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Search of human proteins with 60685227
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|60685227 SECIS binding protein 2-like [Homo sapiens]
(1056 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|60685227 SECIS binding protein 2-like [Homo sapiens] 2100 0.0
gi|83779010 SECIS binding protein 2 [Homo sapiens] 313 5e-85
gi|21735415 centromere protein B [Homo sapiens] 45 4e-04
gi|38327039 heat shock 70kDa protein 4 [Homo sapiens] 45 5e-04
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 44 6e-04
gi|52487176 tripartite motif-containing 37 protein [Homo sapiens] 44 0.001
gi|15147333 tripartite motif-containing 37 protein [Homo sapiens] 44 0.001
gi|157674363 protein phosphatase 1, regulatory subunit 15A [Homo... 42 0.002
gi|95147342 chromodomain helicase DNA binding protein 9 [Homo sa... 42 0.004
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 42 0.004
gi|79750944 ubiquitin specific peptidase 42 [Homo sapiens] 41 0.005
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 40 0.012
gi|33598960 alpha-2B-adrenergic receptor [Homo sapiens] 39 0.020
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 39 0.020
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 39 0.020
gi|38016156 hypothetical protein LOC55345 [Homo sapiens] 39 0.026
gi|82830424 gon-4-like isoform a [Homo sapiens] 39 0.034
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 38 0.044
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 38 0.044
gi|20336305 B-cell CLL/lymphoma 11A isoform 1 [Homo sapiens] 38 0.044
gi|20336307 B-cell CLL/lymphoma 11A isoform 2 [Homo sapiens] 38 0.044
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 38 0.044
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 38 0.044
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 38 0.044
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 38 0.044
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 38 0.044
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 38 0.044
gi|18093112 ABT1-associated protein [Homo sapiens] 38 0.044
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 38 0.058
gi|38788260 bromodomain PHD finger transcription factor isoform ... 38 0.058
>gi|60685227 SECIS binding protein 2-like [Homo sapiens]
Length = 1056
Score = 2100 bits (5442), Expect = 0.0
Identities = 1056/1056 (100%), Positives = 1056/1056 (100%)
Query: 1 MDRAPTEQNVKLSAEVEPFIPQKKSPDTFMIPMALPNDNGSVSGVEPTPIPSYLITCYPF 60
MDRAPTEQNVKLSAEVEPFIPQKKSPDTFMIPMALPNDNGSVSGVEPTPIPSYLITCYPF
Sbjct: 1 MDRAPTEQNVKLSAEVEPFIPQKKSPDTFMIPMALPNDNGSVSGVEPTPIPSYLITCYPF 60
Query: 61 VQENQSNRQFPLYNNDIRWQQPNPNPTGPYFAYPIISAQPPVSTEYTYYQLMPAPCAQVM 120
VQENQSNRQFPLYNNDIRWQQPNPNPTGPYFAYPIISAQPPVSTEYTYYQLMPAPCAQVM
Sbjct: 61 VQENQSNRQFPLYNNDIRWQQPNPNPTGPYFAYPIISAQPPVSTEYTYYQLMPAPCAQVM 120
Query: 121 GFYHPFPTPYSNTFQAANTVNAITTECTERPSQLGQVFPLSSHRSRNSNRGSVVPKQQLL 180
GFYHPFPTPYSNTFQAANTVNAITTECTERPSQLGQVFPLSSHRSRNSNRGSVVPKQQLL
Sbjct: 121 GFYHPFPTPYSNTFQAANTVNAITTECTERPSQLGQVFPLSSHRSRNSNRGSVVPKQQLL 180
Query: 181 QQHIKSKRPLVKNVATQKETNAAGPDSRSKIVLLVDASQQTDFPSDIANKSLSETTATML 240
QQHIKSKRPLVKNVATQKETNAAGPDSRSKIVLLVDASQQTDFPSDIANKSLSETTATML
Sbjct: 181 QQHIKSKRPLVKNVATQKETNAAGPDSRSKIVLLVDASQQTDFPSDIANKSLSETTATML 240
Query: 241 WKSKGRRRRASHPTAESSSEQGASEADIDSDSGYCSPKHSNNQPAAGALRNPDSGTMNHV 300
WKSKGRRRRASHPTAESSSEQGASEADIDSDSGYCSPKHSNNQPAAGALRNPDSGTMNHV
Sbjct: 241 WKSKGRRRRASHPTAESSSEQGASEADIDSDSGYCSPKHSNNQPAAGALRNPDSGTMNHV 300
Query: 301 ESSMCAGGVNWSNVTCQATQKKPWMEKNQTFSRGGRQTEQRNNSQDEDGFQELNENGNAK 360
ESSMCAGGVNWSNVTCQATQKKPWMEKNQTFSRGGRQTEQRNNSQDEDGFQELNENGNAK
Sbjct: 301 ESSMCAGGVNWSNVTCQATQKKPWMEKNQTFSRGGRQTEQRNNSQDEDGFQELNENGNAK 360
Query: 361 DENIQQKLSSKVLDDLPENSPINIVQTPIPITTSVPKRAKSQKKKALAAALATAQEYSEI 420
DENIQQKLSSKVLDDLPENSPINIVQTPIPITTSVPKRAKSQKKKALAAALATAQEYSEI
Sbjct: 361 DENIQQKLSSKVLDDLPENSPINIVQTPIPITTSVPKRAKSQKKKALAAALATAQEYSEI 420
Query: 421 SMEQKKLQEALSKAAGKKNKTPVQLDLGDMLAALEKQQQAMKARQITNTRPLSYTVVTAA 480
SMEQKKLQEALSKAAGKKNKTPVQLDLGDMLAALEKQQQAMKARQITNTRPLSYTVVTAA
Sbjct: 421 SMEQKKLQEALSKAAGKKNKTPVQLDLGDMLAALEKQQQAMKARQITNTRPLSYTVVTAA 480
Query: 481 SFHTKDSTNRKPLTKSQPCLTSFNSVDIASSKAKKGKEKEIAKLKRPTALKKVILKEREE 540
SFHTKDSTNRKPLTKSQPCLTSFNSVDIASSKAKKGKEKEIAKLKRPTALKKVILKEREE
Sbjct: 481 SFHTKDSTNRKPLTKSQPCLTSFNSVDIASSKAKKGKEKEIAKLKRPTALKKVILKEREE 540
Query: 541 KKGRLTVDHNLLGSEEPTEMHLDFIDDLPQEIVSQEDTGLSMPSDTSLSPASQNSPYCMT 600
KKGRLTVDHNLLGSEEPTEMHLDFIDDLPQEIVSQEDTGLSMPSDTSLSPASQNSPYCMT
Sbjct: 541 KKGRLTVDHNLLGSEEPTEMHLDFIDDLPQEIVSQEDTGLSMPSDTSLSPASQNSPYCMT 600
Query: 601 PVSQGSPASSGIGSPMASSTITKIHSKRFREYCNQVLCKEIDECVTLLLQELVSFQERIY 660
PVSQGSPASSGIGSPMASSTITKIHSKRFREYCNQVLCKEIDECVTLLLQELVSFQERIY
Sbjct: 601 PVSQGSPASSGIGSPMASSTITKIHSKRFREYCNQVLCKEIDECVTLLLQELVSFQERIY 660
Query: 661 QKDPVRAKARRRLVMGLREVTKHMKLNKIKCVIISPNCEKIQSKGGLDEALYNVIAMARE 720
QKDPVRAKARRRLVMGLREVTKHMKLNKIKCVIISPNCEKIQSKGGLDEALYNVIAMARE
Sbjct: 661 QKDPVRAKARRRLVMGLREVTKHMKLNKIKCVIISPNCEKIQSKGGLDEALYNVIAMARE 720
Query: 721 QEIPFVFALGRKALGRCVNKLVPVSVVGIFNYFGAESLFNKLVELTEEARKAYKDMVAAM 780
QEIPFVFALGRKALGRCVNKLVPVSVVGIFNYFGAESLFNKLVELTEEARKAYKDMVAAM
Sbjct: 721 QEIPFVFALGRKALGRCVNKLVPVSVVGIFNYFGAESLFNKLVELTEEARKAYKDMVAAM 780
Query: 781 EQEQAEEALKNVKKVPHHMGHSRNPSAASAISFCSVISEPISEVNEKEYETNWRNMVETS 840
EQEQAEEALKNVKKVPHHMGHSRNPSAASAISFCSVISEPISEVNEKEYETNWRNMVETS
Sbjct: 781 EQEQAEEALKNVKKVPHHMGHSRNPSAASAISFCSVISEPISEVNEKEYETNWRNMVETS 840
Query: 841 DGLEASENEKEVSCKHSTSEKPSKLPFDTPPIGKQPSLVATGSTTSATSAGKSTASDKEE 900
DGLEASENEKEVSCKHSTSEKPSKLPFDTPPIGKQPSLVATGSTTSATSAGKSTASDKEE
Sbjct: 841 DGLEASENEKEVSCKHSTSEKPSKLPFDTPPIGKQPSLVATGSTTSATSAGKSTASDKEE 900
Query: 901 VKPDDLEWASQQSTETGSLDGSCRDLLNSSITSTTSTLVPGMLEEEEDEDEEEEEDYTHE 960
VKPDDLEWASQQSTETGSLDGSCRDLLNSSITSTTSTLVPGMLEEEEDEDEEEEEDYTHE
Sbjct: 901 VKPDDLEWASQQSTETGSLDGSCRDLLNSSITSTTSTLVPGMLEEEEDEDEEEEEDYTHE 960
Query: 961 PISVEVQLNSRIESWVSETQRTMETLQLGKTLNGSEEDNVEQSGEEEAEAPEVLEPGMDS 1020
PISVEVQLNSRIESWVSETQRTMETLQLGKTLNGSEEDNVEQSGEEEAEAPEVLEPGMDS
Sbjct: 961 PISVEVQLNSRIESWVSETQRTMETLQLGKTLNGSEEDNVEQSGEEEAEAPEVLEPGMDS 1020
Query: 1021 EAWTADQQASPGQQKSSNCSSLNKEHSDSNYTTQTT 1056
EAWTADQQASPGQQKSSNCSSLNKEHSDSNYTTQTT
Sbjct: 1021 EAWTADQQASPGQQKSSNCSSLNKEHSDSNYTTQTT 1056
>gi|83779010 SECIS binding protein 2 [Homo sapiens]
Length = 854
Score = 313 bits (802), Expect = 5e-85
Identities = 267/899 (29%), Positives = 410/899 (45%), Gaps = 98/899 (10%)
Query: 3 RAPTEQNVKLSAEVEPFIPQKKSPDTFMIPMALPNDNGSVSGVEPTPIPSYLITCYPFVQ 62
R P + +KLSA+V+PF+P+ + + + E PS T YPFVQ
Sbjct: 7 REPESEGIKLSADVKPFVPRFAGLNVAWLESS-----------EACVFPSSAATYYPFVQ 55
Query: 63 ENQSNRQFPLYNNDIRWQQPNPNPTGPYFAYPIISAQPPVSTEYTY---YQLMPAPCAQV 119
E Q +Y D+ + + P + I+ P + YT + P +Q
