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Search of human proteins with 13540590
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13540590 family with sequence similarity 117, member A [Homo
sapiens]
(453 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13540590 family with sequence similarity 117, member A [Homo ... 942 0.0
gi|55742678 glucocorticoid induced transcript 1 [Homo sapiens] 258 6e-69
gi|27735131 amyotrophic lateral sclerosis 2 (juvenile) chromosom... 198 1e-50
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 54 3e-07
gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens] 48 2e-05
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens] 45 1e-04
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 45 2e-04
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 45 2e-04
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap... 45 2e-04
gi|85815829 SH3-domain binding protein 1 [Homo sapiens] 44 3e-04
gi|134244285 Notch homolog 3 [Homo sapiens] 43 5e-04
gi|163965366 nascent polypeptide-associated complex alpha subuni... 42 0.001
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 41 0.002
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 41 0.002
gi|38201621 eukaryotic translation initiation factor 4 gamma, 1 ... 40 0.004
gi|38201627 eukaryotic translation initiation factor 4 gamma, 1 ... 40 0.004
gi|38201625 eukaryotic translation initiation factor 4 gamma, 1 ... 40 0.004
gi|38201623 eukaryotic translation initiation factor 4 gamma, 1 ... 40 0.004
gi|38201619 eukaryotic translation initiation factor 4 gamma, 1 ... 40 0.004
gi|149158690 HLA-B associated transcript-2 [Homo sapiens] 40 0.004
gi|113421234 PREDICTED: similar to NG5 protein [Homo sapiens] 40 0.006
gi|113420954 PREDICTED: similar to NG5 protein [Homo sapiens] 40 0.006
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap... 40 0.006
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap... 40 0.006
gi|153945734 teashirt zinc finger homeobox 2 [Homo sapiens] 39 0.007
gi|50409738 SRp25 nuclear protein isoform 3 [Homo sapiens] 39 0.010
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 39 0.013
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 39 0.013
gi|150170670 piccolo isoform 2 [Homo sapiens] 39 0.013
gi|150378539 piccolo isoform 1 [Homo sapiens] 39 0.013
>gi|13540590 family with sequence similarity 117, member A [Homo
sapiens]
Length = 453
Score = 942 bits (2436), Expect = 0.0
Identities = 453/453 (100%), Positives = 453/453 (100%)
Query: 1 MAGAAAGGRGGGAWGPGRGGAGGLRRGCSPPAPAGSPRAGLQPLRATIPFQLQQPHQRRD 60
MAGAAAGGRGGGAWGPGRGGAGGLRRGCSPPAPAGSPRAGLQPLRATIPFQLQQPHQRRD
Sbjct: 1 MAGAAAGGRGGGAWGPGRGGAGGLRRGCSPPAPAGSPRAGLQPLRATIPFQLQQPHQRRD 60
Query: 61 GGGRAASVPCSVAPEKSVCRPQPLQVRRTFSLDTILSSYLLGQWPRDADGAFTCCTNDKA 120
GGGRAASVPCSVAPEKSVCRPQPLQVRRTFSLDTILSSYLLGQWPRDADGAFTCCTNDKA
Sbjct: 61 GGGRAASVPCSVAPEKSVCRPQPLQVRRTFSLDTILSSYLLGQWPRDADGAFTCCTNDKA 120
Query: 121 TQTPLSWQELEGERASSCAHKRSASWGSTDHRKEISKLKQQLQRTKLSRSGKEKERGSPL 180
TQTPLSWQELEGERASSCAHKRSASWGSTDHRKEISKLKQQLQRTKLSRSGKEKERGSPL
Sbjct: 121 TQTPLSWQELEGERASSCAHKRSASWGSTDHRKEISKLKQQLQRTKLSRSGKEKERGSPL 180
Query: 181 LGDHAVRGALRASPPSFPSGSPVLRLSPCLHRSLEGLNQELEEVFVKEQGEEELLRILDI 240
LGDHAVRGALRASPPSFPSGSPVLRLSPCLHRSLEGLNQELEEVFVKEQGEEELLRILDI
Sbjct: 181 LGDHAVRGALRASPPSFPSGSPVLRLSPCLHRSLEGLNQELEEVFVKEQGEEELLRILDI 240
Query: 241 PDGHRAPAPPQSGSCDHPLLLLEPGNLASSPSMSLASPQPCGLASHEEHRGAAEELASTP 300
PDGHRAPAPPQSGSCDHPLLLLEPGNLASSPSMSLASPQPCGLASHEEHRGAAEELASTP
Sbjct: 241 PDGHRAPAPPQSGSCDHPLLLLEPGNLASSPSMSLASPQPCGLASHEEHRGAAEELASTP 300
Query: 301 NDKASSPGHPAFLEDGSPSPVLAFAASPRPNHSYIFKREPPEGCEKVRVFEEATSPGPDL 360
NDKASSPGHPAFLEDGSPSPVLAFAASPRPNHSYIFKREPPEGCEKVRVFEEATSPGPDL
Sbjct: 301 NDKASSPGHPAFLEDGSPSPVLAFAASPRPNHSYIFKREPPEGCEKVRVFEEATSPGPDL 360
Query: 361 AFLTSCPDKNKVHFNPTGSAFCPVNLMKPLFPGMGFIFRNCPSNPGSPLPPASPRPPPRK 420
AFLTSCPDKNKVHFNPTGSAFCPVNLMKPLFPGMGFIFRNCPSNPGSPLPPASPRPPPRK
Sbjct: 361 AFLTSCPDKNKVHFNPTGSAFCPVNLMKPLFPGMGFIFRNCPSNPGSPLPPASPRPPPRK 420
Query: 421 DPEASKASPLPFEPWQRTPPSEEPVLFQSSLMV 453
DPEASKASPLPFEPWQRTPPSEEPVLFQSSLMV
Sbjct: 421 DPEASKASPLPFEPWQRTPPSEEPVLFQSSLMV 453
>gi|55742678 glucocorticoid induced transcript 1 [Homo sapiens]
Length = 547
Score = 258 bits (660), Expect = 6e-69
Identities = 189/473 (39%), Positives = 235/473 (49%), Gaps = 97/473 (20%)
Query: 5 AAGGRGGGAWGPGRGGAGGLRRGCSPPAPAGSPRAGLQPLRATIPFQLQQPHQRRD---- 60
AA G G GA GG GG+ GC+P A AG LQP+RAT+P+QL + Q
Sbjct: 35 AAAGSGNGA-----GGGGGV--GCAPAAGAGRL---LQPIRATVPYQLLRGSQHSPTRPP 84
Query: 61 --------------GGGR----------AASVPCSVAPEKS------------------- 77
G R AA+ P AP
Sbjct: 85 VAAAAASLGSLPGPGAARGPSPSSPTPPAAAAPAEQAPRAKGRPRRSPESHRRSSSPERR 144
Query: 78 -----VCRPQPLQ---------VRRTFSLDTILSSYLLGQWPRDADGAFTCCTNDKATQT 123
VCR + +RRT SLDTI YL GQWPRD + C DKATQT
Sbjct: 145 SPGSPVCRADKAKSQQVRTSSTIRRTSSLDTITGPYLTGQWPRDPHVHYPSCMKDKATQT 204
Query: 124 PLSWQELEGERASSCAHKRSASWGSTDHRKE-ISKLKQQLQRTKLS-RSGKEKERGSPLL 181
P W E E+ S H+RSASWGS D KE I+KL+QQLQR+K S R KEK+R SPL
Sbjct: 205 PSCWAEEGAEKRS---HQRSASWGSADQLKEQIAKLRQQLQRSKQSSRHSKEKDRQSPLH 261
Query: 182 GDHAVRGALRA----SPPSFPSGSPVLRLS----PCLHRSLEGLNQELEEVFVKEQ-GEE 232
G+H +A S P S V + S PC ++EG++ ELE+VF+KE G+E
Sbjct: 262 GNHITISHTQATGSRSVPMPLSNISVPKSSVSRVPC---NVEGISPELEKVFIKENNGKE 318
Query: 233 ELLRILDIPDGHRAPAPPQ-SGSCDHPLLLLEPGNLASSPSMSLASPQPCGLASHEEHRG 291
E+ + LDIPDG RAP P S + P S S S SP E G
Sbjct: 319 EVSKPLDIPDGRRAPLPAHYRSSSTRSIDTQTPSVQERSSSCSSHSPCVSPFCPPESQDG 378
Query: 292 AAEELASTPNDKASSPGHPAFLEDGSPSPVLAFAASPRPNHSYIFKREPPEGCEKVRVFE 351
+ D+ + GS SP+ +A+SP+PN+SY+FKREPPEGCE+V+VFE
Sbjct: 379 SPCSTEDLLYDRDK--------DSGSSSPLPKYASSPKPNNSYMFKREPPEGCERVKVFE 430
Query: 352 EATSPGPDLAFLTSCPDKNKVHFNPTGSAFCPVNLMKPLFPGMGFIFRNCPSN 404
E S P A L SCPDKNKV+F PTGSAFCPV L+ PL P + +N P++
Sbjct: 431 EMASRQPISAPLFSCPDKNKVNFIPTGSAFCPVKLLGPLLPASDLMLKNSPNS 483
>gi|27735131 amyotrophic lateral sclerosis 2 (juvenile) chromosome
region, candidate 13 [Homo sapiens]
Length = 345
Score = 198 bits (503), Expect = 1e-50
Identities = 131/290 (45%), Positives = 170/290 (58%), Gaps = 28/290 (9%)
Query: 118 DKATQTPLSWQELEGERASSCAHKRSASWGSTDHRKEISKLKQQLQRTK-LSRSGKEKER 176
DKATQT +W E E+ +HKRSASWGSTD KEI+KL+QQLQR+K SR ++KER
Sbjct: 3 DKATQTESAWAEEYSEKKKG-SHKRSASWGSTDQLKEIAKLRQQLQRSKHSSRHHRDKER 61
Query: 177 GSPLLGDHAVRGALRASPPSFPSGSPVLRLSPC----LHRSLEGLNQELEEVFVKEQGE- 231
SP G+HA +A P + PV+ ++ S+EGLNQE+E + +KE GE
Sbjct: 62 QSPFHGNHAAINQCQAPVPK-SALIPVIPITKSTGSRFRNSVEGLNQEIE-IIIKETGEK 119
Query: 232 EELLRILDIPDGHRAPAP-PQSGSCDHPLLLLEPG-------NLASSPSMSLASPQPCGL 283
EE L DIPDGHRAP P Q S + PG N + S S+S S
Sbjct: 120 EEQLIPQDIPDGHRAPPPLVQRSSSTRSIDTQTPGGADRGSNNSSRSQSVSPTSFLTISN 179
