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Search of human proteins with 5901948
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5901948 FAS-associated factor 1 [Homo sapiens]
(650 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5901948 FAS-associated factor 1 [Homo sapiens] 1291 0.0
gi|24797106 UBX domain containing 8 [Homo sapiens] 127 2e-29
gi|5031651 reproduction 8 [Homo sapiens] 59 2e-08
gi|24307965 UBX domain containing 2 [Homo sapiens] 57 7e-08
gi|149944496 UBX domain containing 7 [Homo sapiens] 57 7e-08
gi|21361517 UBX domain protein 1 [Homo sapiens] 54 6e-07
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 52 2e-06
gi|56549694 enabled homolog isoform a [Homo sapiens] 50 5e-06
gi|39930375 enabled homolog isoform b [Homo sapiens] 50 5e-06
gi|148746195 trichohyalin [Homo sapiens] 49 2e-05
gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ... 48 2e-05
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 47 4e-05
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 47 4e-05
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 47 4e-05
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 47 4e-05
gi|62244004 modulator of estrogen induced transcription isoform ... 44 4e-04
gi|63176611 modulator of estrogen induced transcription isoform ... 44 4e-04
gi|13376854 UBX domain protein 6 [Homo sapiens] 44 6e-04
gi|4557543 extracellular matrix protein 2 precursor [Homo sapiens] 44 6e-04
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 43 0.001
gi|92859701 myosin VI [Homo sapiens] 43 0.001
gi|147903302 MAP7 domain containing 3 [Homo sapiens] 42 0.001
gi|22035606 mitogen-activated protein kinase kinase kinase kinas... 42 0.002
gi|22035602 mitogen-activated protein kinase kinase kinase kinas... 42 0.002
gi|22758136 MAP7 domain containing 2 [Homo sapiens] 42 0.002
gi|4505101 microtubule-associated protein 7 [Homo sapiens] 42 0.002
gi|15826852 acyl-Coenzyme A binding domain containing 3 [Homo sa... 41 0.003
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 41 0.004
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 41 0.004
gi|27734911 DAZ interacting protein 1-like [Homo sapiens] 41 0.004
>gi|5901948 FAS-associated factor 1 [Homo sapiens]
Length = 650
Score = 1291 bits (3342), Expect = 0.0
Identities = 650/650 (100%), Positives = 650/650 (100%)
Query: 1 MASNMDREMILADFQACTGIENIDEAITLLEQNNWDLVAAINGVIPQENGILQSEYGGET 60
MASNMDREMILADFQACTGIENIDEAITLLEQNNWDLVAAINGVIPQENGILQSEYGGET
Sbjct: 1 MASNMDREMILADFQACTGIENIDEAITLLEQNNWDLVAAINGVIPQENGILQSEYGGET 60
Query: 61 IPGPAFNPASHPASAPTSSSSSAFRPVMPSRQIVERQPRMLDFRVEYRDRNVDVVLEDTC 120
IPGPAFNPASHPASAPTSSSSSAFRPVMPSRQIVERQPRMLDFRVEYRDRNVDVVLEDTC
Sbjct: 61 IPGPAFNPASHPASAPTSSSSSAFRPVMPSRQIVERQPRMLDFRVEYRDRNVDVVLEDTC 120
Query: 121 TVGEIKQILENELQIPVSKMLLKGWKTGDVEDSTVLKSLHLPKNNSLYVLTPDLPPPSSS 180
TVGEIKQILENELQIPVSKMLLKGWKTGDVEDSTVLKSLHLPKNNSLYVLTPDLPPPSSS
Sbjct: 121 TVGEIKQILENELQIPVSKMLLKGWKTGDVEDSTVLKSLHLPKNNSLYVLTPDLPPPSSS 180
Query: 181 SHAGALQESLNQNFMLIITHREVQREYNLNFSGSSTIQEVKRNVYDLTSIPVRHQLWEGW 240
SHAGALQESLNQNFMLIITHREVQREYNLNFSGSSTIQEVKRNVYDLTSIPVRHQLWEGW
Sbjct: 181 SHAGALQESLNQNFMLIITHREVQREYNLNFSGSSTIQEVKRNVYDLTSIPVRHQLWEGW 240
Query: 241 PTSATDDSMCLAESGLSYPCHRLTVGRRSSPAQTREQSEEQITDVHMVSDSDGDDFEDAT 300
PTSATDDSMCLAESGLSYPCHRLTVGRRSSPAQTREQSEEQITDVHMVSDSDGDDFEDAT
Sbjct: 241 PTSATDDSMCLAESGLSYPCHRLTVGRRSSPAQTREQSEEQITDVHMVSDSDGDDFEDAT 300
Query: 301 EFGVDDGEVFGMASSALRKSPMMPENAENEGDALLQFTAEFSSRYGDCHPVFFIGSLEAA 360
EFGVDDGEVFGMASSALRKSPMMPENAENEGDALLQFTAEFSSRYGDCHPVFFIGSLEAA
Sbjct: 301 EFGVDDGEVFGMASSALRKSPMMPENAENEGDALLQFTAEFSSRYGDCHPVFFIGSLEAA 360
Query: 361 FQEAFYVKARDRKLLAIYLHHDESVLTNVFCSQMLCAESIVSYLSQNFITWAWDLTKDSN 420
FQEAFYVKARDRKLLAIYLHHDESVLTNVFCSQMLCAESIVSYLSQNFITWAWDLTKDSN
Sbjct: 361 FQEAFYVKARDRKLLAIYLHHDESVLTNVFCSQMLCAESIVSYLSQNFITWAWDLTKDSN 420
Query: 421 RARFLTMCNRHFGSVVAQTIRTQKTDQFPLFLIIMGKRSSNEVLNVIQGNTTVDELMMRL 480
RARFLTMCNRHFGSVVAQTIRTQKTDQFPLFLIIMGKRSSNEVLNVIQGNTTVDELMMRL
Sbjct: 421 RARFLTMCNRHFGSVVAQTIRTQKTDQFPLFLIIMGKRSSNEVLNVIQGNTTVDELMMRL 480
Query: 481 MAAMEIFTAQQQEDIKDEDEREARENVKREQDEAYRLSLEADRAKREAHEREMAEQFRLE 540
MAAMEIFTAQQQEDIKDEDEREARENVKREQDEAYRLSLEADRAKREAHEREMAEQFRLE
Sbjct: 481 MAAMEIFTAQQQEDIKDEDEREARENVKREQDEAYRLSLEADRAKREAHEREMAEQFRLE 540
Query: 541 QIRKEQEEEREAIRLSLEQALPPEPKEENAEPVSKLRIRTPSGEFLERRFLASNKLQIVF 600
QIRKEQEEEREAIRLSLEQALPPEPKEENAEPVSKLRIRTPSGEFLERRFLASNKLQIVF
Sbjct: 541 QIRKEQEEEREAIRLSLEQALPPEPKEENAEPVSKLRIRTPSGEFLERRFLASNKLQIVF 600
Query: 601 DFVASKGFPWDEYKLLSTFPRRDVTQLDPNKSLLEVKLFPQETLFLEAKE 650
DFVASKGFPWDEYKLLSTFPRRDVTQLDPNKSLLEVKLFPQETLFLEAKE
Sbjct: 601 DFVASKGFPWDEYKLLSTFPRRDVTQLDPNKSLLEVKLFPQETLFLEAKE 650
>gi|24797106 UBX domain containing 8 [Homo sapiens]
Length = 445
Score = 127 bits (320), Expect = 2e-29
Identities = 97/352 (27%), Positives = 169/352 (48%), Gaps = 35/352 (9%)
Query: 308 EVFGMASSALRKSPMMPENAENEGDALLQFTAEFSSRYGDCHPVFFIGSLEAAFQEAFYV 367
++F A +R P + GD ++ F F +YG HPVF+ G+ A +A
Sbjct: 112 DIFRFALRFIRPDPRS-RVTDPVGD-IVSFMHSFEEKYGRAHPVFYQGTYSQALNDA--- 166
Query: 368 KARDRKLLAIYLHHDESVLTNVFCSQMLCAESIVSYLSQNFITWAWDLTKDSNRARFLTM 427
R+ + L +YLH D+ ++ FC LCA ++S ++ + WA K
Sbjct: 167 -KRELRFLLVYLHGDDHQDSDEFCRNTLCAPEVISLINTRMLFWACSTNKPE-------- 217
Query: 428 CNRHFGSVVAQTIRTQKTDQFPLFLIIMGKRSSNEVLNVIQGNTTVDELMMRLMAAMEIF 487
G V+Q +R + +P +IM K V+ ++G D+L+ +L M+
Sbjct: 218 -----GYRVSQALRE---NTYPFLAMIMLKDRRMTVVGRLEGLIQPDDLINQLTFIMDAN 269
Query: 488 TAQQQEDIKDEDEREARENVKREQDEAYRLSLEAD----RAKREAHEREMAEQFRLEQIR 543
+ + +ER + ++++QDEAY SL AD R KRE ER+ ++ ++Q +
Sbjct: 270 QTYLVSERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQK 329
Query: 544 KEQEEEREAIRLSLE---QALPPEPKEENAEPVSKLRIRTPSGEFLERRFLASNKLQIVF 600
+E R+ ++ E + LPPEP ++ E V K+ + P+ +ERRF S L ++
Sbjct: 330 LAEERRRQNLQEEKERKLECLPPEPSPDDPESV-KIIFKLPNDSRVERRFHFSQSLTVIH 388
Query: 601 DFVASKGFPWDEYKLLSTFPRRDVTQLD----PN-KSLLEVKLFPQETLFLE 647
DF+ S +++++ + FPRR + + PN +L E L E LF++
Sbjct: 389 DFLFSLKESPEKFQIEANFPRRVLPCIPSEEWPNPPTLQEAGLSHTEVLFVQ 440
Score = 39.3 bits (90), Expect = 0.011
Identities = 32/107 (29%), Positives = 48/107 (44%), Gaps = 26/107 (24%)
Query: 11 LADFQACTGIENIDEAITLLEQNNWDLVAAINGVIPQENGILQSEYGGETIPGPAFNPAS 70
L FQ TGIE++D+ LEQ+NW++ AA+ + ++ G+ FNP
Sbjct: 17 LLQFQDLTGIESMDQCRHTLEQHNWNIEAAVQDRLNEQEGV-----------PSVFNP-- 63
Query: 71 HPASAPTSSSSSAFRPVMPSRQIVERQPR----------MLDFRVEY 107
P S P +++ R + S + QPR ML FR Y
Sbjct: 64 -PPSRPLQVNTADHR--IYSYVVSRPQPRGLLGWGYYLIMLPFRFTY 107
>gi|5031651 reproduction 8 [Homo sapiens]
Length = 270
Score = 58.5 bits (140), Expect = 2e-08
Identities = 49/158 (31%), Positives = 72/158 (45%), Gaps = 10/158 (6%)
Query: 501 REARENVKREQDEAYRLS----LEADRAKR----EAHEREMAEQFRLEQIRKEQEEEREA 552
R+ E + EA++LS L D E RE A+ L + E E
Sbjct: 112 RKLEERFYQMTGEAWKLSSGHKLGGDEGTSQTSFETSNREAAKSQNLPKPLTEFPSPAEQ 171
Query: 553 IRLSLEQALPPEPKEENAEPVSKLRIRTPSGEFLERRFLASNKLQIVFDFVASKGFPWDE 612
LP EP + AE V + +R PSG L RRFL S Q++FD++ G+
Sbjct: 172 PTCKEIPDLPEEPSQ-TAEEVVTVALRCPSGNVLRRRFLKSYSSQVLFDWMTRIGYHISL 230
Query: 613 YKLLSTFPRRDVTQLDPNKSLLEVKLFPQETLFLEAKE 650
Y L ++FPRR + ++ +SL ++ + L LE KE
Sbjct: 231 YSLSTSFPRRPLA-VEGGQSLEDIGITVDTVLILEEKE 267
>gi|24307965 UBX domain containing 2 [Homo sapiens]
Length = 508
Score = 56.6 bits (135), Expect = 7e-08
Identities = 50/220 (22%), Positives = 99/220 (45%), Gaps = 30/220 (13%)
Query: 456 GKRSSNEVLNVIQGNTTVDELMMRLMAAMEIFTAQQQEDIKDEDEREARENV-------- 507
G +S++ + ++L +R+ + +++E K+E++RE ++ +
Sbjct: 175 GHATSSQEPSGCSDQRPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKE 234
