Search of human proteins with 58761484

Search of human proteins with 58761484

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|58761484 chaperonin containing TCP1, subunit 3 isoform c
[Homo sapiens]
         (507 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|58761484 chaperonin containing TCP1, subunit 3 isoform c [Hom...   991   0.0  
gi|63162572 chaperonin containing TCP1, subunit 3 isoform a [Hom...   972   0.0  
gi|58761486 chaperonin containing TCP1, subunit 3 isoform b [Hom...   966   0.0  
gi|24307939 chaperonin containing TCP1, subunit 5 (epsilon) [Hom...   258   1e-68
gi|38455427 chaperonin containing TCP1, subunit 4 (delta) [Homo ...   254   1e-67
gi|5453607 chaperonin containing TCP1, subunit 7 isoform a [Homo...   245   8e-65
gi|57863257 T-complex protein 1 isoform a [Homo sapiens]              239   3e-63
gi|4502643 chaperonin containing TCP1, subunit 6A isoform a [Hom...   224   2e-58
gi|58331173 chaperonin containing TCP1, subunit 6B [Homo sapiens]     219   5e-57
gi|5453603 chaperonin containing TCP1, subunit 2 [Homo sapiens]       196   4e-50
gi|48762932 chaperonin containing TCP1, subunit 8 (theta) [Homo ...   182   5e-46
gi|58331171 chaperonin containing TCP1, subunit 6A isoform b [Ho...   181   1e-45
gi|57863259 T-complex protein 1 isoform b [Homo sapiens]              167   2e-41
gi|58331185 chaperonin containing TCP1, subunit 7 isoform b [Hom...   163   3e-40
gi|7657253 T-complex protein 1 [Homo sapiens]                         127   2e-29
gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III ...    99   1e-20
gi|9055272 McKusick-Kaufman syndrome protein [Homo sapiens]            56   7e-08
gi|25914754 McKusick-Kaufman syndrome protein [Homo sapiens]           56   7e-08
gi|41399285 chaperonin [Homo sapiens]                                  45   1e-04
gi|31542947 chaperonin [Homo sapiens]                                  45   1e-04
gi|40217788 Bardet-Biedl syndrome 12 [Homo sapiens]                    35   0.21 
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ...    32   1.4  
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ...    32   1.4  
gi|14251207 MOV10-like 1 [Homo sapiens]                                32   1.8  
gi|23503243 Ras association (RalGDS/AF-6) domain family (N-termi...    32   1.8  
gi|10190716 spindle pole body component 25 [Homo sapiens]              32   1.8  
gi|11968182 ribosomal protein S18 [Homo sapiens]                       31   2.3  
gi|224593271 intermediate filament tail domain containing 1 isof...    31   3.0  
gi|26667191 calcium/calmodulin-dependent protein kinase II gamma...    30   4.0  

>gi|58761484 chaperonin containing TCP1, subunit 3 isoform c [Homo
           sapiens]
          Length = 507

 Score =  991 bits (2563), Expect = 0.0
 Identities = 507/507 (100%), Positives = 507/507 (100%)

Query: 1   MMGHRPVLVLSQNTKRESGRKVQSGNINAAKIQVQHPAAKSMIEISRTQDEEVGDGTTSV 60
           MMGHRPVLVLSQNTKRESGRKVQSGNINAAKIQVQHPAAKSMIEISRTQDEEVGDGTTSV
Sbjct: 1   MMGHRPVLVLSQNTKRESGRKVQSGNINAAKIQVQHPAAKSMIEISRTQDEEVGDGTTSV 60

Query: 61  IILAGEMLSVAEHFLEQQMHPTVVISAYRKALDDMISTLKKISIPVDISDSDMMLNIINS 120
           IILAGEMLSVAEHFLEQQMHPTVVISAYRKALDDMISTLKKISIPVDISDSDMMLNIINS
Sbjct: 61  IILAGEMLSVAEHFLEQQMHPTVVISAYRKALDDMISTLKKISIPVDISDSDMMLNIINS 120

Query: 121 SITTKAISRWSSLACNIALDAVKMVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGV 180
           SITTKAISRWSSLACNIALDAVKMVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGV
Sbjct: 121 SITTKAISRWSSLACNIALDAVKMVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGV 180

Query: 181 MINKDVTHPRMRRYIKNPRIVLLDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQL 240
           MINKDVTHPRMRRYIKNPRIVLLDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQL
Sbjct: 181 MINKDVTHPRMRRYIKNPRIVLLDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQL 240

Query: 241 CEDIIQLKPDVVITEKGISDLAQHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEEL 300
           CEDIIQLKPDVVITEKGISDLAQHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEEL
Sbjct: 241 CEDIIQLKPDVVITEKGISDLAQHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEEL 300

Query: 301 REDDVGTGAGLLEIKKIGDEYFTFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVC 360
           REDDVGTGAGLLEIKKIGDEYFTFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVC
Sbjct: 301 REDDVGTGAGLLEIKKIGDEYFTFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVC 360

Query: 361 RNVLLDPQLVPGGGASEMAVAHALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGAS 420
           RNVLLDPQLVPGGGASEMAVAHALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGAS
Sbjct: 361 RNVLLDPQLVPGGGASEMAVAHALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGAS 420

Query: 421 TIRLLTSLRAKHTQENCETWGVNGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLR 480
           TIRLLTSLRAKHTQENCETWGVNGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLR
Sbjct: 421 TIRLLTSLRAKHTQENCETWGVNGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLR 480

Query: 481 IDDIVSGHKKKGDDQSRQGGAPDAGQE 507
           IDDIVSGHKKKGDDQSRQGGAPDAGQE
Sbjct: 481 IDDIVSGHKKKGDDQSRQGGAPDAGQE 507


>gi|63162572 chaperonin containing TCP1, subunit 3 isoform a [Homo
           sapiens]
          Length = 545

 Score =  972 bits (2514), Expect = 0.0
 Identities = 507/545 (93%), Positives = 507/545 (93%), Gaps = 38/545 (6%)

Query: 1   MMGHRPVLVLSQNTKRESGRKVQSGNINAAK----------------------------- 31
           MMGHRPVLVLSQNTKRESGRKVQSGNINAAK                             
Sbjct: 1   MMGHRPVLVLSQNTKRESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMT 60

Query: 32  ---------IQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPT 82
                    IQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPT
Sbjct: 61  NDGNAILREIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPT 120

Query: 83  VVISAYRKALDDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAV 142
           VVISAYRKALDDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAV
Sbjct: 121 VVISAYRKALDDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAV 180

Query: 143 KMVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVL 202
           KMVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVL
Sbjct: 181 KMVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVL 240

Query: 203 LDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLA 262
           LDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLA
Sbjct: 241 LDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLA 300

Query: 263 QHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYF 322
           QHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYF
Sbjct: 301 QHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYF 360

Query: 323 TFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAH 382
           TFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAH
Sbjct: 361 TFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAH 420

Query: 383 ALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGV 442
           ALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGV
Sbjct: 421 ALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGV 480

Query: 443 NGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDDQSRQGGAP 502
           NGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDDQSRQGGAP
Sbjct: 481 NGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDDQSRQGGAP 540

Query: 503 DAGQE 507
           DAGQE
Sbjct: 541 DAGQE 545


>gi|58761486 chaperonin containing TCP1, subunit 3 isoform b [Homo
           sapiens]
          Length = 544

