Search of human proteins with 58331173

Search of human proteins with 58331173

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|58331173 chaperonin containing TCP1, subunit 6B [Homo
sapiens]
         (530 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|58331173 chaperonin containing TCP1, subunit 6B [Homo sapiens]    1026   0.0  
gi|4502643 chaperonin containing TCP1, subunit 6A isoform a [Hom...   901   0.0  
gi|58331171 chaperonin containing TCP1, subunit 6A isoform b [Ho...   796   0.0  
gi|63162572 chaperonin containing TCP1, subunit 3 isoform a [Hom...   259   4e-69
gi|58761486 chaperonin containing TCP1, subunit 3 isoform b [Hom...   258   9e-69
gi|24307939 chaperonin containing TCP1, subunit 5 (epsilon) [Hom...   251   9e-67
gi|57863257 T-complex protein 1 isoform a [Homo sapiens]              242   5e-64
gi|38455427 chaperonin containing TCP1, subunit 4 (delta) [Homo ...   240   3e-63
gi|5453607 chaperonin containing TCP1, subunit 7 isoform a [Homo...   233   4e-61
gi|58761484 chaperonin containing TCP1, subunit 3 isoform c [Hom...   219   5e-57
gi|5453603 chaperonin containing TCP1, subunit 2 [Homo sapiens]       217   2e-56
gi|48762932 chaperonin containing TCP1, subunit 8 (theta) [Homo ...   173   4e-43
gi|57863259 T-complex protein 1 isoform b [Homo sapiens]              145   9e-35
gi|58331185 chaperonin containing TCP1, subunit 7 isoform b [Hom...   132   1e-30
gi|7657253 T-complex protein 1 [Homo sapiens]                         119   9e-27
gi|41399285 chaperonin [Homo sapiens]                                  60   4e-09
gi|31542947 chaperonin [Homo sapiens]                                  60   4e-09
gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III ...    59   8e-09
gi|100816407 Bardet-Biedl syndrome 10 [Homo sapiens]                   49   1e-05
gi|7705682 geminin [Homo sapiens]                                      32   1.9  
gi|115298659 spectrin, alpha, erythrocytic 1 [Homo sapiens]            30   5.5  
gi|28329436 aprataxin isoform a [Homo sapiens]                         30   7.1  
gi|28329430 aprataxin isoform b [Homo sapiens]                         30   7.1  
gi|52630447 palmitoylated membrane protein 2 [Homo sapiens]            30   7.1  
gi|21450705 leucine rich repeat containing 45 [Homo sapiens]           29   9.3  

>gi|58331173 chaperonin containing TCP1, subunit 6B [Homo sapiens]
          Length = 530

 Score = 1026 bits (2652), Expect = 0.0
 Identities = 530/530 (100%), Positives = 530/530 (100%)

Query: 1   MAAIKAVNSKAEVARARAALAVNICAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDG 60
           MAAIKAVNSKAEVARARAALAVNICAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDG
Sbjct: 1   MAAIKAVNSKAEVARARAALAVNICAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDG 60

Query: 61  NVLLDEMQIQHPTASLIAKVATAQDDVTGDGTTSNVLIIGELLKQADLYISEGLHPRIIA 120
           NVLLDEMQIQHPTASLIAKVATAQDDVTGDGTTSNVLIIGELLKQADLYISEGLHPRIIA
Sbjct: 61  NVLLDEMQIQHPTASLIAKVATAQDDVTGDGTTSNVLIIGELLKQADLYISEGLHPRIIA 120

Query: 121 EGFEAAKIKALEVLEEVKVTKEMKRKILLDVARTSLQTKVHAELADVLTEVVVDSVLAVR 180
           EGFEAAKIKALEVLEEVKVTKEMKRKILLDVARTSLQTKVHAELADVLTEVVVDSVLAVR
Sbjct: 121 EGFEAAKIKALEVLEEVKVTKEMKRKILLDVARTSLQTKVHAELADVLTEVVVDSVLAVR 180

Query: 181 RPGYPIDLFMVEIMEMKHKLGTDTKLIQGLVLDHGARHPDMKKRVEDAFILICNVSLEYE 240
           RPGYPIDLFMVEIMEMKHKLGTDTKLIQGLVLDHGARHPDMKKRVEDAFILICNVSLEYE
Sbjct: 181 RPGYPIDLFMVEIMEMKHKLGTDTKLIQGLVLDHGARHPDMKKRVEDAFILICNVSLEYE 240

Query: 241 KTEVNSGFFYKTAEEKEKLVKAERKFIEDRVQKIIDLKDKVCAQSNKGFVVINQKGIDPF 300
           KTEVNSGFFYKTAEEKEKLVKAERKFIEDRVQKIIDLKDKVCAQSNKGFVVINQKGIDPF
Sbjct: 241 KTEVNSGFFYKTAEEKEKLVKAERKFIEDRVQKIIDLKDKVCAQSNKGFVVINQKGIDPF 300

Query: 301 SLDSLAKHGIVALRRAKRRNMERLSLACGGMAVNSFEDLTVDCLGHAGLVYEYTLGEEKF 360
           SLDSLAKHGIVALRRAKRRNMERLSLACGGMAVNSFEDLTVDCLGHAGLVYEYTLGEEKF
Sbjct: 301 SLDSLAKHGIVALRRAKRRNMERLSLACGGMAVNSFEDLTVDCLGHAGLVYEYTLGEEKF 360

Query: 361 TFIEECVNPCSVTLLVKGPNKHTLTQVKDAIRDGLRAIKNAIEDGCMVPGAGAIEVAMAE 420
           TFIEECVNPCSVTLLVKGPNKHTLTQVKDAIRDGLRAIKNAIEDGCMVPGAGAIEVAMAE
Sbjct: 361 TFIEECVNPCSVTLLVKGPNKHTLTQVKDAIRDGLRAIKNAIEDGCMVPGAGAIEVAMAE 420

Query: 421 ALVTYKNSIKGRARLGVQAFADALLIIPKVLAQNAGYDPQETLVKVQAEHVESKQLVGVD 480
           ALVTYKNSIKGRARLGVQAFADALLIIPKVLAQNAGYDPQETLVKVQAEHVESKQLVGVD
Sbjct: 421 ALVTYKNSIKGRARLGVQAFADALLIIPKVLAQNAGYDPQETLVKVQAEHVESKQLVGVD 480

Query: 481 LNTGEPMVAADAGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLK 530
           LNTGEPMVAADAGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLK
Sbjct: 481 LNTGEPMVAADAGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLK 530


>gi|4502643 chaperonin containing TCP1, subunit 6A isoform a [Homo
           sapiens]
          Length = 531

 Score =  901 bits (2329), Expect = 0.0
 Identities = 455/530 (85%), Positives = 500/530 (94%)

Query: 1   MAAIKAVNSKAEVARARAALAVNICAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDG 60
           MAA+K +N KAEVARA+AALAVNI AARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDG
Sbjct: 1   MAAVKTLNPKAEVARAQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDG 60

Query: 61  NVLLDEMQIQHPTASLIAKVATAQDDVTGDGTTSNVLIIGELLKQADLYISEGLHPRIIA 120
           NVLL EMQIQHPTASLIAKVATAQDD+TGDGTTSNVLIIGELLKQADLYISEGLHPRII 
Sbjct: 61  NVLLHEMQIQHPTASLIAKVATAQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIIT 120

Query: 121 EGFEAAKIKALEVLEEVKVTKEMKRKILLDVARTSLQTKVHAELADVLTEVVVDSVLAVR 180
           EGFEAAK KAL+ LEEVKV++EM R+ L+DVARTSL+TKVHAELADVLTE VVDS+LA++
Sbjct: 121 EGFEAAKEKALQFLEEVKVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIK 180

Query: 181 RPGYPIDLFMVEIMEMKHKLGTDTKLIQGLVLDHGARHPDMKKRVEDAFILICNVSLEYE 240
           +   PIDLFM+EIMEMKHK  TDT LI+GLVLDHGARHPDMKKRVEDA+IL CNVSLEYE
Sbjct: 181 KQDEPIDLFMIEIMEMKHKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYE 240

Query: 241 KTEVNSGFFYKTAEEKEKLVKAERKFIEDRVQKIIDLKDKVCAQSNKGFVVINQKGIDPF 300
           KTEVNSGFFYK+AEE+EKLVKAERKFIEDRV+KII+LK KVC  S+KGFVVINQKGIDPF
Sbjct: 241 KTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPF 300

