Guide to the Human Genome
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Search of human proteins with 5902724

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens]
         (492 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens]         949   0.0  
gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo ...   682   0.0  
gi|56549653 neuro-oncological ventral antigen 1 isoform 1 [Homo ...   669   0.0  
gi|6031189 neuro-oncological ventral antigen 1 isoform 3 [Homo s...   221   1e-57
gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens]       94   4e-19
gi|14670373 poly(rC) binding protein 4 isoform c [Homo sapiens]        80   3e-15
gi|14670369 poly(rC) binding protein 4 isoform c [Homo sapiens]        80   3e-15
gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens]       79   9e-15
gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens]        78   2e-14
gi|56118219 insulin-like growth factor 2 mRNA binding protein 2 ...    77   3e-14
gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens]       77   4e-14
gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens]       77   4e-14
gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens]       77   4e-14
gi|222352151 poly(rC) binding protein 1 [Homo sapiens]                 75   1e-13
gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens]       75   2e-13
gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens]       75   2e-13
gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens]        75   2e-13
gi|17402900 far upstream element-binding protein [Homo sapiens]        74   2e-13
gi|122937319 even-skipped homeobox 2 [Homo sapiens]                    71   2e-12
gi|145312259 tudor and KH domain containing isoform a [Homo sapi...    71   2e-12
gi|145312270 tudor and KH domain containing isoform a [Homo sapi...    71   2e-12
gi|145312256 tudor and KH domain containing isoform a [Homo sapi...    71   2e-12
gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a ...    70   3e-12
gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b ...    70   3e-12
gi|14165437 heterogeneous nuclear ribonucleoprotein K isoform a ...    70   3e-12
gi|100816392 far upstream element (FUSE) binding protein 3 [Homo...    69   7e-12
gi|64085377 insulin-like growth factor 2 mRNA binding protein 2 ...    69   1e-11
gi|154355000 KH-type splicing regulatory protein [Homo sapiens]        66   6e-11
gi|30795212 insulin-like growth factor 2 mRNA binding protein 3 ...    62   2e-09
gi|73427806 v-maf musculoaponeurotic fibrosarcoma oncogene homol...    61   2e-09

>gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens]
          Length = 492

 Score =  949 bits (2454), Expect = 0.0
 Identities = 492/492 (100%), Positives = 492/492 (100%)

Query: 1   MEPEAPDSRKRPLETPPEVVCTKRSNTGEEGEYFLKVLIPSYAAGSIIGKGGQTIVQLQK 60
           MEPEAPDSRKRPLETPPEVVCTKRSNTGEEGEYFLKVLIPSYAAGSIIGKGGQTIVQLQK
Sbjct: 1   MEPEAPDSRKRPLETPPEVVCTKRSNTGEEGEYFLKVLIPSYAAGSIIGKGGQTIVQLQK 60

Query: 61  ETGATIKLSKSKDFYPGTTERVCLVQGTAEALNAVHSFIAEKVREIPQAMTKPEVVNILQ 120
           ETGATIKLSKSKDFYPGTTERVCLVQGTAEALNAVHSFIAEKVREIPQAMTKPEVVNILQ
Sbjct: 61  ETGATIKLSKSKDFYPGTTERVCLVQGTAEALNAVHSFIAEKVREIPQAMTKPEVVNILQ 120

Query: 121 PQTTMNPDRAKQAKLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVV 180
           PQTTMNPDRAKQAKLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVV
Sbjct: 121 PQTTMNPDRAKQAKLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVV 180

Query: 181 TVSGEPEQVHKAVSAIVQKVQEDPQSSSCLNISYANVAGPVANSNPTGSPYASPADVLPA 240
           TVSGEPEQVHKAVSAIVQKVQEDPQSSSCLNISYANVAGPVANSNPTGSPYASPADVLPA
Sbjct: 181 TVSGEPEQVHKAVSAIVQKVQEDPQSSSCLNISYANVAGPVANSNPTGSPYASPADVLPA 240

Query: 241 AAAASAAAASGLLGPAGLAGVGAFPAALPAFSGTDLLAISTALNTLASYGYNTNSLGLGL 300
           AAAASAAAASGLLGPAGLAGVGAFPAALPAFSGTDLLAISTALNTLASYGYNTNSLGLGL
Sbjct: 241 AAAASAAAASGLLGPAGLAGVGAFPAALPAFSGTDLLAISTALNTLASYGYNTNSLGLGL 300

Query: 301 NSAAASGVLAAVAAGANPAAAAAANLLASYAGEAGAGPAGGAAPPPPPPPGALGSFALAA 360
           NSAAASGVLAAVAAGANPAAAAAANLLASYAGEAGAGPAGGAAPPPPPPPGALGSFALAA
Sbjct: 301 NSAAASGVLAAVAAGANPAAAAAANLLASYAGEAGAGPAGGAAPPPPPPPGALGSFALAA 360

Query: 361 AANGYLGAGAGGGAGGGGGPLVAAAAAAGAAGGFLTAEKLAAESAKELVEIAVPENLVGA 420
           AANGYLGAGAGGGAGGGGGPLVAAAAAAGAAGGFLTAEKLAAESAKELVEIAVPENLVGA
Sbjct: 361 AANGYLGAGAGGGAGGGGGPLVAAAAAAGAAGGFLTAEKLAAESAKELVEIAVPENLVGA 420

Query: 421 ILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQAAQYLISQRVTYE 480
           ILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQAAQYLISQRVTYE
Sbjct: 421 ILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQAAQYLISQRVTYE 480

Query: 481 QGVRASNPQKVG 492
           QGVRASNPQKVG
Sbjct: 481 QGVRASNPQKVG 492


>gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo
           sapiens]
          Length = 483

 Score =  682 bits (1761), Expect = 0.0
 Identities = 370/492 (75%), Positives = 409/492 (83%), Gaps = 32/492 (6%)

Query: 4   EAPDSRKRPLETPPEVVCTKRSNTGEEGEYFLKVLIPSYAAGSIIGKGGQTIVQLQKETG 63
           + PDSRKRPLE PPE   TKR+NTGE+G+YFLKVLIPSYAAGSIIGKGGQTIVQLQKETG
Sbjct: 21  DPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETG 80

Query: 64  ATIKLSKSKDFYPGTTERVCLVQGTAEALNAVHSFIAEKVREIPQAMTKPEVVNILQPQT 123
           ATIKLSKSKDFYPGTTERVCL+QGT EALNAVH FIAEK+RE+PQ + K E V+ILQPQT
Sbjct: 81  ATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQT 140

Query: 124 TMNPDRAKQAKLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVS 183
           T+NPDR KQ K+IVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKP+GINLQERVVTVS
Sbjct: 141 TVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVS 200

Query: 184 GEPEQVHKAVSAIVQKVQEDPQSSSCLNISYANVAGPVANSNPTGSPYASPADVLPAAAA 243
           GEPEQ  KAV  I+QK+QEDPQS SCLNISYANV GPVANSNPTGSPYA+ A+VLP    
Sbjct: 201 GEPEQNRKAVELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLP---- 256

Query: 244 ASAAAASGLLGPAGLAGVGAFPAALPAFSGTDLLAISTALNTLASYGYNTNSLGLGLNSA 303
            +AAAA+GLLG A LAGV AFPA L  F+G DL+AI++ALNTLASYGYN N+LGLGL+ A
Sbjct: 257 -TAAAAAGLLGHANLAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQA 315

Query: 304 AASGVLAAVAAGANPAAAAAANLLASYAGEAGA--GPAGGAAPPPPPPPGALGSFALA-A 360
           AA+G LAA AA ANP AAAAANLLA+YA EA A    AGG A        ALGS A A A
Sbjct: 316 AATGALAAAAASANP-AAAAANLLATYASEASASGSTAGGTA-----GTFALGSLAAATA 369

Query: 361 AANGYLGAGAGGGAGGGGGPLVAAAAAAGAAGGFLTAEKLAAESAKELVEIAVPENLVGA 420
           A NGY GA +         PL A+A         L  EK + + +K++VEIAVPENLVGA
Sbjct: 370 ATNGYFGAAS---------PLAASA--------ILGTEK-STDGSKDVVEIAVPENLVGA 411

Query: 421 ILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQAAQYLISQRVTYE 480
           ILGKGGKTLVEYQELTGARIQISKKGEF+PGTRNR+VTITG+PAATQAAQYLI+QR+TYE
Sbjct: 412 ILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQYLITQRITYE 471

Query: 481 QGVRASNPQKVG 492
           QGVRA+NPQKVG
Sbjct: 472 QGVRAANPQKVG 483


>gi|56549653 neuro-oncological ventral antigen 1 isoform 1 [Homo
           sapiens]
          Length = 507

 Score =  669 bits (1726), Expect = 0.0
 Identities = 370/516 (71%), Positives = 409/516 (79%), Gaps = 56/516 (10%)

Query: 4   EAPDSRKRPLETPPEVVCTKRSNTGEEGEYFLKVLIPSYAAGSIIGKGGQTIVQLQKETG 63
           + PDSRKRPLE PPE   TKR+NTGE+G+YFLKVLIPSYAAGSIIGKGGQTIVQLQKETG
Sbjct: 21  DPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETG 80

Query: 64  ATIKLSKSKDFYPGTTERVCLVQGTAEALNAVHSFIAEKVREIPQAMTKPEVVNILQPQT 123
           ATIKLSKSKDFYPGTTERVCL+QGT EALNAVH FIAEK+RE+PQ + K E V+ILQPQT
Sbjct: 81  ATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQT 140

Query: 124 TMNPD------------------------RAKQAKLIVPNSTAGLIIGKGGATVKAVMEQ 159
           T+NPD                        RA Q K+IVPNSTAGLIIGKGGATVKAVMEQ
Sbjct: 141 TVNPDRIKQTLPSSPTTTKSSPSDPMTTSRANQVKIIVPNSTAGLIIGKGGATVKAVMEQ 200

Query: 160 SGAWVQLSQKPEGINLQERVVTVSGEPEQVHKAVSAIVQKVQEDPQSSSCLNISYANVAG 219
           SGAWVQLSQKP+GINLQERVVTVSGEPEQ  KAV  I+QK+QEDPQS SCLNISYANV G
Sbjct: 201 SGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSGSCLNISYANVTG 260

Query: 220 PVANSNPTGSPYASPADVLPAAAAASAAAASGLLGPAGLAGVGAFPAALPAFSGTDLLAI 279
           PVANSNPTGSPYA+ A+VLP     +AAAA+GLLG A LAGV AFPA L  F+G DL+AI
Sbjct: 261 PVANSNPTGSPYANTAEVLP-----TAAAAAGLLGHANLAGVAAFPAVLSGFTGNDLVAI 315

Query: 280 STALNTLASYGYNTNSLGLGLNSAAASGVLAAVAAGANPAAAAAANLLASYAGEAGA--G 337
           ++ALNTLASYGYN N+LGLGL+ AAA+G LAA AA ANP AAAAANLLA+YA EA A   
Sbjct: 316 TSALNTLASYGYNLNTLGLGLSQAAATGALAAAAASANP-AAAAANLLATYASEASASGS 374

Query: 338 PAGGAAPPPPPPPGALGSFALA-AAANGYLGAGAGGGAGGGGGPLVAAAAAAGAAGGFLT 396
            AGG A        ALGS A A AA NGY GA +         PL A+A         L 
Sbjct: 375 TAGGTA-----GTFALGSLAAATAATNGYFGAAS---------PLAASA--------ILG 412

Query: 397 AEKLAAESAKELVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRR 456
            EK + + +K++VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEF+PGTRNR+
Sbjct: 413 TEK-STDGSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRK 471

Query: 457 VTITGSPAATQAAQYLISQRVTYEQGVRASNPQKVG 492
           VTITG+PAATQAAQYLI+QR+TYEQGVRA+NPQKVG
Sbjct: 472 VTITGTPAATQAAQYLITQRITYEQGVRAANPQKVG 507


>gi|6031189 neuro-oncological ventral antigen 1 isoform 3 [Homo
           sapiens]
          Length = 181

 Score =  221 bits (563), Expect = 1e-57
 Identities = 109/138 (78%), Positives = 120/138 (86%)

Query: 4   EAPDSRKRPLETPPEVVCTKRSNTGEEGEYFLKVLIPSYAAGSIIGKGGQTIVQLQKETG 63
           + PDSRKRPLE PPE   TKR+NTGE+G+YFLKVLIPSYAAGSIIGKGGQTIVQLQKETG
Sbjct: 21  DPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETG 80

Query: 64  ATIKLSKSKDFYPGTTERVCLVQGTAEALNAVHSFIAEKVREIPQAMTKPEVVNILQPQT 123
           ATIKLSKSKDFYPGTTERVCL+QGT EALNAVH FIAEK+RE+PQ + K E V+ILQPQT
Sbjct: 81  ATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQT 140

Query: 124 TMNPDRAKQAKLIVPNST 141
           T+NPDR KQ     P +T
Sbjct: 141 TVNPDRIKQTLPSSPTTT 158



 Score = 59.7 bits (143), Expect = 6e-09
 Identities = 30/90 (33%), Positives = 51/90 (56%), Gaps = 1/90 (1%)

Query: 403 ESAKELVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGS 462
           E  +  +++ +P    G+I+GKGG+T+V+ Q+ TGA I++SK  +F PGT  R   I G+
Sbjct: 46  EDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGT 105

Query: 463 PAATQAAQYLISQRV-TYEQGVRASNPQKV 491
             A  A    I++++    Q V  + P  +
Sbjct: 106 VEALNAVHGFIAEKIREMPQNVAKTEPVSI 135



 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 27/86 (31%), Positives = 48/86 (55%), Gaps = 1/86 (1%)

Query: 122 QTTMNPDRAKQAKLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGI-NLQERVV 180
           +T    D     K+++P+  AG IIGKGG T+  + +++GA ++LS+  +      ERV 
Sbjct: 41  RTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVC 100

Query: 181 TVSGEPEQVHKAVSAIVQKVQEDPQS 206
            + G  E ++     I +K++E PQ+
Sbjct: 101 LIQGTVEALNAVHGFIAEKIREMPQN 126


>gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens]
          Length = 371

 Score = 93.6 bits (231), Expect = 4e-19
 Identities = 95/348 (27%), Positives = 150/348 (43%), Gaps = 33/348 (9%)

Query: 134 KLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKAV 193
           +L++     G IIGK G TVK + E+SGA + +S+     N  ER+VT++G  + + KA 
Sbjct: 49  RLLMHGKEVGSIIGKKGETVKKMREESGARINISEG----NCPERIVTITGPTDAIFKAF 104

Query: 194 SAIVQKVQEDPQSSSCLNISYANVAGPVANSNPTGSPYASPADVLPAAAAASAAAASGLL 253
           + I  K +ED             +   ++NS  T  P  +   V+PA+   S     G  
Sbjct: 105 AMIAYKFEED-------------IINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGG-- 149

Query: 254 GPAGLAGVGAFPAALPAFSGTDLLAISTALNTLASYGYNTNSLGLGLNSAAASGVLAAVA 313
             + +  +     A    +G D+L  ST      S    T    +         +L +  
Sbjct: 150 --SKIKEIRESTGAQVQVAG-DMLPNSTERAVTIS---GTPDAIIQCVKQICVVMLESPP 203

Query: 314 AGAN-PAAAAAANLLASYAGEAGAGPAGGAAPPPPPPPGALGSFALAAAANGYLGAGAGG 372
            GA  P     A+    +AG       G  A P P     L   A+       LG     
Sbjct: 204 KGATIPYRPKPASTPVIFAGGQAYTIQGQYAIPHPDQLTKLHQLAMQQTPFPPLGQ-TNP 262

