Guide to the Human Genome
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Search of human proteins with 58331222

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|58331222 ATPase, class VI, type 11C isoform b [Homo sapiens]
         (1119 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|58331222 ATPase, class VI, type 11C isoform b [Homo sapiens]      2248   0.0  
gi|40316839 ATPase, class VI, type 11C isoform a [Homo sapiens]      2206   0.0  
gi|150421681 ATPase, class VI, type 11A isoform b [Homo sapiens]     1463   0.0  
gi|150421684 ATPase, class VI, type 11A isoform a [Homo sapiens]     1463   0.0  
gi|62632750 ATPase, class VI, type 11B [Homo sapiens]                1207   0.0  
gi|157649069 ATPase, aminophospholipid transporter (APLT), class...   662   0.0  
gi|17978471 ATPase, aminophospholipid transporter (APLT), class ...   656   0.0  
gi|40316837 ATPase, class I, type 8B, member 2 isoform a [Homo s...   634   0.0  
gi|50083277 ATPase class I type 8B member 4 [Homo sapiens]            633   0.0  
gi|117168245 ATPase, aminophospholipid transporter-like, Class I...   622   e-178
gi|5031697 ATPase, class I, type 8B, member 1 [Homo sapiens]          595   e-169
gi|44888835 ATPase, class I, type 8B, member 3 [Homo sapiens]         517   e-146
gi|65301139 ATPase, class II, type 9A [Homo sapiens]                  445   e-124
gi|41327760 ATPase, class II, type 9B [Homo sapiens]                  412   e-115
gi|149944474 ATPase, class V, type 10B [Homo sapiens]                 361   2e-99
gi|222352161 ATPase, class V, type 10D [Homo sapiens]                 348   2e-95
gi|14424433 ATPase, class V, type 10A [Homo sapiens]                  345   1e-94
gi|55743077 ATPase, class I, type 8B, member 2 isoform b [Homo s...   173   7e-43
gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo sa...    85   3e-16
gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo sa...    85   3e-16
gi|66932949 ATPase type 13A4 [Homo sapiens]                            83   1e-15
gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sap...    80   1e-14
gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo sa...    79   2e-14
gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo sa...    79   2e-14
gi|48255951 plasma membrane calcium ATPase 2 isoform 1 [Homo sap...    78   5e-14
gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo sa...    75   5e-13
gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo sa...    75   5e-13
gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens]    67   7e-11
gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapi...    67   9e-11
gi|148839292 ATPase type 13A3 [Homo sapiens]                           64   1e-09

>gi|58331222 ATPase, class VI, type 11C isoform b [Homo sapiens]
          Length = 1119

 Score = 2248 bits (5824), Expect = 0.0
 Identities = 1119/1119 (100%), Positives = 1119/1119 (100%)

Query: 1    MQMVPSLPPASECAGEEKRVGTRTVFVGNHPVSETEAYIAQRFCDNRIVSSKYTLWNFLP 60
            MQMVPSLPPASECAGEEKRVGTRTVFVGNHPVSETEAYIAQRFCDNRIVSSKYTLWNFLP
Sbjct: 1    MQMVPSLPPASECAGEEKRVGTRTVFVGNHPVSETEAYIAQRFCDNRIVSSKYTLWNFLP 60

Query: 61   KNLFEQFRRIANFYFLIIFLVQVTVDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHRAD 120
            KNLFEQFRRIANFYFLIIFLVQVTVDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHRAD
Sbjct: 61   KNLFEQFRRIANFYFLIIFLVQVTVDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHRAD 120

Query: 121  NEVNKSTVYIIENAKRVRKESEKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTAS 180
            NEVNKSTVYIIENAKRVRKESEKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTAS
Sbjct: 121  NEVNKSTVYIIENAKRVRKESEKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTAS 180

Query: 181  LDGESNCKTHYAVRDTIALCTAESIDTLRAAIECEQPQPDLYKFVGRINIYSNSLEAVAR 240
            LDGESNCKTHYAVRDTIALCTAESIDTLRAAIECEQPQPDLYKFVGRINIYSNSLEAVAR
Sbjct: 181  LDGESNCKTHYAVRDTIALCTAESIDTLRAAIECEQPQPDLYKFVGRINIYSNSLEAVAR 240

Query: 241  SLGPENLLLKGATLKNTEKIYGVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLF 300
            SLGPENLLLKGATLKNTEKIYGVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLF
Sbjct: 241  SLGPENLLLKGATLKNTEKIYGVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLF 300

Query: 301  ILLTKAAVCTTLKYVWQSTPYNDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPV 360
            ILLTKAAVCTTLKYVWQSTPYNDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPV
Sbjct: 301  ILLTKAAVCTTLKYVWQSTPYNDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPV 360

Query: 361  SMYVTVEMQKFLGSFFISWDKDFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTEN 420
            SMYVTVEMQKFLGSFFISWDKDFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTEN
Sbjct: 361  SMYVTVEMQKFLGSFFISWDKDFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTEN 420

Query: 421  SMEFIECCIDGHKYKGVTQEVDGLSQTDGTLTYFDKVDKNREELFLRALCLCHTVEIKTN 480
            SMEFIECCIDGHKYKGVTQEVDGLSQTDGTLTYFDKVDKNREELFLRALCLCHTVEIKTN
Sbjct: 421  SMEFIECCIDGHKYKGVTQEVDGLSQTDGTLTYFDKVDKNREELFLRALCLCHTVEIKTN 480

Query: 481  DAVDGATESAELTYISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHT 540
            DAVDGATESAELTYISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHT
Sbjct: 481  DAVDGATESAELTYISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHT 540

Query: 541  LNFDAVRRRMSVIVKTQEGDILLFCKGADSAVFPRVQNHEIELTKVHVERNAMDGYRTLC 600
            LNFDAVRRRMSVIVKTQEGDILLFCKGADSAVFPRVQNHEIELTKVHVERNAMDGYRTLC
Sbjct: 541  LNFDAVRRRMSVIVKTQEGDILLFCKGADSAVFPRVQNHEIELTKVHVERNAMDGYRTLC 600

Query: 601  VAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAA 660
            VAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAA
Sbjct: 601  VAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAA 660

Query: 661  ETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERKEDRLHE 720
            ETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERKEDRLHE
Sbjct: 661  ETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERKEDRLHE 720

Query: 721  LLIEYRKKLLHEFPKSTRSFKKAWTEHQEYGLIIDGSTLSLILNSSQDSSSNNYKSIFLQ 780
            LLIEYRKKLLHEFPKSTRSFKKAWTEHQEYGLIIDGSTLSLILNSSQDSSSNNYKSIFLQ
Sbjct: 721  LLIEYRKKLLHEFPKSTRSFKKAWTEHQEYGLIIDGSTLSLILNSSQDSSSNNYKSIFLQ 780

Query: 781  ICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMILESHVGIGIKGKE 840
            ICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMILESHVGIGIKGKE
Sbjct: 781  ICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMILESHVGIGIKGKE 840

Query: 841  GRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCGF 900
            GRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCGF
Sbjct: 841  GRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCGF 900

Query: 901  SQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPRLYMKISGNAMLQLGPFL 960
            SQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPRLYMKISGNAMLQLGPFL
Sbjct: 901  SQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPRLYMKISGNAMLQLGPFL 960

Query: 961  YWTFLAAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFGTIVFTVLVFTVTLKLALDTRF 1020
            YWTFLAAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFGTIVFTVLVFTVTLKLALDTRF
Sbjct: 961  YWTFLAAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFGTIVFTVLVFTVTLKLALDTRF 1020

Query: 1021 WTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQQRMYFVFAQMLSSVSTWLAIILLIFIS 1080
            WTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQQRMYFVFAQMLSSVSTWLAIILLIFIS
Sbjct: 1021 WTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQQRMYFVFAQMLSSVSTWLAIILLIFIS 1080

Query: 1081 LFPEILLIVLKNVRRRSARNPNLELPMLLSYKHTDSGYS 1119
            LFPEILLIVLKNVRRRSARNPNLELPMLLSYKHTDSGYS
Sbjct: 1081 LFPEILLIVLKNVRRRSARNPNLELPMLLSYKHTDSGYS 1119


>gi|40316839 ATPase, class VI, type 11C isoform a [Homo sapiens]
          Length = 1132

 Score = 2206 bits (5716), Expect = 0.0
 Identities = 1099/1099 (100%), Positives = 1099/1099 (100%)

Query: 1    MQMVPSLPPASECAGEEKRVGTRTVFVGNHPVSETEAYIAQRFCDNRIVSSKYTLWNFLP 60
            MQMVPSLPPASECAGEEKRVGTRTVFVGNHPVSETEAYIAQRFCDNRIVSSKYTLWNFLP
Sbjct: 1    MQMVPSLPPASECAGEEKRVGTRTVFVGNHPVSETEAYIAQRFCDNRIVSSKYTLWNFLP 60

Query: 61   KNLFEQFRRIANFYFLIIFLVQVTVDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHRAD 120
            KNLFEQFRRIANFYFLIIFLVQVTVDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHRAD
Sbjct: 61   KNLFEQFRRIANFYFLIIFLVQVTVDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHRAD 120

Query: 121  NEVNKSTVYIIENAKRVRKESEKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTAS 180
            NEVNKSTVYIIENAKRVRKESEKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTAS
Sbjct: 121  NEVNKSTVYIIENAKRVRKESEKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTAS 180

Query: 181  LDGESNCKTHYAVRDTIALCTAESIDTLRAAIECEQPQPDLYKFVGRINIYSNSLEAVAR 240
            LDGESNCKTHYAVRDTIALCTAESIDTLRAAIECEQPQPDLYKFVGRINIYSNSLEAVAR
Sbjct: 181  LDGESNCKTHYAVRDTIALCTAESIDTLRAAIECEQPQPDLYKFVGRINIYSNSLEAVAR 240

Query: 241  SLGPENLLLKGATLKNTEKIYGVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLF 300
            SLGPENLLLKGATLKNTEKIYGVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLF
Sbjct: 241  SLGPENLLLKGATLKNTEKIYGVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLF 300

Query: 301  ILLTKAAVCTTLKYVWQSTPYNDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPV 360
            ILLTKAAVCTTLKYVWQSTPYNDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPV
Sbjct: 301  ILLTKAAVCTTLKYVWQSTPYNDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPV 360

Query: 361  SMYVTVEMQKFLGSFFISWDKDFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTEN 420
            SMYVTVEMQKFLGSFFISWDKDFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTEN
Sbjct: 361  SMYVTVEMQKFLGSFFISWDKDFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTEN 420

Query: 421  SMEFIECCIDGHKYKGVTQEVDGLSQTDGTLTYFDKVDKNREELFLRALCLCHTVEIKTN 480
            SMEFIECCIDGHKYKGVTQEVDGLSQTDGTLTYFDKVDKNREELFLRALCLCHTVEIKTN
Sbjct: 421  SMEFIECCIDGHKYKGVTQEVDGLSQTDGTLTYFDKVDKNREELFLRALCLCHTVEIKTN 480

Query: 481  DAVDGATESAELTYISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHT 540
            DAVDGATESAELTYISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHT
Sbjct: 481  DAVDGATESAELTYISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHT 540

Query: 541  LNFDAVRRRMSVIVKTQEGDILLFCKGADSAVFPRVQNHEIELTKVHVERNAMDGYRTLC 600
            LNFDAVRRRMSVIVKTQEGDILLFCKGADSAVFPRVQNHEIELTKVHVERNAMDGYRTLC
Sbjct: 541  LNFDAVRRRMSVIVKTQEGDILLFCKGADSAVFPRVQNHEIELTKVHVERNAMDGYRTLC 600

Query: 601  VAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAA 660
            VAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAA
Sbjct: 601  VAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAA 660

Query: 661  ETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERKEDRLHE 720
            ETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERKEDRLHE
Sbjct: 661  ETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERKEDRLHE 720

Query: 721  LLIEYRKKLLHEFPKSTRSFKKAWTEHQEYGLIIDGSTLSLILNSSQDSSSNNYKSIFLQ 780
            LLIEYRKKLLHEFPKSTRSFKKAWTEHQEYGLIIDGSTLSLILNSSQDSSSNNYKSIFLQ
Sbjct: 721  LLIEYRKKLLHEFPKSTRSFKKAWTEHQEYGLIIDGSTLSLILNSSQDSSSNNYKSIFLQ 780

Query: 781  ICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMILESHVGIGIKGKE 840
            ICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMILESHVGIGIKGKE
Sbjct: 781  ICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMILESHVGIGIKGKE 840

Query: 841  GRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCGF 900
            GRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCGF
Sbjct: 841  GRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCGF 900

Query: 901  SQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPRLYMKISGNAMLQLGPFL 960
            SQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPRLYMKISGNAMLQLGPFL
Sbjct: 901  SQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPRLYMKISGNAMLQLGPFL 960

Query: 961  YWTFLAAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFGTIVFTVLVFTVTLKLALDTRF 1020
            YWTFLAAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFGTIVFTVLVFTVTLKLALDTRF
Sbjct: 961  YWTFLAAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFGTIVFTVLVFTVTLKLALDTRF 1020

Query: 1021 WTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQQRMYFVFAQMLSSVSTWLAIILLIFIS 1080
            WTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQQRMYFVFAQMLSSVSTWLAIILLIFIS
Sbjct: 1021 WTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQQRMYFVFAQMLSSVSTWLAIILLIFIS 1080

Query: 1081 LFPEILLIVLKNVRRRSAR 1099
            LFPEILLIVLKNVRRRSAR
Sbjct: 1081 LFPEILLIVLKNVRRRSAR 1099


>gi|150421681 ATPase, class VI, type 11A isoform b [Homo sapiens]
          Length = 1191

 Score = 1463 bits (3787), Expect = 0.0
 Identities = 717/1091 (65%), Positives = 868/1091 (79%), Gaps = 21/1091 (1%)

Query: 13   CAGEEKRVGTRTVFVGNH-PVSETEAYIAQRFCDNRIVSSKYTLWNFLPKNLFEQFRRIA 71
            CAGEE  V +RT++VG+  P    EAYI QR+ DNRIVSSKYT WNF+PKNLFEQFRR+A
Sbjct: 14   CAGEENWVDSRTIYVGHREPPPGAEAYIPQRYPDNRIVSSKYTFWNFIPKNLFEQFRRVA 73

Query: 72   NFYFLIIFLVQVTVDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHRADNEVNKSTVYII 131
            NFYFLIIFLVQ+ +DTPTSPVTSGLPLFFVITVTAIKQGYEDWLRH+ADN +N+  V+ I
Sbjct: 74   NFYFLIIFLVQLIIDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHKADNAMNQCPVHFI 133

Query: 132  ENAKRVRKESEKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHY 191
            ++ K VRK+S K++VGD+V V+ DETFPCDLI LSS   DGTC+VTTASLDGES+ KTHY
Sbjct: 134  QHGKLVRKQSRKLRVGDIVMVKEDETFPCDLIFLSSNRGDGTCHVTTASLDGESSHKTHY 193

Query: 192  AVRDTIALCTAESIDTLRAAIECEQPQPDLYKFVGRINIYSNSLEAVARSLGPENLLLKG 251
            AV+DT    T E I  L A IECEQPQPDLYKFVGRIN+YS+  + V R LG ENLLL+G
Sbjct: 194  AVQDTKGFHTEEDIGGLHATIECEQPQPDLYKFVGRINVYSDLNDPVVRPLGSENLLLRG 253

Query: 252  ATLKNTEKIYGVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLFILLTKAAVCTT 311
            ATLKNTEKI+GVA+YTGMETKMALNYQ KSQKRSAVEKS+NAFLIVYL IL++KA + T 
Sbjct: 254  ATLKNTEKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNAFLIVYLCILISKALINTV 313

Query: 312  LKYVWQSTPYNDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKF 371
            LKY+WQS P+ DEPWYNQKT+ ER+    LK FTDFL+FMVLFN+IIPVSMYVTVEMQKF
Sbjct: 314  LKYMWQSEPFRDEPWYNQKTESERQRNLFLKAFTDFLAFMVLFNYIIPVSMYVTVEMQKF 373

Query: 372  LGSFFISWDKDFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDG 431
            LGS+FI+WD+D +DEE  EG LVNTSDLNEELGQV+Y+FTDKTGTLTEN+MEF ECCI+G
Sbjct: 374  LGSYFITWDEDMFDEETGEGPLVNTSDLNEELGQVEYIFTDKTGTLTENNMEFKECCIEG 433

Query: 432  HKY-------KGVTQEVDGLSQTDGTLTYFDKVDKNREELFLRALCLCHTVEIKTNDAVD 484
            H Y         V  E  G+   D + +      + REELF RALCLCHTV++K +D+VD
Sbjct: 434  HVYVPHVICNGQVLPESSGIDMIDSSPSV---NGREREELFFRALCLCHTVQVKDDDSVD 490

Query: 485  GATESAE----LTYISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHT 540
            G  +S +      YISSSPDE+ALV+G +R GFT+L  ++ YM + N+   IE +ELL  
Sbjct: 491  GPRKSPDGGKSCVYISSSPDEVALVEGVQRLGFTYLRLKDNYMEILNRENHIERFELLEI 550

Query: 541  LNFDAVRRRMSVIVKTQEGDILLFCKGADSAVFPRVQNHEIELTKVHVERNAMDGYRTLC 600
            L+FD+VRRRMSVIVK+  G+I LFCKGADS++FPRV   +++  +  VERNA++G RTLC
Sbjct: 551  LSFDSVRRRMSVIVKSATGEIYLFCKGADSSIFPRVIEGKVDQIRARVERNAVEGLRTLC 610

Query: 601  VAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAA 660
            VA+K +  ++YE I + L  AK+ALQDRE+K+ + ++ IE ++ L+GATAVED+LQ++AA
Sbjct: 611  VAYKRLIQEEYEGICKLLQAAKVALQDREKKLAEAYEQIEKDLTLLGATAVEDRLQEKAA 670

Query: 661  ETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERKEDRLHE 720
            +TIEAL  AG+KVWVLTGDKMETA +TCYAC+LF+ NT+LLELTTK IEE       LH+
Sbjct: 671  DTIEALQKAGIKVWVLTGDKMETAAATCYACKLFRRNTQLLELTTKRIEEQS-----LHD 725

Query: 721  LLIEYRKKLLHEFPKSTR-SFKKAWTEHQEYGLIIDGSTLSLILNSSQDSSSNNYKSIFL 779
            +L E  K +L      TR +      + Q+YGLIIDG+ LSLI+   +D SS NY+ +FL
Sbjct: 726  VLFELSKTVLRHSGSLTRDNLSGLSADMQDYGLIIDGAALSLIMKPREDGSSGNYRELFL 785

Query: 780  QICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMILESHVGIGIKGK 839
            +IC  C+AVLCCRMAPLQKAQIV+++K  K  PITL+IGDGANDVSMILE+HVGIG+ GK
Sbjct: 786  EICRSCSAVLCCRMAPLQKAQIVKLIKFSKEHPITLAIGDGANDVSMILEAHVGIGVIGK 845

Query: 840  EGRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCG 899
            EGRQAARNSDY++PKFKHLKK+LL HGH YY+RI+ LVQYFFYKN+CFI PQFLYQFFCG
Sbjct: 846  EGRQAARNSDYAIPKFKHLKKMLLVHGHFYYIRISELVQYFFYKNVCFIFPQFLYQFFCG 905

