Guide to the Human Genome
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Search of human proteins with 59853099

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|59853099 dynamin 1 isoform 1 [Homo sapiens]
         (864 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|59853099 dynamin 1 isoform 1 [Homo sapiens]                       1725   0.0  
gi|56549117 dynamin 1 isoform 2 [Homo sapiens]                       1684   0.0  
gi|56549121 dynamin 2 isoform 1 [Homo sapiens]                       1373   0.0  
gi|56549123 dynamin 2 isoform 2 [Homo sapiens]                       1363   0.0  
gi|56549119 dynamin 2 isoform 3 [Homo sapiens]                       1363   0.0  
gi|42544243 dynamin 3 isoform a [Homo sapiens]                       1358   0.0  
gi|209915561 dynamin 3 isoform b [Homo sapiens]                      1355   0.0  
gi|56549125 dynamin 2 isoform 4 [Homo sapiens]                       1352   0.0  
gi|171460916 dynamin 1-like isoform 2 [Homo sapiens]                  459   e-129
gi|171460914 dynamin 1-like isoform 1 [Homo sapiens]                  459   e-129
gi|171460918 dynamin 1-like isoform 3 [Homo sapiens]                  459   e-129
gi|222136619 myxovirus resistance protein 1 [Homo sapiens]            238   2e-62
gi|222136617 myxovirus resistance protein 1 [Homo sapiens]            238   2e-62
gi|11342664 myxovirus resistance protein 2 [Homo sapiens]             215   2e-55
gi|239756350 PREDICTED: UPF0621 protein C-like [Homo sapiens]         162   1e-39
gi|239750876 PREDICTED: UPF0621 protein C-like [Homo sapiens]         162   1e-39
gi|169208224 PREDICTED: UPF0621 protein C-like [Homo sapiens]         162   1e-39
gi|113425405 PREDICTED: similar to dynamin 1 [Homo sapiens]           122   2e-27
gi|239745286 PREDICTED: hypothetical protein XP_002343417 [Homo ...   114   3e-25
gi|224831253 optic atrophy 1 isoform 8 [Homo sapiens]                 107   5e-23
gi|224831251 optic atrophy 1 isoform 7 [Homo sapiens]                 107   5e-23
gi|18860841 optic atrophy 1 isoform 6 [Homo sapiens]                  107   5e-23
gi|224831248 optic atrophy 1 isoform 5 [Homo sapiens]                 107   5e-23
gi|18860835 optic atrophy 1 isoform 4 [Homo sapiens]                  107   5e-23
gi|18860833 optic atrophy 1 isoform 3 [Homo sapiens]                  107   5e-23
gi|18860831 optic atrophy 1 isoform 2 [Homo sapiens]                  107   5e-23
gi|224831243 optic atrophy 1 isoform 1 [Homo sapiens]                 107   5e-23
gi|239745270 PREDICTED: hypothetical protein XP_002343416 [Homo ...   104   4e-22
gi|239745262 PREDICTED: hypothetical protein XP_002343372 [Homo ...   104   4e-22
gi|157168329 formin 1 [Homo sapiens]                                   61   5e-09

>gi|59853099 dynamin 1 isoform 1 [Homo sapiens]
          Length = 864

 Score = 1725 bits (4468), Expect = 0.0
 Identities = 864/864 (100%), Positives = 864/864 (100%)

Query: 1   MGNRGMEDLIPLVNRLQDAFSAIGQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
           MGNRGMEDLIPLVNRLQDAFSAIGQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG
Sbjct: 1   MGNRGMEDLIPLVNRLQDAFSAIGQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60

Query: 61  SGIVTRRPLVLQLVNATTEYAEFLHCKGKKFTDFEEVRLEIEAETDRVTGTNKGISPVPI 120
           SGIVTRRPLVLQLVNATTEYAEFLHCKGKKFTDFEEVRLEIEAETDRVTGTNKGISPVPI
Sbjct: 61  SGIVTRRPLVLQLVNATTEYAEFLHCKGKKFTDFEEVRLEIEAETDRVTGTNKGISPVPI 120

Query: 121 NLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANSD 180
           NLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANSD
Sbjct: 121 NLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANSD 180

Query: 181 LANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240
           LANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK
Sbjct: 181 LANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240

Query: 241 DIDGKKDITAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQLTNHIRDTLPGLRNKL 300
           DIDGKKDITAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQLTNHIRDTLPGLRNKL
Sbjct: 241 DIDGKKDITAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQLTNHIRDTLPGLRNKL 300

Query: 301 QSQLLSIEKEVEEYKNFRPDDPARKTKALLQMVQQFAVDFEKRIEGSGDQIDTYELSGGA 360
           QSQLLSIEKEVEEYKNFRPDDPARKTKALLQMVQQFAVDFEKRIEGSGDQIDTYELSGGA
Sbjct: 301 QSQLLSIEKEVEEYKNFRPDDPARKTKALLQMVQQFAVDFEKRIEGSGDQIDTYELSGGA 360

Query: 361 RINRIFHERFPFELVKMEFDEKELRREISYAIKNIHGIRTGLFTPDMAFETIVKKQVKKI 420
           RINRIFHERFPFELVKMEFDEKELRREISYAIKNIHGIRTGLFTPDMAFETIVKKQVKKI
Sbjct: 361 RINRIFHERFPFELVKMEFDEKELRREISYAIKNIHGIRTGLFTPDMAFETIVKKQVKKI 420

Query: 421 REPCLKCVDMVISELISTVRQCTKKLQQYPRLREEMERIVTTHIREREGRTKEQVMLLID 480
           REPCLKCVDMVISELISTVRQCTKKLQQYPRLREEMERIVTTHIREREGRTKEQVMLLID
Sbjct: 421 REPCLKCVDMVISELISTVRQCTKKLQQYPRLREEMERIVTTHIREREGRTKEQVMLLID 480

Query: 481 IELAYMNTNHEDFIGFANAQQRSNQMNKKKTSGNQDEILVIRKGWLTINNIGIMKGGSKE 540
           IELAYMNTNHEDFIGFANAQQRSNQMNKKKTSGNQDEILVIRKGWLTINNIGIMKGGSKE
Sbjct: 481 IELAYMNTNHEDFIGFANAQQRSNQMNKKKTSGNQDEILVIRKGWLTINNIGIMKGGSKE 540

Query: 541 YWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDY 600
           YWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDY
Sbjct: 541 YWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDY 600

Query: 601 RQLELACETQEEVDSWKASFLRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVE 660
           RQLELACETQEEVDSWKASFLRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVE
Sbjct: 601 RQLELACETQEEVDSWKASFLRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVE 660

Query: 661 TIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELLANLYSCGDQNTLMEESAE 720
           TIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELLANLYSCGDQNTLMEESAE
Sbjct: 661 TIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELLANLYSCGDQNTLMEESAE 720

Query: 721 QAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPT 780
           QAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPT
Sbjct: 721 QAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPT 780

Query: 781 PQRRAPAVPPARPGSRGPAPGPPPAGSALGGAPPVPSRPGASPDPFGPPPQVPSRPNRAP 840
           PQRRAPAVPPARPGSRGPAPGPPPAGSALGGAPPVPSRPGASPDPFGPPPQVPSRPNRAP
Sbjct: 781 PQRRAPAVPPARPGSRGPAPGPPPAGSALGGAPPVPSRPGASPDPFGPPPQVPSRPNRAP 840

Query: 841 PGVPSRSGQASPSRPESPRPPFDL 864
           PGVPSRSGQASPSRPESPRPPFDL
Sbjct: 841 PGVPSRSGQASPSRPESPRPPFDL 864


>gi|56549117 dynamin 1 isoform 2 [Homo sapiens]
          Length = 851

 Score = 1684 bits (4362), Expect = 0.0
 Identities = 844/844 (100%), Positives = 844/844 (100%)

Query: 1   MGNRGMEDLIPLVNRLQDAFSAIGQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
           MGNRGMEDLIPLVNRLQDAFSAIGQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG
Sbjct: 1   MGNRGMEDLIPLVNRLQDAFSAIGQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60

Query: 61  SGIVTRRPLVLQLVNATTEYAEFLHCKGKKFTDFEEVRLEIEAETDRVTGTNKGISPVPI 120
           SGIVTRRPLVLQLVNATTEYAEFLHCKGKKFTDFEEVRLEIEAETDRVTGTNKGISPVPI
Sbjct: 61  SGIVTRRPLVLQLVNATTEYAEFLHCKGKKFTDFEEVRLEIEAETDRVTGTNKGISPVPI 120

Query: 121 NLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANSD 180
           NLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANSD
Sbjct: 121 NLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANSD 180

Query: 181 LANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240
           LANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK
Sbjct: 181 LANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240

Query: 241 DIDGKKDITAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQLTNHIRDTLPGLRNKL 300
           DIDGKKDITAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQLTNHIRDTLPGLRNKL
Sbjct: 241 DIDGKKDITAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQLTNHIRDTLPGLRNKL 300

Query: 301 QSQLLSIEKEVEEYKNFRPDDPARKTKALLQMVQQFAVDFEKRIEGSGDQIDTYELSGGA 360
           QSQLLSIEKEVEEYKNFRPDDPARKTKALLQMVQQFAVDFEKRIEGSGDQIDTYELSGGA
Sbjct: 301 QSQLLSIEKEVEEYKNFRPDDPARKTKALLQMVQQFAVDFEKRIEGSGDQIDTYELSGGA 360

Query: 361 RINRIFHERFPFELVKMEFDEKELRREISYAIKNIHGIRTGLFTPDMAFETIVKKQVKKI 420
           RINRIFHERFPFELVKMEFDEKELRREISYAIKNIHGIRTGLFTPDMAFETIVKKQVKKI
Sbjct: 361 RINRIFHERFPFELVKMEFDEKELRREISYAIKNIHGIRTGLFTPDMAFETIVKKQVKKI 420

