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Search of human proteins with 59814411
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|59814411 hypothetical protein LOC253725 [Homo sapiens]
(1318 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|59814411 hypothetical protein LOC253725 [Homo sapiens] 2601 0.0
gi|54124343 hypothetical protein LOC387680 [Homo sapiens] 2549 0.0
gi|154090959 hypothetical protein LOC55747 [Homo sapiens] 2351 0.0
gi|169190542 PREDICTED: hypothetical protein [Homo sapiens] 613 e-175
gi|169194762 PREDICTED: hypothetical protein [Homo sapiens] 91 6e-18
gi|239753231 PREDICTED: ankyrin repeat domain 36 [Homo sapiens] 64 7e-10
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 64 7e-10
gi|217330641 IWS1 homolog [Homo sapiens] 63 2e-09
gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens] 62 5e-09
gi|56676397 ankyrin repeat domain 11 [Homo sapiens] 61 6e-09
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 60 1e-08
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 57 1e-07
gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens] 56 2e-07
gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH po... 56 3e-07
gi|55741677 SET domain containing 1A [Homo sapiens] 56 3e-07
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 56 3e-07
gi|104526627 triadin [Homo sapiens] 56 3e-07
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu... 55 4e-07
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 55 4e-07
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 55 4e-07
gi|19913408 DNA topoisomerase II, beta isozyme [Homo sapiens] 52 3e-06
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 52 4e-06
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 51 8e-06
gi|239747798 PREDICTED: hypothetical protein XP_002348316 [Homo ... 50 1e-05
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre... 50 2e-05
gi|150170670 piccolo isoform 2 [Homo sapiens] 50 2e-05
gi|150378539 piccolo isoform 1 [Homo sapiens] 50 2e-05
gi|145199237 transcription elongation factor B polypeptide 3 bin... 50 2e-05
gi|217035154 RCSD domain containing 1 [Homo sapiens] 49 2e-05
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 49 3e-05
>gi|59814411 hypothetical protein LOC253725 [Homo sapiens]
Length = 1318
Score = 2601 bits (6742), Expect = 0.0
Identities = 1318/1318 (100%), Positives = 1318/1318 (100%)
Query: 1 MMNRTTPDQELVPASEPVWERPWSVEEIRRSSQSWSLAADAGLLQFLQEFSQQTISRTHE 60
MMNRTTPDQELVPASEPVWERPWSVEEIRRSSQSWSLAADAGLLQFLQEFSQQTISRTHE
Sbjct: 1 MMNRTTPDQELVPASEPVWERPWSVEEIRRSSQSWSLAADAGLLQFLQEFSQQTISRTHE 60
Query: 61 IKKQVDGLIRETKATDCRLHNVFNDFLMLSNTQFIENRVYDEEVEEPVLKAEAEKTEQEK 120
IKKQVDGLIRETKATDCRLHNVFNDFLMLSNTQFIENRVYDEEVEEPVLKAEAEKTEQEK
Sbjct: 61 IKKQVDGLIRETKATDCRLHNVFNDFLMLSNTQFIENRVYDEEVEEPVLKAEAEKTEQEK 120
Query: 121 TREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYI 180
TREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYI
Sbjct: 121 TREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYI 180
Query: 181 DRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDN 240
DRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDN
Sbjct: 181 DRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDN 240
Query: 241 EQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGD 300
EQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGD
Sbjct: 241 EQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGD 300
Query: 301 AMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGL 360
AMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGL
Sbjct: 301 AMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGL 360
Query: 361 FSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFG 420
FSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFG
Sbjct: 361 FSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFG 420
Query: 421 AASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTA 480
AASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTA
Sbjct: 421 AASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTA 480
Query: 481 DIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSYSKNLKPSSETKTQKGLFSD 540
DIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSYSKNLKPSSETKTQKGLFSD
Sbjct: 481 DIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSYSKNLKPSSETKTQKGLFSD 540
Query: 541 EEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQRE 600
EEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQRE
Sbjct: 541 EEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQRE 600
Query: 601 EKAKASELSKKKASALLFSSDEEWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKT 660
EKAKASELSKKKASALLFSSDEEWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKT
Sbjct: 601 EKAKASELSKKKASALLFSSDEEWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKT 660
Query: 661 SLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVSEA 720
SLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVSEA
Sbjct: 661 SLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVSEA 720
Query: 721 PPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHSDL 780
PPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHSDL
Sbjct: 721 PPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHSDL 780
Query: 781 FSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGCDPDAHPKSTGVFQD 840
FSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGCDPDAHPKSTGVFQD
Sbjct: 781 FSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGCDPDAHPKSTGVFQD 840
Query: 841 EELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEKKR 900
EELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEKKR
Sbjct: 841 EELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEKKR 900
Query: 901 VVKKDHSVNSFKNQKHPESIQGSKEKGIWKPETPQANLAINPAALLPTAASQISEVKPVL 960
VVKKDHSVNSFKNQKHPESIQGSKEKGIWKPETPQANLAINPAALLPTAASQISEVKPVL
Sbjct: 901 VVKKDHSVNSFKNQKHPESIQGSKEKGIWKPETPQANLAINPAALLPTAASQISEVKPVL 960
Query: 961 PELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQTR 1020
PELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQTR
Sbjct: 961 PELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQTR 1020
Query: 1021 AARRLAAQESSEAEDMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAAAAPW 1080
AARRLAAQESSEAEDMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAAAAPW
Sbjct: 1021 AARRLAAQESSEAEDMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAAAAPW 1080
Query: 1081 EGGPVPGVDTSPFAKSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANPPV 1140
EGGPVPGVDTSPFAKSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANPPV
Sbjct: 1081 EGGPVPGVDTSPFAKSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANPPV 1140
Query: 1141 GGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFPLLEDEDDLFTDQKVKKNETKSSS 1200
GGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFPLLEDEDDLFTDQKVKKNETKSSS
Sbjct: 1141 GGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFPLLEDEDDLFTDQKVKKNETKSSS 1200
Query: 1201 QQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPKEKSKK 1260
QQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPKEKSKK
Sbjct: 1201 QQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPKEKSKK 1260
Query: 1261 KVEAKSIFDDDMDDIFSTGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDDPLNAFGGQ 1318
KVEAKSIFDDDMDDIFSTGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDDPLNAFGGQ
Sbjct: 1261 KVEAKSIFDDDMDDIFSTGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDDPLNAFGGQ 1318
>gi|54124343 hypothetical protein LOC387680 [Homo sapiens]
Length = 1341
Score = 2549 bits (6607), Expect = 0.0
Identities = 1301/1341 (97%), Positives = 1308/1341 (97%), Gaps = 23/1341 (1%)
Query: 1 MMNRTTPDQELVPASEPVWERPWSVEEIRRSSQSWSLAADAGLLQFLQEFSQQTISRTHE 60
MMNRTTPDQEL PASEPVWERPWSVEEIRRSSQSWSLAADAGLLQFLQEFSQQTISRTHE
Sbjct: 1 MMNRTTPDQELAPASEPVWERPWSVEEIRRSSQSWSLAADAGLLQFLQEFSQQTISRTHE 60
Query: 61 IKKQVDGLIRETKATDCRLHNVFNDFLMLSNTQFIENRVYDEEVEEPVLKAEAEKTEQEK 120
IKKQVDGLIRETKATDCRLHNVFNDFLMLSNTQFIENRVYDEEVEEPVLKAEAEKTEQEK
Sbjct: 61 IKKQVDGLIRETKATDCRLHNVFNDFLMLSNTQFIENRVYDEEVEEPVLKAEAEKTEQEK 120
Query: 121 TREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYI 180
TREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYI
Sbjct: 121 TREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYI 180
Query: 181 DRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDN 240
DRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDN
Sbjct: 181 DRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDN 240
Query: 241 EQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGD 300
EQN+HTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGD
Sbjct: 241 EQNRHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGD 300
Query: 301 AMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGL 360
A+GRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGL
Sbjct: 301 AVGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGL 360
Query: 361 FSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFG 420
FSGGKGLFDDEDEESDLFTEA QDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFG
Sbjct: 361 FSGGKGLFDDEDEESDLFTEAPQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFG 420
Query: 421 AASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTA 480
AASVPS+KEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKT KVQSTA
Sbjct: 421 AASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTA 480
Query: 481 DIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSYSKNLKPSSETKTQKGLFSD 540
DIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLS SKNLKPSSETKTQKGLFSD
Sbjct: 481 DIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSD 540
Query: 541 EEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQRE 600
EEDSEDLFSSQSAS LKGASLLPGKLPT VSLFDDEDEEDNLFGGTAAKKQTL LQAQRE
Sbjct: 541 EEDSEDLFSSQSASKLKGASLLPGKLPTLVSLFDDEDEEDNLFGGTAAKKQTLCLQAQRE 600
Query: 601 EKAKASELSKKKASALLFSSDEE--WNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVK 658
EKAKASELSKKKASALLFSSDEE WNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVK
Sbjct: 601 EKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVK 660
Query: 659 KTSLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVS 718
KTSLFEED+EDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVS
Sbjct: 661 KTSLFEEDEEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVS 720
Query: 719 EAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHS 778
EAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHS
Sbjct: 721 EAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHS 780
Query: 779 DLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGCDPDAHPKSTGVF 838
DLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKG DPDAHPKSTGVF
Sbjct: 781 DLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGRDPDAHPKSTGVF 840
Query: 839 QDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEK 898
QDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEK
Sbjct: 841 QDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEK 900
Query: 899 KRVVKKDHSVNSFKNQKHPESIQGSKEKGIWKPETP---------------------QAN 937
KRVVKKDHSV+SFKNQKHPESIQGSKEKGIWKPETP QAN
Sbjct: 901 KRVVKKDHSVDSFKNQKHPESIQGSKEKGIWKPETPQDSSGLAPFKTKEPSTRIGKIQAN 960
Query: 938 LAINPAALLPTAASQISEVKPVLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQ 997
LAINPAALLPTAASQISEVKPVLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQ
Sbjct: 961 LAINPAALLPTAASQISEVKPVLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQ 1020
Query: 998 ADTLHSANKSRVKMRGKRRPQTRAARRLAAQESSEAEDMSVPRGPIAQWADGAISPNGHR 1057
ADTLHSANKSRVKMRGKRRPQTRAARRLAAQESSE EDMSVPRGPIAQWADGAISPNGHR
Sbjct: 1021 ADTLHSANKSRVKMRGKRRPQTRAARRLAAQESSETEDMSVPRGPIAQWADGAISPNGHR 1080
Query: 1058 PQLRAASGEDSTEEALAAAAAPWEGGPVPGVDTSPFAKSLGHSRGEADLFDSGDIFSTGT 1117
PQLRAASGEDSTEEALAAAAAPWEGGPVPGVD SPFAKSLGHSRGEADLFDSGDIFSTGT
Sbjct: 1081 PQLRAASGEDSTEEALAAAAAPWEGGPVPGVDRSPFAKSLGHSRGEADLFDSGDIFSTGT 1140
Query: 1118 GSQSVERTKPKAKIAENPANPPVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFP 1177
GSQSVERTKPKAKIAENPANPPVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFP
Sbjct: 1141 GSQSVERTKPKAKIAENPANPPVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFP 1200
Query: 1178 LLEDEDDLFTDQKVKKNETKSSSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLES 1237
LLEDEDDLFTDQKVKKNETKS+SQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLES
Sbjct: 1201 LLEDEDDLFTDQKVKKNETKSNSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLES 1260
Query: 1238 NLFDDNIDIFADLTVKPKEKSKKKVEAKSIFDDDMDDIFSTGIQAKTTKPKSRSAQAAPE 1297
NLFDDNIDIFADLTVKPKEKSKKKVEAKSIFDDDMDDIFS+GIQAKTTKPKSRSAQAAPE
Sbjct: 1261 NLFDDNIDIFADLTVKPKEKSKKKVEAKSIFDDDMDDIFSSGIQAKTTKPKSRSAQAAPE 1320
Query: 1298 PRFEHKVSNIFDDPLNAFGGQ 1318
PRFEHKVSNIFDDPLNAFGGQ
Sbjct: 1321 PRFEHKVSNIFDDPLNAFGGQ 1341
>gi|154090959 hypothetical protein LOC55747 [Homo sapiens]
Length = 1253
Score = 2351 bits (6092), Expect = 0.0
Identities = 1203/1244 (96%), Positives = 1210/1244 (97%), Gaps = 23/1244 (1%)
Query: 98 RVYDEEVEEPVLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGN 157
RVYDEEVEEPVLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGN
Sbjct: 10 RVYDEEVEEPVLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGN 69
Query: 158 SDSEEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGS 217
SDSEEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGS
Sbjct: 70 SDSEEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGS 129
Query: 218 IVDTEEEKEEEESDEDFAHHSDNEQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEE 277
IVDTEEEKEEEESDEDFAHHSDNEQN+HTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEE
Sbjct: 130 IVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEE 189
Query: 278 NTRPKRSRPTSFADELAARIKGDAMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEE 337
NTRPKRSRPTSFADELAARIKGDA+GRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEE
Sbjct: 190 NTRPKRSRPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEE 249
Query: 338 DNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSS 397
DNLF PPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEA QDRQAGASVKEESSS
Sbjct: 250 DNLFTPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEAPQDRQAGASVKEESSS 309
Query: 398 SKPGKKIPAGAVSVFLGDTDVFGAASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGD 457
SKPGKKIPAGAVSVFLGDTDVFGAASVPS+KEPQKPEQPTPRKSPYGPPPTGLFDDDDGD
Sbjct: 310 SKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDGD 369
Query: 458 DDDDFFSAPHSKPSKTRKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKV 517
DDDDFFSAPHSKPSKT KVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKV
Sbjct: 370 DDDDFFSAPHSKPSKTGKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKV 429
Query: 518 TLSYSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDED 577
TLS SKNLKPSSETKTQKGLFSDEEDSEDLFSSQSAS LKGASLLPGKLPTSVSLFDDED
Sbjct: 430 TLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLPTSVSLFDDED 489
Query: 578 EEDNLFGGTAAKKQTLSLQAQREEKAKASELSKKKASALLFSSDEE--WNIPASQTHLAS 635
EEDNLFGGTAAKKQTL LQAQREEKAKASELSKKKASALLFSSDEE WNIPASQTHLAS
Sbjct: 490 EEDNLFGGTAAKKQTLCLQAQREEKAKASELSKKKASALLFSSDEEDQWNIPASQTHLAS 549
Query: 636 DSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDS 695
DSRSKGEPRDSGTLQSQEAKAVKKTSLFEED+EDDLFAIAKDSQKKTQRVSLLFEDDVDS
Sbjct: 550 DSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDEEDDLFAIAKDSQKKTQRVSLLFEDDVDS 609
Query: 696 GGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGR 755
GSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGR
Sbjct: 610 RGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGR 669
Query: 756 TDVAESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNII 815
TDVAESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNII
Sbjct: 670 TDVAESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNII 729
Query: 816 QAPQKEVGKGCDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGS 875
QAPQKEVGKG DPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGS
Sbjct: 730 QAPQKEVGKGRDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGS 789
Query: 876 LFGDDEDDDLFSSAKSQPLVQEKKRVVKKDHSVNSFKNQKHPESIQGSKEKGIWKPETP- 934
LFGDDEDDDLFSSAKSQPLVQEKKRVVKKDHSV+SFKNQKHPESIQGSKEKGIWKPETP
Sbjct: 790 LFGDDEDDDLFSSAKSQPLVQEKKRVVKKDHSVDSFKNQKHPESIQGSKEKGIWKPETPQ 849
Query: 935 --------------------QANLAINPAALLPTAASQISEVKPVLPELAFPSSEHRRSH 974
QANLAINPAALLPTAASQISEVKPVLPELAFPSSEHRRSH
Sbjct: 850 DSSGLAPFKTKEPSTRIGKIQANLAINPAALLPTAASQISEVKPVLPELAFPSSEHRRSH 909
Query: 975 GLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQTRAARRLAAQESSEAE 1034
GLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQTRAARRLAAQESSE E
Sbjct: 910 GLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQTRAARRLAAQESSETE 969
Query: 1035 DMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAAAAPWEGGPVPGVDTSPFA 1094
DMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAAAAPWEGGPVPGVD SPFA
Sbjct: 970 DMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAAAAPWEGGPVPGVDRSPFA 1029
Query: 1095 KSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANPPVGGKAKSPMFPALGE 1154
KSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANPPVGGKAKSPMFPALGE
Sbjct: 1030 KSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANPPVGGKAKSPMFPALGE 1089
Query: 1155 ASSDDDLFQSAKPKPAKKTNPFPLLEDEDDLFTDQKVKKNETKSSSQQDVILTTQDIFED 1214
ASSDDDLFQSAKPKPAKKTN FPLLEDEDDLFTDQKVKKNETKS+SQQDVILTTQDIFED
Sbjct: 1090 ASSDDDLFQSAKPKPAKKTNTFPLLEDEDDLFTDQKVKKNETKSNSQQDVILTTQDIFED 1149
Query: 1215 DIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPKEKSKKKVEAKSIFDDDMDD 1274
DIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPKEKSKKKVEAKSIFDDDMDD
Sbjct: 1150 DIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPKEKSKKKVEAKSIFDDDMDD 1209
Query: 1275 IFSTGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDDPLNAFGGQ 1318
IFS+GIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDDPLNAFGGQ
Sbjct: 1210 IFSSGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDDPLNAFGGQ 1253
>gi|169190542 PREDICTED: hypothetical protein [Homo sapiens]
Length = 308
Score = 613 bits (1582), Expect = e-175
Identities = 308/308 (100%), Positives = 308/308 (100%)
Query: 1011 MRGKRRPQTRAARRLAAQESSEAEDMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTE 1070
MRGKRRPQTRAARRLAAQESSEAEDMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTE
Sbjct: 1 MRGKRRPQTRAARRLAAQESSEAEDMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTE 60
Query: 1071 EALAAAAAPWEGGPVPGVDTSPFAKSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAK 1130
EALAAAAAPWEGGPVPGVDTSPFAKSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAK
Sbjct: 61 EALAAAAAPWEGGPVPGVDTSPFAKSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAK 120
Query: 1131 IAENPANPPVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFPLLEDEDDLFTDQK 1190
IAENPANPPVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFPLLEDEDDLFTDQK
Sbjct: 121 IAENPANPPVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFPLLEDEDDLFTDQK 180
Query: 1191 VKKNETKSSSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADL 1250
VKKNETKSSSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADL
Sbjct: 181 VKKNETKSSSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADL 240
Query: 1251 TVKPKEKSKKKVEAKSIFDDDMDDIFSTGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDD 1310
TVKPKEKSKKKVEAKSIFDDDMDDIFSTGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDD
Sbjct: 241 TVKPKEKSKKKVEAKSIFDDDMDDIFSTGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDD 300
Query: 1311 PLNAFGGQ 1318
PLNAFGGQ
Sbjct: 301 PLNAFGGQ 308
Score = 33.9 bits (76), Expect = 1.1