Query: 900  FSQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPRLYMKISGNAMLQLGPF 959
            FSQQ LYD AYLT+YNI FTSLPIL YSL+EQH+ ID L  DP LY  ++ NA+L+   F
Sbjct: 906  FSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLKRDPTLYRDVAKNALLRWRVF 965

Query: 960  LYWTFLAAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFGTIVFTVLVFTVTLKLALDTR 1019
            +YWT L  F+  VFFFG YF+F+  ++  NG+++GNWTFGT+VFTV+VFTVTLKLALDT 
Sbjct: 966  IYWTLLGLFDALVFFFGAYFVFENTTVTSNGQIFGNWTFGTLVFTVMVFTVTLKLALDTH 1025

Query: 1020 FWTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQQRMYFVFAQMLSSVSTWLAIILLIFI 1079
            +WTWINHFVIWGSL FYV FS  WGG+IWPFL  QRMY+VF QMLSS   WLAI+LL+ I
Sbjct: 1026 YWTWINHFVIWGSLLFYVVFSLLWGGVIWPFLNYQRMYYVFIQMLSSGPAWLAIVLLVTI 1085

Query: 1080 SLFPEILLIVL 1090
            SL P++L  VL
Sbjct: 1086 SLLPDVLKKVL 1096


>gi|150421684 ATPase, class VI, type 11A isoform a [Homo sapiens]
          Length = 1134

 Score = 1463 bits (3787), Expect = 0.0
 Identities = 717/1091 (65%), Positives = 868/1091 (79%), Gaps = 21/1091 (1%)

Query: 13   CAGEEKRVGTRTVFVGNH-PVSETEAYIAQRFCDNRIVSSKYTLWNFLPKNLFEQFRRIA 71
            CAGEE  V +RT++VG+  P    EAYI QR+ DNRIVSSKYT WNF+PKNLFEQFRR+A
Sbjct: 14   CAGEENWVDSRTIYVGHREPPPGAEAYIPQRYPDNRIVSSKYTFWNFIPKNLFEQFRRVA 73

Query: 72   NFYFLIIFLVQVTVDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHRADNEVNKSTVYII 131
            NFYFLIIFLVQ+ +DTPTSPVTSGLPLFFVITVTAIKQGYEDWLRH+ADN +N+  V+ I
Sbjct: 74   NFYFLIIFLVQLIIDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHKADNAMNQCPVHFI 133

Query: 132  ENAKRVRKESEKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHY 191
            ++ K VRK+S K++VGD+V V+ DETFPCDLI LSS   DGTC+VTTASLDGES+ KTHY
Sbjct: 134  QHGKLVRKQSRKLRVGDIVMVKEDETFPCDLIFLSSNRGDGTCHVTTASLDGESSHKTHY 193

Query: 192  AVRDTIALCTAESIDTLRAAIECEQPQPDLYKFVGRINIYSNSLEAVARSLGPENLLLKG 251
            AV+DT    T E I  L A IECEQPQPDLYKFVGRIN+YS+  + V R LG ENLLL+G
Sbjct: 194  AVQDTKGFHTEEDIGGLHATIECEQPQPDLYKFVGRINVYSDLNDPVVRPLGSENLLLRG 253

Query: 252  ATLKNTEKIYGVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLFILLTKAAVCTT 311
            ATLKNTEKI+GVA+YTGMETKMALNYQ KSQKRSAVEKS+NAFLIVYL IL++KA + T 
Sbjct: 254  ATLKNTEKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNAFLIVYLCILISKALINTV 313

Query: 312  LKYVWQSTPYNDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKF 371
            LKY+WQS P+ DEPWYNQKT+ ER+    LK FTDFL+FMVLFN+IIPVSMYVTVEMQKF
Sbjct: 314  LKYMWQSEPFRDEPWYNQKTESERQRNLFLKAFTDFLAFMVLFNYIIPVSMYVTVEMQKF 373

Query: 372  LGSFFISWDKDFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDG 431
            LGS+FI+WD+D +DEE  EG LVNTSDLNEELGQV+Y+FTDKTGTLTEN+MEF ECCI+G
Sbjct: 374  LGSYFITWDEDMFDEETGEGPLVNTSDLNEELGQVEYIFTDKTGTLTENNMEFKECCIEG 433

Query: 432  HKY-------KGVTQEVDGLSQTDGTLTYFDKVDKNREELFLRALCLCHTVEIKTNDAVD 484
            H Y         V  E  G+   D + +      + REELF RALCLCHTV++K +D+VD
Sbjct: 434  HVYVPHVICNGQVLPESSGIDMIDSSPSV---NGREREELFFRALCLCHTVQVKDDDSVD 490

Query: 485  GATESAE----LTYISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHT 540
            G  +S +      YISSSPDE+ALV+G +R GFT+L  ++ YM + N+   IE +ELL  
Sbjct: 491  GPRKSPDGGKSCVYISSSPDEVALVEGVQRLGFTYLRLKDNYMEILNRENHIERFELLEI 550

Query: 541  LNFDAVRRRMSVIVKTQEGDILLFCKGADSAVFPRVQNHEIELTKVHVERNAMDGYRTLC 600
            L+FD+VRRRMSVIVK+  G+I LFCKGADS++FPRV   +++  +  VERNA++G RTLC
Sbjct: 551  LSFDSVRRRMSVIVKSATGEIYLFCKGADSSIFPRVIEGKVDQIRARVERNAVEGLRTLC 610

Query: 601  VAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAA 660
            VA+K +  ++YE I + L  AK+ALQDRE+K+ + ++ IE ++ L+GATAVED+LQ++AA
Sbjct: 611  VAYKRLIQEEYEGICKLLQAAKVALQDREKKLAEAYEQIEKDLTLLGATAVEDRLQEKAA 670

Query: 661  ETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERKEDRLHE 720
            +TIEAL  AG+KVWVLTGDKMETA +TCYAC+LF+ NT+LLELTTK IEE       LH+
Sbjct: 671  DTIEALQKAGIKVWVLTGDKMETAAATCYACKLFRRNTQLLELTTKRIEEQS-----LHD 725

Query: 721  LLIEYRKKLLHEFPKSTR-SFKKAWTEHQEYGLIIDGSTLSLILNSSQDSSSNNYKSIFL 779
            +L E  K +L      TR +      + Q+YGLIIDG+ LSLI+   +D SS NY+ +FL
Sbjct: 726  VLFELSKTVLRHSGSLTRDNLSGLSADMQDYGLIIDGAALSLIMKPREDGSSGNYRELFL 785

Query: 780  QICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMILESHVGIGIKGK 839
            +IC  C+AVLCCRMAPLQKAQIV+++K  K  PITL+IGDGANDVSMILE+HVGIG+ GK
Sbjct: 786  EICRSCSAVLCCRMAPLQKAQIVKLIKFSKEHPITLAIGDGANDVSMILEAHVGIGVIGK 845

Query: 840  EGRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCG 899
            EGRQAARNSDY++PKFKHLKK+LL HGH YY+RI+ LVQYFFYKN+CFI PQFLYQFFCG
Sbjct: 846  EGRQAARNSDYAIPKFKHLKKMLLVHGHFYYIRISELVQYFFYKNVCFIFPQFLYQFFCG 905

Query: 900  FSQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPRLYMKISGNAMLQLGPF 959
            FSQQ LYD AYLT+YNI FTSLPIL YSL+EQH+ ID L  DP LY  ++ NA+L+   F
Sbjct: 906  FSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLKRDPTLYRDVAKNALLRWRVF 965

Query: 960  LYWTFLAAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFGTIVFTVLVFTVTLKLALDTR 1019
            +YWT L  F+  VFFFG YF+F+  ++  NG+++GNWTFGT+VFTV+VFTVTLKLALDT 
Sbjct: 966  IYWTLLGLFDALVFFFGAYFVFENTTVTSNGQIFGNWTFGTLVFTVMVFTVTLKLALDTH 1025

Query: 1020 FWTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQQRMYFVFAQMLSSVSTWLAIILLIFI 1079
            +WTWINHFVIWGSL FYV FS  WGG+IWPFL  QRMY+VF QMLSS   WLAI+LL+ I
Sbjct: 1026 YWTWINHFVIWGSLLFYVVFSLLWGGVIWPFLNYQRMYYVFIQMLSSGPAWLAIVLLVTI 1085

Query: 1080 SLFPEILLIVL 1090
            SL P++L  VL
Sbjct: 1086 SLLPDVLKKVL 1096


>gi|62632750 ATPase, class VI, type 11B [Homo sapiens]
          Length = 1177

 Score = 1207 bits (3124), Expect = 0.0
 Identities = 611/1105 (55%), Positives = 788/1105 (71%), Gaps = 74/1105 (6%)

Query: 22   TRTVFVGNHPVSETEAYIAQRFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLV 81
            TRT++V N    +   Y  Q+F DNRI+SSKYT+WNF+PKNLFEQFRR+ANFYFLIIFLV
Sbjct: 19   TRTIYVANR-FPQNGLYTPQKFIDNRIISSKYTVWNFVPKNLFEQFRRVANFYFLIIFLV 77

Query: 82   QVTVDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHRADNEVNKSTVYIIENAKRVRKES 141
            Q+ +DTPTSPVTSGLPLFFVITVTAIKQGYEDWLRH +DNEVN + VY++ +   V+  S
Sbjct: 78   QLMIDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHNSDNEVNGAPVYVVRSGGLVKTRS 137

Query: 142  EKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIALCT 201
            + I+VGD+V +  DE FP DL+LLSS   DG+C+VTTASLDGE+N KTH AV +T  L T
Sbjct: 138  KNIRVGDIVRIAKDEIFPADLVLLSSDRLDGSCHVTTASLDGETNLKTHVAVPETALLQT 197

Query: 202  AESIDTLRAAIECEQPQPDLYKFVGRINIYSNSLEAVARSLGPENLLLKGATLKNTEKIY 261
              ++DTL A IEC+QP+ DLY+F+GR+ I +  +E + R LGPE+LLL+GA LKNT++I+
Sbjct: 198  VANLDTLVAVIECQQPEADLYRFMGRM-IITQQMEEIVRPLGPESLLLRGARLKNTKEIF 256

Query: 262  GVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLFILLTKAAVCTTLKYVWQSTPY 321
            GVAVYTGMETKMALNY+ KSQKRSAVEKS+N FLI+YL IL+++A + T LKY WQ+   
Sbjct: 257  GVAVYTGMETKMALNYKSKSQKRSAVEKSMNTFLIIYLVILISEAVISTILKYTWQAEEK 316

Query: 322  NDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFISWDK 381
             DEPWYNQKT+ +R + K+L+  +DFL+F+VL+NFIIP+S+YVTVEMQKFLGSFFI WD 
Sbjct: 317  WDEPWYNQKTEHQRNSSKILRFISDFLAFLVLYNFIIPISLYVTVEMQKFLGSFFIGWDL 376

Query: 382  DFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKYKGVTQEV 441
            D Y EE ++ A VNTSDLNEELGQV+YVFTDKTGTLTEN M+F EC I+G KY    QE+
Sbjct: 377  DLYHEESDQKAQVNTSDLNEELGQVEYVFTDKTGTLTENEMQFRECSINGMKY----QEI 432

Query: 442  DGL--------SQTDGTLTYFDKVDK------------------------NREELFLRAL 469
            +G           ++G L+Y   +                             +LF +A+
Sbjct: 433  NGRLVPEGPTPDSSEGNLSYLSSLSHLNNLSHLTTSSSFRTSPENETELIKEHDLFFKAV 492

Query: 470  CLCHTVEI---KTNDAVDGATES----AELTYISSSPDEIALVKGAKRYGFTFLGNRNGY 522
             LCHTV+I   +T+   DG  +S    ++L Y +SSPDE ALV+ A R G  F+GN    
Sbjct: 493  SLCHTVQISNVQTDCTGDGPWQSNLAPSQLEYYASSPDEKALVEAAARIGIVFIGNSEET 552

Query: 523  MRVENQRKEIEEYELLHTLNFDAVRRRMSVIVKTQEGDILLFCKGADSAVFPRVQNHEIE 582
            M V+   K +E Y+LLH L FD+ RRRMSVIV+   G+ LLF KGA+S++ P+    EIE
Sbjct: 553  MEVKTLGK-LERYKLLHILEFDSDRRRMSVIVQAPSGEKLLFAKGAESSILPKCIGGEIE 611

Query: 583  LTKVHVERNAMDGYRTLCVAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETN 642
             T++HV+  A+ G RTLC+A+++    +YE I++++ EA+ ALQ REEK+  VF  IE +
Sbjct: 612  KTRIHVDEFALKGLRTLCIAYRKFTSKEYEEIDKRIFEARTALQQREEKLAAVFQFIEKD 671

Query: 643  MNLIGATAVEDKLQDQAAETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLE 702
            + L+GATAVED+LQD+  ETIEAL  AG+KVWVLTGDK ETA S   +C  F     +LE
Sbjct: 672  LILLGATAVEDRLQDKVRETIEALRMAGIKVWVLTGDKHETAVSVSLSCGHFHRTMNILE 731

Query: 703  LTTKTIEESERKEDRLHELLIEYRKKLLHEFPKSTRSFKKAWTEHQEYGLIIDGSTLSLI 762
            L       +++ +    E L +  +++  +                ++GL++DG++LSL 
Sbjct: 732  LI------NQKSDSECAEQLRQLARRITED-------------HVIQHGLVVDGTSLSLA 772

Query: 763  LNSSQDSSSNNYKSIFLQICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGAN 822
            L          ++ +F+++C  C+AVLCCRMAPLQKA+++R++K     PITL++GDGAN
Sbjct: 773  L--------REHEKLFMEVCRNCSAVLCCRMAPLQKAKVIRLIKISPEKPITLAVGDGAN 824

Query: 823  DVSMILESHVGIGIKGKEGRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFY 882
            DVSMI E+HVGIGI GKEGRQAARNSDY++ +FK L KLL  HGH YY+RIA LVQYFFY
Sbjct: 825  DVSMIQEAHVGIGIMGKEGRQAARNSDYAIARFKFLSKLLFVHGHFYYIRIATLVQYFFY 884

Query: 883  KNLCFILPQFLYQFFCGFSQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDP 942
            KN+CFI PQFLYQF+C FSQQ LYD+ YLT+YNICFTSLPIL YSLLEQH++   L + P
Sbjct: 885  KNVCFITPQFLYQFYCLFSQQTLYDSVYLTLYNICFTSLPILIYSLLEQHVDPHVLQNKP 944

Query: 943  RLYMKISGNAMLQLGPFLYWTFLAAFEGTVFFFGTYFLF-QTASLEENGKVYGNWTFGTI 1001
             LY  IS N +L +  FLYWT L      +FFFG+Y L  +  SL  NG+++GNWTFGT+
Sbjct: 945  TLYRDISKNRLLSIKTFLYWTILGFSHAFIFFFGSYLLIGKDTSLLGNGQMFGNWTFGTL 1004

Query: 1002 VFTVLVFTVTLKLALDTRFWTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQQRMYFVFA 1061
            VFTV+V TVT+K+AL+T FWTWINH V WGS+ FY  FS F+GGI+WPFL  Q MYFVF 
Sbjct: 1005 VFTVMVITVTVKMALETHFWTWINHLVTWGSIIFYFVFSLFYGGILWPFLGSQNMYFVFI 1064

Query: 1062 QMLSSVSTWLAIILLIFISLFPEIL 1086
            Q+LSS S W AIIL++   LF +I+
Sbjct: 1065 QLLSSGSAWFAIILMVVTCLFLDII 1089


>gi|157649069 ATPase, aminophospholipid transporter (APLT), class I,
            type 8A, member 1 isoform b [Homo sapiens]
          Length = 1149

 Score =  662 bits (1707), Expect = 0.0
 Identities = 387/1080 (35%), Positives = 595/1080 (55%), Gaps = 69/1080 (6%)

Query: 23   RTVFVGNHPVSETEAYIAQRFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLVQ 82
            RT+F+    ++        +FC+N + ++KY +  FLP+ L+ QFRR AN +FL I L+Q
Sbjct: 37   RTIFINQPQLT--------KFCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQ 88

Query: 83   VTVD-TPTSPVTSGLPLFFVITVTAIKQGYEDWLRHRADNEVNKSTVYIIENAKRVRKES 141
               D +PT   T+ +PL F++ V AIK+  ED  RH+ADN VNK    ++ N        
Sbjct: 89   QIPDVSPTGRYTTLVPLLFILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVHW 148

Query: 142  EKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIALCT 201
            EK+ VGD+V ++  E  P D +LLSS      CY+ T++LDGE+N K    +  T  +  
Sbjct: 149  EKVNVGDIVIIKGKEYIPADTVLLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKD 208

Query: 202  AESIDTLRAAIECEQPQPDLYKFVGRINIYSNSLEAVARSLGPENLLLKGATLKNTEKIY 261
             +S+  +   IECE P   LY FVG I +  +        LG + +LL+GA L+NT+ ++
Sbjct: 209  VDSLMRISGRIECESPNRHLYDFVGNIRLDGHGTVP----LGADQILLRGAQLRNTQWVH 264

Query: 262  GVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLFILLTKAAVCTTLKYVWQSTPY 321
            G+ VYTG +TK+  N      K S VE+  N  +++   IL+  + VC+    +W    +
Sbjct: 265  GIVVYTGHDTKLMQNSTSPPLKLSNVERITNVQILILFCILIAMSLVCSVGSAIWNRR-H 323

Query: 322  NDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFISWDK 381
            + + WY            +     +FL+F++LFN +IP+S+ VT+E+ KF  ++FI+WD 
Sbjct: 324  SGKDWYLNLNYGGASNFGL-----NFLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDL 378

Query: 382  DFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKYKGVTQEV 441
            D + E  +  A+  TS+LNEELGQV Y+F+DKTGTLT N M+F +C I G  Y   +Q  
Sbjct: 379  DMHYEPTDTAAMARTSNLNEELGQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGQNSQFG 438

Query: 442  DGLSQTDGTLTYFDKVDKNREEL-----FLRALCLCHTVEIKTNDAVDGATESAELTYIS 496
            D  + +D +L   + +  N         FL  + +CHT   +         E  ++ Y +
Sbjct: 439  DEKTFSDSSL--LENLQNNHPTAPIICEFLTMMAVCHTAVPER--------EGDKIIYQA 488

Query: 497  SSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRRRMSVIVKT 556
            +SPDE ALV+ AK+  F F G     + +++  +E E YELL+ L F + R+RMSVIV+T
Sbjct: 489  ASPDEGALVRAAKQLNFVFTGRTPDSVIIDSLGQE-ERYELLNVLEFTSARKRMSVIVRT 547

Query: 557  QEGDILLFCKGADSAVFPRVQNHEI--ELTKVHVERNAMDGYRTLCVAFKEIAPDDYERI 614
              G + L+CKGAD+ ++ R+       E+T  H+E+ A +G RTLC A  EI+  D++  
Sbjct: 548  PSGKLRLYCKGADTVIYDRLAETSKYKEITLKHLEQFATEGLRTLCFAVAEISESDFQEW 607

Query: 615  NRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAAETIEALHAAGLKVW 674
                  A  ++Q+R  K+E+ ++ IE N+ L+GATA+EDKLQDQ  ETIE L  A +K+W
Sbjct: 608  RAVYQRASTSVQNRLLKLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIKIW 667

Query: 675  VLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERKEDRLHELLIEYRKKLLHEFP 734
            +LTGDK ETA +  ++C+L + N  ++ +   +++ +     R    L +  +K      
Sbjct: 668  ILTGDKQETAINIGHSCKLLKKNMGMIVINEGSLDGTRETLSRHCTTLGDALRK------ 721

