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Search of human proteins with 59710113
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|59710113 Rho GTPase activating protein 28 isoform a [Homo
sapiens]
(570 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|59710113 Rho GTPase activating protein 28 isoform a [Homo sap... 1123 0.0
gi|59710111 Rho GTPase activating protein 28 isoform b [Homo sap... 1013 0.0
gi|39932589 Rho GTPase activating protein 18 [Homo sapiens] 385 e-107
gi|239757488 PREDICTED: chromosome 20 open reading frame 95 [Hom... 302 6e-82
gi|239752003 PREDICTED: chromosome 20 open reading frame 95 [Hom... 302 6e-82
gi|239746488 PREDICTED: Rho GTPase-activating protein 18-like [H... 302 6e-82
gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens] 91 4e-18
gi|56119110 family with sequence similarity 13, member A1 isofor... 90 6e-18
gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens] 88 2e-17
gi|188497642 ARHGAP15 [Homo sapiens] 84 3e-16
gi|229094128 active breakpoint cluster region-related protein i... 84 5e-16
gi|33188433 deleted in liver cancer 1 isoform 1 [Homo sapiens] 84 5e-16
gi|33188437 deleted in liver cancer 1 isoform 2 [Homo sapiens] 84 5e-16
gi|38679957 active breakpoint cluster region-related protein is... 84 5e-16
gi|38679954 active breakpoint cluster region-related protein is... 84 5e-16
gi|26986534 Rho GTPase activating protein 12 [Homo sapiens] 80 5e-15
gi|41281907 StAR-related lipid transfer (START) domain containin... 80 7e-15
gi|16445031 StAR-related lipid transfer (START) domain containin... 80 7e-15
gi|41281898 StAR-related lipid transfer (START) domain containin... 80 7e-15
gi|226693398 Rho GTPase activating protein 27 isoform b [Homo sa... 79 1e-14
gi|40548322 Rho GTPase activating protein 27 isoform a [Homo sap... 79 1e-14
gi|7382480 Rho GTPase activating protein 6 isoform 4 [Homo sapiens] 76 7e-14
gi|95091988 Rho GTPase activating protein 6 isoform 3 [Homo sapi... 76 7e-14
gi|95091875 Rho GTPase activating protein 6 isoform 1 [Homo sapi... 76 7e-14
gi|5803145 ralA binding protein 1 [Homo sapiens] 76 9e-14
gi|215820652 StAR-related lipid transfer (START) domain containi... 76 9e-14
gi|215820650 StAR-related lipid transfer (START) domain containi... 76 9e-14
gi|31543659 StAR-related lipid transfer (START) domain containin... 76 9e-14
gi|150417981 glucocorticoid receptor DNA binding factor 1 [Homo ... 73 6e-13
gi|156119615 myosin IXA [Homo sapiens] 72 2e-12
>gi|59710113 Rho GTPase activating protein 28 isoform a [Homo
sapiens]
Length = 570
Score = 1124 bits (2906), Expect = 0.0
Identities = 570/570 (100%), Positives = 570/570 (100%)
Query: 1 MRKKDKQSIRDVRDIFGVSESPPRDTCGNHTNQLDGTKEERELPRVIKTSGSMPDDASLN 60
MRKKDKQSIRDVRDIFGVSESPPRDTCGNHTNQLDGTKEERELPRVIKTSGSMPDDASLN
Sbjct: 1 MRKKDKQSIRDVRDIFGVSESPPRDTCGNHTNQLDGTKEERELPRVIKTSGSMPDDASLN 60
Query: 61 STTLSDASQDKEGSFAVPRSDSVAILETIPVLPVHSNGSPEPGQPVQNAISDDDFLEKNI 120
STTLSDASQDKEGSFAVPRSDSVAILETIPVLPVHSNGSPEPGQPVQNAISDDDFLEKNI
Sbjct: 61 STTLSDASQDKEGSFAVPRSDSVAILETIPVLPVHSNGSPEPGQPVQNAISDDDFLEKNI 120
Query: 121 PPEAEELSFEVSYSEMVTEALKRNKLKKSEIKKEDYVLTKFNVQKTRFGLTEAGDLSAED 180
PPEAEELSFEVSYSEMVTEALKRNKLKKSEIKKEDYVLTKFNVQKTRFGLTEAGDLSAED
Sbjct: 121 PPEAEELSFEVSYSEMVTEALKRNKLKKSEIKKEDYVLTKFNVQKTRFGLTEAGDLSAED 180
Query: 181 MKKIRHLSLIELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVP 240
MKKIRHLSLIELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVP
Sbjct: 181 MKKIRHLSLIELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVP 240
Query: 241 LVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAAVML 300
LVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAAVML
Sbjct: 241 LVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAAVML 300
Query: 301 KAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFN 360
KAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFN
Sbjct: 301 KAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFN 360
Query: 361 KVIANESKNRMSLWNISTVMAPNLFFSRSKHSDYEELLLANTAAHIIRLMLKYQKILWKV 420
KVIANESKNRMSLWNISTVMAPNLFFSRSKHSDYEELLLANTAAHIIRLMLKYQKILWKV
Sbjct: 361 KVIANESKNRMSLWNISTVMAPNLFFSRSKHSDYEELLLANTAAHIIRLMLKYQKILWKV 420
Query: 421 PSFLITQVRRMNEATMLLKKQLPSVRKLLRRKTLERETASPKTSKVLQKSPSARRMSDVP 480
PSFLITQVRRMNEATMLLKKQLPSVRKLLRRKTLERETASPKTSKVLQKSPSARRMSDVP
Sbjct: 421 PSFLITQVRRMNEATMLLKKQLPSVRKLLRRKTLERETASPKTSKVLQKSPSARRMSDVP 480
Query: 481 EGVIRVHAPLLSKVSMAIQLNNQTKAKDILAKFQYENSHGSSECIKIQNQRLYEIGGNIG 540
EGVIRVHAPLLSKVSMAIQLNNQTKAKDILAKFQYENSHGSSECIKIQNQRLYEIGGNIG
Sbjct: 481 EGVIRVHAPLLSKVSMAIQLNNQTKAKDILAKFQYENSHGSSECIKIQNQRLYEIGGNIG 540
Query: 541 EHCLDPDAYILDVYRINPQAEWVIKPQQSS 570
EHCLDPDAYILDVYRINPQAEWVIKPQQSS
Sbjct: 541 EHCLDPDAYILDVYRINPQAEWVIKPQQSS 570
>gi|59710111 Rho GTPase activating protein 28 isoform b [Homo
sapiens]
Length = 563
Score = 1013 bits (2618), Expect = 0.0
Identities = 517/517 (100%), Positives = 517/517 (100%)
