P    +   P  T
Sbjct: 1527 TTTTTTPPPTTTPSPPTTTPITPPTSTT--TLPPTTTPSPPPTTTTTPPPTTTPSPPTTT 1584

Query: 230  ASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENISVPPPSGAPPAPP 289
                  P T + ++    +  +  +++   P    TPSPPT  P    + PP+     PP
Sbjct: 1585 TP---SPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTP----ITPPTSTTTLPP 1637

Query: 290  -LAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTT---SSTSSGGYRRTPSVTAQFSA 345
               P  P +T    P +   S   T T       +TT   ++T S     TPS       
Sbjct: 1638 TTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMT 1697

Query: 346  QPHVNGGP------LYSQNSISIAPPPP-----PMPQLTPQIPLTGFV----ARVQENIA 390
             P     P        + +S +   PPP     P P  TP  P T             + 
Sbjct: 1698 TPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLT 1757

Query: 391  DSPTPPPPPPPDDIPMFDDSPPPPPPP 417
             +P PP   PP   P    +P  P  P
Sbjct: 1758 TTPLPPSITPPTFSPFSTTTPTTPCVP 1784



 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 72/295 (24%), Positives = 100/295 (33%), Gaps = 49/295 (16%)

Query: 165  PARTGTLSRTNPPTQKP------PSPPMSGRG--TLGRNTPYKTLEPVKPPTVPNDYMTS 216
            P+   + + T PPT  P      PSPP +     T    TP  T  P  P T P     S
Sbjct: 1454 PSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPAS 1513

Query: 217  PARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENI 276
               L    +P    +    P   +  S  + +     +S+  +P    TPSPP   P   
Sbjct: 1514 TTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLP-PTTTPSPP---PTTT 1569

Query: 277  SVPPPSGAP-----------------PAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQIS 319
            + PPP+  P                 P P   P  P +T    P +   S     T  I+
Sbjct: 1570 TTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSP--PTTTPIT 1627

Query: 320  RHNSTT------------SSTSSGGYRRTPSVTAQFSAQPHV----NGGPLYSQNSISIA 363
               STT            ++T++     TPS     +  P +       P  + +S    
Sbjct: 1628 PPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITT 1687

Query: 364  PPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPP 418
             P PP   +T   P T   + +      S T  P PPP    M   SP   P PP
Sbjct: 1688 TPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPP--TTMTTPSPTTTPSPP 1740



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 47/172 (27%), Positives = 62/172 (36%), Gaps = 30/172 (17%)

Query: 265  TPSPPTIGPENISVPPPSGAP---------PAPPLAPLLPVSTVIAAPGSA-PGSQYGTM 314
            TPSPPT      + PPP+  P         P P   P  P+ST    P +  P     T 
Sbjct: 1421 TPSPPTT---TTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTP 1477

Query: 315  TRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPP------P 368
            +   +  +  T++T++     TPS        P  +   L    +    P PP      P
Sbjct: 1478 SPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTT----PSPPTTTTTTP 1533

Query: 369  MPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPP---PPPP 417
             P  TP  P T  +          PT  P PPP        +PPP   P PP
Sbjct: 1534 PPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTT----TTTPPPTTTPSPP 1581



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 59/254 (23%), Positives = 82/254 (32%), Gaps = 66/254 (25%)

Query: 171  LSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTA 230
            ++  +PPT  P  PP          T   TL P   P+ P    T+P    +  SP  T 
Sbjct: 1396 ITTPSPPTTTPSPPP----------TSTTTLPPTTTPSPPTTTTTTPPPTTTP-SPPITT 1444

Query: 231  SLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENISVPPPSGAPPAPPL 290
            +    P T                          TPSPP     + +  PP    P+PP 
Sbjct: 1445 TTTPPPTT--------------------------TPSPPI----STTTTPPPTTTPSPPT 1474

Query: 291  APLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTT--SSTSSGGYRRTPSVTAQFSAQPH 348
                P +T  + P +   +   T T         T  +ST++     TPS     +  P 
Sbjct: 1475 TTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTP- 1533

Query: 349  VNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFD 408
                        +  P PP    +TP    T         +  + TP PPP     P   
Sbjct: 1534 ----------PPTTTPSPPTTTPITPPTSTT--------TLPPTTTPSPPPTTTTTPPPT 1575

Query: 409  DSPPPP----PPPP 418
             +P PP    P PP
Sbjct: 1576 TTPSPPTTTTPSPP 1589



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 63/262 (24%), Positives = 97/262 (37%), Gaps = 37/262 (14%)

Query: 165  PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRNTPYKTLEPVKP---PTVPNDYMTSP 217
            P  TGT + T  P    T   P+P  +G  T    TP  T   V P   PT      T+P
Sbjct: 1934 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTP 1992

Query: 218  ARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENIS 277
                +  +P  T +  Q P T   ++  + +   + + +       PT +P T       
Sbjct: 1993 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 2047

Query: 278  VPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTP 337
             P P+G    P   P+   +TV   P +  G+Q  T T   +    T + T +G   +TP
Sbjct: 2048 TPTPTGTQ-TPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTG--TQTP 2103

Query: 338  SVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPP 396
            + T            P+    + ++ P P P    TP   P+T         +  +PTP 
Sbjct: 2104 TTT------------PI--TTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPT 2144

Query: 397  PPPPPDDIPMFDDSPPPPPPPP 418
                P   P+   +   P P P
Sbjct: 2145 GTQTPTTTPITTTTTVTPTPTP 2166



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 63/262 (24%), Positives = 97/262 (37%), Gaps = 37/262 (14%)

Query: 165  PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRNTPYKTLEPVKP---PTVPNDYMTSP 217
            P  TGT + T  P    T   P+P  +G  T    TP  T   V P   PT      T+P
Sbjct: 2003 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTP 2061

Query: 218  ARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENIS 277
                +  +P  T +  Q P T   ++  + +   + + +       PT +P T       
Sbjct: 2062 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 2116

Query: 278  VPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTP 337
             P P+G    P   P+   +TV   P +  G+Q  T T   +    T + T +G   +TP
Sbjct: 2117 TPTPTGTQ-TPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTG--TQTP 2172

Query: 338  SVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPP 396
            + T            P+    + ++ P P P    TP   P+T         +  +PTP 
Sbjct: 2173 TTT------------PI--TTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPT 2213

Query: 397  PPPPPDDIPMFDDSPPPPPPPP 418
                P   P+   +   P P P
Sbjct: 2214 GTQTPTTTPITTTTTVTPTPTP 2235



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 63/262 (24%), Positives = 97/262 (37%), Gaps = 37/262 (14%)

Query: 165  PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRNTPYKTLEPVKP---PTVPNDYMTSP 217
            P  TGT + T  P    T   P+P  +G  T    TP  T   V P   PT      T+P
Sbjct: 2072 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTP 2130

Query: 218  ARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENIS 277
                +  +P  T +  Q P T   ++  + +   + + +       PT +P T       
Sbjct: 2131 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 2185

Query: 278  VPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTP 337
             P P+G    P   P+   +TV   P +  G+Q  T T   +    T + T +G   +TP
Sbjct: 2186 TPTPTGTQ-TPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTG--TQTP 2241

Query: 338  SVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPP 396
            + T            P+    + ++ P P P    TP   P+T         +  +PTP 
Sbjct: 2242 TTT------------PI--TTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPT 2282

Query: 397  PPPPPDDIPMFDDSPPPPPPPP 418
                P   P+   +   P P P
Sbjct: 2283 GTQTPTTTPITTTTTVTPTPTP 2304



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 63/262 (24%), Positives = 97/262 (37%), Gaps = 37/262 (14%)

Query: 165  PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRNTPYKTLEPVKP---PTVPNDYMTSP 217
            P  TGT + T  P    T   P+P  +G  T    TP  T   V P   PT      T+P
Sbjct: 2141 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTP 2199

Query: 218  ARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENIS 277
                +  +P  T +  Q P T   ++  + +   + + +       PT +P T       
Sbjct: 2200 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 2254

Query: 278  VPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTP 337
             P P+G    P   P+   +TV   P +  G+Q  T T   +    T + T +G   +TP
Sbjct: 2255 TPTPTGTQ-TPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTG--TQTP 2310

Query: 338  SVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPP 396
            + T            P+    + ++ P P P    TP   P+T         +  +PTP 
Sbjct: 2311 TTT------------PI--TTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPT 2351

Query: 397  PPPPPDDIPMFDDSPPPPPPPP 418
                P   P+   +   P P P
Sbjct: 2352 GTQTPTTTPITTTTTVTPTPTP 2373



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 63/262 (24%), Positives = 97/262 (37%), Gaps = 37/262 (14%)

Query: 165  PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRNTPYKTLEPVKP---PTVPNDYMTSP 217
            P  TGT + T  P    T   P+P  +G  T    TP  T   V P   PT      T+P
Sbjct: 2210 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTP 2268

Query: 218  ARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENIS 277
                +  +P  T +  Q P T   ++  + +   + + +       PT +P T       
Sbjct: 2269 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 2323

Query: 278  VPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTP 337
             P P+G    P   P+   +TV   P +  G+Q  T T   +    T + T +G   +TP
Sbjct: 2324 TPTPTGTQ-TPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTG--TQTP 2379

Query: 338  SVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPP 396
            + T            P+    + ++ P P P    TP   P+T         +  +PTP 
Sbjct: 2380 TTT------------PI--TTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPT 2420

Query: 397  PPPPPDDIPMFDDSPPPPPPPP 418
                P   P+   +   P P P
Sbjct: 2421 GTQTPTTTPITTTTTVTPTPTP 2442



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 63/262 (24%), Positives = 97/262 (37%), Gaps = 37/262 (14%)

Query: 165  PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRNTPYKTLEPVKP---PTVPNDYMTSP 217
            P  TGT + T  P    T   P+P  +G  T    TP  T   V P   PT      T+P
Sbjct: 2279 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTP 2337

Query: 218  ARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENIS 277
                +  +P  T +  Q P T   ++  + +   + + +       PT +P T       
Sbjct: 2338 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 2392

Query: 278  VPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTP 337
             P P+G    P   P+   +TV   P +  G+Q  T T   +    T + T +G   +TP
Sbjct: 2393 TPTPTGTQ-TPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTG--TQTP 2448

Query: 338  SVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPP 396
            + T            P+    + ++ P P P    TP   P+T         +  +PTP 
Sbjct: 2449 TTT------------PI--TTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPT 2489

Query: 397  PPPPPDDIPMFDDSPPPPPPPP 418
                P   P+   +   P P P
Sbjct: 2490 GTQTPTTTPITTTTTVTPTPTP 2511



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 63/262 (24%), Positives = 97/262 (37%), Gaps = 37/262 (14%)

Query: 165  PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRNTPYKTLEPVKP---PTVPNDYMTSP 217
            P  TGT + T  P    T   P+P  +G  T    TP  T   V P   PT      T+P
Sbjct: 2348 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTP 2406

Query: 218  ARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENIS 277
                +  +P  T +  Q P T   ++  + +   + + +       PT +P T       
Sbjct: 2407 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 2461

Query: 278  VPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTP 337
             P P+G    P   P+   +TV   P +  G+Q  T T   +    T + T +G   +TP
Sbjct: 2462 TPTPTGTQ-TPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTG--TQTP 2517

Query: 338  SVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPP 396
            + T            P+    + ++ P P P    TP   P+T         +  +PTP 
Sbjct: 2518 TTT------------PI--TTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPT 2558

Query: 397  PPPPPDDIPMFDDSPPPPPPPP 418
                P   P+   +   P P P
Sbjct: 2559 GTQTPTTTPITTTTTVTPTPTP 2580



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 63/262 (24%), Positives = 97/262 (37%), Gaps = 37/262 (14%)

Query: 165  PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRNTPYKTLEPVKP---PTVPNDYMTSP 217
            P  TGT + T  P    T   P+P  +G  T    TP  T   V P   PT      T+P
Sbjct: 2417 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTP 2475

Query: 218  ARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENIS 277
                +  +P  T +  Q P T   ++  + +   + + +       PT +P T       
Sbjct: 2476 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 2530

Query: 278  VPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTP 337
             P P+G    P   P+   +TV   P +  G+Q  T T   +    T + T +G   +TP
Sbjct: 2531 TPTPTGTQ-TPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTG--TQTP 2586

Query: 338  SVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPP 396
            + T            P+    + ++ P P P    TP   P+T         +  +PTP 
Sbjct: 2587 TTT------------PI--TTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPT 2627

Query: 397  PPPPPDDIPMFDDSPPPPPPPP 418
                P   P+   +   P P P
Sbjct: 2628 GTQTPTTTPITTTTTVTPTPTP 2649



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 63/262 (24%), Positives = 97/262 (37%), Gaps = 37/262 (14%)

Query: 165  PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRNTPYKTLEPVKP---PTVPNDYMTSP 217
            P  TGT + T  P    T   P+P  +G  T    TP  T   V P   PT      T+P
Sbjct: 2486 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTP 2544

Query: 218  ARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENIS 277
                +  +P  T +  Q P T   ++  + +   + + +       PT +P T       
Sbjct: 2545 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 2599

Query: 278  VPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTP 337
             P P+G    P   P+   +TV   P +  G+Q  T T   +    T + T +G   +TP
Sbjct: 2600 TPTPTGTQ-TPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTG--TQTP 2655

Query: 338  SVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPP 396
            + T            P+    + ++ P P P    TP   P+T         +  +PTP 
Sbjct: 2656 TTT------------PI--TTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPT 2696

Query: 397  PPPPPDDIPMFDDSPPPPPPPP 418
                P   P+   +   P P P
Sbjct: 2697 GTQTPTTTPITTTTTVTPTPTP 2718



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 63/262 (24%), Positives = 97/262 (37%), Gaps = 37/262 (14%)

Query: 165  PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRNTPYKTLEPVKP---PTVPNDYMTSP 217
            P  TGT + T  P    T   P+P  +G  T    TP  T   V P   PT      T+P
Sbjct: 2555 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTP 2613

Query: 218  ARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENIS 277
                +  +P  T +  Q P T   ++  + +   + + +       PT +P T       
Sbjct: 2614 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 2668

Query: 278  VPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTP 337
             P P+G    P   P+   +TV   P +  G+Q  T T   +    T + T +G   +TP
Sbjct: 2669 TPTPTGTQ-TPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTG--TQTP 2724

Query: 338  SVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPP 396
            + T            P+    + ++ P P P    TP   P+T         +  +PTP 
Sbjct: 2725 TTT------------PI--TTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPT 2765

Query: 397  PPPPPDDIPMFDDSPPPPPPPP 418
                P   P+   +   P P P
Sbjct: 2766 GTQTPTTTPITTTTTVTPTPTP 2787



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 63/262 (24%), Positives = 97/262 (37%), Gaps = 37/262 (14%)

Query: 165  PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRNTPYKTLEPVKP---PTVPNDYMTSP 217
            P  TGT + T  P    T   P+P  +G  T    TP  T   V P   PT      T+P
Sbjct: 2624 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTP 2682

Query: 218  ARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENIS 277
                +  +P  T +  Q P T   ++  + +   + + +       PT +P T       
Sbjct: 2683 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 2737

Query: 278  VPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTP 337
             P P+G    P   P+   +TV   P +  G+Q  T T   +    T + T +G   +TP
Sbjct: 2738 TPTPTGTQ-TPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTG--TQTP 2793

Query: 338  SVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPP 396
            + T            P+    + ++ P P P    TP   P+T         +  +PTP 
Sbjct: 2794 TTT------------PI--TTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPT 2834

Query: 397  PPPPPDDIPMFDDSPPPPPPPP 418
                P   P+   +   P P P
Sbjct: 2835 GTQTPTTTPITTTTTVTPTPTP 2856



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 63/262 (24%), Positives = 97/262 (37%), Gaps = 37/262 (14%)

Query: 165  PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRNTPYKTLEPVKP---PTVPNDYMTSP 217
            P  TGT + T  P    T   P+P  +G  T    TP  T   V P   PT      T+P
Sbjct: 2693 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTP 2751

Query: 218  ARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENIS 277
                +  +P  T +  Q P T   ++  + +   + + +       PT +P T       
Sbjct: 2752 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 2806

Query: 278  VPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTP 337
             P P+G    P   P+   +TV   P +  G+Q  T T   +    T + T +G   +TP
Sbjct: 2807 TPTPTGTQ-TPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTG--TQTP 2862

Query: 338  SVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPP 396
            + T            P+    + ++ P P P    TP   P+T         +  +PTP 
Sbjct: 2863 TTT------------PI--TTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPT 2903

Query: 397  PPPPPDDIPMFDDSPPPPPPPP 418
                P   P+   +   P P P
Sbjct: 2904 GTQTPTTTPITTTTTVTPTPTP 2925



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 63/262 (24%), Positives = 97/262 (37%), Gaps = 37/262 (14%)

Query: 165  PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRNTPYKTLEPVKP---PTVPNDYMTSP 217
            P  TGT + T  P    T   P+P  +G  T    TP  T   V P   PT      T+P
Sbjct: 2762 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTP 2820

Query: 218  ARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENIS 277
                +  +P  T +  Q P T   ++  + +   + + +       PT +P T       
Sbjct: 2821 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 2875

Query: 278  VPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTP 337
             P P+G    P   P+   +TV   P +  G+Q  T T   +    T + T +G   +TP
Sbjct: 2876 TPTPTGTQ-TPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTG--TQTP 2931

Query: 338  SVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPP 396
            + T            P+    + ++ P P P    TP   P+T         +  +PTP 
Sbjct: 2932 TTT------------PI--TTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPT 2972

Query: 397  PPPPPDDIPMFDDSPPPPPPPP 418
                P   P+   +   P P P
Sbjct: 2973 GTQTPTTTPITTTTTVTPTPTP 2994



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 63/262 (24%), Positives = 97/262 (37%), Gaps = 37/262 (14%)

Query: 165  PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRNTPYKTLEPVKP---PTVPNDYMTSP 217
            P  TGT + T  P    T   P+P  +G  T    TP  T   V P   PT      T+P
Sbjct: 2831 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTP 2889

Query: 218  ARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENIS 277
                +  +P  T +  Q P T   ++  + +   + + +       PT +P T       
Sbjct: 2890 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 2944

Query: 278  VPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTP 337
             P P+G    P   P+   +TV   P +  G+Q  T T   +    T + T +G   +TP
Sbjct: 2945 TPTPTGTQ-TPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTG--TQTP 3000