Query: 301 SLDSLAKHGIVALRRAKRRNMERLSLACGGMAVNSFEDLTVDCLGHAGLVYEYTLGEEKF 360
           SLD+L+K GIVALRRAKRRNMERL+LACGG+A+NSF+DL+ DCLGHAGLVYEYTLGEEKF
Sbjct: 301 SLDALSKEGIVALRRAKRRNMERLTLACGGVALNSFDDLSPDCLGHAGLVYEYTLGEEKF 360

Query: 361 TFIEECVNPCSVTLLVKGPNKHTLTQVKDAIRDGLRAIKNAIEDGCMVPGAGAIEVAMAE 420
           TFIE+C NP SVTLL+KGPNKHTLTQ+KDA+RDGLRA+KNAI+DGC+VPGAGA+EVAMAE
Sbjct: 361 TFIEKCNNPRSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAE 420

Query: 421 ALVTYKNSIKGRARLGVQAFADALLIIPKVLAQNAGYDPQETLVKVQAEHVESKQLVGVD 480
           AL+ +K S+KGRA+LGVQAFADALLIIPKVLAQN+G+D QETLVK+QAEH ES QLVGVD
Sbjct: 421 ALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHSESGQLVGVD 480

Query: 481 LNTGEPMVAADAGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLK 530
           LNTGEPMVAA+ GVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLK
Sbjct: 481 LNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLK 530


>gi|58331171 chaperonin containing TCP1, subunit 6A isoform b [Homo
           sapiens]
          Length = 486

 Score =  796 bits (2055), Expect = 0.0
 Identities = 411/530 (77%), Positives = 455/530 (85%), Gaps = 45/530 (8%)

Query: 1   MAAIKAVNSKAEVARARAALAVNICAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDG 60
           MAA+K +N KAEVARA+AALAVNI AARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDG
Sbjct: 1   MAAVKTLNPKAEVARAQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDG 60

Query: 61  NVLLDEMQIQHPTASLIAKVATAQDDVTGDGTTSNVLIIGELLKQADLYISEGLHPRIIA 120
           NVLL EM                                             GLHPRII 
Sbjct: 61  NVLLHEM---------------------------------------------GLHPRIIT 75

Query: 121 EGFEAAKIKALEVLEEVKVTKEMKRKILLDVARTSLQTKVHAELADVLTEVVVDSVLAVR 180
           EGFEAAK KAL+ LEEVKV++EM R+ L+DVARTSL+TKVHAELADVLTE VVDS+LA++
Sbjct: 76  EGFEAAKEKALQFLEEVKVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIK 135

Query: 181 RPGYPIDLFMVEIMEMKHKLGTDTKLIQGLVLDHGARHPDMKKRVEDAFILICNVSLEYE 240
           +   PIDLFM+EIMEMKHK  TDT LI+GLVLDHGARHPDMKKRVEDA+IL CNVSLEYE
Sbjct: 136 KQDEPIDLFMIEIMEMKHKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYE 195

Query: 241 KTEVNSGFFYKTAEEKEKLVKAERKFIEDRVQKIIDLKDKVCAQSNKGFVVINQKGIDPF 300
           KTEVNSGFFYK+AEE+EKLVKAERKFIEDRV+KII+LK KVC  S+KGFVVINQKGIDPF
Sbjct: 196 KTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPF 255

Query: 301 SLDSLAKHGIVALRRAKRRNMERLSLACGGMAVNSFEDLTVDCLGHAGLVYEYTLGEEKF 360
           SLD+L+K GIVALRRAKRRNMERL+LACGG+A+NSF+DL+ DCLGHAGLVYEYTLGEEKF
Sbjct: 256 SLDALSKEGIVALRRAKRRNMERLTLACGGVALNSFDDLSPDCLGHAGLVYEYTLGEEKF 315

Query: 361 TFIEECVNPCSVTLLVKGPNKHTLTQVKDAIRDGLRAIKNAIEDGCMVPGAGAIEVAMAE 420
           TFIE+C NP SVTLL+KGPNKHTLTQ+KDA+RDGLRA+KNAI+DGC+VPGAGA+EVAMAE
Sbjct: 316 TFIEKCNNPRSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAE 375

Query: 421 ALVTYKNSIKGRARLGVQAFADALLIIPKVLAQNAGYDPQETLVKVQAEHVESKQLVGVD 480
           AL+ +K S+KGRA+LGVQAFADALLIIPKVLAQN+G+D QETLVK+QAEH ES QLVGVD
Sbjct: 376 ALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHSESGQLVGVD 435

Query: 481 LNTGEPMVAADAGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLK 530
           LNTGEPMVAA+ GVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLK
Sbjct: 436 LNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLK 485


>gi|63162572 chaperonin containing TCP1, subunit 3 isoform a [Homo
           sapiens]
          Length = 545

 Score =  259 bits (662), Expect = 4e-69
 Identities = 154/523 (29%), Positives = 289/523 (55%), Gaps = 20/523 (3%)

Query: 8   NSKAEVARARAALAVNICAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLDEM 67
           N+K E    R   + NI AA+ + D++RT LGPK  MKML+   G I +T DGN +L E+
Sbjct: 13  NTKRE--SGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTNDGNAILREI 70

Query: 68  QIQHPTASLIAKVATAQDDVTGDGTTSNVLIIGELLKQADLYISEGLHPRIIAEGFEAAK 127
           Q+QHP A  + +++  QD+  GDGTTS +++ GE+L  A+ ++ + +HP ++   +  A 
Sbjct: 71  QVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPTVVISAYRKAL 130

Query: 128 IKALEVLEEVKVTKEMK-RKILLDVARTSLQTKVHAELADVLTEVVVDSVLAVR-----R 181
              +  L+++ +  ++    ++L++  +S+ TK  +  + +   + +D+V  V+     R
Sbjct: 131 DDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAVKMVQFEENGR 190

Query: 182 PGYPIDLFMVEIMEMKHKLGTDTKLIQGLVLDHGARHPDMKKRVEDAFILICNVSLEYEK 241
               I  +   + ++   +  D+ +++G++++    HP M++ +++  I++ + SLEY+K
Sbjct: 191 KEIDIKKY-ARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSSLEYKK 249

Query: 242 TEVNSGFFYKTAEEKEKLVKAERKFIEDRVQKIIDLKDKVCAQSNKGFVVINQKGIDPFS 301
            E  +       E+  ++++ E ++I+   + II LK           VVI +KGI   +
Sbjct: 250 GESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPD---------VVITEKGISDLA 300

Query: 302 LDSLAKHGIVALRRAKRRNMERLSLACGGMAVNSFEDLTVDCLG-HAGLVYEYTLGEEKF 360
              L +  I A+RR ++ +  R++ ACG   V+  E+L  D +G  AGL+    +G+E F
Sbjct: 301 QHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYF 360

Query: 361 TFIEECVNPCSVTLLVKGPNKHTLTQVKDAIRDGLRAIKNAIEDGCMVPGAGAIEVAMAE 420
           TFI +C +P + T+L++G +K  L++V+  ++D ++  +N + D  +VPG GA E+A+A 
Sbjct: 361 TFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAH 420

Query: 421 ALVTYKNSIKGRARLGVQAFADALLIIPKVLAQNAGYDPQETLVKVQAEHV-ESKQLVGV 479
           AL     ++ G  +   +A A AL +IP+ L QN G      L  ++A+H  E+ +  GV
Sbjct: 421 ALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGV 480

Query: 480 DLNTGEPMVAADAGVWDNYCVKKQLLHSCTVIATNILLVDEIM 522
           +  TG  +   + G+W+   VK Q   +    A  +L +D+I+
Sbjct: 481 NGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIV 523


>gi|58761486 chaperonin containing TCP1, subunit 3 isoform b [Homo
           sapiens]
          Length = 544

 Score =  258 bits (659), Expect = 9e-69
 Identities = 156/523 (29%), Positives = 290/523 (55%), Gaps = 21/523 (4%)

Query: 8   NSKAEVARARAALAVNICAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLDEM 67
           N+K E    R   + NI AA+ + D++RT LGPK  MKML+   G I +T DGN +L E+
Sbjct: 13  NTKRE--SGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTNDGNAILREI 70