Identities = 46/195 (23%), Positives = 74/195 (37%), Gaps = 28/195 (14%)
Query: 724 LFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHSDLFSS 783
LF + G +SV++ AK + V K + + E DLF S
Sbjct: 96 LFDSGDIFSTGTGSQSVERTKPKAKIAENPANPPVGGKAKSPMFP-ALGEASSDDDLFQS 154
Query: 784 SSPWDKGTKPRTKT-VLSLFDEEEDKMEDQNIIQAPQKEVGKGCDPDAHPKSTGVFQD-- 840
+ P KP KT L ++E+D DQ + + E D + +F+D
Sbjct: 155 AKP-----KPAKKTNPFPLLEDEDDLFTDQKV---KKNETKSSSQQDVILTTQDIFEDDI 206
Query: 841 ---EELLFSHKLQKDN--------DPDVDLFAGT----KKTKLLEPSVGSLFGDDEDDDL 885
E + S K ++ D ++D+FA K+ + S+F DD DD+
Sbjct: 207 FATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPKEKSKKKVEAKSIFDDDM-DDI 265
Query: 886 FSSAKSQPLVQEKKR 900
FS+ + K R
Sbjct: 266 FSTGIQAKTTKPKSR 280
Score = 33.1 bits (74), Expect = 1.8
Identities = 59/265 (22%), Positives = 99/265 (37%), Gaps = 48/265 (18%)
Query: 605 ASELSKKKASALLFSSDEEWNI-PASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTSLF 663
A L + A LF S + ++ SQ+ + ++K + +AK+ +L
Sbjct: 84 AKSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANPPVGGKAKSPMFPALG 143
Query: 664 EEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVSEAPPL 723
E +DDLF AK K L ED+ D LF KK ET S +
Sbjct: 144 EASSDDDLFQSAKPKPAKKTNPFPLLEDEDD----LF------TDQKVKKNETKSSS--- 190
Query: 724 LFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHS----- 778
+++ L + + + A E++K S+K TR ++T++ +
Sbjct: 191 ------QQDVILTTQDIFEDDIFATEAIK-------PSQK----TREKEKTLESNLFDDN 233
Query: 779 -DLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGCDPDAHPKSTGV 837
D+F+ + K + S+FD++ D + I K PKS
Sbjct: 234 IDIFADLTVKPKEKSKKKVEAKSIFDDDMDDIFSTGIQAKTTK-----------PKSRSA 282
Query: 838 FQDEELLFSHKLQKDNDPDVDLFAG 862
E F HK+ D ++ F G
Sbjct: 283 QAAPEPRFEHKVSNIFDDPLNAFGG 307
>gi|169194762 PREDICTED: hypothetical protein [Homo sapiens]
Length = 86
Score = 91.3 bits (225), Expect = 6e-18
Identities = 42/43 (97%), Positives = 43/43 (100%)
Query: 1 MMNRTTPDQELVPASEPVWERPWSVEEIRRSSQSWSLAADAGL 43
MMNRTTPDQELVPASEPVWERPWSVEEIRRSSQSWSLAADAG+
Sbjct: 1 MMNRTTPDQELVPASEPVWERPWSVEEIRRSSQSWSLAADAGV 43
>gi|239753231 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
Length = 948
Score = 64.3 bits (155), Expect = 7e-10
Identities = 133/646 (20%), Positives = 241/646 (37%), Gaps = 81/646 (12%)
Query: 329 RRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGL------FDDEDEESDLFTEAS 382
RRT S +NL A + + + GK L + E+ LFT
Sbjct: 149 RRTISQQSAENLDAACGIDKTENGNMFEDQNVDKEGKALPATGQKANVSPEQPPLFTHTV 208
Query: 383 QDRQAGAS-----VKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSLKEP-QKPEQP 436
+DR ++ + +SS + ++ P +++ D PS K ++ + P
Sbjct: 209 KDRDHISTRFLGGMDSLTSSEESSERPPLSTLTLKEAD---------PSSKAAMRRKDSP 259
Query: 437 TPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKP------SKTRKVQSTADIFGDEEGDL 490
P K P DD D + + P S+ + + D ++
Sbjct: 260 PPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNI 319
Query: 491 FKEKAVASPEATVSQTDENKARA--EKKVTL--------SYSKNLKPSSETKTQKGLFSD 540
E TVS ++ + +KKV+L K+ SS+ + SD
Sbjct: 320 ATEIKKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKATSD 379
Query: 541 EEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLF--------GGTAAKKQT 592
+ DS +++ L+ ++ K P + D+ED N+ GT + ++
Sbjct: 380 KTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQ 439
Query: 593 LSLQAQREEK-------------AKASELSKKKASALLFSSDEEWNIPASQTHLASDSRS 639
+L+A +EK K+ +S +K AL +SDEE ++ S +R
Sbjct: 440 PALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSV-------LSIARE 492
Query: 640 KGEPRDSGTLQSQEAKAVKKTSLFEEDKEDDLFAIAKD---SQKKTQRVSLLFEDDVDSG 696
+ S T+ S++ A K TS E+D ++ KD S+K + + + D
Sbjct: 493 NKDGEKSRTVSSRKKPASKATS-DEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEE 551
Query: 697 GSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAK--ESLKFG 754
S+ G + K + SE PP L + +EK++ L + K E K S K
Sbjct: 552 DSVLGIAREN-KDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKP 610
Query: 755 RTDVAESEKEGL--LTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQ 812
+ EK+ +TR ++ + S P KGT +VL + E +D + +
Sbjct: 611 SLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSR 670
Query: 813 NIIQAPQKEVGKGCDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPS 872
+ + +K G D + + ++ + P K T E S
Sbjct: 671 TV--SSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPT-----LKATSDEEDS 723
Query: 873 VGSLFGDDEDDDLFSSAKSQPLVQEKKRVVKKDHSVNSFKNQKHPE 918
V S+ +++D + + S+ K +KD +N + +K+ E
Sbjct: 724 VLSIARENKDGEKSRTVSSEKPSGLKATSAEKDSVLNIARGKKYGE 769
Score = 60.5 bits (145), Expect = 1e-08
Identities = 160/821 (19%), Positives = 302/821 (36%), Gaps = 110/821 (13%)
Query: 128 DLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYIDRPLPYL 187
D++P V+EAV+ L +LD + + + + LE +++ PY
Sbjct: 106 DVLPPVEEAVDRCLYLLDRFAQPVT---------------KDKFALESENI----SEPYF 146
Query: 188 IGSKLFMEQE----DVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQN 243
+ +Q D G +E G++ D+ + ++E + + A+ S +
Sbjct: 147 TNRRTISQQSAENLDAACGIDKTENGNMFEDQ----NVDKEGKALPATGQKANVSPEQPP 202
Query: 244 QHTTQMSDEEEDD----DGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKG 299
T + D + G D SE+ E RP S T + +++
Sbjct: 203 LFTHTVKDRDHISTRFLGGMDSLTSSEESSE---------RPPLSTLTLKEADPSSKA-- 251
Query: 300 DAMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGG 359
AM R D P S + +P + + SDD++ ++ + S S
Sbjct: 252 -AMRRKDSPPPGKVSSQKQPAE--------KATSDDKDSVSNIATEIKEGPISGTVSSQK 302
Query: 360 LFSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVF 419
K D++D S++ TE + +Q+G ++ S+ K K +++
Sbjct: 303 Q-PAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGGG 361
Query: 420 GAASVPSLKEPQKPEQPTPRKSPYG---PPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKV 476
+ +V S K+P S GL A + +
Sbjct: 362 KSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNI 421
Query: 477 QSTADIFGDEEGDLFKE-----KAVASPEATVSQTDENKARAEKKVTLSYSKNLKPSSET 531
+T G++ G + + KA + +VS EK T+S + KP + T
Sbjct: 422 -ATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVS---SQKPPALT 477
Query: 532 KTQKGLFSDEEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQ 591
T SDEE S + ++ K ++ K P S + D++D N+ G
Sbjct: 478 AT-----SDEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNITRG------ 526
Query: 592 TLSLQAQREEKAKASELSKKKASALLFSSDEEWNIPASQTHLASDSRSKGEPRDSGTLQS 651
+++ + ++S +K L +SDEE ++ +R + S T+ S
Sbjct: 527 -------KKDGEISRKVSSQKPPTLKGTSDEEDSV-------LGIARENKDGEKSRTVSS 572
Query: 652 QEAKAVKKTSLFEEDKEDDLFAIAKDSQ--KKTQRVSLLFEDDVDSGG---SLFGSPPTS 706
++ +K +S D++D + IA+ + +KT+RVS + +++ F +
Sbjct: 573 EKPPGLKASS----DEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITRE 628
Query: 707 VPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAK--ESLKFGRTDVAESEKE 764
++ S+ PP L +E+++ LG+ +K E ++ S K EK+
Sbjct: 629 KKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKD 688
Query: 765 GLL--TRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEV 822
+L R ++ K + S P K T +VLS+ E +D + + + E
Sbjct: 689 SVLNIARGKKDGEKTRTVSSQKPPTLKATSDEEDSVLSIARENKDGEKSRTV----SSEK 744
Query: 823 GKGCDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDED 882
G + K + + + K ++ + T K + D E
Sbjct: 745 PSGLKATSAEKDSVLNIARGKKYGEKTKRVSSRKKPALKATSDEKDSVLYIAREKKDGEK 804
Query: 883 DDLFSSAKSQPLVQEKKRVVKKDHSVNSFKNQKHPESIQGS 923
SS K L K + K+ SV + +K E I G+
Sbjct: 805 SRTVSSQKQPAL----KAICDKEDSVPNMATEKKDEQISGT 841
Score = 46.2 bits (108), Expect = 2e-04
Identities = 107/518 (20%), Positives = 183/518 (35%), Gaps = 90/518 (17%)
Query: 196 QEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNQHT---TQMSDE 252
Q+ L + EE SV + I D E+ + + +E++ + T++ D
Sbjct: 403 QKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDG 462
Query: 253 EEDDDGCD-----LFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDAMGRVDE 307
E+ L A S++E + EN ++SR S + A++ D
Sbjct: 463 EKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSN 522
Query: 308 EPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFA------------------PPKL--- 346
GE RK +K + DEED++ PP L
Sbjct: 523 ITRGKKDGEIS-RKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKAS 581
Query: 347 TDEDFSPFGSGGG---------LFSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSS 397
+DE S G + S K + +E D F+ +++++ G ++ SS
Sbjct: 582 SDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQ 641
Query: 398 SKPGKKIPAGAVSVFLGDTDVFGAASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGD 457
P K G +D SV + K + + S PP GL D
Sbjct: 642 KPPALK----------GTSDE--EDSVLGIARENKDGEKSRTVSSEKPP--GLKATSDEK 687
Query: 458 DDDDFFSAPHSKPSKTRKVQS----TADIFGDEEGDLF---KEKAVASPEATVSQTDENK 510
D + KTR V S T DEE + +E TVS +
Sbjct: 688 DSVLNIARGKKDGEKTRTVSSQKPPTLKATSDEEDSVLSIARENKDGEKSRTVSSEKPSG 747
Query: 511 ARA---EKKVTLSYSKNLKPSSETKTQKG-------LFSDEEDSEDLFSSQSASNLKGAS 560
+A EK L+ ++ K +TK SDE+DS + + K +
Sbjct: 748 LKATSAEKDSVLNIARGKKYGEKTKRVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRT 807
Query: 561 LLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQREEKAKASELSKKKASALLFSS 620
+ K P ++ D ED N + +++++ + +S +K AL +S
Sbjct: 808 VSSQKQPALKAICDKEDSVPN-------------MATEKKDEQISGTVSSQKQPALKATS 854
Query: 621 DEEWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVK 658
D++ ++ T + + + SGT+ Q+ A K
Sbjct: 855 DKKDSVSNIPTEIK-------DGQQSGTVSPQKQSAQK 885
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 64.3 bits (155), Expect = 7e-10
Identities = 99/593 (16%), Positives = 191/593 (32%), Gaps = 17/593 (2%)
Query: 205 SSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNQHTTQMSDEEEDDDGCDLFAD 264
SS+ S S+ S D+ + + SD D + S++ + ++ SD + D D +D
Sbjct: 566 SSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSD 625
Query: 265 SEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDAMGRVDEEPTTLPSGEAKPRKTLK 324
S K E D D + + S + +D + ++ D ++ S + +
Sbjct: 626 SSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSN 685
Query: 325 EKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEASQD 384
+ +D D S S + D + S D
Sbjct: 686 SSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSD 745
Query: 385 RQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSLKEPQKPEQPTPRKSPYG 444
++ + S SS + S +D + S S + S
Sbjct: 746 SSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSD--SSNSSDSNDSSNSSDSSDSSNSSDS 803
Query: 445 PPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTADIF-------GDEEGDLFKEKAVA 497
+ D D D D S+ S S + +++D G + + +
Sbjct: 804 SNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSN 863
Query: 498 SPEATVSQTDENKARAEKKVTLSYSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASNLK 557
S +++ S N + + + S N SS++ SD DS + S +SN
Sbjct: 864 SSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSD--SDSSDSSNSSDSSDSSNSS 921
Query: 558 GASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQREEKAKASELSKKKASALL 617
+S S S D + D+ ++ S + + +S+ + +S
Sbjct: 922 DSSESSNSSDNSNS-SDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSS 980
Query: 618 FSSDEEWNIPASQTHLASDSRSKGEPRDS-----GTLQSQEAKAVKKTSLFEEDKEDDLF 672
SSD + +S + +SDS + + DS + S + + ++ + D
Sbjct: 981 NSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSS 1040
Query: 673 AIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKE 732
+ S S D DS S S + ++ E+ + SD +
Sbjct: 1041 DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSS 1100
Query: 733 AQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHSDLFSSSS 785
+S+ S +D ++S + S+ + SS S
Sbjct: 1101 DSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDS 1153
Score = 55.1 bits (131), Expect = 4e-07
Identities = 91/496 (18%), Positives = 168/496 (33%), Gaps = 32/496 (6%)
Query: 206 SEEGSVGSDRGSIVDTEEEKEEEE-SDEDFAHHSDNEQNQHTTQMSDEEEDDDGCDLFAD 264
S S SD + D+ + + + SD D ++ SD+ + ++ SD D D
Sbjct: 826 SSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDS 885
Query: 265 SEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDAMGRVDEEPTTLPSGEAKPRKTLK 324
+E N+ S +S + + D+ D ++ S + +
Sbjct: 886 NESSNSSDSSDSSNSSDSDSSDSSNSSD-----SSDSSNSSDSSESSNSSDNSNSSDSSN 940
Query: 325 EKKER-RTPSDDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEASQ 383
+ S + D+ + D S S S D + SD +
Sbjct: 941 SSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDS 1000
Query: 384 DRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSLKEPQKPEQPTPRKSPY 443
+ +S +SS S + S D+ +S S + S
Sbjct: 1001 SNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS 1060
Query: 444 GPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTADIFGDEEGDLFKEKAVASPEATV 503
D D D S+ S S + ++D + + + +S +
Sbjct: 1061 SDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1120
Query: 504 SQTDENKARAEKKVTLSYSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASNLKGASLLP 563
S + ++ ++ + S S N SS++ ++ SD DS D S +S+ +S
Sbjct: 1121 SNSSDSSDSSDSSDS-SDSSNSSDSSDS-SESSDSSDSSDSSDSSDSSDSSDSSDSS--- 1175
Query: 564 GKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQREEKAKASELSKKKASALLFSSDEE 623
S + D D D+ ++ S + + + +S+ S SSD
Sbjct: 1176 ----DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD--------SSDSS 1223
Query: 624 WNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDKEDDLFAIAKDSQKKTQ 683
+ +S ++ +SDS + DS S ++ +S D D+ DSQ K+
Sbjct: 1224 DSSDSSDSNESSDSSDSSDSSDSS--NSSDSSDSSDSSDSTSDSNDE-----SDSQSKSG 1276
Query: 684 RVSLLFED-DVDSGGS 698
+ D D DS GS
Sbjct: 1277 NGNNNGSDSDSDSEGS 1292
Score = 53.5 bits (127), Expect = 1e-06
Identities = 104/639 (16%), Positives = 209/639 (32%), Gaps = 44/639 (6%)
Query: 157 NSDSEEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRG 216
NSD +D+ NG SK + + + ++ + + + G
Sbjct: 494 NSDESKDNGNGS--------------------DSKGAEDDDSDSTSDTNNSDSNGNGNNG 533
Query: 217 SIVDTEEEKEEEESDEDFAHHSDNEQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIE 276
+ + + + + +SD + SD+ + ++ SD + D +DS+ + D D
Sbjct: 534 NDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSS--SDSDSSDSDSSDSS 591
Query: 277 ENTRPKRSRPTSFADELAARIKGDAMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDE 336
++ S + +D + D+ D + + S E+ + + + S D
Sbjct: 592 DSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKS-ESDSSDSDSKSDSSDSNSSDS 650
Query: 337 EDNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESS 396
DN + + S S S D SD + + +S +SS
Sbjct: 651 SDNSDSSDSSNSSNSS--DSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSS 708
Query: 397 SSKPGKKIPAGAVSVFLGDTDVFGAASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDG 456
S + + D+ +S S + S D
Sbjct: 709 DSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSS 768
Query: 457 DDDDDFFSAPHSKPSKTRKVQSTADIFGDEEGDLFKEKAVASPEATVSQTD-ENKARAEK 515
D D S+ S S + +++D + +S + S +D N + +
Sbjct: 769 DSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSN 828
Query: 516 KVTLSYSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDD 575
S S N SS++ SD DS+ S S+++ + + S D
Sbjct: 829 SSDSSDSSNSSDSSDSSDS----SDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSD 884
Query: 576 EDEEDNLFGGTAAKKQTLSLQAQREEKAKASELSKKKASALLFSSDEEWNIPASQTHLAS 635
+E N + + + S + + +S+ S SSD + +S +S
Sbjct: 885 SNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSN--------SSDSSESSNSSDNSNSS 936
Query: 636 DSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDKEDDLFAIAKDSQKKTQRV----SLLFED 691
DS + + DS + + S D D + + DS + S D
Sbjct: 937 DSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSD 996
Query: 692 DVDSGGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKESL 751
DS S S + ++ ++ + + SD + +S+ S
Sbjct: 997 SSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSN 1056
Query: 752 KFGRTDVAES--EKEGLLTRSAQETVKHSDLFSSSSPWD 788
+D ++S + + + ++ + SD SS+ D
Sbjct: 1057 SSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSD 1095
Score = 47.0 bits (110), Expect = 1e-04
Identities = 96/508 (18%), Positives = 175/508 (34%), Gaps = 57/508 (11%)
Query: 195 EQEDVGLGELSSEEGSVGSDRGSIVDTEEEKE---EEESDEDFAHHSDNEQNQHTTQMSD 251
E ED G G+ EE G D + +E ++ E++ D +SD+++ D
Sbjct: 253 EDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSDSKEYYDPEGKED 312
Query: 252 EEEDDDGCDLFADSEK------EEEDIEDIEENTRPKRSRPTSFADELAARIKGDAMGRV 305
+ DG D + SE+ E+ + IE+ + + + + A+G+
Sbjct: 313 PHNEVDG-DKTSKSEENSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKESETHAVGKS 371
Query: 306 DEEPTTLPSGEAKPRKTLKEKKERRTPSDD-----------------EEDNLFAPPKLTD 348
++ + + R KE + +D E N+ P + ++
Sbjct: 372 QDKGIEIKGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGEVVNIEGPGQKSE 431
Query: 349 EDFSPFGSGGGLFSGGKGL----FDDEDEESDLFTEASQDRQAG---ASVKEESSSSKPG 401
S G S G FDD+ + D S D G A+ + +++SS G
Sbjct: 432 PGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGD--DPNSSDESNGNDDANSESDNNSSSRG 489
Query: 402 KKIPAGAVSVFLGDTDVFGAASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDD 461
S G+ G+ S + + T G G +DD D D
Sbjct: 490 DASYNSDESKDNGN----GSDSKGAEDDDSDSTSDTNNSDSNGNGNNG---NDDNDKSDS 542
Query: 462 FFSAPHSKPSKTRKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSY 521
S S + +++D + D + +S ++ S +D + + S
Sbjct: 543 GKGKSDSSDSDSSDSSNSSD--SSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSN 600
Query: 522 SKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDN 581
S + SS++ SD DS D S+S S+ + + S + D DN
Sbjct: 601 SSDSSDSSDS-------SDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDN 653
Query: 582 LFGGTAAKKQTLSLQAQREEKAKASELSKKKASALLFSSDEEWNIPASQTHLASDSRSKG 641
++ S + + + +S S SSD + +S + +SDS
Sbjct: 654 SDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSN-----SSDSSDSSDSSNSSESSDSSDSS 708
Query: 642 EPRDSGTLQSQEAKAVKKTSLFEEDKED 669
+ S + S + + S D D
Sbjct: 709 DSDSSDSSDSSNSNSSDSDSSNSSDSSD 736
Score = 40.8 bits (94), Expect = 0.009
Identities = 58/356 (16%), Positives = 120/356 (33%), Gaps = 13/356 (3%)
Query: 205 SSEEGSVGSDRGSIVDTEEEKEEEES-DEDFAHHSDNEQNQHTTQMSDEEEDDDGCDLFA 263
+S + S SD + D+ + S D ++ SD+ + +++ SD + D D +
Sbjct: 940 NSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDS-S 998
Query: 264 DSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDAMGRVDEEPTTLPSGEAKPRKTL 323
DS + + + + S ++ +D + D+ D ++ S ++
Sbjct: 999 DSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSS-DSSDSSDSSNS 1057
Query: 324 KEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEASQ 383
+ + SD + + + + E S S D + SD +
Sbjct: 1058 SDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1117
Query: 384 DRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSLKEPQKPEQPTPRKSPY 443
+ +S +SS S + S ++ +S S + S
Sbjct: 1118 SDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDS 1177
Query: 444 GPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTADIFGDEEGDLFKEKAVASPEATV 503
+ D D D S+ S S + ++D + + + +S +
Sbjct: 1178 S-------NSSDSSDSSD--SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1228
Query: 504 SQTDENKARAEKKVTLSYSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASNLKGA 559
S ++E+ ++ + S S N SS++ SD D D S N G+
Sbjct: 1229 SDSNESSDSSDSSDS-SDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGS 1283
Score = 32.3 bits (72), Expect = 3.1
Identities = 30/173 (17%), Positives = 62/173 (35%), Gaps = 17/173 (9%)
Query: 206 SEEGSVGSDRGSIVDTEEEKEEEESDE--DFAHHSDNEQNQHTTQMSDEEEDDDGCDLFA 263
S S SD D+ + + +S + D + SD+ + +++ SD + D D +
Sbjct: 1138 SSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD--S 1195
Query: 264 DSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDAMGRVDEEPTTLPSGEAKPRKTL 323
+ D D +++ S +S + + + + + + S +
Sbjct: 1196 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDS 1255
Query: 324 KEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESD 376
+ + + S+DE D S SG G +G D E +S+
Sbjct: 1256 SDSSDSTSDSNDESD-------------SQSKSGNGNNNGSDSDSDSEGSDSN 1295
>gi|217330641 IWS1 homolog [Homo sapiens]
Length = 819
Score = 62.8 bits (151), Expect = 2e-09