Sbjct: 56 EPPVTEQ-KIYTEDMAF---GASTFPPQYLSSEITLHPYAYSPYTLDSTQNVYSVPGSQY 111
Query: 120 M----GFYHPFPTPY---SNTFQAANTVNAITTECTERPSQLGQVFPLSSHRS------- 165
+ Y F T NT + A+ + T + S R+
Sbjct: 112 LYNQPSCYRGFQTVKHRNENTCPLPQEMKALFKKKTYDEKKTYDQQKFDSERADGTISSE 171
Query: 166 ----RNSNRGSVVPKQQLLQQHI-----KSKRPLVKNVATQKE----TNAAGPDSRSKIV 212
R S+ S+ + L + R + KNV+T K T P+ +
Sbjct: 172 IKSARGSHHLSIYAENSLKSDGYHKRTDRKSRIIAKNVSTSKPEFEFTTLDFPELQGAEN 231
Query: 213 LLVDASQQTDF------PSDIANKSLSETTATMLWKSKGRRRRASHPTAESSSEQGASEA 266
+ + +Q + +DI+ L E SKG ++P ++ +
Sbjct: 232 NMSEIQKQPKWGPVHSVSTDIS--LLREVVKPAAVLSKGEIVVKNNPNESVTANAATNSP 289
Query: 267 DIDSDSGYCSPKHSNNQPAAGALRNPDSGTMNHVESSMCAGGVNWSNVTCQATQKKPWME 326
+ + + Q + L + + A + NV+ +++ +
Sbjct: 290 SCTRELSWTPMGYVVRQTLSTELSAAPKNVTSMINLKTIASSADPKNVSIPSSEA---LS 346
Query: 327 KNQTFSRGGRQTEQRNNSQDEDGFQELNENGNAKDENIQQKLSSKVLDDLPENSPINIVQ 386
+ ++++ S+ G + K++ ++K +SK + VQ
Sbjct: 347 SDPSYNKEKHIIHPTQKSKASQGSDLEQNEASRKNKKKKEKSTSKY--------EVLTVQ 398
Query: 387 TPIPITTSVPKRAKSQKKKALAAALATAQEYSEISMEQKKLQEALSKAAGKKNKTPVQLD 446
P P+ +++ LA A + K+ + K KK++ PVQLD
Sbjct: 399 EP-------PRIEDAEEFPNLAVASERRDRIETPKFQSKQQPQDNFKNNVKKSQLPVQLD 451
Query: 447 LGDMLAALEKQQQAMKARQITNTRPLSYTVVTAASFHTKDSTNRKPLTKSQPCLTSFNSV 506
LG ML ALEK+Q + A+Q + +S V S + +++ + T N +
Sbjct: 452 LGGMLTALEKKQHSQHAKQSSKPVVVSVGAVPVLSKECASGERGRRMSQMK---TPHNPL 508
Query: 507 DIASSKAKKGKEKEIAKLKRPTALKKVILKEREEKKGRLTVD--HNLLGSEEPTEMHLDF 564
D ++ KKGK++EI K K+PT+LKK+ILKER+E+K RL + S++ +
Sbjct: 509 DSSAPLMKKGKQREIPKAKKPTSLKKIILKERQERKQRLQENAVSPAFTSDDTQDGESGG 568
Query: 565 IDDLPQEIVSQEDTGLS-MPSDTSLSPASQNSPYCMTPVSQGSPASSGIGSPMASSTITK 623
D P++ G+ + S S+ S+ P T + + + AS + +T K
Sbjct: 569 DDQFPEQAELSGPEGMDELISTPSVEDKSEEPPG--TELQRDTEASHLAPN---HTTFPK 623
Query: 624 IHSKRFREYCNQVLCKEIDECVTLLLQELVSFQERIYQKDPVRAKARRRLVMGLREVTKH 683
IHS+RFR+YC+Q+L KE+D CVT LL+ELV FQ+R+YQKDPV+AK +RRLV+GLREV KH
Sbjct: 624 IHSRRFRDYCSQMLSKEVDACVTDLLKELVRFQDRMYQKDPVKAKTKRRLVLGLREVLKH 683
Query: 684 MKLNKIKCVIISPNCEKIQSKGGLDEALYNVIAMAREQEIPFVFALGRKALGRCVNKLVP 743
+KL K+KCVIISPNCEKIQSKGGLD+ L+ +I A EQ IPFVFAL RKALGR +NK VP
Sbjct: 684 LKLKKLKCVIISPNCEKIQSKGGLDDTLHTIIDYACEQNIPFVFALNRKALGRSLNKAVP 743
Query: 744 VSVVGIFNYFGAESLFNKLVELTEEARKAYKDMVAAMEQEQAEEALKNVKKVPHHMGHSR 803
VSVVGIF+Y GA+ F+K+VELT AR+AYK M+ ++QE E
Sbjct: 744 VSVVGIFSYDGAQDQFHKMVELTVAARQAYKTMLENVQQELVGEPRPQAP---------- 793
Query: 804 NPSAASAISFCSVISEP--ISEVNEKEYETNWRNMVETSDGLEASENEKEVSCKHSTSE 860
PS + C P + E E Y W+ +E G E E S + STS+
Sbjct: 794 -PSLPTQGPSCPAEDGPPALKEKEEPHYIEIWKKHLEAYSGCTL---ELEESLEASTSQ 848
>gi|21735415 centromere protein B [Homo sapiens]
Length = 599
Score = 45.1 bits (105), Expect = 4e-04
Identities = 52/188 (27%), Positives = 77/188 (40%), Gaps = 35/188 (18%)
Query: 873 GKQPSLVATGSTTSATSAGKSTASDKEEVKPDDLEWASQQSTETGSLDGSCRDLLNSSIT 932
G+ PS G T A A+ + V+P D+ +++ G + T
Sbjct: 351 GQDPS----GLQLGLTEALHFVAAAWQAVEPSDIAACFREAGFGGG----------PNAT 396
Query: 933 STTSTLVPGMLEEEEDEDEEEEEDYTHEPISVEVQLNSRIESWVSETQRTMETLQLGKTL 992
TTS G EEEE+E+EEEEE E E E + E +LG+
Sbjct: 397 ITTSLKSEGEEEEEEEEEEEEEEGEGEE----------EEEEGEEEEEEGGEGEELGEEE 446
Query: 993 NGSEEDNVEQSGEEEAEAPEVLEPGMDSEAW------TADQQASPGQQKSSNCSSLN--- 1043
EE +V+ S EEE E E G+++E W + G Q+ + C +L+
Sbjct: 447 EVEEEGDVD-SDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLE 505
Query: 1044 -KEHSDSN 1050
E SDS+
Sbjct: 506 GGEDSDSD 513
>gi|38327039 heat shock 70kDa protein 4 [Homo sapiens]
Length = 840
Score = 44.7 bits (104), Expect = 5e-04
Identities = 46/197 (23%), Positives = 83/197 (42%), Gaps = 30/197 (15%)
Query: 815 SVISEPISEVNEKEYETNWRNMVETSDGLEASENEKEVSCKHSTSEKPSKLPFDTPPIGK 874
SV S + EV++ E E + +E +N KE E+ ++ + P + +
Sbjct: 491 SVSSASLVEVHKSE---------ENEEPMETDQNAKE--------EEKMQVDQEEPHVEE 533
Query: 875 QPSLVATGSTTSATSAGKSTASDKEEVKPDDLEWASQQSTETGSLDGSC---------RD 925
Q + + S A K++ K D A + +T ++D R+
Sbjct: 534 QQQQTPAENKAESEEMETSQAGSKDK-KMDQPPQAKKAKVKTSTVDLPIENQLLWQIDRE 592
Query: 926 LLNSSITSTTSTLVPGMLEEEEDEDEEEEEDYTHEPISVEVQLNSRIESWVSETQRTMET 985
+LN I + ++ LE+E ++ + E+Y +E + +L+ E +VSE R T
Sbjct: 593 MLNLYIENEGKMIMQDKLEKERNDAKNAVEEYVYE---MRDKLSGEYEKFVSEDDRNSFT 649
Query: 986 LQLGKTLNGSEEDNVEQ 1002
L+L T N ED +Q
Sbjct: 650 LKLEDTENWLYEDGEDQ 666
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 44.3 bits (103), Expect = 6e-04
Identities = 58/292 (19%), Positives = 103/292 (35%), Gaps = 31/292 (10%)
Query: 764 ELTEEARKAYKDMVAAMEQEQAEEALKNVKKVPHHMGHSRNPSAASAISFCSVISEPISE 823
E+TEE K K+ E+ EE + ++ +++P A A S P+ E
Sbjct: 469 EVTEEEEKEAKEEEGKEEEGGEEEEAEGGEE------ETKSPPAEEAASPEKEAKSPVKE 522
Query: 824 VNEKEYETNWRNMVETSDGLEASENEKEVSCKHSTSEKPSKLPFDTPPIGKQPSLVATGS 883
+ E E E EK ++ P+K +PP K P S
Sbjct: 523 EAKSPAEAKSPEKEEAKSPAEVKSPEK--------AKSPAKEEAKSPPEAKSPEKEEAKS 574
Query: 884 TTSATSAGKSTASDKEEVKPD----DLEWASQQSTETGSLDGSCRDLLNSSITSTTSTLV 939
S K+ + KEE K E A E + + S
Sbjct: 575 PAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKS 634
Query: 940 PGMLEE---------EEDEDEEEEEDYTHE----PISVEVQLNSRIESWVSETQRTMETL 986
P + E+ + E+EE + E P+ E + + +S V ++ E
Sbjct: 635 PEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKA 694
Query: 987 QLGKTLNGSEEDNVEQSGEEEAEAPEVLEPGMDSEAWTADQQASPGQQKSSN 1038
+ + + +EEA++PE + + EA T ++ SP ++++ +
Sbjct: 695 KSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKS 746
Score = 40.4 bits (93), Expect = 0.009
Identities = 54/301 (17%), Positives = 114/301 (37%), Gaps = 25/301 (8%)
Query: 755 AESLFNKLVELTEEARKAYKDMVAAMEQEQAEEALKNVK-KVPHHMGHSRNPSAASAISF 813
A+S + + E+A+ K+ + E+ ++ E K + K P ++ + + A F
Sbjct: 722 AKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKF 781
Query: 814 CSVISEPISEVNEKEYETNWRNMVETSDGLEASENE----KEVSCKHSTSEKPSKLPFDT 869
P+ E E ++ + + +A E E +EV EKP ++
Sbjct: 782 PEKAKSPVKE----EVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKE 837
Query: 870 PP-IGKQPSLVATGSTTSATSAGKSTASDKEEVKP--DDLEWASQQSTETGSLDGSCRDL 926
PP ++ AT T + K A KE KP ++ + + + + ++ +
Sbjct: 838 PPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEA 897
Query: 927 LNSSITSTTSTLVPGMLEEEEDEDEEEEEDYTHEPISVEVQLNSRIESWVSETQRTMETL 986
+ T P +E +ED +E+ EV ++ E + E
Sbjct: 898 EDKKKVPTPEKEAPAKVEVKEDAKPKEK---------TEVAKKEPDDAKAKEPSKPAEK- 947
Query: 987 QLGKTLNGSEEDNVEQSGEEEAEAPEVLEPGMDSEAWTADQQASPGQQKSSNCSSLNKEH 1046
K ++D E+ ++ E P+ + + + + + P +K+ SS +++
Sbjct: 948 ---KEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKD 1004
Query: 1047 S 1047
S
Sbjct: 1005 S 1005
>gi|52487176 tripartite motif-containing 37 protein [Homo sapiens]
Length = 964
Score = 43.5 bits (101), Expect = 0.001
Identities = 43/151 (28%), Positives = 69/151 (45%), Gaps = 8/151 (5%)
Query: 894 TASDKEEVKPDD-LEWASQQSTETGSLDGSCRDLLNSSITSTTSTLVPGMLEEEEDEDEE 952
