Guide to the Human Genome
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Search of human proteins with 59710111

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|59710111 Rho GTPase activating protein 28 isoform b [Homo
sapiens]
         (563 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|59710111 Rho GTPase activating protein 28 isoform b [Homo sap...  1106   0.0  
gi|59710113 Rho GTPase activating protein 28 isoform a [Homo sap...  1013   0.0  
gi|39932589 Rho GTPase activating protein 18 [Homo sapiens]           332   7e-91
gi|239757488 PREDICTED: chromosome 20 open reading frame 95 [Hom...   253   3e-67
gi|239752003 PREDICTED: chromosome 20 open reading frame 95 [Hom...   253   3e-67
gi|239746488 PREDICTED: Rho GTPase-activating protein 18-like [H...   253   3e-67
gi|56119110 family with sequence similarity 13, member A1 isofor...    91   3e-18
gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens]         91   4e-18
gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens]         88   2e-17
gi|188497642 ARHGAP15 [Homo sapiens]                                   84   3e-16
gi|229094128 active breakpoint cluster region-related  protein i...    84   4e-16
gi|33188433 deleted in liver cancer 1 isoform 1 [Homo sapiens]         84   4e-16
gi|33188437 deleted in liver cancer 1 isoform 2 [Homo sapiens]         84   4e-16
gi|38679957 active breakpoint cluster region-related  protein is...    84   4e-16
gi|38679954 active breakpoint cluster region-related  protein is...    84   4e-16
gi|26986534 Rho GTPase activating protein 12 [Homo sapiens]            80   5e-15
gi|41281907 StAR-related lipid transfer (START) domain containin...    80   6e-15
gi|16445031 StAR-related lipid transfer (START) domain containin...    80   6e-15
gi|41281898 StAR-related lipid transfer (START) domain containin...    80   6e-15
gi|226693398 Rho GTPase activating protein 27 isoform b [Homo sa...    79   1e-14
gi|40548322 Rho GTPase activating protein 27 isoform a [Homo sap...    79   1e-14
gi|7382480 Rho GTPase activating protein 6 isoform 4 [Homo sapiens]    76   7e-14
gi|95091988 Rho GTPase activating protein 6 isoform 3 [Homo sapi...    76   7e-14
gi|95091875 Rho GTPase activating protein 6 isoform 1 [Homo sapi...    76   7e-14
gi|5803145 ralA binding protein 1 [Homo sapiens]                       76   9e-14
gi|215820652 StAR-related lipid transfer (START) domain containi...    76   9e-14
gi|215820650 StAR-related lipid transfer (START) domain containi...    76   9e-14
gi|31543659 StAR-related lipid transfer (START) domain containin...    76   9e-14
gi|156119615 myosin IXA [Homo sapiens]                                 75   2e-13
gi|150417981 glucocorticoid receptor DNA binding factor 1 [Homo ...    73   6e-13

>gi|59710111 Rho GTPase activating protein 28 isoform b [Homo
           sapiens]
          Length = 563

 Score = 1106 bits (2860), Expect = 0.0
 Identities = 563/563 (100%), Positives = 563/563 (100%)

Query: 1   MRKKDKQSIRDVRDIFGVSESPPRDTCGNHTNQLDGTKEERELPRVIKTSGSMPDDASLN 60
           MRKKDKQSIRDVRDIFGVSESPPRDTCGNHTNQLDGTKEERELPRVIKTSGSMPDDASLN
Sbjct: 1   MRKKDKQSIRDVRDIFGVSESPPRDTCGNHTNQLDGTKEERELPRVIKTSGSMPDDASLN 60

Query: 61  STTLSDASQDKEGSFAVPRSDSVAILETIPVLPVHSNGSPEPGQPVQNAISDDDFLEKNI 120
           STTLSDASQDKEGSFAVPRSDSVAILETIPVLPVHSNGSPEPGQPVQNAISDDDFLEKNI
Sbjct: 61  STTLSDASQDKEGSFAVPRSDSVAILETIPVLPVHSNGSPEPGQPVQNAISDDDFLEKNI 120

Query: 121 PPEAEELSFEVSYSEMVTEALKRNKLKKSEIKKEDYVLTKFNVQKTRFGLTEAGDLSAED 180
           PPEAEELSFEVSYSEMVTEALKRNKLKKSEIKKEDYVLTKFNVQKTRFGLTEAGDLSAED
Sbjct: 121 PPEAEELSFEVSYSEMVTEALKRNKLKKSEIKKEDYVLTKFNVQKTRFGLTEAGDLSAED 180

Query: 181 MKKIRHLSLIELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVP 240
           MKKIRHLSLIELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVP
Sbjct: 181 MKKIRHLSLIELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVP 240

Query: 241 LVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAAVML 300
           LVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAAVML
Sbjct: 241 LVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAAVML 300

Query: 301 KAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFN 360
           KAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFN
Sbjct: 301 KAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFN 360

Query: 361 KVIANESKNRMSLWNISTVMAPNLFFSRSKHSDYEELLLANTAAHIIRLMLKYQKILWKV 420
           KVIANESKNRMSLWNISTVMAPNLFFSRSKHSDYEELLLANTAAHIIRLMLKYQKILWKV
Sbjct: 361 KVIANESKNRMSLWNISTVMAPNLFFSRSKHSDYEELLLANTAAHIIRLMLKYQKILWKV 420

Query: 421 PSFLITQVRRMNEATMLLKKQLPSVRKLLRRKTLERETASPKTSKVLQKSPSARRMSDVP 480
           PSFLITQVRRMNEATMLLKKQLPSVRKLLRRKTLERETASPKTSKVLQKSPSARRMSDVP
Sbjct: 421 PSFLITQVRRMNEATMLLKKQLPSVRKLLRRKTLERETASPKTSKVLQKSPSARRMSDVP 480

Query: 481 EGVIRVHAPLLSKVSMAIQLNNQTKAKDILAKFQYENRILHWQRAALSFLNGKWVKKERE 540
           EGVIRVHAPLLSKVSMAIQLNNQTKAKDILAKFQYENRILHWQRAALSFLNGKWVKKERE
Sbjct: 481 EGVIRVHAPLLSKVSMAIQLNNQTKAKDILAKFQYENRILHWQRAALSFLNGKWVKKERE 540

Query: 541 ESTETNRSPKHVFLFTIGLDIST 563
           ESTETNRSPKHVFLFTIGLDIST
Sbjct: 541 ESTETNRSPKHVFLFTIGLDIST 563


>gi|59710113 Rho GTPase activating protein 28 isoform a [Homo
           sapiens]
          Length = 570

 Score = 1013 bits (2618), Expect = 0.0
 Identities = 517/517 (100%), Positives = 517/517 (100%)

Query: 1   MRKKDKQSIRDVRDIFGVSESPPRDTCGNHTNQLDGTKEERELPRVIKTSGSMPDDASLN 60
           MRKKDKQSIRDVRDIFGVSESPPRDTCGNHTNQLDGTKEERELPRVIKTSGSMPDDASLN
Sbjct: 1   MRKKDKQSIRDVRDIFGVSESPPRDTCGNHTNQLDGTKEERELPRVIKTSGSMPDDASLN 60