Query: 735  KSTRSFKKAWTEHQEYGLIIDGSTLSLILNSSQDSSSNNYKSIFLQICMKCTAVLCCRMA 794
                          ++ LIIDG TL   L           +  FL + + C AV+CCR++
Sbjct: 722  ------------ENDFALIIDGKTLKYALTFG-------VRQYFLDLALSCKAVICCRVS 762

Query: 795  PLQKAQIVRMVKNLKGSPITLSIGDGANDVSMILESHVGIGIKGKEGRQAARNSDYSVPK 854
            PLQK+++V MVK  +   +TL+IGDGANDVSMI  +HVG+GI G EG QAA +SDYS+ +
Sbjct: 763  PLQKSEVVEMVKK-QVKVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQ 821

Query: 855  FKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCGFSQQPLYDAAYLTMY 914
            FK+LK LL+ HG   Y R++  + Y FYKN+   + +  + F  GFS Q L++   + +Y
Sbjct: 822  FKYLKNLLMIHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLY 881

Query: 915  NICFTSLPILAYSLLEQHINIDTLTSDPRLYMKISGNAMLQLGPFLYWTFL--AAFEGTV 972
            N+ FT++P L   + E+    + +   P LY K S NA L     ++W       F   +
Sbjct: 882  NVMFTAMPPLTLGIFERSCRKENMLKYPELY-KTSQNA-LDFNTKVFWVHCLNGLFHSVI 939

Query: 973  FFFGTYFLFQTASLEENGKVYGNWTFGTIVFTVLVFTVTLKLALDTRFWTWINHFVIWGS 1032
             F+      Q  +   NGK       G  V+T +V TV LK  L+T +WTW +H  IWGS
Sbjct: 940  LFWFPLKALQYGTAFGNGKTSDYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWGS 999

Query: 1033 LAFYVFFSFFWGGIIWPFLKQ-QRMYFVFAQMLSSVSTWLAIILLIFISLFPEILLIVLK 1091
            +A +V F   +   +WP +     M    A + SS   W+ ++ +   SL  +++  V+K
Sbjct: 1000 IALWVVFFGIYSS-LWPAIPMAPDMSGEAAMLFSSGVFWMGLLFIPVASLLLDVVYKVIK 1058


>gi|17978471 ATPase, aminophospholipid transporter (APLT), class I,
            type 8A, member 1 isoform a [Homo sapiens]
          Length = 1164

 Score =  656 bits (1693), Expect = 0.0
 Identities = 388/1093 (35%), Positives = 594/1093 (54%), Gaps = 80/1093 (7%)

Query: 23   RTVFVGNHPVSETEAYIAQRFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLVQ 82
            RT+F+    ++        +FC+N + ++KY +  FLP+ L+ QFRR AN +FL I L+Q
Sbjct: 37   RTIFINQPQLT--------KFCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQ 88

Query: 83   VTVD-TPTSPVTSGLPLFFVITVTAIKQGYEDWLRHRADNEVNKSTVYIIENAKRVRKES 141
               D +PT   T+ +PL F++ V AIK+  ED  RH+ADN VNK    ++ N        
Sbjct: 89   QIPDVSPTGRYTTLVPLLFILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVHW 148

Query: 142  EKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIALCT 201
            EK+ VG++V+V   E  P DLI LSS      CY+ T++LDGE+N K    +  T  +  
Sbjct: 149  EKVAVGEIVKVTNGEHLPADLISLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKD 208

Query: 202  AESIDTLRAAIECEQPQPDLYKFVGRINIYSNSLEAVARSLGPENLLLKGATLKNTEKIY 261
             +S+  +   IECE P   LY FVG I +  +        LG + +LL+GA L+NT+ ++
Sbjct: 209  VDSLMRISGRIECESPNRHLYDFVGNIRLDGHGTVP----LGADQILLRGAQLRNTQWVH 264

Query: 262  GVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLFILLTKAAVCTTLKYVWQSTPY 321
            G+ VYTG +TK+  N      K S VE+  N  +++   IL+  + VC+    +W    +
Sbjct: 265  GIVVYTGHDTKLMQNSTSPPLKLSNVERITNVQILILFCILIAMSLVCSVGSAIWNRR-H 323

Query: 322  NDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFISWDK 381
            + + WY            +     +FL+F++LFN +IP+S+ VT+E+ KF  ++FI+WD 
Sbjct: 324  SGKDWYLNLNYGGASNFGL-----NFLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDL 378

Query: 382  DFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKYKGVTQEV 441
            D + E  +  A+  TS+LNEELGQV Y+F+DKTGTLT N M+F +C I G  Y  V +  
Sbjct: 379  DMHYEPTDTAAMARTSNLNEELGQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGHVPEPE 438

Query: 442  D-------------GLSQTDGTLTYFDKVDKNREEL-----FLRALCLCHTVEIKTNDAV 483
            D             G  +T    +  + +  N         FL  + +CHT   +     
Sbjct: 439  DYGCSPDEWQNSQFGDEKTFSDSSLLENLQNNHPTAPIICEFLTMMAVCHTAVPER---- 494

Query: 484  DGATESAELTYISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNF 543
                E  ++ Y ++SPDE ALV+ AK+  F F G     + +++  +E E YELL+ L F
Sbjct: 495  ----EGDKIIYQAASPDEGALVRAAKQLNFVFTGRTPDSVIIDSLGQE-ERYELLNVLEF 549

Query: 544  DAVRRRMSVIVKTQEGDILLFCKGADSAVFPRVQNHEI--ELTKVHVERNAMDGYRTLCV 601
             + R+RMSVIV+T  G + L+CKGAD+ ++ R+       E+T  H+E+ A +G RTLC 
Sbjct: 550  TSARKRMSVIVRTPSGKLRLYCKGADTVIYDRLAETSKYKEITLKHLEQFATEGLRTLCF 609

Query: 602  AFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAAE 661
            A  EI+  D++        A  ++Q+R  K+E+ ++ IE N+ L+GATA+EDKLQDQ  E
Sbjct: 610  AVAEISESDFQEWRAVYQRASTSVQNRLLKLEESYELIEKNLQLLGATAIEDKLQDQVPE 669

Query: 662  TIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERKEDRLHEL 721
            TIE L  A +K+W+LTGDK ETA +  ++C+L + N  ++ +   +++ +     R    
Sbjct: 670  TIETLMKADIKIWILTGDKQETAINIGHSCKLLKKNMGMIVINEGSLDGTRETLSRHCTT 729

Query: 722  LIEYRKKLLHEFPKSTRSFKKAWTEHQEYGLIIDGSTLSLILNSSQDSSSNNYKSIFLQI 781
            L +  +K                    ++ LIIDG TL   L           +  FL +
Sbjct: 730  LGDALRK------------------ENDFALIIDGKTLKYALTFG-------VRQYFLDL 764

Query: 782  CMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMILESHVGIGIKGKEG 841
             + C AV+CCR++PLQK+++V MVK  +   +TL+IGDGANDVSMI  +HVG+GI G EG
Sbjct: 765  ALSCKAVICCRVSPLQKSEVVEMVKK-QVKVVTLAIGDGANDVSMIQTAHVGVGISGNEG 823

Query: 842  RQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCGFS 901
             QAA +SDYS+ +FK+LK LL+ HG   Y R++  + Y FYKN+   + +  + F  GFS
Sbjct: 824  LQAANSSDYSIAQFKYLKNLLMIHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFS 883

Query: 902  QQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPRLYMKISGNAMLQLGPFLY 961
             Q L++   + +YN+ FT++P L   + E+    + +   P LY K S NA L     ++
Sbjct: 884  GQILFERWCIGLYNVMFTAMPPLTLGIFERSCRKENMLKYPELY-KTSQNA-LDFNTKVF 941

Query: 962  WTFL--AAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFGTIVFTVLVFTVTLKLALDTR 1019
            W       F   + F+      Q  +   NGK       G  V+T +V TV LK  L+T 
Sbjct: 942  WVHCLNGLFHSVILFWFPLKALQYGTAFGNGKTSDYLLLGNFVYTFVVITVCLKAGLETS 1001

Query: 1020 FWTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQ-QRMYFVFAQMLSSVSTWLAIILLIF 1078
            +WTW +H  IWGS+A +V F   +   +WP +     M    A + SS   W+ ++ +  
Sbjct: 1002 YWTWFSHIAIWGSIALWVVFFGIYSS-LWPAIPMAPDMSGEAAMLFSSGVFWMGLLFIPV 1060

Query: 1079 ISLFPEILLIVLK 1091
             SL  +++  V+K
Sbjct: 1061 ASLLLDVVYKVIK 1073


>gi|40316837 ATPase, class I, type 8B, member 2 isoform a [Homo
            sapiens]
          Length = 1223

 Score =  634 bits (1634), Expect = 0.0
 Identities = 372/1088 (34%), Positives = 581/1088 (53%), Gaps = 65/1088 (5%)

Query: 42   RFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLVQVTVDTPT-SPVTSGLPLFF 100
            ++  N I +SKY +  FLP NLFEQF+ +AN YFL + ++Q+     + S  T+ +PL  
Sbjct: 61   QYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVL 120

Query: 101  VITVTAIKQGYEDWLRHRADNEVNKSTVYIIENAKRVRKESEKIKVGDVVEVQADETFPC 160
            V+T+TA+K   +D+ RH++DN+VN     ++ N    +++   + VGD+++++ ++    
Sbjct: 121  VLTITAVKDATDDYFRHKSDNQVNNRQSQVLINGILQQEQWMNVCVGDIIKLENNQFVAA 180

Query: 161  DLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIALCTAESIDTLRAAIECEQPQPD 220
            DL+LLSS    G CY+ TA LDGE+N K   A+  T  L     +      + CE P   
Sbjct: 181  DLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGDISKLAKFDGEVICEPPNNK 240

Query: 221  LYKFVGRINIYSNSLEAVARSLGPENLLLKGATLKNTEKIYGVAVYTGMETKMALNYQGK 280
            L KF G +    N        L  +N+LL+G  L+NTE  +G+ ++ G +TK+  N    
Sbjct: 241  LDKFSGTLYWKENKFP-----LSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRT 295

Query: 281  SQKRSAVEKSINAFLIVYLFILLTKAAVCTTLKYVWQSTPYNDE----PWYNQKTQKERE 336
              KR+++++ +N  ++     L+    +      +W+           PW       E  
Sbjct: 296  KFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGMRFQVYLPW------DEAV 349

Query: 337  TLKVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFISWDKDFYDEEINEGALVNT 396
                   F  F S++++ N ++P+S+YV+VE+ +   S+FI+WDK  +  +    A   T
Sbjct: 350  DSAFFSGFLSFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDKKMFCMKKRTPAEART 409

Query: 397  SDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKYKGVTQEVDGLSQ---------- 446
            + LNEELGQV+Y+F+DKTGTLT+N M F +C I+GH Y  V   +   ++          
Sbjct: 410  TTLNEELGQVEYIFSDKTGTLTQNIMVFNKCSINGHSYGDVFDVLGHKAELGERPEPVDF 469

Query: 447  -----TDGTLTYFD-------KVDKNREELFLRALCLCHTVEIKTNDAVDGATESAELTY 494
                  D    ++D       K+       F R L LCHTV  +  +         EL Y
Sbjct: 470  SFNPLADKKFLFWDPSLLEAVKIGDPHTHEFFRLLSLCHTVMSEEKN-------EGELYY 522

Query: 495  ISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRRRMSVIV 554
             + SPDE ALV  A+ +GF F       + V      I  Y+LL  L+F+ +R+RMSVIV
Sbjct: 523  KAQSPDEGALVTAARNFGFVFRSRTPKTITVHEMGTAIT-YQLLAILDFNNIRKRMSVIV 581

Query: 555  KTQEGDILLFCKGADSAVFPRVQNHEIEL---TKVHVERNAMDGYRTLCVAFKEIAPDDY 611
            +  EG I L+CKGAD+ +  R+ +   EL   T  H+   A +G RTL +A+K++  + Y
Sbjct: 582  RNPEGKIRLYCKGADTILLDRLHHSTQELLNTTMDHLNEYAGEGLRTLVLAYKDLDEEYY 641

Query: 612  ERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAAETIEALHAAGL 671
            E    + ++A +A   RE+++  +++++E NM L+GATA+EDKLQ    ETI  L  A +
Sbjct: 642  EEWAERRLQASLAQDSREDRLASIYEEVENNMMLLGATAIEDKLQQGVPETIALLTLANI 701

Query: 672  KVWVLTGDKMETAKSTCYACRLFQTN-TELLELTTKTIEESERKEDRLHELLIEYRKKLL 730
            K+WVLTGDK ETA +  Y+C++   + TE+  +T  T+ E   +  +  E +++  + + 
Sbjct: 702  KIWVLTGDKQETAVNIGYSCKMLTDDMTEVFIVTGHTVLEVREELRKAREKMMDSSRSVG 761

Query: 731  HEFPKSTRSFKKAWTE-----HQEYGLIIDGSTLSLILNSSQDSSSNNYKSIFLQICMKC 785
            + F    +      T        EY L+I+G +L+  L +  +         FL+    C
Sbjct: 762  NGFTYQDKLSSSKLTSVLEAVAGEYALVINGHSLAHALEADMELE-------FLETACAC 814

Query: 786  TAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMILESHVGIGIKGKEGRQAA 845
             AV+CCR+ PLQKAQ+V +VK  K + +TL+IGDGANDVSMI  +H+G+GI G+EG QA 
Sbjct: 815  KAVICCRVTPLQKAQVVELVKKYKKA-VTLAIGDGANDVSMIKTAHIGVGISGQEGIQAV 873

Query: 846  RNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCGFSQQPL 905
              SDYS  +FK L++LLL HG   Y+R+   + YFFYKN  F +  F + FFCGFS Q +
Sbjct: 874  LASDYSFSQFKFLQRLLLVHGRWSYLRMCKFLCYFFYKNFAFTMVHFWFGFFCGFSAQTV 933

Query: 906  YDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPRLYMKISGNAMLQLGPFLYWTFL 965
            YD  ++T+YNI +TSLP+LA  + +Q +        P+LY     N +     F      
Sbjct: 934  YDQYFITLYNIVYTSLPVLAMGVFDQDVPEQRSMEYPKLYEPGQLNLLFNKREFFICIAQ 993

Query: 966  AAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFGTIVFTVLVFTVTLKLALDTRFWTWIN 1025
              +   + FF  Y +F  A+ ++  ++    +F   V T LV  V++++ LDT +WT IN
Sbjct: 994  GIYTSVLMFFIPYGVFADATRDDGTQLADYQSFAVTVATSLVIVVSVQIGLDTGYWTAIN 1053

Query: 1026 HFVIWGSLAFY--VFFSFFWGGIIWPFLKQQRMYFVFAQMLSSVSTWLAIILLIFISLFP 1083
            HF IWGSLA Y  + F+    G+   F  Q R        L+  + WL I+L   + + P
Sbjct: 1054 HFFIWGSLAVYFAILFAMHSNGLFDMFPNQFRFVGNAQNTLAQPTVWLTIVLTTVVCIMP 1113

Query: 1084 EILLIVLK 1091
             +    L+
Sbjct: 1114 VVAFRFLR 1121


>gi|50083277 ATPase class I type 8B member 4 [Homo sapiens]
          Length = 1192

 Score =  633 bits (1633), Expect = 0.0
 Identities = 387/1133 (34%), Positives = 597/1133 (52%), Gaps = 83/1133 (7%)

Query: 42   RFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLVQVTVDTPTSP-VTSGLPLFF 100
            ++ DNRI +SKY +  FLP NLFEQF+R+AN YFL + ++Q+  +  +    T+ +PL  
Sbjct: 27   QYADNRIHTSKYNILTFLPINLFEQFQRVANAYFLCLLILQLIPEISSLTWFTTIVPLVL 86

Query: 101  VITVTAIKQGYEDWLRHRADNEVNKSTVYIIENAKRVRKESEKIKVGDVVEVQADETFPC 160
            VIT+TA+K   +D+ RH++DN+VN     ++ N+K   ++   +KVGD+++++ ++    
Sbjct: 87   VITMTAVKDATDDYFRHKSDNQVNNRQSEVLINSKLQNEKWMNVKVGDIIKLENNQFVAA 146

Query: 161  DLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIAL-CTAESIDTLRAAIECEQPQP 219
            DL+LLSS    G CYV TA LDGE+N K  +A+  T  L      +      + CE P  
Sbjct: 147  DLLLLSSSEPHGLCYVETAELDGETNLKVRHALSVTSELGADISRLAGFDGIVVCEVPNN 206

Query: 220  DLYKFVGRINIYSNSLEAVARSLGPENLLLKGATLKNTEKIYGVAVYTGMETKMALNYQG 279
             L KF+G +     S +    SL  E ++L+G  L+NT   +G+ ++ G +TK+  N   
Sbjct: 207  KLDKFMGIL-----SWKDSKHSLNNEKIILRGCILRNTSWCFGMVIFAGPDTKLMQNSGK 261

Query: 280  KSQKRSAVEKSINAFLIVYLFILLTKAAVCTTLKYVWQSTPYNDEPWYNQKTQKERETLK 339
               KR+++++ +N  ++     L+    +      +W+S     + +       E E   
Sbjct: 262  TKFKRTSIDRLMNTLVLWIFGFLICLGIILAIGNSIWESQ--TGDQFRTFLFWNEGEKSS 319

Query: 340  VLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFISWDKDFYDEEINEGALVNTSDL 399
            V   F  F S++++ N ++P+S+YV+VE+ +   S+FI+WD+  Y       A+  T+ L
Sbjct: 320  VFSGFLTFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDRKMYYSRKAIPAVARTTTL 379

Query: 400  NEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKYKGVTQEVDG---------------L 444
            NEELGQ++Y+F+DKTGTLT+N M F  C I+G  Y  V  ++D                 
Sbjct: 380  NEELGQIEYIFSDKTGTLTQNIMTFKRCSINGRIYGEVHDDLDQKTEITQEKEPVDFSVK 439

Query: 445  SQTDGTLTYFD-------KVDKNREELFLRALCLCHTVEIKTNDAVDGATESAELTYISS 497
            SQ D    +FD       K+   +   FLR L LCHTV  + N A        EL Y   
Sbjct: 440  SQADREFQFFDHHLMESIKMGDPKVHEFLRLLALCHTVMSEENSA-------GELIYQVQ 492

Query: 498  SPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRRRMSVIVKTQ 557
            SPDE ALV  A+ +GF F       + +E +   +  Y+LL  L+F+  R+RMSVIV+  
Sbjct: 493  SPDEGALVTAARNFGFIFKSRTPETITIE-ELGTLVTYQLLAFLDFNNTRKRMSVIVRNP 551

Query: 558  EGDILLFCKGADSAVFPRVQNHE---IELTKVHVERNAMDGYRTLCVAFKEIAPDDYERI 614
            EG I L+ KGAD+ +F ++       + LT  H+   A +G RTL +A++++    ++  
Sbjct: 552  EGQIKLYSKGADTILFEKLHPSNEVLLSLTSDHLSEFAGEGLRTLAIAYRDLDDKYFKEW 611

Query: 615  NRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAAETIEALHAAGLKVW 674
            ++ L +A  A ++R+E++  ++++IE ++ L+GATAVEDKLQ+   ET+ +L  A +K+W
Sbjct: 612  HKMLEDANAATEERDERIAGLYEEIERDLMLLGATAVEDKLQEGVIETVTSLSLANIKIW 671