T ++ PD+ L + + ET + +C D+L +T S V E+EEDE++
Sbjct: 447 TQKSRDLSPPDNHLSPQNDDALETRAKKSACSDMLLEGGPTTAS--VREAKEDEEDEEKI 504
Query: 953 EEEDYTHEPISVEVQLNSRIESWVSETQRTMETLQLGKTLNGSEEDNVEQ--SGEEEAEA 1010
+ EDY HE ++ L+ E V++ + + T N E D E+ SGE + E
Sbjct: 505 QNEDYHHELSDGDLDLDLVYEDEVNQLDGSSSSASSTATSNTEENDIDEETMSGENDVEY 564
Query: 1011 PEV-LEPG--MDSEAWTADQQASPGQQKSSN 1038
+ LE G M+ A +S G SS+
Sbjct: 565 NNMELEEGELMEDAAAAGPAGSSHGYVGSSS 595
>gi|15147333 tripartite motif-containing 37 protein [Homo sapiens]
Length = 964
Score = 43.5 bits (101), Expect = 0.001
Identities = 43/151 (28%), Positives = 69/151 (45%), Gaps = 8/151 (5%)
Query: 894 TASDKEEVKPDD-LEWASQQSTETGSLDGSCRDLLNSSITSTTSTLVPGMLEEEEDEDEE 952
T ++ PD+ L + + ET + +C D+L +T S V E+EEDE++
Sbjct: 447 TQKSRDLSPPDNHLSPQNDDALETRAKKSACSDMLLEGGPTTAS--VREAKEDEEDEEKI 504
Query: 953 EEEDYTHEPISVEVQLNSRIESWVSETQRTMETLQLGKTLNGSEEDNVEQ--SGEEEAEA 1010
+ EDY HE ++ L+ E V++ + + T N E D E+ SGE + E
Sbjct: 505 QNEDYHHELSDGDLDLDLVYEDEVNQLDGSSSSASSTATSNTEENDIDEETMSGENDVEY 564
Query: 1011 PEV-LEPG--MDSEAWTADQQASPGQQKSSN 1038
+ LE G M+ A +S G SS+
Sbjct: 565 NNMELEEGELMEDAAAAGPAGSSHGYVGSSS 595
>gi|157674363 protein phosphatase 1, regulatory subunit 15A [Homo
sapiens]
Length = 674
Score = 42.4 bits (98), Expect = 0.002
Identities = 72/304 (23%), Positives = 121/304 (39%), Gaps = 45/304 (14%)
Query: 772 AYKDMVAAMEQEQAEEALKNVKKVPHHMGHSRNPSAASAISFCSVISEPISEVNEKEYET 831
++++ A+E+E EEA VKK H ++ SA+S S S +S E+E +
Sbjct: 182 SHRECCPAVEEEDDEEA---VKKEAHR-------TSTSALSPGSKPSTWVSCPGEEENQA 231
Query: 832 NWRNMVETSDGLEASENEKEVSCKHSTSEKPSKLPFDTPPIGKQPSLVA---TGSTTSAT 888
E S G + VS + S S+ P + + ++ A TG +A
Sbjct: 232 TEDKRTERSKGARKTS----VSPRSSGSD-PRSWEYRSGEASEEKEEKAHKETGKGEAAP 286
Query: 889 SAGKSTASDKEEVK-----PDDLEWASQQSTETGSLDGS--CRDLLNSSITSTTSTLV-P 940
S + + ++K P D E ++ DG C + + + P
Sbjct: 287 GPQSSAPAQRPQLKSWWCQPSDEEEGEVKALGAAEKDGEAECPPCIPPPSAFLKAWVYWP 346
Query: 941 GM-LEEEEDEDEEEEEDYTHEPISVEVQLNSR-------IESWVSETQRTMETLQLGKTL 992
G EEEEDE+E+E+ D + E + +S ++SWV + E + +
Sbjct: 347 GEDTEEEEDEEEDEDSDSGSDEEEGEAEASSSTPATGVFLKSWVYQPGEDTEEEEDEDSD 406
Query: 993 NGSEEDNVEQSGEEEAEAPE--------VLEPGMDSEAWTADQQASPGQQKSSNCSSLNK 1044
GS ED E+ E A P V PG D+E D+ ++ + ++L +
Sbjct: 407 TGSAED--EREAETSASTPPASAFLKAWVYRPGEDTEE-EEDEDVDSEDKEDDSEAALGE 463
Query: 1045 EHSD 1048
SD
Sbjct: 464 AESD 467
>gi|95147342 chromodomain helicase DNA binding protein 9 [Homo
sapiens]
Length = 2881
Score = 41.6 bits (96), Expect = 0.004
Identities = 45/218 (20%), Positives = 86/218 (39%), Gaps = 21/218 (9%)
Query: 783 EQAEEALKNVKKVPHHMGHSRNPSAASAISFCSVISEPISEVNEKEYETNWRNMVETSDG 842
E+ + +N+K+ P S S +S + + SEP+S N ++ + G
Sbjct: 2043 EEMKVKSENLKEEPQS---SEEESMSSVETRTLIKSEPVSPKN---------GVLPQATG 2090
Query: 843 LEASENEKEVSCKHSTSEKPSKLPFDTPPIGKQPSLVATGSTTSATS---AGKSTASDKE 899
+ S + E + + P P K+P + GS +S+ S + +S+ S +
Sbjct: 2091 DQKSGGKCETDRRMVAARTE---PLTPNPASKKPRVHKRGSESSSDSDSDSERSSCSSRS 2147
Query: 900 EVKPDDLEWASQQSTETGSLDGSCRDLLNSSITSTTSTLVPGMLEEEEDEDEEEEEDYTH 959
+ +S + S SC +SS +ST+S+ EE + +EEE
Sbjct: 2148 SSSSSSSSCSHSRSGSSSSSSSSCSSASSSSSSSTSSSSSSSSSSSEESDSDEEEAQKRE 2207
Query: 960 EPISVEVQLNSRIESWVSETQRTMETLQLGKTLNGSEE 997
++ + S + T ++ Q+ NG+ E
Sbjct: 2208 STTHMKAYDEESVASLSTTQDETQDSFQMN---NGTPE 2242
Score = 30.8 bits (68), Expect = 7.0
Identities = 23/118 (19%), Positives = 48/118 (40%), Gaps = 13/118 (11%)
Query: 253 PTAESSSEQGASEADIDSDSGYCSPKHSNNQPAAGALRNPDSGTMNHVESSMCAGGVNWS 312
P + +S++D DS+ CS + S++ S + +H S G + S
Sbjct: 2121 PRVHKRGSESSSDSDSDSERSSCSSRSSSSS---------SSSSCSHSRS----GSSSSS 2167
Query: 313 NVTCQATQKKPWMEKNQTFSRGGRQTEQRNNSQDEDGFQELNENGNAKDENIQQKLSS 370
+ +C + + + S +E+ ++ ++E +E + A DE LS+
Sbjct: 2168 SSSCSSASSSSSSSTSSSSSSSSSSSEESDSDEEEAQKRESTTHMKAYDEESVASLST 2225
>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
Length = 727
Score = 41.6 bits (96), Expect = 0.004
Identities = 44/194 (22%), Positives = 79/194 (40%), Gaps = 19/194 (9%)
Query: 851 EVSCKHSTSEKPSKLPFDTPPIGKQPSLVATGSTTSATSAGKSTASDKEEVKPD--DLEW 908
EV + S S + SK ++ G TGS+ S+ G +T +++E V+ D + E
Sbjct: 158 EVDRRASRSSQSSKEEVNSEEYGSDHE---TGSSGSSDEQGNNTENEEEGVEEDVEEDEE 214
Query: 909 ASQQSTETGSLDGSCRDLLNSSITSTTSTLVPGMLEEEEDEDEEEEEDYTHEPISVEVQL 968
+ + E +D + EEEE+E+EEEEE+Y + + +
Sbjct: 215 VEEDAEEDEEVDEDGEEEEEEE-------------EEEEEEEEEEEEEYEQDERDQKEEG 261
Query: 969 NS-RIESWVSETQRTMETLQLGKTLNGSEEDNVEQSGEEEAEAPEVLEPGMDSEAWTADQ 1027
N S S++ + G +GS D ++ +E A + D +A +
Sbjct: 262 NDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKERKRARGISPIVFDRSGSSASE 321
Query: 1028 QASPGQQKSSNCSS 1041
+ ++K SS
Sbjct: 322 SYAGSEKKHEKLSS 335
Score = 30.4 bits (67), Expect = 9.2
Identities = 41/244 (16%), Positives = 88/244 (36%), Gaps = 25/244 (10%)
Query: 140 VNAITTECTERPSQLGQVFPLSSHRSRNSNRGSVVPKQQLLQQHIKSKRPLVKNVATQKE 199
+N + TE P Q +++ S + +N +GS ++ K ++P V + +
Sbjct: 13 LNVLDDILTEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSK 72
Query: 200 TNAAGPDSRSKIVLLVDAS----QQTDFPSDIANKSLSETTATMLWKSKGR--------- 246
++ + +IV S + ++ NK L L S R
Sbjct: 73 PLSSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEK 132
Query: 247 ---RRRASHPTAESSSEQGASEADIDSDSGYCSPKHSNNQPAAGALRNPDSGTMNHVESS 303
R+R A+S + G+ ++ D S+ + N + +H S
Sbjct: 133 TCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEV-----NSEEYGSDHETGS 187
Query: 304 MCAGGVNWSNVTCQATQKKPWMEKNQTFSRGGRQTEQRNNSQDEDGFQELNENGNAKDEN 363
+ +N + + +E+++ + E+ DEDG +E E ++E
Sbjct: 188 SGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEE----VDEDGEEEEEEEEEEEEEE 243
Query: 364 IQQK 367
+++
Sbjct: 244 EEEE 247
>gi|79750944 ubiquitin specific peptidase 42 [Homo sapiens]
Length = 1316
Score = 41.2 bits (95), Expect = 0.005
Identities = 48/196 (24%), Positives = 75/196 (38%), Gaps = 20/196 (10%)
Query: 854 CKHSTSEKPSKLPFDTPPIGKQPSLVATGSTTSATSAGKSTASDKEEVKPDDLEWASQQS 913
C+ + + L T P+ PS T S +TS + + + KP + Q
Sbjct: 535 CQSQPNLHSNSLENPTKPV---PSSTITNSAVQSTSNASTMSVSSKVTKPIPRSESCSQP 591
Query: 914 TETGSLDGSCRDLLNSSITSTTSTLVPGMLEEEEDEDEEEEEDYTHEPISVEVQLNSRIE 973
G + LNSS+ LVP E ED DEE + I V +S +
Sbjct: 592 VMNG------KSKLNSSV------LVPYGAESSEDSDEESKGLGKENGIGTIVSSHSPGQ 639
Query: 974 SWVSETQRTMETLQLGKTLNGSEEDNVEQSGEEEAEAPEVL----EPGMDSEAWTADQQA 1029
+ + T LQ TLNG+ + + +E AP+ +P + SE A
Sbjct: 640 D-AEDEEATPHELQEPMTLNGANSADSDSDPKENGLAPDGASCQGQPALHSENPFAKANG 698
Query: 1030 SPGQQKSSNCSSLNKE 1045
PG+ + SL ++
Sbjct: 699 LPGKLMPAPLLSLPED 714
>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
sapiens]
Length = 1130
Score = 40.0 bits (92), Expect = 0.012
Identities = 29/89 (32%), Positives = 41/89 (46%), Gaps = 3/89 (3%)
Query: 944 EEEEDEDEEEEEDYTHEPISVEVQLNSRIESWVSETQRTMETLQLGKTLNGSEEDNVEQS 1003
EEEE+E+EEEEE+ E E + E + E + E + + G E+ E+