Query: 421 REPCLKCVDMVISELISTVRQCTKKLQQYPRLREEMERIVTTHIREREGRTKEQVMLLID 480
           REPCLKCVDMVISELISTVRQCTKKLQQYPRLREEMERIVTTHIREREGRTKEQVMLLID
Sbjct: 421 REPCLKCVDMVISELISTVRQCTKKLQQYPRLREEMERIVTTHIREREGRTKEQVMLLID 480

Query: 481 IELAYMNTNHEDFIGFANAQQRSNQMNKKKTSGNQDEILVIRKGWLTINNIGIMKGGSKE 540
           IELAYMNTNHEDFIGFANAQQRSNQMNKKKTSGNQDEILVIRKGWLTINNIGIMKGGSKE
Sbjct: 481 IELAYMNTNHEDFIGFANAQQRSNQMNKKKTSGNQDEILVIRKGWLTINNIGIMKGGSKE 540

Query: 541 YWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDY 600
           YWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDY
Sbjct: 541 YWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDY 600

Query: 601 RQLELACETQEEVDSWKASFLRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVE 660
           RQLELACETQEEVDSWKASFLRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVE
Sbjct: 601 RQLELACETQEEVDSWKASFLRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVE 660

Query: 661 TIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELLANLYSCGDQNTLMEESAE 720
           TIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELLANLYSCGDQNTLMEESAE
Sbjct: 661 TIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELLANLYSCGDQNTLMEESAE 720

Query: 721 QAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPT 780
           QAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPT
Sbjct: 721 QAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPT 780

Query: 781 PQRRAPAVPPARPGSRGPAPGPPPAGSALGGAPPVPSRPGASPDPFGPPPQVPSRPNRAP 840
           PQRRAPAVPPARPGSRGPAPGPPPAGSALGGAPPVPSRPGASPDPFGPPPQVPSRPNRAP
Sbjct: 781 PQRRAPAVPPARPGSRGPAPGPPPAGSALGGAPPVPSRPGASPDPFGPPPQVPSRPNRAP 840

Query: 841 PGVP 844
           PGVP
Sbjct: 841 PGVP 844


>gi|56549121 dynamin 2 isoform 1 [Homo sapiens]
          Length = 870

 Score = 1373 bits (3554), Expect = 0.0
 Identities = 693/877 (79%), Positives = 774/877 (88%), Gaps = 31/877 (3%)

Query: 1   MGNRGMEDLIPLVNRLQDAFSAIGQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
           MGNRGME+LIPLVN+LQDAFS+IGQ+  LDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG
Sbjct: 1   MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60

Query: 61  SGIVTRRPLVLQLVNATTEYAEFLHCKGKKFTDFEEVRLEIEAETDRVTGTNKGISPVPI 120
           SGIVTRRPL+LQL+ + TE+AEFLHCK KKFTDF+EVR EIEAETDRVTGTNKGISPVPI
Sbjct: 61  SGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPI 120

Query: 121 NLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANSD 180
           NLRVYSPHVLNLTL+DLPG+TKVPVGDQPPDIE+QI+DM++QF+++E+ LILAV+PAN D
Sbjct: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD 180

Query: 181 LANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240
           LANSDALK+AKEVDPQG RTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK
Sbjct: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240

Query: 241 DIDGKKDITAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQLTNHIRDTLPGLRNKL 300
           DI+GKKDI AALAAERKFFLSHP+YRH+ADRMGTP+LQK LNQQLTNHIR++LP LR+KL
Sbjct: 241 DIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKL 300

Query: 301 QSQLLSIEKEVEEYKNFRPDDPARKTKALLQMVQQFAVDFEKRIEGSGDQIDTYELSGGA 360
           QSQLLS+EKEVEEYKNFRPDDP RKTKALLQMVQQF VDFEKRIEGSGDQ+DT ELSGGA
Sbjct: 301 QSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGA 360

Query: 361 RINRIFHERFPFELVKMEFDEKELRREISYAIKNIHGIRTGLFTPDMAFETIVKKQVKKI 420
           RINRIFHERFPFELVKMEFDEK+LRREISYAIKNIHG+RTGLFTPD+AFE IVKKQV K+
Sbjct: 361 RINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKL 420

Query: 421 REPCLKCVDMVISELISTVRQCTKKLQQYPRLREEMERIVTTHIREREGRTKEQVMLLID 480
           +EPCLKCVD+VI ELI+TVRQCT KL  YPRLREE ERIVTT+IREREGRTK+Q++LLID
Sbjct: 421 KEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLID 480

Query: 481 IELAYMNTNHEDFIGFANAQQRSNQMNKKKTSGNQDEILVIRKGWLTINNIGIMKGGSKE 540
           IE +Y+NTNHEDFIGFANAQQRS Q+NKK+   NQ EILVIR+GWLTINNI +MKGGSKE
Sbjct: 481 IEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKE 540

Query: 541 YWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDY 600
           YWFVLTAE+LSWYKD+EEKEKKYML +DNLK+RDVEKGFMS+KH+FA+FNTEQRNVYKD 
Sbjct: 541 YWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDL 600

Query: 601 RQLELACETQEEVDSWKASFLRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVE 660
           RQ+ELAC++QE+VDSWKASFLRAGVYP      EK     E+G+     SMDPQLERQVE
Sbjct: 601 RQIELACDSQEDVDSWKASFLRAGVYP------EKDQAENEDGAQENTFSMDPQLERQVE 654

Query: 661 TIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELLANLYSCGDQNTLMEESAE 720
           TIRNLVDSY+AI+NK++RDLMPKTIMHLMINNTK FI  ELLA LYS  DQ++LMEESA+
Sbjct: 655 TIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESAD 714

Query: 721 QAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPT 780
           QAQRRD+MLRMYHALKEAL+IIGDI+T+TVSTP+PPPVDD+WLQ  S        + SPT
Sbjct: 715 QAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSAS--------SHSPT 766

Query: 781 PQRR--APAVPPARPGS-RGPAPGPP----PAGSALG-GAPPVPSRPG-----ASPDPFG 827
           PQRR  +   PP RP + RGP PGPP    P G+A    APP+PSRPG     A+ D F 
Sbjct: 767 PQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFP 826

Query: 828 PPPQVPSRPNR----APPGVPSRSGQASPSRPESPRP 860
            PPQ+PSRP R     PPGVPSR   A+PSRP   RP
Sbjct: 827 APPQIPSRPVRIPPGIPPGVPSRRPPAAPSRPTIIRP 863


>gi|56549123 dynamin 2 isoform 2 [Homo sapiens]
          Length = 870

 Score = 1363 bits (3527), Expect = 0.0
 Identities = 686/877 (78%), Positives = 772/877 (88%), Gaps = 31/877 (3%)

Query: 1   MGNRGMEDLIPLVNRLQDAFSAIGQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
           MGNRGME+LIPLVN+LQDAFS+IGQ+  LDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG
Sbjct: 1   MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60

Query: 61  SGIVTRRPLVLQLVNATTEYAEFLHCKGKKFTDFEEVRLEIEAETDRVTGTNKGISPVPI 120
           SGIVTRRPL+LQL+ + TE+AEFLHCK KKFTDF+EVR EIEAETDRVTGTNKGISPVPI
Sbjct: 61  SGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPI 120

Query: 121 NLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANSD 180
           NLRVYSPHVLNLTL+DLPG+TKVPVGDQPPDIE+QI+DM++QF+++E+ LILAV+PAN D
Sbjct: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD 180

Query: 181 LANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240
           LANSDALK+AKEVDPQG RTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK
Sbjct: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240

Query: 241 DIDGKKDITAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQLTNHIRDTLPGLRNKL 300
           DI+GKKDI AALAAERKFFLSHP+YRH+ADRMGTP+LQK LNQQLTNHIR++LP LR+KL
Sbjct: 241 DIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKL 300

Query: 301 QSQLLSIEKEVEEYKNFRPDDPARKTKALLQMVQQFAVDFEKRIEGSGDQIDTYELSGGA 360
           QSQLLS+EKEVEEYKNFRPDDP RKTKALLQMVQQF VDFEKRIEGSGDQ+DT ELSGGA
Sbjct: 301 QSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGA 360

Query: 361 RINRIFHERFPFELVKMEFDEKELRREISYAIKNIHGIRTGLFTPDMAFETIVKKQVKKI 420
           RINRIFHERFPFELVKMEFDEK+LRREISYAIKNIHG+RTGLFTPDMAFE IVKKQ+ K+
Sbjct: 361 RINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAFEAIVKKQIVKL 420

Query: 421 REPCLKCVDMVISELISTVRQCTKKLQQYPRLREEMERIVTTHIREREGRTKEQVMLLID 480
           +EP LKCVD+V+SEL + +++C +KL  YPRLREE ERIVTT+IREREGRTK+Q++LLID
Sbjct: 421 KEPSLKCVDLVVSELATVIKKCAEKLSSYPRLREETERIVTTYIREREGRTKDQILLLID 480

Query: 481 IELAYMNTNHEDFIGFANAQQRSNQMNKKKTSGNQDEILVIRKGWLTINNIGIMKGGSKE 540
           IE +Y+NTNHEDFIGFANAQQRS Q+NKK+   NQ EILVIR+GWLTINNI +MKGGSKE
Sbjct: 481 IEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKE 540

Query: 541 YWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDY 600
           YWFVLTAE+LSWYKD+EEKEKKYML +DNLK+RDVEKGFMS+KH+FA+FNTEQRNVYKD 
Sbjct: 541 YWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDL 600

Query: 601 RQLELACETQEEVDSWKASFLRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVE 660
           RQ+ELAC++QE+VDSWKASFLRAGVYP      EK     E+G+     SMDPQLERQVE
Sbjct: 601 RQIELACDSQEDVDSWKASFLRAGVYP------EKDQAENEDGAQENTFSMDPQLERQVE 654

Query: 661 TIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELLANLYSCGDQNTLMEESAE 720
           TIRNLVDSY+AI+NK++RDLMPKTIMHLMINNTK FI  ELLA LYS  DQ++LMEESA+
Sbjct: 655 TIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESAD 714

Query: 721 QAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPT 780
           QAQRRD+MLRMYHALKEAL+IIGDI+T+TVSTP+PPPVDD+WLQ  S        + SPT
Sbjct: 715 QAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSAS--------SHSPT 766