 Score =  966 bits (2498), Expect = 0.0
 Identities = 506/545 (92%), Positives = 506/545 (92%), Gaps = 39/545 (7%)

Query: 1   MMGHRPVLVLSQNTKRESGRKVQSGNINAAK----------------------------- 31
           MMGHRPVLVLSQNTKRESGRKVQSGNINAAK                             
Sbjct: 1   MMGHRPVLVLSQNTKRESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMT 60

Query: 32  ---------IQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPT 82
                    IQVQHPAAKSMIEISRTQDEEVGDGTTSVIIL GEMLSVAEHFLEQQMHPT
Sbjct: 61  NDGNAILREIQVQHPAAKSMIEISRTQDEEVGDGTTSVIIL-GEMLSVAEHFLEQQMHPT 119

Query: 83  VVISAYRKALDDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAV 142
           VVISAYRKALDDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAV
Sbjct: 120 VVISAYRKALDDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAV 179

Query: 143 KMVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVL 202
           KMVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVL
Sbjct: 180 KMVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVL 239

Query: 203 LDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLA 262
           LDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLA
Sbjct: 240 LDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLA 299

Query: 263 QHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYF 322
           QHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYF
Sbjct: 300 QHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYF 359

Query: 323 TFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAH 382
           TFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAH
Sbjct: 360 TFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAH 419

Query: 383 ALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGV 442
           ALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGV
Sbjct: 420 ALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGV 479

Query: 443 NGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDDQSRQGGAP 502
           NGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDDQSRQGGAP
Sbjct: 480 NGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDDQSRQGGAP 539

Query: 503 DAGQE 507
           DAGQE
Sbjct: 540 DAGQE 544


>gi|24307939 chaperonin containing TCP1, subunit 5 (epsilon) [Homo
           sapiens]
          Length = 541

 Score =  258 bits (658), Expect = 1e-68
 Identities = 155/468 (33%), Positives = 272/468 (58%), Gaps = 12/468 (2%)

Query: 32  IQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPTVVISAYRKA 91
           + V H  AK M+E+S++QD+E+GDGTT V++LAG +L  AE  L++ +HP  +   Y +A
Sbjct: 81  MDVDHQIAKLMVELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRIADGYEQA 140

Query: 92  LDDMISTLKKIS--IPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAVKMVQFEE 149
               I  L KIS  + VDI D++ ++    +++ +K ++        IA++AV  V   E
Sbjct: 141 ARVAIEHLDKISDSVLVDIKDTEPLIQTAKTTLGSKVVNSCHRQMAEIAVNAVLTVADME 200

Query: 150 NGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSSLEY 209
             R+++D +   +VE   GG +ED+ +++GV+++KD +HP+M + +++ +I +L    E 
Sbjct: 201 --RRDVDFE-LIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEP 257

Query: 210 KKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLAQHYLMRA 269
            K +++  +++T  ED+  + + E+E  +++ + I +   ++ I + G  D A H L++ 
Sbjct: 258 PKPKTKHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLAICQWGFDDEANHLLLQN 317

Query: 270 NITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGD--EYFTFITD 327
           N+ A+R V   +   IA A G RIV R  EL  + +G  AGL++    G   +    I  
Sbjct: 318 NLPAVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGF-AGLVQEISFGTTKDKMLVIEQ 376

Query: 328 CKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHALTEK 387
           CK+ +A TI +RG +K I+ E +R+L DA+ V RN++ D ++V GGGA+E++ A A++++
Sbjct: 377 CKNSRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQE 436

Query: 388 SKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGVNGETG 447
           +     +EQ+  RA A ALEVIP  L +N G + I+ +T +RA+  +E     G++    
Sbjct: 437 ADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQVKEMNPALGIDCLHK 496

Query: 448 TLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDDQ 495
              DMK+  + E L  K Q    A +   ++L+IDDI    +K G+ +
Sbjct: 497 GTNDMKQQHVIETLIGKKQQISLATQMVRMILKIDDI----RKPGESE 540


>gi|38455427 chaperonin containing TCP1, subunit 4 (delta) [Homo
           sapiens]
          Length = 539

 Score =  254 bits (650), Expect = 1e-67
 Identities = 152/462 (32%), Positives = 266/462 (57%), Gaps = 10/462 (2%)

Query: 31  KIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPTVVISAYRK 90
           ++QV HPAA+ ++E+S+ QD E GDGTTSV+I+AG +L      L++ +HPT++  +++K
Sbjct: 80  QMQVLHPAARMLVELSKAQDIEAGDGTTSVVIIAGSLLDSCTKLLQKGIHPTIISESFQK 139

Query: 91  ALDDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAVKMVQFEEN 150
           AL+  I  L  +S PV++SD + +LN   +S+ +K +S++SSL   ++++AV  V  +  
Sbjct: 140 ALEKGIEILTDMSRPVELSDRETLLNSATTSLNSKVVSQYSSLLSPMSVNAVMKV-IDPA 198

Query: 151 GRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSSLEYK 210
               +D++    V+K+ GG I+D  ++ G+++ + V++  + R ++  +I L+   L   
Sbjct: 199 TATSVDLRDIKIVKKL-GGTIDDCELVEGLVLTQKVSNSGITR-VEKAKIGLIQFCLSAP 256

Query: 211 KGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGI-----SDLAQHY 265
           K +    I ++      R+L+ E  YI  L + I +   +V++ +K I     SDLA H+
Sbjct: 257 KTDMDNQIVVSDYAQMDRVLREERAYILNLVKQIKKTGCNVLLIQKSILRDALSDLALHF 316

Query: 266 LMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYFTFI 325
           L +  I  I+ + + D   I +  G + V+  ++   D +G+     E+   G      I
Sbjct: 317 LNKMKIMVIKDIEREDIEFICKTIGTKPVAHIDQFTADMLGSAELAEEVNLNGSGKLLKI 376

Query: 326 TDCKDP-KACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHAL 384
           T C  P K  TI++RG++K ++ E ER++ DA+ V R ++    L+ GGGA E+ +A  L
Sbjct: 377 TGCASPGKTVTIVVRGSNKLVIEEAERSIHDALCVIRCLVKKRALIAGGGAPEIELALRL 436

Query: 385 TEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGVNG 444
           TE S+ ++G+E +  RA A A+EVIP TL +N G + I  +T LR +H Q   +T G+N 
Sbjct: 437 TEYSRTLSGMESYCVRAFADAMEVIPSTLAENAGLNPISTVTELRNRHAQGE-KTAGINV 495

Query: 445 ETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVS 486
             G + ++ E  + +PL V +     A ET   +L+IDD+V+
Sbjct: 496 RKGGISNILEELVVQPLLVSVSALTLATETVRSILKIDDVVN 537


>gi|5453607 chaperonin containing TCP1, subunit 7 isoform a [Homo
           sapiens]
          Length = 543

 Score =  245 bits (625), Expect = 8e-65
 Identities = 149/483 (30%), Positives = 249/483 (51%), Gaps = 18/483 (3%)

Query: 32  IQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPTVVISAYRKA 91
           + V HPAAK++++I+++QD EVGDGTTSV +LA E L   + ++E+ +HP ++I A+R A
Sbjct: 69  LDVVHPAAKTLVDIAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEEGLHPQIIIRAFRTA 128

Query: 92  LDDMISTLKKISIPVDISDSDMMLNIIN----SSITTKAISRWSSLACNIALDAVKMVQF 147
               ++ +K+I++ V  +D      ++     +++++K IS+  +    + +DAV M+  
Sbjct: 129 TQLAVNKIKEIAVTVKKADKVEQRKLLEKCAMTALSSKLISQQKAFFAKMVVDAVMMLD- 187