Sbjct: 890 EEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEE 949
Query: 1004 GEEEAEAPEVLEPGMDSEAWTADQQASPG 1032
EEE E E +E D E TA + G
Sbjct: 950 DEEEEEELEEVE---DLEFGTAGGEVEEG 975
Score = 35.4 bits (80), Expect = 0.29
Identities = 39/175 (22%), Positives = 64/175 (36%), Gaps = 24/175 (13%)
Query: 858 TSEKPSKLPFDTPPIGKQPSLVATGSTTSATSAGKSTASDKEEVKPDDLEWASQQSTETG 917
T P +P TP G P+L + + S+ + ++EE + ++ E ++ E
Sbjct: 854 TLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEE 913
Query: 918 SLDGSCRDLLNSSITSTTSTLVPGMLEEEEDEDEEEEEDYTHEPISVEVQLNSRIESWVS 977
D EEEE+E+EE EE++ E +E + E
Sbjct: 914 EEDEE------------------EYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEE 955
Query: 978 ETQRTMETLQLGKTLNGSEEDNVEQSGEEEAEAPEVLEPGMDSEAWTADQQASPG 1032
E + +E L+ G T G VE+ P L P + + PG
Sbjct: 956 ELEE-VEDLEFG-TAGG----EVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPG 1004
>gi|33598960 alpha-2B-adrenergic receptor [Homo sapiens]
Length = 450
Score = 39.3 bits (90), Expect = 0.020
Identities = 37/123 (30%), Positives = 52/123 (42%), Gaps = 11/123 (8%)
Query: 874 KQPSLVATGSTTSATSAGKSTASDKEEVKPDDLEWASQQSTETGSLDGSCRDLLNSSITS 933
K P+L + S KST +E P+D T T +L S L NS
Sbjct: 233 KLPALASVASAREVNGHSKSTGEKEEGETPED--------TGTRALPPSWAALPNSGQGQ 284
Query: 934 TTSTLVPGMLEEEEDEDEEEEEDYTHEPISVEVQLNSRIESWVSETQ--RTMETLQLGKT 991
+E E+E+EEEEE+ EP +V V S + + Q R + TL+ G+
Sbjct: 285 KEGVCGASPEDEAEEEEEEEEEEEECEPQAVPVSPASACSPPLQQPQGSRVLATLR-GQV 343
Query: 992 LNG 994
L G
Sbjct: 344 LLG 346
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 39.3 bits (90), Expect = 0.020
Identities = 139/677 (20%), Positives = 239/677 (35%), Gaps = 97/677 (14%)
Query: 411 LATAQEYSEISMEQKKLQEALSKAAGKKNKTPVQLDLGDMLAALEKQQQAM--------- 461
L T+QE S E+K+ +E S A G +K ++L D L K+QQA
Sbjct: 830 LKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRD---RLPKKQQASASTDGVDKL 886
Query: 462 --KARQITNTRPLSYTVVTAASFHTKDSTNRKPLTKSQPCLTSF---NSVDIASSKAKKG 516
K + T+ S H K T +K F + D S KK
Sbjct: 887 SGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQ 946
Query: 517 KEKEIAKLKRPTALKKVILK----------------EREE----KKGRLTVDHNLLGSEE 556
+K + K+P+ KK ++K EREE KG + + E+
Sbjct: 947 SKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEK 1006
Query: 557 PTEMHLDFIDDLPQEI--VSQEDTGLSMPSDTSLSPASQNSPY----------------- 597
++ D E+ +++ TG D+S S+N Y
Sbjct: 1007 KSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKR 1066
Query: 598 ---CMTPVSQGSPASSGIGSPMASSTITKIHSKRFREYCNQVLCKEIDECVTLLLQELVS 654
+ + S G S + + +I + R ++ KEI + E S
Sbjct: 1067 QDCSSSDTEKYSMKEDGCNS--SDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESS 1124
Query: 655 ------FQERIYQKDPVRAKARRRLVMGLREVTKHMKLNKIKCVIISPNCEKIQSKGGLD 708
Q +K V K ++R + K + I + + +G D
Sbjct: 1125 EDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSD 1184
Query: 709 EALYNVIA--MAREQEIPFVFALGRKALGRCVNKLVPVSVVGIFNYFGAESLFNKLVELT 766
E + + F + G +AL +K VPV+V + E+ K + L
Sbjct: 1185 EQKIKPVTENLVLSSHTGFCQSSGDEAL----SKSVPVTVDDDDDDNDPENRIAKKM-LL 1239
Query: 767 EEARKAYKDMVAAMEQEQAEEALKNVKKVPHHMGHSRNPSAASAISFCSVISEPISEVNE 826
EE + ++ EE K K + NP A + + S+ SE ++
Sbjct: 1240 EEIKANLSSDEDGSSDDEPEEGKKRTGK-----QNEENPGDEEAKNQVNSESDSDSEESK 1294
Query: 827 KEYETN--WRNMVETSDGLEASENEKEVSCKHSTSEKPSKLPF---DTPPIGKQPSLVAT 881
K + R+ + SDG E+ E +K +H + ++ D+ Q S V+
Sbjct: 1295 KPRYRHRLLRHKLTVSDG-ESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSE 1353
Query: 882 GSTTSATSAGKSTASDKE-EVKPDDLEWASQQSTETGSL--DGSCRDLLNSSITSTTSTL 938
+ S T S K+ E++ + + ++ + D S + NS
Sbjct: 1354 EVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKE- 1412
Query: 939 VPGMLEEEEDEDEEEEEDYTHEPISVEVQLNSRIESWVSETQRTMETLQLGKTLNGSEED 998
EEEE+E+EEEEE+ ++ + +I + + + ET K EE+
Sbjct: 1413 ----EEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALK----EEEE 1464
Query: 999 NVEQSGEEEAEAPEVLE 1015
++ E E E ++ E
Sbjct: 1465 RRKRIAEREREREKLRE 1481
Score = 33.9 bits (76), Expect = 0.83
Identities = 30/127 (23%), Positives = 50/127 (39%), Gaps = 8/127 (6%)
Query: 929 SSITSTTSTLVPGMLEEEEDEDEEEEEDYTHEPISVEVQLNSRIESWVSETQRTMETLQL 988
SS S S + EE E E+E+ T E++ N R + +R +++
Sbjct: 1337 SSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRR----IKV 1392
Query: 989 GKTLNGSEEDNVEQSGEEEAEAPEVLEPGMDSEAWTADQQASPGQQKSSNCSSLNKEHSD 1048
+ + + N E+ EE+ E E E + E D SPG+ + + K D
Sbjct: 1393 QEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGR----KKIRKILKD 1448
Query: 1049 SNYTTQT 1055
T+T
Sbjct: 1449 DKLRTET 1455
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 39.3 bits (90), Expect = 0.020
Identities = 139/677 (20%), Positives = 239/677 (35%), Gaps = 97/677 (14%)
Query: 411 LATAQEYSEISMEQKKLQEALSKAAGKKNKTPVQLDLGDMLAALEKQQQAM--------- 461
L T+QE S E+K+ +E S A G +K ++L D L K+QQA
Sbjct: 868 LKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRD---RLPKKQQASASTDGVDKL 924
Query: 462 --KARQITNTRPLSYTVVTAASFHTKDSTNRKPLTKSQPCLTSF---NSVDIASSKAKKG 516
K + T+ S H K T +K F + D S KK
Sbjct: 925 SGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQ 984
Query: 517 KEKEIAKLKRPTALKKVILK----------------EREE----KKGRLTVDHNLLGSEE 556
+K + K+P+ KK ++K EREE KG + + E+
Sbjct: 985 SKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEK 1044
Query: 557 PTEMHLDFIDDLPQEI--VSQEDTGLSMPSDTSLSPASQNSPY----------------- 597
++ D E+ +++ TG D+S S+N Y
Sbjct: 1045 KSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKR 1104
Query: 598 ---CMTPVSQGSPASSGIGSPMASSTITKIHSKRFREYCNQVLCKEIDECVTLLLQELVS 654
+ + S G S + + +I + R ++ KEI + E S
Sbjct: 1105 QDCSSSDTEKYSMKEDGCNS--SDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESS 1162
Query: 655 ------FQERIYQKDPVRAKARRRLVMGLREVTKHMKLNKIKCVIISPNCEKIQSKGGLD 708
Q +K V K ++R + K + I + + +G D
Sbjct: 1163 EDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSD 1222
Query: 709 EALYNVIA--MAREQEIPFVFALGRKALGRCVNKLVPVSVVGIFNYFGAESLFNKLVELT 766
E + + F + G +AL +K VPV+V + E+ K + L
Sbjct: 1223 EQKIKPVTENLVLSSHTGFCQSSGDEAL----SKSVPVTVDDDDDDNDPENRIAKKM-LL 1277
Query: 767 EEARKAYKDMVAAMEQEQAEEALKNVKKVPHHMGHSRNPSAASAISFCSVISEPISEVNE 826
EE + ++ EE K K + NP A + + S+ SE ++
Sbjct: 1278 EEIKANLSSDEDGSSDDEPEEGKKRTGK-----QNEENPGDEEAKNQVNSESDSDSEESK 1332
Query: 827 KEYETN--WRNMVETSDGLEASENEKEVSCKHSTSEKPSKLPF---DTPPIGKQPSLVAT 881
K + R+ + SDG E+ E +K +H + ++ D+ Q S V+
Sbjct: 1333 KPRYRHRLLRHKLTVSDG-ESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSE 1391
Query: 882 GSTTSATSAGKSTASDKE-EVKPDDLEWASQQSTETGSL--DGSCRDLLNSSITSTTSTL 938
+ S T S K+ E++ + + ++ + D S + NS
Sbjct: 1392 EVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKE- 1450
Query: 939 VPGMLEEEEDEDEEEEEDYTHEPISVEVQLNSRIESWVSETQRTMETLQLGKTLNGSEED 998
EEEE+E+EEEEE+ ++ + +I + + + ET K EE+
