Guide to the Human Genome
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Search of human proteins with 5802982

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5802982 proline-rich nuclear receptor coactivator 1 [Homo
sapiens]
         (327 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5802982 proline-rich nuclear receptor coactivator 1 [Homo sap...   664   0.0  
gi|169161132 PREDICTED: hypothetical protein LOC100131261 [Homo ...    89   4e-18
gi|169160897 PREDICTED: similar to hCG1728885 [Homo sapiens]           87   2e-17
gi|169162148 PREDICTED: similar to hCG1728885 [Homo sapiens]           87   2e-17
gi|8923295 proline-rich nuclear receptor coactivator 2 [Homo sap...    86   6e-17
gi|188536004 zinc finger protein 469 [Homo sapiens]                    49   6e-06
gi|92859678 small nuclear RNA activating complex, polypeptide 4,...    48   1e-05
gi|171543895 ataxin 2 [Homo sapiens]                                   46   4e-05
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    45   9e-05
gi|163965366 nascent polypeptide-associated complex alpha subuni...    45   9e-05
gi|16950645 neurotrophic factor artemin isoform 2 [Homo sapiens]       45   1e-04
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    44   2e-04
gi|9945318 MAX binding protein [Homo sapiens]                          44   2e-04
gi|42475970 synapse defective 1, Rho GTPase, homolog 1 [Homo sap...    44   2e-04
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    44   2e-04
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    44   2e-04
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    43   3e-04
gi|239743660 PREDICTED: hypothetical protein XP_002342926 [Homo ...    43   4e-04
gi|14602439 Williams Beuren syndrome chromosome region 14 isofor...    42   6e-04
gi|14602437 Williams Beuren syndrome chromosome region 14 isofor...    42   6e-04
gi|14602435 Williams Beuren syndrome chromosome region 14 isofor...    42   6e-04
gi|14602433 Williams Beuren syndrome chromosome region 14 isofor...    42   6e-04
gi|194733742 Wolf-Hirschhorn syndrome candidate 2 protein [Homo ...    42   6e-04
gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens]    42   6e-04
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    42   7e-04
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    42   7e-04
gi|116256363 transmembrane protease, serine 13 [Homo sapiens]          42   7e-04
gi|145309322 insulinoma-associated protein IA-6 [Homo sapiens]         42   0.001
gi|148237270 hypermethylated in cancer 1 isoform 2 [Homo sapiens]      42   0.001
gi|61676186 hypermethylated in cancer 1 isoform 1 [Homo sapiens]       42   0.001

>gi|5802982 proline-rich nuclear receptor coactivator 1 [Homo
           sapiens]
          Length = 327

 Score =  664 bits (1713), Expect = 0.0
 Identities = 327/327 (100%), Positives = 327/327 (100%)

Query: 1   MTVVSVPQREPLVLGGRLAPLGFSSRGYFGALPMVTTAPPPLPRIPDPRALPPTLFLPHF 60
           MTVVSVPQREPLVLGGRLAPLGFSSRGYFGALPMVTTAPPPLPRIPDPRALPPTLFLPHF
Sbjct: 1   MTVVSVPQREPLVLGGRLAPLGFSSRGYFGALPMVTTAPPPLPRIPDPRALPPTLFLPHF 60

Query: 61  LGGDGPCLTPQPRAPAALPNRSLAVAGGTPRAAPKKRRKKKVRASPAGQLPSRFHQYQQH 120
           LGGDGPCLTPQPRAPAALPNRSLAVAGGTPRAAPKKRRKKKVRASPAGQLPSRFHQYQQH
Sbjct: 61  LGGDGPCLTPQPRAPAALPNRSLAVAGGTPRAAPKKRRKKKVRASPAGQLPSRFHQYQQH 120

Query: 121 RPSLEGGRSPATGPSGAQEVPGPAAALAPSPAAAAGTEGASPDLAPLRPAAPGQTPLRKE 180
           RPSLEGGRSPATGPSGAQEVPGPAAALAPSPAAAAGTEGASPDLAPLRPAAPGQTPLRKE
Sbjct: 121 RPSLEGGRSPATGPSGAQEVPGPAAALAPSPAAAAGTEGASPDLAPLRPAAPGQTPLRKE 180

Query: 181 VLKSKMGKSEKIALPHGQLVHGIHLYEQPKINRQKSKYNLPLTKITSAKRNENNFWQDSV 240
           VLKSKMGKSEKIALPHGQLVHGIHLYEQPKINRQKSKYNLPLTKITSAKRNENNFWQDSV
Sbjct: 181 VLKSKMGKSEKIALPHGQLVHGIHLYEQPKINRQKSKYNLPLTKITSAKRNENNFWQDSV 240

Query: 241 SSDRIQKQEKKPFKNTENIKNSHLKKSAFLTEVSQKENYAGAKFSDPPSPSVLPKPPSHW 300
           SSDRIQKQEKKPFKNTENIKNSHLKKSAFLTEVSQKENYAGAKFSDPPSPSVLPKPPSHW
Sbjct: 241 SSDRIQKQEKKPFKNTENIKNSHLKKSAFLTEVSQKENYAGAKFSDPPSPSVLPKPPSHW 300

Query: 301 MGSTVENSNQNRELMAVHLKTLLKVQT 327
           MGSTVENSNQNRELMAVHLKTLLKVQT
Sbjct: 301 MGSTVENSNQNRELMAVHLKTLLKVQT 327


>gi|169161132 PREDICTED: hypothetical protein LOC100131261 [Homo
           sapiens]
          Length = 139

 Score = 89.4 bits (220), Expect = 4e-18
 Identities = 52/121 (42%), Positives = 72/121 (59%), Gaps = 5/121 (4%)

Query: 208 QPKINRQKSKYNLPLTKITSAKRNENNFWQDSVSSDRIQKQ--EKKPFKNTENIKNSHLK 265
           Q ++NRQK+K      KI   K+   + +  S  + +  K   + K F N ++  NS L 
Sbjct: 21  QQQLNRQKTKEQNSQMKIVHKKKERGHGYNSSAGAWQAMKNGGKNKNFPNNQSW-NSSLS 79

Query: 266 KSAFLTEVSQKENYAGAKFSDPPSPSVLPKPPSHWMGSTVENSNQNRELMAVHLKTLLKV 325
             + L +   K+NYAGAKFS+PPSPSVLPKPPSHW+   V  +  ++E+M   LKTLLKV
Sbjct: 80  GPSLLFKSQAKQNYAGAKFSEPPSPSVLPKPPSHWV--PVSFNPSDKEIMTFQLKTLLKV 137

Query: 326 Q 326
           Q
Sbjct: 138 Q 138


>gi|169160897 PREDICTED: similar to hCG1728885 [Homo sapiens]
          Length = 139

 Score = 87.4 bits (215), Expect = 2e-17
 Identities = 51/121 (42%), Positives = 71/121 (58%), Gaps = 5/121 (4%)

Query: 208 QPKINRQKSKYNLPLTKITSAKRNENNFWQDSVSSDRIQKQ--EKKPFKNTENIKNSHLK 265
           Q ++NRQK+K      KI   K+   + +  S  + +  K   + K F N ++  NS L 
Sbjct: 21  QQQLNRQKTKEQNSQMKIVHKKKERGHGYNSSAGAWQAMKNGGKNKNFPNNQSW-NSSLS 79

Query: 266 KSAFLTEVSQKENYAGAKFSDPPSPSVLPKPPSHWMGSTVENSNQNRELMAVHLKTLLKV 325
             + L +    +NYAGAKFS+PPSPSVLPKPPSHW+   V  +  ++E+M   LKTLLKV
Sbjct: 80  GPSLLFKSQANQNYAGAKFSEPPSPSVLPKPPSHWV--PVSFNPSDKEIMTFQLKTLLKV 137

Query: 326 Q 326
           Q
Sbjct: 138 Q 138


>gi|169162148 PREDICTED: similar to hCG1728885 [Homo sapiens]
          Length = 139

 Score = 87.4 bits (215), Expect = 2e-17
 Identities = 51/121 (42%), Positives = 71/121 (58%), Gaps = 5/121 (4%)

Query: 208 QPKINRQKSKYNLPLTKITSAKRNENNFWQDSVSSDRIQKQ--EKKPFKNTENIKNSHLK 265
           Q ++NRQK+K      KI   K+   + +  S  + +  K   + K F N ++  NS L 
Sbjct: 21  QQQLNRQKTKEQNSQMKIVHKKKERGHGYNSSAGAWQAMKNGGKNKNFPNNQSW-NSSLS 79

Query: 266 KSAFLTEVSQKENYAGAKFSDPPSPSVLPKPPSHWMGSTVENSNQNRELMAVHLKTLLKV 325
             + L +    +NYAGAKFS+PPSPSVLPKPPSHW+   V  +  ++E+M   LKTLLKV
Sbjct: 80  GPSLLFKSQANQNYAGAKFSEPPSPSVLPKPPSHWV--PVSFNPSDKEIMTFQLKTLLKV 137

Query: 326 Q 326
           Q
Sbjct: 138 Q 138


>gi|8923295 proline-rich nuclear receptor coactivator 2 [Homo
           sapiens]
          Length = 139

 Score = 85.5 bits (210), Expect = 6e-17
 Identities = 50/121 (41%), Positives = 71/121 (58%), Gaps = 5/121 (4%)

Query: 208 QPKINRQKSKYNLPLTKITSAKRNENNFWQDSVSSDRIQKQ--EKKPFKNTENIKNSHLK 265
           Q ++NRQK+K      KI   K+   + +  S ++ +  +   + K F N ++  NS L 
Sbjct: 21  QQQLNRQKTKEQNSQMKIVHKKKERGHGYNSSAAAWQAMQNGGKNKNFPNNQSW-NSSLS 79

Query: 266 KSAFLTEVSQKENYAGAKFSDPPSPSVLPKPPSHWMGSTVENSNQNRELMAVHLKTLLKV 325
               L +    +NYAGAKFS+PPSPSVLPKPPSHW+   V  +  ++E+M   LKTLLKV
Sbjct: 80  GPRLLFKSQANQNYAGAKFSEPPSPSVLPKPPSHWV--PVSFNPSDKEIMTFQLKTLLKV 137

