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Search of human proteins with 61742814
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|61742814 coiled-coil and C2 domain containing 1B [Homo
sapiens]
(858 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|61742814 coiled-coil and C2 domain containing 1B [Homo sapiens] 1687 0.0
gi|96974985 coiled-coil and C2 domain containing 1A [Homo sapiens] 709 0.0
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 72 3e-12
gi|122937382 Fas (TNFRSF6) binding factor 1 [Homo sapiens] 61 4e-09
gi|56676397 ankyrin repeat domain 11 [Homo sapiens] 56 1e-07
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 54 6e-07
gi|163965366 nascent polypeptide-associated complex alpha subuni... 52 2e-06
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 52 3e-06
gi|157785645 SPEG complex locus [Homo sapiens] 51 5e-06
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 51 5e-06
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 49 2e-05
gi|115648142 centrosomal protein 164kDa [Homo sapiens] 49 3e-05
gi|117938759 GNAS complex locus XLas [Homo sapiens] 47 1e-04
gi|219802034 nuclear factor related to kappaB binding protein is... 47 1e-04
gi|23346420 nuclear factor related to kappaB binding protein iso... 47 1e-04
gi|58761548 tau tubulin kinase 1 [Homo sapiens] 46 1e-04
gi|125625322 RALBP1 associated Eps domain containing 2 isoform 2... 46 1e-04
gi|125625326 RALBP1 associated Eps domain containing 2 isoform 1... 46 1e-04
gi|171906567 peripheral benzodiazepine receptor-associated prote... 45 2e-04
gi|58082089 hypothetical protein LOC161394 [Homo sapiens] 45 2e-04
gi|38176300 nestin [Homo sapiens] 45 3e-04
gi|210032580 SET domain containing 1B [Homo sapiens] 45 3e-04
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 45 4e-04
gi|148229134 ring finger and KH domain containing 2 [Homo sapiens] 45 4e-04
gi|226437579 NAC alpha domain containing [Homo sapiens] 44 6e-04
gi|239754540 PREDICTED: NAC alpha domain containing [Homo sapiens] 44 6e-04
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 44 6e-04
gi|169205253 PREDICTED: hypothetical protein [Homo sapiens] 44 6e-04
gi|239749105 PREDICTED: NAC alpha domain containing [Homo sapiens] 44 6e-04
gi|239743134 PREDICTED: NAC alpha domain containing [Homo sapiens] 44 6e-04
>gi|61742814 coiled-coil and C2 domain containing 1B [Homo sapiens]
Length = 858
Score = 1687 bits (4370), Expect = 0.0
Identities = 858/858 (100%), Positives = 858/858 (100%)
Query: 1 MMPGPRPRKGPQARGQGVAAAKQMGLFMEFGPEDMLLGMDEAEDDEDLEAELLALTGEAQ 60
MMPGPRPRKGPQARGQGVAAAKQMGLFMEFGPEDMLLGMDEAEDDEDLEAELLALTGEAQ
Sbjct: 1 MMPGPRPRKGPQARGQGVAAAKQMGLFMEFGPEDMLLGMDEAEDDEDLEAELLALTGEAQ 60
Query: 61 TTGKKPAPKGQAPLPMAHIEKLAADCMRDVEEEEEEEGLEEDAELLTELQEVLGVDEETE 120
TTGKKPAPKGQAPLPMAHIEKLAADCMRDVEEEEEEEGLEEDAELLTELQEVLGVDEETE
Sbjct: 61 TTGKKPAPKGQAPLPMAHIEKLAADCMRDVEEEEEEEGLEEDAELLTELQEVLGVDEETE 120
Query: 121 PLDGDEVADPGGSEEENGLEDTEPPVQTAVLTASAPAAQAGASQGLHALLEERIHNYREA 180
PLDGDEVADPGGSEEENGLEDTEPPVQTAVLTASAPAAQAGASQGLHALLEERIHNYREA
Sbjct: 121 PLDGDEVADPGGSEEENGLEDTEPPVQTAVLTASAPAAQAGASQGLHALLEERIHNYREA 180
Query: 181 AASAKEAGEAAKARRCERGLKTLESQLASVRRGRKINEDEIPPPVALGKRPLAPQEPANR 240
AASAKEAGEAAKARRCERGLKTLESQLASVRRGRKINEDEIPPPVALGKRPLAPQEPANR
Sbjct: 181 AASAKEAGEAAKARRCERGLKTLESQLASVRRGRKINEDEIPPPVALGKRPLAPQEPANR 240
Query: 241 SPETDPPAPPALESDNPSQPETSLPGISAQPVSDLDPDPRALLSSRQREYKVAALSAKRA 300
SPETDPPAPPALESDNPSQPETSLPGISAQPVSDLDPDPRALLSSRQREYKVAALSAKRA
Sbjct: 241 SPETDPPAPPALESDNPSQPETSLPGISAQPVSDLDPDPRALLSSRQREYKVAALSAKRA 300
Query: 301 GELDRARELMRIGKRFGAVLEALEKGQPVDLSAMPPAPEDLKPQQASQAPTAPSVIPPAV 360
GELDRARELMRIGKRFGAVLEALEKGQPVDLSAMPPAPEDLKPQQASQAPTAPSVIPPAV
Sbjct: 301 GELDRARELMRIGKRFGAVLEALEKGQPVDLSAMPPAPEDLKPQQASQAPTAPSVIPPAV 360
Query: 361 ERVQPVMAPDVPATPVAPTESQTVLDALQQRLNKYREAGIQARSGGDERKARMHERIAKQ 420
ERVQPVMAPDVPATPVAPTESQTVLDALQQRLNKYREAGIQARSGGDERKARMHERIAKQ
Sbjct: 361 ERVQPVMAPDVPATPVAPTESQTVLDALQQRLNKYREAGIQARSGGDERKARMHERIAKQ 420
Query: 421 YQDAIRAHRAGRKVNFAELPVPPGFPPIPGLESTMGVEEDAVAATLAAAEKLASAEDSAP 480
YQDAIRAHRAGRKVNFAELPVPPGFPPIPGLESTMGVEEDAVAATLAAAEKLASAEDSAP
Sbjct: 421 YQDAIRAHRAGRKVNFAELPVPPGFPPIPGLESTMGVEEDAVAATLAAAEKLASAEDSAP 480
Query: 481 ADKDEDEPPGHLQGEPPAQAPVAKKPARPTVPSSQRLPEPRASSSKESPSPSVREQLALL 540
ADKDEDEPPGHLQGEPPAQAPVAKKPARPTVPSSQRLPEPRASSSKESPSPSVREQLALL
Sbjct: 481 ADKDEDEPPGHLQGEPPAQAPVAKKPARPTVPSSQRLPEPRASSSKESPSPSVREQLALL 540
Query: 541 EARKLQYQRAALQAKRSQDLEQAKAYLRVAKWLEAQIIQARSGRPVDLSKVPSPLTDEEG 600
EARKLQYQRAALQAKRSQDLEQAKAYLRVAKWLEAQIIQARSGRPVDLSKVPSPLTDEEG
Sbjct: 541 EARKLQYQRAALQAKRSQDLEQAKAYLRVAKWLEAQIIQARSGRPVDLSKVPSPLTDEEG 600
Query: 601 DFILIHHEDLRLSQKAEEVYAQLQKMLLEQQEKCLLFSKQFMHQGNVAETTRFEKLAQDR 660
DFILIHHEDLRLSQKAEEVYAQLQKMLLEQQEKCLLFSKQFMHQGNVAETTRFEKLAQDR
Sbjct: 601 DFILIHHEDLRLSQKAEEVYAQLQKMLLEQQEKCLLFSKQFMHQGNVAETTRFEKLAQDR 660
Query: 661 KKQLEILQLAQAQGLDPPTHHFELKTFQTVRIFSELNSTEMHLIIVRGMNLPAPPGVTPD 720
KKQLEILQLAQAQGLDPPTHHFELKTFQTVRIFSELNSTEMHLIIVRGMNLPAPPGVTPD
Sbjct: 661 KKQLEILQLAQAQGLDPPTHHFELKTFQTVRIFSELNSTEMHLIIVRGMNLPAPPGVTPD 720
Query: 721 DLDAFVRFEFHYPNSDQAQKSKTAVVKNTNSPEFDQLFKLNINRNHRGFKRVIQSKGIKF 780
DLDAFVRFEFHYPNSDQAQKSKTAVVKNTNSPEFDQLFKLNINRNHRGFKRVIQSKGIKF
Sbjct: 721 DLDAFVRFEFHYPNSDQAQKSKTAVVKNTNSPEFDQLFKLNINRNHRGFKRVIQSKGIKF 780
Query: 781 EIFHKGSFFRSDKLVGTAHLKLERLENECEIREIVEVLDGRKPTGGKLEVKVRLREPLSG 840
EIFHKGSFFRSDKLVGTAHLKLERLENECEIREIVEVLDGRKPTGGKLEVKVRLREPLSG
Sbjct: 781 EIFHKGSFFRSDKLVGTAHLKLERLENECEIREIVEVLDGRKPTGGKLEVKVRLREPLSG 840
Query: 841 QDVQMVTENWLVLEPRGL 858
QDVQMVTENWLVLEPRGL
Sbjct: 841 QDVQMVTENWLVLEPRGL 858
>gi|96974985 coiled-coil and C2 domain containing 1A [Homo sapiens]
Length = 951
Score = 709 bits (1831), Expect = 0.0
Identities = 408/865 (47%), Positives = 546/865 (63%), Gaps = 74/865 (8%)
Query: 8 RKGPQAR-GQGVAAAKQMGLFMEFGPEDMLLGMDEAEDDEDLEAELLALTGEAQTTGKKP 66
RKGP G+G AAA+Q+GL ++ P+ +++ D A +DE+LEAE LAL G G+ P
Sbjct: 4 RKGPPGPPGRGAAAARQLGLLVDLSPDGLMIPEDGA-NDEELEAEFLALVG-----GQPP 57
Query: 67 AP---KGQAPLPMAHIEKLAADCMRDVEEEEEE----EGLEEDAELLTELQEVLGVDEET 119
A KG+ PLPM IEK+A+ CMRD +E+EEE + LE D +LL EL EVLG
Sbjct: 58 ALEKLKGKGPLPMEAIEKMASLCMRDPDEDEEEGTDEDDLEADDDLLAELNEVLG----- 112
Query: 120 EPLDGDEVADPGGSEEENGLEDTEPPVQTAVLTASAPAAQAGASQGLHALLEERIHNYRE 179
EE +T PPV A P GL L+ER+ Y+
Sbjct: 113 ---------------EEQKASETPPPVAQPKPEAPHP--------GLETTLQERLALYQT 149
Query: 180 AAASAKEAGEAAKARRCERGLKTLESQLASVRRGRKINEDEIPPPVALGKRPL------- 232
A SA++AG++AK RR +RGLKTLE+ LAS+R+G I+E +IPPPVA+GK P
Sbjct: 150 AIESARQAGDSAKMRRYDRGLKTLENLLASIRKGNAIDEADIPPPVAIGKGPASTPTYSP 209
Query: 233 APQEPANRSPETDPPAPPALESDNPSQPETSLPGISA--QPVSDLDPDPRALLSSRQREY 290
AP +PA R P LE + + P +S PG++ P P P A L SRQR+Y
Sbjct: 210 APTQPAPRIASAPEPRV-TLEGPSATAPASS-PGLAKPQMPPGPCSPGPLAQLQSRQRDY 267
Query: 291 KVAALSAKRAGELDRARELMRIGKRFGAVLEALEKGQPVDLSAMPPAPEDLKPQQASQAP 350
K+AAL AK+ G+ A R+ K F AVLEAL +G+PVDLS +PP P+ L P S
Sbjct: 268 KLAALHAKQQGDTTAAARHFRVAKSFDAVLEALSRGEPVDLSCLPPPPDQLPPDPPS--- 324
Query: 351 TAPSVIPPAVERVQPVMAPDVPATPVAPTESQTVLDALQQRLNKYREAGIQARSGGDERK 410
PP+ QP P+T P +T+L+AL+QR+ +Y+ A QA+S GD+RK
Sbjct: 325 ------PPS----QPPTPATAPSTTEVPPPPRTLLEALEQRMERYQVAAAQAKSKGDQRK 374
Query: 411 ARMHERIAKQYQDAIRAHRAGRKVNFAELPVPPGFPPIPGLESTMGVEEDAVAATLAAAE 470
ARMHERI KQYQDAIRAH+AGR V+ AELPVPPGFPPI GLE+T ++ V L A
Sbjct: 375 ARMHERIVKQYQDAIRAHKAGRAVDVAELPVPPGFPPIQGLEATKPTQQSLVGV-LETAM 433
Query: 471 KLASAEDSAPADKDEDEPPGHLQGEPPAQAPVAKKPARPTVPSSQRLPEPRASSSKESPS 530
KLA+ +D P D++++ P Q P A K P T S P A + ++ S
Sbjct: 434 KLAN-QDEGPEDEEDEVPKK--QNSPVAPTAQPKAPPSRTPQSGSA---PTAKAPPKATS 487
Query: 531 PSVREQLALLEARKLQYQRAALQAKRSQDLEQAKAYLRVAKWLEAQIIQARSGRPVDLSK 590
++QLA LE RK Q +AAL+AK+ D+E AK +LR AK LE + +R+G PVD++K
Sbjct: 488 TRAQQQLAFLEGRKKQLLQAALRAKQKNDVEGAKMHLRQAKGLEPMLEASRNGLPVDITK 547
Query: 591 VPSPLTDEEGDFILIHHEDLRLSQKAEEVYAQLQKMLLEQQEKCLLFSKQFMHQGNVAET 650
VP P + DF L+ LSQ+A Y +L K++ +Q E CL S QF GN+ ET
Sbjct: 548 VP-PAPVNKDDFALVQRPGPGLSQEAARRYGELTKLIRQQHEMCLNHSNQFTQLGNITET 606
Query: 651 TRFEKLAQDRKKQLEILQLAQAQGLDPPTHHFELKTFQTVRIFSELNSTEMHLIIVRGMN 710
T+FEKLA+D K+ ++IL+ A +GL PT FE +TF ++IF +L+S +M L IV+G+N
Sbjct: 607 TKFEKLAEDCKRSMDILKQAFVRGLPTPTARFEQRTFSVIKIFPDLSSNDMLLFIVKGIN 666
Query: 711 LPAPPGVTPDDLDAFVRFEFHYPNSDQAQKSKTAVVKNTNSPEFDQLFKLNINRNHRGFK 770
LP PPG++P DLD FVRF+F YPN ++AQK KT+V+KNT+SPEF + FKL INR+HRGF+
Sbjct: 667 LPTPPGLSPGDLDVFVRFDFPYPNVEEAQKDKTSVIKNTDSPEFKEQFKLCINRSHRGFR 726
Query: 771 RVIQSKGIKFEIFHKGSFFRSDKLVGTAHLKLERLENECEIREIVEVLDGRKPTGGKLEV 830
R IQ+KGIKFE+ HKG F++D+++GTA LKL+ LE CE+REI+EVLDGR+PTGG+LEV
Sbjct: 727 RAIQTKGIKFEVVHKGGLFKTDRVLGTAQLKLDALEIACEVREILEVLDGRRPTGGRLEV 786
Query: 831 KVRLREPLSGQDVQMVTENWLVLEP 855
VR+REPL+ Q ++ TE WLV++P
Sbjct: 787 MVRIREPLTAQQLETTTERWLVIDP 811
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 71.6 bits (174), Expect = 3e-12
Identities = 119/569 (20%), Positives = 229/569 (40%), Gaps = 44/569 (7%)
Query: 45 DEDLEAELLALTGEAQTTGKKPAP----KGQAPLPMA--HIEKLAADCMRDVEEEEEEEG 98
D ++ A L GE G P P +G +P HI+ + + ++ VE+ E+E
Sbjct: 396 DIEIAAYRKLLEGEECRIGFGPIPFSLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETV 455
Query: 99 LEEDAELLTELQEVLGVDEETEPLDGDEVADPGGSEE--ENGLEDTE-PPVQTAVLTASA 155
+ E+ T++ E + +EE E + + + GG EE E G E+T+ PP + A++
Sbjct: 456 IVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAE----EAAS 511
Query: 156 PAAQAGASQGLHALLEERIHNYREAAASAK-EAGEAAKARRCERGLKTLESQLASVRRGR 214
P +A + ++E + EA + K EA A+ + E+ + + S +
Sbjct: 512 PEKEAKSP------VKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAK 565
Query: 215 KINEDEIPPPVALGKRPLAPQEPANRSPETDPPAPPALESDNPSQPETSLPGISAQPVSD 274
++E P + K P + PA ++ A ++ +P + E P + PV +
Sbjct: 566 SPEKEEAKSPAEV-KSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKE 624
Query: 275 LDPDPRALLSSRQRE--YKVAALSAKRA--GELDRARELMRIGKRFGAVLEALEKGQPVD 330
P + S + + K A S ++A E + A+ + A ++ EK +
Sbjct: 625 EAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKS-P 683
Query: 331 LSAMPPAPEDLKPQQASQAPTAPSVIPPAVERVQPVMAPDVPATPVAPTESQTVLDALQQ 390
+ A +PE K +A + P E + +P+ +PV E++T ++
Sbjct: 684 VKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAK---SPEKAKSPV-KEEAKTP----EK 735
Query: 391 RLNKYREAGIQARSGGDERKARMHERIAKQYQDAIRAHRAGRKVNFAELPVPPGFPPIPG 450
+ +E KA+ + + + + + F E P +
Sbjct: 736 AKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKS 795
Query: 451 LESTMG-VEEDAVAATLAAAEKLASAEDSAPADKDEDEPPGHLQGEPPAQAPVAKKPARP 509
E ++EDA A +++ E+ K+E++P EPP +A K PA P
Sbjct: 796 PEKAKSPLKEDA----KAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATP 851
Query: 510 TVPSSQRLPEPRASSSKESPSPSVREQLALLEARKLQYQRAALQAKRSQDLEQAKAYLRV 569
+ + A KE+P P V E+ E + + + ++AK+ ++ E K
Sbjct: 852 KTEEKKDSKKEEA-PKKEAPKPKVEEK---KEPAVEKPKESKVEAKK-EEAEDKKKVPTP 906
Query: 570 AKWLEAQIIQARSGRPVDLSKVPSPLTDE 598
K A++ +P + ++V D+
Sbjct: 907 EKEAPAKVEVKEDAKPKEKTEVAKKEPDD 935
Score = 35.8 bits (81), Expect = 0.17
Identities = 89/473 (18%), Positives = 169/473 (35%), Gaps = 51/473 (10%)
Query: 41 EAEDDEDLEAELLALTGEAQTTGKKPAPKGQAPLPMAHIEKLAADCMRDVEEEEEEEG-L 99
EA+ E EA+ A + + ++P EK + + + E + +
Sbjct: 563 EAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPV 622
Query: 100 EEDAELLTELQEVLGVDEET-EPLDGDEVADPGGSEEENGLEDTEPPVQTAVLT---ASA 155
+E+A+ E++ T E E A EE E + PV+ + A +
Sbjct: 623 KEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKS 682
Query: 156 PA-AQAGASQGLHALLEERIHNYREAAASAKEAGEAAKARRCERGLKTLESQLASVRRGR 214
P A+A + + + ++E + +A + KE +A+ E+ ++ + + + +
Sbjct: 683 PVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKE-----EAKSPEKAKSPVKEEAKTPEKAK 737
Query: 215 KINEDEIPPPVALGKRPLAPQEPANRSPETDPPAPPALESDNPSQPETSLPGISAQPVSD 274
