Guide to the Human Genome
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Search of human proteins with 61742827

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|61742827 disrupted in schizophrenia 1 isoform Es [Homo
sapiens]
         (369 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|61742827 disrupted in schizophrenia 1 isoform Es [Homo sapiens]    766   0.0  
gi|61742829 disrupted in schizophrenia 1 isoform S [Homo sapiens]     720   0.0  
gi|61742825 disrupted in schizophrenia 1 isoform Lv [Homo sapiens]    720   0.0  
gi|61742823 disrupted in schizophrenia 1 isoform L [Homo sapiens]     720   0.0  
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f...    38   0.013
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e...    38   0.013
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d...    38   0.013
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ...    38   0.013
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ...    38   0.013
gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c ...    38   0.013
gi|160707881 formin 2 [Homo sapiens]                                   38   0.017
gi|239755824 PREDICTED: hypothetical protein [Homo sapiens]            37   0.022
gi|239750321 PREDICTED: hypothetical protein [Homo sapiens]            37   0.022
gi|239744627 PREDICTED: hypothetical protein [Homo sapiens]            37   0.022
gi|239753060 PREDICTED: similar to hCG1739112 [Homo sapiens]           36   0.063
gi|239747612 PREDICTED: hypothetical protein XP_002347909 [Homo ...    36   0.063
gi|169206489 PREDICTED: hypothetical protein [Homo sapiens]            35   0.082
gi|169205942 PREDICTED: hypothetical protein [Homo sapiens]            35   0.082
gi|12707580 paired-like homeobox 2b [Homo sapiens]                     35   0.082
gi|28559039 mediator complex subunit 1 [Homo sapiens]                  35   0.11 
gi|11138123 cholinergic receptor, nicotinic, alpha 10 [Homo sapi...    35   0.14 
gi|145699105 connexin40.1 [Homo sapiens]                               35   0.14 
gi|188536004 zinc finger protein 469 [Homo sapiens]                    34   0.24 
gi|186700623 Rab-like GTP-binding protein 1 isoform 1 [Homo sapi...    33   0.41 
gi|122692281 hypothetical protein LOC645369 [Homo sapiens]             33   0.41 
gi|38158015 mastermind-like 3 [Homo sapiens]                           33   0.41 
gi|112821681 G protein-regulated inducer of neurite outgrowth 1 ...    33   0.41 
gi|67089160 promyelocytic leukemia protein isoform 11 [Homo sapi...    33   0.53 
gi|15451765 promyelocytic leukemia protein isoform 9 [Homo sapiens]    33   0.53 
gi|45827771 autoantigen RCD8 [Homo sapiens]                            33   0.53 

>gi|61742827 disrupted in schizophrenia 1 isoform Es [Homo sapiens]
          Length = 369

 Score =  766 bits (1977), Expect = 0.0
 Identities = 369/369 (100%), Positives = 369/369 (100%)

Query: 1   MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA 60
           MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA
Sbjct: 1   MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA 60

Query: 61  VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI 120
           VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI
Sbjct: 61  VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI 120

Query: 121 QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA 180
           QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA
Sbjct: 121 QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA 180

Query: 181 ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ 240
           ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ
Sbjct: 181 ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ 240

Query: 241 SPQEMGAKAASLDGPHEDPRCLSRPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG 300
           SPQEMGAKAASLDGPHEDPRCLSRPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG
Sbjct: 241 SPQEMGAKAASLDGPHEDPRCLSRPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG 300

Query: 301 SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMELEPIALDPPWK 360
           SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMELEPIALDPPWK
Sbjct: 301 SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMELEPIALDPPWK 360

Query: 361 PRHPEPNSY 369
           PRHPEPNSY
Sbjct: 361 PRHPEPNSY 369


>gi|61742829 disrupted in schizophrenia 1 isoform S [Homo sapiens]
          Length = 678

 Score =  720 bits (1859), Expect = 0.0
 Identities = 350/355 (98%), Positives = 352/355 (99%)

Query: 1   MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA 60
           MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA
Sbjct: 1   MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA 60

Query: 61  VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI 120
           VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI
Sbjct: 61  VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI 120

Query: 121 QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA 180
           QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA
Sbjct: 121 QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA 180

Query: 181 ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ 240
           ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ
Sbjct: 181 ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ 240

Query: 241 SPQEMGAKAASLDGPHEDPRCLSRPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG 300
           SPQEMGAKAASLDGPHEDPRCLSRPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG
Sbjct: 241 SPQEMGAKAASLDGPHEDPRCLSRPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG 300

Query: 301 SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMELEPIAL 355
           SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQME+  + L
Sbjct: 301 SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRL 355


>gi|61742825 disrupted in schizophrenia 1 isoform Lv [Homo sapiens]
          Length = 832

 Score =  720 bits (1859), Expect = 0.0
 Identities = 350/355 (98%), Positives = 352/355 (99%)

Query: 1   MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA 60
           MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA
Sbjct: 1   MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA 60

Query: 61  VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI 120
           VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI
Sbjct: 61  VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI 120

Query: 121 QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA 180
           QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA
Sbjct: 121 QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA 180

Query: 181 ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ 240
           ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ
Sbjct: 181 ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ 240

Query: 241 SPQEMGAKAASLDGPHEDPRCLSRPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG 300
           SPQEMGAKAASLDGPHEDPRCLSRPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG
Sbjct: 241 SPQEMGAKAASLDGPHEDPRCLSRPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG 300