Query: 338  SVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPP 396
            + T            P+    + ++ P P P    TP   P+T         +  +PTP 
Sbjct: 3001 TTT------------PI--TTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPT 3041

Query: 397  PPPPPDDIPMFDDSPPPPPPPP 418
                P   P+   +   P P P
Sbjct: 3042 GTQTPTTTPITTTTTVTPTPTP 3063



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 63/262 (24%), Positives = 97/262 (37%), Gaps = 37/262 (14%)

Query: 165  PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRNTPYKTLEPVKP---PTVPNDYMTSP 217
            P  TGT + T  P    T   P+P  +G  T    TP  T   V P   PT      T+P
Sbjct: 2900 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTP 2958

Query: 218  ARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENIS 277
                +  +P  T +  Q P T   ++  + +   + + +       PT +P T       
Sbjct: 2959 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 3013

Query: 278  VPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTP 337
             P P+G    P   P+   +TV   P +  G+Q  T T   +    T + T +G   +TP
Sbjct: 3014 TPTPTGTQ-TPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTG--TQTP 3069

Query: 338  SVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPP 396
            + T            P+    + ++ P P P    TP   P+T         +  +PTP 
Sbjct: 3070 TTT------------PI--TTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPT 3110

Query: 397  PPPPPDDIPMFDDSPPPPPPPP 418
                P   P+   +   P P P
Sbjct: 3111 GTQTPTTTPITTTTTVTPTPTP 3132



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 63/262 (24%), Positives = 97/262 (37%), Gaps = 37/262 (14%)

Query: 165  PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRNTPYKTLEPVKP---PTVPNDYMTSP 217
            P  TGT + T  P    T   P+P  +G  T    TP  T   V P   PT      T+P
Sbjct: 2969 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTP 3027

Query: 218  ARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENIS 277
                +  +P  T +  Q P T   ++  + +   + + +       PT +P T       
Sbjct: 3028 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 3082

Query: 278  VPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTP 337
             P P+G    P   P+   +TV   P +  G+Q  T T   +    T + T +G   +TP
Sbjct: 3083 TPTPTGTQ-TPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTG--TQTP 3138

Query: 338  SVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPP 396
            + T            P+    + ++ P P P    TP   P+T         +  +PTP 
Sbjct: 3139 TTT------------PI--TTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPT 3179

Query: 397  PPPPPDDIPMFDDSPPPPPPPP 418
                P   P+   +   P P P
Sbjct: 3180 GTQTPTTTPITTTTTVTPTPTP 3201



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 63/262 (24%), Positives = 97/262 (37%), Gaps = 37/262 (14%)

Query: 165  PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRNTPYKTLEPVKP---PTVPNDYMTSP 217
            P  TGT + T  P    T   P+P  +G  T    TP  T   V P   PT      T+P
Sbjct: 3038 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTP 3096

Query: 218  ARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENIS 277
                +  +P  T +  Q P T   ++  + +   + + +       PT +P T       
Sbjct: 3097 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 3151

Query: 278  VPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTP 337
             P P+G    P   P+   +TV   P +  G+Q  T T   +    T + T +G   +TP
Sbjct: 3152 TPTPTGTQ-TPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTG--TQTP 3207

Query: 338  SVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPP 396
            + T            P+    + ++ P P P    TP   P+T         +  +PTP 
Sbjct: 3208 TTT------------PI--TTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPT 3248

Query: 397  PPPPPDDIPMFDDSPPPPPPPP 418
                P   P+   +   P P P
Sbjct: 3249 GTQTPTTTPITTTTTVTPTPTP 3270



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 63/262 (24%), Positives = 97/262 (37%), Gaps = 37/262 (14%)

Query: 165  PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRNTPYKTLEPVKP---PTVPNDYMTSP 217
            P  TGT + T  P    T   P+P  +G  T    TP  T   V P   PT      T+P
Sbjct: 3107 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTP 3165

Query: 218  ARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENIS 277
                +  +P  T +  Q P T   ++  + +   + + +       PT +P T       
Sbjct: 3166 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 3220

Query: 278  VPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTP 337
             P P+G    P   P+   +TV   P +  G+Q  T T   +    T + T +G   +TP
Sbjct: 3221 TPTPTGTQ-TPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTG--TQTP 3276

Query: 338  SVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPP 396
            + T            P+    + ++ P P P    TP   P+T         +  +PTP 
Sbjct: 3277 TTT------------PI--TTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPT 3317

Query: 397  PPPPPDDIPMFDDSPPPPPPPP 418
                P   P+   +   P P P
Sbjct: 3318 GTQTPTTTPITTTTTVTPTPTP 3339



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 63/262 (24%), Positives = 97/262 (37%), Gaps = 37/262 (14%)

Query: 165  PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRNTPYKTLEPVKP---PTVPNDYMTSP 217
            P  TGT + T  P    T   P+P  +G  T    TP  T   V P   PT      T+P
Sbjct: 3176 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTP 3234

Query: 218  ARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENIS 277
                +  +P  T +  Q P T   ++  + +   + + +       PT +P T       
Sbjct: 3235 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 3289

Query: 278  VPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTP 337
             P P+G    P   P+   +TV   P +  G+Q  T T   +    T + T +G   +TP
Sbjct: 3290 TPTPTGTQ-TPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTG--TQTP 3345

Query: 338  SVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPP 396
            + T            P+    + ++ P P P    TP   P+T         +  +PTP 
Sbjct: 3346 TTT------------PI--TTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPT 3386

Query: 397  PPPPPDDIPMFDDSPPPPPPPP 418
                P   P+   +   P P P
Sbjct: 3387 GTQTPTTTPITTTTTVTPTPTP 3408



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 63/262 (24%), Positives = 97/262 (37%), Gaps = 37/262 (14%)

Query: 165  PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRNTPYKTLEPVKP---PTVPNDYMTSP 217
            P  TGT + T  P    T   P+P  +G  T    TP  T   V P   PT      T+P
Sbjct: 3245 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTP 3303

Query: 218  ARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENIS 277
                +  +P  T +  Q P T   ++  + +   + + +       PT +P T       
Sbjct: 3304 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 3358

Query: 278  VPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTP 337
             P P+G    P   P+   +TV   P +  G+Q  T T   +    T + T +G   +TP
Sbjct: 3359 TPTPTGTQ-TPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTG--TQTP 3414

Query: 338  SVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPP 396
            + T            P+    + ++ P P P    TP   P+T         +  +PTP 
Sbjct: 3415 TTT------------PI--TTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPT 3455

Query: 397  PPPPPDDIPMFDDSPPPPPPPP 418
                P   P+   +   P P P
Sbjct: 3456 GTQTPTTTPITTTTTVTPTPTP 3477



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 63/262 (24%), Positives = 97/262 (37%), Gaps = 37/262 (14%)

Query: 165  PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRNTPYKTLEPVKP---PTVPNDYMTSP 217
            P  TGT + T  P    T   P+P  +G  T    TP  T   V P   PT      T+P
Sbjct: 3314 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTP 3372

Query: 218  ARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENIS 277
                +  +P  T +  Q P T   ++  + +   + + +       PT +P T       
Sbjct: 3373 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 3427

Query: 278  VPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTP 337
             P P+G    P   P+   +TV   P +  G+Q  T T   +    T + T +G   +TP
Sbjct: 3428 TPTPTGTQ-TPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTG--TQTP 3483

Query: 338  SVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPP 396
            + T            P+    + ++ P P P    TP   P+T         +  +PTP 
Sbjct: 3484 TTT------------PI--TTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPT 3524

Query: 397  PPPPPDDIPMFDDSPPPPPPPP 418
                P   P+   +   P P P
Sbjct: 3525 GTQTPTTTPITTTTTVTPTPTP 3546



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 63/262 (24%), Positives = 97/262 (37%), Gaps = 37/262 (14%)

Query: 165  PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRNTPYKTLEPVKP---PTVPNDYMTSP 217
            P  TGT + T  P    T   P+P  +G  T    TP  T   V P   PT      T+P
Sbjct: 3383 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTP 3441

Query: 218  ARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENIS 277
                +  +P  T +  Q P T   ++  + +   + + +       PT +P T       
Sbjct: 3442 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 3496

Query: 278  VPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTP 337
             P P+G    P   P+   +TV   P +  G+Q  T T   +    T + T +G   +TP
Sbjct: 3497 TPTPTGTQ-TPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTG--TQTP 3552

Query: 338  SVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPP 396
            + T            P+    + ++ P P P    TP   P+T         +  +PTP 
Sbjct: 3553 TTT------------PI--TTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPT 3593

Query: 397  PPPPPDDIPMFDDSPPPPPPPP 418
                P   P+   +   P P P
Sbjct: 3594 GTQTPTTTPITTTTTVTPTPTP 3615



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 63/262 (24%), Positives = 97/262 (37%), Gaps = 37/262 (14%)

Query: 165  PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRNTPYKTLEPVKP---PTVPNDYMTSP 217
            P  TGT + T  P    T   P+P  +G  T    TP  T   V P   PT      T+P
Sbjct: 3452 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTP 3510

Query: 218  ARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENIS 277
                +  +P  T +  Q P T   ++  + +   + + +       PT +P T       
Sbjct: 3511 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 3565

Query: 278  VPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTP 337
             P P+G    P   P+   +TV   P +  G+Q  T T   +    T + T +G   +TP
Sbjct: 3566 TPTPTGTQ-TPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTG--TQTP 3621

Query: 338  SVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPP 396
            + T            P+    + ++ P P P    TP   P+T         +  +PTP 
Sbjct: 3622 TTT------------PI--TTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPT 3662

Query: 397  PPPPPDDIPMFDDSPPPPPPPP 418
                P   P+   +   P P P
Sbjct: 3663 GTQTPTTTPITTTTTVTPTPTP 3684



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 63/262 (24%), Positives = 97/262 (37%), Gaps = 37/262 (14%)

Query: 165  PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRNTPYKTLEPVKP---PTVPNDYMTSP 217
            P  TGT + T  P    T   P+P  +G  T    TP  T   V P   PT      T+P
Sbjct: 3521 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTP 3579

Query: 218  ARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENIS 277
                +  +P  T +  Q P T   ++  + +   + + +       PT +P T       
Sbjct: 3580 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 3634

Query: 278  VPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTP 337
             P P+G    P   P+   +TV   P +  G+Q  T T   +    T + T +G   +TP
Sbjct: 3635 TPTPTGTQ-TPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTG--TQTP 3690

Query: 338  SVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPP 396
            + T            P+    + ++ P P P    TP   P+T         +  +PTP 
Sbjct: 3691 TTT------------PI--TTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPT 3731

Query: 397  PPPPPDDIPMFDDSPPPPPPPP 418
                P   P+   +   P P P
Sbjct: 3732 GTQTPTTTPITTTTTVTPTPTP 3753



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 63/262 (24%), Positives = 97/262 (37%), Gaps = 37/262 (14%)

Query: 165  PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRNTPYKTLEPVKP---PTVPNDYMTSP 217
            P  TGT + T  P    T   P+P  +G  T    TP  T   V P   PT      T+P
Sbjct: 3590 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTP 3648

Query: 218  ARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENIS 277
                +  +P  T +  Q P T   ++  + +   + + +       PT +P T       
Sbjct: 3649 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 3703

Query: 278  VPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTP 337
             P P+G    P   P+   +TV   P +  G+Q  T T   +    T + T +G   +TP
Sbjct: 3704 TPTPTGTQ-TPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTG--TQTP 3759

Query: 338  SVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPP 396
            + T            P+    + ++ P P P    TP   P+T         +  +PTP 
Sbjct: 3760 TTT------------PI--TTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPT 3800

Query: 397  PPPPPDDIPMFDDSPPPPPPPP 418
                P   P+   +   P P P
Sbjct: 3801 GTQTPTTTPITTTTTVTPTPTP 3822



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 63/262 (24%), Positives = 97/262 (37%), Gaps = 37/262 (14%)

Query: 165  PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRNTPYKTLEPVKP---PTVPNDYMTSP 217
            P  TGT + T  P    T   P+P  +G  T    TP  T   V P   PT      T+P
Sbjct: 3659 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTP 3717

Query: 218  ARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENIS 277
                +  +P  T +  Q P T   ++  + +   + + +       PT +P T       
Sbjct: 3718 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 3772

Query: 278  VPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTP 337
             P P+G    P   P+   +TV   P +  G+Q  T T   +    T + T +G   +TP
Sbjct: 3773 TPTPTGTQ-TPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTG--TQTP 3828

Query: 338  SVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPP 396
            + T            P+    + ++ P P P    TP   P+T         +  +PTP 
Sbjct: 3829 TTT------------PI--TTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPT 3869

Query: 397  PPPPPDDIPMFDDSPPPPPPPP 418
                P   P+   +   P P P
Sbjct: 3870 GTQTPTTTPITTTTTVTPTPTP 3891



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 63/262 (24%), Positives = 97/262 (37%), Gaps = 37/262 (14%)

Query: 165  PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRNTPYKTLEPVKP---PTVPNDYMTSP 217
            P  TGT + T  P    T   P+P  +G  T    TP  T   V P   PT      T+P
Sbjct: 3728 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTP 3786

Query: 218  ARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENIS 277
                +  +P  T +  Q P T   ++  + +   + + +       PT +P T       
Sbjct: 3787 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 3841

Query: 278  VPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTP 337
             P P+G    P   P+   +TV   P +  G+Q  T T   +    T + T +G   +TP
Sbjct: 3842 TPTPTGTQ-TPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTG--TQTP 3897

Query: 338  SVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPP 396
            + T            P+    + ++ P P P    TP   P+T         +  +PTP 
Sbjct: 3898 TTT------------PI--TTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPT 3938

Query: 397  PPPPPDDIPMFDDSPPPPPPPP 418
                P   P+   +   P P P
Sbjct: 3939 GTQTPTTTPITTTTTVTPTPTP 3960



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 63/262 (24%), Positives = 97/262 (37%), Gaps = 37/262 (14%)

Query: 165  PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRNTPYKTLEPVKP---PTVPNDYMTSP 217
            P  TGT + T  P    T   P+P  +G  T    TP  T   V P   PT      T+P
Sbjct: 3797 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTP 3855

Query: 218  ARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENIS 277
                +  +P  T +  Q P T   ++  + +   + + +       PT +P T       
Sbjct: 3856 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 3910

Query: 278  VPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTP 337
             P P+G    P   P+   +TV   P +  G+Q  T T   +    T + T +G   +TP
Sbjct: 3911 TPTPTGTQ-TPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTG--TQTP 3966

Query: 338  SVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPP 396
            + T            P+    + ++ P P P    TP   P+T         +  +PTP 
Sbjct: 3967 TTT------------PI--TTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPT 4007

Query: 397  PPPPPDDIPMFDDSPPPPPPPP 418
                P   P+   +   P P P
Sbjct: 4008 GTQTPTTTPITTTTTVTPTPTP 4029



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 63/262 (24%), Positives = 97/262 (37%), Gaps = 37/262 (14%)

Query: 165  PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRNTPYKTLEPVKP---PTVPNDYMTSP 217
            P  TGT + T  P    T   P+P  +G  T    TP  T   V P   PT      T+P
Sbjct: 3866 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTP 3924

Query: 218  ARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENIS 277
                +  +P  T +  Q P T   ++  + +   + + +       PT +P T       
Sbjct: 3925 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 3979

Query: 278  VPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTP 337
             P P+G    P   P+   +TV   P +  G+Q  T T   +    T + T +G   +TP
Sbjct: 3980 TPTPTGTQ-TPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTG--TQTP 4035

Query: 338  SVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPP 396
            + T            P+    + ++ P P P    TP   P+T         +  +PTP 
Sbjct: 4036 TTT------------PI--TTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPT 4076

Query: 397  PPPPPDDIPMFDDSPPPPPPPP 418
                P   P+   +   P P P
Sbjct: 4077 GTQTPTTTPITTTTTVTPTPTP 4098



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 63/262 (24%), Positives = 98/262 (37%), Gaps = 37/262 (14%)

Query: 165  PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRNTPYKTLEPVKP---PTVPNDYMTSP 217
            P  TGT + T  P    T   P+P  +G  T    TP  T   V P   PT      T+P
Sbjct: 3889 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTP 3947

Query: 218  ARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENIS 277
                +  +P  T +  Q P T   ++  + +   + + +       PT +P T       
Sbjct: 3948 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 4002

Query: 278  VPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTP 337
             P P+G    P   P+   +TV   P +  G+Q  T T   +    T + T +G   +TP
Sbjct: 4003 TPTPTGTQ-TPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTG--TQTP 4058

Query: 338  SVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQI-PLTGFVARVQENIADSPTPP 396
            + T            P+ +  +++  P P P    TP   P+T         +  +PTP 
Sbjct: 4059 TTT------------PITTTTTVT--PTPTPTGTQTPTTTPIT-----TTTTVTPTPTPT 4099

Query: 397  PPPPPDDIPMFDDSPPPPPPPP 418
                P   P+   +   P P P
Sbjct: 4100 GTQTPTTTPITTTTTVTPTPTP 4121



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 63/262 (24%), Positives = 98/262 (37%), Gaps = 37/262 (14%)

Query: 165  PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRNTPYKTLEPVKP---PTVPNDYMTSP 217
            P  TGT + T  P    T   P+P  +G  T    TP  T   V P   PT      T+P
Sbjct: 3912 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTP 3970

Query: 218  ARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENIS 277
                +  +P  T +  Q P T   ++  + +   + + +       PT +P T       
Sbjct: 3971 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 4025

Query: 278  VPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTP 337
             P P+G    P   P+   +TV   P +  G+Q  T T   +    T + T +G   +TP
Sbjct: 4026 TPTPTGTQ-TPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTG--TQTP 4081

Query: 338  SVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQI-PLTGFVARVQENIADSPTPP 396
            + T            P+ +  +++  P P P    TP   P+T         +  +PTP 
Sbjct: 4082 TTT------------PITTTTTVT--PTPTPTGTQTPTTTPIT-----TTTTVTPTPTPT 4122

Query: 397  PPPPPDDIPMFDDSPPPPPPPP 418
                P   P+   +   P P P
Sbjct: 4123 GTQTPTTTPITTTTTVTPTPTP 4144



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 63/262 (24%), Positives = 98/262 (37%), Gaps = 37/262 (14%)