++E P K P + +SPE PA S P P + PV +
Sbjct: 738 SPVKEEAKSPEK-AKSPEKAKTLDVKSPEAKTPAKEEARS-----PADKFPEKAKSPVKE 791
Query: 275 LDPDPRALLSSRQREYKVAALSAKRAGELDRARELMRIGKRFGAVLEALEKGQPV----D 330
P S + + K E+ + E+ K E K P +
Sbjct: 792 EVKSPEKAKSPLKEDAKAPEK------EIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEE 845
Query: 331 LSAMPPAPEDLKPQQASQAPTAPSVIPPAVERVQPVM--------------APDVPATPV 376
+ P E+ K + +AP + P E+ +P + A D P
Sbjct: 846 KAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPT 905
Query: 377 APTESQTVLDALQQRLNKYREAGIQARSGGDERKARMHERIAKQYQDAIRAHRAGRKVNF 436
E+ ++ + K +E A+ D+ KA+ + A++ + A + K
Sbjct: 906 PEKEAPAKVEVKEDA--KPKEKTEVAKKEPDDAKAKEPSKPAEKKEAA--PEKKDTKEEK 961
Query: 437 AELPVPPGFPPIPGLESTMGVEEDAVAATLAAAEKLASAEDSAPADKDEDEPP 489
A+ P P E+ E+D + + K AE S+ D+ + +PP
Sbjct: 962 AKKPEEK-----PKTEAK-AKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPP 1008
>gi|122937382 Fas (TNFRSF6) binding factor 1 [Homo sapiens]
Length = 1133
Score = 61.2 bits (147), Expect = 4e-09
Identities = 95/359 (26%), Positives = 133/359 (37%), Gaps = 45/359 (12%)
Query: 330 DLSAMPPAPEDLKPQQASQAPTAPSVIPPAVERVQPVMAPDVPATPVAPTESQTVLDALQ 389
DL P +P + + S P PSV PPA + P P A P PTE A
Sbjct: 351 DLDLFPASPTR-EAHRESSVPVTPSVPPPASQHSTPAGLPPSRAKP--PTEG-AGSPAKA 406
Query: 390 QRLNKYREAGIQARSGGDERKARMHERIAKQYQDAIRAHRAGRKVNFAELPVPPGFPPIP 449
+ +K R S ++ H K+ Q R AG L G PP
Sbjct: 407 SQASKLR------ASKEEKEDWLSHALSRKKSQGLAREQHAGTSEGL-HLAGTAGHPPSG 459
Query: 450 G--LESTMGVEEDAVAATLAAAEK----LASAEDSAPADKD------------EDEPPGH 491
L ST G+E A + + + +P ++ PG
Sbjct: 460 SQPLTSTQGLEHAAAGGSSGTTARERPCVRPGVSGSPVTQNHAASALPTGSPKRGTAPGD 519
Query: 492 LQGEPPAQA-PVAKKPARPTVPSSQRLPEPRASSSKESPSPSVREQLALLEAR-KLQYQR 549
L PA P +KP P+VP LPE S S PS Q LL A+ +LQ
Sbjct: 520 LSATEPATCFPSTQKPTEPSVPVQPLLPE----SLARSLLPSTEYQKQLLAAQVQLQCSP 575
Query: 550 AALQAKRSQDLEQAKAYLRVAKWLEAQIIQARSGRPVDLSKVPSPLTDEEGDFILIHHED 609
A LQA E + R+A+ LEAQ+ + R + S + D LI
Sbjct: 576 AELQA------ELLHSQARLAE-LEAQVRKLELERAQHELLLGSLQQQHQADLELIESAH 628
Query: 610 LRLSQKAEEVYAQLQKMLLEQQEKCLLFSKQFMHQGNVAETTRFEKLAQDRKKQLEILQ 668
+ E Y Q ++ L + E+ S +++ Q AE R E AQ +++ I Q
Sbjct: 629 RSRIKVLETSYQQREERLRRENEE---LSARYLSQCQEAEQARAELTAQHQRRLAAIAQ 684
Score = 31.2 bits (69), Expect = 4.3
Identities = 110/530 (20%), Positives = 190/530 (35%), Gaps = 106/530 (20%)
Query: 179 EAAASAKEAGEAAKARRCER----GLKTLESQLASVRRGRKINEDEIPPPVALGKRPLAP 234
E AA+ +G A+ R C R G ++ AS P KR AP
Sbjct: 470 EHAAAGGSSGTTARERPCVRPGVSGSPVTQNHAASAL------------PTGSPKRGTAP 517
Query: 235 -----QEPANRSPETDPPAPPALESDNPSQPETS----LPG-------ISAQPVSDLDPD 278
EPA P T P P++ P PE+ LP ++AQ P
Sbjct: 518 GDLSATEPATCFPSTQKPTEPSVPVQ-PLLPESLARSLLPSTEYQKQLLAAQVQLQCSPA 576
Query: 279 P--RALLSSRQREYKVAALSAK-RAGELDRARELMRIG---KRFGAVLEALEKGQPVDLS 332
LL S+ R +A L A+ R EL+RA+ + +G ++ A LE +E +
Sbjct: 577 ELQAELLHSQAR---LAELEAQVRKLELERAQHELLLGSLQQQHQADLELIESAHRSRIK 633
Query: 333 AMPPA-----------PEDLKPQQASQAPTAPSVIPPAVERVQPVMAP-----DVPATPV 376
+ + E+L + SQ A + Q +A D +
Sbjct: 634 VLETSYQQREERLRRENEELSARYLSQCQEAEQARAELTAQHQRRLAAIAQEKDQEMERL 693
Query: 377 APTESQTVLDALQ------QRLNKYREAGIQARSGGDERKARMHERIAKQYQDAIRAHRA 430
+ ++LD + QRL ++ + A + ++ I + + + H
Sbjct: 694 RELQRASILDMRRDHEEQLQRLKLLKDREVDAATSATSHTRSLNSIIHQMEKFSSSLHEL 753
Query: 431 GRKVNFAELPVPPGFPPIPGLESTMGVEEDAVAATLAAAEKLASAEDSAPADKDEDEPPG 490
+V + L E +G+ + E+L + ++ + + E
Sbjct: 754 SSRVEASHLTTSQ--------ERELGIRQ--------RDEQLRALQERLGQQQRDMEEER 797
Query: 491 HLQGEPPAQAPVAKKPARPTVPSSQRLPEPR----ASSSKESPSPSVREQLALLEARKLQ 546
Q Q + K AR S+ L + R A SK E+ + A+++
Sbjct: 798 SRQ-----QEVIGKMEARLN-EQSRLLEQERWRVTAEQSKAESMQRALEEQRKVTAQQMA 851
Query: 547 YQRAALQAKRSQDLEQAKAYL---------RVAKWLE--AQIIQARSGRPVDLSKVPSPL 595
+RA L+ +S LE+ K+ + A+W E AQ ++ + +
Sbjct: 852 MERAELERAKSALLEEQKSVMLKCGEERRRLAAEWAEFSAQQKLSKERAEREAERALQVD 911
Query: 596 TDEEGDFILIHHEDLRLSQKAEEVYAQ-----LQKMLLEQQEKCLLFSKQ 640
T EG I + E L +A E+ A+ ++ LEQ+ + L K+
Sbjct: 912 TQREGTLISLAKEQAELKIRASELRAEEKQLAAERAALEQERQELRLEKE 961
>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
Length = 2663
Score = 56.2 bits (134), Expect = 1e-07
Identities = 115/477 (24%), Positives = 176/477 (36%), Gaps = 111/477 (23%)
Query: 222 PPPVALGKRPLAPQEPANRSPETDPPAPPALESDN--------------------PSQPE 261
P P + + P P PA+ +P P A P LE PS E
Sbjct: 2005 PGPFSASEAPY-PAPPASPAPYALPVAEPGLEDVKDGVDAVPAAISTSEAAPYAPPSGLE 2063
Query: 262 TSLPGISAQPVSDLD--PDPRALLSSRQREYKVAALSAKRAGELDRARELMRIGK----- 314
+ + P + LD P+P + + Q V AL LD +R L +G+
Sbjct: 2064 SFFSNCKSLPEAPLDVAPEPACVAAVAQ----VEALGPLENSFLDGSRGLSHLGQVEPVP 2119
Query: 315 ---RFGAVLEALEKGQPVDLSAMPPAPEDL-----KPQQASQAPTAPSVIPPAVERV--- 363
F + L+ G P L +P +D +P + S AP P +PP V
Sbjct: 2120 WADAFAGPEDDLDLG-PFSLPELPLQTKDAADGEAEPVEESLAP--PEEMPPGAPGVING 2176
Query: 364 ---QPVMAPDVPATPVAPTESQTVLDAL-------QQRLNKYREAGIQARSGGDERKARM 413
V+A + PA P P ++ T L A + +L+ EA ++A + +ER
Sbjct: 2177 GDVSTVVAEEPPALP--PDQASTRLPAELEPEPSGEPKLDVALEAAVEAETVPEERA--- 2231
Query: 414 HERIAKQYQDAIRAHRAGRKVNFAELPVPPGFPPIPGLESTMGVE-EDAVAATLAAAEKL 472
R + PVPP P+ G E E AA+L A +
Sbjct: 2232 ---------------RGDPDSSVEPAPVPPEQRPLGS--GDQGAEAEGPPAASLCAPDGP 2274
Query: 473 A--------SAEDSAPADKDE--------DEPPGHLQGEPPAQAPVAKKPARPTVPS-SQ 515
A +A+ + P D E + PPG +Q E P A+ P P V Q
Sbjct: 2275 APNTVAQAQAADGAGPEDDTEASRAAAPAEGPPGGIQPEAAEPKPTAEAPKAPRVEEIPQ 2334
Query: 516 RLPEPRA----SSSKESPSPSVRE------QLALLEARKLQYQRAALQAKR----SQDLE 561
R+ RA + SK+ P PS +E + +AR + A Q R + +
Sbjct: 2335 RMTRNRAQMLANQSKQGPPPSEKECAPTPAPVTRAKARGSEDDDAQAQHPRKRRFQRSTQ 2394
Query: 562 QAKAYLRVAKWLEAQIIQARSGRPVDLSKVPSPLTDEEGDFILIHHEDLRLSQKAEE 618
Q + L + ++IQ VD K+ + + D + E L++ +K EE
Sbjct: 2395 QLQQQLNTSTQQTREVIQQTLAAIVDAIKLDA-IEPYHSDRANPYFEYLQIRKKIEE 2450
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 53.9 bits (128), Expect = 6e-07
Identities = 119/532 (22%), Positives = 189/532 (35%), Gaps = 72/532 (13%)
Query: 91 EEEEEEEGLEEDAELLTELQEVLGVDEETEPLDGDEVADPGGSEEENGLEDTEPP----- 145
E + E EG+E E + QE G E +P D A E + ED E P
Sbjct: 1843 EAQPESEGVEAP-EAEGDAQEAEG---EAQPESEDVEAPEAEGEAQPESEDVETPEAEWE 1898
Query: 146 VQTAVLTASAPAAQAGASQGLHALLEERIHNYREAAASAKEAGEAAKARRCERGLKTLES 205
VQ A AP A+ A ++ E + EA EA +A + G ES
Sbjct: 1899 VQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPES 1958
Query: 206 QLASVRRGRKINEDEIPPPVALGKRPLAPQEPANRSPET-DPPAPPA----LESDNPSQP 260
++ + + + E AL + PE+ D AP A E++ +QP
Sbjct: 1959 EVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQP 2018
Query: 261 ETSLPGISAQPVSDLDPDPRALLSSRQREYKVA----ALSAKRAGELDRARELMRIGKRF 316
E+ G+ AQP S+ + +++ E + A A E + E G+
Sbjct: 2019 ESD--GVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAE----GEVQ 2072
Query: 317 GAVLEALEKGQPVDLS-----AMPPAPEDLKPQQASQAPTAPSVIPPAVE-RVQP----V 366
A EA + + VD A P + P+ +A A + P E QP +
Sbjct: 2073 EAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGI 2132
Query: 367 MAPDVPATPVAPTESQTVLDALQQRLNKYREAGIQARSGGDERKARMHERIAKQYQDAIR 426
AP+ +E DA + + GI+A+ +E + + A + + +
Sbjct: 2133 EAPEAEGEAQPESEGVEAQDAEGEA--QPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQ 2190
Query: 427 AHRAGRKVNFAELPVPPGF-------------PPIPGLES--------------TMGVEE 459
G + AE P P G+E+ T G ++
Sbjct: 2191 PESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKK 2250
Query: 460 DAVAATLAAAEKLASAEDSAPADKDEDEPPGHLQGEPPAQAPVAKKPARPTVPSSQRLPE 519
+ +L + ++E S+P +D PP G+ P Q +P T PSS R
Sbjct: 2251 GSPQVSLGDGQSEEASESSSPVPEDRPTPPPSPGGDTPHQ-----RPGSQTGPSSSRASS 2305
Query: 520 PRASSSKESPSPSVREQLALLEARKLQYQRAALQAKR----SQDLEQAKAYL 567
K+S + V +A+ A +A R S EQ +A L
Sbjct: 2306 WGNCWQKDSENDHVLGDTRSPDAKSTGTPHAERKATRMYPESSTSEQEEAPL 2357
Score = 51.2 bits (121), Expect = 4e-06
Identities = 92/381 (24%), Positives = 145/381 (38%), Gaps = 52/381 (13%)
Query: 9 KGPQARGQGVAAAKQMGLFMEFGPEDMLLGMDEAEDDEDLEAE-LLALTGEAQTTGKKPA 67
+G +A+ AA + G + PE ++ EAE++ E+E + AL E +T
Sbjct: 1936 EGAEAQEAEEAAQEAEG---QTQPESEVIESQEAEEEAQPESEDVEALEVEVETQ----E 1988
Query: 68 PKGQAPLPMAHIEKLAADC-MRDVEEEEEEEGLEEDAELLTELQEVLGVDEETEPLDGDE 126
+G+A +E A+ M++ EEE + E +A+ +E +E V+ ET+ +GD
Sbjct: 1989 AEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDA 2048
Query: 127 VADPGG---SEEENGLEDTEPPVQTAVLTASAPAAQAGASQGLHALLEERIHNYREAAAS 183
+ G E E ++ E VQ A A + A + E E +
Sbjct: 2049 QPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEA-----EGEAQPESEGVEA 2103
Query: 184 AKEAGEAAKARRCERGLKTLESQLASVRRGRKINEDEIPP---------------PVALG 228
+ GEA KA E E+Q S E E P P + G
Sbjct: 2104 PEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEG 2163
Query: 229 KRPLAPQEPAN------RSPETDPPAPP------ALESDNPSQPETSLPGISA-QPVSDL 275
+E A +PE + A P A E++ +QPE L G+ A + +
Sbjct: 2164 IEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPE--LEGVEAPEAEEEA 2221
Query: 276 DPDPRALLSSRQREYKVAALSAKRAGELDRARELMRIGKRFGAVLEALEKGQPV--DLSA 333
P+P + + + GE + + +G G EA E PV D
Sbjct: 2222 QPEPEGVETPEAEGEAQPESEGETQGE-KKGSPQVSLGD--GQSEEASESSSPVPEDRPT 2278
Query: 334 MPPAPEDLKPQQASQAPTAPS 354
PP+P P Q + T PS
Sbjct: 2279 PPPSPGGDTPHQRPGSQTGPS 2299
Score = 37.4 bits (85), Expect = 0.060
Identities = 51/204 (25%), Positives = 76/204 (37%), Gaps = 33/204 (16%)
Query: 87 MRDVEEEEEEEGLEEDAELLTELQEVLGVDEETEPL-DGDEVADPGGSEEENGLEDTEPP 145
+ + +E E EGL+E+A L E + G+ EE L + E G EEE LE+ E
Sbjct: 1303 LEETKEGTEGEGLQEEAVQLEETKTEEGLQEEGVQLEETKETEGEGQQEEEAQLEEIE-- 1360
Query: 146 VQTAVLTASAPAAQAGASQGLHALLEERIHNYREAAASAKEAGEAAKARRCERGLKTLES 205
G L EE + E E G +A E GLK
Sbjct: 1361 -----------------ETGGEGLQEEGVQ--LEEVKEGPEGGLQGEA--LEEGLKEEGL 1399
Query: 206 QLASVRRGRKINEDEIPPPVALGKRPLAPQEPANRSPETDPPAPPALESDNPSQPETSLP 265
G++++E P + +E A R+ + P PA ++ P++P + L
Sbjct: 1400 PEEGSVHGQELSEASSPDGKGSQEDDPVQEEEAGRASASAEPC-PAEGTEEPTEPPSHL- 1457
Query: 266 GISAQPVSDLDPDPRALLSSRQRE 289
S+ DP S Q E
Sbjct: 1458 -------SETDPSASERQSGSQLE 1474
Score = 35.8 bits (81), Expect = 0.17
Identities = 47/185 (25%), Positives = 70/185 (37%), Gaps = 28/185 (15%)
Query: 90 VEEEEEEEGLEEDAELLTELQEVLGVDEETEPLDGDEVADPGGSEEENGLEDTEPPVQTA 149
+EE + EEGL+E+ L E +E G ++ E +E+ + GG GL+ +
Sbjct: 1322 LEETKTEEGLQEEGVQLEETKETEGEGQQEEEAQLEEIEETGG----EGLQ------EEG 1371
Query: 150 VLTASAPAAQAGASQGLHALLEERIHNY---REAAASAKEAGEAAKARRCERGLKTLESQ 206
V G QG LEE + E + +E EA+ G + E
Sbjct: 1372 VQLEEVKEGPEGGLQG--EALEEGLKEEGLPEEGSVHGQELSEASS----PDGKGSQEDD 1425
Query: 207 LASVRRGRKINEDEIPPPVALGKRPLAPQEPANRSPETDPPAPPALESDNPSQPETSLPG 266
+ + P P + P EP + ETDP A E + SQ E PG
Sbjct: 1426 PVQEEEAGRASASAEPCP---AEGTEEPTEPPSHLSETDPSAS---ERQSGSQLE---PG 1476
Query: 267 ISAQP 271
+ P
Sbjct: 1477 LEKPP 1481
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 52.0 bits (123), Expect = 2e-06
Identities = 80/323 (24%), Positives = 122/323 (37%), Gaps = 44/323 (13%)
Query: 231 PLAPQE-PANRSPETDPPAPPALESDNPSQPETSLPGISAQPVSDLDPDPRALLSSRQRE 289
P +P+E PA S DP AP A + P T P + P + P P+ + +
Sbjct: 1510 PSSPKEVPATPSSRRDPIAPTATLLSKKT-PATLAPKEALIPPAMTVPSPKKTPAIPTPK 1568
Query: 290 YKVAALSAKRAGELDRARELMRIGKRFGAVLEALEKGQPVDLSAM-PPAPEDLKPQQASQ 348
A S+K A AV + KG P + PPA P++A
Sbjct: 1569 EAPATPSSKEASSPP-------------AVTPSTYKGAPSPKELLIPPAVTSPSPKEA-- 1613
Query: 349 APTAPSVIPPAVERVQPVMAP-----DVPATPVAPTESQTVLDALQQRLN---KYREAGI 400
PT P+V PP+ E+ AP P TP + +S T ++ ++ G+
Sbjct: 1614 -PTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGL 1672
Query: 401 QARSGGDERKARMHERIAKQYQDAIRAHRAGRKVNFAELPVPPGFPPIPGLESTMGVEED 460
A+ G K + + R G + + PP P + G
Sbjct: 1673 PAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKG---- 1728
Query: 461 AVAATLAAAEKLASAEDSAPADKDED---EPPGHLQGEPPAQAPVAKKPARPTVPSS--Q 515
+T+A A L +DS+ K +D P G L AP K + P ++ +
Sbjct: 1729 -PLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPL-------APPESKASTPLTAAAFEK 1780