Query: 301 SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMELEPIAL 355
           SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQME+  + L
Sbjct: 301 SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRL 355


>gi|61742823 disrupted in schizophrenia 1 isoform L [Homo sapiens]
          Length = 854

 Score =  720 bits (1859), Expect = 0.0
 Identities = 350/355 (98%), Positives = 352/355 (99%)

Query: 1   MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA 60
           MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA
Sbjct: 1   MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA 60

Query: 61  VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI 120
           VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI
Sbjct: 61  VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI 120

Query: 121 QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA 180
           QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA
Sbjct: 121 QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA 180

Query: 181 ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ 240
           ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ
Sbjct: 181 ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ 240

Query: 241 SPQEMGAKAASLDGPHEDPRCLSRPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG 300
           SPQEMGAKAASLDGPHEDPRCLSRPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG
Sbjct: 241 SPQEMGAKAASLDGPHEDPRCLSRPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG 300

Query: 301 SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMELEPIAL 355
           SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQME+  + L
Sbjct: 301 SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRL 355


>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
           [Homo sapiens]
          Length = 1412

 Score = 38.1 bits (87), Expect = 0.013
 Identities = 36/138 (26%), Positives = 51/138 (36%), Gaps = 15/138 (10%)

Query: 72  SGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGIQLRGGTRLPDR 131
           S EES   E    Q     +     +P  ++A+AP   S R          +G    P R
Sbjct: 336 SSEESDSEEEAPAQAKPSGK-----APQVRAASAPAKESPR----------KGAAPAPPR 380

Query: 132 LSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSAELSSNSCSPGC 191
            + P        +QE  +  SSE  D+  EA  +  A +V+  G  P  + +S       
Sbjct: 381 KTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPL 440

Query: 192 GPEVPPTPPGSHSAFTSS 209
           G    P PPG     T S
Sbjct: 441 GKGAGPVPPGKVGPATPS 458


>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
           [Homo sapiens]
          Length = 1451

 Score = 38.1 bits (87), Expect = 0.013
 Identities = 36/138 (26%), Positives = 51/138 (36%), Gaps = 15/138 (10%)

Query: 72  SGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGIQLRGGTRLPDR 131
           S EES   E    Q     +     +P  ++A+AP   S R          +G    P R
Sbjct: 413 SSEESDSEEEAPAQAKPSGK-----APQVRAASAPAKESPR----------KGAAPAPPR 457

Query: 132 LSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSAELSSNSCSPGC 191
            + P        +QE  +  SSE  D+  EA  +  A +V+  G  P  + +S       
Sbjct: 458 KTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPL 517

Query: 192 GPEVPPTPPGSHSAFTSS 209
           G    P PPG     T S
Sbjct: 518 GKGAGPVPPGKVGPATPS 535



 Score = 30.0 bits (66), Expect = 3.5
 Identities = 38/182 (20%), Positives = 68/182 (37%), Gaps = 5/182 (2%)

Query: 80  ESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHF-GIQLRGGTRLPD-RLSWPCG 137
           ES + + G +S         S+  A+  +  VR  SA   G   +G T  P  +      
Sbjct: 269 ESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVAS 328

Query: 138 PGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSAELSSNSCSPGCGPEVPP 197
              AG  +E +   S E+ D+  E   +    + +A+G       +S            P
Sbjct: 329 QTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAP 388

Query: 198 TPPGSHSAFTSSFSFIRL--SLGSAGERGEAEGCPPSREAESHCQSPQEMGAKAASLDGP 255
            PPG      +     +      S+ E  ++E   P+ +A+   ++PQ   A A + + P
Sbjct: 389 APPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPA-QAKPSGKAPQVRAASAPAKESP 447

Query: 256 HE 257
            +
Sbjct: 448 RK 449


>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
           [Homo sapiens]
          Length = 1488

 Score = 38.1 bits (87), Expect = 0.013
 Identities = 36/138 (26%), Positives = 51/138 (36%), Gaps = 15/138 (10%)

Query: 72  SGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGIQLRGGTRLPDR 131
           S EES   E    Q     +     +P  ++A+AP   S R          +G    P R
Sbjct: 413 SSEESDSEEEAPAQAKPSGK-----APQVRAASAPAKESPR----------KGAAPAPPR 457

Query: 132 LSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSAELSSNSCSPGC 191
            + P        +QE  +  SSE  D+  EA  +  A +V+  G  P  + +S       
Sbjct: 458 KTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPL 517

Query: 192 GPEVPPTPPGSHSAFTSS 209
           G    P PPG     T S
Sbjct: 518 GKGAGPVPPGKVGPATPS 535



 Score = 30.0 bits (66), Expect = 3.5
 Identities = 38/182 (20%), Positives = 68/182 (37%), Gaps = 5/182 (2%)

Query: 80  ESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHF-GIQLRGGTRLPD-RLSWPCG 137
           ES + + G +S         S+  A+  +  VR  SA   G   +G T  P  +      
Sbjct: 269 ESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVAS 328

Query: 138 PGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSAELSSNSCSPGCGPEVPP 197
              AG  +E +   S E+ D+  E   +    + +A+G       +S            P
Sbjct: 329 QTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAP 388