Query: 284 ASHEEHRGAAEELASTPNDKASSPGHPAFLEDGSPSPVLAFAASPRPNHSYIFKREPPEG 343
EE +A++L P DK E+G+ SP+ +A SP+PN+SY+FKREPPEG
Sbjct: 180 EGSEESPCSADDLLVDPRDK----------ENGNNSPLPKYATSPKPNNSYMFKREPPEG 229
Query: 344 CEKVRVFEEATSPGPDLAFLTSCPDKNKVHFNP-TGSAFCPVNLMKPLFP 392
CE+V+VFEE + CPDKNKV+F P +GSAFC V+++KPL P
Sbjct: 230 CERVKVFEECSPKQLHEIPAFYCPDKNKVNFIPKSGSAFCLVSILKPLLP 279
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 53.9 bits (128), Expect = 3e-07
Identities = 77/270 (28%), Positives = 103/270 (38%), Gaps = 41/270 (15%)
Query: 189 ALRASPPSFPSGSPVLRLSPCLHRSLEGLNQELEEVFVKEQGEEELLRILDIPDGHRAPA 248
A R SPP P P L LH L++ LEE + EE L
Sbjct: 464 ASRLSPP--PEELPASPLPEALH-----LSRPLEESPLSPPPEESPLS-----------P 505
Query: 249 PPQSGSCDHPLLLLEPGNLA----SSPSMSLASP-QPCGLASHEEHRGAAEELASTPNDK 303
PP+S P LE L+ S PS +L +P P AS L+ P +
Sbjct: 506 PPESS----PFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEEL 561
Query: 304 ASSPGHPAFLEDGSPSPVLAFAASPRPNHSYIFKREPPEGCEKVRVFEEAT-SPGPDLAF 362
+SP P SP P + SP P S + PPE FEE+ SP P+ +
Sbjct: 562 PTSP--PPEASRLSPPPEES-PMSPPPEESPM--SPPPEASRLFPPFEESPLSPPPEESP 616
Query: 363 LTSCPDKNKVHFNPTGSAFCPVNLMKPLFPG--------MGFIFRNCPSNPGSPLPPASP 414
L+ P+ +++ P S P P+ P + + R P SPL P
Sbjct: 617 LSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPE 676
Query: 415 RPPPRKDPEASKASPLPFEPWQRTPPSEEP 444
P PEAS+ SP P + PP + P
Sbjct: 677 ESPTSPPPEASRLSPPPEDSPTSPPPEDSP 706
Score = 51.2 bits (121), Expect = 2e-06
Identities = 78/296 (26%), Positives = 105/296 (35%), Gaps = 68/296 (22%)
Query: 198 PSGSPVLRLSP-------CLHRSLEGLNQELEEVFVKEQGEEELLRILDIPDGHRAPAPP 250
P G V + P C + L +LE EE + +L P+ PP
Sbjct: 396 PKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEE--MPLLPPPEESPLSPPP 453
Query: 251 QSGSCDHPLLLLEPGNLASSPSMSLASPQPCGLASHEEHRGAAEELASTPNDKA------ 304
+ P E L+ P ASP P L R E S P +++
Sbjct: 454 EESPTSPPP---EASRLSPPPEELPASPLPEAL---HLSRPLEESPLSPPPEESPLSPPP 507
Query: 305 -SSPGHP------AFLEDGSPSPVLAFAASPRPNHSYI---FKREP----PEGCEKVRVF 350
SSP P + E+ PSP L SP P S + F+ P PE
Sbjct: 508 ESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPE-------- 559
Query: 351 EEATSPGPDLAFLTSCPDKNKVHFNPTGSAFCPVNLMKPLFPGMGFIFRNCPSNPG---- 406
E TSP P+ + L+ P+++ + P S P LFP F P +P
Sbjct: 560 ELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPP----FEESPLSPPPEES 615
Query: 407 -----------SPLPPASPRPPPRKD------PEASKASPLPFEPWQRTPPSEEPV 445
SP P SP PP ++ PE S+ SPLP PP E P+
Sbjct: 616 PLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPL 671
Score = 43.5 bits (101), Expect = 4e-04
Identities = 86/328 (26%), Positives = 113/328 (34%), Gaps = 64/328 (19%)
Query: 154 EISKLKQQLQRTKLSRSGKEKERGSPLLGDHAVRGALRASPPSFPSGSPVLRLSPCLHRS 213
E L + L+ + LS +E P + + L SP S P SP SP L
Sbjct: 481 EALHLSRPLEESPLSPPPEESPLSPP--PESSPFSPLEESPLSPPEESPP---SPALETP 535
Query: 214 LEG------LNQELEEVFVKEQGEE-------ELLRILDIPDGHRAPAPPQSGSCDHP-- 258
L L+ EE + EE E R+ P+ PP+ P
Sbjct: 536 LSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPE 595
Query: 259 ----LLLLEPGNLASSPSMSLASPQPCGLASHEEHRGAAEELASTPNDKASSP------- 307
E L+ P S SP P A L+ P D SP
Sbjct: 596 ASRLFPPFEESPLSPPPEESPLSPPP-----------EASRLSPPPEDSPMSPPPEESPM 644
Query: 308 GHPAFLEDGSPSPVLAFAASPRPNHSYIFKREPPEGCEKVRVFEEATSPGPDLAFLTSCP 367
P + SP PV++ SP P S + PPE E TSP P+ + L+ P
Sbjct: 645 SPPPEVSRLSPLPVVS-RLSPPPEESPL--SPPPE--------ESPTSPPPEASRLSPPP 693
Query: 368 DKNKVHFNPTGSAFCPV---NLMK------PLFPGMGFIFRNCPSNPGSPLPPASPRPPP 418
+ + P S P +LM PL P + + CP + G L P P
Sbjct: 694 EDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLP-LPEEPQLCPRSEGPHLSPRPEEPHL 752
Query: 419 RKDPEASKASPLPFEPWQRTPPSEEPVL 446
PE SP EP +P EEP L
Sbjct: 753 SPRPEEPHLSPQAEEP-HLSPQPEEPCL 779
Score = 38.5 bits (88), Expect = 0.013
Identities = 49/213 (23%), Positives = 65/213 (30%), Gaps = 55/213 (25%)
Query: 249 PPQSGSCDHPLLLLEPGNLAS----------SPSMSLASPQPCGLASHEEHRGAAEELAS 298
PP G D P G L +P S PQ GL + A+ LA
Sbjct: 2301 PPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAP 2360
Query: 299 TPNDKASSPGHPAFLEDGS-PSPVLAFAASPRPNHSYIFKREPPEGCEKVRVFEEATSPG 357
+P P HP GS P +PRP + PPE C + P
Sbjct: 2361 SP------PSHPDIFRPGSYTDPYAQPPLTPRP------QPPPPESC---CALPPRSLPS 2405
Query: 358 PDLAFLTSCPDKNKVHFNP------TGSAFCPVNLMKPLFPGMGFIFRNCPSNPGSPLPP 411
+ + + P +P + AFCP SP+ P
Sbjct: 2406 DPFSRVPASPQSQSSSQSPLTPRPLSAEAFCP-----------------------SPVTP 2442
Query: 412 ASPRPPPRKDPEASKASPLPFEPWQRTPPSEEP 444
P P P + S PF P + P + P
Sbjct: 2443 RFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPP 2475
Score = 35.4 bits (80), Expect = 0.11
Identities = 64/283 (22%), Positives = 87/283 (30%), Gaps = 42/283 (14%)
Query: 194 PPSFPSGSPVLRLSPCLHRSLEGLNQELEEVFVKEQGEEELLRILDIPDGHRAPAPPQSG 253
PP PS SP+L L+ EE+ + GE L L PD P P
Sbjct: 885 PPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIIT 944
Query: 254 SCDHPLLLLEPGNLA--------SSPSMSLASPQPCGLASHEEHRGAAEELASTPNDKAS 305
+ P L G L S P LA+P S + P
Sbjct: 945 AAAPPALS-PLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPP 1003
Query: 306 SPGHPAFLEDGSPSPVLAFA----ASPRPNHSYIFKREPPEGCEKVRVFEEATSPGPDLA 361
SPG P G SP+L SP HS + + PP C + SP +
Sbjct: 1004 SPGSPV----GPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIG 1059
Query: 362 FLTSCPDKNKVHF-----------------------NPTGSAFCPVNLMKPLFPGMGFIF 398
+ D+ ++H +P G CP P +
Sbjct: 1060 KVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLG 1119
Query: 399 RNCPSNPGSPLPPASPRPPPRKDPEAS--KASPLPFEPWQRTP 439
+ G P + P P AS K SP+ +P + P
Sbjct: 1120 EDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLDPEELAP 1162
Score = 35.4 bits (80), Expect = 0.11
Identities = 56/206 (27%), Positives = 70/206 (33%), Gaps = 48/206 (23%)
Query: 250 PQSGSCDHPLLLLEPGNLASSPSMSLASPQPCG-----LASHEEHRGAAEELASTPN--- 301
P+ S D+ + PG S L SP P G L +E GA+ PN
Sbjct: 2247 PRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGF 2306
Query: 302 -DKASSPGHPAFLEDGSPSPVLAFAASPRPNHSYIFKREPPEGCEKVRVFEEATSPGPDL 360
D SS H LE +P F A P S + E SPG L
Sbjct: 2307 VDSPSSGTHLGGLELKTPD---VFKAPLTPRASQV----------------EPQSPGLGL 2347
Query: 361 AFLTSCPDKNKVHFNPTGSAFCPVNLMKPLFPGMGFIFRNCPSNPGSPLPPASPRPPPRK 420
P + P + P P IFR PP +PRP P
Sbjct: 2348 R-----PQEPP-----------PAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQP-P 2390
Query: 421 DPEASKASP---LPFEPWQRTPPSEE 443
PE+ A P LP +P+ R P S +
Sbjct: 2391 PPESCCALPPRSLPSDPFSRVPASPQ 2416
Score = 33.5 bits (75), Expect = 0.41
Identities = 70/264 (26%), Positives = 93/264 (35%), Gaps = 37/264 (14%)
Query: 208 PCLHRSLEG--LNQELEEVFVKEQGEEELLRILD-----IPDGHRAPAPPQSGSCDHPLL 260
P L EG L+ + EE+ + Q EE L + P + PQS + P L
Sbjct: 786 PHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQS---EEPCL 842