Query: 165  PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRNTPYKTLEPVKP---PTVPNDYMTSP 217
            P  TGT + T  P    T   P+P  +G  T    TP  T   V P   PT      T+P
Sbjct: 3935 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTP 3993

Query: 218  ARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENIS 277
                +  +P  T +  Q P T   ++  + +   + + +       PT +P T       
Sbjct: 3994 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 4048

Query: 278  VPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTP 337
             P P+G    P   P+   +TV   P +  G+Q  T T   +    T + T +G   +TP
Sbjct: 4049 TPTPTGTQ-TPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTG--TQTP 4104

Query: 338  SVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQI-PLTGFVARVQENIADSPTPP 396
            + T            P+ +  +++  P P P    TP   P+T         +  +PTP 
Sbjct: 4105 TTT------------PITTTTTVT--PTPTPTGTQTPTTTPIT-----TTTTVTPTPTPT 4145

Query: 397  PPPPPDDIPMFDDSPPPPPPPP 418
                P   P+   +   P P P
Sbjct: 4146 GTQTPTTTPITTTTTVTPTPTP 4167



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 63/262 (24%), Positives = 98/262 (37%), Gaps = 37/262 (14%)

Query: 165  PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRNTPYKTLEPVKP---PTVPNDYMTSP 217
            P  TGT + T  P    T   P+P  +G  T    TP  T   V P   PT      T+P
Sbjct: 3958 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTP 4016

Query: 218  ARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENIS 277
                +  +P  T +  Q P T   ++  + +   + + +       PT +P T       
Sbjct: 4017 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 4071

Query: 278  VPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTP 337
             P P+G    P   P+   +TV   P +  G+Q  T T   +    T + T +G   +TP
Sbjct: 4072 TPTPTGTQ-TPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTG--TQTP 4127

Query: 338  SVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQI-PLTGFVARVQENIADSPTPP 396
            + T            P+ +  +++  P P P    TP   P+T         +  +PTP 
Sbjct: 4128 TTT------------PITTTTTVT--PTPTPTGTQTPTTTPIT-----TTTTVTPTPTPT 4168

Query: 397  PPPPPDDIPMFDDSPPPPPPPP 418
                P   P+   +   P P P
Sbjct: 4169 GTQTPTTTPITTTTTVTPTPTP 4190



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 59/262 (22%), Positives = 93/262 (35%), Gaps = 39/262 (14%)

Query: 168  TGTLSRTNPPTQKP----------PSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSP 217
            T T     PPT  P          P+P  +   T    T   T+ P   PT      T+P
Sbjct: 1887 TTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 1946

Query: 218  ARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENIS 277
                +  +P  T +  Q P T   ++  + +   + + +       PT +P T       
Sbjct: 1947 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 2001

Query: 278  VPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTP 337
             P P+G    P   P+   +TV   P +  G+Q  T T   +    T + T +G   +TP
Sbjct: 2002 TPTPTGT-QTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTG--TQTP 2057

Query: 338  SVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTP-QIPLTGFVARVQENIADSPTPP 396
            + T            P+    + ++ P P P    TP   P+T         +  +PTP 
Sbjct: 2058 TTT------------PI--TTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPT 2098

Query: 397  PPPPPDDIPMFDDSPPPPPPPP 418
                P   P+   +   P P P
Sbjct: 2099 GTQTPTTTPITTTTTVTPTPTP 2120



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 56/225 (24%), Positives = 80/225 (35%), Gaps = 20/225 (8%)

Query: 165  PARTGT-----LSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPAR 219
            P  T T     L+ +NPP +   S P + R T    T   TL    PP +    MTS A 
Sbjct: 4198 PTHTSTAPIAELTTSNPPPES--STPQTSRSTSSPLTESTTLLSTLPPAIE---MTSTAP 4252

Query: 220  LGSQHSPGRTA---SLNQRPRTHSGSSGGSGSRENSGSSSIGIP--IAVPTPSPPTIGPE 274
              +  +P  T+   +L+  P T +   G       +GSSS   P  +   T S  T  P 
Sbjct: 4253 PSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPT 4312

Query: 275  NISVPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQ-----YGTMTRQISRHNSTTSSTS 329
             +S P         P    + +  V+     APG +     YG     ++   S T    
Sbjct: 4313 PLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFY 4372

Query: 330  SGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTP 374
            +     TPS T   S        P  + +  +    PP  P   P
Sbjct: 4373 NWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDP 4417



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 61/273 (22%), Positives = 98/273 (35%), Gaps = 25/273 (9%)

Query: 165  PARTGTLSRTNPP----TQKPPSPPMSGRGTLGRNTPYKTLEPVKP---PTVPNDYMTSP 217
            P  TGT + T  P    T   P+P  +G  T    TP  T   V P   PT      T+P
Sbjct: 4004 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTP 4062

Query: 218  ARLGSQHSPGRTASLNQRPRTH--------SGSSGGSGSRENSGSSSIGIPIAVPTPSPP 269
                +  +P  T +  Q P T         + +   +G++  + +         PTP+P 
Sbjct: 4063 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP- 4121

Query: 270  TIGPENISVPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTS 329
              G +  +  P +      P        T    P +   +   T T   ++  +TT  T+
Sbjct: 4122 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 4180

Query: 330  SGGYRRTPSVTAQFSAQP-HVNGGPLYSQNSISIAPPPPPMPQL-----TPQIPLTGFVA 383
            +     TP+ T   +  P H +  P+ ++ + S  PP    PQ      +P    T  ++
Sbjct: 4181 TTTVTPTPTPTGTQTGPPTHTSTAPI-AELTTSNPPPESSTPQTSRSTSSPLTESTTLLS 4239

Query: 384  RVQENIADSPTPPPPPPPDDIPMFDDSPPPPPP 416
             +   I  + T PP  P             PPP
Sbjct: 4240 TLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPP 4272


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 69.3 bits (168), Expect = 8e-12
 Identities = 80/282 (28%), Positives = 100/282 (35%), Gaps = 50/282 (17%)

Query: 165 PARTGTLSRTNPPT-QKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDY-MTSPARLGS 222
           P    T +R N     +PP  P  GR T        + +P  PP+ P  + + SP     
Sbjct: 109 PKLRSTANRDNDSGGSRPPLLPPGGRST--------SAKPFSPPSGPGRFPVPSPGHRSG 160

Query: 223 QHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVP-TPSPPTIGPENISVPPP 281
              P R      RP              + GS    IP  VP TP P    P N   PP 
Sbjct: 161 PPEPQRNRMPPPRP--------------DVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPV 206

Query: 282 SGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRT--PSV 339
            G P  P   P          P   PG++ GT     S   S  SS+S    R    P+ 
Sbjct: 207 PGGPRQPSPGP---------TPPPFPGNR-GTALGGGSIRQSPLSSSSPFSNRPPLPPTP 256

Query: 340 TAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLT-PQIPLTGFVARVQENIADSPTPPPP 398
           +     +P     P+ ++ SI     PPP PQ   P +P T          A S  PPPP
Sbjct: 257 SRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPST------PRPSASSQAPPPP 310

Query: 399 PPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDP 440
           PPP          PPP PP     DE   + Q N   +   P
Sbjct: 311 PPPSR------PGPPPLPPSSSGNDETPRLPQRNLSLSSSTP 346



 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 78/280 (27%), Positives = 97/280 (34%), Gaps = 69/280 (24%)

Query: 160 HGNNQPARTGTLSRTNPPTQKPPSPPMSGRGTLG---RNTPYKTLEPV--KPPTVPNDYM 214
           H    P   G   + +P    PP P   G    G   R +P  +  P   +PP  P    
Sbjct: 199 HNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPP---- 254

Query: 215 TSPARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPE 274
            +P+R      P     +  RP  H         RE           AVP P P    P 
Sbjct: 255 -TPSRALDDKPPPPPPPVGNRPSIH---------RE-----------AVPPPPPQNNKPP 293

Query: 275 NISVPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTS----- 329
             S P PS +  APP  P  P S     P   P S     T ++ + N + SS++     
Sbjct: 294 VPSTPRPSASSQAPPPPP--PPSRP-GPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPS 350

Query: 330 ---SGGYRRTPSVTAQFSAQ-PHVNGGPLYSQNSISIAPPPPPMPQ---------LTPQI 376
              SG     PS       + P    GPL         PPPPP+ +          TPQ+
Sbjct: 351 PGRSGPLPPPPSERPPPPVRDPPGRSGPL---------PPPPPVSRNGSTSRALPATPQL 401

Query: 377 PLTGFVARVQENIADSPTPPPPPP-PDDIPMFDDSPPPPP 415
           P    V        DSP   P PP P D P     PPPPP
Sbjct: 402 PSRSGV--------DSPRSGPRPPLPPDRPSAGAPPPPPP 433



 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 75/275 (27%), Positives = 95/275 (34%), Gaps = 53/275 (19%)

Query: 165 PARTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPP--TVPNDYMTSPARLGS 222
           P+  G     +P  +  P  P   R    R       + + PP  + P    +SP   GS
Sbjct: 144 PSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGS 203

Query: 223 QHSPG--RTASLNQRPRTHSGSSG---GSGSRENSGSSSIGIPIAVPTPSPPT----IGP 273
              PG  R  S    P    G+ G   G GS   S  SS   P +   P PPT    +  
Sbjct: 204 PPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSS-PFSNRPPLPPTPSRALDD 262

Query: 274 ENISVPPPSGAPPA------PPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSS 327
           +    PPP G  P+      PP  P      V + P  +  SQ        SR       
Sbjct: 263 KPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLP 322

Query: 328 TSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQE 387
            SS G   TP +                 Q ++S++   PP+P      PL         
Sbjct: 323 PSSSGNDETPRLP----------------QRNLSLSSSTPPLPSPGRSGPL--------- 357

Query: 388 NIADSPTPP---PPPPPDDIPMFDDSPPPPPPPPV 419
                P PP   PPPP  D P    S P PPPPPV
Sbjct: 358 -----PPPPSERPPPPVRDPP--GRSGPLPPPPPV 385



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 64/270 (23%), Positives = 84/270 (31%), Gaps = 31/270 (11%)

Query: 176 PPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQR 235
           PP   PP PP        + T  KT +  +   + +  ++   +L    +  R+A +  +
Sbjct: 4   PPPPAPPPPPTFALANTEKPTLNKTEQAGRNALLSD--ISKGKKLKKTVTNDRSAPILDK 61

Query: 236 PRT---------------HSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENISVPP 280
           P+                  G  GG G     G    G+        P      N     
Sbjct: 62  PKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDS 121

Query: 281 PSGAPPAPP-------LAPLLPVSTVIAAPGSAPGSQYGTMTRQISRH---NSTTSSTSS 330
               PP  P         P  P S     P  +PG + G    Q +R         S   
Sbjct: 122 GGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPD 181

Query: 331 GGYRRTPSVTAQFSAQPHVNGGPLY--SQNSISIAPPPPPMPQLTPQIPLTGFVARVQEN 388
                 PS      + PH  G P         S  P PPP P       L G   R    
Sbjct: 182 SIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPG-NRGTALGGGSIRQSPL 240

Query: 389 IADSP-TPPPPPPPDDIPMFDDSPPPPPPP 417
            + SP +  PP PP      DD PPPPPPP
Sbjct: 241 SSSSPFSNRPPLPPTPSRALDDKPPPPPPP 270



 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 70/266 (26%), Positives = 89/266 (33%), Gaps = 36/266 (13%)

Query: 162 NNQPARTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPAR-- 219
           +N+P    T SR       PP PP+  R ++ R       E V PP   N+    P+   
Sbjct: 247 SNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHR-------EAVPPPPPQNNKPPVPSTPR 299

Query: 220 --LGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPT-PSPPTIGPENI 276
               SQ  P         P     SS G+         ++ +  + P  PSP   GP   
Sbjct: 300 PSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGP--- 356

Query: 277 SVPPPSGAPPAP---------PLAPLLPVST------VIAAPGSAPGSQYGTMTRQISRH 321
             PPPS  PP P         PL P  PVS        + A    P        R   R 
Sbjct: 357 LPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRP 416

Query: 322 NSTTSSTSSGGYRRTP---SVTAQFSAQP-HVNGGPLYSQNSISIAPPPPPMPQLTPQIP 377
                  S+G     P   S+   F   P        +  + IS  PPP P  Q T   P
Sbjct: 417 PLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYP 476

Query: 378 --LTGFVARVQENIADSPTPPPPPPP 401
             L    +R   N  +   PP PP P
Sbjct: 477 SKLARNESRSGSNRRERGAPPLPPIP 502


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 69.3 bits (168), Expect = 8e-12
 Identities = 80/282 (28%), Positives = 100/282 (35%), Gaps = 50/282 (17%)

Query: 165 PARTGTLSRTNPPT-QKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDY-MTSPARLGS 222
           P    T +R N     +PP  P  GR T        + +P  PP+ P  + + SP     
Sbjct: 109 PKLRSTANRDNDSGGSRPPLLPPGGRST--------SAKPFSPPSGPGRFPVPSPGHRSG 160

Query: 223 QHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVP-TPSPPTIGPENISVPPP 281
              P R      RP              + GS    IP  VP TP P    P N   PP 
Sbjct: 161 PPEPQRNRMPPPRP--------------DVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPV 206

Query: 282 SGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRT--PSV 339
            G P  P   P          P   PG++ GT     S   S  SS+S    R    P+ 
Sbjct: 207 PGGPRQPSPGP---------TPPPFPGNR-GTALGGGSIRQSPLSSSSPFSNRPPLPPTP 256

Query: 340 TAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLT-PQIPLTGFVARVQENIADSPTPPPP 398
           +     +P     P+ ++ SI     PPP PQ   P +P T          A S  PPPP
Sbjct: 257 SRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPST------PRPSASSQAPPPP 310

Query: 399 PPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDP 440
           PPP          PPP PP     DE   + Q N   +   P
Sbjct: 311 PPPSR------PGPPPLPPSSSGNDETPRLPQRNLSLSSSTP 346



 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 78/280 (27%), Positives = 97/280 (34%), Gaps = 69/280 (24%)

Query: 160 HGNNQPARTGTLSRTNPPTQKPPSPPMSGRGTLG---RNTPYKTLEPV--KPPTVPNDYM 214
           H    P   G   + +P    PP P   G    G   R +P  +  P   +PP  P    
Sbjct: 199 HNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPP---- 254

Query: 215 TSPARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPE 274
            +P+R      P     +  RP  H         RE           AVP P P    P 
Sbjct: 255 -TPSRALDDKPPPPPPPVGNRPSIH---------RE-----------AVPPPPPQNNKPP 293

Query: 275 NISVPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTS----- 329
             S P PS +  APP  P  P S     P   P S     T ++ + N + SS++     
Sbjct: 294 VPSTPRPSASSQAPPPPP--PPSRP-GPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPS 350

Query: 330 ---SGGYRRTPSVTAQFSAQ-PHVNGGPLYSQNSISIAPPPPPMPQ---------LTPQI 376
              SG     PS       + P    GPL         PPPPP+ +          TPQ+
Sbjct: 351 PGRSGPLPPPPSERPPPPVRDPPGRSGPL---------PPPPPVSRNGSTSRALPATPQL 401

Query: 377 PLTGFVARVQENIADSPTPPPPPP-PDDIPMFDDSPPPPP 415
           P    V        DSP   P PP P D P     PPPPP
Sbjct: 402 PSRSGV--------DSPRSGPRPPLPPDRPSAGAPPPPPP 433



 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 75/275 (27%), Positives = 95/275 (34%), Gaps = 53/275 (19%)

Query: 165 PARTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPP--TVPNDYMTSPARLGS 222
           P+  G     +P  +  P  P   R    R       + + PP  + P    +SP   GS
Sbjct: 144 PSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGS 203

Query: 223 QHSPG--RTASLNQRPRTHSGSSG---GSGSRENSGSSSIGIPIAVPTPSPPT----IGP 273
              PG  R  S    P    G+ G   G GS   S  SS   P +   P PPT    +  
Sbjct: 204 PPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSS-PFSNRPPLPPTPSRALDD 262

Query: 274 ENISVPPPSGAPPA------PPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSS 327
           +    PPP G  P+      PP  P      V + P  +  SQ        SR       
Sbjct: 263 KPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLP 322

Query: 328 TSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQE 387
            SS G   TP +                 Q ++S++   PP+P      PL         
Sbjct: 323 PSSSGNDETPRLP----------------QRNLSLSSSTPPLPSPGRSGPL--------- 357

Query: 388 NIADSPTPP---PPPPPDDIPMFDDSPPPPPPPPV 419
                P PP   PPPP  D P    S P PPPPPV
Sbjct: 358 -----PPPPSERPPPPVRDPP--GRSGPLPPPPPV 385



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 64/270 (23%), Positives = 84/270 (31%), Gaps = 31/270 (11%)

Query: 176 PPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQR 235
           PP   PP PP        + T  KT +  +   + +  ++   +L    +  R+A +  +
Sbjct: 4   PPPPAPPPPPTFALANTEKPTLNKTEQAGRNALLSD--ISKGKKLKKTVTNDRSAPILDK 61

Query: 236 PRT---------------HSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENISVPP 280
           P+                  G  GG G     G    G+        P      N     
Sbjct: 62  PKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDS 121

Query: 281 PSGAPPAPP-------LAPLLPVSTVIAAPGSAPGSQYGTMTRQISRH---NSTTSSTSS 330
               PP  P         P  P S     P  +PG + G    Q +R         S   
Sbjct: 122 GGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPD 181

Query: 331 GGYRRTPSVTAQFSAQPHVNGGPLY--SQNSISIAPPPPPMPQLTPQIPLTGFVARVQEN 388
                 PS      + PH  G P         S  P PPP P       L G   R    
Sbjct: 182 SIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPG-NRGTALGGGSIRQSPL 240

Query: 389 IADSP-TPPPPPPPDDIPMFDDSPPPPPPP 417
            + SP +  PP PP      DD PPPPPPP
Sbjct: 241 SSSSPFSNRPPLPPTPSRALDDKPPPPPPP 270



 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 70/266 (26%), Positives = 89/266 (33%), Gaps = 36/266 (13%)

Query: 162 NNQPARTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPAR-- 219
           +N+P    T SR       PP PP+  R ++ R       E V PP   N+    P+   
Sbjct: 247 SNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHR-------EAVPPPPPQNNKPPVPSTPR 299

