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Search of human proteins with 61742136
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|61742136 F-box and leucine-rich repeat protein 6 isoform 2
[Homo sapiens]
(533 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|61742136 F-box and leucine-rich repeat protein 6 isoform 2 [H... 1084 0.0
gi|16306576 F-box and leucine-rich repeat protein 6 isoform 1 [H... 1077 0.0
gi|6912466 F-box and leucine-rich repeat protein 7 [Homo sapiens] 76 7e-14
gi|16306588 F-box and leucine-rich repeat protein 4 [Homo sapiens] 67 5e-11
gi|22748931 F-box and leucine-rich repeat protein 14 [Homo sapiens] 64 4e-10
gi|27734755 F-box and leucine-rich repeat protein 20 [Homo sapiens] 60 5e-09
gi|16306582 F-box and leucine-rich repeat protein 2 [Homo sapiens] 59 1e-08
gi|161333854 F-box and leucine-rich repeat protein 13 isoform 2 ... 50 7e-06
gi|161333852 F-box and leucine-rich repeat protein 13 isoform 1 ... 49 9e-06
gi|16306595 S-phase kinase-associated protein 2 isoform 1 [Homo ... 47 6e-05
gi|14249170 S-phase kinase-associated protein 2 isoform 2 [Homo ... 47 6e-05
gi|24025682 F-box and leucine-rich repeat protein 16 [Homo sapiens] 47 6e-05
gi|22547146 F-box and leucine-rich repeat protein 8 [Homo sapiens] 45 1e-04
gi|117938759 GNAS complex locus XLas [Homo sapiens] 45 2e-04
gi|190194416 F-box and leucine-rich repeat protein 15 [Homo sapi... 44 3e-04
gi|157168349 F-box and leucine-rich repeat protein 19 [Homo sapi... 43 6e-04
gi|116268109 nucleotide-binding oligomerization domains 27 [Homo... 42 0.001
gi|54112382 F-box and leucine-rich repeat protein 10 isoform a [... 41 0.003
gi|54112380 F-box and leucine-rich repeat protein 10 isoform b [... 41 0.003
gi|24308207 leucine rich repeat containing 47 [Homo sapiens] 41 0.003
gi|239750101 PREDICTED: hypothetical protein [Homo sapiens] 40 0.004
gi|18699730 solute carrier family 16, member 10 [Homo sapiens] 40 0.004
gi|30520327 F-box protein 27 [Homo sapiens] 40 0.004
gi|113416879 PREDICTED: hypothetical protein [Homo sapiens] 40 0.005
gi|4505101 microtubule-associated protein 7 [Homo sapiens] 40 0.005
gi|110832843 TBP-associated factor 4 [Homo sapiens] 40 0.007
gi|149158690 HLA-B associated transcript-2 [Homo sapiens] 40 0.007
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [... 40 0.007
gi|30089926 F-box only protein 11 isoform 1 [Homo sapiens] 40 0.007
gi|30089924 F-box only protein 11 isoform 2 [Homo sapiens] 40 0.007
>gi|61742136 F-box and leucine-rich repeat protein 6 isoform 2 [Homo
sapiens]
Length = 533
Score = 1084 bits (2803), Expect = 0.0
Identities = 533/533 (100%), Positives = 533/533 (100%)
Query: 1 MAAPASRQVRRRARAAPRPRSAEDWWWDRLAPRGSGYHLLQSDSMLLVLSEPGPARPRAQ 60
MAAPASRQVRRRARAAPRPRSAEDWWWDRLAPRGSGYHLLQSDSMLLVLSEPGPARPRAQ
Sbjct: 1 MAAPASRQVRRRARAAPRPRSAEDWWWDRLAPRGSGYHLLQSDSMLLVLSEPGPARPRAQ 60
Query: 61 RRASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAPTPTPEEGPDAGWGDRIPLEIL 120
RRASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAPTPTPEEGPDAGWGDRIPLEIL
Sbjct: 61 RRASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAPTPTPEEGPDAGWGDRIPLEIL 120
Query: 121 VQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWHTVTLSSPLVGRPAKGGVKAEKK 180
VQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWHTVTLSSPLVGRPAKGGVKAEKK
Sbjct: 121 VQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWHTVTLSSPLVGRPAKGGVKAEKK 180
Query: 181 LLASLEWLMPNRFSQLQRLTLIHWKSQLVGECCPRLTFLKLSGCHGVTADALVMLAKACC 240
LLASLEWLMPNRFSQLQRLTLIHWKSQLVGECCPRLTFLKLSGCHGVTADALVMLAKACC
Sbjct: 181 LLASLEWLMPNRFSQLQRLTLIHWKSQLVGECCPRLTFLKLSGCHGVTADALVMLAKACC 240
Query: 241 QLHSLDLQHSMVESTAVVSFLEEAGSRMRKLWLTYSSQTTAILGALLGSCCPQLQVLEVS 300
QLHSLDLQHSMVESTAVVSFLEEAGSRMRKLWLTYSSQTTAILGALLGSCCPQLQVLEVS
Sbjct: 241 QLHSLDLQHSMVESTAVVSFLEEAGSRMRKLWLTYSSQTTAILGALLGSCCPQLQVLEVS 300
Query: 301 TGINRNSIPLQLPVEALQKGCPQLQVLRLLNLMWLPKPPGRGVAPGPGFPSLEELCLASS 360
TGINRNSIPLQLPVEALQKGCPQLQVLRLLNLMWLPKPPGRGVAPGPGFPSLEELCLASS
Sbjct: 301 TGINRNSIPLQLPVEALQKGCPQLQVLRLLNLMWLPKPPGRGVAPGPGFPSLEELCLASS 360
Query: 361 TCNFVSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDLPCRELEQLHLGLYGTSDRLTL 420
TCNFVSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDLPCRELEQLHLGLYGTSDRLTL
Sbjct: 361 TCNFVSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDLPCRELEQLHLGLYGTSDRLTL 420
Query: 421 AKEGSPFLTQKWCHTLRELDLSGQGFSEKDLEQALAAFLSTPGGSHPALCSLNLRGTRVT 480
AKEGSPFLTQKWCHTLRELDLSGQGFSEKDLEQALAAFLSTPGGSHPALCSLNLRGTRVT
Sbjct: 421 AKEGSPFLTQKWCHTLRELDLSGQGFSEKDLEQALAAFLSTPGGSHPALCSLNLRGTRVT 480
Query: 481 PSTVSSVISSCPGLLYLNLESCRCLPRGLKRAYRGLEEVQWCLEQLLTSPSPS 533
PSTVSSVISSCPGLLYLNLESCRCLPRGLKRAYRGLEEVQWCLEQLLTSPSPS
Sbjct: 481 PSTVSSVISSCPGLLYLNLESCRCLPRGLKRAYRGLEEVQWCLEQLLTSPSPS 533
>gi|16306576 F-box and leucine-rich repeat protein 6 isoform 1 [Homo
sapiens]
Length = 539
Score = 1077 bits (2786), Expect = 0.0
Identities = 533/539 (98%), Positives = 533/539 (98%), Gaps = 6/539 (1%)