Query: 326 Q 326
           Q
Sbjct: 138 Q 138


>gi|188536004 zinc finger protein 469 [Homo sapiens]
          Length = 3925

 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 43/136 (31%), Positives = 54/136 (39%), Gaps = 11/136 (8%)

Query: 65   GPCLTPQPRAPAALPNRSLAVAGGTPRAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSL 124
            GP  +PQ R P+    RSL          PK   +  V      Q+P+     ++ RPSL
Sbjct: 1136 GPGRSPQARGPS----RSLETGAAAREGGPKCADRPSVAPKDPLQVPTNTETSEETRPSL 1191

Query: 125  E---GGRSPATGPSGAQEVPGPAAALAPSPAAAAGTEGASPDLAPLRPAAPGQTPLRKEV 181
            +     + P T    A +      AL   PAA AG  GASP L  L P  P   P R + 
Sbjct: 1192 DFPQEAKEPETAEESAPDSTEFTEALRSPPAACAGEMGASPGL--LIPEQP--PPSRHDT 1247

Query: 182  LKSKMGKSEKIALPHG 197
               K   S     PHG
Sbjct: 1248 GTPKPSGSLANTAPHG 1263


>gi|92859678 small nuclear RNA activating complex, polypeptide 4,
            190kDa [Homo sapiens]
          Length = 1469

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 39/138 (28%), Positives = 55/138 (39%), Gaps = 15/138 (10%)

Query: 40   PPLPRIPDPRALPPTLFLPHFLGGDGPCLTPQPRAPAALPNRSLAVAGGTPRAAPKKRRK 99
            PPLP  P  R  P            GP +   P +    P  +     G+ + A    + 
Sbjct: 931  PPLPHTPHGRPAP------------GPTVLNVPLSGPGAPAAAKPGTSGSWQEAGTSAKD 978

Query: 100  KKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATGPSGAQEVPGPAAALAPSPAAAAGTEG 159
            K++    A  L   F + +   P+    ++PA GP G   V  P + L  S A AA  + 
Sbjct: 979  KRLSTMQALPLAPVFSEAEGTAPA--ASQAPALGP-GQISVSCPESGLGQSQAPAASRKQ 1035

Query: 160  ASPDLAPLRPAAPGQTPL 177
              P+  P  PAAP  TPL
Sbjct: 1036 GLPEAPPFLPAAPSPTPL 1053



 Score = 28.9 bits (63), Expect = 6.5
 Identities = 19/53 (35%), Positives = 31/53 (58%), Gaps = 3/53 (5%)

Query: 122 PSLEGGRSPATGPSGAQEVPGPAAALAPSPAAAAGTEGASPDLAPLRPAAPGQ 174
           P+ +    P  G +GA  + GPAA+L+P P  ++ ++G S + A    AAPG+
Sbjct: 574 PARQSTSQPWRGGAGAW-LGGPAASLSP-PKGSSASQGGSKE-ASTTAAAPGE 623



 Score = 28.9 bits (63), Expect = 6.5
 Identities = 48/170 (28%), Positives = 63/170 (37%), Gaps = 18/170 (10%)

Query: 14   LGGRLAPLGFSSRGYFGALPMVTTAPPPLPRIPDPRALPPTLFLPHFLGGDGP-----CL 68
            LG   AP     +G   A P +  AP P P    P +L   +  PH +    P      L
Sbjct: 1023 LGQSQAPAASRKQGLPEAPPFLPAAPSPTPLPVQPLSL-THIGGPH-VATSVPLPVTWVL 1080

Query: 69   TPQPRAPAALPN-RSLAVAGGTPRAAPKKRR----KKKVRASPAGQLPSRFHQYQQHRPS 123
            T Q   P  +P   SL    GTP  A           + RA+   + P+    +Q   P 
Sbjct: 1081 TAQGLLPVPVPAVVSLPRPAGTPGPAGLLATLLPPLTETRAAQGPRAPALSSSWQ---PP 1137

Query: 124  LEGGRSPATGPSGAQEVPGPAA-ALAPSPAAAAGTEGASPDLAPLRPAAP 172
                R P   PS   + P P   AL+ SPA A G+    P  A +    P
Sbjct: 1138 ANMNREPE--PSCRTDTPAPPTHALSQSPAEADGSVAFVPGEAQVAREIP 1185


>gi|171543895 ataxin 2 [Homo sapiens]
          Length = 1313

 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 79/331 (23%), Positives = 116/331 (35%), Gaps = 60/331 (18%)

Query: 22  GFSSRGYFGALPMVTTAPPPLPRIPD-----PRALPPTLFLPHFLGGDGPCLTPQPRAPA 76
           G   R   G +P  +  P P  R P      P +LPP    P          T  P  P 
Sbjct: 540 GSDQRVVNGGVPWPSPCPSPSSRPPSRYQSGPNSLPPRAATP----------TRPPSRPP 589

Query: 77  ALPNR--SLAVAGGTPRAAPKKRRKKKV------RASPAGQLPSRFHQYQQHRPSLEGGR 128
           + P+R  S   A G+P  AP     K++      R SP  Q   R H+    R S+  G 
Sbjct: 590 SRPSRPPSHPSAHGSP--APVSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGL 647

Query: 129 SPATGPSGAQEVPGPAAALAPSPAAAAGTEGASPDLAPL--RPAAP-----GQTPLRKEV 181
              +    ++    P A  +PS    +      P L+P   RP +P     G TP    +
Sbjct: 648 EFVSHNPPSEAATPPVARTSPSGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVL 707

Query: 182 LKSKMG--KSEKIALP------------------HGQLVHGIHLYEQPKINRQKSKYNL- 220
              + G   +E +A+P                           L +Q + +   +K N+ 
Sbjct: 708 ASPQAGIIPTEAVAMPIPAASPTPASPASNRAVTPSSEAKDSRLQDQRQNSPAGNKENIK 767

Query: 221 PLTKITSAKRNENNFWQDSVSSDRIQKQEKKPFKNTENIKNSHLKKSAFLTEVSQKENYA 280
           P     S  + EN      VS  R Q  + K FKN   ++ S   +S    +    +N  
Sbjct: 768 PNETSPSFSKAENKGISPVVSEHRKQIDDLKKFKNDFRLQPSSTSES---MDQLLNKNRE 824

Query: 281 GAKFSDPPSPSVLPKPPSHWMGSTVENSNQN 311
           G K  D     + P        S +ENS+ N
Sbjct: 825 GEKSRDLIKDKIEPSAKD----SFIENSSSN 851



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 51/220 (23%), Positives = 89/220 (40%), Gaps = 37/220 (16%)

Query: 84  AVAGGTPRAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATGPSGAQEVPGP 143
           +V  G PR +PK  R +  R +  G  PS         P L    SP  G    + V  P
Sbjct: 675 SVVSGVPRLSPKTHRPRSPRQNSIGNTPS--------GPVL---ASPQAGIIPTEAVAMP 723

Query: 144 AAALAPSPAAAAGTEGASPDLAPLRPAAPGQTPLRKEVLKSKMGKSEKIALPHGQLVHGI 203
             A +P+PA+ A     +P       +    + L+ +   S  G  E I  P+       
Sbjct: 724 IPAASPTPASPASNRAVTPS------SEAKDSRLQDQRQNSPAGNKENIK-PN------- 769

Query: 204 HLYEQPKINRQKSKYNLPLT-----KITSAKRNENNF----WQDSVSSDRIQKQEKKPFK 254
                P  ++ ++K   P+      +I   K+ +N+F       S S D++  + ++  K
Sbjct: 770 --ETSPSFSKAENKGISPVVSEHRKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEK 827

Query: 255 NTENIKNSHLKKSAFLTEVSQKENYAGAKFSDPPSPSVLP 294
           + + IK+  ++ SA  + +    +   +  S P SPS+ P
Sbjct: 828 SRDLIKDK-IEPSAKDSFIENSSSNCTSGSSKPNSPSISP 866



 Score = 33.5 bits (75), Expect = 0.26
 Identities = 68/289 (23%), Positives = 103/289 (35%), Gaps = 76/289 (26%)

Query: 20  PLGFSSRGYFGALP--MVTTAPPPLPRIPDP--RALPPTL-------------FLP---H 59
           P   S RG  GA P    + APPP    P P  ++ PP+              F P    
Sbjct: 34  PARRSGRGGGGAAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFRPGSRR 93

Query: 60  FLGGDGP------CLTP--QPRAPAALPNRSLAV----------------AGGTPRAAP- 94
            LG  GP       L P   P AP A P R+  +                A G PR A  
Sbjct: 94  LLGLGGPPRPFVVLLLPLASPGAPPAAPTRASPLGARASPPRSGVSLARPAPGCPRPACE 153

Query: 95  ----------KKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGR---------SPATGPS 135
                     K +++++ +     Q   +  Q QQ  P+    R         SPA  PS
Sbjct: 154 PVYGPLTMSLKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPS 213

Query: 136 GAQEVPGPAAALAPSPAAAAGTEGASPDLAPLRPAAPG--QTPLRKE----------VLK 183
            +      ++A APS   AA + G  P L   R +  G  Q+ +  +          +L 
Sbjct: 214 PSSSSVSSSSATAPSSVVAATSGGGRPGLGRGRNSNKGLPQSTISFDGIYANMRMVHILT 273

Query: 184 SKMGKSEKIALPHGQLVHGIHLYEQPKINRQKSKYNLPLTKITSAKRNE 232
           S +G   ++ + +G +  G+     PK +      +   T+ +S  + E
Sbjct: 274 SVVGSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHEKSTESSSGPKRE 322


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 45/159 (28%), Positives = 60/159 (37%), Gaps = 17/159 (10%)

Query: 31  ALPMVTTAPPPLPRIPDPRALPPTLFLPHFLGGDGPCLTPQPRAPAALPNRSLAVAGGTP 90
           A+ +V   P  L  +P P A    +  P F+G   P     P  PAA    + A A   P
Sbjct: 214 AVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPP 273