Query: 261 LLEPGNLASSPSMSLA--SPQPCGLASHEEHRGAAEELA--STPNDKASSP--GHPAFLE 314
P SP + SP+P A EEL P + + SP G PA E
Sbjct: 843 SPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSE 902
Query: 315 DGSP--SPV---LAFAASPRPNHSYIFKREPPEGCEKVRVFEEATSPGPDLAFLTSCPDK 369
G P SP+ L + S P+ S P + A P P
Sbjct: 903 PGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFG 962
Query: 370 NKVHFNPTGSAFCPVNLMKPLFPGMGFIFRNC-----------PSNPGSPLPPASPRPPP 418
K +P P+ L P+ P NC P +PGSP+ PASP
Sbjct: 963 AKGDSDPESPLAAPI-LETPISPPPE---ANCTDPEPVPPMILPPSPGSPVGPASPILME 1018
Query: 419 RKDPEASKASPLPFEPWQRTPPSE 442
P+ S P Q +PPS+
Sbjct: 1019 PLPPQCSPLLQHSLVP-QNSPPSQ 1041
>gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens]
Length = 2303
Score = 47.8 bits (112), Expect = 2e-05
Identities = 97/375 (25%), Positives = 132/375 (35%), Gaps = 67/375 (17%)
Query: 4 AAAGGRGGGAWGPGRGGAGGLRRGCSPPAPAGSPRAG-----LQPLR----ATIPFQLQQ 54
+A RGGGA G G AG RR PAP GS G L+ LR A +P +L++
Sbjct: 1299 SACPERGGGAGGAGLHFAGHRRRE-EGPAPTGSRPRGAADQELELLRECLGAAVPARLRK 1357
Query: 55 PHQRRDGGGRAASVPC-------SVAPEKSVCRPQPLQVRRTFSLDTILSSYLLGQWPRD 107
G RA VP + A E C FS LS L PRD
Sbjct: 1358 VASALVPGRRALPVPVYMLVPAPAPAQEDDSCTDSAEGTPVNFSSAASLSDETLQGPPRD 1417
Query: 108 ADGAFTCCTNDKATQTPLSWQELEGERASSCAHKRSASWGSTDHRKEISKLKQQLQRTKL 167
G + T P S ++ G R + RSA S K + L+ L R
Sbjct: 1418 QPGG--PAGRQRPTGRPTSARQAMGHRHKAGGAGRSAE-QSRGAGKNRAGLELPLGRPPS 1474
Query: 168 SRSGKEKERGSPLLGDHAVRGALRASPP----------SFPSGSPVLRLSPCLHRSLEGL 217
+ + K+ + GD A++ +P P +P R+
Sbjct: 1475 APADKDGSKPGRTRGDGALQSLCLTTPTEEAVYCFYGNDSDEEPPAAAPTPTHRRT---- 1530
Query: 218 NQELEEVFVKEQGEEELLRILDIPDGHR-APAPPQSGSCDHPLLLLEPGNLA-------- 268
+ F +E+ P G + APAP ++ P +P +A
Sbjct: 1531 -SAIPRAFTRER-----------PQGRKEAPAPSKAAPAAPPPARTQPSLIADETPPCYS 1578
Query: 269 -SSPSMSLASPQPC-GLASHEEHRGAAEELASTPNDKASSPGHPAFLEDGSPSPVLAFAA 326
SS + SL+ P+P A H R A PG P D SPSP A
Sbjct: 1579 LSSSASSLSEPEPSEPPAVHPRGREPA---------VTKDPG-PGGGRDSSPSPRAAEEL 1628
Query: 327 SPRPNHSYIFKREPP 341
R S + +R PP
Sbjct: 1629 LQRCISSALPRRRPP 1643
>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
Length = 727
Score = 45.4 bits (106), Expect = 1e-04
Identities = 71/242 (29%), Positives = 94/242 (38%), Gaps = 25/242 (10%)
Query: 205 RLSPCLHRSLEGLNQELEEVFVKEQGEEELLRILDIPDGHRAPAPPQSGSCDHPLLLLEP 264
R S RS L Q F+++ +EE LR P H AP + PLL
Sbjct: 266 RSSNLQSRSFRILAQMTGTEFMQDP-DEEALRRSSTPIEH---APVCTSQATTPLLPASA 321
Query: 265 GNLASSPSMSLASPQPCGLASHEEHRGAAEELASTPNDKASSPGHPAFLEDGSPSPVLAF 324
A++ S S ASP LA+ H A + P ASSP + S SP +A
Sbjct: 322 QPPAAA-SPSAASPP---LATAAAHTAIASASTTAP---ASSPADSPRPQASSYSPAVAA 374
Query: 325 AASPRPNHSYIFKREPPEGCEKVRVFEEAT------SPGPDLAFLTSCPDKNKVHFNPTG 378
+++P + SY P K RV A+ P P + S P N ++PT
Sbjct: 375 SSAPATHTSY--SEGPAAPAPKPRVVTTASIRPSVYQPVPASTYSPS-PGAN---YSPTP 428
Query: 379 SAFCPVNLMKPLFPGMGFIFRNCPSNPGSPLPPASPRPPPRKDPEASKA-SPLPFEPWQR 437
P P P + P+ SP P +P P P +P S A S P EP R
Sbjct: 429 YTPSPAPAYTPS-PAPAYTPSPVPTYTPSPAPAYTPSPAPNYNPAPSVAYSGGPAEPASR 487
Query: 438 TP 439
P
Sbjct: 488 PP 489
>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 44.7 bits (104), Expect = 2e-04
Identities = 60/223 (26%), Positives = 82/223 (36%), Gaps = 41/223 (18%)
Query: 237 ILDIPDGHRAPAPPQSGSCDHPLLLLEPGNLASSPSMSLASPQPCGLASHEEHRGAAEEL 296
I + P G P+PP + PLLL P P S+A P P L
Sbjct: 154 ISEPPGGSPLPSPPSTAPPPPPLLLEPP------PPPSMAPPPPPVLE------------ 195
Query: 297 ASTPNDKASSPGHPAFLEDGSPSPVLAFAASPRP------------NHSYIFKREPPEGC 344
A +P SSP P + P+P LAF A P P H+ + PP G
Sbjct: 196 ALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGV 255
Query: 345 EKVRVFEEATSPGPDLAFLTSCPDKNKVHFNPTGSAFCPVNLMKPLFPGMGFIFRNCPSN 404
K + + G + P ++ P GSA P FP F+ P
Sbjct: 256 TKWK--SDVALNGRQAEATRASPPRSPA--EPKGSALGPNPEPHLTFPRS---FKVPPPT 308
Query: 405 P--GSPLPPASPRPPPRKDPEASKASP--LPFEPWQRTPPSEE 443
P S +P + PRK+ A+K +P LP P P+ +
Sbjct: 309 PVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQ 351
Score = 33.5 bits (75), Expect = 0.41
Identities = 46/174 (26%), Positives = 56/174 (32%), Gaps = 35/174 (20%)
Query: 303 KASSPGHPAFLEDGS----PSPVLAFAAS---PRPNHSYIFKREPPEGCEKVRVFEEATS 355
+AS P PA + + P P L F S P P E E R E AT
Sbjct: 273 RASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATK 332
Query: 356 PGPDLAFLTSCPDKNKVHFNPTGSAF--------CPVNLMK--PLFPGMGFIFRNCPSNP 405
P + P H P + CP L P P +G
Sbjct: 333 KAP-----SRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERA 387
Query: 406 GSP-----LPPASPRPPPRKDPEASKASPLPFEP--------WQRTPPSEEPVL 446
G+P LPP +P PP P A PLP + +TP S P L
Sbjct: 388 GTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPAL 441
>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 44.7 bits (104), Expect = 2e-04
Identities = 60/223 (26%), Positives = 82/223 (36%), Gaps = 41/223 (18%)
Query: 237 ILDIPDGHRAPAPPQSGSCDHPLLLLEPGNLASSPSMSLASPQPCGLASHEEHRGAAEEL 296
I + P G P+PP + PLLL P P S+A P P L
Sbjct: 154 ISEPPGGSPLPSPPSTAPPPPPLLLEPP------PPPSMAPPPPPVLE------------ 195
Query: 297 ASTPNDKASSPGHPAFLEDGSPSPVLAFAASPRP------------NHSYIFKREPPEGC 344
A +P SSP P + P+P LAF A P P H+ + PP G
Sbjct: 196 ALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGV 255
Query: 345 EKVRVFEEATSPGPDLAFLTSCPDKNKVHFNPTGSAFCPVNLMKPLFPGMGFIFRNCPSN 404
K + + G + P ++ P GSA P FP F+ P
Sbjct: 256 TKWK--SDVALNGRQAEATRASPPRSPA--EPKGSALGPNPEPHLTFPRS---FKVPPPT 308
Query: 405 P--GSPLPPASPRPPPRKDPEASKASP--LPFEPWQRTPPSEE 443
P S +P + PRK+ A+K +P LP P P+ +
Sbjct: 309 PVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQ 351
Score = 33.5 bits (75), Expect = 0.41
Identities = 46/174 (26%), Positives = 56/174 (32%), Gaps = 35/174 (20%)
Query: 303 KASSPGHPAFLEDGS----PSPVLAFAAS---PRPNHSYIFKREPPEGCEKVRVFEEATS 355
+AS P PA + + P P L F S P P E E R E AT
Sbjct: 273 RASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATK 332
Query: 356 PGPDLAFLTSCPDKNKVHFNPTGSAF--------CPVNLMK--PLFPGMGFIFRNCPSNP 405
P + P H P + CP L P P +G
Sbjct: 333 KAP-----SRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERA 387
Query: 406 GSP-----LPPASPRPPPRKDPEASKASPLPFEP--------WQRTPPSEEPVL 446
G+P LPP +P PP P A PLP + +TP S P L
Sbjct: 388 GTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPAL 441
>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo
sapiens]
Length = 1188
Score = 44.7 bits (104), Expect = 2e-04
Identities = 60/223 (26%), Positives = 82/223 (36%), Gaps = 41/223 (18%)
Query: 237 ILDIPDGHRAPAPPQSGSCDHPLLLLEPGNLASSPSMSLASPQPCGLASHEEHRGAAEEL 296
I + P G P+PP + PLLL P P S+A P P L
Sbjct: 154 ISEPPGGSPLPSPPSTAPPPPPLLLEPP------PPPSMAPPPPPVLE------------ 195
Query: 297 ASTPNDKASSPGHPAFLEDGSPSPVLAFAASPRP------------NHSYIFKREPPEGC 344
A +P SSP P + P+P LAF A P P H+ + PP G
Sbjct: 196 ALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGV 255