Query: 1 MAAPASRQVRRRARAAPRPRSAEDWWWDRLAPRGSGYHLLQSDSMLLVLSEPGPARPRAQ 60
MAAPASRQVRRRARAAPRPRSAEDWWWDRLAPRGSGYHLLQSDSMLLVLSEPGPARPRAQ
Sbjct: 1 MAAPASRQVRRRARAAPRPRSAEDWWWDRLAPRGSGYHLLQSDSMLLVLSEPGPARPRAQ 60
Query: 61 RRASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAPTPTPEEGPDAGWGDRIPLEIL 120
RRASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAPTPTPEEGPDAGWGDRIPLEIL
Sbjct: 61 RRASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAPTPTPEEGPDAGWGDRIPLEIL 120
Query: 121 VQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWHTVTLSSPLVGRPAKGGVKAEKK 180
VQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWHTVTLSSPLVGRPAKGGVKAEKK
Sbjct: 121 VQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWHTVTLSSPLVGRPAKGGVKAEKK 180
Query: 181 LLASLEWLMPNRFSQLQRLTLIHWKSQ------LVGECCPRLTFLKLSGCHGVTADALVM 234
LLASLEWLMPNRFSQLQRLTLIHWKSQ LVGECCPRLTFLKLSGCHGVTADALVM
Sbjct: 181 LLASLEWLMPNRFSQLQRLTLIHWKSQVHPVLKLVGECCPRLTFLKLSGCHGVTADALVM 240
Query: 235 LAKACCQLHSLDLQHSMVESTAVVSFLEEAGSRMRKLWLTYSSQTTAILGALLGSCCPQL 294
LAKACCQLHSLDLQHSMVESTAVVSFLEEAGSRMRKLWLTYSSQTTAILGALLGSCCPQL
Sbjct: 241 LAKACCQLHSLDLQHSMVESTAVVSFLEEAGSRMRKLWLTYSSQTTAILGALLGSCCPQL 300
Query: 295 QVLEVSTGINRNSIPLQLPVEALQKGCPQLQVLRLLNLMWLPKPPGRGVAPGPGFPSLEE 354
QVLEVSTGINRNSIPLQLPVEALQKGCPQLQVLRLLNLMWLPKPPGRGVAPGPGFPSLEE
Sbjct: 301 QVLEVSTGINRNSIPLQLPVEALQKGCPQLQVLRLLNLMWLPKPPGRGVAPGPGFPSLEE 360
Query: 355 LCLASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDLPCRELEQLHLGLYGT 414
LCLASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDLPCRELEQLHLGLYGT
Sbjct: 361 LCLASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDLPCRELEQLHLGLYGT 420
Query: 415 SDRLTLAKEGSPFLTQKWCHTLRELDLSGQGFSEKDLEQALAAFLSTPGGSHPALCSLNL 474
SDRLTLAKEGSPFLTQKWCHTLRELDLSGQGFSEKDLEQALAAFLSTPGGSHPALCSLNL
Sbjct: 421 SDRLTLAKEGSPFLTQKWCHTLRELDLSGQGFSEKDLEQALAAFLSTPGGSHPALCSLNL 480
Query: 475 RGTRVTPSTVSSVISSCPGLLYLNLESCRCLPRGLKRAYRGLEEVQWCLEQLLTSPSPS 533
RGTRVTPSTVSSVISSCPGLLYLNLESCRCLPRGLKRAYRGLEEVQWCLEQLLTSPSPS
Sbjct: 481 RGTRVTPSTVSSVISSCPGLLYLNLESCRCLPRGLKRAYRGLEEVQWCLEQLLTSPSPS 539
>gi|6912466 F-box and leucine-rich repeat protein 7 [Homo sapiens]
Length = 491
Score = 76.3 bits (186), Expect = 7e-14
Identities = 105/418 (25%), Positives = 163/418 (38%), Gaps = 80/418 (19%)
Query: 113 DRIPLEILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWHTVTLSSPLVGRPAK 172
DR+P +VQIF L P L R ARVCRRW A P LW T+ L+ +
Sbjct: 115 DRLPDHSMVQIFSFL-----PTNQLCRCARVCRRWYNLAWDPRLWRTIRLTGETINVD-- 167
Query: 173 GGVKAEKKLLASLEWLMPNRFSQLQRLTLIHWKS------QLVGECCPRLTFLKLSGCHG 226
+A K L L PN L+ +T+ + + +CCP L L++SGC+
Sbjct: 168 ---RALKVLTRRLCQDTPNVCLMLETVTVSGCRRLTDRGLYTIAQCCPELRRLEVSGCYN 224
Query: 227 VTADALVMLAKACCQLHSLDLQHSMVESTAVVSFLEEAGSRM-----RKLWLTYSSQTTA 281
++ +A+ + C L LD+ S +S EA ++ +++ + Y T
Sbjct: 225 ISNEAVFDVVSLCPNLEHLDV--SGCSKVTCISLTREASIKLSPLHGKQISIRYLDMTDC 282
Query: 282 ILGALLGSCCPQLQVLEVSTGINRNSIPLQLPVEALQKGCPQLQVLRLLNLMWLPKPPGR 341
VLE G++ + C QL L L + L R
Sbjct: 283 F-------------VLE-DEGLH-----------TIAAHCTQLTHLYLRRCVRLTDEGLR 317
Query: 342 GVAPGPGFPSLEELCLASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDLP- 400
+ S++EL + S C FVS+ L + LR L + C R+T G++ +
Sbjct: 318 YLV--IYCASIKELSV--SDCRFVSDFGLREIAKLESRLRYLSIAHCGRVTDVGIRYVAK 373
Query: 401 -CRELEQLHL-GLYGTSDRLTLAKEGSPFLTQKWCHTLRELDLSGQGFSEKDLEQALAAF 458
C +L L+ G G +D G +L K C L+ LD+
Sbjct: 374 YCSKLRYLNARGCEGITD------HGVEYLA-KNCTKLKSLDI------------GKCPL 414
Query: 459 LSTPGGSHPALCSLNLRG------TRVTPSTVSSVISSCPGLLYLNLESCRCLPRGLK 510
+S G AL NL+ +T + V ++C L LN++ C L+
Sbjct: 415 VSDTGLECLALNCFNLKRLSLKSCESITGQGLQIVAANCFDLQTLNVQDCEVSVEALR 472
>gi|16306588 F-box and leucine-rich repeat protein 4 [Homo sapiens]
Length = 621
Score = 66.6 bits (161), Expect = 5e-11
Identities = 84/353 (23%), Positives = 144/353 (40%), Gaps = 45/353 (12%)
Query: 105 EGPDAGWGDRIPLEILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWHTVTLSS 164
EGP+ G+ D++P E++ I L +P L R A+ C+ + P + + L
Sbjct: 273 EGPNNGYFDKLPYELIQLILNHLT-----LPDLCRLAQTCKLLSQHCCDPLQYIHLNLQ- 326
Query: 165 PLVGRPAKGGVKAEKKLLASLEWLMPN--------------RF-----SQLQRLTLI--H 203
P + ++ + ++WL + RF S+L RL L H
Sbjct: 327 PYWAKLDDTSLEFLQSRCTLVQWLNLSWTGNRGFISVAGFSRFLKVCGSELVRLELSCSH 386
Query: 204 WKSQ----LVGECCPRLTFLKLSGCHGVTADALVMLAKACCQLHSLDLQHSMVESTAVVS 259
+ ++ ++ E CP L L LS C + A +AK C L L L + VE TA++S
Sbjct: 387 FLNETCLEVISEMCPNLQALNLSSCDKLPPQAFNHIAK-LCSLKRLVLYRTKVEQTALLS 445
Query: 260 FLEEAGSRMR-KLWLTYSSQTTAILGALLGSCCPQLQVLEV--STGINRNSIPLQLPVEA 316
L L + ++ +++G+ C +L+ L++ I N I
Sbjct: 446 ILNFCSELQHLSLGSCVMIEDYDVIASMIGAKCKKLRTLDLWRCKNITENGI------AE 499
Query: 317 LQKGCPQLQVLRLLNLMWLPKPPGRGVAPGPGFPSLEELCLASSTCNFVSNEVLGRLLHG 376
L GCP L+ L L L G P+L++L L ++ V + + L
Sbjct: 500 LASGCPLLEELDLGWCPTLQSSTGCFTRLAHQLPNLQKLFLTAN--RSVCDTDIDELACN 557
Query: 377 SPNLRLLDLRGCARITPAGLQDL--PCRELEQLHLGLYGTSDRLTLAKEGSPF 427
L+ LD+ G ++PA L+ L C++L L + D + + + F