Query: 516 RLPEPRASSSKESPSPSVREQLA 538
LP+P ++S +PSP V LA
Sbjct: 1781 VLPKPESASVSAAPSPPVSLPLA 1803
Score = 40.0 bits (92), Expect = 0.009
Identities = 75/336 (22%), Positives = 107/336 (31%), Gaps = 39/336 (11%)
Query: 223 PPVALGKRPLAPQEPANRSPETDPPAPPALESDNPSQPETSLP---------GISAQPVS 273
PP G P + A +P PP+P + P + + P G++ P
Sbjct: 1110 PPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPK 1169
Query: 274 DLDPDPRALLSSRQREYKVAALSAKRAGELDRARELMRIGKRFGAVLEALEKGQPVDLSA 333
P A S + +A S K A A G + KG P +A
Sbjct: 1170 GAPTTPAATPPSPKGG--LATPSPKGAPTTPAATP----PSPKGGLATPSPKGAPTTPAA 1223
Query: 334 MPPAPED-LKPQQASQAPTAPSVIPPAVERVQPVMAPDVPATPVAPTESQTVLDALQQRL 392
PP+P+ L APT P+ PP+ P P P APT +L
Sbjct: 1224 TPPSPKGGLATPSPKGAPTTPAATPPS-----PKGGPATPPPKGAPTPPAATPPSL---- 1274
Query: 393 NKYREAGIQARSGGDERKARMHERIAKQYQDAIRAHRAGRKVNFAELPVP---PGFPPIP 449
+ G+ + + + A + A P P PG PP
Sbjct: 1275 ----KGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPK 1330
Query: 450 GLESTMGVEEDAV--AATLAAAEKLASAEDSAPADKDEDEPPGHLQGEPPAQAPVAKKPA 507
G + V + TL A + + P+ K+ PP A P
Sbjct: 1331 GAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPK 1390
Query: 508 R-PTVPSSQRLPEPRA----SSSKESPSPSVREQLA 538
R P +PS + P A S K +P RE A
Sbjct: 1391 RGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAA 1426
Score = 40.0 bits (92), Expect = 0.009
Identities = 80/372 (21%), Positives = 114/372 (30%), Gaps = 90/372 (24%)
Query: 202 TLESQLASVRRGRKINEDEIPPPVALGKRPLAPQEPANRSPETDPPAP------------ 249
+L+ LA+ N + PP G +P + A P PP+P
Sbjct: 1273 SLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGA 1332
Query: 250 -------PALESDNPSQPET--SLPGISAQPVSDLDPDPRALLSSRQREYKVAALSAKRA 300
P P+ P T S G P S P P A S + + S KR
Sbjct: 1333 PTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRG 1392
Query: 301 GELDRARELMRIGKRFGAVLEALEKGQPVDLSAMP----PAPEDLKPQQASQAPTAPSVI 356
+ KG P + +P AP ++ + P+ +
Sbjct: 1393 PAIPS------------------PKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLT 1434
Query: 357 PPAVERVQPVMAPDV------PATPVAPTESQTVLDALQQRLNKYREAGIQARSGGDERK 410
PPAV V AP PATP ++ L A+ K A Q + +K
Sbjct: 1435 PPAVTPVSLKKAPATSAPKGGPATP--SSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKK 1492
Query: 411 ARMHERIAKQYQDAIRAHRAGRKVNFAELPVPPGFPPIPG--------LESTMGVEEDAV 462
A P P G P +P + +T D +
Sbjct: 1493 A-------------------------PATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPI 1527
Query: 463 AATLAAAEKLASAEDSAPADKDEDEPPGHLQGEPPAQAPVAKKPARPTVPSSQRLPEPRA 522
A T A L+ + A K+ PP P + P PSS+ P A
Sbjct: 1528 APT---ATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPA 1584
Query: 523 ---SSSKESPSP 531
S+ K +PSP
Sbjct: 1585 VTPSTYKGAPSP 1596
Score = 36.6 bits (83), Expect = 0.10
Identities = 39/162 (24%), Positives = 57/162 (35%), Gaps = 22/162 (13%)
Query: 223 PPVALGKRPLAPQEPANRSPETDPPAPPALESDNPSQPETSLPGISAQPVSDLDPDPRAL 282
P L P P+ + T P A P P+ P P + P + P P+
Sbjct: 1060 PAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPS---PKGAPMPPAATPPSPKGG 1116
Query: 283 LSSRQREYKVAALSAKRAGELDRARELMRIGKRFGAVLEALEKGQPVDLSAMPPAPE-DL 341
L++ + +A G + KG P +A PP+P+ L
Sbjct: 1117 LATPPHKGAPTTPAATPPSPK-------------GGLATPPPKGAPTTPAATPPSPKGGL 1163
Query: 342 KPQQASQAPTAPSVIPPA----VERVQPVMAPDVP-ATPVAP 378
APT P+ PP+ + P AP P ATP +P
Sbjct: 1164 ATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSP 1205
Score = 31.2 bits (69), Expect = 4.3
Identities = 19/56 (33%), Positives = 24/56 (42%), Gaps = 2/56 (3%)
Query: 480 PADKDEDEPPGHLQGEP--PAQAPVAKKPARPTVPSSQRLPEPRASSSKESPSPSV 533
P KD P L+G P PAQA + K +P Q P+ S S SP +
Sbjct: 527 PTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEI 582
Score = 30.4 bits (67), Expect = 7.3
Identities = 19/56 (33%), Positives = 27/56 (48%), Gaps = 6/56 (10%)
Query: 325 KGQPVDLSAMPPAPEDLKPQQASQ-APTAPSVIPPAVERVQPVMAPDVPATPVAPT 379
KG P +A PP+P+ + + APT P+ PP+ P P P+ APT
Sbjct: 937 KGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPS-----PKGGPATPSPKGAPT 987
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 51.6 bits (122), Expect = 3e-06
Identities = 82/379 (21%), Positives = 129/379 (34%), Gaps = 74/379 (19%)
Query: 227 LGKRPLAPQEPANRSPETDPPAPPALESDNPSQPETSLPGISAQPVSDLD------PDPR 280
LG R + P P +P + PP+ P S NP+ P + P + PVS D P P+
Sbjct: 654 LGDRFVIPPHPKVPAPFSPPPSKP--RSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQ 711
Query: 281 ALLSSRQREYKVAALSAKRAGELDRARELMRIGKRFGAVLEALEKGQPVDLSAM------ 334
L+ Q ++ + K+ V+EA + +
Sbjct: 712 TTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPP 771
Query: 335 --PPAPE-------DLKPQQ------ASQAPTAPSVIPPAVE------------RVQPVM 367
PPAPE D P + AS P PS P V ++QP
Sbjct: 772 PPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPG 831
Query: 368 APDVPATPVAPTESQTVLDALQQRLNKYREAGIQARSGGDERKARMHERIAKQYQDAIRA 427
+PD P P AP + + + +L + G ++ GG R+ + +R
Sbjct: 832 SPDPPPAPPAPAPASSAPGHVA-KLPQKEPVGC-SKGGGPPREDVGAPLVTPSLLQMVRL 889
Query: 428 HRAGRKVNFAELPVPPGFP-------------PIPGLESTMGVEEDAVAATLAAAEKLAS 474
G + P P P+P S + A +LAA+E L+S
Sbjct: 890 RSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSS 949
Query: 475 AEDSAPADKDEDEPPG--------------HLQGE----PPAQAPVAKKPARPTVPSSQR 516
A+ + P + + P LQ E P QA + + S++
Sbjct: 950 AQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQ 1009
Query: 517 LPEPRASSSKESPSPSVRE 535
P S ++P P R+
Sbjct: 1010 RPPQAPKKSPKAPPPVARK 1028
Score = 47.0 bits (110), Expect = 8e-05
Identities = 110/489 (22%), Positives = 170/489 (34%), Gaps = 99/489 (20%)
Query: 123 DGDEVADPGGSEEENGLEDTEPPVQTAVLTASAPAAQAGASQGLHAL-LEERIHNYREAA 181
DG ++ GGSE + P + + P Q G+ +G + +
Sbjct: 428 DGSTLSSKGGSEGQ--------PESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIR 479
Query: 182 ASAKEAGEAAKARRC--------------ERGLKTLESQLASVRRGRKINEDEIPPPVAL 227
+S + +G + R+ +RGL + L + + + ++P P
Sbjct: 480 SSGQLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTT 539
Query: 228 GKRPLA-----PQEPAN---------------RSPET--DPPAPPALESDNPSQPETSLP 265
G A P PAN RSPE P + + +S P+ P L
Sbjct: 540 GGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLA 599
Query: 266 GISAQPVSDLDPDPRALLSSRQREYKVAAL------SAKRAGELDRA--RELMRIGKRFG 317
G A P P P + S R V++ S+ DR+ + L +G RF
Sbjct: 600 GPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRF- 658
Query: 318 AVLEALEKGQPVDLSAMPPAPEDLKPQQASQAPTAPSVIPPAVERVQPVMAPDVPATPVA 377
+ V PP + P A+ A AP+V+P PV D A+P +
Sbjct: 659 ----VIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPG------PVSTTD--ASPQS 706
Query: 378 PTESQTVLDALQQRLNKYREAGIQARSGGDERKARMHERIAKQYQDAIRAHRAGRKVNFA 437
P QT L LQ+ ++ Q+ K+ + + A A A
Sbjct: 707 PPTPQTTLTPLQESPVISKD---QSPPPSPPPSYHPPPPPTKKPEVVVEAPSASET---A 760
Query: 438 ELPV-----PPGFPPI------------PGLESTMGVEEDAVAATLAAAEKLAS-AEDSA 479
E P+ PP PP P E+ V A + E ++S A S+
Sbjct: 761 EEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSS 820
Query: 480 PADKDEDEPPGHLQ--GEPPAQAP-------VAKKPARPTVPSSQRLPEPRASSSKESPS 530
A + +PPG PPA AP VAK P + V S+ PR +
Sbjct: 821 SATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVT 880
Query: 531 PSVREQLAL 539
PS+ + + L
Sbjct: 881 PSLLQMVRL 889
>gi|157785645 SPEG complex locus [Homo sapiens]
Length = 3267
Score = 50.8 bits (120), Expect = 5e-06
Identities = 88/371 (23%), Positives = 143/371 (38%), Gaps = 39/371 (10%)
Query: 177 YREAAASAKEAGEAAKARRCERGLKTLESQLASVRRGRKINEDEIPPPVALGKRPLAPQE 236
YR A S + + RR E L+ QLAS R PPP K L P
Sbjct: 263 YRGRALSIHVSVPQSGLRREE---PDLQPQLASEAPRRPAQ----PPP---SKSALLPP- 311
Query: 237 PANRSPETDPPAPPALESDNPSQP--ETSLPGISAQPVSD-------LDPDPRALLSSRQ 287
P+ R + PP PPA + P+ P T P + ++ P ++
Sbjct: 312 PSPRVGKRSPPGPPAQPAATPTSPHRRTQEPVLPEDTTTEEKRGKKSKSSGPSLAGTAES 371
Query: 288 REYKVAALSAKRAGELDRARELMRIGKRFGAVLEAL-EKGQPVDLSAMPPAPEDLKPQQA 346
R + ++ R L R+ L+R G R L+ E+ + ++ S PPAP L+P
Sbjct: 372 RPQTPLSEASGRLSALGRSPRLVRAGSRILDKLQFFEERRRSLERSDSPPAP--LRPWVP 429
Query: 347 SQAPTAPSVIPPAVERVQPVMAPDVPATPVAPTESQTVLDALQQRLNKYREAGIQARSGG 406
+ A S+ P ER P P + S L Q+ + + RS
Sbjct: 430 LR--KARSLEQPKSERGAPWGTPGASQEELRAPGSVAERRRLFQQKAASLDERTRQRSPA 487
Query: 407 DERKARMHERIAK-----QYQDAIRAHRAGR-KVNFAELPVPPGFPPIPGLESTMGVEED 460
+ + R + + + ++ +R+H + R + A P PG PP+ ST +
Sbjct: 488 SDLELRFAQELGRIRRSTSREELVRSHESLRATLQRAPSPREPGEPPLFSRPST---PKT 544
Query: 461 AVAATLAAAEKLASAEDSAPADKDEDEPPGHLQGEPPAQAPVAKKPARPTVPSSQRLPEP 520
+ A + AAA+ + + P D+ PG + PA + + V + P
Sbjct: 545 SRAVSPAAAQPPSPSSAEKPGDE-----PGRPRSRGPAGRTEPGEGPQQEVRRRDQFPLT 599
Query: 521 RASSSKESPSP 531
R+ + +E SP
Sbjct: 600 RSRAIQECRSP 610
Score = 40.0 bits (92), Expect = 0.009
Identities = 60/274 (21%), Positives = 94/274 (34%), Gaps = 50/274 (18%)
Query: 340 DLKPQQASQAPTAPSVIPPAVERVQPVMAPDV--------PATPVAPTES---QTVLDAL 388
DL+PQ AS+AP P+ PP+ + P +P V PA P A S +T L
Sbjct: 285 DLQPQLASEAPRRPAQPPPSKSALLPPPSPRVGKRSPPGPPAQPAATPTSPHRRTQEPVL 344
Query: 389 QQRLNKYREAGIQARSGGDERKARMHERIAKQYQDAIRAHRAGRKVNFAELPVPPGFPPI 448
+ + G +++S G R +A
Sbjct: 345 PEDTTTEEKRGKKSKSSGPSLAGTAESRPQTPLSEA------------------------ 380
Query: 449 PGLESTMGVEEDAVAATLAAAEKLASAEDSAPADKDEDEPPGHLQGEPPAQAPVAKKPAR 508
G S +G V A +KL E+ + + D PP L+ P + A+ +
Sbjct: 381 SGRLSALGRSPRLVRAGSRILDKLQFFEERRRSLERSDSPPAPLRPWVPLRK--ARSLEQ 438
Query: 509 PTVPSSQRLPEPRASSSKESPSPSVREQLALLEARKLQYQRAALQAKRSQDLEQAKAYLR 568
P P AS + SV E+ L + + Q + DLE LR
Sbjct: 439 PKSERGAPWGTPGASQEELRAPGSVAERRRLFQQKAASLDERTRQRSPASDLE-----LR 493
Query: 569 VAKWL--------EAQIIQARSGRPVDLSKVPSP 594
A+ L +++++ L + PSP
Sbjct: 494 FAQELGRIRRSTSREELVRSHESLRATLQRAPSP 527
Score = 39.7 bits (91), Expect = 0.012
Identities = 86/344 (25%), Positives = 126/344 (36%), Gaps = 74/344 (21%)
Query: 230 RPLAPQEPANRSPETDPPAPPALESDNPSQPETSLPGI------SAQPVSDLD-PDPRAL 282
RPL P+ +R TD P E + PET P D + P P AL
Sbjct: 1937 RPLQPEFSGSRVSLTDIPT----EDEALGTPETGAATPMDWQEQGRAPSQDQEAPSPEAL 1992
Query: 283 LSSRQREYKVAALSAKRAGELDRARE----LMRIGKRFGAVLEALEKGQPVDLSAMPPAP 338
S Q AA ++ R GEL R L R G R + L K V+L
Sbjct: 1993 PSPGQEP---AAGASPRRGELRRGSSAESALPRAGPR--ELGRGLHKAASVEL------- 2040
Query: 339 EDLKPQQASQAPTAPSVIPPAVERVQPVMAPDVPATPVAPTESQTVLDALQQRLNKY--- 395
PQ+ S +P A + + E L AL+QRL +
Sbjct: 2041 ----PQRRSPSPGATRLARGGL----------------GEGEYAQRLQALRQRLLRGGPE 2080
Query: 396 --REAGIQA----RSGGDERKARM----HERIAKQYQDAIRAHRAGRKVNFAELPVPP-- 443
+ +G++ GG R RM A +Q + + +F++ P
Sbjct: 2081 DGKVSGLRGPLLESLGGRARDPRMARAASSEAAPHHQPPLENRGLQKSSSFSQGEAEPRG 2140
Query: 444 ----GFPPIPGLESTMGVEEDAVAATLAAAEKLASAEDSAPADKDEDEPPGHLQGEPPAQ 499
P+ + +G + +L+A L+ A+ S+PA +P EP A
Sbjct: 2141 RHRRAGAPLEIPVARLGARRLQESPSLSA---LSEAQPSSPARPSAPKPSTPKSAEPSAT 2197
Query: 500 APV-AKKPARPTVPSSQRLPEPR---ASSSKESPSPSVREQLAL 539
P A +P P P+ + PEPR +SK +P P + LAL
Sbjct: 2198 TPSDAPQPPAPQ-PAQDKAPEPRPEPVRASKPAPPPQALQTLAL 2240
Score = 32.7 bits (73), Expect = 1.5
Identities = 67/283 (23%), Positives = 106/283 (37%), Gaps = 38/283 (13%)
Query: 161 GASQGLHALLEE----RIHNYREAAASAKEAGEAAKARRCERGLKTLES--QLASVRRGR 214
G GL L E R + R A A++ EA + RGL+ S Q + RGR
Sbjct: 2082 GKVSGLRGPLLESLGGRARDPRMARAASSEAAPHHQPPLENRGLQKSSSFSQGEAEPRGR 2141
Query: 215 KINEDE-IPPPVA-LGKRPLAPQEPANRSPETDPPAPPALESDNPSQPETSLPGISAQPV 272
+ PVA LG R L + E P +P + PS P+++ P +
Sbjct: 2142 HRRAGAPLEIPVARLGARRLQESPSLSALSEAQPSSPARPSAPKPSTPKSAEPSATTPSD 2201
Query: 273 SDLDPDPRALLSSRQREYKVAALSAKRAGELDRARELMRIGKRFGAVLEALEKGQPVDLS 332
+ P P+ ++K A + L + ++++L+
Sbjct: 2202 APQPPAPQPAQDKAPEPRPEPVRASKPAPPPQALQTLALPLTPYAQIIQSLQLSGHAQGP 2261
Query: 333 AMPPA--PEDLKP------QQASQAPTAPSVIPPAVERVQPVMA-----PDVPATP---- 375
+ PA P + KP + AS P AP P+ PV+A P VP P
Sbjct: 2262 SQGPAAPPSEPKPHAAVFARVASPPPGAPEKRVPSAGG-PPVLAEKARVPTVPPRPGSSL 2320
Query: 376 ---VAPTESQTVLDALQQRLNKYREAGIQ------ARSGGDER 409
+ ES+ V +A + + RE+ + +RS +ER
Sbjct: 2321 SSSIENLESEAVFEA---KFKRSRESPLSLGLRLLSRSRSEER 2360