Query: 198 TPPGSHSAFTSSFSFIRL--SLGSAGERGEAEGCPPSREAESHCQSPQEMGAKAASLDGP 255
            PPG      +     +      S+ E  ++E   P+ +A+   ++PQ   A A + + P
Sbjct: 389 APPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPA-QAKPSGKAPQVRAASAPAKESP 447

Query: 256 HE 257
            +
Sbjct: 448 RK 449


>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b
           [Homo sapiens]
          Length = 1411

 Score = 38.1 bits (87), Expect = 0.013
 Identities = 36/138 (26%), Positives = 51/138 (36%), Gaps = 15/138 (10%)

Query: 72  SGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGIQLRGGTRLPDR 131
           S EES   E    Q     +     +P  ++A+AP   S R          +G    P R
Sbjct: 336 SSEESDSEEEAPAQAKPSGK-----APQVRAASAPAKESPR----------KGAAPAPPR 380

Query: 132 LSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSAELSSNSCSPGC 191
            + P        +QE  +  SSE  D+  EA  +  A +V+  G  P  + +S       
Sbjct: 381 KTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPL 440

Query: 192 GPEVPPTPPGSHSAFTSS 209
           G    P PPG     T S
Sbjct: 441 GKGAGPVPPGKVGPATPS 458


>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a
           [Homo sapiens]
          Length = 1450

 Score = 38.1 bits (87), Expect = 0.013
 Identities = 36/138 (26%), Positives = 51/138 (36%), Gaps = 15/138 (10%)

Query: 72  SGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGIQLRGGTRLPDR 131
           S EES   E    Q     +     +P  ++A+AP   S R          +G    P R
Sbjct: 413 SSEESDSEEEAPAQAKPSGK-----APQVRAASAPAKESPR----------KGAAPAPPR 457

Query: 132 LSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSAELSSNSCSPGC 191
            + P        +QE  +  SSE  D+  EA  +  A +V+  G  P  + +S       
Sbjct: 458 KTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPL 517

Query: 192 GPEVPPTPPGSHSAFTSS 209
           G    P PPG     T S
Sbjct: 518 GKGAGPVPPGKVGPATPS 535



 Score = 30.0 bits (66), Expect = 3.5
 Identities = 38/182 (20%), Positives = 68/182 (37%), Gaps = 5/182 (2%)

Query: 80  ESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHF-GIQLRGGTRLPD-RLSWPCG 137
           ES + + G +S         S+  A+  +  VR  SA   G   +G T  P  +      
Sbjct: 269 ESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVAS 328

Query: 138 PGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSAELSSNSCSPGCGPEVPP 197
              AG  +E +   S E+ D+  E   +    + +A+G       +S            P
Sbjct: 329 QTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAP 388

Query: 198 TPPGSHSAFTSSFSFIRL--SLGSAGERGEAEGCPPSREAESHCQSPQEMGAKAASLDGP 255
            PPG      +     +      S+ E  ++E   P+ +A+   ++PQ   A A + + P
Sbjct: 389 APPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPA-QAKPSGKAPQVRAASAPAKESP 447

Query: 256 HE 257
            +
Sbjct: 448 RK 449


>gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c
           [Homo sapiens]
          Length = 958

 Score = 38.1 bits (87), Expect = 0.013
 Identities = 36/138 (26%), Positives = 51/138 (36%), Gaps = 15/138 (10%)

Query: 72  SGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGIQLRGGTRLPDR 131
           S EES   E    Q     +     +P  ++A+AP   S R          +G    P R
Sbjct: 413 SSEESDSEEEAPAQAKPSGK-----APQVRAASAPAKESPR----------KGAAPAPPR 457

Query: 132 LSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSAELSSNSCSPGC 191
            + P        +QE  +  SSE  D+  EA  +  A +V+  G  P  + +S       
Sbjct: 458 KTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPL 517

Query: 192 GPEVPPTPPGSHSAFTSS 209
           G    P PPG     T S
Sbjct: 518 GKGAGPVPPGKVGPATPS 535



 Score = 30.0 bits (66), Expect = 3.5
 Identities = 38/182 (20%), Positives = 68/182 (37%), Gaps = 5/182 (2%)

Query: 80  ESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHF-GIQLRGGTRLPD-RLSWPCG 137
           ES + + G +S         S+  A+  +  VR  SA   G   +G T  P  +      
Sbjct: 269 ESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVAS 328

Query: 138 PGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSAELSSNSCSPGCGPEVPP 197
              AG  +E +   S E+ D+  E   +    + +A+G       +S            P
Sbjct: 329 QTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAP 388

Query: 198 TPPGSHSAFTSSFSFIRL--SLGSAGERGEAEGCPPSREAESHCQSPQEMGAKAASLDGP 255
            PPG      +     +      S+ E  ++E   P+ +A+   ++PQ   A A + + P
Sbjct: 389 APPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPA-QAKPSGKAPQVRAASAPAKESP 447

Query: 256 HE 257
            +
Sbjct: 448 RK 449


>gi|160707881 formin 2 [Homo sapiens]
          Length = 1722

 Score = 37.7 bits (86), Expect = 0.017
 Identities = 40/133 (30%), Positives = 52/133 (39%), Gaps = 8/133 (6%)

Query: 192 GPEVPPTPPGSHSAFTSSFSFI-RLSLGSAGERGEAEGCPPSREAESHCQSPQEMGAKAA 250
           G E P  PP + S    +F  + R  LG +G  GEA G P + +A S      E  + AA
Sbjct: 228 GAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPE--SLAA 285

Query: 251 SLDGPHEDPRCLSRPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPGSSSSLDPSLA 310
               P + P     P S      S   AQ A   S P       P+  PG  ++  P + 
Sbjct: 286 EPREPQQPPSPGGLPVS---EAPSLPAAQPAAKDS-PSSTAFPFPEAGPGEEAAGAP-VR 340

Query: 311 GCGGDGSSGSGDA 323
           G G     G  DA
Sbjct: 341 GAGDTDEEGEEDA 353



 Score = 32.3 bits (72), Expect = 0.70
 Identities = 50/195 (25%), Positives = 68/195 (34%), Gaps = 28/195 (14%)

Query: 138 PGSAGWQQEFAAM-DSSETLDASW---EAACSDGARRVRAAGSLPSAELSSNSCSPGCGP 193
           PGS   +Q  +A+ D  E+L A     +   S G   V  A SLP+A+ ++         
Sbjct: 264 PGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAF 323

Query: 194 EVPPTPPGSHSAFT------------SSFSFIRLSLGSAGER-----GEAEGCPPSREAE 236
             P   PG  +A                 +F     GS GE      GE        E E
Sbjct: 324 PFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPE 383

Query: 237 SHCQSPQEMGAKAASLDG-PHEDPRCLSRPFSLLATRVSADLAQAARNSSRPERDMHSLP 295
              Q P      AASL G P    RC  +P+ L+       +    R  S P       P
Sbjct: 384 EEAQGPD--APAAASLPGSPAPSQRCF-KPYPLI---TPCYIKTTTRQLSSPNHSPSQSP 437

Query: 296 DMDPGSSSSLDPSLA 310
           +  P      +PSL+
Sbjct: 438 NQSPRIKRRPEPSLS 452



 Score = 30.8 bits (68), Expect = 2.0
 Identities = 20/72 (27%), Positives = 28/72 (38%), Gaps = 2/72 (2%)

Query: 129 PDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSAELSSNSCS 188
           P  L W  G G  G Q   +     +T      ++    +  + +   LP  E  S+S  
Sbjct: 813 PPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTE--SSSSM 870

Query: 189 PGCGPEVPPTPP 200
           PG G   PP PP
Sbjct: 871 PGLGMVPPPPPP 882


>gi|239755824 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 194

 Score = 37.4 bits (85), Expect = 0.022
 Identities = 35/121 (28%), Positives = 47/121 (38%), Gaps = 14/121 (11%)

Query: 2   PGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPAV 61
           PGG   G  AA   GG  H  G      P+AC    R A RPG +        G L  A 
Sbjct: 63  PGGQAPGPHAAPEAGGAGH--GDPGTRAPSACIDAGRAADRPGAV-------AGRLDRAQ 113

Query: 62  GTLFRFPGGVSGEE-----SHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSA 116
           G +    GG SGE           ++A +  + +        +S+S A P   S  G+ +
Sbjct: 114 GPVVGGEGGASGEAHAVRGERKDRTQALRTTVAACASRATRVISQSEAPPPPRSRFGSRS 173

Query: 117 H 117
           H
Sbjct: 174 H 174


>gi|239750321 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 194

 Score = 37.4 bits (85), Expect = 0.022
 Identities = 35/121 (28%), Positives = 47/121 (38%), Gaps = 14/121 (11%)

Query: 2   PGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPAV 61
           PGG   G  AA   GG  H  G      P+AC    R A RPG +        G L  A 
Sbjct: 63  PGGQAPGPHAAPEAGGAGH--GDPGTRAPSACIDAGRAADRPGAV-------AGRLDRAQ 113

Query: 62  GTLFRFPGGVSGEE-----SHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSA 116
           G +    GG SGE           ++A +  + +        +S+S A P   S  G+ +
Sbjct: 114 GPVVGGEGGASGEAHAVRGERKDRTQALRTTVAACASRATRVISQSEAPPPPRSRFGSRS 173

Query: 117 H 117
           H
Sbjct: 174 H 174


>gi|239744627 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 194

 Score = 37.4 bits (85), Expect = 0.022
 Identities = 35/121 (28%), Positives = 47/121 (38%), Gaps = 14/121 (11%)

Query: 2   PGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPAV 61
           PGG   G  AA   GG  H  G      P+AC    R A RPG +        G L  A 
Sbjct: 63  PGGQAPGPHAAPEAGGAGH--GDPGTRAPSACIDAGRAADRPGAV-------AGRLDRAQ 113

Query: 62  GTLFRFPGGVSGEE-----SHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSA 116
           G +    GG SGE           ++A +  + +        +S+S A P   S  G+ +
Sbjct: 114 GPVVGGEGGASGEAHAVRGERKDRTQALRTTVAACASRATRVISQSEAPPPPRSRFGSRS 173

Query: 117 H 117
           H
Sbjct: 174 H 174


>gi|239753060 PREDICTED: similar to hCG1739112 [Homo sapiens]
          Length = 211

 Score = 35.8 bits (81), Expect = 0.063
 Identities = 32/102 (31%), Positives = 45/102 (44%), Gaps = 12/102 (11%)