Query: 781 PQRR--APAVPPARPGS-RGPAPGPP----PAGSALG-GAPPVPSRPG-----ASPDPFG 827
           PQRR  +   PP RP + RGP PGPP    P G+A    APP+PSRPG     A+ D F 
Sbjct: 767 PQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFP 826

Query: 828 PPPQVPSRPNR----APPGVPSRSGQASPSRPESPRP 860
            PPQ+PSRP R     PPGVPSR   A+PSRP   RP
Sbjct: 827 APPQIPSRPVRIPPGIPPGVPSRRPPAAPSRPTIIRP 863


>gi|56549119 dynamin 2 isoform 3 [Homo sapiens]
          Length = 866

 Score = 1363 bits (3527), Expect = 0.0
 Identities = 690/877 (78%), Positives = 771/877 (87%), Gaps = 35/877 (3%)

Query: 1   MGNRGMEDLIPLVNRLQDAFSAIGQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
           MGNRGME+LIPLVN+LQDAFS+IGQ+  LDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG
Sbjct: 1   MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60

Query: 61  SGIVTRRPLVLQLVNATTEYAEFLHCKGKKFTDFEEVRLEIEAETDRVTGTNKGISPVPI 120
           SGIVTRRPL+LQL+ + TE+AEFLHCK KKFTDF+EVR EIEAETDRVTGTNKGISPVPI
Sbjct: 61  SGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPI 120

Query: 121 NLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANSD 180
           NLRVYSPHVLNLTL+DLPG+TKVPVGDQPPDIE+QI+DM++QF+++E+ LILAV+PAN D
Sbjct: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD 180

Query: 181 LANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240
           LANSDALK+AKEVDPQG RTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK
Sbjct: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240

Query: 241 DIDGKKDITAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQLTNHIRDTLPGLRNKL 300
           DI+GKKDI AALAAERKFFLSHP+YRH+ADRMGTP+LQK LNQQLTNHIR++LP LR+KL
Sbjct: 241 DIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKL 300

Query: 301 QSQLLSIEKEVEEYKNFRPDDPARKTKALLQMVQQFAVDFEKRIEGSGDQIDTYELSGGA 360
           QSQLLS+EKEVEEYKNFRPDDP RKTKALLQMVQQF VDFEKRIEGSGDQ+DT ELSGGA
Sbjct: 301 QSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGA 360

Query: 361 RINRIFHERFPFELVKMEFDEKELRREISYAIKNIHGIRTGLFTPDMAFETIVKKQVKKI 420
           RINRIFHERFPFELVKMEFDEK+LRREISYAIKNIHG+RTGLFTPD+AFE IVKKQV K+
Sbjct: 361 RINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKL 420

Query: 421 REPCLKCVDMVISELISTVRQCTKKLQQYPRLREEMERIVTTHIREREGRTKEQVMLLID 480
           +EPCLKCVD+VI ELI+TVRQCT KL  YPRLREE ERIVTT+IREREGRTK+Q++LLID
Sbjct: 421 KEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLID 480

Query: 481 IELAYMNTNHEDFIGFANAQQRSNQMNKKKTSGNQDEILVIRKGWLTINNIGIMKGGSKE 540
           IE +Y+NTNHEDFIGFANAQQRS Q+NKK+   NQ    VIR+GWLTINNI +MKGGSKE
Sbjct: 481 IEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQ----VIRRGWLTINNISLMKGGSKE 536

Query: 541 YWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDY 600
           YWFVLTAE+LSWYKD+EEKEKKYML +DNLK+RDVEKGFMS+KH+FA+FNTEQRNVYKD 
Sbjct: 537 YWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDL 596

Query: 601 RQLELACETQEEVDSWKASFLRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVE 660
           RQ+ELAC++QE+VDSWKASFLRAGVYP      EK     E+G+     SMDPQLERQVE
Sbjct: 597 RQIELACDSQEDVDSWKASFLRAGVYP------EKDQAENEDGAQENTFSMDPQLERQVE 650

Query: 661 TIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELLANLYSCGDQNTLMEESAE 720
           TIRNLVDSY+AI+NK++RDLMPKTIMHLMINNTK FI  ELLA LYS  DQ++LMEESA+
Sbjct: 651 TIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESAD 710

Query: 721 QAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPT 780
           QAQRRD+MLRMYHALKEAL+IIGDI+T+TVSTP+PPPVDD+WLQ  S        + SPT
Sbjct: 711 QAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSAS--------SHSPT 762

Query: 781 PQRR--APAVPPARPGS-RGPAPGPP----PAGSALG-GAPPVPSRPG-----ASPDPFG 827
           PQRR  +   PP RP + RGP PGPP    P G+A    APP+PSRPG     A+ D F 
Sbjct: 763 PQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFP 822

Query: 828 PPPQVPSRPNR----APPGVPSRSGQASPSRPESPRP 860
            PPQ+PSRP R     PPGVPSR   A+PSRP   RP
Sbjct: 823 APPQIPSRPVRIPPGIPPGVPSRRPPAAPSRPTIIRP 859


>gi|42544243 dynamin 3 isoform a [Homo sapiens]
          Length = 863

 Score = 1358 bits (3515), Expect = 0.0
 Identities = 692/868 (79%), Positives = 760/868 (87%), Gaps = 20/868 (2%)

Query: 1   MGNRGMEDLIPLVNRLQDAFSAIGQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
           MGNR ME+LIPLVNRLQDAFSA+GQ+  L+LPQIAVVGGQSAGKSSVLENFVGRDFLPRG
Sbjct: 1   MGNREMEELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60

Query: 61  SGIVTRRPLVLQLVNATTEYAEFLHCKGKKFTDFEEVRLEIEAETDRVTGTNKGISPVPI 120
           SGIVTRRPLVLQLV +  EYAEFLHCKGKKFTDF+EVRLEIEAETDRVTG NKGIS +PI
Sbjct: 61  SGIVTRRPLVLQLVTSKAEYAEFLHCKGKKFTDFDEVRLEIEAETDRVTGMNKGISSIPI 120

Query: 121 NLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANSD 180
           NLRVYSPHVLNLTL+DLPG+TKVPVGDQPPDIE+QIR+M+MQF+T+ENCLILAV+PAN+D
Sbjct: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANTD 180

Query: 181 LANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240
           LANSDALK+AKEVDPQG RTIGVITKLDLMDEGTDARDVLENKLLPLRRGY+GVVNRSQK
Sbjct: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYVGVVNRSQK 240

Query: 241 DIDGKKDITAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQLTNHIRDTLPGLRNKL 300
           DIDGKKDI AA+ AERKFFLSHP+YRH+ADRMGTP+LQKVLNQQLTNHIRDTLP  RNKL
Sbjct: 241 DIDGKKDIKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQLTNHIRDTLPNFRNKL 300

Query: 301 QSQLLSIEKEVEEYKNFRPDDPARKTKALLQMVQQFAVDFEKRIEGSGDQIDTYELSGGA 360
           Q QLLSIE EVE YKNF+P+DP RKTKALLQMVQQFAVDFEKRIEGSGDQ+DT ELSGGA
Sbjct: 301 QGQLLSIEHEVEAYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGDQVDTLELSGGA 360

Query: 361 RINRIFHERFPFELVKMEFDEKELRREISYAIKNIHGIRTGLFTPDMAFETIVKKQVKKI 420
           +INRIFHERFPFE+VKMEF+EKELRREISYAIKNIHGIRTGLFTPDMAFE IVKKQ+ K+
Sbjct: 361 KINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAFEAIVKKQIVKL 420

Query: 421 REPCLKCVDMVISELISTVRQCTKKLQQYPRLREEMERIVTTHIREREGRTKEQVMLLID 480
           + P LK VD+VI ELI+TV++CTKKL  +PRL EE ERIV  HIREREG+TK+QV+LLID
Sbjct: 421 KGPSLKSVDLVIQELINTVKKCTKKLANFPRLCEETERIVANHIREREGKTKDQVLLLID 480

Query: 481 IELAYMNTNHEDFIGFANAQQRSNQMNKKKTSGNQDEILVIRKGWLTINNIGIMKGGSKE 540
           I+++Y+NTNHEDFIGFANAQQRS+Q++KK T GNQ    VIRKGWLTI+NIGIMKGGSK 
Sbjct: 481 IQVSYINTNHEDFIGFANAQQRSSQVHKKTTVGNQ----VIRKGWLTISNIGIMKGGSKG 536

Query: 541 YWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDY 600
           YWFVLTAE+LSWYKDDEEKEKKYML +DNLK+RDVEK FMSSKHIFALFNTEQRNVYKDY
Sbjct: 537 YWFVLTAESLSWYKDDEEKEKKYMLPLDNLKVRDVEKSFMSSKHIFALFNTEQRNVYKDY 596

Query: 601 RQLELACETQEEVDSWKASFLRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVE 660
           R LELAC++QE+VDSWKAS LRAGVYP++     KA   E   +++F  SMDPQLERQVE
Sbjct: 597 RFLELACDSQEDVDSWKASLLRAGVYPDKSVGNNKAENDENGQAENF--SMDPQLERQVE 654

Query: 661 TIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELLANLYSCGDQNTLMEESAE 720
           TIRNLVDSYM+I+NK +RDL+PKTIMHLMINN K+FI SELLA LYS  DQNTLMEESAE
Sbjct: 655 TIRNLVDSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLMEESAE 714

Query: 721 QAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPT 780
           QAQRRDEMLRMY ALKEAL IIGDI+T TVSTP PPPVDDSW+Q       RRSP  SPT
Sbjct: 715 QAQRRDEMLRMYQALKEALGIIGDISTATVSTPAPPPVDDSWIQ-----HSRRSPPPSPT 769

Query: 781 PQRRAP-AVPPARPGS-RGPAPGPPPAGSALGGAPPVPSRPG------ASPDPFGPPPQV 832
            QRR   + P ARP S RGPAP  P  G    GAPPVP RPG      +S D FG PPQV
Sbjct: 770 TQRRPTLSAPLARPTSGRGPAPAIPSPGPH-SGAPPVPFRPGPLPPFPSSSDSFGAPPQV 828