Query: 68  QIQHPTASLIAKVATAQDDVTGDGTTSNVLIIGELLKQADLYISEGLHPRIIAEGFEAAK 127
           Q+QHP A  + +++  QD+  GDGTTS V+I+GE+L  A+ ++ + +HP ++   +  A 
Sbjct: 71  QVQHPAAKSMIEISRTQDEEVGDGTTS-VIILGEMLSVAEHFLEQQMHPTVVISAYRKAL 129

Query: 128 IKALEVLEEVKVTKEMKRK-ILLDVARTSLQTKVHAELADVLTEVVVDSVLAVR-----R 181
              +  L+++ +  ++    ++L++  +S+ TK  +  + +   + +D+V  V+     R
Sbjct: 130 DDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAVKMVQFEENGR 189

Query: 182 PGYPIDLFMVEIMEMKHKLGTDTKLIQGLVLDHGARHPDMKKRVEDAFILICNVSLEYEK 241
               I  +   + ++   +  D+ +++G++++    HP M++ +++  I++ + SLEY+K
Sbjct: 190 KEIDIKKY-ARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSSLEYKK 248

Query: 242 TEVNSGFFYKTAEEKEKLVKAERKFIEDRVQKIIDLKDKVCAQSNKGFVVINQKGIDPFS 301
            E  +       E+  ++++ E ++I+   + II LK  V         VI +KGI   +
Sbjct: 249 GESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDV---------VITEKGISDLA 299

Query: 302 LDSLAKHGIVALRRAKRRNMERLSLACGGMAVNSFEDLTVDCLGH-AGLVYEYTLGEEKF 360
              L +  I A+RR ++ +  R++ ACG   V+  E+L  D +G  AGL+    +G+E F
Sbjct: 300 QHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYF 359

Query: 361 TFIEECVNPCSVTLLVKGPNKHTLTQVKDAIRDGLRAIKNAIEDGCMVPGAGAIEVAMAE 420
           TFI +C +P + T+L++G +K  L++V+  ++D ++  +N + D  +VPG GA E+A+A 
Sbjct: 360 TFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAH 419

Query: 421 ALVTYKNSIKGRARLGVQAFADALLIIPKVLAQNAGYDPQETLVKVQAEHV-ESKQLVGV 479
           AL     ++ G  +   +A A AL +IP+ L QN G      L  ++A+H  E+ +  GV
Sbjct: 420 ALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGV 479

Query: 480 DLNTGEPMVAADAGVWDNYCVKKQLLHSCTVIATNILLVDEIM 522
           +  TG  +   + G+W+   VK Q   +    A  +L +D+I+
Sbjct: 480 NGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIV 522


>gi|24307939 chaperonin containing TCP1, subunit 5 (epsilon) [Homo
           sapiens]
          Length = 541

 Score =  251 bits (642), Expect = 9e-67
 Identities = 168/519 (32%), Positives = 280/519 (53%), Gaps = 22/519 (4%)

Query: 19  ALAVNICAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLDEMQIQHPTASLIA 78
           AL  +I AA+ + + +RT+LGP G  KM+V   GD+ +T DG  +L  M + H  A L+ 
Sbjct: 33  ALKSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTVTNDGATILSMMDVDHQIAKLMV 92

Query: 79  KVATAQDDVTGDGTTSNVLIIGELLKQADLYISEGLHPRIIAEGFEAAKIKALEVLEEV- 137
           +++ +QDD  GDGTT  V++ G LL++A+  +  G+HP  IA+G+E A   A+E L+++ 
Sbjct: 93  ELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRIADGYEQAARVAIEHLDKIS 152

Query: 138 -KVTKEMK-RKILLDVARTSLQTKVHAELADVLTEVVVDSVLAVR-RPGYPIDLFMVEIM 194
             V  ++K  + L+  A+T+L +KV       + E+ V++VL V       +D    E++
Sbjct: 153 DSVLVDIKDTEPLIQTAKTTLGSKVVNSCHRQMAEIAVNAVLTVADMERRDVDF---ELI 209

Query: 195 EMKHKLG---TDTKLIQGLVLDHGARHPDMKKRVEDAFILICNVSLEYEKTEVNSGFFYK 251
           +++ K+G    DTKLI+G+++D    HP M K+VEDA I I     E  K +        
Sbjct: 210 KVEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKPKTKHKLDVT 269

Query: 252 TAEEKEKLVKAERKFIEDRVQKIIDLKDKVCAQSNKGFVVINQKGIDPFSLDSLAKHGIV 311
           + E+ + L K E++  E+ +Q+I         +     + I Q G D  +   L ++ + 
Sbjct: 270 SVEDYKALQKYEKEKFEEMIQQI---------KETGANLAICQWGFDDEANHLLLQNNLP 320

Query: 312 ALRRAKRRNMERLSLACGGMAVNSFEDLTVDCLGHAGLVYEYTLG--EEKFTFIEECVNP 369
           A+R      +E +++A GG  V  F +LT + LG AGLV E + G  ++K   IE+C N 
Sbjct: 321 AVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGFAGLVQEISFGTTKDKMLVIEQCKNS 380

Query: 370 CSVTLLVKGPNKHTLTQVKDAIRDGLRAIKNAIEDGCMVPGAGAIEVAMAEALVTYKNSI 429
            +VT+ ++G NK  + + K ++ D L  I+N I D  +V G GA E++ A A+    +  
Sbjct: 381 RAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKC 440

Query: 430 KGRARLGVQAFADALLIIPKVLAQNAGYDPQETLVKVQAEHV-ESKQLVGVDLNTGEPMV 488
               +  ++AFADAL +IP  L++N+G +P +T+ +V+A  V E    +G+D        
Sbjct: 441 PTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQVKEMNPALGIDCLHKGTND 500

Query: 489 AADAGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMS 527
                V +    KKQ +   T +   IL +D+I + G S
Sbjct: 501 MKQQHVIETLIGKKQQISLATQMVRMILKIDDIRKPGES 539


>gi|57863257 T-complex protein 1 isoform a [Homo sapiens]
          Length = 556

 Score =  242 bits (618), Expect = 5e-64
 Identities = 150/523 (28%), Positives = 277/523 (52%), Gaps = 33/523 (6%)

Query: 23  NICAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLDEMQIQHPTASLIAKVAT 82
           N+ AA  + ++++++LGP G  KMLV   GD+ +T DG  +L  ++++HP A ++ ++A 
Sbjct: 21  NVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHPAAKVLCELAD 80

Query: 83  AQDDVTGDGTTSNVLIIGELLKQADLYISEGLHPRIIAEGFEAAKIKALEVLEE--VKVT 140
            QD   GDGTTS V+I  ELLK AD  + + +HP  +  G+  A  +A+  + E  +  T
Sbjct: 81  LQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVRYINENLIVNT 140

Query: 141 KEMKRKILLDVARTSLQTKVHAELADVLTEVVVDSVLAVR------RPGYPIDLFMVEIM 194
            E+ R  L++ A+TS+ +K+     D    +VVD+VLA++      +P YP++   V I+
Sbjct: 141 DELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIKYTDIRGQPRYPVN--SVNIL 198

Query: 195 EMKHKLGTDTKLIQGLVLDHGARHPDMKKRVEDAFILICNVSLEYEKTEVNSGFFYKTAE 254
           +   +   ++ LI G  L+       M KR+ +A I   + SL+  K ++         E
Sbjct: 199 KAHGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPE 258

Query: 255 EKEKLVKAERKFIEDRVQKIIDLKDKVCAQSNKGFVVINQKGIDPFSLDSLAKHGIVALR 314
           + +++ + E    ++R+QKI+         +    V++   GID   L    + G +A+R
Sbjct: 259 KLDQIRQRESDITKERIQKIL---------ATGANVILTTGGIDDMCLKYFVEAGAMAVR 309

Query: 315 RAKRRNMERLSLACGGMAVNSFEDLTVD------CLGHAGLVYEYTLGEEKFTFIEECVN 368
           R  +R+++R++ A G   +++  +L  +       LG A  V +  + +++   I+    
Sbjct: 310 RVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELILIKNTKA 369

Query: 369 PCSVTLLVKGPNKHTLTQVKDAIRDGLRAIKNAIEDGCMVPGAGAIEVAMAEALVTYKNS 428
             S +++++G N     +++ ++ D L  +K  +E   +VPG GA+E A++  L  Y  S
Sbjct: 370 RTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYLENYATS 429