Query: 170 RVRAAGSLPSAELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGC 229
           R+ AA  + S+ LS+ S  P    + P    G+HS+     +    S G +G R  +   
Sbjct: 85  RLTAASRVQSSCLSAASAGPAPACQWPLQAHGAHSSQRPFQAQFFPSGGLSGPRTSS--- 141

Query: 230 PPSREAESHCQSPQEMGAKAASLDGPHEDPRCLSRPFSLLAT 271
             SR  ++H Q P         L GP    R LSRP S L+T
Sbjct: 142 --SRPLQTHLQPP-------GVLSGPSSSSRLLSRPDSCLST 174


>gi|239747612 PREDICTED: hypothetical protein XP_002347909 [Homo
           sapiens]
          Length = 211

 Score = 35.8 bits (81), Expect = 0.063
 Identities = 32/102 (31%), Positives = 45/102 (44%), Gaps = 12/102 (11%)

Query: 170 RVRAAGSLPSAELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGC 229
           R+ AA  + S+ LS+ S  P    + P    G+HS+     +    S G +G R  +   
Sbjct: 85  RLTAASRVQSSCLSAASAGPAPACQWPLQAHGAHSSQRPFQAQFFPSGGLSGPRTSS--- 141

Query: 230 PPSREAESHCQSPQEMGAKAASLDGPHEDPRCLSRPFSLLAT 271
             SR  ++H Q P         L GP    R LSRP S L+T
Sbjct: 142 --SRPLQTHLQPP-------GVLSGPSSSSRLLSRPDSCLST 174


>gi|169206489 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 564

 Score = 35.4 bits (80), Expect = 0.082
 Identities = 64/251 (25%), Positives = 94/251 (37%), Gaps = 34/251 (13%)

Query: 4   GGPQGAPAAAGGGGVSHRAGSRDCLPPAAC--FRRRRLARRPGYMRSSTGPGIGFLSPAV 61
           G   G  A   GGG S RAG+R   P + C    R+  +RR   + SS G G G   P  
Sbjct: 158 GSHSGPRAGTPGGGRSSRAGARRKTPLSLCPLKLRKGSSRRCQGLGSSWG-GSG-TPPPP 215

Query: 62  GTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGIQ 121
             L+   GG +G  +    S  R C   +       P S   A    T  RG   H G+Q
Sbjct: 216 RALWNRHGGAAGARAQVRGSEKRACPGST------LPPSSVLAGCVGTRARG---HGGVQ 266

Query: 122 LRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSAE 181
            +       R S P    ++G +           LD S +AA +      R A + P + 
Sbjct: 267 RQ-------RFSAPSSHSTSGGRPTGERSSREPLLDPS-KAARASALPTARVAHASPPS- 317

Query: 182 LSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEG--CPPSREAESHC 239
           L++     G G   P    G+          +R  L +A E     G    P++ +E   
Sbjct: 318 LAAAQWRLGGGKRKPTVLKGA----------VRTDLSTAEEEDPRSGRALEPAQGSELWA 367

Query: 240 QSPQEMGAKAA 250
           ++ +  G+  A
Sbjct: 368 RAERHGGSSGA 378


>gi|169205942 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 564

 Score = 35.4 bits (80), Expect = 0.082
 Identities = 64/251 (25%), Positives = 94/251 (37%), Gaps = 34/251 (13%)

Query: 4   GGPQGAPAAAGGGGVSHRAGSRDCLPPAAC--FRRRRLARRPGYMRSSTGPGIGFLSPAV 61
           G   G  A   GGG S RAG+R   P + C    R+  +RR   + SS G G G   P  
Sbjct: 158 GSHSGPRAGTPGGGRSSRAGARRKTPLSLCPLKLRKGSSRRCQGLGSSWG-GSG-TPPPP 215

Query: 62  GTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGIQ 121
             L+   GG +G  +    S  R C   +       P S   A    T  RG   H G+Q
Sbjct: 216 RALWNRHGGAAGARAQVRGSEKRACPGST------LPPSSVLAGCVGTRARG---HGGVQ 266

Query: 122 LRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSAE 181
            +       R S P    ++G +           LD S +AA +      R A + P + 
Sbjct: 267 RQ-------RFSAPSSHSTSGGRPTGERSSREPLLDPS-KAARASALPTARVAHASPPS- 317

Query: 182 LSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEG--CPPSREAESHC 239
           L++     G G   P    G+          +R  L +A E     G    P++ +E   
Sbjct: 318 LAAAQWRLGGGKRKPTVLKGA----------VRTDLSTAEEEDPRSGRALEPAQGSELWA 367

Query: 240 QSPQEMGAKAA 250
           ++ +  G+  A
Sbjct: 368 RAERHGGSSGA 378


>gi|12707580 paired-like homeobox 2b [Homo sapiens]
          Length = 314

 Score = 35.4 bits (80), Expect = 0.082
 Identities = 31/100 (31%), Positives = 44/100 (44%), Gaps = 8/100 (8%)

Query: 3   GGGPQ--GAPAAAGGGGVS---HRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFL 57
           GGGP   GAP AAG GG      + G+      AA       A   G + ++ GPG G+ 
Sbjct: 215 GGGPSPAGAPGAAGPGGPGGEPGKGGAAAAAAAAAAAAAAAAAAAAGGLAAAGGPGQGW- 273

Query: 58  SPAVGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRS 97
           +P  G +   P  + G  +    S  R  G  ++  LV+S
Sbjct: 274 APGPGPITSIPDSLGGPFASVLSSLQRPNG--AKAALVKS 311