Query: 508 ----KREQDEAYRLSLEADRAKREAHEREMAEQFRLEQIR-------------KEQEEER 550
KR+Q+E + +R + +A +R E+ + +QI KE+ E
Sbjct: 235 MLDYKRKQEEELTKRMLEERNREKAEDRAARERIK-QQIALDRAERAARFAKTKEEVEAA 293
Query: 551 EAIRLSLEQALPPEPKEENAEP---VSKLRIRTPSGEFLERRFLASNKLQIVFDFVASK- 606
+A L +QA +E A V++++ R P G +F + L+ F A
Sbjct: 294 KAAALLAKQAEMEVKRESYARERSTVARIQFRLPDGSSFTNQFPSDAPLEEARQFAAQTV 353
Query: 607 GFPWDEYKLLSTFPRRDVTQLDPNKSLLEVKLFPQETLFL 646
G + + L + FPRR+ T+ D K LL+++L P ++ L
Sbjct: 354 GNTYGNFSLATMFPRREFTKEDYKKKLLDLELAPSASVVL 393
>gi|149944496 UBX domain containing 7 [Homo sapiens]
Length = 489
Score = 56.6 bits (135), Expect = 7e-08
Identities = 48/189 (25%), Positives = 87/189 (46%), Gaps = 17/189 (8%)
Query: 468 QGNTTVDELMMRLMAAMEIFTAQQQEDIKDEDEREARENVKREQDEAYRLSLEADRAKRE 527
Q + + +E L + E F + D ++E E A+ +D +R +E
Sbjct: 310 QDSRSDEESESELFSGSEEFISVCGSDEEEEVENLAKSRKSPHKDLGHR---------KE 360
Query: 528 AHEREMAEQ-FRLEQIRKEQEEEREAIRLSLEQALPPEPKEENAE------PVSKLRIRT 580
+ R + E R + + A+ + + +PPE + E P ++L +R
Sbjct: 361 ENRRPLTEPPVRTDPGTATNHQGLPAVDSEILE-MPPEKADGVVEGIDVNGPKAQLMLRY 419
Query: 581 PSGEFLERRFLASNKLQIVFDFVASKGFPWDEYKLLSTFPRRDVTQLDPNKSLLEVKLFP 640
P G+ + KL + V SKG+P + ++LL+ FPRR ++ LD + +L E L P
Sbjct: 420 PDGKREQITLPEQAKLLALVKHVQSKGYPNERFELLTNFPRRKLSHLDYDITLQEAGLCP 479
Query: 641 QETLFLEAK 649
QET+F++ +
Sbjct: 480 QETVFVQER 488
>gi|21361517 UBX domain protein 1 [Homo sapiens]
Length = 312
Score = 53.5 bits (127), Expect = 6e-07
Identities = 55/179 (30%), Positives = 82/179 (45%), Gaps = 31/179 (17%)
Query: 489 AQQQEDIKDEDEREA--RENVKREQDE---AYRLSLEADRAKREAHER--EMAEQFRLEQ 541
AQ+Q + ++ +EREA RE +R Q + A R L+ D +R A ER E AE+ Q
Sbjct: 103 AQKQREREEREEREALERERQRRRQGQELSAARQRLQEDEMRRAAEERRREKAEELAARQ 162
Query: 542 IRKEQEEEREAIRL-----SLEQALP-------PEPKEENAEPVSK-------LRIRTPS 582
+E+ E +A R S+ P P P + EP +K +++R P
Sbjct: 163 RVREKIERDKAERAKKYGGSVGSQPPPVAPEPGPVPSSPSQEPPTKREYDQCRIQVRLPD 222
Query: 583 GEFLERRFLASNKLQIVFDFV-----ASKGFPWDEYKLLSTFPRRDVTQLDPNKSLLEV 636
G L + F A +L V +V G D +LLS FPRR ++ D + L E+
Sbjct: 223 GTSLTQTFRAREQLAAVRLYVELHRGEELGGGQDPVQLLSGFPRRAFSEADMERPLQEL 281
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 51.6 bits (122), Expect = 2e-06
Identities = 32/89 (35%), Positives = 53/89 (59%), Gaps = 4/89 (4%)
Query: 489 AQQQEDIKDEDEREARENVKREQDEAYRLSLEADRAKREAHEREMAEQFRLEQIR--KEQ 546
A+++ + + +E+EARE + EQ+E RL + + A EA RE AE+ RLE+ + ++Q
Sbjct: 644 AEREAEARRREEQEAREKAQAEQEEQERLQKQKEEA--EARSREEAERQRLEREKHFQQQ 701
Query: 547 EEEREAIRLSLEQALPPEPKEENAEPVSK 575
E+ER+ R LE+ + K E +E K
Sbjct: 702 EQERQERRKRLEEIMKRTRKSEVSETKQK 730
Score = 38.5 bits (88), Expect = 0.020
Identities = 31/90 (34%), Positives = 48/90 (53%), Gaps = 3/90 (3%)
Query: 471 TTVDELMMRLMAAMEIFTAQQQEDIKDEDEREARENVKREQDEAYRLSLEADRAKREAHE 530
TT E RL+A A++Q + ++++ R E KR ++E EA RA+REA
Sbjct: 593 TTDREEATRLLAEKRR-QAREQREREEQERRLQAERDKRMREEQLAREAEA-RAEREAEA 650
Query: 531 REMAEQFRLEQIRKEQEEEREAIRLSLEQA 560
R EQ E+ + EQEE+ E ++ E+A
Sbjct: 651 RRREEQEAREKAQAEQEEQ-ERLQKQKEEA 679
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 50.4 bits (119), Expect = 5e-06
Identities = 36/129 (27%), Positives = 65/129 (50%), Gaps = 2/129 (1%)
Query: 462 EVLNVIQGNTTVDELMMRLMAAMEIFTAQQQEDIKDEDEREARENVKREQDEAYRLSLEA 521
EVLN + T+ +L A ++ +Q++ +I+ +E + + E++ R +E
Sbjct: 109 EVLNSQETGPTLPRQNSQLPAQVQNGPSQEELEIQRRQLQEQQRQKELERERLERERMER 168
Query: 522 DRAKREAHEREMAEQFRL--EQIRKEQEEEREAIRLSLEQALPPEPKEENAEPVSKLRIR 579
+R +RE ERE E+ RL EQ+ +E++E RL ++ L + + E E + + R
Sbjct: 169 ERLERERLERERLERERLEQEQLERERQERERQERLERQERLERQERLERQERLDRERQE 228
Query: 580 TPSGEFLER 588
E LER
Sbjct: 229 RQERERLER 237
Score = 45.4 bits (106), Expect = 2e-04
Identities = 40/138 (28%), Positives = 70/138 (50%), Gaps = 7/138 (5%)
Query: 458 RSSNEVLNVIQGNTTVDELMMRLMAAMEIFTAQQQEDIKDEDEREARENVKREQDEAYRL 517
R ++++ +Q + +EL ++ E ++ E + E ER RE ++RE+ E R
Sbjct: 122 RQNSQLPAQVQNGPSQEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERER- 180
Query: 518 SLEADRAKREAHEREMAEQFRLEQIRKEQEEEREAIRLSLEQALPPEPKE----ENAEPV 573
LE +R ++E ERE E+ R E++ +++ ER+ RL ++ L E +E E E +
Sbjct: 181 -LERERLEQEQLERERQERERQERLERQERLERQE-RLERQERLDRERQERQERERLERL 238
Query: 574 SKLRIRTPSGEFLERRFL 591
+ R E LER L
Sbjct: 239 ERERQERERQEQLEREQL 256
Score = 37.4 bits (85), Expect = 0.044
Identities = 24/73 (32%), Positives = 40/73 (54%), Gaps = 6/73 (8%)
Query: 490 QQQEDIKDEDEREARENVKR----EQDEAYRLSLEADRAKREAHEREMAEQFRLEQIRKE 545
+Q++ ++ ERE +E ++R E+ E DR ++E ERE E RLE+ R+E
Sbjct: 187 EQEQLERERQERERQERLERQERLERQERLERQERLDRERQERQERERLE--RLERERQE 244
Query: 546 QEEEREAIRLSLE 558
+E + + R LE
Sbjct: 245 RERQEQLEREQLE 257
Score = 34.7 bits (78), Expect = 0.28
Identities = 21/67 (31%), Positives = 36/67 (53%), Gaps = 6/67 (8%)
Query: 490 QQQEDIKDEDEREARENVKREQDEAYRLSLEADRAKREAHEREMAEQFRLEQIRKEQEEE 549
++QE ++ ++ E +E + RE+ E +R + E ERE E+ R EQ+ +EQ E
Sbjct: 205 ERQERLERQERLERQERLDRERQE------RQERERLERLERERQERERQEQLEREQLEW 258
Query: 550 REAIRLS 556
R+S
Sbjct: 259 ERERRIS 265
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 50.4 bits (119), Expect = 5e-06
Identities = 36/129 (27%), Positives = 65/129 (50%), Gaps = 2/129 (1%)
Query: 462 EVLNVIQGNTTVDELMMRLMAAMEIFTAQQQEDIKDEDEREARENVKREQDEAYRLSLEA 521
EVLN + T+ +L A ++ +Q++ +I+ +E + + E++ R +E
Sbjct: 109 EVLNSQETGPTLPRQNSQLPAQVQNGPSQEELEIQRRQLQEQQRQKELERERLERERMER 168
Query: 522 DRAKREAHEREMAEQFRL--EQIRKEQEEEREAIRLSLEQALPPEPKEENAEPVSKLRIR 579
+R +RE ERE E+ RL EQ+ +E++E RL ++ L + + E E + + R
Sbjct: 169 ERLERERLERERLERERLEQEQLERERQERERQERLERQERLERQERLERQERLDRERQE 228
Query: 580 TPSGEFLER 588
E LER
Sbjct: 229 RQERERLER 237
Score = 45.4 bits (106), Expect = 2e-04
Identities = 40/138 (28%), Positives = 70/138 (50%), Gaps = 7/138 (5%)
Query: 458 RSSNEVLNVIQGNTTVDELMMRLMAAMEIFTAQQQEDIKDEDEREARENVKREQDEAYRL 517
R ++++ +Q + +EL ++ E ++ E + E ER RE ++RE+ E R
Sbjct: 122 RQNSQLPAQVQNGPSQEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERER- 180
Query: 518 SLEADRAKREAHEREMAEQFRLEQIRKEQEEEREAIRLSLEQALPPEPKE----ENAEPV 573
LE +R ++E ERE E+ R E++ +++ ER+ RL ++ L E +E E E +
Sbjct: 181 -LERERLEQEQLERERQERERQERLERQERLERQE-RLERQERLDRERQERQERERLERL 238
Query: 574 SKLRIRTPSGEFLERRFL 591
+ R E LER L
Sbjct: 239 ERERQERERQEQLEREQL 256
Score = 37.4 bits (85), Expect = 0.044
Identities = 24/73 (32%), Positives = 40/73 (54%), Gaps = 6/73 (8%)
Query: 490 QQQEDIKDEDEREARENVKR----EQDEAYRLSLEADRAKREAHEREMAEQFRLEQIRKE 545
+Q++ ++ ERE +E ++R E+ E DR ++E ERE E RLE+ R+E
Sbjct: 187 EQEQLERERQERERQERLERQERLERQERLERQERLDRERQERQERERLE--RLERERQE 244
Query: 546 QEEEREAIRLSLE 558
+E + + R LE
Sbjct: 245 RERQEQLEREQLE 257
Score = 34.7 bits (78), Expect = 0.28
Identities = 21/67 (31%), Positives = 36/67 (53%), Gaps = 6/67 (8%)
Query: 490 QQQEDIKDEDEREARENVKREQDEAYRLSLEADRAKREAHEREMAEQFRLEQIRKEQEEE 549
++QE ++ ++ E +E + RE+ E +R + E ERE E+ R EQ+ +EQ E
Sbjct: 205 ERQERLERQERLERQERLDRERQE------RQERERLERLERERQERERQEQLEREQLEW 258
Query: 550 REAIRLS 556
R+S
Sbjct: 259 ERERRIS 265
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 48.5 bits (114), Expect = 2e-05
Identities = 27/75 (36%), Positives = 44/75 (58%), Gaps = 4/75 (5%)
Query: 490 QQQEDIKDEDEREARENVKREQDEAYRLSLEADRAKREAHEREMAEQFRLEQIRKEQEEE 549
+QQE+ +++ ER ++ +REQ +L E + + + RE E+ R +Q+R+EQEEE
Sbjct: 316 EQQEERREQQERREQQEERREQ----QLRREQEERREQQLRREQEEERREQQLRREQEEE 371
Query: 550 REAIRLSLEQALPPE 564
R +L EQ L E
Sbjct: 372 RREQQLRREQQLRRE 386
Score = 45.4 bits (106), Expect = 2e-04
Identities = 31/82 (37%), Positives = 42/82 (51%), Gaps = 10/82 (12%)
Query: 490 QQQEDIKDEDEREARENVKREQDEAYRLSLEADRAKREAHEREMAEQFRLEQIRKEQEEE 549