Query: 220 --LGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPT-PSPPTIGPENI 276
               SQ  P         P     SS G+         ++ +  + P  PSP   GP   
Sbjct: 300 PSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGP--- 356

Query: 277 SVPPPSGAPPAP---------PLAPLLPVST------VIAAPGSAPGSQYGTMTRQISRH 321
             PPPS  PP P         PL P  PVS        + A    P        R   R 
Sbjct: 357 LPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRP 416

Query: 322 NSTTSSTSSGGYRRTP---SVTAQFSAQP-HVNGGPLYSQNSISIAPPPPPMPQLTPQIP 377
                  S+G     P   S+   F   P        +  + IS  PPP P  Q T   P
Sbjct: 417 PLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYP 476

Query: 378 --LTGFVARVQENIADSPTPPPPPPP 401
             L    +R   N  +   PP PP P
Sbjct: 477 SKLARNESRSGSNRRERGAPPLPPIP 502


>gi|224586851 sorbin and SH3 domain containing 2 isoform 6 [Homo
           sapiens]
          Length = 824

 Score = 66.2 bits (160), Expect = 7e-11
 Identities = 83/356 (23%), Positives = 128/356 (35%), Gaps = 47/356 (13%)

Query: 156 LKAKHGNNQP-ARTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYM 214
           L   H +N P A     S   PP   PP PP+  R     +T     +P         + 
Sbjct: 328 LSKSHSDNSPNAFKDASSPVPPPHVPPPVPPLRPRDR--SSTEKHDWDPPDRKVDTRKFR 385

Query: 215 TSPARLGSQHSPGRTASLNQR-----PRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPP 269
           + P  +  ++ PG+++ L        P T +      G R+   SS +G     P+P PP
Sbjct: 386 SEPRSI-FEYEPGKSSILQHERPPPLPTTPTPVPREPG-RKPLSSSRLGEVTGSPSP-PP 442

Query: 270 TIGPENISVPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTS 329
             G    S   P+ +P  PP  PL  V    +   +       ++ R + R  S+ S  S
Sbjct: 443 RSGAPTPSSRAPALSPTRPPKKPLDYVQDHSSGVFNEASLYQSSIDRSLERPMSSASMAS 502

Query: 330 SGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQENI 389
               RR         ++P V         S S   P         ++ L G    + ++ 
Sbjct: 503 DFRKRR--------KSEPAVGPPRGLGDQSASRTSPG--------RVDLPGSSTTLTKS- 545

Query: 390 ADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDP--YADGDPAWAPKNY 447
                            F  S P  P    D E   +      D    A  +    P+  
Sbjct: 546 -----------------FTSSSPSSPSRAKDRESPRSYSSTLTDMGRSAPRERRGTPEKE 588

Query: 448 IEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESI 503
                A+YD+      ELSF +G  +Y+++K D  WYEG  +   G+FP +YVE +
Sbjct: 589 KLPAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKL 644



 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 34/96 (35%), Positives = 47/96 (48%), Gaps = 8/96 (8%)

Query: 413 PPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNYI---EKVVAIYDYTKDKDDELSFME 469
           P PP P  Y  +    +  N P     P +  +N     E   A+Y+YT   +DEL   E
Sbjct: 732 PDPPIPHSYSSDRIHSLSSNKPQR---PVFTHENIQGGGEPFQALYNYTPRNEDELELRE 788

Query: 470 GAIIYVIKKNDDGWYEGVCNRVT--GLFPGNYVESI 503
             +I V++K DDGW+ G   R    G FPGNYV+ +
Sbjct: 789 SDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 824



 Score = 56.2 bits (134), Expect = 7e-08
 Identities = 83/350 (23%), Positives = 119/350 (34%), Gaps = 67/350 (19%)

Query: 172 SRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPG--RT 229
           SR    T  P  PP SG  T     P   L P +PP  P DY+         HS G    
Sbjct: 429 SRLGEVTGSPSPPPRSGAPTPSSRAP--ALSPTRPPKKPLDYV-------QDHSSGVFNE 479

Query: 230 ASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENISVPPPSGAPPAPP 289
           ASL Q       SS          S+S+         S P +GP    +   S +  +P 
Sbjct: 480 ASLYQ-------SSIDRSLERPMSSASMASDFRKRRKSEPAVGPPR-GLGDQSASRTSPG 531

Query: 290 LAPLLPVSTVIAAP--GSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQP 347
              L   ST +      S+P S      R+  R  S+T +       R    T +    P
Sbjct: 532 RVDLPGSSTTLTKSFTSSSPSSPSRAKDRESPRSYSSTLTDMGRSAPRERRGTPEKEKLP 591

Query: 348 HVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSP-------TPPPPPP 400
                   +Q S  ++        +  +I    +       +   P       TPP    
Sbjct: 592 AKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKLTPPEKAQ 651

Query: 401 PDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKD 460
           P        + PPPP  P +                           I + +A Y++  D
Sbjct: 652 P--------ARPPPPAQPGE---------------------------IGEAIAKYNFNAD 676

Query: 461 KDDELSFMEGAIIYVIKKNDDGWYEGV---CNRVTGLFPGNYVESIMHYT 507
            + ELS  +G  + ++K+ D  WYEG     NR  G+FP +YVE +   T
Sbjct: 677 TNVELSLRKGDRVILLKRVDQNWYEGKIPGTNR-QGIFPVSYVEVVKKNT 725



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 58/239 (24%), Positives = 85/239 (35%), Gaps = 46/239 (19%)

Query: 196 TPYKTLEPVKPPTVPNDYMTSPARLGSQ-HSPGRTASLNQRPRTHSGSSGGSGSRENSGS 254
           T +K +  V  P    D   +P    +  ++P  +A  +   +T +        R  S S
Sbjct: 279 TMFKQIHMVHKPDDDTDMYNTPYTYNAGLYNPPYSAQSHPAAKTQT-------YRPLSKS 331

Query: 255 SSIGIPIAVPTPSPPTIGPENISVPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTM 314
            S   P A    S P        VPPP   PP PPL P    ST            +   
Sbjct: 332 HSDNSPNAFKDASSP--------VPPPHVPPPVPPLRPRDRSST--------EKHDWDPP 375

Query: 315 TRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTP 374
            R++      +   S   Y    S   Q    P              +   P P+P+   
Sbjct: 376 DRKVDTRKFRSEPRSIFEYEPGKSSILQHERPP-------------PLPTTPTPVPREPG 422

Query: 375 QIPLTGFVARVQENIADSPTPPP----PPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVV 429
           + PL+   +R+ E +  SP+PPP    P P    P    SP  PP  P+DY  + ++ V
Sbjct: 423 RKPLSS--SRLGE-VTGSPSPPPRSGAPTPSSRAPAL--SPTRPPKKPLDYVQDHSSGV 476


>gi|224586846 sorbin and SH3 domain containing 2 isoform 4 [Homo
           sapiens]
          Length = 731

 Score = 66.2 bits (160), Expect = 7e-11
 Identities = 83/356 (23%), Positives = 128/356 (35%), Gaps = 47/356 (13%)

Query: 156 LKAKHGNNQP-ARTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYM 214
           L   H +N P A     S   PP   PP PP+  R     +T     +P         + 
Sbjct: 235 LSKSHSDNSPNAFKDASSPVPPPHVPPPVPPLRPRDR--SSTEKHDWDPPDRKVDTRKFR 292

Query: 215 TSPARLGSQHSPGRTASLNQR-----PRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPP 269
           + P  +  ++ PG+++ L        P T +      G R+   SS +G     P+P PP
Sbjct: 293 SEPRSI-FEYEPGKSSILQHERPPPLPTTPTPVPREPG-RKPLSSSRLGEVTGSPSP-PP 349

Query: 270 TIGPENISVPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTS 329
             G    S   P+ +P  PP  PL  V    +   +       ++ R + R  S+ S  S
Sbjct: 350 RSGAPTPSSRAPALSPTRPPKKPLDYVQDHSSGVFNEASLYQSSIDRSLERPMSSASMAS 409

Query: 330 SGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQENI 389
               RR         ++P V         S S   P         ++ L G    + ++ 
Sbjct: 410 DFRKRR--------KSEPAVGPPRGLGDQSASRTSPG--------RVDLPGSSTTLTKS- 452

Query: 390 ADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDP--YADGDPAWAPKNY 447
                            F  S P  P    D E   +      D    A  +    P+  
Sbjct: 453 -----------------FTSSSPSSPSRAKDRESPRSYSSTLTDMGRSAPRERRGTPEKE 495

Query: 448 IEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESI 503
                A+YD+      ELSF +G  +Y+++K D  WYEG  +   G+FP +YVE +
Sbjct: 496 KLPAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKL 551



 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 34/96 (35%), Positives = 47/96 (48%), Gaps = 8/96 (8%)

Query: 413 PPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNYI---EKVVAIYDYTKDKDDELSFME 469
           P PP P  Y  +    +  N P     P +  +N     E   A+Y+YT   +DEL   E
Sbjct: 639 PDPPIPHSYSSDRIHSLSSNKPQR---PVFTHENIQGGGEPFQALYNYTPRNEDELELRE 695

Query: 470 GAIIYVIKKNDDGWYEGVCNRVT--GLFPGNYVESI 503
             +I V++K DDGW+ G   R    G FPGNYV+ +
Sbjct: 696 SDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 731



 Score = 56.2 bits (134), Expect = 7e-08
 Identities = 83/350 (23%), Positives = 119/350 (34%), Gaps = 67/350 (19%)

Query: 172 SRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPG--RT 229
           SR    T  P  PP SG  T     P   L P +PP  P DY+         HS G    
Sbjct: 336 SRLGEVTGSPSPPPRSGAPTPSSRAP--ALSPTRPPKKPLDYV-------QDHSSGVFNE 386

Query: 230 ASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENISVPPPSGAPPAPP 289
           ASL Q       SS          S+S+         S P +GP    +   S +  +P 
Sbjct: 387 ASLYQ-------SSIDRSLERPMSSASMASDFRKRRKSEPAVGPPR-GLGDQSASRTSPG 438

Query: 290 LAPLLPVSTVIAAP--GSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQP 347
              L   ST +      S+P S      R+  R  S+T +       R    T +    P
Sbjct: 439 RVDLPGSSTTLTKSFTSSSPSSPSRAKDRESPRSYSSTLTDMGRSAPRERRGTPEKEKLP 498

Query: 348 HVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSP-------TPPPPPP 400
                   +Q S  ++        +  +I    +       +   P       TPP    
Sbjct: 499 AKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKLTPPEKAQ 558

Query: 401 PDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKD 460
           P        + PPPP  P +                           I + +A Y++  D
Sbjct: 559 P--------ARPPPPAQPGE---------------------------IGEAIAKYNFNAD 583

Query: 461 KDDELSFMEGAIIYVIKKNDDGWYEGV---CNRVTGLFPGNYVESIMHYT 507
            + ELS  +G  + ++K+ D  WYEG     NR  G+FP +YVE +   T
Sbjct: 584 TNVELSLRKGDRVILLKRVDQNWYEGKIPGTNR-QGIFPVSYVEVVKKNT 632



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 58/239 (24%), Positives = 85/239 (35%), Gaps = 46/239 (19%)

Query: 196 TPYKTLEPVKPPTVPNDYMTSPARLGSQ-HSPGRTASLNQRPRTHSGSSGGSGSRENSGS 254
           T +K +  V  P    D   +P    +  ++P  +A  +   +T +        R  S S
Sbjct: 186 TMFKQIHMVHKPDDDTDMYNTPYTYNAGLYNPPYSAQSHPAAKTQT-------YRPLSKS 238

Query: 255 SSIGIPIAVPTPSPPTIGPENISVPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTM 314
            S   P A    S P        VPPP   PP PPL P    ST            +   
Sbjct: 239 HSDNSPNAFKDASSP--------VPPPHVPPPVPPLRPRDRSST--------EKHDWDPP 282

Query: 315 TRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTP 374
            R++      +   S   Y    S   Q    P              +   P P+P+   
Sbjct: 283 DRKVDTRKFRSEPRSIFEYEPGKSSILQHERPP-------------PLPTTPTPVPREPG 329

Query: 375 QIPLTGFVARVQENIADSPTPPP----PPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVV 429
           + PL+   +R+ E +  SP+PPP    P P    P    SP  PP  P+DY  + ++ V
Sbjct: 330 RKPLSS--SRLGE-VTGSPSPPPRSGAPTPSSRAPAL--SPTRPPKKPLDYVQDHSSGV 383


>gi|47132519 Ras association and pleckstrin homology domains 1
           isoform 1 [Homo sapiens]
          Length = 1250

 Score = 66.2 bits (160), Expect = 7e-11
 Identities = 58/191 (30%), Positives = 75/191 (39%), Gaps = 41/191 (21%)

Query: 252 SGSSSIGIPIAVPTPSPPTIGPENISVPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGS-Q 310
           S    I  P     PSPP   P     PPP   PP PP  P LP  +  +A  +AP   +
Sbjct: 610 SPQPKIVTPYTASQPSPPLPPPPP---PPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVK 666

Query: 311 YGTMTRQISRHNSTTSSTSSGGYRR--TPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPP 368
           Y T+TR         +S  SG   +  TP V    S +P +    L   N + + PPPPP
Sbjct: 667 YSTITRL------QNASQHSGALFKPPTPPVMQSQSVKPQI----LVPPNGV-VPPPPPP 715

Query: 369 MPQLTPQIPLTGF--------------------VARVQENIADSPTPPPPPPPDDIPMFD 408
            P  TP   +                       + +VQ     +P  PPPPPP   P+  
Sbjct: 716 PPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPL-- 773

Query: 409 DSPPPPPPPPV 419
             PP  PP P+
Sbjct: 774 --PPQAPPKPL 782



 Score = 59.3 bits (142), Expect = 8e-09
 Identities = 85/329 (25%), Positives = 126/329 (38%), Gaps = 67/329 (20%)

Query: 165  PARTGT------LSRTNPPTQKPPSPPMSGRGTLGRN----TPYKTLEPVKPPTVPNDYM 214
            PA T T      +++  PPT  PP PP   +     +    +P     PV PPT+P    
Sbjct: 786  PAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQS 845

Query: 215  ---------TSPA-----RLGSQHSPGRTA-SLNQRPRTHSGSSGGSGSRENSGSSSIGI 259
                      SP      ++ SQ  P  T  ++  +P     ++    S     +     
Sbjct: 846  FCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQ 905

Query: 260  PIAVPTPSP--PTIGPENISV--PPPSGAPPAPPLAP---LLPVSTVIAAPG------SA 306
            P ++P PSP  P   PE+  V  PPP    PAPP  P     P      +PG      S+
Sbjct: 906  PSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSS 965

Query: 307  PGSQYGTMTRQISRHNSTTSSTSSGGY--RRTPSVTAQFS--AQPHVNGGPLYSQNSISI 362
            PG +    T Q    NS+  S+S   +   + PSV +  S    P  +G P         
Sbjct: 966  PGGKKPPPTPQ---RNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPA 1022

Query: 363  APPPPPMPQLT----PQIPLTGFVA--------RVQENIADSPTPP-----PPPPPDDIP 405
            APP P    L+    P +   G V+        R ++++ + P+PP     PPPPP+   
Sbjct: 1023 APPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPE--- 1079

Query: 406  MFDDSPPPPPPPPVDYEDEEAAVVQYNDP 434
               + P PP   P  +    +  V   +P
Sbjct: 1080 --TELPLPPIEIPAVFSGNTSPKVAVVNP 1106



 Score = 56.6 bits (135), Expect = 5e-08
 Identities = 74/313 (23%), Positives = 99/313 (31%), Gaps = 60/313 (19%)

Query: 170 TLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRT 229
           T S+ +PP   PP PP           P     P  PP +P+    S            T
Sbjct: 620 TASQPSPPLPPPPPPP----------PPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYST 669

Query: 230 ASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENISVPPPSGAPPAPP 289
            +  Q    HSG+     +     S S+   I VP        P  +  PPP   PP PP
Sbjct: 670 ITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVP--------PNGVVPPPP---PPPPP 718

Query: 290 LAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHV 349
             P   ++ +  AP +    Q+      +  H      T        P         P  
Sbjct: 719 PTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQ-VQHITQVAPPTPPPPPPIPAPLPPQA 777

Query: 350 NGGPLYS----QNSISIAP------PPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPP 399
              PL +     ++ ++AP      PP P P + P      F A         PTPP P 
Sbjct: 778 PPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIP--PSPPTPPVPV 835

Query: 400 PPDDIP---MFDDSPP------------------PPPPPPVDYEDE-----EAAVVQYND 433
           PP  +P    F   PP                  PPPP P   E +      A V   + 
Sbjct: 836 PPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSP 895

Query: 434 PYADGDPAWAPKN 446
           P     P W P +
Sbjct: 896 PAVKAKPKWQPSS 908



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 49/181 (27%), Positives = 63/181 (34%), Gaps = 43/181 (23%)

Query: 261 IAVPTP-SPPTIGPENISVPPPSGAPPAPPLA--PLLPVSTVIAAPGSAPGSQYGTMTRQ 317
           + +P P S  T+ P      PP+  PP PP    P  P S +   P S P          
Sbjct: 783 VTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYI---PPSPPTPPVPVPPPT 839

Query: 318 ISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIP 377
           + +  S  +          PSV  Q ++Q                  PPPP P      P
Sbjct: 840 LPKQQSFCAKPPPSPLSPVPSVVKQIASQF-----------------PPPPTPPAMESQP 882

Query: 378 LTGFVARV--------------QENIADSPTPP-PPPPPDDIPMFDDSPP-----PPPPP 417
           L    A V              Q +    P+P  PPPPP+   +F   PP     PPPPP
Sbjct: 883 LKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPP 942

Query: 418 P 418
           P
Sbjct: 943 P 943



 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 35/124 (28%), Positives = 54/124 (43%), Gaps = 3/124 (2%)

Query: 304 GSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIA 363
           GS+  S   + +   ++ +S  S T   G+ R+ S+ +   ++    G  L   +   + 
Sbjct: 537 GSSSSSIPESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEESSKARME 596

Query: 364 PPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYED 423
               P   L P  PL+     V    A  P+PP PPPP   P     PPPPPPPP+  + 
Sbjct: 597 SMNRPYTSLVP--PLSPQPKIVTPYTASQPSPPLPPPPPPPPP-PPPPPPPPPPPLPSQS 653