Query: 91  RAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPAT--------GPSGAQEVPG 142
             AP    +      PAG  P+          +  GG + A         GP+G    PG
Sbjct: 274 PPAPATLARPP--GHPAGP-PTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPG 330

Query: 143 P-AAALAPSPAAAAGT-----EGASPDLAPLRPAAPGQT 175
           P AAA AP+P   A +     + A P    L  + P  T
Sbjct: 331 PGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPAST 369



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 43/157 (27%), Positives = 51/157 (32%), Gaps = 34/157 (21%)

Query: 43  PRIPDPRALPPTLFLPHFLGGD-------GPCLTPQPRAPAALPN-----RSLAVAGGTP 90
           PR P+ RA        H + G        GP   P   AP A P      R+    GG  
Sbjct: 45  PRTPEVRAAAAGALGNHVVSGSPAGAAGAGPA-APAEGAPGAAPEPPPAGRARPGGGGPQ 103

Query: 91  RAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRS--------------PATGPSG 136
           R  P   R+  V A PA             RP  EG                 P   P+G
Sbjct: 104 RPGPPSPRRPLVPAGPAPPAAKL-------RPPPEGSAGSCAPVPAAAAVAAGPEPAPAG 156

Query: 137 AQEVPGPAAALAPSPAAAAGTEGASPDLAPLRPAAPG 173
             +  GPAA  A +        G  P   P +PA PG
Sbjct: 157 PAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPG 193



 Score = 34.3 bits (77), Expect = 0.16
 Identities = 57/188 (30%), Positives = 65/188 (34%), Gaps = 34/188 (18%)

Query: 9   REPLVLGG------RLAPLGFSSRGYFGALPM---VTTAPPPLPRIPDPRALPPTLFLPH 59
           R PLV  G      +L P    S G    +P    V   P P P  P   A P  L    
Sbjct: 111 RRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARA 170

Query: 60  FLG---GDGPCLTPQPRAPAA-----LPNRSLAVAGGTPRAAPKKRRKKKVRASPAGQLP 111
             G   G GP   P P  PA        N S A+      AAP       V   PA  LP
Sbjct: 171 GPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAV---SLVNNGPAALLP 227

Query: 112 SRFHQYQQHRPSLEGGRSPATGPSGAQEVPGPAAA---LAPSPAAAAGTEGASPDLAPLR 168
                    +P+  G         GA   P PAA     AP+PAA A    A+P   P  
Sbjct: 228 LP-------KPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPA----AAPPPPPPA 276

Query: 169 PAAPGQTP 176
           PA   + P
Sbjct: 277 PATLARPP 284



 Score = 32.7 bits (73), Expect = 0.45
 Identities = 40/160 (25%), Positives = 45/160 (28%), Gaps = 38/160 (23%)

Query: 33  PMVTTAPPPLPRIPDPRALPP----------------TLFLPHFLGGDGPCLTPQPRAPA 76
           P V  A PP P  P P A P                 TL  P       P   P    PA
Sbjct: 242 PFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPA 301

Query: 77  ALPNRSLAVAGGTPRAAPKKRRKKKVRASPA-------------GQLPSRFHQYQQHRPS 123
           A  N   A  G  P  AP       V   P               + P R  Q       
Sbjct: 302 AAQNGGSA--GAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQ 359

Query: 124 LEGGRSPAT-------GPSGAQEVPGPAAALAPSPAAAAG 156
                 PA+       GP+    +P PAA   P+P    G
Sbjct: 360 TLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTG 399


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 49/148 (33%), Positives = 60/148 (40%), Gaps = 26/148 (17%)

Query: 33   PMVTTAPPPL--PRIPDPRALP--PTLFLPHFLGGDGPCLTPQPRAPAALPNRSLAVAGG 88
            P   T P P   P  P P+  P  P +  P   G   P  TP P+  +  P  +     G
Sbjct: 988  PPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGS--PAATPFPKGASTPPAATPPSPKG 1045

Query: 89   TPRAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATGPSGAQEVPGPAAALA 148
            +P A P     K    +PA  LPS            +GG  PAT PS  +  P P AA  
Sbjct: 1046 SPAATPLP---KGAPTTPAATLPSP-----------KGG--PAT-PS-LKGAPTPPAATP 1087

Query: 149  PSPAAAAGTEGASPDLAPLRPAAPGQTP 176
            PSP     T   SP  AP+ PAA   +P
Sbjct: 1088 PSPKGGPATP--SPKGAPMPPAATPPSP 1113



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 49/171 (28%), Positives = 63/171 (36%), Gaps = 23/171 (13%)

Query: 33   PMVTTAPPPLPR----IPDPRALP--PTLFLPHFLGGDGPCLTPQPRAPAALPNRSLAVA 86
            P    A PP P+     P P+  P  P    P   GG     TP P+     P  +    
Sbjct: 1195 PTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG---LATPSPKGAPTTPAATPPSP 1251

Query: 87   GGTPRAAPKKRRKKKVRASPA---GQLPSRFHQYQQHR-----PSLEGGRSPATGPSGAQ 138
             G P   P K       A+P    G L +  H+   +      PS +GG  PAT P   +
Sbjct: 1252 KGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGG--PATSPP--K 1307

Query: 139  EVPGPAAALAPSPAAAAGTEG--ASPDLAPLRPAAPGQTPLRKEVLKSKMG 187
              P P AA  PSP  + GT     +P    + P +P  TP       S  G
Sbjct: 1308 GAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKG 1358



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 50/157 (31%), Positives = 62/157 (39%), Gaps = 23/157 (14%)

Query: 33  PMVTTAP-PPLPR-IPDPRALPPT----LFLPHFLGGDGPCLTPQPRAPAALPNRSLAVA 86
           P  T +P PP P+  P P A+ P     + LP       P  TP P     LP      A
Sbjct: 850 PATTHSPTPPSPKGAPTPSAVTPLSPKGVTLP-------PKETPTPSV-VNLPFPKEGPA 901

Query: 87  GGTPRAAPK----KRRKKKVRASPAGQ-LPSRFHQYQQHRPSLEGGRSPATGPS--GAQE 139
              P+ AP         KK RA+PA + +P+         P      SP  GP+    + 
Sbjct: 902 TPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKW 961

Query: 140 VPGPAAALAPSPAAAAGTEGASPDLAPLRPAAPGQTP 176
            P P AA  PSP     T   SP  AP  PAA   +P
Sbjct: 962 APTPPAATPPSPKGGPATP--SPKGAPTPPAATPPSP 996



 Score = 37.4 bits (85), Expect = 0.018
 Identities = 39/142 (27%), Positives = 53/142 (37%), Gaps = 21/142 (14%)

Query: 39   PPPLPRIPDPRALPPTL----FLPHFLGGDGPCLT--PQPRA-PAALPNRSL----AVAG 87
            PPP      P A PP+L      P   G   P +   P P+  PA  P +      A   
Sbjct: 1258 PPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATP 1317

Query: 88   GTPRAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATGPSGAQEVPGPAAAL 147
             +P+ +P     K     PA   PS      +  P+L     PAT PS       P++  
Sbjct: 1318 PSPKGSPGTPPPKGAPTPPAVTPPS-----PKGTPTL-----PATTPSSKGGPTTPSSKE 1367

Query: 148  APSPAAAAGTEGASPDLAPLRP 169
             P+P AA  +    P + P  P
Sbjct: 1368 GPTPPAATPSHKGGPAMTPPSP 1389



 Score = 37.0 bits (84), Expect = 0.024
 Identities = 43/147 (29%), Positives = 53/147 (36%), Gaps = 38/147 (25%)

Query: 31   ALPMVTTAPPPLPRIPDPRALPPTLFLPHFLGGDGPCLTPQPRAPAALPNRSLAVAGGTP 90
            AL M +++P      P P+ +P +           P     P  PAA P         +P
Sbjct: 910  ALSMTSSSPKKARATPAPKGIPAS-----------PSPKGAPTPPAATPP--------SP 950

Query: 91   RAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPAT-GPSGAQEVPGPAAALAP 149
            +  P     K     PA   PS            +GG  PAT  P GA   P P AA  P
Sbjct: 951  KGGPATPSPKWAPTPPAATPPSP-----------KGG--PATPSPKGA---PTPPAATPP 994

Query: 150  SPAAAAGTEGASPDLAPLRPAAPGQTP 176
            SP     T   SP  AP  PA    +P
Sbjct: 995  SPKGGPATP--SPKGAPTPPAVTPPSP 1019



 Score = 37.0 bits (84), Expect = 0.024
 Identities = 46/179 (25%), Positives = 59/179 (32%), Gaps = 20/179 (11%)

Query: 24   SSRGYFGALPMVTTAPPPLPRIPDPRALPPT-LFLPHFLGGDG-PCLTPQPRAPAALPNR 81
            S +G  G  P      PP    P P+  P      P   GG   P     P  PAA P+ 
Sbjct: 1319 SPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSH 1378

Query: 82   SLAVAGGTPRAAPKKRRKKKVRASPAGQ--LPSRFHQYQQHRPSLEGGRSPATGPSGAQE 139
                  G P   P   ++     SP G    P+      +  P+    R  A  PS    
Sbjct: 1379 K-----GGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDL 1433

Query: 140  VPGPA----------AALAPSPAAAAGTEGASPDLAPLRPAAPGQTPLRKEVLKSKMGK 188
             P PA          A  AP    A  +    P L  + P +P + P  K+V  S   K
Sbjct: 1434 TP-PAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPK 1491



 Score = 31.6 bits (70), Expect = 1.0
 Identities = 44/166 (26%), Positives = 64/166 (38%), Gaps = 33/166 (19%)

Query: 34   MVTTAPPPLPRIPDPRALP--PTLFL-----PHFLGGDGPCLTPQPRAPAALPNRSLAVA 86
            ++ ++P  +P  P  R  P  PT  L     P  L      + P    P+  P ++ A+ 
Sbjct: 1508 VIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPS--PKKTPAIP 1565