Query: 61  STTLSDASQDKEGSFAVPRSDSVAILETIPVLPVHSNGSPEPGQPVQNAISDDDFLEKNI 120
           STTLSDASQDKEGSFAVPRSDSVAILETIPVLPVHSNGSPEPGQPVQNAISDDDFLEKNI
Sbjct: 61  STTLSDASQDKEGSFAVPRSDSVAILETIPVLPVHSNGSPEPGQPVQNAISDDDFLEKNI 120

Query: 121 PPEAEELSFEVSYSEMVTEALKRNKLKKSEIKKEDYVLTKFNVQKTRFGLTEAGDLSAED 180
           PPEAEELSFEVSYSEMVTEALKRNKLKKSEIKKEDYVLTKFNVQKTRFGLTEAGDLSAED
Sbjct: 121 PPEAEELSFEVSYSEMVTEALKRNKLKKSEIKKEDYVLTKFNVQKTRFGLTEAGDLSAED 180

Query: 181 MKKIRHLSLIELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVP 240
           MKKIRHLSLIELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVP
Sbjct: 181 MKKIRHLSLIELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVP 240

Query: 241 LVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAAVML 300
           LVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAAVML
Sbjct: 241 LVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAAVML 300

Query: 301 KAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFN 360
           KAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFN
Sbjct: 301 KAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFN 360

Query: 361 KVIANESKNRMSLWNISTVMAPNLFFSRSKHSDYEELLLANTAAHIIRLMLKYQKILWKV 420
           KVIANESKNRMSLWNISTVMAPNLFFSRSKHSDYEELLLANTAAHIIRLMLKYQKILWKV
Sbjct: 361 KVIANESKNRMSLWNISTVMAPNLFFSRSKHSDYEELLLANTAAHIIRLMLKYQKILWKV 420

Query: 421 PSFLITQVRRMNEATMLLKKQLPSVRKLLRRKTLERETASPKTSKVLQKSPSARRMSDVP 480
           PSFLITQVRRMNEATMLLKKQLPSVRKLLRRKTLERETASPKTSKVLQKSPSARRMSDVP
Sbjct: 421 PSFLITQVRRMNEATMLLKKQLPSVRKLLRRKTLERETASPKTSKVLQKSPSARRMSDVP 480

Query: 481 EGVIRVHAPLLSKVSMAIQLNNQTKAKDILAKFQYEN 517
           EGVIRVHAPLLSKVSMAIQLNNQTKAKDILAKFQYEN
Sbjct: 481 EGVIRVHAPLLSKVSMAIQLNNQTKAKDILAKFQYEN 517


>gi|39932589 Rho GTPase activating protein 18 [Homo sapiens]
          Length = 663

 Score =  332 bits (850), Expect = 7e-91
 Identities = 176/405 (43%), Positives = 259/405 (63%), Gaps = 19/405 (4%)

Query: 117 EKNIPPEAE-----ELSFEVSYSEMVTEALKRNKLKKSEIKKEDYVLTKFNVQKTRFGLT 171
           EK IPPE       +++ EVS++E      + +K K  + K +D  L  F + K + G T
Sbjct: 215 EKLIPPEETPAPETDINLEVSFAEQALNQKESSKEKIQKSKGDDATLPSFRLPKDKTGTT 274

Query: 172 EAGDLSAEDMKKIRHLSLIELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDR 231
             GDL+ +DMKK+ HL+LIELTA +D  GI+LK+ K  K+K +D+G+F VPLT LL+ D+
Sbjct: 275 RIGDLAPQDMKKVCHLALIELTALYDVLGIELKQQKAVKIKTKDSGLFCVPLTALLEQDQ 334

Query: 232 KKDPGVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKM 291
           +K PG+++PL+ QK   ++EE GLE+EG+ R+ G   ++K   +EL+AKF    F W+ +
Sbjct: 335 RKVPGMRIPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESV 394

Query: 292 CHREAAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDA 351
              +AA +LK F RELP  L  VEY+ AF   ++  P  K Q QAL+L+V+ LPDANRD 
Sbjct: 395 KQHDAASLLKLFIRELPQPLLSVEYLKAF-QAVQNLPTKKQQLQALNLLVILLPDANRDT 453

Query: 352 AQALMTFFNKVIANESKNRMSLWNISTVMAPNLFFSRS---KHSDYEELLLANTAAHIIR 408
            +AL+ F  +VI N+ KN+M++ N++ VMAPNLF   +   K S+  E ++A   A+ + 
Sbjct: 454 LKALLEFLQRVIDNKEKNKMTVMNVAMVMAPNLFMCHALGLKSSEQREFVMAAGTANTMH 513

Query: 409 LMLKYQKILWKVPSFLITQVRRMNEATMLLKKQLPSVRKLLRRKTLERETASPKTSKVLQ 468
           L++KYQK+LW +P F++ QVR+ N  T   KK   +++KLL++   +RE          +
Sbjct: 514 LLIKYQKLLWTIPKFIVNQVRKQN--TENHKKDKRAMKKLLKKMAYDREK--------YE 563

Query: 469 KSPSARRMSDVPEGVIRVHAPLLSKVSMAIQLNNQTKAKDILAKF 513
           K   +   +DVP+GVIRV AP LSKVSMAIQL  + KA D+LA+F
Sbjct: 564 KQDKSTNDADVPQGVIRVQAPHLSKVSMAIQLTEELKASDVLARF 608


>gi|239757488 PREDICTED: chromosome 20 open reading frame 95 [Homo
           sapiens]
          Length = 622

 Score =  253 bits (646), Expect = 3e-67
 Identities = 144/354 (40%), Positives = 216/354 (61%), Gaps = 14/354 (3%)

Query: 125 EELSFEVSYSEMVTEALKRNKLKKSEIKKEDYV-LTKFNVQKTRFGLTEAGDLSAEDMKK 183
           E  + + +YSE     L+R++  +          L KF V K R G+T  GDLS +DM+K
Sbjct: 173 EAFNMDSAYSEQAAVLLQRSRPSRGGTSAWGKCSLPKFTVPKGRLGVTRIGDLSLQDMRK 232

Query: 184 IRHLSLIELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVPLVL 243
           +  L+LIELTA  D  G+ LKR+K  K K  +  +FGVPL  LL+ D K  P  +VPLVL
Sbjct: 233 VPSLALIELTALCDILGLDLKRSKAGKWKAAETRLFGVPLDSLLEADHKVLPSTQVPLVL 292

Query: 244 QKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAAVMLKAF 303
           Q     +E+ GL+ EGI R+ G  A+VK   ++L+  F A  F WD++ H +A+ +LK F
Sbjct: 293 QALLSCLEKRGLDMEGILRVPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDASDLLKRF 352

Query: 304 FRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFNKVI 363
            R+LPT L   EY+PAF +++   P++K + Q LHL+++ LP+ NR+A +AL+ F  KV+
Sbjct: 353 IRKLPTPLLTAEYLPAF-AVVPNIPNLKQRLQVLHLLILILPEPNRNALKALLEFLRKVV 411

Query: 364 ANESKNRMSLWNISTVMAPNLFFSRS---KHSDYEELLLANTAAHIIRLMLKYQKILWKV 420
           A E  N+M+L N+STVMAPNLF  +    K    +E  LA  AA ++++M+ YQ +LW V
Sbjct: 412 AREQHNKMTLRNVSTVMAPNLFLHQGRPPKLPKGKEKQLAEGAAEVVQIMVHYQDLLWTV 471