Query: 833 PSRPNRAPPGVPSRSGQASPSRPESPRP 860
           PSRP RAPP VPSR    SP+RP   RP
Sbjct: 829 PSRPTRAPPSVPSRRPPPSPTRPTIIRP 856


>gi|209915561 dynamin 3 isoform b [Homo sapiens]
          Length = 859

 Score = 1355 bits (3507), Expect = 0.0
 Identities = 693/869 (79%), Positives = 763/869 (87%), Gaps = 26/869 (2%)

Query: 1   MGNRGMEDLIPLVNRLQDAFSAIGQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
           MGNR ME+LIPLVNRLQDAFSA+GQ+  L+LPQIAVVGGQSAGKSSVLENFVGRDFLPRG
Sbjct: 1   MGNREMEELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60

Query: 61  SGIVTRRPLVLQLVNATTEYAEFLHCKGKKFTDFEEVRLEIEAETDRVTGTNKGISPVPI 120
           SGIVTRRPLVLQLV +  EYAEFLHCKGKKFTDF+EVRLEIEAETDRVTG NKGIS +PI
Sbjct: 61  SGIVTRRPLVLQLVTSKAEYAEFLHCKGKKFTDFDEVRLEIEAETDRVTGMNKGISSIPI 120

Query: 121 NLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANSD 180
           NLRVYSPHVLNLTL+DLPG+TKVPVGDQPPDIE+QIR+M+MQF+T+ENCLILAV+PAN+D
Sbjct: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANTD 180

Query: 181 LANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240
           LANSDALK+AKEVDPQG RTIGVITKLDLMDEGTDARDVLENKLLPLRRGY+GVVNRSQK
Sbjct: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYVGVVNRSQK 240

Query: 241 DIDGKKDITAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQLTNHIRDTLPGLRNKL 300
           DIDGKKDI AA+ AERKFFLSHP+YRH+ADRMGTP+LQKVLNQQLTNHIRDTLP  RNKL
Sbjct: 241 DIDGKKDIKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQLTNHIRDTLPNFRNKL 300

Query: 301 QSQLLSIEKEVEEYKNFRPDDPARKTKALLQMVQQFAVDFEKRIEGSGDQIDTYELSGGA 360
           Q QLLSIE EVE YKNF+P+DP RKTKALLQMVQQFAVDFEKRIEGSGDQ+DT ELSGGA
Sbjct: 301 QGQLLSIEHEVEAYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGDQVDTLELSGGA 360

Query: 361 RINRIFHERFPFELVKMEFDEKELRREISYAIKNIHGIRTGLFTPDMAFETIVKKQVKKI 420
           +INRIFHERFPFE+VKMEF+EKELRREISYAIKNIHGIRTGLFTPDMAFE IVKKQ+ K+
Sbjct: 361 KINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAFEAIVKKQIVKL 420

Query: 421 REPCLKCVDMVISELISTVRQCTKKLQQYPRLREEMERIVTTHIREREGRTKEQVMLLID 480
           + P LK VD+VI ELI+TV++CTKKL  +PRL EE ERIV  HIREREG+TK+QV+LLID
Sbjct: 421 KGPSLKSVDLVIQELINTVKKCTKKLANFPRLCEETERIVANHIREREGKTKDQVLLLID 480

Query: 481 IELAYMNTNHEDFIGFANAQQRSNQMNKKKTSGNQDEILVIRKGWLTINNIGIMKGGSKE 540
           I+++Y+NTNHEDFIGFANAQQRS+Q++KK T GNQ    VIRKGWLTI+NIGIMKGGSK 
Sbjct: 481 IQVSYINTNHEDFIGFANAQQRSSQVHKKTTVGNQ----VIRKGWLTISNIGIMKGGSKG 536

Query: 541 YWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDY 600
           YWFVLTAE+LSWYKDDEEKEKKYML +DNLK+RDVEK FMSSKHIFALFNTEQRNVYKDY
Sbjct: 537 YWFVLTAESLSWYKDDEEKEKKYMLPLDNLKVRDVEKSFMSSKHIFALFNTEQRNVYKDY 596

Query: 601 RQLELACETQEEVDSWKASFLRAGVYPERVGDKEKASETEENG-SDSFMHSMDPQLERQV 659
           R LELAC++QE+VDSWKAS LRAGVYP++       +E +ENG +++F  SMDPQLERQV
Sbjct: 597 RFLELACDSQEDVDSWKASLLRAGVYPDK-----SVAENDENGQAENF--SMDPQLERQV 649

Query: 660 ETIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELLANLYSCGDQNTLMEESA 719
           ETIRNLVDSYM+I+NK +RDL+PKTIMHLMINN K+FI SELLA LYS  DQNTLMEESA
Sbjct: 650 ETIRNLVDSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLMEESA 709

Query: 720 EQAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSP 779
           EQAQRRDEMLRMY ALKEAL IIGDI+T TVSTP PPPVDDSW+Q       RRSP  SP
Sbjct: 710 EQAQRRDEMLRMYQALKEALGIIGDISTATVSTPAPPPVDDSWIQ-----HSRRSPPPSP 764

Query: 780 TPQRRAP-AVPPARPGS-RGPAPGPPPAGSALGGAPPVPSRPG------ASPDPFGPPPQ 831
           T QRR   + P ARP S RGPAP  P  G    GAPPVP RPG      +S D FG PPQ
Sbjct: 765 TTQRRPTLSAPLARPTSGRGPAPAIPSPGPH-SGAPPVPFRPGPLPPFPSSSDSFGAPPQ 823

Query: 832 VPSRPNRAPPGVPSRSGQASPSRPESPRP 860
           VPSRP RAPP VPSR    SP+RP   RP
Sbjct: 824 VPSRPTRAPPSVPSRRPPPSPTRPTIIRP 852


>gi|56549125 dynamin 2 isoform 4 [Homo sapiens]
          Length = 866

 Score = 1352 bits (3500), Expect = 0.0
 Identities = 683/877 (77%), Positives = 769/877 (87%), Gaps = 35/877 (3%)

Query: 1   MGNRGMEDLIPLVNRLQDAFSAIGQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
           MGNRGME+LIPLVN+LQDAFS+IGQ+  LDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG
Sbjct: 1   MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60

Query: 61  SGIVTRRPLVLQLVNATTEYAEFLHCKGKKFTDFEEVRLEIEAETDRVTGTNKGISPVPI 120
           SGIVTRRPL+LQL+ + TE+AEFLHCK KKFTDF+EVR EIEAETDRVTGTNKGISPVPI
Sbjct: 61  SGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPI 120

Query: 121 NLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANSD 180
           NLRVYSPHVLNLTL+DLPG+TKVPVGDQPPDIE+QI+DM++QF+++E+ LILAV+PAN D
Sbjct: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD 180

Query: 181 LANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240
           LANSDALK+AKEVDPQG RTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK
Sbjct: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240

Query: 241 DIDGKKDITAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQLTNHIRDTLPGLRNKL 300
           DI+GKKDI AALAAERKFFLSHP+YRH+ADRMGTP+LQK LNQQLTNHIR++LP LR+KL
Sbjct: 241 DIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKL 300

Query: 301 QSQLLSIEKEVEEYKNFRPDDPARKTKALLQMVQQFAVDFEKRIEGSGDQIDTYELSGGA 360
           QSQLLS+EKEVEEYKNFRPDDP RKTKALLQMVQQF VDFEKRIEGSGDQ+DT ELSGGA
Sbjct: 301 QSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGA 360

Query: 361 RINRIFHERFPFELVKMEFDEKELRREISYAIKNIHGIRTGLFTPDMAFETIVKKQVKKI 420
           RINRIFHERFPFELVKMEFDEK+LRREISYAIKNIHG+RTGLFTPDMAFE IVKKQ+ K+
Sbjct: 361 RINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAFEAIVKKQIVKL 420

Query: 421 REPCLKCVDMVISELISTVRQCTKKLQQYPRLREEMERIVTTHIREREGRTKEQVMLLID 480
           +EP LKCVD+V+SEL + +++C +KL  YPRLREE ERIVTT+IREREGRTK+Q++LLID
Sbjct: 421 KEPSLKCVDLVVSELATVIKKCAEKLSSYPRLREETERIVTTYIREREGRTKDQILLLID 480

Query: 481 IELAYMNTNHEDFIGFANAQQRSNQMNKKKTSGNQDEILVIRKGWLTINNIGIMKGGSKE 540
           IE +Y+NTNHEDFIGFANAQQRS Q+NKK+   NQ    VIR+GWLTINNI +MKGGSKE
Sbjct: 481 IEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQ----VIRRGWLTINNISLMKGGSKE 536

Query: 541 YWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDY 600
           YWFVLTAE+LSWYKD+EEKEKKYML +DNLK+RDVEKGFMS+KH+FA+FNTEQRNVYKD 
Sbjct: 537 YWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDL 596

Query: 601 RQLELACETQEEVDSWKASFLRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVE 660
           RQ+ELAC++QE+VDSWKASFLRAGVYP      EK     E+G+     SMDPQLERQVE
Sbjct: 597 RQIELACDSQEDVDSWKASFLRAGVYP------EKDQAENEDGAQENTFSMDPQLERQVE 650

Query: 661 TIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELLANLYSCGDQNTLMEESAE 720
           TIRNLVDSY+AI+NK++RDLMPKTIMHLMINNTK FI  ELLA LYS  DQ++LMEESA+
Sbjct: 651 TIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESAD 710

Query: 721 QAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPT 780
           QAQRRD+MLRMYHALKEAL+IIGDI+T+TVSTP+PPPVDD+WLQ  S        + SPT
Sbjct: 711 QAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSAS--------SHSPT 762

Query: 781 PQRR--APAVPPARPGS-RGPAPGPP----PAGSALG-GAPPVPSRPG-----ASPDPFG 827
           PQRR  +   PP RP + RGP PGPP    P G+A    APP+PSRPG     A+ D F 
Sbjct: 763 PQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFP 822