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 50.8 bits (120), Expect = 5e-06
Identities = 88/402 (21%), Positives = 145/402 (36%), Gaps = 70/402 (17%)
Query: 313 GKRFGAVLEALEKGQPVDLSAMPPAPEDLKPQQASQAPTAPSVIPPAVERVQPV------ 366
G +G +L +G D + P A + P+ AS +P P + +V R P
Sbjct: 333 GPTWGRAGASLARGPQPDRTH-PSAAVPVCPRSASASPLTPCSVTRSVHRCAPAGERGER 391
Query: 367 MAPDVPATPVAPTESQTVLDALQQRLNKYREAGIQARSGGDERKARMHERIAKQYQDAIR 426
P+ +P AP + +Q++ K +E R E+ A ER K+ Q
Sbjct: 392 RKPNAGGSP-APVRRRPEASPVQKKEKKDKE-----RENEKEKSALARERSLKKRQSLPA 445
Query: 427 AHRAGRKVNFAELPVP---------------PGFP-PIPGLESTMGVEEDAVAATLAAA- 469
+ RA + A P P P P PG T+ + + T A+
Sbjct: 446 SPRARLSASTASELSPKSKARPSSPSTSWHRPASPCPSPGPGHTLPPKPPSPRGTTASPK 505
Query: 470 -------EKLASAEDSAPADKDEDE-------------------PPGHLQGEPPAQAPVA 503
E S + P DK + + P P + P A
Sbjct: 506 GRVRRKEEAKESPSAAGPEDKSQSKRRASNEKESAAPASPAPSPAPSPTPAPPQKEQPPA 565
Query: 504 KKPARPTVPSSQRLPEPRASSSKESPSPSVREQLALLEARKLQYQRAALQAKRSQDLEQA 563
+ P V +S P P + SK + RE+ L A K + R + + + QA
Sbjct: 566 ETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEATRLLAEKRRQAREQREREEQERRLQA 625
Query: 564 KAYLRVAKWLEAQIIQARSGRPVDLSKVPSPLTDEEGDFILIHHEDLRLSQKAEEVYAQL 623
+ R+ + A+ +AR+ R + + E+ E RL ++ EE A+
Sbjct: 626 ERDKRMREEQLAREAEARAEREAEARRREEQEAREKAQ--AEQEEQERLQKQKEEAEARS 683
Query: 624 QKMLLEQQEKCLLFSKQFMHQGNVAETTRFEKLAQDRKKQLE 665
++ E + + L K F Q E+ Q+R+K+LE
Sbjct: 684 RE---EAERQRLEREKHFQQQ---------EQERQERRKRLE 713
Score = 33.9 bits (76), Expect = 0.66
Identities = 30/99 (30%), Positives = 41/99 (41%), Gaps = 15/99 (15%)
Query: 480 PADKDEDEPPGHLQGEPPAQAPVAKKPARPTVPSSQRLPEPRASSSKESPSPSVREQLAL 539
PA E+ P + P + + ARP SSQ P P A + +SP P+ +E
Sbjct: 79 PAPPQEESPSSEAKSRGPTPPAMGPRDARPPRRSSQ--PSPTAVPASDSP-PTKQEVKKA 135
Query: 540 LEARKLQYQRAALQAKRSQDLEQAKAYLRVAK--WLEAQ 576
E KL +R +AK YL K WLE +
Sbjct: 136 GERHKLAKERREERAK----------YLAAKKAVWLEKE 164
Score = 30.0 bits (66), Expect = 9.6
Identities = 43/208 (20%), Positives = 73/208 (35%), Gaps = 40/208 (19%)
Query: 246 PPAPPALESDNPSQPETSLPGISAQPVSDLDPDPRALLSSRQREYKVAALSAKRAGELDR 305
PP P +PS P + + D P + SS+Q + + S
Sbjct: 22 PPEPRPSPEGDPSPPPPPMSALVPDTPPDTPPAMKNATSSKQLPLEPESPSG-------- 73
Query: 306 ARELMRIGKRFGAVLEALEKGQPVDLSAMPPA--PEDLKPQQASQAPTAPSV----IPPA 359
++G R E + PPA P D +P + S P+ +V PP
Sbjct: 74 -----QVGPRPAPPQEESPSSEAKSRGPTPPAMGPRDARPPRRSSQPSPTAVPASDSPPT 128
Query: 360 VERVQPV-------------MAPDVPATPVAPTESQTVLDALQQ--------RLNKYREA 398
+ V+ A + A E + AL++ RL + R
Sbjct: 129 KQEVKKAGERHKLAKERREERAKYLAAKKAVWLEKEEKAKALREKQLQERRRRLEEQRLK 188
Query: 399 GIQARSGGDERKARMHERIAKQYQDAIR 426
Q R+ +ER+ + E+ ++Y+ AI+
Sbjct: 189 AEQRRAALEERQRQKLEKNKERYEAAIQ 216
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 48.9 bits (115), Expect = 2e-05
Identities = 183/791 (23%), Positives = 298/791 (37%), Gaps = 151/791 (19%)
Query: 45 DEDLEAELLALTGEAQTTGKKPAPKGQAPLPMAHIEKLAADCMRDVEEEEEEEGL--EED 102
+ED E +L AL EA+T K A G+ + +E+ + R+++E + + E+
Sbjct: 1240 NEDKEQKL-ALLEEARTAVGKEA--GELRTGLQEVERSRLEARRELQELRRQMKMLDSEN 1296
Query: 103 AELLTELQEVLGVDEETEPLDGDEVADPGGSEEENGLEDT----EPPVQTAVLTASAPAA 158
L EL E+ G L E A+ E GL E ++
Sbjct: 1297 TRLGRELAELQG------RLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQR 1350
Query: 159 QAGASQGLHALLEERIHNYREAAASAKEAG-----------EAAKARRCERGLKT----- 202
+ +G E R+ E A ++ EAA+A E GL+
Sbjct: 1351 KLQEQEGEFRTRERRLLGSLEEARGTEKQQLDHARGLELKLEAARAEAAELGLRLSAAEG 1410
Query: 203 ----LESQLASVRRGRKINEDEIPP-------PVALGKRPLAPQEPANRSPETDPPA--- 248
LE++LA V R+ E ++ + LG+ P P SP D PA
Sbjct: 1411 RAQGLEAELARVEVQRRAAEAQLGGLRSALRRGLGLGRAPSPAPRPVPGSPARDAPAEGS 1470
Query: 249 ------PPALESDNPSQPETSLPGISAQPVS-DLDPDP--RAL------LSSRQRE---- 289
P LE SQP + PG + P S DLDP+ AL L S QRE
Sbjct: 1471 GEGLNSPSTLECSPGSQPPS--PGPATSPASPDLDPEAVRGALREFLQELRSAQRERDEL 1528
Query: 290 --------YKVAALSAKRAGELDRARELMRIGKRFGAVLEALEKGQPVD------LSAMP 335
++A + A+R RAR+L + AV E+ E + VD + +
Sbjct: 1529 RTQTSALNRQLAEMEAERDSATSRARQLQK------AVAESEEARRSVDGRLSGVQAELA 1582
Query: 336 PAPEDLKPQQASQAPTAPSVIPPAVERVQPVMAPDVPATPVAPTE---SQTVLDALQQRL 392
E ++ + + T V +ER ++ A+ ++ ++T L+ ++RL
Sbjct: 1583 LQEESVRRSERERRATLDQV--ATLERSLQATESELRASQEKISKMKANETKLEGDKRRL 1640
Query: 393 NKYREAG--------IQARS-GGDERKARM----HERIAKQYQDAIRAHRAGRKVNFAEL 439
+ +A +Q RS G+ +++R+ E A+ QD R R+V +E+
Sbjct: 1641 KEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQD--RVDSLQRQVADSEV 1698
Query: 440 PVPPGFPPIPGLESTMGVEEDAVAA----TLAAAEKLASAEDSAPADKDEDEPPGHLQGE 495
+ L + E++ A E LA + S + +D++ HLQ
Sbjct: 1699 KAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDKNL---HLQ-- 1753
Query: 496 PPAQAPVAKKPARPTVPSSQRLPEPR-ASSSKESPSPSVREQLALL--EARKLQYQRAAL 552
+A A + R + +RL R A S S S+ EQ+ L E L+ QR
Sbjct: 1754 ---KALTACEHDRQVL--QERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEA 1808
Query: 553 QAKRSQDLEQAKAYLRVAKWLEAQIIQARSGRPVDLSKVPSPLTDEEGDFILIHHEDLRL 612
+ + L+Q + LR Q + G L+ V L DE + E L
Sbjct: 1809 EGQ----LQQLREVLR----------QRQEGEAAALNTV-QKLQDER----RLLQERLGS 1849
Query: 613 SQKAEEVYAQLQKMLLEQQEKCLLFSKQFMHQGNVAETTRFEKLAQDRKKQLEILQLAQA 672
Q+A AQL+ E + L K + + EKL R + + A+
Sbjct: 1850 LQRA---LAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKL---RSHEDTVRLSAEK 1903
Query: 673 QGLDPPTHHFELKTFQTVRIFSELNSTEMHLIIVRGMNLPAPPGVTPDDLDAFVRFEFHY 732
LD EL+ + R ++ E ++++ + PA V ++ E
Sbjct: 1904 GRLDRTLTGAELELAEAQR---QIQQLEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVER 1960
Query: 733 PNSDQAQKSKT 743
S QAQ +T
Sbjct: 1961 LRSAQAQTERT 1971
>gi|115648142 centrosomal protein 164kDa [Homo sapiens]
Length = 1460
Score = 48.5 bits (114), Expect = 3e-05
Identities = 123/616 (19%), Positives = 225/616 (36%), Gaps = 142/616 (23%)
Query: 38 GMDEAEDDEDLEAELLA--LTGEAQTTGKKPAPKGQAPLPMAHIEKLAADCMRDVEEEEE 95
G+ E E++E E ++ +T +A TG +PA + P D + E
Sbjct: 309 GLPEKEENEKSEPKICRNLVTPKADPTGSEPAKASEKEAP------------EDTVDAGE 356
Query: 96 EEGLEEDAELLTELQEVLGVDEETEPLDGDEVADPGGSEEENGLEDTE----PPVQTAVL 151
E E+A EP + G S+ LE +E P + ++
Sbjct: 357 EGSRREEAA--------------KEPKKKASALEEGSSDASQELEISEHMKEPQLSDSI- 401
Query: 152 TASAPAAQAGASQGLHALLEERIHNYREAAASAKEAGEAAKARRCERGLKTLESQLASV- 210
AS P + G G + + E + + + G A + + G++ + +S
Sbjct: 402 -ASDPKSFHGLDFGFRSRISEHL---LDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQD 457
Query: 211 ---RRGRKINEDEIPPPVALGKRPLAPQEPANRSPETDPPAPPALESDNPSQPETSLPGI 267
+ K E+ + PP+ +R +P P + + E +PP P QPE
Sbjct: 458 ELQSKQSKGLEERLSPPLPHEERAQSP--PRSLATEEEPPQGPE------GQPEW----- 504
Query: 268 SAQPVSDLDPDPRALLSSRQREYKVAALSAKRAGELDRARELMRIGKRFGAVLEALEKGQ 327
+ +L D A LS + + A S A E GK + E L GQ
Sbjct: 505 --KEAEELGEDSAASLSLQLSLQREQAPSPPAACEK---------GKEQHSQAEELGPGQ 553
Query: 328 PVDLSAMPPAPEDLKPQQASQAPTAPSVIPPAVERVQPVMAPDVPATPVAPTESQTVLDA 387
ED + ++ + +PT P + P V +PV P+ + + V
Sbjct: 554 E--------EAEDPE-EKVAVSPTPP--VSPEVRSTEPVAPPEQLSEAALKAMEEAVAQV 602
Query: 388 LQQRLNKYREAGIQARSGGDERKARMHERIAKQYQDAI-RAHRAGRKVNFAELPVPPGFP 446
L+Q E+ E+ ++ E++ ++ ++ I R H+
Sbjct: 603 LEQDQRHLLESK-------QEKMQQLREKLCQEEEEEILRLHQ----------------- 638
Query: 447 PIPGLESTMGVEEDAVAATLAAAEKLASAEDSAPADKDEDEPPGHLQGEPPAQAPVAKKP 506
+++ ++L + A E+ A ++E + L+ +
Sbjct: 639 -----------QKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQ----------- 676
Query: 507 ARPTVPSSQRLPEPRASSSKESPSPSVREQLALLEARKLQYQRAALQAKRSQDLEQAKAY 566
V SS + E + + +E+ +RE+L + + +RA+L+ K Q LEQ K
Sbjct: 677 ----VQSSTQADEDQIRAEQEASLQKLREELESQQ----KAERASLEQKNRQMLEQLKEE 728
Query: 567 LRVAKWLEAQIIQARSGRPVDLSKVPSPLTDEEGDFILI----HHEDLR-----LSQKAE 617
+ ++ E + A + L ++ L E + + H +L L K
Sbjct: 729 IEASEKSEQAALNAAKEKA--LQQLREQLEGERKEAVATLEKEHSAELERLCSSLEAKHR 786
Query: 618 EVYAQLQKMLLEQQEK 633
EV + LQK + E Q+K
Sbjct: 787 EVVSSLQKKIQEAQQK 802
>gi|117938759 GNAS complex locus XLas [Homo sapiens]
Length = 1037
Score = 46.6 bits (109), Expect = 1e-04
Identities = 90/394 (22%), Positives = 135/394 (34%), Gaps = 61/394 (15%)
Query: 185 KEAGEAAKARRCERGLKTLESQLASVRRGRKINEDEIPPPVALGKRPLAPQEPANRSPET 244
K +G K R ER +E + A + E P G P A A+ +
Sbjct: 338 KVSGAPDKRERAER--PPVEEEAAEMEGAADAAEGGKVPSPGYGS-PAAGAASADTAARA 394
Query: 245 DPPAPPALESDNPSQPETSLPGISAQPVSDLDPDPRALLSSRQREYKVAALSAKRAGELD 304
P AP + D+ + PE G + DPD A + AA + +G
Sbjct: 395 APAAPA--DPDSGATPEDPDSG-----TAPADPDSGAFAADPDSGAAPAAPADPDSGA-- 445
Query: 305 RARELMRIGKRFGAVLEALEKGQPVDLSAMPPAPEDLKPQQASQAPTAPSVIPPAVERVQ 364
A + D A P AP D A +AP AP+ V
Sbjct: 446 -----------------APDAPADPDSGAAPDAPADPDAGAAPEAPAAPAAAETRAAHVA 488
Query: 365 PVMAPDVPATPVAPTESQTVLDALQQRLNKYREAGIQARSGGDERKARMHERIAKQYQDA 424
P APD A P AP S T R + R A A + G RK
Sbjct: 489 PA-APDAGA-PTAPAASAT-------RAAQVRRAASAAPASGARRK-------------- 525
Query: 425 IRAHRAGRKVNFAELPVPPGFPPIPGLESTMGVEEDAVAATLAAAEKLASAEDSAPADKD 484
I ++ A+ P P + G E + + E +AS++D + D+
Sbjct: 526 IHLRPPSPEIQAADPPTPRP----TRASAWRGKSESSRGRRVYYDEGVASSDDDSSGDES 581
Query: 485 EDEPPGHLQGEPPAQAPVAKKPARPTVPSSQRLPEPRASSSKESPSPSVREQLAL----L 540
+D G L+ + +KP R + + ESP P L + L
Sbjct: 582 DDGTSGCLRWFQHRRNRRRRKPQRNLLRNFLVQAFGGCFGRSESPQPKASRSLKVKKVPL 641
Query: 541 EARKLQYQRAALQAKRSQDLEQAKAYLRVAKWLE 574
++ Q ++ AL+ KR+Q + K + K L+
Sbjct: 642 AEKRRQMRKEALE-KRAQKRAEKKRSKLIDKQLQ 674
>gi|219802034 nuclear factor related to kappaB binding protein
isoform 1 [Homo sapiens]
Length = 1299
Score = 46.6 bits (109), Expect = 1e-04
Identities = 61/229 (26%), Positives = 91/229 (39%), Gaps = 26/229 (11%)
Query: 172 ERIHNYREAAASAKEAGEA-------AKARRCERGLKTLESQLASVRRGRKINEDEIPPP 224
ERIH + AAA A++A + K+ E +K L S S + +++ +PP
Sbjct: 660 ERIHQAQAAAAKARKALQQKPKPPSKVKSSSKESSIKVLSSG-PSEQSQMSLSDSSMPPT 718
Query: 225 VALGKRPLAPQEPANRSPETDPPAPPALESDNPSQPET-SLPGISAQPV----SDLDPDP 279
P+ P P + P +PP + + N S P T S P S+ V S P
Sbjct: 719 ------PVTPVTPTTPALPAIPISPPPVSAVNKSGPSTVSEPAKSSSGVLLVSSPTMPHL 772
Query: 280 RALLSSRQREYKVAALSAKRAGELDRARELMRIGKRFGAVLEAL--EKGQPVD-LSAMPP 336
+LS + ++ +A R + L ++ L A+ + G P L MP
Sbjct: 773 GTMLSPASSQTAPSSQAAARVVSHSGSAGLSQVRVVAQPSLPAVPQQSGGPAQTLPQMPA 832
Query: 337 APEDLKPQQASQAPTAPSVIPPAVERVQPVMAPDVPATPVAPTESQTVL 385
P+ P A+Q V+P V PV A AT P QT L
Sbjct: 833 GPQIRVPATATQT----KVVPQTVMATVPVKAQTTAATVQRPGPGQTGL 877
>gi|23346420 nuclear factor related to kappaB binding protein
isoform 2 [Homo sapiens]
Length = 1324
Score = 46.6 bits (109), Expect = 1e-04
Identities = 61/229 (26%), Positives = 91/229 (39%), Gaps = 26/229 (11%)
Query: 172 ERIHNYREAAASAKEAGEA-------AKARRCERGLKTLESQLASVRRGRKINEDEIPPP 224
ERIH + AAA A++A + K+ E +K L S S + +++ +PP
Sbjct: 685 ERIHQAQAAAAKARKALQQKPKPPSKVKSSSKESSIKVLSSG-PSEQSQMSLSDSSMPPT 743
Query: 225 VALGKRPLAPQEPANRSPETDPPAPPALESDNPSQPET-SLPGISAQPV----SDLDPDP 279
P+ P P + P +PP + + N S P T S P S+ V S P
Sbjct: 744 ------PVTPVTPTTPALPAIPISPPPVSAVNKSGPSTVSEPAKSSSGVLLVSSPTMPHL 797
Query: 280 RALLSSRQREYKVAALSAKRAGELDRARELMRIGKRFGAVLEAL--EKGQPVD-LSAMPP 336
+LS + ++ +A R + L ++ L A+ + G P L MP
Sbjct: 798 GTMLSPASSQTAPSSQAAARVVSHSGSAGLSQVRVVAQPSLPAVPQQSGGPAQTLPQMPA 857
Query: 337 APEDLKPQQASQAPTAPSVIPPAVERVQPVMAPDVPATPVAPTESQTVL 385
P+ P A+Q V+P V PV A AT P QT L
Sbjct: 858 GPQIRVPATATQT----KVVPQTVMATVPVKAQTTAATVQRPGPGQTGL 902
>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
Length = 1321
Score = 46.2 bits (108), Expect = 1e-04
Identities = 147/653 (22%), Positives = 221/653 (33%), Gaps = 159/653 (24%)
Query: 4 GPRPRK------GPQARGQGVAAAKQM-GLFMEFGPEDMLLGMDEAEDDEDLE--AELLA 54
GPRPR+ GPQ + VA ++ GL P + L + + DL E
Sbjct: 646 GPRPRRRESDPTGPQRQVFSVAPPFEVNGL-----PRAVPLSLPYQDFKRDLSDYRERAR 700
Query: 55 LTGEAQTTGKKPAPKGQAPLPMAHIEKLAADCMRDVEEEEEEEGLEEDAELLTELQEVLG 114
L + G +P+A ++ A + EEEE+EE EED E
Sbjct: 701 LLNRVRRVGFSHMLLTTPQVPLAPVQPQANGKEEEEEEEEDEEEEEEDEE---------- 750