Sbjct: 1451 ----EEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALK----EEEE 1502
Query: 999 NVEQSGEEEAEAPEVLE 1015
++ E E E ++ E
Sbjct: 1503 RRKRIAEREREREKLRE 1519
Score = 33.9 bits (76), Expect = 0.83
Identities = 30/127 (23%), Positives = 50/127 (39%), Gaps = 8/127 (6%)
Query: 929 SSITSTTSTLVPGMLEEEEDEDEEEEEDYTHEPISVEVQLNSRIESWVSETQRTMETLQL 988
SS S S + EE E E+E+ T E++ N R + +R +++
Sbjct: 1375 SSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRR----IKV 1430
Query: 989 GKTLNGSEEDNVEQSGEEEAEAPEVLEPGMDSEAWTADQQASPGQQKSSNCSSLNKEHSD 1048
+ + + N E+ EE+ E E E + E D SPG+ + + K D
Sbjct: 1431 QEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGR----KKIRKILKD 1486
Query: 1049 SNYTTQT 1055
T+T
Sbjct: 1487 DKLRTET 1493
>gi|38016156 hypothetical protein LOC55345 [Homo sapiens]
Length = 1062
Score = 38.9 bits (89), Expect = 0.026
Identities = 60/289 (20%), Positives = 122/289 (42%), Gaps = 38/289 (13%)
Query: 782 QEQAEEALKNVKKVPHHMGHSRNPSAASAISFCSVISEPISEVNEKEYETNWRNMVETSD 841
Q Q+E ++N + ++ +P +S + +P ++ ++ ++ +
Sbjct: 314 QHQSENTMRNKSRWAMYLSSQSSPIHSSTVDGNDTERKPKAQEDDVNSNLKDLSLQKIIQ 373
Query: 842 GLEA-SENEKEVSCKHSTSEK-PS---KLPFDTPPIGKQPSLVATGSTTSATSAGKSTAS 896
+E +E K+ + S PS ++ + P + SL T S SA + G + S
Sbjct: 374 FVETYAEERKKYNVDQSVGNNDPSWNQEVKLEIPSFNESSSLQVTCS--SAENDGILSES 431
Query: 897 DKEEVKPDDLEWASQQSTETGSLDGSCRDLLNSSITSTTSTLVPGMLEEEEDEDEEEEED 956
D +E D + Q+ + G + S N+ +T TL E+E ++ E +
Sbjct: 432 DIQE----DNKIPFNQN-DKGCIKESVLIKENAQEVNTCGTL-----EKEYEQSESSLPE 481
Query: 957 YTHEPISVEVQLNSRIES----WVSETQRTMETLQ-LGKTLNGSEEDNVE--------QS 1003
H + +E NSRI +SE++ E+L + ++L+ + +E ++
Sbjct: 482 LKH--LQIESSNNSRISDDITDMISESKMDNESLNSIHESLSNVTQPFLEVTFNLNNFET 539
Query: 1004 GEEEAEAPEVLEPGMDSEAWTADQQASPG------QQKSSNCSSLNKEH 1046
+ E E+ E + DSE+W D + G + +++NC + EH
Sbjct: 540 SDTEEESQESNKISQDSESWVKDILVNDGNSCFQKRSENTNCEEIEGEH 588
>gi|82830424 gon-4-like isoform a [Homo sapiens]
Length = 2240
Score = 38.5 bits (88), Expect = 0.034
Identities = 45/172 (26%), Positives = 72/172 (41%), Gaps = 25/172 (14%)
Query: 860 EKPSKLPFDTPPIGKQPSLVATGSTTSATSAGKSTASDKE-EVKPDDLEWASQQSTETGS 918
E+ P TP ++P T T + K+ S + EV+ L + ++ S
Sbjct: 1380 EEERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNALSSMDPEVR---LSSPPGKPEDSSS 1436
Query: 919 LDGSCRDLLNSSITSTTSTLVPGMLEEEEDEDEEEEEDYTHEPISVEVQLNSRIES---W 975
+DG S + + P E+ +EEEEED+ E +++S E
Sbjct: 1437 VDGQ----------SVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEEDEMSSASEESVLS 1486
Query: 976 VSETQRTMETL-------QLGKTLNGSEEDNVEQSGEEEAEAPEVLEPGMDS 1020
V E Q TME L ++ + EE++ E++ E E E E E GM+S
Sbjct: 1487 VPELQETMEKLTWLASERRMSQEGESEEENSQEENSEPEEEEEEEAE-GMES 1537
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 38.1 bits (87), Expect = 0.044
Identities = 33/114 (28%), Positives = 47/114 (41%), Gaps = 12/114 (10%)
Query: 902 KPDDLEWASQQSTETGSLDGSCRDLLNSSITSTTSTLVPGMLEEEEDEDEEEEEDYTHEP 961
KP E ++ + D S + SS S+++ G EEEE+E+EEEEE T E
Sbjct: 238 KPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSE- 296
Query: 962 ISVEVQLNSRIESWVSETQRTMETLQLGKTLNGSEEDNVEQSGEEEAEAPEVLE 1015
ES E + E + G + E + E+ EEE E E
Sbjct: 297 -----------ESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 339
Score = 30.8 bits (68), Expect = 7.0
Identities = 37/141 (26%), Positives = 52/141 (36%), Gaps = 27/141 (19%)
Query: 884 TTSATSAGKSTASDKEEVKPDDLEWASQQSTETGSLDGSCRDLLNSSITSTTSTLVPGML 943
T+SA S+ + S EE + ++ E + ST S +
Sbjct: 264 TSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE----------------------- 300
Query: 944 EEEEDEDEEEEEDYTHEPISVEVQLNSRIESWVSETQRTMETLQLGKTLNGSEEDNVEQS 1003
EEEE+E+EEEE E S + E + +R E L + + D S
Sbjct: 301 EEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRD----S 356
Query: 1004 GEEEAEAPEVLEPGMDSEAWT 1024
GE E EV E S A T
Sbjct: 357 GESEEAEEEVGEGTPQSSALT 377
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 38.1 bits (87), Expect = 0.044
Identities = 33/114 (28%), Positives = 47/114 (41%), Gaps = 12/114 (10%)
Query: 902 KPDDLEWASQQSTETGSLDGSCRDLLNSSITSTTSTLVPGMLEEEEDEDEEEEEDYTHEP 961
KP E ++ + D S + SS S+++ G EEEE+E+EEEEE T E
Sbjct: 248 KPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSE- 306
Query: 962 ISVEVQLNSRIESWVSETQRTMETLQLGKTLNGSEEDNVEQSGEEEAEAPEVLE 1015
ES E + E + G + E + E+ EEE E E
Sbjct: 307 -----------ESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 349
Score = 30.8 bits (68), Expect = 7.0
Identities = 37/141 (26%), Positives = 52/141 (36%), Gaps = 27/141 (19%)
Query: 884 TTSATSAGKSTASDKEEVKPDDLEWASQQSTETGSLDGSCRDLLNSSITSTTSTLVPGML 943
T+SA S+ + S EE + ++ E + ST S +
Sbjct: 274 TSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE----------------------- 310
Query: 944 EEEEDEDEEEEEDYTHEPISVEVQLNSRIESWVSETQRTMETLQLGKTLNGSEEDNVEQS 1003
EEEE+E+EEEE E S + E + +R E L + + D S
Sbjct: 311 EEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRD----S 366
Query: 1004 GEEEAEAPEVLEPGMDSEAWT 1024
GE E EV E S A T
Sbjct: 367 GESEEAEEEVGEGTPQSSALT 387
>gi|20336305 B-cell CLL/lymphoma 11A isoform 1 [Homo sapiens]
Length = 835
Score = 38.1 bits (87), Expect = 0.044
Identities = 33/120 (27%), Positives = 51/120 (42%), Gaps = 12/120 (10%)
Query: 901 VKPDD-LEWASQQSTETGSLDGSCRDLLNSSITSTTSTLVPGMLEEEEDEDEEEEEDYTH 959
VK DD L AS T L GS L S + S P ++ E DE+EEE+++
Sbjct: 436 VKSDDGLSTASSPEPGTSDLVGSASSALKSVVAKFKSENDPNLIPENGDEEEEEDDEEEE 495
Query: 960 EPISVEVQLNSRIESWVSETQRTME----TLQLGKTLNGSEEDNVEQSGEEEAEAPEVLE 1015
E E E ++E++R +L+ + S V G+E P+V++
Sbjct: 496 EEEEEE-------EEELTESERVDYGFGLSLEAARHHENSSRGAVVGVGDESRALPDVMQ 548
>gi|20336307 B-cell CLL/lymphoma 11A isoform 2 [Homo sapiens]
Length = 773
Score = 38.1 bits (87), Expect = 0.044
Identities = 33/120 (27%), Positives = 51/120 (42%), Gaps = 12/120 (10%)
Query: 901 VKPDD-LEWASQQSTETGSLDGSCRDLLNSSITSTTSTLVPGMLEEEEDEDEEEEEDYTH 959
VK DD L AS T L GS L S + S P ++ E DE+EEE+++
Sbjct: 436 VKSDDGLSTASSPEPGTSDLVGSASSALKSVVAKFKSENDPNLIPENGDEEEEEDDEEEE 495
Query: 960 EPISVEVQLNSRIESWVSETQRTME----TLQLGKTLNGSEEDNVEQSGEEEAEAPEVLE 1015
E E E ++E++R +L+ + S V G+E P+V++
Sbjct: 496 EEEEEE-------EEELTESERVDYGFGLSLEAARHHENSSRGAVVGVGDESRALPDVMQ 548
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform 9
[Homo sapiens]
Length = 771
Score = 38.1 bits (87), Expect = 0.044
Identities = 33/114 (28%), Positives = 47/114 (41%), Gaps = 12/114 (10%)
Query: 902 KPDDLEWASQQSTETGSLDGSCRDLLNSSITSTTSTLVPGMLEEEEDEDEEEEEDYTHEP 961
KP E ++ + D S + SS S+++ G EEEE+E+EEEEE T E
Sbjct: 239 KPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSE- 297
Query: 962 ISVEVQLNSRIESWVSETQRTMETLQLGKTLNGSEEDNVEQSGEEEAEAPEVLE 1015
ES E + E + G + E + E+ EEE E E
Sbjct: 298 -----------ESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 340
Score = 30.8 bits (68), Expect = 7.0