Query: 424 EEAA 427
             +A
Sbjct: 654 APSA 657



 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 54/219 (24%), Positives = 79/219 (36%), Gaps = 45/219 (20%)

Query: 262  AVPTPSPPTIGPENISVPPPSGAPPAPPLAPL-LPVSTV------IAAPGSAPGSQYGTM 314
            A PTP+PP    +     P S  PP+PP  P+ +P  T+       A P  +P S   ++
Sbjct: 802  APPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSV 861

Query: 315  TRQISRH---NSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISI--------- 362
             +QI+       T  +  S   +  P+  A  S  P V   P +  +SI +         
Sbjct: 862  VKQIASQFPPPPTPPAMESQPLKPVPANVAPQSP-PAVKAKPKWQPSSIPVPSPDFPPPP 920

Query: 363  ----------------APPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPM 406
                            APPPPP P  +P    +G   +     +      PPP P     
Sbjct: 921  PESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSS 980

Query: 407  FDDSP----PPPPPPPVDYEDEEAAVVQYNDPYADGDPA 441
               S     P P  P VD     + V ++  P   G P+
Sbjct: 981  IKSSSGAEHPEPKRPSVD-----SLVSKFTPPAESGSPS 1014



 Score = 38.5 bits (88), Expect = 0.015
 Identities = 66/301 (21%), Positives = 100/301 (33%), Gaps = 72/301 (23%)

Query: 176  PPTQKPP--SPPMSGRGTLGRNTPYKTLEP--VKPPTVPNDYMTSPARLGSQHSPGRTAS 231
            PP   PP  SP     G+ G+ T  KT  P   KPP  P    +  +  G++H   +   
Sbjct: 938  PPPPPPPTASPTPDKSGSPGKKTS-KTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPK--- 993

Query: 232  LNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENISVP------------ 279
               RP   S  S  +   E+   S   +P     P P  +    +++P            
Sbjct: 994  ---RPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKA 1050

Query: 280  ----------------PPSGA--PPAPPLAPL-LPVSTVIAAPGSAPGSQYGTMTRQISR 320
                            PPS +  PP PP   L LP       P   P    G  + +++ 
Sbjct: 1051 PVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLP-------PIEIPAVFSGNTSPKVAV 1103

Query: 321  HNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLT- 379
             N      S    ++ P  T     +P  N     +Q  IS     P M  + PQ+P + 
Sbjct: 1104 VNPQPQQWSKMSVKKAPPPT-----RPKRNDSTRLTQAEIS---EQPTMATVVPQVPTSP 1155

Query: 380  --------GFVARVQENIA------DSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEE 425
                    GF+A +   +                  +     DD   PPPPP +  + ++
Sbjct: 1156 KSSLSVQPGFLADLNRTLQRKSITRHGSLSSRMSRAEPTATMDDMALPPPPPELLSDQQK 1215

Query: 426  A 426
            A
Sbjct: 1216 A 1216



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 65/276 (23%), Positives = 89/276 (32%), Gaps = 83/276 (30%)

Query: 165  PARTGTLSR-TNPPTQKPP------------------------SPPMSGRGTLG----RN 195
            PA +G+ S+ T PP   PP                        +P +SGRG        +
Sbjct: 1007 PAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPS 1066

Query: 196  TPYKTLEPVKPPT--VPNDYMTSPARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSG 253
             P  +  P  PP   +P   +  PA      SP + A +N +P+  S  S          
Sbjct: 1067 PPSDSDFPPPPPETELPLPPIEIPAVFSGNTSP-KVAVVNPQPQQWSKMS---------- 1115

Query: 254  SSSIGIPIAVPTPSPPTIGPENISV--------PPPSGAPPAPPLAPLLPVSTVIAAPGS 305
                     V    PPT    N S           P+ A   P + P  P S++   PG 
Sbjct: 1116 ---------VKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQV-PTSPKSSLSVQPGF 1165

Query: 306  APGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPP 365
                      + I+RH S +S  S    R  P+ T                     +A P
Sbjct: 1166 LADLNRTLQRKSITRHGSLSSRMS----RAEPTATMD------------------DMALP 1203

Query: 366  PPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPP 401
            PPP P+L       G+        A     PPP PP
Sbjct: 1204 PPP-PELLSDQQKAGYGGSHISGYATLRRGPPPAPP 1238


>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
          Length = 1670

 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 30/62 (48%), Positives = 44/62 (70%), Gaps = 3/62 (4%)

Query: 440  PAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNY 499
            PA+ P   + +V+A+YDY  + +DELSF +G +I V+ K+D  W++G  N VTGLFP NY
Sbjct: 1097 PAFHP---VCQVIAMYDYAANNEDELSFSKGQLINVMNKDDPDWWQGEINGVTGLFPSNY 1153

Query: 500  VE 501
            V+
Sbjct: 1154 VK 1155



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 6/87 (6%)

Query: 415  PPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIY 474
            P   V  E+ EA     N       P  A  +  E+ +A+Y Y+  +  +L+F EG  I 
Sbjct: 928  PGSEVKREEPEALYAAVNKK-----PTSAAYSVGEEYIALYPYSSVEPGDLTFTEGEEIL 982

Query: 475  VIKKNDDGWYEGVCNRVTGLFPGNYVE 501
            V +K D  W+ G     +G+FP NYV+
Sbjct: 983  VTQK-DGEWWTGSIGDRSGIFPSNYVK 1008



 Score = 36.6 bits (83), Expect = 0.055
 Identities = 21/53 (39%), Positives = 27/53 (50%), Gaps = 2/53 (3%)

Query: 453 AIYDYTKDKDDELSFMEGAIIYVIKK--NDDGWYEGVCNRVTGLFPGNYVESI 503
           A+Y +     DE+SF  G II V +K   + GW  G      G FP NYVE +
Sbjct: 737 ALYPFEARNHDEMSFNSGDIIQVDEKTVGEPGWLYGSFQGNFGWFPCNYVEKM 789



 Score = 35.0 bits (79), Expect = 0.16
 Identities = 16/50 (32%), Positives = 26/50 (52%), Gaps = 5/50 (10%)

Query: 457  YTKDKDDELSFMEGAIIYVIKKNDDGWYEGVC-----NRVTGLFPGNYVE 501
            Y     ++LS   G +I ++KKN  GW++G        R  G FP ++V+
Sbjct: 1037 YVASGSEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQKGWFPASHVK 1086



 Score = 33.9 bits (76), Expect = 0.36
 Identities = 18/54 (33%), Positives = 32/54 (59%), Gaps = 1/54 (1%)

Query: 450 KVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESI 503
           K  A+  +T  KD+ L+F +  II V+++ ++ W+ G  +   G FP +YV+ I
Sbjct: 875 KAQALCSWTAKKDNHLNFSKHDIITVLEQQENWWF-GEVHGGRGWFPKSYVKII 927


>gi|194294521 intersectin 2 isoform 1 [Homo sapiens]
          Length = 1697

 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 30/62 (48%), Positives = 44/62 (70%), Gaps = 3/62 (4%)

Query: 440  PAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNY 499
            PA+ P   + +V+A+YDY  + +DELSF +G +I V+ K+D  W++G  N VTGLFP NY
Sbjct: 1124 PAFHP---VCQVIAMYDYAANNEDELSFSKGQLINVMNKDDPDWWQGEINGVTGLFPSNY 1180

Query: 500  VE 501
            V+
Sbjct: 1181 VK 1182



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 6/87 (6%)

Query: 415  PPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIY 474
            P   V  E+ EA     N       P  A  +  E+ +A+Y Y+  +  +L+F EG  I 
Sbjct: 955  PGSEVKREEPEALYAAVNKK-----PTSAAYSVGEEYIALYPYSSVEPGDLTFTEGEEIL 1009

Query: 475  VIKKNDDGWYEGVCNRVTGLFPGNYVE 501
            V +K D  W+ G     +G+FP NYV+
Sbjct: 1010 VTQK-DGEWWTGSIGDRSGIFPSNYVK 1035



 Score = 36.6 bits (83), Expect = 0.055
 Identities = 21/53 (39%), Positives = 27/53 (50%), Gaps = 2/53 (3%)

Query: 453 AIYDYTKDKDDELSFMEGAIIYVIKK--NDDGWYEGVCNRVTGLFPGNYVESI 503
           A+Y +     DE+SF  G II V +K   + GW  G      G FP NYVE +
Sbjct: 764 ALYPFEARNHDEMSFNSGDIIQVDEKTVGEPGWLYGSFQGNFGWFPCNYVEKM 816



 Score = 35.0 bits (79), Expect = 0.16
 Identities = 16/50 (32%), Positives = 26/50 (52%), Gaps = 5/50 (10%)

Query: 457  YTKDKDDELSFMEGAIIYVIKKNDDGWYEGVC-----NRVTGLFPGNYVE 501
            Y     ++LS   G +I ++KKN  GW++G        R  G FP ++V+
Sbjct: 1064 YVASGSEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQKGWFPASHVK 1113



 Score = 33.9 bits (76), Expect = 0.36
 Identities = 18/54 (33%), Positives = 32/54 (59%), Gaps = 1/54 (1%)

Query: 450 KVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESI 503
           K  A+  +T  KD+ L+F +  II V+++ ++ W+ G  +   G FP +YV+ I
Sbjct: 902 KAQALCSWTAKKDNHLNFSKHDIITVLEQQENWWF-GEVHGGRGWFPKSYVKII 954


>gi|194294525 intersectin 2 isoform 2 [Homo sapiens]
          Length = 1249

 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 30/62 (48%), Positives = 44/62 (70%), Gaps = 3/62 (4%)

Query: 440  PAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNY 499
            PA+ P   + +V+A+YDY  + +DELSF +G +I V+ K+D  W++G  N VTGLFP NY
Sbjct: 1124 PAFHP---VCQVIAMYDYAANNEDELSFSKGQLINVMNKDDPDWWQGEINGVTGLFPSNY 1180

Query: 500  VE 501
            V+
Sbjct: 1181 VK 1182



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 6/87 (6%)

Query: 415  PPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIY 474
            P   V  E+ EA     N       P  A  +  E+ +A+Y Y+  +  +L+F EG  I 
Sbjct: 955  PGSEVKREEPEALYAAVNKK-----PTSAAYSVGEEYIALYPYSSVEPGDLTFTEGEEIL 1009

Query: 475  VIKKNDDGWYEGVCNRVTGLFPGNYVE 501
            V +K D  W+ G     +G+FP NYV+
Sbjct: 1010 VTQK-DGEWWTGSIGDRSGIFPSNYVK 1035



 Score = 36.6 bits (83), Expect = 0.055
 Identities = 21/53 (39%), Positives = 27/53 (50%), Gaps = 2/53 (3%)

Query: 453 AIYDYTKDKDDELSFMEGAIIYVIKK--NDDGWYEGVCNRVTGLFPGNYVESI 503
           A+Y +     DE+SF  G II V +K   + GW  G      G FP NYVE +
Sbjct: 764 ALYPFEARNHDEMSFNSGDIIQVDEKTVGEPGWLYGSFQGNFGWFPCNYVEKM 816



 Score = 35.0 bits (79), Expect = 0.16
 Identities = 16/50 (32%), Positives = 26/50 (52%), Gaps = 5/50 (10%)

Query: 457  YTKDKDDELSFMEGAIIYVIKKNDDGWYEGVC-----NRVTGLFPGNYVE 501
            Y     ++LS   G +I ++KKN  GW++G        R  G FP ++V+
Sbjct: 1064 YVASGSEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQKGWFPASHVK 1113



 Score = 33.9 bits (76), Expect = 0.36
 Identities = 18/54 (33%), Positives = 32/54 (59%), Gaps = 1/54 (1%)

Query: 450 KVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESI 503
           K  A+  +T  KD+ L+F +  II V+++ ++ W+ G  +   G FP +YV+ I
Sbjct: 902 KAQALCSWTAKKDNHLNFSKHDIITVLEQQENWWF-GEVHGGRGWFPKSYVKII 954


>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
          Length = 1094

 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 72/244 (29%), Positives = 97/244 (39%), Gaps = 38/244 (15%)

Query: 184 PPMSGRGTLGRNTPYK------TLEP---VKPPTVPNDYMT-SPARLGSQHSPGRTASLN 233
           PP S   TL  ++ Y       TL P     PP  P       P R+ S  SPG + S  
Sbjct: 570 PPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVS-- 627

Query: 234 QRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENISVPPPSGAPPAPPLAPL 293
                 S +S  S S + + S   G  I  P      I P +  VP P   PP+ P +P 
Sbjct: 628 -----SSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVI-PPHPKVPAPFSPPPSKPRSPN 681

Query: 294 LPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGP 353
            P +  +AAP   PG      T   S  +  T  T+    + +P ++   S  P  +  P
Sbjct: 682 -PAAPALAAPAVVPGP---VSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPP--SPPP 735

Query: 354 LYSQNSISIAPPPPPM--PQLTPQIPLTGFVARVQENIADSPTPPPPPP---PDDIPMFD 408
            Y        PPPPP   P++  + P     A  +E + D   PPPPPP     D+ M D
Sbjct: 736 SYH-------PPPPPTKKPEVVVEAPSASETA--EEPLQDPNWPPPPPPAPEEQDLSMAD 786

Query: 409 DSPP 412
             PP
Sbjct: 787 FPPP 790



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 56/225 (24%), Positives = 81/225 (36%), Gaps = 19/225 (8%)

Query: 204  VKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAV 263
            ++PP  P+     PA   +  +PG  A L Q+      S GG   RE+     +G P+  
Sbjct: 827  IQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPV-GCSKGGGPPRED-----VGAPLVT 880

Query: 264  PTPSPPTIGPENISVPPPSGAP-----PAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQI 318
            P+           SV  P GAP     P+ P  PL    +  A+P  AP S      R  
Sbjct: 881  PSLLQMV---RLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLK 937

Query: 319  SRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNS--ISIAPPPPPMPQLTPQI 376
            +   + +   SS      P    +    P      ++S+ S  + +  P  P  Q   Q 
Sbjct: 938  ACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQR 997

Query: 377  PLTGFVARVQEN---IADSPTPPPPPPPDDIPMFDDSPPPPPPPP 418
             L   +  + E     A   +P  PPP    P     PP  P  P
Sbjct: 998  NLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYP 1042



 Score = 31.2 bits (69), Expect = 2.3
 Identities = 37/160 (23%), Positives = 58/160 (36%), Gaps = 24/160 (15%)

Query: 169 GTLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQH---- 224
           G +S T+   Q PP+P  +   T  + +P  + +   PP+ P  Y   P           
Sbjct: 695 GPVSTTDASPQSPPTPQTTL--TPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVE 752

Query: 225 SPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIP--------IAVPTPSPPTIGPENI 276
           +P  + +  +  +  +       + E    S    P        +A P P+ P+  PE +
Sbjct: 753 APSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELV 812

Query: 277 SVPPPSGA--------PPAPPLAPLLPVSTVIAAPGSAPG 308
           S P  S +        PP  P  P  P     A   SAPG
Sbjct: 813 SSPAASSSSATALQIQPPGSPDPP--PAPPAPAPASSAPG 850


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 70/247 (28%), Positives = 88/247 (35%), Gaps = 59/247 (23%)

Query: 175 NPPTQKPPSPPMSGRGTLGRNTP-YKTLEPVK-PPTVPNDYMTSPARLGSQHSPGRTA-S 231
           +PP Q  PSPP+S   T     P    L P++ PP+ P     SP    S  +P   A  
Sbjct: 600 SPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVH 659

Query: 232 LNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENISVPPPSGAPPAPPLA 291
           L Q P +   S                 P+  P  SPP   P + S  PPS APP+    
Sbjct: 660 LLQAPFSPPPSP----------------PVQAPF-SPPASPPVSPSATPPSQAPPSLAAP 702

Query: 292 PLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNG 351
           PL         P S P S                          +PS T    A P +  
Sbjct: 703 PL-------QVPPSPPASP-----------------------PMSPSATPPPQAPPPLAA 732

Query: 352 GPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSP 411
            PL       + P PP  P ++P         RV   +A  P   PP PP  +PM   + 
Sbjct: 733 PPL------QVPPSPPASPPMSPSATPP---PRVPPLLAAPPLQVPPSPPASLPMSPLAK 783

Query: 412 PPPPPPP 418
           PPP  PP
Sbjct: 784 PPPQAPP 790



 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 74/271 (27%), Positives = 107/271 (39%), Gaps = 39/271 (14%)

Query: 176 PPTQKPPS---PPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASL 232
           PP+Q PPS   PPM    +L      +T+ P++ P      +TSP+ L +  SP   +SL
Sbjct: 364 PPSQAPPSMTTPPMQAPPSL------QTIPPIQVP----HSLTSPS-LQAPPSPLALSSL 412

Query: 233 NQRPRTHSGSSGGSGS------RENSGS-SSIGIPIAVPTPSPPTIGPENISVPPP---S 282
                  S +   + S      R+   S +S   P + P  SPP   P ++   PP   S
Sbjct: 413 QATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTS 472

Query: 283 GAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPS--VT 340
            +P   PL+  L +  + A    A  S    ++  I     T SS +    +  P+   T
Sbjct: 473 LSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTT 532

Query: 341 AQFSAQPHVNGGPLYSQNS------ISIAPPPPPMPQLTPQIPLTGFVARVQENIADSPT 394
                 P +   PL + ++      +   P P P P   P  PLT        +IA  P 
Sbjct: 533 PPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPP 592

Query: 395 PPPP----PPPDDIPMFDDSP---PPPPPPP 418
             PP    PP   +P    SP   PPP  PP
Sbjct: 593 QAPPALASPPLQGLPSPPLSPLATPPPQAPP 623



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 65/234 (27%), Positives = 83/234 (35%), Gaps = 61/234 (26%)

Query: 176 PPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPT--VPNDYMTSPARLGSQHSPGRTASLN 233
           PP Q PPSPP S   +     P +   P+  P   VP     SP    S   P R   L 
Sbjct: 702 PPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLL 761

Query: 234 QRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENISVPPPSGAPPAPPLAPL 293
             P                       P+ VP PSPP   P +    PP  APPA    PL
Sbjct: 762 AAP-----------------------PLQVP-PSPPASLPMSPLAKPPPQAPPALATPPL 797

Query: 294 LPVSTVIAA-PGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFS--AQPHVN 350
             + +  A+ PG AP S                           PS +   S  A P   
Sbjct: 798 QALPSPPASFPGQAPFS---------------------------PSASLPMSPLATPPPQ 830