Query: 115 VDEETEPLDGDEVADPGGSEEENGLEDTEPPVQTAVLTASAPAAQAGASQGLHALLEERI 174
+EE E + +E EEE E+ E A+ P + +S+G E
Sbjct: 751 -EEEEEEEEEEE-------EEEEEEEEEEAAAAVALGEVLGPRS-GSSSEG----SERST 797
Query: 175 HNYREAAASAKEAGEAAKAR----------RCERGLKTLESQLASVRRGRKINEDEIPPP 224
+E A S A + ++R E G KTL + + + P P
Sbjct: 798 DRSQEGAPSTLLADDQKESRGRASMADGDLEPEEGSKTLVLVSPGDMKKSPVTAELAPDP 857
Query: 225 VALGKRPLAPQ--EPANRSPETDPPAPPALESDNPSQPETSLPG---------------- 266
L PQ P + D P L S S+P+ PG
Sbjct: 858 DLGTLAALTPQHERPQPTGSQLDVSEPGTLSSVLKSEPKPPGPGAGLGAGTVTTGVGGVA 917
Query: 267 ISAQPVSDLDPDPRALLSSRQREYKVAALSAKRAGELDRAREL-MRIGKRFGAVLEALE- 324
+++ P + ++ + + A R+ E EL + + GAV E
Sbjct: 918 VTSSPFTKVERTFVHIAEKTHLNVMSSGGQALRSEEFSAGGELGLELASDGGAVEEGARA 977
Query: 325 -----------KGQPVDLSAMPPAPEDLKPQQASQA-PTAPSVI--PPAVERVQPVMAPD 370
G ++ SA+ AP + + A+ + P P++ P V ++P +P+
Sbjct: 978 PLENGLALSGLNGAEIEGSALSGAPRETPSEMATNSLPNGPALADGPAPVSPLEP--SPE 1035
Query: 371 VPAT-----------------PVAPTESQT---------------------------VLD 386
AT PV +E T V++
Sbjct: 1036 KVATISPRRHAMPGSRPRSRIPVLLSEEDTGSEPSGSLSAKERWSKRARPQQDLARLVME 1095
Query: 387 ALQQRLNKYREAGIQARSGGDERKAR-------MHERIAKQYQDAIRAHRAGR-KVNFAE 438
Q RL +G + S ++R+A E A ++GR +
Sbjct: 1096 KRQGRLLLRLASGASSSSSEEQRRASETLSGTGSEEDTPASEPAAALPRKSGRAAATRSR 1155
Query: 439 LPVPPGF-PPIPGLESTMGVEEDAVAATLAAA----EKLASAEDSA-PADKDEDEPPGHL 492
+P P G P+P A L A +L + SA AD +PPG
Sbjct: 1156 IPRPIGLRMPMPVAAQQPASRSHGAAPALDTAITSRLQLQTPPGSATAADLRPKQPPGRG 1215
Query: 493 QGEPPAQAPVAKKPARPTVPSSQRLP-----------EPRAS--SSKESPSPS 532
G AQA ARP P S RLP PR+ S +ESPSPS
Sbjct: 1216 LGPGRAQA-----GARPPAPRSPRLPASTSAARNASASPRSQSLSRRESPSPS 1263
>gi|125625322 RALBP1 associated Eps domain containing 2 isoform 2
[Homo sapiens]
Length = 659
Score = 46.2 bits (108), Expect = 1e-04
Identities = 64/280 (22%), Positives = 113/280 (40%), Gaps = 41/280 (14%)
Query: 320 LEALEKGQPVDLSAMPPAPEDLKPQQASQAPTAPSVIPPAVERVQPVMAPDVPATPVAPT 379
L +EK D++ +P +D+ + + + DV P P
Sbjct: 398 LNRMEKTSVKDMADLPVPNQDVTSDDKQALKST----------INEALPKDVSEDPATPK 447
Query: 380 ESQTVLDALQQRLNKYREAGIQ-ARSGGDE------RKARMHERIA-----KQYQDAIRA 427
+S ++ + R Y I+ A G++ R + H R + K +Q ++ A
Sbjct: 448 DSNSL--KARPRSRSYSSTSIEEAMKRGEDPPTPPPRPQKTHSRASSLDLNKVFQPSVPA 505
Query: 428 HRAGRKVNFAELPVPPGFPPIPGLESTMGVEEDAVAATLAAAEKLASAEDSAPADKD--E 485
++G LP PP PP P + V E + L+ A + A +S+PA KD
Sbjct: 506 TKSGL------LPPPPALPPRPCPSQSEQVSEAELLPQLSRAP--SQAAESSPAKKDVLY 557
Query: 486 DEPPG---HLQGEPPAQAPVAKKPA-RPTVPSSQRLPEPRASSSKESPSPSVREQLALLE 541
+PP + P QA ++P+ + P+S +P + K+S Q A+ +
Sbjct: 558 SQPPSKPIRRKFRPENQATENQEPSTAASGPASAATMKPHPTVQKQSSKQKKAIQTAIRK 617
Query: 542 ARKLQYQRAALQAKRSQDLEQAKAYLRVAKWLEAQIIQAR 581
++ A L ++ Q L++ R+A LE Q+ Q R
Sbjct: 618 NKEANAVLARLNSELQQQLKEVHQE-RIA--LENQLEQLR 654
>gi|125625326 RALBP1 associated Eps domain containing 2 isoform 1
[Homo sapiens]
Length = 660
Score = 46.2 bits (108), Expect = 1e-04
Identities = 64/280 (22%), Positives = 113/280 (40%), Gaps = 41/280 (14%)
Query: 320 LEALEKGQPVDLSAMPPAPEDLKPQQASQAPTAPSVIPPAVERVQPVMAPDVPATPVAPT 379
L +EK D++ +P +D+ + + + DV P P
Sbjct: 399 LNRMEKTSVKDMADLPVPNQDVTSDDKQALKST----------INEALPKDVSEDPATPK 448
Query: 380 ESQTVLDALQQRLNKYREAGIQ-ARSGGDE------RKARMHERIA-----KQYQDAIRA 427
+S ++ + R Y I+ A G++ R + H R + K +Q ++ A
Sbjct: 449 DSNSL--KARPRSRSYSSTSIEEAMKRGEDPPTPPPRPQKTHSRASSLDLNKVFQPSVPA 506
Query: 428 HRAGRKVNFAELPVPPGFPPIPGLESTMGVEEDAVAATLAAAEKLASAEDSAPADKD--E 485
++G LP PP PP P + V E + L+ A + A +S+PA KD
Sbjct: 507 TKSGL------LPPPPALPPRPCPSQSEQVSEAELLPQLSRAP--SQAAESSPAKKDVLY 558
Query: 486 DEPPG---HLQGEPPAQAPVAKKPA-RPTVPSSQRLPEPRASSSKESPSPSVREQLALLE 541
+PP + P QA ++P+ + P+S +P + K+S Q A+ +
Sbjct: 559 SQPPSKPIRRKFRPENQATENQEPSTAASGPASAATMKPHPTVQKQSSKQKKAIQTAIRK 618
Query: 542 ARKLQYQRAALQAKRSQDLEQAKAYLRVAKWLEAQIIQAR 581
++ A L ++ Q L++ R+A LE Q+ Q R
Sbjct: 619 NKEANAVLARLNSELQQQLKEVHQE-RIA--LENQLEQLR 655
>gi|171906567 peripheral benzodiazepine receptor-associated protein
1 isoform b [Homo sapiens]
Length = 1797
Score = 45.4 bits (106), Expect = 2e-04
Identities = 97/451 (21%), Positives = 172/451 (38%), Gaps = 81/451 (17%)
Query: 236 EPANRSPETDPPAPPALESDNPSQPETSLP--GISAQPVSDLDPD-PRALLSSRQREYKV 292
EP++ +P P AL+ E+S P S++PV DP+ A L S ++
Sbjct: 34 EPSSAAPSIADTPPAALQLQELRSEESSKPKGDGSSRPVGGTDPEGAEACLPSLGQQASS 93
Query: 293 AALSAKRAGELD-----RARELMRIGKRFGAVLEALEKGQPVDLSAMPPAPEDLKPQQAS 347
+ + +R + + +A+ M G R L L A+ + +
Sbjct: 94 SGPACQRPEDEEVEAFLKAKLNMSFGDRPNLEL----------LRALGELRQRCAILKEE 143
Query: 348 QAPTAPSVIPPAVERVQPVMAPDVPATPVAPTESQTVLDALQQRLNKYREAGIQARSGGD 407
S P E+V+ + + E + L++R K +E ++ G
Sbjct: 144 NQMLRKSSFPETEEKVRRLKRKNA--------ELAVIAKRLEERARKLQETNLRVE-GPQ 194
Query: 408 ERKARMHERIAKQYQ-DAIRAHRAGRKVNFAE-LPVPPGFPPIPGLESTMGVEEDAVAAT 465
R +R+ ++ Q + +R R N E LP+PP +PP P L++ G
Sbjct: 195 WLHVRDFDRLLRESQREVLRLQRQIALRNQRETLPLPPSWPPGPALQARAGA-------- 246
Query: 466 LAAAEKLASAEDSAPADKDEDEPPGHLQGEPPAQAPVAKKPARPTVPSSQRLPEPRASSS 525
A A +D D P L GEP + QR+ + + S
Sbjct: 247 -----PAPGAPGEATPQEDADNLPVIL-GEPEKE---------------QRVQQLESELS 285
Query: 526 KESPSPSVREQLALLEARKLQYQRAALQAKRSQDLEQAKAYLRVAKWLEAQIIQAR---S 582
K+ EQ EARK Q +R ++LE LR A+ A++++ S
Sbjct: 286 KKRKKCESLEQ----EARKKQ--------RRCEELE---LQLRQAQNENARLVEENSRLS 330
Query: 583 GRPVDLSKVPSPLTDEEGDFILIHHEDLRLSQKAEEVYAQLQKMLLEQQEKCLLFSKQFM 642
GR + +V + G + + E +K++ + ++L+ + E+ L ++
Sbjct: 331 GRATEKEQVEWENAELRGQLLGVTQERDSALRKSQGLQSKLESL-----EQVLKHMREVA 385
Query: 643 HQGNVAETTRFEKLAQDRKKQLEILQLAQAQ 673
+ E + R+KQ E+ +L QAQ
Sbjct: 386 QRRQQLEVEHEQARLSLREKQEEVRRLQQAQ 416
>gi|58082089 hypothetical protein LOC161394 [Homo sapiens]
Length = 674
Score = 45.4 bits (106), Expect = 2e-04
Identities = 73/352 (20%), Positives = 125/352 (35%), Gaps = 35/352 (9%)
Query: 41 EAEDDEDLEAELLALTGEAQTTGKKPAPKGQAPLPMAHIEKLAADCMRDVEEEEEEEGLE 100
E E+++ E E A+ KP Q + + ++ + +E + E
Sbjct: 58 ETEEEDFKEGE----PDSAKNVQLKPGGTSQEGIAKESKRDVPSETEPGIHQEVKSETSR 113
Query: 101 EDAELLTELQEVLGVDEETEPLDGDEVADPGGSEE---ENGLE---DTEPPVQTAVLTAS 154
E E +L+ + + L+ E A P +E+ E+ +E D PP +T +
Sbjct: 114 EMGEFFKDLEAPMDETHKESDLEPPEEAKPNVTEDVFLESAMETDPDPVPPTETMSEVSG 173
Query: 155 APAAQAGASQGLHALLEERIHNYREAAASAKEAGEAAKARRCERGLKTLES---QLASVR 211
A + LLEE E E E+ + + E GL+ E S +
Sbjct: 174 ATVRERNLE-----LLEE------ETEPGVPE--ESLRVQHEETGLEPPEQTKQDFPSEK 220
Query: 212 RGRKINEDEIPPPVALGKRPLAPQEPANRSPE---TDPPAPPALESDNPSQPETSLPGIS 268
G + E ++ PP +P P+E S E T+PP LE +P S
Sbjct: 221 LGESLEETDLQPPKMT--KPETPEETQRESTEKKRTEPPEQARLEF-LEKEPRKSSEEAG 277
Query: 269 AQPVSDLDPDPRALLSSRQREYKVAALSAKRAGELDRARELMRIGKRFGAVLEALEKGQP 328
+P + P+ + + E K L + + + + LE ++ P
Sbjct: 278 LEPPEETQPEVPEEMQRKATEEKGTELPERTKPDFPDHKPRKSTDENVPEPLEEIKLEFP 337
Query: 329 VDLSAMPPAPEDLKPQQASQAPTAPSVIPPAVERVQPVMAPDVPATPVAPTE 380
+ + E + Q P +P I + E+ P P PV P E
Sbjct: 338 EE-ESRKTNEETILEQSEMMKPESPEEIRKSNEKKNP--QPPEETGPVLPQE 386
>gi|38176300 nestin [Homo sapiens]
Length = 1621
Score = 45.1 bits (105), Expect = 3e-04
Identities = 73/306 (23%), Positives = 117/306 (38%), Gaps = 44/306 (14%)
Query: 33 EDMLLGMDEAEDDEDLEA-ELLALTGEAQTTGKKPAPKGQAPLPMAHIEKLAADCMRDVE 91
+D G +E + +L A E + + GE + P PK Q L K A+ ++D E
Sbjct: 985 QDGFTGKEEVVEQGELNATEEVWIPGEGHP--ESPEPKEQRGLVEGASVKGGAEGLQDPE 1042
Query: 92 EEEEEEGLEEDAELLTELQEVLGVDEETEPLDGDEVADPGGSEEENGLEDTEPPVQTAVL 151
+ ++ G LQ G+ E EPL D+VA G + +EP +
Sbjct: 1043 GQSQQVGAPG-------LQAPQGLPEAIEPLVEDDVAPGGDQASPEVMLGSEP-----AM 1090
Query: 152 TASAPAAQAGASQGLHALLEERIHNYREAAASAKEAGEAAKARRCE------------RG 199
SA A+ G QG+ L + H RE E+ +A+R + G
Sbjct: 1091 GESAAGAEPGPGQGVGGLGDPG-HLTREEVMEPPLEEESLEAKRVQGLEGPRKDLEEAGG 1149
Query: 200 LKTLESQLAS--------VRRGRKINEDEIPPPVALGKRPLAPQEPANRSPETDPPAPPA 251
L T S+L R GR+ +E E P G P E + +D P+P
Sbjct: 1150 LGTEFSELPGKSRDPWEPPREGREESEAEAP----RGAEEAFPAETLGHT-GSDAPSPWP 1204
Query: 252 LESDNPSQ---PETSLPGISAQPVSDLDPDPRALLSSRQREYKVAALSAKRAGELDRARE 308
L S+ + P P + P+ + P P+ Q A+ G+++ +E
Sbjct: 1205 LGSEEAEEDVPPVLVSPSPTYTPILEDAPGPQPQAEGSQEASWGVQGRAEALGKVESEQE 1264
Query: 309 LMRIGK 314
+ G+
Sbjct: 1265 ELGSGE 1270
Score = 35.4 bits (80), Expect = 0.23
Identities = 110/522 (21%), Positives = 196/522 (37%), Gaps = 65/522 (12%)
Query: 41 EAEDDEDLEAELLALTGEAQTTGKKPAPKGQAPLPMAHIEKLAADCMRDVEEEEEEEGLE 100
E +D E L T E +T ++ + Q + + EK+ + ++ +++E
Sbjct: 748 EEQDQETLR------TLEKETQQRRRSLGEQDQMTLRPPEKVDLEPLKSLDQEIARPLEN 801
Query: 101 EDAELLTELQEVLGVDEETEPLDG--DEVADPGGSEEENGLEDTEPPVQTAVLTASAPAA 158
E+ E L L+E E E + E+ + S + LE + P A L
Sbjct: 802 ENQEFLKSLKE-----ESVEAVKSLETEILESLKSAGQENLETLKSPETQAPLWTPEEIN 856
Query: 159 QAGASQGLHALLEERIHNYREAAASAKEAGEAAKARRCERGLKTLESQLASVRRGRKINE 218
Q GA L ++E + + + + E + G LE+ L S K ++
Sbjct: 857 Q-GAMNPLEKEIQEPLESVEVNQETFRLLEEENQESLRSLGAWNLEN-LRSPEEVDKESQ 914
Query: 219 DEIPPPVALGKRPLAPQEPANRSPETD----PPAPPALESDNPSQPETSLPGISAQPVSD 274
+ LGK + + RS E + P + ++ + + L S ++
Sbjct: 915 RNLEEEENLGK---GEYQESLRSLEEEGQELPQSADVQRWEDTVEKDQELAQESPPGMAG 971
Query: 275 LDPDPRALLSSRQREYKVAALSAKRAGELDRARELMRIGKRFGAVLEALEKGQPVDLSAM 334
++ + A L+ R+++ GEL+ E+ G+ E E+ V+ +++
Sbjct: 972 VENEDEAELNLREQDGFTGKEEVVEQGELNATEEVWIPGEGHPESPEPKEQRGLVEGASV 1031
Query: 335 PPAPEDLK-PQQASQAPTAPSVIPPA--VERVQPVMAPDVPATPVAPTESQTVLDALQQR 391
E L+ P+ SQ AP + P E ++P++ DV P S V+ +
Sbjct: 1032 KGGAEGLQDPEGQSQQVGAPGLQAPQGLPEAIEPLVEDDV--APGGDQASPEVMLGSEPA 1089
Query: 392 LNKYREAGIQARSG------GDE----RKARMHERIAKQYQDAIRAH-----------RA 430
+ + AG + G GD R+ M + ++ +A R
Sbjct: 1090 MGE-SAAGAEPGPGQGVGGLGDPGHLTREEVMEPPLEEESLEAKRVQGLEGPRKDLEEAG 1148
Query: 431 GRKVNFAELPVPPGFPPIPGLESTMGVEEDAVAATLAAAEKLASAEDSAPADKDEDEPPG 490
G F+ELP P P E G EE + AE AE++ PA E G
Sbjct: 1149 GLGTEFSELPGKSRDPWEPPRE---GREE-------SEAEAPRGAEEAFPA-----ETLG 1193
Query: 491 HLQGEPPAQAPVAKKPARPTVPSSQRLPEPRASS-SKESPSP 531
H + P+ P+ + A VP P P + +++P P
Sbjct: 1194 HTGSDAPSPWPLGSEEAEEDVPPVLVSPSPTYTPILEDAPGP 1235
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 45.1 bits (105), Expect = 3e-04
Identities = 77/325 (23%), Positives = 115/325 (35%), Gaps = 54/325 (16%)
Query: 92 EEEEEEGLEEDAELLTELQEVLGVDEETEPLDGDEVADPGGSEEENGLEDT--------E 143
EE+E+E L E+ E E +E +EE E D D+ E EN EDT +
Sbjct: 1034 EEDEKESLSEEQESTEEEEEA---EEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKD 1090
Query: 144 PPVQTAVLTASAPAAQAGASQGLHALLEERIHNYREAAASAKEAGEAAKARRCERGLK-- 201
T S ++A A+ + + E++ S+ E E AR E +
Sbjct: 1091 EGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEE 1150
Query: 202 --TLESQLASVRRGRKINEDE-------IPPPVALGKRPLAPQEPANRSPET------DP 246
E +AS + E P +LG E +PE +P
Sbjct: 1151 EMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEP 1210
Query: 247 PAPPALESDNPSQPETSLPGISAQPVSDLDPDPRALLSSRQREYKVAALSAKRAGELDRA 306
P P +E S+ PG+S + L P+P A ++ E + LS +RA E D
Sbjct: 1211 PLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPA----KEVEAR-PPLSPERAPEHDLE 1265
Query: 307 RELMRIGKRFGAVLEALEKGQPVDLSAMPPAPEDLKPQQASQAP-------TAPSVIPPA 359
E E + L PP P P+ S P + PSV P
Sbjct: 1266 VE--------------PEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEP 1311
Query: 360 VERVQPVMAPDVPATPVAPTESQTV 384
+ P P + + ++TV
Sbjct: 1312 LAEDHPPHTPGLCGSLAKSQSTETV 1336
Score = 37.4 bits (85), Expect = 0.060
Identities = 60/264 (22%), Positives = 90/264 (34%), Gaps = 53/264 (20%)
Query: 231 PLAPQEPANRSPETDPPAPPALES------------------DNPSQPE-TSLPGISAQP 271
PL P EP + PP PP ++ D+P P S P +P
Sbjct: 436 PLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGPEKP 495
Query: 272 VSDLDPDPRALLSSRQREYKVAALSAKRAGELDRARELMRIGKRFGAVLEALEKGQPVDL 331
LD LL +++ K+ L E D EL G + L P
Sbjct: 496 HDSLDSRIEMLL--KEQRTKLLFLR-----EPDSDTELQMEGSPISSSSSQLSPLAPFGT 548