Query: 345 EKVRVFEEATSPGPDLAFLTSCPDKNKVHFNPTGSAFCPVNLMKPLFPGMGFIFRNCPSN 404
K + + G + P ++ P GSA P FP F+ P
Sbjct: 256 TKWK--SDVALNGRQAEATRASPPRSPA--EPKGSALGPNPEPHLTFPRS---FKVPPPT 308
Query: 405 P--GSPLPPASPRPPPRKDPEASKASP--LPFEPWQRTPPSEE 443
P S +P + PRK+ A+K +P LP P P+ +
Sbjct: 309 PVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQ 351
Score = 33.5 bits (75), Expect = 0.41
Identities = 46/174 (26%), Positives = 56/174 (32%), Gaps = 35/174 (20%)
Query: 303 KASSPGHPAFLEDGS----PSPVLAFAAS---PRPNHSYIFKREPPEGCEKVRVFEEATS 355
+AS P PA + + P P L F S P P E E R E AT
Sbjct: 273 RASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATK 332
Query: 356 PGPDLAFLTSCPDKNKVHFNPTGSAF--------CPVNLMK--PLFPGMGFIFRNCPSNP 405
P + P H P + CP L P P +G
Sbjct: 333 KAP-----SRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERA 387
Query: 406 GSP-----LPPASPRPPPRKDPEASKASPLPFEP--------WQRTPPSEEPVL 446
G+P LPP +P PP P A PLP + +TP S P L
Sbjct: 388 GTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPAL 441
>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
Length = 701
Score = 43.9 bits (102), Expect = 3e-04
Identities = 51/183 (27%), Positives = 69/183 (37%), Gaps = 31/183 (16%)
Query: 290 RGAAEELASTPNDKASSPGHPAFLEDGSPSPVLAFAASPRPNHSYIFKREPPEGCEKVRV 349
R A+EEL ST ++ PA +P+P LA AA+ S + R P + R
Sbjct: 493 RLASEELPSTAVPTPATTPAPAPAPAPAPAPALASAATKERTESEVPPR--PASPKVTRS 550
Query: 350 FEEATSPGPDLAFLTSCPDKNKVHFNP---TGSAFCPVNLMKPLFPGMGFIFRNCPSNPG 406
E +P D+A T P + P +GS P PL PG G +PG
Sbjct: 551 PPETAAPVEDMARRTKRPAPARPTMPPPQVSGSRSSPP--APPLPPGSG--------SPG 600
Query: 407 SP----------------LPPASPRPPPRKDPEASKASPLPFEPWQRTPPSEEPVLFQSS 450
+P +PP P PP+ S+ SP P P S PV +
Sbjct: 601 TPQALPRRLVGSSLRAPTVPPPLPPTPPQPARRQSRRSPASPSPASPGPASPSPVSLSNP 660
Query: 451 LMV 453
V
Sbjct: 661 AQV 663
>gi|134244285 Notch homolog 3 [Homo sapiens]
Length = 2321
Score = 43.1 bits (100), Expect = 5e-04
Identities = 72/249 (28%), Positives = 95/249 (38%), Gaps = 39/249 (15%)
Query: 227 KEQGEEELLRILDIPDGHRAPAPPQSGSCDHPL--LLLEPG----NLASSPSMSLASPQP 280
+E+ ++++R+LD P G R+P P H L LL PG L ++ S S S +P
Sbjct: 2013 QERLHQDIVRLLDQPSGPRSPPGP------HGLGPLLCPPGAFLPGLKAAQSGSKKSRRP 2066
Query: 281 CGLA--SHEEHRGAAEELA-STPNDKASSPGHPAFLED-GSPSPVLAFAASPRPNHSYIF 336
G A + RG ++L + P A S + ++ SP P ASP F
Sbjct: 2067 PGKAGLGPQGPRGRGKKLTLACPGPLADSSVTLSPVDSLDSPRPFGGPPASPGG-----F 2121
Query: 337 KREPPEGCEKVRVFEEATSPGPDLAFLTSCPDKNKV----HFNPTGSAFCPVNLMKPLFP 392
E P A GP A L P V NP L P P
Sbjct: 2122 PLEGPYAAATATAVSLAQLGGPGRAGLGRQPPGGCVLSLGLLNPVAVPLDWARLPPPAPP 2181
Query: 393 GMGFIFRNCPS----NPGSPLPPASPRPPP--------RKDPEASKASPLPFEPWQRTPP 440
G F+ P NPG+P+ P RPPP + P A S P + R P
Sbjct: 2182 GPSFLLPLAPGPQLLNPGTPVSP-QERPPPYLAVPGHGEEYPAAGAHSSPPKARFLRV-P 2239
Query: 441 SEEPVLFQS 449
SE P L S
Sbjct: 2240 SEHPYLTPS 2248
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 41.6 bits (96), Expect = 0.001
Identities = 57/213 (26%), Positives = 77/213 (36%), Gaps = 54/213 (25%)
Query: 241 PDGHRAPAPPQSGSCDHPLLLLEPGNLASSPSMSLASPQPCGLASHEEHRGAAEELASTP 300
P R P S D P+ GNL+S S AS P S + G+ + A+T
Sbjct: 803 PQTKRPPTKKGSAGPDTPI-----GNLSSPVSPVEASFLPENSLSFQ---GSKDSPATTH 854
Query: 301 NDKASSPGHPAFLEDGSPSPVLAFAASPR---------PNHSYIFKREPPEGCEKVRVFE 351
+ SP G+P+P SP+ P S + P EG
Sbjct: 855 SPTPPSP-------KGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPAT----- 902
Query: 352 EATSPGPDLAFLTSCPDKNKVHFNPTGSAFCPVNLMKPLFPGMGFIFRNCPSNPGSPLPP 411
A P L+ +S P K + P G P + PS G+P PP
Sbjct: 903 PAPKQAPALSMTSSSPKKARATPAPKG---IPAS----------------PSPKGAPTPP 943
Query: 412 ASPRPPPRKDPEASKASPLPFEPWQRTPPSEEP 444
A+ P P+ P A+P P W TPP+ P
Sbjct: 944 AATPPSPKGGP----ATPSP--KWAPTPPAATP 970
Score = 40.0 bits (92), Expect = 0.004
Identities = 64/262 (24%), Positives = 91/262 (34%), Gaps = 44/262 (16%)
Query: 193 SPPSFPSGSPVLRLSPCLHRSLEGLNQELEEVFVKEQGEEELLRILDIPDGHRAPAPPQS 252
SP P+ S V LSP +G+ KE ++ + +G PAP Q+
Sbjct: 860 SPKGAPTPSAVTPLSP------KGVTLP-----PKETPTPSVVNLPFPKEGPATPAPKQA 908
Query: 253 GSCDHPLLLLEPGNLASSPSMSLASPQPCGLASHEEHRGAAEELASTPNDKASSPGHPAF 312
P L + +SSP + A+P P G+ + +GA A+TP P P+
Sbjct: 909 -----PALSMT----SSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPS- 958
Query: 313 LEDGSPSPVLAFAASPRPNHSYIFKREPPEGCEKVRVFEEATSPGPDLAFLTSCPDKNKV 372
+P+P A SP+ + P+G AT P P T P
Sbjct: 959 -PKWAPTPPAATPPSPKGGPA----TPSPKGAPTPPA---ATPPSPKGGPATPSPKGA-- 1008
Query: 373 HFNPTGSAFCPVN-----LMKPLFPGMGFIFRNCPSNP-----GSPLPPASPRPPPRKDP 422
PT A P + P G P +P +PLP +P P P
Sbjct: 1009 ---PTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLP 1065
Query: 423 EASKASPLPFEPWQRTPPSEEP 444
P TPP+ P
Sbjct: 1066 SPKGGPATPSLKGAPTPPAATP 1087
Score = 36.2 bits (82), Expect = 0.063
Identities = 64/262 (24%), Positives = 81/262 (30%), Gaps = 38/262 (14%)
Query: 192 ASPPSFPSGSPVLRLSPCLHRSLEGLNQELEEVFVKEQGEEELLRILDIPDGHRAPAPPQ 251
A+PPS P GSP P +G +G + P A P
Sbjct: 1038 ATPPS-PKGSPAATPLP------KGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSP 1090
Query: 252 SGSCDHPLLLLEPGNLASSPSMSLASPQPCGLASHEEHRGAAEELASTPNDKASSPGHPA 311
G P P A++P P P G + H+GA A+TP P
Sbjct: 1091 KGGPATPSPKGAPMPPAATP------PSPKGGLATPPHKGAPTTPAATPPSPKGGLATPP 1144
Query: 312 FLEDGSPSPVLAFAASPRPNHSYIFKREPPEGCEKVRVFEEATSPGPDLAFLTSCPD--- 368
G+P+ A SP+ PP+G AT P P T P
Sbjct: 1145 --PKGAPTTPAATPPSPKGG----LATPPPKGAPTTPA---ATPPSPKGGLATPSPKGAP 1195
Query: 369 --KNKVHFNPTGSAFCPVNLMKPLFPGM-------GFIFRNCPSNPGSPLPPASPRPPPR 419
+P G P P P G PS G+P PA+ P P+
Sbjct: 1196 TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLA---TPSPKGAPTTPAATPPSPK 1252
Query: 420 KDPEASKASPLPFEPWQRTPPS 441
P P P TPPS
Sbjct: 1253 GGPATPPPKGAPTPP-AATPPS 1273
Score = 34.3 bits (77), Expect = 0.24
Identities = 53/188 (28%), Positives = 66/188 (35%), Gaps = 39/188 (20%)
Query: 264 PGNLASSPSMSLASPQPCGLASHEEHRGAAEELASTPNDKASSPGHPAFLEDGSPSPVLA 323
P SP LA+P P +GA A+TP P P G+P+P
Sbjct: 1221 PAATPPSPKGGLATPSP---------KGAPTTPAATPPSPKGGPATPP--PKGAPTPP-- 1267
Query: 324 FAASPRPNHSYIFKREPPEGCEKVRVFEEATSPGPDLAFLTSCPDKNKVHFNPTGSAFCP 383
AA+P P+ P +G V T P P TS P PT A P
Sbjct: 1268 -AATP-PSLKGGLATPPHKGAPNPAV---VTPPSPKGGPATSPPKGA-----PTPPAATP 1317
Query: 384 VNLMKPLFPGMGFIFRNCPSNPGSPLPPASPRPPPRKDP------EASKASP-LPFEPWQ 436
+ PG P G+P PPA P P+ P +SK P P
Sbjct: 1318 PSPKGS--PGT-------PPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEG 1368
Query: 437 RTPPSEEP 444
TPP+ P
Sbjct: 1369 PTPPAATP 1376
Score = 32.3 bits (72), Expect = 0.91
Identities = 52/201 (25%), Positives = 63/201 (31%), Gaps = 36/201 (17%)
Query: 241 PDGHRAPAPPQSGSCDHPLLLLEPGNLASSPSMSLASPQPCGLASHEEHRGAAEELASTP 300
P PA P P P SP A+P P +GA A TP
Sbjct: 971 PSPKGGPATPSPKGAPTP-----PAATPPSPKGGPATPSP---------KGAPTPPAVTP 1016