Query: 87   GGTPRAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATGPSGAQEVPGPAAA 146
              TP+ AP     K+  +SP    PS +          +G  SP       +E+  P A 
Sbjct: 1566 --TPKEAPATPSSKEA-SSPPAVTPSTY----------KGAPSP-------KELLIPPAV 1605

Query: 147  LAPSPAAA---AGTEGASPDLAPLRPAAPGQTPLRKEVLKSKMGKS 189
             +PSP  A         SP+  P  PA  G TP    V  S +  S
Sbjct: 1606 TSPSPKEAPTPPAVTPPSPEKGPATPAPKG-TPTSPPVTPSSLKDS 1650



 Score = 30.8 bits (68), Expect = 1.7
 Identities = 39/147 (26%), Positives = 52/147 (35%), Gaps = 12/147 (8%)

Query: 30  GALPMVTTAPPPLPRIPDPRALPPTLFLPHFLGGDGPCLTPQPRAPAALPNRSLAVAGGT 89
           G  P+V T P  +   P       T   P      GP    +P +PAAL    +A    +
Sbjct: 437 GTTPLVVTNPCTIAAAPTTTFEVATCVSPPM--SSGPISNIEPTSPAALVMAPVAPKEPS 494

Query: 90  PRAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATGPSGAQEVPGPAAALAP 149
            + A   R    +  SP    P       ++ PS    + P       Q VP        
Sbjct: 495 TQVATTLR----IPVSPPLPDPEDL----KNLPSSVLVKFPTQ--KDLQTVPASLEGAPF 544

Query: 150 SPAAAAGTEGASPDLAPLRPAAPGQTP 176
           SPA A  T    P + PL  AAP  +P
Sbjct: 545 SPAQAGLTTKKDPTVLPLVQAAPKNSP 571



 Score = 28.5 bits (62), Expect = 8.5
 Identities = 20/56 (35%), Positives = 27/56 (48%), Gaps = 5/56 (8%)

Query: 127 GRSPATGPSGAQEVPGPAAALAPSPAAAAGTEGAS-----PDLAPLRPAAPGQTPL 177
           G +  T P+  QE+P P A  A  P ++A +  A+     P L P    AP Q PL
Sbjct: 3   GEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPL 58


>gi|16950645 neurotrophic factor artemin isoform 2 [Homo sapiens]
          Length = 237

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 50/175 (28%), Positives = 68/175 (38%), Gaps = 12/175 (6%)

Query: 34  MVTTAPPPLPRIPDPRALPPTLFLPHFLGGDG--PCLTPQPRAPAALPNRSLAVAGGTPR 91
           +++    PL  +  P+A    LFLP    G    P L P   A A L + + A  G  PR
Sbjct: 4   LISARGQPLLEVLPPQAHLGALFLPEAPLGLSAQPALWPTLAALALLSSVAEASLGSAPR 63

Query: 92  AAPKKRRKKKVRASPAGQLP----SRFHQYQQHRPSLEGGRSPATGPSGAQEVP-GPAAA 146
           +   +     V ASPAG LP    +R+   +  RP  +  R     P+    +P G  AA
Sbjct: 64  SPAPREGPPPVLASPAGHLPGGRTARWCSGRARRPPPQPSRPAPPPPAPPSALPRGGRAA 123

Query: 147 LAPSP---AAAAGTEGA--SPDLAPLRPAAPGQTPLRKEVLKSKMGKSEKIALPH 196
            A  P   A AAG  G      L P+R    G         +   G   +   PH
Sbjct: 124 RAGGPGSRARAAGARGCRLRSQLVPVRALGLGHRSDELVRFRFCSGSCRRARSPH 178


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 50/156 (32%), Positives = 56/156 (35%), Gaps = 23/156 (14%)

Query: 33  PMVTTAPPPLPRIPDPRALPPTLFLPHFLGGD--GPCLTPQPRAPAALPNRSLAVAGGTP 90
           PM  +A PP P+ P P A PP    P         P  TP PR P  L    L V    P
Sbjct: 715 PMSPSATPP-PQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPP 773

Query: 91  RAAPKKRRKKKVRASPAG----------QLPSRFHQYQQHRPSLEGGRSP-ATGPSGAQE 139
            + P     K    +P              P+ F       PS     SP AT P  A  
Sbjct: 774 ASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPP 833

Query: 140 V-PGPAAALAPSPAAAAGTEGASPDL-APLRPAAPG 173
           V   P   + PSP        ASP L AP RP  PG
Sbjct: 834 VLAAPLLQVPPSPP-------ASPTLQAPRRPPTPG 862



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 43/150 (28%), Positives = 57/150 (38%), Gaps = 15/150 (10%)

Query: 35  VTTAPPPLPR---IPDPRALPPTLFLPHFLGGDGPCL----TPQPRAPAALPNRSLAVAG 87
           +TT PP  P     P P+A PP L  P   G   P L    TP P+AP  L    L    
Sbjct: 576 LTTPPPETPSSIATPPPQA-PPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPP 634

Query: 88  GTPRAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATGPSGAQEVPGPAAAL 147
             P + P         A+P+ Q P+    +    P       P   P      P P +  
Sbjct: 635 SPPASPPLSPL-----ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP-PVSPS 688

Query: 148 APSPAAAAGTEGASP-DLAPLRPAAPGQTP 176
           A  P+ A  +  A P  + P  PA+P  +P
Sbjct: 689 ATPPSQAPPSLAAPPLQVPPSPPASPPMSP 718



 Score = 38.5 bits (88), Expect = 0.008
 Identities = 43/140 (30%), Positives = 54/140 (38%), Gaps = 21/140 (15%)

Query: 31  ALPMVTTAPPPLPRIPDPRALPPTLFLPHFLGGDGPCLTPQPRAPAALPNRSLAVAGGTP 90
           +LPM   A PP P+ P   A PP   LP          +P    P   P    A    +P
Sbjct: 775 SLPMSPLAKPP-PQAPPALATPPLQALP----------SPPASFPGQAPFSPSASLPMSP 823

Query: 91  RAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPAT-GPSGAQEVPGPAAALAP 149
            A P  +    V A+P  Q+P          P+L+  R P T GP  +   P    ALAP
Sbjct: 824 LATPPPQAPP-VLAAPLLQVPPS----PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP 878

Query: 150 SPAAAAGTEGAS----PDLA 165
            P        +S    PDLA
Sbjct: 879 GPPPPPSRSPSSTLSGPDLA 898



 Score = 37.7 bits (86), Expect = 0.014
 Identities = 42/145 (28%), Positives = 50/145 (34%), Gaps = 20/145 (13%)

Query: 38  APPPLPRIPDPRALPPTLFLPHFLGGD--------GPCLTPQPRAPAALPNRSLAVAGGT 89
           +PP  P    P   PP+L  P               P  TP P+AP  L    L V    
Sbjct: 682 SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSP 741

Query: 90  PRAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATGPSGAQEVPGPAA--AL 147
           P + P          SP+   P R        P       PA+ P      P P A  AL
Sbjct: 742 PASPP---------MSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPAL 792

Query: 148 APSPAAAAGTEGAS-PDLAPLRPAA 171
           A  P  A  +  AS P  AP  P+A
Sbjct: 793 ATPPLQALPSPPASFPGQAPFSPSA 817



 Score = 34.7 bits (78), Expect = 0.12
 Identities = 54/190 (28%), Positives = 64/190 (33%), Gaps = 46/190 (24%)

Query: 34  MVTTAPPPLPRIPDPRALPPTLF------------LPHFLGGDGPCLTPQPRAPAALPNR 81
           ++T  PP  PR P P   P  L             L    GG G    P+  AP A P R
Sbjct: 24  LLTPRPPGSPR-PPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPES-APRAGPTR 81

Query: 82  SLAVAGGTP-----------RAAPKK-----------RRKKKVRASPAGQLPSRFHQYQQ 119
           S   +   P           RA P K           R     R  P GQ   R    + 
Sbjct: 82  SAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEET 141

Query: 120 --HRPSLEGGRSPATGPSGAQEVPGPAAALAPSPAAA-----AGTEGASPDLAP-LRPAA 171
                + E  +  A      ++  GP     PSPA A     AGTE   P  AP  RP  
Sbjct: 142 VARGKATEAPKRSALSAGARRDTSGPTPG-TPSPAMARRSRAAGTEVGLPRPAPSARPRP 200

Query: 172 PGQTPLRKEV 181
           P + P RK V
Sbjct: 201 PTEGP-RKSV 209



 Score = 31.6 bits (70), Expect = 1.0
 Identities = 36/142 (25%), Positives = 55/142 (38%), Gaps = 9/142 (6%)

Query: 33  PMVTTAPPPLPRIPDPRA-----LPPTLFLPHFLGGDGPCLTPQPRAPAALPNRSLAVAG 87
           P   +APP L  +P P A      PP++  P           P  + P +L + SL  A 
Sbjct: 345 PPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQ-AP 403

Query: 88  GTPRAAPKKRRKKKVRASPAGQLPSRF--HQYQQHRPSLEGGRSPATGPSGAQEVPGPAA 145
            +P A    +    +  SP  Q    F     +Q + SL     PA+ P  +  +  P +
Sbjct: 404 PSPLALSSLQATTSL-GSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLS 462

Query: 146 ALAPSPAAAAGTEGASPDLAPL 167
             A  P   + +   SP  +PL
Sbjct: 463 LPASPPLQTSLSPAVSPLSSPL 484



 Score = 30.8 bits (68), Expect = 1.7
 Identities = 30/103 (29%), Positives = 40/103 (38%), Gaps = 9/103 (8%)

Query: 75  PAALPNRSLAVAGGTPRAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATGP 134
           P + P RS   A GTPRA     + K     P G    R  Q    R       +PA GP
Sbjct: 248 PLSSPARSGPSARGTPRAPAHPSQPK-----PKGLQALRPPQVTPPRKDA----APALGP 298

Query: 135 SGAQEVPGPAAALAPSPAAAAGTEGASPDLAPLRPAAPGQTPL 177
             +  +  P+ +   +         A+P  A L P+ P  TPL
Sbjct: 299 LSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPL 341