Query: 332 SAMP----PAPEDLKPQQASQAPTAPSVIPPAVE----------RVQPVMAPDVPATPVA 377
++ P P P +P +P+ +P + E R P P PA ++
Sbjct: 549 NSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPAGLLS 608
Query: 378 PTESQTVLDALQQRLNKYREAGIQARSGGDERKARMHERIAKQYQDAI----------RA 427
T ++ LD + R + +S G++ + E + A A
Sbjct: 609 QT-AEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAA 667
Query: 428 HRAGRKVNFAELPV--PPGFPPIP 449
A V LP+ PPGFPP+P
Sbjct: 668 AVAAPSVLAPTLPLPPPPGFPPLP 691
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 44.7 bits (104), Expect = 4e-04
Identities = 87/344 (25%), Positives = 125/344 (36%), Gaps = 49/344 (14%)
Query: 62 TGKKPAPKGQAPLPMAHIEKLAADCMRDVEEEEEEEGLEEDAELLTELQEVLGVDEETEP 121
T + AP G AP P D D E+ E GL A L +LG + E
Sbjct: 1954 TSGELAPPGPAPSPPP-----PEDLGPDFEDMEVVSGLS--AADLDFAASLLGTEPFQEE 2006
Query: 122 LD-----GDEVADPGGSEEENGLEDTEPPVQTAVLTASAPAAQAGASQGLHALLEERIHN 176
+ G PG S EE T + V SAP A+ G + E++
Sbjct: 2007 IVAAGAMGSSHGGPGDSSEEES-SPTSRYIHFPVTVVSAPGLAPSATPGAPRI--EQLDG 2063
Query: 177 YREAAASAKEAGEAAKARRCERGLKTLESQLASVRRG-------RKINEDEIPPPVA--L 227
+ S EA + RG T S VR G R +++P + +
Sbjct: 2064 VDDGTDSEAEAVQQP------RGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFV 2117
Query: 228 GKRPLAPQEP-ANRSPETDPPAPPALESDNPSQPETSLPGISAQPVSDLDPDPRALLSSR 286
K P + A E+ PPAPP PSQ G++A P DP +
Sbjct: 2118 LKNLGGPGDGGAGPREESLPPAPPLANGSQPSQ------GLTASPA-----DPTRTFAWL 2166
Query: 287 QREYKVAALSAKRAGELDR--ARELMRIGKRFGAVLEALEKGQPVDLSA-MPPAPEDLKP 343
V LS A E + +++ + K ++ +G+PV PP P + P
Sbjct: 2167 PGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISP 2226
Query: 344 QQASQAPTAPSVIPPAVERVQPVMAPDVPATPVAPTESQTVLDA 387
APT+ ++ P + V PV+ PA P P VL +
Sbjct: 2227 ----TAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSS 2266
Score = 44.3 bits (103), Expect = 5e-04
Identities = 96/434 (22%), Positives = 132/434 (30%), Gaps = 109/434 (25%)
Query: 138 GLEDTEPPVQTAVLTASAPAAQAGASQGLHALLEERIHNYREAAASAKEAGEAAKARRCE 197
GLE + Q P + G+ QG +++ + KE E K +
Sbjct: 322 GLESGQGQGQHEESWQDVPQRRVGSGQGGSPCWKKQEQKLDDEEEEKKEEEEKDKEGEEK 381
Query: 198 RGLKTLESQL-ASVRRGRKINEDEIPPPVALGKRPLAPQEPANRSPETDPPAPPALESDN 256
E + A+ + K+ + PP PL P + P PP PP
Sbjct: 382 EERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPL 441
Query: 257 PSQPETSLPGISAQPVSDLDPDPRALLSSRQREYKVAALSAKRAGELDRARELMRIGKRF 316
PS P AQ + P P + ++ + ++RA RE R G
Sbjct: 442 PSPPPP-----PAQEEQEESPPPVVPATCSRKRGRPPLTPSQRA-----EREAARAGP-- 489
Query: 317 GAVLEALEKGQPVDLSAMPPAPEDLKPQQASQAPTAPSVI-------------------- 356
E P +A PED P A ++ T I
Sbjct: 490 ----EGTSPPTPTPSTATGGPPED-SPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPR 544
Query: 357 ---------PPAVERVQPVMAP-------------DVPATPVAPTESQTVLDALQQRLNK 394
PP VE V PV+ P VP+ P APT T + ++R +
Sbjct: 545 RFMDEDPPKPPKVE-VSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSI 603
Query: 395 YREAGIQARSGGDERKARMHERIAKQYQDAIRAHRAGRKVNFAELPVPPGFPPIPGLEST 454
RE + S ELP PP PP P S
Sbjct: 604 LREPTFRWTS------------------------------LTRELPPPPPAPPPPPAPS- 632
Query: 455 MGVEEDAVAATLAAAEKLASAEDSAPADKDEDEPPGHLQ------GEPPAQAPVAKKPAR 508
AT + L A P++ HL+ PP AP A +P
Sbjct: 633 ----PPPAPATSSRRPLLLRAPQFTPSE-------AHLKIYESVLTPPPLGAPEAPEPEP 681
Query: 509 PTVPSSQRLPEPRA 522
P S PEPRA
Sbjct: 682 PPADDSPAEPEPRA 695
Score = 42.4 bits (98), Expect = 0.002
Identities = 109/500 (21%), Positives = 174/500 (34%), Gaps = 98/500 (19%)
Query: 118 ETEPLDGDEVADPGGSEEENGLEDTEPPVQTAVLTASAPAAQAGASQGLHALLEERIHNY 177
E PLD D V PG E + +++ +PP++ +A PA ++ + + ++ NY
Sbjct: 1818 EDPPLDTD-VLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSFSGARI------KVPNY 1870
Query: 178 REAAASAKEAGEAAKARRCERGLKTLESQLASVRRGRKINEDEIPPPVALGKRP--LAPQ 235
+ S + G + G S + + + + P P +RP LAP+
Sbjct: 1871 ---SPSRRPLGGVSFGPLPSPG-----SPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPR 1922
Query: 236 EPANR--------SPETDPPAPPALESD-NPSQPETSLPG--ISAQPVSDLDPDPRALLS 284
P +R SP+ P P ++ + P+ E + PG S P DL PD
Sbjct: 1923 PPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDLGPDFE---- 1978
Query: 285 SRQREYKVAALSAKRAGELDRARELMRIGKRFGAVLEALEKGQPVDLSAMPPAPEDLKPQ 344
+ +S A +LD A L+ ++ A G + P D +
Sbjct: 1979 ------DMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMG------SSHGGPGDSSEE 2026
Query: 345 QASQAPTAPSVIPPAVERVQPVMAPDVPATPVAPTESQTVLDALQQRLNKYREAGIQARS 404
++S PT+ + P P +AP ATP AP Q LD + + EA Q R
Sbjct: 2027 ESS--PTSRYIHFPVTVVSAPGLAPS--ATPGAPRIEQ--LDGVDDGTDSEAEAVQQPRG 2080
Query: 405 ----------------GGDERKARMHERIAKQYQDAIRAHRAGRKVNFA---ELPVPPGF 445
G +AR E + + D + + G A E +PP
Sbjct: 2081 QGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAP 2140
Query: 446 PPIPGLESTMGVEEDAVAATLAAAEKLASAEDSAPADKDEDEPPG--------------- 490
P G + + G+ T A + + EPP
Sbjct: 2141 PLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQV 2200
Query: 491 --HLQGE-----PPAQAPVAKKPARPTVPSSQRLPE-------PRASSSKESPSPSVREQ 536
+ GE PP + P PT P+S LP P + +P P
Sbjct: 2201 FVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPL 2260
Query: 537 LALLEARKLQYQRAALQAKR 556
+L + R A++ KR
Sbjct: 2261 TLVLSSGPASPPRQAIRVKR 2280
Score = 33.1 bits (74), Expect = 1.1
Identities = 82/371 (22%), Positives = 123/371 (33%), Gaps = 106/371 (28%)
Query: 220 EIPPPVALGKRPLAPQEPAN-----------RSPETDPP-----------APPALESDNP 257
E+PPP P AP P R+P+ P PP L + P
Sbjct: 617 ELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGA--P 674
Query: 258 SQPETSLPGISAQPVSDLDPDPRALLSSRQREYKVAALSAKRAGELDRARELMRIGKRFG 317
PE P P +P+PRA+ R L R +
Sbjct: 675 EAPEPEPPPADDSPA---EPEPRAV---------------GRTNHLSLPRFAPVVTTPVK 716
Query: 318 AVLEALEKGQPVDLSAMPPAPEDLKPQQASQAPTAPSVIPPAVERVQPVMAPDVPATPVA 377
A E G P + + L+P QA Q P +PP ++QP P +
Sbjct: 717 A--EVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQP---------PPS 765
Query: 378 PTESQTVLDALQQRLNKYREAGIQA--RSGGDERKARMHERIAKQYQDAIRAHRAGRKVN 435
P + L K R AG+ + SG +E+ + +R Q + + ++
Sbjct: 766 PQQ--------MPPLEKARIAGVGSLPLSGVEEKMFSLLKRAKVQ---LFKIDQQQQQKV 814
Query: 436 FAELPVPPGFPPIPGLESTMGVEEDAVAATLAAAEK--LASAEDSAPADKDEDEPPGHLQ 493
A +P+ PG G E+ A +++ + S ++S A ++ P
Sbjct: 815 AASMPLSPG-----------GQMEEVAGAVKQISDRGPVRSEDESVEAKRERPSGP---- 859
Query: 494 GEPPAQAP----------VAKKPARPTVPSS------------QRLPEPRASSSKESPSP 531
E P Q P VA AR VP Q L SS+ E+ S
Sbjct: 860 -ESPVQGPRIKHVCRHAAVALGQARAMVPEDVPRLSALPLRDRQDLATEDTSSASETESV 918
Query: 532 SVREQLALLEA 542
R + +EA
Sbjct: 919 PSRSRRGKVEA 929
Score = 31.6 bits (70), Expect = 3.3
Identities = 32/150 (21%), Positives = 52/150 (34%), Gaps = 20/150 (13%)
Query: 389 QQRLNKYREAGIQARSGGDERKARMHERIAKQYQDAIRAHRAGRKVNFAELPVPPGFPPI 448
+Q+L+ E + E + + +A++ A A +LP PP PP
Sbjct: 358 EQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEA-------KLPPPPLTPPA 410
Query: 449 PGLESTMGVEEDAVAATLA-------AAEKLASAEDSAPADKDEDEPPGHLQGEPPAQAP 501
P + + L + L S ++ E+ PP P A
Sbjct: 411 PSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPP------PVVPAT 464
Query: 502 VAKKPARPTVPSSQRLPEPRASSSKESPSP 531
++K RP + SQR A + E SP
Sbjct: 465 CSRKRGRPPLTPSQRAEREAARAGPEGTSP 494
Score = 30.8 bits (68), Expect = 5.6
Identities = 31/113 (27%), Positives = 47/113 (41%), Gaps = 9/113 (7%)
Query: 4 GPRPRKGPQARGQGVAAAKQMGLFMEFGPEDMLLGMDEAE---DDEDLEAELLALTGEAQ 60
GPR ++G + RG+G G E D +E + DED+ L +Q
Sbjct: 86 GPRVQRG-RGRGRGRGWGPSRGCVPEEESSDGESDEEEFQGFHSDEDVAPSSLRSALRSQ 144
Query: 61 TTGKKPAPKGQ----APLPMAHIEKLAADCMRDVEEEEEEEGLEEDAELLTEL 109
G+ P +G+ PLP + +A + + EEG E + LTEL
Sbjct: 145 R-GRAPRGRGRKHKTTPLPPPRLADVAPTPPKTPARKRGEEGTERMVQALTEL 196
>gi|148229134 ring finger and KH domain containing 2 [Homo sapiens]
Length = 659
Score = 44.7 bits (104), Expect = 4e-04
Identities = 53/159 (33%), Positives = 72/159 (45%), Gaps = 18/159 (11%)
Query: 38 GMDEAEDDEDLEAELLALTGEAQTTGKKP-APKGQAPLPMAHIE-KLAADCMRDVEEEEE 95
G E E D L E LA G + +P AP +AP A + + AA+ +
Sbjct: 37 GGPELEGDGLLLRERLAALGLDDPSPAEPGAPALRAPAAAAQGQARRAAELSPEERAPPG 96
Query: 96 EEGLEEDAELLTELQEVLGVDEETEPLDGDEVADPGGSEEENGLEDTEPPVQTAVLTASA 155
G E AEL EL+E DEE +G+E G EE LE+ E ++++L S
Sbjct: 97 RPGAPEAAEL--ELEE----DEE----EGEEAELDGDLLEEEELEEAEEEDRSSLLLLSP 146
Query: 156 PAAQAGASQGL------HALLEERIHNYREAAASAKEAG 188
PAA A +Q + LL + REAAA+A AG
Sbjct: 147 PAATASQTQQIPGGSLGSVLLPAARFDAREAAAAAAAAG 185
>gi|226437579 NAC alpha domain containing [Homo sapiens]
Length = 1562
Score = 43.9 bits (102), Expect = 6e-04
Identities = 113/498 (22%), Positives = 179/498 (35%), Gaps = 85/498 (17%)
Query: 60 QTTGKKPAPKGQAPLPMAHIEKLAADC--------MRDVEEEEEEEGL------EEDAEL 105
Q TG P+ PL +A + L A+ + + ++E E L EE
Sbjct: 929 QDTGPTSGPE---PLAVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAA 985
Query: 106 LTELQEVLGVDE--ETEPLDGDEVADPGGSEEENGLEDTEPPVQTAVLTASAPAAQAG-- 161
L + E +D+ + +P E P ++E D + + L+ PA+ AG
Sbjct: 986 LPTVPEPAALDQVQQDDPQPAAEAGTPWAAQE-----DADSTLGMEALSLPEPASGAGEE 1040
Query: 162 -----ASQGLHALLEERIHNYREAAASAKEAGEAAKARRCERGLKTLESQLASVRRGRKI 216
+ G A LE R H A + + + E GLK L + R
Sbjct: 1041 IAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGP--RSALG 1098
Query: 217 NEDEIP--PPVALGK----RPLAPQEP-----ANRSPETDPPAPPALESDNPSQPETSLP 265
E+P PP A + R L+P +PE P+ A E+ S PE+S+
Sbjct: 1099 GAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVG 1158
Query: 266 GISAQPVSDLD-PDPRALLSSRQREYKVAALSAKRAGELDRARELMRIGKRFGAVLEALE 324
+S+ D P P + +S+Q E + S ++ E+ +G E L
Sbjct: 1159 AVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSV-----LGTPLLQPPENLA 1213
Query: 325 KGQPVDLSAMPPAPEDLKPQQASQAPTAPSVIPPAVERVQPVMAPDVPATPVAPTESQTV 384
KGQP P L P ++ A + +PP +E P + D V E
Sbjct: 1214 KGQP-----STPVDRPLGPDPSAPGTLAGAALPP-LEPPAPCLCQDPQEDSVEDEEPPGS 1267
Query: 385 LDALQQRLNKYREAGIQ---ARSGGDERKARMHERIAKQYQDAIRAHRAG---RKVNFAE 438
L +AG+Q A G + R++ + + + K +
Sbjct: 1268 LGLPPP------QAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQ 1321
Query: 439 LPVPPGFPPIPGLESTMG---------------VEEDAVAATLAAAEKLASAEDSAPADK 483
+ P PP G +S G +EED+ A + + E SA D+
Sbjct: 1322 ILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELDE 1381
Query: 484 DEDEPPGHLQGEPPAQAP 501
+ P +Q PAQAP
Sbjct: 1382 QDILAPQTVQ--CPAQAP 1397
>gi|239754540 PREDICTED: NAC alpha domain containing [Homo sapiens]
Length = 1522
Score = 43.9 bits (102), Expect = 6e-04
Identities = 113/498 (22%), Positives = 179/498 (35%), Gaps = 85/498 (17%)
Query: 60 QTTGKKPAPKGQAPLPMAHIEKLAADC--------MRDVEEEEEEEGL------EEDAEL 105
Q TG P+ PL +A + L A+ + + ++E E L EE
Sbjct: 889 QDTGPTSGPE---PLAVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAA 945
Query: 106 LTELQEVLGVDE--ETEPLDGDEVADPGGSEEENGLEDTEPPVQTAVLTASAPAAQAG-- 161
L + E +D+ + +P E P ++E D + + L+ PA+ AG
Sbjct: 946 LPTVPEPAALDQVQQDDPQPAAEAGTPWAAQE-----DADSTLGMEALSLPEPASGAGEE 1000
Query: 162 -----ASQGLHALLEERIHNYREAAASAKEAGEAAKARRCERGLKTLESQLASVRRGRKI 216
+ G A LE R H A + + + E GLK L + R
Sbjct: 1001 IAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGP--RSALG 1058
Query: 217 NEDEIP--PPVALGK----RPLAPQEP-----ANRSPETDPPAPPALESDNPSQPETSLP 265
E+P PP A + R L+P +PE P+ A E+ S PE+S+
Sbjct: 1059 GAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVG 1118
Query: 266 GISAQPVSDLD-PDPRALLSSRQREYKVAALSAKRAGELDRARELMRIGKRFGAVLEALE 324
+S+ D P P + +S+Q E + S ++ E+ +G E L
Sbjct: 1119 AVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSV-----LGTPLLQPPENLA 1173
Query: 325 KGQPVDLSAMPPAPEDLKPQQASQAPTAPSVIPPAVERVQPVMAPDVPATPVAPTESQTV 384
KGQP P L P ++ A + +PP +E P + D V E
Sbjct: 1174 KGQP-----STPVDRPLGPDPSAPGTLAGAALPP-LEPPAPCLCQDPQEDSVEDEEPPGS 1227
Query: 385 LDALQQRLNKYREAGIQ---ARSGGDERKARMHERIAKQYQDAIRAHRAG---RKVNFAE 438
L +AG+Q A G + R++ + + + K +
Sbjct: 1228 LGLPPP------QAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQ 1281
Query: 439 LPVPPGFPPIPGLESTMG---------------VEEDAVAATLAAAEKLASAEDSAPADK 483