Query: 675  VLTGDKMETAKSTCYACRLF--QTNTELLELTTKTIEESERKEDRLHELLIEYR------ 726
            VLTGDK ETA +  YAC +     N   +      +E  E        L  + R      
Sbjct: 672  VLTGDKQETAINIGYACNMLTDDMNDVFVIAGNNAVEVREELRKAKQNLFGQNRNFSNGH 731

Query: 727  ----KKLLHEFPKSTRSFKKAWTEHQEYGLIIDGSTLSLILNSSQDSSSNNYKSIFLQIC 782
                KK   E            T   +Y LII+G +L+  L S       + K+  L++ 
Sbjct: 732  VVCEKKQQLELDSIVEE-----TITGDYALIINGHSLAHALES-------DVKNDLLELA 779

Query: 783  MKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMILESHVGIGIKGKEGR 842
              C  V+CCR+ PLQKAQ+V +VK  + + +TL+IGDGANDVSMI  +H+G+GI G+EG 
Sbjct: 780  CMCKTVICCRVTPLQKAQVVELVKKYRNA-VTLAIGDGANDVSMIKSAHIGVGISGQEGL 838

Query: 843  QAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCGFSQ 902
            QA   SDYS  +F++L++LLL HG   Y R+   + YFFYKN  F L  F + FFCGFS 
Sbjct: 839  QAVLASDYSFAQFRYLQRLLLVHGRWSYFRMCKFLCYFFYKNFAFTLVHFWFGFFCGFSA 898

Query: 903  QPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPRLYMKISGNAMLQLGPFLYW 962
            Q +YD  ++T++NI +TSLP+LA  + +Q ++       P+LY     N +     F   
Sbjct: 899  QTVYDQWFITLFNIVYTSLPVLAMGIFDQDVSDQNSVDCPQLYKPGQLNLLFNKRKFFIC 958

Query: 963  TFLAAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFGTIVFTVLVFTVTLKLALDTRFWT 1022
                 +   V FF  Y  F   + E+   +    +F   + T LV  V++++ALDT +WT
Sbjct: 959  VLHGIYTSLVLFFIPYGAFYNVAGEDGQHIADYQSFAVTMATSLVIVVSVQIALDTSYWT 1018

Query: 1023 WINHFVIWGSLAFY--VFFSFFWGGIIWPFLKQQRMYFVFAQMLSSVSTWLAIILLIFIS 1080
            +INH  IWGS+A Y  + F+    GI   F  Q          L+    WL I+L    S
Sbjct: 1019 FINHVFIWGSIAIYFSILFTMHSNGIFGIFPNQFPFVGNARHSLTQKCIWLVILLTTVAS 1078

Query: 1081 LFPEILLIVLK---------NVRR-----RSARNPNLELPMLLSYKHTDSGYS 1119
            + P +    LK          +RR     + AR P+   P         SGY+
Sbjct: 1079 VMPVVAFRFLKVDLYPTLSDQIRRWQKAQKKARPPSSRRPRTRRSSSRRSGYA 1131


>gi|117168245 ATPase, aminophospholipid transporter-like, Class I,
            type 8A, member 2 [Homo sapiens]
          Length = 1188

 Score =  622 bits (1605), Expect = e-178
 Identities = 392/1107 (35%), Positives = 586/1107 (52%), Gaps = 79/1107 (7%)

Query: 15   GEEKRVGTRTVFVGNHPVSETEAYIAQRFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFY 74
            G++     RT+++    ++        +F DN+I ++KY++  FLP+ L+EQ RR AN +
Sbjct: 48   GDQLEAPARTIYLNQPHLN--------KFRDNQISTAKYSVLTFLPRFLYEQIRRAANAF 99

Query: 75   FLIIFLVQVTVD-TPTSPVTSGLPLFFVITVTAIKQGYEDWLRHRADNEVNKSTVYIIEN 133
            FL I L+Q   D +PT   T+ +PL  ++T+  IK+  ED+ RH+ADN VNK    ++ N
Sbjct: 100  FLFIALLQQIPDVSPTGRYTTLVPLIIILTIAGIKEIVEDFKRHKADNAVNKKKTIVLRN 159

Query: 134  AKRVRKESEKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHYAV 193
                    +++ VGD+V+V   +  P D++LLSS      CYV TA+LDGE+N K    +
Sbjct: 160  GMWHTIMWKEVAVGDIVKVVNGQYLPADVVLLSSSEPQAMCYVETANLDGETNLKIRQGL 219

Query: 194  RDTIALCTAESIDTLRAAIECEQPQPDLYKFVGRINIYSNSLEAVARSLGPENLLLKGAT 253
              T  + T E +  L   IECE P   LY F G +N+   SL A    LGP+ +LL+G  
Sbjct: 220  SHTADMQTREVLMKLSGTIECEGPNRHLYDFTGNLNLDGKSLVA----LGPDQILLRGTQ 275

Query: 254  LKNTEKIYGVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLFILLTKAAVCTTLK 313
            L+NT+ ++G+ VYTG +TK+  N      KRS VEK  N  ++V   ILL  A V +   
Sbjct: 276  LRNTQWVFGIVVYTGHDTKLMQNSTKAPLKRSNVEKVTNVQILVLFGILLVMALVSSAGA 335

Query: 314  YVWQSTPYNDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLG 373
              W  + + ++ WY +K     +         + L+F++L+N +IP+S+ VT+E+ K+  
Sbjct: 336  LYWNRS-HGEKNWYIKKMDTTSDNFGY-----NLLTFIILYNNLIPISLLVTLEVVKYTQ 389

Query: 374  SFFISWDKDFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHK 433
            + FI+WD D Y    +  A+  TS+LNEELGQV Y+F+DKTGTLT N M F +C I G  
Sbjct: 390  ALFINWDTDMYYIGNDTPAMARTSNLNEELGQVKYLFSDKTGTLTCNIMNFKKCSIAGVT 449

Query: 434  YKGVTQEVDGLSQTD--------GTLTYFD--KVDKNREEL---------FLRALCLCHT 474
            Y    +     S  D             FD  ++ KN E+          FL  L +CHT
Sbjct: 450  YGHFPELAREPSSDDFCRMPPPCSDSCDFDDPRLLKNIEDRHPTAPCIQEFLTLLAVCHT 509

Query: 475  VEIKTNDAVDGATESAELTYISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEE 534
            V  +         +   + Y +SSPDE ALVKGAK+ GF F       + +E   +E + 
Sbjct: 510  VVPE--------KDGDNIIYQASSPDEAALVKGAKKLGFVFTARTPFSVIIEAMGQE-QT 560

Query: 535  YELLHTLNFDAVRRRMSVIVKTQEGDILLFCKGADSAVFPRVQNHE--IELTKVHVERNA 592
            + +L+ L F + R+RMSVIV+T  G + L+CKGAD+ +F R+      +E T  H+E  A
Sbjct: 561  FGILNVLEFSSDRKRMSVIVRTPSGRLRLYCKGADNVIFERLSKDSKYMEETLCHLEYFA 620

Query: 593  MDGYRTLCVAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVE 652
             +G RTLCVA+ +++ ++YE   +   EA   L+DR +++E+ ++ IE N+ L+GATA+E
Sbjct: 621  TEGLRTLCVAYADLSENEYEEWLKVYQEASTILKDRAQRLEECYEIIEKNLLLLGATAIE 680

Query: 653  DKLQDQAAETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESE 712
            D+LQ    ETI  L  A +K+WVLTGDK ETA +  Y+CRL   N  L+ L         
Sbjct: 681  DRLQAGVPETIATLLKAEIKIWVLTGDKQETAINIGYSCRLVSQNMALILL--------- 731

Query: 713  RKEDRLHELLIEYRKKLLHEFPKSTRSFKKAWTEHQEYGLIIDGSTLSLILNSSQDSSSN 772
             KED L                +          +  +  LIIDG TL   L       S 
Sbjct: 732  -KEDSLDATRA--------AITQHCTDLGNLLGKENDVALIIDGHTLKYAL-------SF 775

Query: 773  NYKSIFLQICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMILESHV 832
              +  FL + + C AV+CCR++PLQK++IV +VK  +   ITL+IGDGANDV MI  +HV
Sbjct: 776  EVRRSFLDLALSCKAVICCRVSPLQKSEIVDVVKK-RVKAITLAIGDGANDVGMIQTAHV 834

Query: 833  GIGIKGKEGRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFILPQF 892
            G+GI G EG QA  NSDY++ +F +L+KLLL HG   Y R+   + Y FYKN+   + + 
Sbjct: 835  GVGISGNEGMQATNNSDYAIAQFSYLEKLLLVHGAWSYNRVTKCILYCFYKNVVLYIIEL 894

Query: 893  LYQFFCGFSQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPRLYMKISGNA 952
             + F  GFS Q L++   + +YN+ FT+LP     + E+    +++   P+LY       
Sbjct: 895  WFAFVNGFSGQILFERWCIGLYNVIFTALPPFTLGIFERSCTQESMLRFPQLYKITQNGE 954

Query: 953  MLQLGPFLYWTFLAAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFGTIVFTVLVFTVTL 1012
                  F      A     + F+      +  ++  +G        G IV+T +V TV L
Sbjct: 955  GFNTKVFWGHCINALVHSLILFWFPMKALEHDTVLTSGHATDYLFVGNIVYTYVVVTVCL 1014

Query: 1013 KLALDTRFWTWINHFVIWGS-LAFYVFFSFFWGGIIWPFLK-QQRMYFVFAQMLSSVSTW 1070
            K  L+T  WT  +H  +WGS L + VFF  +    IWP +     M      +LSS   W
Sbjct: 1015 KAGLETTAWTKFSHLAVWGSMLTWLVFFGIY--STIWPTIPIAPDMRGQATMVLSSAHFW 1072

Query: 1071 LAIILLIFISLFPEILLIVLKNVRRRS 1097
            L + L+    L  ++     K+  +++
Sbjct: 1073 LGLFLVPTACLIEDVAWRAAKHTCKKT 1099


>gi|5031697 ATPase, class I, type 8B, member 1 [Homo sapiens]
          Length = 1251

 Score =  595 bits (1533), Expect = e-169
 Identities = 370/1110 (33%), Positives = 594/1110 (53%), Gaps = 101/1110 (9%)

Query: 42   RFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLVQVTVDTPTSP-VTSGLPLFF 100
            ++ +N I + KY  + F+P NLFEQF+R AN YFL + ++Q      T    T+ +PL  
Sbjct: 91   KYANNAIKTYKYNAFTFIPMNLFEQFKRAANLYFLALLILQAVPQISTLAWYTTLVPLLV 150

Query: 101  VITVTAIKQGYEDWLRHRADNEVNKSTVYIIENAKRVRKESEKIKVGDVVEVQADETFPC 160
            V+ VTAIK   +D  RH+ D E+N  T  +I++ +    + ++I+VGDV+ ++ ++  P 
Sbjct: 151  VLGVTAIKDLVDDVARHKMDKEINNRTCEVIKDGRFKVAKWKEIQVGDVIRLKKNDFVPA 210

Query: 161  DLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIALCTAE-SIDTLRAAIECEQPQP 219
            D++LLSS   +  CYV TA LDGE+N K   ++  T      E ++ T    IECE+P  
Sbjct: 211  DILLLSSSEPNSLCYVETAELDGETNLKFKMSLEITDQYLQREDTLATFDGFIECEEPNN 270

Query: 220  DLYKFVGRINIYSNSLEAVARSLGPENLLLKGATLKNTEKIYGVAVYTGMETKMALNYQG 279
             L KF G +   + S       L  + +LL+G  ++NT+  +G+ ++ G +TK+  N   
Sbjct: 271  RLDKFTGTLFWRNTSFP-----LDADKILLRGCVIRNTDFCHGLVIFAGADTKIMKNSGK 325

Query: 280  KSQKRSAVEKSINAFLIVYLFILLTKAAVCTTLKYVWQSTPYNDEPWYNQKTQKERETLK 339
               KR+ ++  +N +++  +F++L   +    + + +      +  WY    + +  + +
Sbjct: 326  TRFKRTKIDYLMN-YMVYTIFVVLILLSAGLAIGHAYWEAQVGNSSWYLYDGEDDTPSYR 384

Query: 340  VLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFISWDKDFYDEEINEGALVNTSDL 399
                F  F  ++++ N ++P+S+YV+VE+ +   S FI+WD   Y  E +  A   T+ L
Sbjct: 385  G---FLIFWGYIIVLNTMVPISLYVSVEVIRLGQSHFINWDLQMYYAEKDTPAKARTTTL 441

Query: 400  NEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKY----------KGVTQEVDGLSQT-- 447
            NE+LGQ+ Y+F+DKTGTLT+N M F +CCI+G  Y              ++VD    T  
Sbjct: 442  NEQLGQIHYIFSDKTGTLTQNIMTFKKCCINGQIYGDHRDASQHNHNKIEQVDFSWNTYA 501

Query: 448  DGTLTYFD-----KVDKNRE---ELFLRALCLCHTVEIKTNDAVDGATESAELTYISSSP 499
            DG L ++D     ++   +E     F   L +CHTV +   D  DG     +L Y ++SP
Sbjct: 502  DGKLAFYDHYLIEQIQSGKEPEVRQFFFLLAVCHTVMV---DRTDG-----QLNYQAASP 553

Query: 500  DEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRRRMSVIVKTQEG 559
            DE ALV  A+ +GF FL      + +     E   Y +L  L+F++ R+RMS+IV+T EG
Sbjct: 554  DEGALVNAARNFGFAFLARTQNTITISELGTE-RTYNVLAILDFNSDRKRMSIIVRTPEG 612

Query: 560  DILLFCKGADSAVFPRVQNHEIELTKVHVERNAMDGY-----RTLCVAFKEIAPDDYERI 614
            +I L+CKGAD+ ++ R+  H +  TK   + +A+D +     RTLC+ +KEI   ++   
Sbjct: 613  NIKLYCKGADTVIYERL--HRMNPTKQETQ-DALDIFANETLRTLCLCYKEIEEKEFTEW 669

Query: 615  NRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAAETIEALHAAGLKVW 674
            N++ + A +A  +R+E ++KV+++IE ++ L+GATA+EDKLQD   ETI  L  A +K+W
Sbjct: 670  NKKFMAASVASTNRDEALDKVYEEIEKDLILLGATAIEDKLQDGVPETISKLAKADIKIW 729

Query: 675  VLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERKEDRLHELLIEYRKK--LLHE 732
            VLTGDK ETA++  +AC L   +T        TI   E     LH  +   R +  +  +
Sbjct: 730  VLTGDKKETAENIGFACELLTEDT--------TICYGEDINSLLHARMENQRNRGGVYAK 781

Query: 733  F-PKSTRSFKKAWTEHQEYGLIIDGSTLSLILNSSQ------------------------ 767
            F P    SF   +       LII GS L+ IL   +                        
Sbjct: 782  FAPPVQESF---FPPGGNRALIITGSWLNEILLEKKTKRNKILKLKFPRTEEERRMRTQS 838

Query: 768  ----DSSSNNYKSIFLQICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGAND 823
                ++     +  F+ +  +C+AV+CCR+ P QKA +V +VK  K   ITL+IGDGAND
Sbjct: 839  KRRLEAKKEQRQKNFVDLACECSAVICCRVTPKQKAMVVDLVKRYK-KAITLAIGDGAND 897

Query: 824  VSMILESHVGIGIKGKEGRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYK 883
            V+MI  +H+G+GI G+EG QA  +SDYS  +F++L++LLL HG   Y+R+   ++YFFYK
Sbjct: 898  VNMIKTAHIGVGISGQEGMQAVMSSDYSFAQFRYLQRLLLVHGRWSYIRMCKFLRYFFYK 957

Query: 884  NLCFILPQFLYQFFCGFSQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPR 943
            N  F L  F Y FF G+S Q  Y+  ++T+YN+ +TSLP+L   LL+Q ++       P 
Sbjct: 958  NFAFTLVHFWYSFFNGYSAQTAYEDWFITLYNVLYTSLPVLLMGLLDQDVSDKLSLRFPG 1017

Query: 944  LYMKISGNAMLQLGPFLYWTFLAAFEGTVFFF---GTYFLFQTASLEENGKVYGNW-TFG 999
            LY+    + +     F            + FF   G Y      ++ ++G+   ++ +F 
Sbjct: 1018 LYIVGQRDLLFNYKRFFVSLLHGVLTSMILFFIPLGAYL----QTVGQDGEAPSDYQSFA 1073

Query: 1000 TIVFTVLVFTVTLKLALDTRFWTWINHFVIWGSLAFY--VFFSFFWGGIIWPFLKQQRMY 1057
              + + LV TV  ++ LDT +WT++N F I+GS+A Y  + F F   GI   F    +  
Sbjct: 1074 VTIASALVITVNFQIGLDTSYWTFVNAFSIFGSIALYFGIMFDFHSAGIHVLFPSAFQFT 1133

Query: 1058 FVFAQMLSSVSTWLAIILLIFISLFPEILL 1087
               +  L     WL IIL + + L P + +
Sbjct: 1134 GTASNALRQPYIWLTIILTVAVCLLPVVAI 1163


>gi|44888835 ATPase, class I, type 8B, member 3 [Homo sapiens]
          Length = 1300

 Score =  517 bits (1332), Expect = e-146
 Identities = 346/1120 (30%), Positives = 568/1120 (50%), Gaps = 110/1120 (9%)

Query: 41   QRFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLVQVTVDTPTSPVTS-GLPLF 99
            +++  N I ++KY  ++FLP NL+EQF R++N +FLII ++Q   D  T P  S   P+ 
Sbjct: 131  KKYKTNVIRTAKYNFYSFLPLNLYEQFHRVSNLFFLIIIILQSIPDISTLPWFSLSTPMV 190

Query: 100  FVITVTAIKQGYEDWLRHRADNEVNKSTVYIIENAKRVRKESEKIKVGDVVEVQADETFP 159
             ++ + A +   +D  RH++D  +N     I+      +K+ + + VGDVV ++ D   P
Sbjct: 191  CLLFIRATRDLVDDMGRHKSDRAINNRPCQILMGKSFKQKKWQDLCVGDVVCLRKDNIVP 250

Query: 160  CDLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIA-LCTAESIDTLRAAIECEQPQ 218
             D++LL+S      CYV T  +DGE+N K   A+  T   L T + + + +  + CE P 
Sbjct: 251  ADMLLLASTEPSSLCYVETVDIDGETNLKFRQALMVTHKELATIKKMASFQGTVTCEAPN 310

Query: 219  PDLYKFVGRINIYSNSLEAVARSLGPENLLLKGATLKNTEKIYGVAVYTGMETKMALNYQ 278
              ++ FVG +            SL   NLLL+G  ++NT+  YG+ +Y G +TK+  N  
Sbjct: 311  SRMHHFVGCLEWNDKKY-----SLDIGNLLLRGCRIRNTDTCYGLVIYAGFDTKIMKNCG 365

Query: 279  GKSQKRSAVEKSINAFLIVYLFILLTKAAVCTTLKYVWQSTPYNDEPWYNQKTQKERETL 338
                KR+ ++  +N  L+V +FI +    +     + +    + D  +Y           
Sbjct: 366  KIHLKRTKLDLLMNK-LVVVIFISVVLVCLVLAFGFGFSVKEFKDHHYYLSGVHGSSVAA 424