Query: 828 PPPQVPSRPNR----APPGVPSRSGQASPSRPESPRP 860
            PPQ+PSRP R     PPGVPSR   A+PSRP   RP
Sbjct: 823 APPQIPSRPVRIPPGIPPGVPSRRPPAAPSRPTIIRP 859


>gi|171460916 dynamin 1-like isoform 2 [Homo sapiens]
          Length = 710

 Score =  459 bits (1182), Expect = e-129
 Identities = 251/541 (46%), Positives = 362/541 (66%), Gaps = 34/541 (6%)

Query: 6   MEDLIPLVNRLQDAFSAIGQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVT 65
           ME LIP++N+LQD F+ +G +  + LPQI VVG QS+GKSSVLE+ VGRD LPRG+GIVT
Sbjct: 1   MEALIPVINKLQDVFNTVGADI-IQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVT 59

Query: 66  RRPLVLQLVNATTE----------------YAEFLHCKGKKFTDFEEVRLEIEAETDRVT 109
           RRPL+LQLV+ + E                + +FLH K K +TDF+E+R EIE ET+R++
Sbjct: 60  RRPLILQLVHVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIENETERIS 119

Query: 110 GTNKGISPVPINLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENC 169
           G NKG+SP PI+L+++SP+V+NLTLVDLPGMTKVPVGDQP DIE QIR+++++F++  N 
Sbjct: 120 GNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNS 179

Query: 170 LILAVSPANSDLANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDARDVLENKLLPLRR 229
           +ILAV+ AN+D+A S+ALK+++EVDP G+RT+ VITKLDLMD GTDA DVL  +++P++ 
Sbjct: 180 IILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAMDVLMGRVIPVKL 239

Query: 230 GYIGVVNRSQKDIDGKKDITAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQLTNHI 289
           G IGVVNRSQ DI+ KK +T ++  E  F      Y  LA+R GT YL + LN+ L +HI
Sbjct: 240 GIIGVVNRSQLDINNKKSVTDSIRDEYAFL--QKKYPSLANRNGTKYLARTLNRLLMHHI 297

Query: 290 RDTLPGLRNKLQSQLLSIEKEVEEYKNFRPDDPARKTKALLQMVQQFAVDFEKRIEGSGD 349
           RD LP L+ ++       +  +  Y     D    K+  LLQ++ +FA ++   IEG+  
Sbjct: 298 RDCLPELKTRINVLAAQYQSLLNSYGEPVDD----KSATLLQLITKFATEYCNTIEGTAK 353

Query: 350 QIDTYELSGGARINRIFHERFPFELVKMEFDEKELRREISYAIKNIHGIRTGLFTPDMAF 409
            I+T EL GGARI  IFHE F   L  ++        +I  AI+N  G R  LF P+++F
Sbjct: 354 YIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSF 413

Query: 410 ETIVKKQVKKIREPCLKCVDMVISELISTVRQC----TKKLQQYPRLREEMERIVTTHIR 465
           E +VK+Q+K++ EP L+CV++V  E+   ++ C    T++L ++P+L + +  +VT  +R
Sbjct: 414 ELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLR 473

Query: 466 EREGRTKEQVMLLIDIELAYMNTNHEDF---IGFAN---AQQRSNQMNKKKTSG-NQDEI 518
           +R   T E V  L+ IELAY+NT H DF    G  N    +QR N++ ++  S  ++D++
Sbjct: 474 KRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSAVSRDKL 533

Query: 519 L 519
           +
Sbjct: 534 I 534



 Score = 73.6 bits (179), Expect = 8e-13
 Identities = 37/93 (39%), Positives = 54/93 (58%)

Query: 656 ERQVETIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELLANLYSCGDQNTLM 715
           +R  E I  L+ SY  IV K ++D +PK +MH ++N+ K+ + SEL+  LY     + L+
Sbjct: 615 QRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLL 674

Query: 716 EESAEQAQRRDEMLRMYHALKEALSIIGDINTT 748
            ES + AQRR E   M  AL+ A  II +I  T
Sbjct: 675 TESEDMAQRRKEAADMLKALQGASQIIAEIRET 707


>gi|171460914 dynamin 1-like isoform 1 [Homo sapiens]
          Length = 736

 Score =  459 bits (1181), Expect = e-129
 Identities = 250/533 (46%), Positives = 356/533 (66%), Gaps = 33/533 (6%)

Query: 6   MEDLIPLVNRLQDAFSAIGQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVT 65
           ME LIP++N+LQD F+ +G +  + LPQI VVG QS+GKSSVLE+ VGRD LPRG+GIVT
Sbjct: 1   MEALIPVINKLQDVFNTVGADI-IQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVT 59

Query: 66  RRPLVLQLVNATTE----------------YAEFLHCKGKKFTDFEEVRLEIEAETDRVT 109
           RRPL+LQLV+ + E                + +FLH K K +TDF+E+R EIE ET+R++
Sbjct: 60  RRPLILQLVHVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIENETERIS 119

Query: 110 GTNKGISPVPINLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENC 169
           G NKG+SP PI+L+++SP+V+NLTLVDLPGMTKVPVGDQP DIE QIR+++++F++  N 
Sbjct: 120 GNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNS 179

Query: 170 LILAVSPANSDLANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDARDVLENKLLPLRR 229
           +ILAV+ AN+D+A S+ALK+++EVDP G+RT+ VITKLDLMD GTDA DVL  +++P++ 
Sbjct: 180 IILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAMDVLMGRVIPVKL 239

Query: 230 GYIGVVNRSQKDIDGKKDITAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQLTNHI 289
           G IGVVNRSQ DI+ KK +T ++  E  F      Y  LA+R GT YL + LN+ L +HI
Sbjct: 240 GIIGVVNRSQLDINNKKSVTDSIRDEYAFL--QKKYPSLANRNGTKYLARTLNRLLMHHI 297

Query: 290 RDTLPGLRNKLQSQLLSIEKEVEEYKNFRPDDPARKTKALLQMVQQFAVDFEKRIEGSGD 349
           RD LP L+ ++       +  +  Y     D    K+  LLQ++ +FA ++   IEG+  
Sbjct: 298 RDCLPELKTRINVLAAQYQSLLNSYGEPVDD----KSATLLQLITKFATEYCNTIEGTAK 353

Query: 350 QIDTYELSGGARINRIFHERFPFELVKMEFDEKELRREISYAIKNIHGIRTGLFTPDMAF 409
            I+T EL GGARI  IFHE F   L  ++        +I  AI+N  G R  LF P+++F
Sbjct: 354 YIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSF 413

Query: 410 ETIVKKQVKKIREPCLKCVDMVISELISTVRQC----TKKLQQYPRLREEMERIVTTHIR 465
           E +VK+Q+K++ EP L+CV++V  E+   ++ C    T++L ++P+L + +  +VT  +R
Sbjct: 414 ELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLR 473

Query: 466 EREGRTKEQVMLLIDIELAYMNTNHEDF---IGFAN---AQQRSNQMNKKKTS 512
           +R   T E V  L+ IELAY+NT H DF    G  N    +QR N++ ++  S
Sbjct: 474 KRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPS 526



 Score = 73.6 bits (179), Expect = 8e-13
 Identities = 37/93 (39%), Positives = 54/93 (58%)

Query: 656 ERQVETIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELLANLYSCGDQNTLM 715
           +R  E I  L+ SY  IV K ++D +PK +MH ++N+ K+ + SEL+  LY     + L+
Sbjct: 641 QRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLL 700

Query: 716 EESAEQAQRRDEMLRMYHALKEALSIIGDINTT 748
            ES + AQRR E   M  AL+ A  II +I  T
Sbjct: 701 TESEDMAQRRKEAADMLKALQGASQIIAEIRET 733


>gi|171460918 dynamin 1-like isoform 3 [Homo sapiens]
          Length = 699

 Score =  459 bits (1181), Expect = e-129
 Identities = 250/533 (46%), Positives = 356/533 (66%), Gaps = 33/533 (6%)

Query: 6   MEDLIPLVNRLQDAFSAIGQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVT 65
           ME LIP++N+LQD F+ +G +  + LPQI VVG QS+GKSSVLE+ VGRD LPRG+GIVT
Sbjct: 1   MEALIPVINKLQDVFNTVGADI-IQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVT 59

Query: 66  RRPLVLQLVNATTE----------------YAEFLHCKGKKFTDFEEVRLEIEAETDRVT 109
           RRPL+LQLV+ + E                + +FLH K K +TDF+E+R EIE ET+R++
Sbjct: 60  RRPLILQLVHVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIENETERIS 119

Query: 110 GTNKGISPVPINLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENC 169
           G NKG+SP PI+L+++SP+V+NLTLVDLPGMTKVPVGDQP DIE QIR+++++F++  N 
Sbjct: 120 GNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNS 179

Query: 170 LILAVSPANSDLANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDARDVLENKLLPLRR 229
           +ILAV+ AN+D+A S+ALK+++EVDP G+RT+ VITKLDLMD GTDA DVL  +++P++ 
Sbjct: 180 IILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAMDVLMGRVIPVKL 239

Query: 230 GYIGVVNRSQKDIDGKKDITAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQLTNHI 289
           G IGVVNRSQ DI+ KK +T ++  E  F      Y  LA+R GT YL + LN+ L +HI
Sbjct: 240 GIIGVVNRSQLDINNKKSVTDSIRDEYAFL--QKKYPSLANRNGTKYLARTLNRLLMHHI 297

Query: 290 RDTLPGLRNKLQSQLLSIEKEVEEYKNFRPDDPARKTKALLQMVQQFAVDFEKRIEGSGD 349
           RD LP L+ ++       +  +  Y     D    K+  LLQ++ +FA ++   IEG+  
Sbjct: 298 RDCLPELKTRINVLAAQYQSLLNSYGEPVDD----KSATLLQLITKFATEYCNTIEGTAK 353

Query: 350 QIDTYELSGGARINRIFHERFPFELVKMEFDEKELRREISYAIKNIHGIRTGLFTPDMAF 409
            I+T EL GGARI  IFHE F   L  ++        +I  AI+N  G R  LF P+++F
Sbjct: 354 YIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSF 413