Query: 301 NDKASSPGHPAFLEDGSPSPVLAFAASPRPNHSYIFKREPPEGCEKVRVFEEATSPGPDL 360
SP F + S P A P P S P+G T+P L
Sbjct: 1017 PSPKGSPAATPFPKGASTPPA---ATPPSPKGSPA-ATPLPKGAP--------TTPAATL 1064
Query: 361 AFLTSCPDKNKVHFNPTGSAFCPVNLMKPLFPGMGFIFRNCPSNPGSPLPPASPRPPPRK 420
P + PT A P + P G PS G+P+PPA+ P P+
Sbjct: 1065 PSPKGGPATPSLKGAPTPPAATPPS------PKGG---PATPSPKGAPMPPAATPPSPKG 1115
Query: 421 DPEASKASPLPFEPWQRTPPS 441
P P TPPS
Sbjct: 1116 GLATPPHKGAPTTP-AATPPS 1135
Score = 30.8 bits (68), Expect = 2.6
Identities = 53/215 (24%), Positives = 67/215 (31%), Gaps = 45/215 (20%)
Query: 241 PDGHRAPAPPQSGSCDHPLLLLEPGNLASSPSMSLASPQPCGLASHEEHRGAAEELASTP 300
P G A PP+ P SP LA+P P +GA A+TP
Sbjct: 1159 PKGGLATPPPKGAPTT-------PAATPPSPKGGLATPSP---------KGAPTTPAATP 1202
Query: 301 NDKASSPGHPAFLEDGSPSPVLAFAASPRPNHSYIFKREPPEGCEKVRVFEEATSPGPDL 360
P+ G+P+ A SP+ P+G AT P P
Sbjct: 1203 PSPKGGLATPS--PKGAPTTPAATPPSPKGG----LATPSPKGAPTTPA---ATPPSPKG 1253
Query: 361 AFLTSCPDKNKVHFNPTGSAFCPVNLMKPLF-------PGMGFIFRNCPSN-------PG 406
T P PT A P +L L P + P G
Sbjct: 1254 GPATPPPKGA-----PTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKG 1308
Query: 407 SPLPPASPRPPPRKDPEASKASPLPFEPWQRTPPS 441
+P PPA+ P P+ P P P TPPS
Sbjct: 1309 APTPPAATPPSPKGSPGTPPPKGAPTPP-AVTPPS 1342
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 41.2 bits (95), Expect = 0.002
Identities = 57/209 (27%), Positives = 75/209 (35%), Gaps = 27/209 (12%)
Query: 248 APPQSGSCDHPLLLLEPGNLASSPSMSLASPQPCGLASHEEHRGAAEELASTPNDKASSP 307
APP + P L + P AS P A+P P AA L P+ AS P
Sbjct: 695 APPSLAA---PPLQVPPSPPASPPMSPSATPPP-----QAPPPLAAPPLQVPPSPPASPP 746
Query: 308 GHPAFLEDGSPSPVLA---FAASPRPNHSYIFK---REPPEGCEKVRVFEEATSPGPDLA 361
P+ P+LA P P S + PP+ + P P +
Sbjct: 747 MSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPAS 806
Query: 362 FLTSCPDKNKVHFNPTGSA-FCPVNLMKPLFPGM--GFIFRNCPSNPGSPLPPASPRPPP 418
F P F+P+ S P+ P P + + + PS P SP A PR PP
Sbjct: 807 FPGQAP------FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA-PRRPP 859
Query: 419 RKDPEASKASP---LPFEPWQRTPPSEEP 444
P+ S + P L P PPS P
Sbjct: 860 TPGPDTSVSGPRLTLALAPGPPPPPSRSP 888
Score = 35.0 bits (79), Expect = 0.14
Identities = 62/238 (26%), Positives = 75/238 (31%), Gaps = 43/238 (18%)
Query: 238 LDIPDGHRAPAPPQSGSCDHPLLLLEPGNLASSPSMSLASPQPCGLASHEEHRG---AAE 294
L P PP++ S P LAS P L SP LA+ A
Sbjct: 569 LQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALP 628
Query: 295 ELASTPNDKASSPGHPAFLEDGSPSP---------VLAFAASPRPNHSYIFKREPPEGCE 345
L + P+ AS P P +PSP +L SP P+ PP
Sbjct: 629 PLQAPPSPPASPPLSPL----ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP 684
Query: 346 KVRVFEEATSPG--------PDLAFLTSCPDKNKVHFNPTGSAFCPVNLMKPLFPGMGFI 397
V AT P P L S P + + T P L P
Sbjct: 685 ---VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL------ 735
Query: 398 FRNCPSNPGSPLPPASPRPPPRKDP---------EASKASPLPFEPWQRTPPSEEPVL 446
+ PS P SP S PPPR P S + LP P + PP P L
Sbjct: 736 -QVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPAL 792
Score = 32.0 bits (71), Expect = 1.2
Identities = 54/213 (25%), Positives = 65/213 (30%), Gaps = 43/213 (20%)
Query: 248 APPQSGSCDHPLLLLEPGNLASSPSMSLASPQPCGLASHEEHRGAAEELASTPNDKASSP 307
+PP S P P + SPS + S P LA A L P+ AS P
Sbjct: 666 SPPPSPPVQAPFS--PPASPPVSPSATPPSQAPPSLA--------APPLQVPPSPPASPP 715
Query: 308 GHPAFLEDGSPSPVLA---FAASPRPNHSYIFKREPPEGCEKVRVFEEATSPGPDLAFLT 364
P+ P LA P P S PP + +P P + L
Sbjct: 716 MSPSATPPPQAPPPLAAPPLQVPPSPPAS------PP--------MSPSATPPPRVPPLL 761
Query: 365 SCPDKNKVHFNPTGSAFCPVNLMKPLFPGMGFIFRNCPSNPGSPLPPASPRP-PPRKDPE 423
+ P P P+ P P P PP P PP P
Sbjct: 762 AAPPLQVPPSPPASLPMSPLAKPPPQAP------------PALATPPLQALPSPPASFPG 809
Query: 424 ASKASP---LPFEPWQRTPPSEEPVLFQSSLMV 453
+ SP LP P PP PVL L V
Sbjct: 810 QAPFSPSASLPMSPLATPPPQAPPVLAAPLLQV 842
>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
Length = 2217
Score = 41.2 bits (95), Expect = 0.002
Identities = 53/218 (24%), Positives = 85/218 (38%), Gaps = 42/218 (19%)
Query: 243 GHRAPAPPQSGSCDHPLLLLEPGNLASSPSMSLASPQPCGLASHEEHRGAAEELASTPND 302
G P P+ D LL P L +S + SLAS ++ + +G+ S +
Sbjct: 582 GQPGPPEPEEPEADQHLL---PPTLPTSAT-SLASD-----STFDSGQGSTVYSDSQSSQ 632
Query: 303 KASSPGHPAFLEDGSPSPVLAFAASPRPNHSYIFKREPPEGCEKVRVFEEATS-PGPDLA 361
++ G L D +PSP + P + P+ + +++ T+ PG +
Sbjct: 633 QSVMLGS---LADAAPSPAQCVCSPPVSEGPVL-----PQSLPSLGAYQQPTAAPGLPVG 684
Query: 362 FLTS--CPDKNKVHFNPTGSAFCPVNLMKPLFPGMGFIFRNCPSNPGSPLPPASPRPPPR 419
+ + CP + HF +F PV + P PS P P P P PP +
Sbjct: 685 SVPAPACPPSLQQHFPDPAMSFAPV--LPP------------PSTP-MPTGPGQPAPPGQ 729
Query: 420 KDPEASKASPL-------PFEPWQRTPPSEEPVLFQSS 450
+ P ++ +PL P P Q PP P L +S
Sbjct: 730 QPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPAS 767
Score = 30.8 bits (68), Expect = 2.6
Identities = 38/163 (23%), Positives = 56/163 (34%), Gaps = 7/163 (4%)
Query: 287 EEHRGAAEELASTPNDKASSPGHPAFL------EDGSPSPVLAFAASPRPNHSYIFKREP 340
E RGA + P KA+ PG FL D P L A +P P +R
Sbjct: 16 EPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAAEAPGPQPPQPLQRRV 75
Query: 341 PEGCEKVRVFEEATSPGPDLAFLTSCPDKNKVHFNPTGSAFCPVNLMKPLFPGMGFIFRN 400
C+ R+ E P + + P + PV +P +
Sbjct: 76 LLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVGTQEPGPDPIAAAVET 135
Query: 401 CPSNPGSPLPPASPRPPPRKDPEASKASPLPFEPWQRTPPSEE 443
P+ G P A+ ++D A++A P P + P EE
Sbjct: 136 APAPDGGPREEAA-ATVRKEDEGAAEAKPEPGRTRRDEPEEEE 177
Score = 30.8 bits (68), Expect = 2.6
Identities = 56/201 (27%), Positives = 70/201 (34%), Gaps = 30/201 (14%)
Query: 244 HRAPAPPQSGSCDHPLLLLEP-GNLASSPSMSLASP--QPCGLASHE--EHRGAAEELAS 298
H AP P+S S PL L P + S+P S QP LAS + G + +
Sbjct: 1321 HPAPEAPES-SPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGA 1379
Query: 299 TPNDKA-SSPGHPAFLEDGSPSPVLAFAASPRPNHSYIFKREPPEGCEKVRVFEEATSPG 357
P A SSP A +DG+ A A S P EP G +A PG
Sbjct: 1380 PPAPLAPSSPPVTALPQDGA-----APATSTMP--------EPASGTAS-----QAGGPG 1421
Query: 358 PDLAFLTSCPDKN---KVHFNPTGSAFCPVNLMKPLFPGMGFIFRNCPSNPGSPLPPASP 414
+ + H P V L P P S P PLPP +P
Sbjct: 1422 TPQGLTSELETSQPLAETHEAPLAVQPLVVGLA-PCTPAPEAASTRDASAPREPLPPPAP 1480
Query: 415 RPPPRK-DPEASKASPLPFEP 434
P P P+ + P P P
Sbjct: 1481 EPSPHSGTPQPALGQPAPLLP 1501
>gi|38201621 eukaryotic translation initiation factor 4 gamma, 1
isoform 1 [Homo sapiens]
Length = 1599
Score = 40.0 bits (92), Expect = 0.004
Identities = 51/204 (25%), Positives = 75/204 (36%), Gaps = 21/204 (10%)
Query: 241 PDGHRAPAPP-QSGSCDHPLLLLEPGNLASSPSMSLASPQPCGLASHEEHRGAAEE--LA 297
P +P+P + GS + +L PG+ ++ MS+ P + E +R + E LA
Sbjct: 262 PSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLA 321
Query: 298 STPNDKASSPGHPAFLEDGSPSPVLAFAASPRPNHSYIFKREPPEGCEKVRVFEEATSPG 357
+ + P + S SP+ A P P S+ + P G E