Query: 148 EENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIK---NPRIVLLD 204
                 ++   K   ++K+ GG +EDS ++ GV   K  ++       K   NP+I LL+
Sbjct: 188 ------DLLQLKMIGIKKVQGGALEDSQLVAGVAFKKTFSYAGFEMQPKKYHNPKIALLN 241

Query: 205 SSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLAQH 264
             LE K  +   +I +   ED+  I+  E   +    E I      VV+++  I D+A  
Sbjct: 242 VELELKAEKDNAEIRVHTVEDYQAIVDAEWNILYDKLEKIHHSGAKVVLSKLPIGDVATQ 301

Query: 265 YLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYFTF 324
           Y    ++    RV + D  R   ACG  I +    L  D +G    + E  +IG E + F
Sbjct: 302 YFADRDMFCAGRVPEEDLKRTMMACGGSIQTSVNALSADVLGR-CQVFEETQIGGERYNF 360

Query: 325 ITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHAL 384
            T C   K CT +LRG +++ + E ER+L DA+ + R  + +  +V GGGA EM ++  L
Sbjct: 361 FTGCPKAKTCTFILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYL 420

Query: 385 TEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETW-GVN 443
            + S+ + G +Q    A A+ALE+IPR L  N G     +L  LRA+H Q    TW GV+
Sbjct: 421 RDYSRTIPGKQQLLIGAYAKALEIIPRQLCDNAGFDATNILNKLRARHAQGG--TWYGVD 478

Query: 444 GETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDDQSRQGGAPD 503
                + D  E  +WEP  V++     A E A L++ +D+ +   +   D  +  G    
Sbjct: 479 INNEDIADNFEAFVWEPAMVRINALTAASEAACLIVSVDETIKNPRSTVDAPTAAGRGRG 538

Query: 504 AGQ 506
            G+
Sbjct: 539 RGR 541


>gi|57863257 T-complex protein 1 isoform a [Homo sapiens]
          Length = 556

 Score =  239 bits (611), Expect = 3e-63
 Identities = 158/487 (32%), Positives = 259/487 (53%), Gaps = 17/487 (3%)

Query: 32  IQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPTVVISAYRKA 91
           ++V+HPAAK + E++  QD+EVGDGTTSV+I+A E+L  A+  ++Q++HPT VIS YR A
Sbjct: 65  LEVEHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLA 124

Query: 92  LDDMISTL-KKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAVKMVQFEE- 149
             + +  + + + +  D    D ++N   +S+++K I        N+ +DAV  +++ + 
Sbjct: 125 CKEAVRYINENLIVNTDELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIKYTDI 184

Query: 150 NGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSSLEY 209
            G+    +     + K  G    +S ++ G  +N  V    M + I N +I  LD SL+ 
Sbjct: 185 RGQPRYPVNS-VNILKAHGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFSLQK 243

Query: 210 KKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLAQHYLMRA 269
            K +    + IT  E   +I Q E +  ++  + I+    +V++T  GI D+   Y + A
Sbjct: 244 TKMKLGVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMCLKYFVEA 303

Query: 270 NITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEI-----KKIGDEYFTF 324
              A+RRV K D  RIA+A GA I+S    L  ++    A L +      ++I D+    
Sbjct: 304 GAMAVRRVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELIL 363

Query: 325 ITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHAL 384
           I + K   + +I+LRGA+  +  E+ER+L DA+ V + VL    +VPGGGA E A++  L
Sbjct: 364 IKNTKARTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYL 423

Query: 385 TEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQ-------ENC 437
              + +M   EQ      A++L VIP TL  N    +  L+  LRA H +       +N 
Sbjct: 424 ENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNL 483

Query: 438 ETWGVNGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDDQSR 497
           +  G++   G   D K+ G++EP  VK+++ K A E A+ +LRIDD++  H +  DD  +
Sbjct: 484 KWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLHPESKDD--K 541

Query: 498 QGGAPDA 504
            G   DA
Sbjct: 542 HGSYEDA 548


>gi|4502643 chaperonin containing TCP1, subunit 6A isoform a [Homo
           sapiens]
          Length = 531

 Score =  224 bits (570), Expect = 2e-58
 Identities = 128/472 (27%), Positives = 263/472 (55%), Gaps = 16/472 (3%)

Query: 23  QSGNINAAKIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPT 82
           + GN+   ++Q+QHP A  + +++  QD+  GDGTTS +++ GE+L  A+ ++ + +HP 
Sbjct: 58  KDGNVLLHEMQIQHPTASLIAKVATAQDDITGDGTTSNVLIIGELLKQADLYISEGLHPR 117

Query: 83  VVISAYRKALDDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAV 142
           ++   +  A +  +  L+++ +  ++ D + ++++  +S+ TK  +  + +     +D++
Sbjct: 118 IITEGFEAAKEKALQFLEEVKVSREM-DRETLIDVARTSLRTKVHAELADVLTEAVVDSI 176

Query: 143 KMVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVL 202
             ++ ++   + ID+     +E +      D+ ++RG++++    HP M++ +++  I+ 
Sbjct: 177 LAIKKQD---EPIDLFMIEIME-MKHKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILT 232

Query: 203 LDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDV---------VI 253
            + SLEY+K E  +       E+  ++++ E ++I+   + II+LK  V         VI
Sbjct: 233 CNVSLEYEKTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVI 292

Query: 254 TEKGISDLAQHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLE 313
            +KGI   +   L +  I A+RR ++ +  R+  ACG   ++  ++L  D +G  AGL+ 
Sbjct: 293 NQKGIDPFSLDALSKEGIVALRRAKRRNMERLTLACGGVALNSFDDLSPDCLGH-AGLVY 351

Query: 314 IKKIGDEYFTFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGG 373
              +G+E FTFI  C +P++ T+L++G +K  L++++  ++D ++  +N + D  +VPG 
Sbjct: 352 EYTLGEEKFTFIEKCNNPRSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGA 411

Query: 374 GASEMAVAHALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHT 433
           GA E+A+A AL +   ++ G  Q   +A A AL +IP+ L QN G      L  ++A+H+
Sbjct: 412 GAVEVAMAEALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHS 471

Query: 434 QENCETWGVNGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIV 485
            E+ +  GV+  TG  +   E+G+W+   VK Q   +    A  +L +D+I+
Sbjct: 472 -ESGQLVGVDLNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIM 522


>gi|58331173 chaperonin containing TCP1, subunit 6B [Homo sapiens]
          Length = 530

 Score =  219 bits (558), Expect = 5e-57
 Identities = 129/473 (27%), Positives = 258/473 (54%), Gaps = 18/473 (3%)

Query: 23  QSGNINAAKIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPT 82
           + GN+   ++Q+QHP A  + +++  QD+  GDGTTS +++ GE+L  A+ ++ + +HP 
Sbjct: 58  KDGNVLLDEMQIQHPTASLIAKVATAQDDVTGDGTTSNVLIIGELLKQADLYISEGLHPR 117

Query: 83  VVISAYRKALDDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAV 142
           ++   +  A    +  L+++ +  ++    ++L++  +S+ TK  +  + +   + +D+V
Sbjct: 118 IIAEGFEAAKIKALEVLEEVKVTKEMKRK-ILLDVARTSLQTKVHAELADVLTEVVVDSV 176