Query: 421 PSFLITQVRRMNEATMLLKKQL--PSVRKLLRRKTLERE------TASPKTSKV 466
            SFL+ QVR++N+++   + QL    ++  LRR   +R+       A+PK +K+
Sbjct: 472 ASFLVAQVRKLNDSSS-RRPQLCDAGLKTWLRRMHADRDKAGDGLEATPKVAKI 524


>gi|239752003 PREDICTED: chromosome 20 open reading frame 95 [Homo
           sapiens]
          Length = 622

 Score =  253 bits (646), Expect = 3e-67
 Identities = 144/354 (40%), Positives = 216/354 (61%), Gaps = 14/354 (3%)

Query: 125 EELSFEVSYSEMVTEALKRNKLKKSEIKKEDYV-LTKFNVQKTRFGLTEAGDLSAEDMKK 183
           E  + + +YSE     L+R++  +          L KF V K R G+T  GDLS +DM+K
Sbjct: 173 EAFNMDSAYSEQAAVLLQRSRPSRGGTSAWGKCSLPKFTVPKGRLGVTRIGDLSLQDMRK 232

Query: 184 IRHLSLIELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVPLVL 243
           +  L+LIELTA  D  G+ LKR+K  K K  +  +FGVPL  LL+ D K  P  +VPLVL
Sbjct: 233 VPSLALIELTALCDILGLDLKRSKAGKWKAAETRLFGVPLDSLLEADHKVLPSTQVPLVL 292

Query: 244 QKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAAVMLKAF 303
           Q     +E+ GL+ EGI R+ G  A+VK   ++L+  F A  F WD++ H +A+ +LK F
Sbjct: 293 QALLSCLEKRGLDMEGILRVPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDASDLLKRF 352

Query: 304 FRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFNKVI 363
            R+LPT L   EY+PAF +++   P++K + Q LHL+++ LP+ NR+A +AL+ F  KV+
Sbjct: 353 IRKLPTPLLTAEYLPAF-AVVPNIPNLKQRLQVLHLLILILPEPNRNALKALLEFLRKVV 411

Query: 364 ANESKNRMSLWNISTVMAPNLFFSRS---KHSDYEELLLANTAAHIIRLMLKYQKILWKV 420
           A E  N+M+L N+STVMAPNLF  +    K    +E  LA  AA ++++M+ YQ +LW V
Sbjct: 412 AREQHNKMTLRNVSTVMAPNLFLHQGRPPKLPKGKEKQLAEGAAEVVQIMVHYQDLLWTV 471

Query: 421 PSFLITQVRRMNEATMLLKKQL--PSVRKLLRRKTLERE------TASPKTSKV 466
            SFL+ QVR++N+++   + QL    ++  LRR   +R+       A+PK +K+
Sbjct: 472 ASFLVAQVRKLNDSSS-RRPQLCDAGLKTWLRRMHADRDKAGDGLEATPKVAKI 524


>gi|239746488 PREDICTED: Rho GTPase-activating protein 18-like [Homo
           sapiens]
          Length = 622

 Score =  253 bits (646), Expect = 3e-67
 Identities = 144/354 (40%), Positives = 216/354 (61%), Gaps = 14/354 (3%)

Query: 125 EELSFEVSYSEMVTEALKRNKLKKSEIKKEDYV-LTKFNVQKTRFGLTEAGDLSAEDMKK 183
           E  + + +YSE     L+R++  +          L KF V K R G+T  GDLS +DM+K
Sbjct: 173 EAFNMDSAYSEQAAVLLQRSRPSRGGTSAWGKCSLPKFTVPKGRLGVTRIGDLSLQDMRK 232

Query: 184 IRHLSLIELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVPLVL 243
           +  L+LIELTA  D  G+ LKR+K  K K  +  +FGVPL  LL+ D K  P  +VPLVL
Sbjct: 233 VPSLALIELTALCDILGLDLKRSKAGKWKAAETRLFGVPLDSLLEADHKVLPSTQVPLVL 292

Query: 244 QKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAAVMLKAF 303
           Q     +E+ GL+ EGI R+ G  A+VK   ++L+  F A  F WD++ H +A+ +LK F
Sbjct: 293 QALLSCLEKRGLDMEGILRVPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDASDLLKRF 352

Query: 304 FRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFNKVI 363
            R+LPT L   EY+PAF +++   P++K + Q LHL+++ LP+ NR+A +AL+ F  KV+
Sbjct: 353 IRKLPTPLLTAEYLPAF-AVVPNIPNLKQRLQVLHLLILILPEPNRNALKALLEFLRKVV 411

Query: 364 ANESKNRMSLWNISTVMAPNLFFSRS---KHSDYEELLLANTAAHIIRLMLKYQKILWKV 420
           A E  N+M+L N+STVMAPNLF  +    K    +E  LA  AA ++++M+ YQ +LW V
Sbjct: 412 AREQHNKMTLRNVSTVMAPNLFLHQGRPPKLPKGKEKQLAEGAAEVVQIMVHYQDLLWTV 471

Query: 421 PSFLITQVRRMNEATMLLKKQL--PSVRKLLRRKTLERE------TASPKTSKV 466
            SFL+ QVR++N+++   + QL    ++  LRR   +R+       A+PK +K+
Sbjct: 472 ASFLVAQVRKLNDSSS-RRPQLCDAGLKTWLRRMHADRDKAGDGLEATPKVAKI 524


>gi|56119110 family with sequence similarity 13, member A1 isoform a
           [Homo sapiens]
          Length = 1023

 Score = 90.9 bits (224), Expect = 3e-18
 Identities = 98/367 (26%), Positives = 157/367 (42%), Gaps = 49/367 (13%)

Query: 179 EDMKKIRHLSLIELTAFF--DAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPG 236
           EDMKKI  + L E   F     FG+ L+  + E+    +NGI                  
Sbjct: 19  EDMKKIVAVPLNEQKDFTYQKLFGVSLQ--ELERQGLTENGI------------------ 58

Query: 237 VKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREA 296
              P V+    E + + GL  EG+FR++G    V+Q R + ++    +  K   +C   A
Sbjct: 59  ---PAVVWNIVEYLTQHGLTQEGLFRVNGNVKVVEQLRLKFESGVPVELGKDGDVC--SA 113

Query: 297 AVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALM 356
           A +LK F RELP SL      P FI L + G +  VQ  +L  ++  LPD +    + L 
Sbjct: 114 ASLLKLFLRELPDSLITSALQPRFIQLFQDGRN-DVQESSLRDLIKELPDTHYCLLKYLC 172

Query: 357 TFFNKVIANESKNRMSLWNISTVMAPNLFFSRSKHSDYEELLLANTAAHIIRLMLKYQKI 416
            F  KV  +  +NRM++ N++TV  PN F         +E  L N    I+  +L+    
Sbjct: 173 QFLTKVAKHHVQNRMNVHNLATVFGPNCFHVPPGLEGMKEQDLCN---KIMAKILENYNT 229

Query: 417 LWKVPSFLITQVRRMNEATMLLKKQL--PSVRKLLRRKTLERETASPKTSKVLQKSPSAR 474
           L++V       +R  N A +++ K++   +   +L  + LER+   P     + KS S  
Sbjct: 230 LFEVEYTENDHLRCENLARLIIVKEVYYKNSLPILLTRGLERDMPKPPPKTKIPKSRS-- 287