Query: 373 GAGGGGGPLVAAAAAAGAAGGFLTAEKLAAESAKELVEIAVPENLVGAILGKGGKTLVEY 432
              G   PL ++  A    G    +  L A       E+ +P +L+G I+G+ G  + E 
Sbjct: 263 AFPGEKLPLHSSEEAQNLMG---QSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEI 319

Query: 433 QELTGARIQISKKGEFLPGTRNRRVTITGSPAATQAAQYLISQRVTYE 480
           ++++GA+I+I+   E   G+  R++TITG+PA    AQYLI+ R+T E
Sbjct: 320 RQMSGAQIKIANATE---GSSERQITITGTPANISLAQYLINARLTSE 364



 Score = 81.6 bits (200), Expect = 1e-15
 Identities = 58/193 (30%), Positives = 98/193 (50%), Gaps = 23/193 (11%)

Query: 22  TKRSNTGEEGEYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTER 81
           +K S  G      +++L+     GSIIGK G+T+ ++++E+GA I +S+         ER
Sbjct: 35  SKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGN-----CPER 89

Query: 82  VCLVQGTAEALNAVHSFIAEKVREIPQAMTKPEVVNILQ--PQTTMNPDRAKQAKLIVPN 139
           +  + G  +A+    + IA K  E        +++N +   P T+  P      +L+VP 
Sbjct: 90  IVTITGPTDAIFKAFAMIAYKFEE--------DIINSMSNSPATSKPP---VTLRLVVPA 138

Query: 140 STAGLIIGKGGATVKAVMEQSGAWVQLS--QKPEGINLQERVVTVSGEPEQVHKAVSAIV 197
           S  G +IGKGG+ +K + E +GA VQ++    P   N  ER VT+SG P+ + + V  I 
Sbjct: 139 SQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLP---NSTERAVTISGTPDAIIQCVKQIC 195

Query: 198 QKVQEDPQSSSCL 210
             + E P   + +
Sbjct: 196 VVMLESPPKGATI 208



 Score = 52.4 bits (124), Expect = 9e-07
 Identities = 48/226 (21%), Positives = 90/226 (39%), Gaps = 72/226 (31%)

Query: 35  LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTE-------------- 80
           L++++P+   GS+IGKGG  I ++++ TGA ++++   D  P +TE              
Sbjct: 132 LRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAG--DMLPNSTERAVTISGTPDAIIQ 189

Query: 81  ---RVCLVQ-------------------------GTA------------EALNAVHSFIA 100
              ++C+V                          G A            + L  +H    
Sbjct: 190 CVKQICVVMLESPPKGATIPYRPKPASTPVIFAGGQAYTIQGQYAIPHPDQLTKLHQLAM 249

Query: 101 EKVREIPQAMTKP-------------EVVNILQPQTTMNPDR-AKQAKLIVPNSTAGLII 146
           ++    P   T P             E  N++   + ++    A   +L +PN   G II
Sbjct: 250 QQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCII 309

Query: 147 GKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKA 192
           G+ G  +  + + SGA ++++   EG +  ER +T++G P  +  A
Sbjct: 310 GRQGTKINEIRQMSGAQIKIANATEGSS--ERQITITGTPANISLA 353


>gi|14670373 poly(rC) binding protein 4 isoform c [Homo sapiens]
          Length = 403

 Score = 80.5 bits (197), Expect = 3e-15
 Identities = 91/347 (26%), Positives = 140/347 (40%), Gaps = 67/347 (19%)

Query: 134 KLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKAV 193
           ++++     G IIGK G TVK + EQS A + +S+     +  ER+ T++G    V  AV
Sbjct: 21  RMLMHGKEVGSIIGKKGETVKRIREQSSARITISEG----SCPERITTITGSTAAVFHAV 76

Query: 194 SAIVQKVQEDPQSSSCLNISYANVAGPVANSNPTGSPYASPADVLPAAAAASAAAASGLL 253
           S I  K+ ED             +    AN      P  +   V+PA+   S      L+
Sbjct: 77  SMIAFKLDED-------------LCAAPANGGNVSRPPVTLRLVIPASQCGS------LI 117

Query: 254 GPAG--LAGVGAFPAALPAFSGTDLLAISTALNTLASYGYNTNSLGLGLNSAAASGVLAA 311
           G AG  +  +     A    +G DLL  ST      S   +   L +    A    +L +
Sbjct: 118 GKAGTKIKEIRETTGAQVQVAG-DLLPNSTERAVTVSGVPDAIILCVRQICAV---ILES 173

Query: 312 VAAGA----NPAAAAAANLLASYAGEAGAGPAGGAAPPPPPPPGALGSFALAAAANGYLG 367
              GA    +P+ +    LL++  G +  G  G   P        L S A+         
Sbjct: 174 PPKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSSHAV--------- 224

Query: 368 AGAGGGAGGGGGPLVAAAAAAGAAGGFLTAEKLAAESAKELVEIAVPENLVGAILGKGGK 427
                       P    +   G   G  T+ +          E  VP +L+G ++G+ G 
Sbjct: 225 ------------PFATPSVVPGLDPGTQTSSQ----------EFLVPNDLIGCVIGRQGS 262

Query: 428 TLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQAAQYLIS 474
            + E ++++GA I+I  + E   G   R VTITGSP +   AQYLI+
Sbjct: 263 KISEIRQMSGAHIKIGNQAE---GAGERHVTITGSPVSIALAQYLIT 306



 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 100/405 (24%), Positives = 159/405 (39%), Gaps = 67/405 (16%)

Query: 35  LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNA 94
           L++L+     GSIIGK G+T+ ++++++ A I +S+         ER+  + G+  A+  
Sbjct: 20  LRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGS-----CPERITTITGSTAAVFH 74

Query: 95  VHSFIAEKVREIPQAMTKPEVVNILQPQTTMNPDRAKQAKLIVPNSTAGLIIGKGGATVK 154
             S IA K+ E           N+ +P  T+        +L++P S  G +IGK G  +K
Sbjct: 75  AVSMIAFKLDE-DLCAAPANGGNVSRPPVTL--------RLVIPASQCGSLIGKAGTKIK 125

Query: 155 AVMEQSGAWVQLSQK--PEGINLQERVVTVSGEPEQVHKAVSAIVQKVQEDPQSSSCL-- 210
            + E +GA VQ++    P   N  ER VTVSG P+ +   V  I   + E P   + +  
Sbjct: 126 EIRETTGAQVQVAGDLLP---NSTERAVTVSGVPDAIILCVRQICAVILESPPKGATIPY 182

Query: 211 ---------------NISYANVAGPVANSNPT--------GSPYASPADVLPAAAAASAA 247
                            S     G V  +  T          P+A+P+ V+P     +  
Sbjct: 183 HPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPFATPS-VVPGLDPGTQT 241

Query: 248 AASGLLGPAGLAGVGAFPAALPAFSGTDLLAISTALNTLASYGYNTNSLGLGLNSAAASG 307
           ++   L P  L G       +    G+ +  I          G    + G G      +G
Sbjct: 242 SSQEFLVPNDLIG------CVIGRQGSKISEIRQMSGAHIKIG--NQAEGAGERHVTITG 293

Query: 308 VLAAVAAGANPAAAAAANLLASYAGEAGAGPAGGAAPPPPP-------PPGALGSFALAA 360
              ++A       A      ++  G   + PA   AP  PP       PPG LG+   A 
Sbjct: 294 SPVSIALAQYLITACLETAKSTSGGTPSSAPADLPAPFSPPLTALPTAPPGLLGT-PYAI 352

Query: 361 AANGYLGAG-----AGGGAGGGGGP-LVAAAAAAGAAGGFLTAEK 399
           + + ++G       A   A  G  P L A  A   AA G   AE+
Sbjct: 353 SLSNFIGLKPMPFLALPPASPGPPPGLAAYTAKMAAANGSKKAER 397


>gi|14670369 poly(rC) binding protein 4 isoform c [Homo sapiens]
          Length = 403

 Score = 80.5 bits (197), Expect = 3e-15
 Identities = 91/347 (26%), Positives = 140/347 (40%), Gaps = 67/347 (19%)

Query: 134 KLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKAV 193
           ++++     G IIGK G TVK + EQS A + +S+     +  ER+ T++G    V  AV
Sbjct: 21  RMLMHGKEVGSIIGKKGETVKRIREQSSARITISEG----SCPERITTITGSTAAVFHAV 76

Query: 194 SAIVQKVQEDPQSSSCLNISYANVAGPVANSNPTGSPYASPADVLPAAAAASAAAASGLL 253
           S I  K+ ED             +    AN      P  +   V+PA+   S      L+
Sbjct: 77  SMIAFKLDED-------------LCAAPANGGNVSRPPVTLRLVIPASQCGS------LI 117

Query: 254 GPAG--LAGVGAFPAALPAFSGTDLLAISTALNTLASYGYNTNSLGLGLNSAAASGVLAA 311
           G AG  +  +     A    +G DLL  ST      S   +   L +    A    +L +
Sbjct: 118 GKAGTKIKEIRETTGAQVQVAG-DLLPNSTERAVTVSGVPDAIILCVRQICAV---ILES 173

Query: 312 VAAGA----NPAAAAAANLLASYAGEAGAGPAGGAAPPPPPPPGALGSFALAAAANGYLG 367
              GA    +P+ +    LL++  G +  G  G   P        L S A+         
Sbjct: 174 PPKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSSHAV--------- 224

Query: 368 AGAGGGAGGGGGPLVAAAAAAGAAGGFLTAEKLAAESAKELVEIAVPENLVGAILGKGGK 427
                       P    +   G   G  T+ +          E  VP +L+G ++G+ G 
Sbjct: 225 ------------PFATPSVVPGLDPGTQTSSQ----------EFLVPNDLIGCVIGRQGS 262

Query: 428 TLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQAAQYLIS 474
            + E ++++GA I+I  + E   G   R VTITGSP +   AQYLI+
Sbjct: 263 KISEIRQMSGAHIKIGNQAE---GAGERHVTITGSPVSIALAQYLIT 306



 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 100/405 (24%), Positives = 159/405 (39%), Gaps = 67/405 (16%)

Query: 35  LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNA 94
           L++L+     GSIIGK G+T+ ++++++ A I +S+         ER+  + G+  A+  
Sbjct: 20  LRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGS-----CPERITTITGSTAAVFH 74

Query: 95  VHSFIAEKVREIPQAMTKPEVVNILQPQTTMNPDRAKQAKLIVPNSTAGLIIGKGGATVK 154
             S IA K+ E           N+ +P  T+        +L++P S  G +IGK G  +K
Sbjct: 75  AVSMIAFKLDE-DLCAAPANGGNVSRPPVTL--------RLVIPASQCGSLIGKAGTKIK 125

Query: 155 AVMEQSGAWVQLSQK--PEGINLQERVVTVSGEPEQVHKAVSAIVQKVQEDPQSSSCL-- 210
            + E +GA VQ++    P   N  ER VTVSG P+ +   V  I   + E P   + +  
Sbjct: 126 EIRETTGAQVQVAGDLLP---NSTERAVTVSGVPDAIILCVRQICAVILESPPKGATIPY 182

Query: 211 ---------------NISYANVAGPVANSNPT--------GSPYASPADVLPAAAAASAA 247
                            S     G V  +  T          P+A+P+ V+P     +  
Sbjct: 183 HPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPFATPS-VVPGLDPGTQT 241

Query: 248 AASGLLGPAGLAGVGAFPAALPAFSGTDLLAISTALNTLASYGYNTNSLGLGLNSAAASG 307
           ++   L P  L G       +    G+ +  I          G    + G G      +G
Sbjct: 242 SSQEFLVPNDLIG------CVIGRQGSKISEIRQMSGAHIKIG--NQAEGAGERHVTITG 293

Query: 308 VLAAVAAGANPAAAAAANLLASYAGEAGAGPAGGAAPPPPP-------PPGALGSFALAA 360
              ++A       A      ++  G   + PA   AP  PP       PPG LG+   A 
Sbjct: 294 SPVSIALAQYLITACLETAKSTSGGTPSSAPADLPAPFSPPLTALPTAPPGLLGT-PYAI 352

Query: 361 AANGYLGAG-----AGGGAGGGGGP-LVAAAAAAGAAGGFLTAEK 399
           + + ++G       A   A  G  P L A  A   AA G   AE+
Sbjct: 353 SLSNFIGLKPMPFLALPPASPGPPPGLAAYTAKMAAANGSKKAER 397


>gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens]
          Length = 345

 Score = 79.0 bits (193), Expect = 9e-15
 Identities = 56/179 (31%), Positives = 93/179 (51%), Gaps = 23/179 (12%)

Query: 22  TKRSNTGEEGEYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTER 81
           +K S  G      +++L+     GSIIGK G+T+ ++++E+GA I +S+         ER
Sbjct: 35  SKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGN-----CPER 89

Query: 82  VCLVQGTAEALNAVHSFIAEKVREIPQAMTKPEVVNILQ--PQTTMNPDRAKQAKLIVPN 139
           +  + G  +A+    + IA K  E        +++N +   P T+  P      +L+VP 
Sbjct: 90  IVTITGPTDAIFKAFAMIAYKFEE--------DIINSMSNSPATSKPP---VTLRLVVPA 138

Query: 140 STAGLIIGKGGATVKAVMEQSGAWVQLS--QKPEGINLQERVVTVSGEPEQVHKAVSAI 196
           S  G +IGKGG+ +K + E +GA VQ++    P   N  ER VT+SG P+ + + V  I
Sbjct: 139 SQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLP---NSTERAVTISGTPDAIIQCVKQI 194



 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 48/200 (24%), Positives = 88/200 (44%), Gaps = 46/200 (23%)

Query: 35  LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEA--- 91
           L++++P+   GS+IGKGG  I ++++ TGA ++++   D  P +TER   + GT +A   
Sbjct: 132 LRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAG--DMLPNSTERAVTISGTPDAIIQ 189

Query: 92  -------------------------LNAVHSFIAEKVREIPQAMTKP------------- 113
                                    L  +H    ++    P   T P             
Sbjct: 190 CVKQICVVMLEAYTIQGQYAIPHPDLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSE 249

Query: 114 EVVNILQPQTTMNPDR-AKQAKLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEG 172
           E  N++   + ++    A   +L +PN   G IIG+ G  +  + + SGA ++++   EG
Sbjct: 250 EAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEG 309

Query: 173 INLQERVVTVSGEPEQVHKA 192
            +  ER +T++G P  +  A
Sbjct: 310 SS--ERQITITGTPANISLA 327



 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 29/71 (40%), Positives = 49/71 (69%), Gaps = 3/71 (4%)

Query: 410 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQAA 469
           E+ +P +L+G I+G+ G  + E ++++GA+I+I+   E   G+  R++TITG+PA    A
Sbjct: 271 ELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATE---GSSERQITITGTPANISLA 327

Query: 470 QYLISQRVTYE 480
           QYLI+ R+T E
Sbjct: 328 QYLINARLTSE 338



 Score = 55.8 bits (133), Expect = 9e-08
 Identities = 36/118 (30%), Positives = 57/118 (48%), Gaps = 17/118 (14%)

Query: 134 KLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKAV 193
           +L++     G IIGK G TVK + E+SGA + +S+     N  ER+VT++G  + + KA 
Sbjct: 49  RLLMHGKEVGSIIGKKGETVKKMREESGARINISEG----NCPERIVTITGPTDAIFKAF 104