+QQ K E+ER ++ +REQ E E +RE R E+ R +Q+R+EQEEE
Sbjct: 303 EQQLRRKQEEERREQQEERREQQERR----EQQEERREQQLRREQEERREQQLRREQEEE 358
Query: 550 REAIRLSLEQALPPEPKEENAE 571
R EQ L E +EE E
Sbjct: 359 RR------EQQLRREQEEERRE 374
Score = 43.9 bits (102), Expect = 5e-04
Identities = 29/89 (32%), Positives = 46/89 (51%), Gaps = 7/89 (7%)
Query: 490 QQQEDIKDEDEREARENVKREQDEAYRLSLEAD-RAKREAHEREMAEQFRLEQIRKEQEE 548
+++E ++ + +E R + E+ + RL E R K+E RE E+ R +Q R+EQ+E
Sbjct: 273 EEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQE 332
Query: 549 EREAIRL------SLEQALPPEPKEENAE 571
ER +L EQ L E +EE E
Sbjct: 333 ERREQQLRREQEERREQQLRREQEEERRE 361
Score = 42.7 bits (99), Expect = 0.001
Identities = 43/151 (28%), Positives = 71/151 (47%), Gaps = 20/151 (13%)
Query: 457 KRSSNEVLNVIQGNTTV---DELMMRLMAAMEIFTAQQQED-----------IKDEDERE 502
+R+ E L +G+ T DE +R +E+ ++E ++E+E+E
Sbjct: 186 RRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKE 245
Query: 503 --ARENVKREQDEAYRLSLEADRAKREAHERE--MAEQFRLEQIRKEQEEEREAIRLSLE 558
RE V R+++E +L E + +RE E E + + R E R+ QEEE++ RL E
Sbjct: 246 WRKRETVLRKEEE--KLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRRE 303
Query: 559 QALPPEPKEENAEPVSKLRIRTPSGEFLERR 589
Q L + +EE E + R + E E R
Sbjct: 304 QQLRRKQEEERREQQEERREQQERREQQEER 334
Score = 42.0 bits (97), Expect = 0.002
Identities = 28/98 (28%), Positives = 50/98 (51%), Gaps = 7/98 (7%)
Query: 479 RLMAAMEIFTAQQQEDIKDEDEREAREN-VKREQDEAYRLSLEADRAKREAHEREMAEQF 537
+L ++ Q++E + + E+E RE +KREQ+E D KRE ++
Sbjct: 418 QLRREQQLRREQEEERHEQKHEQERREQRLKREQEE------RRDWLKREEETERHEQER 471
Query: 538 RLEQIRKEQEEEREAIRLSLEQALPPEPKEENAEPVSK 575
R +Q++++QEEER L LE+ E +E + + +
Sbjct: 472 RKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRR 509
Score = 42.0 bits (97), Expect = 0.002
Identities = 27/108 (25%), Positives = 56/108 (51%), Gaps = 8/108 (7%)
Query: 490 QQQEDIKDEDEREARENVKREQDEAYR---LSLEADRAKREAHEREMA-----EQFRLEQ 541
+++E+ + ++ ++ +KR+Q+E R L LE + + + RE E+ R ++
Sbjct: 459 KREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQR 518
Query: 542 IRKEQEEEREAIRLSLEQALPPEPKEENAEPVSKLRIRTPSGEFLERR 589
+++++EEER RL EQ L E +E + + + + E E+R
Sbjct: 519 LKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQR 566
Score = 40.8 bits (94), Expect = 0.004
Identities = 36/101 (35%), Positives = 49/101 (48%), Gaps = 22/101 (21%)
Query: 490 QQQEDIKDEDEREARENVKREQDEAYRLSLEA---DRAKREAHEREMAEQF--------- 537
++Q+ +K E E + +KRE+ E RL E R KRE E E +Q
Sbjct: 585 RRQQRLKREQEERLEQRLKREEVE--RLEQEERREQRLKREEPEEERRQQLLKSEEQEER 642
Query: 538 RLEQIRKEQEEEREAIRLS-------LEQALPPEPKEENAE 571
R +Q+R+EQ+E RE RL LEQ L E +EE E
Sbjct: 643 RQQQLRREQQERREQ-RLKREEEEERLEQRLKREHEEERRE 682
Score = 39.3 bits (90), Expect = 0.011
Identities = 30/87 (34%), Positives = 44/87 (50%), Gaps = 4/87 (4%)
Query: 488 TAQQQEDIKDEDEREARENVKREQDEAYRLSLEADRAKREAHEREMAEQ-FRLEQI--RK 544
T ++E+ K ++E R+ +E++E R LE +RE E E +Q R EQ RK
Sbjct: 251 TVLRKEEEKLQEEEPQRQRELQEEEEQLR-KLERQELRRERQEEEQQQQRLRREQQLRRK 309
Query: 545 EQEEEREAIRLSLEQALPPEPKEENAE 571
++EE RE EQ E +EE E
Sbjct: 310 QEEERREQQEERREQQERREQQEERRE 336
Score = 39.3 bits (90), Expect = 0.011
Identities = 26/83 (31%), Positives = 43/83 (51%), Gaps = 2/83 (2%)
Query: 490 QQQEDIKDEDEREARENVKREQDEAYRLSLEADRAKREAHEREMAEQFRLE-QIRKEQEE 548
+Q+E+ +++ R +E +REQ L ++ R + +Q R E Q+R+EQ+
Sbjct: 354 EQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 413
Query: 549 EREAIRLSLEQALPPEPKEENAE 571
RE +L EQ L E +EE E
Sbjct: 414 RREQ-QLRREQQLRREQEEERHE 435
Score = 38.1 bits (87), Expect = 0.026
Identities = 34/116 (29%), Positives = 59/116 (50%), Gaps = 20/116 (17%)
Query: 474 DELMMRLMAAMEIFTAQQQED---IKDEDER----EAREN-VKREQDEAYRLSLEAD--- 522
+ L RL + ++ Q++ +K E+E+ E RE +KREQ+E L+ +
Sbjct: 526 ERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEER 585
Query: 523 ---RAKREAHEREMAEQFRLEQIRKEQEEEREAIRLSLEQALPPEPKEENAEPVSK 575
R KRE ER + ++ + E++ + ++EER RL E EP+EE + + K
Sbjct: 586 RQQRLKREQEER-LEQRLKREEVERLEQEERREQRLKRE-----EPEEERRQQLLK 635
Score = 37.7 bits (86), Expect = 0.033
Identities = 27/91 (29%), Positives = 48/91 (52%), Gaps = 8/91 (8%)
Query: 490 QQQEDIKDEDE---REARENVKREQDEAYRLSLEADRAKREAHEREMAEQFRLEQI--RK 544
Q+Q ++++E+E + R+ ++RE+ E + + R +RE R E+ R EQ R+
Sbjct: 266 QRQRELQEEEEQLRKLERQELRRERQEEEQ---QQQRLRREQQLRRKQEEERREQQEERR 322
Query: 545 EQEEEREAIRLSLEQALPPEPKEENAEPVSK 575
EQ+E RE EQ L E +E + + +
Sbjct: 323 EQQERREQQEERREQQLRREQEERREQQLRR 353
Score = 37.0 bits (84), Expect = 0.057
Identities = 25/78 (32%), Positives = 44/78 (56%), Gaps = 4/78 (5%)
Query: 490 QQQEDIKDEDEREARENVKREQDEA--YRLSLEADRAKREAHEREMAEQFRLE-QIRKEQ 546
++Q++ +++ E + ++REQ+E +L E + +RE R E+ R E Q+R+EQ
Sbjct: 322 REQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQ 381
Query: 547 EEEREAIRLSLEQALPPE 564
+ RE +L EQ L E
Sbjct: 382 QLRREQ-QLRREQQLRRE 398
Score = 37.0 bits (84), Expect = 0.057
Identities = 26/100 (26%), Positives = 50/100 (50%), Gaps = 2/100 (2%)
Query: 490 QQQEDIKDEDEREARENVKREQD-EAYRLSLEADRAKREAHEREMAEQFRLEQIRKEQEE 548
++++ +K E E E R+ +KRE++ E + + KR+ E +LE+ + +++
Sbjct: 442 RREQRLKREQE-ERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQ 500
Query: 549 EREAIRLSLEQALPPEPKEENAEPVSKLRIRTPSGEFLER 588
ER +L EQ E + + E +L+ R S + L R
Sbjct: 501 ERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRR 540
Score = 37.0 bits (84), Expect = 0.057
Identities = 26/108 (24%), Positives = 53/108 (49%), Gaps = 7/108 (6%)
Query: 490 QQQEDIKDEDEREARENVKREQDEAYRLSLEADRAKREAHEREMAEQFRLEQIRKEQEEE 549
+Q+E+ + + + + ++REQ+E L+ + KR ER R +++++EQEE
Sbjct: 521 RQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQER------REQRLKREQEER 574
Query: 550 REAIRLSLEQALPPEPKEENAEPVSKLRIRTPSGEFLERRFLASNKLQ 597
R+ + E+ K E E + + R++ E LE+ +L+
Sbjct: 575 RDQLLKREEERRQQRLKREQEERLEQ-RLKREEVERLEQEERREQRLK 621
Score = 37.0 bits (84), Expect = 0.057
Identities = 27/100 (27%), Positives = 53/100 (53%), Gaps = 13/100 (13%)
Query: 490 QQQEDIKDEDEREARENVKREQDEAYRLSLEADRAKREAHEREMA---EQFRLEQ-IRKE 545
++Q ++E E E R+ + + +++ R + R ++E E+ + E+ RLEQ +++E
Sbjct: 616 REQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKRE 675
Query: 546 QEEEREAIRLSLEQALPPEPKEENAEPVSKLRIRTPSGEF 585
EEER EQ L E +E+ E +++ R P ++
Sbjct: 676 HEEERR------EQELAEEEQEQARE---RIKSRIPKWQW 706
Score = 37.0 bits (84), Expect = 0.057
Identities = 20/72 (27%), Positives = 42/72 (58%), Gaps = 5/72 (6%)
Query: 485 EIFTAQQQEDIKDEDEREARENVKREQDEAYRLSLEADRAKREAHEREMAEQFRLEQ--- 541
++ ++++ + E ER+ RE + +Q+E L E ++ +R+ ER+ E+ L+Q
Sbjct: 1122 QLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEE 1181
Query: 542 --IRKEQEEERE 551
+R+EQE+ R+
Sbjct: 1182 QLLREEQEKRRQ 1193
Score = 36.6 bits (83), Expect = 0.074
Identities = 24/76 (31%), Positives = 41/76 (53%), Gaps = 6/76 (7%)
Query: 490 QQQEDIKDEDEREARENVKREQDEAYRLSLEADRAKREAHEREMAEQFRLE-QIRKEQEE 548
++++ ++ E E + ++REQ+E R + +RE E +Q R E Q+R+EQ+
Sbjct: 334 RREQQLRREQEERREQQLRREQEEERR----EQQLRREQEEERREQQLRREQQLRREQQL 389
Query: 549 EREAIRLSLEQALPPE 564
RE +L EQ L E
Sbjct: 390 RREQ-QLRREQQLRRE 404
Score = 36.6 bits (83), Expect = 0.074
Identities = 25/86 (29%), Positives = 45/86 (52%), Gaps = 14/86 (16%)
Query: 490 QQQEDIKDE----DEREARENVKREQDEAYRLSLEADRAKREAHEREMAEQFRLEQIRKE 545
++QE+ +D+ +E ++ +KREQ+E R KRE ER E+ R +++++E
Sbjct: 569 REQEERRDQLLKREEERRQQRLKREQEERLE-----QRLKREEVERLEQEERREQRLKRE 623
Query: 546 QEEEREAIRLSLEQALPPEPKEENAE 571
+ EE +Q L E +EE +
Sbjct: 624 EPEEERR-----QQLLKSEEQEERRQ 644
Score = 36.6 bits (83), Expect = 0.074
Identities = 33/102 (32%), Positives = 52/102 (50%), Gaps = 10/102 (9%)