Query: 475 RMSDVPEGVIRVHAPLLSKVSMAIQLNNQTKAKDILAKFQYENRILHWQRAALSFLNGKW 534
                 EG I+ H  L  ++S  I          +  +  Y    L    +A   ++ K 
Sbjct: 288 ------EGSIQAHRVLQPELSDGI--------PQLSLRLSYRKACLEDMNSAEGAISAKL 333

Query: 535 VKKEREE 541
           V   +E+
Sbjct: 334 VPSSQED 340


>gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens]
          Length = 1271

 Score = 90.5 bits (223), Expect = 4e-18
 Identities = 74/270 (27%), Positives = 122/270 (45%), Gaps = 12/270 (4%)

Query: 125  EELSFEVSYSEMVTEALKRNKLKKSEIKKEDYVLTKFNVQKTRFGLTEAGDLSAEDMKKI 184
            EE   E+  S+ +          K++I KED   T   + K +  L        +  + +
Sbjct: 960  EEFEIELEGSQTLRILCYEKCYNKTKIPKEDGESTDRLMGKGQVQLDPQALQDRDWQRTV 1019

Query: 185  RHLSLIE--LTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVPLV 242
              ++ IE  L+  F++    LKR  + K      G+FGV + V+   +R K     VP +
Sbjct: 1020 IAMNGIEVKLSVKFNSREFSLKRMPSRK----QTGVFGVKIAVVTKRERSK-----VPYI 1070

Query: 243  LQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAAVMLKA 302
            +++  E++E  G+E  GI+R+SG    ++  +   D           +M     A  LK 
Sbjct: 1071 VRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDVNNKDVSVMMSEMDVNAIAGTLKL 1130

Query: 303  FFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFNKV 362
            +FRELP  LF  E+ P F   +     V  +   L+L+ ++LP+AN      L+    +V
Sbjct: 1131 YFRELPEPLFTDEFYPNFAEGIALSDPVAKESCMLNLL-LSLPEANLLTFLFLLDHLKRV 1189

Query: 363  IANESKNRMSLWNISTVMAPNLFFSRSKHS 392
               E+ N+MSL N++TV  P L     K S
Sbjct: 1190 AEKEAVNKMSLHNLATVFGPTLLRPSEKES 1219


>gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens]
          Length = 1227

 Score = 88.2 bits (217), Expect = 2e-17
 Identities = 60/203 (29%), Positives = 98/203 (48%), Gaps = 10/203 (4%)

Query: 190  IELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVPLVLQKFFEK 249
            ++L+  F++    LKR  + K      G+FGV + V+   +R K     VP ++++  E+
Sbjct: 983  VKLSVKFNSREFSLKRMPSRK----QTGVFGVKIAVVTKRERSK-----VPYIVRQCVEE 1033

Query: 250  VEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAAVMLKAFFRELPT 309
            +E  G+E  GI+R+SG    ++  +   D           +M     A  LK +FRELP 
Sbjct: 1034 IERRGMEEVGIYRVSGVATDIQALKAAFDVNNKDVSVMMSEMDVNAIAGTLKLYFRELPE 1093

Query: 310  SLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFNKVIANESKN 369
             LF  E+ P F   +     V  +   L+L+ ++LP+AN      L+    +V   E+ N
Sbjct: 1094 PLFTDEFYPNFAEGIALSDPVAKESCMLNLL-LSLPEANLLTFLFLLDHLKRVAEKEAVN 1152

Query: 370  RMSLWNISTVMAPNLFFSRSKHS 392
            +MSL N++TV  P L     K S
Sbjct: 1153 KMSLHNLATVFGPTLLRPSEKES 1175


>gi|188497642 ARHGAP15 [Homo sapiens]
          Length = 475

 Score = 84.0 bits (206), Expect = 3e-16
 Identities = 54/181 (29%), Positives = 94/181 (51%), Gaps = 8/181 (4%)

Query: 239 VPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYR--EELDAKFNADKFKWDKMCHREA 296
           VP  +++  E VE+ GL+ +GI+R+SG  A +++ R     + K N D  +W+ +     
Sbjct: 294 VPWFVKQCIEAVEKRGLDVDGIYRVSGNLATIQKLRFIVNQEEKLNLDDSQWEDIHVVTG 353

Query: 297 AVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALM 356
           A  LK FFRELP  LFP  +   F+  +++  +   + +A+  +V  LP  NRD  + L 
Sbjct: 354 A--LKMFFRELPEPLFPYSFFEQFVEAIKKQDN-NTRIEAVKSLVQKLPPPNRDTMKVLF 410

Query: 357 TFFNKVIANESKNRMSLWNISTVMAPNLFFSRSKHSDYE-ELLLANTAAHIIRLMLKYQK 415
               K++A  SKN MS  ++  V  P L  + ++  +    ++  N  A +  ++ +Y K
Sbjct: 411 GHLTKIVAKASKNLMSTQSLGIVFGPTLLRAENETGNMAIHMVYQNQIAEL--MLSEYSK 468

Query: 416 I 416
           I
Sbjct: 469 I 469


>gi|229094128 active breakpoint cluster region-related  protein
           isoform c [Homo sapiens]
          Length = 813

 Score = 83.6 bits (205), Expect = 4e-16
 Identities = 58/195 (29%), Positives = 93/195 (47%), Gaps = 10/195 (5%)

Query: 190 IELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVPLVLQKFFEK 249
           +E +  F +  + LKR  ++K      G+FGV ++V+   +R K     VP ++++  E+
Sbjct: 574 VEFSMKFTSRDMSLKRTPSKK----QTGVFGVKISVVTKRERSK-----VPYIVRQCVEE 624

Query: 250 VEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAAVMLKAFFRELPT 309
           VE+ G+E  GI+R+SG    ++  +   DA           M     A  LK +FRELP 
Sbjct: 625 VEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDMDINAIAGTLKLYFRELPE 684

Query: 310 SLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFNKVIANESKN 369
            L      PAF+  +        +   +HL+  +LPD N      L+    +V   E  N
Sbjct: 685 PLLTDRLYPAFMEGIALSDPAAKENCMMHLL-RSLPDPNLITFLFLLEHLKRVAEKEPIN 743

Query: 370 RMSLWNISTVMAPNL 384
           +MSL N++TV  P L
Sbjct: 744 KMSLHNLATVFGPTL 758


>gi|33188433 deleted in liver cancer 1 isoform 1 [Homo sapiens]
          Length = 1528

 Score = 83.6 bits (205), Expect = 4e-16
 Identities = 61/219 (27%), Positives = 106/219 (48%), Gaps = 18/219 (8%)

Query: 177  SAEDMKKIRHLSLIELTAFFDAFGIQLKRN---------KTEKVKG-RDNGIFGVPLTVL 226
            S   M  ++  SL++LTA  + +    K           K  KV   +D  +FGVPLTV 
Sbjct: 1024 SVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVN 1083

Query: 227  LDGDRKKDPGVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKF 286
            +     +  G  +P  +Q+    +    L+  G+FR SG  ++++  R+  +     D  
Sbjct: 1084 V-----QRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAI--DCV 1136

Query: 287  KWDKMCHREAAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPD 346
             ++     + A MLK +FR+LP  L   +    F+ + +  P  + + QA+   +M LPD
Sbjct: 1137 NYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQ-RLQAIKAAIMLLPD 1195

Query: 347  ANRDAAQALMTFFNKVIANESKNRMSLWNISTVMAPNLF 385
             NR+  Q L+ F + V A   +N+M+  N++  +AP+LF
Sbjct: 1196 ENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLF 1234