Query: 194 SAIVQKVQEDPQSSSCLNISYANVAGPVANSNPTGSPYASPADVLPAAAAASAAAASG 251
           + I  K +ED             +   ++NS  T  P  +   V+PA+   S     G
Sbjct: 105 AMIAYKFEED-------------IINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGG 149



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 23/57 (40%), Positives = 39/57 (68%), Gaps = 2/57 (3%)

Query: 409 VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAA 465
           + + VP +  G+++GKGG  + E +E TGA++Q++  G+ LP +  R VTI+G+P A
Sbjct: 132 LRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVA--GDMLPNSTERAVTISGTPDA 186



 Score = 33.9 bits (76), Expect = 0.35
 Identities = 23/59 (38%), Positives = 34/59 (57%), Gaps = 5/59 (8%)

Query: 418 VGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQAAQYLISQR 476
           VG+I+GK G+T+ + +E +GARI IS+          R VTITG   A   A  +I+ +
Sbjct: 57  VGSIIGKKGETVKKMREESGARINISE-----GNCPERIVTITGPTDAIFKAFAMIAYK 110


>gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens]
          Length = 362

 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 81/313 (25%), Positives = 133/313 (42%), Gaps = 34/313 (10%)

Query: 35  LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNA 94
           +++L+     GSIIGK G+++ ++++E+GA I +S+         ER+  + G   A+  
Sbjct: 16  IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAIFK 70

Query: 95  VHSFIAEKVRE-IPQAMTKPEVVNILQPQTTMNPDRAKQAKLIVPNSTAGLIIGKGGATV 153
             + I +K+ E I  +MT     +  +P  T+        +L+VP S  G +IGKGG  +
Sbjct: 71  AFAMIIDKLEEDISSSMTNSTAAS--RPPVTL--------RLVVPASQCGSLIGKGGCKI 120

Query: 154 KAVMEQSGAWVQLS--QKPEGINLQERVVTVSGEPEQVHKAVSAIVQKVQEDPQSSSCLN 211
           K + E +GA VQ++    P   N  ER +T++G P+ + + V  I   + E P     + 
Sbjct: 121 KEIRESTGAQVQVAGDMLP---NSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIP 177

Query: 212 ISYANVAGPV-----ANSNPTGSPYASPADVLPAAAAASAAAASGLLGPAGLAGVGAFPA 266
                 + PV      +   TGS  AS     P     S      L GP   A       
Sbjct: 178 YRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTP-----SMCLNPDLEGPPLEAYTIQGQY 232

Query: 267 ALPAFSGTDLLAISTALNTLASYGYNTNSLGLGLNSAAASGVLAAVAAGANPAA---AAA 323
           A+P    T L  ++   +       NT   G+  +S    G  A + A A   +      
Sbjct: 233 AIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIP 292

Query: 324 ANLLASYAGEAGA 336
            +L+    G  GA
Sbjct: 293 NDLIGCIIGRQGA 305



 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 31/78 (39%), Positives = 53/78 (67%), Gaps = 3/78 (3%)

Query: 410 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQAA 469
           E+ +P +L+G I+G+ G  + E ++++GA+I+I+   E   G+ +R+VTITGS A+   A
Sbjct: 288 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE---GSTDRQVTITGSAASISLA 344

Query: 470 QYLISQRVTYEQGVRASN 487
           QYLI+ R++ E G   S+
Sbjct: 345 QYLINVRLSSETGGMGSS 362



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 23/63 (36%), Positives = 38/63 (60%), Gaps = 2/63 (3%)

Query: 401 AAESAKELVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTIT 460
           AA      + + VP +  G+++GKGG  + E +E TGA++Q++  G+ LP +  R +TI 
Sbjct: 92  AASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVA--GDMLPNSTERAITIA 149

Query: 461 GSP 463
           G P
Sbjct: 150 GIP 152



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 19/59 (32%), Positives = 33/59 (55%), Gaps = 2/59 (3%)

Query: 134 KLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKA 192
           +L +PN   G IIG+ GA +  + + SGA ++++   EG    +R VT++G    +  A
Sbjct: 288 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGST--DRQVTITGSAASISLA 344



 Score = 33.5 bits (75), Expect = 0.45
 Identities = 18/64 (28%), Positives = 37/64 (57%), Gaps = 3/64 (4%)

Query: 36  KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNAV 95
           ++ IP+   G IIG+ G  I ++++ +GA IK++   +   G+T+R   + G+A +++  
Sbjct: 288 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE---GSTDRQVTITGSAASISLA 344

Query: 96  HSFI 99
              I
Sbjct: 345 QYLI 348



 Score = 29.6 bits (65), Expect = 6.5
 Identities = 13/27 (48%), Positives = 22/27 (81%)

Query: 418 VGAILGKGGKTLVEYQELTGARIQISK 444
           VG+I+GK G+++ + +E +GARI IS+
Sbjct: 25  VGSIIGKKGESVKKMREESGARINISE 51


>gi|56118219 insulin-like growth factor 2 mRNA binding protein 2
           isoform b [Homo sapiens]
          Length = 556

 Score = 77.4 bits (189), Expect = 3e-14
 Identities = 57/198 (28%), Positives = 93/198 (46%), Gaps = 13/198 (6%)

Query: 18  EVVCTKRSNTGEEGEYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPG 77
           E++  +   T    E  LK+L  +   G +IGK G+ + +++ ETG  I +S  +D    
Sbjct: 260 EIMQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIY 319

Query: 78  TTERVCLVQGTAEALNAVHSFIAEKVRE-----IPQAMTKPEVVNILQPQTTMNP----- 127
             ER   V+GT EA  +    I +K+RE     +    T     + L P     P     
Sbjct: 320 NPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNTHSGYFSSLYPHHQFGPFPHHH 379

Query: 128 --DRAKQAKLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGE 185
                +   L +P    G IIGK GA +K +   +GA ++++   EG ++ ER+V ++G 
Sbjct: 380 SYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIA-PAEGPDVSERMVIITGP 438

Query: 186 PEQVHKAVSAIVQKVQED 203
           PE   KA   I  K++E+
Sbjct: 439 PEAQFKAQGRIFGKLKEE 456



 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 51/174 (29%), Positives = 86/174 (49%), Gaps = 19/174 (10%)

Query: 35  LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNA 94
           + + IP+ A G+IIGK G  I QL +  GA+IK++ ++   P  +ER+ ++ G  EA   
Sbjct: 387 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEG--PDVSERMVIITGPPEAQFK 444

Query: 95  VHSFIAEKVREIPQAMTKPEVVNILQPQTTMNPDRAKQAKLIVPNSTAGLIIGKGGATVK 154
               I  K++E           N   P+  +      +A + VP+STAG +IGKGG TV 
Sbjct: 445 AQGRIFGKLKE----------ENFFNPKEEVK----LEAHIRVPSSTAGRVIGKGGKTVN 490

Query: 155 AVMEQSGAWVQLSQKPEGINLQERVVTVSGE---PEQVHKAVSAIVQKVQEDPQ 205
            +   + A V + +       +E +V + G     +   + +  IVQ+V++  Q
Sbjct: 491 ELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQ 544



 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 44/172 (25%), Positives = 80/172 (46%), Gaps = 18/172 (10%)

Query: 32  EYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEA 91
           ++ L++L+P+   G+IIGK G TI  + K+T + + + + ++   G  E+   +  T E 
Sbjct: 193 DFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKEN--SGAAEKPVTIHATPEG 250

Query: 92  LNAVHSFIAEKVREIPQAMTKPEVVNILQPQTTMNPDRAKQAKLIVPNSTAGLIIGKGGA 151
                   +E  R I + M K      L  +  +        K++  N   G +IGK G 
Sbjct: 251 -------TSEACRMILEIMQKEADETKLAEEIPL--------KILAHNGLVGRLIGKEGR 295

Query: 152 TVKAVMEQSGAWVQLSQKPE-GINLQERVVTVSGEPEQVHKAVSAIVQKVQE 202
            +K +  ++G  + +S   +  I   ER +TV G  E    A   I++K++E
Sbjct: 296 NLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLRE 347



 Score = 42.7 bits (99), Expect = 7e-04
 Identities = 38/115 (33%), Positives = 48/115 (41%), Gaps = 3/115 (2%)

Query: 379 GPLVAAAAAAGAAGGFLTAEKL--AAESAKELVEIAVPENLVGAILGKGGKTLVEYQELT 436
           GP  A   A G   G L  E      E  K    I VP +  G ++GKGGKT+ E Q LT
Sbjct: 437 GPPEAQFKAQGRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLT 496

Query: 437 GARIQISKKGEFLPGTRNRRVTITGSPAATQAAQYLISQRVTYEQGVRASNPQKV 491
            A + I  + +         V I G   A+Q AQ  I + V   +      PQ V
Sbjct: 497 SAEV-IVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQKYPQGV 550



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 24/65 (36%), Positives = 33/65 (50%), Gaps = 2/65 (3%)

Query: 406 KELVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAA 465
           +E+V + +P   VGAI+GK G  + +     GA I+I+      P    R V ITG P A
Sbjct: 384 QEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEG--PDVSERMVIITGPPEA 441

Query: 466 TQAAQ 470
              AQ
Sbjct: 442 QFKAQ 446



 Score = 38.5 bits (88), Expect = 0.014
 Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 3/88 (3%)

Query: 26  NTGEEGEYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCL- 84
           N  EE +    + +PS  AG +IGKGG+T+ +LQ  T A + +   +D  P   E V + 
Sbjct: 460 NPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIV--PRDQTPDENEEVIVR 517

Query: 85  VQGTAEALNAVHSFIAEKVREIPQAMTK 112
           + G   A       I E V+++ Q   K
Sbjct: 518 IIGHFFASQTAQRKIREIVQQVKQQEQK 545



 Score = 38.1 bits (87), Expect = 0.018
 Identities = 23/65 (35%), Positives = 33/65 (50%), Gaps = 2/65 (3%)

Query: 409 VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQA 468
           + I VP   VGAI+GK G T+    + T +R+ I +K     G   + VTI  +P  T  
Sbjct: 196 LRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKEN--SGAAEKPVTIHATPEGTSE 253

Query: 469 AQYLI 473
           A  +I
Sbjct: 254 ACRMI 258



 Score = 35.8 bits (81), Expect = 0.091
 Identities = 23/81 (28%), Positives = 40/81 (49%), Gaps = 2/81 (2%)

Query: 409 VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQA 468
           ++I     LVG ++GK G+ L + +  TG +I IS   +       R +T+ G+  A  +
Sbjct: 277 LKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACAS 336

Query: 469 AQYLISQ--RVTYEQGVRASN 487
           A+  I +  R  +E  + A N
Sbjct: 337 AEIEIMKKLREAFENDMLAVN 357


>gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens]
          Length = 318

 Score = 77.0 bits (188), Expect = 4e-14
 Identities = 52/173 (30%), Positives = 91/173 (52%), Gaps = 21/173 (12%)

Query: 35  LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNA 94
           +++L+     GSIIGK G+++ ++++E+GA I +S+         ER+  + G   A+  
Sbjct: 16  IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAIFK 70

Query: 95  VHSFIAEKVRE-IPQAMTKPEVVNILQPQTTMNPDRAKQAKLIVPNSTAGLIIGKGGATV 153
             + I +K+ E I  +MT     +  +P  T+        +L+VP S  G +IGKGG  +
Sbjct: 71  AFAMIIDKLEEDISSSMTNSTAAS--RPPVTL--------RLVVPASQCGSLIGKGGCKI 120

Query: 154 KAVMEQSGAWVQLS--QKPEGINLQERVVTVSGEPEQVHKAVSAIVQKVQEDP 204
           K + E +GA VQ++    P   N  ER +T++G P+ + + V  I   + E P
Sbjct: 121 KEIRESTGAQVQVAGDMLP---NSTERAITIAGIPQSIIECVKQICVVMLESP 170



 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 31/78 (39%), Positives = 53/78 (67%), Gaps = 3/78 (3%)

Query: 410 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQAA 469
           E+ +P +L+G I+G+ G  + E ++++GA+I+I+   E   G+ +R+VTITGS A+   A
Sbjct: 244 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE---GSTDRQVTITGSAASISLA 300

Query: 470 QYLISQRVTYEQGVRASN 487
           QYLI+ R++ E G   S+
Sbjct: 301 QYLINVRLSSETGGMGSS 318



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 49/205 (23%), Positives = 89/205 (43%), Gaps = 51/205 (24%)

Query: 35  LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNA 94
           L++++P+   GS+IGKGG  I ++++ TGA ++++   D  P +TER   + G  +++  
Sbjct: 100 LRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAG--DMLPNSTERAITIAGIPQSIIE 157

Query: 95  VHSFIAEKVREIPQ------------------------------AMTKPEVVNILQ---- 120
               I   + E P                               A+ +P++  + Q    
Sbjct: 158 CVKQICVVMLESPPKGVTIPYRPKPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQ 217

Query: 121 ----PQTTMNP------DRAKQA---KLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLS 167
               P T  N       D + Q    +L +PN   G IIG+ GA +  + + SGA ++++
Sbjct: 218 QSHFPMTHGNTGFSAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIA 277

Query: 168 QKPEGINLQERVVTVSGEPEQVHKA 192
              EG    +R VT++G    +  A
Sbjct: 278 NPVEGST--DRQVTITGSAASISLA 300



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 35/118 (29%), Positives = 57/118 (48%), Gaps = 17/118 (14%)

Query: 134 KLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKAV 193
           +L++     G IIGK G +VK + E+SGA + +S+     N  ER++T++G    + KA 
Sbjct: 17  RLLMHGKEVGSIIGKKGESVKKMREESGARINISEG----NCPERIITLAGPTNAIFKAF 72

Query: 194 SAIVQKVQEDPQSSSCLNISYANVAGPVANSNPTGSPYASPADVLPAAAAASAAAASG 251
           + I+ K++ED  SS             + NS     P  +   V+PA+   S     G
Sbjct: 73  AMIIDKLEEDISSS-------------MTNSTAASRPPVTLRLVVPASQCGSLIGKGG 117



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 23/63 (36%), Positives = 38/63 (60%), Gaps = 2/63 (3%)

Query: 401 AAESAKELVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTIT 460
           AA      + + VP +  G+++GKGG  + E +E TGA++Q++  G+ LP +  R +TI 
Sbjct: 92  AASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVA--GDMLPNSTERAITIA 149

Query: 461 GSP 463
           G P
Sbjct: 150 GIP 152



 Score = 33.5 bits (75), Expect = 0.45
 Identities = 18/64 (28%), Positives = 37/64 (57%), Gaps = 3/64 (4%)

Query: 36  KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNAV 95
           ++ IP+   G IIG+ G  I ++++ +GA IK++   +   G+T+R   + G+A +++  
Sbjct: 244 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE---GSTDRQVTITGSAASISLA 300

Query: 96  HSFI 99
              I
Sbjct: 301 QYLI 304



 Score = 29.6 bits (65), Expect = 6.5
 Identities = 13/27 (48%), Positives = 22/27 (81%)

Query: 418 VGAILGKGGKTLVEYQELTGARIQISK 444
           VG+I+GK G+++ + +E +GARI IS+
Sbjct: 25  VGSIIGKKGESVKKMREESGARINISE 51


>gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens]
          Length = 361

 Score = 77.0 bits (188), Expect = 4e-14
 Identities = 52/173 (30%), Positives = 91/173 (52%), Gaps = 21/173 (12%)

Query: 35  LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNA 94
           +++L+     GSIIGK G+++ ++++E+GA I +S+         ER+  + G   A+  
Sbjct: 16  IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAIFK 70