Query: 143 KMVQFEENGRKEIDIKKY-ARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIV 201
             V+     R    I  +   + ++   +  D+ +++G++++    HP M++ +++  I+
Sbjct: 177 LAVR-----RPGYPIDLFMVEIMEMKHKLGTDTKLIQGLVLDHGARHPDMKKRVEDAFIL 231

Query: 202 LLDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDV---------V 252
           + + SLEY+K E  +       E+  ++++ E ++I+   + II LK  V         V
Sbjct: 232 ICNVSLEYEKTEVNSGFFYKTAEEKEKLVKAERKFIEDRVQKIIDLKDKVCAQSNKGFVV 291

Query: 253 ITEKGISDLAQHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLL 312
           I +KGI   +   L +  I A+RR ++ +  R++ ACG   V+  E+L  D +G  AGL+
Sbjct: 292 INQKGIDPFSLDSLAKHGIVALRRAKRRNMERLSLACGGMAVNSFEDLTVDCLGH-AGLV 350

Query: 313 EIKKIGDEYFTFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPG 372
               +G+E FTFI +C +P + T+L++G +K  L++V+  ++D ++  +N + D  +VPG
Sbjct: 351 YEYTLGEEKFTFIEECVNPCSVTLLVKGPNKHTLTQVKDAIRDGLRAIKNAIEDGCMVPG 410

Query: 373 GGASEMAVAHALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKH 432
            GA E+A+A AL     ++ G  +   +A A AL +IP+ L QN G      L  ++A+H
Sbjct: 411 AGAIEVAMAEALVTYKNSIKGRARLGVQAFADALLIIPKVLAQNAGYDPQETLVKVQAEH 470

Query: 433 TQENCETWGVNGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIV 485
             E+ +  GV+  TG  +   + G+W+   VK Q   +    A  +L +D+I+
Sbjct: 471 V-ESKQLVGVDLNTGEPMVAADAGVWDNYCVKKQLLHSCTVIATNILLVDEIM 522


>gi|5453603 chaperonin containing TCP1, subunit 2 [Homo sapiens]
          Length = 535

 Score =  196 bits (498), Expect = 4e-50
 Identities = 139/466 (29%), Positives = 243/466 (52%), Gaps = 18/466 (3%)

Query: 32  IQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPTVVISAYRKA 91
           I V +PAAK ++++SR QD+EVGDGTTSV +LA E+L  AE  + +++HP  +I+ +R+A
Sbjct: 74  IGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQTIIAGWREA 133

Query: 92  LDDMISTLKKISIPVDISDSDM-----MLNIINSSITTKAISRWSSLACNIALDAVKMVQ 146
                  L  +S  VD    ++     ++NI  +++++K ++        +A++AV  ++
Sbjct: 134 TKAAREAL--LSSAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFTKLAVEAVLRLK 191

Query: 147 FEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSS 206
              N      IKK        GG + DS +  G +++K +   + +R I+N +I++ ++ 
Sbjct: 192 GSGNLEAIHIIKKL-------GGSLADSYLDEGFLLDKKIGVNQPKR-IENAKILIANTG 243

Query: 207 LEYKKGES-QTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLAQHY 265
           ++  K +   + + +        I   E+E +++  E I++   +  I  + I +  +  
Sbjct: 244 MDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYPEQL 303

Query: 266 LMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYFTFI 325
              A + AI         R+A   G  I S  +      +G+   L+E   IG++     
Sbjct: 304 FGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGS-CKLIEEVMIGEDKLIHF 362

Query: 326 TDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHALT 385
           +     +ACTI+LRGA+++IL E ER+L DA+ V    + D + V GGG SEM +AHA+T
Sbjct: 363 SGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCSEMLMAHAVT 422

Query: 386 EKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGVNGE 445
           + +    G E     + A+AL ++P  +  N G  +  L+  LRA H++ N  T G++  
Sbjct: 423 QLANRTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGN-TTAGLDMR 481

Query: 446 TGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKK 491
            GT+ DM  LGI E   VK Q   +A E A ++LR+D+I+    +K
Sbjct: 482 EGTIGDMAILGITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPRK 527


>gi|48762932 chaperonin containing TCP1, subunit 8 (theta) [Homo
           sapiens]
          Length = 548

 Score =  182 bits (463), Expect = 5e-46
 Identities = 139/485 (28%), Positives = 232/485 (47%), Gaps = 31/485 (6%)

Query: 31  KIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPTVVISAYRK 90
           +++VQHPAAK ++  S  Q++EVGDGT  V++ AG +L +AE  L   +  + VI  Y  
Sbjct: 75  ELEVQHPAAKMIVMASHMQEQEVGDGTNFVLVFAGALLELAEELLRIGLSVSEVIEGYEI 134

Query: 91  ALDDMISTLKKISI--PVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAVKMVQFE 148
           A       L  +      ++ D D + +++ +SI +K       LA  IA   V +  F 
Sbjct: 135 ACRKAHEILPNLVCCSAKNLRDIDEVSSLLRTSIMSKQYGNEVFLAKLIAQACVSI--FP 192

Query: 149 ENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINK----DVTHPRMRRYIKNPRIVLLD 204
           ++G   +D     RV KI G  I  S VL G++  K    DVT       +K+ +I +  
Sbjct: 193 DSGHFNVD---NIRVCKILGSGISSSSVLHGMVFKKETEGDVTS------VKDAKIAVYS 243

Query: 205 SSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLAQH 264
              +    E++  + I   E+     + EE  +    + I     +VV+T   ++D+A H
Sbjct: 244 CPFDGMITETKGTVLIKTAEELMNFSKGEENLMDAQVKAIADTGANVVVTGGKVADMALH 303

Query: 265 YLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGD-EYFT 323
           Y  + NI  +R   K D  R+ +  GA  + R      +++G     + + ++GD +   
Sbjct: 304 YANKYNIMLVRLNSKWDLRRLCKTVGATALPRLTPPVLEEMGH-CDSVYLSEVGDTQVVV 362

Query: 324 FITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHA 383
           F  + +D    TI+LRG++  ++ ++ER + D +   + +  D +LVPGGGA+E+ +A  
Sbjct: 363 FKHEKEDGAISTIVLRGSTDNLMDDIERAVDDGVNTFKVLTRDKRLVPGGGATEIELAKQ 422

Query: 384 LTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCET-WGV 442
           +T   +   G+EQ+  +  A+A E IPR L +N G     +++ L A H + N      +
Sbjct: 423 ITSYGETCPGLEQYAIKKFAEAFEAIPRALAENSGVKANEVISKLYAVHQEGNKNVGLDI 482

Query: 443 NGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIV-----------SGHKKK 491
             E   + DM E GI +    K    K A   AV +LR+D I+           SG K  
Sbjct: 483 EAEVPAVKDMLEAGILDTYLGKYWAIKLATNAAVTVLRVDQIIMAKPAGGPKPPSGKKDW 542

Query: 492 GDDQS 496
            DDQ+
Sbjct: 543 DDDQN 547


>gi|58331171 chaperonin containing TCP1, subunit 6A isoform b [Homo
           sapiens]
          Length = 486

 Score =  181 bits (460), Expect = 1e-45
 Identities = 121/470 (25%), Positives = 250/470 (53%), Gaps = 24/470 (5%)