Query: 474 DELMMRLMAAMEIFTAQQQEDIKDEDEREARENVKREQDEAYRLSLEADRAKREAHEREM 533
+E + R A ++ Q++ED ED+ E R + ++ +D+ +R LE +R KR H
Sbjct: 837 EEQLQRRERAQQL---QEEEDGLQEDQ-ERRRSQEQRRDQKWRWQLEEER-KRRRHTL-Y 890
Query: 534 AEQFRLEQIRKEQ----EEEREAIRLSLEQALPPEPKEENAE 571
A+ EQ+RKEQ EEE E R E+ E + + E
Sbjct: 891 AKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYRE 932
Score = 36.6 bits (83), Expect = 0.074
Identities = 24/96 (25%), Positives = 48/96 (50%), Gaps = 16/96 (16%)
Query: 496 KDEDEREARENVKREQDEAYRLSLEADRAKREAHEREMAEQFRLEQ-----IRKEQEE-- 548
+ E ER+ R+ + +Q+E L E ++ +R+ ER+ E+ L+Q +R+E+E+
Sbjct: 1073 RQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRR 1132
Query: 549 ---------EREAIRLSLEQALPPEPKEENAEPVSK 575
E E ++ EQ L EP++ + + +
Sbjct: 1133 RQELERQYREEEEVQQEEEQLLREEPEKRRRQELER 1168
Score = 36.2 bits (82), Expect = 0.097
Identities = 27/117 (23%), Positives = 59/117 (50%), Gaps = 5/117 (4%)
Query: 485 EIFTAQQQEDIKDEDEREARENVKREQDEAYRLSLEADRAKREAHEREMAEQFRL----E 540
E+ ++++ + E ER+ RE + +Q+E L E ++ +R+ ER+ + +L E
Sbjct: 912 ELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEE 971
Query: 541 QIRKEQEEEREAIRLSLEQALPPEPKEENAEPVSKLRIRTPSGEFLERRFLASNKLQ 597
Q+ E+ E+R + E ++E + + + R + E+ ER++ ++LQ
Sbjct: 972 QLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEW-ERQYRKKDELQ 1027
Score = 35.8 bits (81), Expect = 0.13
Identities = 29/105 (27%), Positives = 51/105 (48%), Gaps = 3/105 (2%)
Query: 496 KDEDEREARENVKREQDEAYRLSLEADRAKREAHEREMAEQFRLEQIRKE-QEEEREAIR 554
+ E E++ RE + +Q+E L E ++ +R+ ER+ ++ L+Q ++ EERE R
Sbjct: 983 RQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRR 1042
Query: 555 LSLEQALPPEPKEENAEPVSKL--RIRTPSGEFLERRFLASNKLQ 597
L + E +E E L T + LER++ +LQ
Sbjct: 1043 LQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQ 1087
Score = 35.8 bits (81), Expect = 0.13
Identities = 25/115 (21%), Positives = 55/115 (47%), Gaps = 2/115 (1%)
Query: 485 EIFTAQQQEDIKDEDEREARENVKREQDEAYRLSLEADRAKREAHEREMAEQFRLEQIRK 544
++ + ++ + E ER+ RE + +Q+E L E ++ +R+ ER+ E+ ++Q +
Sbjct: 1092 QLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEE 1151
Query: 545 E--QEEEREAIRLSLEQALPPEPKEENAEPVSKLRIRTPSGEFLERRFLASNKLQ 597
+ +EE + R LE+ E + + E + + ER++ +LQ
Sbjct: 1152 QLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQ 1206
Score = 35.8 bits (81), Expect = 0.13
Identities = 21/64 (32%), Positives = 38/64 (59%), Gaps = 4/64 (6%)
Query: 490 QQQED--IKDEDEREARENVKREQDEAYRLSLEADRAKREAHEREMAEQFRLEQIRKEQE 547
QQ+E+ +++E E+ R+ ++R+ E L E ++ RE E+E Q R Q R+E+E
Sbjct: 1147 QQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLRE--EQEKRRQERERQYREEEE 1204
Query: 548 EERE 551
+R+
Sbjct: 1205 LQRQ 1208
Score = 35.4 bits (80), Expect = 0.17
Identities = 21/76 (27%), Positives = 44/76 (57%), Gaps = 5/76 (6%)
Query: 490 QQQEDIKDEDEREARENVKREQ---DEAYRLSLEADRAKREAHEREMAEQFRLEQIRKEQ 546
+Q+ + K +E + R+ ++EQ E YR LE ++ + E E+++ Q R + R+E+
Sbjct: 1718 RQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEE 1777
Query: 547 E--EEREAIRLSLEQA 560
+ +ERE +L +++
Sbjct: 1778 QLRQEREEQQLRSQES 1793
Score = 34.7 bits (78), Expect = 0.28
Identities = 23/86 (26%), Positives = 47/86 (54%), Gaps = 3/86 (3%)
Query: 485 EIFTAQQQEDIKDEDEREARENVKREQDEAYRLSLEADRAKREAHEREMAEQFRLEQIRK 544
++ + ++ + E ER+ RE + +Q+E L E ++ +R+ ER+ E+ L++ ++
Sbjct: 1152 QLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEK-RRQERERQYREEEELQRQKR 1210
Query: 545 EQEEEREAIRLSLEQALPPEPKEENA 570
+Q E R L+ EP++ENA
Sbjct: 1211 KQRYRDEDQRSDLKWQW--EPEKENA 1234
Score = 34.3 bits (77), Expect = 0.37
Identities = 22/97 (22%), Positives = 49/97 (50%), Gaps = 11/97 (11%)
Query: 490 QQQEDIKDEDEREARENVKREQDEAYRLSLEADRAKREAHEREMAEQFRLEQIRKEQEEE 549
++++ ++ E + + ++REQ L ++ + E HE++ ++ R +++++EQEE
Sbjct: 396 RREQQLRREQQLRREQQLRREQQLRREQQLRREQ-EEERHEQKHEQERREQRLKREQEER 454
Query: 550 REAIRLSLE----------QALPPEPKEENAEPVSKL 576
R+ ++ E Q L + +EE E KL
Sbjct: 455 RDWLKREEETERHEQERRKQQLKRDQEEERRERWLKL 491
Score = 34.3 bits (77), Expect = 0.37
Identities = 28/81 (34%), Positives = 40/81 (49%), Gaps = 6/81 (7%)
Query: 487 FTAQQQEDIKDEDEREARENVK--REQDEAYRLSLEADRAKRE----AHEREMAEQFRLE 540
F ++Q+ + E ER+ E+ + R Q+ +L E DR RE ERE + R E
Sbjct: 1581 FRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQE 1640
Query: 541 QIRKEQEEEREAIRLSLEQAL 561
+ RK EEE + R EQ L
Sbjct: 1641 RDRKFLEEEPQLRRQEREQQL 1661
Score = 33.9 bits (76), Expect = 0.48
Identities = 32/139 (23%), Positives = 58/139 (41%), Gaps = 29/139 (20%)
Query: 490 QQQEDIKDEDEREARENVKREQDE----------------AYRLSLEADRAKREAHEREM 533
++Q + +E+E+E R +RE+++ A +L E D + + R
Sbjct: 806 REQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRS 865
Query: 534 AEQFRLEQIRKEQEEEREAIRLSL-------------EQALPPEPKEENAEPVSKLRIRT 580
EQ R ++ R + EEER+ R +L +Q L E +E E K R +
Sbjct: 866 QEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQE 925
Query: 581 PSGEFLERRFLASNKLQIV 599
++ E L + Q++
Sbjct: 926 QERQYREEEQLQQEEEQLL 944
Score = 33.9 bits (76), Expect = 0.48
Identities = 17/62 (27%), Positives = 38/62 (61%), Gaps = 1/62 (1%)
Query: 491 QQEDIKDEDEREARENVKREQDEAYRLSLE-ADRAKREAHEREMAEQFRLEQIRKEQEEE 549
++E ++ E+++EA+ ++ Q+E L E ++ +R+ +R+ E+ +L Q R+EQ
Sbjct: 1295 EEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLR 1354
Query: 550 RE 551
R+
Sbjct: 1355 RQ 1356
Score = 33.1 bits (74), Expect = 0.82
Identities = 21/80 (26%), Positives = 38/80 (47%), Gaps = 1/80 (1%)
Query: 490 QQQEDIKDEDEREARENVKREQDEAYRLSLEADRAKREAHEREMAEQFRLEQ-IRKEQEE 548
++QE+ + E + + ++REQ L ++ R + +Q R EQ +R+EQ+
Sbjct: 366 REQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 425
Query: 549 EREAIRLSLEQALPPEPKEE 568
RE EQ E +E+
Sbjct: 426 RREQEEERHEQKHEQERREQ 445
Score = 33.1 bits (74), Expect = 0.82
Identities = 26/118 (22%), Positives = 55/118 (46%), Gaps = 7/118 (5%)
Query: 485 EIFTAQQQEDIKDEDEREARENVKREQDEAYRLSLEADRAKREAHEREMAEQFRLEQ--- 541
++ ++++ E ER+ RE + +Q+E L E + +R+ ER+ ++ L+Q
Sbjct: 1032 QLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEE 1091
Query: 542 --IRKEQEEEREAIRLSLEQALPPEPKEENAEPVSKLRIRTPSGEFLERRFLASNKLQ 597
+R+E E+ R R Q E ++ E + + + LER++ ++Q
Sbjct: 1092 QLLREEPEKRRRQER--ERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQ 1147
Score = 32.7 bits (73), Expect = 1.1
Identities = 26/101 (25%), Positives = 51/101 (50%), Gaps = 3/101 (2%)
Query: 490 QQQEDIKDEDEREARENVKREQDEAYRLSLEADRA-KREAHEREMAEQFRLEQIRKEQEE 548
++Q+ ++++ER + ++E++E + L +++ +RE ER R E+ R EQE
Sbjct: 503 REQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQER 562
Query: 549 EREAIRLSLEQALPPEPKEENAEPVSKLRIRTPSGEFLERR 589
+ RL EQ + + E + R++ E LE+R
Sbjct: 563 REQ--RLKREQEERRDQLLKREEERRQQRLKREQEERLEQR 601
Score = 32.7 bits (73), Expect = 1.1
Identities = 26/96 (27%), Positives = 46/96 (47%), Gaps = 3/96 (3%)
Query: 482 AAMEIFTAQQQEDIKDEDEREARENVKREQDEAYRLSLEADRAKREAHE--REMAEQFRL 539
A E +QQ ++E+E + E KR + E R E ++ ++E + RE E+ R
Sbjct: 894 ALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREK-RR 952
Query: 540 EQIRKEQEEEREAIRLSLEQALPPEPKEENAEPVSK 575
Q R+ Q + + ++ EQ L EP++ + K
Sbjct: 953 RQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREK 988
Score = 32.7 bits (73), Expect = 1.1
Identities = 24/103 (23%), Positives = 49/103 (47%), Gaps = 16/103 (15%)
Query: 485 EIFTAQQQEDIKDEDEREARENVKREQDEAYRLSLEADRAKREAHEREMAEQFRLEQ--- 541
++ ++++ + E ER+ R+ + +Q+E L E ++ + + ER+ E+ L+Q
Sbjct: 1002 QLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEE 1061
Query: 542 --------IRKEQEEER-----EAIRLSLEQALPPEPKEENAE 571
R+ QE ER E ++ EQ L EP++ +
Sbjct: 1062 QLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQ 1104
Score = 32.3 bits (72), Expect = 1.4