+ P PP G +S G +EED+ A + + E SA D+
Sbjct: 1282 ILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELDE 1341
Query: 484 DEDEPPGHLQGEPPAQAP 501
+ P +Q PAQAP
Sbjct: 1342 QDILAPQTVQ--CPAQAP 1357
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 43.9 bits (102), Expect = 6e-04
Identities = 87/346 (25%), Positives = 120/346 (34%), Gaps = 50/346 (14%)
Query: 222 PPPV------------ALGKRPLAPQEPANRS---PETDPPAPPA----LESDNP-SQPE 261
PPPV A+G++PLA + PE+ P A P S NP S+P
Sbjct: 36 PPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPP 95
Query: 262 TSLPGISAQPVSDLDPDPRALLSSRQREYKVAALSAKRAGELDRARELMRIGKRFGAVLE 321
S G A P + P P + + L K G A E + GK A
Sbjct: 96 ASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQK--GLRISAEETVARGKATEAPKR 153
Query: 322 -ALEKGQPVDLSAMPPAPEDLKPQQASQAPTAPSVIPPAVERVQPVMAPDVPATPVAPTE 380
AL G D S P P P A ++ A E P AP A P PTE
Sbjct: 154 SALSAGARRDTSG--PTPGTPSPAMARRSRAA------GTEVGLPRPAPS--ARPRPPTE 203
Query: 381 S--QTVLDALQQRLNKYREAGIQARSGGDERKARMHERIAKQYQDAIRAHRAGRKVNFA- 437
++V A + + A + S G + ++ R+G
Sbjct: 204 GPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTP 263
Query: 438 ELPVPPGFPPIPGLES------TMGVEEDAVAATLAAAEKLASAEDSA-------PADKD 484
P P P GL++ T ++ A A ++ LA+ S P D
Sbjct: 264 RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNA 323
Query: 485 EDEPPGHLQGEPPAQAPVAKKPARPTVPSS-QRLPEPRASSSKESP 529
P L PP P+ P P+ P S Q LP P A+ ++P
Sbjct: 324 ATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAP 369
Score = 36.2 bits (82), Expect = 0.13
Identities = 97/440 (22%), Positives = 150/440 (34%), Gaps = 55/440 (12%)
Query: 124 GDEVADPGGSEEENGLEDTEPPVQ-TAVLTASAPAAQAGASQ-------GLHALLEERIH 175
G +P +G + PP + T+ S+P +G ++ GL EE +
Sbjct: 84 GTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVA 143
Query: 176 NYREAAASAKEAGEAAKARRCERGLKTLESQLASVRRGRKINEDEIPPPVALGKRPLAPQ 235
+ A + K + +A ARR G A RR R + P A RP P
Sbjct: 144 RGK-ATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPT 202
Query: 236 EPANRS------PETDPPAPPALESDNP----SQPETSLPGISAQPVSD---LDPDPRAL 282
E +S T P+P A + +P + SA P+S P R
Sbjct: 203 EGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGT 262
Query: 283 --LSSRQREYKVAALSAKRAGELDRARELMRIGKRFGAVLEA-LEKGQPVDLSAMPPAPE 339
+ + K L A R ++ R+ G + + L P A P P
Sbjct: 263 PRAPAHPSQPKPKGLQALRPPQVTPPRK--DAAPALGPLSSSPLATPSPSGTKARPVPPP 320
Query: 340 DLKPQQASQAPTAPSVIPPAVERVQPVMAPDVPATPVAPTESQTVLDALQQRLNKYREAG 399
D + A P+ +PP+ P+ P P +P AP QT+ A
Sbjct: 321 D------NAATPLPATLPPSPPLATPL--PLAPPSPSAPPSLQTLPSP---------PAT 363
Query: 400 IQARSGGDERKARMHERIAKQYQDAIRAHRAGRKVNFAELPVPPGFPPIPGLESTMGVEE 459
+++ M A I + + L PP + L++T +
Sbjct: 364 PPSQAPPSMTTPPMQ---APPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGS 420
Query: 460 DAVAA-----TLAAAEKLAS-AEDSAPADKDEDEPPGHLQGEPPAQAPV--AKKPARPTV 511
+ A T++ + AS S PA D PP PA P+ + PA +
Sbjct: 421 PTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPL 480
Query: 512 PSSQRLPEPRASSSKESPSP 531
S + +A SS S SP
Sbjct: 481 SSPLTIHPLQALSSLASHSP 500
Score = 35.4 bits (80), Expect = 0.23
Identities = 88/414 (21%), Positives = 134/414 (32%), Gaps = 77/414 (18%)
Query: 144 PPVQTAVLTASAPAAQAGASQGLHALLEE-RIHNYREAAASAKEAGEAAKARRCERGLKT 202
PP+Q + ++P Q S + L IH + ++ A + +A + L+T
Sbjct: 455 PPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLET 514
Query: 203 --------LESQLASVRRGRKINEDEI-PPPVALGKRPLAPQEPANRSPETD-PPAPPAL 252
L++ AS+ N + PPP+ PL +P + PP P
Sbjct: 515 QSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLT-------TPHLETPPCPAPC 567
Query: 253 ESDNPSQPETSLPGISAQPVSDLDPDPRALLSSRQREYKVAALSAKRAGELDRARELMRI 312
P P T+ P + ++ P L+S + + + A +A + +
Sbjct: 568 PLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLAL 627
Query: 313 GKRFGAVLEALEKGQPVDLSAMPPAPEDLKPQQAS-------------QAPTAPSVIPPA 359
P+ PPA L P QAP +P PP
Sbjct: 628 --------------PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPV 673
Query: 360 VERVQPVMAPDVPATPVAPTESQTVLDALQQRLNKYREAGIQARSGGDERKARMHERIAK 419
P +P V + P+++ L A ++ A
Sbjct: 674 QAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS------------------PP 715
Query: 420 QYQDAIRAHRAGRKVNFAELPVPPGFPPIPGLESTMGVEEDAVAATLAAAEKLASAEDSA 479
A +A + L VPP P P + S V LAA
Sbjct: 716 MSPSATPPPQAPPPLAAPPLQVPPSPPASPPM-SPSATPPPRVPPLLAA----------- 763
Query: 480 PADKDEDEPPGHLQGEPPAQAPVAKKPARPTVPSSQRLPEPRASSSKESP-SPS 532
P + PP L P A+ P PA T P Q LP P AS ++P SPS
Sbjct: 764 PPLQVPPSPPASLPMSPLAKPPPQAPPALAT-PPLQALPSPPASFPGQAPFSPS 816
Score = 33.9 bits (76), Expect = 0.66
Identities = 74/312 (23%), Positives = 104/312 (33%), Gaps = 38/312 (12%)
Query: 233 APQEPANRSPETDP-PAPPALESDNPSQPETSLPGISAQPVSDLDPDPRALLSSRQREYK 291
+P PA+ P++ P AP +L + P Q TSL + S L P LSS
Sbjct: 443 SPSRPASTPPDSPPLQAPLSLPASPPLQ--TSLSPAVSPLSSPLTIHPLQALSSLASHSP 500
Query: 292 VAALSAKRAGELDRARELMRIGKRFGAVLEALEKGQPVDLSAMPPAPEDLK-----PQQA 346
A LS+ L+ L A Q S P E+L P Q
Sbjct: 501 QAPLSSLIMPPLETQSSL------------APPSLQTPPASLTTPPLENLPSLAPPPLQT 548
Query: 347 SQAP-TAPSVIPPAVERVQPVMAPDVPATPVAPTESQTVLDALQQRLNKYREAGIQARSG 405
+ AP T P + P P+ AP P T P ++ Q +Q
Sbjct: 549 ASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPS 608
Query: 406 GDERKARMHERIAKQYQDAIRAHRAGRKVNFAELPVPPGFPPIPGLESTMGVEEDAVAAT 465
++ +A P PP PP+ L + +A+A
Sbjct: 609 ---------PPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVH 659
Query: 466 LAAAEKLASAEDSAPAD---KDEDEPPGHLQGEPPAQAP--VAKKPAR-PTVPSSQRLPE 519
L A S S P PP PP+QAP +A P + P P +
Sbjct: 660 LLQAP--FSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS 717
Query: 520 PRASSSKESPSP 531
P A+ ++P P
Sbjct: 718 PSATPPPQAPPP 729
>gi|169205253 PREDICTED: hypothetical protein [Homo sapiens]
Length = 3859
Score = 43.9 bits (102), Expect = 6e-04
Identities = 44/175 (25%), Positives = 64/175 (36%), Gaps = 11/175 (6%)
Query: 219 DEIPPPVALGKRPLAPQEPANRSP-----ETDPPAPPALESDNPSQPETSLPGIS-AQPV 272
D + PV P+ P PA+ SP D P P +D+P P TS S PV
Sbjct: 1672 DGLVVPVTPADSPIVPVTPAD-SPVVLVTSADSPVIPVTPADSPVVPVTSADTDSPGSPV 1730
Query: 273 SDLDPDPRALLSSRQREYKVAALSAKRAGELDRARELMRIGKRFGAVLEALEKGQPVDLS 332
+ D + S+ V + + G V+ PV
Sbjct: 1731 TSADGPVVPVTSADSLPVPVTPADGPVVPVTSADGPVAPVSSADGPVVPVTPADSPV--V 1788
Query: 333 AMPPAPEDLKPQQASQAPTAPSVIPPAVERVQPVMAPDVPATPVAPTESQTVLDA 387
+ A + P + +P P +PPA + PV + D P PV P + VLD+
Sbjct: 1789 PVTTADDPTVPVTPADSPVVP--VPPANGPIVPVTSADSPFVPVIPADGLVVLDS 1841
Score = 39.3 bits (90), Expect = 0.016
Identities = 45/178 (25%), Positives = 64/178 (35%), Gaps = 19/178 (10%)
Query: 224 PVALGKRPLAPQEPANR--SPET------------DPPAPPALESDNPSQPETSLPGISA 269
PV P+ P PA+ SP T D P P D P P TS G A
Sbjct: 1040 PVTAAGDPIVPVTPADTPGSPVTSADGPVVPVTSADSPFVPVTPPDGPVVPVTSADGPVA 1099
Query: 270 QPVSDLDPDPRALLSSRQREYKVAALSAKRAGELDRARELMRIGKRFGAVLEALEKGQPV 329
PVS D + S+ V++ + + ++ PV
Sbjct: 1100 -PVSSADGPVVPVTSADGPVAPVSSADGPVVPVTPADSPFIPVTTADDPIVPVTPADSPV 1158
Query: 330 DLSAMPPAPEDLKPQQASQAPTAPSVIPPAVERVQPVMAPDVPATPVAPTESQTVLDA 387
+ +P + P + +P P +PPA V PV + D P PV P + VLD+
Sbjct: 1159 LSVTLADSP--VVPVTPADSPVIP--VPPANGPVVPVSSADSPFVPVIPADGLVVLDS 1212
Score = 37.0 bits (84), Expect = 0.078
Identities = 43/177 (24%), Positives = 66/177 (37%), Gaps = 27/177 (15%)
Query: 219 DEIPPPVALGKRPLAPQEPANRS--PET--DPPAPPALESDNPSQPETSLPGISAQPVSD 274
D+ PV P+ P PA+ P T D P P +D P P TS + P+
Sbjct: 2202 DDPVVPVTPADSPIVPVPPASDPVVPVTPADTPGSPVASADGPVVPVTS----ADSPLVP 2257
Query: 275 LDPDPRALLSSRQREYKVAALSAKRAGELDRARELMRIGKRFGAVL--EALEKGQPVDLS 332
+ P ++ + V +++ G F L + + P D
Sbjct: 2258 VTPGDSPVVPVTPADSPVFPVTSAD-------------GPVFPVTLADDPVFPVTPADDP 2304
Query: 333 AMPPAPED--LKPQQASQAPTAPSVIPPAVERVQPVMAPDVPATPVAPTESQTVLDA 387
P +P D + P + P P +PPA V PV + P P+ P + VLD+
Sbjct: 2305 IFPVSPADSPVVPVTPANIPVVP--VPPANGSVVPVTSAGSPFVPIIPADGLVVLDS 2359
Score = 36.2 bits (82), Expect = 0.13
Identities = 20/59 (33%), Positives = 29/59 (49%), Gaps = 4/59 (6%)
Query: 328 PVDLSAMP--PAPEDLKPQQASQAPTAPSVIPPAVERVQPVMAPDVPATPVAPTESQTV 384
P D +P PA + + P + +P P +PPA + V PV D P +PVA + V
Sbjct: 2190 PADSPVVPVTPADDPVVPVTPADSPIVP--VPPASDPVVPVTPADTPGSPVASADGPVV 2246
Score = 35.8 bits (81), Expect = 0.17
Identities = 42/169 (24%), Positives = 61/169 (36%), Gaps = 27/169 (15%)
Query: 224 PVALGKRPLAPQEPANRSPETDPPAPPALESDNPSQPETSL--PGISAQPVSDL----DP 277
PV L P+ PAN P P +D P P T P I P DL P
Sbjct: 2067 PVTLVDCPVVSVTPANS------PVDPVTPADGPVVPVTPADSPVIPVTPADDLIVPVTP 2120
Query: 278 DPRALLSSRQREYKVAALSAKRAGELDRARELMRIGKRFGAVLEALEKGQPVDLSAMPPA 337
++S + V ++ + ++ + V+ P D +P
Sbjct: 2121 ADSLIVSVTPADSPVVPVTPADS-------PVISVASADSPVVPVT----PADTVVVPVT 2169
Query: 338 PED--LKPQQASQAPTAPSVIPPAVERVQPVMAPDVPATPVAPTESQTV 384
P D + P +++P P + PA V PV D P PV P +S V
Sbjct: 2170 PADGPVIPVTPAESPAIP--VTPADSPVVPVTPADDPVVPVTPADSPIV 2216
Score = 35.4 bits (80), Expect = 0.23
Identities = 37/164 (22%), Positives = 57/164 (34%), Gaps = 11/164 (6%)
Query: 224 PVALGKRPLAPQEPANRSPETDPPAPPALESDNPSQPETSLPGISAQPVSDLDPDPRALL 283
PV P+ P PA D P P +D P P T PV+ D +
Sbjct: 130 PVTSANGPVIPVTPA------DSPVFPVASADGPVVPVTPADS-PVFPVTPADSPLFPVT 182
Query: 284 SSRQREYKVAALSAKRAGELDRARELMRIGKRFGAVLEALEKGQPVDLSAMPPAPEDLKP 343
+ + V + ++ + G V+ PV A +P + P
Sbjct: 183 PADSPLFPVTPADSAAIPVTPADGPVVHVTPANGTVVPVTPADSPVVTVASTDSP--VVP 240
Query: 344 QQASQAPTAPSVIPPAVERVQPVMAPDVPATPVAPTESQTVLDA 387
+ P P + PA PV++ D P PV P + V+D+
Sbjct: 241 VTPADDPIVP--VTPADSSFVPVISADSPFVPVIPADGPVVVDS 282
Score = 35.0 bits (79), Expect = 0.30
Identities = 41/170 (24%), Positives = 62/170 (36%), Gaps = 11/170 (6%)
Query: 224 PVALGKRPLAPQEPANR--SPET--DPPAPPALESDNPSQPETSLPGISAQPVSDLDPDP 279
PV P+ P PA+ SP T D P P +D+P P T G PV+ D
Sbjct: 699 PVTAAGDPIVPVTPADTPGSPVTSADGPVVPVTSADSPFVPVTPPDG-PVVPVTSADGPV 757
Query: 280 RALLSSRQREYKVAALSAKRAGELDRARELMRI--GKRFGAVLEALEKGQPVDLSAMPPA 337
+ S+ V + A ++ + G + P + PA
Sbjct: 758 APVSSADGPVVPVTSADGPVAPVSSADGPVVPVTPADTNGPAVPVTSADSP--FVPVIPA 815
Query: 338 PEDLKPQQASQAPTAPSVIPPAVERVQPVMAPDVPATPVAPTESQTVLDA 387
+ P + P P + PA PV++ D P PV P + V+D+
Sbjct: 816 DSPVVPVTPADDPIVP--VTPADSSFVPVISADSPFVPVIPADGPVVVDS 863
Score = 35.0 bits (79), Expect = 0.30
Identities = 44/176 (25%), Positives = 64/176 (36%), Gaps = 21/176 (11%)
Query: 224 PVALGKRPLAPQEPANRS----PETDPPAPPALESDNPSQPETSL--PGISAQPVSD--- 274
PV P+ P PA+ D P P +D+P P T P +S P
Sbjct: 1308 PVTSADSPVVPVTPADGPVVPVTSADSPFVPVTPADDPIVPVTPADSPIVSVTPAESPAI 1367
Query: 275 -LDPDPRALLSSRQREYKVAALSAKRAGELDRARELMRIGKRFGAVLEALEKGQPVDLSA 333
+ P ++ + + L+ AG R + G V A G PV +
Sbjct: 1368 PVTPADSPVVPVTSADSPLIPLTT--AGS--RVVPVTPTGDPIVPVTPADTPGSPVTSAD 1423
Query: 334 MP-----PAPEDLKPQQASQAPTAPSVIPPAVERVQPVMAPDVPATPVAPTESQTV 384
P PA + + P + P +P + A V PV PD P PV+P + V
Sbjct: 1424 GPVVPVTPAGDPIVPVTPADTPGSP--VTSADGPVVPVTTPDGPLVPVSPPDGPVV 1477
Score = 34.7 bits (78), Expect = 0.39
Identities = 41/173 (23%), Positives = 62/173 (35%), Gaps = 23/173 (13%)
Query: 224 PVALGKRPLAPQEPANRSPE-----TDPPAPPALESDNPSQPETS-----LPGISAQ--- 270
PV P+ P PA+ SP D PA P +D+P P T +P SA
Sbjct: 589 PVTPADSPVVPVTPAD-SPVLSVTLADSPAVPVTPADSPVVPVTPADGPVVPVASADSPF 647
Query: 271 -PVSDLDPDPRALLSSRQREYKVAALSAKRAGELDRARELMRIGKRFGAVLEALEKGQPV 329
PV+ D ++ + V + R ++ + G ++ G P+
Sbjct: 648 VPVTPADDPIVSVTPAESPAIPVTQADSPVVPVTSADRPVIPVTTADGRIVPVTAAGDPI 707
Query: 330 DLSAMPPAPEDL--KPQQASQAPTAPSVIPPAVERVQPVMAPDVPATPVAPTE 380
+P P D P ++ P P + A PV PD P PV +
Sbjct: 708 ----VPVTPADTPGSPVTSADGPVVP--VTSADSPFVPVTPPDGPVVPVTSAD 754
Score = 34.3 bits (77), Expect = 0.51
Identities = 39/161 (24%), Positives = 52/161 (32%), Gaps = 21/161 (13%)
Query: 224 PVALGKRPLAPQEPANRSPETDPPAPPALESDNPSQPETSLPGISAQPVSDLDPDPRALL 283
PV P+ P PA D P P +D P P T G PV+ D +
Sbjct: 1398 PVTPTGDPIVPVTPA------DTPGSPVTSADGPVVPVTPA-GDPIVPVTPADTPGSPVT 1450
Query: 284 SSRQREYKVAALSAKRAGELDRARELMRIGKRFGAVLEALEKGQPVDLSAMPPAPEDLKP 343