Identities = 37/141 (26%), Positives = 52/141 (36%), Gaps = 27/141 (19%)
Query: 884 TTSATSAGKSTASDKEEVKPDDLEWASQQSTETGSLDGSCRDLLNSSITSTTSTLVPGML 943
T+SA S+ + S EE + ++ E + ST S +
Sbjct: 265 TSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE----------------------- 301
Query: 944 EEEEDEDEEEEEDYTHEPISVEVQLNSRIESWVSETQRTMETLQLGKTLNGSEEDNVEQS 1003
EEEE+E+EEEE E S + E + +R E L + + D S
Sbjct: 302 EEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRD----S 357
Query: 1004 GEEEAEAPEVLEPGMDSEAWT 1024
GE E EV E S A T
Sbjct: 358 GESEEAEEEVGEGTPQSSALT 378
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform 8
[Homo sapiens]
Length = 780
Score = 38.1 bits (87), Expect = 0.044
Identities = 33/114 (28%), Positives = 47/114 (41%), Gaps = 12/114 (10%)
Query: 902 KPDDLEWASQQSTETGSLDGSCRDLLNSSITSTTSTLVPGMLEEEEDEDEEEEEDYTHEP 961
KP E ++ + D S + SS S+++ G EEEE+E+EEEEE T E
Sbjct: 248 KPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSE- 306
Query: 962 ISVEVQLNSRIESWVSETQRTMETLQLGKTLNGSEEDNVEQSGEEEAEAPEVLE 1015
ES E + E + G + E + E+ EEE E E
Sbjct: 307 -----------ESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 349
Score = 32.0 bits (71), Expect = 3.2
Identities = 63/280 (22%), Positives = 93/280 (33%), Gaps = 28/280 (10%)
Query: 764 ELTEEARKAYKDMVAAMEQEQAEEALKNVKKVPHHMGHSRNPSAASAISFCSVISEPISE 823
E E RK +++ EQ++A + K+ HSR + E +
Sbjct: 117 EREHERRKRHRE-----EQDKARREWERQKRREMAREHSRRERGNDGVCLFRDRLEQLER 171
Query: 824 VNEKE-----YETNWRNMVETSDGLEASENEKE----VSCKHST-----SEKPSKLPFDT 869
E+E + R E E E+E VS H T S+K +
Sbjct: 172 KRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSR 231
Query: 870 PPIGKQPSLVATGSTTSATSAGK----STASDKEEVKPDDLEWASQQSTETGSLDGSCRD 925
P G K SD +++ + + +S +S+ S GS +
Sbjct: 232 SPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEE 291
Query: 926 LLNSSITSTT-STLVPGMLEEEEDEDEEEEEDYTHEPISVEVQLNSRIESWVSETQRTME 984
ST EEEE+E+EEEE E S + E + +R E
Sbjct: 292 EEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENE 351
Query: 985 TLQLGKTLNGSEEDNVEQSGEEEAEAPEVLEPGMDSEAWT 1024
L + + D SGE E EV E S A T
Sbjct: 352 NHLLVVPESRFDRD----SGESEEAEEEVGEGTPQSSALT 387
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform 5
[Homo sapiens]
Length = 748
Score = 38.1 bits (87), Expect = 0.044
Identities = 33/114 (28%), Positives = 47/114 (41%), Gaps = 12/114 (10%)
Query: 902 KPDDLEWASQQSTETGSLDGSCRDLLNSSITSTTSTLVPGMLEEEEDEDEEEEEDYTHEP 961
KP E ++ + D S + SS S+++ G EEEE+E+EEEEE T E
Sbjct: 216 KPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSE- 274
Query: 962 ISVEVQLNSRIESWVSETQRTMETLQLGKTLNGSEEDNVEQSGEEEAEAPEVLE 1015
ES E + E + G + E + E+ EEE E E
Sbjct: 275 -----------ESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 317
Score = 30.8 bits (68), Expect = 7.0
Identities = 37/141 (26%), Positives = 52/141 (36%), Gaps = 27/141 (19%)
Query: 884 TTSATSAGKSTASDKEEVKPDDLEWASQQSTETGSLDGSCRDLLNSSITSTTSTLVPGML 943
T+SA S+ + S EE + ++ E + ST S +
Sbjct: 242 TSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE----------------------- 278
Query: 944 EEEEDEDEEEEEDYTHEPISVEVQLNSRIESWVSETQRTMETLQLGKTLNGSEEDNVEQS 1003
EEEE+E+EEEE E S + E + +R E L + + D S
Sbjct: 279 EEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRD----S 334
Query: 1004 GEEEAEAPEVLEPGMDSEAWT 1024
GE E EV E S A T
Sbjct: 335 GESEEAEEEVGEGTPQSSALT 355
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform 4
[Homo sapiens]
Length = 737
Score = 38.1 bits (87), Expect = 0.044
Identities = 33/114 (28%), Positives = 47/114 (41%), Gaps = 12/114 (10%)
Query: 902 KPDDLEWASQQSTETGSLDGSCRDLLNSSITSTTSTLVPGMLEEEEDEDEEEEEDYTHEP 961
KP E ++ + D S + SS S+++ G EEEE+E+EEEEE T E
Sbjct: 205 KPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSE- 263
Query: 962 ISVEVQLNSRIESWVSETQRTMETLQLGKTLNGSEEDNVEQSGEEEAEAPEVLE 1015
ES E + E + G + E + E+ EEE E E
Sbjct: 264 -----------ESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 306
Score = 30.8 bits (68), Expect = 7.0
Identities = 37/141 (26%), Positives = 52/141 (36%), Gaps = 27/141 (19%)
Query: 884 TTSATSAGKSTASDKEEVKPDDLEWASQQSTETGSLDGSCRDLLNSSITSTTSTLVPGML 943
T+SA S+ + S EE + ++ E + ST S +
Sbjct: 231 TSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE----------------------- 267
Query: 944 EEEEDEDEEEEEDYTHEPISVEVQLNSRIESWVSETQRTMETLQLGKTLNGSEEDNVEQS 1003
EEEE+E+EEEE E S + E + +R E L + + D S
Sbjct: 268 EEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRD----S 323
Query: 1004 GEEEAEAPEVLEPGMDSEAWT 1024
GE E EV E S A T
Sbjct: 324 GESEEAEEEVGEGTPQSSALT 344
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform 2
[Homo sapiens]
Length = 782
Score = 38.1 bits (87), Expect = 0.044
Identities = 33/114 (28%), Positives = 47/114 (41%), Gaps = 12/114 (10%)
Query: 902 KPDDLEWASQQSTETGSLDGSCRDLLNSSITSTTSTLVPGMLEEEEDEDEEEEEDYTHEP 961
KP E ++ + D S + SS S+++ G EEEE+E+EEEEE T E
Sbjct: 250 KPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSE- 308
Query: 962 ISVEVQLNSRIESWVSETQRTMETLQLGKTLNGSEEDNVEQSGEEEAEAPEVLE 1015
ES E + E + G + E + E+ EEE E E
Sbjct: 309 -----------ESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 351
Score = 30.8 bits (68), Expect = 7.0
Identities = 37/141 (26%), Positives = 52/141 (36%), Gaps = 27/141 (19%)
Query: 884 TTSATSAGKSTASDKEEVKPDDLEWASQQSTETGSLDGSCRDLLNSSITSTTSTLVPGML 943
T+SA S+ + S EE + ++ E + ST S +
Sbjct: 276 TSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE----------------------- 312
Query: 944 EEEEDEDEEEEEDYTHEPISVEVQLNSRIESWVSETQRTMETLQLGKTLNGSEEDNVEQS 1003
EEEE+E+EEEE E S + E + +R E L + + D S
Sbjct: 313 EEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRD----S 368
Query: 1004 GEEEAEAPEVLEPGMDSEAWT 1024
GE E EV E S A T
Sbjct: 369 GESEEAEEEVGEGTPQSSALT 389
>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
Length = 709
Score = 38.1 bits (87), Expect = 0.044
Identities = 59/294 (20%), Positives = 113/294 (38%), Gaps = 31/294 (10%)
Query: 762 LVELTEEARKAYKDMVAAMEQEQAEEALKNVKKVPHHMGHSRNPSAASAISFCSVISEPI 821
L E+ E+ + Y E EQ + K K+ M + ++ ++S+P+
Sbjct: 20 LTEVPEQDDELYNP-----ESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPL 74
Query: 822 SEV---NEKEYETNWRNMVE-TSDGLEASENEKEVSC--KHSTSEKPSKLPFDTPPIG-- 873
S N++ T ++ E ++ + SE K + K S S+ P+ P
Sbjct: 75 SSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTC 134
Query: 874 ---KQPSLVATGSTTSATS---------AGKSTASDKEEVKPDDLEWASQQSTETGSLDG 921
+ P A T + A +S+ S KEEV + E+ S ETGS
Sbjct: 135 VRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSE--EYGSDH--ETGSSGS 190
Query: 922 SCRDLLNSSITSTTSTLVPGMLEEEEDEDEEEEEDYTHEPISVEVQLNSRIESWVSETQR 981
S D ++ + + + E+EE E++ EE++ E E + E E +
Sbjct: 191 S--DEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEE 248
Query: 982 TMETLQLGKTLNGSEEDNVEQSGEEEAEAPEVLEPGMDSEAWTADQQASPGQQK 1035