Query: 429 IKGRARLGVQAFADALLIIPKVLAQNAGYDPQETLVKVQAEHVESK--------QLVGVD 480
           +  R +L +  FA +LL+IP  LA NA  D  + + K++A H E++        + +G+D
Sbjct: 430 MGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLD 489

Query: 481 LNTGEPMVAADAGVWDNYCVKKQLLHSCTVIATNILLVDEIMR 523
           L+ G+P     AGV++   VK + L   T  A  IL +D++++
Sbjct: 490 LSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIK 532


>gi|38455427 chaperonin containing TCP1, subunit 4 (delta) [Homo
           sapiens]
          Length = 539

 Score =  240 bits (612), Expect = 3e-63
 Identities = 160/510 (31%), Positives = 272/510 (53%), Gaps = 20/510 (3%)

Query: 23  NICAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLDEMQIQHPTASLIAKVAT 82
           NI AA+ + D +RT+LGPKG  KM+  G GD+ +T DG  +L +MQ+ HP A ++ +++ 
Sbjct: 37  NISAAKAVADAIRTSLGPKGMDKMIQDGKGDVTITNDGATILKQMQVLHPAARMLVELSK 96

Query: 83  AQDDVTGDGTTSNVLIIGELLKQADLYISEGLHPRIIAEGFEAAKIKALEVLEEVKVTKE 142
           AQD   GDGTTS V+I G LL      + +G+HP II+E F+ A  K +E+L ++    E
Sbjct: 97  AQDIEAGDGTTSVVIIAGSLLDSCTKLLQKGIHPTIISESFQKALEKGIEILTDMSRPVE 156

Query: 143 MK-RKILLDVARTSLQTKVHAELADVLTEVVVDSVLAVRRPGYPIDLFMVEIMEMKHKLG 201
           +  R+ LL+ A TSL +KV ++ + +L+ + V++V+ V  P     + + +I  +K   G
Sbjct: 157 LSDRETLLNSATTSLNSKVVSQYSSLLSPMSVNAVMKVIDPATATSVDLRDIKIVKKLGG 216

Query: 202 T--DTKLIQGLVLDHGARHPDMKKRVEDAFILICNVSLEYEKTEVNSGFFYKTAEEKEKL 259
           T  D +L++GLVL     +  +  RVE A I +    L   KT++++        + +++
Sbjct: 217 TIDDCELVEGLVLTQKVSNSGI-TRVEKAKIGLIQFCLSAPKTDMDNQIVVSDYAQMDRV 275

Query: 260 VKAERKFIEDRVQKIIDLKDKVCAQSNKGFVVINQKGIDPFSLDSLAKH-----GIVALR 314
           ++ ER +I + V++I   K   C       V++ QK I   +L  LA H      I+ ++
Sbjct: 276 LREERAYILNLVKQI---KKTGCN------VLLIQKSILRDALSDLALHFLNKMKIMVIK 326

Query: 315 RAKRRNMERLSLACGGMAVNSFEDLTVDCLGHAGLVYEYTL-GEEKFTFIEECVNP-CSV 372
             +R ++E +    G   V   +  T D LG A L  E  L G  K   I  C +P  +V
Sbjct: 327 DIEREDIEFICKTIGTKPVAHIDQFTADMLGSAELAEEVNLNGSGKLLKITGCASPGKTV 386

Query: 373 TLLVKGPNKHTLTQVKDAIRDGLRAIKNAIEDGCMVPGAGAIEVAMAEALVTYKNSIKGR 432
           T++V+G NK  + + + +I D L  I+  ++   ++ G GA E+ +A  L  Y  ++ G 
Sbjct: 387 TIVVRGSNKLVIEEAERSIHDALCVIRCLVKKRALIAGGGAPEIELALRLTEYSRTLSGM 446

Query: 433 ARLGVQAFADALLIIPKVLAQNAGYDPQETLVKVQAEHVESKQLVGVDLNTGEPMVAADA 492
               V+AFADA+ +IP  LA+NAG +P  T+ +++  H + ++  G+++  G      + 
Sbjct: 447 ESYCVRAFADAMEVIPSTLAENAGLNPISTVTELRNRHAQGEKTAGINVRKGGISNILEE 506

Query: 493 GVWDNYCVKKQLLHSCTVIATNILLVDEIM 522
            V     V    L   T    +IL +D+++
Sbjct: 507 LVVQPLLVSVSALTLATETVRSILKIDDVV 536


>gi|5453607 chaperonin containing TCP1, subunit 7 isoform a [Homo
           sapiens]
          Length = 543

 Score =  233 bits (593), Expect = 4e-61
 Identities = 150/521 (28%), Positives = 264/521 (50%), Gaps = 26/521 (4%)

Query: 20  LAVNICAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLDEMQIQHPTASLIAK 79
           L  NI A + + + +RT LGP+G  K++V G G   ++ DG  +L  + + HP A  +  
Sbjct: 22  LVSNISACQVIAEAVRTTLGPRGMDKLIVDGRGKATISNDGATILKLLDVVHPAAKTLVD 81

Query: 80  VATAQDDVTGDGTTSNVLIIGELLKQADLYISEGLHPRIIAEGFEAAKIKALEVLEEVKV 139
           +A +QD   GDGTTS  L+  E LKQ   Y+ EGLHP+II   F  A   A+  ++E+ V
Sbjct: 82  IAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEEGLHPQIIIRAFRTATQLAVNKIKEIAV 141

Query: 140 T-----KEMKRKILLDVARTSLQTKVHAELADVLTEVVVDSVLAVRRPGYPIDLFMVEIM 194
           T     K  +RK+L   A T+L +K+ ++      ++VVD+V+ +       DL  ++++
Sbjct: 142 TVKKADKVEQRKLLEKCAMTALSSKLISQQKAFFAKMVVDAVMMLD------DLLQLKMI 195

Query: 195 EMKHKLG---TDTKLIQGLVLDHGARHPDMK---KRVEDAFILICNVSLEYEKTEVNSGF 248
            +K   G    D++L+ G+       +   +   K+  +  I + NV LE +  + N+  
Sbjct: 196 GIKKVQGGALEDSQLVAGVAFKKTFSYAGFEMQPKKYHNPKIALLNVELELKAEKDNAEI 255

Query: 249 FYKTAEEKEKLVKAERKFIEDRVQKIIDLKDKVCAQSNKGFVVINQKGIDPFSLDSLAKH 308
              T E+ + +V AE   + D+++KI     KV         V+++  I   +    A  
Sbjct: 256 RVHTVEDYQAIVDAEWNILYDKLEKIHHSGAKV---------VLSKLPIGDVATQYFADR 306

Query: 309 GIVALRRAKRRNMERLSLACGGMAVNSFEDLTVDCLGHAGLVYEYTLGEEKFTFIEECVN 368
            +    R    +++R  +ACGG    S   L+ D LG   +  E  +G E++ F   C  
Sbjct: 307 DMFCAGRVPEEDLKRTMMACGGSIQTSVNALSADVLGRCQVFEETQIGGERYNFFTGCPK 366

Query: 369 PCSVTLLVKGPNKHTLTQVKDAIRDGLRAIKNAIEDGCMVPGAGAIEVAMAEALVTYKNS 428
             + T +++G  +  + + + ++ D +  ++ AI++  +V G GAIE+ +++ L  Y  +
Sbjct: 367 AKTCTFILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYLRDYSRT 426

Query: 429 IKGRARLGVQAFADALLIIPKVLAQNAGYDPQETLVKVQAEHVESKQLVGVDLNTGEPMV 488
           I G+ +L + A+A AL IIP+ L  NAG+D    L K++A H +     GVD+N  +   
Sbjct: 427 IPGKQQLLIGAYAKALEIIPRQLCDNAGFDATNILNKLRARHAQGGTWYGVDINNEDIAD 486

Query: 489 AADAGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSL 529
             +A VW+   V+   L + +  A  I+ VDE ++   S++
Sbjct: 487 NFEAFVWEPAMVRINALTAASEAACLIVSVDETIKNPRSTV 527


>gi|58761484 chaperonin containing TCP1, subunit 3 isoform c [Homo
           sapiens]
          Length = 507

 Score =  219 bits (558), Expect = 5e-57
 Identities = 129/473 (27%), Positives = 258/473 (54%), Gaps = 18/473 (3%)