Query: 410 ETIVKKQVKKIREPCLKCVDMVISELISTVRQC----TKKLQQYPRLREEMERIVTTHIR 465
           E +VK+Q+K++ EP L+CV++V  E+   ++ C    T++L ++P+L + +  +VT  +R
Sbjct: 414 ELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLR 473

Query: 466 EREGRTKEQVMLLIDIELAYMNTNHEDF---IGFAN---AQQRSNQMNKKKTS 512
           +R   T E V  L+ IELAY+NT H DF    G  N    +QR N++ ++  S
Sbjct: 474 KRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPS 526



 Score = 73.6 bits (179), Expect = 8e-13
 Identities = 37/93 (39%), Positives = 54/93 (58%)

Query: 656 ERQVETIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELLANLYSCGDQNTLM 715
           +R  E I  L+ SY  IV K ++D +PK +MH ++N+ K+ + SEL+  LY     + L+
Sbjct: 604 QRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLL 663

Query: 716 EESAEQAQRRDEMLRMYHALKEALSIIGDINTT 748
            ES + AQRR E   M  AL+ A  II +I  T
Sbjct: 664 TESEDMAQRRKEAADMLKALQGASQIIAEIRET 696


>gi|222136619 myxovirus resistance protein 1 [Homo sapiens]
          Length = 662

 Score =  238 bits (606), Expect = 2e-62
 Identities = 156/428 (36%), Positives = 237/428 (55%), Gaps = 21/428 (4%)

Query: 16  LQDAFSAIGQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLVLQLVN 75
           L D+  A+G   DL LP IAV+G QS+GKSSVLE   G   LPRGSGIVTR PLVL+L  
Sbjct: 55  LIDSLRALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVA-LPRGSGIVTRCPLVLKLKK 113

Query: 76  ATTEYAEFLHCKGK--------KFTDFEEVRLEIEAETDRVTGTNKGISPVPINLRVYSP 127
              E       +GK        + +D  EV  EI    + + G   GIS   I L + S 
Sbjct: 114 LVNEDK----WRGKVSYQDYEIEISDASEVEKEINKAQNAIAGEGMGISHELITLEISSR 169

Query: 128 HVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANSDLANSDAL 187
            V +LTL+DLPG+T+V VG+QP DI ++I+ ++ +++ ++  + L V P+N D+A ++AL
Sbjct: 170 DVPDLTLIDLPGITRVAVGNQPADIGYKIKTLIKKYIQRQETISLVVVPSNVDIATTEAL 229

Query: 188 KVAKEVDPQGQRTIGVITKLDLMDEGTDAR--DVLENKLLPLRRGYIGVVNRSQKDIDGK 245
            +A+EVDP+G RTIG++TK DL+D+GT+ +  DV+ N +  L++GY+ V  R Q++I  +
Sbjct: 230 SMAQEVDPEGDRTIGILTKPDLVDKGTEDKVVDVVRNLVFHLKKGYMIVKCRGQQEIQDQ 289

Query: 246 KDITAALAAERKFFLSHPSYRHLAD--RMGTPYLQKVLNQQLTNHIRDTLPGLRNKLQSQ 303
             ++ AL  E+ FF +HP +R L +  +   P L + L  +L  HI  +LP L N+++  
Sbjct: 290 LSLSEALQREKIFFENHPYFRDLLEEGKATVPCLAEKLTSELITHICKSLPLLENQIKET 349

Query: 304 LLSIEKEVEEYKNFRPDDPARKTKALLQMVQQFAVDFEKRIEGSGDQIDTYELSGGARIN 363
              I +E+++Y    P+D   K   L+  V  F  D    ++G  + +   ++    R+ 
Sbjct: 350 HQRITEELQKYGVDIPEDENEKMFFLIDKVNAFNQDITALMQGE-ETVGEEDIRLFTRLR 408

Query: 364 RIFHERFPFELVKMEFDEKELRREISYAIKNIHGIRTGLFTPDMAFETIVKKQVKKIREP 423
             FH+         +   K L R+I        G     F     FETIVK+Q+K + EP
Sbjct: 409 HEFHKWSTIIENNFQEGHKILSRKIQKFENQYRGRELPGFVNYRTFETIVKQQIKALEEP 468

Query: 424 CLKCVDMV 431
               VDM+
Sbjct: 469 ---AVDML 473


>gi|222136617 myxovirus resistance protein 1 [Homo sapiens]
          Length = 662

 Score =  238 bits (606), Expect = 2e-62
 Identities = 156/428 (36%), Positives = 237/428 (55%), Gaps = 21/428 (4%)

Query: 16  LQDAFSAIGQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLVLQLVN 75
           L D+  A+G   DL LP IAV+G QS+GKSSVLE   G   LPRGSGIVTR PLVL+L  
Sbjct: 55  LIDSLRALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVA-LPRGSGIVTRCPLVLKLKK 113

Query: 76  ATTEYAEFLHCKGK--------KFTDFEEVRLEIEAETDRVTGTNKGISPVPINLRVYSP 127
              E       +GK        + +D  EV  EI    + + G   GIS   I L + S 
Sbjct: 114 LVNEDK----WRGKVSYQDYEIEISDASEVEKEINKAQNAIAGEGMGISHELITLEISSR 169

Query: 128 HVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANSDLANSDAL 187
            V +LTL+DLPG+T+V VG+QP DI ++I+ ++ +++ ++  + L V P+N D+A ++AL
Sbjct: 170 DVPDLTLIDLPGITRVAVGNQPADIGYKIKTLIKKYIQRQETISLVVVPSNVDIATTEAL 229

Query: 188 KVAKEVDPQGQRTIGVITKLDLMDEGTDAR--DVLENKLLPLRRGYIGVVNRSQKDIDGK 245
            +A+EVDP+G RTIG++TK DL+D+GT+ +  DV+ N +  L++GY+ V  R Q++I  +
Sbjct: 230 SMAQEVDPEGDRTIGILTKPDLVDKGTEDKVVDVVRNLVFHLKKGYMIVKCRGQQEIQDQ 289

Query: 246 KDITAALAAERKFFLSHPSYRHLAD--RMGTPYLQKVLNQQLTNHIRDTLPGLRNKLQSQ 303
             ++ AL  E+ FF +HP +R L +  +   P L + L  +L  HI  +LP L N+++  
Sbjct: 290 LSLSEALQREKIFFENHPYFRDLLEEGKATVPCLAEKLTSELITHICKSLPLLENQIKET 349

Query: 304 LLSIEKEVEEYKNFRPDDPARKTKALLQMVQQFAVDFEKRIEGSGDQIDTYELSGGARIN 363
              I +E+++Y    P+D   K   L+  V  F  D    ++G  + +   ++    R+ 
Sbjct: 350 HQRITEELQKYGVDIPEDENEKMFFLIDKVNAFNQDITALMQGE-ETVGEEDIRLFTRLR 408

Query: 364 RIFHERFPFELVKMEFDEKELRREISYAIKNIHGIRTGLFTPDMAFETIVKKQVKKIREP 423
             FH+         +   K L R+I        G     F     FETIVK+Q+K + EP
Sbjct: 409 HEFHKWSTIIENNFQEGHKILSRKIQKFENQYRGRELPGFVNYRTFETIVKQQIKALEEP 468

Query: 424 CLKCVDMV 431
               VDM+
Sbjct: 469 ---AVDML 473


>gi|11342664 myxovirus resistance protein 2 [Homo sapiens]
          Length = 715

 Score =  215 bits (547), Expect = 2e-55
 Identities = 151/440 (34%), Positives = 234/440 (53%), Gaps = 19/440 (4%)

Query: 16  LQDAFSAIGQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLVLQLVN 75
           L D+  A+G   DL LP IAV+G QS+GKSSVLE   G   LPRGSGIVTR PLVL+L  
Sbjct: 103 LIDSLRALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVA-LPRGSGIVTRCPLVLKLKK 161

Query: 76  ATTE-YAEFLHCKGKKFT--DFEEVRLEIEAETDRVTGTNKGISPVPINLRVYSPHVLNL 132
              E +A  +  +  +    D  +V  EI    + + G  +GIS   I+L + SP V +L
Sbjct: 162 QPCEAWAGRISYRNTELELQDPGQVEKEIHKAQNVMAGNGRGISHELISLEITSPEVPDL 221

Query: 133 TLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANSDLANSDALKVAKE 192
           T++DLPG+T+V V +QP DI  QI+ ++ +++ ++  + L V P N D+A ++AL +A E
Sbjct: 222 TIIDLPGITRVAVDNQPRDIGLQIKALIKKYIQRQQTINLVVVPCNVDIATTEALSMAHE 281

Query: 193 VDPQGQRTIGVITKLDLMDEGTD--ARDVLENKLLPLRRGYIGVVNRSQKDIDGKKDITA 250
           VDP+G RTIG++TK DLMD GT+    +V+ N   PL++GY+ V  R Q++I  +  +  
Sbjct: 282 VDPEGDRTIGILTKPDLMDRGTEKSVMNVVRNLTYPLKKGYMIVKCRGQQEITNRLSLAE 341

Query: 251 ALAAERKFFLSHPSYRHLADR--MGTPYLQKVLNQQLTNHIRDTLPGLRNKLQSQLLSIE 308
           A   E  FF +HP +R L +      P L + L  +L  HI+ +LP L  +++    S +
Sbjct: 342 ATKKEITFFQTHPYFRVLLEEGSATVPRLAERLTTELIMHIQKSLPLLEGQIRE---SHQ 398

Query: 309 KEVEEYKNFRPDDP---ARKTKALLQMVQQFAVDFEKRIEGSGDQIDTYELSGGARINRI 365
           K  EE +    D P   A K   L++ ++ F  D EK +EG  + +   E     +I   
Sbjct: 399 KATEELRRCGADIPSQEADKMFFLIEKIKMFNQDIEKLVEGE-EVVRENETRLYNKIRED 457

