BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|59710111 Rho GTPase activating protein 28 isoform b [Homo sapiens] (563 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|59710111 Rho GTPase activating protein 28 isoform b [Homo sap... 1106 0.0 gi|59710113 Rho GTPase activating protein 28 isoform a [Homo sap... 1013 0.0 gi|39932589 Rho GTPase activating protein 18 [Homo sapiens] 332 7e-91 gi|239757488 PREDICTED: chromosome 20 open reading frame 95 [Hom... 253 3e-67 gi|239752003 PREDICTED: chromosome 20 open reading frame 95 [Hom... 253 3e-67 gi|239746488 PREDICTED: Rho GTPase-activating protein 18-like [H... 253 3e-67 gi|56119110 family with sequence similarity 13, member A1 isofor... 91 3e-18 gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens] 91 4e-18 gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens] 88 2e-17 gi|188497642 ARHGAP15 [Homo sapiens] 84 3e-16 gi|229094128 active breakpoint cluster region-related protein i... 84 4e-16 gi|33188433 deleted in liver cancer 1 isoform 1 [Homo sapiens] 84 4e-16 gi|33188437 deleted in liver cancer 1 isoform 2 [Homo sapiens] 84 4e-16 gi|38679957 active breakpoint cluster region-related protein is... 84 4e-16 gi|38679954 active breakpoint cluster region-related protein is... 84 4e-16 gi|26986534 Rho GTPase activating protein 12 [Homo sapiens] 80 5e-15 gi|41281907 StAR-related lipid transfer (START) domain containin... 80 6e-15 gi|16445031 StAR-related lipid transfer (START) domain containin... 80 6e-15 gi|41281898 StAR-related lipid transfer (START) domain containin... 80 6e-15 gi|226693398 Rho GTPase activating protein 27 isoform b [Homo sa... 79 1e-14 gi|40548322 Rho GTPase activating protein 27 isoform a [Homo sap... 79 1e-14 gi|7382480 Rho GTPase activating protein 6 isoform 4 [Homo sapiens] 76 7e-14 gi|95091988 Rho GTPase activating protein 6 isoform 3 [Homo sapi... 76 7e-14 gi|95091875 Rho GTPase activating protein 6 isoform 1 [Homo sapi... 76 7e-14 gi|5803145 ralA binding protein 1 [Homo sapiens] 76 9e-14 gi|215820652 StAR-related lipid transfer (START) domain containi... 76 9e-14 gi|215820650 StAR-related lipid transfer (START) domain containi... 76 9e-14 gi|31543659 StAR-related lipid transfer (START) domain containin... 76 9e-14 gi|156119615 myosin IXA [Homo sapiens] 75 2e-13 gi|150417981 glucocorticoid receptor DNA binding factor 1 [Homo ... 73 6e-13 >gi|59710111 Rho GTPase activating protein 28 isoform b [Homo sapiens] Length = 563 Score = 1106 bits (2860), Expect = 0.0 Identities = 563/563 (100%), Positives = 563/563 (100%) Query: 1 MRKKDKQSIRDVRDIFGVSESPPRDTCGNHTNQLDGTKEERELPRVIKTSGSMPDDASLN 60 MRKKDKQSIRDVRDIFGVSESPPRDTCGNHTNQLDGTKEERELPRVIKTSGSMPDDASLN Sbjct: 1 MRKKDKQSIRDVRDIFGVSESPPRDTCGNHTNQLDGTKEERELPRVIKTSGSMPDDASLN 60 Query: 61 STTLSDASQDKEGSFAVPRSDSVAILETIPVLPVHSNGSPEPGQPVQNAISDDDFLEKNI 120 STTLSDASQDKEGSFAVPRSDSVAILETIPVLPVHSNGSPEPGQPVQNAISDDDFLEKNI Sbjct: 61 STTLSDASQDKEGSFAVPRSDSVAILETIPVLPVHSNGSPEPGQPVQNAISDDDFLEKNI 120 Query: 121 PPEAEELSFEVSYSEMVTEALKRNKLKKSEIKKEDYVLTKFNVQKTRFGLTEAGDLSAED 180 PPEAEELSFEVSYSEMVTEALKRNKLKKSEIKKEDYVLTKFNVQKTRFGLTEAGDLSAED Sbjct: 121 PPEAEELSFEVSYSEMVTEALKRNKLKKSEIKKEDYVLTKFNVQKTRFGLTEAGDLSAED 180 Query: 181 MKKIRHLSLIELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVP 240 MKKIRHLSLIELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVP Sbjct: 181 MKKIRHLSLIELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVP 240 Query: 241 LVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAAVML 300 LVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAAVML Sbjct: 241 LVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAAVML 300 Query: 301 KAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFN 360 KAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFN Sbjct: 301 KAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFN 360 Query: 361 KVIANESKNRMSLWNISTVMAPNLFFSRSKHSDYEELLLANTAAHIIRLMLKYQKILWKV 420 KVIANESKNRMSLWNISTVMAPNLFFSRSKHSDYEELLLANTAAHIIRLMLKYQKILWKV Sbjct: 361 KVIANESKNRMSLWNISTVMAPNLFFSRSKHSDYEELLLANTAAHIIRLMLKYQKILWKV 420 Query: 421 PSFLITQVRRMNEATMLLKKQLPSVRKLLRRKTLERETASPKTSKVLQKSPSARRMSDVP 480 PSFLITQVRRMNEATMLLKKQLPSVRKLLRRKTLERETASPKTSKVLQKSPSARRMSDVP Sbjct: 421 PSFLITQVRRMNEATMLLKKQLPSVRKLLRRKTLERETASPKTSKVLQKSPSARRMSDVP 480 Query: 481 EGVIRVHAPLLSKVSMAIQLNNQTKAKDILAKFQYENRILHWQRAALSFLNGKWVKKERE 540 EGVIRVHAPLLSKVSMAIQLNNQTKAKDILAKFQYENRILHWQRAALSFLNGKWVKKERE Sbjct: 481 EGVIRVHAPLLSKVSMAIQLNNQTKAKDILAKFQYENRILHWQRAALSFLNGKWVKKERE 540 Query: 541 ESTETNRSPKHVFLFTIGLDIST 563 ESTETNRSPKHVFLFTIGLDIST Sbjct: 541 ESTETNRSPKHVFLFTIGLDIST 563 >gi|59710113 Rho GTPase activating protein 28 isoform a [Homo sapiens] Length = 570 Score = 1013 bits (2618), Expect = 0.0 Identities = 517/517 (100%), Positives = 517/517 (100%) Query: 1 MRKKDKQSIRDVRDIFGVSESPPRDTCGNHTNQLDGTKEERELPRVIKTSGSMPDDASLN 60 MRKKDKQSIRDVRDIFGVSESPPRDTCGNHTNQLDGTKEERELPRVIKTSGSMPDDASLN Sbjct: 1 MRKKDKQSIRDVRDIFGVSESPPRDTCGNHTNQLDGTKEERELPRVIKTSGSMPDDASLN 60 Query: 61 STTLSDASQDKEGSFAVPRSDSVAILETIPVLPVHSNGSPEPGQPVQNAISDDDFLEKNI 120 STTLSDASQDKEGSFAVPRSDSVAILETIPVLPVHSNGSPEPGQPVQNAISDDDFLEKNI Sbjct: 61 STTLSDASQDKEGSFAVPRSDSVAILETIPVLPVHSNGSPEPGQPVQNAISDDDFLEKNI 120 Query: 121 PPEAEELSFEVSYSEMVTEALKRNKLKKSEIKKEDYVLTKFNVQKTRFGLTEAGDLSAED 180 PPEAEELSFEVSYSEMVTEALKRNKLKKSEIKKEDYVLTKFNVQKTRFGLTEAGDLSAED Sbjct: 121 PPEAEELSFEVSYSEMVTEALKRNKLKKSEIKKEDYVLTKFNVQKTRFGLTEAGDLSAED 180 Query: 181 MKKIRHLSLIELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVP 240 MKKIRHLSLIELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVP Sbjct: 181 MKKIRHLSLIELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVP 240 Query: 241 LVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAAVML 300 LVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAAVML Sbjct: 241 LVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAAVML 300 Query: 301 KAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFN 360 KAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFN Sbjct: 301 KAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFN 360 Query: 361 KVIANESKNRMSLWNISTVMAPNLFFSRSKHSDYEELLLANTAAHIIRLMLKYQKILWKV 420 KVIANESKNRMSLWNISTVMAPNLFFSRSKHSDYEELLLANTAAHIIRLMLKYQKILWKV Sbjct: 361 KVIANESKNRMSLWNISTVMAPNLFFSRSKHSDYEELLLANTAAHIIRLMLKYQKILWKV 420 Query: 421 PSFLITQVRRMNEATMLLKKQLPSVRKLLRRKTLERETASPKTSKVLQKSPSARRMSDVP 480 PSFLITQVRRMNEATMLLKKQLPSVRKLLRRKTLERETASPKTSKVLQKSPSARRMSDVP Sbjct: 421 PSFLITQVRRMNEATMLLKKQLPSVRKLLRRKTLERETASPKTSKVLQKSPSARRMSDVP 480 Query: 481 EGVIRVHAPLLSKVSMAIQLNNQTKAKDILAKFQYEN 517 EGVIRVHAPLLSKVSMAIQLNNQTKAKDILAKFQYEN Sbjct: 481 EGVIRVHAPLLSKVSMAIQLNNQTKAKDILAKFQYEN 517 >gi|39932589 Rho GTPase activating protein 18 [Homo sapiens] Length = 663 Score = 332 bits (850), Expect = 7e-91 Identities = 176/405 (43%), Positives = 259/405 (63%), Gaps = 19/405 (4%) Query: 117 EKNIPPEAE-----ELSFEVSYSEMVTEALKRNKLKKSEIKKEDYVLTKFNVQKTRFGLT 171 EK IPPE +++ EVS++E + +K K + K +D L F + K + G T Sbjct: 215 EKLIPPEETPAPETDINLEVSFAEQALNQKESSKEKIQKSKGDDATLPSFRLPKDKTGTT 274 Query: 172 EAGDLSAEDMKKIRHLSLIELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDR 231 GDL+ +DMKK+ HL+LIELTA +D GI+LK+ K K+K +D+G+F VPLT LL+ D+ Sbjct: 275 RIGDLAPQDMKKVCHLALIELTALYDVLGIELKQQKAVKIKTKDSGLFCVPLTALLEQDQ 334 Query: 232 KKDPGVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKM 291 +K PG+++PL+ QK ++EE GLE+EG+ R+ G ++K +EL+AKF F W+ + Sbjct: 335 RKVPGMRIPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESV 394 Query: 292 CHREAAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDA 351 +AA +LK F RELP L VEY+ AF ++ P K Q QAL+L+V+ LPDANRD Sbjct: 395 KQHDAASLLKLFIRELPQPLLSVEYLKAF-QAVQNLPTKKQQLQALNLLVILLPDANRDT 453 Query: 352 AQALMTFFNKVIANESKNRMSLWNISTVMAPNLFFSRS---KHSDYEELLLANTAAHIIR 408 +AL+ F +VI N+ KN+M++ N++ VMAPNLF + K S+ E ++A A+ + Sbjct: 454 LKALLEFLQRVIDNKEKNKMTVMNVAMVMAPNLFMCHALGLKSSEQREFVMAAGTANTMH 513 Query: 409 LMLKYQKILWKVPSFLITQVRRMNEATMLLKKQLPSVRKLLRRKTLERETASPKTSKVLQ 468 L++KYQK+LW +P F++ QVR+ N T KK +++KLL++ +RE + Sbjct: 514 LLIKYQKLLWTIPKFIVNQVRKQN--TENHKKDKRAMKKLLKKMAYDREK--------YE 563 Query: 469 KSPSARRMSDVPEGVIRVHAPLLSKVSMAIQLNNQTKAKDILAKF 513 K + +DVP+GVIRV AP LSKVSMAIQL + KA D+LA+F Sbjct: 564 KQDKSTNDADVPQGVIRVQAPHLSKVSMAIQLTEELKASDVLARF 608 >gi|239757488 PREDICTED: chromosome 20 open reading frame 95 [Homo sapiens] Length = 622 Score = 253 bits (646), Expect = 3e-67 Identities = 144/354 (40%), Positives = 216/354 (61%), Gaps = 14/354 (3%) Query: 125 EELSFEVSYSEMVTEALKRNKLKKSEIKKEDYV-LTKFNVQKTRFGLTEAGDLSAEDMKK 183 E + + +YSE L+R++ + L KF V K R G+T GDLS +DM+K Sbjct: 173 EAFNMDSAYSEQAAVLLQRSRPSRGGTSAWGKCSLPKFTVPKGRLGVTRIGDLSLQDMRK 232 Query: 184 IRHLSLIELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVPLVL 243 + L+LIELTA D G+ LKR+K K K + +FGVPL LL+ D K P +VPLVL Sbjct: 233 VPSLALIELTALCDILGLDLKRSKAGKWKAAETRLFGVPLDSLLEADHKVLPSTQVPLVL 292 Query: 244 QKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAAVMLKAF 303 Q +E+ GL+ EGI R+ G A+VK ++L+ F A F WD++ H +A+ +LK F Sbjct: 293 QALLSCLEKRGLDMEGILRVPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDASDLLKRF 352 Query: 304 FRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFNKVI 363 R+LPT L EY+PAF +++ P++K + Q LHL+++ LP+ NR+A +AL+ F KV+ Sbjct: 353 IRKLPTPLLTAEYLPAF-AVVPNIPNLKQRLQVLHLLILILPEPNRNALKALLEFLRKVV 411 Query: 364 ANESKNRMSLWNISTVMAPNLFFSRS---KHSDYEELLLANTAAHIIRLMLKYQKILWKV 420 A E N+M+L N+STVMAPNLF + K +E LA AA ++++M+ YQ +LW V Sbjct: 412 