Identities = 33/128 (25%), Positives = 61/128 (47%), Gaps = 22/128 (17%)
Query: 490 QQQEDIKDEDEREARENVK-REQDEAYRLSLEADRAKREAHEREMAEQFRLEQIRKEQEE 548
++++++ +E++ +ARE +K R ++L EAD + + + R ++ ++ R+EQEE
Sbjct: 680 RREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEG--QRRRQEQEE 737
Query: 549 EREAIRLSL-----EQALPPEPKEE---------NAEPVS-----KLRIRTPSGEFLERR 589
+R L E+A + +EE AE S +L R P E ER+
Sbjct: 738 KRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQ 797
Query: 590 FLASNKLQ 597
A + Q
Sbjct: 798 LRAEERQQ 805
Score = 32.0 bits (71), Expect = 1.8
Identities = 26/84 (30%), Positives = 45/84 (53%), Gaps = 9/84 (10%)
Query: 490 QQQEDIKDEDEREARENVKREQDEAYRLSLEADRAKREAHEREMAEQFRLEQIRKEQEEE 549
Q + +D RE + ++R++ E L E + +R+ ER+ E+ EQ+R+E E+E
Sbjct: 1683 QLRRQERDRKFREEEQQLRRQERERKFLQ-EEQQLRRQELERKFREE---EQLRQETEQE 1738
Query: 550 ----REAIRLSL-EQALPPEPKEE 568
+E R L E+ L PE +E+
Sbjct: 1739 QLRRQERYRKILEEEQLRPEREEQ 1762
Score = 32.0 bits (71), Expect = 1.8
Identities = 18/77 (23%), Positives = 42/77 (54%), Gaps = 7/77 (9%)
Query: 474 DELMMRLMAAMEIFTAQQQEDIKDEDEREARENVKREQDEAYRLSLEADRAKREAHEREM 533
+E ++L + ++ + E++ +E +RE+ E ++ E ++ +R+ ER++
Sbjct: 1824 EEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQ---EEEQKRRQERERKL 1880
Query: 534 AEQFRLEQIRKEQEEER 550
E E IR++Q+EE+
Sbjct: 1881 RE----EHIRRQQKEEQ 1893
Score = 31.2 bits (69), Expect = 3.1
Identities = 29/103 (28%), Positives = 47/103 (45%), Gaps = 6/103 (5%)
Query: 490 QQQEDIKDEDEREARENVKR-EQDEAYRLSLEADRAKREAHEREMAE---QFRLEQIRKE 545
QQ +D RE + + R E+D +R E + +R+ ER+ E Q R E+ RK
Sbjct: 1406 QQLRQDRDRKFREEEQQLSRQERDRKFRE--EEQQVRRQERERKFLEEEQQLRQERHRKF 1463
Query: 546 QEEEREAIRLSLEQALPPEPKEENAEPVSKLRIRTPSGEFLER 588
+EEE+ +Q E + E +LR + +F E+
Sbjct: 1464 REEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQ 1506
Score = 30.8 bits (68), Expect = 4.1
Identities = 20/80 (25%), Positives = 43/80 (53%), Gaps = 5/80 (6%)
Query: 492 QEDIKDEDEREARENVKREQDEAYRLSLEADRAKREAHEREMAE---QFRLEQIRKEQEE 548
+E+ + ERE ++ ++E+D +R LE + +R+ ER+ E Q R ++ +++ +
Sbjct: 1558 REEEQLRQEREEQQLSRQERDRKFR--LEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQ 1615
Query: 549 EREAIRLSLEQALPPEPKEE 568
ER+ EQ L +++
Sbjct: 1616 ERDRKFREDEQLLQEREEQQ 1635
Score = 30.0 bits (66), Expect = 7.0
Identities = 23/65 (35%), Positives = 32/65 (49%), Gaps = 5/65 (7%)
Query: 490 QQQEDIKDEDEREAREN-VKREQDEAYRLSLEADRAKRE----AHEREMAEQFRLEQIRK 544
++Q++ K D + E + RE+ E R E DR RE ERE R E+ RK
Sbjct: 1302 EEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRK 1361
Query: 545 EQEEE 549
+EEE
Sbjct: 1362 FREEE 1366
Score = 30.0 bits (66), Expect = 7.0
Identities = 17/54 (31%), Positives = 34/54 (62%), Gaps = 3/54 (5%)
Query: 500 EREARENVKREQDEAYR--LSLEADRAKREAHEREMAEQFR-LEQIRKEQEEER 550
ERE ++ ++E+D +R L +R +++ +E +FR EQ+R+E+EE++
Sbjct: 1758 EREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQ 1811
Score = 29.6 bits (65), Expect = 9.1
Identities = 22/73 (30%), Positives = 37/73 (50%), Gaps = 5/73 (6%)
Query: 491 QQEDIKDEDE----REARENVKREQDEAYRLSLEADRAKREAHEREMAEQFRLEQIRKEQ 546
++ D K ++E RE RE KR + E R E ++ +E E+ + Q R + R+E+
Sbjct: 1308 KRRDRKSQEEKQLLREEREE-KRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEE 1366
Query: 547 EEEREAIRLSLEQ 559
+E R LE+
Sbjct: 1367 LRHQEQGRKFLEE 1379
Score = 29.6 bits (65), Expect = 9.1
Identities = 23/105 (21%), Positives = 50/105 (47%), Gaps = 6/105 (5%)
Query: 479 RLMAAMEIFTAQQQEDIKDEDEREARENVKRE--QDEAYRLSLEADRAKREAHEREMAEQ 536
R E+ + + + +E+++ R+ +R+ Q+E E + +R+ +R+ E+
Sbjct: 1501 RKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREE 1560
Query: 537 FRLEQIRKEQEEERE----AIRLSLEQALPPEPKEENAEPVSKLR 577
+L Q R+EQ+ R+ RL ++ E + + E +LR
Sbjct: 1561 EQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLR 1605
>gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo
sapiens]
Length = 956
Score = 48.1 bits (113), Expect = 2e-05
Identities = 29/116 (25%), Positives = 65/116 (56%), Gaps = 7/116 (6%)
Query: 467 IQGNTTVDELMM-----RLMAAMEIFTAQQQEDIKDEDEREARENVKREQDEAYRLSLEA 521
++G+T ++L + RL +++ +++++ E+ + A+E K++++E L +
Sbjct: 326 VKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKE 385
Query: 522 DRAKREAHEREMAEQFRLEQIRKEQEEEREAIRLSLEQALPPEPKEENAEPVSKLR 577
R KRE E+E AE+ RL++ R+ +E +EA+ LE+ E ++ E +++
Sbjct: 386 RREKREKDEKEKAEKQRLKEERR--KERQEALEAKLEEKRKKEEEKRLREEEKRIK 439
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 47.4 bits (111), Expect = 4e-05
Identities = 36/95 (37%), Positives = 52/95 (54%), Gaps = 11/95 (11%)
Query: 485 EIFTAQQQEDIKDEDEREARENVKREQDEAYRLSLEAD---RAKREAHEREMAEQF--RL 539
EI QQ+E+ K RE E +R+Q+EA R E + R +RE ER+ E+ RL
Sbjct: 761 EILRRQQEEERK---RREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRL 817
Query: 540 EQIRKEQEEER---EAIRLSLEQALPPEPKEENAE 571
E+ R+E+EE R E +R E+A +EE A+
Sbjct: 818 EERRREEEERRKQEELLRKQEEEAAKWAREEEEAQ 852
Score = 45.8 bits (107), Expect = 1e-04
Identities = 28/94 (29%), Positives = 55/94 (58%), Gaps = 9/94 (9%)
Query: 496 KDEDEREARENVKREQDEAYRLSLEADRAKREAHEREMAEQFRLEQIRKEQEEEREAIRL 555
++E+ER+ +E ++R+Q+E R E +R +RE E E+A + + E +R+++E+E +
Sbjct: 744 REEEERKRQEELRRQQEEILRRQQEEERKRRE--EEELARRKQEEALRRQREQE-----I 796
Query: 556 SLEQALPPEPKEENAEPVSKLRIRTPSGEFLERR 589
+L + E +++ E + +L R E ERR
Sbjct: 797 ALRRQREEEERQQQEEALRRLEERRREEE--ERR 828
Score = 35.0 bits (79), Expect = 0.22
Identities = 22/115 (19%), Positives = 61/115 (53%), Gaps = 11/115 (9%)
Query: 490 QQQEDI---------KDEDEREARENVKREQDEAYRLSLEADRAKREAHEREMAEQFRLE 540
QQQE+ ++E+ R+ E ++++++EA + + E + A+R E + +
Sbjct: 808 QQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAA 867
Query: 541 QIRKEQEE-EREAIRLSLEQALPPEPKEENAEPVSKLRIRTPSGEFLERRFLASN 594
++R E+EE +R+ + + ++ L + +++ E + +L+ + + + + +S+
Sbjct: 868 RLRHEEEERKRKELEVQRQKELMRQ-RQQQQEALRRLQQQQQQQQLAQMKLPSSS 921
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 47.4 bits (111), Expect = 4e-05
Identities = 36/95 (37%), Positives = 52/95 (54%), Gaps = 11/95 (11%)
Query: 485 EIFTAQQQEDIKDEDEREARENVKREQDEAYRLSLEAD---RAKREAHEREMAEQF--RL 539
EI QQ+E+ K RE E +R+Q+EA R E + R +RE ER+ E+ RL
Sbjct: 788 EILRRQQEEERK---RREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRL 844
Query: 540 EQIRKEQEEER---EAIRLSLEQALPPEPKEENAE 571
E+ R+E+EE R E +R E+A +EE A+
Sbjct: 845 EERRREEEERRKQEELLRKQEEEAAKWAREEEEAQ 879
Score = 45.8 bits (107), Expect = 1e-04
Identities = 28/94 (29%), Positives = 55/94 (58%), Gaps = 9/94 (9%)
Query: 496 KDEDEREARENVKREQDEAYRLSLEADRAKREAHEREMAEQFRLEQIRKEQEEEREAIRL 555
++E+ER+ +E ++R+Q+E R E +R +RE E E+A + + E +R+++E+E +
Sbjct: 771 REEEERKRQEELRRQQEEILRRQQEEERKRRE--EEELARRKQEEALRRQREQE-----I 823
Query: 556 SLEQALPPEPKEENAEPVSKLRIRTPSGEFLERR 589
+L + E +++ E + +L R E ERR
Sbjct: 824 ALRRQREEEERQQQEEALRRLEERRREEE--ERR 855
Score = 35.0 bits (79), Expect = 0.22
Identities = 22/115 (19%), Positives = 61/115 (53%), Gaps = 11/115 (9%)
Query: 490 QQQEDI---------KDEDEREARENVKREQDEAYRLSLEADRAKREAHEREMAEQFRLE 540
QQQE+ ++E+ R+ E ++++++EA + + E + A+R E + +
Sbjct: 835 QQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAA 894
Query: 541 QIRKEQEE-EREAIRLSLEQALPPEPKEENAEPVSKLRIRTPSGEFLERRFLASN 594
++R E+EE +R+ + + ++ L + +++ E + +L+ + + + + +S+
Sbjct: 895 RLRHEEEERKRKELEVQRQKELMRQ-RQQQQEALRRLQQQQQQQQLAQMKLPSSS 948
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 47.4 bits (111), Expect = 4e-05
Identities = 36/95 (37%), Positives = 52/95 (54%), Gaps = 11/95 (11%)
Query: 485 EIFTAQQQEDIKDEDEREARENVKREQDEAYRLSLEAD---RAKREAHEREMAEQF--RL 539
EI QQ+E+ K RE E +R+Q+EA R E + R +RE ER+ E+ RL
Sbjct: 767 EILRRQQEEERK---RREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRL 823