Query: 351 GGPLYSQNSISIAPPPPPMPQL-TPQIPLT----GFVARVQENIADSPTPPPPP 399
             P+ +   + + P PP  P L  P+ P T      V+  +  +A +P PPPPP
Sbjct: 831 APPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPP 884



 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 84/300 (28%), Positives = 111/300 (37%), Gaps = 59/300 (19%)

Query: 165 PARTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPN--DYMTSPARLGS 222
           P R+   S  NP ++    PP SGRG   R  P K   P  P + P      T P  LG 
Sbjct: 79  PTRSAGTSSRNPASR----PPASGRGE--RAPPAKNTSP-GPVSSPGRASGTTRPGPLGQ 131

Query: 223 Q----------------HSPGRTASLNQRPRTHSGSSGGSGS-----RENSGSSSIGIPI 261
           +                 +P R+A      R  SG + G+ S     R  +  + +G+P 
Sbjct: 132 KGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPR 191

Query: 262 AVPT--PSPPTIGPENI-------SVPPPSGAPPAPPLA------PLLPVSTVIAAPGSA 306
             P+  P PPT GP          S   PS A    P A      P     +  A P S+
Sbjct: 192 PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSS 251

Query: 307 PGSQYGTMTRQISRHNSTTSSTSSGGYR--RTPSVTA-QFSAQPHVNGGPLYSQNSISIA 363
           P ++ G   R   R  +  S     G +  R P VT  +  A P +  GPL   +S  +A
Sbjct: 252 P-ARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL--GPL---SSSPLA 305

Query: 364 PPPPPMPQLTPQIPLTGFVARVQENIADSP---TPPP--PPPPDDIPMFDDSPPPPPPPP 418
            P P   +  P  P       +   +  SP   TP P  PP P   P     P PP  PP
Sbjct: 306 TPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPP 365



 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 78/320 (24%), Positives = 107/320 (33%), Gaps = 81/320 (25%)

Query: 169 GTLSRTNPPTQKPPSPPMSGR----GT-LGRNTPYKTLEPVKPPTVP-------NDYMTS 216
           G    T+ PT   PSP M+ R    GT +G   P  +  P  P   P       +++ T+
Sbjct: 159 GARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTT 218

Query: 217 PARLGSQHSPGRTASLNQRPRTHSGSSGGS--GSRENSGSSSIGIPIA------------ 262
                ++  P     L QRP + S SS  +   S   SG S+ G P A            
Sbjct: 219 EPSPAARRRPSAGGGL-QRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGL 277

Query: 263 --------------------------VPTPSP------PTIGPENISVPPPSGAPPAPPL 290
                                     + TPSP      P   P+N + P P+  PP+PPL
Sbjct: 278 QALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPL 337

Query: 291 APLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVN 350
           A  LP+         AP S     + Q       T  + +     TP + A  S Q    
Sbjct: 338 ATPLPL---------APPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPP 388

Query: 351 GGPLYSQNSISIAPPPPPM-------------PQLTPQIPLTGFVARVQENIADSPTPPP 397
               +S  S S+  PP P+             P L           R  +    SP+ P 
Sbjct: 389 IQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPA 448

Query: 398 PPPPDDIPMFDDSPPPPPPP 417
             PPD  P+      P  PP
Sbjct: 449 STPPDSPPLQAPLSLPASPP 468



 Score = 29.3 bits (64), Expect = 8.8
 Identities = 44/188 (23%), Positives = 63/188 (33%), Gaps = 34/188 (18%)

Query: 267 SPPTIGPENISVPPPSGAPPAPPLAP-LLPVSTVIAAPGSAP------GSQYGTMTRQIS 319
           +P    P  ++  PP    P PP+ P  L V     A G  P      G    T+     
Sbjct: 16  TPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAP 75

Query: 320 RHNSTTSS-TSSGGYRRTPSVTAQFSAQP---HVNGGPLYSQNSISIAPPPPPMPQLTPQ 375
           R   T S+ TSS      P  + +    P   + + GP+ S    S    P P+ Q   +
Sbjct: 76  RAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLR 135

Query: 376 IPLTGFVARVQENIA--------------DSPTPPPPPPP---------DDIPMFDDSPP 412
           I     VAR +   A                PTP  P P           ++ +   +P 
Sbjct: 136 ISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPS 195

Query: 413 PPPPPPVD 420
             P PP +
Sbjct: 196 ARPRPPTE 203


>gi|46094081 development and differentiation enhancing factor 1 [Homo
            sapiens]
          Length = 1129

 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 101/388 (26%), Positives = 140/388 (36%), Gaps = 96/388 (24%)

Query: 168  TGTLSRTNPPTQKPPSPPMS-GRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSP 226
            T T S T+P T+ PP PP + G+G  G   P  TL P+   T       S  R      P
Sbjct: 778  TSTDSPTSPTTEAPPLPPRNAGKGPTG---PPSTL-PLSTQTSSGSSTLSKKR-PPPPPP 832

Query: 227  G--RTASLNQRPRTHS---------GSSGGSGSRENSGSSSIGIPIAVPTPSPPT-IGP- 273
            G  RT S    P  H          G+ GG  S   + +   G+     T S  T +GP 
Sbjct: 833  GHKRTLSDPPSPLPHGPPNKGAVPWGNDGGPSSSSKTTNKFEGLSQQSSTSSAKTALGPR 892

Query: 274  -------------------ENISVPPP--------SGAPPAPPLAPLLPVSTVIAAPGSA 306
                               +  ++PP         +  P  PP   L P  T +A     
Sbjct: 893  VLPKLPQKVALRKTDHLSLDKATIPPEIFQKSSQLAELPQKPPPGDLPPKPTELA----- 947

Query: 307  PGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPP 366
            P  Q G +                      P    +   +P +  G L  +  +S  PP 
Sbjct: 948  PKPQIGDL----------------------PPKPGELPPKPQL--GDLPPKPQLSDLPPK 983

Query: 367  PPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYED--E 424
            P M  L P+  L   +A+ Q         P    P ++ +   S P    P V   D  +
Sbjct: 984  PQMKDLPPKPQLGDLLAKSQTG----DVSPKAQQPSEVTL--KSHPLDLSPNVQSRDAIQ 1037

Query: 425  EAAVVQYND--PYADGDPAWAP------KNYIEKVVAIYDYTKDKDDELSFMEGAIIYVI 476
            + A    ND  P     P   P      KN + +V  IYD   D DDEL+F+EG +I V 
Sbjct: 1038 KQASEDSNDLTPTLPETPVPLPRKINTGKNKVRRVKTIYDCQADNDDELTFIEGEVIIVT 1097

Query: 477  KKNDDGWY----EGVCNRVTGLFPGNYV 500
             + D  W+    EG   R  G+FP ++V
Sbjct: 1098 GEEDQEWWIGHIEGQPER-KGVFPVSFV 1124


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 63.5 bits (153), Expect = 4e-10
 Identities = 77/270 (28%), Positives = 106/270 (39%), Gaps = 42/270 (15%)

Query: 163 NQPARTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTV-PNDYMTSPARLG 221
           + PAR+G  +R  P     PS P             K L+ ++PP V P     +PA   
Sbjct: 241 SSPARSGPSARGTPRAPAHPSQPKP-----------KGLQALRPPQVTPPRKDAAPALGP 289

Query: 222 SQHSPGRTASLNQRPRTHSGSS-----GGSGSRENSGSSSIGIPIAVPT----PSPPTIG 272
              SP  T S +  P   +  S         +  +  ++S+G P    T    PSPP + 
Sbjct: 290 LSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPP-LS 348

Query: 273 PENISVPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGG 332
           P  ++ PPP     APP   L P+    + P S P S   T + Q     +     +   
Sbjct: 349 P--LATPPPQ----APPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS 402

Query: 333 YRRTPSVTAQFS--AQPHVNGGPLY-SQNSISIAPPPPPMPQLTPQIPLTGFVARVQENI 389
              +P V A FS  A P V+      SQ   S+A PP  +P   P  P           +
Sbjct: 403 PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP----------PM 452

Query: 390 ADSPTPPPP-PPPDDIPMFDDSPPPPPPPP 418
           + S TPPP  PPP   P    + PPP  PP
Sbjct: 453 SPSATPPPQAPPPLAAPPLQLAKPPPQAPP 482



 Score = 56.6 bits (135), Expect = 5e-08
 Identities = 71/270 (26%), Positives = 98/270 (36%), Gaps = 60/270 (22%)

Query: 169 GTLSRTNPPTQKPPSPPMSGR----GT-LGRNTPYKTLEPVKPPTVP-------NDYMTS 216
           G    T+ PT   PSP M+ R    GT +G   P  +  P  P   P       +++ T+
Sbjct: 150 GARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTT 209

Query: 217 PARLGSQHSPGRTASLNQRPRTHSGSSGGS--GSRENSGSSSIGIPIAVPTPSPPTIGPE 274
                ++  P     L QRP + S SS  +   S   SG S+ G P A   PS P   P+
Sbjct: 210 EPSPAARRRPSAGGGL-QRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPK--PK 266

Query: 275 NI-SVPPPSGAPP----APPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTS 329
            + ++ PP   PP    AP L PL        +P + P                  S ++
Sbjct: 267 GLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPP------------------SPSA 308

Query: 330 SGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQENI 389
               +  PS  A   +Q   + G    Q + S  P PP  P  TP               
Sbjct: 309 PPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATP--------------- 353

Query: 390 ADSPTPPPPPPPDDIPMFDDSPPPPPPPPV 419
                PP  PP   +P     P PP  PP+
Sbjct: 354 -----PPQAPPALALPPLQAPPSPPASPPL 378



 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 63/232 (27%), Positives = 88/232 (37%), Gaps = 27/232 (11%)

Query: 176 PPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQR 235
           PP Q PPSPP S        +P  T  P  P  +    + +P       SP   A  +  
Sbjct: 364 PPLQAPPSPPASPP-----LSPLATPSPQAPNALAVHLLQAP--FSPPPSPPVQAPFS-- 414

Query: 236 PRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENISVPPPSGAPP---APPLAP 292
           P      S  +     +  S    P+ VP PSPP   P + S  PP  APP   APPL  
Sbjct: 415 PPASPPVSPSATPPSQAPPSLAAPPLQVP-PSPPASPPMSPSATPPPQAPPPLAAPPLQL 473

Query: 293 LLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGG 352
             P       P  AP +      + +   +   S      +  + S+     A P     
Sbjct: 474 AKP-------PPQAPPALATPPLQALP--SPPASFPGQAPFSPSASLPMSPLATPPPQAP 524

Query: 353 PLYSQNSISIAPPPPPMPQL-TPQIPLT----GFVARVQENIADSPTPPPPP 399
           P+ +   + + P PP  P L  P+ P T      V+  +  +A +P PPPPP
Sbjct: 525 PVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPP 576



 Score = 39.3 bits (90), Expect = 0.009
 Identities = 50/199 (25%), Positives = 67/199 (33%), Gaps = 23/199 (11%)

Query: 214 MTSPARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGP 273
           + +P   GS   P        R    +G+ G     E +G    GI  A    S P  GP
Sbjct: 24  LLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAG----GIGGATIPESAPRAGP 79

Query: 274 ENISVPPPSG----APPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTS 329
              S PP SG    APPA   +P       +++PG A G+       Q     S   + +
Sbjct: 80  TRTSRPPASGRGERAPPAKNTSP-----GPVSSPGRASGTTRPGPLGQKGLRISAEETVA 134

Query: 330 SGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPP----------PPPMPQLTPQIPLT 379
            G     P  +A  +       GP     S ++A            P P P   P+ P  
Sbjct: 135 RGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE 194

Query: 380 GFVARVQENIADSPTPPPP 398
           G    V      S T P P
Sbjct: 195 GPRKSVSSASEHSTTEPSP 213


>gi|18959210 WIRE protein [Homo sapiens]
          Length = 440

 Score = 63.2 bits (152), Expect = 6e-10
 Identities = 76/290 (26%), Positives = 97/290 (33%), Gaps = 72/290 (24%)

Query: 176 PPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQR 235
           P  Q+P  P +S   T   +T  K      PP  P     +P      HS    A   ++
Sbjct: 149 PRMQRPSLPDLSRPNTTS-STGMKHSSSAPPPPPPGRRANAPPTPLPMHSSKAPAYNREK 207

Query: 236 PRTHSGSSGGSGSRENSGSSSIGIPIAV-PTPSPPTI--GPENISV---PPPSGAPPAPP 289
           P   +      G R + G      P  V P PSP  I  GP   S+   PPP   PP  P
Sbjct: 208 PLPPT-----PGQRLHPGREGPPAPPPVKPPPSPVNIRTGPSGQSLAPPPPPYRQPPGVP 262

Query: 290 LAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHV 349
             P  P +       SAP            RHNS         +R+TP      +  P  
Sbjct: 263 NGPSSPTNE------SAPELP--------QRHNSL--------HRKTPGPVRGLAPPPPT 300

Query: 350 NGGPLYSQN----------SISIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPP- 398
           +  P    N          S   APPPPP        P+      ++    D+P PPPP 
Sbjct: 301 SASPSLLSNRPPPPARDPPSRGAAPPPPP--------PV------IRNGARDAPPPPPPY 346

Query: 399 -------------PPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPY 435
                        PPP         PPPPPP    + D    V  + D +
Sbjct: 347 RMHGSEPPSRGKPPPPPSRTPAGPPPPPPPPLRNGHRDSITTVRSFLDDF 396



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 54/214 (25%), Positives = 78/214 (36%), Gaps = 43/214 (20%)

Query: 228 RTASLNQRPRTHSGS--SGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENISVPPPSGAP 285
           R+A + ++P+  SG   SGG+  +   G    G+    P  +    G EN++  P    P
Sbjct: 59  RSAPILEKPKGSSGGYGSGGAALQPKGGLFQGGVLKLRPVGAKD--GSENLAGKPALQIP 116

Query: 286 PAPPLAPLLPVSTVIAAPGSAPGSQYGTMTR----------QISRHNSTTSS----TSSG 331
            +   AP  PVS     P     S   ++             +SR N+T+S+    +SS 
Sbjct: 117 SSRAAAPRPPVSAASGRPQDDTDSSRASLPELPRMQRPSLPDLSRPNTTSSTGMKHSSSA 176

Query: 332 GYRRTPSVTAQFSAQP---HVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQEN 388
                P   A     P   H +  P Y++       P PP P             R+   
Sbjct: 177 PPPPPPGRRANAPPTPLPMHSSKAPAYNREK-----PLPPTPG-----------QRLHPG 220

Query: 389 IADSPTPPP-PPPPDDI-----PMFDDSPPPPPP 416
               P PPP  PPP  +     P      PPPPP
Sbjct: 221 REGPPAPPPVKPPPSPVNIRTGPSGQSLAPPPPP 254



 Score = 33.5 bits (75), Expect = 0.47
 Identities = 14/30 (46%), Positives = 16/30 (53%), Gaps = 10/30 (33%)

Query: 393 PTPPPPPPPDDIPMFDDSPPPPPPPPVDYE 422
           P PPPPPPP          P PPPPP  ++
Sbjct: 2   PIPPPPPPP----------PGPPPPPTFHQ 21


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 63.2 bits (152), Expect = 6e-10
 Identities = 74/286 (25%), Positives = 98/286 (34%), Gaps = 65/286 (22%)

Query: 173  RTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKP--PTVPNDYMTSPARLGSQHSPGRTA 230
            R  P  Q   +PP+S   ++  + P + L+P  P  P VP+   +    LG       + 
Sbjct: 1294 RHPPLYQAGLTPPLSPPKSVPPSVPARGLQPQPPATPAVPHPPPSGAFGLGGALEAAESE 1353

Query: 231  SLN------------------QRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIG 272
             L                   +   + S     S ++      SI   I+     PP  G
Sbjct: 1354 GLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISA-LDDPPLAG 1412

Query: 273  PENISVPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGG 332
            P++ S P        PPLAP   V      PG    +  GT    +       +      
Sbjct: 1413 PKDTSTPD------GPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPP---- 1462

Query: 333  YRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADS 392
                P+ T Q    P                PPPPP P L    PL      V    +  
Sbjct: 1463 ----PAPTPQPQPPP----------------PPPPPQPALPSPPPL------VAPTPSSP 1496

Query: 393  PTPP-PPPPPDDIPMFDDSPPPPPPP---PVDYEDEEAAVVQYNDP 434
            P PP PPPPP  +P    SPPPPPPP   P+    EE A     DP
Sbjct: 1497 PPPPLPPPPPPAMP----SPPPPPPPAAAPLAAPPEEPAAPSPEDP 1538



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 57/221 (25%), Positives = 76/221 (34%), Gaps = 47/221 (21%)

Query: 216 SPARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPEN 275
           SP+   + H+PG T          SG+  GS +  +S + S          S P   P +
Sbjct: 115 SPSWQTAMHTPGPTELFI------SGALPGSSTFPSSSALS-AYQHPASFGSRPFPVPSS 167

Query: 276 ISVPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRR 335
           +S+  P  +PPA  L  L P   +   P  AP           +  +S      +GG   
Sbjct: 168 LSLQDPPFSPPANGL--LSPHDVLHLKPSQAP-----------TVPSSLGFERLAGGGVL 214

Query: 336 TPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSP-- 393
            P+        P+  G P          PPPPP    T    L    A        SP  
Sbjct: 215 GPAGLGPAQTPPYRPGPP---------DPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQL 265

Query: 394 ------TPPPPPPPDDIPMFD----------DSPPPPPPPP 418
                  P PPPP   +P  D           + PPPPPPP
Sbjct: 266 YNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPP 306



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 77/319 (24%), Positives = 102/319 (31%), Gaps = 71/319 (22%)

Query: 150 GHGVKWLKAKHGNNQPARTGTLSRTNPPTQKPPS---PPMSGRGTLGRNTPYKTLEPV-- 204
           GHG  W  +  G    A    + R   P Q PP+   PP  G G+ G   P K L  V  
Sbjct: 543 GHGGGWGPSSLGGGGEASPSHIIR---PLQSPPATGRPP--GVGSPG--APGKYLSSVLA 595

Query: 205 -KPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAV 263
             P   P    +  A  G     G  + L   P        G    E +      I   +
Sbjct: 596 SAPFLAPPGAGSYAAGAGGYKGKGDGSELLAGP--------GGPPAERTEDEEFLIQHLL 647