AREQHNKMTLRNVSTVMAPNLFLHQGRPPKLPKGKEKQLAEGAAEVVQIMVHYQDLLWTV 471 Query: 421 PSFLITQVRRMNEATMLLKKQL--PSVRKLLRRKTLERE------TASPKTSKV 466 SFL+ QVR++N+++ + QL ++ LRR +R+ A+PK +K+ Sbjct: 472 ASFLVAQVRKLNDSSS-RRPQLCDAGLKTWLRRMHADRDKAGDGLEATPKVAKI 524 >gi|239752003 PREDICTED: chromosome 20 open reading frame 95 [Homo sapiens] Length = 622 Score = 253 bits (646), Expect = 3e-67 Identities = 144/354 (40%), Positives = 216/354 (61%), Gaps = 14/354 (3%) Query: 125 EELSFEVSYSEMVTEALKRNKLKKSEIKKEDYV-LTKFNVQKTRFGLTEAGDLSAEDMKK 183 E + + +YSE L+R++ + L KF V K R G+T GDLS +DM+K Sbjct: 173 EAFNMDSAYSEQAAVLLQRSRPSRGGTSAWGKCSLPKFTVPKGRLGVTRIGDLSLQDMRK 232 Query: 184 IRHLSLIELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVPLVL 243 + L+LIELTA D G+ LKR+K K K + +FGVPL LL+ D K P +VPLVL Sbjct: 233 VPSLALIELTALCDILGLDLKRSKAGKWKAAETRLFGVPLDSLLEADHKVLPSTQVPLVL 292 Query: 244 QKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAAVMLKAF 303 Q +E+ GL+ EGI R+ G A+VK ++L+ F A F WD++ H +A+ +LK F Sbjct: 293 QALLSCLEKRGLDMEGILRVPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDASDLLKRF 352 Query: 304 FRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFNKVI 363 R+LPT L EY+PAF +++ P++K + Q LHL+++ LP+ NR+A +AL+ F KV+ Sbjct: 353 IRKLPTPLLTAEYLPAF-AVVPNIPNLKQRLQVLHLLILILPEPNRNALKALLEFLRKVV 411 Query: 364 ANESKNRMSLWNISTVMAPNLFFSRS---KHSDYEELLLANTAAHIIRLMLKYQKILWKV 420 A E N+M+L N+STVMAPNLF + K +E LA AA ++++M+ YQ +LW V Sbjct: 412 AREQHNKMTLRNVSTVMAPNLFLHQGRPPKLPKGKEKQLAEGAAEVVQIMVHYQDLLWTV 471 Query: 421 PSFLITQVRRMNEATMLLKKQL--PSVRKLLRRKTLERE------TASPKTSKV 466 SFL+ QVR++N+++ + QL ++ LRR +R+ A+PK +K+ Sbjct: 472 ASFLVAQVRKLNDSSS-RRPQLCDAGLKTWLRRMHADRDKAGDGLEATPKVAKI 524 >gi|239746488 PREDICTED: Rho GTPase-activating protein 18-like [Homo sapiens] Length = 622 Score = 253 bits (646), Expect = 3e-67 Identities = 144/354 (40%), Positives = 216/354 (61%), Gaps = 14/354 (3%) Query: 125 EELSFEVSYSEMVTEALKRNKLKKSEIKKEDYV-LTKFNVQKTRFGLTEAGDLSAEDMKK 183 E + + +YSE L+R++ + L KF V K R G+T GDLS +DM+K Sbjct: 173 EAFNMDSAYSEQAAVLLQRSRPSRGGTSAWGKCSLPKFTVPKGRLGVTRIGDLSLQDMRK 232 Query: 184 IRHLSLIELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVPLVL 243 + L+LIELTA D G+ LKR+K K K + +FGVPL LL+ D K P +VPLVL Sbjct: 233 VPSLALIELTALCDILGLDLKRSKAGKWKAAETRLFGVPLDSLLEADHKVLPSTQVPLVL 292 Query: 244 QKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAAVMLKAF 303 Q +E+ GL+ EGI R+ G A+VK ++L+ F A F WD++ H +A+ +LK F Sbjct: 293 QALLSCLEKRGLDMEGILRVPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDASDLLKRF 352 Query: 304 FRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFNKVI 363 R+LPT L EY+PAF +++ P++K + Q LHL+++ LP+ NR+A +AL+ F KV+ Sbjct: 353 IRKLPTPLLTAEYLPAF-AVVPNIPNLKQRLQVLHLLILILPEPNRNALKALLEFLRKVV 411 Query: 364 ANESKNRMSLWNISTVMAPNLFFSRS---KHSDYEELLLANTAAHIIRLMLKYQKILWKV 420 A E N+M+L N+STVMAPNLF + K +E LA AA ++++M+ YQ +LW V Sbjct: 412 AREQHNKMTLRNVSTVMAPNLFLHQGRPPKLPKGKEKQLAEGAAEVVQIMVHYQDLLWTV 471 Query: 421 PSFLITQVRRMNEATMLLKKQL--PSVRKLLRRKTLERE------TASPKTSKV 466 SFL+ QVR++N+++ + QL ++ LRR +R+ A+PK +K+ Sbjct: 472 ASFLVAQVRKLNDSSS-RRPQLCDAGLKTWLRRMHADRDKAGDGLEATPKVAKI 524 >gi|56119110 family with sequence similarity 13, member A1 isoform a [Homo sapiens] Length = 1023 Score = 90.9 bits (224), Expect = 3e-18 Identities = 98/367 (26%), Positives = 157/367 (42%), Gaps = 49/367 (13%) Query: 179 EDMKKIRHLSLIELTAFF--DAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPG 236 EDMKKI + L E F FG+ L+ + E+ +NGI Sbjct: 19 EDMKKIVAVPLNEQKDFTYQKLFGVSLQ--ELERQGLTENGI------------------ 58 Query: 237 VKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREA 296 P V+ E + + GL EG+FR++G V+Q R + ++ + K +C A Sbjct: 59 ---PAVVWNIVEYLTQHGLTQEGLFRVNGNVKVVEQLRLKFESGVPVELGKDGDVC--SA 113 Query: 297 AVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALM 356 A +LK F RELP SL P FI L + G + VQ +L ++ LPD + + L Sbjct: 114 ASLLKLFLRELPDSLITSALQPRFIQLFQDGRN-DVQESSLRDLIKELPDTHYCLLKYLC 172 Query: 357 TFFNKVIANESKNRMSLWNISTVMAPNLFFSRSKHSDYEELLLANTAAHIIRLMLKYQKI 416 F KV + +NRM++ N++TV PN F +E L N I+ +L+ Sbjct: 173 QFLTKVAKHHVQNRMNVHNLATVFGPNCFHVPPGLEGMKEQDLCN---KIMAKILENYNT 229 Query: 417 LWKVPSFLITQVRRMNEATMLLKKQL--PSVRKLLRRKTLERETASPKTSKVLQKSPSAR 474 L++V +R N A +++ K++ + +L + LER+ P + KS S Sbjct: 230 LFEVEYTENDHLRCENLARLIIVKEVYYKNSLPILLTRGLERDMPKPPPKTKIPKSRS-- 287 Query: 475 RMSDVPEGVIRVHAPLLSKVSMAIQLNNQTKAKDILAKFQYENRILHWQRAALSFLNGKW 534 EG I+ H L ++S I + + Y L +A ++ K Sbjct: 288 ------EGSIQAHRVLQPELSDGI--------PQLSLRLSYRKACLEDMNSAEGAISAKL 333 Query: 535 VKKEREE 541 V +E+ Sbjct: 334 VPSSQED 340 >gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens] Length = 1271 Score = 90.5 bits (223), Expect = 4e-18 Identities = 74/270 (27%), Positives = 122/270 (45%), Gaps = 12/270 (4%) Query: 125 