Query: 339  KVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFISWDKDFYDEEINEGALVNTSD 398
            +    F  F SF++L +  IP+SM++  E      S FI WD   Y +  +  A   ++ 
Sbjct: 425  E---SFFVFWSFLILLSVTIPMSMFILSEFIYLGNSVFIDWDVQMYYKPQDVPAKARSTS 481

Query: 399  LNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKYKGVTQEVDGLSQT--------DGT 450
            LN+ LGQV+Y+F+DKTGTLT+N + F +CCI G  Y   ++      +         DG 
Sbjct: 482  LNDHLGQVEYIFSDKTGTLTQNILTFNKCCISGRVYGPDSEATTRPKENPYLWNKFADGK 541

Query: 451  LTYFDK-----VDKNREEL---FLRALCLCHTVEIKTNDAVDGATESAELTYISSSPDEI 502
            L + +      V  N +E    F R L +CHTV ++ +          +L Y ++SPDE 
Sbjct: 542  LLFHNAALLHLVRTNGDEAVREFWRLLAICHTVMVRESPR----ERPDQLLYQAASPDEG 597

Query: 503  ALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRRRMSVIVKTQEGDIL 562
            ALV  A+ +G+ FL      + +    +E   Y++L  ++F++ R+RMSV+V+  EG I 
Sbjct: 598  ALVTAARNFGYVFLSRTQDTVTIMELGEE-RVYQVLAIMDFNSTRKRMSVLVRKPEGAIC 656

Query: 563  LFCKGADSAVFPRVQNHEIE--LTKVHVERNAMDGYRTLCVAFKEIAPDDYERINRQLIE 620
            L+ KGAD+ +F R+         T+  +   A +  RTLC+A++E+A D YE   ++  E
Sbjct: 657  LYTKGADTVIFERLHRRGAMEFATEEALAAFAQETLRTLCLAYREVAEDIYEDWQQRHQE 716

Query: 621  AKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAAETIEALHAAGLKVWVLTGDK 680
            A + LQ+R + +++          L+GATA+ED+LQD   ETI+ L  + +K+WVLTGDK
Sbjct: 717  ASLLLQNRAQALQQ----------LLGATAIEDRLQDGVPETIKCLKKSNIKIWVLTGDK 766

Query: 681  METAKSTCYACRLFQTNTELLE------------------LTTKTIEESER----KEDRL 718
             ETA +  +AC L   N  +LE                  LT +++ + +       D L
Sbjct: 767  QETAVNIGFACELLSENMLILEEKEISRILETYWENSNNLLTRESLSQVKLALVINGDFL 826

Query: 719  HELLIEYRKK------------LLHEFPKSTRSFKKAWTEHQEYGLIIDGSTLSLILNSS 766
             +LL+  RK+               E  +S R F  A    +   L+     L L    +
Sbjct: 827  DKLLVSLRKEPRALAQNVNMDEAWQELGQSRRDFLYA----RRLSLLCRRFGLPLAAPPA 882

Query: 767  QDSSSNNYKSI-----FLQICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGA 821
            QDS +     +     F+ +  KC AV+CCR+ P QKA IV +VK      +TL+IGDGA
Sbjct: 883  QDSRARRSSEVLQERAFVDLASKCQAVICCRVTPKQKALIVALVKKYH-QVVTLAIGDGA 941

Query: 822  NDVSMILESHVGIGIKGKEGRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFF 881
            ND++MI  + VG+G+ G+EG QA +NSD+ + +F  L++LLL HG   YVRI   ++YFF
Sbjct: 942  NDINMIKTADVGVGLAGQEGMQAVQNSDFVLGQFCFLQRLLLVHGRWSYVRICKFLRYFF 1001

Query: 882  YKNLCFILPQFLYQFFCGFSQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSD 941
            YK++  ++ Q  +  + GF+ QPLY+  +L ++N+ +++LP+L   L EQ ++ +     
Sbjct: 1002 YKSMASMMVQVWFACYNGFTGQPLYEGWFLALFNLLYSTLPVLYIGLFEQDVSAEQSLEK 1061

Query: 942  PRLYMKISGNAMLQLGPFLYWTFLAAF-EGTVFFFGTYFLFQTASLEENG--KVYGNWTF 998
            P LY+    + +     F YW F+ A   G       +F+    S +  G      + +F
Sbjct: 1062 PELYVVGQKDEL-----FNYWVFVQAIAHGVTTSLVNFFMTLWISRDTAGPASFSDHQSF 1116

Query: 999  GTIVFTVLVFTVTLKLALDTRFWTWINHFVIWGSLAFYV--------FFSFFWGGIIWPF 1050
              +V    + ++T+++ L  ++WT +    I  SL FY         F+ F      +PF
Sbjct: 1117 AVVVALSCLLSITMEVILIIKYWTALCVATILLSLGFYAIMTTTTQSFWLFRVSPTTFPF 1176

Query: 1051 LKQQRMYFVFAQMLSSVSTWLAIILLIFISLFPEILLIVL 1090
            L      +    ++SS S  L ++L + I+ FP + L V+
Sbjct: 1177 L------YADLSVMSSPSILLVVLLSVSINTFPVLALRVI 1210


>gi|65301139 ATPase, class II, type 9A [Homo sapiens]
          Length = 1047

 Score =  445 bits (1144), Expect = e-124
 Identities = 327/1108 (29%), Positives = 528/1108 (47%), Gaps = 126/1108 (11%)

Query: 13   CAGEEKRVGTRTVFVGNHPVSETEAYIAQRFCDNRIVSSKYTLWNFLPKNLFEQFRRIAN 72
            C G E R   RTV++G HP         QR+  N I + KY  + FLP  LF QF+   N
Sbjct: 31   CGGGEAR--PRTVWLG-HPEKRD-----QRYPRNVINNQKYNFFTFLPGVLFNQFKYFFN 82

Query: 73   FYFLIIFLVQVTVDTPTSPV-TSGLPLFFVITVTAIKQGYEDWLRHRADNEVNKSTVYII 131
             YFL++   Q   +     + T  +PL FV+ VT I++  E+   +  D EVN      +
Sbjct: 83   LYFLLLACSQFVPEMRLGALYTYWVPLGFVLAVTVIREAVEEIRCYVRDKEVNSQVYSRL 142

Query: 132  ENAKRVRKESEKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHY 191
                 V+ +S  I+VGD++ V+ ++  P D+I L +   +G+C++ T  LDGE++ K   
Sbjct: 143  TARGTVKVKSSNIQVGDLIIVEKNQRVPADMIFLRTSEKNGSCFLRTDQLDGETDWKLRL 202

Query: 192  AVRDTIALCTAESIDTLRAAIECEQPQPDLYKFVGRINIYSNSLEAVARSLGPENLLLKG 251
             V  T  L TA  +  +R+ +  E+P  D++ FVG      +S   ++ SL  EN L  G
Sbjct: 203  PVACTQRLPTAADLLQIRSYVYAEEPNIDIHNFVGTFT-REDSDPPISESLSIENTLWAG 261

Query: 252  ATLKNTEKIYGVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLFILLTKAAVCTT 311
             T+  +  + GV +YTG E +  +N      K    +  +N    +    L+  + V   
Sbjct: 262  -TVVASGTVVGVVLYTGRELRSVMNTSNPRSKIGLFDLEVNCLTKILFGALVVVSLVMVA 320

Query: 312  LKYVWQSTPYNDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKF 371
            L++           WY Q                  + F++LF+ IIP+S+ V ++M K 
Sbjct: 321  LQHFAGR-------WYLQ-----------------IIRFLLLFSNIIPISLRVNLDMGKI 356

Query: 372  LGSFFISWDKDFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECC--- 428
            + S+ I  D          G +V +S + E+LG++ Y+ TDKTGTLT+N M F       
Sbjct: 357  VYSWVIRRDSKI------PGTVVRSSTIPEQLGRISYLLTDKTGTLTQNEMIFKRLHLGT 410

Query: 429  ----------IDGHKYKGVTQEV-DGLSQTDGTLTY-FDKVDKNREELFLRALCLCHTVE 476
                      +  H +   TQ+  D  +Q   TLT    +   +R    ++A+ LCH V 
Sbjct: 411  VAYGLDSMDEVQSHIFSIYTQQSQDPPAQKGPTLTTKVRRTMSSRVHEAVKAIALCHNVT 470

Query: 477  --IKTNDAVDGAT-----ESAELTYISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQR 529
               ++N   D A      E +   Y +SSPDE+ALV+  +  G T +G     M++    
Sbjct: 471  PVYESNGVTDQAEAEKQYEDSCRVYQASSPDEVALVQWTESVGLTLVGRDQSSMQLRTPG 530

Query: 530  KEIEEYELLHTLNFDAVRRRMSVIVKTQE-GDILLFCKGADSAVFPRVQNHEIELTKVHV 588
             +I  + +L    F    +RM +IV+ +  G+I  + KGAD  +   VQ ++    +   
Sbjct: 531  DQILNFTILQIFPFTYESKRMGIIVRDESTGEITFYMKGADVVMAGIVQYND--WLEEEC 588

Query: 589  ERNAMDGYRTLCVAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGA 648
               A +G R L VA K +A + Y+    + ++AK+++ DR  K+  V + +E  M L+  
Sbjct: 589  GNMAREGLRVLVVAKKSLAEEQYQDFEARYVQAKLSVHDRSLKVATVIESLEMEMELLCL 648

Query: 649  TAVEDKLQDQAAETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTI 708
            T VED+LQ     T+E L  AG+KVW+LTGDK+ETA  T     L   N ++      T 
Sbjct: 649  TGVEDQLQADVRPTLETLRNAGIKVWMLTGDKLETATCTAKNAHLVTRNQDIHVFRLVT- 707

Query: 709  EESERKEDRLHELLIEYRKKLLHEFPKSTRSFKKAWTEHQEYGLIIDGSTLSLILNSSQD 768
                      H  L  +R+K                    +  L+I G +L + L     
Sbjct: 708  -----NRGEAHLELNAFRRK-------------------HDCALVISGDSLEVCLKY--- 740

Query: 769  SSSNNYKSIFLQICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMIL 828
                 Y+  F+++  +C AV+CCR AP QKAQIVR+++   G  +T ++GDG NDVSMI 
Sbjct: 741  -----YEYEFMELACQCPAVVCCRCAPTQKAQIVRLLQERTGK-LTCAVGDGGNDVSMIQ 794

Query: 829  ESHVGIGIKGKEGRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFI 888
            ES  G+G++GKEG+QA+  +D+S+ +FKHL +LL+ HG   Y R A L Q+  +++LC  
Sbjct: 795  ESDCGVGVEGKEGKQASLAADFSITQFKHLGRLLMVHGRNSYKRSAALSQFVIHRSLCIS 854

Query: 889  LPQFLYQFFCGFSQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPRLYMKI 948
              Q ++     F+  PLY    +  Y+  +T  P+ +  +L++ +  +     P LY  +
Sbjct: 855  TMQAVFSSVFYFASVPLYQGFLIIGYSTIYTMFPVFSL-VLDKDVKSEVAMLYPELYKDL 913

Query: 949  SGNAMLQLGPFLYWTFLAAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFGTIVFTVLVF 1008
                 L    FL W  ++ ++G+   +G   LF++  +              I FT L+ 
Sbjct: 914  LKGRPLSYKTFLIWVLISIYQGSTIMYGALLLFESEFVH----------IVAISFTSLIL 963

Query: 1009 TVTLKLALDTRFWTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQQRMYFVFAQMLSSVS 1068
            T  L +AL  + W W+       SLA Y+        ++  FL +    F+    ++++S
Sbjct: 964  TELLMVALTIQTWHWLMTVAELLSLACYI------ASLV--FLHE----FIDVYFIATLS 1011

Query: 1069 TWLAIILLIFISLFPEILLIVLKNVRRR 1096
                + ++  +S  P   L VLK +RRR
Sbjct: 1012 FLWKVSVITLVSCLP---LYVLKYLRRR 1036


>gi|41327760 ATPase, class II, type 9B [Homo sapiens]
          Length = 1147

 Score =  412 bits (1059), Expect = e-115
 Identities = 314/1121 (28%), Positives = 526/1121 (46%), Gaps = 135/1121 (12%)

Query: 17   EKRVGTRTVFVGNHPVSETEAYIAQRFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFL 76
            +K +  RTV++G     E      ++   N I + KY ++ F+P  L+EQF+   N YFL
Sbjct: 110  KKELKARTVWLGCPEKCE------EKHPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFL 163

Query: 77   IIFLVQVTVDTPTSPV-TSGLPLFFVITVTAIKQGYEDWLRHRADNEVNKSTVYIIENAK 135
            +I   Q         + T   PL FV+ VT  ++  +++ R + D EVN      +    
Sbjct: 164  VISCSQFVPALKIGYLYTYWAPLGFVLAVTMTREAIDEFRRFQRDKEVNSQLYSKLTVRG 223

Query: 136  RVRKESEKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRD 195
            +V+ +S  I+VGD++ V+ ++  P D++ L +    G+C++ T  LDGE++ K   AV  
Sbjct: 224  KVQVKSSDIQVGDLIIVEKNQRIPSDMVFLRTSEKAGSCFIRTDQLDGETDWKLKVAVSC 283

Query: 196  TIALCTAESIDTLRAAIECEQPQPDLYKFVGRINIYSNSLEAVARSLGPENLLLKGATLK 255
            T  L     + ++ A +  ++PQ D++ F G      +S   +  SL  EN L   +T+ 
Sbjct: 284  TQQLPALGDLFSISAYVYAQKPQMDIHSFEGTFT-REDSDPPIHESLSIENTLW-ASTIV 341

Query: 256  NTEKIYGVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLFILLTKAAVCTTLK-Y 314
             +  + GV +YTG ET+  +N      K   ++  +N         L+  + V  TL+ +
Sbjct: 342  ASGTVIGVVIYTGKETRSVMNTSNPKNKVGLLDLELNRLTKALFLALVALSIVMVTLQGF 401

Query: 315  VWQSTPYNDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGS 374
            V         PWY                  +   F++LF++IIP+S+ V ++M K +  
Sbjct: 402  VG--------PWYR-----------------NLFRFLLLFSYIIPISLRVNLDMGKAVYG 436

Query: 375  FFISWDKDFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKY 434
            + +  D++        G +V TS + EELG++ Y+ TDKTGTLT+N M F    +    Y
Sbjct: 437  WMMMKDENI------PGTVVRTSTIPEELGRLVYLLTDKTGTLTQNEMIFKRLHLGTVSY 490

Query: 435  KGVTQEV----------DGLSQTDGTLTYFDKVDK-------------NREELFLRALCL 471
               T +              SQ  G  T    + K             +R    ++A+ L
Sbjct: 491  GADTMDEIQSHVRDSYSQMQSQAGGNNTGSTPLRKAQSSAPKVRKSVSSRIHEAVKAIVL 550

Query: 472  CHTVE--IKTNDAVDGATESAEL---------TYISSSPDEIALVKGAKRYGFTFLGNRN 520
            CH V    ++   V   TE AE          TY +SSPDE+ALV+  +  G T +    
Sbjct: 551  CHNVTPVYESRAGVTEETEFAEADQDFSDENRTYQASSPDEVALVQWTESVGLTLVSRDL 610

Query: 521  GYMRVENQRKEIEEYELLHTLNFDAVRRRMSVIVKTQE-GDILLFCKGADSAVFPRVQNH 579
              M+++    ++  + +L    F +  +RM VIV+ +   +I  + KGAD A+ P VQ +
Sbjct: 611  TSMQLKTPSGQVLSFCILQLFPFTSESKRMGVIVRDESTAEITFYMKGADVAMSPIVQYN 670

Query: 580  EIELTKVHVERNAMDGYRTLCVAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDI 639
            +    +      A +G RTL VA K +  + Y+    +  +AK+++ DR  K+  V + +
Sbjct: 671  D--WLEEECGNMAREGLRTLVVAKKALTEEQYQDFESRYTQAKLSMHDRSLKVAAVVESL 728

Query: 640  ETNMNLIGATAVEDKLQDQAAETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTE 699
            E  M L+  T VED+LQ     T+E L  AG+K+W+LTGDK+ETA     +  L  + T+
Sbjct: 729  EREMELLCLTGVEDQLQADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSSHLV-SRTQ 787

Query: 700  LLELTTKTIEESERKEDRLHELLIEYRKKLLHEFPKSTRSFKKAWTEHQEYGLIIDGSTL 759
             + +  +     E      H  L  +R+K                    +  L+I G +L
Sbjct: 788  DIHIFRQVTSRGEA-----HLELNAFRRK-------------------HDCALVISGDSL 823

Query: 760  SLILNSSQDSSSNNYKSIFLQICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGD 819
             + L          Y+  F+++  +C AV+CCR +P QKA+IV +++   G   T +IGD
Sbjct: 824  EVCLKY--------YEHEFVELACQCPAVVCCRCSPTQKARIVTLLQQHTGRR-TCAIGD 874

Query: 820  GANDVSMILESHVGIGIKGKEGRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQY 879
            G NDVSMI  +  GIGI+GKEG+QA+  +D+S+ +F+H+ +LL+ HG   Y R A L Q+
Sbjct: 875  GGNDVSMIQAADCGIGIEGKEGKQASLAADFSITQFRHIGRLLMVHGRNSYKRSAALGQF 934

Query: 880  FFYKNLCFILPQFLYQFFCGFSQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLT 939
              ++ L     Q ++     F+  PLY    +  Y   +T  P+ +  +L+Q +  +   
Sbjct: 935  VMHRGLIISTMQAVFSSVFYFASVPLYQGFLMVGYATIYTMFPVFSL-VLDQDVKPEMAM 993

Query: 940  SDPRLYMKISGNAMLQLGPFLYWTFLAAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFG 999
              P LY  ++    L    FL W  ++ ++G +  +G   LF++  +             
Sbjct: 994  LYPELYKDLTKGRSLSFKTFLIWVLISIYQGGILMYGALVLFESEFVH----------VV 1043

Query: 1000 TIVFTVLVFTVTLKLALDTRFWTWINHFVIWGSLAFYV----FFSFFWGGIIWPFLKQQR 1055
             I FT L+ T  L +AL  R W W+     + SL  YV    F + ++G       +   
Sbjct: 1044 AISFTALILTELLMVALTVRTWHWLMVVAEFLSLGCYVSSLAFLNEYFG-----IGRVSF 1098

Query: 1056 MYFVFAQMLSSVSTWLAIILLIFISLFPEILLIVLKNVRRR 1096
              F+    +++V+    +  +  +S  P   L VLK +RR+
Sbjct: 1099 GAFLDVAFITTVTFLWKVSAITVVSCLP---LYVLKYLRRK 1136


>gi|149944474 ATPase, class V, type 10B [Homo sapiens]
          Length = 1461

 Score =  361 bits (926), Expect = 2e-99
 Identities = 218/629 (34%), Positives = 333/629 (52%), Gaps = 38/629 (6%)

Query: 491  ELTYISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRRRM 550
            E  Y + SPDE ALV  A  Y FT +      + V   +     + LL TL FD+VR+RM
Sbjct: 714  EFCYEAESPDEAALVHAAHAYSFTLVSRTPEQVTVRLPQGTCLTFSLLCTLGFDSVRKRM 773

Query: 551  SVIVKTQ-EGDILLFCKGADSAVFPRVQ--------NHEIELTKV------HVERNAMDG 595
            SV+V+    G+I+++ KGADS +   ++        N E +L K+      H++  A DG
Sbjct: 774  SVVVRHPLTGEIVVYTKGADSVIMDLLEDPACVPDINMEKKLRKIRARTQKHLDLYARDG 833