Sbjct: 558 CTRLQQLDILGTRMVSPASLRKLLESCKDLSLLDVSFCSQIDNRAVLELNASF 610
Score = 30.0 bits (66), Expect = 5.5
Identities = 33/107 (30%), Positives = 42/107 (39%), Gaps = 7/107 (6%)
Query: 401 CRELEQLHLGLYGTSDRLTLAKEGSPFLTQKWCHTLRELDLSGQGFSEKDLEQALAAFLS 460
C L+ +HL L +L + S Q C ++ L+LS G + FL
Sbjct: 315 CDPLQYIHLNLQPYWAKLD---DTSLEFLQSRCTLVQWLNLSWTGNRGFISVAGFSRFLK 371
Query: 461 TPGGSHPALCSLNLRGTRVTPSTVSSVISS-CPGLLYLNLESCRCLP 506
G L L L + T VIS CP L LNL SC LP
Sbjct: 372 VCGSE---LVRLELSCSHFLNETCLEVISEMCPNLQALNLSSCDKLP 415
>gi|22748931 F-box and leucine-rich repeat protein 14 [Homo sapiens]
Length = 418
Score = 63.5 bits (153), Expect = 4e-10
Identities = 102/400 (25%), Positives = 163/400 (40%), Gaps = 68/400 (17%)
Query: 118 EILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWHTVTLSSPLVGRPAKGGVKA 177
E+L IFG L D GRAA+VC W++AA ++W GV+A
Sbjct: 11 ELLAMIFGYLDVRDK-----GRAAQVCTAWRDAAYHKSVWR---------------GVEA 50
Query: 178 EKKLLASLEWLMPNRFSQ-LQRLTLIHWKSQL--VGECCPRLTFLKLSGCHGVTADALVM 234
+ L + L P+ ++ ++R+ ++ + L V + + L LSGC+ +T + L
Sbjct: 51 KLHLRRANPSLFPSLQARGIRRVQILSLRRSLSYVIQGMANIESLNLSGCYNLTDNGLGH 110
Query: 235 LAKACCQLHSLDLQHSMVESTAVVSFLEEAGSRMRKLWLTYSSQTTAILGALLGSCCPQL 294
+F++E GS +R L L+ Q T + L
Sbjct: 111 ------------------------AFVQEIGS-LRALNLSLCKQITDSSLGRIAQYLKGL 145
Query: 295 QVLEVSTGINRNSIPLQLPVEALQK-GCPQLQVLRLLNLMWLPKPPGRGVAPGPGFPSLE 353
+VLE+ N + L L LQ+ L+ R L+ + + G + G LE
Sbjct: 146 EVLELGGCSNITNTGLLLIAWGLQRLKSLNLRSCRHLSDVGIGHLAGMTRSAAEGCLGLE 205
Query: 354 ELCLASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDLPCRELEQLHLGLYG 413
+L L C +++ L + G LRLL+L C I+ AGL LHL G
Sbjct: 206 QLTL--QDCQKLTDLSLKHISRGLTGLRLLNLSFCGGISDAGL----------LHLSHMG 253
Query: 414 TSDRLTLAKEGSPFLTQKWCHTLRELDLSG--QGFSEKDLEQALAAFLSTPGGSHPALCS 471
+ L L + T + L LSG F +K +Q+LA G L S
Sbjct: 254 SLRSLNLRSCDNISDTGIMHLAMGSLRLSGLDVSFCDKVGDQSLAYIAQGLDG----LKS 309
Query: 472 LNLRGTRVTPSTVSSVISSCPGLLYLNLESC-RCLPRGLK 510
L+L ++ ++ ++ GL LN+ C R +GL+
Sbjct: 310 LSLCSCHISDDGINRMVRQMHGLRTLNIGQCVRITDKGLE 349
>gi|27734755 F-box and leucine-rich repeat protein 20 [Homo sapiens]
Length = 436
Score = 60.1 bits (144), Expect = 5e-09
Identities = 98/429 (22%), Positives = 159/429 (37%), Gaps = 43/429 (10%)
Query: 114 RIPLEILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWHTVTL---SSPLVGRP 170
++P E+L++IF L L R A+V R W A + W + L + GR
Sbjct: 27 KLPKELLLRIFSFLDVVT-----LCRCAQVSRAWNVLALDGSNWQRIDLFDFQRDIEGRV 81
Query: 171 AKGGVKAEKKLLASLEWLMPNRFSQLQRLTLIHWKSQLVGECCPRLTFLKLSGCHGVTAD 230
+ K L L S L + + + C + L L+GC T
Sbjct: 82 VENISKRCGGFLRKL--------SLRGCLGVGDNALRTFAQNCRNIEVLNLNGCTKTTDA 133
Query: 231 ALVMLAKACCQLHSLDLQHSMVESTAVVSFLEEAGSRMRKLWLTYSSQTTAILGALLGSC 290
L+K C +L LDL + + L E + +L +++ Q T L
Sbjct: 134 TCTSLSKFCSKLRHLDLASCTSITNMSLKALSEGCPLLEQLNISWCDQVTKDGIQALVRG 193
Query: 291 CPQLQVLEVSTGINRNSIPLQLPVEALQ---KGCPQLQVLRLLNLMWLPKPPGRGVAPGP 347
C L+ L + QL EAL+ CP+L L L + + +
Sbjct: 194 CGGLKALFLKG-------CTQLEDEALKYIGAHCPELVTLNLQTCLQITDEGLITIC--R 244
Query: 348 GFPSLEELCLASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDLP--CRELE 405
G L+ LC +S C+ +++ +L L P LR+L++ C+++T G L C ELE
Sbjct: 245 GCHKLQSLC--ASGCSNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHELE 302
Query: 406 QLHLGLYGTSDRLTLAKEGSPFLTQKWCHTLRELDLSGQGFSEKDLEQALAAFLSTPGGS 465
++ L + + + C L+ L LS D L +
Sbjct: 303 KMDL------EECVQITDSTLIQLSIHCPRLQVLSLSHCELITDD----GIRHLGNGACA 352
Query: 466 HPALCSLNLRGTRVTPSTVSSVISSCPGLLYLNLESCRCLPR-GLKRAYRGLEEVQWCLE 524
H L + L + + SC L + L C+ + R G+KR L ++
Sbjct: 353 HDQLEVIELDNCPLITDASLEHLKSCHSLERIELYDCQQITRAGIKRLRTHLPNIKVHAY 412
Query: 525 QLLTSPSPS 533
+P PS
Sbjct: 413 FAPVTPPPS 421
>gi|16306582 F-box and leucine-rich repeat protein 2 [Homo sapiens]
Length = 423
Score = 58.9 bits (141), Expect = 1e-08
Identities = 97/411 (23%), Positives = 157/411 (38%), Gaps = 33/411 (8%)
Query: 114 RIPLEILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWHTVTLSSPLVGRPAKG 173
++P E+L++IF L + L R A++ + W A + W + L + + +
Sbjct: 14 KLPKELLLRIFSFL-----DIVTLCRCAQISKAWNILALDGSNWQRIDLFNFQIDVEGRV 68
Query: 174 GVKAEKKLLASLEWLMPNRFSQLQRLTLIHWKSQLVGECCPRLTFLKLSGCHGVTADALV 233
K+ L L + +L + + C + L L+GC +T
Sbjct: 69 VENISKRCGGFLRKLSLRGCIGVGDSSL-----KTFAQNCRNIEHLNLNGCTKITDSTCY 123
Query: 234 MLAKACCQLHSLDLQHSMVESTAVVSFLEEAGSRMRKLWLTYSSQTTAILGALLGSCCPQ 293
L++ C +L LDL + + + + + E + L L++ Q T L C
Sbjct: 124 SLSRFCSKLKHLDLTSCVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEALVRGCRG 183
Query: 294 LQVLEVSTGINRNSIPLQLPVEALQKGCPQLQVLRLLNLMWLPKPPGRGVAP-GPGFPSL 352
L+ L + G QL EAL+ L LNL + GV G L
Sbjct: 184 LKAL-LLRGCT------QLEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQICRGCHRL 236
Query: 353 EELCLASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDLP--CRELEQLHLG 410
+ LCL S C+ +++ L L P L++L+ C+ +T AG L C ELE++ L
Sbjct: 237 QALCL--SGCSNLTDASLTALGLNCPRLQILEAARCSHLTDAGFTLLARNCHELEKMDL- 293