S+ V L+ + G V+ PV + PA P
Sbjct: 1451 SADGPVVPVTTPDGP----------LVPVSPPDGPVVPVTSADGPV--VPVTPADSPFIP 1498
Query: 344 QQASQAPTAPSVIPPAVERVQPVMAPDVPATPVAPTESQTV 384
+ P P + PA V PV D+P PV P +
Sbjct: 1499 VTTADDPIVP--VTPADSPVVPVTPADIPVVPVTPANGPVI 1537
Score = 33.9 bits (76), Expect = 0.66
Identities = 41/173 (23%), Positives = 59/173 (34%), Gaps = 47/173 (27%)
Query: 225 VALGKRPLAPQEPANRSP-----ETDPPAPPALESDNPSQPETSL--PGISAQPVSD--- 274
V + P+ P PA+ SP D P P DNP P T P I PV D
Sbjct: 1869 VTIADSPVIPVTPAD-SPVVLVTPADGPVVPVTSVDNPVVPVTPADNPVIPVTPVDDPVV 1927
Query: 275 -LDPDPRALLSSRQREYKVAALSAKRAGELDRARELMRIGKRFGAVLEALEKGQPVDLSA 333
+ P ++ + + +++ P D
Sbjct: 1928 PVTPADDPIVPVTSADSPIVSVT-------------------------------PADSPV 1956
Query: 334 MPPAPED--LKPQQASQAPTAPSVIPPAVERVQPVMAPDVPATPVAPTESQTV 384
P P D + P ++ +P P + PA V PV+ D P PV P ES +
Sbjct: 1957 FPVTPADSPVIPVASADSPLVP--VTPADMVVVPVIPADGPVIPVTPAESPAI 2007
Score = 33.1 bits (74), Expect = 1.1
Identities = 40/171 (23%), Positives = 62/171 (36%), Gaps = 33/171 (19%)
Query: 225 VALGKRPLAPQEPANRSP-----ETDPPAPPALESDNPSQPETSLPG------ISAQPVS 273
V L P+ P PA+ SP D P P +D+P P T G + P
Sbjct: 340 VTLADSPVVPVTPAD-SPFVPAIPADGPVVPVTPADSPVVPVTPADGPVVSVASADSPFV 398
Query: 274 DLDPDPRALLSSRQREYKVAALSAKRAGELDRARELMRIGKRFGAVLEALEKGQPVDLSA 333
+ P ++S + V +++ + L+ + G V+ G P+
Sbjct: 399 PVTPADDPIVSVTPADSPVVPVTSADS-------PLIPVTTADGRVVPVTAAGDPI---- 447
Query: 334 MPPAPEDLKPQQASQAPTAPSVIPPAVERVQPVMAPDVPATPVAPTESQTV 384
+P P D T S + A V PV + D+P PV P + V
Sbjct: 448 VPVTPAD----------TPGSPVTSADGPVVPVTSADIPLVPVTPPDGPVV 488
Score = 33.1 bits (74), Expect = 1.1
Identities = 36/161 (22%), Positives = 57/161 (35%), Gaps = 31/161 (19%)
Query: 224 PVALGKRPLAPQEPANRSPETDPPAPPALESDNPSQPETSLPGISAQPVSDLDPDPRALL 283
PV P+ P PA D P P +D+P P T + P+ + P +
Sbjct: 619 PVTPADSPVVPVTPA------DGPVVPVASADSPFVPVTP----ADDPIVSVTPAESPAI 668
Query: 284 SSRQREYKVAALSAKRAGELDRARELMRIGKRFGAVLEALEKGQPVDLSAMPPAPEDLKP 343
Q + V +++ R ++ + G ++ G P+ +P P D
Sbjct: 669 PVTQADSPVVPVTSAD-------RPVIPVTTADGRIVPVTAAGDPI----VPVTPAD--- 714
Query: 344 QQASQAPTAPSVIPPAVERVQPVMAPDVPATPVAPTESQTV 384
T S + A V PV + D P PV P + V
Sbjct: 715 -------TPGSPVTSADGPVVPVTSADSPFVPVTPPDGPVV 748
Score = 33.1 bits (74), Expect = 1.1
Identities = 21/60 (35%), Positives = 29/60 (48%), Gaps = 4/60 (6%)
Query: 328 PVD--LSAMPPAPEDLKPQQASQAPTAPSVIPPAVERVQPVMAPDVPATPVAPTESQTVL 385
PVD + ++ PA + P ++ P P + PA V PV D P PV P +S VL
Sbjct: 1640 PVDDPVVSVNPADGSVVPVTSADCPVVP--VTPADGLVVPVTPADSPIVPVTPADSPVVL 1697
Score = 33.1 bits (74), Expect = 1.1
Identities = 19/52 (36%), Positives = 24/52 (46%), Gaps = 2/52 (3%)
Query: 337 APEDLKPQQASQAPTAPSVIPPAVERVQPVMAPDVPATPVAPTESQTVLDAL 388
A + P ++ P P + A V P APD P PV PT+ VLD L
Sbjct: 3562 ADVSILPDTSADVPVTPVTL--ADGSVVPDSAPDCPVVPVLPTDGFVVLDLL 3611
Score = 32.3 bits (72), Expect = 1.9
Identities = 37/161 (22%), Positives = 57/161 (35%), Gaps = 21/161 (13%)
Query: 224 PVALGKRPLAPQEPANRSPETDPPAPPALESDNPSQPETSLPGISAQPVSDLDPDPRALL 283
PV P+AP A D P P +D+P P T+ + PV+ D ++
Sbjct: 489 PVTSADGPVAPVSSA------DGPVVPVTPADSPFIPVTTADDLIV-PVTPADSPVLSVT 541
Query: 284 SSRQREYKVAALSAKRAGELDRARELMRIGKRFGAVLEALEKGQPVDLSAMPPAPEDLKP 343
+ V + ++ + G V+ P + PA + P
Sbjct: 542 PAESPAIPVTPADSP----------IVPVTPANGPVVPVTSADSP--FVPVIPADGPVVP 589
Query: 344 QQASQAPTAPSVIPPAVERVQPVMAPDVPATPVAPTESQTV 384
+ +P P + PA V V D PA PV P +S V
Sbjct: 590 VTPADSPVVP--VTPADSPVLSVTLADSPAVPVTPADSPVV 628
Score = 32.3 bits (72), Expect = 1.9
Identities = 44/167 (26%), Positives = 65/167 (38%), Gaps = 24/167 (14%)
Query: 224 PVALGKRPLAPQEPANRSPETDPPAPPALESDNPSQPETSLPGISAQPVSDLDPDPRALL 283
PV L P+ P PA D P P +D+P P T I PV + +
Sbjct: 2287 PVTLADDPVFPVTPA------DDPIFPVSPADSPVVPVTPA-NIPVVPVPPANGSVVPVT 2339
Query: 284 SSRQREYKVAALSAKRAGELDRARELMRIGKRFGAVLEALEKGQPV-DLSAMP-----PA 337
S+ V + A LD + +++ VL + G PV DL+ P +
Sbjct: 2340 SAGSPF--VPIIPADGLVVLDSSTDVL-------VVLVSPTDGIPVPDLADDPVVSVTTS 2390
Query: 338 PEDLKPQQASQAPTAPSVIPPAVERVQPVMAPDVPATPVAPTESQTV 384
+ P + +P P + PA V PV + D P PV P +S +
Sbjct: 2391 DSPVIPVTPTDSPVVP--VAPADGPVVPVTSVDSPVVPVTPADSPVI 2435
Score = 32.3 bits (72), Expect = 1.9
Identities = 20/56 (35%), Positives = 25/56 (44%), Gaps = 4/56 (7%)
Query: 328 PVDLSAMP--PAPEDLKPQQASQAPTAPSVIPPAVERVQPVMAPDVPATPVAPTES 381
P D S +P PA + P P P + PA V PV + D P PV P +S
Sbjct: 2549 PADSSVVPVTPAGVPVVPVTPGDGPVVP--VTPADSLVVPVTSADSPVFPVTPADS 2602
Score = 32.0 bits (71), Expect = 2.5
Identities = 40/167 (23%), Positives = 57/167 (34%), Gaps = 9/167 (5%)
Query: 224 PVALGKRPLAPQEPANRS----PETDPPAPPALESDNPSQPETSLPGISAQPVSDLDPDP 279
PV P P P + D P P +D P P TS G A PVS D
Sbjct: 1070 PVTSADSPFVPVTPPDGPVVPVTSADGPVAPVSSADGPVVPVTSADGPVA-PVSSADGPV 1128
Query: 280 RALLSSRQREYKVAALSAKRAGELDRARELMRIGKRFGAVLEALEKGQPVDLSAMPPAPE 339
+ + V ++ + V+ PV +PPA
Sbjct: 1129 VPVTPADSPFIPVTTADDPIVPVTPADSPVLSVTLADSPVVPVTPADSPV--IPVPPANG 1186
Query: 340 DLKPQQASQAPTAPSVIPPAVERVQPVMAPDVPATPVAPTESQTVLD 386
+ P ++ +P P + PA V + DV PV+PT+ V D
Sbjct: 1187 PVVPVSSADSPFVPVI--PADGLVVLDSSTDVLVVPVSPTDGILVPD 1231
Score = 32.0 bits (71), Expect = 2.5
Identities = 41/168 (24%), Positives = 60/168 (35%), Gaps = 34/168 (20%)
Query: 224 PVALGKRPLAPQEPANRSPE-----TDPPAPPALESDNPSQPETSLPGISAQPVSDLDPD 278
PV P+ P PA+ SP D P P +D+P P G PVS D
Sbjct: 1140 PVTTADDPIVPVTPAD-SPVLSVTLADSPVVPVTPADSPVIPVPPANG-PVVPVSSADSP 1197
Query: 279 PRALLSSRQREYKVAALSAKRAGELDRARELMRIGKRFGAVLEALEKGQPVDLSAMPPAP 338
V + A LD + +++ + P D +P
Sbjct: 1198 ------------FVPVIPADGLVVLDSSTDVLVVPV------------SPTDGILVPDLA 1233
Query: 339 ED-LKPQQASQAPTAPSVIPPAVERVQPVMAPDVPATPVAPTESQTVL 385
+D + + +P P + PA V PV + D P PV P +S +L
Sbjct: 1234 DDPVVSVTIADSPVIP--VTPADSPVVPVTSADSPVVPVTPADSPVIL 1279
Score = 32.0 bits (71), Expect = 2.5
Identities = 41/161 (25%), Positives = 60/161 (37%), Gaps = 26/161 (16%)
Query: 232 LAPQEPANRSPETDPPAP----PALESDNPSQPETSLPGISAQPVSDLDPDPRALLSSRQ 287
L P PA+ S D PA P +D P P+ S+ G PV + P +S
Sbjct: 3235 LVPVTPADDSVVPDSPANGLVVPDPTTDGPVAPDPSVDG----PVVPVTPADAPTVSVTL 3290
Query: 288 REYKVAALSAKRAGELDRARELMRIGKRFGAVLEALEKGQPVDLSAMPPAPEDLKPQQAS 347
+ ++ ++ KR G V+ L PV ++A P D+ +
Sbjct: 3291 ADCPDVTVTPPDG-------LVVSDSKRGGPVVTGLSTNDPV-ITATPADFSDV-----T 3337
Query: 348 QAPTAPSVIPPAVERVQPVMAPDVPATPVAPTESQTVLDAL 388
P +P V P PDVP P +P S +D L
Sbjct: 3338 VTPADFEDVP-----VTPANCPDVPVNPESPVVSDLAVDFL 3373
Score = 31.6 bits (70), Expect = 3.3
Identities = 20/60 (33%), Positives = 28/60 (46%), Gaps = 4/60 (6%)
Query: 328 PVDLSAMPPAPED--LKPQQASQAPTAPSVIPPAVERVQPVMAPDVPATPVAPTESQTVL 385
P D +P D + P + +P P + PA + V PV D P PV+P +S VL
Sbjct: 2579 PADSLVVPVTSADSPVFPVTPADSPVFP--VSPADDLVVPVTPGDSPVVPVSPADSPVVL 2636
Score = 31.6 bits (70), Expect = 3.3
Identities = 19/60 (31%), Positives = 26/60 (43%)
Query: 328 PVDLSAMPPAPEDLKPQQASQAPTAPSVIPPAVERVQPVMAPDVPATPVAPTESQTVLDA 387
P D +P +P D + A + PA V PV + D P PV P + VLD+
Sbjct: 2619 PGDSPVVPVSPADSPVVLVTPADGPVVPVTPANGPVVPVTSADSPFVPVIPADGLVVLDS 2678
Score = 30.4 bits (67), Expect = 7.3
Identities = 16/46 (34%), Positives = 22/46 (47%), Gaps = 2/46 (4%)
Query: 336 PAPEDLKPQQASQAPTAPSVIPPAVERVQPVMAPDVPATPVAPTES 381
PA + P ++ P P + PA V PV + D P PV P +S
Sbjct: 123 PADNPVVPVTSANGPVIP--VTPADSPVFPVASADGPVVPVTPADS 166
>gi|239749105 PREDICTED: NAC alpha domain containing [Homo sapiens]
Length = 1522
Score = 43.9 bits (102), Expect = 6e-04
Identities = 113/498 (22%), Positives = 179/498 (35%), Gaps = 85/498 (17%)
Query: 60 QTTGKKPAPKGQAPLPMAHIEKLAADC--------MRDVEEEEEEEGL------EEDAEL 105
Q TG P+ PL +A + L A+ + + ++E E L EE
Sbjct: 889 QDTGPTSGPE---PLAVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAA 945
Query: 106 LTELQEVLGVDE--ETEPLDGDEVADPGGSEEENGLEDTEPPVQTAVLTASAPAAQAG-- 161
L + E +D+ + +P E P ++E D + + L+ PA+ AG
Sbjct: 946 LPTVPEPAALDQVQQDDPQPAAEAGTPWAAQE-----DADSTLGMEALSLPEPASGAGEE 1000
Query: 162 -----ASQGLHALLEERIHNYREAAASAKEAGEAAKARRCERGLKTLESQLASVRRGRKI 216
+ G A LE R H A + + + E GLK L + R
Sbjct: 1001 IAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGP--RSALG 1058
Query: 217 NEDEIP--PPVALGK----RPLAPQEP-----ANRSPETDPPAPPALESDNPSQPETSLP 265
E+P PP A + R L+P +PE P+ A E+ S PE+S+
Sbjct: 1059 GAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVG 1118
Query: 266 GISAQPVSDLD-PDPRALLSSRQREYKVAALSAKRAGELDRARELMRIGKRFGAVLEALE 324
+S+ D P P + +S+Q E + S ++ E+ +G E L
Sbjct: 1119 AVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSV-----LGTPLLQPPENLA 1173
Query: 325 KGQPVDLSAMPPAPEDLKPQQASQAPTAPSVIPPAVERVQPVMAPDVPATPVAPTESQTV 384
KGQP P L P ++ A + +PP +E P + D V E
Sbjct: 1174 KGQP-----STPVDRPLGPDPSAPGTLAGAALPP-LEPPAPCLCQDPQEDSVEDEEPPGS 1227
Query: 385 LDALQQRLNKYREAGIQ---ARSGGDERKARMHERIAKQYQDAIRAHRAG---RKVNFAE 438
L +AG+Q A G + R++ + + + K +
Sbjct: 1228 LGLPPP------QAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQ 1281
Query: 439 LPVPPGFPPIPGLESTMG---------------VEEDAVAATLAAAEKLASAEDSAPADK 483
+ P PP G +S G +EED+ A + + E SA D+
Sbjct: 1282 ILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELDE 1341
Query: 484 DEDEPPGHLQGEPPAQAP 501
+ P +Q PAQAP
Sbjct: 1342 QDILAPQTVQ--CPAQAP 1357
>gi|239743134 PREDICTED: NAC alpha domain containing [Homo sapiens]
Length = 1562
Score = 43.9 bits (102), Expect = 6e-04
Identities = 113/498 (22%), Positives = 179/498 (35%), Gaps = 85/498 (17%)
Query: 60 QTTGKKPAPKGQAPLPMAHIEKLAADC--------MRDVEEEEEEEGL------EEDAEL 105
Q TG P+ PL +A + L A+ + + ++E E L EE
Sbjct: 929 QDTGPTSGPE---PLAVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAA 985
Query: 106 LTELQEVLGVDE--ETEPLDGDEVADPGGSEEENGLEDTEPPVQTAVLTASAPAAQAG-- 161
L + E +D+ + +P E P ++E D + + L+ PA+ AG
Sbjct: 986 LPTVPEPAALDQVQQDDPQPAAEAGTPWAAQE-----DADSTLGMEALSLPEPASGAGEE 1040
Query: 162 -----ASQGLHALLEERIHNYREAAASAKEAGEAAKARRCERGLKTLESQLASVRRGRKI 216
+ G A LE R H A + + + E GLK L + R
Sbjct: 1041 IAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGP--RSALG 1098
Query: 217 NEDEIP--PPVALGK----RPLAPQEP-----ANRSPETDPPAPPALESDNPSQPETSLP 265
E+P PP A + R L+P +PE P+ A E+ S PE+S+
Sbjct: 1099 GAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVG 1158
Query: 266 GISAQPVSDLD-PDPRALLSSRQREYKVAALSAKRAGELDRARELMRIGKRFGAVLEALE 324
+S+ D P P + +S+Q E + S ++ E+ +G E L
Sbjct: 1159 AVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSV-----LGTPLLQPPENLA 1213
Query: 325 KGQPVDLSAMPPAPEDLKPQQASQAPTAPSVIPPAVERVQPVMAPDVPATPVAPTESQTV 384
KGQP P L P ++ A + +PP +E P + D V E
Sbjct: 1214 KGQP-----STPVDRPLGPDPSAPGTLAGAALPP-LEPPAPCLCQDPQEDSVEDEEPPGS 1267
Query: 385 LDALQQRLNKYREAGIQ---ARSGGDERKARMHERIAKQYQDAIRAHRAG---RKVNFAE 438
L +AG+Q A G + R++ + + + K +
Sbjct: 1268 LGLPPP------QAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQ 1321
Query: 439 LPVPPGFPPIPGLESTMG---------------VEEDAVAATLAAAEKLASAEDSAPADK 483
+ P PP G +S G +EED+ A + + E SA D+
Sbjct: 1322 ILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELDE 1381
Query: 484 DEDEPPGHLQGEPPAQAP 501
+ P +Q PAQAP
Sbjct: 1382 QDILAPQTVQ--CPAQAP 1397
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.130 0.365
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,798,218
Number of Sequences: 37866
Number of extensions: 2093282
Number of successful extensions: 20131
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 119
Number of HSP's successfully gapped in prelim test: 915
Number of HSP's that attempted gapping in prelim test: 14474
Number of HSP's gapped (non-prelim): 5474
length of query: 858
length of database: 18,247,518
effective HSP length: 111
effective length of query: 747
effective length of database: 14,044,392
effective search space: 10491160824
effective search space used: 10491160824
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.