Query: 95  VHSFIAEKVRE-IPQAMTKPEVVNILQPQTTMNPDRAKQAKLIVPNSTAGLIIGKGGATV 153
             + I +K+ E I  +MT     +  +P  T+        +L+VP S  G +IGKGG  +
Sbjct: 71  AFAMIIDKLEEDISSSMTNSTAAS--RPPVTL--------RLVVPASQCGSLIGKGGCKI 120

Query: 154 KAVMEQSGAWVQLS--QKPEGINLQERVVTVSGEPEQVHKAVSAIVQKVQEDP 204
           K + E +GA VQ++    P   N  ER +T++G P+ + + V  I   + E P
Sbjct: 121 KEIRESTGAQVQVAGDMLP---NSTERAITIAGIPQSIIECVKQICVVMLESP 170



 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 31/78 (39%), Positives = 53/78 (67%), Gaps = 3/78 (3%)

Query: 410 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQAA 469
           E+ +P +L+G I+G+ G  + E ++++GA+I+I+   E   G+ +R+VTITGS A+   A
Sbjct: 287 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE---GSTDRQVTITGSAASISLA 343

Query: 470 QYLISQRVTYEQGVRASN 487
           QYLI+ R++ E G   S+
Sbjct: 344 QYLINVRLSSETGGMGSS 361



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 35/118 (29%), Positives = 57/118 (48%), Gaps = 17/118 (14%)

Query: 134 KLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKAV 193
           +L++     G IIGK G +VK + E+SGA + +S+     N  ER++T++G    + KA 
Sbjct: 17  RLLMHGKEVGSIIGKKGESVKKMREESGARINISEG----NCPERIITLAGPTNAIFKAF 72

Query: 194 SAIVQKVQEDPQSSSCLNISYANVAGPVANSNPTGSPYASPADVLPAAAAASAAAASG 251
           + I+ K++ED  SS             + NS     P  +   V+PA+   S     G
Sbjct: 73  AMIIDKLEEDISSS-------------MTNSTAASRPPVTLRLVVPASQCGSLIGKGG 117



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 23/63 (36%), Positives = 38/63 (60%), Gaps = 2/63 (3%)

Query: 401 AAESAKELVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTIT 460
           AA      + + VP +  G+++GKGG  + E +E TGA++Q++  G+ LP +  R +TI 
Sbjct: 92  AASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVA--GDMLPNSTERAITIA 149

Query: 461 GSP 463
           G P
Sbjct: 150 GIP 152



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 19/59 (32%), Positives = 33/59 (55%), Gaps = 2/59 (3%)

Query: 134 KLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKA 192
           +L +PN   G IIG+ GA +  + + SGA ++++   EG    +R VT++G    +  A
Sbjct: 287 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGST--DRQVTITGSAASISLA 343



 Score = 33.5 bits (75), Expect = 0.45
 Identities = 18/64 (28%), Positives = 37/64 (57%), Gaps = 3/64 (4%)

Query: 36  KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNAV 95
           ++ IP+   G IIG+ G  I ++++ +GA IK++   +   G+T+R   + G+A +++  
Sbjct: 287 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE---GSTDRQVTITGSAASISLA 343

Query: 96  HSFI 99
              I
Sbjct: 344 QYLI 347



 Score = 29.6 bits (65), Expect = 6.5
 Identities = 13/27 (48%), Positives = 22/27 (81%)

Query: 418 VGAILGKGGKTLVEYQELTGARIQISK 444
           VG+I+GK G+++ + +E +GARI IS+
Sbjct: 25  VGSIIGKKGESVKKMREESGARINISE 51


>gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens]
          Length = 331

 Score = 77.0 bits (188), Expect = 4e-14
 Identities = 52/173 (30%), Positives = 91/173 (52%), Gaps = 21/173 (12%)

Query: 35  LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNA 94
           +++L+     GSIIGK G+++ ++++E+GA I +S+         ER+  + G   A+  
Sbjct: 16  IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAIFK 70

Query: 95  VHSFIAEKVRE-IPQAMTKPEVVNILQPQTTMNPDRAKQAKLIVPNSTAGLIIGKGGATV 153
             + I +K+ E I  +MT     +  +P  T+        +L+VP S  G +IGKGG  +
Sbjct: 71  AFAMIIDKLEEDISSSMTNSTAAS--RPPVTL--------RLVVPASQCGSLIGKGGCKI 120

Query: 154 KAVMEQSGAWVQLS--QKPEGINLQERVVTVSGEPEQVHKAVSAIVQKVQEDP 204
           K + E +GA VQ++    P   N  ER +T++G P+ + + V  I   + E P
Sbjct: 121 KEIRESTGAQVQVAGDMLP---NSTERAITIAGIPQSIIECVKQICVVMLESP 170



 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 31/78 (39%), Positives = 53/78 (67%), Gaps = 3/78 (3%)

Query: 410 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQAA 469
           E+ +P +L+G I+G+ G  + E ++++GA+I+I+   E   G+ +R+VTITGS A+   A
Sbjct: 257 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE---GSTDRQVTITGSAASISLA 313

Query: 470 QYLISQRVTYEQGVRASN 487
           QYLI+ R++ E G   S+
Sbjct: 314 QYLINVRLSSETGGMGSS 331



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 35/118 (29%), Positives = 57/118 (48%), Gaps = 17/118 (14%)

Query: 134 KLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKAV 193
           +L++     G IIGK G +VK + E+SGA + +S+     N  ER++T++G    + KA 
Sbjct: 17  RLLMHGKEVGSIIGKKGESVKKMREESGARINISEG----NCPERIITLAGPTNAIFKAF 72

Query: 194 SAIVQKVQEDPQSSSCLNISYANVAGPVANSNPTGSPYASPADVLPAAAAASAAAASG 251
           + I+ K++ED  SS             + NS     P  +   V+PA+   S     G
Sbjct: 73  AMIIDKLEEDISSS-------------MTNSTAASRPPVTLRLVVPASQCGSLIGKGG 117



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 23/63 (36%), Positives = 38/63 (60%), Gaps = 2/63 (3%)

Query: 401 AAESAKELVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTIT 460
           AA      + + VP +  G+++GKGG  + E +E TGA++Q++  G+ LP +  R +TI 
Sbjct: 92  AASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVA--GDMLPNSTERAITIA 149

Query: 461 GSP 463
           G P
Sbjct: 150 GIP 152



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 19/59 (32%), Positives = 33/59 (55%), Gaps = 2/59 (3%)

Query: 134 KLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKA 192
           +L +PN   G IIG+ GA +  + + SGA ++++   EG    +R VT++G    +  A
Sbjct: 257 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGST--DRQVTITGSAASISLA 313



 Score = 33.5 bits (75), Expect = 0.45
 Identities = 18/64 (28%), Positives = 37/64 (57%), Gaps = 3/64 (4%)

Query: 36  KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNAV 95
           ++ IP+   G IIG+ G  I ++++ +GA IK++   +   G+T+R   + G+A +++  
Sbjct: 257 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE---GSTDRQVTITGSAASISLA 313

Query: 96  HSFI 99
              I
Sbjct: 314 QYLI 317



 Score = 29.6 bits (65), Expect = 6.5
 Identities = 13/27 (48%), Positives = 22/27 (81%)

Query: 418 VGAILGKGGKTLVEYQELTGARIQISK 444
           VG+I+GK G+++ + +E +GARI IS+
Sbjct: 25  VGSIIGKKGESVKKMREESGARINISE 51


>gi|222352151 poly(rC) binding protein 1 [Homo sapiens]
          Length = 356

 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 52/178 (29%), Positives = 94/178 (52%), Gaps = 25/178 (14%)

Query: 35  LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNA 94
           +++L+     GSIIGK G+++ ++++E+GA I +S+         ER+  + G   A+  
Sbjct: 16  IRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGN-----CPERIITLTGPTNAIFK 70

Query: 95  VHSFIAEKVRE-IPQAMTKPEVVNILQPQTTMNPDRAKQAKLIVPNSTAGLIIGKGGATV 153
             + I +K+ E I  +MT     +  +P  T+        +L+VP +  G +IGKGG  +
Sbjct: 71  AFAMIIDKLEEDINSSMTNSTAAS--RPPVTL--------RLVVPATQCGSLIGKGGCKI 120

Query: 154 KAVMEQSGAWVQLS--QKPEGINLQERVVTVSGEPEQVHKAVSAI----VQKVQEDPQ 205
           K + E +GA VQ++    P   N  ER +T++G P+ V + V  I    ++ + + PQ
Sbjct: 121 KEIRESTGAQVQVAGDMLP---NSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQ 175



 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 32/77 (41%), Positives = 53/77 (68%), Gaps = 3/77 (3%)

Query: 410 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQAA 469
           E+ +P NL+G I+G+ G  + E ++++GA+I+I+   E   G+  R+VTITGS A+   A
Sbjct: 283 ELTIPNNLIGCIIGRQGANINEIRQMSGAQIKIANPVE---GSSGRQVTITGSAASISLA 339

Query: 470 QYLISQRVTYEQGVRAS 486
           QYLI+ R++ E+G+  S
Sbjct: 340 QYLINARLSSEKGMGCS 356



 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 35/118 (29%), Positives = 56/118 (47%), Gaps = 17/118 (14%)

Query: 134 KLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKAV 193
           +L++     G IIGK G +VK + E+SGA + +S+     N  ER++T++G    + KA 
Sbjct: 17  RLLMHGKEVGSIIGKKGESVKRIREESGARINISEG----NCPERIITLTGPTNAIFKAF 72

Query: 194 SAIVQKVQEDPQSSSCLNISYANVAGPVANSNPTGSPYASPADVLPAAAAASAAAASG 251
           + I+ K++ED  SS             + NS     P  +   V+PA    S     G
Sbjct: 73  AMIIDKLEEDINSS-------------MTNSTAASRPPVTLRLVVPATQCGSLIGKGG 117



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 23/63 (36%), Positives = 37/63 (58%), Gaps = 2/63 (3%)

Query: 401 AAESAKELVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTIT 460
           AA      + + VP    G+++GKGG  + E +E TGA++Q++  G+ LP +  R +TI 
Sbjct: 92  AASRPPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVA--GDMLPNSTERAITIA 149

Query: 461 GSP 463
           G P
Sbjct: 150 GVP 152



 Score = 38.9 bits (89), Expect = 0.011
 Identities = 19/59 (32%), Positives = 34/59 (57%), Gaps = 2/59 (3%)

Query: 134 KLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKA 192
           +L +PN+  G IIG+ GA +  + + SGA ++++   EG +   R VT++G    +  A
Sbjct: 283 ELTIPNNLIGCIIGRQGANINEIRQMSGAQIKIANPVEGSS--GRQVTITGSAASISLA 339



 Score = 31.2 bits (69), Expect = 2.2
 Identities = 17/64 (26%), Positives = 36/64 (56%), Gaps = 3/64 (4%)

Query: 36  KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNAV 95
           ++ IP+   G IIG+ G  I ++++ +GA IK++   +   G++ R   + G+A +++  
Sbjct: 283 ELTIPNNLIGCIIGRQGANINEIRQMSGAQIKIANPVE---GSSGRQVTITGSAASISLA 339

Query: 96  HSFI 99
              I
Sbjct: 340 QYLI 343



 Score = 30.8 bits (68), Expect = 2.9
 Identities = 22/69 (31%), Positives = 38/69 (55%), Gaps = 7/69 (10%)

Query: 418 VGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQAAQYLISQRV 477
           VG+I+GK G+++   +E +GARI IS+          R +T+TG   A   A  +I  ++
Sbjct: 25  VGSIIGKKGESVKRIREESGARINISE-----GNCPERIITLTGPTNAIFKAFAMIIDKL 79

Query: 478 TYEQGVRAS 486
             E+ + +S
Sbjct: 80  --EEDINSS 86


>gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens]
          Length = 335

 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 50/165 (30%), Positives = 88/165 (53%), Gaps = 21/165 (12%)

Query: 35  LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNA 94
           +++L+     GSIIGK G+++ ++++E+GA I +S+         ER+  + G   A+  
Sbjct: 16  IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAIFK 70

Query: 95  VHSFIAEKVRE-IPQAMTKPEVVNILQPQTTMNPDRAKQAKLIVPNSTAGLIIGKGGATV 153
             + I +K+ E I  +MT     +  +P  T+        +L+VP S  G +IGKGG  +
Sbjct: 71  AFAMIIDKLEEDISSSMTNSTAAS--RPPVTL--------RLVVPASQCGSLIGKGGCKI 120

Query: 154 KAVMEQSGAWVQLS--QKPEGINLQERVVTVSGEPEQVHKAVSAI 196
           K + E +GA VQ++    P   N  ER +T++G P+ + + V  I
Sbjct: 121 KEIRESTGAQVQVAGDMLP---NSTERAITIAGIPQSIIECVKQI 162



 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 31/78 (39%), Positives = 53/78 (67%), Gaps = 3/78 (3%)

Query: 410 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQAA 469
           E+ +P +L+G I+G+ G  + E ++++GA+I+I+   E   G+ +R+VTITGS A+   A
Sbjct: 261 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE---GSTDRQVTITGSAASISLA 317

Query: 470 QYLISQRVTYEQGVRASN 487
           QYLI+ R++ E G   S+
Sbjct: 318 QYLINVRLSSETGGMGSS 335



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 35/118 (29%), Positives = 57/118 (48%), Gaps = 17/118 (14%)

Query: 134 KLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKAV 193
           +L++     G IIGK G +VK + E+SGA + +S+     N  ER++T++G    + KA 
Sbjct: 17  RLLMHGKEVGSIIGKKGESVKKMREESGARINISEG----NCPERIITLAGPTNAIFKAF 72

Query: 194 SAIVQKVQEDPQSSSCLNISYANVAGPVANSNPTGSPYASPADVLPAAAAASAAAASG 251
           + I+ K++ED  SS             + NS     P  +   V+PA+   S     G
Sbjct: 73  AMIIDKLEEDISSS-------------MTNSTAASRPPVTLRLVVPASQCGSLIGKGG 117



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 49/222 (22%), Positives = 90/222 (40%), Gaps = 68/222 (30%)

Query: 35  LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLV----QGTAE 90
           L++++P+   GS+IGKGG  I ++++ TGA ++++   D  P +TER   +    Q   E
Sbjct: 100 LRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAG--DMLPNSTERAITIAGIPQSIIE 157

Query: 91  ALNAVHSFIAEKVREIPQ------------------------------AMTKPEVVNILQ 120
            +  +   + E + + P                               A+ +P++  + Q
Sbjct: 158 CVKQICVVMLETLSQSPPKGVTIPYRPKPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQ 217

Query: 121 --------PQTTMNP-------------------DRAKQA---KLIVPNSTAGLIIGKGG 150
                   P T  N                    D + Q    +L +PN   G IIG+ G
Sbjct: 218 LAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQG 277

Query: 151 ATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKA 192
           A +  + + SGA ++++   EG    +R VT++G    +  A
Sbjct: 278 AKINEIRQMSGAQIKIANPVEGST--DRQVTITGSAASISLA 317



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 23/63 (36%), Positives = 38/63 (60%), Gaps = 2/63 (3%)

Query: 401 AAESAKELVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTIT 460
           AA      + + VP +  G+++GKGG  + E +E TGA++Q++  G+ LP +  R +TI 
Sbjct: 92  AASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVA--GDMLPNSTERAITIA 149

Query: 461 GSP 463
           G P
Sbjct: 150 GIP 152



 Score = 33.5 bits (75), Expect = 0.45
 Identities = 18/64 (28%), Positives = 37/64 (57%), Gaps = 3/64 (4%)