Query: 540 EQIRKEQEEER---EAIRLSLEQALPPEPKEENAE 571
E+ R+E+EE R E +R E+A +EE A+
Sbjct: 824 EERRREEEERRKQEELLRKQEEEAAKWAREEEEAQ 858
Score = 45.8 bits (107), Expect = 1e-04
Identities = 28/94 (29%), Positives = 55/94 (58%), Gaps = 9/94 (9%)
Query: 496 KDEDEREARENVKREQDEAYRLSLEADRAKREAHEREMAEQFRLEQIRKEQEEEREAIRL 555
++E+ER+ +E ++R+Q+E R E +R +RE E E+A + + E +R+++E+E +
Sbjct: 750 REEEERKRQEELRRQQEEILRRQQEEERKRRE--EEELARRKQEEALRRQREQE-----I 802
Query: 556 SLEQALPPEPKEENAEPVSKLRIRTPSGEFLERR 589
+L + E +++ E + +L R E ERR
Sbjct: 803 ALRRQREEEERQQQEEALRRLEERRREEE--ERR 834
Score = 35.0 bits (79), Expect = 0.22
Identities = 22/115 (19%), Positives = 61/115 (53%), Gaps = 11/115 (9%)
Query: 490 QQQEDI---------KDEDEREARENVKREQDEAYRLSLEADRAKREAHEREMAEQFRLE 540
QQQE+ ++E+ R+ E ++++++EA + + E + A+R E + +
Sbjct: 814 QQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAA 873
Query: 541 QIRKEQEE-EREAIRLSLEQALPPEPKEENAEPVSKLRIRTPSGEFLERRFLASN 594
++R E+EE +R+ + + ++ L + +++ E + +L+ + + + + +S+
Sbjct: 874 RLRHEEEERKRKELEVQRQKELMRQ-RQQQQEALRRLQQQQQQQQLAQMKLPSSS 927
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 47.4 bits (111), Expect = 4e-05
Identities = 36/95 (37%), Positives = 52/95 (54%), Gaps = 11/95 (11%)
Query: 485 EIFTAQQQEDIKDEDEREARENVKREQDEAYRLSLEAD---RAKREAHEREMAEQF--RL 539
EI QQ+E+ K RE E +R+Q+EA R E + R +RE ER+ E+ RL
Sbjct: 767 EILRRQQEEERK---RREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRL 823
Query: 540 EQIRKEQEEER---EAIRLSLEQALPPEPKEENAE 571
E+ R+E+EE R E +R E+A +EE A+
Sbjct: 824 EERRREEEERRKQEELLRKQEEEAAKWAREEEEAQ 858
Score = 45.8 bits (107), Expect = 1e-04
Identities = 28/94 (29%), Positives = 55/94 (58%), Gaps = 9/94 (9%)
Query: 496 KDEDEREARENVKREQDEAYRLSLEADRAKREAHEREMAEQFRLEQIRKEQEEEREAIRL 555
++E+ER+ +E ++R+Q+E R E +R +RE E E+A + + E +R+++E+E +
Sbjct: 750 REEEERKRQEELRRQQEEILRRQQEEERKRRE--EEELARRKQEEALRRQREQE-----I 802
Query: 556 SLEQALPPEPKEENAEPVSKLRIRTPSGEFLERR 589
+L + E +++ E + +L R E ERR
Sbjct: 803 ALRRQREEEERQQQEEALRRLEERRREEE--ERR 834
Score = 35.0 bits (79), Expect = 0.22
Identities = 22/115 (19%), Positives = 61/115 (53%), Gaps = 11/115 (9%)
Query: 490 QQQEDI---------KDEDEREARENVKREQDEAYRLSLEADRAKREAHEREMAEQFRLE 540
QQQE+ ++E+ R+ E ++++++EA + + E + A+R E + +
Sbjct: 814 QQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAA 873
Query: 541 QIRKEQEE-EREAIRLSLEQALPPEPKEENAEPVSKLRIRTPSGEFLERRFLASN 594
++R E+EE +R+ + + ++ L + +++ E + +L+ + + + + +S+
Sbjct: 874 RLRHEEEERKRKELEVQRQKELMRQ-RQQQQEALRRLQQQQQQQQLAQMKLPSSS 927
>gi|62244004 modulator of estrogen induced transcription isoform b
[Homo sapiens]
Length = 1016
Score = 44.3 bits (103), Expect = 4e-04
Identities = 34/87 (39%), Positives = 54/87 (62%), Gaps = 10/87 (11%)
Query: 479 RLMAAMEIFTAQQQEDIKDEDEREARENVK--REQDEAYRLSLEADRAK--REAHEREMA 534
RL AME+ +++ +I + + RE RE ++ RE++E RL E +R + R+ ERE
Sbjct: 606 RLRRAMEL---RRRREIAERERRE-RERIRIIREREERERLQRERERLEIERQKLERERM 661
Query: 535 EQFRL--EQIRKEQEEEREAIRLSLEQ 559
E+ RL E+IR EQE +EA R++ E+
Sbjct: 662 ERERLERERIRIEQERRKEAERIARER 688
Score = 33.9 bits (76), Expect = 0.48
Identities = 22/68 (32%), Positives = 41/68 (60%), Gaps = 4/68 (5%)
Query: 490 QQQEDIKDEDEREARENVKREQDEAYRLSLEADR---AKREAHEREMAEQFRLEQIRKEQ 546
+++E ++ E ++ RE ++RE+ E R+ +E +R A+R A ERE + + +Q+R EQ
Sbjct: 644 RERERLEIERQKLERERMERERLERERIRIEQERRKEAERIAREREELRR-QQQQLRYEQ 702
Query: 547 EEEREAIR 554
E+ R
Sbjct: 703 EKRNSLKR 710
>gi|63176611 modulator of estrogen induced transcription isoform a
[Homo sapiens]
Length = 1034
Score = 44.3 bits (103), Expect = 4e-04
Identities = 34/87 (39%), Positives = 54/87 (62%), Gaps = 10/87 (11%)
Query: 479 RLMAAMEIFTAQQQEDIKDEDEREARENVK--REQDEAYRLSLEADRAK--REAHEREMA 534
RL AME+ +++ +I + + RE RE ++ RE++E RL E +R + R+ ERE
Sbjct: 624 RLRRAMEL---RRRREIAERERRE-RERIRIIREREERERLQRERERLEIERQKLERERM 679
Query: 535 EQFRL--EQIRKEQEEEREAIRLSLEQ 559
E+ RL E+IR EQE +EA R++ E+
Sbjct: 680 ERERLERERIRIEQERRKEAERIARER 706
Score = 33.9 bits (76), Expect = 0.48
Identities = 22/68 (32%), Positives = 41/68 (60%), Gaps = 4/68 (5%)
Query: 490 QQQEDIKDEDEREARENVKREQDEAYRLSLEADR---AKREAHEREMAEQFRLEQIRKEQ 546
+++E ++ E ++ RE ++RE+ E R+ +E +R A+R A ERE + + +Q+R EQ
Sbjct: 662 RERERLEIERQKLERERMERERLERERIRIEQERRKEAERIAREREELRR-QQQQLRYEQ 720
Query: 547 EEEREAIR 554
E+ R
Sbjct: 721 EKRNSLKR 728
>gi|13376854 UBX domain protein 6 [Homo sapiens]
Length = 441
Score = 43.5 bits (101), Expect = 6e-04
Identities = 49/182 (26%), Positives = 81/182 (44%), Gaps = 25/182 (13%)
Query: 486 IFTAQQQED-----IKDEDEREARENVKREQDE---AYRLSLEADRAKREAHEREMAEQF 537
+ AQ QED + E ++++R +++ A + + DR +R +A QF
Sbjct: 227 LLPAQDQEDPEEFYVLSETTLAQPQSLERHKEQLLAAEPVRAKLDRQRRVFQPSPLASQF 286
Query: 538 RL---------EQIRKEQEEEREAI-RLSLEQALPPEPKEENAE----PVSKLRIRTPSG 583
L E+I++EQ EA+ RLS+ + KEE + LR+R P G
Sbjct: 287 ELPGDFFNLTAEEIKREQRLRSEAVERLSVLRTKAMREKEEQRGLRKYNYTLLRVRLPDG 346
Query: 584 EFLERRFLASNKLQIVFDFV-ASKGFPWDEYKLLSTFPRRDVTQLDPNKSLLEVKLFPQE 642
L+ F A +L V+ FV + W ++LL++ ++ D N +L E L P
Sbjct: 347 CLLQGTFYARERLGAVYGFVREALQSDWLPFELLASGGQK--LSEDENLALNECGLVPSA 404
Query: 643 TL 644
L
Sbjct: 405 LL 406
>gi|4557543 extracellular matrix protein 2 precursor [Homo sapiens]
Length = 699
Score = 43.5 bits (101), Expect = 6e-04
Identities = 35/124 (28%), Positives = 58/124 (46%), Gaps = 10/124 (8%)
Query: 462 EVLNVIQGNTTVDELMMRLMAAMEIFTAQQQEDIKDEDEREARENVK-REQDEAYRL--S 518
E N++ ++ M + E +++ E++K+ED + RE + R Q + Y S
Sbjct: 186 EPTNLLHKQLPPPQVGMDRIVRKEALQSEEDEEVKEEDTEQKRETPESRNQGQLYSEGDS 245
Query: 519 LEADRAKREAHEREMAEQFRLEQIRKEQEEEREAIRLSLEQALPPEPKEENAEPVSKLRI 578
DR +R ER +A Q + Q R+E+E+E E E E +E+ +PV
Sbjct: 246 RGGDRKQRPGEERRLAHQ-QQRQGREEEEDEEE------EGEEGEEDEEDEEDPVRGDMF 298
Query: 579 RTPS 582
R PS
Sbjct: 299 RMPS 302
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 42.7 bits (99), Expect = 0.001
Identities = 31/108 (28%), Positives = 48/108 (44%), Gaps = 12/108 (11%)
Query: 481 MAAMEIFTAQQQEDIKDEDEREARENVKREQD-EAYRLSLEADRAKREAHEREMAEQFRL 539
+ + I ++ ++E+ ++E+E E E + E+D E E + E E E E+F
Sbjct: 878 LTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEE 937
Query: 540 EQIRKEQEEEREAIRLSLEQALPPEPKEENAEPVSKLRIRTPSGEFLE 587
E+ E+EEE E E +EE E V L T GE E
Sbjct: 938 EEGELEEEEEEE-----------DEEEEEELEEVEDLEFGTAGGEVEE 974
>gi|92859701 myosin VI [Homo sapiens]
Length = 1285
Score = 42.7 bits (99), Expect = 0.001
Identities = 36/136 (26%), Positives = 66/136 (48%), Gaps = 21/136 (15%)
Query: 436 VAQTIRTQKTDQFPLFLIIMGKRSSNEVLNVIQGNTTVDELMMRLMAAMEIFTAQQQEDI 495
+ T+ TQ+ Q ++ +SS E+L+ +Q +E RL Q+E
Sbjct: 885 IKSTMMTQEQIQKEYDALV---KSSEELLSALQKKKQQEEEAERLRRI-------QEEME 934
Query: 496 KDEDEREARENVKREQDEAYRLSLEADRAKREAHEREMAEQFRLEQIRKEQEEEREAIRL 555
K+ RE E +R+++E R+ LE + AKR+ E E RK++E++ + I+
Sbjct: 935 KERKRREEDEKRRRKEEEERRMKLEME-AKRKQEEEE----------RKKREDDEKRIQA 983
Query: 556 SLEQALPPEPKEENAE 571
+E L + +EE+ +
Sbjct: 984 EVEAQLARQKEEESQQ 999
Score = 37.7 bits (86), Expect = 0.033
Identities = 43/175 (24%), Positives = 83/175 (47%), Gaps = 15/175 (8%)
Query: 433 GSVVAQTIRTQKTDQFPLFLIIM--GKRSSNEVLNVIQGNTTVDELMMRLMAAMEIFTAQ 490
G V T++ ++ D+F + ++ GK N+ + ++ ++D LM ++ + M
Sbjct: 839 GLVKVGTLK-KRLDKFNEVVSVLKDGKPEMNKQIKNLE--ISIDTLMAKIKSTMMTQEQI 895
Query: 491 QQED---IKDEDER-EARENVKREQDEAYRLSLEADRAKREAHEREMAEQFRLEQIRKEQ 546
Q+E +K +E A + K++++EA RL + ++E RE E+ R RKE+
Sbjct: 896 QKEYDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRR----RKEE 951
Query: 547 EEEREAIRLSLEQALPPEPKEENAEPVSKLRIRTPSGEFLERRFLASNKLQIVFD 601
EE R ++L +E E +E + RI+ L R+ ++ Q V +