Query: 596  YRTLCVAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKL 655
             RTLC+A K ++ +D+ R      EA+ +L +R+E + +    +E  + L+GAT +ED+L
Sbjct: 834  LRTLCIAKKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQLTLLGATGIEDRL 893

Query: 656  QDQAAETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESE--- 712
            Q+   +TI  L  AG+++WVLTGDK ETA +  ++CRL      +  + T+  E  E   
Sbjct: 894  QEGVPDTIATLREAGIQLWVLTGDKQETAVNIAHSCRLLNQTDTVYTINTENQETCESIL 953

Query: 713  ----RKEDRLHELLIEYRKKLLHEFPKSTRSFKKAWTEHQEYGLIIDGSTLSLILNSSQD 768
                 +  +  EL    RK      P  T S         E GL+IDG TL+ I     +
Sbjct: 954  NCALEELKQFRELQKPDRKLFGFRLPSKTPSITSEAVV-PEAGLVIDGKTLNAIFQGKLE 1012

Query: 769  SSSNNYKSIFLQICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMIL 828
                     FL++   C +VLCCR  PLQK+ IV++V++ K   +TLSIGDGANDVSMI 
Sbjct: 1013 KK-------FLELTQYCRSVLCCRSTPLQKSMIVKLVRD-KLRVMTLSIGDGANDVSMIQ 1064

Query: 829  ESHVGIGIKGKEGRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFI 888
             + +GIGI G+EG QA  +SD+++ +FKHLKKLLL HGH  Y R+A +V Y+ YKN+C++
Sbjct: 1065 AADIGIGISGQEGMQAVMSSDFAITRFKHLKKLLLVHGHWCYSRLARMVVYYLYKNVCYV 1124

Query: 889  LPQFLYQFFCGFSQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPRLYMKI 948
               F YQFFCGFS   + D   +  +N+ FTSLP L + +L++ I+ +TL + P LY   
Sbjct: 1125 NLLFWYQFFCGFSSSTMIDYWQMIFFNLFFTSLPPLVFGVLDKDISAETLLALPELYKSG 1184

Query: 949  SGNAMLQLGPFLYWTFLAAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFGTIVFTVLVF 1008
              +    L  F      A ++  + FF  Y  ++ + ++        +TFGT + T+ + 
Sbjct: 1185 QNSECYNLSTFWISMVDAFYQSLICFFIPYLAYKGSDIDV-------FTFGTPINTISLT 1237

Query: 1009 TVTLKLALDTRFWTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQQRMYFVFAQMLSSVS 1068
            T+ L  A++ + WT  +  V+ GS   Y   S  +             Y+V    LS+ +
Sbjct: 1238 TILLHQAMEMKTWTIFHGVVLLGSFLMYFLVSLLYNATCVICNSPTNPYWVMEGQLSNPT 1297

Query: 1069 TWLAIILLIFISLFPEILLIVLKNVRRRS 1097
             +L   L   ++L P    + L+    +S
Sbjct: 1298 FYLVCFLTPVVALLPRYFFLSLQGTCGKS 1326



 Score =  253 bits (646), Expect = 7e-67
 Identities = 148/416 (35%), Positives = 225/416 (54%), Gaps = 10/416 (2%)

Query: 23  RTVFVGNHPVSETEAYIAQRFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLVQ 82
           R VF  N    +    +++R+  NR  ++KYTL+ FLP+NLFEQF R AN YFL + ++ 
Sbjct: 46  RVVFPNNSIFHQDWEEVSRRYPGNRTCTTKYTLFTFLPRNLFEQFHRWANLYFLFLVILN 105

Query: 83  --VTVDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHRADNEVNKSTVYIIENAKR--VR 138
              +++     +T  LPL  V+ V  IK G ED+ RHR D  +N S + I E  ++  V+
Sbjct: 106 WMPSMEVFHREITM-LPLAIVLFVIMIKDGMEDFKRHRFDKAINCSNIRIYERKEQTYVQ 164

Query: 139 KESEKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIA 198
           K  + ++VGD ++++ +E  P D++LL S   +G C++ TASLDGE+N K    V+    
Sbjct: 165 KCWKDVRVGDFIQMKCNEIVPADILLLFSSDPNGICHLETASLDGETNLKQRCVVKGFSQ 224

Query: 199 LCTAESIDTLRAAIECEQPQPDLYKFVGRINIYSNSLEAVARSLGPENLLLKGATLKNTE 258
                  +     I CE+P   L KF G    Y    +      G E+LLL+G T++NTE
Sbjct: 225 QEVQFEPELFHNTIVCEKPNNHLNKFKG----YMEHPDQTRTGFGCESLLLRGCTIRNTE 280

Query: 259 KIYGVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLFILLTKAAVCTTLKYVWQS 318
              G+ +Y G ETK  LN  G   KRS +E+ +N  +   + IL+    +      +W  
Sbjct: 281 MAVGIVIYAGHETKAMLNNSGPRYKRSKIERRMNIDIFFCIGILILMCLIGAVGHSIWNG 340

Query: 319 TPYNDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFIS 378
           T + + P ++            L  F  FL+ ++L   +IP+S+YV++E+ K    FF+S
Sbjct: 341 T-FEEHPPFDVPDANGSFLPSALGGFYMFLTMIILLQVLIPISLYVSIELVKLGQVFFLS 399

Query: 379 WDKDFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKY 434
            D D YDEE +        ++ E+LGQ+ Y+F+DKTGTLTEN M F  C I G +Y
Sbjct: 400 NDLDLYDEETDLSIQCRALNIAEDLGQIQYIFSDKTGTLTENKMVFRRCTIMGSEY 455


>gi|222352161 ATPase, class V, type 10D [Homo sapiens]
          Length = 1426

 Score =  348 bits (893), Expect = 2e-95
 Identities = 219/638 (34%), Positives = 336/638 (52%), Gaps = 53/638 (8%)

Query: 481  DAVDGATESAELTYISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHT 540
            +++ G   +  L Y + SPDE ALV  A+ Y  T        + V+        ++LLH 
Sbjct: 710  ESLPGQPLACNLCYEAESPDEAALVYAARAYQCTLRSRTPEQVMVDFAALGPLTFQLLHI 769

Query: 541  LNFDAVRRRMSVIVKTQ-EGDILLFCKGADSAVFP-------------RVQNHEIELTKV 586
            L FD+VR+RMSV+V+      ++++ KGADS +               + Q    E T+ 
Sbjct: 770  LPFDSVRKRMSVVVRHPLSNQVVVYTKGADSVIMELLSVASPDGASLEKQQMIVREKTQK 829

Query: 587  HVERNAMDGYRTLCVAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLI 646
            H++  A  G RTLC+A K ++  +Y    R    A+ ++ +REE + +    +E  + L+
Sbjct: 830  HLDDYAKQGLRTLCIAKKVMSDTEYAEWLRNHFLAETSIDNREELLLESAMRLENKLTLL 889

Query: 647  GATAVEDKLQDQAAETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTK 706
            GAT +ED+LQ+   E+IEALH AG+K+W+LTGDK ETA +  YAC+L + + +L  L T+
Sbjct: 890  GATGIEDRLQEGVPESIEALHKAGIKIWMLTGDKQETAVNIAYACKLLEPDDKLFILNTQ 949

Query: 707  T-----------IEESERKEDRLHELLIEYRKKLLHEFPKSTRSFKKAWTEHQEYGLIID 755
            +           ++E ++K   L E +      L    P+ +             GLII 
Sbjct: 950  SKDACGMLMSTILKELQKKTQALPEQVSLSEDLLQPPVPRDSGL---------RAGLIIT 1000

Query: 756  GSTLSLILNSSQDSSSNNYKSIFLQICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITL 815
            G TL   L  S           FL++   C AV+CCR  PLQK+++V++V++     +TL
Sbjct: 1001 GKTLEFALQESLQKQ-------FLELTSWCQAVVCCRATPLQKSEVVKLVRSHL-QVMTL 1052

Query: 816  SIGDGANDVSMILESHVGIGIKGKEGRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAH 875
            +IGDGANDVSMI  + +GIG+ G+EG QA   SD++V +FKHL KLLL HGH  Y R+++
Sbjct: 1053 AIGDGANDVSMIQVADIGIGVSGQEGMQAVMASDFAVSQFKHLSKLLLVHGHWCYTRLSN 1112

Query: 876  LVQYFFYKNLCFILPQFLYQFFCGFSQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINI 935
            ++ YFFYKN+ ++   F YQFFCGFS   + D   L  +N+ FTS P + Y +LE+ ++ 
Sbjct: 1113 MILYFFYKNVAYVNLLFWYQFFCGFSGTSMTDYWVLIFFNLLFTSAPPVIYGVLEKDVSA 1172

Query: 936  DTLTSDPRLYMKISGNAMLQLGPFLYWTFL--AAFEGTVFFFGTYFLFQTASLEENGKVY 993
            +TL   P LY   SG       P  +W  L  A ++  V FF  YF +Q       G   
Sbjct: 1173 ETLMQLPELYR--SGQKSEAYLPHTFWITLLDAFYQSLVCFFVPYFTYQ-------GSDT 1223

Query: 994  GNWTFGTIVFTVLVFTVTLKLALDTRFWTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQ 1053
              + FG  + T  +F V L L ++++  TWI+  VI GS+  Y  F+  +G +       
Sbjct: 1224 DIFAFGNPLNTAALFIVLLHLVIESKSLTWIHLLVIIGSILSYFLFAIVFGAMCVTCNPP 1283

Query: 1054 QRMYFVFAQMLSSVSTWLAIILLIFISLFPEILLIVLK 1091
               Y++  + +     +L  IL   I+L P  +  VL+
Sbjct: 1284 SNPYWIMQEHMLDPVFYLVCILTTSIALLPRFVYRVLQ 1321



 Score =  248 bits (632), Expect = 3e-65
 Identities = 147/431 (34%), Positives = 230/431 (53%), Gaps = 23/431 (5%)

Query: 43  FCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLVQVT--VDTPTSPVTSGLPLFF 100
           + +NRI ++KYTL NF+P+NLFEQF R AN YFL + ++     V+     +T  LPL  
Sbjct: 71  YVNNRIRTTKYTLLNFVPRNLFEQFHRAANLYFLFLVVLNWVPLVEAFQKEITM-LPLVV 129

Query: 101 VITVTAIKQGYEDWLRHRADNEVNK--STVYIIENAKRVRKESEKIKVGDVVEVQADETF 158
           V+T+ AIK G ED+ +++ D ++N   + VY  +  K + +  + + VGD + +  +E  
Sbjct: 130 VLTIIAIKDGLEDYRKYKIDKQINNLITKVYSRKEKKYIDRCWKDVTVGDFIRLSCNEVI 189

Query: 159 PCDLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIALCTAESIDTLRAAIECEQPQ 218
           P D++LL S   DG C++ T+ LDGESN K    VR      +    +   + IECE P 
Sbjct: 190 PADMVLLFSTDPDGICHIETSGLDGESNLKQRQVVRGYAEQDSEVDPEKFSSRIECESPN 249

Query: 219 PDLYKFVGRINIYSNSLEAVARSLGPENLLLKGATLKNTEKIYGVAVYTGMETKMALNYQ 278
            DL +F G +  +SN        L  ENLLL+G T++NTE + G+ VY G ETK  LN  
Sbjct: 250 NDLSRFRGFLE-HSNKERV---GLSKENLLLRGCTIRNTEAVVGIVVYAGHETKAMLNNS 305

Query: 279 GKSQKRSAVEKSINAFLIVYLFILLTKAAVCTTLKYVWQSTPYNDEPWYNQKTQKERETL 338
           G   KRS +E+  N  ++  + +L+           +W S  Y    ++N          
Sbjct: 306 GPRYKRSKLERRANTDVLWCVMLLVIMCLTGAVGHGIWLSR-YEKMHFFNVPEPDGHIIS 364

Query: 339 KVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFISWDKDFYDEEINEGALVNTSD 398
            +L  F  F + ++L   +IP+S+YV++E+ K    +FI  D DFY+E+++        +
Sbjct: 365 PLLAGFYMFWTMIILLQVLIPISLYVSIEIVKLGQIYFIQSDVDFYNEKMDSIVQCRALN 424

Query: 399 LNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKY-------------KGVTQEVDGLS 445
           + E+LGQ+ Y+F+DKTGTLTEN M F  C + G  Y             + V+++ D + 
Sbjct: 425 IAEDLGQIQYLFSDKTGTLTENKMVFRRCSVAGFDYCHEENARRLESYQEAVSEDEDFID 484

Query: 446 QTDGTLTYFDK 456
              G+L+   K
Sbjct: 485 TVSGSLSNMAK 495


>gi|14424433 ATPase, class V, type 10A [Homo sapiens]
          Length = 1499

 Score =  345 bits (885), Expect = 1e-94
 Identities = 211/621 (33%), Positives = 338/621 (54%), Gaps = 46/621 (7%)

Query: 491  ELTYISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRRRM 550
            EL Y + SPDE ALV  A+ Y    +   +  + VE        +ELLHTL FD+VR+RM
Sbjct: 690  ELRYEAESPDEAALVYAARAYNCVLVERLHDQVSVELPHLGRLTFELLHTLGFDSVRKRM 749

Query: 551  SVIVKTQEGD-ILLFCKGADSAVFPRVQ---------NHEIEL---TKVHVERNAMDGYR 597
            SV+++    D I ++ KGADS V   +Q          H+ ++   T+ ++   A +G R
Sbjct: 750  SVVIRHPLTDEINVYTKGADSVVMDLLQPCSSVDARGRHQKKIRSKTQNYLNVYAAEGLR 809

Query: 598  TLCVAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQD 657
            TLC+A + ++ ++Y    +  +EA+ +L++ EE + +    +ETN++L+GAT +ED+LQD
Sbjct: 810  TLCIAKRVLSKEEYACWLQSHLEAESSLENSEELLFQSAIRLETNLHLLGATGIEDRLQD 869

Query: 658  QAAETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERKEDR 717
               ETI  L  AGL++WVLTGDK ETA +  YAC+L   + E++ L   + E      D 
Sbjct: 870  GVPETISKLRQAGLQIWVLTGDKQETAVNIAYACKLLDHDEEVITLNATSQEACAALLD- 928

Query: 718  LHELLIEYRKKLLHEFPKSTRSF-----------KKAWTEHQEYGLIIDGSTLSLILNSS 766
              + L   + + L   P+ T+               +    +   L+IDG +L+  L   
Sbjct: 929  --QCLCYVQSRGLQRAPEKTKGKVSMRFSSLCPPSTSTASGRRPSLVIDGRSLAYALEK- 985

Query: 767  QDSSSNNYKSIFLQICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSM 826
                  N +  FL +  +C +VLCCR  PLQK+ +V++V++ K   +TL+IGDGANDVSM
Sbjct: 986  ------NLEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLVRS-KLKAMTLAIGDGANDVSM 1038

Query: 827  ILESHVGIGIKGKEGRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLC 886
            I  + VG+GI G+EG QA   SD++VPKF++L++LL+ HGH  Y R+A++V YFFYKN  
Sbjct: 1039 IQVADVGVGISGQEGMQAVMASDFAVPKFRYLERLLILHGHWCYSRLANMVLYFFYKNTM 1098

Query: 887  FILPQFLYQFFCGFSQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPRLYM 946
            F+   F +QFFCGFS   + D  YL  +N+ F+SLP L   +L++ +  + L ++P+LY 
Sbjct: 1099 FVGLLFWFQFFCGFSASTMIDQWYLIFFNLLFSSLPPLVTGVLDRDVPANVLLTNPQLYK 1158

Query: 947  KISGNAMLQLGPFLYWTFL--AAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFGTIVFT 1004
              SG  M +  P  +W  +  AAF+  V F   Y  +  ++++        +T+GT + T
Sbjct: 1159 --SGQNMEEYRPRTFWFNMADAAFQSLVCFSIPYLAYYDSNVD-------LFTWGTPIVT 1209

Query: 1005 VLVFTVTLKLALDTRFWTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQQRMYFVFAQML 1064
            + + T  L L ++T+ WTW+N      S+  +   +  +             Y+    +L
Sbjct: 1210 IALLTFLLHLGIETKTWTWLNWITCGFSVLLFFTVALIYNASCATCYPPSNPYWTMQALL 1269

Query: 1065 SSVSTWLAIILLIFISLFPEI 1085
                 +L  ++    +L P +
Sbjct: 1270 GDPVFYLTCLMTPVAALLPRL 1290



 Score =  264 bits (675), Expect = 3e-70
 Identities = 151/401 (37%), Positives = 233/401 (58%), Gaps = 13/401 (3%)

Query: 40  AQRFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLVQ-VTVDTPTSPVTSGLPL 98
           AQ   DNR+ ++KYTL +FLPKNLFEQF R AN YF+ I L+  V       P  +  P+
Sbjct: 56  AQHLADNRLKTTKYTLLSFLPKNLFEQFHRPANVYFVFIALLNFVPAVNAFQPGLALAPV 115

Query: 99  FFVITVTAIKQGYEDWLRHRADNEVNK--STVYIIENAKRVRKESEKIKVGDVVEVQADE 156
            F++ +TA +  +ED+ RHR+D+++N     V+  E  K V +  ++I VGD V ++ +E
Sbjct: 116 LFILAITAFRDLWEDYSRHRSDHKINHLGCLVFSREEKKYVNRFWKEIHVGDFVRLRCNE 175

Query: 157 TFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIALCTAESIDTLRAAIECEQ 216
            FP D++LLSS   DG C++ TA+LDGE+N K    VR    L +  +  T  + IECE+
Sbjct: 176 IFPADILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNPLTFTSVIECEK 235

Query: 217 PQPDLYKFVGRINIYSNSLEAVARSLGPENLLLKGATLKNTEKIYGVAVYTGMETKMALN 276
           P  DL +F G I I+ N  +A    L  ENLLL+G TL+NT+ + G+ +Y G ETK  LN
Sbjct: 236 PNNDLSRFRGCI-IHDNGKKA---GLYKENLLLRGCTLRNTDAVVGIVIYAGHETKALLN 291

Query: 277 YQGKSQKRSAVEKSINAFLI--VYLFILLTKAAVCTTLKYVWQSTPYNDEPWYNQKTQKE 334
             G   KRS +E+ +N  ++  V L + ++  +      ++W+   Y ++       + +
Sbjct: 292 NSGPRYKRSKLERQMNCDVLWCVLLLVCMSLFSAVGHGLWIWR---YQEKKSLFYVPKSD 348

Query: 335 RETLK-VLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFISWDKDFYDEEINEGAL 393
             +L  V      FL+ +++   +IP+S+YV++E+ K    +FI+ D   YDEE +    
Sbjct: 349 GSSLSPVTAAVYSFLTMIIVLQVLIPISLYVSIEIVKACQVYFINQDMQLYDEETDSQLQ 408

Query: 394 VNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKY 434
               ++ E+LGQ+ Y+F+DKTGTLTEN M F  C + G +Y
Sbjct: 409 CRALNITEDLGQIQYIFSDKTGTLTENKMVFRRCTVSGVEY 449


>gi|55743077 ATPase, class I, type 8B, member 2 isoform b [Homo
           sapiens]
          Length = 387

 Score =  173 bits (439), Expect = 7e-43
 Identities = 98/328 (29%), Positives = 169/328 (51%), Gaps = 16/328 (4%)