Identities = 100/393 (25%), Positives = 146/393 (37%), Gaps = 108/393 (27%)
Query: 95 IENRVYDEEVEEPVLK--AEAEKTEQEKTR-EQKEVDLIPKVQEAVNYGL-----QVLDS 146
++ ++ D E EEP +++E E K R E + +PK Q + + Q DS
Sbjct: 178 LKPQISDSESEEPPRHQASDSENEEPPKPRMSDSESEELPKPQVSDSESEEPPRHQASDS 237
Query: 147 AFEQLDIKAGNSDSEEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSS 206
E+L K SDSE +D E ++L P P + S E ED + S
Sbjct: 238 ENEELP-KPRISDSESEDPPRHQASDSENEEL----PKPRISDS----ESEDPPRNQASD 288
Query: 207 EEG------------SVGSDRGSIVDTEEE-----KEEEESDEDFA-------------- 235
E S G +G D+E E K++ ESD+D
Sbjct: 289 SENEELPKPRVSDSESEGPQKGPASDSETEDASRHKQKPESDDDSDRENKGEDTEMQNDS 348
Query: 236 ------------HHSDNEQNQHTTQMSDEEEDDDGCDLFADSEKEEE-----------DI 272
H SD+E+ +H Q D +ED + E EEE D
Sbjct: 349 FHSDSHMDRKKFHSSDSEEEEHKKQKMDSDED--------EKEGEEEKVAKRKAAVLSDS 400
Query: 273 EDIEENTRPKRSRPTSFADELAARIKGDAMGRVDEEPTTLPSGEAKPRKTLKEKKERR-- 330
ED EE K+SR S AD+ + D G+ E T E + K L +KK
Sbjct: 401 ED-EEKASAKKSRVVSDADDSDSDAVSDKSGK--REKTIASDSEEEAGKELSDKKNEEKD 457
Query: 331 -----TPSDDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEASQDR 385
+ S +EE+NL A FG G D+E+EE F + +
Sbjct: 458 LFGSDSESGNEEENLIA---------DIFGESG----------DEEEEEFTGFNQEDLEE 498
Query: 386 QAGASVKEESSSSKPGKKIPAGAVSVFLGDTDV 418
+ G + +E+ S I G FL D ++
Sbjct: 499 EKGETQVKEAEDSDSDDNIKRGKHMDFLSDFEM 531
Score = 60.8 bits (146), Expect = 8e-09
Identities = 127/577 (22%), Positives = 204/577 (35%), Gaps = 112/577 (19%)
Query: 189 GSKLFMEQEDVGL-GELSSEEGSVGSDRGSIV-DTEEEKEEEESDEDFAHH--------- 237
G+ ++ D G GE E GSD GS+ +E E + E HH
Sbjct: 15 GATPVQDERDSGSDGEDDVNEQHSGSDTGSVERHSENETSDREDGLPKGHHVTDSENDEP 74
Query: 238 -----SDNEQNQ-HTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFAD 291
SD+E + H + SD E ++ +DSE E+ + + + R P S
Sbjct: 75 LNLNASDSESEELHRQKDSDSESEERAEPPASDSENEDVNQHGSDSESEETRKLPGS-DS 133
Query: 292 ELAARIKGDAMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDF 351
E + G A +E+ P+ +++ + +++P+ D E P+++D +
Sbjct: 134 ENEELLNGHASDSENEDVGKHPASDSEIEEL------QKSPASDSETEDALKPQISDSES 187
Query: 352 SPFGSGGGLFSGGK-----GLFDDEDEE------SDLFTEASQDRQAGASVKEE------ 394
S + + D E EE SD +E QA S EE
Sbjct: 188 EEPPRHQASDSENEEPPKPRMSDSESEELPKPQVSDSESEEPPRHQASDSENEELPKPRI 247
Query: 395 -----------SSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSLKEPQKP-----EQPTP 438
+S +++P +S + AS +E KP E P
Sbjct: 248 SDSESEDPPRHQASDSENEELPKPRISDSESEDPPRNQASDSENEELPKPRVSDSESEGP 307
Query: 439 RKSPYGPPPT--------GLFDDDDGD----------DDDDFFSAPH------------S 468
+K P T DDD D +D F S H
Sbjct: 308 QKGPASDSETEDASRHKQKPESDDDSDRENKGEDTEMQNDSFHSDSHMDRKKFHSSDSEE 367
Query: 469 KPSKTRKVQSTADIFGDEEGDLFK------------EKAVASPEATVSQTDENKARAEKK 516
+ K +K+ S D EE + K EKA A VS D++ + A
Sbjct: 368 EEHKKQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDEEKASAKKSRVVSDADDSDSDAVSD 427
Query: 517 VTLSYSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDE 576
+ K + SE + K L + + +DLF S S S + +L+ S D+E
Sbjct: 428 KSGKREKTIASDSEEEAGKELSDKKNEEKDLFGSDSESGNEEENLIADIFGES---GDEE 484
Query: 577 DEEDNLFGGTAAKKQTLSLQAQREEKAKASELSKKKASALLFSSDEEWNIPASQTHLASD 636
+EE F +++ Q + E + + + + K+ + F SD E + + S
Sbjct: 485 EEEFTGFNQEDLEEEKGETQVKEAEDSDSDD-NIKRGKHMDFLSDFEMMLQRKK----SM 539
Query: 637 SRSKGEPRDSGTLQSQ-----EAKAVKKTSLFEEDKE 668
S + RD GT S A VK EED++
Sbjct: 540 SGKRRRNRDGGTFISDADDVVSAMIVKMNEAAEEDRQ 576
Score = 53.5 bits (127), Expect = 1e-06
Identities = 112/520 (21%), Positives = 197/520 (37%), Gaps = 71/520 (13%)
Query: 202 GELSSEEGS--VGSDRGSIVDTEEEKEEEESDEDFA---HHSDNEQNQHTTQMSD----- 251
G+ S + G+ V +R S D E++ E+ S D HS+NE + +
Sbjct: 8 GDQSDDGGATPVQDERDSGSDGEDDVNEQHSGSDTGSVERHSENETSDREDGLPKGHHVT 67
Query: 252 EEEDDDGCDLFA-DSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDAMGRVDEEPT 310
+ E+D+ +L A DSE EE + ++ +R+ P + +D + EE
Sbjct: 68 DSENDEPLNLNASDSESEELHRQKDSDSESEERAEPPA-SDSENEDVNQHGSDSESEETR 126
Query: 311 TLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDD 370
LP +++ + L SD E +++ P +D + S +
Sbjct: 127 KLPGSDSENEELLNGHA-----SDSENEDVGKHPA-SDSEIEELQKSPASDSETEDALKP 180
Query: 371 EDEESDLFTEASQDRQAGASVKEESS----SSKPGKKIPAGAVSVFLGDTDVFGAASVPS 426
+ +S+ +E QA S EE S +++P VS + AS
Sbjct: 181 QISDSE--SEEPPRHQASDSENEEPPKPRMSDSESEELPKPQVSDSESEEPPRHQAS--- 235
Query: 427 LKEPQKPEQPTPR--KSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTADIFG 484
+ + E P PR S PP D + ++ P + S + +
Sbjct: 236 --DSENEELPKPRISDSESEDPPRHQASDSENEE------LPKPRISDSESEDPPRNQAS 287
Query: 485 DEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSYSKNLKPSSETKTQKGLFSDEEDS 544
D E + + V+ E+ Q + A + S K S + ++ D E
Sbjct: 288 DSENEELPKPRVSDSESEGPQ--KGPASDSETEDASRHKQKPESDDDSDRENKGEDTEMQ 345
Query: 545 EDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQREEKAK 604
D F S S + K K +S D E+EE KKQ + + +EK
Sbjct: 346 NDSFHSDSHMDRK-------KFHSS----DSEEEEH--------KKQ--KMDSDEDEKEG 384
Query: 605 ASELSKKKASALLFSSDEEWNIPASQTHLASDS--------RSKGEPRDSGTLQSQEAKA 656
E K+ +A+L S++E A ++ + SD+ K R+ E +A
Sbjct: 385 EEEKVAKRKAAVLSDSEDEEKASAKKSRVVSDADDSDSDAVSDKSGKREKTIASDSEEEA 444
Query: 657 VKKTSLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSG 696
K+ S ++++E DLF DS+ + +L+ + +SG
Sbjct: 445 GKELS-DKKNEEKDLF--GSDSESGNEEENLIADIFGESG 481
Score = 41.6 bits (96), Expect = 0.005
Identities = 116/557 (20%), Positives = 199/557 (35%), Gaps = 71/557 (12%)
Query: 352 SPFGSGGGLFSGGKGLFDDE-----DEESDLFTEASQDRQAGASVKEESSSSKPGKKIPA 406
S + SG GG DE D E D+ + S E+ +S +P
Sbjct: 3 SEYYSGDQSDDGGATPVQDERDSGSDGEDDVNEQHSGSDTGSVERHSENETSDREDGLPK 62
Query: 407 GA-VSVFLGDTDVFGAASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSA 465
G V+ D + AS +E + + PP D +++D
Sbjct: 63 GHHVTDSENDEPLNLNASDSESEELHRQKDSDSESEERAEPPAS-----DSENEDVNQHG 117
Query: 466 PHSKPSKTRKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSYSKNL 525
S+ +TRK+ + E +L A S V + + + E+
Sbjct: 118 SDSESEETRKLPGS----DSENEELLNGHASDSENEDVGKHPASDSEIEEL-------QK 166
Query: 526 KPSSETKTQKGLFSDEEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGG 585
P+S+++T+ L DSE + AS + P + D E EE
Sbjct: 167 SPASDSETEDALKPQISDSESEEPPRHQ-----ASDSENEEPPKPRMSDSESEE------ 215
Query: 586 TAAKKQTLSLQAQREEKAKASELSKKKASALLFSSDEEWNIPASQTHLA----------S 635
K Q +++ + +AS+ ++ S E + P Q + S
Sbjct: 216 -LPKPQVSDSESEEPPRHQASDSENEELPKPRISDSESEDPPRHQASDSENEELPKPRIS 274
Query: 636 DSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDKEDDLFAIAKDSQKK-TQRVSLLFEDDVD 694
DS S+ PR+ + E + + K + + + E A DS+ + R E D D
Sbjct: 275 DSESEDPPRNQAS--DSENEELPKPRVSDSESEGPQKGPASDSETEDASRHKQKPESDDD 332
Query: 695 SGGSLFGSPPT-------SVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESA 747
S G S +KK S+ S+EEE + Q D+K
Sbjct: 333 SDRENKGEDTEMQNDSFHSDSHMDRKKFHSSD------SEEEEHKKQKMDSDEDEKEGEE 386
Query: 748 KESLKFGRTDVAESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEED 807
++ K +++SE E + V +D S + DK K R KT+ S D EE+
Sbjct: 387 EKVAKRKAAVLSDSEDEEKASAKKSRVVSDADDSDSDAVSDKSGK-REKTIAS--DSEEE 443
Query: 808 KMEDQNIIQAPQKEVGKGCDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTK 867
++ + + +K++ G D ++ +EE L + + D + + F G +
Sbjct: 444 AGKELSDKKNEEKDL-FGSDSESG-------NEEENLIADIFGESGDEEEEEFTGFNQED 495
Query: 868 LLEPSVGSLFGDDEDDD 884
L E + + ED D
Sbjct: 496 LEEEKGETQVKEAEDSD 512
Score = 32.7 bits (73), Expect = 2.4
Identities = 96/458 (20%), Positives = 167/458 (36%), Gaps = 88/458 (19%)
Query: 839 QDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEK 898
++EELL H +N+ A + + L+ S S D E +D S +E
Sbjct: 134 ENEELLNGHASDSENEDVGKHPASDSEIEELQKSPAS---DSETEDALKPQISDSESEEP 190
Query: 899 KRVVKKDHSVNSFKNQKHPESIQGSKEKGIWKPETPQANLAINPAALLPTAASQISEVKP 958
R H + +N++ P+ E E P+ ++ + + P + SE +
Sbjct: 191 PR-----HQASDSENEEPPKPRMSDSES----EELPKPQVSDSESEEPPRHQASDSENEE 241
Query: 959 VLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQ 1018
LP+ SE E P S P +D+ + P+
Sbjct: 242 -LPKPRISDSES------EDPPRHQASDSENEELPKPRISDS-----------ESEDPPR 283
Query: 1019 TRAARRLAAQESSEAEDMSVPR-------GPIAQWADGAISPNGHRPQLRAASGEDSTEE 1071
+A+ SE E++ PR GP A + + + R + + S +DS E
Sbjct: 284 NQAS-------DSENEELPKPRVSDSESEGPQKGPASDSETEDASRHKQKPESDDDSDRE 336
Query: 1072 ALAAAAAPWEGGPVPGVDTSPFAKSLGHSRGEADL--FDSGDIFSTGTGSQSVERTKPKA 1129
G DT S HS D F S D S+ E K K
Sbjct: 337 N-------------KGEDTEMQNDSF-HSDSHMDRKKFHSSD-------SEEEEHKKQKM 375
Query: 1130 KIAENPANPPVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFPLLEDED-DLFTD 1188
E+ G + K A + S+D+ + AKK+ +D D D +D
Sbjct: 376 DSDEDEKE---GEEEKVAKRKAAVLSDSEDE-----EKASAKKSRVVSDADDSDSDAVSD 427
Query: 1189 QKVKKNETKSSSQQDVI---LTTQDIFEDDIFATEAIKPSQKTREKEKTLESNLF----D 1241
+ K+ +T +S ++ L+ + E D+F +++ ++ +E+ L +++F D
Sbjct: 428 KSGKREKTIASDSEEEAGKELSDKKNEEKDLFGSDS-----ESGNEEENLIADIFGESGD 482
Query: 1242 DNIDIFADLTVKPKEKSKKKVEAKSIFDDDMDDIFSTG 1279
+ + F + E+ K + + K D D DD G
Sbjct: 483 EEEEEFTGFNQEDLEEEKGETQVKEAEDSDSDDNIKRG 520
>gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
Length = 1524
Score = 61.6 bits (148), Expect = 5e-09
Identities = 116/542 (21%), Positives = 204/542 (37%), Gaps = 74/542 (13%)
Query: 329 RRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGL------FDDEDEESDLFTEAS 382
RRT S +NL A + + + GK L + E+ LFT
Sbjct: 149 RRTISQQSAENLDAACGIDKTENGNMFEDQNVDKEGKALPATGQKANVSPEQPPLFTHTV 208
Query: 383 QDRQAGAS-----VKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSLKEP-QKPEQP 436
+DR ++ + +SS + ++ P +++ D PS K ++ + P
Sbjct: 209 KDRDHISTRFLGGMDSLTSSEESSERPPLSTLTLKEAD---------PSSKAAMRRKDSP 259
Query: 437 TPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKP------SKTRKVQSTADIFGDEEGDL 490
P K P DD D + + P S+ + + D ++
Sbjct: 260 PPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNI 319
Query: 491 FKEKAVASPEATVSQTDEN--KARAEKKVTL--------SYSKNLKPSSETKTQKGLFSD 540
E TVS ++ K +KKV+L K+ SS+ + SD
Sbjct: 320 ATEIKKGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKATSD 379
Query: 541 EEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLF--------GGTAAKKQT 592
+ DS +++ L+ ++ K P + D+ED N+ GT + ++
Sbjct: 380 KTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQ 439
Query: 593 LSLQAQREEK-------------AKASELSKKKASALLFSSDEEWNIPASQTHLASDSRS 639
+L+A +EK K+ +S +K AL +SDEE ++ S +R
Sbjct: 440 PALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSV-------LSIARE 492
Query: 640 KGEPRDSGTLQSQEAKAVKKTSLFEEDKEDDLFAIAKD---SQKKTQRVSLLFEDDVDSG 696
+ S T+ S++ A+K TS E+D ++ KD S+K + + + D
Sbjct: 493 NKDGEKSRTVSSRKKPALKATS-DEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEE 551
Query: 697 GSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAK--ESLKFG 754
S+ G + K + SE PP L + EK++ L + K E K S K
Sbjct: 552 DSVLGIAREN-KDGEKSRTVSSEKPPGLKASSAEKDSVLNIARGKKDGEKTKRVSSRKKP 610
Query: 755 RTDVAESEKEGL--LTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQ 812
+ EK+ +TR ++ + S P KGT +VL + E +D + +
Sbjct: 611 SLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSR 670
Query: 813 NI 814
+
Sbjct: 671 TV 672
Score = 58.2 bits (139), Expect = 5e-08
Identities = 162/820 (19%), Positives = 304/820 (37%), Gaps = 142/820 (17%)
Query: 128 DLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYIDRPLPYL 187
D++P V+EAV+ L +LD + + + + LE +++ PY
Sbjct: 106 DVLPPVEEAVDRCLYLLDRFAQPVT---------------KDKFALESENI----SEPYF 146
Query: 188 IGSKLFMEQE----DVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQN 243
+ +Q D G +E G++ D+ + ++E + + A+ S +
Sbjct: 147 TNRRTISQQSAENLDAACGIDKTENGNMFEDQ----NVDKEGKALPATGQKANVSPEQPP 202
Query: 244 QHTTQMSDEEEDD----DGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKG 299
T + D + G D SE+ E RP S T + +++
Sbjct: 203 LFTHTVKDRDHISTRFLGGMDSLTSSEESSE---------RPPLSTLTLKEADPSSKA-- 251
Query: 300 DAMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGG 359
AM R D P S + +P + + SDD++ ++ + S S
Sbjct: 252 -AMRRKDSPPPGKVSSQKQPAE--------KATSDDKDSVSNIATEIKEGPISGTVSSQK 302
Query: 360 LFSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVF 419
K D++D S++ TE + +Q+G ++ S+ K I VS+ T +
Sbjct: 303 Q-PAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSA---WKVIFKKKVSLLNIATRIM 358
Query: 420 GAASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQST 479
G ++ ++P D D + ++ +
Sbjct: 359 GGGKSGTVSSQKQPASKA-----------------TSDKTDSALNI----ATEIKDGLQC 397
Query: 480 ADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSYSKNLKPSSETKTQKGLFS 539
+ ++ L KA E +VS EK T+S K +P+ + T
Sbjct: 398 GTVSSQKQPAL---KATTDEEDSVSNIATEIKDGEKSGTVSSQK--QPALKATT------ 446
Query: 540 DEEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQR 599
DE+DS +++ K ++ K P + D+E LS+ +
Sbjct: 447 DEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEG-------------SVLSIAREN 493
Query: 600 EEKAKASELSKKKASALLFSSDEEWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKK 659
++ K+ +S +K AL +SDE + ++ +R K + S + SQ+ +K
Sbjct: 494 KDGEKSRTVSSRKKPALKATSDE-------KDSFSNITRGKKDGEISRKVSSQKPPTLKG 546
Query: 660 TSLFEEDKEDDLFAIAKDSQ--KKTQRVSLLFEDDVDSGGSLFGSPPTSV-------PPA 710
TS D+ED + IA++++ +K++ VS + G + SV
Sbjct: 547 TS----DEEDSVLGIARENKDGEKSRTVS----SEKPPGLKASSAEKDSVLNIARGKKDG 598
Query: 711 TKKKETVSEAPPLLFSDEEEKEAQLGVK------SVDKKVESAKESLKFGRTDVAESEKE 764
K K S P L + +EK++ + + +KV S K G +D E +
Sbjct: 599 EKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSD--EEDSV 656
Query: 765 GLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGK 824
+ R ++ K + S P K T +VL++ ++D + + + Q +
Sbjct: 657 LGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSPKQPALKA 716
Query: 825 GCD-PDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDD 883
CD D+ P +DE++ + QK K T + SV ++ + +D
Sbjct: 717 ICDKEDSVPNMATEKKDEQISGTVSCQKQ--------PALKATSDKKDSVSNIPTEIKDG 768
Query: 884 DLFSSAKSQPLVQEKKRVVKKDHSVNSFKNQKHPESIQGS 923
+ SQ K VKKD SV++ + I+G+
Sbjct: 769 QQSGTVSSQKQPAWKATSVKKD-SVSNIATEIKDGQIRGT 807
>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
Length = 2663
Score = 61.2 bits (147), Expect = 6e-09
Identities = 174/837 (20%), Positives = 305/837 (36%), Gaps = 168/837 (20%)
Query: 207 EEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNQHTTQMSDEEEDDDGCDL----- 261
E G DR +++ +E+ + + + AH + ++ + D+ + D G L
Sbjct: 943 ESAEAGRDRKDALESCKERRDGRAKPEEAHREELKECGCESGFKDKSDGDFGKGLEPWER 1002
Query: 262 -FADSEKEEEDIEDIE--ENTRPKRSRPTSFADELAARIKGDAMGRVDEEPTTLPSGEAK 318
EKE++D D E E T+P+R + S + + + + + E K
Sbjct: 1003 HHPAREKEKKDGPDKERKEKTKPERYKEKSSDKDKSEKSILEKCQKDKEFDKCF-----K 1057
Query: 319 PRKTLKEK--------KERRTPSDD-EEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFD 369
+K KEK KER+ D +E A P + EDFS D
Sbjct: 1058 EKKDTKEKHKDTHGKDKERKASLDQGKEKKEKAFPGIISEDFSEKKD------------D 1105
Query: 370 DEDEE-----SDLFTEASQDRQ---AGASVKEESSSSKP---GKKIPAGAVSVFLGDTDV 418
+ +E +D+FT+ S+D + G+ K +S P G + + D
Sbjct: 1106 KKGKEKSWYIADIFTDESEDDRDSCMGSGFKMGEASDLPRTDGLQEKEEGREAYASDRH- 1164
Query: 419 FGAASVPSLKEPQKPEQPTPRKSPYGPPPTG------LFDDDDGDDDDDFFSAPHSKPSK 472
+S E QK ++P R+ G G +F+ D + ++ K
Sbjct: 1165 -RKSSDKQHPERQKDKEPRDRRKDRGAADAGRDKKEKVFEKHKEKKDKE-----STEKYK 1218
Query: 473 TRKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSYSKNLKPSSETK 532
RK +++ D D++ K+K E + D+ K++ ++K +SK K S
Sbjct: 1219 DRKDRASVDSTQDKKN---KQKLPEKAEKKHAAEDKAKSKHKEKSDKEHSKERKSSRSAD 1275
Query: 533 TQKGLFSD---------EEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLF 583
+K L EDS D S S+ + PG F + +D
Sbjct: 1276 AEKSLLEKLEEEALHEYREDSNDKISEVSSDSFTDRGQEPGLTAFLEVSFTEPPGDDK-- 1333
Query: 584 GGTAAKKQTLSLQAQREEKAKASELSKKKASALLFSSDEEWNIPASQTHLASDSRSKGEP 643
+++ L EK K E + +S+ S D E + K E
Sbjct: 1334 -----PRESACL----PEKLKEKERHRHSSSSSKKSHDRE-----------RAKKEKAEK 1373
Query: 644 RDSGTLQSQEAKAVKKTSLFEED-KEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGS 702
++ G +E + K + +E+D E D + ++ + + ED++D LF +
Sbjct: 1374 KEKGE-DYKEGGSRKDSGQYEKDFLEADAYGVSYNMKAD-------IEDELDKTIELFST 1425
Query: 703 PPTSVPPATKKKETVSEAPPLLFSDEEEK---EAQLGVKSVDKKVESAKESLKFGRTDVA 759
KK + SE P ++E K + + + KK E +E + +
Sbjct: 1426 --------EKKDKNDSEREPSKKIEKELKPYGSSAINILKEKKKREKHREKWRDEKERHR 1477
Query: 760 ESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEED------------ 807
+ +GLL E ++H + DK + PR L D+ D
Sbjct: 1478 DRHADGLLRHHRDELLRHHRDEQKPATRDKDSPPRV-----LKDKSRDEGPRLGDAKLKE 1532
Query: 808 --------------KMEDQNIIQAPQKEVGKGCDPDAHPKSTGVFQDEELLFSHKLQKDN 853
KM + N AP K+ GK DA P+ + D +L+ + + +
Sbjct: 1533 KFKDGAEKEKGDPVKMSNGNDKVAPSKDPGK---KDARPREK-LLGDGDLMMTSFERMLS 1588
Query: 854 DPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEKKR----VVKKDHSVN 909
D+++ K+ K + L D L K++P +K+ KK ++
Sbjct: 1589 QKDLEIEERHKRHKERMKQMEKLRHRSGDPKL--KEKAKPADDGRKKGLDIPAKKPPGLD 1646
Query: 910 -SFKNQKHPESIQGSKEKGIWKPETPQANLAINPAALLPT----AASQISEVKPVLP 961
FK++K ES P P A ++PA+ + A + EV P P
Sbjct: 1647 PPFKDKKLKES----------TPIPPAAENKLHPASGADSKDWLAGPHMKEVLPASP 1693
Score = 35.4 bits (80), Expect = 0.36
Identities = 76/362 (20%), Positives = 139/362 (38%), Gaps = 74/362 (20%)
Query: 101 DEEVEEPVLKAEAEKTEQEKTREQK------EVDLIPKVQEAVNYGLQVLDSAF-EQLDI 153
++E ++ K EKT+ E+ +E+ E ++ K Q+ + D F E+ D
Sbjct: 1008 EKEKKDGPDKERKEKTKPERYKEKSSDKDKSEKSILEKCQKDKEF-----DKCFKEKKDT 1062
Query: 154 KAGNSDSEEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSS------- 206
K + D+ D + L + ++ P +I S+ F E++D G+ S
Sbjct: 1063 KEKHKDTHGKDKERKASLDQGKEKK--EKAFPGII-SEDFSEKKDDKKGKEKSWYIADIF 1119
Query: 207 -------EEGSVGS-----DRGSIVDTEEEKEEEESDEDFA--HHSDNEQNQHTTQMSDE 252
+ +GS + + T+ +E+EE E +A H + QH + D+
Sbjct: 1120 TDESEDDRDSCMGSGFKMGEASDLPRTDGLQEKEEGREAYASDRHRKSSDKQHPERQKDK 1179
Query: 253 EEDD------------DGCDLFADSEKEEEDIEDIE-----------ENTRPKRSR---- 285
E D D + + KE++D E E ++T+ K+++
Sbjct: 1180 EPRDRRKDRGAADAGRDKKEKVFEKHKEKKDKESTEKYKDRKDRASVDSTQDKKNKQKLP 1239
Query: 286 ---PTSFADELAARIKGDAMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFA 342
A E A+ K + S A K+L EK E + ED+
Sbjct: 1240 EKAEKKHAAEDKAKSKHKEKSDKEHSKERKSSRSADAEKSLLEKLEEEALHEYREDSNDK 1299
Query: 343 PPKLTDEDFSPFGSGGGLFSGGKGLF-----DDEDEESDLFTEASQDRQAGASVKEESSS 397
+++ + F+ G GL + + F DD+ ES E ++++ + SSS
Sbjct: 1300 ISEVSSDSFTDRGQEPGLTAFLEVSFTEPPGDDKPRESACLPEKLKEKERH---RHSSSS 1356
Query: 398 SK 399
SK
Sbjct: 1357 SK 1358
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 60.5 bits (145), Expect = 1e-08
Identities = 153/735 (20%), Positives = 267/735 (36%), Gaps = 80/735 (10%)
Query: 217 SIVDTEEEKEEEESDEDFAHHSDNEQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIE 276
++ T++ E + S+ + H +D Q Q D E + ++ A +E +D+ +++
Sbjct: 334 ALKSTKDSLERQRSELEDRHQADIASYQEAIQQLDAELRNTKWEMAAQL-REYQDLLNVK 392
Query: 277 ENTRPKRSRPTSFADELAARIK-GDAMGRVDEEPTTLPS--------GEAKPRKTLKEKK 327
+ + + RI G + E +PS E K + K +K
Sbjct: 393 MALDIEIAAYRKLLEGEECRIGFGPIPFSLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEK 452
Query: 328 ERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEASQDRQA 387
E + E+ +E+ G GG+ ++E E + T++ +A
Sbjct: 453 ETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGE---EEEAEGGEEETKSPPAEEA 509
Query: 388 GASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSLKEPQKPEQPTPRKSPYGPPP 447
+ KE S K K PA A S + A S +K P+K + P ++ PP
Sbjct: 510 ASPEKEAKSPVKEEAKSPAEAKS-----PEKEEAKSPAEVKSPEKAKSPAKEEAK-SPPE 563
Query: 448 TGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTADIFGDEEGDL-FKEKAVASPEATVSQT 506
+ ++ + S +K + +S A+ E+ KE+A + EA
Sbjct: 564 AKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVK 623
Query: 507 DENKARAEKKVTLSYSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASNLKGASLLPGKL 566
+E K+ AE K S K P+ E E E ++ S +K + P K
Sbjct: 624 EEAKSPAEVK---SPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKA 680
Query: 567 PTSVSLFDDEDEEDNLFGGTAAK-----KQTLSLQAQREEKAKASELSKKKASALLFSSD 621
+ V E+ AK K + +A+ EKAK+ + K +