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 40/156 (25%), Positives = 65/156 (41%), Gaps = 20/156 (12%)

Query: 52  SMPDDASLNSTTLSDASQDKEGSFAVPRSDSVAILETIPVLPVHSNGSPEPGQPVQNAI- 110
           S P D      TL D S+ +E S       SV  L +   LP H+  S +   P  N++ 
Sbjct: 570 SHPKDGPSPGGTLMDLSERQEVS-------SVRSLSSTGSLPSHAPPSEDAATPRTNSVI 622

Query: 111 ----------SDDDFLEKNIPPEAEELSFEVSYSEMVTEALKRNKLKKSEIKKEDYVLTK 160
                     +DD F     P E    SF +   E   ++  R+ LK+ E  K       
Sbjct: 623 SVCSSSNLAGNDDSFGSLPSPKELSSFSFSMKGHEKTAKSKTRSLLKRMESLKLKSSHHS 682

Query: 161 FNVQKTRFGLTEAGDLSAE--DMKKIRHLSLIELTA 194
            +   ++ GL  +G +  E  D +K++ L+ +E++A
Sbjct: 683 KHKAPSKLGLIISGPILQEGMDEEKLKQLNCVEISA 718


>gi|33188437 deleted in liver cancer 1 isoform 2 [Homo sapiens]
          Length = 1091

 Score = 83.6 bits (205), Expect = 4e-16
 Identities = 61/219 (27%), Positives = 106/219 (48%), Gaps = 18/219 (8%)

Query: 177 SAEDMKKIRHLSLIELTAFFDAFGIQLKRN---------KTEKVKG-RDNGIFGVPLTVL 226
           S   M  ++  SL++LTA  + +    K           K  KV   +D  +FGVPLTV 
Sbjct: 587 SVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVN 646

Query: 227 LDGDRKKDPGVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKF 286
           +     +  G  +P  +Q+    +    L+  G+FR SG  ++++  R+  +     D  
Sbjct: 647 V-----QRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAI--DCV 699

Query: 287 KWDKMCHREAAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPD 346
            ++     + A MLK +FR+LP  L   +    F+ + +  P  + + QA+   +M LPD
Sbjct: 700 NYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQ-RLQAIKAAIMLLPD 758

Query: 347 ANRDAAQALMTFFNKVIANESKNRMSLWNISTVMAPNLF 385
            NR+  Q L+ F + V A   +N+M+  N++  +AP+LF
Sbjct: 759 ENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLF 797



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 40/156 (25%), Positives = 65/156 (41%), Gaps = 20/156 (12%)

Query: 52  SMPDDASLNSTTLSDASQDKEGSFAVPRSDSVAILETIPVLPVHSNGSPEPGQPVQNAI- 110
           S P D      TL D S+ +E S       SV  L +   LP H+  S +   P  N++ 
Sbjct: 133 SHPKDGPSPGGTLMDLSERQEVS-------SVRSLSSTGSLPSHAPPSEDAATPRTNSVI 185

Query: 111 ----------SDDDFLEKNIPPEAEELSFEVSYSEMVTEALKRNKLKKSEIKKEDYVLTK 160
                     +DD F     P E    SF +   E   ++  R+ LK+ E  K       
Sbjct: 186 SVCSSSNLAGNDDSFGSLPSPKELSSFSFSMKGHEKTAKSKTRSLLKRMESLKLKSSHHS 245

Query: 161 FNVQKTRFGLTEAGDLSAE--DMKKIRHLSLIELTA 194
            +   ++ GL  +G +  E  D +K++ L+ +E++A
Sbjct: 246 KHKAPSKLGLIISGPILQEGMDEEKLKQLNCVEISA 281


>gi|38679957 active breakpoint cluster region-related  protein
           isoform a [Homo sapiens]
          Length = 859

 Score = 83.6 bits (205), Expect = 4e-16
 Identities = 58/195 (29%), Positives = 93/195 (47%), Gaps = 10/195 (5%)

Query: 190 IELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVPLVLQKFFEK 249
           +E +  F +  + LKR  ++K      G+FGV ++V+   +R K     VP ++++  E+
Sbjct: 620 VEFSMKFTSRDMSLKRTPSKK----QTGVFGVKISVVTKRERSK-----VPYIVRQCVEE 670

Query: 250 VEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAAVMLKAFFRELPT 309
           VE+ G+E  GI+R+SG    ++  +   DA           M     A  LK +FRELP 
Sbjct: 671 VEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDMDINAIAGTLKLYFRELPE 730

Query: 310 SLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFNKVIANESKN 369
            L      PAF+  +        +   +HL+  +LPD N      L+    +V   E  N
Sbjct: 731 PLLTDRLYPAFMEGIALSDPAAKENCMMHLL-RSLPDPNLITFLFLLEHLKRVAEKEPIN 789

Query: 370 RMSLWNISTVMAPNL 384
           +MSL N++TV  P L
Sbjct: 790 KMSLHNLATVFGPTL 804


>gi|38679954 active breakpoint cluster region-related  protein
           isoform b [Homo sapiens]
          Length = 822

 Score = 83.6 bits (205), Expect = 4e-16
 Identities = 58/195 (29%), Positives = 93/195 (47%), Gaps = 10/195 (5%)

Query: 190 IELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVPLVLQKFFEK 249
           +E +  F +  + LKR  ++K      G+FGV ++V+   +R K     VP ++++  E+
Sbjct: 583 VEFSMKFTSRDMSLKRTPSKK----QTGVFGVKISVVTKRERSK-----VPYIVRQCVEE 633

Query: 250 VEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAAVMLKAFFRELPT 309
           VE+ G+E  GI+R+SG    ++  +   DA           M     A  LK +FRELP 
Sbjct: 634 VEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDMDINAIAGTLKLYFRELPE 693

Query: 310 SLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFNKVIANESKN 369
            L      PAF+  +        +   +HL+  +LPD N      L+    +V   E  N
Sbjct: 694 PLLTDRLYPAFMEGIALSDPAAKENCMMHLL-RSLPDPNLITFLFLLEHLKRVAEKEPIN 752

Query: 370 RMSLWNISTVMAPNL 384
           +MSL N++TV  P L
Sbjct: 753 KMSLHNLATVFGPTL 767


>gi|26986534 Rho GTPase activating protein 12 [Homo sapiens]
          Length = 846

 Score = 80.1 bits (196), Expect = 5e-15
 Identities = 51/148 (34%), Positives = 80/148 (54%), Gaps = 6/148 (4%)

Query: 239 VPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREEL--DAKFNADKFKWDKMCHREA 296
           VP  ++   E VEE GL+ +GI+R+SG  A +++ R  +  D K + +  KW+ +     
Sbjct: 669 VPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKLRFAVNHDEKLDLNDSKWEDIHVITG 728

Query: 297 AVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALM 356
           A  LK FFRELP  LF   +   F++ +++ P  +V   A+  ++  LP  N+D  Q L 
Sbjct: 729 A--LKMFFRELPEPLFTFNHFNDFVNAIKQEPRQRVA--AVKDLIRQLPKPNQDTMQILF 784

Query: 357 TFFNKVIANESKNRMSLWNISTVMAPNL 384
               +VI N  KNRM+  +I+ V  P L
Sbjct: 785 RHLRRVIENGEKNRMTYQSIAIVFGPTL 812


>gi|41281907 StAR-related lipid transfer (START) domain containing
           13 isoform beta [Homo sapiens]
          Length = 1105