Query: 58  KDGNVLLDEMQIQHPTASLIAKVATAQDDVTGDGTTSNVLIIGELLKQADLYISEGLHPR 117
           + GN+   ++Q+QHP A  + +++  QD+  GDGTTS +++ GE+L  A+ ++ + +HP 
Sbjct: 23  QSGNINAAKIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPT 82

Query: 118 IIAEGFEAAKIKALEVLEEVKVTKEMKRK-ILLDVARTSLQTKVHAELADVLTEVVVDSV 176
           ++   +  A    +  L+++ +  ++    ++L++  +S+ TK  +  + +   + +D+V
Sbjct: 83  VVISAYRKALDDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAV 142

Query: 177 LAVR-----RPGYPIDLFMVEIMEMKHKLGTDTKLIQGLVLDHGARHPDMKKRVEDAFIL 231
             V+     R    I  +   + ++   +  D+ +++G++++    HP M++ +++  I+
Sbjct: 143 KMVQFEENGRKEIDIKKY-ARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIV 201

Query: 232 ICNVSLEYEKTEVNSGFFYKTAEEKEKLVKAERKFIEDRVQKIIDLKDKVCAQSNKGFVV 291
           + + SLEY+K E  +       E+  ++++ E ++I+   + II LK  V         V
Sbjct: 202 LLDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDV---------V 252

Query: 292 INQKGIDPFSLDSLAKHGIVALRRAKRRNMERLSLACGGMAVNSFEDLTVDCLGH-AGLV 350
           I +KGI   +   L +  I A+RR ++ +  R++ ACG   V+  E+L  D +G  AGL+
Sbjct: 253 ITEKGISDLAQHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLL 312

Query: 351 YEYTLGEEKFTFIEECVNPCSVTLLVKGPNKHTLTQVKDAIRDGLRAIKNAIEDGCMVPG 410
               +G+E FTFI +C +P + T+L++G +K  L++V+  ++D ++  +N + D  +VPG
Sbjct: 313 EIKKIGDEYFTFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPG 372

Query: 411 AGAIEVAMAEALVTYKNSIKGRARLGVQAFADALLIIPKVLAQNAGYDPQETLVKVQAEH 470
            GA E+A+A AL     ++ G  +   +A A AL +IP+ L QN G      L  ++A+H
Sbjct: 373 GGASEMAVAHALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKH 432

Query: 471 V-ESKQLVGVDLNTGEPMVAADAGVWDNYCVKKQLLHSCTVIATNILLVDEIM 522
             E+ +  GV+  TG  +   + G+W+   VK Q   +    A  +L +D+I+
Sbjct: 433 TQENCETWGVNGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIV 485


>gi|5453603 chaperonin containing TCP1, subunit 2 [Homo sapiens]
          Length = 535

 Score =  217 bits (553), Expect = 2e-56
 Identities = 152/536 (28%), Positives = 278/536 (51%), Gaps = 30/536 (5%)

Query: 1   MAAIKAVNSKAEVARARAALAVNICAARGLQDVLRTNLGPKGTMKMLVSGAGDIKL--TK 58
           +A +    + A+  RA  A   +   A  + D++++ LGPKG  K+L+S   D  L  T 
Sbjct: 6   LAPVNIFKAGADEERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDASLMVTN 65

Query: 59  DGNVLLDEMQIQHPTASLIAKVATAQDDVTGDGTTSNVLIIGELLKQADLYISEGLHPRI 118
           DG  +L  + + +P A ++  ++  QDD  GDGTTS  ++  ELL++A+  I++ +HP+ 
Sbjct: 66  DGATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQT 125

Query: 119 IAEGFEAAKIKALEVLEEVKV---TKEMK-RKILLDVARTSLQTKVHAELADVLTEVVVD 174
           I  G+  A   A E L    V   + E+K R+ L+++A T+L +K+     D  T++ V+
Sbjct: 126 IIAGWREATKAAREALLSSAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFTKLAVE 185

Query: 175 SVLAVRRPGYPIDLFMVEIMEMKHKLG---TDTKLIQGLVLDH--GARHPDMKKRVEDAF 229
           +VL ++  G       +E + +  KLG    D+ L +G +LD   G   P   KR+E+A 
Sbjct: 186 AVLRLKGSGN------LEAIHIIKKLGGSLADSYLDEGFLLDKKIGVNQP---KRIENAK 236

Query: 230 ILICNVSLEYEKTEV-NSGFFYKTAEEKEKLVKAERKFIEDRVQKIIDLKDKVCAQSNKG 288
           ILI N  ++ +K ++  S     +  +  ++  AE++ ++++V++I  LK  +       
Sbjct: 237 ILIANTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERI--LKHGINC----- 289

Query: 289 FVVINQKGIDPFSLDSLAKHGIVALRRAKRRNMERLSLACGGMAVNSFEDLTVDCLGHAG 348
              IN++ I  +        G++A+  A    +ERL+L  GG   ++F+   +  LG   
Sbjct: 290 --FINRQLIYNYPEQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGSCK 347

Query: 349 LVYEYTLGEEKFTFIEECVNPCSVTLLVKGPNKHTLTQVKDAIRDGLRAIKNAIEDGCMV 408
           L+ E  +GE+K           + T++++G  +  L + + ++ D L  +   ++D   V
Sbjct: 348 LIEEVMIGEDKLIHFSGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDSRTV 407

Query: 409 PGAGAIEVAMAEALVTYKNSIKGRARLGVQAFADALLIIPKVLAQNAGYDPQETLVKVQA 468
            G G  E+ MA A+    N   G+  + ++++A AL ++P ++A NAGYD  + + +++A
Sbjct: 408 YGGGCSEMLMAHAVTQLANRTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQLRA 467

Query: 469 EHVESKQLVGVDLNTGEPMVAADAGVWDNYCVKKQLLHSCTVIATNILLVDEIMRA 524
            H E     G+D+  G     A  G+ +++ VK+Q+L S    A  IL VD I++A
Sbjct: 468 AHSEGNTTAGLDMREGTIGDMAILGITESFQVKRQVLLSAAEAAEVILRVDNIIKA 523


>gi|48762932 chaperonin containing TCP1, subunit 8 (theta) [Homo
           sapiens]
          Length = 548

 Score =  173 bits (438), Expect = 4e-43
 Identities = 127/508 (25%), Positives = 233/508 (45%), Gaps = 18/508 (3%)

Query: 23  NICAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLDEMQIQHPTASLIAKVAT 82
           NI A + L    RT  GP G  KM+++    + +T D   +L E+++QHP A +I   + 
Sbjct: 32  NIQACKELAQTTRTAYGPNGMNKMVINHLEKLFVTNDAATILRELEVQHPAAKMIVMASH 91

Query: 83  AQDDVTGDGTTSNVLIIGELLKQADLYISEGLHPRIIAEGFEAAKIKALEVLEEVKVTKE 142
            Q+   GDGT   ++  G LL+ A+  +  GL    + EG+E A  KA E+L  +     
Sbjct: 92  MQEQEVGDGTNFVLVFAGALLELAEELLRIGLSVSEVIEGYEIACRKAHEILPNLVCCSA 151

Query: 143 MKRKILLDVA---RTSLQTKVHAELADVLTEVVVDSVLAVRRPGYPIDLFMVEIMEMKHK 199
              + + +V+   RTS+ +K +      L +++  + +++       ++  + + ++   
Sbjct: 152 KNLRDIDEVSSLLRTSIMSKQYGNEV-FLAKLIAQACVSIFPDSGHFNVDNIRVCKILGS 210

Query: 200 LGTDTKLIQGLVLDHGARHPDMKKRVEDAFILICNVSLEYEKTEVNSGFFYKTAEEKEKL 259
             + + ++ G+V             V+DA I + +   +   TE       KTAEE    
Sbjct: 211 GISSSSVLHGMVFKKETEGDVTS--VKDAKIAVYSCPFDGMITETKGTVLIKTAEELMNF 268

Query: 260 VKAERKFIEDRVQKIIDLKDKVCAQSNKGFVVINQKGIDPFSLDSLAKHGIVALRRAKRR 319
            K E   ++ +V+ I D    V     K         +   +L    K+ I+ +R   + 
Sbjct: 269 SKGEENLMDAQVKAIADTGANVVVTGGK---------VADMALHYANKYNIMLVRLNSKW 319