Query: 1 MRKKDKQSIRDVRDIFGVSESPPRDTCGNHTNQLDGTKEERELPRVIKTSGSMPDDASLN 60
MRKKDKQSIRDVRDIFGVSESPPRDTCGNHTNQLDGTKEERELPRVIKTSGSMPDDASLN
Sbjct: 1 MRKKDKQSIRDVRDIFGVSESPPRDTCGNHTNQLDGTKEERELPRVIKTSGSMPDDASLN 60
Query: 61 STTLSDASQDKEGSFAVPRSDSVAILETIPVLPVHSNGSPEPGQPVQNAISDDDFLEKNI 120
STTLSDASQDKEGSFAVPRSDSVAILETIPVLPVHSNGSPEPGQPVQNAISDDDFLEKNI
Sbjct: 61 STTLSDASQDKEGSFAVPRSDSVAILETIPVLPVHSNGSPEPGQPVQNAISDDDFLEKNI 120
Query: 121 PPEAEELSFEVSYSEMVTEALKRNKLKKSEIKKEDYVLTKFNVQKTRFGLTEAGDLSAED 180
PPEAEELSFEVSYSEMVTEALKRNKLKKSEIKKEDYVLTKFNVQKTRFGLTEAGDLSAED
Sbjct: 121 PPEAEELSFEVSYSEMVTEALKRNKLKKSEIKKEDYVLTKFNVQKTRFGLTEAGDLSAED 180
Query: 181 MKKIRHLSLIELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVP 240
MKKIRHLSLIELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVP
Sbjct: 181 MKKIRHLSLIELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVP 240
Query: 241 LVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAAVML 300
LVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAAVML
Sbjct: 241 LVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAAVML 300
Query: 301 KAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFN 360
KAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFN
Sbjct: 301 KAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFN 360
Query: 361 KVIANESKNRMSLWNISTVMAPNLFFSRSKHSDYEELLLANTAAHIIRLMLKYQKILWKV 420
KVIANESKNRMSLWNISTVMAPNLFFSRSKHSDYEELLLANTAAHIIRLMLKYQKILWKV
Sbjct: 361 KVIANESKNRMSLWNISTVMAPNLFFSRSKHSDYEELLLANTAAHIIRLMLKYQKILWKV 420
Query: 421 PSFLITQVRRMNEATMLLKKQLPSVRKLLRRKTLERETASPKTSKVLQKSPSARRMSDVP 480
PSFLITQVRRMNEATMLLKKQLPSVRKLLRRKTLERETASPKTSKVLQKSPSARRMSDVP
Sbjct: 421 PSFLITQVRRMNEATMLLKKQLPSVRKLLRRKTLERETASPKTSKVLQKSPSARRMSDVP 480
Query: 481 EGVIRVHAPLLSKVSMAIQLNNQTKAKDILAKFQYEN 517
EGVIRVHAPLLSKVSMAIQLNNQTKAKDILAKFQYEN
Sbjct: 481 EGVIRVHAPLLSKVSMAIQLNNQTKAKDILAKFQYEN 517
>gi|39932589 Rho GTPase activating protein 18 [Homo sapiens]
Length = 663
Score = 385 bits (989), Expect = e-107
Identities = 204/457 (44%), Positives = 295/457 (64%), Gaps = 20/457 (4%)
Query: 117 EKNIPPEAE-----ELSFEVSYSEMVTEALKRNKLKKSEIKKEDYVLTKFNVQKTRFGLT 171
EK IPPE +++ EVS++E + +K K + K +D L F + K + G T
Sbjct: 215 EKLIPPEETPAPETDINLEVSFAEQALNQKESSKEKIQKSKGDDATLPSFRLPKDKTGTT 274
Query: 172 EAGDLSAEDMKKIRHLSLIELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDR 231
GDL+ +DMKK+ HL+LIELTA +D GI+LK+ K K+K +D+G+F VPLT LL+ D+
Sbjct: 275 RIGDLAPQDMKKVCHLALIELTALYDVLGIELKQQKAVKIKTKDSGLFCVPLTALLEQDQ 334
Query: 232 KKDPGVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKM 291
+K PG+++PL+ QK ++EE GLE+EG+ R+ G ++K +EL+AKF F W+ +
Sbjct: 335 RKVPGMRIPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESV 394
Query: 292 CHREAAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDA 351
+AA +LK F RELP L VEY+ AF ++ P K Q QAL+L+V+ LPDANRD
Sbjct: 395 KQHDAASLLKLFIRELPQPLLSVEYLKAF-QAVQNLPTKKQQLQALNLLVILLPDANRDT 453
Query: 352 AQALMTFFNKVIANESKNRMSLWNISTVMAPNLFFSRS---KHSDYEELLLANTAAHIIR 408
+AL+ F +VI N+ KN+M++ N++ VMAPNLF + K S+ E ++A A+ +
Sbjct: 454 LKALLEFLQRVIDNKEKNKMTVMNVAMVMAPNLFMCHALGLKSSEQREFVMAAGTANTMH 513
Query: 409 LMLKYQKILWKVPSFLITQVRRMNEATMLLKKQLPSVRKLLRRKTLERETASPKTSKVLQ 468
L++KYQK+LW +P F++ QVR+ N T KK +++KLL++ +RE +
Sbjct: 514 LLIKYQKLLWTIPKFIVNQVRKQN--TENHKKDKRAMKKLLKKMAYDREK--------YE 563
Query: 469 KSPSARRMSDVPEGVIRVHAPLLSKVSMAIQLNNQTKAKDILAKFQYENSHGSSECIKIQ 528
K + +DVP+GVIRV AP LSKVSMAIQL + KA D+LA+F + S G ++ +K
Sbjct: 564 KQDKSTNDADVPQGVIRVQAPHLSKVSMAIQLTEELKASDVLARFLSQES-GVAQTLKKG 622
Query: 529 NQRLYEIGGNIGEHCLDPDAYILDVYRINPQAEWVIK 565
LYEIGGNIGE CLD D Y+ D+Y++NP AEWVIK
Sbjct: 623 EVFLYEIGGNIGERCLDDDTYMKDLYQLNPNAEWVIK 659
>gi|239757488 PREDICTED: chromosome 20 open reading frame 95 [Homo
sapiens]
Length = 622
Score = 302 bits (773), Expect = 6e-82
Identities = 181/462 (39%), Positives = 265/462 (57%), Gaps = 37/462 (8%)
Query: 125 EELSFEVSYSEMVTEALKRNKLKKSEIKKEDYV-LTKFNVQKTRFGLTEAGDLSAEDMKK 183
E + + +YSE L+R++ + L KF V K R G+T GDLS +DM+K
Sbjct: 173 EAFNMDSAYSEQAAVLLQRSRPSRGGTSAWGKCSLPKFTVPKGRLGVTRIGDLSLQDMRK 232
Query: 184 IRHLSLIELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVPLVL 243
+ L+LIELTA D G+ LKR+K K K + +FGVPL LL+ D K P +VPLVL
Sbjct: 233 VPSLALIELTALCDILGLDLKRSKAGKWKAAETRLFGVPLDSLLEADHKVLPSTQVPLVL 292
Query: 244 QKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAAVMLKAF 303
Q +E+ GL+ EGI R+ G A+VK ++L+ F A F WD++ H +A+ +LK F
Sbjct: 293 QALLSCLEKRGLDMEGILRVPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDASDLLKRF 352
Query: 304 FRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFNKVI 363
R+LPT L EY+PAF +++ P++K + Q LHL+++ LP+ NR+A +AL+ F KV+
Sbjct: 353 IRKLPTPLLTAEYLPAF-AVVPNIPNLKQRLQVLHLLILILPEPNRNALKALLEFLRKVV 411
Query: 364 ANESKNRMSLWNISTVMAPNLFFSRS---KHSDYEELLLANTAAHIIRLMLKYQKILWKV 420
A E N+M+L N+STVMAPNLF + K +E LA AA ++++M+ YQ +LW V