 Score = 79.7 bits (195), Expect = 6e-15
 Identities = 56/219 (25%), Positives = 105/219 (47%), Gaps = 18/219 (8%)

Query: 177 SAEDMKKIRHLSLIELTAFFDAFGIQLKRNKTEKVKG----------RDNGIFGVPLTVL 226
           +A  +  ++  SL+ LTA  +   +  K   T  V            +D  +FGVPL V 
Sbjct: 601 TASQLSLLQRFSLLRLTAIMEKHSMSNKHGWTWSVPKFMKRMKVPDYKDKAVFGVPLIVH 660

Query: 227 LDGDRKKDPGVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKF 286
           +     +  G  +P  +Q+    +  + L+  G+FR SG  +++   R+ ++  F  +  
Sbjct: 661 V-----QRTGQPLPQSIQQALRYLRSNCLDQVGLFRKSGVKSRIHALRQ-MNENF-PENV 713

Query: 287 KWDKMCHREAAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPD 346
            ++     + A M+K FFR+LP  LF  +    F+ + +     + + QA+   ++ L D
Sbjct: 714 NYEDQSAYDVADMVKQFFRDLPEPLFTNKLSETFLHIYQYVSKEQ-RLQAVQAAILLLAD 772

Query: 347 ANRDAAQALMTFFNKVIANESKNRMSLWNISTVMAPNLF 385
            NR+  Q L+ F N V+    +N+M+  N++  +AP+LF
Sbjct: 773 ENREVLQTLLCFLNDVVNLVEENQMTPMNLAVCLAPSLF 811


>gi|16445031 StAR-related lipid transfer (START) domain containing
           13 isoform gamma [Homo sapiens]
          Length = 995

 Score = 79.7 bits (195), Expect = 6e-15
 Identities = 56/219 (25%), Positives = 105/219 (47%), Gaps = 18/219 (8%)

Query: 177 SAEDMKKIRHLSLIELTAFFDAFGIQLKRNKTEKVKG----------RDNGIFGVPLTVL 226
           +A  +  ++  SL+ LTA  +   +  K   T  V            +D  +FGVPL V 
Sbjct: 491 TASQLSLLQRFSLLRLTAIMEKHSMSNKHGWTWSVPKFMKRMKVPDYKDKAVFGVPLIVH 550

Query: 227 LDGDRKKDPGVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKF 286
           +     +  G  +P  +Q+    +  + L+  G+FR SG  +++   R+ ++  F  +  
Sbjct: 551 V-----QRTGQPLPQSIQQALRYLRSNCLDQVGLFRKSGVKSRIHALRQ-MNENF-PENV 603

Query: 287 KWDKMCHREAAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPD 346
            ++     + A M+K FFR+LP  LF  +    F+ + +     + + QA+   ++ L D
Sbjct: 604 NYEDQSAYDVADMVKQFFRDLPEPLFTNKLSETFLHIYQYVSKEQ-RLQAVQAAILLLAD 662

Query: 347 ANRDAAQALMTFFNKVIANESKNRMSLWNISTVMAPNLF 385
            NR+  Q L+ F N V+    +N+M+  N++  +AP+LF
Sbjct: 663 ENREVLQTLLCFLNDVVNLVEENQMTPMNLAVCLAPSLF 701


>gi|41281898 StAR-related lipid transfer (START) domain containing
           13 isoform alpha [Homo sapiens]
          Length = 1113

 Score = 79.7 bits (195), Expect = 6e-15
 Identities = 56/219 (25%), Positives = 105/219 (47%), Gaps = 18/219 (8%)

Query: 177 SAEDMKKIRHLSLIELTAFFDAFGIQLKRNKTEKVKG----------RDNGIFGVPLTVL 226
           +A  +  ++  SL+ LTA  +   +  K   T  V            +D  +FGVPL V 
Sbjct: 609 TASQLSLLQRFSLLRLTAIMEKHSMSNKHGWTWSVPKFMKRMKVPDYKDKAVFGVPLIVH 668

Query: 227 LDGDRKKDPGVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKF 286
           +     +  G  +P  +Q+    +  + L+  G+FR SG  +++   R+ ++  F  +  
Sbjct: 669 V-----QRTGQPLPQSIQQALRYLRSNCLDQVGLFRKSGVKSRIHALRQ-MNENF-PENV 721

Query: 287 KWDKMCHREAAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPD 346
            ++     + A M+K FFR+LP  LF  +    F+ + +     + + QA+   ++ L D
Sbjct: 722 NYEDQSAYDVADMVKQFFRDLPEPLFTNKLSETFLHIYQYVSKEQ-RLQAVQAAILLLAD 780

Query: 347 ANRDAAQALMTFFNKVIANESKNRMSLWNISTVMAPNLF 385
            NR+  Q L+ F N V+    +N+M+  N++  +AP+LF
Sbjct: 781 ENREVLQTLLCFLNDVVNLVEENQMTPMNLAVCLAPSLF 819


>gi|226693398 Rho GTPase activating protein 27 isoform b [Homo
           sapiens]
          Length = 521

 Score = 79.0 bits (193), Expect = 1e-14
 Identities = 50/169 (29%), Positives = 89/169 (52%), Gaps = 10/169 (5%)

Query: 218 IFGVPLTVLLDGDRKKDPGVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVK--QYRE 275
           +FG  L  L + +R +     VP  +Q+    VE  GL+ +G++R+SG  A ++  +Y+ 
Sbjct: 326 VFGCALAALCERERSR-----VPRFVQQCIRAVEARGLDIDGLYRISGNLATIQKLRYKV 380

Query: 276 ELDAKFNADKFKWDKMCHREAAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQ 335
           + D + + D  +W+ +     A  LK FFRELP  LFP  +   FI+ ++     + + +
Sbjct: 381 DHDERLDLDDGRWEDVHVITGA--LKLFFRELPEPLFPFSHFRQFIAAIKLQDQAR-RSR 437

Query: 336 ALHLMVMALPDANRDAAQALMTFFNKVIANESKNRMSLWNISTVMAPNL 384
            +  +V +LP  N D  + L     +VI +  +NRMS+ +++ V  P L
Sbjct: 438 CVRDLVRSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTL 486


>gi|40548322 Rho GTPase activating protein 27 isoform a [Homo
           sapiens]
          Length = 548

 Score = 79.0 bits (193), Expect = 1e-14
 Identities = 50/169 (29%), Positives = 89/169 (52%), Gaps = 10/169 (5%)

Query: 218 IFGVPLTVLLDGDRKKDPGVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVK--QYRE 275
           +FG  L  L + +R +     VP  +Q+    VE  GL+ +G++R+SG  A ++  +Y+ 
Sbjct: 353 VFGCALAALCERERSR-----VPRFVQQCIRAVEARGLDIDGLYRISGNLATIQKLRYKV 407

Query: 276 ELDAKFNADKFKWDKMCHREAAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQ 335
           + D + + D  +W+ +     A  LK FFRELP  LFP  +   FI+ ++     + + +
Sbjct: 408 DHDERLDLDDGRWEDVHVITGA--LKLFFRELPEPLFPFSHFRQFIAAIKLQDQAR-RSR 464

Query: 336 ALHLMVMALPDANRDAAQALMTFFNKVIANESKNRMSLWNISTVMAPNL 384
            +  +V +LP  N D  + L     +VI +  +NRMS+ +++ V  P L
Sbjct: 465 CVRDLVRSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTL 513