Query: 36  KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNAV 95
           ++ IP+   G IIG+ G  I ++++ +GA IK++   +   G+T+R   + G+A +++  
Sbjct: 261 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE---GSTDRQVTITGSAASISLA 317

Query: 96  HSFI 99
              I
Sbjct: 318 QYLI 321



 Score = 29.6 bits (65), Expect = 6.5
 Identities = 13/27 (48%), Positives = 22/27 (81%)

Query: 418 VGAILGKGGKTLVEYQELTGARIQISK 444
           VG+I+GK G+++ + +E +GARI IS+
Sbjct: 25  VGSIIGKKGESVKKMREESGARINISE 51


>gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens]
          Length = 365

 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 50/165 (30%), Positives = 88/165 (53%), Gaps = 21/165 (12%)

Query: 35  LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNA 94
           +++L+     GSIIGK G+++ ++++E+GA I +S+         ER+  + G   A+  
Sbjct: 16  IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAIFK 70

Query: 95  VHSFIAEKVRE-IPQAMTKPEVVNILQPQTTMNPDRAKQAKLIVPNSTAGLIIGKGGATV 153
             + I +K+ E I  +MT     +  +P  T+        +L+VP S  G +IGKGG  +
Sbjct: 71  AFAMIIDKLEEDISSSMTNSTAAS--RPPVTL--------RLVVPASQCGSLIGKGGCKI 120

Query: 154 KAVMEQSGAWVQLS--QKPEGINLQERVVTVSGEPEQVHKAVSAI 196
           K + E +GA VQ++    P   N  ER +T++G P+ + + V  I
Sbjct: 121 KEIRESTGAQVQVAGDMLP---NSTERAITIAGIPQSIIECVKQI 162



 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 31/78 (39%), Positives = 53/78 (67%), Gaps = 3/78 (3%)

Query: 410 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQAA 469
           E+ +P +L+G I+G+ G  + E ++++GA+I+I+   E   G+ +R+VTITGS A+   A
Sbjct: 291 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE---GSTDRQVTITGSAASISLA 347

Query: 470 QYLISQRVTYEQGVRASN 487
           QYLI+ R++ E G   S+
Sbjct: 348 QYLINVRLSSETGGMGSS 365



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 35/118 (29%), Positives = 57/118 (48%), Gaps = 17/118 (14%)

Query: 134 KLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKAV 193
           +L++     G IIGK G +VK + E+SGA + +S+     N  ER++T++G    + KA 
Sbjct: 17  RLLMHGKEVGSIIGKKGESVKKMREESGARINISEG----NCPERIITLAGPTNAIFKAF 72

Query: 194 SAIVQKVQEDPQSSSCLNISYANVAGPVANSNPTGSPYASPADVLPAAAAASAAAASG 251
           + I+ K++ED  SS             + NS     P  +   V+PA+   S     G
Sbjct: 73  AMIIDKLEEDISSS-------------MTNSTAASRPPVTLRLVVPASQCGSLIGKGG 117



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 23/63 (36%), Positives = 38/63 (60%), Gaps = 2/63 (3%)

Query: 401 AAESAKELVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTIT 460
           AA      + + VP +  G+++GKGG  + E +E TGA++Q++  G+ LP +  R +TI 
Sbjct: 92  AASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVA--GDMLPNSTERAITIA 149

Query: 461 GSP 463
           G P
Sbjct: 150 GIP 152



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 19/59 (32%), Positives = 33/59 (55%), Gaps = 2/59 (3%)

Query: 134 KLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKA 192
           +L +PN   G IIG+ GA +  + + SGA ++++   EG    +R VT++G    +  A
Sbjct: 291 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGST--DRQVTITGSAASISLA 347



 Score = 33.5 bits (75), Expect = 0.45
 Identities = 18/64 (28%), Positives = 37/64 (57%), Gaps = 3/64 (4%)

Query: 36  KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNAV 95
           ++ IP+   G IIG+ G  I ++++ +GA IK++   +   G+T+R   + G+A +++  
Sbjct: 291 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE---GSTDRQVTITGSAASISLA 347

Query: 96  HSFI 99
              I
Sbjct: 348 QYLI 351



 Score = 29.6 bits (65), Expect = 6.5
 Identities = 13/27 (48%), Positives = 22/27 (81%)

Query: 418 VGAILGKGGKTLVEYQELTGARIQISK 444
           VG+I+GK G+++ + +E +GARI IS+
Sbjct: 25  VGSIIGKKGESVKKMREESGARINISE 51


>gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens]
          Length = 366

 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 50/165 (30%), Positives = 88/165 (53%), Gaps = 21/165 (12%)

Query: 35  LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNA 94
           +++L+     GSIIGK G+++ ++++E+GA I +S+         ER+  + G   A+  
Sbjct: 16  IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAIFK 70

Query: 95  VHSFIAEKVRE-IPQAMTKPEVVNILQPQTTMNPDRAKQAKLIVPNSTAGLIIGKGGATV 153
             + I +K+ E I  +MT     +  +P  T+        +L+VP S  G +IGKGG  +
Sbjct: 71  AFAMIIDKLEEDISSSMTNSTAAS--RPPVTL--------RLVVPASQCGSLIGKGGCKI 120

Query: 154 KAVMEQSGAWVQLS--QKPEGINLQERVVTVSGEPEQVHKAVSAI 196
           K + E +GA VQ++    P   N  ER +T++G P+ + + V  I
Sbjct: 121 KEIRESTGAQVQVAGDMLP---NSTERAITIAGIPQSIIECVKQI 162



 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 31/78 (39%), Positives = 53/78 (67%), Gaps = 3/78 (3%)

Query: 410 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQAA 469
           E+ +P +L+G I+G+ G  + E ++++GA+I+I+   E   G+ +R+VTITGS A+   A
Sbjct: 292 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE---GSTDRQVTITGSAASISLA 348

Query: 470 QYLISQRVTYEQGVRASN 487
           QYLI+ R++ E G   S+
Sbjct: 349 QYLINVRLSSETGGMGSS 366



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 35/118 (29%), Positives = 57/118 (48%), Gaps = 17/118 (14%)

Query: 134 KLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKAV 193
           +L++     G IIGK G +VK + E+SGA + +S+     N  ER++T++G    + KA 
Sbjct: 17  RLLMHGKEVGSIIGKKGESVKKMREESGARINISEG----NCPERIITLAGPTNAIFKAF 72

Query: 194 SAIVQKVQEDPQSSSCLNISYANVAGPVANSNPTGSPYASPADVLPAAAAASAAAASG 251
           + I+ K++ED  SS             + NS     P  +   V+PA+   S     G
Sbjct: 73  AMIIDKLEEDISSS-------------MTNSTAASRPPVTLRLVVPASQCGSLIGKGG 117



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 23/63 (36%), Positives = 38/63 (60%), Gaps = 2/63 (3%)

Query: 401 AAESAKELVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTIT 460
           AA      + + VP +  G+++GKGG  + E +E TGA++Q++  G+ LP +  R +TI 
Sbjct: 92  AASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVA--GDMLPNSTERAITIA 149

Query: 461 GSP 463
           G P
Sbjct: 150 GIP 152



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 19/59 (32%), Positives = 33/59 (55%), Gaps = 2/59 (3%)

Query: 134 KLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKA 192
           +L +PN   G IIG+ GA +  + + SGA ++++   EG    +R VT++G    +  A
Sbjct: 292 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGST--DRQVTITGSAASISLA 348



 Score = 33.5 bits (75), Expect = 0.45
 Identities = 18/64 (28%), Positives = 37/64 (57%), Gaps = 3/64 (4%)

Query: 36  KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNAV 95
           ++ IP+   G IIG+ G  I ++++ +GA IK++   +   G+T+R   + G+A +++  
Sbjct: 292 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE---GSTDRQVTITGSAASISLA 348

Query: 96  HSFI 99
              I
Sbjct: 349 QYLI 352



 Score = 29.6 bits (65), Expect = 6.5
 Identities = 13/27 (48%), Positives = 22/27 (81%)

Query: 418 VGAILGKGGKTLVEYQELTGARIQISK 444
           VG+I+GK G+++ + +E +GARI IS+
Sbjct: 25  VGSIIGKKGESVKKMREESGARINISE 51


>gi|17402900 far upstream element-binding protein [Homo sapiens]
          Length = 644

 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 67/245 (27%), Positives = 101/245 (41%), Gaps = 28/245 (11%)

Query: 28  GEEGEYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTT-ERVCLVQ 86
           G EG   + V IP +A G +IG+ G+ I ++Q + G  I+         GTT ER+  + 
Sbjct: 274 GNEG---IDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDD----GTTPERIAQIT 326

Query: 87  GTAEALNAVHSFIAEKVREIPQAMTK---PEVVNILQPQTTMN---PDRAKQAKLIVPNS 140
           G  +        I + +R +         P      + Q   N   P   ++   IVP  
Sbjct: 327 GPPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTG 386

Query: 141 TAGLIIGKGGATVKAVMEQSGAWVQLSQK-PEGINLQERVVTVSGEPEQVHKAVSAIVQK 199
             GLIIGKGG T+K++ +QSGA ++L +  P   +   ++ T+ G P+Q+  A   I +K
Sbjct: 387 KTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEK 446

Query: 200 VQEDPQSSSCLNISYANVAGPVANSNPTG--SPYASPADVLPAAAAASAAAASGLLGPAG 257
           +               N  GP     P G   P+  P    P         A    GP G
Sbjct: 447 IG-----------GPVNPLGPPVPHGPHGVPGPHGPPGPPGPGTPMGPYNPAPYNPGPPG 495

Query: 258 LAGVG 262
            A  G
Sbjct: 496 PAPHG 500



 Score = 72.8 bits (177), Expect = 7e-13
 Identities = 53/201 (26%), Positives = 97/201 (48%), Gaps = 25/201 (12%)

Query: 5   APDSRKRPLETPPEVVCTKRSNTGEEGEYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGA 64
           AP +     + PP      RS   EE +      +P    G IIG+GG+ I ++Q+E+G 
Sbjct: 79  APQNDSFGTQLPPMHQQQSRSVMTEEYK------VPDGMVGFIIGRGGEQISRIQQESGC 132

Query: 65  TIKLSKSKDFYPGTTERVCLVQGTAEALNAVHSF---IAEKVREIPQAMTKPEVVNILQP 121
            I+++       G  ER C++ GT E++ +       I EK R  P         N +Q 
Sbjct: 133 KIQIAPDSG---GLPERSCMLTGTPESVQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQ- 188

Query: 122 QTTMNPDRAKQAKLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVT 181
                       ++++P S AGL+IGKGG T+K + E++G  + + Q        ++ + 
Sbjct: 189 ------------EIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLR 236

Query: 182 VSGEPEQVHKAVSAIVQKVQE 202
           ++G+P +V +A   +++ +++
Sbjct: 237 ITGDPYKVQQAKEMVLELIRD 257



 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 45/157 (28%), Positives = 66/157 (42%), Gaps = 50/157 (31%)

Query: 368 AGAGGGAGGGGGPLVA-----------AAAAAGAAGGFLT-------------------- 396
           AG GGG GGGGG   A           AA   G AG  L                     
Sbjct: 15  AGGGGGGGGGGGVNDAFKDALQRARQIAAKIGGDAGTSLNSNDYGYGGQKRPLEDGDQPD 74

Query: 397 AEKLAAES----------------AKELVEIAVPENLVGAILGKGGKTLVEYQELTGARI 440
           A+K+A ++                +    E  VP+ +VG I+G+GG+ +   Q+ +G +I
Sbjct: 75  AKKVAPQNDSFGTQLPPMHQQQSRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKI 134

Query: 441 QISKKGEFLPGTRNRRVTITGSPAATQAAQYLISQRV 477
           QI+     LP    R   +TG+P + Q+A+ L+ Q V
Sbjct: 135 QIAPDSGGLP---ERSCMLTGTPESVQSAKRLLDQIV 168



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 22/75 (29%), Positives = 42/75 (56%), Gaps = 1/75 (1%)

Query: 410 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQAA 469
           EI +P +  G ++GKGG+T+ + QE  G ++ + + G    G  ++ + ITG P   Q A
Sbjct: 189 EIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGA-DKPLRITGDPYKVQQA 247

Query: 470 QYLISQRVTYEQGVR 484
           + ++ + +  + G R
Sbjct: 248 KEMVLELIRDQGGFR 262



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 26/104 (25%), Positives = 43/104 (41%), Gaps = 4/104 (3%)

Query: 374 AGGGGGPLVAAAAAAGAAGGFLTAEKLAAESAKELVEIAVPENLVGAILGKGGKTLVEYQ 433
           AG  GGP           G +     +      +     VP    G I+GKGG+T+    
Sbjct: 348 AGNPGGPGPGGRGRGRGQGNW----NMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSIS 403

Query: 434 ELTGARIQISKKGEFLPGTRNRRVTITGSPAATQAAQYLISQRV 477
           + +GARI++ +          +  TI G+P     A+ LI +++
Sbjct: 404 QQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKI 447



 Score = 37.4 bits (85), Expect = 0.031
 Identities = 24/82 (29%), Positives = 39/82 (47%), Gaps = 6/82 (7%)

Query: 407 ELVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAAT 466
           E +++ +P   VG ++G+ G+ + + Q   G RIQ        P    R   ITG P   
Sbjct: 276 EGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTP---ERIAQITGPPDRC 332

Query: 467 QAAQYLISQRVTYEQGVRASNP 488
           Q A  +I+  +   + V+A NP
Sbjct: 333 QHAAEIITDLL---RSVQAGNP 351


>gi|122937319 even-skipped homeobox 2 [Homo sapiens]
          Length = 476

 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 62/168 (36%), Positives = 77/168 (45%), Gaps = 25/168 (14%)

Query: 230 PYASPADVLPAAAAASAAAASGLLGPAGLAGVGAFPAALPAFSGTDLLAISTALNTLASY 289
           P+        AAAA+ AAAA+       +  +  F A    +S  +LL            
Sbjct: 288 PHVGVTAAAAAAAASGAAAAASSPFATSIRPLDTFRALSHPYSRPELLC----------- 336

Query: 290 GYNTNSLGLGLNSAAASGVLAAVAAGANPAAAAAANLLASYAGEAGAGPAGGAAPPP--- 346
             +    GL    AAA+G+ +A +A A  AAAAAA   AS A  AGA P+GG+AP     
Sbjct: 337 --SFRHPGLYQAPAAAAGLNSAASAAAAAAAAAAA---ASSAAAAGAPPSGGSAPCSCLS 391

Query: 347 -PPPPGALGSFALAAAANGYLGAGAGGGAGGGGGPLVAAAAAAGAAGG 393
                 A  + A AAAA G  G G GGG GGGGG        AGA GG
Sbjct: 392 CHSSQSAAAAAAAAAAALGSRGGGGGGGGGGGGG-----GGGAGAGGG 434



 Score = 31.2 bits (69), Expect = 2.2
 Identities = 39/129 (30%), Positives = 46/129 (35%), Gaps = 12/129 (9%)

Query: 307 GVLAAVAAGANPAAAAAANLLASYAGEAGAGPAGGAAPPPPPPPGALGSF---------A 357
           GV AA AA A   AAAAA+  + +A          A   P   P  L SF         A
Sbjct: 291 GVTAAAAAAAASGAAAAAS--SPFATSIRPLDTFRALSHPYSRPELLCSFRHPGLYQAPA 348