Sbjct: 412 AREQHNKMTLRNVSTVMAPNLFLHQGRPPKLPKGKEKQLAEGAAEVVQIMVHYQDLLWTV 471
Query: 421 PSFLITQVRRMNEATMLLKKQL--PSVRKLLRRKTLERETASPKTSKVLQKSPSARRMSD 478
SFL+ QVR++N+++ + QL ++ LRR +R+ K L+ +P +
Sbjct: 472 ASFLVAQVRKLNDSSS-RRPQLCDAGLKTWLRRMHADRD----KAGDGLEATPKVAK--- 523
Query: 479 VPEGVIRVHAPLLSKVSMAIQLNNQTKAKDILAKFQYENSHGSS---------------E 523
I+V P+ K + + L TK +L +F S GS
Sbjct: 524 -----IQVVWPI--KDPLKVPLTPSTKVAHVLRQFTEHLSPGSKGQEDSEDMDSLLLHHR 576
Query: 524 CIKIQNQRLYEIGGNIGEHCLDPDAYILDVYRINPQAEWVIK 565
++ N LYE+GGNI EH LDPDAY+LD+YR NP EWV+K
Sbjct: 577 SMESANILLYEVGGNINEHRLDPDAYLLDLYRANPHGEWVLK 618
>gi|239752003 PREDICTED: chromosome 20 open reading frame 95 [Homo
sapiens]
Length = 622
Score = 302 bits (773), Expect = 6e-82
Identities = 181/462 (39%), Positives = 265/462 (57%), Gaps = 37/462 (8%)
Query: 125 EELSFEVSYSEMVTEALKRNKLKKSEIKKEDYV-LTKFNVQKTRFGLTEAGDLSAEDMKK 183
E + + +YSE L+R++ + L KF V K R G+T GDLS +DM+K
Sbjct: 173 EAFNMDSAYSEQAAVLLQRSRPSRGGTSAWGKCSLPKFTVPKGRLGVTRIGDLSLQDMRK 232
Query: 184 IRHLSLIELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVPLVL 243
+ L+LIELTA D G+ LKR+K K K + +FGVPL LL+ D K P +VPLVL
Sbjct: 233 VPSLALIELTALCDILGLDLKRSKAGKWKAAETRLFGVPLDSLLEADHKVLPSTQVPLVL 292
Query: 244 QKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAAVMLKAF 303
Q +E+ GL+ EGI R+ G A+VK ++L+ F A F WD++ H +A+ +LK F
Sbjct: 293 QALLSCLEKRGLDMEGILRVPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDASDLLKRF 352
Query: 304 FRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFNKVI 363
R+LPT L EY+PAF +++ P++K + Q LHL+++ LP+ NR+A +AL+ F KV+
Sbjct: 353 IRKLPTPLLTAEYLPAF-AVVPNIPNLKQRLQVLHLLILILPEPNRNALKALLEFLRKVV 411
Query: 364 ANESKNRMSLWNISTVMAPNLFFSRS---KHSDYEELLLANTAAHIIRLMLKYQKILWKV 420
A E N+M+L N+STVMAPNLF + K +E LA AA ++++M+ YQ +LW V
Sbjct: 412 AREQHNKMTLRNVSTVMAPNLFLHQGRPPKLPKGKEKQLAEGAAEVVQIMVHYQDLLWTV 471
Query: 421 PSFLITQVRRMNEATMLLKKQL--PSVRKLLRRKTLERETASPKTSKVLQKSPSARRMSD 478
SFL+ QVR++N+++ + QL ++ LRR +R+ K L+ +P +
Sbjct: 472 ASFLVAQVRKLNDSSS-RRPQLCDAGLKTWLRRMHADRD----KAGDGLEATPKVAK--- 523
Query: 479 VPEGVIRVHAPLLSKVSMAIQLNNQTKAKDILAKFQYENSHGSS---------------E 523
I+V P+ K + + L TK +L +F S GS
Sbjct: 524 -----IQVVWPI--KDPLKVPLTPSTKVAHVLRQFTEHLSPGSKGQEDSEDMDSLLLHHR 576
Query: 524 CIKIQNQRLYEIGGNIGEHCLDPDAYILDVYRINPQAEWVIK 565
++ N LYE+GGNI EH LDPDAY+LD+YR NP EWV+K
Sbjct: 577 SMESANILLYEVGGNINEHRLDPDAYLLDLYRANPHGEWVLK 618
>gi|239746488 PREDICTED: Rho GTPase-activating protein 18-like [Homo
sapiens]
Length = 622
Score = 302 bits (773), Expect = 6e-82
Identities = 181/462 (39%), Positives = 265/462 (57%), Gaps = 37/462 (8%)
Query: 125 EELSFEVSYSEMVTEALKRNKLKKSEIKKEDYV-LTKFNVQKTRFGLTEAGDLSAEDMKK 183
E + + +YSE L+R++ + L KF V K R G+T GDLS +DM+K
Sbjct: 173 EAFNMDSAYSEQAAVLLQRSRPSRGGTSAWGKCSLPKFTVPKGRLGVTRIGDLSLQDMRK 232
Query: 184 IRHLSLIELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVPLVL 243
+ L+LIELTA D G+ LKR+K K K + +FGVPL LL+ D K P +VPLVL
Sbjct: 233 VPSLALIELTALCDILGLDLKRSKAGKWKAAETRLFGVPLDSLLEADHKVLPSTQVPLVL 292
Query: 244 QKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAAVMLKAF 303
Q +E+ GL+ EGI R+ G A+VK ++L+ F A F WD++ H +A+ +LK F
Sbjct: 293 QALLSCLEKRGLDMEGILRVPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDASDLLKRF 352
Query: 304 FRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFNKVI 363
R+LPT L EY+PAF +++ P++K + Q LHL+++ LP+ NR+A +AL+ F KV+
Sbjct: 353 IRKLPTPLLTAEYLPAF-AVVPNIPNLKQRLQVLHLLILILPEPNRNALKALLEFLRKVV 411
Query: 364 ANESKNRMSLWNISTVMAPNLFFSRS---KHSDYEELLLANTAAHIIRLMLKYQKILWKV 420
A E N+M+L N+STVMAPNLF + K +E LA AA ++++M+ YQ +LW V
Sbjct: 412 AREQHNKMTLRNVSTVMAPNLFLHQGRPPKLPKGKEKQLAEGAAEVVQIMVHYQDLLWTV 471
Query: 421 PSFLITQVRRMNEATMLLKKQL--PSVRKLLRRKTLERETASPKTSKVLQKSPSARRMSD 478
SFL+ QVR++N+++ + QL ++ LRR +R+ K L+ +P +
Sbjct: 472 ASFLVAQVRKLNDSSS-RRPQLCDAGLKTWLRRMHADRD----KAGDGLEATPKVAK--- 523
Query: 479 VPEGVIRVHAPLLSKVSMAIQLNNQTKAKDILAKFQYENSHGSS---------------E 523
I+V P+ K + + L TK +L +F S GS
Sbjct: 524 -----IQVVWPI--KDPLKVPLTPSTKVAHVLRQFTEHLSPGSKGQEDSEDMDSLLLHHR 576
Query: 524 CIKIQNQRLYEIGGNIGEHCLDPDAYILDVYRINPQAEWVIK 565
++ N LYE+GGNI EH LDPDAY+LD+YR NP EWV+K
Sbjct: 577 SMESANILLYEVGGNINEHRLDPDAYLLDLYRANPHGEWVLK 618
>gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens]
Length = 1271
Score = 90.5 bits (223), Expect = 4e-18
Identities = 74/270 (27%), Positives = 122/270 (45%), Gaps = 12/270 (4%)
Query: 125 EELSFEVSYSEMVTEALKRNKLKKSEIKKEDYVLTKFNVQKTRFGLTEAGDLSAEDMKKI 184
EE E+ S+ + K++I KED T + K + L + + +
Sbjct: 960 EEFEIELEGSQTLRILCYEKCYNKTKIPKEDGESTDRLMGKGQVQLDPQALQDRDWQRTV 1019
Query: 185 RHLSLIE--LTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVPLV 242
++ IE L+ F++ LKR + K G+FGV + V+ +R K VP +
Sbjct: 1020 IAMNGIEVKLSVKFNSREFSLKRMPSRK----QTGVFGVKIAVVTKRERSK-----VPYI 1070
Query: 243 LQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAAVMLKA 302