>gi|7382480 Rho GTPase activating protein 6 isoform 4 [Homo sapiens]
          Length = 771

 Score = 76.3 bits (186), Expect = 7e-14
 Identities = 69/247 (27%), Positives = 114/247 (46%), Gaps = 28/247 (11%)

Query: 238 KVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAA 297
           +VP ++    + +E+ GL++ GIFR+     +V+Q REE D     D    ++    + A
Sbjct: 206 QVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDR--GIDVSLEEEHSVHDVA 263

Query: 298 VMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMT 357
            +LK F R++P  L   E   AFI+ +   P  + Q   L L++  LP  N D    L+ 
Sbjct: 264 ALLKEFLRDMPDPLLTRELYTAFINTLLLEP--EEQLGTLQLLIYLLPPCNCDTLHRLLQ 321

Query: 358 FFNKVIA----NESK-------NRMSLWNISTVMAPNLFFSRSKHSDYEELLLANTAAH- 405
           F + V      N SK       N+M+  N++T+  PNL   + K SD E  + ++  A  
Sbjct: 322 FLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNL-LHKQKSSDKEFSVQSSARAEE 380

Query: 406 ------IIRLMLKYQKILWKVPSFLITQVRRMNEATMLLKKQLPSVRKLLRRKTLERETA 459
                 +++ M++  + L+ VP  L  +V        LL+     V  LLRRK  +  + 
Sbjct: 381 STAIIAVVQKMIENYEALFMVPPDLQNEV-----LISLLETDPDVVDYLLRRKASQSSSP 435

Query: 460 SPKTSKV 466
               S+V
Sbjct: 436 DMLQSEV 442


>gi|95091988 Rho GTPase activating protein 6 isoform 3 [Homo
           sapiens]
          Length = 765

 Score = 76.3 bits (186), Expect = 7e-14
 Identities = 69/247 (27%), Positives = 114/247 (46%), Gaps = 28/247 (11%)

Query: 238 KVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAA 297
           +VP ++    + +E+ GL++ GIFR+     +V+Q REE D     D    ++    + A
Sbjct: 409 QVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDR--GIDVSLEEEHSVHDVA 466

Query: 298 VMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMT 357
            +LK F R++P  L   E   AFI+ +   P  + Q   L L++  LP  N D    L+ 
Sbjct: 467 ALLKEFLRDMPDPLLTRELYTAFINTLLLEP--EEQLGTLQLLIYLLPPCNCDTLHRLLQ 524

Query: 358 FFNKVIA----NESK-------NRMSLWNISTVMAPNLFFSRSKHSDYEELLLANTAAH- 405
           F + V      N SK       N+M+  N++T+  PNL   + K SD E  + ++  A  
Sbjct: 525 FLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNL-LHKQKSSDKEFSVQSSARAEE 583

Query: 406 ------IIRLMLKYQKILWKVPSFLITQVRRMNEATMLLKKQLPSVRKLLRRKTLERETA 459
                 +++ M++  + L+ VP  L  +V        LL+     V  LLRRK  +  + 
Sbjct: 584 STAIIAVVQKMIENYEALFMVPPDLQNEV-----LISLLETDPDVVDYLLRRKASQSSSP 638

Query: 460 SPKTSKV 466
               S+V
Sbjct: 639 DMLQSEV 645


>gi|95091875 Rho GTPase activating protein 6 isoform 1 [Homo
           sapiens]
          Length = 974

 Score = 76.3 bits (186), Expect = 7e-14
 Identities = 69/247 (27%), Positives = 114/247 (46%), Gaps = 28/247 (11%)

Query: 238 KVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAA 297
           +VP ++    + +E+ GL++ GIFR+     +V+Q REE D     D    ++    + A
Sbjct: 409 QVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDR--GIDVSLEEEHSVHDVA 466

Query: 298 VMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMT 357
            +LK F R++P  L   E   AFI+ +   P  + Q   L L++  LP  N D    L+ 
Sbjct: 467 ALLKEFLRDMPDPLLTRELYTAFINTLLLEP--EEQLGTLQLLIYLLPPCNCDTLHRLLQ 524

Query: 358 FFNKVIA----NESK-------NRMSLWNISTVMAPNLFFSRSKHSDYEELLLANTAAH- 405
           F + V      N SK       N+M+  N++T+  PNL   + K SD E  + ++  A  
Sbjct: 525 FLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNL-LHKQKSSDKEFSVQSSARAEE 583

Query: 406 ------IIRLMLKYQKILWKVPSFLITQVRRMNEATMLLKKQLPSVRKLLRRKTLERETA 459
                 +++ M++  + L+ VP  L  +V        LL+     V  LLRRK  +  + 
Sbjct: 584 STAIIAVVQKMIENYEALFMVPPDLQNEV-----LISLLETDPDVVDYLLRRKASQSSSP 638

Query: 460 SPKTSKV 466
               S+V
Sbjct: 639 DMLQSEV 645


>gi|5803145 ralA binding protein 1 [Homo sapiens]
          Length = 655

 Score = 75.9 bits (185), Expect = 9e-14
 Identities = 48/170 (28%), Positives = 89/170 (52%), Gaps = 5/170 (2%)

Query: 218 IFGVPLTVLLDGDRKKDPGVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREEL 277
           IFG+PL   ++     D G+++P V ++  + VE+ G++ EGI+R+SG  +KV + +   
Sbjct: 189 IFGIPLADAVERTMMYD-GIRLPAVFRECIDYVEKYGMKCEGIYRVSGIKSKVDELKAAY 247

Query: 278 DAKFNADKFKWDKMCHREAAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQAL 337
           D + + +   ++       A +LK + R+LP +L   E +P F     R    + + Q  
Sbjct: 248 DREESTNLEDYEP---NTVASLLKQYLRDLPENLLTKELMPRFEEACGRTTETE-KVQEF 303

Query: 338 HLMVMALPDANRDAAQALMTFFNKVIANESKNRMSLWNISTVMAPNLFFS 387
             ++  LP+ N      L+   + VIA E + +M++ NIS V++P +  S
Sbjct: 304 QRLLKELPECNYLLISWLIVHMDHVIAKELETKMNIQNISIVLSPTVQIS 353


>gi|215820652 StAR-related lipid transfer (START) domain containing
           8 isoform b [Homo sapiens]
          Length = 1023

 Score = 75.9 bits (185), Expect = 9e-14
 Identities = 54/210 (25%), Positives = 103/210 (49%), Gaps = 23/210 (10%)

Query: 188 SLIELTAFFDAFGIQ------------LKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDP 235
           SL+ LTAF + + +             ++RNKT   +G+   +FGVP  + +     +  
Sbjct: 529 SLLRLTAFMEKYTVPHKQGWVWSMPKFMRRNKTPDYRGQH--VFGVPPLIHV-----QRT 581

Query: 236 GVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHRE 295
           G  +P  +Q+    +    L+  GIFR SG  ++++  R+  +   + D   ++     +
Sbjct: 582 GQPLPQSIQQAMRYLRSQCLDQVGIFRKSGVKSRIQNLRQMNET--SPDNVCYEGQSAYD 639

Query: 296 AAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQAL 355
            A +LK +FR+LP  +F  +    F+ + +  P  +    A     + LPD NR+  Q L
Sbjct: 640 VADLLKQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQ-WLAAAQAATLLLPDENREVLQTL 698