Sbjct: 681 KSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAK-------TP 733
Query: 622 EEWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKA-VKKTSLFEEDK-EDDLFAIAKDSQ 679
E+ P + + + E + ++S EAK K+ + DK + + K+
Sbjct: 734 EKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEV 793
Query: 680 KKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKS 739
K ++ ++D + P +P KK+E S EEEK ++ VK
Sbjct: 794 KSPEKAKSPLKEDAKA-------PEKEIP---KKEEVKSPVK------EEEKPQEVKVKE 837
Query: 740 VDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVL 799
KK E K T E +K+ + ++ + P KP+ V
Sbjct: 838 PPKKAEEEKAP----ATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEP--AVEKPKESKVE 891
Query: 800 SLFDEEEDKMEDQNIIQAPQKEVGKGCD--PDAHPK-STGVFQDEELLFSHKLQKDNDPD 856
+ +E EDK + + P+KE + DA PK T V + E K ++ + P
Sbjct: 892 AKKEEAEDKKK----VPTPEKEAPAKVEVKEDAKPKEKTEVAKKEP--DDAKAKEPSKPA 945
Query: 857 VDLFAG-------TKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEKKRVVKKDHSVN 909
A +K K E + EDD S S+P ++ ++ D
Sbjct: 946 EKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQ--- 1002
Query: 910 SFKNQKHPESIQGSK 924
K+ K PE K
Sbjct: 1003 --KDSKPPEKATEDK 1015
Score = 58.5 bits (140), Expect = 4e-08
Identities = 126/619 (20%), Positives = 230/619 (37%), Gaps = 85/619 (13%)
Query: 196 QEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNQHTTQMSDEEED 255
+E + + E S +E + ++ EE EEE E +E ++
Sbjct: 441 EEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKE---------------AKEEEGKE 485
Query: 256 DDGCDLFADSEKEEEDIEDIEENTR-PKRSRPTSFADELAARIKGDAMGRVDEEPTTLPS 314
++G EEE+ E EE T+ P S E + +K +A + E +
Sbjct: 486 EEG--------GEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEA--KSPAEAKSPEK 535
Query: 315 GEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEE 374
EAK +K ++ ++P+ +E +PP+ + S + S K EE
Sbjct: 536 EEAKSPAEVKSPEKAKSPAKEEAK---SPPEAKSPEKEEAKSPAEVKSPEKAK-SPAKEE 591
Query: 375 SDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSLKEPQKPE 434
+ EA +A + VKEE+ S PA A S + A S +K P+K +
Sbjct: 592 AKSPAEAKSPEKAKSPVKEEAKS-------PAEAKSPVKEE-----AKSPAEVKSPEKAK 639
Query: 435 QPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQS--TADIFGDEEGDLFK 492
PT ++ P + ++ + S ++ K +S A+ E+
Sbjct: 640 SPT-KEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPV 698
Query: 493 EKAVASPEATVSQTDENKARAEKKVTLSYSKNLKPSSETKTQKGLFSDEEDSEDLFSSQS 552
++ SPE S E +A++ +K + K + K+ E+ S +
Sbjct: 699 KEEAKSPEKAKSPVKE-EAKSPEKAKSPVKEEAKTPEKAKSPV--------KEEAKSPEK 749
Query: 553 ASNLKGASLLPGKLPTSVSLFDDEDEED-NLFGGTAAKKQTLSLQAQREEKAKASELSKK 611
A + + A L K P + + +E + F A K + + + EKAK+
Sbjct: 750 AKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKA--KSPVKEEVKSPEKAKSPLKEDA 807
Query: 612 KASALLFSSDEEWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDKEDDL 671
KA EE P + + + K P+ + + ++A A KT E+K+D
Sbjct: 808 KAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKA---EEEKAPATPKT----EEKKDS- 859
Query: 672 FAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEK 731
K+ K + E+ + P P +K + EA E++K
Sbjct: 860 ---KKEEAPKKEAPKPKVEEKKE--------PAVEKPKESKVEAKKEEA-------EDKK 901
Query: 732 EAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHSDLF--SSSSPWDK 789
+ K KVE +++ +T+VA+ E + + + + + + +K
Sbjct: 902 KVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEK 961
Query: 790 GTKPRTKTVLSLFDEEEDK 808
KP K +E+DK
Sbjct: 962 AKKPEEKPKTEAKAKEDDK 980
Score = 42.7 bits (99), Expect = 0.002
Identities = 167/808 (20%), Positives = 287/808 (35%), Gaps = 118/808 (14%)
Query: 489 DLFKEKAVASPEATVSQTDE-NKARAEKKVTLSYSKNLKPSSETKTQKGLFSDEEDSEDL 547
D E A + +A S +E + R + + + + LK + ++ ++ ++ D+
Sbjct: 298 DRLSEAAKVNTDAMRSAQEEITEYRRQLQARTTELEALKSTKDSLERQRSELEDRHQADI 357
Query: 548 FSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQREEKAKASE 607
S Q A A L K + L + +D K L ++ K E
Sbjct: 358 ASYQEAIQQLDAELRNTKWEMAAQLREYQD--------LLNVKMALDIEIAAYRKLLEGE 409
Query: 608 LSKKKASALLFSSDEEW-NIPASQTHLASDSRSK---GEPRDSGTL----QSQEAKAVKK 659
+ + FS E IP+ TH+ S K E + T+ Q++E + ++
Sbjct: 410 ECRIGFGPIPFSLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEE 469
Query: 660 TSLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKK------ 713
+ EE+KE AK+ + K + E++ + G SPP + +K
Sbjct: 470 VTE-EEEKE------AKEEEGKEEEGGE--EEEAEGGEEETKSPPAEEAASPEKEAKSPV 520
Query: 714 KETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRS--- 770
KE ++EE ++ VKS +K AKE K + EKE + +
Sbjct: 521 KEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAK-SPPEAKSPEKEEAKSPAEVK 579
Query: 771 AQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGCDPDA 830
+ E K + SP + + + K+ + +EE K + ++P KE K
Sbjct: 580 SPEKAKSPAKEEAKSPAEAKSPEKAKSPV----KEEAKSPAE--AKSPVKEEAKSPAEVK 633
Query: 831 HPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAK 890
P+ EE + +K P+ + +K K P ++ AK
Sbjct: 634 SPEKAKSPTKEE---AKSPEKAKSPEKEEAKSPEKAK--SPVKAEAKSPEK-------AK 681
Query: 891 SQPLVQEKKRVVKKDHSVNSFKNQKHPESIQGSKEKGIWKPETPQANLAINPAALLPTAA 950
S P+ E K K V + K PE + ++ PE +A + A P A
Sbjct: 682 S-PVKAEAKSPEKAKSPVK--EEAKSPEKAKSPVKEEAKSPE--KAKSPVKEEAKTPEKA 736
Query: 951 SQISEVKPVLPELAFPSSEHRRSHGLESVPV-LPGSGEAGVSFD-LPAQADTLHSANKSR 1008
+ + PE A S E ++ ++S P EA D P +A S K
Sbjct: 737 KSPVKEEAKSPEKA-KSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAK---SPVKEE 792
Query: 1009 VKMRGKRRPQTRAARRLAAQESSEAEDMSVPRGPIAQWADGAISPNGHRPQLRAASGEDS 1068
VK K + + + +E + E++ P + + + + + A
Sbjct: 793 VKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPK 852
Query: 1069 TEEALAAAA--APWEGGPVPGVDTS--PFAKSLGHSRGEADLFDSGDIFSTGTGSQSV-- 1122
TEE + AP + P P V+ P + S+ EA ++ D T +
Sbjct: 853 TEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPA 912
Query: 1123 -----ERTKPKAKIAENPANPPVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFP 1177
E KPK K E P KAK P KPA+K P
Sbjct: 913 KVEVKEDAKPKEK-TEVAKKEPDDAKAKEPS-------------------KPAEKKEAAP 952
Query: 1178 LLEDEDDLFTDQKVKKNETKSSSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLES 1237
+D + + +K +T++ +++D D + E KP + EK + +
Sbjct: 953 EKKDTKEEKAKKPEEKPKTEAKAKED----------DKTLSKEPSKPKAEKAEKSSSTDQ 1002
Query: 1238 NLFDDNIDIFADLTVKPKEKSKKKVEAK 1265
KP EK+ + AK
Sbjct: 1003 K------------DSKPPEKATEDKAAK 1018
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 57.0 bits (136), Expect = 1e-07
Identities = 120/596 (20%), Positives = 222/596 (37%), Gaps = 103/596 (17%)
Query: 205 SSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNQHTTQMSDEEEDDDGCDLFAD 264
S E V +RG +++ +E EEE +E+ + E+ + + DEEE++
Sbjct: 1048 SPESRPVTGERGQLLELSKESSEEEEEEE----DEEEEEEEEEEEEDEEEEE-------- 1095
Query: 265 SEKEEEDIEDIEENTRPKRSRPTSFADE-----LAARIKGDAMGRVDEEPTTLPSGEAKP 319
E+EEE+ E+ +++ P+ ++P S A + + + +G R++ TT
Sbjct: 1096 -EEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTT-------- 1146
Query: 320 RKTLKEKKERRTPSDDEEDNLFAPPKL--------TDEDFSPFGSGGGLFSGGKGLFDDE 371
+T+ E E D D P+L ++ P GK +E
Sbjct: 1147 -ETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKKRQTEE 1205
Query: 372 DEESD--LFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSL-K 428
+E D F A R ++ ++SS+ K G K + V+ + L K
Sbjct: 1206 EEGKDNHCFKNADPCRN---NMNDDSSNLKEGSKDNPEPLKC----KQVWPKGTKRGLSK 1258
Query: 429 EPQKPEQPTPRK-SPYGPPPTGLFDDDDGD-DDDDFFSAPHSKPSKTRKVQSTADIFGDE 486
Q E+ T K + Y PP T + D+ ++ S + PS R
Sbjct: 1259 WRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIR------------ 1306
Query: 487 EGDLFKEKAVASPEATVSQTDENKARAEKKVTLSYSKNLKPSSE-TKTQKGLFSDEEDSE 545
+E+ + EA + Q + + V+ + S KP + K ++ +EE+ E
Sbjct: 1307 ----IEEEVKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEE 1362
Query: 546 DLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQREEKAKA 605
+ ++E+E + GG +K ++Q +E+ +
Sbjct: 1363 E---------------------------EEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEI 1395
Query: 606 SELSKKKASALLFSSDEEWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTSLFEE 665
S ++K+ SA L +EE +H ++ + DS ++ K F+E
Sbjct: 1396 S--TEKEDSARLDDHEEEEEEDEEPSH--NEDHDADDEDDSHMESAEVEKEELPRESFKE 1451
Query: 666 DKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVSEAPPLLF 725
E+ + + Q +L + VD S P E+ E PP
Sbjct: 1452 VLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVPESDEEPPP--- 1508
Query: 726 SDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHSDLF 781
++ +K+ Q K VD + + + T +SE + QE+ + D F
Sbjct: 1509 GEQAQKQDQKNSKEVDTEFKEGNPA-----TMEIDSETVQAVQSLTQESSEQDDTF 1559
Score = 45.4 bits (106), Expect = 4e-04
Identities = 52/222 (23%), Positives = 91/222 (40%), Gaps = 49/222 (22%)
Query: 194 MEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNQHTTQMSDEE 253
+E++ G EE + +++ ++ +EEEE DE+ +H+ D+ D +
Sbjct: 1378 VEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDH----------DAD 1427
Query: 254 EDDDGCDLFADSEKEEEDIEDIEE-----------NTRPKRSRPTSFAD---ELAA---- 295
++DD A+ EKEE E +E N +P S P D +L A
Sbjct: 1428 DEDDSHMESAEVEKEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNS 1487
Query: 296 ---RIKGD--AMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDED 350
+ GD A+ DEEP P GE ++ K KE ++ +E N P + D
Sbjct: 1488 EPKELAGDPEAVPESDEEP---PPGEQAQKQDQKNSKE--VDTEFKEGN----PATMEID 1538
Query: 351 FSPFGSGGGLFSGGKGLFDDEDEESDLFTEASQDRQAGASVK 392
+ L + E+ D F + ++ ++A S++
Sbjct: 1539 -------SETVQAVQSLTQESSEQDDTFQDCAETQEACRSLQ 1573
Score = 38.9 bits (89), Expect = 0.033
Identities = 106/590 (17%), Positives = 206/590 (34%), Gaps = 110/590 (18%)
Query: 96 ENRVYDEEVEEPVLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKA 155
E DEE EE + E ++ E+E+ E++E + I + V +K
Sbjct: 1072 EEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKK 1131
Query: 156 G--------NSDSEEDDANGRVELILEPKD-LYIDRPLPYLIGSKLFMEQEDVGLGELSS 206
NS + + E++ EP D +RP+P L + +ED G
Sbjct: 1132 KRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEED---GRKPV 1188
Query: 207 EEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNQHTTQMSDEEEDDD--------- 257
+ G TEEE+ ++ A N N ++ + + +D+
Sbjct: 1189 LRKAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVW 1248
Query: 258 ---------------------GCDLFADSEKEEEDIEDI----EENTRPKRSRPTSFADE 292
+L+ E E E + ++ T ++ P+ E
Sbjct: 1249 PKGTKRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIE 1308
Query: 293 LAARIKGDAMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFS 352
+ G+A+ LP E + +T +P + ED+L P + +E
Sbjct: 1309 EEVKETGEAL---------LPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEE--- 1356
Query: 353 PFGSGGGLFSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVF 412
+E+EE + E ++ + G +V+++ +K +K +S
Sbjct: 1357 -----------------EEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEK-EEPEISTE 1398
Query: 413 LGDTDVFGAASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSK 472
D+ A +E ++ E+P+ +D D DD+DD +
Sbjct: 1399 KEDS----ARLDDHEEEEEEDEEPSHN------------EDHDADDEDDSHMESAEVEKE 1442
Query: 473 TRKVQSTADIFGDEEG--DLFKEKAVASPEA--------TVSQTDENKARAEKKVTLSYS 522
+S ++ ++E DL + ++PE T S E K A + S
Sbjct: 1443 ELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVPES 1502
Query: 523 KNLKPSSETKTQKGLFSDEEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNL 582
P E + QK D+++S+++ + N + + SL + E+D+
Sbjct: 1503 DEEPPPGE-QAQK---QDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQESSEQDDT 1558
Query: 583 FGGTAAKKQTLSLQAQREEKAKASELSKKKASALLFSSDEEWNIPASQTH 632
F A ++ + + ++ S + A+ L + + P S H
Sbjct: 1559 FQDCAETQEA----CRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVH 1604
>gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens]
Length = 710
Score = 56.2 bits (134), Expect = 2e-07
Identities = 122/588 (20%), Positives = 219/588 (37%), Gaps = 116/588 (19%)
Query: 365 KGLFDDEDEESDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASV 424
K D++D S++ TE + +Q+G ++ S+ K K +++ T + G
Sbjct: 101 KATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIA---TRIMGGGKS 157
Query: 425 PSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTADIFG 484
++ ++P T T + D K + +++T D
Sbjct: 158 GTVSSQKQPASKTASDKTDSALNTAT-------EIKDGLQCGTVSSQKQQALKATTD--- 207
Query: 485 DEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSYSKNLKPSSE-TKTQKGLFSD-EE 542
EEG +VS EK T+S K KP+ + T +K FS+
Sbjct: 208 -EEG-------------SVSNIATEIKDGEKSGTVSSQK--KPALKATSDEKDSFSNITR 251
Query: 543 DSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQREEK 602
+ +D S++ S+ K +L + L +++D T + Q L+A R+EK
Sbjct: 252 EKKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEK 311
Query: 603 -------------AKASELSKKKASALLFSSDEEWNIPASQTHLASDSRSKGEPRDSGTL 649
K +S +K AL +SDE+ ++ +R K + S +
Sbjct: 312 DSLLNIARGKKNGEKTRRVSSRKKPALKATSDEK-------DSFSNITRGKKDGEISRKV 364
Query: 650 QSQEAKAVKKTSLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPP 709
SQ+ +K TS D+ED + IA++++
Sbjct: 365 SSQKPPTLKGTS----DEEDSVLGIARENKD----------------------------- 391
Query: 710 ATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAK--ESLKFGRTDVAESEKEGL- 766
K + SE PP L + +EK++ L + K E K S K + EK+
Sbjct: 392 GEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFS 451
Query: 767 -LTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKG 825
+TR ++ + S P KGT +VL + E +D + + + + +K G
Sbjct: 452 NITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTV--SSEKPPGLK 509
Query: 826 CDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDL 885
D + + +L + +KD + + KK L S D++D L
Sbjct: 510 ATSD---------EKDSVLNIARGKKDGE-KTRTVSSRKKPALKATS------DEKDSVL 553
Query: 886 F------SSAKSQPLVQEK----KRVVKKDHSVNSFKNQKHPESIQGS 923
+ KS+ + +K K + K+ SV + +K E I G+
Sbjct: 554 YIAREKKDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISGT 601
Score = 48.9 bits (115), Expect = 3e-05
Identities = 111/522 (21%), Positives = 192/522 (36%), Gaps = 91/522 (17%)
Query: 196 QEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNQHTTQMSDEEED 255
Q+ L + EEGSV + I D E+ + + +E++ + ++++
Sbjct: 197 QKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDG 256
Query: 256 DDGCD--------LFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGD------- 300
+ L A S KE+ + E ++SR SF + D
Sbjct: 257 EISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLN 316
Query: 301 -AMGRVDEEPTTLPSGEAKP--RKTLKEKKERRTPSDDEEDNLFA-------PPKL---T 347
A G+ + E T S KP + T EK + ++D + PP L +
Sbjct: 317 IARGKKNGEKTRRVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTS 376
Query: 348 DEDFSPFGSGGGLFSGGK----------GLFDDEDEESDLFTEASQDRQAGASVKEESSS 397
DE+ S G G K GL DE+ + A + ++ G K SS
Sbjct: 377 DEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIA-RGKKYGEKTKRVSSR 435
Query: 398 SKPGKKIPAGAVSVFLGDTDVFGAASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGD 457
KP + + F T +K + RK PP L D +
Sbjct: 436 KKPSLEATSDEKDSFSNITR-------------EKKDGEISRKVSSQKPPA-LKGTSDEE 481
Query: 458 DDDDFFSAPHSKPSKTRKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKV 517
D + + K+R V S ++ L KA + + +V K EK
Sbjct: 482 DSVLGIARENKDGEKSRTVSS------EKPPGL---KATSDEKDSVLNIARGKKDGEKTR 532
Query: 518 TLSYSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDED 577
T+S K KP+ + SDE+DS + + K ++ K P ++ D ED
Sbjct: 533 TVSSRK--KPALKAT------SDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKED 584
Query: 578 EEDNLFGGTAAKKQTLSLQAQREEKAKASELSKKKASALLFSSDEEWNIPASQTHLASDS 637
N + +++++ + +S +K AL +SD++ ++ T +
Sbjct: 585 SVPN-------------MATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIK--- 628
Query: 638 RSKGEPRDSGTLQSQEAKAVKKTSLFEEDKEDDLFAIAKDSQ 679
+ + SGT+ SQ+ A K TS+ ++D ++ KD Q
Sbjct: 629 ----DGQQSGTVSSQKQPAWKATSV-KKDSVSNIATEIKDGQ 665
Score = 46.6 bits (109), Expect = 2e-04
Identities = 85/420 (20%), Positives = 155/420 (36%), Gaps = 65/420 (15%)
Query: 373 EESDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSLKEPQK 432
+E D ++ ++ G + SS KP K + F T + QK
Sbjct: 309 DEKDSLLNIARGKKNGEKTRRVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQK 368
Query: 433 PEQPTPRKSPYGPPPTGLFDDDDG--------DDDDDFFSAPHSKPSKTRKVQSTAD-IF 483
P P G D++D D + + KP + D +
Sbjct: 369 P-----------PTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVL 417
Query: 484 GDEEGDLFKEKAVA-------SPEATVSQTDENKARAEKKVTLSYSKNLKPSSETKTQKG 536
G + EK S EAT + D +K S+ + S + KG
Sbjct: 418 NIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVS-SQKPPALKG 476
Query: 537 LFSDEEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQ 596
SDEEDS + ++ K ++ K P + D++D N+ G
Sbjct: 477 T-SDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARG----------- 524
Query: 597 AQREEKAKASELSKKKASALLFSSDEEWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKA 656
+++ K +S +K AL +SDE+ ++ ++A R K + S T+ SQ+ A
Sbjct: 525 --KKDGEKTRTVSSRKKPALKATSDEKDSV----LYIA---REKKDGEKSRTVSSQKQPA 575
Query: 657 VKKTSLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKET 716
+K DKED + +A ++KK +++S G++ ++ + KK++
Sbjct: 576 LKAIC----DKEDSVPNMA--TEKKDEQIS----------GTVSSQKQPALKATSDKKDS 619
Query: 717 VSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVK 776
VS P + ++ + K K+S+ T++ + + G ++ Q K
Sbjct: 620 VSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSPQKQSAQK 679
>gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH
polyclonal antibodies [Homo sapiens]
Length = 1430
Score = 55.8 bits (133), Expect = 3e-07
Identities = 147/749 (19%), Positives = 267/749 (35%), Gaps = 129/749 (17%)
Query: 105 EEPVLKAEAEK------TEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNS 158
++P LK ++K T E EQK ++P V++ +N L D+ + +
Sbjct: 24 KQPALKDTSDKNDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTEDEFAL 83
Query: 159 DSE----------EDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEE 208
+SE + + +E +L P + +DR L YL+ +D E +
Sbjct: 84 ESEIISKLYIPKRKIISPRSIEDVLPPVEEAVDRCL-YLLDRFAQAVTKDKFALESENIS 142
Query: 209 GSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNQHTTQMSDEEEDDDGCDLFADSEKE 268
++R +I EK + D + ++ T D+ D +G L A +K
Sbjct: 143 EPYFTNRRTISQQSAEKLDAACGID--------KTENGTLFEDQNVDKEGKALPATGQKA 194
Query: 269 EEDIEDIEENTRPKRSRPTSFADELAARIKGDAMGRVDEEPTTLPSGEAKPRKTLKEKKE 328
++ P + +D ++ R +G +D ++ S E P TL K+
Sbjct: 195 -----NVSPEQPPLFTHTVKDSDHISTRF----LGSMDSLTSSEESSERPPLSTLTLKEA 245
Query: 329 RRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEASQDRQAG 388
+ PP P K DD+D S++ TE + +G
Sbjct: 246 DPSSKAAMRRKDSPPPGKVSSQKQP---------AEKATSDDKDSVSNIATEIKEGPISG 296
Query: 389 ASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSLKEPQKPEQPTPRKSPYGPPPT 448
SS +P +K + D + +KE Q+ +P+K
Sbjct: 297 TV----SSQKQPAEKATS--------DEKDSVSNIATEIKEGQQSGTVSPQKQ------- 337
Query: 449 GLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDE 508
+ K + +T G + G + +K S +AT +TD
Sbjct: 338 ------------SAWKVIFKKKVSLLNI-ATRITGGGKSGTVSSQKQPPS-KATSDKTDS 383
Query: 509 NKARAEKKVTLSYSKNLKP-------SSETKTQKGLFSDEEDSEDLFSSQSASNLKGASL 561
L+ + +K SS+ + +DEEDS +++ K ++
Sbjct: 384 ---------ALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTV 434
Query: 562 LPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQREEKAKASELSKKKASALLFSSD 621
K P + D+ED L++ + ++ K+ +S +K AL ++D
Sbjct: 435 SSQKQPALKATTDEED-------------SVLNIATEIKDGEKSETVSSQKQPALKATTD 481
Query: 622 EEWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDKEDDLFAIAKDSQKK 681
EE ++ T + + SGT+ S++ A+K TS D++D I + +KK
Sbjct: 482 EEDSVSIIATEIKDGEK-------SGTVSSRKKPALKATS----DEKDSFSNITR--EKK 528
Query: 682 TQRVSLLFEDDVDSGGSLFGSPPTSV-------PPATKKKETVSEAPPLLFSDEEEKEAQ 734
+S SV K + SE PP L + +EK++
Sbjct: 529 DGEISRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLKATRDEKDSL 588
Query: 735 LGVKSVDKKVESAKESLKFGRTDV-AESEKEGLLTRSAQETVKH---SDLFSSSSPWDKG 790
L + K E + + + A S+KE + A ET + S P K
Sbjct: 589 LNIARGKKYGEKTRRVSSHKQPALKATSDKENSVPNMATETKDEQISGTVSSQKQPALKA 648
Query: 791 TKPRTKTVLSLFDEEEDKMEDQNIIQAPQ 819