Query: 30  AKIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGE---MLSVAEHFL--EQQMHPTVV 84
           A + V   AA+ + ++ RT    +G   T  ++++G     L+   + L  E  +HP ++
Sbjct: 18  AALAVNISAARGLQDVLRTN---LGPKGTMKMLVSGAGDIKLTKDGNVLLHEMGLHPRII 74

Query: 85  ISAYRKALDDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAVKM 144
              +  A +  +  L+++ +  ++ D + ++++  +S+ TK  +  + +     +D++  
Sbjct: 75  TEGFEAAKEKALQFLEEVKVSREM-DRETLIDVARTSLRTKVHAELADVLTEAVVDSILA 133

Query: 145 VQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLD 204
           ++ ++   + ID+     +E +      D+ ++RG++++    HP M++ +++  I+  +
Sbjct: 134 IKKQD---EPIDLFMIEIME-MKHKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCN 189

Query: 205 SSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDV---------VITE 255
            SLEY+K E  +       E+  ++++ E ++I+   + II+LK  V         VI +
Sbjct: 190 VSLEYEKTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQ 249

Query: 256 KGISDLAQHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIK 315
           KGI   +   L +  I A+RR ++ +  R+  ACG   ++  ++L  D +G  AGL+   
Sbjct: 250 KGIDPFSLDALSKEGIVALRRAKRRNMERLTLACGGVALNSFDDLSPDCLGH-AGLVYEY 308

Query: 316 KIGDEYFTFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGA 375
            +G+E FTFI  C +P++ T+L++G +K  L++++  ++D ++  +N + D  +VPG GA
Sbjct: 309 TLGEEKFTFIEKCNNPRSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGA 368

Query: 376 SEMAVAHALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQE 435
            E+A+A AL +   ++ G  Q   +A A AL +IP+ L QN G      L  ++A+H+ E
Sbjct: 369 VEVAMAEALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHS-E 427

Query: 436 NCETWGVNGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIV 485
           + +  GV+  TG  +   E+G+W+   VK Q   +    A  +L +D+I+
Sbjct: 428 SGQLVGVDLNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIM 477


>gi|57863259 T-complex protein 1 isoform b [Homo sapiens]
          Length = 401

 Score =  167 bits (424), Expect = 2e-41
 Identities = 121/396 (30%), Positives = 198/396 (50%), Gaps = 16/396 (4%)

Query: 122 ITTKAISRWSSLACNIALDAVKMVQFEE-NGRKEIDIKKYARVEKIPGGIIEDSCVLRGV 180
           +++K I        N+ +DAV  +++ +  G+    +     + K  G    +S ++ G 
Sbjct: 1   MSSKIIGINGDFFANMVVDAVLAIKYTDIRGQPRYPVNS-VNILKAHGRSQMESMLISGY 59

Query: 181 MINKDVTHPRMRRYIKNPRIVLLDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQL 240
            +N  V    M + I N +I  LD SL+  K +    + IT  E   +I Q E +  ++ 
Sbjct: 60  ALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPEKLDQIRQRESDITKER 119

Query: 241 CEDIIQLKPDVVITEKGISDLAQHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEEL 300
            + I+    +V++T  GI D+   Y + A   A+RRV K D  RIA+A GA I+S    L
Sbjct: 120 IQKILATGANVILTTGGIDDMCLKYFVEAGAMAVRRVLKRDLKRIAKASGATILSTLANL 179

Query: 301 REDDVGTGAGLLEIK-----KIGDEYFTFITDCKDPKACTILLRGASKEILSEVERNLQD 355
             ++    A L + +     +I D+    I + K   + +I+LRGA+  +  E+ER+L D
Sbjct: 180 EGEETFEAAMLGQAEEVVQERICDDELILIKNTKARTSASIILRGANDFMCDEMERSLHD 239

Query: 356 AMQVCRNVLLDPQLVPGGGASEMAVAHALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQ 415
           A+ V + VL    +VPGGGA E A++  L   + +M   EQ      A++L VIP TL  
Sbjct: 240 ALCVVKRVLESKSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLAV 299

Query: 416 NCGASTIRLLTSLRAKHTQ-------ENCETWGVNGETGTLVDMKELGIWEPLAVKLQTY 468
           N    +  L+  LRA H +       +N +  G++   G   D K+ G++EP  VK+++ 
Sbjct: 300 NAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSL 359

Query: 469 KTAVETAVLLLRIDDIVSGHKKKGDDQSRQGGAPDA 504
           K A E A+ +LRIDD++  H +  DD  + G   DA
Sbjct: 360 KFATEAAITILRIDDLIKLHPESKDD--KHGSYEDA 393


>gi|58331185 chaperonin containing TCP1, subunit 7 isoform b [Homo
           sapiens]
          Length = 339

 Score =  163 bits (413), Expect = 3e-40
 Identities = 104/338 (30%), Positives = 162/338 (47%), Gaps = 7/338 (2%)

Query: 173 DSCVLRGVMINKDVTHPRMRRYIK---NPRIVLLDSSLEYKKGESQTDIEITREEDFTRI 229
           DS ++ GV   K  ++       K   NP+I LL+  LE K  +   +I +   ED+  I
Sbjct: 3   DSQLVAGVAFKKTFSYAGFEMQPKKYHNPKIALLNVELELKAEKDNAEIRVHTVEDYQAI 62

Query: 230 LQMEEEYIQQLCEDIIQLKPDVVITEKGISDLAQHYLMRANITAIRRVRKTDNNRIARAC 289
           +  E   +    E I      VV+++  I D+A  Y    ++    RV + D  R   AC
Sbjct: 63  VDAEWNILYDKLEKIHHSGAKVVLSKLPIGDVATQYFADRDMFCAGRVPEEDLKRTMMAC 122

Query: 290 GARIVSRPEELREDDVGTGAGLLEIKKIGDEYFTFITDCKDPKACTILLRGASKEILSEV 349
           G  I +    L  D +G    + E  +IG E + F T C   K CT +LRG +++ + E 
Sbjct: 123 GGSIQTSVNALSADVLGR-CQVFEETQIGGERYNFFTGCPKAKTCTFILRGGAEQFMEET 181

Query: 350 ERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHALTEKSKAMTGVEQWPYRAVAQALEVI 409
           ER+L DA+ + R  + +  +V GGGA EM ++  L + S+ + G +Q    A A+ALE+I
Sbjct: 182 ERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYLRDYSRTIPGKQQLLIGAYAKALEII 241

Query: 410 PRTLIQNCGASTIRLLTSLRAKHTQENCETW-GVNGETGTLVDMKELGIWEPLAVKLQTY 468
           PR L  N G     +L  LRA+H Q    TW GV+     + D  E  +WEP  V++   
Sbjct: 242 PRQLCDNAGFDATNILNKLRARHAQGG--TWYGVDINNEDIADNFEAFVWEPAMVRINAL 299

Query: 469 KTAVETAVLLLRIDDIVSGHKKKGDDQSRQGGAPDAGQ 506
             A E A L++ +D+ +   +   D  +  G     G+
Sbjct: 300 TAASEAACLIVSVDETIKNPRSTVDAPTAAGRGRGRGR 337


>gi|7657253 T-complex protein 1 [Homo sapiens]
          Length = 557

 Score =  127 bits (319), Expect = 2e-29
 Identities = 110/469 (23%), Positives = 209/469 (44%), Gaps = 34/469 (7%)

Query: 32  IQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPTVVISAYRKA 91
           ++++HPAA  + E  +TQ E  GDGT  V++L   +L  AE  L+  +    +  AY  A
Sbjct: 80  LELEHPAAWLLREAGQTQAENSGDGTAFVVLLTEALLEQAEQLLKAGLPRPQLREAYATA 139