Query: 356 MTFFNKVIANESKNRMSLWNISTVMAPNLF 385
           + F +  IA+  +N+M+  N++  +AP++F
Sbjct: 699 LYFLSD-IASAEENQMTAGNLAVCLAPSIF 727


>gi|215820650 StAR-related lipid transfer (START) domain containing
           8 isoform a [Homo sapiens]
          Length = 1103

 Score = 75.9 bits (185), Expect = 9e-14
 Identities = 54/210 (25%), Positives = 103/210 (49%), Gaps = 23/210 (10%)

Query: 188 SLIELTAFFDAFGIQ------------LKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDP 235
           SL+ LTAF + + +             ++RNKT   +G+   +FGVP  + +     +  
Sbjct: 609 SLLRLTAFMEKYTVPHKQGWVWSMPKFMRRNKTPDYRGQH--VFGVPPLIHV-----QRT 661

Query: 236 GVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHRE 295
           G  +P  +Q+    +    L+  GIFR SG  ++++  R+  +   + D   ++     +
Sbjct: 662 GQPLPQSIQQAMRYLRSQCLDQVGIFRKSGVKSRIQNLRQMNET--SPDNVCYEGQSAYD 719

Query: 296 AAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQAL 355
            A +LK +FR+LP  +F  +    F+ + +  P  +    A     + LPD NR+  Q L
Sbjct: 720 VADLLKQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQ-WLAAAQAATLLLPDENREVLQTL 778

Query: 356 MTFFNKVIANESKNRMSLWNISTVMAPNLF 385
           + F +  IA+  +N+M+  N++  +AP++F
Sbjct: 779 LYFLSD-IASAEENQMTAGNLAVCLAPSIF 807


>gi|31543659 StAR-related lipid transfer (START) domain containing 8
           isoform b [Homo sapiens]
          Length = 1023

 Score = 75.9 bits (185), Expect = 9e-14
 Identities = 54/210 (25%), Positives = 103/210 (49%), Gaps = 23/210 (10%)

Query: 188 SLIELTAFFDAFGIQ------------LKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDP 235
           SL+ LTAF + + +             ++RNKT   +G+   +FGVP  + +     +  
Sbjct: 529 SLLRLTAFMEKYTVPHKQGWVWSMPKFMRRNKTPDYRGQH--VFGVPPLIHV-----QRT 581

Query: 236 GVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHRE 295
           G  +P  +Q+    +    L+  GIFR SG  ++++  R+  +   + D   ++     +
Sbjct: 582 GQPLPQSIQQAMRYLRSQCLDQVGIFRKSGVKSRIQNLRQMNET--SPDNVCYEGQSAYD 639

Query: 296 AAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQAL 355
            A +LK +FR+LP  +F  +    F+ + +  P  +    A     + LPD NR+  Q L
Sbjct: 640 VADLLKQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQ-WLAAAQAATLLLPDENREVLQTL 698

Query: 356 MTFFNKVIANESKNRMSLWNISTVMAPNLF 385
           + F +  IA+  +N+M+  N++  +AP++F
Sbjct: 699 LYFLSD-IASAEENQMTAGNLAVCLAPSIF 727


>gi|156119615 myosin IXA [Homo sapiens]
          Length = 2548

 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 83/328 (25%), Positives = 139/328 (42%), Gaps = 40/328 (12%)

Query: 219  FGVPLTVLLDGDRKKDPGVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELD 278
            FGV L+ L   DR       VPLV++K    +E  GL +EGI+R SG T K+K+ R+ LD
Sbjct: 2061 FGVELSRLTSEDRT------VPLVVEKLINYIEMHGLYTEGIYRKSGSTNKIKELRQGLD 2114

Query: 279  AKFNADKFKWDKMCHREAAVMLKAFFRELPTSLFPVEYIPAFI---SLMERGPHVKVQFQ 335
               +A+    D       A + K + R+LP  L   E    F+    L ER    K   +
Sbjct: 2115 T--DAESVNLDDYNIHVIASVFKQWLRDLPNPLMTFELYEEFLRAMGLQER----KETIR 2168

Query: 336  ALHLMVMALPDANRDAAQALMTFFNKVIANESKNRMSLWNISTVMAPNLFFSRSKHSDYE 395
             ++ ++  L   + +  + L+    ++   E  NRMS   ++ V AP +          +
Sbjct: 2169 GVYSVIDQLSRTHLNTLERLIFHLVRIALQEDTNRMSANALAIVFAPCILRCPDTTDPLQ 2228

Query: 396  ELLLANTAAHIIRLMLKYQKILWKVPSFLITQVRRMNEATMLLKKQLPSVRKLLRRKTLE 455
             +   +     + L++  Q   +K     +  +  +  A    K +L  +R+ + +  + 
Sbjct: 2229 SVQDISKTTTCVELIVVEQMNKYKA---RLKDISSLEFAENKAKTRLSLIRRSMGKGRIR 2285

Query: 456  RETASPKTSKVLQKSPSARRMSDVPEGVIRVHAPLLSKVSMAIQLNNQTKAKDILAKFQY 515
            R      +S V+ + PS   +SDV E        L S+ +M   +  Q +     A  Q 
Sbjct: 2286 RGNYPGPSSPVVVRLPS---VSDVSE------ETLTSEAAMETDITEQQQ-----AAMQQ 2331

Query: 516  ENRILHWQRAALSFLNGKWVKKEREEST 543
            E R+L  Q   L        +KE+EE T
Sbjct: 2332 EERVLTEQIENL--------QKEKEELT 2351


>gi|150417981 glucocorticoid receptor DNA binding factor 1 [Homo
            sapiens]
          Length = 1499

 Score = 73.2 bits (178), Expect = 6e-13
 Identities = 58/201 (28%), Positives = 95/201 (47%), Gaps = 16/201 (7%)

Query: 215  DNGIFGVPLTVLLDGDRKKDPGVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYR 274
            ++  FGVPLT ++       P   +P+ +++  E +E +GL +EGI+R+SG  ++++  +
Sbjct: 1243 ESNYFGVPLTTVVT------PEKPIPIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQ 1296

Query: 275  EELDAKFNADKFKWDKMCHREAAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQF 334
             + D   N D  + D   +  A  M K+FF ELP  L P       I L+E    +  + 
Sbjct: 1297 RQFDQDHNLDLAEKDFTVNTVAGAM-KSFFSELPDPLVPYN---MQIDLVE-AHKINDRE 1351

Query: 335  QALHLMVMAL---PDANRDAAQALMTFFNKVIANESKNRMSLWNISTVMAPNLFFSRSKH 391
            Q LH +   L   P  N +  + +++  NKV  N   N M+  N+S    P L   R   
Sbjct: 1352 QKLHALKEVLKKFPKENHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTLM--RPDF 1409

Query: 392  SDYEELLLANTAAHIIRLMLK 412
            S  + L    T   II L ++
Sbjct: 1410 STMDALTATRTYQTIIELFIQ 1430


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.132    0.372 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,722,180
Number of Sequences: 37866
Number of extensions: 850713
Number of successful extensions: 3177
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 85
Number of HSP's successfully gapped in prelim test: 48
Number of HSP's that attempted gapping in prelim test: 2905
Number of HSP's gapped (non-prelim): 180
length of query: 563
length of database: 18,247,518
effective HSP length: 107
effective length of query: 456
effective length of database: 14,195,856
effective search space: 6473310336
effective search space used: 6473310336
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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