Query: 358 LAAAANGYLGAGAGGGAGGGGGPLVAAAAAAGAAGGFLTAEKLAAESAKELVEIAVPENL 417
            AA  N    A A   A        AAAA A  +GG      L+  S++     A     
Sbjct: 349 AAAGLNSAASAAAAAAAAAAAASS-AAAAGAPPSGGSAPCSCLSCHSSQSAAAAAAAAAA 407

Query: 418 VGAILGKGG 426
                G GG
Sbjct: 408 ALGSRGGGG 416


>gi|145312259 tudor and KH domain containing isoform a [Homo
           sapiens]
          Length = 561

 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 52/180 (28%), Positives = 83/180 (46%), Gaps = 34/180 (18%)

Query: 30  EGEYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQG-- 87
           E +  +++ +P  A   IIG+ G  I QL+K+TGA I +    D      ERV L+ G  
Sbjct: 50  EDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV----DTEDVGDERVLLISGFP 105

Query: 88  --TAEALNAVHSFIAEKVREIPQAMTKPEVVNILQPQTTMNPDRAKQAKLIVPNSTAGLI 145
               +A  A+H  + E      Q                          L VP  + G I
Sbjct: 106 VQVCKAKAAIHQILTENTPVSEQ--------------------------LSVPQRSVGRI 139

Query: 146 IGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKAVSAIVQKVQEDPQ 205
           IG+GG T++++ + SGA +   ++ EG  L  R++ +SG  ++V  A   I++KV ED +
Sbjct: 140 IGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEE 199



 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 31/96 (32%), Positives = 51/96 (53%), Gaps = 3/96 (3%)

Query: 132 QAKLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHK 191
           + ++ VP     LIIG+ GA +K + +Q+GA + +  +  G    ERV+ +SG P QV K
Sbjct: 54  EIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVG---DERVLLISGFPVQVCK 110

Query: 192 AVSAIVQKVQEDPQSSSCLNISYANVAGPVANSNPT 227
           A +AI Q + E+   S  L++   +V   +     T
Sbjct: 111 AKAAIHQILTENTPVSEQLSVPQRSVGRIIGRGGET 146



 Score = 45.8 bits (107), Expect = 9e-05
 Identities = 26/88 (29%), Positives = 53/88 (60%), Gaps = 5/88 (5%)

Query: 399 KLAAESAKELVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGT--RNRR 456
           ++  E+     +++VP+  VG I+G+GG+T+    + +GA+I   K+ E   GT   +R 
Sbjct: 117 QILTENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESE---GTLLLSRL 173

Query: 457 VTITGSPAATQAAQYLISQRVTYEQGVR 484
           + I+G+     AA++LI ++V+ ++ +R
Sbjct: 174 IKISGTQKEVAAAKHLILEKVSEDEELR 201



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 6/84 (7%)

Query: 409 VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQA 468
           +E+ VP+  V  I+G+ G  + + ++ TGARI +  +         R + I+G P     
Sbjct: 55  IEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDV----GDERVLLISGFPVQVCK 110

Query: 469 AQYLISQRVTYEQGV--RASNPQK 490
           A+  I Q +T    V  + S PQ+
Sbjct: 111 AKAAIHQILTENTPVSEQLSVPQR 134


>gi|145312270 tudor and KH domain containing isoform a [Homo
           sapiens]
          Length = 561

 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 52/180 (28%), Positives = 83/180 (46%), Gaps = 34/180 (18%)

Query: 30  EGEYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQG-- 87
           E +  +++ +P  A   IIG+ G  I QL+K+TGA I +    D      ERV L+ G  
Sbjct: 50  EDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV----DTEDVGDERVLLISGFP 105

Query: 88  --TAEALNAVHSFIAEKVREIPQAMTKPEVVNILQPQTTMNPDRAKQAKLIVPNSTAGLI 145
               +A  A+H  + E      Q                          L VP  + G I
Sbjct: 106 VQVCKAKAAIHQILTENTPVSEQ--------------------------LSVPQRSVGRI 139

Query: 146 IGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKAVSAIVQKVQEDPQ 205
           IG+GG T++++ + SGA +   ++ EG  L  R++ +SG  ++V  A   I++KV ED +
Sbjct: 140 IGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEE 199



 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 31/96 (32%), Positives = 51/96 (53%), Gaps = 3/96 (3%)

Query: 132 QAKLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHK 191
           + ++ VP     LIIG+ GA +K + +Q+GA + +  +  G    ERV+ +SG P QV K
Sbjct: 54  EIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVG---DERVLLISGFPVQVCK 110

Query: 192 AVSAIVQKVQEDPQSSSCLNISYANVAGPVANSNPT 227
           A +AI Q + E+   S  L++   +V   +     T
Sbjct: 111 AKAAIHQILTENTPVSEQLSVPQRSVGRIIGRGGET 146



 Score = 45.8 bits (107), Expect = 9e-05
 Identities = 26/88 (29%), Positives = 53/88 (60%), Gaps = 5/88 (5%)

Query: 399 KLAAESAKELVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGT--RNRR 456
           ++  E+     +++VP+  VG I+G+GG+T+    + +GA+I   K+ E   GT   +R 
Sbjct: 117 QILTENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESE---GTLLLSRL 173

Query: 457 VTITGSPAATQAAQYLISQRVTYEQGVR 484
           + I+G+     AA++LI ++V+ ++ +R
Sbjct: 174 IKISGTQKEVAAAKHLILEKVSEDEELR 201



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 6/84 (7%)

Query: 409 VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQA 468
           +E+ VP+  V  I+G+ G  + + ++ TGARI +  +         R + I+G P     
Sbjct: 55  IEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDV----GDERVLLISGFPVQVCK 110

Query: 469 AQYLISQRVTYEQGV--RASNPQK 490
           A+  I Q +T    V  + S PQ+
Sbjct: 111 AKAAIHQILTENTPVSEQLSVPQR 134


>gi|145312256 tudor and KH domain containing isoform a [Homo
           sapiens]
          Length = 561

 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 52/180 (28%), Positives = 83/180 (46%), Gaps = 34/180 (18%)

Query: 30  EGEYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQG-- 87
           E +  +++ +P  A   IIG+ G  I QL+K+TGA I +    D      ERV L+ G  
Sbjct: 50  EDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV----DTEDVGDERVLLISGFP 105

Query: 88  --TAEALNAVHSFIAEKVREIPQAMTKPEVVNILQPQTTMNPDRAKQAKLIVPNSTAGLI 145
               +A  A+H  + E      Q                          L VP  + G I
Sbjct: 106 VQVCKAKAAIHQILTENTPVSEQ--------------------------LSVPQRSVGRI 139

Query: 146 IGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKAVSAIVQKVQEDPQ 205
           IG+GG T++++ + SGA +   ++ EG  L  R++ +SG  ++V  A   I++KV ED +
Sbjct: 140 IGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEE 199



 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 31/96 (32%), Positives = 51/96 (53%), Gaps = 3/96 (3%)

Query: 132 QAKLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHK 191
           + ++ VP     LIIG+ GA +K + +Q+GA + +  +  G    ERV+ +SG P QV K
Sbjct: 54  EIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVG---DERVLLISGFPVQVCK 110

Query: 192 AVSAIVQKVQEDPQSSSCLNISYANVAGPVANSNPT 227
           A +AI Q + E+   S  L++   +V   +     T
Sbjct: 111 AKAAIHQILTENTPVSEQLSVPQRSVGRIIGRGGET 146



 Score = 45.8 bits (107), Expect = 9e-05
 Identities = 26/88 (29%), Positives = 53/88 (60%), Gaps = 5/88 (5%)

Query: 399 KLAAESAKELVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGT--RNRR 456
           ++  E+     +++VP+  VG I+G+GG+T+    + +GA+I   K+ E   GT   +R 
Sbjct: 117 QILTENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESE---GTLLLSRL 173

Query: 457 VTITGSPAATQAAQYLISQRVTYEQGVR 484
           + I+G+     AA++LI ++V+ ++ +R
Sbjct: 174 IKISGTQKEVAAAKHLILEKVSEDEELR 201



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 6/84 (7%)

Query: 409 VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQA 468
           +E+ VP+  V  I+G+ G  + + ++ TGARI +  +         R + I+G P     
Sbjct: 55  IEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDV----GDERVLLISGFPVQVCK 110

Query: 469 AQYLISQRVTYEQGV--RASNPQK 490
           A+  I Q +T    V  + S PQ+
Sbjct: 111 AKAAIHQILTENTPVSEQLSVPQR 134


>gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a
           [Homo sapiens]
          Length = 464

 Score = 70.5 bits (171), Expect = 3e-12
 Identities = 59/207 (28%), Positives = 96/207 (46%), Gaps = 22/207 (10%)

Query: 10  KRPLETPPEVVCTKRS-NTGEEGEYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKL 68
           KRP E   E    KRS NT E  E  L++L+ S  AG++IGKGG+ I  L+ +  A++ +
Sbjct: 21  KRPAEDMEEEQAFKRSRNTDEMVE--LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSV 78

Query: 69  SKSKDFYPGTTERVCLVQGTAEALNAVHSFIAEKVRE---------IPQAMTKPEVVNIL 119
             S        ER+  +    E +  +   I   + E           Q   + + V  L
Sbjct: 79  PDSSG-----PERILSISADIETIGEILKKIIPTLEEGLQLPSPTATSQLPLESDAVECL 133

Query: 120 QPQTTMNPDRAKQAKLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQK--PEGINLQE 177
             Q     D   + +L++  S AG IIG  GA +K + E +   ++L Q+  P      +
Sbjct: 134 NYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHS---TD 190

Query: 178 RVVTVSGEPEQVHKAVSAIVQKVQEDP 204
           RVV + G+P++V + +  I+  + E P
Sbjct: 191 RVVLIGGKPDRVVECIKIILDLISESP 217



 Score = 52.8 bits (125), Expect = 7e-07
 Identities = 34/113 (30%), Positives = 54/113 (47%), Gaps = 28/113 (24%)

Query: 365 YLGAGAGGGAGGGGGPLVAAAAAAGAAGGFLTAEKLAAESAKELVEIAVPENLVGAILGK 424
           Y  AG  G  G  GGP++                           ++ +P++L G+I+GK
Sbjct: 371 YSYAGGRGSYGDLGGPIITT-------------------------QVTIPKDLAGSIIGK 405

Query: 425 GGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQAAQYLISQRV 477
           GG+ + + +  +GA I+I    E L G+ +R +TITG+    Q AQYL+   V
Sbjct: 406 GGQRIKQIRHESGASIKID---EPLEGSEDRIITITGTQDQIQNAQYLLQNSV 455



 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 25/70 (35%), Positives = 42/70 (60%), Gaps = 3/70 (4%)

Query: 36  KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNAV 95
           +V IP   AGSIIGKGGQ I Q++ E+GA+IK+ +  +   G+ +R+  + GT + +   
Sbjct: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLE---GSEDRIITITGTQDQIQNA 447

Query: 96  HSFIAEKVRE 105
              +   V++
Sbjct: 448 QYLLQNSVKQ 457



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 21/69 (30%), Positives = 42/69 (60%), Gaps = 2/69 (2%)

Query: 134 KLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKAV 193
           ++ +P   AG IIGKGG  +K +  +SGA +++ +  EG   ++R++T++G  +Q+  A 
Sbjct: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEG--SEDRIITITGTQDQIQNAQ 448

Query: 194 SAIVQKVQE 202
             +   V++
Sbjct: 449 YLLQNSVKQ 457



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 30/105 (28%), Positives = 50/105 (47%), Gaps = 2/105 (1%)

Query: 3   PEAPDSRKRPLETPPEVVCTKRSNTGEEGEYFLKVLIPSYAAGSIIGKGGQTIVQLQKET 62
           P    + + PLE+        +   G + +  L++LI    AG IIG  G  I +L++ T
Sbjct: 115 PSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENT 174

Query: 63  GATIKLSKSKDFYPGTTERVCLVQGTAEALNAVHSFIAEKVREIP 107
             TIKL   ++  P +T+RV L+ G  + +      I + + E P
Sbjct: 175 QTTIKL--FQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESP 217


>gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b
           [Homo sapiens]
          Length = 463

 Score = 70.5 bits (171), Expect = 3e-12
 Identities = 59/207 (28%), Positives = 96/207 (46%), Gaps = 22/207 (10%)

Query: 10  KRPLETPPEVVCTKRS-NTGEEGEYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKL 68
           KRP E   E    KRS NT E  E  L++L+ S  AG++IGKGG+ I  L+ +  A++ +
Sbjct: 21  KRPAEDMEEEQAFKRSRNTDEMVE--LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSV 78

Query: 69  SKSKDFYPGTTERVCLVQGTAEALNAVHSFIAEKVRE---------IPQAMTKPEVVNIL 119
             S        ER+  +    E +  +   I   + E           Q   + + V  L
Sbjct: 79  PDSSG-----PERILSISADIETIGEILKKIIPTLEEGLQLPSPTATSQLPLESDAVECL 133

Query: 120 QPQTTMNPDRAKQAKLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQK--PEGINLQE 177
             Q     D   + +L++  S AG IIG  GA +K + E +   ++L Q+  P      +
Sbjct: 134 NYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHS---TD 190

Query: 178 RVVTVSGEPEQVHKAVSAIVQKVQEDP 204
           RVV + G+P++V + +  I+  + E P
Sbjct: 191 RVVLIGGKPDRVVECIKIILDLISESP 217



 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 35/118 (29%), Positives = 55/118 (46%), Gaps = 28/118 (23%)

Query: 365 YLGAGAGGGAGGGGGPLVAAAAAAGAAGGFLTAEKLAAESAKELVEIAVPENLVGAILGK 424
           Y  AG  G  G  GGP++                           ++ +P++L G+I+GK
Sbjct: 371 YSYAGGRGSYGDLGGPIITT-------------------------QVTIPKDLAGSIIGK 405

Query: 425 GGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQAAQYLISQRVTYEQG 482
           GG+ + + +  +GA I+I    E L G+ +R +TITG+    Q AQYL+   V    G
Sbjct: 406 GGQRIKQIRHESGASIKID---EPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQYSG 460



 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 25/70 (35%), Positives = 42/70 (60%), Gaps = 3/70 (4%)

Query: 36  KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNAV 95
           +V IP   AGSIIGKGGQ I Q++ E+GA+IK+ +  +   G+ +R+  + GT + +   
Sbjct: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLE---GSEDRIITITGTQDQIQNA 447

Query: 96  HSFIAEKVRE 105
              +   V++
Sbjct: 448 QYLLQNSVKQ 457



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 21/69 (30%), Positives = 42/69 (60%), Gaps = 2/69 (2%)

Query: 134 KLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKAV 193
           ++ +P   AG IIGKGG  +K +  +SGA +++ +  EG   ++R++T++G  +Q+  A 
Sbjct: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEG--SEDRIITITGTQDQIQNAQ 448

Query: 194 SAIVQKVQE 202
             +   V++
Sbjct: 449 YLLQNSVKQ 457



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 30/105 (28%), Positives = 50/105 (47%), Gaps = 2/105 (1%)

Query: 3   PEAPDSRKRPLETPPEVVCTKRSNTGEEGEYFLKVLIPSYAAGSIIGKGGQTIVQLQKET 62
           P    + + PLE+        +   G + +  L++LI    AG IIG  G  I +L++ T
Sbjct: 115 PSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENT 174

Query: 63  GATIKLSKSKDFYPGTTERVCLVQGTAEALNAVHSFIAEKVREIP 107
             TIKL   ++  P +T+RV L+ G  + +      I + + E P
Sbjct: 175 QTTIKL--FQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESP 217