>gi|28559039 mediator complex subunit 1 [Homo sapiens]
          Length = 1581

 Score = 35.0 bits (79), Expect = 0.11
 Identities = 67/295 (22%), Positives = 101/295 (34%), Gaps = 61/295 (20%)

Query: 6    PQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYM-RSSTGPGIGFLSPAVGTL 64
            P+   A   G   SH + +R   PP +       ++ PG   RS T PG+    P     
Sbjct: 1010 PKRKKADTEGKSPSHSSSNRPFTPPTSTGG----SKSPGSAGRSQTPPGVA-TPPIPKIT 1064

Query: 65   FRFPGGV--------------------SGEESHHSESRARQCGLDSRGLLVRSPVSKSAA 104
             + P G                     SG +SHHS S +      + G +      KS+ 
Sbjct: 1065 IQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKM------KSSK 1118

Query: 105  APTVTSVRGTSAHFGIQLRGGTRLPDRLSWPCG-PGSAGWQQEFAAMDSSETLDASWEAA 163
            +   +S + +S+ +  Q   G+      S   G PGS+   +   +  SS T        
Sbjct: 1119 SEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSST------KM 1172

Query: 164  CSDGARRVRAAGSLPSAELSSNSCSPGCGPE--------VPPTPP-------------GS 202
               G        SL    +S +   P  G +        VP TPP             GS
Sbjct: 1173 KPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGS 1232

Query: 203  HSAFTSSFSFIRLSLGSAGERGEAEGCPP-SREAESHCQSPQEMGAKAASLDGPH 256
            H + TSS S ++ S G       ++  PP S    +   S    G+  +S    H
Sbjct: 1233 HMSGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQH 1287



 Score = 31.6 bits (70), Expect = 1.2
 Identities = 33/134 (24%), Positives = 55/134 (41%), Gaps = 17/134 (12%)

Query: 165  SDGARRVRAAGSLPSAELSSNSCSPGCGPEVPPTPPGSHS--AFTSSFSFIRLSLGSA-G 221
            S G+     +G+  S+ + S+S     G     TPP S+S  A +SSFS    S+ S+  
Sbjct: 1226 SSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQN 1285

Query: 222  ERGEAEGCPPSREAESHCQSPQEMGAKAASLDGP-HEDPRCLSRPFSLLATRVSADLAQA 280
            + G ++G  PSR  +    +  +         GP  EDP             +   +  +
Sbjct: 1286 QHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDP-------------LDGQMGVS 1332

Query: 281  ARNSSRPERDMHSL 294
              +SS P    H++
Sbjct: 1333 TNSSSHPMSSKHNM 1346



 Score = 29.3 bits (64), Expect = 5.9
 Identities = 36/143 (25%), Positives = 54/143 (37%), Gaps = 8/143 (5%)

Query: 183  SSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAE--GCPPSREAESHCQ 240
            SS+S S     +   +   S S  +SS    + S GS+  +  ++  G P S     H  
Sbjct: 1104 SSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGL 1163

Query: 241  SPQEMGAKAASLDGPHEDPRCLSRPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG 300
            S      K      P   P  L  P SL    +S   ++    S +    M  +P   P 
Sbjct: 1164 SSGSSSTKMK----PQGKPSSLMNP-SLSKPNISPSHSRPPGGSDKLASPMKPVPGTPP- 1217

Query: 301  SSSSLDPSLAGCGGDGSSGSGDA 323
            SS +  P  +G GG   SG+  +
Sbjct: 1218 SSKAKSPISSGSGGSHMSGTSSS 1240


>gi|11138123 cholinergic receptor, nicotinic, alpha 10 [Homo
           sapiens]
          Length = 450

 Score = 34.7 bits (78), Expect = 0.14
 Identities = 30/80 (37%), Positives = 35/80 (43%), Gaps = 9/80 (11%)

Query: 191 CGPEVPPTPPGSHSAFTSSFSFIRLSLG-SAGERGEAEGCPPSREAESHCQSPQEMGAKA 249
           CGP V P P     A+  +     L+ G    ERGE   C  SR  E    SPQ     A
Sbjct: 325 CGPSVRPVP-----AWARALLLGHLARGLCVRERGEP--CGQSRPPELS-PSPQSPEGGA 376

Query: 250 ASLDGPHEDPRCLSRPFSLL 269
               GP  +PRCL R  +LL
Sbjct: 377 GPPAGPCHEPRCLCRQEALL 396


>gi|145699105 connexin40.1 [Homo sapiens]
          Length = 370

 Score = 34.7 bits (78), Expect = 0.14
 Identities = 48/182 (26%), Positives = 63/182 (34%), Gaps = 42/182 (23%)

Query: 28  LPPAACFRRRRLARRPGYMRSSTGPGIGFLSPAVGTLFRFPGGVSGEESHHSESRA--RQ 85
           L    C  RRR+ RRPG              P      R   G SG    H+E R    +
Sbjct: 213 LADLVCSLRRRMRRRPG--------------PPTSPSIRKQSGASG----HAEGRRTDEE 254

Query: 86  CGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGIQLRGGTRLPDRLSWPCGPGSAGWQQ 145
            G +  G    +P    A      S R TS     ++ G T++PD              +
Sbjct: 255 GGREEEG--APAPPGARAGGEGAGSPRRTS-----RVSGHTKIPDE------------DE 295