EELSFEVSYSEMVTEALKRNKLKKSEIKKEDYVLTKFNVQKTRFGLTEAGDLSAEDMKKI 184 EE E+ S+ + K++I KED T + K + L + + + Sbjct: 960 EEFEIELEGSQTLRILCYEKCYNKTKIPKEDGESTDRLMGKGQVQLDPQALQDRDWQRTV 1019 Query: 185 RHLSLIE--LTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVPLV 242 ++ IE L+ F++ LKR + K G+FGV + V+ +R K VP + Sbjct: 1020 IAMNGIEVKLSVKFNSREFSLKRMPSRK----QTGVFGVKIAVVTKRERSK-----VPYI 1070 Query: 243 LQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAAVMLKA 302 +++ E++E G+E GI+R+SG ++ + D +M A LK Sbjct: 1071 VRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDVNNKDVSVMMSEMDVNAIAGTLKL 1130 Query: 303 FFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFNKV 362 +FRELP LF E+ P F + V + L+L+ ++LP+AN L+ +V Sbjct: 1131 YFRELPEPLFTDEFYPNFAEGIALSDPVAKESCMLNLL-LSLPEANLLTFLFLLDHLKRV 1189 Query: 363 IANESKNRMSLWNISTVMAPNLFFSRSKHS 392 E+ N+MSL N++TV P L K S Sbjct: 1190 AEKEAVNKMSLHNLATVFGPTLLRPSEKES 1219 >gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens] Length = 1227 Score = 88.2 bits (217), Expect = 2e-17 Identities = 60/203 (29%), Positives = 98/203 (48%), Gaps = 10/203 (4%) Query: 190 IELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVPLVLQKFFEK 249 ++L+ F++ LKR + K G+FGV + V+ +R K VP ++++ E+ Sbjct: 983 VKLSVKFNSREFSLKRMPSRK----QTGVFGVKIAVVTKRERSK-----VPYIVRQCVEE 1033 Query: 250 VEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAAVMLKAFFRELPT 309 +E G+E GI+R+SG ++ + D +M A LK +FRELP Sbjct: 1034 IERRGMEEVGIYRVSGVATDIQALKAAFDVNNKDVSVMMSEMDVNAIAGTLKLYFRELPE 1093 Query: 310 SLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFNKVIANESKN 369 LF E+ P F + V + L+L+ ++LP+AN L+ +V E+ N Sbjct: 1094 PLFTDEFYPNFAEGIALSDPVAKESCMLNLL-LSLPEANLLTFLFLLDHLKRVAEKEAVN 1152 Query: 370 RMSLWNISTVMAPNLFFSRSKHS 392 +MSL N++TV P L K S Sbjct: 1153 KMSLHNLATVFGPTLLRPSEKES 1175 >gi|188497642 ARHGAP15 [Homo sapiens] Length = 475 Score = 84.0 bits (206), Expect = 3e-16 Identities = 54/181 (29%), Positives = 94/181 (51%), Gaps = 8/181 (4%) Query: 239 VPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYR--EELDAKFNADKFKWDKMCHREA 296 VP +++ E VE+ GL+ +GI+R+SG A +++ R + K N D +W+ + Sbjct: 294 VPWFVKQCIEAVEKRGLDVDGIYRVSGNLATIQKLRFIVNQEEKLNLDDSQWEDIHVVTG 353 Query: 297 AVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALM 356 A LK FFRELP LFP + F+ +++ + + +A+ +V LP NRD + L Sbjct: 354 A--LKMFFRELPEPLFPYSFFEQFVEAIKKQDN-NTRIEAVKSLVQKLPPPNRDTMKVLF 410 Query: 357 TFFNKVIANESKNRMSLWNISTVMAPNLFFSRSKHSDYE-ELLLANTAAHIIRLMLKYQK 415 K++A SKN MS ++ V P L + ++ + ++ N A + ++ +Y K Sbjct: 411 GHLTKIVAKASKNLMSTQSLGIVFGPTLLRAENETGNMAIHMVYQNQIAEL--MLSEYSK 468 Query: 416 I 416 I Sbjct: 469 I 469 >gi|229094128 active breakpoint cluster region-related protein isoform c [Homo sapiens] Length = 813 Score = 83.6 bits (205), Expect = 4e-16 Identities = 58/195 (29%), Positives = 93/195 (47%), Gaps = 10/195 (5%) Query: 190 IELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVPLVLQKFFEK 249 +E + F + + LKR ++K G+FGV ++V+ +R K VP ++++ E+ Sbjct: 574 VEFSMKFTSRDMSLKRTPSKK----QTGVFGVKISVVTKRERSK-----VPYIVRQCVEE 624 Query: 250 VEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAAVMLKAFFRELPT 309 VE+ G+E GI+R+SG ++ + DA M A LK +FRELP Sbjct: 625 VEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDMDINAIAGTLKLYFRELPE 684 Query: 310 SLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFNKVIANESKN 369 L PAF+ + + +HL+ +LPD N L+ +V E N Sbjct: 685 PLLTDRLYPAFMEGIALSDPAAKENCMMHLL-RSLPDPNLITFLFLLEHLKRVAEKEPIN 743 Query: 370 RMSLWNISTVMAPNL 384 +MSL N++TV P L Sbjct: 744 KMSLHNLATVFGPTL 758 >gi|33188433 deleted in liver cancer 1 isoform 1 [Homo sapiens] Length = 1528 Score = 83.6 bits (205), Expect = 4e-16 Identities = 61/219 (27%), Positives = 106/219 (48%), Gaps = 18/219 (8%) Query: 177 SAEDMKKIRHLSLIELTAFFDAFGIQLKRN---------KTEKVKG-RDNGIFGVPLTVL 226 S M ++ SL++LTA + + K K KV +D +FGVPLTV Sbjct: 1024 SVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVN 1083 Query: 227 LDGDRKKDPGVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKF 286 + + G +P +Q+ + L+ G+FR SG ++++ R+ + D Sbjct: 1084 V-----QRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAI--DCV 1136 Query: 287 KWDKMCHREAAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPD 346 ++ + A MLK +FR+LP L + F+ + + P + + QA+ +M LPD Sbjct: 1137 NYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQ-RLQAIKAAIMLLPD 1195 Query: 347 ANRDAAQALMTFFNKVIANESKNRMSLWNISTVMAPNLF 385 NR+ Q L+ F + V A +N+M+ N++ +AP+LF Sbjct: 1196 ENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLF 1234 Score = 41.2 bits (95), Expect = 0.003 Identities = 40/156 (25%), Positives = 65/156 (41%), Gaps = 20/156 (12%) Query: 52 SMPDDASLNSTTLSDASQDKEGSFAVPRSDSVAILETIPVLPVHSNGSPEPGQPVQNAI- 110 S P D TL D S+ +E S SV L + LP H+ S + P