Sbjct: 322 EPILEVEVTLSKPVPESEFSSSPLQA----PTPLASHTVEIHEPNGMVPSEDLEPEVESS 377
Query: 358 PDLAFLTSCPDKNKVHFNPTGSAFCPVNLMKPLFPGMGFIFRNCPSNPGSPLPPASPRPP 417
P+LA +CP ++ V PT P L+ PS P L P S
Sbjct: 378 PELAPPPACPSESPVPIAPTAQ---PEELL-----------NGAPSPPAVDLSPVSEPEE 423
Query: 418 PRKDPEASKASPLPFEPWQRTPPS 441
K+ AS A P T PS
Sbjct: 424 QAKEVTASMAPPTIPSATPATAPS 447
>gi|38201627 eukaryotic translation initiation factor 4 gamma, 1
isoform 2 [Homo sapiens]
Length = 1512
Score = 40.0 bits (92), Expect = 0.004
Identities = 51/204 (25%), Positives = 75/204 (36%), Gaps = 21/204 (10%)
Query: 241 PDGHRAPAPP-QSGSCDHPLLLLEPGNLASSPSMSLASPQPCGLASHEEHRGAAEE--LA 297
P +P+P + GS + +L PG+ ++ MS+ P + E +R + E LA
Sbjct: 175 PSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLA 234
Query: 298 STPNDKASSPGHPAFLEDGSPSPVLAFAASPRPNHSYIFKREPPEGCEKVRVFEEATSPG 357
+ + P + S SP+ A P P S+ + P G E
Sbjct: 235 EPILEVEVTLSKPVPESEFSSSPLQA----PTPLASHTVEIHEPNGMVPSEDLEPEVESS 290
Query: 358 PDLAFLTSCPDKNKVHFNPTGSAFCPVNLMKPLFPGMGFIFRNCPSNPGSPLPPASPRPP 417
P+LA +CP ++ V PT P L+ PS P L P S
Sbjct: 291 PELAPPPACPSESPVPIAPTAQ---PEELL-----------NGAPSPPAVDLSPVSEPEE 336
Query: 418 PRKDPEASKASPLPFEPWQRTPPS 441
K+ AS A P T PS
Sbjct: 337 QAKEVTASMAPPTIPSATPATAPS 360
>gi|38201625 eukaryotic translation initiation factor 4 gamma, 1
isoform 3 [Homo sapiens]
Length = 1435
Score = 40.0 bits (92), Expect = 0.004
Identities = 51/204 (25%), Positives = 75/204 (36%), Gaps = 21/204 (10%)
Query: 241 PDGHRAPAPP-QSGSCDHPLLLLEPGNLASSPSMSLASPQPCGLASHEEHRGAAEE--LA 297
P +P+P + GS + +L PG+ ++ MS+ P + E +R + E LA
Sbjct: 98 PSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLA 157
Query: 298 STPNDKASSPGHPAFLEDGSPSPVLAFAASPRPNHSYIFKREPPEGCEKVRVFEEATSPG 357
+ + P + S SP+ A P P S+ + P G E
Sbjct: 158 EPILEVEVTLSKPVPESEFSSSPLQA----PTPLASHTVEIHEPNGMVPSEDLEPEVESS 213
Query: 358 PDLAFLTSCPDKNKVHFNPTGSAFCPVNLMKPLFPGMGFIFRNCPSNPGSPLPPASPRPP 417
P+LA +CP ++ V PT P L+ PS P L P S
Sbjct: 214 PELAPPPACPSESPVPIAPTAQ---PEELL-----------NGAPSPPAVDLSPVSEPEE 259
Query: 418 PRKDPEASKASPLPFEPWQRTPPS 441
K+ AS A P T PS
Sbjct: 260 QAKEVTASMAPPTIPSATPATAPS 283
>gi|38201623 eukaryotic translation initiation factor 4 gamma, 1
isoform 1 [Homo sapiens]
Length = 1599
Score = 40.0 bits (92), Expect = 0.004
Identities = 51/204 (25%), Positives = 75/204 (36%), Gaps = 21/204 (10%)
Query: 241 PDGHRAPAPP-QSGSCDHPLLLLEPGNLASSPSMSLASPQPCGLASHEEHRGAAEE--LA 297
P +P+P + GS + +L PG+ ++ MS+ P + E +R + E LA
Sbjct: 262 PSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLA 321
Query: 298 STPNDKASSPGHPAFLEDGSPSPVLAFAASPRPNHSYIFKREPPEGCEKVRVFEEATSPG 357
+ + P + S SP+ A P P S+ + P G E
Sbjct: 322 EPILEVEVTLSKPVPESEFSSSPLQA----PTPLASHTVEIHEPNGMVPSEDLEPEVESS 377
Query: 358 PDLAFLTSCPDKNKVHFNPTGSAFCPVNLMKPLFPGMGFIFRNCPSNPGSPLPPASPRPP 417
P+LA +CP ++ V PT P L+ PS P L P S
Sbjct: 378 PELAPPPACPSESPVPIAPTAQ---PEELL-----------NGAPSPPAVDLSPVSEPEE 423
Query: 418 PRKDPEASKASPLPFEPWQRTPPS 441
K+ AS A P T PS
Sbjct: 424 QAKEVTASMAPPTIPSATPATAPS 447
>gi|38201619 eukaryotic translation initiation factor 4 gamma, 1
isoform 4 [Homo sapiens]
Length = 1403
Score = 40.0 bits (92), Expect = 0.004
Identities = 51/204 (25%), Positives = 75/204 (36%), Gaps = 21/204 (10%)
Query: 241 PDGHRAPAPP-QSGSCDHPLLLLEPGNLASSPSMSLASPQPCGLASHEEHRGAAEE--LA 297
P +P+P + GS + +L PG+ ++ MS+ P + E +R + E LA
Sbjct: 66 PSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLA 125
Query: 298 STPNDKASSPGHPAFLEDGSPSPVLAFAASPRPNHSYIFKREPPEGCEKVRVFEEATSPG 357
+ + P + S SP+ A P P S+ + P G E
Sbjct: 126 EPILEVEVTLSKPVPESEFSSSPLQA----PTPLASHTVEIHEPNGMVPSEDLEPEVESS 181
Query: 358 PDLAFLTSCPDKNKVHFNPTGSAFCPVNLMKPLFPGMGFIFRNCPSNPGSPLPPASPRPP 417
P+LA +CP ++ V PT P L+ PS P L P S
Sbjct: 182 PELAPPPACPSESPVPIAPTAQ---PEELL-----------NGAPSPPAVDLSPVSEPEE 227
Query: 418 PRKDPEASKASPLPFEPWQRTPPS 441
K+ AS A P T PS
Sbjct: 228 QAKEVTASMAPPTIPSATPATAPS 251
>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
Length = 2157
Score = 40.0 bits (92), Expect = 0.004
Identities = 51/185 (27%), Positives = 64/185 (34%), Gaps = 42/185 (22%)
Query: 168 SRSGKEKERGSPLLGDHAVRGALRASPPSFPSGSPVLRLSPCLHRSLEGLNQELEEVFVK 227
SR +E+ G PL PP PS S V RL +H + G+ Q L ++ +
Sbjct: 1440 SRPPEERPPGLPL-------------PPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSR 1486
Query: 228 EQGEEELLRILDIPDGH--RAPAPPQS--GSCDHPLLLLEP----GNLASSPSMSLASPQ 279
+ + P GH P PQ+ G P EP L+S P P
Sbjct: 1487 QGS-------VTAPGGHPRHKPGLPQAPQGPSPRPPTRYEPQRVNSGLSSDPHFEEPGPM 1539
Query: 280 PCGLASHEEHRGAAEELASTPNDKAS-SPGHPAFLEDGSPSPVLAFAASPRPNHSYIFKR 338
G + TP D A SP P E P L S P HS F
Sbjct: 1540 VRG-------------VGGTPRDSAGVSPFPPKRRERPPRKPELLQEESLPPPHSSGFLG 1586
Query: 339 EPPEG 343
PEG
Sbjct: 1587 SKPEG 1591
Score = 30.4 bits (67), Expect = 3.4
Identities = 51/203 (25%), Positives = 74/203 (36%), Gaps = 33/203 (16%)
Query: 243 GHRAPAPPQSGSCDHPLL--LLEPGNLASSPSMSLASP--QPCGLASHEEHRGAAEELAS 298
G P PP + ++ ++P L P + P P GL E R + +S
Sbjct: 709 GRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRE--RSDSGGSSS 766
Query: 299 TPNDKASSPGHPAFLEDGSPSPV-----------LAFAASPRPNHSYIFKREPPEGCEKV 347
P D+ + PA L + PV A A PRP S + R+ + +K
Sbjct: 767 EPFDRHA----PAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPL--RQAADEDDKG 820
Query: 348 RVFEEATSPGPDLAFLTSCPDKNKVHFNPTGSAFCPVNLMKPLFPGMGFIFRNCPSNPGS 407
E P P +L S P F G+ P++ PG R P PGS
Sbjct: 821 MRSETPPVPPPP-PYLASYPG-----FPENGAPGPPISRFPLEEPGP----RPLPWPPGS 870
Query: 408 PLPPASPRPPPRKDPEASKASPL 430
PPP+K+P + + L
Sbjct: 871 DEVAKIQTPPPKKEPPKEETAQL 893
Score = 29.6 bits (65), Expect = 5.9
Identities = 20/66 (30%), Positives = 28/66 (42%), Gaps = 20/66 (30%)
Query: 403 SNPGSPLPPASPR-------PPPRKDPEASKA------------SPLPFEP-WQRTPPSE 442
S P +P+PP+ P+ P P+ P KA P+ F+P W PP
Sbjct: 671 SAPPTPVPPSPPQPVTLGAVPAPQAPPPPPKALYPGALGRPPPMPPMNFDPRWMMIPPYV 730
Query: 443 EPVLFQ 448
+P L Q
Sbjct: 731 DPRLLQ 736
>gi|113421234 PREDICTED: similar to NG5 protein [Homo sapiens]
Length = 288
Score = 39.7 bits (91), Expect = 0.006
Identities = 48/174 (27%), Positives = 63/174 (36%), Gaps = 19/174 (10%)
Query: 264 PGNLASSPSMSLASPQPCGL---ASHEEHRGAAEELASTPNDKASSPGHPAFLEDGSPSP 320
P L PS P P G+ S + +G +TP D S P PA ED
Sbjct: 30 PQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSP--ATPEDPRS-PAKPAAPEDPQMPA 86
Query: 321 VLAFAASPRPNHSYIFKREPPEGCEKVRVFEEATSPGPDLAFLTSCPDKNKVHFNPTGSA 380
A PR + E E V + A P + F+ P + P
Sbjct: 87 QPALPQLPRRPRTL---DEDGAAGEAGPVSKAAAGGAPHIGFVGEPPP-----YAPPDPK 138
Query: 381 FCPVNLMKPLFPGMGFIFRNCPSN---PGSPLPPASPRPPPRKDPEASKASPLP 431
P L+ P FP + + + PS P + L PA+P PP P A A P P
Sbjct: 139 AAP--LLYPPFPQVPVVLQPAPSALFPPPAQLYPAAPTPPALFSPPAGAAFPFP 190
>gi|113420954 PREDICTED: similar to NG5 protein [Homo sapiens]
Length = 288