Query: 366 FHERFPFELVKMEFDEKELRREISYAIKNIHGIRTGLFTPDMAFETIVKKQVKKIREPCL 425
           F           +  +  +  E+    K   G     F     FE IV + ++++ EP L
Sbjct: 458 FKNWVGILATNTQKVKNIIHEEVEKYEKQYRGKELLGFVNYKTFEIIVHQYIQQLVEPAL 517

Query: 426 ----KCVDMVISELISTVRQ 441
               K ++++    I+  ++
Sbjct: 518 SMLQKAMEIIQQAFINVAKK 537


>gi|239756350 PREDICTED: UPF0621 protein C-like [Homo sapiens]
          Length = 135

 Score =  162 bits (410), Expect = 1e-39
 Identities = 86/123 (69%), Positives = 99/123 (80%), Gaps = 4/123 (3%)

Query: 635 KASETEENGSDSFMHSMDPQLERQVETIRNLVDSYMAIVNKTVRDLM----PKTIMHLMI 690
           +AS+ EENGSDSFMHSMDPQL  Q+ET ++LVDSY+AIVNKTV DLM    PKT MHLMI
Sbjct: 8   QASKAEENGSDSFMHSMDPQLVWQMETTQSLVDSYVAIVNKTVWDLMVGLTPKTTMHLMI 67

Query: 691 NNTKEFIFSELLANLYSCGDQNTLMEESAEQAQRRDEMLRMYHALKEALSIIGDINTTTV 750
           NN  EFIFSELLA LYSCGD+N LME+S EQA+  +E L M+H L+EA +IIGDI TT V
Sbjct: 68  NNMHEFIFSELLAKLYSCGDENMLMEDSTEQAKWCNETLCMHHVLREAPNIIGDIKTTMV 127

Query: 751 STP 753
           S P
Sbjct: 128 SMP 130


>gi|239750876 PREDICTED: UPF0621 protein C-like [Homo sapiens]
          Length = 135

 Score =  162 bits (410), Expect = 1e-39
 Identities = 86/123 (69%), Positives = 99/123 (80%), Gaps = 4/123 (3%)

Query: 635 KASETEENGSDSFMHSMDPQLERQVETIRNLVDSYMAIVNKTVRDLM----PKTIMHLMI 690
           +AS+ EENGSDSFMHSMDPQL  Q+ET ++LVDSY+AIVNKTV DLM    PKT MHLMI
Sbjct: 8   QASKAEENGSDSFMHSMDPQLVWQMETTQSLVDSYVAIVNKTVWDLMVGLTPKTTMHLMI 67

Query: 691 NNTKEFIFSELLANLYSCGDQNTLMEESAEQAQRRDEMLRMYHALKEALSIIGDINTTTV 750
           NN  EFIFSELLA LYSCGD+N LME+S EQA+  +E L M+H L+EA +IIGDI TT V
Sbjct: 68  NNMHEFIFSELLAKLYSCGDENMLMEDSTEQAKWCNETLCMHHVLREAPNIIGDIKTTMV 127

Query: 751 STP 753
           S P
Sbjct: 128 SMP 130


>gi|169208224 PREDICTED: UPF0621 protein C-like [Homo sapiens]
          Length = 155

 Score =  162 bits (410), Expect = 1e-39
 Identities = 86/123 (69%), Positives = 99/123 (80%), Gaps = 4/123 (3%)

Query: 635 KASETEENGSDSFMHSMDPQLERQVETIRNLVDSYMAIVNKTVRDLM----PKTIMHLMI 690
           +AS+ EENGSDSFMHSMDPQL  Q+ET ++LVDSY+AIVNKTV DLM    PKT MHLMI
Sbjct: 28  QASKAEENGSDSFMHSMDPQLVWQMETTQSLVDSYVAIVNKTVWDLMVGLTPKTTMHLMI 87

Query: 691 NNTKEFIFSELLANLYSCGDQNTLMEESAEQAQRRDEMLRMYHALKEALSIIGDINTTTV 750
           NN  EFIFSELLA LYSCGD+N LME+S EQA+  +E L M+H L+EA +IIGDI TT V
Sbjct: 88  NNMHEFIFSELLAKLYSCGDENMLMEDSTEQAKWCNETLCMHHVLREAPNIIGDIKTTMV 147

Query: 751 STP 753
           S P
Sbjct: 148 SMP 150


>gi|113425405 PREDICTED: similar to dynamin 1 [Homo sapiens]
          Length = 105

 Score =  122 bits (305), Expect = 2e-27
 Identities = 64/102 (62%), Positives = 73/102 (71%), Gaps = 11/102 (10%)

Query: 705 LYSCGDQNTLMEESAEQAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQ 764
           +YSCG+QNTLMEE AEQAQ+ DEML M+HALKEALSIIGDIN TTV+ PMPPPVDD+WLQ
Sbjct: 1   MYSCGNQNTLMEELAEQAQQHDEMLHMHHALKEALSIIGDINRTTVTMPMPPPVDDTWLQ 60

Query: 765 VQSVPAGRR----SPTSSPTPQR-------RAPAVPPARPGS 795
           VQS+P   R     PT+  +P R        A   PP R GS
Sbjct: 61  VQSIPDAHRYQRLPPTAPKSPTRDAQRSALGASGTPPHRGGS 102


>gi|239745286 PREDICTED: hypothetical protein XP_002343417 [Homo
           sapiens]
          Length = 103

 Score =  114 bits (286), Expect = 3e-25
 Identities = 63/102 (61%), Positives = 72/102 (70%), Gaps = 13/102 (12%)

Query: 705 LYSCGDQNTLMEESAEQAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQ 764
           +YSCG+QNTLMEE AEQAQ+ DEML M+HALKEALSIIGDIN TTV+  MPPPVDD+WLQ
Sbjct: 1   MYSCGNQNTLMEELAEQAQQHDEMLHMHHALKEALSIIGDINRTTVT--MPPPVDDTWLQ 58

Query: 765 VQSVPAGRR----SPTSSPTPQRRA-------PAVPPARPGS 795
           VQS+P   R     PT+  +P R A          PP R GS
Sbjct: 59  VQSIPDAHRYQRLPPTAPKSPTRDAQRSALGTSGTPPHRGGS 100


>gi|224831253 optic atrophy 1 isoform 8 [Homo sapiens]
          Length = 1015

 Score =  107 bits (267), Expect = 5e-23
 Identities = 80/265 (30%), Positives = 123/265 (46%), Gaps = 15/265 (5%)

Query: 7   EDLIPLVNRLQDAFSAI--GQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSG-I 63
           + LI + + + D  S      N    LP++ VVG QSAGK+SVLE        PRGSG +
Sbjct: 317 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 376

Query: 64  VTRRPLVLQLVNATTEYAEFLHCKGK----KFTDFEEVRLEIEAETDRVTGTNKGISPVP 119
           +TR P+ + L       A F     +    K  D   +R EIE    +       +SP  
Sbjct: 377 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 436

Query: 120 INLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANS 179
           I+L V  P +  + LVDLPG+         PD +  I  +   ++   N +IL +   + 
Sbjct: 437 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 496

Query: 180 DLANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYIGV 234
           D   S    +  ++DP G+RTI V+TK+DL ++   +    + ++E KL P++  GY  V
Sbjct: 497 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 556

Query: 235 VNRSQKDIDGKKDITAALAAERKFF 259
           V       +  + I A    E +FF
Sbjct: 557 VTGKG---NSSESIEAIREYEEEFF 578


>gi|224831251 optic atrophy 1 isoform 7 [Homo sapiens]
          Length = 997

 Score =  107 bits (267), Expect = 5e-23
 Identities = 80/265 (30%), Positives = 123/265 (46%), Gaps = 15/265 (5%)

Query: 7   EDLIPLVNRLQDAFSAI--GQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSG-I 63
           + LI + + + D  S      N    LP++ VVG QSAGK+SVLE        PRGSG +
Sbjct: 299 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 358

Query: 64  VTRRPLVLQLVNATTEYAEFLHCKGK----KFTDFEEVRLEIEAETDRVTGTNKGISPVP 119
           +TR P+ + L       A F     +    K  D   +R EIE    +       +SP  
Sbjct: 359 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 418

Query: 120 INLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANS 179
           I+L V  P +  + LVDLPG+         PD +  I  +   ++   N +IL +   + 
Sbjct: 419 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 478

Query: 180 DLANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYIGV 234
           D   S    +  ++DP G+RTI V+TK+DL ++   +    + ++E KL P++  GY  V
Sbjct: 479 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 538

Query: 235 VNRSQKDIDGKKDITAALAAERKFF 259
           V       +  + I A    E +FF
Sbjct: 539 VTGKG---NSSESIEAIREYEEEFF 560


>gi|18860841 optic atrophy 1 isoform 6 [Homo sapiens]
          Length = 979

 Score =  107 bits (267), Expect = 5e-23
 Identities = 80/265 (30%), Positives = 123/265 (46%), Gaps = 15/265 (5%)

Query: 7   EDLIPLVNRLQDAFSAI--GQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSG-I 63
           + LI + + + D  S      N    LP++ VVG QSAGK+SVLE        PRGSG +
Sbjct: 281 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 340

Query: 64  VTRRPLVLQLVNATTEYAEFLHCKGK----KFTDFEEVRLEIEAETDRVTGTNKGISPVP 119
           +TR P+ + L       A F     +    K  D   +R EIE    +       +SP  
Sbjct: 341 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 400

Query: 120 INLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANS 179
           I+L V  P +  + LVDLPG+         PD +  I  +   ++   N +IL +   + 
Sbjct: 401 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 460

Query: 180 DLANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYIGV 234
           D   S    +  ++DP G+RTI V+TK+DL ++   +    + ++E KL P++  GY  V
Sbjct: 461 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 520

Query: 235 VNRSQKDIDGKKDITAALAAERKFF 259
           V       +  + I A    E +FF
Sbjct: 521 VTGKG---NSSESIEAIREYEEEFF 542


>gi|224831248 optic atrophy 1 isoform 5 [Homo sapiens]
          Length = 978

 Score =  107 bits (267), Expect = 5e-23
 Identities = 80/265 (30%), Positives = 123/265 (46%), Gaps = 15/265 (5%)