T + +V ++ E +D + + Q
Sbjct: 649 TSDKKDSVSNIPTEIKDGQQSGTVSSQKQ 677
Score = 47.4 bits (111), Expect = 9e-05
Identities = 90/447 (20%), Positives = 174/447 (38%), Gaps = 44/447 (9%)
Query: 526 KPSSETKTQKGLFSDEEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGG 585
K SS+ + + SD++DS +++ ++ K P + D++D N+
Sbjct: 263 KVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 322
Query: 586 TAAKKQTLSLQAQREEKAKASELSKKKASALLFSS-----------DEEWNIPASQTHLA 634
+Q+ ++ Q++ K + KKK S L ++ + P+ T
Sbjct: 323 IKEGQQSGTVSPQKQSAWKV--IFKKKVSLLNIATRITGGGKSGTVSSQKQPPSKATSDK 380
Query: 635 SDS--RSKGEPRDS---GTLQSQEAKAVKKTSLFEEDKEDDLFAIAKDSQK------KTQ 683
+DS E +D GT+ SQ+ A+K T+ EED ++ KD +K + Q
Sbjct: 381 TDSALNIATEIKDGLQCGTVSSQKQPALKATT-DEEDSVSNIATEIKDGEKSGTVSSQKQ 439
Query: 684 RVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVSEAPPLL--FSDEEEKEAQLGVKSVD 741
D+ DS ++ T + K + S+ P L +DEE+ + + + D
Sbjct: 440 PALKATTDEEDSVLNI----ATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKD 495
Query: 742 KKVESAKESLKFGRTDVAESEKEGL--LTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVL 799
+ S K EK+ +TR ++ + S P K T +VL
Sbjct: 496 GEKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSDEEDSVL 555
Query: 800 SLFDEEEDKMEDQNIIQAPQKEVGKGCDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDL 859
S+ EE+D + + + + ++ G D + + ++ + K ++ +
Sbjct: 556 SIAREEKDGEKSRTV--SSEQPPGLKATRDEKDSLLNIARGKK--YGEKTRRVSSHKQ-- 609
Query: 860 FAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEKKRVVKKDHSVN---SFKNQKH 916
K T E SV ++ + +D+ + + SQ K KKD N K+ +
Sbjct: 610 -PALKATSDKENSVPNMATETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQ 668
Query: 917 PESIQGSKEKGIWKPETPQANLAINPA 943
++ K+ WK + + + N A
Sbjct: 669 SGTVSSQKQLA-WKATSVKKDSVSNIA 694
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 55.8 bits (133), Expect = 3e-07
Identities = 35/120 (29%), Positives = 51/120 (42%), Gaps = 6/120 (5%)
Query: 208 EGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNQHTTQMSDEEEDDDG--CDLFADS 265
EG S S EE+ EE+E DED D + + ++EE D C L+ADS
Sbjct: 964 EGEEASQESSSEKDEEDDEEDEEDEDREEAVDTTKKETEVSDGEDEESDSSSKCSLYADS 1023
Query: 266 EKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDAMGRVDEE----PTTLPSGEAKPRK 321
+ E + D E ++ S +S + ++ DEE P LPS PR+
Sbjct: 1024 DGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPPPRE 1083
Score = 43.1 bits (100), Expect = 0.002
Identities = 51/244 (20%), Positives = 103/244 (42%), Gaps = 32/244 (13%)
Query: 368 FDDEDEESDLFTEASQDRQAGASVKEESSSSKPG--------KKIPAGAVSVFLGDTDVF 419
++ ++E++ F A++ +QA KE++ +PG K + F + +
Sbjct: 827 WESKEEKAKPFQNAAK-QQAKEEDKEKTKLKEPGLLSLVDWAKSGGTTGIEAFAFGSGLR 885
Query: 420 GAASVPSLKEPQK-PEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSA----PHSKPSKTR 474
GA +PS K +K P + + P P+ ++D+ D + + + P +KP K
Sbjct: 886 GALRLPSFKVKRKEPSEISEASEEKRPRPSTPAEEDEDDPEQEKEAGEPGRPGTKPPKRD 945
Query: 475 KVQSTAD------IFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLS-----YSK 523
+ + D EG+ +++ + + + DE E+ V + S
Sbjct: 946 EERGKTQGKHRKSFALDSEGEEASQESSSEKDEEDDEEDEEDEDREEAVDTTKKETEVSD 1005
Query: 524 NLKPSSETKTQKGLFSDEE-------DSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDE 576
S++ ++ L++D + DSE SS S+S+ +S +S S +DE
Sbjct: 1006 GEDEESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDE 1065
Query: 577 DEED 580
+EE+
Sbjct: 1066 EEEE 1069
Score = 41.6 bits (96), Expect = 0.005
Identities = 60/276 (21%), Positives = 104/276 (37%), Gaps = 41/276 (14%)
Query: 314 SGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGL--FSGGKGL---- 367
S E K + K++ D E+ L P L+ D++ G G+ F+ G GL
Sbjct: 829 SKEEKAKPFQNAAKQQAKEEDKEKTKLKEPGLLSLVDWAKSGGTTGIEAFAFGSGLRGAL 888
Query: 368 ----FDDEDEESDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAAS 423
F + +E +EAS++++ S E P ++ AG
Sbjct: 889 RLPSFKVKRKEPSEISEASEEKRPRPSTPAEEDEDDPEQEKEAGE-------------PG 935
Query: 424 VPSLKEPQKPE-----QPTPRKS-------PYGPPPTGLFDDDDGDDDDDFFSAPHSKPS 471
P K P++ E Q RKS + D++ D++D+
Sbjct: 936 RPGTKPPKRDEERGKTQGKHRKSFALDSEGEEASQESSSEKDEEDDEEDEEDEDREEAVD 995
Query: 472 KTRKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSYSKNLKPSSET 531
T+K +D DEE D + ++ + EN + ++ + + S S + SS +
Sbjct: 996 TTKKETEVSD-GEDEESDSSSKCSLYA-----DSDGENDSTSDSESSSSSSSSSSSSSSS 1049
Query: 532 KTQKGLFSDEEDSEDLFSSQSASNLKGASLLPGKLP 567
+ S E SED + + L AS P ++P
Sbjct: 1050 SSSSSSSSSESSSEDEEEEERPAALPSASPPPREVP 1085
Score = 35.4 bits (80), Expect = 0.36
Identities = 104/538 (19%), Positives = 177/538 (32%), Gaps = 100/538 (18%)
Query: 220 DTEEEKEEEESDEDFAHHSDNEQ-NQHTTQMSDEEED-----DDGCDLFADSEKEEEDIE 273
D E K + + + FA S+ E+ +Q ++ DEE+D D+ + D+ K+E ++
Sbjct: 945 DEERGKTQGKHRKSFALDSEGEEASQESSSEKDEEDDEEDEEDEDREEAVDTTKKETEVS 1004
Query: 274 DIEENTRPKRSRPTSFADELAARIKGDAMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPS 333
D E+ S+ + +AD S
Sbjct: 1005 DGEDEESDSSSKCSLYAD-----------------------------------------S 1023
Query: 334 DDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEASQDRQAGASVKE 393
D E D+ T + S S S S+ +E ++ + A++
Sbjct: 1024 DGENDS-------TSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAAL-- 1074
Query: 394 ESSSSKPGKKIPAGA-VSVFLGDTDVFGAASVPSLKE----PQKPEQPTPRKSPYGP--- 445
S+S P +++P V + + + V L E P +P PT P P
Sbjct: 1075 -PSASPPPREVPVPTPAPVEVPVPERVAGSPVTPLPEQEASPARPAGPTEESPPSAPLRP 1133
Query: 446 --PPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTADIFGDEEGDLFKEKAVASPEATV 503
PP G D+ P P K R+ T E + P+A
Sbjct: 1134 PEPPAGPPAPAPRPDERPSSPIPLLPPPKKRR--KTVSFSAIEVVPAPEPPPATPPQAKF 1191
Query: 504 SQTDENKA-----RAEKKVTLSYSKNLKPSSETKTQ--------KGLFSDEEDSED---- 546
KA R + + L ++ +K E ++ +G ++EE++E
Sbjct: 1192 PGPASRKAPRGVERTIRNLPLDHASLVKSWPEEVSRGGRSRAGGRGRLTEEEEAEPGTEV 1251
Query: 547 ----LFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQREEK 602
L +G LP + + DE E + +L +
Sbjct: 1252 DLAVLADLALTPARRGLPALPAVEDSEATETSDEAERPRPLLSHILLEHNYALAVKPTPP 1311
Query: 603 AKASELSKK-KASALLFSSDEEWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTS 661
A A + A A LFSS + + A + +A EP+ Q +E +
Sbjct: 1312 APALRPPEPVPAPAALFSSPADEVLEAPEVVVAEAE----EPKPQQLQQQREEGEEEGEE 1367
Query: 662 LFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVSE 719
EE++E+ + DS + L + S PP PP + E SE
Sbjct: 1368 EGEEEEEE-----SSDSSSSSDGEGALRRRSLRSHARRRRPPPPPPPPPPRAYEPRSE 1420
Score = 33.9 bits (76), Expect = 1.1
Identities = 46/222 (20%), Positives = 87/222 (39%), Gaps = 24/222 (10%)
Query: 101 DEEVEEPVLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDS 160
+E+ ++P + EA + + T+ K + K Q LDS E+ ++ +
Sbjct: 919 EEDEDDPEQEKEAGEPGRPGTKPPKRDEERGKTQGKHRKSF-ALDSEGEEASQESSSEKD 977
Query: 161 EEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVD 220
EEDD + E ++ +D ++ +V GE +E S S + S+
Sbjct: 978 EEDDEEDEED---EDREEAVDTT----------KKETEVSDGE---DEESDSSSKCSLYA 1021
Query: 221 TEEEKEEEESDEDFAHHSDNEQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTR 280
+ + + SD + + S + + ++ S + ++ E+EEE + +
Sbjct: 1022 DSDGENDSTSDSESS--SSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASP 1079
Query: 281 PKRSRPTSFADELAARIKGDAMGRVDEEPTT-LPSGEAKPRK 321
P R P A ++ RV P T LP EA P +
Sbjct: 1080 PPREVPV----PTPAPVEVPVPERVAGSPVTPLPEQEASPAR 1117
Score = 33.1 bits (74), Expect = 1.8
Identities = 52/229 (22%), Positives = 92/229 (40%), Gaps = 36/229 (15%)
Query: 594 SLQAQREEKAKASELSKKKASALLFSSDEEWNIPASQTHLASDSRSKGEPRDSGTLQSQE 653
S + +R+E ++ SE S++K ++E+ + P + + GEP GT +
Sbjct: 892 SFKVKRKEPSEISEASEEKRPRPSTPAEEDEDDPEQE-------KEAGEPGRPGTKPPKR 944
Query: 654 AKAVKKTSLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKK 713
+ KT + K FA+ + ++ +Q S +++ D +V T K
Sbjct: 945 DEERGKT----QGKHRKSFALDSEGEEASQESSSEKDEEDDEEDEEDEDREEAVD--TTK 998
Query: 714 KETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQE 773
KET SD E++E+ S+K SL A+S+ E T ++
Sbjct: 999 KETE-------VSDGEDEESD----------SSSKCSL------YADSDGENDSTSDSES 1035
Query: 774 TVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEV 822
+ S SSSS + + S +EEE++ P +EV
Sbjct: 1036 SSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPPPREV 1084
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 55.8 bits (133), Expect = 3e-07
Identities = 124/661 (18%), Positives = 240/661 (36%), Gaps = 95/661 (14%)
Query: 196 QEDVGLGELSSE-EGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNQHTTQMSDEEE 254
++D+ L L++E EG+ + ++ +K++E+ +DF ++ + + + +
Sbjct: 14 KDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQGIK 73
Query: 255 DDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDAMGRVDEEPTTLPS 314
D +E EE+ ++ + ++ + SF D + L
Sbjct: 74 ADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDN---------------DSEELED 118
Query: 315 GEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEE 374
++K +KT K K E + SDD++D P K G S K +EDE+
Sbjct: 119 KDSKSKKTAKPKVEMYSGSDDDDDFNKLPKK---------AKGKAQKSNKKWDGSEEDED 169
Query: 375 -SDLFTEASQDRQAGASVKE------------ESSSSKPGKKIPAGAVSVFLGDTDVFGA 421
S E S+ +G S E ++ +KPG I +G D D
Sbjct: 170 NSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGN-----EDDDASFK 224
Query: 422 ASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTAD 481
+ K+ +K E+ ++ L + ++ + S K + +
Sbjct: 225 IKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSK 284
Query: 482 IFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSYSKNLKPSSETKTQKGLFSDE 541
+ D E+ +P A + +K + +KK K K E + +KG
Sbjct: 285 VTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKK----KKKGEKEEKEKEKKKG----- 335
Query: 542 EDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEE--DNLFGGTAAKKQTLSLQAQR 599
S + +K KL E+EE L A +K+ L+ ++
Sbjct: 336 ---------PSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEK 386
Query: 600 EEKAKASELSKKKASALLFSSDEEWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKK 659
E+ K E +K+ + L + S+ + R TL+ +A+ V+
Sbjct: 387 RERKKQKEKERKERL-------------KKEGKLLTKSQREARARAEATLKLLQAQGVEV 433
Query: 660 TSLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVSE 719
S K+ ++ + +K+ + L +V L + +K+ET
Sbjct: 434 PSKDSLPKKRPIY----EDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEET--- 486
Query: 720 APPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHSD 779
PP + +EEE G+ + + S +E+ K V KE +E + D
Sbjct: 487 -PPPVEPEEEEDTEDAGLDDWE-AMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEED 544
Query: 780 LFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQ-----NIIQAPQKEVGKGCDPDAHPKS 834
S ++G ++ DEE++K+ D+ + + P KE+ + D+
Sbjct: 545 EESEEEEEEEGESEGSEG-----DEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDR 599
Query: 835 T 835
T
Sbjct: 600 T 600
Score = 41.2 bits (95), Expect = 0.007
Identities = 76/436 (17%), Positives = 176/436 (40%), Gaps = 57/436 (13%)
Query: 108 VLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANG 167
V + +AEK E+E+ + +E + K++E ++ +Q K EE+
Sbjct: 228 VAQKKAEKKERERKKRDEEKAKLRKLKEKE----ELETGKKDQSKQKESQRKFEEETVKS 283
Query: 168 RVEL---ILEPKDLYIDRPLPYLIGSKLFMEQED----VGLGELSSEEGSVGSDRGSIVD 220
+V + ++ + + P ++ +++D G E +E G + ++
Sbjct: 284 KVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKA 343
Query: 221 TEEEKEEEESDEDFAHHSDNEQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTR 280
+E + + +E+ + E+ + ++ + ++++ + ++E + ++ E R
Sbjct: 344 MQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLE---QEKRERKKQKEKERKER 400
Query: 281 PKRSRPTSFADELAARIKGDA-MGRVDEEPTTLPSGEAKPRK--TLKEKKERRTPSDDEE 337
K+ + AR + +A + + + +PS ++ P+K ++KK ++ P E
Sbjct: 401 LKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLES 460
Query: 338 DNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEASQDRQ-AGASVKEESS 396
+ +L + +G+ + E+ + E +D + AG E +
Sbjct: 461 KEVSESMELC----------AAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMA 510
Query: 397 SSKPGKKIPAGAVSVFLGDTDVFGAASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDG 456
S + +K+ V + + + P +E ++ E+ +S G + +G
Sbjct: 511 SDEETEKVEGNKVHIEVKEN--------PEEEEEEEEEEEEDEESEEEEEEEGESEGSEG 562
Query: 457 DDDDDFFS-------APHSKPSKTRKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDEN 509
D++D+ S KPSK + ++D D + D KE+ D+
Sbjct: 563 DEEDEKVSDEKDSGKTLDKKPSK----EMSSDSEYDSDDDRTKEERA---------YDKA 609
Query: 510 KARAEKKVTLSYSKNL 525
K R EK+ L +SKN+
Sbjct: 610 KRRIEKR-RLEHSKNV 624
Score = 39.7 bits (91), Expect = 0.019
Identities = 94/474 (19%), Positives = 183/474 (38%), Gaps = 59/474 (12%)
Query: 110 KAEAEKTEQEKTREQKEVDLIPKVQEA--VNYGLQVLDSAFEQLDIKAGN---------- 157
K +A+K+ ++ +++ D K++E +N + D + E L + G
Sbjct: 151 KGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGP 210
Query: 158 ---SDSEEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSS-EEGSVGS 213
S +E+DDA+ +++ + + K +R + ++E L +L EE G
Sbjct: 211 NIESGNEDDDASFKIKTVAQKKAEKKER-------ERKKRDEEKAKLRKLKEKEELETGK 263
Query: 214 DRGSIVDTEEEKEEEESDE-----DFAHHSDNEQNQHTTQMSDEEEDDDGCDLFADSEKE 268
S + K EEE+ + D +E+ T + E+D++G D +K+
Sbjct: 264 KDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAA--EDDNEGDKKKKDKKKK 321
Query: 269 EEDIEDIEENTRPKRSRPTSFADELAARIKGDAMGRVDEEPTTLPSGEAKPRKTLKEKKE 328
+ + E+ E+ + S+ T A + +A+ ++ EE E + K L+E +
Sbjct: 322 KGEKEEKEKEKKKGPSKATVKAMQ-------EALAKLKEEEERQKREEEERIKRLEELEA 374
Query: 329 RRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEASQDRQAG 388
+R + E K +++ L GK L E+ EA+
Sbjct: 375 KRKEEERLEQEKRERKKQKEKERKE-----RLKKEGK-LLTKSQREARARAEATLKLLQA 428
Query: 389 ASVKEESSSSKPGK----------KIPAGAVSVFLGDT-DVFGAASVPSLKEPQKPEQPT 437
V+ S S P K KIP S + ++ ++ A V P+K E P
Sbjct: 429 QGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPP 488
Query: 438 P--RKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPS---KTRKVQSTADIFGDEEGDLFK 492
P + GL D + D++ +K K + + +EE + +
Sbjct: 489 PVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESE 548
Query: 493 EKAVASPEATVSQTDENKARAEKKVTLSYSKNLKPSSETKTQKGLFSDEEDSED 546
E+ E+ S+ DE + + + + KPS E + SD++ +++
Sbjct: 549 EEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKE 602
Score = 39.7 bits (91), Expect = 0.019
Identities = 56/257 (21%), Positives = 100/257 (38%), Gaps = 52/257 (20%)
Query: 98 RVYDEEVEEPVLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGN 157
R +E +E+ + + +K ++ K R +KE L+ K Q + + ++ +
Sbjct: 376 RKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPS 435
Query: 158 SDS-------EEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQ------EDVGLGEL 204
DS ED ++ LE K++ L + MEQ E E
Sbjct: 436 KDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVE---VMEQGVPEKEETPPPVEP 492
Query: 205 SSEEGS--VGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNQHTTQMSDEEEDDDGCDLF 262
EE + G D + ++EE E+ E ++ H + ++N + +EEE++D
Sbjct: 493 EEEEDTEDAGLDDWEAMASDEETEKVEGNK---VHIEVKENPEEEEEEEEEEEED----- 544
Query: 263 ADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDAMGRVDEEPTTLPSGEAKPRKT 322
+SE+EEE+ +G++ G +E S E KT
Sbjct: 545 EESEEEEEE--------------------------EGESEGSEGDEEDEKVSDEKDSGKT 578
Query: 323 LKEKKERRTPSDDEEDN 339
L +K + SD E D+
Sbjct: 579 LDKKPSKEMSSDSEYDS 595
Score = 35.4 bits (80), Expect = 0.36
Identities = 38/140 (27%), Positives = 59/140 (42%), Gaps = 15/140 (10%)
Query: 1153 GEASSDDDLFQSAKPKPAKKTNPFPLLEDEDDLFTDQKVKKNETKS--SSQQDVILTTQD 1210
G A + K K KK F DEDD+ + + E + + ++ V + +
Sbjct: 30 GAAKEQEPQKSKGKKKKEKKKQDF----DEDDILKELEELSLEAQGIKADRETVAVKPTE 85
Query: 1211 IFEDDIFATEAIKPSQKTREKEKTLESNLFDDN-IDIFADLTVKPKEKSKKKVEAKSIFD 1269
E++ + + K QK +++ FDDN + D K K+ +K KVE S D
Sbjct: 86 NNEEEFTSKDKKKKGQKGKKQS-------FDDNDSEELEDKDSKSKKTAKPKVEMYSGSD 138
Query: 1270 DDMDDIFSTGIQAKTTKPKS 1289
DD DD +AK KS
Sbjct: 139 DD-DDFNKLPKKAKGKAQKS 157
Score = 34.3 bits (77), Expect = 0.81
Identities = 57/277 (20%), Positives = 102/277 (36%), Gaps = 35/277 (12%)
Query: 728 EEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLL----TRSAQETVKHSDLFSS 783
E+E + G K +KK + E + E +G+ T + + T + + F+S
Sbjct: 34 EQEPQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQGIKADRETVAVKPTENNEEEFTS 93
Query: 784 SSPWDKGTKPRTKTVLSLFDEE-EDKMEDQNIIQAPQKEVGKGCDPD------------- 829
KG K + ++ EE EDK P+ E+ G D D
Sbjct: 94 KDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGK 153
Query: 830 ---AHPKSTGVFQDEE----------LLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSL 876
++ K G +DE+ + S + ++D + G KK + +P
Sbjct: 154 AQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIE 213
Query: 877 FGDDEDDDLFS-SAKSQPLVQEKKRVVKK-DHSVNSFKNQKHPESIQGSKEKGIWKPETP 934
G+++DD F +Q ++K+R KK D + K E ++ K+ + E+
Sbjct: 214 SGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQ 273
Query: 935 Q--ANLAINPAALLPTAASQISEVKPVLPELAFPSSE 969
+ + + T SE K P A +E
Sbjct: 274 RKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNE 310
Score = 32.7 bits (73), Expect = 2.4
Identities = 52/208 (25%), Positives = 75/208 (36%), Gaps = 36/208 (17%)
Query: 735 LGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPR 794
+G K +K +S K+ + D +E EG QE K KG K +
Sbjct: 1 MGKKQKNKSEDSTKDDIDL---DALAAEIEGAGAAKEQEPQK-----------SKGKKKK 46
Query: 795 TKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGCDPDAHPKSTGVFQDEELLFSHKLQK--- 851
K FDE++ E + + Q G D + ++ E F+ K +K
Sbjct: 47 EKKKQD-FDEDDILKELEELSLEAQ-----GIKADRETVAVKPTENNEEEFTSKDKKKKG 100
Query: 852 ---------DNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDD---LFSSAKSQPLVQEKK 899
DND + +K K +P V G D+DDD L AK + KK
Sbjct: 101 QKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKK 160
Query: 900 RVVKKDHSVNSFKNQKHPESIQGSKEKG 927
++ NS K K I S E G
Sbjct: 161 WDGSEEDEDNS-KKIKERSRINSSGESG 187
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 55.8 bits (133), Expect = 3e-07
Identities = 85/382 (22%), Positives = 150/382 (39%), Gaps = 27/382 (7%)
Query: 589 KKQTLSLQAQREEKAKASELSKKKASALLFSSDEEWNIPASQTHLASDSRSKGEPRDSGT 648
KK T + +++EK + L+K++ A EE + KG ++
Sbjct: 182 KKATHKEKIEKKEKPETKTLAKEQKKAKTAEKSEE----------KTKKEVKGGKQEKVK 231
Query: 649 LQSQEAKAVKKTSLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVP 708
+ + K V+KT ++KED A ++K Q + D+ G L ++P
Sbjct: 232 QTAAKVKEVQKTPSKPKEKEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAIP 291
Query: 709 P--ATKKKETVSEAPPLLFSDE-EEKEAQLGVKSVDKKVES---AKESLKFGRTDVAESE 762
P T++ + A P L E E+K+A+ V S KK E K+S K DV E +
Sbjct: 292 PPLPTEQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDV-EKK 350
Query: 763 KEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFD----EEEDKMEDQNIIQAP 818
+ G + + Q TVK + ++ K +TK + ++E K + ++P
Sbjct: 351 EPGKASETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHVEPAKSP 410
Query: 819 QKEVGKGCDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFG 878
+KE D K+ ++ + K + ++ + + S
Sbjct: 411 KKEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTTKTVEQEIRKEKSGKTSSIL 470
Query: 879 DDEDDDLFSSAKSQPLVQEKKRVVKKDHSVNSFKNQKHPE--SIQGSKEKGIWKPETPQA 936
D++ K ++EK+ KKD ++ + P+ +QG KE+ KPE PQ
Sbjct: 471 KDKEPIKGKEEKVPASLKEKEPETKKDEKMSKAGKEVKPKPPQLQGKKEE---KPE-PQI 526
Query: 937 NLAINPAALLPTAASQISEVKP 958
PA + VKP
Sbjct: 527 KKEAKPAISEKVQIHKQDIVKP 548
Score = 52.4 bits (124), Expect = 3e-06
Identities = 121/611 (19%), Positives = 229/611 (37%), Gaps = 113/611 (18%)
Query: 207 EEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNQHTTQMSDEEEDDDGCDLFADSE 266
++G +D+G I + K+E D+ + Q ++E+ + E
Sbjct: 122 DDGDEDTDKGEIDEPPLRKKEIHKDKTEKQEKPERKIQTKVTHKEKEKGKEKVREKEKPE 181
Query: 267 KEEEDIEDIEENTRP---------KRSRPTSFADELAAR-IKGDAMGRVDEEPTTLPSGE 316
K+ E IE+ +P K+++ ++E + +KG +V + + +
Sbjct: 182 KKATHKEKIEKKEKPETKTLAKEQKKAKTAEKSEEKTKKEVKGGKQEKVKQTAAKVKEVQ 241
Query: 317 AKPRKTL-KEKKERRTPSDDEEDNLFA----------------------PPKLTDEDFSP 353
P K KE KE+ S E+ + +A PP L E S
Sbjct: 242 KTPSKPKEKEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPPPLPTEQASR 301