Sbjct: 952 EERR--MKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKEEESQQQAVLE 1004
>gi|147903302 MAP7 domain containing 3 [Homo sapiens]
Length = 876
Score = 42.4 bits (98), Expect = 0.001
Identities = 33/107 (30%), Positives = 49/107 (45%), Gaps = 10/107 (9%)
Query: 492 QEDIKDEDEREARENVKREQDEAYRLS-LEADRAKREAHEREMAEQFRLEQIRKEQEEER 550
+ DIK RE RE +R+QD LE +R + +E++M E+ R + RKE+EE+R
Sbjct: 64 KNDIKQRLARERREEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKERKEKEEQR 123
Query: 551 EAIRLSLEQALPPEPKEENAEPVSKLRIRTPSGEFLERRFLASNKLQ 597
+ E K + K + LERR LA + Q
Sbjct: 124 R---------IAAEEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQ 161
>gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4
isoform 3 [Homo sapiens]
Length = 1212
Score = 42.0 bits (97), Expect = 0.002
Identities = 30/109 (27%), Positives = 52/109 (47%), Gaps = 27/109 (24%)
Query: 490 QQQEDIKDEDEREARENVKREQDEAYRLSLEADRAKREAHEREMAEQFR------LEQIR 543
+QQ ++ ++ RE +REQ+E RL E +R ++E ER AE+ + E IR
Sbjct: 411 EQQRREREARRQQEREQRRREQEEKRRLE-ELERRRKEEEERRRAEEEKRRVEREQEYIR 469
Query: 544 KEQEEEREAIRLSLEQAL--------------------PPEPKEENAEP 572
++ EEE+ + + +Q L PP P++E ++P
Sbjct: 470 RQLEEEQRHLEVLQQQLLQEQAMLLHDHRRPHPQHSQQPPPPQQERSKP 518
Score = 37.7 bits (86), Expect = 0.033
Identities = 27/82 (32%), Positives = 40/82 (48%), Gaps = 15/82 (18%)
Query: 474 DELMMRLMAAMEIFTAQQQEDIKDEDEREARENVKREQDEAYRLSLEADRAKREAHEREM 533
+E +L+A + QQ+E + +E++ RE R Q E RE RE
Sbjct: 385 EEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQE------------REQRRREQ 432
Query: 534 AEQFRLEQI---RKEQEEEREA 552
E+ RLE++ RKE+EE R A
Sbjct: 433 EEKRRLEELERRRKEEEERRRA 454
Score = 35.0 bits (79), Expect = 0.22
Identities = 33/116 (28%), Positives = 50/116 (43%), Gaps = 22/116 (18%)
Query: 492 QEDIKDEDEREARENVKREQD----EAYRLSLEADRAKR--------------EAHEREM 533
Q++ K+ E R+ + +EQ E Y+ L A+R KR + ERE
Sbjct: 360 QQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREA 419
Query: 534 AEQFRLEQIRKEQEEEREAIRLSLEQALPPEPKEENAEPVSKLRIRTPSGEFLERR 589
Q EQ R+EQEE+R RL + E +E K R+ E++ R+
Sbjct: 420 RRQQEREQRRREQEEKR---RLEELERRRKEEEERRRAEEEKRRVEREQ-EYIRRQ 471
Score = 32.0 bits (71), Expect = 1.8
Identities = 25/92 (27%), Positives = 42/92 (45%), Gaps = 10/92 (10%)
Query: 490 QQQEDIKDEDEREARENVKR----------EQDEAYRLSLEADRAKREAHEREMAEQFRL 539
++Q+ ++++ RE E ++ +Q E R E R +REA ++ EQ R
Sbjct: 371 RRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRR 430
Query: 540 EQIRKEQEEEREAIRLSLEQALPPEPKEENAE 571
EQ K + EE E R E+ E ++ E
Sbjct: 431 EQEEKRRLEELERRRKEEEERRRAEEEKRRVE 462
>gi|22035602 mitogen-activated protein kinase kinase kinase kinase 4
isoform 1 [Homo sapiens]
Length = 1166
Score = 42.0 bits (97), Expect = 0.002
Identities = 30/109 (27%), Positives = 52/109 (47%), Gaps = 27/109 (24%)
Query: 490 QQQEDIKDEDEREARENVKREQDEAYRLSLEADRAKREAHEREMAEQFR------LEQIR 543
+QQ ++ ++ RE +REQ+E RL E +R ++E ER AE+ + E IR
Sbjct: 411 EQQRREREARRQQEREQRRREQEEKRRLE-ELERRRKEEEERRRAEEEKRRVEREQEYIR 469
Query: 544 KEQEEEREAIRLSLEQAL--------------------PPEPKEENAEP 572
++ EEE+ + + +Q L PP P++E ++P
Sbjct: 470 RQLEEEQRHLEVLQQQLLQEQAMLLHDHRRPHPQHSQQPPPPQQERSKP 518
Score = 37.7 bits (86), Expect = 0.033
Identities = 27/82 (32%), Positives = 40/82 (48%), Gaps = 15/82 (18%)
Query: 474 DELMMRLMAAMEIFTAQQQEDIKDEDEREARENVKREQDEAYRLSLEADRAKREAHEREM 533
+E +L+A + QQ+E + +E++ RE R Q E RE RE
Sbjct: 385 EEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQE------------REQRRREQ 432
Query: 534 AEQFRLEQI---RKEQEEEREA 552
E+ RLE++ RKE+EE R A
Sbjct: 433 EEKRRLEELERRRKEEEERRRA 454
Score = 35.0 bits (79), Expect = 0.22
Identities = 33/116 (28%), Positives = 50/116 (43%), Gaps = 22/116 (18%)
Query: 492 QEDIKDEDEREARENVKREQD----EAYRLSLEADRAKR--------------EAHEREM 533
Q++ K+ E R+ + +EQ E Y+ L A+R KR + ERE
Sbjct: 360 QQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREA 419
Query: 534 AEQFRLEQIRKEQEEEREAIRLSLEQALPPEPKEENAEPVSKLRIRTPSGEFLERR 589
Q EQ R+EQEE+R RL + E +E K R+ E++ R+
Sbjct: 420 RRQQEREQRRREQEEKR---RLEELERRRKEEEERRRAEEEKRRVEREQ-EYIRRQ 471
Score = 32.0 bits (71), Expect = 1.8
Identities = 25/92 (27%), Positives = 42/92 (45%), Gaps = 10/92 (10%)
Query: 490 QQQEDIKDEDEREARENVKR----------EQDEAYRLSLEADRAKREAHEREMAEQFRL 539
++Q+ ++++ RE E ++ +Q E R E R +REA ++ EQ R
Sbjct: 371 RRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRR 430
Query: 540 EQIRKEQEEEREAIRLSLEQALPPEPKEENAE 571
EQ K + EE E R E+ E ++ E
Sbjct: 431 EQEEKRRLEELERRRKEEEERRRAEEEKRRVE 462
>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
Length = 732
Score = 42.0 bits (97), Expect = 0.002
Identities = 28/119 (23%), Positives = 59/119 (49%), Gaps = 1/119 (0%)
Query: 479 RLMAAMEIFTAQQQEDIKDEDEREARENVKREQDEAYRLSLEADRAKREAHEREMAEQFR 538
R A ++ +Q+ K+E +R RE +KR+ +E RL LE + K+E + E+ +
Sbjct: 408 RRQARLQKEQEEQERVEKEEQDRLEREELKRKAEEE-RLRLEEEARKQEEERKRQEEEKK 466
Query: 539 LEQIRKEQEEEREAIRLSLEQALPPEPKEENAEPVSKLRIRTPSGEFLERRFLASNKLQ 597
++ ++++ EA R + E+ L E +E+ + + + + + E R +L+
Sbjct: 467 KQEGEEKRKAGEEAKRKAEEELLLKEKQEQEKQEKAMIEKQKEAAETKAREVAEQMRLE 525
Score = 40.8 bits (94), Expect = 0.004
Identities = 35/143 (24%), Positives = 69/143 (48%), Gaps = 14/143 (9%)
Query: 441 RTQKTDQFPLFLIIMGKRSSNEVLNVIQGNTTVDELMMRLMAAMEIFTAQQQEDIKDEDE 500
R +K +Q L + +++ E L + + +E R + +++ +E +
Sbjct: 422 RVEKEEQDRLEREELKRKAEEERLRLEEEARKQEEERKRQEEEKKKQEGEEKRKAGEEAK 481
Query: 501 REARENV----KREQDEAYRLSLEADRAKREAHEREMAEQFRLE--QIRKEQEEER---- 550
R+A E + K+EQ++ + +E + E RE+AEQ RLE QI + E+ER
Sbjct: 482 RKAEEELLLKEKQEQEKQEKAMIEKQKEAAETKAREVAEQMRLEREQIMLQIEQERLERK 541
Query: 551 ----EAIRLSLEQALPPEPKEEN 569
E ++ + + +PP+ K+E+
Sbjct: 542 KRIDEIMKRTRKSDVPPQVKKED 564
Score = 36.6 bits (83), Expect = 0.074
Identities = 21/63 (33%), Positives = 39/63 (61%), Gaps = 8/63 (12%)
Query: 489 AQQQEDIKDEDEREARENVKREQDEAYRLSLEADRAKREAHEREMAEQFRLEQIRKEQEE 548
A+++ + + E+E +E V++E+ + LE + KR+A E E+ RLE+ ++QEE
Sbjct: 405 AEKRRQARLQKEQEEQERVEKEEQDR----LEREELKRKAEE----ERLRLEEEARKQEE 456
Query: 549 ERE 551
ER+
Sbjct: 457 ERK 459
Score = 35.0 bits (79), Expect = 0.22
Identities = 22/71 (30%), Positives = 41/71 (57%), Gaps = 2/71 (2%)
Query: 498 EDEREARENVKREQDEAYRLSLEADRAKREAHEREMAEQFRLEQIRKEQEEEREAIRLSL 557
E ++ AR +++ +E +R LE R +RE +R E+ R +++R+E+E +R SL
Sbjct: 78 EKQKRARLQYEKQMEERWR-KLEEQR-QREDQKRAAVEEKRKQKLREEEERLEAMMRRSL 135
Query: 558 EQALPPEPKEE 568
E+ E K++
Sbjct: 136 ERTQQLELKKK 146
Score = 34.7 bits (78), Expect = 0.28
Identities = 27/110 (24%), Positives = 53/110 (48%), Gaps = 8/110 (7%)
Query: 487 FTAQQQEDIKDEDEREARENVKREQDEAYRLS-----LEADRAKREAHEREMAEQFR-LE 540
+ Q E DER+ +RE+ E + LE + R +E++M E++R LE
Sbjct: 40 YRPQGMEGFLKSDERQRLAKERREEREKCLAAREQQILEKQKRARLQYEKQMEERWRKLE 99
Query: 541 QIRKEQEEEREAIRLSLEQALPPEPKEENAEPVSKLRIRTPSGEFLERRF 590
+ R+ ++++R A+ +Q L E EE E + + + L++++
Sbjct: 100 EQRQREDQKRAAVEEKRKQKLREE--EERLEAMMRRSLERTQQLELKKKY 147
>gi|4505101 microtubule-associated protein 7 [Homo sapiens]
Length = 749
Score = 41.6 bits (96), Expect = 0.002
Identities = 32/102 (31%), Positives = 51/102 (50%), Gaps = 4/102 (3%)
Query: 471 TTVDELMMRLMAAMEIFTAQQQEDIKDEDEREARENVKREQDE--AYRLSLEADRAKREA 528
TT E RL+A +Q+E K+E ER +E ++R++ E A R++ E + E
Sbjct: 473 TTDPEEATRLLAEKRRLAREQRE--KEERERREQEELERQKREELAQRVAEERTTRREEE 530
Query: 529 HEREMAEQFRLEQIRKEQEEEREAIRLSLEQALPPEPKEENA 570
R AEQ R ++ + +++ E A+R E KEE A
Sbjct: 531 SRRLEAEQAREKEEQLQRQAEERALREREEAERAQRQKEEEA 572
Score = 38.1 bits (87), Expect = 0.026
Identities = 22/65 (33%), Positives = 38/65 (58%), Gaps = 3/65 (4%)
Query: 489 AQQQEDIKDEDEREARENVKREQDEAYRLSLEADRAKREAHEREMAEQFRLEQIRKEQEE 548