E + + G++ D ++ + +E+ + + S + T ++K
Sbjct: 249 EYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKERK 302
Score = 37.7 bits (86), Expect = 0.058
Identities = 39/163 (23%), Positives = 68/163 (41%), Gaps = 19/163 (11%)
Query: 851 EVSCKHSTSEKPSKLPFDTPPIGKQPSLVATGSTTSATSAGKSTASDKEEVKPD--DLEW 908
EV + S S + SK ++ G TGS+ S+ G +T +++E V+ D + E
Sbjct: 158 EVDRRASRSSQSSKEEVNSEEYGSDHE---TGSSGSSDEQGNNTENEEEGVEEDVEEDEE 214
Query: 909 ASQQSTETGSLDGSCRDLLNSSITSTTSTLVPGMLEEEEDEDEEEEEDYTHEPISVEVQL 968
+ + E +D + EEEE+E+EEEEE+Y + + +
Sbjct: 215 VEEDAEEDEEVDEDGEEEEEEE-------------EEEEEEEEEEEEEYEQDERDQKEEG 261
Query: 969 NS-RIESWVSETQRTMETLQLGKTLNGSEEDNVEQSGEEEAEA 1010
N S S++ + G +GS D ++ +E A
Sbjct: 262 NDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKERKRA 304
Score = 30.4 bits (67), Expect = 9.2
Identities = 41/244 (16%), Positives = 88/244 (36%), Gaps = 25/244 (10%)
Query: 140 VNAITTECTERPSQLGQVFPLSSHRSRNSNRGSVVPKQQLLQQHIKSKRPLVKNVATQKE 199
+N + TE P Q +++ S + +N +GS ++ K ++P V + +
Sbjct: 13 LNVLDDILTEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSK 72
Query: 200 TNAAGPDSRSKIVLLVDAS----QQTDFPSDIANKSLSETTATMLWKSKGR--------- 246
++ + +IV S + ++ NK L L S R
Sbjct: 73 PLSSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEK 132
Query: 247 ---RRRASHPTAESSSEQGASEADIDSDSGYCSPKHSNNQPAAGALRNPDSGTMNHVESS 303
R+R A+S + G+ ++ D S+ + N + +H S
Sbjct: 133 TCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEV-----NSEEYGSDHETGS 187
Query: 304 MCAGGVNWSNVTCQATQKKPWMEKNQTFSRGGRQTEQRNNSQDEDGFQELNENGNAKDEN 363
+ +N + + +E+++ + E+ DEDG +E E ++E
Sbjct: 188 SGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEE----VDEDGEEEEEEEEEEEEEE 243
Query: 364 IQQK 367
+++
Sbjct: 244 EEEE 247
>gi|18093112 ABT1-associated protein [Homo sapiens]
Length = 851
Score = 38.1 bits (87), Expect = 0.044
Identities = 36/137 (26%), Positives = 60/137 (43%), Gaps = 16/137 (11%)
Query: 838 ETSDGLEASENEKEVSCKHSTS----EKPSKLPFDTPPIGKQPSLVATGSTTSATSA--- 890
++ + + ++ EK+ +H+T EK L T I K P + + + S
Sbjct: 157 DSKEFTQKNKKEKKNIVQHTTDSSLEEKQRTLDSGTSEIVKSPRIECSKTRREMQSVVQL 216
Query: 891 -------GKSTASDKEEVKPDDLEWASQQSTETGSLDGSCRDLLNSSITSTTSTLVPGML 943
G ++D E D LE S+ +E GS + S ++ +S+ +
Sbjct: 217 IMTRDSDGYENSTDGEMCDKDALEEDSESVSEIGSDEESENEI--TSVGRASGDDDGSED 274
Query: 944 EEEEDEDEEEEEDYTHE 960
+EEEDEDEEE+ED E
Sbjct: 275 DEEEDEDEEEDEDEDSE 291
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 37.7 bits (86), Expect = 0.058
Identities = 48/251 (19%), Positives = 100/251 (39%), Gaps = 29/251 (11%)
Query: 806 SAASAISFCSVISEPISEVNEKEYETNWRNMVETSDGLEASENEKEVSCKHSTSEKPSKL 865
S+ S+ S S S S ++ ++ N E+SD ++S+++ S S S
Sbjct: 668 SSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSS--- 724
Query: 866 PFDTPPIGKQPSLVATGSTTSATSAGKSTASDKEEVKPDDLEWASQQSTETGSLDGSCRD 925
D+ S ++ S+ S+ S+ S +SD + D +S S + S D S D
Sbjct: 725 --DSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSD--SSDSSNSSDSSDSSDSSDSS--D 778
Query: 926 LLNSSITSTTSTLVPGMLEEEEDEDEEEEEDYTHEPISVEVQLNSRIESWVSETQRTMET 985
NSS ++ +S + D D ++ S S++ + ++
Sbjct: 779 SSNSSDSNDSSN-------SSDSSDSSNSSDSSNSSDS-------------SDSSDSSDS 818
Query: 986 LQLGKTLNGSEEDNVEQSGEEEAEAPEVLEPGMDSEAWTADQQASPGQQKSSNCSSLNKE 1045
+ + + D+ + S ++ G DS++ ++ S+ SS + +
Sbjct: 819 DSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSD 878
Query: 1046 HSDSNYTTQTT 1056
SDS+ + +++
Sbjct: 879 SSDSSDSNESS 889
Score = 34.7 bits (78), Expect = 0.49
Identities = 28/165 (16%), Positives = 61/165 (36%)
Query: 216 DASQQTDFPSDIANKSLSETTATMLWKSKGRRRRASHPTAESSSEQGASEADIDSDSGYC 275
D+S +D + S+++ + R+ + SS+ S DS
Sbjct: 825 DSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSD 884
Query: 276 SPKHSNNQPAAGALRNPDSGTMNHVESSMCAGGVNWSNVTCQATQKKPWMEKNQTFSRGG 335
S + SN+ ++ + + DS + + SS + N S+ + + + + S
Sbjct: 885 SNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDS 944
Query: 336 RQTEQRNNSQDEDGFQELNENGNAKDENIQQKLSSKVLDDLPENS 380
+ +NS D + + + ++ D N S D ++S
Sbjct: 945 SDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSS 989
Score = 34.3 bits (77), Expect = 0.64
Identities = 39/234 (16%), Positives = 89/234 (38%), Gaps = 18/234 (7%)
Query: 818 SEPISEVNEKEYETNWRNMVETSDGLEASENEKEVSCKHSTSEKPSKLPFDTPPIGKQPS 877
SE S ++ + +++ N ++SD ++S++ + S+ S
Sbjct: 629 SESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDS-------------- 674
Query: 878 LVATGSTTSATSAGKSTASDKEEVKPDDLEWASQQSTETGSLDGSCRDLLNSSITSTTST 937
+ S++S+ S+ S +SD + S S+++ S D S NSS + ++++
Sbjct: 675 ---SDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNS 731
Query: 938 LVPGMLEEEEDEDEEEEEDYTHEPISVEVQLNSRIESWVSETQRTMETLQLGKTLNGS-E 996
D + + + + NS S S++ + ++ + + S
Sbjct: 732 SDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNS 791
Query: 997 EDNVEQSGEEEAEAPEVLEPGMDSEAWTADQQASPGQQKSSNCSSLNKEHSDSN 1050
D+ + S ++ DS + + S+ SS + + SDS+
Sbjct: 792 SDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSS 845
Score = 33.5 bits (75), Expect = 1.1
Identities = 25/146 (17%), Positives = 54/146 (36%)
Query: 218 SQQTDFPSDIANKSLSETTATMLWKSKGRRRRASHPTAESSSEQGASEADIDSDSGYCSP 277
S + SD +N S S ++ +S+ + S S + +D S
Sbjct: 794 SSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDS 853
Query: 278 KHSNNQPAAGALRNPDSGTMNHVESSMCAGGVNWSNVTCQATQKKPWMEKNQTFSRGGRQ 337
SN ++ + + DS ++ S + N S+ + ++ + + + S
Sbjct: 854 DSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSD 913
Query: 338 TEQRNNSQDEDGFQELNENGNAKDEN 363
+ +NS D ++N N+ D +
Sbjct: 914 SSDSSNSSDSSESSNSSDNSNSSDSS 939
Score = 33.5 bits (75), Expect = 1.1
Identities = 44/253 (17%), Positives = 103/253 (40%), Gaps = 9/253 (3%)
Query: 806 SAASAISFCSVISEPISEVNEKEYETNWRNMVETSDGLEASENEKEVSCKHSTSEKPSKL 865
S+ S+ S S S S+ NE ++ + +SD + + S S S S+
Sbjct: 867 SSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSES 926
Query: 866 PFDTPPIGKQPSLVATGSTTSATSAGKSTASDKEEVKPDDLEWASQQSTETGSLDGSCRD 925
+ S ++ S+ S+ S+ S +S+ + S S+++ S D S
Sbjct: 927 SNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSS------NSSDSSDSNSSDSSDSS 980
Query: 926 LLNSSITSTTSTLVPGMLEEEEDEDEEEEEDYTHEPISVEVQLNSRIESWVSETQRTMET 985
+ S S+ S+ + D + D + S + NS S S++ + ++
Sbjct: 981 NSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSD-SSNSSDSSNSSDSSDSSDS 1039
Query: 986 LQLGKTLNGSEEDNVEQSGE--EEAEAPEVLEPGMDSEAWTADQQASPGQQKSSNCSSLN 1043
+ + S+ + S + + +++ + + S++ + + + +S+ SS +
Sbjct: 1040 SDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDS 1099
Query: 1044 KEHSDSNYTTQTT 1056
+ SDS+ ++ ++
Sbjct: 1100 SDSSDSSDSSDSS 1112
Score = 33.1 bits (74), Expect = 1.4
Identities = 37/221 (16%), Positives = 84/221 (38%), Gaps = 6/221 (2%)
Query: 839 TSDGLEASENEKEVSCKHSTSEKPSKLPFDTPPIGKQPSLVATGSTTSATSAGK---STA 895
+SD ++S+++ S S S+ D+ S ++ S+ S+ S+ S +