Query: 354 FGSGGGLFSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSSS-KPGKKIPAGAVSVF 412
+G + + E + +E + + K E ++ KK P A
Sbjct: 302 PTPASPALEEKEG--EKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEPGKASETK 359
Query: 413 LGDTDVFGAASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSK 472
G + AA + K+ +K + +K P G + H +P+K
Sbjct: 360 QGTVKI--AAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEK---------KEKHVEPAK 408
Query: 473 TRKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSYSKNLKPSSETK 532
+ K KE +V S + ++T+ K E+ +S K + E K
Sbjct: 409 SPK----------------KEHSVPSDKQVKAKTERAK---EEIGAVSIKKAVPGKKEEK 449
Query: 533 TQKGLFSDEEDSEDLFSSQSASNLKGASLLPG---KLPTSVSLFDDEDEEDNLF--GGTA 587
T K + E++ S +++S LK + G K+P S+ + E ++D G
Sbjct: 450 TTKTV---EQEIRKEKSGKTSSILKDKEPIKGKEEKVPASLKEKEPETKKDEKMSKAGKE 506
Query: 588 AKKQTLSLQAQREEKAKASELSKKKASALLFSSDEEWNIPASQTHLASDSRSKGEPRDSG 647
K + LQ ++EEK + ++ K+ A+ E+ I + S G+P +
Sbjct: 507 VKPKPPQLQGKKEEKPE-PQIKKEAKPAI----SEKVQIHKQDIVKPEKTVSHGKPEEK- 560
Query: 648 TLQSQEAKAVKKTSLFE-----EDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGS 702
L+ +A ++KT+ + E +E + +I D K T + +
Sbjct: 561 VLKQVKAVTIEKTAKPKPTKKAEHREREPPSIKTDKPKPTPKGT---------------- 604
Query: 703 PPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESE 762
+ V + KKK +SE +E KE ++KV + KESL+ +V ++E
Sbjct: 605 --SEVTESGKKKTEISE--------KESKEKADMKHLREEKVSTRKESLQL--HNVTKAE 652
Query: 763 KEGLLTRSAQE 773
K +++ ++
Sbjct: 653 KPARVSKDVED 663
Score = 46.2 bits (108), Expect = 2e-04
Identities = 113/525 (21%), Positives = 193/525 (36%), Gaps = 96/525 (18%)
Query: 452 DDDDGDDDDD--------------FFSAPHSKPSKTRKVQSTADIFGDEEG-DLFKEKAV 496
+DDDGD+D D + RK+Q+ E+G + +EK
Sbjct: 120 EDDDGDEDTDKGEIDEPPLRKKEIHKDKTEKQEKPERKIQTKVTHKEKEKGKEKVREKEK 179
Query: 497 ASPEATVSQTDENKARAEKKVTLSYSKNLKPS--SETKTQKGLFSDEEDSEDLFSSQSAS 554
+AT + E K + E K K K + SE KT+K + +++ Q+A+
Sbjct: 180 PEKKATHKEKIEKKEKPETKTLAKEQKKAKTAEKSEEKTKKEVKGGKQEK----VKQTAA 235
Query: 555 NLKGASLLPG-------KLPTSVSLFDDEDEE-------DNLFGGTAAKKQTLSL----- 595
+K P K +VS + +D+ D G Q+ ++
Sbjct: 236 KVKEVQKTPSKPKEKEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPPPLP 295
Query: 596 --QAQR--------EEKAKASELSKKKASALLFSSDEEWNIPASQTHLASDSRSKGEPRD 645
QA R EEK + ++KK ++ ++E S+ A D K +
Sbjct: 296 TEQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEPGKA 355
Query: 646 SGTLQSQEAKAVKKTSLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPT 705
S T Q A + + +E KED KKT++ + E + G
Sbjct: 356 SETKQGTVKIAAQAAAKKDEKKED---------SKKTKKPA---EVEQPKGKKQEKKEKH 403
Query: 706 SVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEG 765
P + KKE + + + E + ++G S+ K V KE K +T E KE
Sbjct: 404 VEPAKSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEE-KTTKTVEQEIRKE- 461
Query: 766 LLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKG 825
++ K S + P KG + K SL ++E + +D+ + +A GK
Sbjct: 462 -------KSGKTSSILKDKEP-IKGKE--EKVPASLKEKEPETKKDEKMSKA-----GK- 505
Query: 826 CDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDL 885
+ PK + +E +++K+ P + K +++P G E+
Sbjct: 506 ---EVKPKPPQLQGKKEEKPEPQIKKEAKPAISEKVQIHKQDIVKPEKTVSHGKPEE--- 559
Query: 886 FSSAKSQPLVQEKKRVVKKDHSVNSFKNQKH----PESIQGSKEK 926
+ L Q K ++K K +H P SI+ K K
Sbjct: 560 ------KVLKQVKAVTIEKTAKPKPTKKAEHREREPPSIKTDKPK 598
Score = 37.0 bits (84), Expect = 0.13
Identities = 80/387 (20%), Positives = 144/387 (37%), Gaps = 57/387 (14%)
Query: 102 EEVEEPVLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFE--QLDIK-AGNS 158
EE E KAE + T + K +E++++ + + A++ + A E Q +K A +
Sbjct: 310 EEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEPGKASETKQGTVKIAAQA 369
Query: 159 DSEEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSI 218
+++D+ + +P + +++P G K +++ V + +E SV SD+
Sbjct: 370 AAKKDEKKEDSKKTKKPAE--VEQPK----GKKQEKKEKHVEPAKSPKKEHSVPSDKQVK 423
Query: 219 VDTEEEKEEEESDEDFAHHSDNEQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEEN 278
TE KEE + ++ + TT+ ++E + + K++E I+ EE
Sbjct: 424 AKTERAKEEIGA-VSIKKAVPGKKEEKTTKTVEQEIRKEKSGKTSSILKDKEPIKGKEEK 482
Query: 279 TRP--KRSRPTSFADELAARIKGDA-------MGRVDEEPTTLPSGEAKP---------- 319
K P + DE ++ + G+ +E+P EAKP
Sbjct: 483 VPASLKEKEPETKKDEKMSKAGKEVKPKPPQLQGKKEEKPEPQIKKEAKPAISEKVQIHK 542
Query: 320 ----------------RKTLK-------EKKERRTPSDDEEDNLFAPPKLTDEDFSPFGS 356
K LK EK + P+ E PP + + P
Sbjct: 543 QDIVKPEKTVSHGKPEEKVLKQVKAVTIEKTAKPKPTKKAEHREREPPSIKTDKPKPTPK 602
Query: 357 G-GGLFSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGD 415
G + GK + ++ES + R+ S ++ES K A
Sbjct: 603 GTSEVTESGKKKTEISEKESKEKADMKHLREEKVSTRKESLQLHNVTKAEKPA----RVS 658
Query: 416 TDVFGAASVPSLKEPQKPEQPTPRKSP 442
DV + KE + PT +KSP
Sbjct: 659 KDVEDVPASKKAKEGTEDVSPTKQKSP 685
>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
precursor [Homo sapiens]
Length = 513
Score = 55.1 bits (131), Expect = 4e-07
Identities = 106/494 (21%), Positives = 185/494 (37%), Gaps = 75/494 (15%)
Query: 213 SDRGSIVDTEEEKEEEESDEDFAHHS-DNEQNQHTTQMS--------------DEEEDDD 257
S GS V +EE+ E+ SD + ++ +Q+ +++ D++EDD
Sbjct: 50 SSEGSKVSSEEQANEDPSDSTQSEEGLGSDDHQYIYRLAGGFSRSTGKGGDDKDDDEDDS 109
Query: 258 GCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDAMGRVDEEPTTLPSGEA 317
G D F D + +D +E + D + A + G+ + TT S E
Sbjct: 110 GDDTFGDDDSGPGP-KDRQEGGNSRLGSDEDSDDTIQASEESAPQGQDSAQDTTSESREL 168
Query: 318 KPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDL 377
+ K E + + E ++E + GS G G DDE +SD
Sbjct: 169 DNEDRVDSKPEGGDSTQESE---------SEEHWVGGGSDGESSHGDGSELDDEGMQSD- 218
Query: 378 FTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSLKEPQKPEQPT 437
D ++ S + S + G K + +T G + + + P +
Sbjct: 219 ------DPESIRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQL-----LEHPSRKI 267
Query: 438 PRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTADIFGDEEGDLFKEKAVA 497
RKS + ++DD + DD + K T S ++ ++
Sbjct: 268 FRKS-------RISEEDDRSELDDNNTMEEVKSDSTENSNS-------------RDTGLS 307
Query: 498 SPEATVSQTDENKARAEKKVTLSYSKNLK-PSSETKTQKGLFSDEEDSEDLFSSQSASNL 556
P +++ +++ ++ S+N+ PSSE+ + L S E SS+S +
Sbjct: 308 QPRR--DSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQEN------SSESQEEV 359
Query: 557 KGASLLPGKLPTSVSLFDDED----EEDNLFGGTAAKKQTLSLQAQRE--EKAKASELSK 610
S PT+ + D ED EED+ + +K ++ QA E E SE S
Sbjct: 360 VSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESP 419
Query: 611 KKASALLFSSDEEWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDKEDD 670
+ SS E +S S+ S E DS + S +K ++ + E+D
Sbjct: 420 ESPEDENSSSQEGLQSHSSSAESQSE-ESHSEEDDSDSQDSSRSKEDSNSTESKSSSEED 478
Query: 671 --LFAIAKDSQKKT 682
L I +S+K T
Sbjct: 479 GQLKNIEIESRKLT 492
Score = 39.3 bits (90), Expect = 0.025
Identities = 97/469 (20%), Positives = 168/469 (35%), Gaps = 80/469 (17%)
Query: 303 GRVDEEPTT-LPSGEAKP-RKTLKEKKERRTPSDD--EEDNLFAPPKLTDEDFSPFGSGG 358
G + + PT L S E+ K E++ PSD E+ L + D + +GG
Sbjct: 35 GHLAQAPTPPLESSESSEGSKVSSEEQANEDPSDSTQSEEGLGSD----DHQYIYRLAGG 90
Query: 359 GLFSGGKGLFDDEDEESDLFTEASQDRQAGASVK--EESSSSKPGKKIPAGAVSVFLGDT 416
S GKG D +D+E D + D +G K +E +S+ G D+
Sbjct: 91 FSRSTGKGGDDKDDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSD----------EDS 140
Query: 417 DVFGAASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKV 476
D AS S + Q Q T +S + D++D S P S
Sbjct: 141 DDTIQASEESAPQGQDSAQDTTSES------------RELDNEDRVDSKPEGGDSTQESE 188
Query: 477 QSTADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSYSKNLKPSSETKTQKG 536
+ G +G+ + + D R+E+ + S +K + G
Sbjct: 189 SEEHWVGGGSDGESSHGDGSELDDEGMQSDDPESIRSERGNSRMNSAGMK-----SKESG 243
Query: 537 LFSDEEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAK------- 589
S++ +++D SQ + P + S +ED+ L +
Sbjct: 244 ENSEQANTQDSGGSQLLEH-------PSRKIFRKSRISEEDDRSELDDNNTMEEVKSDST 296
Query: 590 -----KQTLSLQAQREEKAKASELSKKKASALLFSSDEEWNI--PASQTHLASDSRSKGE 642
+ T Q +R+ K + E SK+ S +E N+ P+S++ ++ S+
Sbjct: 297 ENSNSRDTGLSQPRRDSKGDSQEDSKEN-----LSQEESQNVDGPSSESSQEANLSSQEN 351
Query: 643 PRDSGTLQSQEAKA--VKKTSLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLF 700
+S E++ T+ + ED+ED + S + S E+ DS S
Sbjct: 352 SSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESS-- 409
Query: 701 GSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKE 749
+ E E+P ++E +Q G++S ES E
Sbjct: 410 --------ESLNFSEESPESP-----EDENSSSQEGLQSHSSSAESQSE 445
Score = 35.4 bits (80), Expect = 0.36
Identities = 42/186 (22%), Positives = 82/186 (44%), Gaps = 26/186 (13%)
Query: 157 NSDSEEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRG 216
N S+E+ + + E++ E + D P P + +QED SSEE S +
Sbjct: 345 NLSSQENSSESQEEVVSESRG---DNPDPT---TSYVEDQEDSD----SSEEDSSHTLSH 394
Query: 217 SIVDTEEEKEEEESDE--DFAHHS-DNEQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIE 273
S ++ EE+ + ES E +F+ S ++ ++++++ + + ++ EED
Sbjct: 395 SKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDS 454
Query: 274 DIEENTRPKRSRPTSFADELAARIKGDAMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPS 333
D ++++R K D + K + EE L + E + RK + + P
Sbjct: 455 DSQDSSRSKE-------DSNSTESKSSS-----EEDGQLKNIEIESRKLTVDAYHNK-PI 501
Query: 334 DDEEDN 339
D++DN
Sbjct: 502 GDQDDN 507
Score = 33.9 bits (76), Expect = 1.1
Identities = 89/452 (19%), Positives = 171/452 (37%), Gaps = 55/452 (12%)
Query: 486 EEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSYSKNLKPSSETKTQKGLFSDEED-S 544
E+ + +K +P + ++ ++ KV+ N PS T++++GL SD+
Sbjct: 28 EDSEEWKGHLAQAPTPPLESSESSEG---SKVSSEEQANEDPSDSTQSEEGLGSDDHQYI 84
Query: 545 EDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQREEKAK 604
L S S KG D +D+ED+ T + R+E
Sbjct: 85 YRLAGGFSRSTGKGGD-------------DKDDDEDDSGDDTFGDDDSGPGPKDRQEGGN 131
Query: 605 ASELSKKKASALLFSSDEEWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTSLFE 664
+ S + + + +S+E + P Q A D+ S E R+ ++K S E
Sbjct: 132 SRLGSDEDSDDTIQASEE--SAPQGQDS-AQDTTS--ESRELDNEDRVDSKPEGGDSTQE 186
Query: 665 EDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVSEAPPLL 724
+ E+ D + S L ++ + S P S+ S
Sbjct: 187 SESEEHWVGGGSDGESSHGDGSELDDEGMQS------DDPESIRSERGNSRMNSAGMKSK 240
Query: 725 FSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVA-ESEKEGLLTRSAQETVKHSDLFSS 783
S E ++A + +E + F ++ ++ E ++ L + E VK SD +
Sbjct: 241 ESGENSEQANTQDSGGSQLLEHPSRKI-FRKSRISEEDDRSELDDNNTMEEVK-SDSTEN 298
Query: 784 SSPWDKG-TKPRTKTVLSLFDEEED-----KMEDQNIIQAPQKEVGKGCDPDAHPKSTGV 837
S+ D G ++PR S D +ED E+ + P E + + + S+
Sbjct: 299 SNSRDTGLSQPRRD---SKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSS-- 353
Query: 838 FQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQE 897
+ +E + S + DP T +E S +++ S +KS+ +E
Sbjct: 354 -ESQEEVVSESRGDNPDP---------TTSYVEDQEDSDSSEEDSSHTLSHSKSES--RE 401
Query: 898 KKRVVKKDHSVN-SFKNQKHPESIQGSKEKGI 928
++ + S+N S ++ + PE S ++G+
Sbjct: 402 EQADSESSESLNFSEESPESPEDENSSSQEGL 433
Score = 30.8 bits (68), Expect = 9.0
Identities = 36/166 (21%), Positives = 68/166 (40%), Gaps = 17/166 (10%)
Query: 102 EEVEEPVLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAG----- 156
E+ +E + + E++ + + +E +L + + + V +S + D
Sbjct: 319 EDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQ 378
Query: 157 -NSDSEEDDAN-----GRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGS 210
+SDS E+D++ + E E D L + S E E+ SS+EG
Sbjct: 379 EDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENS-----SSQEG- 432
Query: 211 VGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNQHTTQMSDEEEDD 256
+ S S EE EE D D S ++++ ++T+ E+D
Sbjct: 433 LQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEED 478
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 55.1 bits (131), Expect = 4e-07
Identities = 106/501 (21%), Positives = 185/501 (36%), Gaps = 95/501 (18%)
Query: 95 IENRVYDEEVEEPVLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIK 154
I +++ +VE P LK + K +E E K D +++EA+ + L + ++ +
Sbjct: 432 ISSKIQKPKVEAPKLKVQ-HKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKE 490
Query: 155 AGNSDSEEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSD 214
A EE +A E+ + + P E+ EEG
Sbjct: 491 AAEEKEEEPEAEEE-EVAAKKSPVKATAP-------------------EVKEEEGEK--- 527
Query: 215 RGSIVDTEEEKEEEESDEDFAHHSDNEQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIED 274
+ EE +EEEE +++ A E+ + S E+E+ + + ++E E E+ E
Sbjct: 528 -----EEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEA 582
Query: 275 IEENTRPKRSRPTSFADELAARIKGD----AMGRVDEEPTTLPSGEAKPRKTLKEKKERR 330
EE ++S + +EL A K + A V + P P+ ++EK +
Sbjct: 583 KEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSP 642
Query: 331 TPSDDEEDNLFAP-PKLTDED--------------------FSPFGSGGGLFSGGKGLFD 369
P E+ +P PK E+ SP GKG +
Sbjct: 643 VPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKG--E 700
Query: 370 DEDEESDLFTEASQDRQAGASVKEESSSSKPGKK-----IPAGAVSVFLGDTDVFGAASV 424
++EE EA ++ + KEE P KK + AV+ + T
Sbjct: 701 QKEEEEKEVKEAPKEEK--VEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLE 758
Query: 425 PSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTADIFG 484
KE KP Q K G + G +++ S +K S+ + ++ G
Sbjct: 759 KETKEEGKPLQQEKEKEKAG--------GEGGSEEEG--SDKGAKGSRKEDIAVNGEVEG 808
Query: 485 DEE---------GDLFKEKAVASPEATVSQTDENKA--RAEKKVTLSYSKNLKPSSETKT 533
EE +EK V + +S DE K ++E+KV + TKT
Sbjct: 809 KEEVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVV-----------TKT 857
Query: 534 QKGLFSDEEDSEDLFSSQSAS 554
+ + S+ D + ++S +
Sbjct: 858 VEKITSEGGDGATKYITKSVT 878
Score = 38.5 bits (88), Expect = 0.043
Identities = 97/466 (20%), Positives = 179/466 (38%), Gaps = 68/466 (14%)
Query: 373 EESDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSLKEPQK 432
EE+ + E S+ +A ++ EE + S +K A+ +EP+
Sbjct: 458 EETKVEDEKSEMEEALTAITEELAVSMKEEK----------------KEAAEEKEEEPEA 501
Query: 433 PEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTADIFGDEEGDLFK 492
E+ K +++G+ +++ + + K + ++EG K
Sbjct: 502 EEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEK 561
Query: 493 EKAVASPEATVSQTD--ENKARAEKKVTLSYSKNLKPSSETKTQKGLFSDE--EDSEDLF 548
E+ T ++ + E +A+ EKKV + S E T++ L +D E E
Sbjct: 562 EEGEQEEGETEAEAEGEEAEAKEEKKVE-------EKSEEVATKEELVADAKVEKPEKAK 614
Query: 549 SSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQREEKAKASEL 608
S S ++ GK P S +++ + K ++ ++ EEK K S +
Sbjct: 615 SPVPKSPVEEK----GKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGK-SPV 669
Query: 609 SKKKASALLFSSDEEWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDKE 668
SK +E+ P ++ + +++SK E G + +E K VK+ +E+K
Sbjct: 670 SKSPV-------EEKAKSPVPKSPV-EEAKSKAEV-GKGEQKEEEEKEVKEAP--KEEKV 718
Query: 669 DDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVSEAPPLLFSDE 728
+ KD +K + S + E+ V ++ S + +KET E PL E
Sbjct: 719 EKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHL-----EKETKEEGKPLQQEKE 773
Query: 729 EEKEAQLGVKSVDKKVESAKESLK---------FGRTDVAESEKEGLLTRSAQETVKHSD 779
+EK G + + AK S K G+ +V + KE R ++ V +
Sbjct: 774 KEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVTNG 833
Query: 780 LFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKG 825
L S + KG D+ E+K+ ++ E G G
Sbjct: 834 LDLSPADEKKGG-----------DKSEEKVVVTKTVEKITSEGGDG 868
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 55.1 bits (131), Expect = 4e-07
Identities = 106/501 (21%), Positives = 185/501 (36%), Gaps = 95/501 (18%)
Query: 95 IENRVYDEEVEEPVLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIK 154
I +++ +VE P LK + K +E E K D +++EA+ + L + ++ +
Sbjct: 56 ISSKIQKPKVEAPKLKVQ-HKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKE 114
Query: 155 AGNSDSEEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSD 214
A EE +A E+ + + P E+ EEG
Sbjct: 115 AAEEKEEEPEAEEE-EVAAKKSPVKATAP-------------------EVKEEEGEK--- 151
Query: 215 RGSIVDTEEEKEEEESDEDFAHHSDNEQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIED 274
+ EE +EEEE +++ A E+ + S E+E+ + + ++E E E+ E
Sbjct: 152 -----EEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEA 206
Query: 275 IEENTRPKRSRPTSFADELAARIKGD----AMGRVDEEPTTLPSGEAKPRKTLKEKKERR 330
EE ++S + +EL A K + A V + P P+ ++EK +
Sbjct: 207 KEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSP 266
Query: 331 TPSDDEEDNLFAP-PKLTDED--------------------FSPFGSGGGLFSGGKGLFD 369
P E+ +P PK E+ SP GKG +
Sbjct: 267 VPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKG--E 324
Query: 370 DEDEESDLFTEASQDRQAGASVKEESSSSKPGKK-----IPAGAVSVFLGDTDVFGAASV 424
++EE EA ++ + KEE P KK + AV+ + T
Sbjct: 325 QKEEEEKEVKEAPKEEK--VEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLE 382
Query: 425 PSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTADIFG 484
KE KP Q K G + G +++ S +K S+ + ++ G
Sbjct: 383 KETKEEGKPLQQEKEKEKAG--------GEGGSEEEG--SDKGAKGSRKEDIAVNGEVEG 432
Query: 485 DEE---------GDLFKEKAVASPEATVSQTDENKA--RAEKKVTLSYSKNLKPSSETKT 533
EE +EK V + +S DE K ++E+KV + TKT
Sbjct: 433 KEEVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVV-----------TKT 481
Query: 534 QKGLFSDEEDSEDLFSSQSAS 554
+ + S+ D + ++S +
Sbjct: 482 VEKITSEGGDGATKYITKSVT 502
Score = 38.5 bits (88), Expect = 0.043
Identities = 97/466 (20%), Positives = 179/466 (38%), Gaps = 68/466 (14%)
Query: 373 EESDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSLKEPQK 432
EE+ + E S+ +A ++ EE + S +K A+ +EP+
Sbjct: 82 EETKVEDEKSEMEEALTAITEELAVSMKEEK----------------KEAAEEKEEEPEA 125
Query: 433 PEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTADIFGDEEGDLFK 492
E+ K +++G+ +++ + + K + ++EG K
Sbjct: 126 EEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEK 185
Query: 493 EKAVASPEATVSQTD--ENKARAEKKVTLSYSKNLKPSSETKTQKGLFSDE--EDSEDLF 548
E+ T ++ + E +A+ EKKV + S E T++ L +D E E
Sbjct: 186 EEGEQEEGETEAEAEGEEAEAKEEKKVE-------EKSEEVATKEELVADAKVEKPEKAK 238
Query: 549 SSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQREEKAKASEL 608
S S ++ GK P S +++ + K ++ ++ EEK K S +
Sbjct: 239 SPVPKSPVEEK----GKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGK-SPV 293
Query: 609 SKKKASALLFSSDEEWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDKE 668
SK +E+ P ++ + +++SK E G + +E K VK+ +E+K
Sbjct: 294 SKSPV-------EEKAKSPVPKSPV-EEAKSKAEV-GKGEQKEEEEKEVKEAP--KEEKV 342
Query: 669 DDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVSEAPPLLFSDE 728
+ KD +K + S + E+ V ++ S + +KET E PL E
Sbjct: 343 EKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHL-----EKETKEEGKPLQQEKE 397
Query: 729 EEKEAQLGVKSVDKKVESAKESLK---------FGRTDVAESEKEGLLTRSAQETVKHSD 779
+EK G + + AK S K G+ +V + KE R ++ V +
Sbjct: 398 KEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVTNG 457
Query: 780 LFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKG 825
L S + KG D+ E+K+ ++ E G G
Sbjct: 458 LDLSPADEKKGG-----------DKSEEKVVVTKTVEKITSEGGDG 492
>gi|19913408 DNA topoisomerase II, beta isozyme [Homo sapiens]
Length = 1621
Score = 52.4 bits (124), Expect = 3e-06
Identities = 75/294 (25%), Positives = 114/294 (38%), Gaps = 55/294 (18%)
Query: 452 DDDDGDDDDDFFSAPHSKPSKTRKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENKA 511
+DDD DDDDD + + KV+++ I D E + + E T S ++KA
Sbjct: 1373 EDDDADDDDD-----DNNDLEELKVKASP-ITNDGEDEFVPSDGLDKDEYTFSP-GKSKA 1425
Query: 512 RAEKKVTLSYSKNLK-----PSSETKTQKG---LFSDEEDSEDLFSSQSASNLKGASLLP 563
EK + S++ PS K++ S+EEDS +FS + LK +P
Sbjct: 1426 TPEKSLHDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSP--SFGLKQTDKVP 1483
Query: 564 GKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQREEKAKASELSKKKASALLFSSDEE 623
K AAKK S + K K + KK A+ SD E
Sbjct: 1484 SKT-------------------VAAKKGKPS--SDTVPKPKRAPKQKKVVEAVNSDSDSE 1522
Query: 624 WNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDKEDDLFAIAKDSQKKTQ 683
+ IP T R + + SG+ + +KTS K + KK +
Sbjct: 1523 FGIPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKTS--------------KTTSKKPK 1568