Query: 92  LDDMISTLKKISIPV--DISDSDMMLNIINSSITTKAISRWSSLACNIALDAVKMVQFEE 149
             ++++TL  ++I     + D    L+ + ++ T   +   + L  + A  A+K +    
Sbjct: 140 TAEVLATLPSLAIQSLGPLEDPSWALHSVMNTHTLSPMDHLTKLVAH-ACWAIKELDGSF 198

Query: 150 NGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSSLEY 209
              +         V  +PGG +EDSC+L G+ I+  +   +M   +   R+ L       
Sbjct: 199 KPER-------VGVCALPGGTLEDSCLLPGLAISGKLCG-QMATVLSGARVALFACPFGP 250

Query: 210 KKGESQTDIEITREEDFTRIL----QMEEEYIQQLCEDIIQLKPDVVITEKGISDLAQHY 265
               +     ++   D  +      Q+ E+ + QL    I +   +   ++    LA  Y
Sbjct: 251 AHPNAPATARLSSPADLAQFSKGSDQLLEKQVGQLAAAGINVAVVLGEVDEETLTLADKY 310

Query: 266 LM-----RANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDE 320
            +     R+ +  I      D   + R    +   + + +   ++G G  ++        
Sbjct: 311 GIVVIQARSWMEIIYLSEVLDTPLLPRLLPPQRPGKCQRVYRQELGDGLAVV-------- 362

Query: 321 YFTFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAV 380
              F  +C    A T++LRGA+ + L   E+ +   +     +  DP+L+PG GA+EMA+
Sbjct: 363 ---FEWECTGTPALTVVLRGATTQGLRSAEQAVYHGIDAYFQLCQDPRLIPGAGATEMAL 419

Query: 381 AHALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETW 440
           A  L++K   + G     + A A AL+ +P+TL +N G +   ++  +   H   N    
Sbjct: 420 AKMLSDKGSRLEGPSGPAFLAFAWALKYLPKTLAENAGLAVSDVMAEMSGVHQGGNL-LM 478

Query: 441 GVNGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHK 489
           GV   T  ++++ + G+W+ L VK Q ++   E  + L+ +D+IV   K
Sbjct: 479 GVG--TEGIINVAQEGVWDTLIVKAQGFRAVAEVVLQLVTVDEIVVAKK 525


>gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III
           isoform 2 [Homo sapiens]
          Length = 2098

 Score = 98.6 bits (244), Expect = 1e-20
 Identities = 68/232 (29%), Positives = 119/232 (51%), Gaps = 12/232 (5%)

Query: 128 SRWSSLACNIALDAVKMVQFE-ENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDV 186
           S W  +  ++    V+ V+ + +N   ++DI+++  ++KIPGG   DS V+ G +  K++
Sbjct: 631 SSWRDIIVSLVCQVVQTVRPDVKNQDDDMDIRQFVHIKKIPGGKKFDSVVVNGFVCTKNI 690

Query: 187 THPRMRRYIKNPRIVLLDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQ 246
            H +M   IKNP+I+LL  S+EY   E       T+      I+  E E+++   + I+ 
Sbjct: 691 AHKKMSSCIKNPKILLLKCSIEYLYREE------TKFTCIDPIVLQEREFLKNYVQRIVD 744

Query: 247 LKPDVVITEKGISDLAQHYLMRANITAIRRVRKTDNNRIARAC-GARIVSRPEELREDDV 305
           ++P +V+ EK +S +AQ  L+   IT +  V+     RI+R   G  ++S  + L +  +
Sbjct: 745 VRPTLVLVEKTVSRIAQDMLLEHGITLVINVKSQVLERISRMTQGDLVMSMDQLLTKPHL 804

Query: 306 GT-GAGLLEIKKIGDEY---FTFITDCKDPKACTILLRGASKEILSEVERNL 353
           GT     ++I ++ +E      F   C     CTI LRG S   L+ V+  L
Sbjct: 805 GTCHKFYMQIFQLPNEQTKTLMFFEGCPQHLGCTIKLRGGSDYELARVKEIL 856


>gi|9055272 McKusick-Kaufman syndrome protein [Homo sapiens]
          Length = 570

 Score = 56.2 bits (134), Expect = 7e-08
 Identities = 77/365 (21%), Positives = 145/365 (39%), Gaps = 18/365 (4%)

Query: 34  VQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPTVVISAYRKALD 93
           V HP  K +    +       D      IL   ++   E+     + PT VI   +  L 
Sbjct: 69  VTHPILKILTASIQNHVSSFSDCGLFTAILCCNLI---ENVQRLGLTPTTVIRLNKHLLS 125

Query: 94  DMISTLKKIS----IPVDISDSDMMLNIINSSITTKA---ISRWSSLACNIALDAVKMVQ 146
             IS LK  +    IPVD S + ++L ++ S +T+K    ++R  +   +  +    ++ 
Sbjct: 126 LCISYLKSETCGCRIPVDFSSTQILLCLVRSILTSKPACMLTRKETEHVSALILRAFLLT 185

Query: 147 FEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSS 206
             EN    I + K + +  + G  + DS VL G++I            IK    + +   
Sbjct: 186 IPENAEGHIILGK-SLIVPLKGQRVIDSTVLPGILIEMSEVQLMRLLPIKKSTALKVALF 244

Query: 207 LEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCE---DIIQLKPDVVITEKGISDLAQ 263
                G++    E T    +   + +E   + QL      +I    D+V+ +K I    +
Sbjct: 245 CTTLSGDTSDTGEGTVVVSYG--VSLENAVLDQLLNLGRQLISDHVDLVLCQKVIHPSLK 302

Query: 264 HYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYFT 323
            +L    I AI R+  T    + +  G + +     +  +  G+   +   K     +F 
Sbjct: 303 QFLNMHRIIAIDRIGVTLMEPLTKMTGTQPIGSLGSICPNSYGSVKDVCTAKFGSKHFFH 362

Query: 324 FITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHA 383
            I +  +   C++LL   +     E++   Q A+ V +  L +P  + GGG +E  +A  
Sbjct: 363 LIPN--EATICSLLLCNRNDTAWDELKLTCQTALHVLQLTLKEPWALLGGGCTETHLAAY 420

Query: 384 LTEKS 388
           +  K+
Sbjct: 421 IRHKT 425


>gi|25914754 McKusick-Kaufman syndrome protein [Homo sapiens]
          Length = 570

 Score = 56.2 bits (134), Expect = 7e-08
 Identities = 77/365 (21%), Positives = 145/365 (39%), Gaps = 18/365 (4%)

Query: 34  VQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPTVVISAYRKALD 93
           V HP  K +    +       D      IL   ++   E+     + PT VI   +  L 
Sbjct: 69  VTHPILKILTASIQNHVSSFSDCGLFTAILCCNLI---ENVQRLGLTPTTVIRLNKHLLS 125

Query: 94  DMISTLKKIS----IPVDISDSDMMLNIINSSITTKA---ISRWSSLACNIALDAVKMVQ 146
             IS LK  +    IPVD S + ++L ++ S +T+K    ++R  +   +  +    ++ 
Sbjct: 126 LCISYLKSETCGCRIPVDFSSTQILLCLVRSILTSKPACMLTRKETEHVSALILRAFLLT 185