A+Q + +++ +R+A E RE++EA R + + EA RE AE+ R E+ + Q E
Sbjct: 536 AEQAREKEEQLQRQAEERALREREEAERAQRQKE---EEARVREEAERVRQEREKHFQRE 592
Query: 549 EREAI 553
E+E +
Sbjct: 593 EQERL 597
Score = 35.8 bits (81), Expect = 0.13
Identities = 27/103 (26%), Positives = 52/103 (50%), Gaps = 5/103 (4%)
Query: 489 AQQQEDIKDEDEREARENVKREQDEAYRLSLEADRAKREAHEREMAEQFRLEQIRKEQEE 548
A+++ ++E+ R RE++E + E +RA RE E E A++ + E+ R +E
Sbjct: 520 AEERTTRREEESRRLEAEQAREKEEQLQRQAE-ERALREREEAERAQRQKEEEARVREEA 578
Query: 549 EREAIRLSLEQALPPEPKE--ENAEPVSKLRIRTPSGEFLERR 589
ER +R E+ E +E E + + ++ RT E +++
Sbjct: 579 ER--VRQEREKHFQREEQERLERKKRLEEIMKRTRRTEATDKK 619
Score = 31.6 bits (70), Expect = 2.4
Identities = 24/78 (30%), Positives = 42/78 (53%), Gaps = 4/78 (5%)
Query: 497 DEDEREAREN-VKREQDEAYR--LSLEADRAKREAHEREMAEQF-RLEQIRKEQEEEREA 552
D+ +R ARE +RE+ A R + LE + R+ +E+ + E+ RLE+ R+++E R A
Sbjct: 64 DDRQRLARERREEREKQLAAREIVWLEREERARQHYEKHLEERKKRLEEQRQKEERRRAA 123
Query: 553 IRLSLEQALPPEPKEENA 570
+ Q L + + A
Sbjct: 124 VEEKRRQRLEEDKERHEA 141
>gi|15826852 acyl-Coenzyme A binding domain containing 3 [Homo
sapiens]
Length = 528
Score = 41.2 bits (95), Expect = 0.003
Identities = 27/89 (30%), Positives = 50/89 (56%), Gaps = 6/89 (6%)
Query: 476 LMMRLMAAMEIFTAQQQEDIKDEDEREARENVKRE---QDEAYRLSLEADRAKREAHERE 532
L +A+ +I +Q++ K+E+ER RE +RE ++E R E +R +RE ER
Sbjct: 171 LFSTYVASHKIEKEEQEKKRKEEEERRRREEEERERLQKEEEKRRREEEERLRREEEERR 230
Query: 533 MAEQFRLEQIRKEQEEEREAIRLSLEQAL 561
E+ E++R EQ++++ L+ + A+
Sbjct: 231 RIEE---ERLRLEQQKQQIMAALNSQTAV 256
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 40.8 bits (94), Expect = 0.004
Identities = 38/150 (25%), Positives = 70/150 (46%), Gaps = 10/150 (6%)
Query: 457 KRSSNEVLNVIQGNTTVDELMMRLMAAMEIFTAQQQEDIKDEDEREARENVKREQDEAYR 516
K+++ + + ++ +E RL + ++ +++ + + E +E + R+ EA R
Sbjct: 625 KKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERL-RKAAEAKR 683
Query: 517 LS--LEADRAKREAHEREMAEQFRLEQIRKEQEEE-------REAIRLSLEQALPPEPKE 567
L+ E +R ++E E+E EQ R EQ R+EQE + RE RL E+ L K
Sbjct: 684 LAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKA 743
Query: 568 ENAEPVSKLRIRTPSGEFLERRFLASNKLQ 597
+ R + E++ LA +LQ
Sbjct: 744 LRLQKEQLQRELEEKKKKEEQQRLAERQLQ 773
Score = 40.4 bits (93), Expect = 0.005
Identities = 37/131 (28%), Positives = 63/131 (48%), Gaps = 7/131 (5%)
Query: 474 DELMMRLMAAMEIFTAQQQEDIKDEDEREARENVKREQDEAYRLSLEADRAKREAHEREM 533
+E RL A E +Q + ++ E+E RE +REQ+ + E +R E R
Sbjct: 669 EEEQERLRKAAEAKRLAEQRE-QERREQERREQERREQERREQERREQERQLAEQERRR- 726
Query: 534 AEQFRLEQIRKEQEEEREAIRLSLEQ---ALPPEPKEENAEPVSKLRIRTPSGEFLERRF 590
EQ RL+ R+ QE E+ A+RL EQ L + K+E + +++ +++ + +
Sbjct: 727 -EQERLQAERELQEREK-ALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAA 784
Query: 591 LASNKLQIVFD 601
AS L + D
Sbjct: 785 GASKALNVTVD 795
Score = 36.6 bits (83), Expect = 0.074
Identities = 37/140 (26%), Positives = 63/140 (45%), Gaps = 8/140 (5%)
Query: 437 AQTIRTQKTDQFPLFLIIMGKRSSNEVLN-VIQGNTTVDELMMRLMAAMEIFTAQQQEDI 495
A+ +R QK ++ + K E L V+Q V+++ +E AQ E
Sbjct: 551 AEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKT 610
Query: 496 -KDEDEREARENVKREQDEAYRLSLEADRAKREAHER------EMAEQFRLEQIRKEQEE 548
K ++ER A E K++ +EA R + E R E E+ E ++K++EE
Sbjct: 611 EKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEE 670
Query: 549 EREAIRLSLEQALPPEPKEE 568
E+E +R + E E +E+
Sbjct: 671 EQERLRKAAEAKRLAEQREQ 690
Score = 35.4 bits (80), Expect = 0.17
Identities = 26/101 (25%), Positives = 54/101 (53%), Gaps = 3/101 (2%)
Query: 490 QQQEDIKDEDEREARENVKREQDEAYRLSLEADRAKREAHEREMAE-QFRLEQIRKEQEE 548
Q+ E+++ ++E E K E+D+ RL E + KRE R++ + + R+EQ+++E+++
Sbjct: 540 QRLENLRRKEEAEQLRRQKVEEDKRRRL--EEVKLKREERLRKVLQARERVEQMKEEKKK 597
Query: 549 EREAIRLSLEQALPPEPKEENAEPVSKLRIRTPSGEFLERR 589
+ E +++ +E AE +K + E +E R
Sbjct: 598 QIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEAR 638
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 40.8 bits (94), Expect = 0.004
Identities = 38/150 (25%), Positives = 70/150 (46%), Gaps = 10/150 (6%)
Query: 457 KRSSNEVLNVIQGNTTVDELMMRLMAAMEIFTAQQQEDIKDEDEREARENVKREQDEAYR 516
K+++ + + ++ +E RL + ++ +++ + + E +E + R+ EA R
Sbjct: 621 KKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERL-RKAAEAKR 679
Query: 517 LS--LEADRAKREAHEREMAEQFRLEQIRKEQEEE-------REAIRLSLEQALPPEPKE 567
L+ E +R ++E E+E EQ R EQ R+EQE + RE RL E+ L K
Sbjct: 680 LAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKA 739
Query: 568 ENAEPVSKLRIRTPSGEFLERRFLASNKLQ 597
+ R + E++ LA +LQ
Sbjct: 740 LRLQKEQLQRELEEKKKKEEQQRLAERQLQ 769
Score = 40.4 bits (93), Expect = 0.005
Identities = 37/131 (28%), Positives = 63/131 (48%), Gaps = 7/131 (5%)
Query: 474 DELMMRLMAAMEIFTAQQQEDIKDEDEREARENVKREQDEAYRLSLEADRAKREAHEREM 533
+E RL A E +Q + ++ E+E RE +REQ+ + E +R E R
Sbjct: 665 EEEQERLRKAAEAKRLAEQRE-QERREQERREQERREQERREQERREQERQLAEQERRR- 722
Query: 534 AEQFRLEQIRKEQEEEREAIRLSLEQ---ALPPEPKEENAEPVSKLRIRTPSGEFLERRF 590
EQ RL+ R+ QE E+ A+RL EQ L + K+E + +++ +++ + +
Sbjct: 723 -EQERLQAERELQEREK-ALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAA 780
Query: 591 LASNKLQIVFD 601
AS L + D
Sbjct: 781 GASKALNVTVD 791
Score = 36.6 bits (83), Expect = 0.074
Identities = 37/140 (26%), Positives = 63/140 (45%), Gaps = 8/140 (5%)
Query: 437 AQTIRTQKTDQFPLFLIIMGKRSSNEVLN-VIQGNTTVDELMMRLMAAMEIFTAQQQEDI 495
A+ +R QK ++ + K E L V+Q V+++ +E AQ E
Sbjct: 547 AEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKT 606
Query: 496 -KDEDEREARENVKREQDEAYRLSLEADRAKREAHER------EMAEQFRLEQIRKEQEE 548
K ++ER A E K++ +EA R + E R E E+ E ++K++EE
Sbjct: 607 EKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEE 666
Query: 549 EREAIRLSLEQALPPEPKEE 568
E+E +R + E E +E+
Sbjct: 667 EQERLRKAAEAKRLAEQREQ 686
Score = 35.4 bits (80), Expect = 0.17
Identities = 26/101 (25%), Positives = 54/101 (53%), Gaps = 3/101 (2%)
Query: 490 QQQEDIKDEDEREARENVKREQDEAYRLSLEADRAKREAHEREMAE-QFRLEQIRKEQEE 548
Q+ E+++ ++E E K E+D+ RL E + KRE R++ + + R+EQ+++E+++
Sbjct: 536 QRLENLRRKEEAEQLRRQKVEEDKRRRL--EEVKLKREERLRKVLQARERVEQMKEEKKK 593
Query: 549 EREAIRLSLEQALPPEPKEENAEPVSKLRIRTPSGEFLERR 589
+ E +++ +E AE +K + E +E R
Sbjct: 594 QIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEAR 634
>gi|27734911 DAZ interacting protein 1-like [Homo sapiens]
Length = 767
Score = 40.8 bits (94), Expect = 0.004
Identities = 41/142 (28%), Positives = 69/142 (48%), Gaps = 19/142 (13%)
Query: 461 NEVLNVIQGNTTVDELMMRLMA--AMEIFTAQQQEDIKDEDEREARE-NVKREQDEAYRL 517
+E NV + N+T++E + L + ME +++ +E R+ARE RE+ E +
Sbjct: 276 DEFKNVAKQNSTLEEKLRALQSHSVMESKLGSLRDEESEEWLRQARELQALREKTEIQKT 335
Query: 518 SLEADRAKREAHEREMAEQFRLEQIRKEQEEEREAIRLSLEQALPPEPKEENAEPVSKLR 577
E R +E HE MAE +KE +EE + ++ SL Q ++ A S+ +
Sbjct: 336 --EWKRKVKELHEEHMAE-------KKELQEENQRLQASLSQ------DQKKAAAQSQCQ 380
Query: 578 IRTPSGEFLER-RFLASNKLQI 598
I T + E+ R +AS + I
Sbjct: 381 ISTLRAQLQEQARIIASQEEMI 402
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.131 0.375
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,629,834
Number of Sequences: 37866
Number of extensions: 1089202
Number of successful extensions: 10591
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 160
Number of HSP's successfully gapped in prelim test: 365
Number of HSP's that attempted gapping in prelim test: 6954
Number of HSP's gapped (non-prelim): 2696
length of query: 650
length of database: 18,247,518
effective HSP length: 109
effective length of query: 541
effective length of database: 14,120,124
effective search space: 7638987084
effective search space used: 7638987084
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.