+++ E++E G+E GI+R+SG ++ + D +M A LK
Sbjct: 1071 VRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDVNNKDVSVMMSEMDVNAIAGTLKL 1130
Query: 303 FFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFNKV 362
+FRELP LF E+ P F + V + L+L+ ++LP+AN L+ +V
Sbjct: 1131 YFRELPEPLFTDEFYPNFAEGIALSDPVAKESCMLNLL-LSLPEANLLTFLFLLDHLKRV 1189
Query: 363 IANESKNRMSLWNISTVMAPNLFFSRSKHS 392
E+ N+MSL N++TV P L K S
Sbjct: 1190 AEKEAVNKMSLHNLATVFGPTLLRPSEKES 1219
>gi|56119110 family with sequence similarity 13, member A1 isoform a
[Homo sapiens]
Length = 1023
Score = 89.7 bits (221), Expect = 6e-18
Identities = 92/324 (28%), Positives = 144/324 (44%), Gaps = 41/324 (12%)
Query: 179 EDMKKIRHLSLIELTAFF--DAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPG 236
EDMKKI + L E F FG+ L+ + E+ +NGI
Sbjct: 19 EDMKKIVAVPLNEQKDFTYQKLFGVSLQ--ELERQGLTENGI------------------ 58
Query: 237 VKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREA 296
P V+ E + + GL EG+FR++G V+Q R + ++ + K +C A
Sbjct: 59 ---PAVVWNIVEYLTQHGLTQEGLFRVNGNVKVVEQLRLKFESGVPVELGKDGDVC--SA 113
Query: 297 AVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALM 356
A +LK F RELP SL P FI L + G + VQ +L ++ LPD + + L
Sbjct: 114 ASLLKLFLRELPDSLITSALQPRFIQLFQDGRN-DVQESSLRDLIKELPDTHYCLLKYLC 172
Query: 357 TFFNKVIANESKNRMSLWNISTVMAPNLFFSRSKHSDYEELLLANTAAHIIRLMLKYQKI 416
F KV + +NRM++ N++TV PN F +E L N I+ +L+
Sbjct: 173 QFLTKVAKHHVQNRMNVHNLATVFGPNCFHVPPGLEGMKEQDLCN---KIMAKILENYNT 229
Query: 417 LWKVPSFLITQVRRMNEATMLLKKQL--PSVRKLLRRKTLERETASPKTSKVLQKSPSAR 474
L++V +R N A +++ K++ + +L + LER+ P + KS S
Sbjct: 230 LFEVEYTENDHLRCENLARLIIVKEVYYKNSLPILLTRGLERDMPKPPPKTKIPKSRS-- 287
Query: 475 RMSDVPEGVIRVHAPLLSKVSMAI 498
EG I+ H L ++S I
Sbjct: 288 ------EGSIQAHRVLQPELSDGI 305
>gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens]
Length = 1227
Score = 88.2 bits (217), Expect = 2e-17
Identities = 60/203 (29%), Positives = 98/203 (48%), Gaps = 10/203 (4%)
Query: 190 IELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVPLVLQKFFEK 249
++L+ F++ LKR + K G+FGV + V+ +R K VP ++++ E+
Sbjct: 983 VKLSVKFNSREFSLKRMPSRK----QTGVFGVKIAVVTKRERSK-----VPYIVRQCVEE 1033
Query: 250 VEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAAVMLKAFFRELPT 309
+E G+E GI+R+SG ++ + D +M A LK +FRELP
Sbjct: 1034 IERRGMEEVGIYRVSGVATDIQALKAAFDVNNKDVSVMMSEMDVNAIAGTLKLYFRELPE 1093
Query: 310 SLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFNKVIANESKN 369
LF E+ P F + V + L+L+ ++LP+AN L+ +V E+ N
Sbjct: 1094 PLFTDEFYPNFAEGIALSDPVAKESCMLNLL-LSLPEANLLTFLFLLDHLKRVAEKEAVN 1152
Query: 370 RMSLWNISTVMAPNLFFSRSKHS 392
+MSL N++TV P L K S
Sbjct: 1153 KMSLHNLATVFGPTLLRPSEKES 1175
>gi|188497642 ARHGAP15 [Homo sapiens]
Length = 475
Score = 84.0 bits (206), Expect = 3e-16
Identities = 54/181 (29%), Positives = 94/181 (51%), Gaps = 8/181 (4%)
Query: 239 VPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYR--EELDAKFNADKFKWDKMCHREA 296
VP +++ E VE+ GL+ +GI+R+SG A +++ R + K N D +W+ +
Sbjct: 294 VPWFVKQCIEAVEKRGLDVDGIYRVSGNLATIQKLRFIVNQEEKLNLDDSQWEDIHVVTG 353
Query: 297 AVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALM 356
A LK FFRELP LFP + F+ +++ + + +A+ +V LP NRD + L
Sbjct: 354 A--LKMFFRELPEPLFPYSFFEQFVEAIKKQDN-NTRIEAVKSLVQKLPPPNRDTMKVLF 410
Query: 357 TFFNKVIANESKNRMSLWNISTVMAPNLFFSRSKHSDYE-ELLLANTAAHIIRLMLKYQK 415
K++A SKN MS ++ V P L + ++ + ++ N A + ++ +Y K
Sbjct: 411 GHLTKIVAKASKNLMSTQSLGIVFGPTLLRAENETGNMAIHMVYQNQIAEL--MLSEYSK 468
Query: 416 I 416
I
Sbjct: 469 I 469
>gi|229094128 active breakpoint cluster region-related protein
isoform c [Homo sapiens]
Length = 813
Score = 83.6 bits (205), Expect = 5e-16
Identities = 58/195 (29%), Positives = 93/195 (47%), Gaps = 10/195 (5%)
Query: 190 IELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVPLVLQKFFEK 249
+E + F + + LKR ++K G+FGV ++V+ +R K VP ++++ E+
Sbjct: 574 VEFSMKFTSRDMSLKRTPSKK----QTGVFGVKISVVTKRERSK-----VPYIVRQCVEE 624
Query: 250 VEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAAVMLKAFFRELPT 309
VE+ G+E GI+R+SG ++ + DA M A LK +FRELP
Sbjct: 625 VEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDMDINAIAGTLKLYFRELPE 684
Query: 310 SLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFNKVIANESKN 369
L PAF+ + + +HL+ +LPD N L+ +V E N
Sbjct: 685 PLLTDRLYPAFMEGIALSDPAAKENCMMHLL-RSLPDPNLITFLFLLEHLKRVAEKEPIN 743
Query: 370 RMSLWNISTVMAPNL 384
+MSL N++TV P L
Sbjct: 744 KMSLHNLATVFGPTL 758
>gi|33188433 deleted in liver cancer 1 isoform 1 [Homo sapiens]
Length = 1528
Score = 83.6 bits (205), Expect = 5e-16
Identities = 61/219 (27%), Positives = 106/219 (48%), Gaps = 18/219 (8%)
Query: 177 SAEDMKKIRHLSLIELTAFFDAFGIQLKRN---------KTEKVKG-RDNGIFGVPLTVL 226
S M ++ SL++LTA + + K K KV +D +FGVPLTV
Sbjct: 1024 SVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVN 1083
Query: 227 LDGDRKKDPGVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKF 286
+ + G +P +Q+ + L+ G+FR SG ++++ R+ + D