>gi|14165437 heterogeneous nuclear ribonucleoprotein K isoform a
           [Homo sapiens]
          Length = 464

 Score = 70.5 bits (171), Expect = 3e-12
 Identities = 59/207 (28%), Positives = 96/207 (46%), Gaps = 22/207 (10%)

Query: 10  KRPLETPPEVVCTKRS-NTGEEGEYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKL 68
           KRP E   E    KRS NT E  E  L++L+ S  AG++IGKGG+ I  L+ +  A++ +
Sbjct: 21  KRPAEDMEEEQAFKRSRNTDEMVE--LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSV 78

Query: 69  SKSKDFYPGTTERVCLVQGTAEALNAVHSFIAEKVRE---------IPQAMTKPEVVNIL 119
             S        ER+  +    E +  +   I   + E           Q   + + V  L
Sbjct: 79  PDSSG-----PERILSISADIETIGEILKKIIPTLEEGLQLPSPTATSQLPLESDAVECL 133

Query: 120 QPQTTMNPDRAKQAKLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQK--PEGINLQE 177
             Q     D   + +L++  S AG IIG  GA +K + E +   ++L Q+  P      +
Sbjct: 134 NYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHS---TD 190

Query: 178 RVVTVSGEPEQVHKAVSAIVQKVQEDP 204
           RVV + G+P++V + +  I+  + E P
Sbjct: 191 RVVLIGGKPDRVVECIKIILDLISESP 217



 Score = 52.8 bits (125), Expect = 7e-07
 Identities = 34/113 (30%), Positives = 54/113 (47%), Gaps = 28/113 (24%)

Query: 365 YLGAGAGGGAGGGGGPLVAAAAAAGAAGGFLTAEKLAAESAKELVEIAVPENLVGAILGK 424
           Y  AG  G  G  GGP++                           ++ +P++L G+I+GK
Sbjct: 371 YSYAGGRGSYGDLGGPIITT-------------------------QVTIPKDLAGSIIGK 405

Query: 425 GGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQAAQYLISQRV 477
           GG+ + + +  +GA I+I    E L G+ +R +TITG+    Q AQYL+   V
Sbjct: 406 GGQRIKQIRHESGASIKID---EPLEGSEDRIITITGTQDQIQNAQYLLQNSV 455



 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 25/70 (35%), Positives = 42/70 (60%), Gaps = 3/70 (4%)

Query: 36  KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNAV 95
           +V IP   AGSIIGKGGQ I Q++ E+GA+IK+ +  +   G+ +R+  + GT + +   
Sbjct: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLE---GSEDRIITITGTQDQIQNA 447

Query: 96  HSFIAEKVRE 105
              +   V++
Sbjct: 448 QYLLQNSVKQ 457



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 21/69 (30%), Positives = 42/69 (60%), Gaps = 2/69 (2%)

Query: 134 KLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKAV 193
           ++ +P   AG IIGKGG  +K +  +SGA +++ +  EG   ++R++T++G  +Q+  A 
Sbjct: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEG--SEDRIITITGTQDQIQNAQ 448

Query: 194 SAIVQKVQE 202
             +   V++
Sbjct: 449 YLLQNSVKQ 457



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 30/105 (28%), Positives = 50/105 (47%), Gaps = 2/105 (1%)

Query: 3   PEAPDSRKRPLETPPEVVCTKRSNTGEEGEYFLKVLIPSYAAGSIIGKGGQTIVQLQKET 62
           P    + + PLE+        +   G + +  L++LI    AG IIG  G  I +L++ T
Sbjct: 115 PSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENT 174

Query: 63  GATIKLSKSKDFYPGTTERVCLVQGTAEALNAVHSFIAEKVREIP 107
             TIKL   ++  P +T+RV L+ G  + +      I + + E P
Sbjct: 175 QTTIKL--FQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESP 217


>gi|100816392 far upstream element (FUSE) binding protein 3 [Homo
           sapiens]
          Length = 572

 Score = 69.3 bits (168), Expect = 7e-12
 Identities = 41/168 (24%), Positives = 86/168 (51%), Gaps = 13/168 (7%)

Query: 39  IPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNAVHSF 98
           +P    G IIG+GG+ I ++Q E+G  I+++       G  ER C++ GT E++      
Sbjct: 84  VPDKMVGFIIGRGGEQISRIQAESGCKIQIASESS---GIPERPCVLTGTPESIEQAKRL 140

Query: 99  IAEKVREIPQAMTKPEVVNILQPQTTMNPDRAKQAKLIVPNSTAGLIIGKGGATVKAVME 158
           + + V    +    P   N +   +T+        ++++P S  GL+IG+GG T+K + E
Sbjct: 141 LGQIV---DRCRNGPGFHNDIDSNSTIQ-------EILIPASKVGLVIGRGGETIKQLQE 190

Query: 159 QSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKAVSAIVQKVQEDPQS 206
           ++G  + + Q        ++ + ++G+  +V +A   +++ ++E  Q+
Sbjct: 191 RTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQA 238



 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 58/236 (24%), Positives = 95/236 (40%), Gaps = 47/236 (19%)

Query: 35  LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNA 94
           ++V +P +A G +IG+ G+ I ++Q + G  I+        P   ER   V G  +    
Sbjct: 256 IEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISP---ERAAQVMGPPDRCQH 312

Query: 95  VHSFIAEKVREIPQAMTKPEVVNILQPQ---------TTMNPDRAKQAKLIVPNSTAGLI 145
               I+E +     A  +     +   +         +   P   ++    VP    GL+
Sbjct: 313 AAHIISELILT---AQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYTVPADKCGLV 369

Query: 146 IGKGGATVKAVMEQSGAWVQLSQK-PEGINLQERVVTVSGEPEQVHKAVSAIVQKV---- 200
           IGKGG  +K++ +QSGA V+L +  P   +   R  T+ G P+Q+  A   I +KV    
Sbjct: 370 IGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVARQLIDEKVGGTN 429

Query: 201 ----------------------QEDPQSSSCLNISYANVAGPVANSNPTGSPYASP 234
                                    P+SS C    + N+A  V N NP  +P + P
Sbjct: 430 LGAPGAFGQSPFSQPPAPPHQNTFPPRSSGC----FPNMAAKV-NGNPHSTPVSGP 480



 Score = 60.1 bits (144), Expect = 5e-09
 Identities = 58/246 (23%), Positives = 101/246 (41%), Gaps = 24/246 (9%)

Query: 3   PEAPDSRKRPLETPPEVVCTKRSNTG-----EEGEYFLKVLIPSYAAGSIIGKGGQTIVQ 57
           PE+ +  KR L    ++V   R+  G     +      ++LIP+   G +IG+GG+TI Q
Sbjct: 131 PESIEQAKRLLG---QIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQ 187

Query: 58  LQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNAVHSFIAEKVREIPQAMTKPEVVN 117
           LQ+ TG  + + +     P   ++   + G A  +      + E +RE  QA  +    +
Sbjct: 188 LQERTGVKMVMIQDGPL-PTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVRGD 246

Query: 118 ILQPQTTMNPDRAKQAKLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQE 177
                + M        ++ VP    G++IG+ G  +K +   +G  +Q   KP+     E
Sbjct: 247 F---NSRMG---GGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQF--KPDDGISPE 298

Query: 178 RVVTVSGEPEQVHKAVSAIVQKVQEDPQSSSCLNISYANVAGPVANSNPTGSP------- 230
           R   V G P++   A   I + +    +      ++ A   G        G+P       
Sbjct: 299 RAAQVMGPPDRCQHAAHIISELILTAQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEIT 358

Query: 231 YASPAD 236
           Y  PAD
Sbjct: 359 YTVPAD 364



 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 76/373 (20%), Positives = 128/373 (34%), Gaps = 63/373 (16%)

Query: 137 VPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKA---V 193
           VP+   G IIG+GG  +  +  +SG  +Q++ +  GI   ER   ++G PE + +A   +
Sbjct: 84  VPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGI--PERPCVLTGTPESIEQAKRLL 141

Query: 194 SAIVQKVQEDPQSSSCLNISYANVAGPVANSNPTGSPYASPADVLPAAAAASAAAASGLL 253
             IV + +  P   + ++            SN T      PA  +             L 
Sbjct: 142 GQIVDRCRNGPGFHNDID------------SNSTIQEILIPASKVGLVIGRGGETIKQLQ 189

Query: 254 GPAGLAGVGAFPAALPAFSGTDLLAISTALNTLASY-------------------GYNTN 294
              G+  V      LP  +   L     A     +                    G   +
Sbjct: 190 ERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVRGDFNS 249

Query: 295 SLGLGLNSAAASGVLAAVAAGANPAAAAA----ANLLASYAGEAGAGPAGGAAPPPPPPP 350
            +G G    +       +  G N          A +   +  + G  P   A    PP  
Sbjct: 250 RMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDR 309

Query: 351 GALGSFAL------AAAANGYLGAGAGGGAGGGGGPLVAAAAAAGAAGGFLTAEKLAAES 404
               +  +      A   +G+ G  A  G G G G       + GA GG           
Sbjct: 310 CQHAAHIISELILTAQERDGFGGLAAARGRGRGRGDW-----SVGAPGGV---------- 354

Query: 405 AKELVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPA 464
             + +   VP +  G ++GKGG+ +    + +GA +++ +          RR TI G P 
Sbjct: 355 --QEITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQ 412

Query: 465 ATQAAQYLISQRV 477
             + A+ LI ++V
Sbjct: 413 QIEVARQLIDEKV 425



 Score = 45.8 bits (107), Expect = 9e-05
 Identities = 23/68 (33%), Positives = 40/68 (58%), Gaps = 3/68 (4%)

Query: 410 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQAA 469
           E  VP+ +VG I+G+GG+ +   Q  +G +IQI+ +   +P    R   +TG+P + + A
Sbjct: 81  EFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIP---ERPCVLTGTPESIEQA 137

Query: 470 QYLISQRV 477
           + L+ Q V
Sbjct: 138 KRLLGQIV 145



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 26/95 (27%), Positives = 52/95 (54%), Gaps = 6/95 (6%)

Query: 403 ESAKELVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGS 462
           +S   + EI +P + VG ++G+GG+T+ + QE TG ++ + + G  LP   ++ + ITG 
Sbjct: 159 DSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGP-LPTGADKPLRITGD 217

Query: 463 PAATQAAQYLISQRVTYE-----QGVRASNPQKVG 492
               Q A+ ++ + +  +     +GVR     ++G
Sbjct: 218 AFKVQQAREMVLEIIREKDQADFRGVRGDFNSRMG 252



 Score = 38.9 bits (89), Expect = 0.011
 Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 3/73 (4%)

Query: 409 VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQA 468
           +E++VP   VG ++G+ G+ + + Q   G RIQ        P    R   + G P   Q 
Sbjct: 256 IEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISP---ERAAQVMGPPDRCQH 312

Query: 469 AQYLISQRVTYEQ 481
           A ++IS+ +   Q
Sbjct: 313 AAHIISELILTAQ 325


>gi|64085377 insulin-like growth factor 2 mRNA binding protein 2
           isoform a [Homo sapiens]
          Length = 599

 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 51/174 (29%), Positives = 86/174 (49%), Gaps = 19/174 (10%)

Query: 35  LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNA 94
           + + IP+ A G+IIGK G  I QL +  GA+IK++ ++   P  +ER+ ++ G  EA   
Sbjct: 430 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEG--PDVSERMVIITGPPEAQFK 487

Query: 95  VHSFIAEKVREIPQAMTKPEVVNILQPQTTMNPDRAKQAKLIVPNSTAGLIIGKGGATVK 154
               I  K++E           N   P+  +      +A + VP+STAG +IGKGG TV 
Sbjct: 488 AQGRIFGKLKE----------ENFFNPKEEVK----LEAHIRVPSSTAGRVIGKGGKTVN 533

Query: 155 AVMEQSGAWVQLSQKPEGINLQERVVTVSGE---PEQVHKAVSAIVQKVQEDPQ 205
            +   + A V + +       +E +V + G     +   + +  IVQ+V++  Q
Sbjct: 534 ELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQ 587



 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 56/220 (25%), Positives = 96/220 (43%), Gaps = 28/220 (12%)

Query: 32  EYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEA 91
           ++ L++L+P+   G+IIGK G TI  + K+T + + + + ++   G  E+   +  T E 
Sbjct: 193 DFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKEN--SGAAEKPVTIHATPEG 250

Query: 92  LNAVHSFIAEKVREIPQAMTKPEVVNILQPQTTMNPDRAKQAKLIVPNSTAGLIIGKGGA 151
                   +E  R I + M K      L  +  +        K++  N   G +IGK G 
Sbjct: 251 -------TSEACRMILEIMQKEADETKLAEEIPL--------KILAHNGLVGRLIGKEGR 295

Query: 152 TVKAVMEQSGAWVQLSQKPE-GINLQERVVTVSGEPEQVHKAVSAIVQKVQEDPQSSSCL 210
            +K +  ++G  + +S   +  I   ER +TV G  E    A   I++K++E  ++    
Sbjct: 296 NLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLA 355

Query: 211 NISYANVAGPVANSNPTG---------SPYASPADVLPAA 241
               AN+  P  N +  G         SP A P    PAA
Sbjct: 356 VNQQANLI-PGLNLSALGIFSTGLSVLSPPAGPRGAPPAA 394



 Score = 56.6 bits (135), Expect = 5e-08
 Identities = 94/405 (23%), Positives = 148/405 (36%), Gaps = 55/405 (13%)

Query: 134 KLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKAV 193
           +++VP    G IIGK G T+K + +Q+ + V + +K E     E+ VT+   PE   +A 
Sbjct: 197 RILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRK-ENSGAAEKPVTIHATPEGTSEAC 255

Query: 194 SAIVQKVQEDPQSSSCLN------ISYANVAGPVANS---------NPTGSPYA-SPADV 237
             I++ +Q++   +          +++  + G +            + TG+    S    
Sbjct: 256 RMILEIMQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQD 315

Query: 238 LPAAAAASAAAASGLLGPAGLAGVGAFPAALPAFSGTDLLAISTALNTLASYGYNTNSLG 297
           L            G +     A +        AF   D+LA++   N +   G N ++LG
Sbjct: 316 LSIYNPERTITVKGTVEACASAEIEIMKKLREAFEN-DMLAVNQQANLIP--GLNLSALG 372

Query: 298 LGLNSAAASGVLAAVAAGANPAAAAAANLLASYAGE-AGAGPAGGAAPPPP----PPPGA 352
           +    +    VL+  A       AA  +   +++G  +   P     P P     P    
Sbjct: 373 I---FSTGLSVLSPPAGPRGAPPAAPYHPFTTHSGYFSSLYPHHQFGPFPHHHSYPEQEI 429

Query: 353 LGSFALAAAANGYLG------------AGAGGGAGGGGGPLV------------AAAAAA 388
           +  F    A    +G            AGA        GP V            A   A 
Sbjct: 430 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 489

Query: 389 GAAGGFLTAEKL--AAESAKELVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKG 446
           G   G L  E      E  K    I VP +  G ++GKGGKT+ E Q LT A + I  + 
Sbjct: 490 GRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEV-IVPRD 548

Query: 447 EFLPGTRNRRVTITGSPAATQAAQYLISQRVTYEQGVRASNPQKV 491
           +         V I G   A+Q AQ  I + V   +      PQ V
Sbjct: 549 QTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQKYPQGV 593



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 28/88 (31%), Positives = 45/88 (51%)