N++ Sbjct: 570 SHPKDGPSPGGTLMDLSERQEVS-------SVRSLSSTGSLPSHAPPSEDAATPRTNSVI 622 Query: 111 ----------SDDDFLEKNIPPEAEELSFEVSYSEMVTEALKRNKLKKSEIKKEDYVLTK 160 +DD F P E SF + E ++ R+ LK+ E K Sbjct: 623 SVCSSSNLAGNDDSFGSLPSPKELSSFSFSMKGHEKTAKSKTRSLLKRMESLKLKSSHHS 682 Query: 161 FNVQKTRFGLTEAGDLSAE--DMKKIRHLSLIELTA 194 + ++ GL +G + E D +K++ L+ +E++A Sbjct: 683 KHKAPSKLGLIISGPILQEGMDEEKLKQLNCVEISA 718 >gi|33188437 deleted in liver cancer 1 isoform 2 [Homo sapiens] Length = 1091 Score = 83.6 bits (205), Expect = 4e-16 Identities = 61/219 (27%), Positives = 106/219 (48%), Gaps = 18/219 (8%) Query: 177 SAEDMKKIRHLSLIELTAFFDAFGIQLKRN---------KTEKVKG-RDNGIFGVPLTVL 226 S M ++ SL++LTA + + K K KV +D +FGVPLTV Sbjct: 587 SVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVN 646 Query: 227 LDGDRKKDPGVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKF 286 + + G +P +Q+ + L+ G+FR SG ++++ R+ + D Sbjct: 647 V-----QRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAI--DCV 699 Query: 287 KWDKMCHREAAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPD 346 ++ + A MLK +FR+LP L + F+ + + P + + QA+ +M LPD Sbjct: 700 NYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQ-RLQAIKAAIMLLPD 758 Query: 347 ANRDAAQALMTFFNKVIANESKNRMSLWNISTVMAPNLF 385 NR+ Q L+ F + V A +N+M+ N++ +AP+LF Sbjct: 759 ENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLF 797 Score = 41.2 bits (95), Expect = 0.003 Identities = 40/156 (25%), Positives = 65/156 (41%), Gaps = 20/156 (12%) Query: 52 SMPDDASLNSTTLSDASQDKEGSFAVPRSDSVAILETIPVLPVHSNGSPEPGQPVQNAI- 110 S P D TL D S+ +E S SV L + LP H+ S + P N++ Sbjct: 133 SHPKDGPSPGGTLMDLSERQEVS-------SVRSLSSTGSLPSHAPPSEDAATPRTNSVI 185 Query: 111 ----------SDDDFLEKNIPPEAEELSFEVSYSEMVTEALKRNKLKKSEIKKEDYVLTK 160 +DD F P E SF + E ++ R+ LK+ E K Sbjct: 186 SVCSSSNLAGNDDSFGSLPSPKELSSFSFSMKGHEKTAKSKTRSLLKRMESLKLKSSHHS 245 Query: 161 FNVQKTRFGLTEAGDLSAE--DMKKIRHLSLIELTA 194 + ++ GL +G + E D +K++ L+ +E++A Sbjct: 246 KHKAPSKLGLIISGPILQEGMDEEKLKQLNCVEISA 281 >gi|38679957 active breakpoint cluster region-related protein isoform a [Homo sapiens] Length = 859 Score = 83.6 bits (205), Expect = 4e-16 Identities = 58/195 (29%), Positives = 93/195 (47%), Gaps = 10/195 (5%) Query: 190 IELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVPLVLQKFFEK 249 +E + F + + LKR ++K G+FGV ++V+ +R K VP ++++ E+ Sbjct: 620 VEFSMKFTSRDMSLKRTPSKK----QTGVFGVKISVVTKRERSK-----VPYIVRQCVEE 670 Query: 250 VEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAAVMLKAFFRELPT 309 VE+ G+E GI+R+SG ++ + DA M A LK +FRELP Sbjct: 671 VEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDMDINAIAGTLKLYFRELPE 730 Query: 310 SLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFNKVIANESKN 369 L PAF+ + + +HL+ +LPD N L+ +V E N Sbjct: 731 PLLTDRLYPAFMEGIALSDPAAKENCMMHLL-RSLPDPNLITFLFLLEHLKRVAEKEPIN 789 Query: 370 RMSLWNISTVMAPNL 384 +MSL N++TV P L Sbjct: 790 KMSLHNLATVFGPTL 804 >gi|38679954 active breakpoint cluster region-related protein isoform b [Homo sapiens] Length = 822 Score = 83.6 bits (205), Expect = 4e-16 Identities = 58/195 (29%), Positives = 93/195 (47%), Gaps = 10/195 (5%) Query: 190 IELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVPLVLQKFFEK 249 +E + F + + LKR ++K G+FGV ++V+ +R K VP ++++ E+ Sbjct: 583 VEFSMKFTSRDMSLKRTPSKK----QTGVFGVKISVVTKRERSK-----VPYIVRQCVEE 633 Query: 250 VEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAAVMLKAFFRELPT 309 VE+ G+E GI+R+SG ++ + DA M A LK +FRELP Sbjct: 634 VEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDMDINAIAGTLKLYFRELPE 693 Query: 310 SLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMTFFNKVIANESKN 369 L PAF+ + + +HL+ +LPD N L+ +V E N Sbjct: 694 PLLTDRLYPAFMEGIALSDPAAKENCMMHLL-RSLPDPNLITFLFLLEHLKRVAEKEPIN 752 Query: 370 RMSLWNISTVMAPNL 384 +MSL N++TV P L Sbjct: 753 KMSLHNLATVFGPTL 767 >gi|26986534 Rho GTPase activating protein 12 [Homo sapiens] Length = 846 Score = 80.1 bits (196), Expect = 5e-15 Identities = 51/148 (34%), Positives = 80/148 (54%), Gaps = 6/148 (4%) Query: 239 VPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREEL--DAKFNADKFKWDKMCHREA 296 VP ++ E VEE GL+ +GI+R+SG A +++ R + D K + + KW+ + Sbjct: 669 VPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKLRFAVNHDEKLDLNDSKWEDIHVITG 728 Query: 297 AVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALM 356 A LK FFRELP LF + F++ +++ P +V A+ ++ LP N+D Q L Sbjct: 729 A--LKMFFRELPEPLFTFNHFNDFVNAIKQEPRQRVA--AVKDLIRQLPKPNQDTMQILF 784 Query: 357 TFFNKVIANESKNRMSLWNISTVMAPNL 384 +VI N KNRM+ +I+ V P L Sbjct: 785 RHLRRVIENGEKNRMTYQSIAIVFGPTL 812 >gi|41281907 StAR-related lipid transfer (START) domain containing 13 isoform beta [Homo sapiens] Length = 1105 Score = 79.7 bits (195), Expect = 6e-15 Identities = 56/219 (25%), Positives = 105/219 (47%), Gaps = 18/219 (8%) Query: 177 SAEDMKKIRHLSLIELTAFFDAFGIQLKRNKTEKVKG----------RDNGIFGVPLTVL 226 +A + ++ SL+ LTA + + K T V +D +FGVPL V Sbjct: 601 TASQLSLLQRFSLLRLTAIMEKHSMSNKHGWTWSVPKFMKRMKVPDYKDKAVFGVPLIVH 660 Query: 227 LDGDRKKDPGVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKF 286 + + G +P +Q+ + + L+ G+FR SG +++ R+ ++ F + Sbjct: 661 V-----QRTGQPLPQSIQQALRYLRSNCLDQVGLFRKSGVKSRIHALRQ-MNENF-PENV 713 Query: 287 KWDKMCHREAAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPD 346 ++ + A M+K FFR+LP LF + F+ + + + + QA+ ++ L D Sbjct: 714 NYEDQSAYDVADMVKQFFRDLPEPLFTNKLSETFLHIYQYVSKEQ-RLQAVQAAILLLAD 772 Query: 347 ANRDAAQALMTFFNKVIANESKNRMSLWNISTVMAPNLF 385 NR+ Q L+ F N V+ +N+M+ N++ +AP+LF Sbjct: 773 ENREVLQTLLCFLNDVVNLVEENQMTPMNLAVCLAPSLF 811 >gi|16445031 StAR-related lipid transfer (START) domain containing 13 isoform gamma [Homo sapiens] Length = 995 Score = 79.7 bits (195), Expect = 6e-15 Identities = 56/219 (25%), Positives = 105/219 (47%), Gaps = 18/219 (8%) Query: 177 SAEDMKKIRHLSLIELTAFFDAFGIQLKRNKTEKVKG----------RDNGIFGVPLTVL 226 +A + ++ SL+ LTA + + K T V +D +FGVPL V Sbjct: 491 TASQLSLLQRFSLLRLTAIMEKHSMSNKHGWTWSVPKFMKRMKVPDYKDKAVFGVPLIVH 550 Query: 227 LDGDRKKDPGVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKF 286 + + G +P +Q+ + + L+ G+FR SG +++ R+ ++ F + Sbjct: 551 V-----QRTGQPLPQSIQQALRYLRSNCLDQVGLFRKSGVKSRIHALRQ-MNENF-PENV 603 Query: 287 KWDKMCHREAAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPD 346 ++ + A M+K FFR+LP LF + F+ + + + + QA+ ++ L D Sbjct: 604 NYEDQSAYDVADMVKQFFRDLPEPLFTNKLSETFLHIYQYVSKEQ-RLQAVQAAILLLAD 662 Query: 347 ANRDAAQALMTFFNKVIANESKNRMSLWNISTVMAPNLF 385 NR+ Q L+ F N V+ +N+M+ N++ +AP+LF Sbjct: 663 ENREVLQTLLCFLNDVVNLVEENQMTPMNLAVCLAPSLF 701 >gi|41281898 StAR-related lipid transfer (START) domain containing 13 isoform alpha [Homo sapiens] Length = 1113 Score = 79.7 bits (195), Expect = 6e-15 Identities = 56/219 (25%), Positives = 105/219 (47%), Gaps = 18/219 (8%) Query: 177 SAEDMKKIRHLSLIELTAFFDAFGIQLKRNKTEKVKG----------RDNGIFGVPLTVL 226 +A + ++ SL+ LTA + + K T V +D +FGVPL V Sbjct: 609 TASQLSLLQRFSLLRLTAIMEKHSMSNKHGWTWSVPKFMKRMKVPDYKDKAVFGVPLIVH 668 Query: 227 LDGDRKKDPGVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKF 286 + + G +P +Q+ + + L+ G+FR SG +++ R+ ++ F + Sbjct: 669 V-----QRTGQPLPQSIQQALRYLRSNCLDQVGLFRKSGVKSRIHALRQ-MNENF-PENV 721 Query: 287 KWDKMCHREAAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPD 346 ++ + A M+K FFR+LP LF + F+ + + + + QA+ ++ L D Sbjct: 722 NYEDQSAYDVADMVKQFFRDLPEPLFTNKLSETFLHIYQYVSKEQ-RLQAVQAAILLLAD 780 Query: 347 ANRDAAQALMTFFNKVIANESKNRMSLWNISTVMAPNLF 385 NR+ Q L+ F N V+ +N+M+ N++ +AP+LF Sbjct: 781 ENREVLQTLLCFLNDVVNLVEENQMTPMNLAVCLAPSLF 819 >gi|226693398 Rho GTPase activating protein 27 isoform b [Homo sapiens] Length = 521 Score = 79.0 bits (193), Expect = 1e-14 Identities = 50/169 (29%), Positives = 89/169 (52%), Gaps = 10/169 (5%) Query: 218 IFGVPLTVLLDGDRKKDPGVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVK--QYRE 275 +FG L L + +R + VP +Q+ VE GL+ +G++R+SG A ++ +Y+ Sbjct: 326 VFGCALAALCERERSR-----VPRFVQQCIRAVEARGLDIDGLYRISGNLATIQKLRYKV 380 Query: 276 ELDAKFNADKFKWDKMCHREAAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQ 335 + D + + D +W+ + A LK FFRELP LFP + FI+ ++ + + + Sbjct: 381 DHDERLDLDDGRWEDVHVITGA--LKLFFRELPEPLFPFSHFRQFIAAIKLQDQAR-RSR 437 Query: 336 ALHLMVMALPDANRDAAQALMTFFNKVIANESKNRMSLWNISTVMAPNL 384 + +V +LP N D + L +VI + +NRMS+ +++ V P L Sbjct: 438 CVRDLVRSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTL 486 >gi|40548322 Rho GTPase activating protein 27 isoform a [Homo sapiens] Length = 548 Score = 79.0 bits (193), Expect = 1e-14 Identities = 50/169 (29%), Positives = 89/169 (52%), Gaps = 10/169 (5%) Query: 218 IFGVPLTVLLDGDRKKDPGVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVK--QYRE 275 +FG L L + +R + VP +Q+ VE GL+ +G++R+SG A ++ +Y+ Sbjct: 353 VFGCALAALCERERSR-----VPRFVQQCIRAVEARGLDIDGLYRISGNLATIQKLRYKV 407 Query: 276 ELDAKFNADKFKWDKMCHREAAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQ 335 + D + + D +W+ + A LK FFRELP LFP + FI+ ++ + + + Sbjct: 408 DHDERLDLDDGRWEDVHVITGA--LKLFFRELPEPLFPFSHFRQFIAAIKLQDQAR-RSR 464 Query: 336 ALHLMVMALPDANRDAAQALMTFFNKVIANESKNRMSLWNISTVMAPNL 384 + +V +LP N D + L +VI + +NRMS+ +++ V P L Sbjct: 465 CVRDLVRSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTL 513 >gi|7382480 Rho GTPase activating protein 6 isoform 4 [Homo sapiens] Length = 771 Score = 76.3 bits (186), Expect = 7e-14 Identities = 69/247 (27%), Positives = 114/247 (46%), Gaps = 28/247 (11%) Query: 238 KVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAA 297 +VP ++ + +E+ GL++ GIFR+ +V+Q REE D D ++ + A Sbjct: 206 QVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDR--GIDVSLEEEHSVHDVA 