Query: 147 FEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSS 206
             EN    I + K + +  + G  + DS VL G++I            IK    + +   
Sbjct: 186 IPENAEGHIILGK-SLIVPLKGQRVIDSTVLPGILIEMSEVQLMRLLPIKKSTALKVALF 244

Query: 207 LEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCE---DIIQLKPDVVITEKGISDLAQ 263
                G++    E T    +   + +E   + QL      +I    D+V+ +K I    +
Sbjct: 245 CTTLSGDTSDTGEGTVVVSYG--VSLENAVLDQLLNLGRQLISDHVDLVLCQKVIHPSLK 302

Query: 264 HYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYFT 323
            +L    I AI R+  T    + +  G + +     +  +  G+   +   K     +F 
Sbjct: 303 QFLNMHRIIAIDRIGVTLMEPLTKMTGTQPIGSLGSICPNSYGSVKDVCTAKFGSKHFFH 362

Query: 324 FITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHA 383
            I +  +   C++LL   +     E++   Q A+ V +  L +P  + GGG +E  +A  
Sbjct: 363 LIPN--EATICSLLLCNRNDTAWDELKLTCQTALHVLQLTLKEPWALLGGGCTETHLAAY 420

Query: 384 LTEKS 388
           +  K+
Sbjct: 421 IRHKT 425


>gi|41399285 chaperonin [Homo sapiens]
          Length = 573

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 106/500 (21%), Positives = 196/500 (39%), Gaps = 67/500 (13%)

Query: 31  KIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPTVVISAYRK 90
           K + ++  AK + +++   +EE GDGTT+  +LA  +       + +  +P  +      
Sbjct: 87  KDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVML 146

Query: 91  ALDDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAVKMVQFEEN 150
           A+D +I+ LKK S PV   +    +  I+++   K I        NI  DA+K V     
Sbjct: 147 AVDAVIAELKKQSKPVTTPEEIAQVATISAN-GDKEIG-------NIISDAMKKV----- 193

Query: 151 GRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDS----- 205
           GRK +   K  +       IIE     RG +    +   + ++       VLL       
Sbjct: 194 GRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISS 253

Query: 206 ------SLEYKKGESQTDIEITREED----FTRILQMEEEYIQQLC-------------- 241
                 +LE      +  + I  + D     T +L   +  +Q +               
Sbjct: 254 IQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQL 313

Query: 242 EDIIQLKPDVVITEKGIS----DLAQHYLMRANITAIRRVRKTDNNRIARACG--ARIVS 295
           +D+       V  E+G++    D+  H L +     + +    D+  + +  G  A+I  
Sbjct: 314 KDMAIATGGAVFGEEGLTLNLEDVQPHDLGKVGEVIVTK----DDAMLLKGKGDKAQIEK 369

Query: 296 RPEELRED-DVGTGAGLLEIKKIGDEYFTFITDCKDPKACTILLRGASKEILSEVERNLQ 354
           R +E+ E  DV T     E +K+ +E    ++D        + + G S   ++E +  + 
Sbjct: 370 RIQEIIEQLDVTTSE--YEKEKL-NERLAKLSD----GVAVLKVGGTSDVEVNEKKDRVT 422

Query: 355 DAMQVCRNVLLDPQLVPGGGASEMAVAHALTEKSKAMTGVEQWPYRAVAQALEVIPRTLI 414
           DA+   R   ++  +V GGG + +    AL   + A    ++     + + L++   T+ 
Sbjct: 423 DALNATR-AAVEEGIVLGGGCALLRCIPALDSLTPANED-QKIGIEIIKRTLKIPAMTIA 480

Query: 415 QNCGASTIRLLTSLRAKHTQENCETWGVNGETGTLVDMKELGIWEPLAVKLQTYKTAVET 474
           +N G        SL  +   ++    G +   G  V+M E GI +P  V       A   
Sbjct: 481 KNAGVE-----GSLIVEKIMQSSSEVGYDAMAGDFVNMVEKGIIDPTKVVRTALLDAAGV 535

Query: 475 AVLLLRIDDIVSGHKKKGDD 494
           A LL   + +V+   K+  D
Sbjct: 536 ASLLTTAEVVVTEIPKEEKD 555


>gi|31542947 chaperonin [Homo sapiens]
          Length = 573

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 106/500 (21%), Positives = 196/500 (39%), Gaps = 67/500 (13%)

Query: 31  KIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPTVVISAYRK 90
           K + ++  AK + +++   +EE GDGTT+  +LA  +       + +  +P  +      
Sbjct: 87  KDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVML 146

Query: 91  ALDDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAVKMVQFEEN 150
           A+D +I+ LKK S PV   +    +  I+++   K I        NI  DA+K V     
Sbjct: 147 AVDAVIAELKKQSKPVTTPEEIAQVATISAN-GDKEIG-------NIISDAMKKV----- 193

Query: 151 GRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDS----- 205
           GRK +   K  +       IIE     RG +    +   + ++       VLL       
Sbjct: 194 GRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISS 253

Query: 206 ------SLEYKKGESQTDIEITREED----FTRILQMEEEYIQQLC-------------- 241
                 +LE      +  + I  + D     T +L   +  +Q +               
Sbjct: 254 IQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQL 313

Query: 242 EDIIQLKPDVVITEKGIS----DLAQHYLMRANITAIRRVRKTDNNRIARACG--ARIVS 295
           +D+       V  E+G++    D+  H L +     + +    D+  + +  G  A+I  
Sbjct: 314 KDMAIATGGAVFGEEGLTLNLEDVQPHDLGKVGEVIVTK----DDAMLLKGKGDKAQIEK 369

Query: 296 RPEELRED-DVGTGAGLLEIKKIGDEYFTFITDCKDPKACTILLRGASKEILSEVERNLQ 354
           R +E+ E  DV T     E +K+ +E    ++D        + + G S   ++E +  + 
Sbjct: 370 RIQEIIEQLDVTTSE--YEKEKL-NERLAKLSD----GVAVLKVGGTSDVEVNEKKDRVT 422

Query: 355 DAMQVCRNVLLDPQLVPGGGASEMAVAHALTEKSKAMTGVEQWPYRAVAQALEVIPRTLI 414
           DA+   R   ++  +V GGG + +    AL   + A    ++     + + L++   T+ 
Sbjct: 423 DALNATR-AAVEEGIVLGGGCALLRCIPALDSLTPANED-QKIGIEIIKRTLKIPAMTIA 480

Query: 415 QNCGASTIRLLTSLRAKHTQENCETWGVNGETGTLVDMKELGIWEPLAVKLQTYKTAVET 474
           +N G        SL  +   ++    G +   G  V+M E GI +P  V       A   
Sbjct: 481 KNAGVE-----GSLIVEKIMQSSSEVGYDAMAGDFVNMVEKGIIDPTKVVRTALLDAAGV 535

Query: 475 AVLLLRIDDIVSGHKKKGDD 494
           A LL   + +V+   K+  D
Sbjct: 536 ASLLTTAEVVVTEIPKEEKD 555


>gi|40217788 Bardet-Biedl syndrome 12 [Homo sapiens]
          Length = 710

 Score = 34.7 bits (78), Expect = 0.21
 Identities = 36/149 (24%), Positives = 65/149 (43%), Gaps = 6/149 (4%)

Query: 166 IPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNP--RIVLLDSSL--EYKKGESQTDIEIT 221
           +PG     SCV  G +    V++  + + ++N   RIVL++  L   Y+         I 
Sbjct: 320 LPGLPETSSCVCPGYITVVSVSNNPVIKELQNQPVRIVLIEGDLTENYRHLGFNKSANIK 379