Query: 7   EDLIPLVNRLQDAFSAI--GQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSG-I 63
           + LI + + + D  S      N    LP++ VVG QSAGK+SVLE        PRGSG +
Sbjct: 280 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 339

Query: 64  VTRRPLVLQLVNATTEYAEFLHCKGK----KFTDFEEVRLEIEAETDRVTGTNKGISPVP 119
           +TR P+ + L       A F     +    K  D   +R EIE    +       +SP  
Sbjct: 340 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 399

Query: 120 INLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANS 179
           I+L V  P +  + LVDLPG+         PD +  I  +   ++   N +IL +   + 
Sbjct: 400 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 459

Query: 180 DLANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYIGV 234
           D   S    +  ++DP G+RTI V+TK+DL ++   +    + ++E KL P++  GY  V
Sbjct: 460 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 519

Query: 235 VNRSQKDIDGKKDITAALAAERKFF 259
           V       +  + I A    E +FF
Sbjct: 520 VTGKG---NSSESIEAIREYEEEFF 541


>gi|18860835 optic atrophy 1 isoform 4 [Homo sapiens]
          Length = 961

 Score =  107 bits (267), Expect = 5e-23
 Identities = 80/265 (30%), Positives = 123/265 (46%), Gaps = 15/265 (5%)

Query: 7   EDLIPLVNRLQDAFSAI--GQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSG-I 63
           + LI + + + D  S      N    LP++ VVG QSAGK+SVLE        PRGSG +
Sbjct: 263 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 322

Query: 64  VTRRPLVLQLVNATTEYAEFLHCKGK----KFTDFEEVRLEIEAETDRVTGTNKGISPVP 119
           +TR P+ + L       A F     +    K  D   +R EIE    +       +SP  
Sbjct: 323 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 382

Query: 120 INLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANS 179
           I+L V  P +  + LVDLPG+         PD +  I  +   ++   N +IL +   + 
Sbjct: 383 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 442

Query: 180 DLANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYIGV 234
           D   S    +  ++DP G+RTI V+TK+DL ++   +    + ++E KL P++  GY  V
Sbjct: 443 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 502

Query: 235 VNRSQKDIDGKKDITAALAAERKFF 259
           V       +  + I A    E +FF
Sbjct: 503 VTGKG---NSSESIEAIREYEEEFF 524


>gi|18860833 optic atrophy 1 isoform 3 [Homo sapiens]
          Length = 942

 Score =  107 bits (267), Expect = 5e-23
 Identities = 80/265 (30%), Positives = 123/265 (46%), Gaps = 15/265 (5%)

Query: 7   EDLIPLVNRLQDAFSAI--GQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSG-I 63
           + LI + + + D  S      N    LP++ VVG QSAGK+SVLE        PRGSG +
Sbjct: 244 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 303

Query: 64  VTRRPLVLQLVNATTEYAEFLHCKGK----KFTDFEEVRLEIEAETDRVTGTNKGISPVP 119
           +TR P+ + L       A F     +    K  D   +R EIE    +       +SP  
Sbjct: 304 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 363

Query: 120 INLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANS 179
           I+L V  P +  + LVDLPG+         PD +  I  +   ++   N +IL +   + 
Sbjct: 364 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 423

Query: 180 DLANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYIGV 234
           D   S    +  ++DP G+RTI V+TK+DL ++   +    + ++E KL P++  GY  V
Sbjct: 424 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 483

Query: 235 VNRSQKDIDGKKDITAALAAERKFF 259
           V       +  + I A    E +FF
Sbjct: 484 VTGKG---NSSESIEAIREYEEEFF 505


>gi|18860831 optic atrophy 1 isoform 2 [Homo sapiens]
          Length = 924

 Score =  107 bits (267), Expect = 5e-23
 Identities = 80/265 (30%), Positives = 123/265 (46%), Gaps = 15/265 (5%)

Query: 7   EDLIPLVNRLQDAFSAI--GQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSG-I 63
           + LI + + + D  S      N    LP++ VVG QSAGK+SVLE        PRGSG +
Sbjct: 226 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 285

Query: 64  VTRRPLVLQLVNATTEYAEFLHCKGK----KFTDFEEVRLEIEAETDRVTGTNKGISPVP 119
           +TR P+ + L       A F     +    K  D   +R EIE    +       +SP  
Sbjct: 286 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 345

Query: 120 INLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANS 179
           I+L V  P +  + LVDLPG+         PD +  I  +   ++   N +IL +   + 
Sbjct: 346 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 405

Query: 180 DLANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYIGV 234
           D   S    +  ++DP G+RTI V+TK+DL ++   +    + ++E KL P++  GY  V
Sbjct: 406 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 465

Query: 235 VNRSQKDIDGKKDITAALAAERKFF 259
           V       +  + I A    E +FF
Sbjct: 466 VTGKG---NSSESIEAIREYEEEFF 487


>gi|224831243 optic atrophy 1 isoform 1 [Homo sapiens]
          Length = 960

 Score =  107 bits (267), Expect = 5e-23
 Identities = 80/265 (30%), Positives = 123/265 (46%), Gaps = 15/265 (5%)

Query: 7   EDLIPLVNRLQDAFSAI--GQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSG-I 63
           + LI + + + D  S      N    LP++ VVG QSAGK+SVLE        PRGSG +
Sbjct: 262 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 321

Query: 64  VTRRPLVLQLVNATTEYAEFLHCKGK----KFTDFEEVRLEIEAETDRVTGTNKGISPVP 119
           +TR P+ + L       A F     +    K  D   +R EIE    +       +SP  
Sbjct: 322 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 381

Query: 120 INLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANS 179
           I+L V  P +  + LVDLPG+         PD +  I  +   ++   N +IL +   + 
Sbjct: 382 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 441

Query: 180 DLANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYIGV 234
           D   S    +  ++DP G+RTI V+TK+DL ++   +    + ++E KL P++  GY  V
Sbjct: 442 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 501

Query: 235 VNRSQKDIDGKKDITAALAAERKFF 259
           V       +  + I A    E +FF
Sbjct: 502 VTGKG---NSSESIEAIREYEEEFF 523


>gi|239745270 PREDICTED: hypothetical protein XP_002343416 [Homo
           sapiens]
          Length = 63

 Score =  104 bits (259), Expect = 4e-22
 Identities = 48/59 (81%), Positives = 54/59 (91%)

Query: 705 LYSCGDQNTLMEESAEQAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWL 763
           +YSCG+QNTLMEE AEQAQ+ DEML M+HALKEALSIIGDIN TTV+ PMPPPVDD+WL
Sbjct: 1   MYSCGNQNTLMEELAEQAQQHDEMLHMHHALKEALSIIGDINRTTVTMPMPPPVDDTWL 59


>gi|239745262 PREDICTED: hypothetical protein XP_002343372 [Homo
           sapiens]
          Length = 63

 Score =  104 bits (259), Expect = 4e-22
 Identities = 48/59 (81%), Positives = 54/59 (91%)

Query: 705 LYSCGDQNTLMEESAEQAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWL 763
           +YSCG+QNTLMEE AEQAQ+ DEML M+HALKEALSIIGDIN TTV+ PMPPPVDD+WL
Sbjct: 1   MYSCGNQNTLMEELAEQAQQHDEMLHMHHALKEALSIIGDINRTTVTMPMPPPVDDTWL 59


>gi|157168329 formin 1 [Homo sapiens]
          Length = 1196

 Score = 60.8 bits (146), Expect = 5e-09
 Identities = 39/111 (35%), Positives = 45/111 (40%), Gaps = 10/111 (9%)

Query: 751 STPMPPPVDDSWLQVQSVPAGRRSPTSSPTPQRRAPAVPPARPGSRGPAPGPPPAGSALG 810
           S P PPP+      +   P         P P    P  P   P S GP P PPP      
Sbjct: 651 SIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPP------ 704

Query: 811 GAPPVPSRPGASPDPFGPPPQVPSRPNRAPPGVPSRSGQASPSRPESPRPP 861
             PP+P+ P A P+P GPPP  P  P  APP  P        S  + PR P
Sbjct: 705 --PPLPNSP-APPNPGGPPP-APPPPGLAPPPPPGLFFGLGSSSSQCPRKP 751



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 63/261 (24%), Positives = 93/261 (35%), Gaps = 52/261 (19%)

Query: 603 LELACETQEEVDSWKASF-LRA-GVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVE 660
           L L  E +EE+++ +A F LRA  +  E      +  ET EN      H      E + +
Sbjct: 504 LHLKREHKEEIENLQAQFELRAFHIRGEHAMITARLEETIENLKHELEHRWRGGCEERKD 563

Query: 661 TIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELLANLYSCGDQNTLMEESAE 720
              +  D           D  PKT  ++ +   +E         L  C        ES  
Sbjct: 564 VCISTDD-----------DCPPKTFRNVCVQTDRETF-------LKPC--------ESES 597

Query: 721 QAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPT 780
           +  R ++++               +N +++S  + PP D      + + A  +      +
Sbjct: 598 KTTRSNQLVPK------------KLNISSLSQ-LSPPNDH-----KDIHAALQPMEGMAS 639

Query: 781 PQRRAPAVPPARPGSRGPAPGPPPAGSALGGAPPVPSRPGASPDPFGPPPQVPSRPNRAP 840
            Q++A   PPA        P PPP  S LG   P P  P  S  P  PPP  P  P   P
Sbjct: 640 NQQKALPPPPAS------IPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPP 693

Query: 841 PGVPSRSGQASPSRPESPRPP 861
                      P  P SP PP
Sbjct: 694 SSAGPPPPPPPPPLPNSPAPP 714


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.134    0.388 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,784,218
Number of Sequences: 37866
Number of extensions: 2127234
Number of successful extensions: 40041
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 654
Number of HSP's successfully gapped in prelim test: 1807
Number of HSP's that attempted gapping in prelim test: 15375
Number of HSP's gapped (non-prelim): 13768
length of query: 864
length of database: 18,247,518
effective HSP length: 111
effective length of query: 753
effective length of database: 14,044,392
effective search space: 10575427176
effective search space used: 10575427176
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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