Score = 39.7 bits (91), Expect = 0.006
Identities = 48/174 (27%), Positives = 63/174 (36%), Gaps = 19/174 (10%)
Query: 264 PGNLASSPSMSLASPQPCGL---ASHEEHRGAAEELASTPNDKASSPGHPAFLEDGSPSP 320
P L PS P P G+ S + +G +TP D S P PA ED
Sbjct: 30 PQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSP--ATPEDPRS-PAKPAAPEDPQMPA 86
Query: 321 VLAFAASPRPNHSYIFKREPPEGCEKVRVFEEATSPGPDLAFLTSCPDKNKVHFNPTGSA 380
A PR + E E V + A P + F+ P + P
Sbjct: 87 QPALPQLPRRPRTL---DEDGAAGEAGPVSKAAAGGAPHIGFVGEPPP-----YAPPDPK 138
Query: 381 FCPVNLMKPLFPGMGFIFRNCPSN---PGSPLPPASPRPPPRKDPEASKASPLP 431
P L+ P FP + + + PS P + L PA+P PP P A A P P
Sbjct: 139 AAP--LLYPPFPQVPVVLQPAPSALFPPPAQLYPAAPTPPALFSPPAGAAFPFP 190
>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sapiens]
Length = 2462
Score = 39.7 bits (91), Expect = 0.006
Identities = 37/123 (30%), Positives = 56/123 (45%), Gaps = 12/123 (9%)
Query: 118 DKATQTPLSWQELE----GERASSCAHK-----RSASWGSTDHRKEISKLKQQLQRTKLS 168
+K P S QELE G SS + + S S H K + K ++L ++ L
Sbjct: 2015 EKTQSKPFSIQELELRSLGYHGSSYSPEGVEPVSPVSSPSLTHDKGLPKHLEELDKSHLE 2074
Query: 169 RSGKEKERGSPLLGDHAVR-GALRASPPSFPSGSPVLRLSPCL--HRSLEGLNQELEEVF 225
+ K+ G LG A LR P S PS SP+L+ +P + H+ + L Q + EV
Sbjct: 2075 GELRPKQPGPVKLGGEAAHLPHLRPLPESQPSSSPLLQTAPGVKGHQRVVTLAQHISEVI 2134
Query: 226 VKE 228
++
Sbjct: 2135 TQD 2137
Score = 30.0 bits (66), Expect = 4.5
Identities = 15/40 (37%), Positives = 18/40 (45%)
Query: 405 PGSPLPPASPRPPPRKDPEASKASPLPFEPWQRTPPSEEP 444
PG P PP P P + AS+A+ P P PS P
Sbjct: 763 PGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPP 802
>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sapiens]
Length = 2524
Score = 39.7 bits (91), Expect = 0.006
Identities = 37/123 (30%), Positives = 56/123 (45%), Gaps = 12/123 (9%)
Query: 118 DKATQTPLSWQELE----GERASSCAHK-----RSASWGSTDHRKEISKLKQQLQRTKLS 168
+K P S QELE G SS + + S S H K + K ++L ++ L
Sbjct: 2031 EKTQSKPFSIQELELRSLGYHGSSYSPEGVEPVSPVSSPSLTHDKGLPKHLEELDKSHLE 2090
Query: 169 RSGKEKERGSPLLGDHAVR-GALRASPPSFPSGSPVLRLSPCL--HRSLEGLNQELEEVF 225
+ K+ G LG A LR P S PS SP+L+ +P + H+ + L Q + EV
Sbjct: 2091 GELRPKQPGPVKLGGEAAHLPHLRPLPESQPSSSPLLQTAPGVKGHQRVVTLAQHISEVI 2150
Query: 226 VKE 228
++
Sbjct: 2151 TQD 2153
Score = 30.0 bits (66), Expect = 4.5
Identities = 15/40 (37%), Positives = 18/40 (45%)
Query: 405 PGSPLPPASPRPPPRKDPEASKASPLPFEPWQRTPPSEEP 444
PG P PP P P + AS+A+ P P PS P
Sbjct: 780 PGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPP 819
>gi|153945734 teashirt zinc finger homeobox 2 [Homo sapiens]
Length = 1034
Score = 39.3 bits (90), Expect = 0.007
Identities = 61/252 (24%), Positives = 90/252 (35%), Gaps = 34/252 (13%)
Query: 116 TNDKATQTPLSWQELEGERASSCAHKRSASWGSTDHRKEISK--LKQQLQRTKLSRSGKE 173
+ DK +E E ASS +H S+ ++ E K L + KL + G E
Sbjct: 604 SEDKDEAVKECGKESPHEEASSFSHSEGDSFRKSETPPEAKKTELGPLKEEEKLMKEGSE 663
Query: 174 KERGSPLLGDHAVRG--ALRASPPSFPSGSPVLRLSPCLHRSLEGLNQELEEVFVKEQGE 231
KE+ PL A+ AL P+ P +P+ L L+ L + L
Sbjct: 664 KEKPQPLEPTSALSNGCALANHAPALPCINPLSALQSVLNNHLGKATEPLRSPSCSSPSS 723
Query: 232 EEL-------LRILDIPDGHRAPAPPQSGSCDHPLLLLEPGNLASSPSMSLASPQPCGLA 284
+ L ++D P +PA +S S L S QP L
Sbjct: 724 STISMFHKSNLNVMDKP--VLSPASTRSASVSRRYLFEN-------------SDQPIDLT 768
Query: 285 SHEEHRGAAEELASTPNDKASSPGHPAFLEDGSPSPVLAFAASPRPNHSYIFKREPPEGC 344
+ + + + S S P A + VL A +P+P S R PP
Sbjct: 769 KSKSKKAESSQAQSC----MSPPQKHALSDIADMVKVLPKATTPKPASS---SRVPPMKL 821
Query: 345 E-KVRVFEEATS 355
E VR FE+ +S
Sbjct: 822 EMDVRRFEDVSS 833
>gi|50409738 SRp25 nuclear protein isoform 3 [Homo sapiens]
Length = 352
Score = 38.9 bits (89), Expect = 0.010
Identities = 53/190 (27%), Positives = 75/190 (39%), Gaps = 22/190 (11%)
Query: 1 MAGAAAGGRGGGAWGPGRGGAGGLRRGCSPPAPAGSPRAGLQPLRATIPFQLQQPHQRRD 60
+A A G G WG G+G P PA RA +P ++ P L++
Sbjct: 60 LASAGGGRARDGTWGVRTKGSGA----ALPSRPAS--RAAPRPEASSPPLPLEKARGGLS 113
Query: 61 G--GGRAASVPCSVAPEK-----SVCRPQPLQVRRTFSL-DT---ILSSYLLGQWPRDAD 109
G GGRA V K S R + + R+ S DT +S G+ A
Sbjct: 114 GPQGGRARGAMAHVGSRKRSRSRSRSRGRGSEKRKKKSRKDTSRNCSASTSQGRKASTAP 173
Query: 110 GAFTCCTNDKATQTPLSWQELEGERASSCAHKRSASWGSTDHRKEISKL-----KQQLQR 164
GA +T S +SS + S+S S+D RK+ K K++ +R
Sbjct: 174 GAEERSKQKARRRTRSSSSSSSSSSSSSSSSSSSSSSSSSDGRKKRGKYKDKRRKKKKKR 233
Query: 165 TKLSRSGKEK 174
KL + GKEK
Sbjct: 234 KKLKKKGKEK 243
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 38.5 bits (88), Expect = 0.013
Identities = 23/50 (46%), Positives = 26/50 (52%), Gaps = 4/50 (8%)
Query: 2 AGAAAGGRG----GGAWGPGRGGAGGLRRGCSPPAPAGSPRAGLQPLRAT 47
AGA GG G GG G G GG GG G PP G +AG+ LR+T
Sbjct: 65 AGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRST 114
Score = 30.8 bits (68), Expect = 2.6
Identities = 59/229 (25%), Positives = 72/229 (31%), Gaps = 54/229 (23%)
Query: 241 PDGHRAPAP-PQSGSCDH---PLLLLEPGNLASSPSMSLASPQPCGLASHEE-------- 288
P +R P P P GS P + P + SSP + P P G
Sbjct: 164 PQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFP 223
Query: 289 -HRGAAEELASTPNDKASSPGHPAFLEDGSPSPVLAFAASPRPNHSYIFKREPPEGCEKV 347
+RG A S SS + P+P A P P PP +
Sbjct: 224 GNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPP--------PPPPVGNRP 275
Query: 348 RVFEEATSPGPDLAFLTSCPDKNKVHFNPTGSAFCPVNLMKPLFPGMGFIFRNCPSNPGS 407
+ EA P P P NK T P P PS PG
Sbjct: 276 SIHREAVPPPP--------PQNNKPPVPSTPRPSASSQAPPPPPP---------PSRPGP 318
Query: 408 P-LPPAS------PRPPPRKD---------PEASKASPLPFEPWQRTPP 440
P LPP+S PR P R P ++ PLP P +R PP
Sbjct: 319 PPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPP 367
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 38.5 bits (88), Expect = 0.013
Identities = 23/50 (46%), Positives = 26/50 (52%), Gaps = 4/50 (8%)
Query: 2 AGAAAGGRG----GGAWGPGRGGAGGLRRGCSPPAPAGSPRAGLQPLRAT 47
AGA GG G GG G G GG GG G PP G +AG+ LR+T
Sbjct: 65 AGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRST 114
Score = 30.8 bits (68), Expect = 2.6
Identities = 59/229 (25%), Positives = 72/229 (31%), Gaps = 54/229 (23%)
Query: 241 PDGHRAPAP-PQSGSCDH---PLLLLEPGNLASSPSMSLASPQPCGLASHEE-------- 288
P +R P P P GS P + P + SSP + P P G
Sbjct: 164 PQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFP 223
Query: 289 -HRGAAEELASTPNDKASSPGHPAFLEDGSPSPVLAFAASPRPNHSYIFKREPPEGCEKV 347
+RG A S SS + P+P A P P PP +
Sbjct: 224 GNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPP--------PPPPVGNRP 275
Query: 348 RVFEEATSPGPDLAFLTSCPDKNKVHFNPTGSAFCPVNLMKPLFPGMGFIFRNCPSNPGS 407
+ EA P P P NK T P P PS PG
Sbjct: 276 SIHREAVPPPP--------PQNNKPPVPSTPRPSASSQAPPPPPP---------PSRPGP 318
Query: 408 P-LPPAS------PRPPPRKD---------PEASKASPLPFEPWQRTPP 440
P LPP+S PR P R P ++ PLP P +R PP
Sbjct: 319 PPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPP 367
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 38.5 bits (88), Expect = 0.013