Query: 684 RVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGV 737
+ S + DVD S F + P S+P + ++ E SDEEE + +
Sbjct: 1569 KTSFDQDSDVDIFPSDFPTEPPSLPRTGRARK---EVKYFAESDEEEDDVDFAM 1619
Score = 40.8 bits (94), Expect = 0.009
Identities = 73/326 (22%), Positives = 119/326 (36%), Gaps = 53/326 (16%)
Query: 264 DSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDAMGRVDEEPTTLPSGEAKPRKTL 323
D K E D+E+ E P+ S A E + EE + L
Sbjct: 1333 DESKSESDLEETEPVVIPRDSLLRRAAAE-----RPKYTFDFSEEEDDDADDDDDDNNDL 1387
Query: 324 KEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEE-SDLF---- 378
+E K + +P ++ ++ F P D+D F G + K L D + ++ +LF
Sbjct: 1388 EELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKKSQDFGNLFSFPS 1447
Query: 379 -TEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSLKEPQKPEQPT 437
++ S+D A EE S+S + S L TD + +V + K KP T
Sbjct: 1448 YSQKSEDDSAKFDSNEEDSAS-------VFSPSFGLKQTDKVPSKTVAAKK--GKPSSDT 1498
Query: 438 PRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTADIFGDEEGDLFKEKAVA 497
K P + + + D D +F P KT + +G K++ +
Sbjct: 1499 VPKPKRAPKQKKVVEAVNSDSDSEF-----GIPKKTTTPKG--------KGRGAKKRKAS 1545
Query: 498 SPEATVSQTDENKARAEKKVTLSYSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASNLK 557
E ++ D N R K T +K K D++ D+F S +
Sbjct: 1546 GSE---NEGDYNPGRKTSKTT------------SKKPKKTSFDQDSDVDIFPSDFPTE-- 1588
Query: 558 GASLLP--GKLPTSVSLFDDEDEEDN 581
LP G+ V F + DEE++
Sbjct: 1589 -PPSLPRTGRARKEVKYFAESDEEED 1613
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 52.0 bits (123), Expect = 4e-06
Identities = 116/611 (18%), Positives = 196/611 (32%), Gaps = 124/611 (20%)
Query: 263 ADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDAMGRVDEEPTTLPSGEAKPRKT 322
A + D ED E + P A A R+ LP G+A + +
Sbjct: 78 AKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVG-------------LPPGKAAAKAS 124
Query: 323 LKEKKERRTPSDDEEDN---------------LFAPPK----------LTDEDFSPFGS- 356
E + DDEED APPK + ED P
Sbjct: 125 ESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQK 184
Query: 357 --------------------GGGLFSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESS 396
+ GK S ++ S++ +A A+ K+
Sbjct: 185 PKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVP 244
Query: 397 SSKPGKKIPAGAVSVFLGDTDVFGAASVPSLKEPQKP--EQPTPRKS---PYGPPP---- 447
+ K P A + + +S +E +KP +P P S P PPP
Sbjct: 245 KKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSL 304
Query: 448 ------------TGLFDDDDGDDDDDFFSAPHSKP------SKTRKVQSTADIFGDEEGD 489
+ +D D+ D S KP SK A + D
Sbjct: 305 GTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSD 364
Query: 490 LFKEKAVASPEATVSQTDENKARAEKKVTLSYSKNLKP--------------------SS 529
+ EA K + K + S +KP SS
Sbjct: 365 SSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSS 424
Query: 530 ETKTQKGLFSDEEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAK 589
++ + +E+ + + +++ + K A LP K S D + D+ +
Sbjct: 425 SSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSR-DSSSDSDSSSSEEEEE 483
Query: 590 KQTLSLQAQREEKAKASELSKKKASALLFSSDEEWNIPASQTHLASDSRSKGE------- 642
K + S ++ +K K ASA ++ + + + + + KG+
Sbjct: 484 KTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQA 543
Query: 643 PRDSGT--LQSQEAKAVKKTSLFEEDKEDDLFAIAKD-SQKKTQRVSLLFEDDVDSGGSL 699
P+ +GT L +Q KA K + EE+K+ ++K S KK ++ E + +
Sbjct: 544 PKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQAKKI 603
Query: 700 FGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKK-------VESAKESLK 752
P + P K ++ S + +E E ++++ S D K E A + LK
Sbjct: 604 KLQTPNTFPKRKKGEKRASSPFRRVREEEIEVDSRVADNSFDAKRGAAGDWGERANQVLK 663
Query: 753 FGRTDVAESEK 763
F + EK
Sbjct: 664 FTKGKSFRHEK 674
Score = 45.1 bits (105), Expect = 5e-04
Identities = 146/675 (21%), Positives = 231/675 (34%), Gaps = 145/675 (21%)
Query: 445 PPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTADIFGDEEGDLFKEKAVASPEATVS 504
P G D+ + + F+ + S DI+ F K+ PE +
Sbjct: 16 PLVLGFLRDNQLSEVANKFAKATGATQQDANASSLLDIYS------FWLKSAKVPERKLQ 69
Query: 505 QTDENKARAEKKVTLSYSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASNLKGASLLPG 564
+A+KK + S S++ SSE +EE+ + + ++A K L PG
Sbjct: 70 ANGPVAKKAKKKASSSDSED---SSE---------EEEEVQGPPAKKAAVPAKRVGLPPG 117
Query: 565 KLPTSVS-------LFDDEDEEDNLFGGTAAKKQTLSLQAQREEKAKASELSKKKASALL 617
K S DD+DEED KKQ +Q + +AKA++ KKA
Sbjct: 118 KAAAKASESSSSEESSDDDDEEDQ-------KKQ--PVQKGVKPQAKAAKAPPKKAK--- 165
Query: 618 FSSDEEWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDKEDDLFAIAKD 677
SSD + SDS S+ EP ++Q+ K T + A K
Sbjct: 166 -SSDSD-----------SDSSSEDEPP-----KNQKPKITPVT----------VKAQTKA 198
Query: 678 SQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGV 737
K + + S S S +S EEEK A
Sbjct: 199 PPKPARAAPKIANGKAASSSSSSSSSSSS------------------DDSEEEKAAATPK 240
Query: 738 KSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVK---------HSDLFSSSSPWD 788
K+V KK AK +K T +S + +E K +S + S+P
Sbjct: 241 KTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPP 300
Query: 789 K---GTKPRTKTV---------LSLFDEEEDKMEDQNIIQAPQKEVGKGCDPDAHPKSTG 836
K GT+P K V DE + E++ + P K V P
Sbjct: 301 KKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEK--KPPTKAVVSKATTKPPPAKKA 358
Query: 837 VFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQ 896
+ S + D P AGT K +P+V + + ++A QP+
Sbjct: 359 AESSSDSSDSDSSEDDEAPSKP--AGTTKNSSNKPAVTTKSPAVKP----AAAPKQPVGG 412
Query: 897 EKKRVVKKDHSVNSFKNQKHPESIQGSKEKGIWKPE-TPQANLAINPAALLPTAASQISE 955
+K + +K S +S + E + K KP+ T +A L++ PA P + S
Sbjct: 413 GQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSL-PAKQAPQGSRDSSS 471
Query: 956 VKPVLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKR 1015
+ S E +V P G + PA A +
Sbjct: 472 DSD-----SSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASA----------------K 510
Query: 1016 RPQTRAARRLAAQESSEAEDMSV-------PRGPIAQWADGAISPNGHRPQLRAASGEDS 1068
+ + ++ ++ +SSE E+ + P+ P A + NG A + E+
Sbjct: 511 KGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGK----AAKNSEEE 566
Query: 1069 TEEALAAAAAPWEGG 1083
EE AA + G
Sbjct: 567 EEEKKKAAVVVSKSG 581
Score = 35.8 bits (81), Expect = 0.28
Identities = 57/267 (21%), Positives = 103/267 (38%), Gaps = 27/267 (10%)
Query: 1026 AAQESSEAEDMSVPRGPIAQWADGAISP--NGHRPQLRAASGEDSTEEALAAAAAPWEGG 1083
++ +S E + + P+ + + A +P P +++S EDS+ + P +
Sbjct: 226 SSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNK 285
Query: 1084 P-----VPGVDTSPFAKSLGHSRGEADL-----FDSGDIFSTGTGSQSVERTKP--KAKI 1131
P VP P KSLG + + +S + S + S S E KP KA +
Sbjct: 286 PGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVV 345
Query: 1132 AENPANPPVGGKAKSPMFPALGEASSDDD--------LFQSAKPKPAKKTNP---FPLLE 1180
++ PP KA + SS+DD +++ KPA T P
Sbjct: 346 SKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAA 405
Query: 1181 DEDDLFTDQKVKKNETKSSSQQDVILTTQDIFEDDIFATEAIKPSQKTREK--EKTLESN 1238
+ + QK+ + SSS ++ ++++ + AT K + K K
Sbjct: 406 PKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQG 465
Query: 1239 LFDDNIDIFADLTVKPKEKSKKKVEAK 1265
D + D + + + +EK+ K K
Sbjct: 466 SRDSSSDSDSSSSEEEEEKTSKSAVKK 492
Score = 31.2 bits (69), Expect = 6.9
Identities = 34/135 (25%), Positives = 51/135 (37%), Gaps = 21/135 (15%)
Query: 1041 GPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAAAAPWEGGPVPGVDTSPFAKSLGHS 1100
GP+A+ A + + ++ EDS+EE P + VP AK +G
Sbjct: 72 GPVAKKA---------KKKASSSDSEDSSEEEEEVQGPPAKKAAVP-------AKRVGLP 115
Query: 1101 RGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANPPVGGKAKSPMFPALGEASSDDD 1160
G+A S S + E + K P V +AK+ P SSD D
Sbjct: 116 PGKAAAKASESSSSEESSDDDDEEDQKK-----QPVQKGVKPQAKAAKAPPKKAKSSDSD 170
Query: 1161 LFQSAKPKPAKKTNP 1175
S++ +P K P
Sbjct: 171 SDSSSEDEPPKNQKP 185
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 50.8 bits (120), Expect = 8e-06
Identities = 111/546 (20%), Positives = 207/546 (37%), Gaps = 92/546 (16%)
Query: 112 EAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFE-----QLDIKAGNSDSEEDDAN 166
E+++ +EKT+ Q E D P N + S+ E Q + S++D +
Sbjct: 143 ESKQIVEEKTKRQNEADKTPLKSSHENEQSKKSKSSSETNPESQNSKTVSKNCSQKDKKD 202
Query: 167 GRVELILEPKDLYI-DRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEK 225
+ + L+ + P L SK + + E+ SE S+ D +V ++
Sbjct: 203 SKNSKKTNTEFLHTKNNPKKDLKRSKTSNDP----ISEICSEN-SLNVDFLMLVGQSDD- 256
Query: 226 EEEESDEDFAHHSDNEQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSR 285
E D ++S N ++ + + + D + S+ E ED +D ++++ K+ +
Sbjct: 257 ESINFDAWLRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDS--KKVK 314
Query: 286 PTSFADELAARIKGDAMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPK 345
D+ +K D E T SG++K + +K +++ DD++ + P+
Sbjct: 315 KNVKKDDKKKDVKKDT------ESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPE 368
Query: 346 LTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSSSKPGKKIP 405
T D ES +A D + + K KKI
Sbjct: 369 ST------------------------DTESGDAKDARNDSRNLKKASKNDDKKKDAKKI- 403
Query: 406 AGAVSVFLGDTDVFGAASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSA 465
F D++ S KE QK E+ + S + D++ D D S
Sbjct: 404 -----TFSTDSE-----SELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDAD----SE 449
Query: 466 PHSKPSKTRKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSYSKNL 525
P K +K + D + D K+ A + E+T ++D E K +SK
Sbjct: 450 PKGDSKKGKKDEKKGK--KDSKKDDKKKDAKKNAESTEMESD-----LELKKDKKHSKE- 501
Query: 526 KPSSETKTQKGLFSDEEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLF-- 583
K S+ +K D E ++ F S + K ++ + G D + E++L+
Sbjct: 502 KKGSKKDIKKDARKDTESTDAEFDESSKTGFKTSTKIKG---------SDTESEESLYKP 552
Query: 584 ---------GGTAAKKQTLSLQAQR-----EEKAKASELSKKKASALLFSSDEEWNIPAS 629
GT+A + L+++R +K +E +K ++ + S E+ +PA
Sbjct: 553 GAKKKIDESDGTSANSKMEGLESKRGFRMSSKKTTFNEKGEKASTGRVPPSREKPPLPAC 612
Query: 630 QTHLAS 635
+ L S
Sbjct: 613 EPSLPS 618
Score = 38.9 bits (89), Expect = 0.033
Identities = 55/234 (23%), Positives = 93/234 (39%), Gaps = 28/234 (11%)
Query: 220 DTEEEKEEEESDEDFAHHS-DNEQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEEN 278
D+E E E +ES +D D++ + + +DEE D + DS+K ++D
Sbjct: 408 DSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKD------- 460
Query: 279 TRPKRSRPTSFADELAARIKGDAMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEED 338
K+ + S D+ K +A E T + S + + +K K KE++ D +
Sbjct: 461 --EKKGKKDSKKDDKKKDAKKNA------ESTEMES-DLELKKDKKHSKEKKGSKKDIKK 511
Query: 339 NLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEASQ---DRQAGASV--KE 393
+ + TD +F S G + K D + E L+ ++ D G S K
Sbjct: 512 DARKDTESTDAEFDE-SSKTGFKTSTKIKGSDTESEESLYKPGAKKKIDESDGTSANSKM 570
Query: 394 ESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSLKEPQKPEQPTPRKSPYGPPP 447
E SK G ++ + + F + VP P + + P P P P P
Sbjct: 571 EGLESKRGFRM-SSKKTTFNEKGEKASTGRVP----PSREKPPLPACEPSLPSP 619
Score = 38.5 bits (88), Expect = 0.043
Identities = 69/307 (22%), Positives = 125/307 (40%), Gaps = 36/307 (11%)
Query: 455 DGDDDDDFFSAPHSKPSKTRKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENKARAE 514
D + +D S K SK K D D++ D+ K+ E+T +++ ++K E
Sbjct: 297 DAESED---SKDAKKDSKKVKKNVKKD---DKKKDVKKDT-----ESTDAESGDSKD--E 343
Query: 515 KKVTLSYSKNLKPSSETK-TQKGLFSDEEDSEDLFSSQSAS-NLKGASLLPGKLPTSVSL 572
+K T K LK + K T+K S + +S D +++ S NLK AS K + +
Sbjct: 344 RKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKI 403
Query: 573 FDDEDEEDNLFGGTAAKKQ--------TLSLQAQREEKAKASELSKKKASALLFSSDEEW 624
D E L + K + T + ++ + ++ S+ K + DE+
Sbjct: 404 TFSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKK 463
Query: 625 NIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDKEDDLFAIAKDSQKKTQR 684
S+ D + K +++ + + + +KK ++K+ I KD++K T+
Sbjct: 464 GKKDSK----KDDKKKDAKKNAESTEMESDLELKKDKKHSKEKKGSKKDIKKDARKDTES 519
Query: 685 VSLLFEDDVDSG--------GSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLG 736
F++ +G GS S + P KKK S+ S E E++ G
Sbjct: 520 TDAEFDESSKTGFKTSTKIKGSDTESEESLYKPGAKKKIDESDGTS-ANSKMEGLESKRG 578
Query: 737 VKSVDKK 743
+ KK
Sbjct: 579 FRMSSKK 585
Score = 34.3 bits (77), Expect = 0.81
Identities = 62/309 (20%), Positives = 119/309 (38%), Gaps = 60/309 (19%)
Query: 639 SKGEPRDSGTLQSQEAKAVKKTS--LFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSG 696
+K + S +S+++K KK S + + K+DD KD +K T+ D +SG
Sbjct: 288 TKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDK---KKDVKKDTEST------DAESG 338
Query: 697 GSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRT 756
S ++K+T + L D+++K+ + +S D + AK++ R
Sbjct: 339 DS-----------KDERKDTKKDKKKLK-KDDKKKDTKKYPESTDTESGDAKDARNDSR- 385
Query: 757 DVAESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQ 816
++ ++ K + A++ FS+ S + +K K DE++DK + + +
Sbjct: 386 NLKKASKNDDKKKDAKKIT-----FSTDSESELESKESQK------DEKKDKKDSKTDNK 434
Query: 817 APQKEVGKGCDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSL 876
K + D D+ PK ++ K K +D D + T++
Sbjct: 435 KSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEM-------- 486
Query: 877 FGDDEDDDLFSSAKSQPLVQEKKRVVKKD--------------HSVNSFKNQKHPESIQG 922
+ D +L K + K+ +KKD S FK +
Sbjct: 487 ---ESDLELKKDKKHSKEKKGSKKDIKKDARKDTESTDAEFDESSKTGFKTSTKIKGSDT 543
Query: 923 SKEKGIWKP 931
E+ ++KP
Sbjct: 544 ESEESLYKP 552
>gi|239747798 PREDICTED: hypothetical protein XP_002348316 [Homo
sapiens]
Length = 399
Score = 50.1 bits (118), Expect = 1e-05
Identities = 66/290 (22%), Positives = 117/290 (40%), Gaps = 48/290 (16%)
Query: 492 KEKAVASPEATVSQTDENKARAEKKVTLSYSKNLK---PSSETKTQKGLFSDEEDSEDLF 548
K V+S + S+ +K + + L+ SS+ + +DEEDS
Sbjct: 106 KSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNI 165
Query: 549 SSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFG--GTAAKKQTLSLQAQREEKA--- 603
+++ K ++ K P + D+ED N+ K +T+S Q Q KA
Sbjct: 166 ATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTD 225
Query: 604 ----------------KASELSKKKASALLFSSDEEWNIPASQTHLASDSRSKGEPRDSG 647
K+ +S +K AL +SDE + ++ +R K + S
Sbjct: 226 EEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDE-------KDSFSNITREKKDGEISR 278
Query: 648 TLQSQEAKAVKKTSLFEEDKEDDLFAIA--KDSQKKTQRVS-------LLFEDDVDSGGS 698
T+ S++ +K TS D+ED + IA K+ +KT+RVS D+ DS
Sbjct: 279 TVTSEKPAGLKATS----DEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSDEKDS--- 331
Query: 699 LFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAK 748
F + + S+ PP L + +E+++ L + +K E ++
Sbjct: 332 -FSNITREKKDGETSRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSR 380
Score = 43.1 bits (100), Expect = 0.002
Identities = 84/406 (20%), Positives = 161/406 (39%), Gaps = 57/406 (14%)
Query: 528 SSETKTQKGLFSDEEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTA 587
SS+ + + SD++DS +++ ++ K P + D++D N+
Sbjct: 9 SSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIK 68
Query: 588 AKKQTLSLQAQREEKAKASELSKKKASAL-------------LFSSDEEWNIPASQTHLA 634
+Q+ ++ Q++ K + KKK S L SS ++ A+
Sbjct: 69 EGQQSGTVSPQKQSAWKV--IFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD 126
Query: 635 SDSRSKGEPRDS---GTLQSQEAKAVKKTSLFEEDKEDDLFAIAKDSQKKTQRVSLLFED 691
S E +D GT+ SQ+ A+K T+ D+ED + IA + +
Sbjct: 127 SALNIATEIKDGLQCGTVSSQKQPALKATT----DEEDSVSNIATEIK------------ 170
Query: 692 DVDSGGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKESL 751
D + G++ ++ T ++++V + E+ + + K ++S+
Sbjct: 171 DGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSV 230
Query: 752 KFGRTDVAESEKEGLLTRSAQETVK----HSDLFSSSSPWDK-GTKPRTKTV-----LSL 801
T++ + EK G ++ + +K D FS+ + K G RT T L
Sbjct: 231 SIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKA 290
Query: 802 FDEEEDKMEDQNIIQAPQKEVGKGCDPDAHPKSTGV--FQDEELLFSHKLQKDNDPDVDL 859
+EED + NI A KE G+ + K + DE+ FS+ ++ D +
Sbjct: 291 TSDEEDSV--LNI--ARGKEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSR 346
Query: 860 FAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEKKRVVKKD 905
++K L+ + DE+D + S A+ + EK R V +
Sbjct: 347 TVSSQKPPALKAT------SDEEDSVLSIAREEK-DGEKSRTVSSE 385
>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
precursor [Homo sapiens]
Length = 497
Score = 49.7 bits (117), Expect = 2e-05
Identities = 96/441 (21%), Positives = 164/441 (37%), Gaps = 60/441 (13%)
Query: 251 DEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDAMGRVDEEPT 310
D++EDD G D F D + +D +E + D + A + G+ + T
Sbjct: 87 DDDEDDSGDDTFGDDDSGPGP-KDRQEGGNSRLGSDEDSDDTIQASEESAPQGQDSAQDT 145
Query: 311 TLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDD 370
T S E + K E + + E ++E + GS G G DD
Sbjct: 146 TSESRELDNEDRVDSKPEGGDSTQESE---------SEEHWVGGGSDGESSHGDGSELDD 196
Query: 371 EDEESDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSLKEP 430
E +SD D ++ S + S + G K + +T G + +
Sbjct: 197 EGMQSD-------DPESIRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQL-----L 244
Query: 431 QKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTADIFGDEEGDL 490
+ P + RKS + ++DD + DD + K T S
Sbjct: 245 EHPSRKIFRKS-------RISEEDDRSELDDNNTMEEVKSDSTENSNS------------ 285
Query: 491 FKEKAVASPEATVSQTDENKARAEKKVTLSYSKNLK-PSSETKTQKGLFSDEEDSEDLFS 549
++ ++ P +++ +++ ++ S+N+ PSSE+ + L S E S
Sbjct: 286 -RDTGLSQPRR--DSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQEN------S 336
Query: 550 SQSASNLKGASLLPGKLPTSVSLFDDED----EEDNLFGGTAAKKQTLSLQAQRE--EKA 603
S+S + S PT+ + D ED EED+ + +K ++ QA E E
Sbjct: 337 SESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESL 396
Query: 604 KASELSKKKASALLFSSDEEWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTSLF 663
SE S + SS E +S S+ S E DS + S +K ++
Sbjct: 397 NFSEESPESPEDENSSSQEGLQSHSSSAESQSE-ESHSEEDDSDSQDSSRSKEDSNSTES 455
Query: 664 EEDKEDD--LFAIAKDSQKKT 682
+ E+D L I +S+K T
Sbjct: 456 KSSSEEDGQLKNIEIESRKLT 476
Score = 43.1 bits (100), Expect = 0.002
Identities = 76/411 (18%), Positives = 148/411 (36%), Gaps = 64/411 (15%)
Query: 202 GELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNQHTTQMSDEEEDDD---- 257
G S G G D+ D ++ ++ D+D + Q +++ +E+ DD
Sbjct: 73 GGFSRSTGKGGDDKDD--DEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDEDSDDTIQA 130
Query: 258 -------GCDLFADSEKEEEDIEDIEE-NTRPKRSRPTSFADELAARIKG---------- 299
G D D+ E ++++ + +++P+ T ++ + G
Sbjct: 131 SEESAPQGQDSAQDTTSESRELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGD 190
Query: 300 ----DAMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDN---------------- 339
D G ++P ++ S R K + + + E+ N
Sbjct: 191 GSELDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRK 250
Query: 340 LFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSSSK 399
+F ++++ED K D + + T SQ R+ +E S
Sbjct: 251 IFRKSRISEEDDRSELDDNNTMEEVKS--DSTENSNSRDTGLSQPRRDSKGDSQEDSKEN 308
Query: 400 PGKKIPAGAVSVFLGDTDVFGAASVPSLKEPQKPEQPTPRKSPYGPPPTGLF----DDDD 455
++ + +S + E Q E+ P PT + +D D
Sbjct: 309 LSQEESQNVDGPSSESSQEANLSSQENSSESQ--EEVVSESRGDNPDPTTSYVEDQEDSD 366
Query: 456 GDDDDDFFSAPHSKPSKTRKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEK 515
++D + HSK S++R+ Q+ ++ E F E++ SPE DEN + E
Sbjct: 367 SSEEDSSHTLSHSK-SESREEQADSE---SSESLNFSEESPESPE------DENSSSQEG 416
Query: 516 KVTLSYSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASNLKGASLLPGKL 566
S+S + + SE + SD +DS +++ K +S G+L
Sbjct: 417 --LQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQL 465
Score = 37.0 bits (84), Expect = 0.13
Identities = 83/412 (20%), Positives = 146/412 (35%), Gaps = 72/412 (17%)
Query: 356 SGGGLFSGGKGLFDDEDEESDLFTEASQDRQAGASVK--EESSSSKPGKKIPAGAVSVFL 413
+GG S GKG D +D+E D + D +G K +E +S+ G
Sbjct: 72 AGGFSRSTGKGGDDKDDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSD---------- 121
Query: 414 GDTDVFGAASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKT 473
D+D AS S + Q Q T +S + D++D S P S
Sbjct: 122 EDSDDTIQASEESAPQGQDSAQDTTSES------------RELDNEDRVDSKPEGGDSTQ 169
Query: 474 RKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSYSKNLKPSSETKT 533
+ G +G+ + + D R+E+ + S +K
Sbjct: 170 ESESEEHWVGGGSDGESSHGDGSELDDEGMQSDDPESIRSERGNSRMNSAGMK-----SK 224