Query: 146 EFAAMDSSETLDASWEAACS-DGARRVRAAGS--LPSAELSSNSCSPGCGPEVPPTPPGS 202
                 +SE L          + A+  R +GS   PSA  S  +  P C    PP PP S
Sbjct: 296 SEVTSSASEKLGRQPRGRPHREAAQDPRGSGSEEQPSAAPSRLAAPPSCSSLQPPDPPAS 355

Query: 203 HS 204
            S
Sbjct: 356 SS 357


>gi|188536004 zinc finger protein 469 [Homo sapiens]
          Length = 3925

 Score = 33.9 bits (76), Expect = 0.24
 Identities = 45/169 (26%), Positives = 70/169 (41%), Gaps = 19/169 (11%)

Query: 42   RPGYMRSSTGPGIGFLSPAVGTLFRFPGGVSGEESHHS-ESRARQCGLDSRGLLVRSPVS 100
            +P    ++T P     +P VG+L   PGG     SH+S +  ARQ G       V +P S
Sbjct: 1251 KPSGSLANTAPHGSSPTPGVGSLLGGPGGTQAPVSHNSKDPPARQPG--EFLAPVANPSS 1308

Query: 101  KSAAAPTVTSVRGTSAHFGIQLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASW 160
             +   P+V S + +S  FG    G  R P  +     P +    Q +++  S   L    
Sbjct: 1309 TACPKPSVLSSKISS--FGCDPAGFNRDPLGV-----PVAKKGPQPYSSPHSELFLGPKD 1361

Query: 161  EAACSDGARRVRAAGSLPSAELSSNSC-------SPGCGPEVPPTPPGS 202
             A C      +    S   A  +S+SC       +    P++P +PPG+
Sbjct: 1362 LAGCF--LEELHPKPSARDAPPASSSCLCQDGEDAGSLEPQLPRSPPGT 1408


>gi|186700623 Rab-like GTP-binding protein 1 isoform 1 [Homo
           sapiens]
          Length = 729

 Score = 33.1 bits (74), Expect = 0.41
 Identities = 45/178 (25%), Positives = 67/178 (37%), Gaps = 21/178 (11%)

Query: 98  PVSKS--AAAPTVTSVR----GTSAHFGIQLRGGTRLPDRLSWPCGPGSAGWQQEFAAMD 151
           P SK     APT T+      G S   G + R  TR P  +    G  ++  + +     
Sbjct: 502 PASKPRRGTAPTRTAAPPWPGGVSVRTGPEKRSSTRPPAEMEPGKGEQASSSESDPEGPI 561

Query: 152 SSETL-----DASWEAACSDGARRVRAAGSLPSAELSSNSCSPGCGPEVPPTPPG---SH 203
           +++ L     D  +E+  SD  RR   A   P  +  S+      GP  PP PP      
Sbjct: 562 AAQMLSFVMDDPDFESEGSDTQRR---ADDFPVRDDPSDVTDEDEGPAEPPPPPKLPLPA 618

Query: 204 SAFTSSFSFIRLSLGSAGERGEA----EGCPPSREAESHCQSPQEMGAKAASLDGPHE 257
               +      L L  AG +  +    EG  PS+E +   +  +E   KAA     H+
Sbjct: 619 FRLKNDSDLFGLGLEEAGPKESSEEGKEGKTPSKEKKKKKKKGKEEEEKAAKKKSKHK 676


>gi|122692281 hypothetical protein LOC645369 [Homo sapiens]
          Length = 621

 Score = 33.1 bits (74), Expect = 0.41
 Identities = 42/182 (23%), Positives = 61/182 (33%), Gaps = 28/182 (15%)

Query: 161 EAACSDGARRVRAAGSLPSAELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSL--- 217
           EA  S    R   AGS  +A  ++ + +  C    P +PP S    +++ SF+  SL   
Sbjct: 320 EAVYSVYRERSGVAGSRRAAAATAAAAASSCSSPAPCSPPESWGRQSTASSFVDSSLSAF 379

Query: 218 ------GSAGERGEAEGC------PPSREAESHCQ------SPQEMGAKAASLDGPHEDP 259
                 G     G+AEG       PP               S   +     S+ G   +P
Sbjct: 380 ALLPLQGGRDRGGDAEGASCSWQRPPGERGSQEIPRGELDLSMTNLRGAEGSMRGARREP 439

Query: 260 RCLSRPFSLLATRVS----ADLAQAARNSSRPERDMHSLPDMDPGSSSSLDPSLAGCGGD 315
                P   +A R +      L +  R ++   R    LPD     S    PS      D
Sbjct: 440 ---EEPEGAVAARAARGQGGRLPRTGRYAALRRRSTSGLPDYRAPPSPEPPPSPGSADPD 496

Query: 316 GS 317
            S
Sbjct: 497 SS 498


>gi|38158015 mastermind-like 3 [Homo sapiens]
          Length = 1133

 Score = 33.1 bits (74), Expect = 0.41
 Identities = 13/33 (39%), Positives = 19/33 (57%)

Query: 291 MHSLPDMDPGSSSSLDPSLAGCGGDGSSGSGDA 323
           +++ P+  P + SS  P+  GCGG G  G G A
Sbjct: 33  VNNTPNSTPAAPSSNHPAAGGCGGSGGPGGGSA 65