Query: 264 PTPSPP-TIGPENI-------------SVPPPSGAPPAPP--LAPLLP----VSTVIAAP 303
             PSPP T G + +                  +G PP  P  LA   P    + +VI   
Sbjct: 648 QAPSPPRTSGADGLVGEDGAADASKGLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIRTS 707

Query: 304 GSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIA 363
            S        +   + R          GG   TP   A  ++  H   G       +  +
Sbjct: 708 ASLDEGATAALELGLGRLKEKKKGPERGG--ETPEGLA--TSVVHYGAGAKELGAFLQKS 763

Query: 364 PPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMF---------------- 407
           PPPPP    + Q    G +  ++    D P   PPPPP  +P                  
Sbjct: 764 PPPPPPTAQSTQPTPHGLL--LEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGV 821

Query: 408 --------DDSPPPPPPPP 418
                   D +P PPPPPP
Sbjct: 822 HLLEPATRDGAPQPPPPPP 840



 Score = 36.2 bits (82), Expect = 0.072
 Identities = 39/138 (28%), Positives = 50/138 (36%), Gaps = 29/138 (21%)

Query: 337 PSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQI--------PLTGFVA----- 383
           P  TAQ S QP  +G  L +         PPP PQL P +        P    V      
Sbjct: 767 PPPTAQ-STQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLE 825

Query: 384 RVQENIADSPTPPPPPPPDDIPM----------FDDSPPPPPPPPVDYEDEEAAVVQYND 433
               + A  P PPPPPPP  +P+           + + P P   P +  D   A+ +   
Sbjct: 826 PATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLG 885

Query: 434 -----PYADGDPAWAPKN 446
                P A GD    P N
Sbjct: 886 ALEPLPPAPGDTGVGPPN 903



 Score = 34.7 bits (78), Expect = 0.21
 Identities = 36/134 (26%), Positives = 47/134 (35%), Gaps = 16/134 (11%)

Query: 176  PPTQKPPSPPMSGRGTLGRN-TPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQ 234
            P    P  PP+ G  +   N TP   L   KPP  P    T   +      P + A  + 
Sbjct: 1426 PAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSP 1485

Query: 235  RPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENISVPPPSGAP-PAPPLAPL 293
             P               + + S   P  +P P PP + P     PPP+ AP  APP  P 
Sbjct: 1486 PPLV-------------APTPSSPPPPPLPPPPPPAM-PSPPPPPPPAAAPLAAPPEEPA 1531

Query: 294  LPVSTVIAAPGSAP 307
             P       P + P
Sbjct: 1532 APSPEDPELPDTRP 1545



 Score = 33.1 bits (74), Expect = 0.61
 Identities = 39/162 (24%), Positives = 55/162 (33%), Gaps = 31/162 (19%)

Query: 170 TLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDY---------------- 213
           +LS  +PP   P +  +S    L        L+P + PTVP+                  
Sbjct: 167 SLSLQDPPFSPPANGLLSPHDVLH-------LKPSQAPTVPSSLGFERLAGGGVLGPAGL 219

Query: 214 ---MTSPARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPT 270
               T P R G    P     L  +    + SS  + + E S         A P P PP 
Sbjct: 220 GPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPE 279

Query: 271 IG-PENISV----PPPSGAPPAPPLAPLLPVSTVIAAPGSAP 307
              P   +V      P+ A P PP  P   +   ++  GS P
Sbjct: 280 RALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYP 321



 Score = 32.7 bits (73), Expect = 0.80
 Identities = 15/36 (41%), Positives = 17/36 (47%), Gaps = 1/36 (2%)

Query: 366  PPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPP 401
            PP +P      PL G +       A  P PPPPPPP
Sbjct: 1015 PPELPSTVNAEPL-GLIQSGPHQAAPPPPPPPPPPP 1049



 Score = 32.0 bits (71), Expect = 1.4
 Identities = 41/177 (23%), Positives = 57/177 (32%), Gaps = 45/177 (25%)

Query: 258  GIPIAVPTPSPPTIGPENISVPPPSGAPP---------------APPLAPLLPVSTVIAA 302
            G P   P   P T GP + S P      P                  L PL P+   ++ 
Sbjct: 1172 GRPRIRPLEVPTTAGPASASTPTDGAKKPRGRGRGRGRKAEEAGGTRLEPLKPLKIKLSV 1231

Query: 303  PGSAPGSQYGTMTRQI---SRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGG------- 352
            P +  G   GT +      + HNS  SS +    +    +      QP +  G       
Sbjct: 1232 PKAGEG--LGTSSGDAISGTDHNSLDSSLTR--EKIEAKIKEVEEKQPEMKSGFMASFLD 1287

Query: 353  ---------PLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPP 400
                     PLY      + PP  P   + P +P  G    +Q     +P  P PPP
Sbjct: 1288 FLKSGKRHPPLY---QAGLTPPLSPPKSVPPSVPARG----LQPQPPATPAVPHPPP 1337



 Score = 31.2 bits (69), Expect = 2.3
 Identities = 46/177 (25%), Positives = 54/177 (30%), Gaps = 39/177 (22%)

Query: 264  PTPSPPTIGPENISVPPPSGAPPAPP----LAPLLPVSTVIAAPGSAPGSQYGTMTRQIS 319
            P P    +GP N     P+GA  +P      AP     T I  P S        + +   
Sbjct: 892  PAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDS--------LLQDEE 943

Query: 320  RHNSTTSSTSSGGYRRTPSVTA---QFSAQPHVNGGPL-----------YSQNSISIAPP 365
            R    T     GG        A   +    P    GP            Y     S A P
Sbjct: 944  RSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGP 1003

Query: 366  PPPM----PQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPP 418
              P     P   P++P T   A     I   P    PPPP         PPPPPP P
Sbjct: 1004 ETPGLGLDPNKPPELPST-VNAEPLGLIQSGPHQAAPPPPP--------PPPPPPAP 1051



 Score = 30.8 bits (68), Expect = 3.0
 Identities = 53/212 (25%), Positives = 74/212 (34%), Gaps = 49/212 (23%)

Query: 222 SQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENISVPPP 281
           + H P   + L      H+GS+G   S  N  S+   +    P P P      + S    
Sbjct: 61  TNHHPAGLSGLFDTGLHHAGSAGPDASVMNLISA---LESRGPQPGP------SASSLLS 111

Query: 282 SGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTA 341
               P+   A   P  T +   G+ PGS             ST  S+S+    + P   A
Sbjct: 112 QFRSPSWQTAMHTPGPTELFISGALPGS-------------STFPSSSALSAYQHP---A 155

Query: 342 QFSAQPHVNGGPLYSQNSISIAPPPPPM-------------PQLTPQIPLT-GFVARVQE 387
            F ++P     P+ S  S+   P  PP              P   P +P + GF     E
Sbjct: 156 SFGSRPF----PVPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQAPTVPSSLGF-----E 206

Query: 388 NIADSPTPPPPP-PPDDIPMFDDSPPPPPPPP 418
            +A      P    P   P +   PP PPPPP
Sbjct: 207 RLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPP 238



 Score = 30.4 bits (67), Expect = 4.0
 Identities = 17/46 (36%), Positives = 21/46 (45%), Gaps = 1/46 (2%)

Query: 176  PPTQKPPSPPMSGRGT-LGRNTPYKTLEPVKPPTVPNDYMTSPARL 220
            PP   P  P   GR +  G  TP   L+P KPP +P+     P  L
Sbjct: 984  PPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGL 1029


>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
           sapiens]
          Length = 1560

 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 73/264 (27%), Positives = 88/264 (33%), Gaps = 57/264 (21%)

Query: 176 PPTQKP-PSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQ 234
           PP Q P P+ P++    LG   P     P   P +P           S  S    A L  
Sbjct: 728 PPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGD 787

Query: 235 RPRTHSGSSGGSGSRENSGSSSIGIPIAVPT--PSPPTIGP----------ENISVPPPS 282
            P   S       SR  S   S+  P + P   P PP   P            + VPPP+
Sbjct: 788 SPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPA 847

Query: 283 GAP----PAPPLAPLLPVST-----VIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGY 333
             P    P PP  PL P S      +  AP   P S    +        +++S TSS   
Sbjct: 848 SNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAV--------ASSSETSSRLP 899

Query: 334 RRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSP 393
             TPS    F  Q   + GP  S       P PPP   L P+                 P
Sbjct: 900 APTPS---DFQLQFPPSQGPHKS-------PTPPPTLHLVPE-----------------P 932

Query: 394 TPPPPPPPDDIPMFDDSPPPPPPP 417
             PPPPPP    M     P  P P
Sbjct: 933 AAPPPPPPRTFQMVTTPFPALPQP 956



 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 57/175 (32%), Positives = 77/175 (44%), Gaps = 31/175 (17%)

Query: 252  SGSSSIGIPIAVPTPSP--PTIGPENISVPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGS 309
            S S S+G+PIA  +     P  GP + S P  S  PP     P LP   VI   G A GS
Sbjct: 1203 SSSRSLGLPIAASSEGHRLPGHGPLSSSAPGASTQPP-----PHLPTKLVIRH-GGAGGS 1256

Query: 310  QYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPM 369
               T  R  S  +S++SS+S+       S+ A          GP+ S+N      PP   
Sbjct: 1257 PSVTWARASSSLSSSSSSSSAAS-----SLDAD-------EDGPMPSRNR-----PPIKT 1299

Query: 370  PQLTPQIPLT------GFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPP 418
             +   +I L         +++V  N A  P   PPPPP  + + +  P PPPPPP
Sbjct: 1300 YEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPPPPPATLKVAEPPPRPPPPPP 1354



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 82/317 (25%), Positives = 109/317 (34%), Gaps = 50/317 (15%)

Query: 140 PIDYTVLDDVG---HGVKWLKAKHGNNQPAR----TGTLSRTNPPTQKPPSPP-MSGRGT 191
           P   TVL  V      V  L    G  QPA     TG  +        P +PP +S    
Sbjct: 577 PAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLP 636

Query: 192 LGRNTPYKTLEPVKPPTVPNDYMTSPARLGS-QHSPGRTAS-----LNQRPRTHSGSSGG 245
           LG   P    +  +PP  P     +P +  + Q SPG  +S     L Q P      S  
Sbjct: 637 LGLQQP----QAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPP------SAT 686

Query: 246 SGSRENSGSSSIGIPIAVPTPSPPTIGPENISVPPP---SGAPPAPPLAPLLPVSTVIAA 302
             +     S  + +P           GP ++SVP     S  PPA   AP  PV+     
Sbjct: 687 PTAILTQDSLQMFLPQERSQQPLSAEGP-HLSVPASVIVSAPPPAQDPAPATPVAKGAGL 745

Query: 303 PGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSV--TAQFSAQPHV--------NGG 352
              AP SQ        +      +     G   +PS+   A     PH+           
Sbjct: 746 GPQAPDSQASPAP---APQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSR 802

Query: 353 PLYSQNSISIAPPPPPM-----PQLTPQIPLTGFVARVQENI---ADSPTPPPPPPPDDI 404
           P     S+S  P  PP+     PQ  P +P   FV + Q  +   A +P P  P PP   
Sbjct: 803 PPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGI-FVIQNQLGVPPPASNPAPTAPGPPQPP 861

Query: 405 PMFDDSPPPPPPPPVDY 421
                 PP  P PP  +
Sbjct: 862 LRPQSQPPEGPLPPAPH 878


>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
          Length = 1263

 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 60/202 (29%), Positives = 74/202 (36%), Gaps = 41/202 (20%)

Query: 259 IPIAVPT-PSPPTIGPENISVPPPSG---------APPAPPLAPLLPVSTVIAAPGSAPG 308
           +P   P  P+PP  G     +PPP            PP PP  P LP    I++P S PG
Sbjct: 567 VPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPG 626

Query: 309 SQYGTMTRQISRHNS--TTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPP 366
               +    +S   +         G    +PS     +A P     P     S  I PPP
Sbjct: 627 GTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIP----PPPPLPGSARIPPPP 682

Query: 367 PPMPQLT----PQIPLTGFVARVQENIADSPTPPPP-------PPPDDIPMFDDSPPP-- 413
           PP+P       P  PL G         A  P PPPP       PPP   P     PPP  
Sbjct: 683 PPLPGSAGIPPPPPPLPG--------EAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPP 734

Query: 414 ----PPPPPVDYEDEEAAVVQY 431
               PPPPP  +    A V+ +
Sbjct: 735 GMGMPPPPPFGFGVPAAPVLPF 756



 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 55/173 (31%), Positives = 67/173 (38%), Gaps = 51/173 (29%)

Query: 276 ISVPP--PSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGY 333
           I+VPP  PS AP  PP  PL   S  I  P  APG             +STT        
Sbjct: 561 ITVPPSVPSRAP-VPPAPPLPGDSGTIIPPPPAPG-------------DSTTPPPPPPPP 606

Query: 334 RRTPSVTAQ--FSAQPHVNGGPLYSQ----NSISIAPPPPPMPQ---------------L 372
              P +      S+ P + GG   S     +  +  PPPPP+P+               +
Sbjct: 607 PPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAI 666

Query: 373 TPQIPLTGFVARVQENIADSPTPPP-------PPPPDDIPMFDDSPPPPPPPP 418
            P  PL G  AR+       P PPP       PPPP  +P     PPPPPP P
Sbjct: 667 PPPPPLPG-SARI------PPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLP 712



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 30/106 (28%), Positives = 40/106 (37%), Gaps = 35/106 (33%)

Query: 314 MTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLT 373
           +T+++       +S S+      PSV ++    P     PL   +   I PPP P     
Sbjct: 542 LTKELEDAKKEMASLSAAAITVPPSVPSRAPVPP---APPLPGDSGTIIPPPPAP----- 593

Query: 374 PQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPPV 419
                            DS TPPPPPPP           PPPPPP+
Sbjct: 594 ----------------GDSTTPPPPPPP-----------PPPPPPL 612



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 30/90 (33%), Positives = 37/90 (41%), Gaps = 15/90 (16%)

Query: 356 SQNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTP-PPPPPPDDIPMFDDSPPPP 414
           S  +I++ P  P    + P  PL G          DS T  PPPP P D      +PPPP
Sbjct: 557 SAAAITVPPSVPSRAPVPPAPPLPG----------DSGTIIPPPPAPGD----STTPPPP 602

Query: 415 PPPPVDYEDEEAAVVQYNDPYADGDPAWAP 444
           PPPP         V   + P   G  A +P
Sbjct: 603 PPPPPPPPPLPGGVCISSPPSLPGGTAISP 632



 Score = 38.1 bits (87), Expect = 0.019
 Identities = 41/151 (27%), Positives = 52/151 (34%), Gaps = 23/151 (15%)

Query: 165 PARTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQH 224
           PA   + +   PP   PP PP+ G   +             PP++P     SP    S  
Sbjct: 591 PAPGDSTTPPPPPPPPPPPPPLPGGVCIS-----------SPPSLPGGTAISPPPPLS-- 637

Query: 225 SPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIP-----IAVPTPSPPTIGPENISVP 279
                A++   P    G    S S    G++    P       +P P PP  G   I  P
Sbjct: 638 ---GDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPP 694

Query: 280 PP--SGAPPAPPLAPLLPVSTVIAAPGSAPG 308
           PP   G    PP  P LP    I  P   PG
Sbjct: 695 PPPLPGEAGMPPPPPPLPGGPGIPPPPPFPG 725



 Score = 33.9 bits (76), Expect = 0.36
 Identities = 45/161 (27%), Positives = 54/161 (33%), Gaps = 45/161 (27%)

Query: 165 PARTGTLSRTNPP-----TQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPAR 219
           P   G +  ++PP     T   P PP+SG  T+          P  PP      + SP+ 
Sbjct: 610 PPLPGGVCISSPPSLPGGTAISPPPPLSGDATI----------PPPPPLPEGVGIPSPSS 659

Query: 220 LGSQHSPGRTASLNQRPRTHSG----------SSGGSGSRENSGSSSIGIPIAVPT---- 265
           L     PG TA     P   S            S G            G+P   P     
Sbjct: 660 L-----PGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGG 714

Query: 266 ----PSPPTIGPENISVPPPS-GAPPAPPL------APLLP 295
               P PP  G   I  PPP  G PP PP       AP+LP
Sbjct: 715 PGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLP 755


>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
          Length = 1272

 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 60/202 (29%), Positives = 74/202 (36%), Gaps = 41/202 (20%)

Query: 259 IPIAVPT-PSPPTIGPENISVPPPSG---------APPAPPLAPLLPVSTVIAAPGSAPG 308
           +P   P  P+PP  G     +PPP            PP PP  P LP    I++P S PG
Sbjct: 576 VPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPG 635

Query: 309 SQYGTMTRQISRHNS--TTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPP 366
               +    +S   +         G    +PS     +A P     P     S  I PPP
Sbjct: 636 GTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIP----PPPPLPGSARIPPPP 691

Query: 367 PPMPQLT----PQIPLTGFVARVQENIADSPTPPPP-------PPPDDIPMFDDSPPP-- 413
           PP+P       P  PL G         A  P PPPP       PPP   P     PPP  
Sbjct: 692 PPLPGSAGIPPPPPPLPG--------EAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPP 743

Query: 414 ----PPPPPVDYEDEEAAVVQY 431
               PPPPP  +    A V+ +
Sbjct: 744 GMGMPPPPPFGFGVPAAPVLPF 765



 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 55/173 (31%), Positives = 67/173 (38%), Gaps = 51/173 (29%)

Query: 276 ISVPP--PSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGY 333
           I+VPP  PS AP  PP  PL   S  I  P  APG             +STT        
Sbjct: 570 ITVPPSVPSRAP-VPPAPPLPGDSGTIIPPPPAPG-------------DSTTPPPPPPPP 615

Query: 334 RRTPSVTAQ--FSAQPHVNGGPLYSQ----NSISIAPPPPPMPQ---------------L 372
              P +      S+ P + GG   S     +  +  PPPPP+P+               +
Sbjct: 616 PPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAI 675

Query: 373 TPQIPLTGFVARVQENIADSPTPPP-------PPPPDDIPMFDDSPPPPPPPP 418
            P  PL G  AR+       P PPP       PPPP  +P     PPPPPP P
Sbjct: 676 PPPPPLPG-SARI------PPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLP 721



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 30/106 (28%), Positives = 40/106 (37%), Gaps = 35/106 (33%)