Query: 534 QKGLFSDEEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAK---- 589
+ G S++ +++D SQ + P + S +ED+ L +
Sbjct: 225 ESGENSEQANTQDSGGSQLLEH-------PSRKIFRKSRISEEDDRSELDDNNTMEEVKS 277
Query: 590 --------KQTLSLQAQREEKAKASELSKKKASALLFSSDEEWNI--PASQTHLASDSRS 639
+ T Q +R+ K + E SK+ S +E N+ P+S++ ++ S
Sbjct: 278 DSTENSNSRDTGLSQPRRDSKGDSQEDSKEN-----LSQEESQNVDGPSSESSQEANLSS 332
Query: 640 KGEPRDSGTLQSQEAKA--VKKTSLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGG 697
+ +S E++ T+ + ED+ED + S + S E+ DS
Sbjct: 333 QENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSES 392
Query: 698 SLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKE 749
S + E E+P ++E +Q G++S ES E
Sbjct: 393 S----------ESLNFSEESPESP-----EDENSSSQEGLQSHSSSAESQSE 429
Score = 35.4 bits (80), Expect = 0.36
Identities = 42/186 (22%), Positives = 82/186 (44%), Gaps = 26/186 (13%)
Query: 157 NSDSEEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRG 216
N S+E+ + + E++ E + D P P + +QED SSEE S +
Sbjct: 329 NLSSQENSSESQEEVVSESRG---DNPDPT---TSYVEDQEDSD----SSEEDSSHTLSH 378
Query: 217 SIVDTEEEKEEEESDE--DFAHHS-DNEQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIE 273
S ++ EE+ + ES E +F+ S ++ ++++++ + + ++ EED
Sbjct: 379 SKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDS 438
Query: 274 DIEENTRPKRSRPTSFADELAARIKGDAMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPS 333
D ++++R K D + K + EE L + E + RK + + P
Sbjct: 439 DSQDSSRSKE-------DSNSTESKSSS-----EEDGQLKNIEIESRKLTVDAYHNK-PI 485
Query: 334 DDEEDN 339
D++DN
Sbjct: 486 GDQDDN 491
Score = 30.8 bits (68), Expect = 9.0
Identities = 36/166 (21%), Positives = 68/166 (40%), Gaps = 17/166 (10%)
Query: 102 EEVEEPVLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAG----- 156
E+ +E + + E++ + + +E +L + + + V +S + D
Sbjct: 303 EDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQ 362
Query: 157 -NSDSEEDDAN-----GRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGS 210
+SDS E+D++ + E E D L + S E E+ SS+EG
Sbjct: 363 EDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENS-----SSQEG- 416
Query: 211 VGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNQHTTQMSDEEEDD 256
+ S S EE EE D D S ++++ ++T+ E+D
Sbjct: 417 LQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEED 462
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 49.7 bits (117), Expect = 2e-05
Identities = 116/567 (20%), Positives = 203/567 (35%), Gaps = 119/567 (20%)
Query: 196 QEDVGLGELSSEEGSVGSD---RGSIVDTEEEKEEEESDE--------DFAHHSDNEQNQ 244
Q+D+ + E+ D R D+ EE E E+ S +E Q
Sbjct: 1484 QQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQ 1543
Query: 245 HTTQMSDEEED---DDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDA 301
+Q S EEED ++ AD + + ++ N + S T + + KG
Sbjct: 1544 EDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKI 1603
Query: 302 MGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLF-APPKLTDEDFSPFGSGGGL 360
T K ++ E RR DE+D F P+L + S +
Sbjct: 1604 TAGKHRRLTR------KSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRETKSQESEELV 1657
Query: 361 FSGGKGL----------------------------FDDEDE-ESDLFTEASQDRQAG-AS 390
+GG GL FD+E E E + T++ +DR G S
Sbjct: 1658 VTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDSPEDRSRGEGS 1717
Query: 391 VKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSLKEPQKPEQPTPRKSPYGPPPTGL 450
+SS PG +VS D+D S PS K+ + +Q R P+GP +
Sbjct: 1718 SSLHASSFTPGTS--PTSVSSLDEDSD-----SSPSHKKGESKQQRKARHRPHGPLLPTI 1770
Query: 451 FDDDDGDDDDDFFSAPHSKPSKTRKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENK 510
D S+ +++ ++ ++E E+ + S+ D+++
Sbjct: 1771 EDS-----------------SEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDE 1813
Query: 511 ARAEKK--------VTLSYSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASNLKGASLL 562
RA+++ LS ++ P+ E + + S +S S+ +G +
Sbjct: 1814 LRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSIESDPEGFEIS 1873
Query: 563 PGK---------LPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQREEKAKASELSKKKA 613
P K LPT+VSL+ DE+ + Q+E KA + +++
Sbjct: 1874 PEKIIEVQKVYKLPTAVSLYSPTDEQSIM---------------QKEGSQKALKSAEEMY 1918
Query: 614 SALLFSSDEEWNIPASQTHLASDSRSKGEPRDSGTLQSQ--EAKAVKKT-------SLFE 664
++ + + PA+ D + EP G L V+ T SL
Sbjct: 1919 EEMMHKTHKYKAFPAANER---DEVFEKEPLYGGMLIEDYIYESLVEDTYNGSVDGSLLT 1975
Query: 665 EDKEDDLFAIAKDSQKKTQRVSLLFED 691
+E++ F K ++K + ++ED
Sbjct: 1976 RQEEENGFMQQKGREQKIRLSEQIYED 2002
Score = 48.9 bits (115), Expect = 3e-05
Identities = 171/851 (20%), Positives = 303/851 (35%), Gaps = 195/851 (22%)
Query: 105 EEPVLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDD 164
+E +K EAEK EK +E ++ IP + D K S E+D
Sbjct: 1160 QEQEVKTEAEKVILEKVKETLSMEKIPPMVTT---------------DQKQEESKLEKDK 1204
Query: 165 ANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEE 224
A+ E +PLP KL E+E ++ SEE + +++ ++
Sbjct: 1205 ASALQE----------KKPLPE--EKKLIPEEE-----KIRSEE------KKPLLEEKKP 1241
Query: 225 KEEEESDEDFAHHSDNEQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRS 284
E++ A S E+ +H DL + E E +E PK
Sbjct: 1242 TPEDKKLLPEAKTSAPEEQKH--------------DLLKSQVQIAE--EKLEGRVAPKTV 1285
Query: 285 RPTSFADELAARIKGDAMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPP 344
+ + +++G G P +LP + K KT+KE+ + PP
Sbjct: 1286 QE---GKQPQTKMEGLPSGT----PQSLPKEDDKTTKTIKEQPQ--------------PP 1324
Query: 345 KLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSSSKPGKKI 404
D GK + ED++SD T +SQ ++ + + SS
Sbjct: 1325 CTAKPD---------QVEPGKEKTEKEDDKSD--TSSSQQPKSPQGLSDTGYSSD----- 1368
Query: 405 PAGAVSVFLGDTDVFGAASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFS 464
+S LG+ +PSL PT K GL D + S
Sbjct: 1369 ---GISSSLGE--------IPSLI-------PTDEKDIL----KGLKKDSFSQE-----S 1401
Query: 465 APHSKPSKTRKVQST--------ADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKK 516
+P S PS K++ST A DE+ + + SPE Q EK
Sbjct: 1402 SP-SSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQ--------EKT 1452
Query: 517 VTLSYSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDE 576
+LS + + S E + +E+ +D F S ++ + D
Sbjct: 1453 QSLSETLEITISEEE-----IKESQEERKDTFKKDSQQDIPSSK--------------DH 1493
Query: 577 DEEDNLFGGTAAKKQTLSLQAQREEKAKASELSKKKASALLFSSDEEWNIPASQTHLASD 636
E+ +++ + E + +K+ +++ SS +E+ D
Sbjct: 1494 KEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYK--------QED 1545
Query: 637 SRSKGEPRDSGTLQSQEAKAVKKTSLFEEDK--EDDLFAIAK--DSQKKTQRVSLLFEDD 692
S+ GE D Q E A + S E+D+ + L I+ +SQKK ++
Sbjct: 1546 SQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKK---------EE 1596
Query: 693 VDSGGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLK 752
G + + T+K T S +E+ + D + LK
Sbjct: 1597 TKGKGKITAGKHRRL---TRKSST---------SIDEDAGRRHSWHDEDDEAFDESPELK 1644
Query: 753 FGRTDVAESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQ 812
+ T ESE+ + K +L S+ + DK + ++ SL+ +EE ++E +
Sbjct: 1645 YRETKSQESEELVVTGGGGLRRFKTIELNSTIA--DKYSAESSQKKTSLYFDEEPELEME 1702
Query: 813 NIIQAPQKEVGKGCDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPS 872
++ +P+ H S + S D+ P ++ K
Sbjct: 1703 SLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHRP 1762
Query: 873 VGSLFGDDEDDDLFSSAKSQPLV---QEKKR-VVKKDHSVNSFKNQKHPESIQGSKEKGI 928
G L ED + + + QEK+R + ++ +S K++K + ++ + +
Sbjct: 1763 HGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQRRRE- 1821
Query: 929 WKPETPQANLA 939
+P+TP +NL+
Sbjct: 1822 -RPKTPPSNLS 1831
Score = 32.3 bits (72), Expect = 3.1
Identities = 58/338 (17%), Positives = 126/338 (37%), Gaps = 49/338 (14%)
Query: 211 VGSDRGSIVDTEEEKEEEESD--EDFAHHSDNEQNQHTTQMSDEEEDDDGCDLFADSEK- 267
VG + ++ EE+K++++ D + +Q + ++ E ++ F + EK
Sbjct: 3195 VGDESALLIVPEEDKQQQQLDLERELLELEKIKQQRFAEELEWERQE---IQRFREQEKI 3251
Query: 268 ----EEEDIEDIEENT--RPKRSRPTSFADELAARIKGDAMGRVDEEPTTLPSGEAKPRK 321
+ E+++ ++++ + + R F ++ + + + + + + + +
Sbjct: 3252 MVQKKLEELQSMKQHLLFQQEEERQAQFM------MRQETLAQQQLQLEQIQQLQQQLHQ 3305
Query: 322 TLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEA 381
L+E+K R+ + + + A P+ T E G L E S +
Sbjct: 3306 QLEEQKIRQIYQYNYDPSGTASPQTTTEQAILEGQYAAL------------EGSQFWATE 3353
Query: 382 SQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSLKEPQKPEQPTPRKS 441
A A V E S+ + + V+ ++ + S L + E+ P+K
Sbjct: 3354 DATTTASAVVAIEIPQSQGWYTVQSDGVTQYIAPPGILSTVSEIPLTDVVVKEEKQPKKR 3413
Query: 442 PYGPPPTGLFDD----------------DDGDDDDDFFSAPHSKPSKTRKVQSTADI--- 482
G G +DD D G DD + S S+ R+ + + D
Sbjct: 3414 SSGAKVRGQYDDMGENMTDDPRSFKKIVDSGVQTDDEDATDRSYVSRRRRTKKSVDTSVQ 3473
Query: 483 FGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLS 520
DE+ D + + +A V + ++ A+K LS
Sbjct: 3474 TDDEDQDEWDMPTRSRRKARVGKYGDSMTEADKTKPLS 3511
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 49.7 bits (117), Expect = 2e-05
Identities = 116/567 (20%), Positives = 203/567 (35%), Gaps = 119/567 (20%)
Query: 196 QEDVGLGELSSEEGSVGSD---RGSIVDTEEEKEEEESDE--------DFAHHSDNEQNQ 244
Q+D+ + E+ D R D+ EE E E+ S +E Q
Sbjct: 1484 QQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQ 1543
Query: 245 HTTQMSDEEED---DDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDA 301
+Q S EEED ++ AD + + ++ N + S T + + KG
Sbjct: 1544 EDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKI 1603
Query: 302 MGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLF-APPKLTDEDFSPFGSGGGL 360
T K ++ E RR DE+D F P+L + S +
Sbjct: 1604 TAGKHRRLTR------KSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRETKSQESEELV 1657
Query: 361 FSGGKGL----------------------------FDDEDE-ESDLFTEASQDRQAG-AS 390
+GG GL FD+E E E + T++ +DR G S
Sbjct: 1658 VTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDSPEDRSRGEGS 1717
Query: 391 VKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSLKEPQKPEQPTPRKSPYGPPPTGL 450
+SS PG +VS D+D S PS K+ + +Q R P+GP +
Sbjct: 1718 SSLHASSFTPGTS--PTSVSSLDEDSD-----SSPSHKKGESKQQRKARHRPHGPLLPTI 1770
Query: 451 FDDDDGDDDDDFFSAPHSKPSKTRKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENK 510
D S+ +++ ++ ++E E+ + S+ D+++
Sbjct: 1771 EDS-----------------SEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDE 1813
Query: 511 ARAEKK--------VTLSYSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASNLKGASLL 562
RA+++ LS ++ P+ E + + S +S S+ +G +
Sbjct: 1814 LRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSIESDPEGFEIS 1873
Query: 563 PGK---------LPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQREEKAKASELSKKKA 613
P K LPT+VSL+ DE+ + Q+E KA + +++
Sbjct: 1874 PEKIIEVQKVYKLPTAVSLYSPTDEQSIM---------------QKEGSQKALKSAEEMY 1918
Query: 614 SALLFSSDEEWNIPASQTHLASDSRSKGEPRDSGTLQSQ--EAKAVKKT-------SLFE 664
++ + + PA+ D + EP G L V+ T SL
Sbjct: 1919 EEMMHKTHKYKAFPAANER---DEVFEKEPLYGGMLIEDYIYESLVEDTYNGSVDGSLLT 1975
Query: 665 EDKEDDLFAIAKDSQKKTQRVSLLFED 691
+E++ F K ++K + ++ED
Sbjct: 1976 RQEEENGFMQQKGREQKIRLSEQIYED 2002
Score = 48.9 bits (115), Expect = 3e-05
Identities = 171/851 (20%), Positives = 303/851 (35%), Gaps = 195/851 (22%)
Query: 105 EEPVLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDD 164
+E +K EAEK EK +E ++ IP + D K S E+D
Sbjct: 1160 QEQEVKTEAEKVILEKVKETLSMEKIPPMVTT---------------DQKQEESKLEKDK 1204
Query: 165 ANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEE 224
A+ E +PLP KL E+E ++ SEE + +++ ++
Sbjct: 1205 ASALQE----------KKPLPE--EKKLIPEEE-----KIRSEE------KKPLLEEKKP 1241
Query: 225 KEEEESDEDFAHHSDNEQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRS 284
E++ A S E+ +H DL + E E +E PK
Sbjct: 1242 TPEDKKLLPEAKTSAPEEQKH--------------DLLKSQVQIAE--EKLEGRVAPKTV 1285
Query: 285 RPTSFADELAARIKGDAMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPP 344
+ + +++G G P +LP + K KT+KE+ + PP
Sbjct: 1286 QE---GKQPQTKMEGLPSGT----PQSLPKEDDKTTKTIKEQPQ--------------PP 1324
Query: 345 KLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSSSKPGKKI 404
D GK + ED++SD T +SQ ++ + + SS
Sbjct: 1325 CTAKPD---------QVEPGKEKTEKEDDKSD--TSSSQQPKSPQGLSDTGYSSD----- 1368
Query: 405 PAGAVSVFLGDTDVFGAASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFS 464
+S LG+ +PSL PT K GL D + S
Sbjct: 1369 ---GISSSLGE--------IPSLI-------PTDEKDIL----KGLKKDSFSQE-----S 1401
Query: 465 APHSKPSKTRKVQST--------ADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKK 516
+P S PS K++ST A DE+ + + SPE Q EK
Sbjct: 1402 SP-SSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQ--------EKT 1452
Query: 517 VTLSYSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDE 576
+LS + + S E + +E+ +D F S ++ + D
Sbjct: 1453 QSLSETLEITISEEE-----IKESQEERKDTFKKDSQQDIPSSK--------------DH 1493
Query: 577 DEEDNLFGGTAAKKQTLSLQAQREEKAKASELSKKKASALLFSSDEEWNIPASQTHLASD 636
E+ +++ + E + +K+ +++ SS +E+ D
Sbjct: 1494 KEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYK--------QED 1545
Query: 637 SRSKGEPRDSGTLQSQEAKAVKKTSLFEEDK--EDDLFAIAK--DSQKKTQRVSLLFEDD 692
S+ GE D Q E A + S E+D+ + L I+ +SQKK ++
Sbjct: 1546 SQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKK---------EE 1596
Query: 693 VDSGGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLK 752
G + + T+K T S +E+ + D + LK
Sbjct: 1597 TKGKGKITAGKHRRL---TRKSST---------SIDEDAGRRHSWHDEDDEAFDESPELK 1644
Query: 753 FGRTDVAESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQ 812
+ T ESE+ + K +L S+ + DK + ++ SL+ +EE ++E +
Sbjct: 1645 YRETKSQESEELVVTGGGGLRRFKTIELNSTIA--DKYSAESSQKKTSLYFDEEPELEME 1702
Query: 813 NIIQAPQKEVGKGCDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPS 872
++ +P+ H S + S D+ P ++ K
Sbjct: 1703 SLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHRP 1762
Query: 873 VGSLFGDDEDDDLFSSAKSQPLV---QEKKR-VVKKDHSVNSFKNQKHPESIQGSKEKGI 928
G L ED + + + QEK+R + ++ +S K++K + ++ + +
Sbjct: 1763 HGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQRRRE- 1821
Query: 929 WKPETPQANLA 939
+P+TP +NL+
Sbjct: 1822 -RPKTPPSNLS 1831
Score = 32.3 bits (72), Expect = 3.1
Identities = 58/338 (17%), Positives = 126/338 (37%), Gaps = 49/338 (14%)
Query: 211 VGSDRGSIVDTEEEKEEEESD--EDFAHHSDNEQNQHTTQMSDEEEDDDGCDLFADSEK- 267
VG + ++ EE+K++++ D + +Q + ++ E ++ F + EK
Sbjct: 3195 VGDESALLIVPEEDKQQQQLDLERELLELEKIKQQRFAEELEWERQE---IQRFREQEKI 3251
Query: 268 ----EEEDIEDIEENT--RPKRSRPTSFADELAARIKGDAMGRVDEEPTTLPSGEAKPRK 321
+ E+++ ++++ + + R F ++ + + + + + + + +
Sbjct: 3252 MVQKKLEELQSMKQHLLFQQEEERQAQFM------MRQETLAQQQLQLEQIQQLQQQLHQ 3305
Query: 322 TLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEA 381
L+E+K R+ + + + A P+ T E G L E S +
Sbjct: 3306 QLEEQKIRQIYQYNYDPSGTASPQTTTEQAILEGQYAAL------------EGSQFWATE 3353
Query: 382 SQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSLKEPQKPEQPTPRKS 441
A A V E S+ + + V+ ++ + S L + E+ P+K
Sbjct: 3354 DATTTASAVVAIEIPQSQGWYTVQSDGVTQYIAPPGILSTVSEIPLTDVVVKEEKQPKKR 3413
Query: 442 PYGPPPTGLFDD----------------DDGDDDDDFFSAPHSKPSKTRKVQSTADI--- 482
G G +DD D G DD + S S+ R+ + + D
Sbjct: 3414 SSGAKVRGQYDDMGENMTDDPRSFKKIVDSGVQTDDEDATDRSYVSRRRRTKKSVDTSVQ 3473
Query: 483 FGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLS 520
DE+ D + + +A V + ++ A+K LS
Sbjct: 3474 TDDEDQDEWDMPTRSRRKARVGKYGDSMTEADKTKPLS 3511
>gi|145199237 transcription elongation factor B polypeptide 3
binding protein 1 [Homo sapiens]
Length = 1221
Score = 49.7 bits (117), Expect = 2e-05
Identities = 97/451 (21%), Positives = 162/451 (35%), Gaps = 78/451 (17%)
Query: 372 DEESDLFTEASQDRQAGASVKEESSSSKPG------------KKI--PAGAVSVFLGDTD 417
D E D + S + AS ++E ++ +P KK+ P G+ D++
Sbjct: 231 DLEYDPLSNYSARHLSRASSRDERAAKRPRGSRGSEPYTPAPKKLCDPFGSCDARFSDSE 290
Query: 418 VFGAASVPSLKEPQKPEQPTPRKSPY----GPPPT--GLFDDDDG---------DDDDDF 462
AA+VP EP P R P G PP+ GL + G D
Sbjct: 291 D-EAATVPG-NEPTTASTPKARADPEIKATGQPPSKEGLEAEGGGLRETKETAVQCDVGD 348
Query: 463 FSAPHSKPSKTRKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKK-----V 517
P +KP+ +VQS+ D +EG K+K A P + + K + + K V
Sbjct: 349 LQPPPAKPASPAQVQSSQDGGCPKEGKPKKKKTGAPPAPSCKDGAQGKDKTKDKGRGRPV 408
Query: 518 TLSYSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDED 577
+ P + + +K + + ++ A++ KG P + P+ S
Sbjct: 409 EKPRADKKGPQASSPRRKAERPEGTKKKPSSATPVATSGKGRPDRPARRPSPTS------ 462
Query: 578 EEDNLFGGTAAKKQTLSLQAQREEKAKASELSKKKASALLFSSDEEWNIPASQTHLASDS 637
D+ + L L ++ KA + +L ++KA +L
Sbjct: 463 -GDSRPAAGRGPPRPLQLPDRKSTKAPSGKLVERKARSL--------------------- 500
Query: 638 RSKGEPRDSGTLQSQEAKAVKKTSLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGG 697
+G +D+ L+ +A+ LF ++ ED+ S + SL + D DS
Sbjct: 501 -DEGASQDAPKLKK---RALSHADLFGDESEDEAAGPGVPSVWPSALPSLSSDSDSDSDS 556
Query: 698 SLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGV--------KSVDKKVESAKE 749
SL G P PP K P S + G K VD + +E
Sbjct: 557 SL-GFPEAQGPPKRLKASPPPSPAPSSSSSSSSSTSSAGADVDYSALEKEVDFDSDPMEE 615
Query: 750 SLK-FGRTDVAESEKEGLLTRSAQETVKHSD 779
L+ F + ++E G L R + K +
Sbjct: 616 CLRIFNESTSVKTEDRGRLARQPPKEEKSEE 646
>gi|217035154 RCSD domain containing 1 [Homo sapiens]
Length = 416
Score = 49.3 bits (116), Expect = 2e-05
Identities = 50/164 (30%), Positives = 69/164 (42%), Gaps = 12/164 (7%)
Query: 913 NQKHPESIQGSKEKGIWKPETPQANLAINPAALLPTAASQISEVKPVLPELAFPSSEHRR 972
N HP + I E QANL +PAALLP A+ + +K ++ P S
Sbjct: 71 NASHPPKFKVKSSPLI---EKLQANLTFDPAALLPGASPKSPGLKAMVSPFHSPPSTPS- 126
Query: 973 SHGLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQTRAARRLAAQESSE 1032
S G+ S P + E VSFD P + L NK R + KRRP +R RR S+
Sbjct: 127 SPGVRSRP--SEAEEVPVSFDQPPEGSHLPCYNKVRTRGSIKRRPPSRRFRR----SQSD 180
Query: 1033 AEDMSVPRGPIAQWADGAISPNGHR--PQLRAASGEDSTEEALA 1074
++ R + +GA +G P A G + E A
Sbjct: 181 CGELGDFRAVESSQQNGAKEEDGDEVLPSKSKAPGSPLSSEGAA 224
>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
Length = 709
Score = 48.9 bits (115), Expect = 3e-05
Identities = 37/139 (26%), Positives = 65/139 (46%), Gaps = 8/139 (5%)
Query: 196 QEDVGLGELSS--EEGSVGS--DRGSIVDTEEEKEEEESDEDFAHHSDNEQNQHTTQMSD 251
+E+V E S E GS GS ++G+ + EEE EE+ +ED D E+++ + +
Sbjct: 171 KEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGE 230
Query: 252 EEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDAMGRVDEEPTT 311
EEE+++ + E+EEE+ E+ E++ R ++ + A G +
Sbjct: 231 EEEEEEE----EEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVR 286
Query: 312 LPSGEAKPRKTLKEKKERR 330
SG + KE+K R
Sbjct: 287 SGSGTDGSDEKKKERKRAR 305
Score = 34.3 bits (77), Expect = 0.81
Identities = 21/83 (25%), Positives = 39/83 (46%), Gaps = 5/83 (6%)
Query: 195 EQEDVGLGELSSEEGSVGSD--RGSIVDTEEEKEEEESDEDFAHHSDNEQNQHTTQMSDE 252
E E+ G+ E E+ V D VD + E+EEEE +E+ + E+ + + +
Sbjct: 199 ENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEE---EEEEEEEEEEYEQDER 255
Query: 253 EEDDDGCDLFADSEKEEEDIEDI 275
++ ++G D SE + E +
Sbjct: 256 DQKEEGNDYDTRSEASDSGSESV 278
Score = 33.9 bits (76), Expect = 1.1
Identities = 21/73 (28%), Positives = 36/73 (49%), Gaps = 2/73 (2%)
Query: 206 SEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNQHTTQMSDEEEDDDGCDLFADS 265
SE + DR + ++ KEE S+E + H Q ++ E +++G + D
Sbjct: 152 SERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVE--EDV 209
Query: 266 EKEEEDIEDIEEN 278
E++EE ED EE+
Sbjct: 210 EEDEEVEEDAEED 222
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.306 0.126 0.347
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 55,391,667
Number of Sequences: 37866
Number of extensions: 3006447
Number of successful extensions: 20730
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 159
Number of HSP's successfully gapped in prelim test: 713
Number of HSP's that attempted gapping in prelim test: 12523
Number of HSP's gapped (non-prelim): 5122
length of query: 1318
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1204
effective length of database: 13,930,794
effective search space: 16772675976
effective search space used: 16772675976
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.