Sbjct: 1084 V-----QRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAI--DCV 1136
Query: 287 KWDKMCHREAAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPD 346
++ + A MLK +FR+LP L + F+ + + P + + QA+ +M LPD
Sbjct: 1137 NYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQ-RLQAIKAAIMLLPD 1195
Query: 347 ANRDAAQALMTFFNKVIANESKNRMSLWNISTVMAPNLF 385
NR+ Q L+ F + V A +N+M+ N++ +AP+LF
Sbjct: 1196 ENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLF 1234
Score = 41.2 bits (95), Expect = 0.003
Identities = 40/156 (25%), Positives = 65/156 (41%), Gaps = 20/156 (12%)
Query: 52 SMPDDASLNSTTLSDASQDKEGSFAVPRSDSVAILETIPVLPVHSNGSPEPGQPVQNAI- 110
S P D TL D S+ +E S SV L + LP H+ S + P N++
Sbjct: 570 SHPKDGPSPGGTLMDLSERQEVS-------SVRSLSSTGSLPSHAPPSEDAATPRTNSVI 622
Query: 111 ----------SDDDFLEKNIPPEAEELSFEVSYSEMVTEALKRNKLKKSEIKKEDYVLTK 160
+DD F P E SF + E ++ R+ LK+ E K
Sbjct: 623 SVCSSSNLAGNDDSFGSLPSPKELSSFSFSMKGHEKTAKSKTRSLLKRMESLKLKSSHHS 682
Query: 161 FNVQKTRFGLTEAGDLSAE--DMKKIRHLSLIELTA 194
+ ++ GL +G + E D +K++ L+ +E++A
Sbjct: 683 KHKAPSKLGLIISGPILQEGMDEEKLKQLNCVEISA 718
>gi|33188437 deleted in liver cancer 1 isoform 2 [Homo sapiens]
Length = 1091
Score = 83.6 bits (205), Expect = 5e-16
Identities = 61/219 (27%), Positives = 106/219 (48%), Gaps = 18/219 (8%)
Query: 177 SAEDMKKIRHLSLIELTAFFDAFGIQLKRN---------KTEKVKG-RDNGIFGVPLTVL 226
S M ++ SL++LTA + + K K KV +D +FGVPLTV
Sbjct: 587 SVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVN 646
Query: 227 LDGDRKKDPGVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKF 286
+ + G +P +Q+ + L+ G+FR SG ++++ R+ + D
Sbjct: 647 V-----QRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAI--DCV 699
Query: 287 KWDKMCHREAAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPD 346
++ + A MLK +FR+LP L + F+ + + P + + QA+ +M LPD
Sbjct: 700 NYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQ-RLQAIKAAIMLLPD 758
Query: 347 ANRDAAQALMTFFNKVIANESKNRMSLWNISTVMAPNLF 385
NR+ Q L+ F + V A +N+M+ N++ +AP+LF
Sbjct: 759 ENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLF 797
Score = 41.2 bits (95), Expect = 0.003
Identities = 40/156 (25%), Positives = 65/156 (41%), Gaps = 20/156 (12%)
Query: 52 SMPDDASLNSTTLSDASQDKEGSFAVPRSDSVAILETIPVLPVHSNGSPEPGQPVQNAI- 110
S P D TL D S+ +E S SV L + LP H+ S + P N++
Sbjct: 133 SHPKDGPSPGGTLMDLSERQEVS-------SVRSLSSTGSLPSHAPPSEDAATPRTNSVI 185
Query: 111 ----------SDDDFLEKNIPPEAEELSFEVSYSEMVTEALKRNKLKKSEIKKEDYVLTK 160
+DD F P E SF + E ++ R+ LK+ E K
Sbjct: 186 SVCSSSNLAGNDDSFGSLPSPKELSSFSFSMKGHEKTAKSKTRSLLKRMESLKLKSSHHS 245
Query: 161 FNVQKTRFGLTEAGDLSAE--DMKKIRHLSLIELTA 194
+ ++ GL +G + E D +K++ L+ +E++A
Sbjct: 246 KHKAPSKLGLIISGPILQEGMDEEKLKQLNCVEISA 281
>gi|38679957 active breakpoint cluster region-related protein
isoform a [Homo sapiens]
Length = 859
Score = 83.6 bits (205), Expect = 5e-16
Identities = 58/195 (29%), Positives = 93/195 (47%), Gaps = 10/195 (5%)
Query: 190 IELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVPLVLQKFFEK 249
+E + F + + LKR ++K G+FGV ++V+ +R K VP ++++ E+
Sbjct: 620 VEFSMKFTSRDMSLKRTPSKK----QTGVFGVKISVVTKRERSK-----VPYIVRQCVEE 670
Query: 250 VEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAAVMLKAFFRELPT 309
VE+ G+E GI+R+SG ++ + DA M A LK +FRELP
Sbjct: 671 VEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDMDINAIAGTLKLYFRELPE 730
Query: 310 SLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFNKVIANESKN 369
L PAF+ + + +HL+ +LPD N L+ +V E N
Sbjct: 731 PLLTDRLYPAFMEGIALSDPAAKENCMMHLL-RSLPDPNLITFLFLLEHLKRVAEKEPIN 789
Query: 370 RMSLWNISTVMAPNL 384
+MSL N++TV P L
Sbjct: 790 KMSLHNLATVFGPTL 804
>gi|38679954 active breakpoint cluster region-related protein
isoform b [Homo sapiens]
Length = 822
Score = 83.6 bits (205), Expect = 5e-16
Identities = 58/195 (29%), Positives = 93/195 (47%), Gaps = 10/195 (5%)
Query: 190 IELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVPLVLQKFFEK 249
+E + F + + LKR ++K G+FGV ++V+ +R K VP ++++ E+
Sbjct: 583 VEFSMKFTSRDMSLKRTPSKK----QTGVFGVKISVVTKRERSK-----VPYIVRQCVEE 633
Query: 250 VEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAAVMLKAFFRELPT 309
VE+ G+E GI+R+SG ++ + DA M A LK +FRELP
Sbjct: 634 VEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDMDINAIAGTLKLYFRELPE 693
Query: 310 SLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFNKVIANESKN 369
L PAF+ + + +HL+ +LPD N L+ +V E N
Sbjct: 694 PLLTDRLYPAFMEGIALSDPAAKENCMMHLL-RSLPDPNLITFLFLLEHLKRVAEKEPIN 752
Query: 370 RMSLWNISTVMAPNL 384
+MSL N++TV P L
Sbjct: 753 KMSLHNLATVFGPTL 767
>gi|26986534 Rho GTPase activating protein 12 [Homo sapiens]
Length = 846
Score = 80.1 bits (196), Expect = 5e-15
Identities = 51/148 (34%), Positives = 80/148 (54%), Gaps = 6/148 (4%)
Query: 239 VPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREEL--DAKFNADKFKWDKMCHREA 296
VP ++ E VEE GL+ +GI+R+SG A +++ R + D K + + KW+ +
Sbjct: 669 VPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKLRFAVNHDEKLDLNDSKWEDIHVITG 728