 Score = 30.8 bits (68), Expect = 1.7
 Identities = 53/176 (30%), Positives = 72/176 (40%), Gaps = 35/176 (19%)

Query: 27  GYFGALPMVTTAPP-----PLPRIPDPRALPPTLFLPHFLGGDGPCLTPQPRA---PAAL 78
           G   + P+ T +P      P+P  PD  A P    LP  L    P  TP P A   P+A 
Sbjct: 297 GPLSSSPLATPSPSGTKARPVPP-PDNAATP----LPATLPPSPPLATPLPLAPPSPSAP 351

Query: 79  PN-RSLAVAGGTPRA-APKKRRKKKVRASPAGQ-LPSRFHQYQQHRPSLEGGRSP----- 130
           P+ ++L     TP + AP       ++A P+ Q +P     +    PSL+   SP     
Sbjct: 352 PSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSS 411

Query: 131 --ATGPSGAQEV----------PGPAAALAPSPAAAAGTEGASPDL-APLR-PAAP 172
             AT   G+  +          P    A   SP+  A T   SP L APL  PA+P
Sbjct: 412 LQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASP 467


>gi|9945318 MAX binding protein [Homo sapiens]
          Length = 582

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 87/327 (26%), Positives = 115/327 (35%), Gaps = 79/327 (24%)

Query: 32  LPMVTTAPPPLPRIPDPRALP-PTLFLPHFLGGDGP-CLTPQPRAPAALPNRSLAVAGGT 89
           LP+   APPP P  P P A P P   +P  +  + P  L P P  PAA     LA     
Sbjct: 65  LPLSPPAPPPAP--PPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAAQPLPLAPRQPA 122

Query: 90  PRAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRS---PATGPSGAQEVPGPAAA 146
              AP    K+     PA  LPSR  Q     P L   ++   P   P   Q +P P   
Sbjct: 123 LVGAPGLSIKE-----PA-PLPSR-PQVPTPAPLLPDSKATIPPNGSPKPLQPLPTPVLT 175

Query: 147 LAPSPAAAAGTEGASPDLAPLRPAAPGQTPLRKEVLKSKMGKSEKIALPHG---QLVHG- 202
           +AP P       G  P LAP +P  P    L K     ++  SE+   P G   + VH  
Sbjct: 176 IAPHP-------GVQPQLAPQQPPPPTLGTL-KLAPAEEVKSSEQKKRPGGIGTREVHNK 227

Query: 203 ------IHLYE--------QPKINRQK----SKYNLPLTKITSAKRNENNF--------- 235
                  HL E         P ++ +K    S     L  I S KR E  +         
Sbjct: 228 LEKNRRAHLKECFETLKRNIPNVDDKKTSNLSVLRTALRYIQSLKRKEKEYEHEMERLAR 287

Query: 236 ------------------WQDSVSSDRIQKQEKKPFKNTENIKNSHLKKSAFLTEVSQKE 277
                             W D +  DR+ +Q  +P    +    S   +     +   +E
Sbjct: 288 EKIATQQRLAELKHELSQWMDVLEIDRVLRQTGQP--EDDQASTSTASEGEDNIDEDMEE 345

Query: 278 NYAG---AKFSDPPSPSVLPK---PPS 298
           + AG    K S  P P +L     PPS
Sbjct: 346 DRAGLGPPKLSHRPQPELLKSTLPPPS 372



 Score = 31.6 bits (70), Expect = 1.0
 Identities = 37/132 (28%), Positives = 45/132 (34%), Gaps = 28/132 (21%)

Query: 32  LPMVTTAPPPLPRIPDPR----ALPPTLFLPHFLGGDGPCLTPQPRAPAALPNRSLAVAG 87
           LP  +T P PLP  P P     ALPP            P    QP+    LP      A 
Sbjct: 368 LPPPSTTPAPLPPHPHPHPHSVALPPAHL---------PVQQQQPQQKTPLP------AP 412

Query: 88  GTPRAAPKKR---RKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATGPSG------AQ 138
             P AAP +        + A+  G      H    H   ++       GP G      A 
Sbjct: 413 PPPPAAPAQTLVPAPAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQGPGGKHIAHIAP 472

Query: 139 EVPGPAAALAPS 150
             P PA  LAP+
Sbjct: 473 SAPSPAVQLAPA 484


>gi|42475970 synapse defective 1, Rho GTPase, homolog 1 [Homo
           sapiens]
          Length = 735

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 44/150 (29%), Positives = 61/150 (40%), Gaps = 39/150 (26%)

Query: 41  PLPRIPDPRALPPTLFLPHFLGGDGPCLTPQPRAPAALPNRSLAVAGGTP--------RA 92
           P+P   DPR   P    P     +   L PQ  APA+ P ++       P        + 
Sbjct: 114 PIPE-EDPRPPAPEPPGPQPGSAESEGLAPQGAAPASPPTKASRTKSPGPARRLSIKMKK 172

Query: 93  APKKRRK----------KKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATGPSGAQEVPG 142
            P+ RR+          ++ RA+PAG + SR+H       S  GG  PA GP G +    
Sbjct: 173 LPELRRRLSLRGPRAGRERERAAPAGSVISRYHL-----DSSVGGPGPAAGPGGTR---- 223

Query: 143 PAAALAPSPAAAAGTEGASPDLAPLRPAAP 172
                  SP A   ++G SP+    RPA P
Sbjct: 224 -------SPRAGYLSDGDSPE----RPAGP 242


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 45/158 (28%), Positives = 59/158 (37%), Gaps = 20/158 (12%)

Query: 33  PMVTTAPPPLPRIPDPRALP----------PTLFLPH-FLGGD--GPCLTPQPRAPAALP 79
           P   +APP L  +P P A P          PTL   H FL      P  TP P+AP AL 
Sbjct: 342 PPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALA 401

Query: 80  NRSLAVAGGTPRAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATGPSGAQE 139
              L      P + P         A+P+ Q P+    +    P       P   P     
Sbjct: 402 LPPLQAPPSPPASPP-----LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 456

Query: 140 VPGPAAALAPSPAAAAGTEGASP-DLAPLRPAAPGQTP 176
            P P +  A  P+ A  +  A P  + P  PA+P  +P
Sbjct: 457 SP-PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP 493



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 47/147 (31%), Positives = 57/147 (38%), Gaps = 21/147 (14%)

Query: 38  APPPLPRIPDPRALPPTLFLPHFLGGD--------GPCLTPQPRAPAALPNRSLAVAGGT 89
           +PP  P    P   PP+L  P               P  TP P+AP  L    L +A   
Sbjct: 457 SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPP 516

Query: 90  PRAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSP-ATGPSGAQEV-PGPAAAL 147
           P+ AP       ++A P+   P+ F       PS     SP AT P  A  V   P   +
Sbjct: 517 PQ-APPALATPPLQALPSP--PASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQV 573

Query: 148 APSPAAAAGTEGASPDL-APLRPAAPG 173
            PSP        ASP L AP RP  PG
Sbjct: 574 PPSPP-------ASPTLQAPRRPPTPG 593



 Score = 37.0 bits (84), Expect = 0.024
 Identities = 45/149 (30%), Positives = 60/149 (40%), Gaps = 25/149 (16%)

Query: 33  PMVTTAPPPLPRIPDPRALPPTLF------LPHFLGGDGPCLTPQPRAPAALPNRS---- 82
           PM  +A PP P+ P P A PP          P  L    P L   P  PA+ P ++    
Sbjct: 490 PMSPSATPP-PQAPPPLAAPPLQLAKPPPQAPPALA--TPPLQALPSPPASFPGQAPFSP 546

Query: 83  LAVAGGTPRAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATGPSGAQEVPG 142
            A    +P A P   +   V A+P  Q+P          P+L+  R P T P     V G
Sbjct: 547 SASLPMSPLATPPP-QAPPVLAAPLLQVPPS----PPASPTLQAPRRPPT-PGPDTSVSG 600

Query: 143 PAAALA------PSPAAAAGTEGASPDLA 165
           P   LA      P P+ +  +  + PDLA
Sbjct: 601 PRLTLALAPGPPPPPSRSPSSTLSGPDLA 629



 Score = 34.7 bits (78), Expect = 0.12
 Identities = 54/190 (28%), Positives = 64/190 (33%), Gaps = 46/190 (24%)

Query: 34  MVTTAPPPLPRIPDPRALPPTLF------------LPHFLGGDGPCLTPQPRAPAALPNR 81
           ++T  PP  PR P P   P  L             L    GG G    P+  AP A P R
Sbjct: 24  LLTPRPPGSPR-PPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPES-APRAGPTR 81

Query: 82  SLAVAGGTP-----------RAAPKK-----------RRKKKVRASPAGQLPSRFHQYQQ 119
           S   +   P           RA P K           R     R  P GQ   R    + 
Sbjct: 82  SAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEET 141

Query: 120 --HRPSLEGGRSPATGPSGAQEVPGPAAALAPSPAAA-----AGTEGASPDLAP-LRPAA 171
                + E  +  A      ++  GP     PSPA A     AGTE   P  AP  RP  
Sbjct: 142 VARGKATEAPKRSALSAGARRDTSGPTPG-TPSPAMARRSRAAGTEVGLPRPAPSARPRP 200

Query: 172 PGQTPLRKEV 181
           P + P RK V
Sbjct: 201 PTEGP-RKSV 209


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 45/158 (28%), Positives = 59/158 (37%), Gaps = 20/158 (12%)

Query: 33  PMVTTAPPPLPRIPDPRALP----------PTLFLPH-FLGGD--GPCLTPQPRAPAALP 79
           P   +APP L  +P P A P          PTL   H FL      P  TP P+AP AL 
Sbjct: 303 PPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALA 362

Query: 80  NRSLAVAGGTPRAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATGPSGAQE 139
              L      P + P         A+P+ Q P+    +    P       P   P     
Sbjct: 363 LPPLQAPPSPPASPP-----LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 417

Query: 140 VPGPAAALAPSPAAAAGTEGASP-DLAPLRPAAPGQTP 176
            P P +  A  P+ A  +  A P  + P  PA+P  +P
Sbjct: 418 SP-PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP 454