Query: 411 LYGTSDRLTLAKEGSPFLTQKWCHTLRELDLSGQGFSEKDLEQALAAFLSTPGGSHPALC 470
+ L + + C L+ L LS D LS H L
Sbjct: 294 -----EECILITDSTLIQLSIHCPKLQALSLSHCELITDD----GILHLSNSTCGHERLR 344
Query: 471 SLNLRGTRVTPSTVSSVISSCPGLLYLNLESCRCLPR-GLKRAYRGLEEVQ 520
L L + + +C GL L L C+ + R G+KR L V+
Sbjct: 345 VLELDNCLLITDVALEHLENCRGLERLELYDCQQVTRAGIKRMRAQLPHVK 395
>gi|161333854 F-box and leucine-rich repeat protein 13 isoform 2
[Homo sapiens]
Length = 690
Score = 49.7 bits (117), Expect = 7e-06
Identities = 71/317 (22%), Positives = 113/317 (35%), Gaps = 71/317 (22%)
Query: 188 LMPNRFSQLQRLTLIHWKSQL--------VGECCPRLTFLKLSGCHGVTADALVMLAKAC 239
L+P F LQ L+L + + +G C +L +L LSGC ++ +A +C
Sbjct: 290 LLPRHFHNLQNLSLAYCRRFTDKGLQYLNLGNGCHKLIYLDLSGCTQISVQGFRYIANSC 349
Query: 240 CQLHSLDLQHSMVESTAVVSFLEEAGSRMRKLWLTYSSQTTAILGALLGSC--------- 290
+ L + + V L E SR+ L T + + L +C
Sbjct: 350 TGIMHLTINDMPTLTDNCVKALVEKCSRITSLVFTGAPHISDCTFRALSACKLRKIRFEG 409
Query: 291 ---------------CPQLQVLEVST--GINRNSIPLQLPVEALQKGCPQLQVLRLLNLM 333
P L + ++ GI +S+ P++ QL VL L N +
Sbjct: 410 NKRVTDASFKFIDKNYPNLSHIYMADCKGITDSSLRSLSPLK-------QLTVLNLANCV 462
Query: 334 WLPKPPGRGVAPGPGFPSLEELCLASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCARITP 393
+ + GP + EL L S C +S+ + +L PNL L LR C +T
Sbjct: 463 RIGDMGLKQFLDGPASMRIRELNL--SNCVRLSDASVMKLSERCPNLNYLSLRNCEHLTA 520
Query: 394 AGLQ-----------DLPCRELEQLHLGLYG----------------TSDRLTLAKEGSP 426
G+ DL ++ L + T D + +
Sbjct: 521 QGIGYIVNIFSLVSIDLSGTDISNEGLNVLSRHKKLKELSVSECYRITDDGIQITDSAME 580
Query: 427 FLTQKWCHTLRELDLSG 443
L+ K CH L LD+SG
Sbjct: 581 MLSAK-CHYLHILDISG 596
>gi|161333852 F-box and leucine-rich repeat protein 13 isoform 1
[Homo sapiens]
Length = 735
Score = 49.3 bits (116), Expect = 9e-06
Identities = 57/243 (23%), Positives = 92/243 (37%), Gaps = 43/243 (17%)
Query: 188 LMPNRFSQLQRLTLIHWKSQL--------VGECCPRLTFLKLSGCHGVTADALVMLAKAC 239
L+P F LQ L+L + + +G C +L +L LSGC ++ +A +C
Sbjct: 290 LLPRHFHNLQNLSLAYCRRFTDKGLQYLNLGNGCHKLIYLDLSGCTQISVQGFRYIANSC 349
Query: 240 CQLHSLDLQHSMVESTAVVSFLEEAGSRMRKLWLTYSSQTTAILGALLGSC--------- 290
+ L + + V L E SR+ L T + + L +C
Sbjct: 350 TGIMHLTINDMPTLTDNCVKALVEKCSRITSLVFTGAPHISDCTFRALSACKLRKIRFEG 409
Query: 291 ---------------CPQLQVLEVST--GINRNSIPLQLPVEALQKGCPQLQVLRLLNLM 333
P L + ++ GI +S+ P++ QL VL L N +
Sbjct: 410 NKRVTDASFKFIDKNYPNLSHIYMADCKGITDSSLRSLSPLK-------QLTVLNLANCV 462
Query: 334 WLPKPPGRGVAPGPGFPSLEELCLASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCARITP 393
+ + GP + EL L S C +S+ + +L PNL L LR C +T
Sbjct: 463 RIGDMGLKQFLDGPASMRIRELNL--SNCVRLSDASVMKLSERCPNLNYLSLRNCEHLTA 520
Query: 394 AGL 396
G+
Sbjct: 521 QGI 523
Score = 38.9 bits (89), Expect = 0.012
Identities = 28/102 (27%), Positives = 50/102 (49%), Gaps = 5/102 (4%)
Query: 174 GVKAEKKLLASLEWLMPNRFSQLQRLTLIHWKSQLVGECCPRLTFLKLSGCHGVTADALV 233
G++A K LE L + SQL + + + + C LT L ++GC +T A+
Sbjct: 571 GIQAFCKSSLILEHLDVSYCSQLSDMII-----KALAIYCINLTSLSIAGCPKITDSAME 625
Query: 234 MLAKACCQLHSLDLQHSMVESTAVVSFLEEAGSRMRKLWLTY 275
ML+ C LH LD+ ++ + ++ L+ ++R L + Y
Sbjct: 626 MLSAKCHYLHILDISGCVLLTDQILEDLQIGCKQLRILKMQY 667
Score = 30.8 bits (68), Expect = 3.2
Identities = 48/213 (22%), Positives = 82/213 (38%), Gaps = 25/213 (11%)
Query: 209 VGECCPRLTFLKLSGCHGVTADALVMLAKACCQLHSLDLQHSMVESTAVVSFLEEAGSRM 268
+ E CP L +L L C +TA + + L S+DL + + + + SR
Sbjct: 500 LSERCPNLNYLSLRNCEHLTAQGIGYIVNIF-SLVSIDLSGTDISNEGL-----NVLSRH 553
Query: 269 RKLWLTYSSQTTAILGALLGSCCPQLQVLEVSTGINRNSIPLQLPVEALQKGCPQLQVLR 328
+KL S+ I + + C +LE ++ S + ++AL C L L
Sbjct: 554 KKLKELSVSECYRITDDGIQAFCKSSLILE-HLDVSYCSQLSDMIIKALAIYCINLTSLS 612
Query: 329 LLNLMWLPKPPGRGVAPGPGFPSLEELC-----LASSTCNFVSNEVLGRLLHGSPNLRLL 383
+ PK L C L S C +++++L L G LR+L
Sbjct: 613 IAGC---PK------ITDSAMEMLSAKCHYLHILDISGCVLLTDQILEDLQIGCKQLRIL 663
Query: 384 DLRGCARITPAGLQDLPCRELEQLHLGLYGTSD 416
++ C I+ Q + + +Q Y T+D
Sbjct: 664 KMQYCTNISKKAAQRMSSKVQQQ----EYNTND 692
>gi|16306595 S-phase kinase-associated protein 2 isoform 1 [Homo
sapiens]
Length = 424
Score = 46.6 bits (109), Expect = 6e-05
Identities = 49/185 (26%), Positives = 73/185 (39%), Gaps = 42/185 (22%)
Query: 99 PTPTPEEGPDAGWGDRIPLEILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWH 158
P E P W D +P E+L+ IF L +P L + + VC+RW AS +LW
Sbjct: 85 PKLNRENFPGVSW-DSLPDELLLGIFSCLC-----LPELLKVSGVCKRWYRLASDESLWQ 138
Query: 159 TVTLSS-----PLVGRPAKGGVKAEKKLLASLEWLMPNRF-------------------- 193
T+ L+ + GR GV A + + ++ + F
Sbjct: 139 TLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTL 198
Query: 194 -------SQLQRLTL--IHWKSQLVGECC--PRLTFLKLSGCHGVTADALVMLAKACCQL 242
S+LQ L+L + +V L L LSGC G + AL L +C +L
Sbjct: 199 HGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSSCSRL 258
Query: 243 HSLDL 247
L+L
Sbjct: 259 DELNL 263
>gi|14249170 S-phase kinase-associated protein 2 isoform 2 [Homo
sapiens]
Length = 410
Score = 46.6 bits (109), Expect = 6e-05
Identities = 49/185 (26%), Positives = 73/185 (39%), Gaps = 42/185 (22%)