Query: 297 AVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALM 356
A LK FFRELP LF + F++ +++ P +V A+ ++ LP N+D Q L
Sbjct: 729 A--LKMFFRELPEPLFTFNHFNDFVNAIKQEPRQRVA--AVKDLIRQLPKPNQDTMQILF 784
Query: 357 TFFNKVIANESKNRMSLWNISTVMAPNL 384
+VI N KNRM+ +I+ V P L
Sbjct: 785 RHLRRVIENGEKNRMTYQSIAIVFGPTL 812
>gi|41281907 StAR-related lipid transfer (START) domain containing
13 isoform beta [Homo sapiens]
Length = 1105
Score = 79.7 bits (195), Expect = 7e-15
Identities = 56/219 (25%), Positives = 105/219 (47%), Gaps = 18/219 (8%)
Query: 177 SAEDMKKIRHLSLIELTAFFDAFGIQLKRNKTEKVKG----------RDNGIFGVPLTVL 226
+A + ++ SL+ LTA + + K T V +D +FGVPL V
Sbjct: 601 TASQLSLLQRFSLLRLTAIMEKHSMSNKHGWTWSVPKFMKRMKVPDYKDKAVFGVPLIVH 660
Query: 227 LDGDRKKDPGVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKF 286
+ + G +P +Q+ + + L+ G+FR SG +++ R+ ++ F +
Sbjct: 661 V-----QRTGQPLPQSIQQALRYLRSNCLDQVGLFRKSGVKSRIHALRQ-MNENF-PENV 713
Query: 287 KWDKMCHREAAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPD 346
++ + A M+K FFR+LP LF + F+ + + + + QA+ ++ L D
Sbjct: 714 NYEDQSAYDVADMVKQFFRDLPEPLFTNKLSETFLHIYQYVSKEQ-RLQAVQAAILLLAD 772
Query: 347 ANRDAAQALMTFFNKVIANESKNRMSLWNISTVMAPNLF 385
NR+ Q L+ F N V+ +N+M+ N++ +AP+LF
Sbjct: 773 ENREVLQTLLCFLNDVVNLVEENQMTPMNLAVCLAPSLF 811
>gi|16445031 StAR-related lipid transfer (START) domain containing
13 isoform gamma [Homo sapiens]
Length = 995
Score = 79.7 bits (195), Expect = 7e-15
Identities = 56/219 (25%), Positives = 105/219 (47%), Gaps = 18/219 (8%)
Query: 177 SAEDMKKIRHLSLIELTAFFDAFGIQLKRNKTEKVKG----------RDNGIFGVPLTVL 226
+A + ++ SL+ LTA + + K T V +D +FGVPL V
Sbjct: 491 TASQLSLLQRFSLLRLTAIMEKHSMSNKHGWTWSVPKFMKRMKVPDYKDKAVFGVPLIVH 550
Query: 227 LDGDRKKDPGVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKF 286
+ + G +P +Q+ + + L+ G+FR SG +++ R+ ++ F +
Sbjct: 551 V-----QRTGQPLPQSIQQALRYLRSNCLDQVGLFRKSGVKSRIHALRQ-MNENF-PENV 603
Query: 287 KWDKMCHREAAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPD 346
++ + A M+K FFR+LP LF + F+ + + + + QA+ ++ L D
Sbjct: 604 NYEDQSAYDVADMVKQFFRDLPEPLFTNKLSETFLHIYQYVSKEQ-RLQAVQAAILLLAD 662
Query: 347 ANRDAAQALMTFFNKVIANESKNRMSLWNISTVMAPNLF 385
NR+ Q L+ F N V+ +N+M+ N++ +AP+LF
Sbjct: 663 ENREVLQTLLCFLNDVVNLVEENQMTPMNLAVCLAPSLF 701
>gi|41281898 StAR-related lipid transfer (START) domain containing
13 isoform alpha [Homo sapiens]
Length = 1113
Score = 79.7 bits (195), Expect = 7e-15
Identities = 56/219 (25%), Positives = 105/219 (47%), Gaps = 18/219 (8%)
Query: 177 SAEDMKKIRHLSLIELTAFFDAFGIQLKRNKTEKVKG----------RDNGIFGVPLTVL 226
+A + ++ SL+ LTA + + K T V +D +FGVPL V
Sbjct: 609 TASQLSLLQRFSLLRLTAIMEKHSMSNKHGWTWSVPKFMKRMKVPDYKDKAVFGVPLIVH 668
Query: 227 LDGDRKKDPGVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKF 286
+ + G +P +Q+ + + L+ G+FR SG +++ R+ ++ F +
Sbjct: 669 V-----QRTGQPLPQSIQQALRYLRSNCLDQVGLFRKSGVKSRIHALRQ-MNENF-PENV 721
Query: 287 KWDKMCHREAAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPD 346
++ + A M+K FFR+LP LF + F+ + + + + QA+ ++ L D
Sbjct: 722 NYEDQSAYDVADMVKQFFRDLPEPLFTNKLSETFLHIYQYVSKEQ-RLQAVQAAILLLAD 780
Query: 347 ANRDAAQALMTFFNKVIANESKNRMSLWNISTVMAPNLF 385
NR+ Q L+ F N V+ +N+M+ N++ +AP+LF
Sbjct: 781 ENREVLQTLLCFLNDVVNLVEENQMTPMNLAVCLAPSLF 819
>gi|226693398 Rho GTPase activating protein 27 isoform b [Homo
sapiens]
Length = 521
Score = 79.0 bits (193), Expect = 1e-14
Identities = 50/169 (29%), Positives = 89/169 (52%), Gaps = 10/169 (5%)
Query: 218 IFGVPLTVLLDGDRKKDPGVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVK--QYRE 275
+FG L L + +R + VP +Q+ VE GL+ +G++R+SG A ++ +Y+
Sbjct: 326 VFGCALAALCERERSR-----VPRFVQQCIRAVEARGLDIDGLYRISGNLATIQKLRYKV 380
Query: 276 ELDAKFNADKFKWDKMCHREAAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQ 335
+ D + + D +W+ + A LK FFRELP LFP + FI+ ++ + + +
Sbjct: 381 DHDERLDLDDGRWEDVHVITGA--LKLFFRELPEPLFPFSHFRQFIAAIKLQDQAR-RSR 437
Query: 336 ALHLMVMALPDANRDAAQALMTFFNKVIANESKNRMSLWNISTVMAPNL 384
+ +V +LP N D + L +VI + +NRMS+ +++ V P L
Sbjct: 438 CVRDLVRSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTL 486
>gi|40548322 Rho GTPase activating protein 27 isoform a [Homo
sapiens]
Length = 548
Score = 79.0 bits (193), Expect = 1e-14
Identities = 50/169 (29%), Positives = 89/169 (52%), Gaps = 10/169 (5%)
Query: 218 IFGVPLTVLLDGDRKKDPGVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVK--QYRE 275
+FG L L + +R + VP +Q+ VE GL+ +G++R+SG A ++ +Y+
Sbjct: 353 VFGCALAALCERERSR-----VPRFVQQCIRAVEARGLDIDGLYRISGNLATIQKLRYKV 407
Query: 276 ELDAKFNADKFKWDKMCHREAAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQ 335
+ D + + D +W+ + A LK FFRELP LFP + FI+ ++ + + +
Sbjct: 408 DHDERLDLDDGRWEDVHVITGA--LKLFFRELPEPLFPFSHFRQFIAAIKLQDQAR-RSR 464
Query: 336 ALHLMVMALPDANRDAAQALMTFFNKVIANESKNRMSLWNISTVMAPNL 384
+ +V +LP N D + L +VI + +NRMS+ +++ V P L
Sbjct: 465 CVRDLVRSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTL 513