Query: 42  RFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLVQVTVDTPT-SPVTSGLPLFF 100
           ++  N I +SKY +  FLP NLFEQF+ +AN YFL + ++Q+     + S  T+ +PL  
Sbjct: 28  QYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVL 87

Query: 101 VITVTAIKQGYEDWLRHRADNEVNKSTVYIIENAKRVRKESEKIKVGDVVEVQADETFPC 160
           V+T+TA+K   +D+ RH++DN+VN     ++ N    +++   + VGD+++++ ++    
Sbjct: 88  VLTITAVKDATDDYFRHKSDNQVNNRQSQVLINGILQQEQWMNVCVGDIIKLENNQFVAA 147

Query: 161 DLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIALCTAESIDTLRAAIECEQPQPD 220
           DL+LLSS    G CY+ TA LDGE+N K   A+  T  L     +      + CE P   
Sbjct: 148 DLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGDISKLAKFDGEVICEPPNNK 207

Query: 221 LYKFVGRINIYSNSLEAVARSLGPENLLLKGATLKNTEKIYGVAVYTGMETKMALNYQGK 280
           L KF G +    N        L  +N+LL+G  L+NTE  +G+ ++ G +TK+  N    
Sbjct: 208 LDKFSGTLYWKENKF-----PLSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRT 262

Query: 281 SQKRSAVEKSINAFLIVYLFILLTKAAVCTTLKYVWQSTP----YNDEPWYNQKTQKERE 336
             KR+++++ +N  ++     L+    +      +W+           PW       E  
Sbjct: 263 KFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGMRFQVYLPW------DEAV 316

Query: 337 TLKVLKMFTDFLSFMVLFNFIIPVSMYV 364
                  F  F S++++ N ++P+S+YV
Sbjct: 317 DSAFFSGFLSFWSYIIILNTVVPISLYV 344


>gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo
           sapiens]
          Length = 1170

 Score = 85.1 bits (209), Expect = 3e-16
 Identities = 136/661 (20%), Positives = 243/661 (36%), Gaps = 118/661 (17%)

Query: 95  GLPLFFVITVTAIKQGYEDW--------LRHRADNEVNKSTVYIIENAKRVRKESEKIKV 146
           G  + F + +  +   + DW        L+ R + E   S   II N + ++    +I V
Sbjct: 152 GAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQKFS---IIRNGQLIQLPVAEIVV 208

Query: 147 GDVVEVQADETFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIALCTAESID 206
           GD+ +V+  +  P D IL+          +  +SL GES+       +D + L     ++
Sbjct: 209 GDIAQVKYGDLLPADGILIQG----NDLKIDESSLTGESDHVKKSLDKDPMLLSGTHVME 264

Query: 207 ----TLRAAIECEQPQPDLYKFVGRINIYSNSLEAVARSLG-PENLLLKGATLKNTEKIY 261
                +  A+        +   +G         +   +  G PEN        +N  K  
Sbjct: 265 GSGRMVVTAVGVNSQTGIILTLLGVNEDDEGEKKKKGKKQGVPEN--------RNKAKTQ 316

Query: 262 -GVAV-YTGMETKMALNYQGKSQKRSAV---EKSINAFLIVYLFILLTKAAVCTT----- 311
            GVA+    + ++  ++ + K +K   V   EKS+    +  L + + KA +  +     
Sbjct: 317 DGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKLTRLAVQIGKAGLLMSALTVF 376

Query: 312 ---LKYVWQSTPYNDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPVSMYVTVEM 368
              L +V  +   N  PW  + T               ++ + V F FII +++ V    
Sbjct: 377 ILILYFVIDNFVINRRPWLPECTPI-------------YIQYFVKF-FIIGITVLVVAVP 422

Query: 369 QKFLGSFFISWDKDFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECC 428
           +    +  IS       + + +  LV   D  E +G    + +DKTGTLT N M  ++  
Sbjct: 423 EGLPLAVTISLAYSV-KKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAY 481

Query: 429 IDGHKYKGVTQEVDGLSQTDGTLTYFDKVDKNREELFLRALCLCHTVEIKTNDAVDGATE 488
           I G  Y+ +                         ++FL  +       I  N A      
Sbjct: 482 IGGIHYRQIPSP----------------------DVFLPKVLDLIVNGISINSAYTSKIL 519

Query: 489 SAELTYISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRR 548
             E       P ++         GF     +  Y  V N   E+ E +L     F++VR+
Sbjct: 520 PPEKE--GGLPRQVGNKTECALLGFV-TDLKQDYQAVRN---EVPEEKLYKVYTFNSVRK 573

Query: 549 RMSVIVKTQEGDILLFCKGADSAVF--------------PRVQNHEIELTKVHVERNAMD 594
            MS +++   G   ++ KGA   +               P       ++ +  +E  A D
Sbjct: 574 SMSTVIRNPNGGFRMYSKGASEIILRKCNRILDRKGEAVPFKNKDRDDMVRTVIEPMACD 633

Query: 595 GYRTLCVAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDK 654
           G RT+C+A+++   DD E              D E       ++I T +  I    +ED 
Sbjct: 634 GLRTICIAYRDF--DDTE-----------PSWDNE-------NEILTELTCIAVVGIEDP 673

Query: 655 LQDQAAETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERK 714
           ++ +  + I     AG+ V ++TGD + TA++    C +     + L L  K      R 
Sbjct: 674 VRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFLCLEGKEFNRLIRN 733

Query: 715 E 715
           E
Sbjct: 734 E 734


>gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo
           sapiens]
          Length = 1205

 Score = 85.1 bits (209), Expect = 3e-16
 Identities = 136/661 (20%), Positives = 243/661 (36%), Gaps = 118/661 (17%)

Query: 95  GLPLFFVITVTAIKQGYEDW--------LRHRADNEVNKSTVYIIENAKRVRKESEKIKV 146
           G  + F + +  +   + DW        L+ R + E   S   II N + ++    +I V
Sbjct: 152 GAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQKFS---IIRNGQLIQLPVAEIVV 208

Query: 147 GDVVEVQADETFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIALCTAESID 206
           GD+ +V+  +  P D IL+          +  +SL GES+       +D + L     ++
Sbjct: 209 GDIAQVKYGDLLPADGILIQG----NDLKIDESSLTGESDHVKKSLDKDPMLLSGTHVME 264

Query: 207 ----TLRAAIECEQPQPDLYKFVGRINIYSNSLEAVARSLG-PENLLLKGATLKNTEKIY 261
                +  A+        +   +G         +   +  G PEN        +N  K  
Sbjct: 265 GSGRMVVTAVGVNSQTGIILTLLGVNEDDEGEKKKKGKKQGVPEN--------RNKAKTQ 316

Query: 262 -GVAV-YTGMETKMALNYQGKSQKRSAV---EKSINAFLIVYLFILLTKAAVCTT----- 311
            GVA+    + ++  ++ + K +K   V   EKS+    +  L + + KA +  +     
Sbjct: 317 DGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKLTRLAVQIGKAGLLMSALTVF 376

Query: 312 ---LKYVWQSTPYNDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPVSMYVTVEM 368
              L +V  +   N  PW  + T               ++ + V F FII +++ V    
Sbjct: 377 ILILYFVIDNFVINRRPWLPECTPI-------------YIQYFVKF-FIIGITVLVVAVP 422

Query: 369 QKFLGSFFISWDKDFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECC 428
           +    +  IS       + + +  LV   D  E +G    + +DKTGTLT N M  ++  
Sbjct: 423 EGLPLAVTISLAYSV-KKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAY 481

Query: 429 IDGHKYKGVTQEVDGLSQTDGTLTYFDKVDKNREELFLRALCLCHTVEIKTNDAVDGATE 488
           I G  Y+ +                         ++FL  +       I  N A      
Sbjct: 482 IGGIHYRQIPSP----------------------DVFLPKVLDLIVNGISINSAYTSKIL 519

Query: 489 SAELTYISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRR 548
             E       P ++         GF     +  Y  V N   E+ E +L     F++VR+
Sbjct: 520 PPEKE--GGLPRQVGNKTECALLGFV-TDLKQDYQAVRN---EVPEEKLYKVYTFNSVRK 573

Query: 549 RMSVIVKTQEGDILLFCKGADSAVF--------------PRVQNHEIELTKVHVERNAMD 594
            MS +++   G   ++ KGA   +               P       ++ +  +E  A D
Sbjct: 574 SMSTVIRNPNGGFRMYSKGASEIILRKCNRILDRKGEAVPFKNKDRDDMVRTVIEPMACD 633

Query: 595 GYRTLCVAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDK 654
           G RT+C+A+++   DD E              D E       ++I T +  I    +ED 
Sbjct: 634 GLRTICIAYRDF--DDTE-----------PSWDNE-------NEILTELTCIAVVGIEDP 673

Query: 655 LQDQAAETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERK 714
           ++ +  + I     AG+ V ++TGD + TA++    C +     + L L  K      R 
Sbjct: 674 VRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFLCLEGKEFNRLIRN 733

Query: 715 E 715
           E
Sbjct: 734 E 734


>gi|66932949 ATPase type 13A4 [Homo sapiens]
          Length = 1196

 Score = 83.2 bits (204), Expect = 1e-15
 Identities = 136/673 (20%), Positives = 267/673 (39%), Gaps = 126/673 (18%)

Query: 404  GQVDYVFTDKTGTLTENSMEF---IECCIDGHKYKGVTQEVDGLSQTDGTLTYFDKVDKN 460
            GQ++ V  DKTGTLT + ++    + C  D + ++ V     G +   G L         
Sbjct: 478  GQLNLVCFDKTGTLTRDGLDLWGVVSC--DRNGFQEVHSFASGQALPWGPLC-------- 527

Query: 461  REELFLRALCLCHTVEIKTNDAVDGATESAELTYISSSPDEIAL------VKGAKRYGFT 514
                   A+  CH++ I  +  + G  +  +L    ++  E+A       +KG   +   
Sbjct: 528  ------AAMASCHSL-ILLDGTIQG--DPLDLKMFEATTWEMAFSGDDFHIKGVPAHAMV 578

Query: 515  FLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRRRMSVIVKTQEGDILLFCKGADSAVFP 574
                R         +  +E   +LH   F +  +RM+VIV+   GD L F KGA   V  
Sbjct: 579  VKPCRTA------SQVPVEGIAILHQFPFSSALQRMTVIVQEMGGDRLAFMKGAPERVAS 632

Query: 575  RVQNHEIELTKV-HVERNAMDGYRTLCVAFKEIAPDDYERINRQLIEAKMALQDREEKME 633
              Q   +  + V  ++     G+R + +A+K++  D +     +                
Sbjct: 633  FCQPETVPTSFVSELQIYTTQGFRVIALAYKKLENDHHATTLTR---------------- 676

Query: 634  KVFDDIETNMNLIGATAVEDKLQDQAAETIEALHAAGLKVWVLTGDKMETAKSTCYACRL 693
               + +E+++  +G   +E++L+++    +E L +A ++  ++TGD ++TA +      +
Sbjct: 677  ---ETVESDLIFLGLLILENRLKEETKPVLEELISARIRTVMITGDNLQTAITVARKSGM 733

Query: 694  FQTNTELLELTTKTIEESERKEDRLHELLIEYRKKLLHEFPKSTRSFKKAWTEHQEYGLI 753
               + +++ +     E +      +   L+E +K +++    +  + +   ++       
Sbjct: 734  VSESQKVILIEAN--ETTGSSSASISWTLVEEKKHIMYGNQDNYINIRDEVSDKGR---- 787

Query: 754  IDGSTLSLILNSSQDSSSNNYKSIFLQICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPI 813
             +GS    +   S    S ++ S+  +I +  T  +  RM+P QK+ +V   + L     
Sbjct: 788  -EGSYHFALTGKSFHVISQHFSSLLPKILINGT--IFARMSPGQKSSLVEEFQKL--DYF 842

Query: 814  TLSIGDGANDVSMILESHVGIGIKGKEGRQAA--RNSDYSVPKFKHLKK-----LLLAHG 866
                GDGAND   +  +HVGI +  +E   A+   +   ++    HL K     L+ +  
Sbjct: 843  VGMCGDGANDCGALKMAHVGISLSEQEASVASPFTSKTPNIECVPHLIKEGRAALVTSFC 902

Query: 867  HLYYVRIAHLVQY-----FFYKNLCFILPQFLYQ-----FFCGFSQQ---------PLYD 907
               Y+ +  ++QY      +++       QFL+Q        G +           P   
Sbjct: 903  MFKYMALYSMIQYVGVLLLYWETNSLSNYQFLFQDLAITTLIGVTMNLNGAYPKLVPFRP 962

Query: 908  AAYL--------TMYNICFT-SLPILAYSLLE---------------QHINIDTLTSDPR 943
            A  L         ++NI  + ++ I  + L++               Q+ +I  LT  P 
Sbjct: 963  AGRLISPPLLLSVIFNILLSLAMHIAGFILVQRQPWYSVEIHSACTVQNESISELTMSPT 1022

Query: 944  LYMKISGNAMLQLGPFLYWTFLAAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFGTIVF 1003
               K+  N+          TF +    TV+F GT      A +   GK +   T+   +F
Sbjct: 1023 APEKMESNS----------TFTSFENTTVWFLGTINCITVALVFSKGKPFRQPTYTNYIF 1072

Query: 1004 TVLVFTVTLKLAL 1016
             VLV  + L + L
Sbjct: 1073 -VLVLIIQLGVCL 1084


>gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo
           sapiens]
          Length = 1198

 Score = 80.1 bits (196), Expect = 1e-14
 Identities = 135/659 (20%), Positives = 243/659 (36%), Gaps = 132/659 (20%)

Query: 96  LPLFFVITVTAIKQGYEDWLRHRA----DNEVNKSTVYIIENAKRVRK-ESEKIKVGDVV 150
           L +  V+ VTA    + DW + +      + + +   + +  A +V +    +I VGD+ 
Sbjct: 159 LSVICVVLVTA----FNDWSKEKQFRGLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIA 214

Query: 151 EVQADETFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIALCTAESID---- 206
           +V+  +  P D + +          +  +SL GES+       +D + L     ++    
Sbjct: 215 QVKYGDLLPADGLFIQG----NDLKIDESSLTGESDQVRKSVDKDPMLLSGTHVMEGSGR 270

Query: 207 TLRAAIECEQPQPDLYKFVGRINIYSNSLEAVARSLGPENLLLKGATLKNTEKIYGVAVY 266
            L  A+        ++  +G                G E    K    K  +   G A  
Sbjct: 271 MLVTAVGVNSQTGIIFTLLGA---------------GGEEEEKKDKKAKQQD---GAAAM 312

Query: 267 TGMETKMALNYQGKSQKRSAV---EKSINAFLIVYLFILLTKAA--------VCTTLKYV 315
                K A       +K++++   EKS+    +  L + + KA         +   L + 
Sbjct: 313 EMQPLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFT 372

Query: 316 WQSTPYNDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSF 375
             +   N +PW  + T               ++ + V F FII V++ V    +    + 
Sbjct: 373 VDTFVVNKKPWLPECTPV-------------YVQYFVKF-FIIGVTVLVVAVPEGLPLAV 418

Query: 376 FISWDKDFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKYK 435
            IS       + + +  LV   D  E +G    + +DKTGTLT N M  ++  +    YK
Sbjct: 419 TISLAYSV-KKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYK 477

Query: 436 GVTQEVDGLSQTDGTLTYFDKVDKNREELFLRALCL--CHTVEIKTNDAVDGATESAELT 493
            +                   ++    EL + A+ +   +T +I   +  +GA       
Sbjct: 478 EIPDP--------------SSINTKTMELLINAIAINSAYTTKILPPEK-EGAL------ 516

Query: 494 YISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRRRMSVI 553
                P ++         GF  L  +  Y   E  R ++ E +L     F++VR+ MS +
Sbjct: 517 -----PRQVGNKTECGLLGFV-LDLKQDY---EPVRSQMPEEKLYKVYTFNSVRKSMSTV 567

Query: 554 VKTQEGDILLFCKGADSAVF------------PRV--QNHEIELTKVHVERNAMDGYRTL 599
           +K  +    ++ KGA   V             PRV       E+ K  +E  A DG RT+
Sbjct: 568 IKLPDESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMACDGLRTI 627

Query: 600 CVAFKEI--APD-DYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQ 656
           CVA+++   +P+ D++  N                      DI   +  I    +ED ++
Sbjct: 628 CVAYRDFPSSPEPDWDNEN----------------------DILNELTCICVVGIEDPVR 665

Query: 657 DQAAETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERKE 715
            +  E I     AG+ V ++TGD + TA++    C +     + L L  K      R E
Sbjct: 666 PEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNE 724


>gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo
           sapiens]
          Length = 1176

 Score = 79.0 bits (193), Expect = 2e-14
 Identities = 80/342 (23%), Positives = 131/342 (38%), Gaps = 60/342 (17%)

Query: 388 INEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKYKGVTQEVDGLSQT 447
           + +  LV   D  E +G    + +DKTGTLT N M  ++  I+   YK V +        
Sbjct: 451 MKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYINEKHYKKVPEP------- 503

Query: 448 DGTLTYFDKVDKNREELFLRALCLCHTVEIKTNDAVDGATESAELTYISSSPDEIALVKG 507
                  + +  N     L  L    +V       +    +   L     +  E AL+  
Sbjct: 504 -------EAIPPN----ILSYLVTGISVNCAYTSKILPPEKEGGLPRHVGNKTECALLG- 551

Query: 508 AKRYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRRRMSVIVKTQEGDILLFCKG 567
                   L  +  Y  V N   EI E  L     F++VR+ MS ++K  +G   +F KG
Sbjct: 552 ------LLLDLKRDYQDVRN---EIPEEALYKVYTFNSVRKSMSTVLKNSDGSYRIFSKG 602

Query: 568 ADSAVFPRV-----QNHEI---------ELTKVHVERNAMDGYRTLCVAFKEIAPDDYER 613
           A   +  +       N E          ++ K  +E  A +G RT+C+AF++    + E 
Sbjct: 603 ASEIILKKCFKILSANGEAKVFRPRDRDDIVKTVIEPMASEGLRTICLAFRDFPAGEPE- 661

Query: 614 INRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAAETIEALHAAGLKV 673
                        D E       +DI T +  I    +ED ++ +  + I+    AG+ V
Sbjct: 662 ----------PEWDNE-------NDIVTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITV 704

Query: 674 WVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERKE 715
            ++TGD + TA++    C +     + L L  K      R E
Sbjct: 705 RMVTGDNINTARAIATKCGILHPGEDFLCLEGKDFNRRIRNE 746


>gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo
           sapiens]
          Length = 1220

 Score = 79.0 bits (193), Expect = 2e-14
 Identities = 80/342 (23%), Positives = 131/342 (38%), Gaps = 60/342 (17%)

Query: 388 INEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKYKGVTQEVDGLSQT 447
           + +  LV   D  E +G    + +DKTGTLT N M  ++  I+   YK V +        
Sbjct: 451 MKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYINEKHYKKVPEP------- 503

Query: 448 DGTLTYFDKVDKNREELFLRALCLCHTVEIKTNDAVDGATESAELTYISSSPDEIALVKG 507
                  + +  N     L  L    +V       +    +   L     +  E AL+  
Sbjct: 504 -------EAIPPN----ILSYLVTGISVNCAYTSKILPPEKEGGLPRHVGNKTECALLG- 551

Query: 508 AKRYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRRRMSVIVKTQEGDILLFCKG 567
                   L  +  Y  V N   EI E  L     F++VR+ MS ++K  +G   +F KG
Sbjct: 552 ------LLLDLKRDYQDVRN---EIPEEALYKVYTFNSVRKSMSTVLKNSDGSYRIFSKG 602