Query: 99 PTPTPEEGPDAGWGDRIPLEILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWH 158
P E P W D +P E+L+ IF L +P L + + VC+RW AS +LW
Sbjct: 85 PKLNRENFPGVSW-DSLPDELLLGIFSCLC-----LPELLKVSGVCKRWYRLASDESLWQ 138
Query: 159 TVTLSS-----PLVGRPAKGGVKAEKKLLASLEWLMPNRF-------------------- 193
T+ L+ + GR GV A + + ++ + F
Sbjct: 139 TLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTL 198
Query: 194 -------SQLQRLTL--IHWKSQLVGECC--PRLTFLKLSGCHGVTADALVMLAKACCQL 242
S+LQ L+L + +V L L LSGC G + AL L +C +L
Sbjct: 199 HGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSSCSRL 258
Query: 243 HSLDL 247
L+L
Sbjct: 259 DELNL 263
>gi|24025682 F-box and leucine-rich repeat protein 16 [Homo sapiens]
Length = 479
Score = 46.6 bits (109), Expect = 6e-05
Identities = 98/399 (24%), Positives = 141/399 (35%), Gaps = 83/399 (20%)
Query: 63 ASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAPTPTPEEGPDAGWGDRIPLE---- 118
A++ P QPP P+ A S AA A P TP GP + P E
Sbjct: 41 ATKNRPCQPPPPPTLPPPSLAAPLSRAALAGGPC-----TPAGGPASALAPGHPAERPPL 95
Query: 119 -----ILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALW-------HTVTLSSPL 166
IL +F A + + A+VC+ W+ QP W H L + L
Sbjct: 96 ATDEKILNGLFWYFSACEKCV-----LAQVCKAWRRVLYQPKFWAGLTPVLHAKELYNVL 150
Query: 167 VGRP------------------------------------AKGGVKA---EKKLL--ASL 185
G +K GVKA ++ + A L
Sbjct: 151 PGGEKEFVNLQGFAARGFEGFCLVGVSDLDICEFIDNYALSKKGVKAMSLKRSTITDAGL 210
Query: 186 EWLMPNRFSQLQRLTLI----HWKSQLVGECCPRLTFLKLSGCHGVTADALVMLAKACCQ 241
E +M + + RL L ++ L R+T L +S C V DA+ +++
Sbjct: 211 E-VMLEQMQGVVRLELSGCNDFTEAGLWSSLSARITSLSVSDCINVADDAIAAISQLLPN 269
Query: 242 LHSLDLQHSMVESTAVVSFLEEAGSRMRKLWLTYSSQTTAILGALLGSCCPQLQVLEVST 301
L L LQ V TA+ F G L L + T + P L L +S
Sbjct: 270 LAELSLQAYHVTDTALAYFTARQGHSTHTLRLLSCWEITNHGVVNVVHSLPNLTALSLSG 329
Query: 302 GINRNSIPLQLPVEALQKGCPQLQVLRLLNLMWLPKPPGRGVA-PGPGFPSLEELCLASS 360
++L E L+K LR L+L W P+ + LEEL L
Sbjct: 330 CSKVTDDGVELVAENLRK-------LRSLDLSWCPRITDMALEYVACDLHRLEELVL--D 380
Query: 361 TCNFVSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDL 399
C +++ L L S +LR L LR C ++ GL+ L
Sbjct: 381 RCVRITDTGLSYLSTMS-SLRSLYLRWCCQVQDFGLKHL 418
Score = 37.0 bits (84), Expect = 0.045
Identities = 36/133 (27%), Positives = 57/133 (42%), Gaps = 17/133 (12%)
Query: 214 PRLTFLKLSGCHGVTADALVMLAKACCQLHSLD-----------LQHSMVESTAVVSFLE 262
P LT L LSGC VT D + ++A+ +L SLD L++ + + +
Sbjct: 320 PNLTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMALEYVACDLHRLEELVL 379
Query: 263 EAGSRMRKLWLTYSSQTTAILGALLGSCCPQLQVLEVSTGINRNSIPLQLPVEALQKGCP 322
+ R+ L+Y S +++ L CC Q+Q + + S+ L P GCP
Sbjct: 380 DRCVRITDTGLSYLSTMSSLRSLYLRWCC-QVQDFGLKHLLALGSLRLLSPA-----GCP 433
Query: 323 QLQVLRLLNLMWL 335
L L L+ L
Sbjct: 434 LLTTTGLSGLVQL 446
Score = 35.0 bits (79), Expect = 0.17
Identities = 47/169 (27%), Positives = 69/169 (40%), Gaps = 25/169 (14%)
Query: 350 PSLEELCLASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDLPC--RELEQL 407
P+L L L S C+ V+++ + + LR LDL C RIT L+ + C LE+L
Sbjct: 320 PNLTALSL--SGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMALEYVACDLHRLEEL 377
Query: 408 HLGL------YGTSDRLTLAKEGSPFLTQKWCHTLRELDLSGQGFSEKDLEQALAAFLST 461
L G S T++ S +L +WC + Q F K L + L +
Sbjct: 378 VLDRCVRITDTGLSYLSTMSSLRSLYL--RWCCQV-------QDFGLKHLLALGSLRLLS 428
Query: 462 PGGSHPALCSLNLRGTRVTPSTVSSVISSCPG-----LLYLNLESCRCL 505
P G P L + L G +++CPG Y + RCL
Sbjct: 429 PAGC-PLLTTTGLSGLVQLQELEELELTNCPGATPELFKYFSQHLPRCL 476
>gi|22547146 F-box and leucine-rich repeat protein 8 [Homo sapiens]
Length = 374
Score = 45.4 bits (106), Expect = 1e-04
Identities = 67/245 (27%), Positives = 95/245 (38%), Gaps = 48/245 (19%)
Query: 112 GDRIPLEILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWHTVTLSSP------ 165
G+ +P E+L IF L D AARVCR W AA+ A+WH +S
Sbjct: 5 GEGLPEEVLALIFRHLSLRDR-----AAAARVCRAWAAAATCSAVWHDTKISCECELEGM 59
Query: 166 ----------------LVGRPAKGGVKAEKKLLASLEWLMPNRFSQLQRLTL-------- 201
L P++ K ++ L ++ R L+ L L
Sbjct: 60 LPPYLSACLDHIHNLRLEFEPSR---KPSRRAAIELLMVLAGRAPGLRGLRLECRGEKPL 116
Query: 202 ------IHWKSQLVGECCPRLTFLKLSGCHGVTADALVM-LAKACCQLHSLDLQHS-MVE 253
+ V +L L L DALV+ A++C +LHSL L +S +V
Sbjct: 117 FDAGRDVLEAVHAVCGAASQLRHLDLRRLSFTLDDALVLQAARSCPELHSLFLDNSTLVG 176
Query: 254 STAVVSFLE--EAGSRMRKLWLTYSSQTTAILGALLGSCCPQLQVLEVSTGINRNSIPLQ 311
S S LE EA R+R L L +S + AIL AL +L + ++
Sbjct: 177 SVGPGSVLELLEACPRLRALGLHLASLSHAILEALAAPDRAPFALLALRCACPEDARASP 236
Query: 312 LPVEA 316
LP EA
Sbjct: 237 LPNEA 241
>gi|117938759 GNAS complex locus XLas [Homo sapiens]
Length = 1037
Score = 44.7 bits (104), Expect = 2e-04
Identities = 48/173 (27%), Positives = 64/173 (36%), Gaps = 25/173 (14%)
Query: 16 APRPRSAEDWWWDRLAPRGSGYHLLQSDSMLLVLSEPGPARPRAQRRASRRTPRQPPRGP 75
+P P A + +D+ A RG LLQ + P P A P PP P
Sbjct: 155 SPPPEEAMPFEFDQPAQRGCSQLLLQVPDL-------APGGPGAAG-----VPGAPPEEP 202
Query: 76 SAAAKPKAGLRSEAAAAPAPAPAPTPTPEEGPDAGWGDRIPLEILVQIFGLLVAADGPMP 135
A KAG R +P P T P E G+GD P L ++ + DG