Query: 320 NMERLSLACGGMAVNSFEDLTVDCLGHAGLVYEYTLGEEKFT-FIEECVNPCSVTLLVKG 378
           ++ RL    G  A+       ++ +GH   VY   +G+ +   F  E  +    T++++G
Sbjct: 320 DLRRLCKTVGATALPRLTPPVLEEMGHCDSVYLSEVGDTQVVVFKHEKEDGAISTIVLRG 379

Query: 379 PNKHTLTQVKDAIRDGLRAIKNAIEDGCMVPGAGAIEVAMAEALVTYKNSIKGRARLGVQ 438
              + +  ++ A+ DG+   K    D  +VPG GA E+ +A+ + +Y  +  G  +  ++
Sbjct: 380 STDNLMDDIERAVDDGVNTFKVLTRDKRLVPGGGATEIELAKQITSYGETCPGLEQYAIK 439

Query: 439 AFADALLIIPKVLAQNAGYDPQETLVKVQAEHVESKQLVGVDLNTGEPMV--AADAGVWD 496
            FA+A   IP+ LA+N+G    E + K+ A H E  + VG+D+    P V    +AG+ D
Sbjct: 440 KFAEAFEAIPRALAENSGVKANEVISKLYAVHQEGNKNVGLDIEAEVPAVKDMLEAGILD 499

Query: 497 NYCVKKQLLHSCTVIATNILLVDEIMRA 524
            Y  K   +   T  A  +L VD+I+ A
Sbjct: 500 TYLGKYWAIKLATNAAVTVLRVDQIIMA 527


>gi|57863259 T-complex protein 1 isoform b [Homo sapiens]
          Length = 401

 Score =  145 bits (366), Expect = 9e-35
 Identities = 100/388 (25%), Positives = 194/388 (50%), Gaps = 31/388 (7%)

Query: 156 LQTKVHAELADVLTEVVVDSVLAVR------RPGYPIDLFMVEIMEMKHKLGTDTKLIQG 209
           + +K+     D    +VVD+VLA++      +P YP++   V I++   +   ++ LI G
Sbjct: 1   MSSKIIGINGDFFANMVVDAVLAIKYTDIRGQPRYPVN--SVNILKAHGRSQMESMLISG 58

Query: 210 LVLDHGARHPDMKKRVEDAFILICNVSLEYEKTEVNSGFFYKTAEEKEKLVKAERKFIED 269
             L+       M KR+ +A I   + SL+  K ++         E+ +++ + E    ++
Sbjct: 59  YALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPEKLDQIRQRESDITKE 118

Query: 270 RVQKIIDLKDKVCAQSNKGFVVINQKGIDPFSLDSLAKHGIVALRRAKRRNMERLSLACG 329
           R+QKI+         +    V++   GID   L    + G +A+RR  +R+++R++ A G
Sbjct: 119 RIQKIL---------ATGANVILTTGGIDDMCLKYFVEAGAMAVRRVLKRDLKRIAKASG 169

Query: 330 GMAVNSFEDLTVD------CLGHAGLVYEYTLGEEKFTFIEECVNPCSVTLLVKGPNKHT 383
              +++  +L  +       LG A  V +  + +++   I+      S +++++G N   
Sbjct: 170 ATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELILIKNTKARTSASIILRGANDFM 229

Query: 384 LTQVKDAIRDGLRAIKNAIEDGCMVPGAGAIEVAMAEALVTYKNSIKGRARLGVQAFADA 443
             +++ ++ D L  +K  +E   +VPG GA+E A++  L  Y  S+  R +L +  FA +
Sbjct: 230 CDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARS 289

Query: 444 LLIIPKVLAQNAGYDPQETLVKVQAEHVESK--------QLVGVDLNTGEPMVAADAGVW 495
           LL+IP  LA NA  D  + + K++A H E++        + +G+DL+ G+P     AGV+
Sbjct: 290 LLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLSNGKPRDNKQAGVF 349

Query: 496 DNYCVKKQLLHSCTVIATNILLVDEIMR 523
           +   VK + L   T  A  IL +D++++
Sbjct: 350 EPTIVKVKSLKFATEAAITILRIDDLIK 377


>gi|58331185 chaperonin containing TCP1, subunit 7 isoform b [Homo
           sapiens]
          Length = 339

 Score =  132 bits (331), Expect = 1e-30
 Identities = 86/330 (26%), Positives = 161/330 (48%), Gaps = 12/330 (3%)

Query: 203 DTKLIQGLVLDHGARHPDMK---KRVEDAFILICNVSLEYEKTEVNSGFFYKTAEEKEKL 259
           D++L+ G+       +   +   K+  +  I + NV LE +  + N+     T E+ + +
Sbjct: 3   DSQLVAGVAFKKTFSYAGFEMQPKKYHNPKIALLNVELELKAEKDNAEIRVHTVEDYQAI 62

Query: 260 VKAERKFIEDRVQKIIDLKDKVCAQSNKGFVVINQKGIDPFSLDSLAKHGIVALRRAKRR 319
           V AE   + D+++KI     KV         V+++  I   +    A   +    R    
Sbjct: 63  VDAEWNILYDKLEKIHHSGAKV---------VLSKLPIGDVATQYFADRDMFCAGRVPEE 113

Query: 320 NMERLSLACGGMAVNSFEDLTVDCLGHAGLVYEYTLGEEKFTFIEECVNPCSVTLLVKGP 379
           +++R  +ACGG    S   L+ D LG   +  E  +G E++ F   C    + T +++G 
Sbjct: 114 DLKRTMMACGGSIQTSVNALSADVLGRCQVFEETQIGGERYNFFTGCPKAKTCTFILRGG 173

Query: 380 NKHTLTQVKDAIRDGLRAIKNAIEDGCMVPGAGAIEVAMAEALVTYKNSIKGRARLGVQA 439
            +  + + + ++ D +  ++ AI++  +V G GAIE+ +++ L  Y  +I G+ +L + A
Sbjct: 174 AEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYLRDYSRTIPGKQQLLIGA 233

Query: 440 FADALLIIPKVLAQNAGYDPQETLVKVQAEHVESKQLVGVDLNTGEPMVAADAGVWDNYC 499
           +A AL IIP+ L  NAG+D    L K++A H +     GVD+N  +     +A VW+   
Sbjct: 234 YAKALEIIPRQLCDNAGFDATNILNKLRARHAQGGTWYGVDINNEDIADNFEAFVWEPAM 293

Query: 500 VKKQLLHSCTVIATNILLVDEIMRAGMSSL 529
           V+   L + +  A  I+ VDE ++   S++
Sbjct: 294 VRINALTAASEAACLIVSVDETIKNPRSTV 323


>gi|7657253 T-complex protein 1 [Homo sapiens]
          Length = 557

 Score =  119 bits (297), Expect = 9e-27
 Identities = 120/509 (23%), Positives = 213/509 (41%), Gaps = 16/509 (3%)

Query: 20  LAVNICAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLDEMQIQHPTASLIAK 79
           L  ++ A + L  V+R   GP G  K LV+  G+   T     +L  ++++HP A L+ +
Sbjct: 33  LLSSLAAVQTLASVIRPCYGPHGRQKFLVTMKGETVCTGCATAILRALELEHPAAWLLRE 92

Query: 80  VATAQDDVTGDGTTSNVLIIGELLKQADLYISEGLHPRIIAEGFEAAKIKALEVLEEVKV 139
               Q + +GDGT   VL+   LL+QA+  +  GL    + E +  A  + L  L  + +
Sbjct: 93  AGQTQAENSGDGTAFVVLLTEALLEQAEQLLKAGLPRPQLREAYATATAEVLATLPSLAI 152

Query: 140 TKEMKRKILLDVARTSLQTKVHAELADVLTEVVVDSVLAVRRPGYPIDLFMVEIMEMKHK 199
                 +       + + T   + + D LT++V  +  A++          V +  +   
Sbjct: 153 QSLGPLEDPSWALHSVMNTHTLSPM-DHLTKLVAHACWAIKELDGSFKPERVGVCALPGG 211

Query: 200 LGTDTKLIQGLVLDHGARHPDMKKRVEDAFILICNVSLEYEKTEVNSGFFYKTAEEKEKL 259
              D+ L+ GL +  G     M   +  A + +             +     +  +  + 
Sbjct: 212 TLEDSCLLPGLAIS-GKLCGQMATVLSGARVALFACPFGPAHPNAPATARLSSPADLAQF 270