Query: 314 MTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLT 373
           +T+++       +S S+      PSV ++    P     PL   +   I PPP P     
Sbjct: 551 LTKELEDAKKEMASLSAAAITVPPSVPSRAPVPP---APPLPGDSGTIIPPPPAP----- 602

Query: 374 PQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPPV 419
                            DS TPPPPPPP           PPPPPP+
Sbjct: 603 ----------------GDSTTPPPPPPP-----------PPPPPPL 621



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 30/90 (33%), Positives = 37/90 (41%), Gaps = 15/90 (16%)

Query: 356 SQNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTP-PPPPPPDDIPMFDDSPPPP 414
           S  +I++ P  P    + P  PL G          DS T  PPPP P D      +PPPP
Sbjct: 566 SAAAITVPPSVPSRAPVPPAPPLPG----------DSGTIIPPPPAPGD----STTPPPP 611

Query: 415 PPPPVDYEDEEAAVVQYNDPYADGDPAWAP 444
           PPPP         V   + P   G  A +P
Sbjct: 612 PPPPPPPPPLPGGVCISSPPSLPGGTAISP 641



 Score = 38.1 bits (87), Expect = 0.019
 Identities = 41/151 (27%), Positives = 52/151 (34%), Gaps = 23/151 (15%)

Query: 165 PARTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQH 224
           PA   + +   PP   PP PP+ G   +             PP++P     SP    S  
Sbjct: 600 PAPGDSTTPPPPPPPPPPPPPLPGGVCIS-----------SPPSLPGGTAISPPPPLS-- 646

Query: 225 SPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIP-----IAVPTPSPPTIGPENISVP 279
                A++   P    G    S S    G++    P       +P P PP  G   I  P
Sbjct: 647 ---GDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPP 703

Query: 280 PP--SGAPPAPPLAPLLPVSTVIAAPGSAPG 308
           PP   G    PP  P LP    I  P   PG
Sbjct: 704 PPPLPGEAGMPPPPPPLPGGPGIPPPPPFPG 734



 Score = 33.9 bits (76), Expect = 0.36
 Identities = 45/161 (27%), Positives = 54/161 (33%), Gaps = 45/161 (27%)

Query: 165 PARTGTLSRTNPP-----TQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPAR 219
           P   G +  ++PP     T   P PP+SG  T+          P  PP      + SP+ 
Sbjct: 619 PPLPGGVCISSPPSLPGGTAISPPPPLSGDATI----------PPPPPLPEGVGIPSPSS 668

Query: 220 LGSQHSPGRTASLNQRPRTHSG----------SSGGSGSRENSGSSSIGIPIAVPT---- 265
           L     PG TA     P   S            S G            G+P   P     
Sbjct: 669 L-----PGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGG 723

Query: 266 ----PSPPTIGPENISVPPPS-GAPPAPPL------APLLP 295
               P PP  G   I  PPP  G PP PP       AP+LP
Sbjct: 724 PGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLP 764


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 66/255 (25%), Positives = 102/255 (40%), Gaps = 41/255 (16%)

Query: 165 PARTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQH 224
           P+ +  L    PPT   P+ P S   T    TP     P+ PP+      ++P  L +  
Sbjct: 307 PSPSAALQSQAPPTL--PATPHSSSLTCQLATPL----PLAPPSP-----SAPPSLQTLP 355

Query: 225 SPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENISVPPPSGA 284
           SP  T      P + + +S GS + + + S     P++ P  +PP   P  +++PP   A
Sbjct: 356 SPPAT------PPSQATTSLGSPTLQATHSFLPSPPLS-PLATPPPQAPPALALPPLQ-A 407

Query: 285 PPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFS 344
           PP+PP +P  P+S +      AP +    + +  +  +   S      +    S     S
Sbjct: 408 PPSPPASP--PLSPLATPSPQAPNALAVHLLQ--APFSPPPSPPVQAPFSPPASPPVSPS 463

Query: 345 AQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPP-PPPDD 403
           A P     P  +   + + P PP  P ++P                 S TPPP  PPP  
Sbjct: 464 ATPPSQAPPSLAAPPLQVPPSPPASPPMSP-----------------SATPPPQAPPPLA 506

Query: 404 IPMFDDSPPPPPPPP 418
            P    + PPP  PP
Sbjct: 507 APPLQLAKPPPQAPP 521



 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 75/277 (27%), Positives = 105/277 (37%), Gaps = 44/277 (15%)

Query: 169 GTLSRTNPPTQKPPSPPMSGR----GT-LGRNTPYKTLEPVKPPTVP-------NDYMTS 216
           G    T+ PT   PSP M+ R    GT +G   P  +  P  P   P       +++ T+
Sbjct: 159 GARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTT 218

Query: 217 PARLGSQHSPGRTASLNQRPRTHSGSSGGS--GSRENSGSSSIGIPIAVPTPSPPTIGPE 274
                ++  P     L QRP + S SS  +   S   SG S+ G P A   PS P   P+
Sbjct: 219 EPSPAARRRPSAGGGL-QRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPK--PK 275

Query: 275 NI-SVPPPSGAPP----APPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTS 329
            + ++ PP   PP    AP L PL        +P +A  SQ    T   + H+S      
Sbjct: 276 GLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQ-APPTLPATPHSS------ 328

Query: 330 SGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQENI 389
                   S+T Q +    +      +  S+   P PP  P       L     +   + 
Sbjct: 329 --------SLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSF 380

Query: 390 ADSP------TPPPPPPPD-DIPMFDDSPPPPPPPPV 419
             SP      TPPP  PP   +P     P PP  PP+
Sbjct: 381 LPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPL 417



 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 66/273 (24%), Positives = 93/273 (34%), Gaps = 36/273 (13%)

Query: 163 NQPARTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTV-PNDYMTSPARLG 221
           + PAR+G  +R  P     PS P             K L+ ++PP V P     +PA   
Sbjct: 250 SSPARSGPSARGTPRAPAHPSQPKP-----------KGLQALRPPQVTPPRKDAAPALGP 298

Query: 222 SQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENISVPPP 281
              SP  T S    P     S           SSS+   +A P P    + P + S PP 
Sbjct: 299 LSSSPLATPS----PSAALQSQAPPTLPATPHSSSLTCQLATPLP----LAPPSPSAPPS 350

Query: 282 SGAPPAPPLAPLLPVSTVIAAPG---------SAPGSQYGTMTRQISRHNSTTSSTSSGG 332
               P+PP  P    +T + +P          S P S   T   Q     +     +   
Sbjct: 351 LQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPS 410

Query: 333 YRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPM-------PQLTPQIPLTGFVARV 385
              +P ++   +  P               +PPP P        P   P  P     ++ 
Sbjct: 411 PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQA 470

Query: 386 QENIADSPTPPPPPPPDDIPMFDDSPPPPPPPP 418
             ++A  P   PP PP   PM   + PPP  PP
Sbjct: 471 PPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP 503



 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 63/232 (27%), Positives = 88/232 (37%), Gaps = 27/232 (11%)

Query: 176 PPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQR 235
           PP Q PPSPP S        +P  T  P  P  +    + +P       SP   A  +  
Sbjct: 403 PPLQAPPSPPASPP-----LSPLATPSPQAPNALAVHLLQAP--FSPPPSPPVQAPFS-- 453

Query: 236 PRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENISVPPPSGAPP---APPLAP 292
           P      S  +     +  S    P+ VP PSPP   P + S  PP  APP   APPL  
Sbjct: 454 PPASPPVSPSATPPSQAPPSLAAPPLQVP-PSPPASPPMSPSATPPPQAPPPLAAPPLQL 512

Query: 293 LLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGG 352
             P       P  AP +      + +   +   S      +  + S+     A P     
Sbjct: 513 AKP-------PPQAPPALATPPLQALP--SPPASFPGQAPFSPSASLPMSPLATPPPQAP 563

Query: 353 PLYSQNSISIAPPPPPMPQL-TPQIPLT----GFVARVQENIADSPTPPPPP 399
           P+ +   + + P PP  P L  P+ P T      V+  +  +A +P PPPPP
Sbjct: 564 PVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPP 615



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 80/310 (25%), Positives = 106/310 (34%), Gaps = 66/310 (21%)

Query: 167 RTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSP 226
           R G +     P   P + P    GT  RN   +     +    P    TSP   G   SP
Sbjct: 61  RAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSP---GPVSSP 117

Query: 227 GRTASLNQRP-----------------------------------RTHSGSSGGSGS--- 248
           GR AS   RP                                   R  SG + G+ S   
Sbjct: 118 GR-ASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAM 176

Query: 249 --RENSGSSSIGIPIAVPT--PSPPTIGPENI-------SVPPPSGAPPAPPLA------ 291
             R  +  + +G+P   P+  P PPT GP          S   PS A    P A      
Sbjct: 177 ARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQR 236

Query: 292 PLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYR--RTPSVT-AQFSAQPH 348
           P     +  A P S+P ++ G   R   R  +  S     G +  R P VT  +  A P 
Sbjct: 237 PASRSLSSSATPLSSP-ARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPA 295

Query: 349 VNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFD 408
           +  GPL S    + +P      Q  P +P T   + +   +A +P P  PP P   P   
Sbjct: 296 L--GPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLA-TPLPLAPPSPSAPPSLQ 352

Query: 409 DSPPPPPPPP 418
             P PP  PP
Sbjct: 353 TLPSPPATPP 362



 Score = 29.3 bits (64), Expect = 8.8
 Identities = 44/188 (23%), Positives = 63/188 (33%), Gaps = 34/188 (18%)

Query: 267 SPPTIGPENISVPPPSGAPPAPPLAP-LLPVSTVIAAPGSAP------GSQYGTMTRQIS 319
           +P    P  ++  PP    P PP+ P  L V     A G  P      G    T+     
Sbjct: 16  TPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAP 75

Query: 320 RHNSTTSS-TSSGGYRRTPSVTAQFSAQP---HVNGGPLYSQNSISIAPPPPPMPQLTPQ 375
           R   T S+ TSS      P  + +    P   + + GP+ S    S    P P+ Q   +
Sbjct: 76  RAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLR 135

Query: 376 IPLTGFVARVQENIA--------------DSPTPPPPPPP---------DDIPMFDDSPP 412
           I     VAR +   A                PTP  P P           ++ +   +P 
Sbjct: 136 ISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPS 195

Query: 413 PPPPPPVD 420
             P PP +
Sbjct: 196 ARPRPPTE 203


>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
          Length = 638

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 43/140 (30%), Positives = 53/140 (37%), Gaps = 17/140 (12%)

Query: 268 PPTIGPENISVPPPSGAPPAPPLAPLLP-VSTVIAAPGSAPGSQYGTMTRQISRHNSTTS 326
           PP +G      PPPSG PP PP  PL P        P   P S     +  +    +TT+
Sbjct: 472 PPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTT 531

Query: 327 STSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQ 386
           +T+S G    P    Q +A     G P    N   +  PP   P L P            
Sbjct: 532 TTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPP------------ 579

Query: 387 ENIADSPTPPPPPPPDDIPM 406
                +P PPPPPPP    M
Sbjct: 580 ----GAPPPPPPPPPGSAGM 595



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 45/160 (28%), Positives = 63/160 (39%), Gaps = 23/160 (14%)

Query: 140 PID-YTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPY 198
           P+D Y     VG GV  L    G   P   G +    PP    P PP S     G   P+
Sbjct: 446 PMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPS-----GPLPPW 500

Query: 199 KTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHSGSSGGSGS------RENS 252
           +  +   PP  P     S +   S   P       Q+  T + +S G+GS      ++ +
Sbjct: 501 QQQQQQPPPPPP----PSSSMASSTPLPW------QQNTTTTTTSAGTGSIPPWQQQQAA 550

Query: 253 GSSSIGIPIAVPTPSPPTIGPENISVPPPSGAPPAPPLAP 292
            ++S G P     P+   + P  +  P P GAPP PP  P
Sbjct: 551 AAASPGAPQMQGNPTMVPL-PPGVQPPLPPGAPPPPPPPP 589



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 51/216 (23%), Positives = 69/216 (31%), Gaps = 38/216 (17%)

Query: 212 DYMTSPARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTI 271
           +Y++  A LG    P    S +    T   S+    +  N+             P PP++
Sbjct: 312 EYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANN-------------PPPPSL 358

Query: 272 GPENISVPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSG 331
                S PP   + P+               PG  P S    +      H       +  
Sbjct: 359 MSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPN 418

Query: 332 GYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPP----PPPMPQLTPQIPLTGFVARVQE 387
           G    P         P +N GP          PP    PPPM Q     P+   V R+ +
Sbjct: 419 G----PPPPWMQPPPPPMNQGP---------HPPGHHGPPPMDQYLGSTPVGSGVYRLHQ 465

Query: 388 NIADSPTPP----PPPPPDDIPMFDDSPPPPPPPPV 419
                P PP    PPPPP         PPPPP  P+
Sbjct: 466 GKGMMPPPPMGMMPPPPPPP----SGQPPPPPSGPL 497



 Score = 31.2 bits (69), Expect = 2.3
 Identities = 21/61 (34%), Positives = 27/61 (44%), Gaps = 16/61 (26%)

Query: 366 PPPMPQLTPQIPLTGFVARVQENIADSPTPP---PPPPPDDIPMFDDSPPPPP---PPPV 419
           P P+P LT      G      ++  + P PP   PPPPP      +  P PP    PPP+
Sbjct: 398 PHPLPSLTG-----GHGGHPMQHNPNGPPPPWMQPPPPP-----MNQGPHPPGHHGPPPM 447

Query: 420 D 420
           D
Sbjct: 448 D 448


>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
          Length = 1220

 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 26/52 (50%), Positives = 35/52 (67%)

Query: 450  KVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVE 501
            +V+ +YDYT   DDEL+F +G II V+ K D  W++G  N   GLFP NYV+
Sbjct: 1159 QVIGMYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGEVNGQVGLFPSNYVK 1210



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 23/61 (37%), Positives = 34/61 (55%), Gaps = 1/61 (1%)

Query: 440  PAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNY 499
            PA  P    E+ +A+Y Y   +  +L+F +G +I V KK+ D W+ G      G+FP NY
Sbjct: 996  PAAKPVVSGEEFIAMYTYESSEQGDLTFQQGDVILVTKKDGD-WWTGTVGDKAGVFPSNY 1054

Query: 500  V 500
            V
Sbjct: 1055 V 1055



 Score = 38.9 bits (89), Expect = 0.011
 Identities = 23/62 (37%), Positives = 32/62 (51%), Gaps = 7/62 (11%)

Query: 445  KNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVC-----NRVTGLFPGNY 499
            K  I +V+A   YT    ++L+   G +I + KKN  GW+EG        R  G FP NY
Sbjct: 1075 KPEIAQVIA--SYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANY 1132

Query: 500  VE 501
            V+
Sbjct: 1133 VK 1134



 Score = 33.9 bits (76), Expect = 0.36
 Identities = 18/58 (31%), Positives = 25/58 (43%), Gaps = 7/58 (12%)

Query: 453 AIYDYTKDKDDELSFMEGAIIYV-------IKKNDDGWYEGVCNRVTGLFPGNYVESI 503
           A+Y +     DE++   G I+ V        +  + GW  G     TG FP NY E I
Sbjct: 747 ALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGELKGKTGWFPANYAEKI 804



 Score = 33.5 bits (75), Expect = 0.47
 Identities = 17/51 (33%), Positives = 29/51 (56%), Gaps = 1/51 (1%)

Query: 453 AIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESI 503
           A+Y +   KD+ L+F +  +I V+++ D  W+ G      G FP +YV+ I
Sbjct: 920 ALYPWRAKKDNHLNFNKNDVITVLEQQDMWWF-GEVQGQKGWFPKSYVKLI 969


>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
          Length = 1721

 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 26/52 (50%), Positives = 35/52 (67%)

Query: 450  KVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVE 501
            +V+ +YDYT   DDEL+F +G II V+ K D  W++G  N   GLFP NYV+
Sbjct: 1159 QVIGMYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGEVNGQVGLFPSNYVK 1210



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 23/61 (37%), Positives = 34/61 (55%), Gaps = 1/61 (1%)

Query: 440  PAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNY 499
            PA  P    E+ +A+Y Y   +  +L+F +G +I V KK+ D W+ G      G+FP NY
Sbjct: 996  PAAKPVVSGEEFIAMYTYESSEQGDLTFQQGDVILVTKKDGD-WWTGTVGDKAGVFPSNY 1054

Query: 500  V 500
            V
Sbjct: 1055 V 1055



 Score = 38.9 bits (89), Expect = 0.011
 Identities = 23/62 (37%), Positives = 32/62 (51%), Gaps = 7/62 (11%)

Query: 445  KNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVC-----NRVTGLFPGNY 499
            K  I +V+A   YT    ++L+   G +I + KKN  GW+EG        R  G FP NY
Sbjct: 1075 KPEIAQVIA--SYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANY 1132

Query: 500  VE 501
            V+
Sbjct: 1133 VK 1134



 Score = 33.9 bits (76), Expect = 0.36
 Identities = 18/58 (31%), Positives = 25/58 (43%), Gaps = 7/58 (12%)

Query: 453 AIYDYTKDKDDELSFMEGAIIYV-------IKKNDDGWYEGVCNRVTGLFPGNYVESI 503
           A+Y +     DE++   G I+ V        +  + GW  G     TG FP NY E I
Sbjct: 747 ALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGELKGKTGWFPANYAEKI 804



 Score = 33.5 bits (75), Expect = 0.47
 Identities = 17/51 (33%), Positives = 29/51 (56%), Gaps = 1/51 (1%)

Query: 453 AIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESI 503
           A+Y +   KD+ L+F +  +I V+++ D  W+ G      G FP +YV+ I
Sbjct: 920 ALYPWRAKKDNHLNFNKNDVITVLEQQDMWWF-GEVQGQKGWFPKSYVKLI 969


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.130    0.389 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,105,193
Number of Sequences: 37866
Number of extensions: 1912996
Number of successful extensions: 39242
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 731
Number of HSP's successfully gapped in prelim test: 1380
Number of HSP's that attempted gapping in prelim test: 13367
Number of HSP's gapped (non-prelim): 13432
length of query: 508
length of database: 18,247,518
effective HSP length: 107
effective length of query: 401
effective length of database: 14,195,856
effective search space: 5692538256
effective search space used: 5692538256
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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