>gi|112821681 G protein-regulated inducer of neurite outgrowth 1
           [Homo sapiens]
          Length = 1008

 Score = 33.1 bits (74), Expect = 0.41
 Identities = 36/147 (24%), Positives = 47/147 (31%), Gaps = 7/147 (4%)

Query: 183 SSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQSP 242
           S    SP      P   PG  S   S       +  S G RG      P+  +     S 
Sbjct: 48  SQQKASPAPPRHTPDQSPGMESRHRSPSGAGEGASCSDGPRGSLACPSPTCFSPQESPSK 107

Query: 243 QEMGAKAASLDG-PHEDPRCLSRPFSLLATRVSAD------LAQAARNSSRPERDMHSLP 295
           + + A  AS+ G P         P S + T   +         +     S  + D  S+ 
Sbjct: 108 ETLEAHGASISGTPEATTSGKPEPVSSVKTEPKSSDDRNPMFLEKMDFKSSKQADSTSIG 167

Query: 296 DMDPGSSSSLDPSLAGCGGDGSSGSGD 322
             DPGSS   DP   G       G GD
Sbjct: 168 KEDPGSSRKADPMFTGKAEPEILGKGD 194


>gi|67089160 promyelocytic leukemia protein isoform 11 [Homo
           sapiens]
          Length = 781

 Score = 32.7 bits (73), Expect = 0.53
 Identities = 34/144 (23%), Positives = 50/144 (34%), Gaps = 16/144 (11%)

Query: 168 ARRVRAAGSLPSAELSSNSCSPGC-GPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEA 226
           AR  R++   P    S     P   GP  P +P      F  + + +    G A ER   
Sbjct: 451 ARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLPNSNHVASGAGEAEERVVV 510

Query: 227 EGCPPSREAESHCQSPQEMG---AKAASLDGPHEDPRCLSRPFSLLATRVSADLA----- 278
                  +AE+ C  P E     +  A     H  P   S   SLL  + ++ L      
Sbjct: 511 ISSSEDSDAENSCMEPMETAEPQSSPAHSSPAHSSPAHSSPVQSLLRAQGASSLPCGTYH 570

Query: 279 -------QAARNSSRPERDMHSLP 295
                  Q A  ++ P+ + HS P
Sbjct: 571 PPAWPPHQPAEQAATPDAEPHSEP 594


>gi|15451765 promyelocytic leukemia protein isoform 9 [Homo sapiens]
          Length = 829

 Score = 32.7 bits (73), Expect = 0.53
 Identities = 34/144 (23%), Positives = 50/144 (34%), Gaps = 16/144 (11%)

Query: 168 ARRVRAAGSLPSAELSSNSCSPGC-GPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEA 226
           AR  R++   P    S     P   GP  P +P      F  + + +    G A ER   
Sbjct: 499 ARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLPNSNHVASGAGEAEERVVV 558

Query: 227 EGCPPSREAESHCQSPQEMG---AKAASLDGPHEDPRCLSRPFSLLATRVSADLA----- 278
                  +AE+ C  P E     +  A     H  P   S   SLL  + ++ L      
Sbjct: 559 ISSSEDSDAENSCMEPMETAEPQSSPAHSSPAHSSPAHSSPVQSLLRAQGASSLPCGTYH 618

Query: 279 -------QAARNSSRPERDMHSLP 295
                  Q A  ++ P+ + HS P
Sbjct: 619 PPAWPPHQPAEQAATPDAEPHSEP 642


>gi|45827771 autoantigen RCD8 [Homo sapiens]
          Length = 1401

 Score = 32.7 bits (73), Expect = 0.53
 Identities = 46/171 (26%), Positives = 67/171 (39%), Gaps = 27/171 (15%)

Query: 166 DGARRVRAAGSLPSAELSSNSCSPGCGP----EVPPTPPGSHSAFTSSFSFIRLSLGSAG 221
           DG+  + ++GSL   + S     PG  P    ++ P  PG     TS+ S          
Sbjct: 662 DGSLTMSSSGSL---QASPRGLLPGLLPAPADKLTPKGPGQVPTATSALSL--------- 709

Query: 222 ERGEAEGCPPSREAESHCQSPQEMGAKAASL--DGPHEDPRCLSRPFSLLATRVSADLAQ 279
           E  E E     + + S  +SP  + + + +L  D P      LSR F   A       + 
Sbjct: 710 ELQEVEPLGLPQASPSRTRSPDVISSASTALSQDIPEIASEALSRGFGSSAPEGLEPDSM 769

Query: 280 AARNSSRPERDMHSLPDMDPGSSSSLDPSLAGCGGDGSSGSGDAHSWDTLL 330
           A+  S+     +H L    P     L P L   G DG  G GD H+  +LL
Sbjct: 770 ASAASA-----LHLLSPR-PRPGPELGPQL---GLDGGPGDGDRHNTPSLL 811


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.131    0.414 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,922,585
Number of Sequences: 37866
Number of extensions: 1038343
Number of successful extensions: 5128
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 179
Number of HSP's that attempted gapping in prelim test: 4856
Number of HSP's gapped (non-prelim): 437
length of query: 369
length of database: 18,247,518
effective HSP length: 104
effective length of query: 265
effective length of database: 14,309,454
effective search space: 3792005310
effective search space used: 3792005310
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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