>gi|7382480 Rho GTPase activating protein 6 isoform 4 [Homo sapiens]
Length = 771
Score = 76.3 bits (186), Expect = 7e-14
Identities = 69/247 (27%), Positives = 114/247 (46%), Gaps = 28/247 (11%)
Query: 238 KVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAA 297
+VP ++ + +E+ GL++ GIFR+ +V+Q REE D D ++ + A
Sbjct: 206 QVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDR--GIDVSLEEEHSVHDVA 263
Query: 298 VMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMT 357
+LK F R++P L E AFI+ + P + Q L L++ LP N D L+
Sbjct: 264 ALLKEFLRDMPDPLLTRELYTAFINTLLLEP--EEQLGTLQLLIYLLPPCNCDTLHRLLQ 321
Query: 358 FFNKVIA----NESK-------NRMSLWNISTVMAPNLFFSRSKHSDYEELLLANTAAH- 405
F + V N SK N+M+ N++T+ PNL + K SD E + ++ A
Sbjct: 322 FLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNL-LHKQKSSDKEFSVQSSARAEE 380
Query: 406 ------IIRLMLKYQKILWKVPSFLITQVRRMNEATMLLKKQLPSVRKLLRRKTLERETA 459
+++ M++ + L+ VP L +V LL+ V LLRRK + +
Sbjct: 381 STAIIAVVQKMIENYEALFMVPPDLQNEV-----LISLLETDPDVVDYLLRRKASQSSSP 435
Query: 460 SPKTSKV 466
S+V
Sbjct: 436 DMLQSEV 442
>gi|95091988 Rho GTPase activating protein 6 isoform 3 [Homo
sapiens]
Length = 765
Score = 76.3 bits (186), Expect = 7e-14
Identities = 69/247 (27%), Positives = 114/247 (46%), Gaps = 28/247 (11%)
Query: 238 KVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAA 297
+VP ++ + +E+ GL++ GIFR+ +V+Q REE D D ++ + A
Sbjct: 409 QVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDR--GIDVSLEEEHSVHDVA 466
Query: 298 VMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMT 357
+LK F R++P L E AFI+ + P + Q L L++ LP N D L+
Sbjct: 467 ALLKEFLRDMPDPLLTRELYTAFINTLLLEP--EEQLGTLQLLIYLLPPCNCDTLHRLLQ 524
Query: 358 FFNKVIA----NESK-------NRMSLWNISTVMAPNLFFSRSKHSDYEELLLANTAAH- 405
F + V N SK N+M+ N++T+ PNL + K SD E + ++ A
Sbjct: 525 FLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNL-LHKQKSSDKEFSVQSSARAEE 583
Query: 406 ------IIRLMLKYQKILWKVPSFLITQVRRMNEATMLLKKQLPSVRKLLRRKTLERETA 459
+++ M++ + L+ VP L +V LL+ V LLRRK + +
Sbjct: 584 STAIIAVVQKMIENYEALFMVPPDLQNEV-----LISLLETDPDVVDYLLRRKASQSSSP 638
Query: 460 SPKTSKV 466
S+V
Sbjct: 639 DMLQSEV 645
>gi|95091875 Rho GTPase activating protein 6 isoform 1 [Homo
sapiens]
Length = 974
Score = 76.3 bits (186), Expect = 7e-14
Identities = 69/247 (27%), Positives = 114/247 (46%), Gaps = 28/247 (11%)
Query: 238 KVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAA 297
+VP ++ + +E+ GL++ GIFR+ +V+Q REE D D ++ + A
Sbjct: 409 QVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDR--GIDVSLEEEHSVHDVA 466
Query: 298 VMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMT 357
+LK F R++P L E AFI+ + P + Q L L++ LP N D L+
Sbjct: 467 ALLKEFLRDMPDPLLTRELYTAFINTLLLEP--EEQLGTLQLLIYLLPPCNCDTLHRLLQ 524
Query: 358 FFNKVIA----NESK-------NRMSLWNISTVMAPNLFFSRSKHSDYEELLLANTAAH- 405
F + V N SK N+M+ N++T+ PNL + K SD E + ++ A
Sbjct: 525 FLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNL-LHKQKSSDKEFSVQSSARAEE 583
Query: 406 ------IIRLMLKYQKILWKVPSFLITQVRRMNEATMLLKKQLPSVRKLLRRKTLERETA 459
+++ M++ + L+ VP L +V LL+ V LLRRK + +
Sbjct: 584 STAIIAVVQKMIENYEALFMVPPDLQNEV-----LISLLETDPDVVDYLLRRKASQSSSP 638
Query: 460 SPKTSKV 466
S+V
Sbjct: 639 DMLQSEV 645
>gi|5803145 ralA binding protein 1 [Homo sapiens]
Length = 655
Score = 75.9 bits (185), Expect = 9e-14
Identities = 48/170 (28%), Positives = 89/170 (52%), Gaps = 5/170 (2%)
Query: 218 IFGVPLTVLLDGDRKKDPGVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREEL 277
IFG+PL ++ D G+++P V ++ + VE+ G++ EGI+R+SG +KV + +
Sbjct: 189 IFGIPLADAVERTMMYD-GIRLPAVFRECIDYVEKYGMKCEGIYRVSGIKSKVDELKAAY 247
Query: 278 DAKFNADKFKWDKMCHREAAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQAL 337
D + + + ++ A +LK + R+LP +L E +P F R + + Q
Sbjct: 248 DREESTNLEDYEP---NTVASLLKQYLRDLPENLLTKELMPRFEEACGRTTETE-KVQEF 303
Query: 338 HLMVMALPDANRDAAQALMTFFNKVIANESKNRMSLWNISTVMAPNLFFS 387
++ LP+ N L+ + VIA E + +M++ NIS V++P + S
Sbjct: 304 QRLLKELPECNYLLISWLIVHMDHVIAKELETKMNIQNISIVLSPTVQIS 353
>gi|215820652 StAR-related lipid transfer (START) domain containing
8 isoform b [Homo sapiens]
Length = 1023
Score = 75.9 bits (185), Expect = 9e-14
Identities = 54/210 (25%), Positives = 103/210 (49%), Gaps = 23/210 (10%)
Query: 188 SLIELTAFFDAFGIQ------------LKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDP 235
SL+ LTAF + + + ++RNKT +G+ +FGVP + + +
Sbjct: 529 SLLRLTAFMEKYTVPHKQGWVWSMPKFMRRNKTPDYRGQH--VFGVPPLIHV-----QRT 581
Query: 236 GVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHRE 295
G +P +Q+ + L+ GIFR SG ++++ R+ + + D ++ +
Sbjct: 582 GQPLPQSIQQAMRYLRSQCLDQVGIFRKSGVKSRIQNLRQMNET--SPDNVCYEGQSAYD 639
Query: 296 AAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQAL 355
A +LK +FR+LP +F + F+ + + P + A + LPD NR+ Q L
Sbjct: 640 VADLLKQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQ-WLAAAQAATLLLPDENREVLQTL 698
Query: 356 MTFFNKVIANESKNRMSLWNISTVMAPNLF 385