Sbjct: 203 QALRPAKAGSRG----GYSPPPEET-MPFELDGEGFGDDSPPPGLSRV---IAQVDGSSQ 254
Query: 136 FLGRAARVCRRWQEAASQPALWHTVTLSSPLVGRPAKGGVKAEKKLLASLEWL 188
F AA R AA+ P LW +G P++ V+ S W+
Sbjct: 255 FAAVAASSAVRLTPAANAPPLW-----VPGAIGSPSQEAVRPPSNFTGSSPWM 302
Score = 30.0 bits (66), Expect = 5.5
Identities = 25/65 (38%), Positives = 26/65 (40%), Gaps = 4/65 (6%)
Query: 50 SEPGPARPR-AQRRASRRTPRQPPRG--PSAAAKPKAGLRSEAAAAPAPAPA-PTPTPEE 105
S PA P A+ P P G P A A P AG EA AAPA A
Sbjct: 431 SGAAPAAPADPDSGAAPDAPADPDSGAAPDAPADPDAGAAPEAPAAPAAAETRAAHVAPA 490
Query: 106 GPDAG 110
PDAG
Sbjct: 491 APDAG 495
Score = 30.0 bits (66), Expect = 5.5
Identities = 26/78 (33%), Positives = 34/78 (43%), Gaps = 20/78 (25%)
Query: 54 PARPRA-QRRASRRTPRQP----PRGPSAAAKPKAGLRSEAAAAPA-----------PAP 97
PA P A + RA+ P P P P+A+A A +R A+AAPA P+P
Sbjct: 474 PAAPAAAETRAAHVAPAAPDAGAPTAPAASATRAAQVRRAASAAPASGARRKIHLRPPSP 533
Query: 98 ----APTPTPEEGPDAGW 111
A PTP + W
Sbjct: 534 EIQAADPPTPRPTRASAW 551
>gi|190194416 F-box and leucine-rich repeat protein 15 [Homo
sapiens]
Length = 300
Score = 44.3 bits (103), Expect = 3e-04
Identities = 37/122 (30%), Positives = 55/122 (45%), Gaps = 5/122 (4%)
Query: 209 VGECCPRLTFLKLSGCHGVTADALVMLAKACCQLHSLDLQH-SMVESTAVVSFLEEAGSR 267
+ E CPRL L L+ C V AL LA C L LDL ++ A+V + G+
Sbjct: 135 LAEGCPRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGAG 194
Query: 268 MRKLWLTYSSQTTAILGALLGSCCPQLQVLEVSTGINRNSIPLQLPVEALQKGCPQLQVL 327
+R L L ++ L CP+L L+++ + S V L + CP L+ L
Sbjct: 195 LRSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSD----GVRTLAEYCPVLRSL 250
Query: 328 RL 329
R+
Sbjct: 251 RV 252
Score = 42.7 bits (99), Expect = 8e-04
Identities = 45/135 (33%), Positives = 61/135 (45%), Gaps = 12/135 (8%)
Query: 316 ALQKGCPQLQVLRLLNLMWLPKPPGRGVAPGPGFPSLEELCLASSTCNFVSNEVLGRLL- 374
AL +GCP+LQ L L + W+ RG+A P+LEEL L + C + +E + L
Sbjct: 134 ALAEGCPRLQRLSLAHCDWVDGLALRGLA--DRCPALEELDL--TACRQLKDEAIVYLAQ 189
Query: 375 HGSPNLRLLDLRGCARITPAGLQDLPCRELEQLHLGLYGT----SDRLTLAKEGSPFLTQ 430
LR L L A + A +Q+L E HL L G SD + E P L
Sbjct: 190 RRGAGLRSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAEYCPVLRS 249
Query: 431 ---KWCHTLRELDLS 442
+ CH + E LS
Sbjct: 250 LRVRHCHHVAESSLS 264
Score = 39.7 bits (91), Expect = 0.007
Identities = 45/154 (29%), Positives = 70/154 (45%), Gaps = 16/154 (10%)
Query: 352 LEELCLASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDLP--CRELEQLHL 409
L+EL LA ++S+E L +L +P LR + L GC +++ L L C L++L L
Sbjct: 89 LQELALAPCH-EWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPRLQRLSL 147
Query: 410 GLYGTSDRLTLAKEGSPFLTQKWCHTLRELDLSGQGFSEKDLEQALAAFLSTPGGSHPAL 469
D L L C L ELDL+ + + L+ +L+ G+ L
Sbjct: 148 AHCDWVDGLALRGLADR------CPALEELDLT----ACRQLKDEAIVYLAQRRGA--GL 195
Query: 470 CSLNLR-GTRVTPSTVSSVISSCPGLLYLNLESC 502
SL+L V + V + +CP L +L+L C
Sbjct: 196 RSLSLAVNANVGDAAVQELARNCPELHHLDLTGC 229
Score = 33.5 bits (75), Expect = 0.50
Identities = 19/53 (35%), Positives = 29/53 (54%)
Query: 213 CPRLTFLKLSGCHGVTADALVMLAKACCQLHSLDLQHSMVESTAVVSFLEEAG 265
CP L L L+GC V +D + LA+ C L SL ++H + + +S L + G
Sbjct: 218 CPELHHLDLTGCLRVGSDGVRTLAEYCPVLRSLRVRHCHHVAESSLSRLRKRG 270
>gi|157168349 F-box and leucine-rich repeat protein 19 [Homo
sapiens]
Length = 694
Score = 43.1 bits (100), Expect = 6e-04
Identities = 90/354 (25%), Positives = 131/354 (37%), Gaps = 75/354 (21%)
Query: 48 VLSEP-GPARPRAQRRASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAPTPTPEEG 106
+LS P GPA P + R R PPR P E P A + P P
Sbjct: 381 LLSWPLGPAPPPRPPQLERHVVRPPPRSP------------EPDTLPLAAGSDHPLPR-- 426
Query: 107 PDAGWGDRIPLEILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWHTVTLS-SP 165
A W +++F L GP L RVCR W LW + LS
Sbjct: 427 --AAW---------LRVFQHL----GPRE-LCICMRVCRTWSRWCYDKRLWPRMDLSRRK 470
Query: 166 LVGRPAKGGVKAEKKLLASLEWLMPNRFSQLQRLTLIHWKSQLVGECCPRLTFLKLSGCH 225
+ P GV + L W ++ + L + +LV LSGC
Sbjct: 471 SLTPPMLSGVVRRQPRALDLSWTGVSKKQLMWLLNRLQGLQELV-----------LSGCS 519
Query: 226 GVTADALVMLAKACCQLHSLDLQHSMVESTAVVSFLEEA-GSRMRKLWL----TYSSQTT 280
++ AL +L LDL+ ++E+ S++R+L L T QT
Sbjct: 520 WLSVSALGSAPLPALRL--LDLR-----------WIEDVKDSQLRELLLPPPDTKPGQTE 566
Query: 281 AILGALLGSCCPQLQVLEVSTGINRNSIPLQLPVEALQKGCPQLQVLRLLNLMWLPKPPG 340
+ G L G +L LE++ + L + PQL L L + + P
Sbjct: 567 S-RGRLQGVAELRLAGLELT----------DASLRLLLRHAPQLSALDLSHCAHVGDPSV 615
Query: 341 RGVAPGPGFPSLEELC-LASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCARITP 393
+ P P E L L + C+ +++ L L P LR LDLR C +++P
Sbjct: 616 H-LLTAPTSPLRETLVHLNLAGCHRLTDHCL-PLFRRCPRLRRLDLRSCRQLSP 667
>gi|116268109 nucleotide-binding oligomerization domains 27 [Homo
sapiens]
Length = 1866
Score = 42.4 bits (98), Expect = 0.001
Identities = 82/300 (27%), Positives = 116/300 (38%), Gaps = 59/300 (19%)
Query: 217 TFLKLSGCHGVTADALVMLAKA---CCQLHSLDLQHSMVESTAVVSFLE--EAGSRMRKL 271
TF S C V+ + L LA C L LDL ++ + + + E +++L
Sbjct: 1498 TFRLTSSC--VSTEGLAHLASGLGHCHHLEELDLSNNQFDEEGTKALMRALEGKWMLKRL 1555
Query: 272 WLTYSSQTTAILGALLGSCCPQLQVLEVSTGINRNSIPLQLPVEALQKGCPQL-QVLRLL 330