Identities = 49/217 (22%), Positives = 73/217 (33%), Gaps = 30/217 (13%)
Query: 241 PDGHRAPAPPQSGSCDHPLLLLEPGNLASSPSMSLASPQP----CGLASHEEHRGAAEEL 296
P G P Q G+ P+ +P P+ L +P G + + L
Sbjct: 335 PSGLTKPLAQQPGTVKPPV---QPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKAL 391
Query: 297 ASTPN-----DKASSPGHPAFLEDGSPSPVLAFAASPRPNHSYIFKREPPEGCEKVRVFE 351
A P + P P + G+P P+ P + + P + ++
Sbjct: 392 AQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPA 451
Query: 352 EATSPGPDLAFLTSCPDKNKVHFNPTGSAFCPVNLMKPLFPGMGFIFRNCPSNPGSPLPP 411
+ PG A T K G A P P P P PGS PP
Sbjct: 452 QQAGPGKTSAQQTG---PTKPPSQLPGPAKPPPQQPGPAKPP--------PQQPGSAKPP 500
Query: 412 A----SPRPPPRKDPEASKASPLPFEPWQRTPPSEEP 444
+ S +PPP+ + A P P +P PPS++P
Sbjct: 501 SQQPGSTKPPPQ---QPGPAKPSPQQPGSTKPPSQQP 534
Score = 31.2 bits (69), Expect = 2.0
Identities = 82/374 (21%), Positives = 126/374 (33%), Gaps = 75/374 (20%)
Query: 94 TILSSYLLGQWPRDADGAFTCCTNDKATQTPLSWQELEGERASSCAHKRSASWGSTDHRK 153
++ SS L G D+ + T D S +E+E E TD+ +
Sbjct: 2105 SLTSSVLSGASLTDSTSSATLSIPDVKITQHFSTEEIEDEYV-------------TDYTR 2151
Query: 154 EISKLKQQLQRTKLSRSGKEKERGSPLLGDHAVRGALRASPPSFPSGSPVLRLSPCLHRS 213
EI ++ E P ++ ++ +S + S SP+ L S
Sbjct: 2152 EIQEIIAHESLILTYSEPSESATSVPPSDTPSLTSSV-SSVCTTDSSSPITTLD-----S 2205
Query: 214 LEGLNQELEEVFVKEQGEEELLR-------ILDIPDG-----HRAPAPPQSGSCDHPLLL 261
+ + E ++ K + EE+ I+D P+ R P S DH ++
Sbjct: 2206 ITTVYTEPVDMITKFEDSEEISSSTYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVIS 2265
Query: 262 LEP--------------GNLASSPSMSL--ASPQPCGLASHEEHRGAAEELASTPNDKA- 304
L G +A + S L + P A E G E+ DK
Sbjct: 2266 LSDMASSIIESVVPKPEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKE 2325
Query: 305 -------SSPGHPAFLEDGSPSPVLAFAASPRPNHSYIFKREPPEGCEKVRVFEEATSPG 357
SS F D PS V+A + + +Y E G EK + SP
Sbjct: 2326 LEAERTKSSLSETVF--DHPPSSVIALPMKEQLSTTYFTSGET-FGQEKPASQLPSGSPS 2382
Query: 358 PDLAFLTSCPDKNKVHFNPTGSAFCPVNLMKPLFPGMGFIFRNCPSNPGSPLPPASPRPP 417
++S P K + F S+ ++ P P P P P PP P PP
Sbjct: 2383 -----VSSLPAKPRPFFR---SSSLDISAQPPPPP---------PPPPPPPPPPPPPPPP 2425
Query: 418 PRKDPEASKASPLP 431
P P + K + LP
Sbjct: 2426 PLPPPTSPKPTILP 2439
Score = 30.0 bits (66), Expect = 4.5
Identities = 46/206 (22%), Positives = 74/206 (35%), Gaps = 31/206 (15%)
Query: 245 RAPAPPQSGSCDHPLLLLEPGNLASSPSMSLASPQPCGLASHEEHRGAAEELASTPNDKA 304
+A PP++ S P EP + +A +P + ++T
Sbjct: 719 KAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDI 778
Query: 305 SSPGHPAFLEDGSPSPVLAFAASPRPNHSYIFKREPPEGCEKVRVFEEATSPGP--DLAF 362
S + E+ + P+ +A +P+ S+ PP G EKV F+ P P D
Sbjct: 779 PSSKVQSQAEEKTTPPLKTDSA--KPSQSF-----PPTG-EKVSPFDSKAIPRPASDSKI 830
Query: 363 LT----SCPDKNKVHFNPTGSAFCPVNLMKPLFPGMGFIFRNCPSNPGSPLPPASPRPP- 417
++ S K + +P P + P P+P SP PP
Sbjct: 831 ISHPGPSSESKGQKQVDPVQKKEEPKKAQTKM----------SPKPDAKPMPKGSPTPPG 880
Query: 418 PRKDPEASKASPLPFEPWQRTPPSEE 443
PR P A + P P Q++P +E
Sbjct: 881 PR--PTAGQTVPTP----QQSPKPQE 900
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 38.5 bits (88), Expect = 0.013
Identities = 49/217 (22%), Positives = 73/217 (33%), Gaps = 30/217 (13%)
Query: 241 PDGHRAPAPPQSGSCDHPLLLLEPGNLASSPSMSLASPQP----CGLASHEEHRGAAEEL 296
P G P Q G+ P+ +P P+ L +P G + + L
Sbjct: 335 PSGLTKPLAQQPGTVKPPV---QPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKAL 391
Query: 297 ASTPN-----DKASSPGHPAFLEDGSPSPVLAFAASPRPNHSYIFKREPPEGCEKVRVFE 351
A P + P P + G+P P+ P + + P + ++
Sbjct: 392 AQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPA 451
Query: 352 EATSPGPDLAFLTSCPDKNKVHFNPTGSAFCPVNLMKPLFPGMGFIFRNCPSNPGSPLPP 411
+ PG A T K G A P P P P PGS PP
Sbjct: 452 QQAGPGKTSAQQTG---PTKPPSQLPGPAKPPPQQPGPAKPP--------PQQPGSAKPP 500
Query: 412 A----SPRPPPRKDPEASKASPLPFEPWQRTPPSEEP 444
+ S +PPP+ + A P P +P PPS++P
Sbjct: 501 SQQPGSTKPPPQ---QPGPAKPSPQQPGSTKPPSQQP 534
Score = 31.2 bits (69), Expect = 2.0
Identities = 82/374 (21%), Positives = 126/374 (33%), Gaps = 75/374 (20%)
Query: 94 TILSSYLLGQWPRDADGAFTCCTNDKATQTPLSWQELEGERASSCAHKRSASWGSTDHRK 153
++ SS L G D+ + T D S +E+E E TD+ +
Sbjct: 2105 SLTSSVLSGASLTDSTSSATLSIPDVKITQHFSTEEIEDEYV-------------TDYTR 2151
Query: 154 EISKLKQQLQRTKLSRSGKEKERGSPLLGDHAVRGALRASPPSFPSGSPVLRLSPCLHRS 213
EI ++ E P ++ ++ +S + S SP+ L S
Sbjct: 2152 EIQEIIAHESLILTYSEPSESATSVPPSDTPSLTSSV-SSVCTTDSSSPITTLD-----S 2205
Query: 214 LEGLNQELEEVFVKEQGEEELLR-------ILDIPDG-----HRAPAPPQSGSCDHPLLL 261
+ + E ++ K + EE+ I+D P+ R P S DH ++
Sbjct: 2206 ITTVYTEPVDMITKFEDSEEISSSTYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVIS 2265
Query: 262 LEP--------------GNLASSPSMSL--ASPQPCGLASHEEHRGAAEELASTPNDKA- 304
L G +A + S L + P A E G E+ DK
Sbjct: 2266 LSDMASSIIESVVPKPEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKE 2325
Query: 305 -------SSPGHPAFLEDGSPSPVLAFAASPRPNHSYIFKREPPEGCEKVRVFEEATSPG 357
SS F D PS V+A + + +Y E G EK + SP
Sbjct: 2326 LEAERTKSSLSETVF--DHPPSSVIALPMKEQLSTTYFTSGET-FGQEKPASQLPSGSPS 2382
Query: 358 PDLAFLTSCPDKNKVHFNPTGSAFCPVNLMKPLFPGMGFIFRNCPSNPGSPLPPASPRPP 417
++S P K + F S+ ++ P P P P P PP P PP
Sbjct: 2383 -----VSSLPAKPRPFFR---SSSLDISAQPPPPP---------PPPPPPPPPPPPPPPP 2425
Query: 418 PRKDPEASKASPLP 431
P P + K + LP
Sbjct: 2426 PLPPPTSPKPTILP 2439
Score = 30.0 bits (66), Expect = 4.5
Identities = 46/206 (22%), Positives = 74/206 (35%), Gaps = 31/206 (15%)
Query: 245 RAPAPPQSGSCDHPLLLLEPGNLASSPSMSLASPQPCGLASHEEHRGAAEELASTPNDKA 304
+A PP++ S P EP + +A +P + ++T
Sbjct: 719 KAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDI 778
Query: 305 SSPGHPAFLEDGSPSPVLAFAASPRPNHSYIFKREPPEGCEKVRVFEEATSPGP--DLAF 362
S + E+ + P+ +A +P+ S+ PP G EKV F+ P P D
Sbjct: 779 PSSKVQSQAEEKTTPPLKTDSA--KPSQSF-----PPTG-EKVSPFDSKAIPRPASDSKI 830
Query: 363 LT----SCPDKNKVHFNPTGSAFCPVNLMKPLFPGMGFIFRNCPSNPGSPLPPASPRPP- 417
++ S K + +P P + P P+P SP PP
Sbjct: 831 ISHPGPSSESKGQKQVDPVQKKEEPKKAQTKM----------SPKPDAKPMPKGSPTPPG 880
Query: 418 PRKDPEASKASPLPFEPWQRTPPSEE 443
PR P A + P P Q++P +E
Sbjct: 881 PR--PTAGQTVPTP----QQSPKPQE 900
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.133 0.418
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,977,923
Number of Sequences: 37866
Number of extensions: 1639800
Number of successful extensions: 16635
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 171
Number of HSP's successfully gapped in prelim test: 496
Number of HSP's that attempted gapping in prelim test: 12548
Number of HSP's gapped (non-prelim): 3745
length of query: 453
length of database: 18,247,518
effective HSP length: 106
effective length of query: 347
effective length of database: 14,233,722
effective search space: 4939101534
effective search space used: 4939101534
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.