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 47/147 (31%), Positives = 57/147 (38%), Gaps = 21/147 (14%)

Query: 38  APPPLPRIPDPRALPPTLFLPHFLGGD--------GPCLTPQPRAPAALPNRSLAVAGGT 89
           +PP  P    P   PP+L  P               P  TP P+AP  L    L +A   
Sbjct: 418 SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPP 477

Query: 90  PRAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSP-ATGPSGAQEV-PGPAAAL 147
           P+ AP       ++A P+   P+ F       PS     SP AT P  A  V   P   +
Sbjct: 478 PQ-APPALATPPLQALPSP--PASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQV 534

Query: 148 APSPAAAAGTEGASPDL-APLRPAAPG 173
            PSP        ASP L AP RP  PG
Sbjct: 535 PPSPP-------ASPTLQAPRRPPTPG 554



 Score = 37.0 bits (84), Expect = 0.024
 Identities = 45/149 (30%), Positives = 60/149 (40%), Gaps = 25/149 (16%)

Query: 33  PMVTTAPPPLPRIPDPRALPPTLF------LPHFLGGDGPCLTPQPRAPAALPNRS---- 82
           PM  +A PP P+ P P A PP          P  L    P L   P  PA+ P ++    
Sbjct: 451 PMSPSATPP-PQAPPPLAAPPLQLAKPPPQAPPALA--TPPLQALPSPPASFPGQAPFSP 507

Query: 83  LAVAGGTPRAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATGPSGAQEVPG 142
            A    +P A P   +   V A+P  Q+P          P+L+  R P T P     V G
Sbjct: 508 SASLPMSPLATPPP-QAPPVLAAPLLQVPPS----PPASPTLQAPRRPPT-PGPDTSVSG 561

Query: 143 PAAALA------PSPAAAAGTEGASPDLA 165
           P   LA      P P+ +  +  + PDLA
Sbjct: 562 PRLTLALAPGPPPPPSRSPSSTLSGPDLA 590



 Score = 34.7 bits (78), Expect = 0.12
 Identities = 53/181 (29%), Positives = 64/181 (35%), Gaps = 37/181 (20%)

Query: 34  MVTTAPPPLPRIPDPRALPPTLF------------LPHFLGGDGPCLTPQPRAPAALPNR 81
           ++T  PP  PR P P   P  L             L    GG G    P+  AP A P R
Sbjct: 24  LLTPRPPGSPR-PPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPES-APRAGPTR 81

Query: 82  SLA--VAGGTPRAAPKK-----------RRKKKVRASPAGQLPSRFHQYQQ--HRPSLEG 126
           +     +G   RA P K           R     R  P GQ   R    +      + E 
Sbjct: 82  TSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEA 141

Query: 127 GRSPATGPSGAQEVPGPAAALAPSPAAA-----AGTEGASPDLAP-LRPAAPGQTPLRKE 180
            +  A      ++  GP     PSPA A     AGTE   P  AP  RP  P + P RK 
Sbjct: 142 PKRSALSAGARRDTSGPTPG-TPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGP-RKS 199

Query: 181 V 181
           V
Sbjct: 200 V 200



 Score = 30.8 bits (68), Expect = 1.7
 Identities = 30/98 (30%), Positives = 38/98 (38%), Gaps = 14/98 (14%)

Query: 75  PAALPNRSLAVAGGTPRAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATGP 134
           P + P RS   A GTPRA     + K     P G    R  Q    R       +PA GP
Sbjct: 239 PLSSPARSGPSARGTPRAPAHPSQPK-----PKGLQALRPPQVTPPRKDA----APALGP 289

Query: 135 SGAQEVPGPAAALAPSPAAAAGTEGASPDLAPLRPAAP 172
             +  +  P+ +  PSP+A       S    P  PA P
Sbjct: 290 LSSSPLATPSPSAPPSPSAP-----PSLQTLPSPPATP 322


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 48/168 (28%), Positives = 61/168 (36%), Gaps = 22/168 (13%)

Query: 31   ALPMVTT--APPPLPRIPDPRALPPTLFLPHFLGGDGPC----LTPQPRAPAALPNRSLA 84
            A P++ T  +PPP     DP  +PP +  P      GP     + P P   + L   SL 
Sbjct: 974  AAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLV 1033

Query: 85   VAGGTPRAAPKKRRKKKVRA--SPAGQLPSRFHQYQQHRPSLE---GGRSPATGPSGAQE 139
                 P           V +  SP G++     + + H    E       PA  PS    
Sbjct: 1034 PQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSP 1093

Query: 140  VPGPAAAL---APSPAAAAGT-EGASPDLAPL-------RPAAPGQTP 176
            +P P   L   APSPA A     G   D APL           PGQTP
Sbjct: 1094 LPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTP 1141



 Score = 35.8 bits (81), Expect = 0.053
 Identities = 40/169 (23%), Positives = 55/169 (32%), Gaps = 12/169 (7%)

Query: 40  PPLPRIPDPRALPPTLFLPHFLG-GDGPCLTPQPRAPAALPNRSLAVAGGTPRAAPKKRR 98
           P L   P+   L P    PH     + PCL+PQP      P          P  +     
Sbjct: 795 PHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPE 854

Query: 99  KKKVRASP--------AGQLPSRFHQYQQHRPSLEGGRSPATGPSGAQEVPGPAAALAPS 150
            +K   SP         GQ P+   +     P  E   SP  G     E   P  +  P 
Sbjct: 855 LEKPPLSPRPEKPPEEPGQCPAP-EELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPE 913

Query: 151 --PAAAAGTEGASPDLAPLRPAAPGQTPLRKEVLKSKMGKSEKIALPHG 197
             P + +G    SP L P  P  P  +P+        +    ++  P G
Sbjct: 914 ELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFG 962



 Score = 30.0 bits (66), Expect = 2.9
 Identities = 20/57 (35%), Positives = 24/57 (42%), Gaps = 3/57 (5%)

Query: 121  RPSLEGGRSPATGPSGAQEV-PGPAAALAPSPAAAAGTEGASPDLAPLRPAAPGQTP 176
            +P L G   P TGP   QE+  GP     P   A  G     P L P+ P  P  +P
Sbjct: 4260 QPQLGGFPGPQTGP--LQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSP 4314


>gi|239743660 PREDICTED: hypothetical protein XP_002342926 [Homo
           sapiens]
          Length = 329

 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 43/148 (29%), Positives = 58/148 (39%), Gaps = 43/148 (29%)

Query: 48  PRALPPTLFLPHFLGGDGPCLTPQPRA---------------PAALPNRSLAVAGGTPRA 92
           PRA PP        GG G   TP P+A               P+  P R L +    PR 
Sbjct: 207 PRAFPP--------GGPGDAGTPMPKAGGLRKRPGITRTEGNPSPRPPRRLTLPEDHPRL 258

Query: 93  APKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATGPSGAQEVPGPAAALAPSPA 152
           A  +RR+K+  A+             + RP+ +    P  GP G     GPA ++  SPA
Sbjct: 259 ANARRRRKRALAT-------------RVRPAPQTSGRP--GPLG-----GPAISVVLSPA 298

Query: 153 AAAGTEGASPDLAPLRPAAPGQTPLRKE 180
           + A  +G S      R    GQ P R +
Sbjct: 299 SQAPEKGWSQSRGGARLGPEGQEPGRDQ 326


>gi|14602439 Williams Beuren syndrome chromosome region 14 isoform
           delta [Homo sapiens]
          Length = 831

 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 45/156 (28%), Positives = 60/156 (38%), Gaps = 19/156 (12%)

Query: 39  PPPLPRIPDPRAL--PPTLFLPHF---LGGDGPCLTPQPRAPAALPNRSLAVAGGTPRAA 93
           PPP P +  P AL     LF P F        P ++P P APAA P    +V    P   
Sbjct: 412 PPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLP-APAAFPPTPQSVPSPAPTPF 470

Query: 94  PKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATGPSGAQEVPGPAAALAPSPAA 153
           P       +   P G     F        S+  G+ PA  P G +  P   A    SP  
Sbjct: 471 P-------IELLPLGYSEPAFGPCF----SMPRGKPPAPSPRGQKASPPTLAPATASPPT 519

Query: 154 AAGTEGASPDLAPLRPAAPGQTPLRKEVLKSKMGKS 189
            AG+   +P L  L  AA  +  L   ++ S + +S
Sbjct: 520 TAGSN--NPCLTQLLTAAKPEQALEPPLVSSTLLRS 553



 Score = 38.5 bits (88), Expect = 0.008
 Identities = 45/173 (26%), Positives = 58/173 (33%), Gaps = 39/173 (22%)

Query: 2   TVVSVPQREPLVLGGRLAPLGFSSRGYFGALPMVTTAPPPLPRIPDPRALPPTL-----F 56
           T  SVP   P      L PLG+S    FG    +    PP P     +A PPTL      
Sbjct: 458 TPQSVPSPAPTPFPIELLPLGYSEPA-FGPCFSMPRGKPPAPSPRGQKASPPTLAPATAS 516

Query: 57  LPHFLGGDGPCLT-------PQPRAPAALPNRSLAVAGGTPRAAPKKRRKKKVRASPAGQ 109
            P   G + PCLT       P+      L + +L  + G+P        ++ V   P   
Sbjct: 517 PPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSP--------QETVPEFPCTF 568

Query: 110 LPSRFHQYQQHRPSLEGGRSPATGPSGAQEVPGPAAALAPSPAAAAGTEGASP 162
           LP                  P   P+  +  PGPA      P      E  SP
Sbjct: 569 LP------------------PTPAPTPPRPPPGPATLAPSRPLLVPKAERLSP 603


>gi|14602437 Williams Beuren syndrome chromosome region 14 isoform
           gamma [Homo sapiens]
          Length = 850

 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 45/156 (28%), Positives = 60/156 (38%), Gaps = 19/156 (12%)