L++ ++ L ALL Q+ L+ S +NRNSI GC L + LR
Sbjct: 1556 DLSHLLLNSSTL-ALLTHRLSQMTCLQ-SLRLNRNSIG--------DVGCCHLSEALRAA 1605
Query: 331 NLMWLPKPPGRGVAPGPGFPSLEELCLASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCAR 390
SLEEL L+ + + L +L G P LR +DL G +
Sbjct: 1606 T-------------------SLEELDLSHNQIGDAGVQHLATILPGLPELRKIDLSGNSI 1646
Query: 391 ITPAGLQ----DLPCRELEQLHLGLYGTSDRLTLAKEGSPFLTQKWCHTLRELDLSGQGF 446
+ G+Q + CR LE+L LG D L L Q+ LR L L F
Sbjct: 1647 SSAGGVQLAESLVLCRRLEELMLGCNALGDPTALG------LAQELPQHLRVLHLP---F 1697
Query: 447 SEKDLEQALAAFLSTPGGSHPALCSL---NLRGTRVTPSTVSSVISSCPGLLYLNLESCR 503
S AL+ + G H SL NL G V P L ++L SC+
Sbjct: 1698 SHLGPGGALSLAQALDGSPHLEEISLAENNLAG------GVLRFCMELPLLRQIDLVSCK 1751
>gi|54112382 F-box and leucine-rich repeat protein 10 isoform a [Homo
sapiens]
Length = 1336
Score = 40.8 bits (94), Expect = 0.003
Identities = 50/190 (26%), Positives = 72/190 (37%), Gaps = 31/190 (16%)
Query: 65 RRTPRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAPTPTPEEGP-DAGWGDRIPLEILVQI 123
R PR R P + + PK P P +P P+ P D G + E+ + +
Sbjct: 1017 RSPPRVISRPPPSVSPPKCIQMERHVIRPPPI---SPPPDSLPLDDGAAHVMHREVWMAV 1073
Query: 124 FGLLVAADGPMPFLGRAARVCRRWQEAASQPALWHTVTLS-----SPLVGRPAKGGVKAE 178
F L D L RVCR W LW + L+ +PL+ G+
Sbjct: 1074 FSYLSHQD-----LCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLM----LSGIIRR 1124
Query: 179 KKLLASLEWLMPNRFSQLQRLTLIHWKSQLVGECCPRLTFLKLSGCHGVTADALVMLAKA 238
+ + L W S+ Q LI+ P L L LSGC + AL + +
Sbjct: 1125 QPVSLDLSW---TNISKKQLSWLIN--------RLPGLRDLVLSGCSWIAVSAL--CSSS 1171
Query: 239 CCQLHSLDLQ 248
C L +LD+Q
Sbjct: 1172 CPLLRTLDVQ 1181
>gi|54112380 F-box and leucine-rich repeat protein 10 isoform b [Homo
sapiens]
Length = 1265
Score = 40.8 bits (94), Expect = 0.003
Identities = 50/190 (26%), Positives = 72/190 (37%), Gaps = 31/190 (16%)
Query: 65 RRTPRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAPTPTPEEGP-DAGWGDRIPLEILVQI 123
R PR R P + + PK P P +P P+ P D G + E+ + +
Sbjct: 948 RSPPRVISRPPPSVSPPKCIQMERHVIRPPPI---SPPPDSLPLDDGAAHVMHREVWMAV 1004
Query: 124 FGLLVAADGPMPFLGRAARVCRRWQEAASQPALWHTVTLS-----SPLVGRPAKGGVKAE 178
F L D L RVCR W LW + L+ +PL+ G+
Sbjct: 1005 FSYLSHQD-----LCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLM----LSGIIRR 1055
Query: 179 KKLLASLEWLMPNRFSQLQRLTLIHWKSQLVGECCPRLTFLKLSGCHGVTADALVMLAKA 238
+ + L W S+ Q LI+ P L L LSGC + AL + +
Sbjct: 1056 QPVSLDLSW---TNISKKQLSWLIN--------RLPGLRDLVLSGCSWIAVSAL--CSSS 1102
Query: 239 CCQLHSLDLQ 248
C L +LD+Q
Sbjct: 1103 CPLLRTLDVQ 1112
>gi|24308207 leucine rich repeat containing 47 [Homo sapiens]
Length = 583
Score = 40.8 bits (94), Expect = 0.003
Identities = 48/175 (27%), Positives = 67/175 (38%), Gaps = 29/175 (16%)
Query: 322 PQLQVLRLLNLMWLPKPPGRGVAPG--PGFPSLEELCLASSTCNFVSNEVLGRLLHGSPN 379
P L+VL L PPG+G+ P PG P L+ L L+ + E+ L +P
Sbjct: 99 PALRVLDLSGNALEALPPGQGLGPAEPPGLPQLQSLNLSGNRL----RELPADLARCAPR 154
Query: 380 LRLLDLRG-CARITPAGLQDLPCRELEQLHLGLYGTSDRLTLAKEGSPFLTQKWCH--TL 436
L+ L+L G C PA E G L A L+ H +L
Sbjct: 155 LQSLNLTGNCLDSFPA----------ELFRPGALPLLSELAAADNCLRELSPDIAHLASL 204
Query: 437 RELDLSGQGFSEKDLEQALAAFLSTPGGSHPALCSLNLRGTRVTPSTVSSVISSC 491
+ LDLS SE E A P L +N RG ++ + ++S C
Sbjct: 205 KTLDLSNNQLSEIPAELA----------DCPKLKEINFRGNKLRDKRLEKMVSGC 249
>gi|239750101 PREDICTED: hypothetical protein [Homo sapiens]
Length = 365
Score = 40.4 bits (93), Expect = 0.004
Identities = 27/60 (45%), Positives = 29/60 (48%), Gaps = 8/60 (13%)
Query: 51 EPGPARPRAQRR---ASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAPTPTPEEGP 107
EP PA PRA R A+RR P PP P A A+P G RS PA P PT P
Sbjct: 306 EPRPAEPRAPPRPPPAARRPP--PPPAPGAPARPLRGRRSH---GPAARPRAVPTTSLAP 360
>gi|18699730 solute carrier family 16, member 10 [Homo sapiens]
Length = 515
Score = 40.4 bits (93), Expect = 0.004
Identities = 24/70 (34%), Positives = 29/70 (41%), Gaps = 2/70 (2%)
Query: 45 MLLVLSEPGPAR--PRAQRRASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAPTPT 102
M+L EP AR AQ T PP GP + P+A + PA A
Sbjct: 1 MVLSQEEPDSARGTSEAQPLGPAPTGAAPPPGPGPSDSPEAAVEKVEVELAGPATAEPHE 60
Query: 103 PEEGPDAGWG 112
P E P+ GWG
Sbjct: 61 PPEPPEGGWG 70
>gi|30520327 F-box protein 27 [Homo sapiens]
Length = 283
Score = 40.4 bits (93), Expect = 0.004
Identities = 23/64 (35%), Positives = 31/64 (48%), Gaps = 7/64 (10%)
Query: 94 APAPAPTPTPEEGPDAGWGDRIPLEILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQ 153
A PAP P PEE D ++P E+L+ + + P LGR +VCR W+
Sbjct: 11 ARVPAPEPEPEEALDLS---QLPPELLLVVLSHVP----PRTLLGRCRQVCRGWRALVDG 63
Query: 154 PALW 157
ALW
Sbjct: 64 QALW 67
>gi|113416879 PREDICTED: hypothetical protein [Homo sapiens]
Length = 175
Score = 40.0 bits (92), Expect = 0.005
Identities = 22/59 (37%), Positives = 25/59 (42%)
Query: 52 PGPARPRAQRRASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAPTPTPEEGPDAG 110
PG A A R + R P PP P P AGL A + P+PAP P P G
Sbjct: 114 PGSAAAPAPGRDALRLPPPPPPPPERPRLPPAGLAGGPADSAPPSPAPAPRSRPAPRPG 172