Query: 260 VKAERKFIEDRVQKIIDLKDKVCAQSNKGFVVINQKGIDPFSLDSLAKHGIVALRRAKRR 319
            K   + +E +V ++      V        VV+ +  +D  +L    K+GIV ++     
Sbjct: 271 SKGSDQLLEKQVGQLAAAGINVA-------VVLGE--VDEETLTLADKYGIVVIQARSWM 321

Query: 320 NMERLSLACGGMAVNSFEDLTVDCLGHAGLVYEYTLGEEKFTFIE-ECVNPCSVTLLVKG 378
            +  LS       +     L     G    VY   LG+      E EC    ++T++++G
Sbjct: 322 EIIYLSEVLDTPLLPRL--LPPQRPGKCQRVYRQELGDGLAVVFEWECTGTPALTVVLRG 379

Query: 379 PNKHTLTQVKDAIRDGLRAIKNAIEDGCMVPGAGAIEVAMAEALVTYKNSIKGRARLGVQ 438
                L   + A+  G+ A     +D  ++PGAGA E+A+A+ L    + ++G +     
Sbjct: 380 ATTQGLRSAEQAVYHGIDAYFQLCQDPRLIPGAGATEMALAKMLSDKGSRLEGPSGPAFL 439

Query: 439 AFADALLIIPKVLAQNAGYDPQETLVKVQAEHVESKQLVGVDLNTGEPMVAADAGVWDNY 498
           AFA AL  +PK LA+NAG    + + ++   H     L+GV   T   +  A  GVWD  
Sbjct: 440 AFAWALKYLPKTLAENAGLAVSDVMAEMSGVHQGGNLLMGV--GTEGIINVAQEGVWDTL 497

Query: 499 CVKKQLLHSCTVIATNILLVDEIMRAGMS 527
            VK Q   +   +   ++ VDEI+ A  S
Sbjct: 498 IVKAQGFRAVAEVVLQLVTVDEIVVAKKS 526


>gi|41399285 chaperonin [Homo sapiens]
          Length = 573

 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 101/526 (19%), Positives = 210/526 (39%), Gaps = 59/526 (11%)

Query: 30  LQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLDEMQIQHPT----ASLIAKVATAQD 85
           L D +   +GPKG   ++    G  K+TKDG  +   + ++       A L+  VA   +
Sbjct: 47  LADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTN 106

Query: 86  DVTGDGTTSNVLIIGELLKQADLYISEGLHPRIIAEGFEAAKIKALEVLEEVKVTKEMKR 145
           +  GDGTT+  ++   + K+    IS+G +P  I  G   A       ++ V    + + 
Sbjct: 107 EEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLA-------VDAVIAELKKQS 159

Query: 146 KILLDVARTSLQTKVHAELADVLTEVVVDSVLAVRRPGYPIDLFMVEIMEMKHKLGTDTK 205
           K +      +    + A     +  ++ D++  V R G      ++ + + K  L  + +
Sbjct: 160 KPVTTPEEIAQVATISANGDKEIGNIISDAMKKVGRKG------VITVKDGK-TLNDELE 212

Query: 206 LIQGLVLDHGARHP-------DMKKRVEDAFILICNVSLEYEKTEVNSGFFYKTAEEKEK 258
           +I+G+  D G   P         K   +DA++L+    +   ++ V        A  K  
Sbjct: 213 IIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSIQSIV-PALEIANAHRKPL 271

Query: 259 LVKAE-------RKFIEDRVQ---KIIDLKDKVCAQSNK----------GFVVINQKGID 298
           ++ AE          + +R++   +++ +K      + K          G  V  ++G+ 
Sbjct: 272 VIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGL- 330

Query: 299 PFSLDSLAKHGIVALRRAKRRNMERLSLACGG--MAVNSFEDLTVDCLGHAGLVYEYTLG 356
             +L+ +  H +  +        + + L   G    +       ++ L      YE    
Sbjct: 331 TLNLEDVQPHDLGKVGEVIVTKDDAMLLKGKGDKAQIEKRIQEIIEQLDVTTSEYEKEKL 390

Query: 357 EEKFTFIEECVNPCSVTLLVKGPNKHTLTQVKDAIRDGLRAIKNAIEDGCMVPGAGAIEV 416
            E+   + + V      L V G +   + + KD + D L A + A+E+G +V G G   +
Sbjct: 391 NERLAKLSDGV----AVLKVGGTSDVEVNEKKDRVTDALNATRAAVEEG-IVLGGGCALL 445

Query: 417 AMAEALVTYKNSIKGRARLGVQAFADALLIIPKVLAQNAGYDPQETLVKVQAEHVESKQL 476
               AL +   + + + ++G++     L I    +A+NAG +    + K+    ++S   
Sbjct: 446 RCIPALDSLTPANEDQ-KIGIEIIKRTLKIPAMTIAKNAGVEGSLIVEKI----MQSSSE 500

Query: 477 VGVDLNTGEPMVAADAGVWDNYCVKKQLLHSCTVIATNILLVDEIM 522
           VG D   G+ +   + G+ D   V +  L     +A+ +   + ++
Sbjct: 501 VGYDAMAGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEVVV 546


>gi|31542947 chaperonin [Homo sapiens]
          Length = 573

 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 101/526 (19%), Positives = 210/526 (39%), Gaps = 59/526 (11%)

Query: 30  LQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLDEMQIQHPT----ASLIAKVATAQD 85
           L D +   +GPKG   ++    G  K+TKDG  +   + ++       A L+  VA   +
Sbjct: 47  LADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTN 106

Query: 86  DVTGDGTTSNVLIIGELLKQADLYISEGLHPRIIAEGFEAAKIKALEVLEEVKVTKEMKR 145
           +  GDGTT+  ++   + K+    IS+G +P  I  G   A       ++ V    + + 
Sbjct: 107 EEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLA-------VDAVIAELKKQS 159

Query: 146 KILLDVARTSLQTKVHAELADVLTEVVVDSVLAVRRPGYPIDLFMVEIMEMKHKLGTDTK 205
           K +      +    + A     +  ++ D++  V R G      ++ + + K  L  + +
Sbjct: 160 KPVTTPEEIAQVATISANGDKEIGNIISDAMKKVGRKG------VITVKDGK-TLNDELE 212

Query: 206 LIQGLVLDHGARHP-------DMKKRVEDAFILICNVSLEYEKTEVNSGFFYKTAEEKEK 258
           +I+G+  D G   P         K   +DA++L+    +   ++ V        A  K  
Sbjct: 213 IIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSIQSIV-PALEIANAHRKPL 271

Query: 259 LVKAE-------RKFIEDRVQ---KIIDLKDKVCAQSNK----------GFVVINQKGID 298
           ++ AE          + +R++   +++ +K      + K          G  V  ++G+ 
Sbjct: 272 VIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGL- 330

Query: 299 PFSLDSLAKHGIVALRRAKRRNMERLSLACGG--MAVNSFEDLTVDCLGHAGLVYEYTLG 356
             +L+ +  H +  +        + + L   G    +       ++ L      YE    
Sbjct: 331 TLNLEDVQPHDLGKVGEVIVTKDDAMLLKGKGDKAQIEKRIQEIIEQLDVTTSEYEKEKL 390

Query: 357 EEKFTFIEECVNPCSVTLLVKGPNKHTLTQVKDAIRDGLRAIKNAIEDGCMVPGAGAIEV 416
            E+   + + V      L V G +   + + KD + D L A + A+E+G +V G G   +
Sbjct: 391 NERLAKLSDGV----AVLKVGGTSDVEVNEKKDRVTDALNATRAAVEEG-IVLGGGCALL 445

Query: 417 AMAEALVTYKNSIKGRARLGVQAFADALLIIPKVLAQNAGYDPQETLVKVQAEHVESKQL 476
               AL +   + + + ++G++     L I    +A+NAG +    + K+    ++S   
Sbjct: 446 RCIPALDSLTPANEDQ-KIGIEIIKRTLKIPAMTIAKNAGVEGSLIVEKI----MQSSSE 500

Query: 477 VGVDLNTGEPMVAADAGVWDNYCVKKQLLHSCTVIATNILLVDEIM 522
           VG D   G+ +   + G+ D   V +  L     +A+ +   + ++
Sbjct: 501 VGYDAMAGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEVVV 546


>gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III
           isoform 2 [Homo sapiens]
          Length = 2098

 Score = 59.3 bits (142), Expect = 8e-09
 Identities = 74/321 (23%), Positives = 137/321 (42%), Gaps = 47/321 (14%)

Query: 100 GELLKQADLYISEGLHPRIIAEGFEAAKIKAL-------EVLEEVKVTKEMKRKILL--- 149
           G+ L  +D +I E L  R + E  +      L       E+L E    K+   ++L    
Sbjct: 554 GQQLSISDAFIKESLFNRRVEEKSKELPFTPLGWHHNNLELLREENGEKQAMERLLSANH 613

Query: 150 DVARTSLQTKVHAELA-----DVLTEVVVDSVLAVRRP--GYPIDLFMVEIMEMKHKLGT 202
           +     LQ  +H++       D++  +V   V  VR        D+ + + + +K   G 
Sbjct: 614 NHMMALLQQLLHSDSLSSSWRDIIVSLVCQVVQTVRPDVKNQDDDMDIRQFVHIKKIPGG 673

Query: 203 ---DTKLIQGLVLDHGARHPDMKKRVEDAFILICNVSLEY---EKTEVNSGFFYKTAEEK 256
              D+ ++ G V      H  M   +++  IL+   S+EY   E+T+             
Sbjct: 674 KKFDSVVVNGFVCTKNIAHKKMSSCIKNPKILLLKCSIEYLYREETKFTC---------I 724

Query: 257 EKLVKAERKFIEDRVQKIIDLKDKVCAQSNKGFVVINQKGIDPFSLDSLAKHGIVALRRA 316
           + +V  ER+F+++ VQ+I+D++  +         V+ +K +   + D L +HGI  +   
Sbjct: 725 DPIVLQEREFLKNYVQRIVDVRPTL---------VLVEKTVSRIAQDMLLEHGITLVINV 775

Query: 317 KRRNMERLSLACGGMAVNSFED-LTVDCLG--HAGLVYEYTLGEEK---FTFIEECVNPC 370
           K + +ER+S    G  V S +  LT   LG  H   +  + L  E+     F E C    
Sbjct: 776 KSQVLERISRMTQGDLVMSMDQLLTKPHLGTCHKFYMQIFQLPNEQTKTLMFFEGCPQHL 835

Query: 371 SVTLLVKGPNKHTLTQVKDAI 391
             T+ ++G + + L +VK+ +
Sbjct: 836 GCTIKLRGGSDYELARVKEIL 856


>gi|100816407 Bardet-Biedl syndrome 10 [Homo sapiens]
          Length = 723

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 26/98 (26%), Positives = 52/98 (53%), Gaps = 4/98 (4%)

Query: 7   VNSKAEVARARAALAVNICAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLDE 66
           ++S A     +AAL V    A  L+ ++   +GP+G   +     G++ L+++G  LL+ 
Sbjct: 2   LSSMAAAGSVKAALQV----AEVLEAIVSCCVGPEGRQVLCTKPTGEVLLSRNGGRLLEA 57

Query: 67  MQIQHPTASLIAKVATAQDDVTGDGTTSNVLIIGELLK 104
           + ++HP A +I    ++    TGDG  + ++ +  LL+
Sbjct: 58  LHLEHPIARMIVDCVSSHLKKTGDGAKTFIIFLCHLLR 95


>gi|7705682 geminin [Homo sapiens]
          Length = 209

 Score = 31.6 bits (70), Expect = 1.9
 Identities = 38/161 (23%), Positives = 72/161 (44%), Gaps = 7/161 (4%)

Query: 30  LQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLDEMQIQHPTASLIAKVATAQDDVTG 89
           +++ ++ +  P+ T+KM+   A    + ++  +     + +H    L +   T+   V  
Sbjct: 12  IKENIKNSSVPRRTLKMIQPSASGSLVGRENELSAGLSKRKHRNDHLTS--TTSSPGVIV 69

Query: 90  DGTTSNVLIIGELLKQADLYISEGLHPRIIAEGFEAAKIKALEVLEE-VKVTKEMKRKIL 148
             ++ N  + G   +  DL I E    +   E  E  +    E L+E  K+ KE+++K  
Sbjct: 70  PESSENKNLGGVTQESFDLMIKENPSSQYWKEVAEKRRKALYEALKENEKLHKEIEQKDN 129

Query: 149 LDVARTSLQTKVHAELADVLTEVVVDSVLAVRRPGYPIDLF 189
            ++AR   + K   ELA+V   V   + L  R  G P+D F
Sbjct: 130 -EIARLKKENK---ELAEVAEHVQYMAELIERLNGEPLDNF 166


>gi|115298659 spectrin, alpha, erythrocytic 1 [Homo sapiens]
          Length = 2419

 Score = 30.0 bits (66), Expect = 5.5
 Identities = 21/76 (27%), Positives = 39/76 (51%), Gaps = 1/76 (1%)

Query: 213  DHGARHPDMKKRVEDAFILICNVSLEYEKTEVNSGFFYKTAEEKEKLVKAERKFIEDRVQ 272
            D+  +  + K  V +A+I     SL+      + G F     +++ L  + + F ++R+ 
Sbjct: 1927 DYAFQEFNWKADVVEAWIADKETSLKTNGNGADLGDFLTLLAKQDTLDASLQSFQQERLP 1986

Query: 273  KIIDLKDK-VCAQSNK 287
            +I DLKDK + AQ N+
Sbjct: 1987 EITDLKDKLISAQHNQ 2002


>gi|28329436 aprataxin isoform a [Homo sapiens]
          Length = 342

 Score = 29.6 bits (65), Expect = 7.1
 Identities = 11/23 (47%), Positives = 18/23 (78%)

Query: 283 AQSNKGFVVINQKGIDPFSLDSL 305
           A+ NKG+V + Q G++P S+DS+
Sbjct: 49  AECNKGYVKVKQVGVNPTSIDSV 71


>gi|28329430 aprataxin isoform b [Homo sapiens]
          Length = 306

 Score = 29.6 bits (65), Expect = 7.1
 Identities = 11/23 (47%), Positives = 18/23 (78%)

Query: 283 AQSNKGFVVINQKGIDPFSLDSL 305
           A+ NKG+V + Q G++P S+DS+
Sbjct: 63  AECNKGYVKVKQVGVNPTSIDSV 85


>gi|52630447 palmitoylated membrane protein 2 [Homo sapiens]
          Length = 552

 Score = 29.6 bits (65), Expect = 7.1
 Identities = 21/55 (38%), Positives = 30/55 (54%), Gaps = 6/55 (10%)

Query: 129 KALEVLEEVKVTK------EMKRKILLDVARTSLQTKVHAELADVLTEVVVDSVL 177
           KA E LEE K+        E+ ++IL D+A  + Q+   AELA +L E    S+L
Sbjct: 50  KAHERLEETKLEAVRDNNLELVQEILRDLAHVAEQSSTAAELAHILQEPHFQSLL 104


>gi|21450705 leucine rich repeat containing 45 [Homo sapiens]
          Length = 670

 Score = 29.3 bits (64), Expect = 9.3
 Identities = 20/84 (23%), Positives = 46/84 (54%), Gaps = 7/84 (8%)

Query: 203 DTKLIQGLVLDHGARHPD-----MKKRVEDAFILICNVSLEYEKTEVNSGFFYKTAEEKE 257
           D++ ++   ++H  RH +     M++RV+   +    +SLE E + V +    +  + +E
Sbjct: 428 DSESLRIKEVEHMTRHLEESEKAMQERVQR--LEAARLSLEEELSRVKAAALSERGQAEE 485

Query: 258 KLVKAERKFIEDRVQKIIDLKDKV 281
           +L+KA+ +   +  Q++  L+DK+
Sbjct: 486 ELIKAKSQARLEEQQRLAHLEDKL 509


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.374 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,866,688
Number of Sequences: 37866
Number of extensions: 677829
Number of successful extensions: 1780
Number of sequences better than 10.0: 25
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1717
Number of HSP's gapped (non-prelim): 27
length of query: 530
length of database: 18,247,518
effective HSP length: 107
effective length of query: 423
effective length of database: 14,195,856
effective search space: 6004847088
effective search space used: 6004847088
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.