Query: 18  EVVCTKRSNTGEEGEYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPG 77
           E++  +   T    E  LK+L  +   G +IGK G+ + +++ ETG  I +S  +D    
Sbjct: 260 EIMQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIY 319

Query: 78  TTERVCLVQGTAEALNAVHSFIAEKVRE 105
             ER   V+GT EA  +    I +K+RE
Sbjct: 320 NPERTITVKGTVEACASAEIEIMKKLRE 347



 Score = 38.5 bits (88), Expect = 0.014
 Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 3/88 (3%)

Query: 26  NTGEEGEYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCL- 84
           N  EE +    + +PS  AG +IGKGG+T+ +LQ  T A + +   +D  P   E V + 
Sbjct: 503 NPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIV--PRDQTPDENEEVIVR 560

Query: 85  VQGTAEALNAVHSFIAEKVREIPQAMTK 112
           + G   A       I E V+++ Q   K
Sbjct: 561 IIGHFFASQTAQRKIREIVQQVKQQEQK 588



 Score = 38.1 bits (87), Expect = 0.018
 Identities = 23/65 (35%), Positives = 33/65 (50%), Gaps = 2/65 (3%)

Query: 409 VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQA 468
           + I VP   VGAI+GK G T+    + T +R+ I +K     G   + VTI  +P  T  
Sbjct: 196 LRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKEN--SGAAEKPVTIHATPEGTSE 253

Query: 469 AQYLI 473
           A  +I
Sbjct: 254 ACRMI 258


>gi|154355000 KH-type splicing regulatory protein [Homo sapiens]
          Length = 711

 Score = 66.2 bits (160), Expect = 6e-11
 Identities = 109/481 (22%), Positives = 177/481 (36%), Gaps = 128/481 (26%)

Query: 8   SRKRPLETPPEVVCTKRSNTGEEGEYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIK 67
           S+  P+  PP    T+        EY     +P    G IIG+GG+ I ++Q+++G  ++
Sbjct: 132 SQLGPIHPPPRTSMTE--------EY----RVPDGMVGLIIGRGGEQINKIQQDSGCKVQ 179

Query: 68  LSKSKDFYPGTTERVCLVQGTAEALNAVHSFIAEKV---REIPQAMTKPEVVNILQPQTT 124
           +S       G  ER   + G  E++      + + V   R  P         N  Q  T 
Sbjct: 180 ISPDSG---GLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNA-NGGQNGTV 235

Query: 125 MNPDRAKQAKLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSG 184
                    ++++P   AGL+IGKGG T+K + E++G  + L Q        ++ + + G
Sbjct: 236 Q--------EIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIG 287

Query: 185 EPEQVHKAVSAIVQKVQEDPQSSSCLNISYANVAGPVANSNPTGSPYASPADVLPAAAAA 244
           +P +V +A   ++  ++E  Q             G   + N  GS      DV       
Sbjct: 288 DPYKVQQACEMVMDILRERDQ-------------GGFGDRNEYGSRIGGGIDV------- 327

Query: 245 SAAAASGLLGPAGLAGVGAFPAALPAFSGTDLLAISTALNTLASYGYNTNSLGLGLNSAA 304
                     P     VG     +   SG  +  I              N  G+ +    
Sbjct: 328 ----------PVPRHSVG----VVIGRSGEMIKKIQ-------------NDAGVRIQFKQ 360

Query: 305 ASGV---LAAVAAGANPAAAAAANLLASYAGEAGAGPAGGAAPP--PPPPPGALGSFALA 359
             G      A   G       AA ++        +GP G   PP  P  PPG        
Sbjct: 361 DDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPG---PPGGPGMPPG-------- 409

Query: 360 AAANGYLGAGAGGGAGGGGGPLVAAAAAAGAAGGFLTAEKLAAESAKELVEIAVPENLVG 419
                  G G G G G  G P           GG +T               ++P +  G
Sbjct: 410 -------GRGRGRGQGNWGPP-----------GGEMT--------------FSIPTHKCG 437

Query: 420 AILGKGGKTLVEYQELTGARIQISKKGEFLP--GTRNRRV-TITGSPAATQAAQYLISQR 476
            ++G+GG+ +    + TGA ++IS++   LP  G  N ++  I GSP     A+ LI ++
Sbjct: 438 LVIGRGGENVKAINQQTGAFVEISRQ---LPPNGDPNFKLFIIRGSPQQIDHAKQLIEEK 494

Query: 477 V 477
           +
Sbjct: 495 I 495



 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 52/213 (24%), Positives = 92/213 (43%), Gaps = 18/213 (8%)

Query: 35  LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNA 94
           + V +P ++ G +IG+ G+ I ++Q + G  I+  +     P   E++  + G  +    
Sbjct: 325 IDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGP---EKIAHIMGPPDRCEH 381

Query: 95  VHSFIAEKVREIPQAMTKPEVVNILQP--------QTTMNPDRAKQAKLIVPNSTAGLII 146
               I + ++ +      P     + P        Q    P   +     +P    GL+I
Sbjct: 382 AARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMT-FSIPTHKCGLVI 440

Query: 147 GKGGATVKAVMEQSGAWVQLS-QKPEGINLQERVVTVSGEPEQVHKAVSAIVQKVQEDPQ 205
           G+GG  VKA+ +Q+GA+V++S Q P   +   ++  + G P+Q+  A   I +K+ E P 
Sbjct: 441 GRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKI-EGPL 499

Query: 206 SSSCLNISYANVAGPVANSNP----TGSPYASP 234
                       AGP+   NP     G P A P
Sbjct: 500 CPVGPGPGGPGPAGPMGPFNPGPFNQGPPGAPP 532



 Score = 62.4 bits (150), Expect = 9e-10
 Identities = 57/205 (27%), Positives = 83/205 (40%), Gaps = 60/205 (29%)

Query: 332 GEAGAGPAGGAAPPPPPPPGALGSFALAAAANGYLGAGAGGGAG---GGGGPLVAAAAAA 388
           G  GAG AGG   PPP PPGA G         G  G G+ GG     GGGGP +   A A
Sbjct: 19  GGGGAGGAGGG--PPPGPPGA-GDRGGGGPGGGGPGGGSAGGPSQPPGGGGPGIRKDAFA 75

Query: 389 GAA------------------------------------GGFLTAEKLAAES-------- 404
            A                                     G    ++KLA++         
Sbjct: 76  DAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPESKKLASQGDSISSQLG 135

Query: 405 -------AKELVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRV 457
                       E  VP+ +VG I+G+GG+ + + Q+ +G ++QIS     LP    R V
Sbjct: 136 PIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLP---ERSV 192

Query: 458 TITGSPAATQAAQYLISQRVTYEQG 482
           ++TG+P + Q A+ ++   V+  +G
Sbjct: 193 SLTGAPESVQKAKMMLDDIVSRGRG 217



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 26/57 (45%), Positives = 27/57 (47%), Gaps = 10/57 (17%)

Query: 341 GAAPPPPPPPGALGSFALAAAAN---GYLGAG-AGGGAGGGGGPLVAAAAAAGAAGG 393
           G  PP PPPP   G  A  A      G  GAG  GGG  GGGGP        G+AGG
Sbjct: 7   GGPPPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGP------GGGSAGG 57



 Score = 32.7 bits (73), Expect = 0.77
 Identities = 22/85 (25%), Positives = 41/85 (48%), Gaps = 8/85 (9%)

Query: 409 VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVT-ITGSPAATQ 467
           +++ VP + VG ++G+ G+ + + Q   G RIQ  +      GT   ++  I G P   +
Sbjct: 325 IDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQD----DGTGPEKIAHIMGPPDRCE 380

Query: 468 AAQYLISQRVTYEQGVRASNPQKVG 492
            A  +I+  +   Q +R+  P   G
Sbjct: 381 HAARIINDLL---QSLRSGPPGPPG 402


>gi|30795212 insulin-like growth factor 2 mRNA binding protein 3
           [Homo sapiens]
          Length = 579

 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 51/200 (25%), Positives = 87/200 (43%), Gaps = 19/200 (9%)

Query: 12  PLETPPEVVCTKRSNTGEEGEYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKS 71
           P   PP  +        +     + + IP+ + G+IIGK GQ I QL +  GA+IK++ +
Sbjct: 385 PTSGPPSAMTPPYPQFEQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPA 444

Query: 72  KDFYPGTTERVCLVQGTAEALNAVHSFIAEKVREIPQAMTKPEVVNILQPQTTMNPDRAK 131
           +   P    R+ ++ G  EA       I  K++E      K EV                
Sbjct: 445 E--APDAKVRMVIITGPPEAQFKAQGRIYGKIKEENFVSPKEEV--------------KL 488

Query: 132 QAKLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGE---PEQ 188
           +A + VP+  AG +IGKGG TV  +   S A V + +        + VV ++G     + 
Sbjct: 489 EAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQVVVKITGHFYACQV 548

Query: 189 VHKAVSAIVQKVQEDPQSSS 208
             + +  I+ +V++  Q  +
Sbjct: 549 AQRKIQEILTQVKQHQQQKA 568



 Score = 59.7 bits (143), Expect = 6e-09
 Identities = 44/169 (26%), Positives = 80/169 (47%), Gaps = 18/169 (10%)

Query: 35  LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNA 94
           L++L+P+   G+IIGK G TI  + K+T + I + + ++   G  E+   +  T E  +A
Sbjct: 198 LRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKEN--AGAAEKSITILSTPEGTSA 255

Query: 95  VHSFIAEKVREIPQAMTKPEVVNILQPQTTMNPDRAKQAKLIVPNSTAGLIIGKGGATVK 154
               I E + +  Q +   E + +               K++  N+  G +IGK G  +K
Sbjct: 256 ACKSILEIMHKEAQDIKFTEEIPL---------------KILAHNNFVGRLIGKEGRNLK 300

Query: 155 AVMEQSGAWVQLSQKPE-GINLQERVVTVSGEPEQVHKAVSAIVQKVQE 202
            + + +   + +S   E  +   ER +TV G  E   KA   I++K++E
Sbjct: 301 KIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRE 349



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 34/103 (33%), Positives = 48/103 (46%), Gaps = 5/103 (4%)

Query: 379 GPLVAAAAAAGAAGGFLTAEKLAA--ESAKELVEIAVPENLVGAILGKGGKTLVEYQELT 436
           GP  A   A G   G +  E   +  E  K    I VP    G ++GKGGKT+ E Q L+
Sbjct: 458 GPPEAQFKAQGRIYGKIKEENFVSPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLS 517

Query: 437 GARIQISKKGEFLPGTRNRRVT-ITGSPAATQAAQYLISQRVT 478
            A + + +  +  P   ++ V  ITG   A Q AQ  I + +T
Sbjct: 518 SAEVVVPR--DQTPDENDQVVVKITGHFYACQVAQRKIQEILT 558



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 29/89 (32%), Positives = 42/89 (47%), Gaps = 2/89 (2%)

Query: 403 ESAKELVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGS 462
           +S  E V + +P   VGAI+GK G+ + +     GA I+I+      P  + R V ITG 
Sbjct: 402 QSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAE--APDAKVRMVIITGP 459

Query: 463 PAATQAAQYLISQRVTYEQGVRASNPQKV 491
           P A   AQ  I  ++  E  V      K+
Sbjct: 460 PEAQFKAQGRIYGKIKEENFVSPKEEVKL 488



 Score = 38.5 bits (88), Expect = 0.014
 Identities = 32/120 (26%), Positives = 56/120 (46%), Gaps = 17/120 (14%)

Query: 4   EAPDSRKRP--LETPPEVVCTKRS------------NTGEEGEYFLKVLIPSYAAGSIIG 49
           EAPD++ R   +  PPE     +             +  EE +    + +PS+AAG +IG
Sbjct: 445 EAPDAKVRMVIITGPPEAQFKAQGRIYGKIKEENFVSPKEEVKLEAHIRVPSFAAGRVIG 504

Query: 50  KGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCL-VQGTAEALNAVHSFIAEKVREIPQ 108
           KGG+T+ +LQ  + A + +   +D  P   ++V + + G   A       I E + ++ Q
Sbjct: 505 KGGKTVNELQNLSSAEVVV--PRDQTPDENDQVVVKITGHFYACQVAQRKIQEILTQVKQ 562



 Score = 38.1 bits (87), Expect = 0.018
 Identities = 20/61 (32%), Positives = 32/61 (52%), Gaps = 2/61 (3%)

Query: 409 VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQA 468
           + + VP   VGAI+GK G T+    + T ++I + +K     G   + +TI  +P  T A
Sbjct: 198 LRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKEN--AGAAEKSITILSTPEGTSA 255

Query: 469 A 469
           A
Sbjct: 256 A 256



 Score = 36.6 bits (83), Expect = 0.053
 Identities = 22/83 (26%), Positives = 41/83 (49%), Gaps = 2/83 (2%)

Query: 409 VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQA 468
           ++I    N VG ++GK G+ L + ++ T  +I IS   E       R +T+ G+      
Sbjct: 279 LKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAK 338

Query: 469 AQYLISQRV--TYEQGVRASNPQ 489
           A+  I +++  +YE  + + N Q
Sbjct: 339 AEEEIMKKIRESYENDIASMNLQ 361


>gi|73427806 v-maf musculoaponeurotic fibrosarcoma oncogene homolog
           isoform b [Homo sapiens]
          Length = 373

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 72/247 (29%), Positives = 104/247 (42%), Gaps = 43/247 (17%)

Query: 198 QKVQEDPQSSSCLNISYANVAGPVANSNPTGSPYASPADVLPAAAAASAAAASGLLGPAG 257
           + V+ D   S C  +    +AG   +S P  +P +S   V P+ + ++ +  SG    A 
Sbjct: 35  EPVETDRIISQCGRL----IAGGSLSSTPMSTPCSS---VPPSPSFSAPSPGSGSEQKAH 87

Query: 258 LAG---VGAFPAALP----AFSGTDLLAISTALNTLASYGYNTNSLGLGLNSAAASGVLA 310
           L     +  +P  L      FS  D +    + +     G++  + G    +AAA     
Sbjct: 88  LEDYYWMTGYPQQLNPEALGFSPEDAVEALISNSHQLQGGFDGYARGAQQLAAAAGAGAG 147

Query: 311 AVAAGAN----PAAAAAANLLASYAGEAGAGP---------AGGAAPPPPPPPGALGSFA 357
           A   G+     PAAA  + ++A+ A ++GAGP         AG    P    PGA GS A
Sbjct: 148 ASLGGSGEEMGPAAAVVSAVIAAAAAQSGAGPHYHHHHHHAAGHHHHPTAGAPGAAGSAA 207

Query: 358 LAAAANGYLGAGA-----GGGAGGGGGPLVAAAAAAG------AAGGF-----LTAEKLA 401
            +A   G  G G      GGG GGGGG    AA A G      AAGG       + E+L 
Sbjct: 208 ASAGGAGGAGGGGPASAGGGGGGGGGGGGGGAAGAGGALHPHHAAGGLHFDDRFSDEQLV 267

Query: 402 AESAKEL 408
             S +EL
Sbjct: 268 TMSVREL 274


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.128    0.355 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,024,631
Number of Sequences: 37866
Number of extensions: 1173801
Number of successful extensions: 26005
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 514
Number of HSP's successfully gapped in prelim test: 716
Number of HSP's that attempted gapping in prelim test: 13240
Number of HSP's gapped (non-prelim): 7357
length of query: 492
length of database: 18,247,518
effective HSP length: 106
effective length of query: 386
effective length of database: 14,233,722
effective search space: 5494216692
effective search space used: 5494216692
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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