Query: 222 REEDFTRILQ--MEEEYIQQLCEDIIQLKPDVVITEKGISDLAQHYLMRANITAIRRVRK 279
              D  R+ +   EE +   + + +IQ K ++V+ +  +S+      + +    I  V  
Sbjct: 380 TVLDSMRLQEDSSEELWANHVLQVLIQFKVNLVLVQGNVSERLIEKCINSKRLVIGSVNG 439

Query: 280 TDNNRIARACGARIVSRPEELREDDVGTG 308
           +     A A GA  V+   ++ ED VG G
Sbjct: 440 SVMQAFAEAAGAVQVAYITQVNEDCVGDG 468


>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
           [Homo sapiens]
          Length = 916

 Score = 32.0 bits (71), Expect = 1.4
 Identities = 15/49 (30%), Positives = 27/49 (55%), Gaps = 8/49 (16%)

Query: 4   HRPVLVLSQNTKRESGRKVQSGNINAAKIQVQHPAAKSMIEISRTQDEE 52
           HRP + +S         K+Q   + A K++VQH   + +IE ++ +DE+
Sbjct: 426 HRPPITISS--------KIQKPKVEAPKLKVQHKFVEEIIEETKVEDEK 466


>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
          [Homo sapiens]
          Length = 540

 Score = 32.0 bits (71), Expect = 1.4
 Identities = 15/49 (30%), Positives = 27/49 (55%), Gaps = 8/49 (16%)

Query: 4  HRPVLVLSQNTKRESGRKVQSGNINAAKIQVQHPAAKSMIEISRTQDEE 52
          HRP + +S         K+Q   + A K++VQH   + +IE ++ +DE+
Sbjct: 50 HRPPITISS--------KIQKPKVEAPKLKVQHKFVEEIIEETKVEDEK 90


>gi|14251207 MOV10-like 1 [Homo sapiens]
          Length = 1211

 Score = 31.6 bits (70), Expect = 1.8
 Identities = 22/80 (27%), Positives = 34/80 (42%), Gaps = 1/80 (1%)

Query: 93  DDMISTLKKISIPVDISDSDMMLNIINSSITTKAIS-RWSSLACNIALDAVKMVQFEENG 151
           D M   +  +S+P   + SD  +N +NS    K      SSL  N  +         ENG
Sbjct: 326 DQMCPVVSFVSVPEKENSSDENINSLNSHTKNKTSQMSESSLVNNRGISPGDCTCKGENG 385

Query: 152 RKEIDIKKYARVEKIPGGII 171
            K+  + +    E  PGG++
Sbjct: 386 EKDNILSRKQMTEPEPGGLV 405


>gi|23503243 Ras association (RalGDS/AF-6) domain family
           (N-terminal) member 8 [Homo sapiens]
          Length = 392

 Score = 31.6 bits (70), Expect = 1.8
 Identities = 19/72 (26%), Positives = 38/72 (52%), Gaps = 1/72 (1%)

Query: 215 QTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISD-LAQHYLMRANITA 273
           + D+EI  EE +   LQ+E+E  +QL + + +++  +   E  + D LAQ   M + + A
Sbjct: 215 RNDVEIEEEEFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEA 274

Query: 274 IRRVRKTDNNRI 285
            +  R+    ++
Sbjct: 275 EKLQREVQEAQV 286


>gi|10190716 spindle pole body component 25 [Homo sapiens]
          Length = 224

 Score = 31.6 bits (70), Expect = 1.8
 Identities = 29/130 (22%), Positives = 59/130 (45%), Gaps = 16/130 (12%)

Query: 206 SLEYKKGESQTDIEITREEDFTR---ILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLA 262
           S++ K+ E   ++ +  +   +R   ++Q +++ + +L  ++   K ++ +    I DL 
Sbjct: 48  SVKLKEEERMVEMFLEYQNQISRQNKLIQEKKDNLLKLIAEVKGKKQELEVLTANIQDLK 107

Query: 263 QHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYF 322
           + Y  +     I    K +  R+ R      + +  +L +D +G     LEI+KI  E  
Sbjct: 108 EEYSRKKE--TISTANKANAERLKR------LQKSADLYKDRLG-----LEIRKIYGEKL 154

Query: 323 TFITDCKDPK 332
            FI    DPK
Sbjct: 155 QFIFTNIDPK 164


>gi|11968182 ribosomal protein S18 [Homo sapiens]
          Length = 152

 Score = 31.2 bits (69), Expect = 2.3
 Identities = 23/84 (27%), Positives = 38/84 (45%), Gaps = 3/84 (3%)

Query: 271 ITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIK---KIGDEYFTFITD 327
           ITAI+ V +   + + R     +  R  EL ED+V     +++     KI D +     D
Sbjct: 30  ITAIKGVGRRYAHVVLRKADIDLTKRAGELTEDEVERVITIMQNPRQYKIPDWFLNRQKD 89

Query: 328 CKDPKACTILLRGASKEILSEVER 351
            KD K   +L  G   ++  ++ER
Sbjct: 90  VKDGKYSQVLANGLDNKLREDLER 113


>gi|224593271 intermediate filament tail domain containing 1 isoform
           3 [Homo sapiens]
          Length = 325

 Score = 30.8 bits (68), Expect = 3.0
 Identities = 24/129 (18%), Positives = 53/129 (41%), Gaps = 1/129 (0%)

Query: 22  VQSGNINAAKIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHP 81
           V++G+I  +++Q  H A+   +   + +   +GDG    + L G+   +  H    Q   
Sbjct: 5   VRAGDIGVSRVQTHHNASPFSVPKKQDESPMIGDGEDYFLSLFGDSKKLTAHSNYTQKTL 64

Query: 82  TVVISAYRKALDDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDA 141
                   +      S+L  + I  +++   + + +INSS+  +       L  N+    
Sbjct: 65  KYFSMILEEVGQFTSSSLGDVEI-AEVNVKGLFVKLINSSLDKEMAIGDHILQQNVNGQT 123

Query: 142 VKMVQFEEN 150
           + + +F  N
Sbjct: 124 ISLYRFLPN 132


>gi|26667191 calcium/calmodulin-dependent protein kinase II gamma
           isoform 4 [Homo sapiens]
          Length = 495

 Score = 30.4 bits (67), Expect = 4.0
 Identities = 18/90 (20%), Positives = 45/90 (50%), Gaps = 4/90 (4%)

Query: 157 IKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSSLEYKKGESQT 216
           ++K+    K+ G I+    V R     K + + +    +K P+  ++ ++ +  KG +++
Sbjct: 291 LRKFNARRKLKGAILTTMLVSRNFSAAKSLLNKKSDGGVKEPQTTVVHNATDGIKGSTES 350

Query: 217 DIEITREEDFTRILQMEEEYIQQLCEDIIQ 246
               T +ED    L++ ++ I ++ E +I+
Sbjct: 351 CNTTTEDED----LKVRKQEIIKITEQLIE 376


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.372 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,374,913
Number of Sequences: 37866
Number of extensions: 696158
Number of successful extensions: 2024
Number of sequences better than 10.0: 29
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 1956
Number of HSP's gapped (non-prelim): 34
length of query: 507
length of database: 18,247,518
effective HSP length: 107
effective length of query: 400
effective length of database: 14,195,856
effective search space: 5678342400
effective search space used: 5678342400
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.