Sbjct: 560 SSDSSDSSDSDSSDSNSSSDSDSSDS---DSSDSSDSDSSDSSNSSDSSDSSDSSDSSDS 616
Query: 896 SDKEEVKPDDLEWASQQSTETGSLDGSCRDLLNSSITSTTSTLVPGMLEEEEDEDEEEEE 955
SD + K D + S S D S + +SS S +S + + + +
Sbjct: 617 SDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSD 676
Query: 956 DYTHEPISVEVQLNSRIESWVSETQRTMETLQLGKTLNGSEEDNVEQSGEEEAEAPEVLE 1015
+ S + +S S + + S+ N S + + + + +
Sbjct: 677 SSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSD 736
Query: 1016 PGMDSEAWTADQQASPGQQKSSNCSSLNKEHSDSNYTTQTT 1056
S++ + ++ S+ SS + + SDS+ ++ ++
Sbjct: 737 SSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSS 777
Score = 32.3 bits (72), Expect = 2.4
Identities = 38/183 (20%), Positives = 77/183 (42%), Gaps = 12/183 (6%)
Query: 192 KNVATQKETNAAGPDSRSKIV--LLVDASQQTDFPSDIANKSLSETTATMLWKSKGRRRR 249
K+ +++ E++++ DS+S D+S +D SD +N S S ++ S
Sbjct: 623 KSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSD-SSDSSNSSNSSDSSDSSDSSDSSSSS 681
Query: 250 ASHPTAESS--------SEQGASEADIDSDSGYCSPKHSNNQPAAGALRNPDSG-TMNHV 300
S +++SS SE S DSDS S ++N + + + DS + N
Sbjct: 682 DSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSS 741
Query: 301 ESSMCAGGVNWSNVTCQATQKKPWMEKNQTFSRGGRQTEQRNNSQDEDGFQELNENGNAK 360
+SS + N S+ + + + + S + ++S D + +++ N+
Sbjct: 742 DSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSS 801
Query: 361 DEN 363
D +
Sbjct: 802 DSS 804
Score = 32.3 bits (72), Expect = 2.4
Identities = 36/177 (20%), Positives = 69/177 (38%), Gaps = 12/177 (6%)
Query: 216 DASQQTDFP--SDIANKSLSETTATMLWKSKGRRRRASHPTAESSSEQGASEADIDSDSG 273
D+S +D SD +N S S ++ S S +++SS+ ++++ SDS
Sbjct: 736 DSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSS 795
Query: 274 YCSPKH--SNNQPAAGALRNPDSGTMNHVESSMCAGGVNWSNVT--------CQATQKKP 323
S SN+ ++ + + DS + N +SS + + SN + +
Sbjct: 796 DSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDS 855
Query: 324 WMEKNQTFSRGGRQTEQRNNSQDEDGFQELNENGNAKDENIQQKLSSKVLDDLPENS 380
+ + S + +NS D + NE+ N+ D + S D +S
Sbjct: 856 SNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSS 912
Score = 31.2 bits (69), Expect = 5.4
Identities = 27/148 (18%), Positives = 61/148 (41%), Gaps = 1/148 (0%)
Query: 216 DASQQTDFPSDIANKSLSETTATMLWKSKGRRRRASHPTAESSSEQGASEADIDSDSGYC 275
D+S +D SD ++ S S ++ S S +++SS +S++ SDS
Sbjct: 999 DSSNSSD-SSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1057
Query: 276 SPKHSNNQPAAGALRNPDSGTMNHVESSMCAGGVNWSNVTCQATQKKPWMEKNQTFSRGG 335
S ++ + + + S + + ESS + N S+ + + + + S
Sbjct: 1058 SDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1117
Query: 336 RQTEQRNNSQDEDGFQELNENGNAKDEN 363
+ ++S D + +++ N+ D +
Sbjct: 1118 SDSSNSSDSSDSSDSSDSSDSSNSSDSS 1145
Score = 30.8 bits (68), Expect = 7.0
Identities = 31/177 (17%), Positives = 68/177 (38%), Gaps = 12/177 (6%)
Query: 880 ATGSTTSATSAGKSTASDKEEVKPDDLEWASQQSTETGSLDGSCRDLLNSSITSTTSTLV 939
+T T ++ S G + + K D + S S D D NSS +S +S
Sbjct: 517 STSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSS------DSDSSDSSNSSDSSDSSD-- 568
Query: 940 PGMLEEEEDEDEEEEEDYTHEPISVEVQLNSRIESWVSETQRTMETLQLGKTLNGSEEDN 999
+ D + + D + S +S S S++ + ++ + + S+ +
Sbjct: 569 ----SDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKS 624
Query: 1000 VEQSGEEEAEAPEVLEPGMDSEAWTADQQASPGQQKSSNCSSLNKEHSDSNYTTQTT 1056
E ++ + DS + + + +S+ SS + + SDS+ ++ ++
Sbjct: 625 DSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSS 681
Score = 30.8 bits (68), Expect = 7.0
Identities = 31/164 (18%), Positives = 64/164 (39%), Gaps = 4/164 (2%)
Query: 216 DASQQTDFPSDIANKSLSETTATMLWKSKGRRRRASHPTAESSSEQGASEADIDSDSGYC 275
D+S +D SD +N S S ++ S S ++ESS +S++ SDS
Sbjct: 1110 DSSDSSD-SSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDS 1168
Query: 276 SPKHSNNQPAAGALRNPDSGTMNHVESSMCAGGVNWSNVTCQATQKKPWMEKNQTFSRGG 335
S ++ + + + S + + +SS + + S+ + + + + S
Sbjct: 1169 SDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD---SSDSSDSSDS 1225
Query: 336 RQTEQRNNSQDEDGFQELNENGNAKDENIQQKLSSKVLDDLPEN 379
+ N S D + +++ N+ D + S D E+
Sbjct: 1226 SDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDES 1269
>gi|38788260 bromodomain PHD finger transcription factor isoform 2
[Homo sapiens]
Length = 2903
Score = 37.7 bits (86), Expect = 0.058
Identities = 55/245 (22%), Positives = 94/245 (38%), Gaps = 30/245 (12%)
Query: 162 SHRSRNSNRGSVVPKQQLLQQHIKSKRPLVKNVATQKETNAAGPDSRSKIVLLVDASQQT 221
++++R SN+ + + + + I++K+ + NV + +ET +T
Sbjct: 538 TNKARGSNKSFLAAANEEILESIRAKKGDIDNVKSPEETE--------------KDKNET 583
Query: 222 DFPSDIANKSLSETTATMLWKSKGRRRRASHPTAESSSEQGASEADID-SDSGYCSPKHS 280
+ S A K+ E ++ + + + T + EQG SE + D G +S
Sbjct: 584 ENDSKDAEKNREE------FEDQSLEKDSDDKTPDDDPEQGKSEEPTEVGDKG-----NS 632
Query: 281 NNQPAAGALRNPDSGTMNHVESSMCAGGVNWSNVTCQATQKKPWMEKNQTFSRGGRQT-E 339
+ N S + E G ++ + + +KK E Q +T E
Sbjct: 633 VSANLGDNTTNATSEETSPSEGRSPVGCLSETPDSSNMAEKKVASELPQDVPEEPNKTCE 692
Query: 340 QRNNSQDEDGFQELNENGNAKDE-NIQQKLSSKVLDDLPENSPINIVQTPIPITTSVPKR 398
N S Q EN N+ E N Q S+K DD PEN TP+ I +
Sbjct: 693 SSNTSATTTSIQPNLENSNSSSELNSSQSESAKAADD-PENGE-RESHTPVSIQEEIVGD 750
Query: 399 AKSQK 403
KS+K
Sbjct: 751 FKSEK 755
Score = 36.2 bits (82), Expect = 0.17
Identities = 53/253 (20%), Positives = 106/253 (41%), Gaps = 36/253 (14%)
Query: 764 ELTEEARKAYKDMVAAMEQEQAEEALKNVKKVPHHMGHSRNPSAASAISFCSVISEPISE 823
+LT +AR + K +AA EE L++++ + + ++P + +E
Sbjct: 536 DLTNKARGSNKSFLAAAN----EEILESIRAKKGDIDNVKSPEETEKDKNETENDSKDAE 591
Query: 824 VNEKEYETNWRNMVETSDGLEA--------SENEKEVSCK-------------HSTSEKP 862
N +E+E +++ + SD SE EV K ++TSE+
Sbjct: 592 KNREEFED--QSLEKDSDDKTPDDDPEQGKSEEPTEVGDKGNSVSANLGDNTTNATSEET 649
Query: 863 SKLPFDTPPIGKQPSLVATGSTTSATSAGKSTASDKEEVKPDDLEWASQQSTETGSLDGS 922
S P G+ P + + S+ A K AS+ + P++ + S + +
Sbjct: 650 S------PSEGRSPVGCLSETPDSSNMAEKKVASELPQDVPEEPNKTCESSNTSATTTSI 703
Query: 923 CRDLLNSSITSTTSTLVPGMLEEEEDEDEEEEEDYTHEPISVEVQLNSRIESWVSETQRT 982
+L NS+ +S ++ + +D + E E +H P+S++ ++ +S S + +
Sbjct: 704 QPNLENSNSSSELNSSQSESAKAADDPENGERE--SHTPVSIQEEIVGDFKSEKSNGELS 761
Query: 983 METLQLGKTLNGS 995
E+ GK +GS
Sbjct: 762 -ESPGAGKGASGS 773
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.124 0.346
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,364,088
Number of Sequences: 37866
Number of extensions: 2016253
Number of successful extensions: 15409
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 64
Number of HSP's successfully gapped in prelim test: 327
Number of HSP's that attempted gapping in prelim test: 12274
Number of HSP's gapped (non-prelim): 2128
length of query: 1056
length of database: 18,247,518
effective HSP length: 113
effective length of query: 943
effective length of database: 13,968,660
effective search space: 13172446380
effective search space used: 13172446380
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.