+ F + IA+ +N+M+ N++ +AP++F
Sbjct: 699 LYFLSD-IASAEENQMTAGNLAVCLAPSIF 727
>gi|215820650 StAR-related lipid transfer (START) domain containing
8 isoform a [Homo sapiens]
Length = 1103
Score = 75.9 bits (185), Expect = 9e-14
Identities = 54/210 (25%), Positives = 103/210 (49%), Gaps = 23/210 (10%)
Query: 188 SLIELTAFFDAFGIQ------------LKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDP 235
SL+ LTAF + + + ++RNKT +G+ +FGVP + + +
Sbjct: 609 SLLRLTAFMEKYTVPHKQGWVWSMPKFMRRNKTPDYRGQH--VFGVPPLIHV-----QRT 661
Query: 236 GVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHRE 295
G +P +Q+ + L+ GIFR SG ++++ R+ + + D ++ +
Sbjct: 662 GQPLPQSIQQAMRYLRSQCLDQVGIFRKSGVKSRIQNLRQMNET--SPDNVCYEGQSAYD 719
Query: 296 AAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQAL 355
A +LK +FR+LP +F + F+ + + P + A + LPD NR+ Q L
Sbjct: 720 VADLLKQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQ-WLAAAQAATLLLPDENREVLQTL 778
Query: 356 MTFFNKVIANESKNRMSLWNISTVMAPNLF 385
+ F + IA+ +N+M+ N++ +AP++F
Sbjct: 779 LYFLSD-IASAEENQMTAGNLAVCLAPSIF 807
>gi|31543659 StAR-related lipid transfer (START) domain containing 8
isoform b [Homo sapiens]
Length = 1023
Score = 75.9 bits (185), Expect = 9e-14
Identities = 54/210 (25%), Positives = 103/210 (49%), Gaps = 23/210 (10%)
Query: 188 SLIELTAFFDAFGIQ------------LKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDP 235
SL+ LTAF + + + ++RNKT +G+ +FGVP + + +
Sbjct: 529 SLLRLTAFMEKYTVPHKQGWVWSMPKFMRRNKTPDYRGQH--VFGVPPLIHV-----QRT 581
Query: 236 GVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHRE 295
G +P +Q+ + L+ GIFR SG ++++ R+ + + D ++ +
Sbjct: 582 GQPLPQSIQQAMRYLRSQCLDQVGIFRKSGVKSRIQNLRQMNET--SPDNVCYEGQSAYD 639
Query: 296 AAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQAL 355
A +LK +FR+LP +F + F+ + + P + A + LPD NR+ Q L
Sbjct: 640 VADLLKQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQ-WLAAAQAATLLLPDENREVLQTL 698
Query: 356 MTFFNKVIANESKNRMSLWNISTVMAPNLF 385
+ F + IA+ +N+M+ N++ +AP++F
Sbjct: 699 LYFLSD-IASAEENQMTAGNLAVCLAPSIF 727
>gi|150417981 glucocorticoid receptor DNA binding factor 1 [Homo
sapiens]
Length = 1499
Score = 73.2 bits (178), Expect = 6e-13
Identities = 58/201 (28%), Positives = 95/201 (47%), Gaps = 16/201 (7%)
Query: 215 DNGIFGVPLTVLLDGDRKKDPGVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYR 274
++ FGVPLT ++ P +P+ +++ E +E +GL +EGI+R+SG ++++ +
Sbjct: 1243 ESNYFGVPLTTVVT------PEKPIPIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQ 1296
Query: 275 EELDAKFNADKFKWDKMCHREAAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQF 334
+ D N D + D + A M K+FF ELP L P I L+E + +
Sbjct: 1297 RQFDQDHNLDLAEKDFTVNTVAGAM-KSFFSELPDPLVPYN---MQIDLVE-AHKINDRE 1351
Query: 335 QALHLMVMAL---PDANRDAAQALMTFFNKVIANESKNRMSLWNISTVMAPNLFFSRSKH 391
Q LH + L P N + + +++ NKV N N M+ N+S P L R
Sbjct: 1352 QKLHALKEVLKKFPKENHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTLM--RPDF 1409
Query: 392 SDYEELLLANTAAHIIRLMLK 412
S + L T II L ++
Sbjct: 1410 STMDALTATRTYQTIIELFIQ 1430
>gi|156119615 myosin IXA [Homo sapiens]
Length = 2548
Score = 71.6 bits (174), Expect = 2e-12
Identities = 72/291 (24%), Positives = 125/291 (42%), Gaps = 27/291 (9%)
Query: 219 FGVPLTVLLDGDRKKDPGVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELD 278
FGV L+ L DR VPLV++K +E GL +EGI+R SG T K+K+ R+ LD
Sbjct: 2061 FGVELSRLTSEDRT------VPLVVEKLINYIEMHGLYTEGIYRKSGSTNKIKELRQGLD 2114
Query: 279 AKFNADKFKWDKMCHREAAVMLKAFFRELPTSLFPVEYIPAFI---SLMERGPHVKVQFQ 335
+A+ D A + K + R+LP L E F+ L ER K +
Sbjct: 2115 T--DAESVNLDDYNIHVIASVFKQWLRDLPNPLMTFELYEEFLRAMGLQER----KETIR 2168
Query: 336 ALHLMVMALPDANRDAAQALMTFFNKVIANESKNRMSLWNISTVMAPNLFFSRSKHSDYE 395
++ ++ L + + + L+ ++ E NRMS ++ V AP + +
Sbjct: 2169 GVYSVIDQLSRTHLNTLERLIFHLVRIALQEDTNRMSANALAIVFAPCILRCPDTTDPLQ 2228
Query: 396 ELLLANTAAHIIRLMLKYQKILWKVPSFLITQVRRMNEATMLLKKQLPSVRKLLRRKTLE 455
+ + + L++ Q +K + + + A K +L +R+ + + +
Sbjct: 2229 SVQDISKTTTCVELIVVEQMNKYKA---RLKDISSLEFAENKAKTRLSLIRRSMGKGRIR 2285
Query: 456 RETASPKTSKVLQKSPSARRMSDVPEGVIRVHAPLLSKVSMAIQLNNQTKA 506
R +S V+ + PS +SDV E L S+ +M + Q +A
Sbjct: 2286 RGNYPGPSSPVVVRLPS---VSDVSE------ETLTSEAAMETDITEQQQA 2327
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.132 0.374
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,334,475
Number of Sequences: 37866
Number of extensions: 879140
Number of successful extensions: 3190
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 85
Number of HSP's successfully gapped in prelim test: 43
Number of HSP's that attempted gapping in prelim test: 2921
Number of HSP's gapped (non-prelim): 168
length of query: 570
length of database: 18,247,518
effective HSP length: 108
effective length of query: 462
effective length of database: 14,157,990
effective search space: 6540991380
effective search space used: 6540991380
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.