Query: 39  PPPLPRIPDPRAL--PPTLFLPHF---LGGDGPCLTPQPRAPAALPNRSLAVAGGTPRAA 93
           PPP P +  P AL     LF P F        P ++P P APAA P    +V    P   
Sbjct: 412 PPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLP-APAAFPPTPQSVPSPAPTPF 470

Query: 94  PKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATGPSGAQEVPGPAAALAPSPAA 153
           P       +   P G     F        S+  G+ PA  P G +  P   A    SP  
Sbjct: 471 P-------IELLPLGYSEPAFGPCF----SMPRGKPPAPSPRGQKASPPTLAPATASPPT 519

Query: 154 AAGTEGASPDLAPLRPAAPGQTPLRKEVLKSKMGKS 189
            AG+   +P L  L  AA  +  L   ++ S + +S
Sbjct: 520 TAGSN--NPCLTQLLTAAKPEQALEPPLVSSTLLRS 553



 Score = 38.5 bits (88), Expect = 0.008
 Identities = 45/173 (26%), Positives = 58/173 (33%), Gaps = 39/173 (22%)

Query: 2   TVVSVPQREPLVLGGRLAPLGFSSRGYFGALPMVTTAPPPLPRIPDPRALPPTL-----F 56
           T  SVP   P      L PLG+S    FG    +    PP P     +A PPTL      
Sbjct: 458 TPQSVPSPAPTPFPIELLPLGYSEPA-FGPCFSMPRGKPPAPSPRGQKASPPTLAPATAS 516

Query: 57  LPHFLGGDGPCLT-------PQPRAPAALPNRSLAVAGGTPRAAPKKRRKKKVRASPAGQ 109
            P   G + PCLT       P+      L + +L  + G+P        ++ V   P   
Sbjct: 517 PPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSP--------QETVPEFPCTF 568

Query: 110 LPSRFHQYQQHRPSLEGGRSPATGPSGAQEVPGPAAALAPSPAAAAGTEGASP 162
           LP                  P   P+  +  PGPA      P      E  SP
Sbjct: 569 LP------------------PTPAPTPPRPPPGPATLAPSRPLLVPKAERLSP 603


>gi|14602435 Williams Beuren syndrome chromosome region 14 isoform
           beta [Homo sapiens]
          Length = 833

 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 45/156 (28%), Positives = 60/156 (38%), Gaps = 19/156 (12%)

Query: 39  PPPLPRIPDPRAL--PPTLFLPHF---LGGDGPCLTPQPRAPAALPNRSLAVAGGTPRAA 93
           PPP P +  P AL     LF P F        P ++P P APAA P    +V    P   
Sbjct: 412 PPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLP-APAAFPPTPQSVPSPAPTPF 470

Query: 94  PKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATGPSGAQEVPGPAAALAPSPAA 153
           P       +   P G     F        S+  G+ PA  P G +  P   A    SP  
Sbjct: 471 P-------IELLPLGYSEPAFGPCF----SMPRGKPPAPSPRGQKASPPTLAPATASPPT 519

Query: 154 AAGTEGASPDLAPLRPAAPGQTPLRKEVLKSKMGKS 189
            AG+   +P L  L  AA  +  L   ++ S + +S
Sbjct: 520 TAGSN--NPCLTQLLTAAKPEQALEPPLVSSTLLRS 553



 Score = 38.5 bits (88), Expect = 0.008
 Identities = 45/173 (26%), Positives = 58/173 (33%), Gaps = 39/173 (22%)

Query: 2   TVVSVPQREPLVLGGRLAPLGFSSRGYFGALPMVTTAPPPLPRIPDPRALPPTL-----F 56
           T  SVP   P      L PLG+S    FG    +    PP P     +A PPTL      
Sbjct: 458 TPQSVPSPAPTPFPIELLPLGYSEPA-FGPCFSMPRGKPPAPSPRGQKASPPTLAPATAS 516

Query: 57  LPHFLGGDGPCLT-------PQPRAPAALPNRSLAVAGGTPRAAPKKRRKKKVRASPAGQ 109
            P   G + PCLT       P+      L + +L  + G+P        ++ V   P   
Sbjct: 517 PPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSP--------QETVPEFPCTF 568

Query: 110 LPSRFHQYQQHRPSLEGGRSPATGPSGAQEVPGPAAALAPSPAAAAGTEGASP 162
           LP                  P   P+  +  PGPA      P      E  SP
Sbjct: 569 LP------------------PTPAPTPPRPPPGPATLAPSRPLLVPKAERLSP 603


>gi|14602433 Williams Beuren syndrome chromosome region 14 isoform
           alpha [Homo sapiens]
          Length = 852

 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 45/156 (28%), Positives = 60/156 (38%), Gaps = 19/156 (12%)

Query: 39  PPPLPRIPDPRAL--PPTLFLPHF---LGGDGPCLTPQPRAPAALPNRSLAVAGGTPRAA 93
           PPP P +  P AL     LF P F        P ++P P APAA P    +V    P   
Sbjct: 412 PPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLP-APAAFPPTPQSVPSPAPTPF 470

Query: 94  PKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATGPSGAQEVPGPAAALAPSPAA 153
           P       +   P G     F        S+  G+ PA  P G +  P   A    SP  
Sbjct: 471 P-------IELLPLGYSEPAFGPCF----SMPRGKPPAPSPRGQKASPPTLAPATASPPT 519

Query: 154 AAGTEGASPDLAPLRPAAPGQTPLRKEVLKSKMGKS 189
            AG+   +P L  L  AA  +  L   ++ S + +S
Sbjct: 520 TAGSN--NPCLTQLLTAAKPEQALEPPLVSSTLLRS 553



 Score = 38.5 bits (88), Expect = 0.008
 Identities = 45/173 (26%), Positives = 58/173 (33%), Gaps = 39/173 (22%)

Query: 2   TVVSVPQREPLVLGGRLAPLGFSSRGYFGALPMVTTAPPPLPRIPDPRALPPTL-----F 56
           T  SVP   P      L PLG+S    FG    +    PP P     +A PPTL      
Sbjct: 458 TPQSVPSPAPTPFPIELLPLGYSEPA-FGPCFSMPRGKPPAPSPRGQKASPPTLAPATAS 516

Query: 57  LPHFLGGDGPCLT-------PQPRAPAALPNRSLAVAGGTPRAAPKKRRKKKVRASPAGQ 109
            P   G + PCLT       P+      L + +L  + G+P        ++ V   P   
Sbjct: 517 PPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSP--------QETVPEFPCTF 568

Query: 110 LPSRFHQYQQHRPSLEGGRSPATGPSGAQEVPGPAAALAPSPAAAAGTEGASP 162
           LP                  P   P+  +  PGPA      P      E  SP
Sbjct: 569 LP------------------PTPAPTPPRPPPGPATLAPSRPLLVPKAERLSP 603


>gi|194733742 Wolf-Hirschhorn syndrome candidate 2 protein [Homo
           sapiens]
          Length = 539

 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 32/118 (27%), Positives = 48/118 (40%), Gaps = 8/118 (6%)

Query: 66  PCLTPQPRAPAALPNRSLAVAGGTPRAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLE 125
           P  +  P  P+ +P  S   +  TP  AP  R   +    P+   P+   Q++Q  P   
Sbjct: 331 PSTSYLPSTPSVVPASSYIPSSETP-PAPSSREASRPPEEPSAPSPTLPAQFKQRAPMYN 389

Query: 126 GGRSPATGPSGAQEVPGPAAALAPSPAAAAGTEGASPDLAPLRP--AAPGQTPLRKEV 181
            G SPAT    A     P + L P+   A      +P +A + P   AP Q   +K +
Sbjct: 390 SGLSPATPTPAA-----PTSPLTPTTPPAVAPTTQTPPVAMVAPQTQAPAQQQPKKNL 442


>gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens]
          Length = 987

 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 49/179 (27%), Positives = 68/179 (37%), Gaps = 34/179 (18%)

Query: 32  LPMVTTAPPP--------------LPRIPDPRALPPTLFLPHFLGGDGPCLTPQPRAPAA 77
           LP   TA PP              L ++  P +LPP    P   G         P+ P+ 
Sbjct: 312 LPAAATASPPTSLLAPSTNPLLESLKKMQTPPSLPPC---PESAGAATTEALSPPKTPSL 368

Query: 78  LPNRSLAVAGGTPRAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATGPS-G 136
           LP   L+ +G  P   P      K   +  G +P+         PS+         P+  
Sbjct: 369 LPPLGLSQSG-PPGLLPSPSFDSKPPTTLLGLIPA---------PSMVPATDTKAPPTLQ 418

Query: 137 AQEVPGPAAALAPSPAAAA----GTEGASPDLAPLRPAAPGQTPLRKEVLKSKMGKSEK 191
           A+    P A  APSPA       GT+  SP  +P  PAA   +P+ K +  +   KSEK
Sbjct: 419 AETATKPQATSAPSPAPKQSFLFGTQNTSPS-SPAAPAASSASPMFKPIFTAP-PKSEK 475


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 44/162 (27%), Positives = 57/162 (35%), Gaps = 7/162 (4%)

Query: 39  PPPLPRIPDP-RALPPTLFLPHFLGGDGPCLTPQPRAPAALPNRSLAVAGGTPRAAPKKR 97
           PPP+P  P P ++ P     P   GG     +P P  P    NR  A+ GG+ R +P   
Sbjct: 184 PPPVPSTPRPIQSSPHNRGSPPVPGGPRQP-SPGPTPPPFPGNRGTALGGGSIRQSPLSS 242

Query: 98  RKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATGPSGAQEVPGPAAALAPSPAAAAGT 157
                   P    PSR    +   P    G  P+     A   P P     P P+    +
Sbjct: 243 SSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHRE-AVPPPPPQNNKPPVPSTPRPS 301

Query: 158 EGASPDLAPLRPAAPGQTPLRKEVLKSKMGKSEKIALPHGQL 199
             +     P  P+ PG  PL      S  G  E   LP   L
Sbjct: 302 ASSQAPPPPPPPSRPGPPPLP----PSSSGNDETPRLPQRNL 339



 Score = 35.8 bits (81), Expect = 0.053
 Identities = 40/149 (26%), Positives = 51/149 (34%), Gaps = 38/149 (25%)