263 Query: 298 VMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMT 357 +LK F R++P L E AFI+ + P + Q L L++ LP N D L+ Sbjct: 264 ALLKEFLRDMPDPLLTRELYTAFINTLLLEP--EEQLGTLQLLIYLLPPCNCDTLHRLLQ 321 Query: 358 FFNKVIA----NESK-------NRMSLWNISTVMAPNLFFSRSKHSDYEELLLANTAAH- 405 F + V N SK N+M+ N++T+ PNL + K SD E + ++ A Sbjct: 322 FLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNL-LHKQKSSDKEFSVQSSARAEE 380 Query: 406 ------IIRLMLKYQKILWKVPSFLITQVRRMNEATMLLKKQLPSVRKLLRRKTLERETA 459 +++ M++ + L+ VP L +V LL+ V LLRRK + + Sbjct: 381 STAIIAVVQKMIENYEALFMVPPDLQNEV-----LISLLETDPDVVDYLLRRKASQSSSP 435 Query: 460 SPKTSKV 466 S+V Sbjct: 436 DMLQSEV 442 >gi|95091988 Rho GTPase activating protein 6 isoform 3 [Homo sapiens] Length = 765 Score = 76.3 bits (186), Expect = 7e-14 Identities = 69/247 (27%), Positives = 114/247 (46%), Gaps = 28/247 (11%) Query: 238 KVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAA 297 +VP ++ + +E+ GL++ GIFR+ +V+Q REE D D ++ + A Sbjct: 409 QVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDR--GIDVSLEEEHSVHDVA 466 Query: 298 VMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMT 357 +LK F R++P L E AFI+ + P + Q L L++ LP N D L+ Sbjct: 467 ALLKEFLRDMPDPLLTRELYTAFINTLLLEP--EEQLGTLQLLIYLLPPCNCDTLHRLLQ 524 Query: 358 FFNKVIA----NESK-------NRMSLWNISTVMAPNLFFSRSKHSDYEELLLANTAAH- 405 F + V N SK N+M+ N++T+ PNL + K SD E + ++ A Sbjct: 525 FLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNL-LHKQKSSDKEFSVQSSARAEE 583 Query: 406 ------IIRLMLKYQKILWKVPSFLITQVRRMNEATMLLKKQLPSVRKLLRRKTLERETA 459 +++ M++ + L+ VP L +V LL+ V LLRRK + + Sbjct: 584 STAIIAVVQKMIENYEALFMVPPDLQNEV-----LISLLETDPDVVDYLLRRKASQSSSP 638 Query: 460 SPKTSKV 466 S+V Sbjct: 639 DMLQSEV 645 >gi|95091875 Rho GTPase activating protein 6 isoform 1 [Homo sapiens] Length = 974 Score = 76.3 bits (186), Expect = 7e-14 Identities = 69/247 (27%), Positives = 114/247 (46%), Gaps = 28/247 (11%) Query: 238 KVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAA 297 +VP ++ + +E+ GL++ GIFR+ +V+Q REE D D ++ + A Sbjct: 409 QVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDR--GIDVSLEEEHSVHDVA 466 Query: 298 VMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQALMT 357 +LK F R++P L E AFI+ + P + Q L L++ LP N D L+ Sbjct: 467 ALLKEFLRDMPDPLLTRELYTAFINTLLLEP--EEQLGTLQLLIYLLPPCNCDTLHRLLQ 524 Query: 358 FFNKVIA----NESK-------NRMSLWNISTVMAPNLFFSRSKHSDYEELLLANTAAH- 405 F + V N SK N+M+ N++T+ PNL + K SD E + ++ A Sbjct: 525 FLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNL-LHKQKSSDKEFSVQSSARAEE 583 Query: 406 ------IIRLMLKYQKILWKVPSFLITQVRRMNEATMLLKKQLPSVRKLLRRKTLERETA 459 +++ M++ + L+ VP L +V LL+ V LLRRK + + Sbjct: 584 STAIIAVVQKMIENYEALFMVPPDLQNEV-----LISLLETDPDVVDYLLRRKASQSSSP 638 Query: 460 SPKTSKV 466 S+V Sbjct: 639 DMLQSEV 645 >gi|5803145 ralA binding protein 1 [Homo sapiens] Length = 655 Score = 75.9 bits (185), Expect = 9e-14 Identities = 48/170 (28%), Positives = 89/170 (52%), Gaps = 5/170 (2%) Query: 218 IFGVPLTVLLDGDRKKDPGVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREEL 277 IFG+PL ++ D G+++P V ++ + VE+ G++ EGI+R+SG +KV + + Sbjct: 189 IFGIPLADAVERTMMYD-GIRLPAVFRECIDYVEKYGMKCEGIYRVSGIKSKVDELKAAY 247 Query: 278 DAKFNADKFKWDKMCHREAAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQAL 337 D + + + ++ A +LK + R+LP +L E +P F R + + Q Sbjct: 248 DREESTNLEDYEP---NTVASLLKQYLRDLPENLLTKELMPRFEEACGRTTETE-KVQEF 303 Query: 338 HLMVMALPDANRDAAQALMTFFNKVIANESKNRMSLWNISTVMAPNLFFS 387 ++ LP+ N L+ + VIA E + +M++ NIS V++P + S Sbjct: 304 QRLLKELPECNYLLISWLIVHMDHVIAKELETKMNIQNISIVLSPTVQIS 353 >gi|215820652 StAR-related lipid transfer (START) domain containing 8 isoform b [Homo sapiens] Length = 1023 Score = 75.9 bits (185), Expect = 9e-14 Identities = 54/210 (25%), Positives = 103/210 (49%), Gaps = 23/210 (10%) Query: 188 SLIELTAFFDAFGIQ------------LKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDP 235 SL+ LTAF + + + ++RNKT +G+ +FGVP + + + Sbjct: 529 SLLRLTAFMEKYTVPHKQGWVWSMPKFMRRNKTPDYRGQH--VFGVPPLIHV-----QRT 581 Query: 236 GVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHRE 295 G +P +Q+ + L+ GIFR SG ++++ R+ + + D ++ + Sbjct: 582 GQPLPQSIQQAMRYLRSQCLDQVGIFRKSGVKSRIQNLRQMNET--SPDNVCYEGQSAYD 639 Query: 296 AAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQAL 355 A +LK +FR+LP +F + F+ + + P + A + LPD NR+ Q L Sbjct: 640 VADLLKQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQ-WLAAAQAATLLLPDENREVLQTL 698 Query: 356 MTFFNKVIANESKNRMSLWNISTVMAPNLF 385 + F + IA+ +N+M+ N++ +AP++F Sbjct: 699 LYFLSD-IASAEENQMTAGNLAVCLAPSIF 727 >gi|215820650 StAR-related lipid transfer (START) domain containing 8 isoform a [Homo sapiens] Length = 1103 Score = 75.9 bits (185), Expect = 9e-14 Identities = 54/210 (25%), Positives = 103/210 (49%), Gaps = 23/210 (10%) Query: 188 SLIELTAFFDAFGIQ------------LKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDP 235 SL+ LTAF + + + ++RNKT +G+ +FGVP + + + Sbjct: 609 SLLRLTAFMEKYTVPHKQGWVWSMPKFMRRNKTPDYRGQH--VFGVPPLIHV-----QRT 661 Query: 236 GVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHRE 295 G +P +Q+ + L+ GIFR SG ++++ R+ + + D ++ + Sbjct: 662 GQPLPQSIQQAMRYLRSQCLDQVGIFRKSGVKSRIQNLRQMNET--SPDNVCYEGQSAYD 719 Query: 296 AAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQAL 355 A +LK +FR+LP +F + F+ + + P + A + LPD NR+ Q L Sbjct: 720 VADLLKQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQ-WLAAAQAATLLLPDENREVLQTL 778 Query: 356 MTFFNKVIANESKNRMSLWNISTVMAPNLF 385 + F + IA+ +N+M+ N++ +AP++F Sbjct: 779 LYFLSD-IASAEENQMTAGNLAVCLAPSIF 807 >gi|31543659 StAR-related lipid transfer (START) domain containing 8 isoform b [Homo sapiens] Length = 1023 Score = 75.9 bits (185), Expect = 9e-14 Identities = 54/210 (25%), Positives = 103/210 (49%), Gaps = 23/210 (10%) Query: 188 SLIELTAFFDAFGIQ------------LKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDP 235 SL+ LTAF + + + ++RNKT +G+ +FGVP + + + Sbjct: 529 SLLRLTAFMEKYTVPHKQGWVWSMPKFMRRNKTPDYRGQH--VFGVPPLIHV-----QRT 581 Query: 236 GVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHRE 295 G +P +Q+ + L+ GIFR SG ++++ R+ + + D ++ + Sbjct: 582 GQPLPQSIQQAMRYLRSQCLDQVGIFRKSGVKSRIQNLRQMNET--SPDNVCYEGQSAYD 639 Query: 296 AAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQAL 355 A +LK +FR+LP +F + F+ + + P + A + LPD NR+ Q L Sbjct: 640 VADLLKQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQ-WLAAAQAATLLLPDENREVLQTL 698 Query: 356 MTFFNKVIANESKNRMSLWNISTVMAPNLF 385 + F + IA+ +N+M+ N++ +AP++F Sbjct: 699 LYFLSD-IASAEENQMTAGNLAVCLAPSIF 727 >gi|156119615 myosin IXA [Homo sapiens] Length = 2548 Score = 75.1 bits (183), Expect = 2e-13 Identities = 83/328 (25%), Positives = 139/328 (42%), Gaps = 40/328 (12%) Query: 219 FGVPLTVLLDGDRKKDPGVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELD 278 FGV L+ L DR VPLV++K +E GL +EGI+R SG T K+K+ R+ LD Sbjct: 2061 FGVELSRLTSEDRT------VPLVVEKLINYIEMHGLYTEGIYRKSGSTNKIKELRQGLD 2114 Query: 279 AKFNADKFKWDKMCHREAAVMLKAFFRELPTSLFPVEYIPAFI---SLMERGPHVKVQFQ 335 +A+ D A + K + R+LP L E F+ L ER K + Sbjct: 2115 T--DAESVNLDDYNIHVIASVFKQWLRDLPNPLMTFELYEEFLRAMGLQER----KETIR 2168 Query: 336 ALHLMVMALPDANRDAAQALMTFFNKVIANESKNRMSLWNISTVMAPNLFFSRSKHSDYE 395 ++ ++ L + + + L+ ++ E NRMS ++ V AP + + Sbjct: 2169 GVYSVIDQLSRTHLNTLERLIFHLVRIALQEDTNRMSANALAIVFAPCILRCPDTTDPLQ 2228 Query: 396 ELLLANTAAHIIRLMLKYQKILWKVPSFLITQVRRMNEATMLLKKQLPSVRKLLRRKTLE 455 + + + L++ Q +K + + + A K +L +R+ + + + Sbjct: 2229 SVQDISKTTTCVELIVVEQMNKYKA---RLKDISSLEFAENKAKTRLSLIRRSMGKGRIR 2285 Query: 456 RETASPKTSKVLQKSPSARRMSDVPEGVIRVHAPLLSKVSMAIQLNNQTKAKDILAKFQY 515 R +S V+ + PS +SDV E L S+ +M + Q + A Q Sbjct: 2286 RGNYPGPSSPVVVRLPS---VSDVSE------ETLTSEAAMETDITEQQQ-----AAMQQ 2331 Query: 516 ENRILHWQRAALSFLNGKWVKKEREEST 543 E R+L Q L +KE+EE T Sbjct: 2332 EERVLTEQIENL--------QKEKEELT 2351 >gi|150417981 glucocorticoid receptor DNA binding factor 1 [Homo sapiens] Length = 1499 Score = 73.2 bits (178), Expect = 6e-13 Identities = 58/201 (28%), Positives = 95/201 (47%), Gaps = 16/201 (7%) Query: 215 DNGIFGVPLTVLLDGDRKKDPGVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYR 274 ++ FGVPLT ++ P +P+ +++ E +E +GL +EGI+R+SG ++++ + Sbjct: 1243 ESNYFGVPLTTVVT------PEKPIPIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQ 1296 Query: 275 EELDAKFNADKFKWDKMCHREAAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQF 334 + D N D + D + A M K+FF ELP L P I L+E + + Sbjct: 1297 RQFDQDHNLDLAEKDFTVNTVAGAM-KSFFSELPDPLVPYN---MQIDLVE-AHKINDRE 1351 Query: 335 QALHLMVMAL---PDANRDAAQALMTFFNKVIANESKNRMSLWNISTVMAPNLFFSRSKH 391 Q LH + L P N + + +++ NKV N N M+ N+S P L R Sbjct: 1352 QKLHALKEVLKKFPKENHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTLM--RPDF 1409 Query: 392 SDYEELLLANTAAHIIRLMLK 412 S + L T II L ++ Sbjct: 1410 STMDALTATRTYQTIIELFIQ 1430 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.132 0.372 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 19,722,180 Number of Sequences: 37866 Number of extensions: 850713 Number of successful extensions: 3177 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 85 Number of HSP's successfully gapped in prelim test: 48 Number of HSP's that attempted gapping in prelim test: 2905 Number of HSP's gapped (non-prelim): 180 length of query: 563 length of database: 18,247,518 effective HSP length: 107 effective length of query: 456 effective length of database: 14,195,856 effective search space: 6473310336 effective search space used: 6473310336 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.