>gi|4505101 microtubule-associated protein 7 [Homo sapiens]
Length = 749
Score = 40.0 bits (92), Expect = 0.005
Identities = 21/45 (46%), Positives = 26/45 (57%), Gaps = 1/45 (2%)
Query: 66 RTPRQPPRGPSAAAKPKAGLRSEA-AAAPAPAPAPTPTPEEGPDA 109
RTP +P GP+A A A + A A+APAPAP PTP P +
Sbjct: 415 RTPAEPEVGPAAPAMAPAPASAPAPASAPAPAPVPTPAMVSAPSS 459
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 39.7 bits (91), Expect = 0.007
Identities = 37/115 (32%), Positives = 40/115 (34%), Gaps = 23/115 (20%)
Query: 15 AAPRPRSAEDWWWDRLAPRGSGYHLLQSDSMLLVLSEPGPARPRAQRR------------ 62
AAP P A R P G G S L GPA P A+ R
Sbjct: 85 AAPEPPPA-----GRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAP 139
Query: 63 -----ASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAPTPTPEEGPDAGWG 112
A P P GP+ A P A L + A P P P P P P G AG G
Sbjct: 140 VPAAAAVAAGPEPAPAGPAKPAGP-AALAARAGPGPGPGPGPGPGPGPGKPAGPG 193
Score = 30.4 bits (67), Expect = 4.2
Identities = 36/124 (29%), Positives = 44/124 (35%), Gaps = 7/124 (5%)
Query: 48 VLSEPGPARPRAQRRASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAP---APAPTPTP- 103
+L P PA P + P P+A + P A + AAAP P APA P
Sbjct: 225 LLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPP 284
Query: 104 --EEGPDAGWGDRIPLEILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWHTVT 161
GP +P Q G AA P P G A V + A+ A V
Sbjct: 285 GHPAGPPTA-APAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVK 343
Query: 162 LSSP 165
SP
Sbjct: 344 AESP 347
>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
Length = 2157
Score = 39.7 bits (91), Expect = 0.007
Identities = 20/41 (48%), Positives = 22/41 (53%), Gaps = 1/41 (2%)
Query: 68 PRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAPTPTPEEGPD 108
P PP PS A P A + E A PAP PA PTPE P+
Sbjct: 508 PAAPPAAPSTPAPPPA-VPKELPAPPAPPPASAPTPETEPE 547
Score = 32.0 bits (71), Expect = 1.5
Identities = 19/63 (30%), Positives = 21/63 (33%), Gaps = 1/63 (1%)
Query: 50 SEPGPARPRAQRRASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAPTPTPEEGPDA 109
S G RP +P P P A + PAP P P P P GP
Sbjct: 363 SASGEERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKP-PLPPPHRGPAG 421
Query: 110 GWG 112
WG
Sbjct: 422 NWG 424
Score = 29.6 bits (65), Expect = 7.2
Identities = 27/85 (31%), Positives = 33/85 (38%), Gaps = 15/85 (17%)
Query: 49 LSEPGPAR----PRAQRRASRRTP---RQPPR-------GPSAAAKPKAGLRSEAAAAPA 94
L EPGP P + A +TP ++PP+ GP A KP G+ S P
Sbjct: 856 LEEPGPRPLPWPPGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPARGVGSGGQGPPP 915
Query: 95 PAPAPTPTPEEGPDAGWGDR-IPLE 118
P GP G R IP E
Sbjct: 916 PRRESRTETRWGPRPGSSRRGIPPE 940
>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
sapiens]
Length = 1636
Score = 39.7 bits (91), Expect = 0.007
Identities = 23/68 (33%), Positives = 28/68 (41%)
Query: 40 LQSDSMLLVLSEPGPARPRAQRRASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAP 99
L + S L PGP +P A P P GP AA G S + P+P P
Sbjct: 1027 LPAHSGALPFPSPGPPQPPHPPLAYGPAPSTRPMGPQAAPLTIRGPSSAGQSTPSPHLVP 1086
Query: 100 TPTPEEGP 107
+P P GP
Sbjct: 1087 SPAPSPGP 1094
>gi|30089926 F-box only protein 11 isoform 1 [Homo sapiens]
Length = 843
Score = 39.7 bits (91), Expect = 0.007
Identities = 31/120 (25%), Positives = 52/120 (43%), Gaps = 17/120 (14%)
Query: 47 LVLSEPGPARPRAQRRASRRT---------PRQPPRGPSAAAKPKAGLRSEAAAAPAPAP 97
+V E GP + + R+T + G S + G R++ A +
Sbjct: 1 MVAEESGPGAQNSPYQLRRKTLLPKRTACPTKNSMEGASTSTTENFGHRAKRARVSGKSQ 60
Query: 98 APTPTPEEGPDAGWGDRIPLEILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALW 157
+ P E +++P E++++IF L+ D L RAA VC+R+ E A+ P LW
Sbjct: 61 DLSAAPAE---QYLQEKLPDEVVLKIFSYLLEQD-----LCRAACVCKRFSELANDPILW 112
>gi|30089924 F-box only protein 11 isoform 2 [Homo sapiens]
Length = 686
Score = 39.7 bits (91), Expect = 0.007
Identities = 31/120 (25%), Positives = 52/120 (43%), Gaps = 17/120 (14%)
Query: 47 LVLSEPGPARPRAQRRASRRT---------PRQPPRGPSAAAKPKAGLRSEAAAAPAPAP 97
+V E GP + + R+T + G S + G R++ A +
Sbjct: 1 MVAEESGPGAQNSPYQLRRKTLLPKRTACPTKNSMEGASTSTTENFGHRAKRARVSGKSQ 60
Query: 98 APTPTPEEGPDAGWGDRIPLEILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALW 157
+ P E +++P E++++IF L+ D L RAA VC+R+ E A+ P LW
Sbjct: 61 DLSAAPAE---QYLQEKLPDEVVLKIFSYLLEQD-----LCRAACVCKRFSELANDPILW 112
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.424
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,485,714
Number of Sequences: 37866
Number of extensions: 1402646
Number of successful extensions: 15204
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 187
Number of HSP's successfully gapped in prelim test: 536
Number of HSP's that attempted gapping in prelim test: 11578
Number of HSP's gapped (non-prelim): 3307
length of query: 533
length of database: 18,247,518
effective HSP length: 107
effective length of query: 426
effective length of database: 14,195,856
effective search space: 6047434656
effective search space used: 6047434656
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.