Query: 568 ADSAVFPRV-----QNHEI---------ELTKVHVERNAMDGYRTLCVAFKEIAPDDYER 613
           A   +  +       N E          ++ K  +E  A +G RT+C+AF++    + E 
Sbjct: 603 ASEIILKKCFKILSANGEAKVFRPRDRDDIVKTVIEPMASEGLRTICLAFRDFPAGEPE- 661

Query: 614 INRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAAETIEALHAAGLKV 673
                        D E       +DI T +  I    +ED ++ +  + I+    AG+ V
Sbjct: 662 ----------PEWDNE-------NDIVTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITV 704

Query: 674 WVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERKE 715
            ++TGD + TA++    C +     + L L  K      R E
Sbjct: 705 RMVTGDNINTARAIATKCGILHPGEDFLCLEGKDFNRRIRNE 746


>gi|48255951 plasma membrane calcium ATPase 2 isoform 1 [Homo
           sapiens]
          Length = 1243

 Score = 77.8 bits (190), Expect = 5e-14
 Identities = 80/347 (23%), Positives = 135/347 (38%), Gaps = 71/347 (20%)

Query: 388 INEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKYKGVTQEVDGLSQT 447
           + +  LV   D  E +G    + +DKTGTLT N M  ++  +    YK +          
Sbjct: 475 MKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIPDP------- 527

Query: 448 DGTLTYFDKVDKNREELFLRALCL--CHTVEIKTNDAVDGATESAELTYISSSPDEIALV 505
                    ++    EL + A+ +   +T +I   +  +GA            P ++   
Sbjct: 528 -------SSINTKTMELLINAIAINSAYTTKILPPEK-EGAL-----------PRQVGNK 568

Query: 506 KGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRRRMSVIVKTQEGDILLFC 565
                 GF  L  +  Y   E  R ++ E +L     F++VR+ MS ++K  +    ++ 
Sbjct: 569 TECGLLGFV-LDLKQDY---EPVRSQMPEEKLYKVYTFNSVRKSMSTVIKLPDESFRMYS 624

Query: 566 KGADSAVF------------PRV--QNHEIELTKVHVERNAMDGYRTLCVAFKEI--APD 609
           KGA   V             PRV       E+ K  +E  A DG RT+CVA+++   +P+
Sbjct: 625 KGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMACDGLRTICVAYRDFPSSPE 684

Query: 610 -DYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAAETIEALHA 668
            D++  N                      DI   +  I    +ED ++ +  E I     
Sbjct: 685 PDWDNEN----------------------DILNELTCICVVGIEDPVRPEVPEAIRKCQR 722

Query: 669 AGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERKE 715
           AG+ V ++TGD + TA++    C +     + L L  K      R E
Sbjct: 723 AGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNE 769


>gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo
           sapiens]
          Length = 1220

 Score = 74.7 bits (182), Expect = 5e-13
 Identities = 76/344 (22%), Positives = 135/344 (39%), Gaps = 65/344 (18%)

Query: 388 INEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKYKGVTQEVDGLSQT 447
           + +  LV   D  E +G    + +DKTGTLT N M  ++  +    YK    E+   S  
Sbjct: 449 MKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQSYLGDTHYK----EIPAPSAL 504

Query: 448 DGTLTYFDKVDKNREELFLRALCL--CHTVEIKTNDAVDGATESAELTYISSSPDEIALV 505
              +           +L + A+ +   +T +I   +  +GA            P ++   
Sbjct: 505 TPKIL----------DLLVHAISINSAYTTKILPPEK-EGAL-----------PRQVGNK 542

Query: 506 KGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRRRMSVIVKTQEGDILLFC 565
                 GF     R+     +  R++I E +L     F++VR+ MS +++  +G   LF 
Sbjct: 543 TECALLGFVLDLKRD----FQPVREQIPEDKLYKVYTFNSVRKSMSTVIRMPDGGFRLFS 598

Query: 566 KGADSAVFPRVQN--------------HEIELTKVHVERNAMDGYRTLCVAFKEIAPDDY 611
           KGA   +  +  N                 ++ +  +E  A DG RT+C+A+++ +    
Sbjct: 599 KGASEILLKKCTNILNSNGELRGFRPRDRDDMVRKIIEPMACDGLRTICIAYRDFSAGQE 658

Query: 612 ERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAAETIEALHAAGL 671
                          D + + E V D     +  I    +ED ++ +  E I     AG+
Sbjct: 659 P--------------DWDNENEVVGD-----LTCIAVVGIEDPVRPEVPEAIRKCQRAGI 699

Query: 672 KVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERKE 715
            V ++TGD + TA++    C + Q   + L L  K      R E
Sbjct: 700 TVRMVTGDNINTARAIAAKCGIIQPGEDFLCLEGKEFNRRIRNE 743


>gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo
           sapiens]
          Length = 1173

 Score = 74.7 bits (182), Expect = 5e-13
 Identities = 76/344 (22%), Positives = 135/344 (39%), Gaps = 65/344 (18%)

Query: 388 INEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKYKGVTQEVDGLSQT 447
           + +  LV   D  E +G    + +DKTGTLT N M  ++  +    YK    E+   S  
Sbjct: 449 MKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQSYLGDTHYK----EIPAPSAL 504

Query: 448 DGTLTYFDKVDKNREELFLRALCL--CHTVEIKTNDAVDGATESAELTYISSSPDEIALV 505
              +           +L + A+ +   +T +I   +  +GA            P ++   
Sbjct: 505 TPKIL----------DLLVHAISINSAYTTKILPPEK-EGAL-----------PRQVGNK 542

Query: 506 KGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRRRMSVIVKTQEGDILLFC 565
                 GF     R+     +  R++I E +L     F++VR+ MS +++  +G   LF 
Sbjct: 543 TECALLGFVLDLKRD----FQPVREQIPEDKLYKVYTFNSVRKSMSTVIRMPDGGFRLFS 598

Query: 566 KGADSAVFPRVQN--------------HEIELTKVHVERNAMDGYRTLCVAFKEIAPDDY 611
           KGA   +  +  N                 ++ +  +E  A DG RT+C+A+++ +    
Sbjct: 599 KGASEILLKKCTNILNSNGELRGFRPRDRDDMVRKIIEPMACDGLRTICIAYRDFSAGQE 658

Query: 612 ERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAAETIEALHAAGL 671
                          D + + E V D     +  I    +ED ++ +  E I     AG+
Sbjct: 659 P--------------DWDNENEVVGD-----LTCIAVVGIEDPVRPEVPEAIRKCQRAGI 699

Query: 672 KVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERKE 715
            V ++TGD + TA++    C + Q   + L L  K      R E
Sbjct: 700 TVRMVTGDNINTARAIAAKCGIIQPGEDFLCLEGKEFNRRIRNE 743


>gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens]
          Length = 1039

 Score = 67.4 bits (163), Expect = 7e-11
 Identities = 127/601 (21%), Positives = 219/601 (36%), Gaps = 97/601 (16%)

Query: 390 EGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKYKGVTQEVDGLSQTDG 449
           +  LV   +  E LG    + +DKTGTLT+N M       D   +   T E       D 
Sbjct: 369 KNCLVKNLEAVETLGSTSIICSDKTGTLTQNRMTVAHLWFDNQIFVADTSE-------DH 421

Query: 450 TLTYFDKVDKNREELFLRALCLCHTVEIKTNDAVDGATESAELTYISSSPDEIALVKGAK 509
           +   FD+  +    L  + + LC+  E K         + A    +     E AL+K   
Sbjct: 422 SNQVFDQSSRTWASLS-KIITLCNRAEFKPGQENVPIMKKA----VIGDASETALLK--- 473

Query: 510 RYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRRRMSVIVKTQEGDILLFCKGAD 569
            +    LG+    M +  + +++ E     T  F      M           L+  KGA 
Sbjct: 474 -FSEVILGD---VMEIRKRNRKVAEIPFNSTNKFQLSIHEMD---DPHGKRFLMVMKGAP 526

Query: 570 SAVFPRVQNHEIELTKVHVERNAMDGYRTLCVAFKEIAPDDYERINRQLIEAKMALQDRE 629
             +  +     I   +  ++++    + T   A+ E+       +  +++         +
Sbjct: 527 ERILEKCSTIMINGEEHPLDKSTAKTFHT---AYMELGG-----LGERVLGFCHLYLPAD 578

Query: 630 EKMEKVFDDIE------TNMNLIGATAVEDKLQDQAAETIEALHAAGLKVWVLTGDKMET 683
           E  E    DI+      +N+  +G  ++ D  +    + +    +AG+KV ++TGD   T
Sbjct: 579 EFPETYSFDIDAMNFPTSNLCFVGLLSMIDPPRSTVPDAVTKCRSAGIKVIMVTGDHPIT 638

Query: 684 AKSTCYACRLFQTNTELLELTTKTIEESERKEDRLHELLIEYRKKLLHEFPKSTRSFKKA 743
           AK+   +  +   N+E +E             D  H L I   +        + R  K A
Sbjct: 639 AKAIAKSVGIISANSETVE-------------DIAHRLNIAVEQV-------NKRDAKAA 678

Query: 744 WTEHQEYGLIIDGSTLSLILNSSQDSSSNNYKSIFLQICMKCTAVLCCRMAPLQKAQIVR 803
                    ++ G  L  + +   D    NY+ I              R +P QK  IV 
Sbjct: 679 ---------VVTGMELKDMSSEQLDEILANYQEIVF-----------ARTSPQQKLIIVE 718

Query: 804 MVKNLKGSPITLSIGDGANDVSMILESHVGIGIKGKEGRQAARNSDYSVPKFKHLKKLL- 862
             +  +   +    GDG ND   + ++ +GI + G  G  AA+N+   V    +   ++ 
Sbjct: 719 GCQ--RQDAVVAVTGDGVNDSPALKKADIGIAM-GIAGSDAAKNAADMVLLDDNFASIVT 775

Query: 863 -LAHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCGFSQQPLYDAAYLTMYNICFTSL 921
            +  G L +  +   + Y   KN+  + P FL     G    PL       ++    T +
Sbjct: 776 GVEEGRLIFDNLKKTIAYSLTKNIAELCP-FLIYIIVGL---PLPIGTITILFIDLGTDI 831

Query: 922 ---PILAYSLLE--------QHINIDTLTSDP-RLYMKISGNAMLQLGPFLYWTFLAAFE 969
                LAY   E        +H N D L + P  +Y  +    M  LG FL +  + A E
Sbjct: 832 IPSIALAYEKAESDIMNRKPRHKNKDRLVNQPLAVYSYLHIGLMQALGAFLVYFTVYAQE 891

Query: 970 G 970
           G
Sbjct: 892 G 892



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 35/121 (28%), Positives = 57/121 (47%), Gaps = 9/121 (7%)

Query: 70  IANFYFLIIFLVQVTVDTPTS--PVTSGLPLFFVITVTAIKQGYEDWLRHRADNEVNK-- 125
           +  F   I + +Q + D   S   V  G  L  V+ +T I   Y++       +  NK  
Sbjct: 121 VGAFLCWIAYGIQYSSDKSASLNNVYLGCVLGLVVILTGIFAYYQEAKSTNIMSSFNKMI 180

Query: 126 -STVYIIENAKRVRKESEKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTASLDGE 184
                +I ++++    SE++ VGD+VEV+  +  P D+ +LSS      C V  +SL GE
Sbjct: 181 PQQALVIRDSEKKTIPSEQLVVGDIVEVKGGDQIPADIRVLSS----QGCRVDNSSLTGE 236

Query: 185 S 185
           S
Sbjct: 237 S 237


>gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo
           sapiens]
          Length = 1029

 Score = 67.0 bits (162), Expect = 9e-11
 Identities = 166/828 (20%), Positives = 297/828 (35%), Gaps = 210/828 (25%)

Query: 56  WNFLPKNLFEQFRRIANFYFLIIFLV-QVTVDTPTSPVTSGLPLFFVITVTAIKQGYEDW 114
           W    K LF  F  +     ++ F+   + +     P    L L  V++V  I  G   +
Sbjct: 97  WVKFCKQLFGGFSLLLWTGAILCFVAYSIQIYFNEEPTKDNLYLSIVLSVVVIVTGCFSY 156

Query: 115 LRHRADNEVNKS-------TVYIIENAKRVRKESEKIKVGDVVEVQADETFPCDLILLSS 167
            +    +++ +S          +I   ++++   +++ +GD+VE++  +  P DL L+S+
Sbjct: 157 YQEAKSSKIMESFKNMVPQQALVIRGGEKMQINVQEVVLGDLVEIKGGDRVPADLRLISA 216

Query: 168 CTTDGTCYVTTASLDGESNCK------THYAVRDTIALCTAESIDTLRAAIECEQPQPDL 221
                 C V  +SL GES  +      TH    +T  +C   +                 
Sbjct: 217 ----QGCKVDNSSLTGESEPQSRSPDFTHENPLETRNICFFST----------------- 255

Query: 222 YKFVGRINIYSNSLEAVARSLGPENLLLKGATLKNTEKIYGVAVYTGMETKMALNYQGKS 281
                  N    +   +  + G   ++ + A+L +     G+AV             G++
Sbjct: 256 -------NCVEGTARGIVIATGDSTVMGRIASLTS-----GLAV-------------GQT 290

Query: 282 QKRSAVEKSINAFLIVYLFILLTKAAVCTTLKYVWQSTPYNDEPWYNQKTQKERETLKVL 341
              + +E  I+   +V +F+ +T  A+   L Y W                         
Sbjct: 291 PIAAEIEHFIHLITVVAVFLGVTFFALSLLLGYGWLEAII-------------------- 330

Query: 342 KMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFISWDKDFYDEEINEGALVNTSDLNE 401
                FL  +++ N  +P  +  TV +   L +  ++           +  LV   +  E
Sbjct: 331 -----FLIGIIVAN--VPEGLLATVTVCLTLTAKRMA----------RKNCLVKNLEAVE 373

Query: 402 ELGQVDYVFTDKTGTLTENSMEFIECCIDGHKYKG-VTQEVDGLSQTDGTLTYFDKVDKN 460
            LG    + +DKTGTLT+N M       D   Y+   T+E  G + T  + T+F      
Sbjct: 374 TLGSTSTICSDKTGTLTQNRMTVAHMWFDMTVYEADTTEEQTGKTFTKSSDTWF------ 427

Query: 461 REELFLRALCLCHTVEIKTNDAV---------DGATESAELTYISSSPDEIALV--KGAK 509
              +  R   LC+  + K N  +           A+ESA L +I  S   +A +  K  K
Sbjct: 428 ---MLARIAGLCNRADFKANQEILPIAKRATTGDASESALLKFIEQSYSSVAEMREKNPK 484

Query: 510 RYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRRRMSVIVKTQEGDILLFCK--- 566
                F  + N Y    + R++  +  +L              ++K     IL FC    
Sbjct: 485 VAEIPF-NSTNKYQMSIHLREDSSQTHVL--------------MMKGAPERILEFCSTFL 529

Query: 567 ------GADSAVFPRVQNHEIELTKVHVERNAMDGYRTLCVAFKEIAPDDYERINRQLIE 620
                   +  +    QN  +EL  +  ER     +  L  +F +  P + + IN  +  
Sbjct: 530 LNGQEYSMNDEMKEAFQNAYLELGGLG-ERVLGFCFLNLPSSFSKGFPFNTDEINFPM-- 586

Query: 621 AKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAAETIEALHAAGLKVWVLTGDK 680
                                N+  +G  ++ D  +    + +    +AG+KV ++TGD 
Sbjct: 587 --------------------DNLCFVGLISMIDPPRAAVPDAVSKCRSAGIKVIMVTGDH 626

Query: 681 METAKSTCYACRLFQTNTELLELTTKTIEESERKEDRLHELLIEYRKKLLHEFPKSTRSF 740
             TAK+      +    TE  E                     E   +L     K   S 
Sbjct: 627 PITAKAIAKGVGIISEGTETAE---------------------EVAARLKIPISKVDASA 665

Query: 741 KKAWTEHQEYGLIIDGSTLSLILNSSQDSSSNNYKSIFLQICMKCTAVLCCRMAPLQKAQ 800
            KA        +++ G+ L  I +   D    N+  I           +  R +P QK  
Sbjct: 666 AKA--------IVVHGAELKDIQSKQLDQILQNHPEI-----------VFARTSPQQKLI 706

Query: 801 IVRMVKNLKGSPITLSIGDGANDVSMILESHVGI--GIKGKE-GRQAA 845
           IV   + L G+ + ++ GDG ND   + ++ +GI  GI G +  +QAA
Sbjct: 707 IVEGCQRL-GAVVAVT-GDGVNDSPALKKADIGIAMGISGSDVSKQAA 752


>gi|148839292 ATPase type 13A3 [Homo sapiens]
          Length = 1226

 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 77/338 (22%), Positives = 138/338 (40%), Gaps = 57/338 (16%)

Query: 530 KEIEEYELLHTLNFDAVRR--------RMSVIVKTQEGDILL--FCKGADSAVFPRVQNH 579
           +E+E +EL  T     VR+        RMSV+ +   GD  +  + KGA  A+    +  
Sbjct: 607 QEMELFELPATYEIGIVRQFPFSSALQRMSVVARVL-GDRKMDAYMKGAPEAIAGLCKPE 665

Query: 580 EIELTKVHV-ERNAMDGYRTLCVAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDD 638
            + +   +V E     G+R + +A +++             E+K+       K++ +  D
Sbjct: 666 TVPVDFQNVLEDFTKQGFRVIALAHRKL-------------ESKLTWH----KVQNISRD 708

Query: 639 -IETNMNLIGATAVEDKLQDQAAETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTN 697
            IE NM+ +G   +++KL+ +    +E LH A ++  ++TGD M TA S    C +    
Sbjct: 709 AIENNMDFMGLIIMQNKLKQETPAVLEDLHKANIRTVMVTGDSMLTAVSVARDCGMILPQ 768

Query: 698 TELLELTTKTIEESERKEDRLHELLIEYRKKLL----------HEFPKSTRSFKKAWTEH 747
            +++       E    K+ ++ ++   Y   L              P           + 
Sbjct: 769 DKVI-----IAEALPPKDGKVAKINWHYADSLTQCSHPSAIDPEAIPVKLVHDSLEDLQM 823

Query: 748 QEYGLIIDGSTLSLILNSSQDSSSNNYKSIFLQICMKCTAVLCCRMAPLQKAQIVRMVKN 807
             Y   ++G + S+IL   QD          L   +     +  RMAP QK Q++  ++N
Sbjct: 824 TRYHFAMNGKSFSVILEHFQD----------LVPKLMLHGTVFARMAPDQKTQLIEALQN 873

Query: 808 LKGSPITLSIGDGANDVSMILESHVGIGIKGKEGRQAA 845
           +         GDGAND   +  +H GI +   E   A+
Sbjct: 874 V--DYFVGMCGDGANDCGALKRAHGGISLSELEASVAS 909


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.137    0.407 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,025,426
Number of Sequences: 37866
Number of extensions: 1568110
Number of successful extensions: 4584
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 59
Number of HSP's successfully gapped in prelim test: 42
Number of HSP's that attempted gapping in prelim test: 4223
Number of HSP's gapped (non-prelim): 249
length of query: 1119
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1006
effective length of database: 13,968,660
effective search space: 14052471960
effective search space used: 14052471960
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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