Query: 39  PPPLPRIPDPRALPPTLFLPHFLGGDGPCLTPQPRAPAALPNRSLAVAGGTPRAA----- 93
           PPP P  P P  LPP+          G   TP+      LP R+L+++  TP        
Sbjct: 309 PPPPPSRPGPPPLPPS--------SSGNDETPR------LPQRNLSLSSSTPPLPSPGRS 354

Query: 94  ------PKKRRKKKVRASP--AGQLP-----------SRFHQYQQHRPSLEGGRSPATGP 134
                 P +R    VR  P  +G LP           SR        PS  G  SP +GP
Sbjct: 355 GPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGP 414

Query: 135 SGAQEVPGPAAALAPSPAAAAGTEGASPD 163
                   P+A   P P  +        D
Sbjct: 415 RPPLPPDRPSAGAPPPPPPSTSIRNGFQD 443



 Score = 33.1 bits (74), Expect = 0.35
 Identities = 31/91 (34%), Positives = 38/91 (41%), Gaps = 11/91 (12%)

Query: 27  GYFGALPMVTTAPPPLPRIPDP-RALPPTLFLPHFLGGDGPCLTPQPRAPAALPNRSLAV 85
           G  G LP     PPP+ R     RALP T  LP   G D P   P+P  P   P+     
Sbjct: 374 GRSGPLP----PPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPS----- 424

Query: 86  AGGTPRAAPKKRRKKKVRASPA-GQLPSRFH 115
           AG  P   P    +   + SP   +  SRF+
Sbjct: 425 AGAPPPPPPSTSIRNGFQDSPCEDEWESRFY 455


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 44/162 (27%), Positives = 57/162 (35%), Gaps = 7/162 (4%)

Query: 39  PPPLPRIPDP-RALPPTLFLPHFLGGDGPCLTPQPRAPAALPNRSLAVAGGTPRAAPKKR 97
           PPP+P  P P ++ P     P   GG     +P P  P    NR  A+ GG+ R +P   
Sbjct: 184 PPPVPSTPRPIQSSPHNRGSPPVPGGPRQP-SPGPTPPPFPGNRGTALGGGSIRQSPLSS 242

Query: 98  RKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATGPSGAQEVPGPAAALAPSPAAAAGT 157
                   P    PSR    +   P    G  P+     A   P P     P P+    +
Sbjct: 243 SSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHRE-AVPPPPPQNNKPPVPSTPRPS 301

Query: 158 EGASPDLAPLRPAAPGQTPLRKEVLKSKMGKSEKIALPHGQL 199
             +     P  P+ PG  PL      S  G  E   LP   L
Sbjct: 302 ASSQAPPPPPPPSRPGPPPLP----PSSSGNDETPRLPQRNL 339



 Score = 35.8 bits (81), Expect = 0.053
 Identities = 40/149 (26%), Positives = 51/149 (34%), Gaps = 38/149 (25%)

Query: 39  PPPLPRIPDPRALPPTLFLPHFLGGDGPCLTPQPRAPAALPNRSLAVAGGTPRAA----- 93
           PPP P  P P  LPP+          G   TP+      LP R+L+++  TP        
Sbjct: 309 PPPPPSRPGPPPLPPS--------SSGNDETPR------LPQRNLSLSSSTPPLPSPGRS 354

Query: 94  ------PKKRRKKKVRASP--AGQLP-----------SRFHQYQQHRPSLEGGRSPATGP 134
                 P +R    VR  P  +G LP           SR        PS  G  SP +GP
Sbjct: 355 GPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGP 414

Query: 135 SGAQEVPGPAAALAPSPAAAAGTEGASPD 163
                   P+A   P P  +        D
Sbjct: 415 RPPLPPDRPSAGAPPPPPPSTSIRNGFQD 443



 Score = 33.1 bits (74), Expect = 0.35
 Identities = 31/91 (34%), Positives = 38/91 (41%), Gaps = 11/91 (12%)

Query: 27  GYFGALPMVTTAPPPLPRIPDP-RALPPTLFLPHFLGGDGPCLTPQPRAPAALPNRSLAV 85
           G  G LP     PPP+ R     RALP T  LP   G D P   P+P  P   P+     
Sbjct: 374 GRSGPLP----PPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPS----- 424

Query: 86  AGGTPRAAPKKRRKKKVRASPA-GQLPSRFH 115
           AG  P   P    +   + SP   +  SRF+
Sbjct: 425 AGAPPPPPPSTSIRNGFQDSPCEDEWESRFY 455


>gi|116256363 transmembrane protease, serine 13 [Homo sapiens]
          Length = 567

 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 31/112 (27%), Positives = 48/112 (42%)

Query: 73  RAPAALPNRSLAVAGGTPRAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPAT 132
           R P+A  + + A   GTP       +    +ASPAG  P R    Q        GR+   
Sbjct: 13  RTPSAGASPAQASPAGTPPGRASPAQASPAQASPAGTPPGRASPAQASPAGTPPGRASPG 72

Query: 133 GPSGAQEVPGPAAALAPSPAAAAGTEGASPDLAPLRPAAPGQTPLRKEVLKS 184
             S AQ  P  A+    SPA A+ +  +S   +  R A+   +P R  ++++
Sbjct: 73  RASPAQASPAQASPARASPALASLSRSSSGRSSSARSASVTTSPTRVYLVRA 124


>gi|145309322 insulinoma-associated protein IA-6 [Homo sapiens]
          Length = 566

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 34/100 (34%), Positives = 42/100 (42%), Gaps = 14/100 (14%)

Query: 66  PCLTPQPRAPAALPNRSLAVAGGTPRAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLE 125
           P L PQ  AP  L     A   G  RA P  R +      P   L +   + Q   P   
Sbjct: 27  PLLGPQG-APPFLEEAPSASLPGAERATPPTREE------PGKGLTAEAAREQSGSPCRA 79

Query: 126 GGRSPATGP-------SGAQEVPGPAAALAPSPAAAAGTE 158
            G SP TG        +G +E PGP+ + +PSPA  AG E
Sbjct: 80  AGVSPGTGGREGAEWRAGGREGPGPSPSPSPSPAKPAGAE 119



 Score = 30.0 bits (66), Expect = 2.9
 Identities = 53/168 (31%), Positives = 66/168 (39%), Gaps = 26/168 (15%)

Query: 17  RLAPLGFSSRGYFGALPMVTTAPPP-LPRIPDPRALPPTLFLPHFLGGDGPCLTPQP-RA 74
           RLA   F   G  GA P +  AP   LP     RA PPT   P      G  LT +  R 
Sbjct: 20  RLAERVFPLLGPQGAPPFLEEAPSASLPGAE--RATPPTREEP------GKGLTAEAARE 71

Query: 75  PAALPNRSLAVAGGTP-------RAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGG 127
            +  P R+  V+ GT        RA  ++        SP+   P++    +  R  LE  
Sbjct: 72  QSGSPCRAAGVSPGTGGREGAEWRAGGREGPGPSPSPSPS---PAKPAGAELRRAFLERC 128

Query: 128 RSPATGPSGAQEVPGPAAALAP---SPAAAAGTEGASPDLAPLRPAAP 172
            S    P  A+  PG AAA+A    S A AA        L PLR   P
Sbjct: 129 LS---SPVSAESFPGGAAAVAAFSCSVAPAAAPTPGEQFLLPLRAPFP 173


>gi|148237270 hypermethylated in cancer 1 isoform 2 [Homo sapiens]
          Length = 733

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 43/165 (26%), Positives = 63/165 (38%), Gaps = 14/165 (8%)

Query: 15  GGRLAPLGFSSRGYFGALPMVTTA-PPPLPRIPDPRALPPTLFLPHFLGGDGPCLTPQPR 73
           GG  AP G   RG   A P++    P P+   P P A PP+       G +    T    
Sbjct: 165 GGGYAPYGRPGRGLRAATPVIQACYPSPVGPPPPPAAEPPS-------GPEAAVNTHCAE 217

Query: 74  APAALPNRSLAVAGGTPRAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATG 133
             A+ P  + A+     R +P        ++ P    P R    ++  P  +    P+ G
Sbjct: 218 LYASGPGPAAALCASERRCSPLCGLDLSKKSPPGSAAPERPLAERELPPRPDS--PPSAG 275

Query: 134 PSGAQEVPGPAAALAPSPAAAAGTEGASPDLAPLR--PAAPGQTP 176
           P+  +E P    +L P P      E A+P   P R    +PG  P
Sbjct: 276 PAAYKEPPLALPSLPPLPFQK--LEEAAPPSDPFRGGSGSPGPEP 318


>gi|61676186 hypermethylated in cancer 1 isoform 1 [Homo sapiens]
          Length = 714

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 43/165 (26%), Positives = 63/165 (38%), Gaps = 14/165 (8%)

Query: 15  GGRLAPLGFSSRGYFGALPMVTTA-PPPLPRIPDPRALPPTLFLPHFLGGDGPCLTPQPR 73
           GG  AP G   RG   A P++    P P+   P P A PP+       G +    T    
Sbjct: 146 GGGYAPYGRPGRGLRAATPVIQACYPSPVGPPPPPAAEPPS-------GPEAAVNTHCAE 198

Query: 74  APAALPNRSLAVAGGTPRAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATG 133
             A+ P  + A+     R +P        ++ P    P R    ++  P  +    P+ G
Sbjct: 199 LYASGPGPAAALCASERRCSPLCGLDLSKKSPPGSAAPERPLAERELPPRPDS--PPSAG 256

Query: 134 PSGAQEVPGPAAALAPSPAAAAGTEGASPDLAPLR--PAAPGQTP 176
           P+  +E P    +L P P      E A+P   P R    +PG  P
Sbjct: 257 PAAYKEPPLALPSLPPLPFQK--LEEAAPPSDPFRGGSGSPGPEP 299


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.130    0.388 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,427,244
Number of Sequences: 37866
Number of extensions: 1068989
Number of successful extensions: 9751
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 111
Number of HSP's successfully gapped in prelim test: 898
Number of HSP's that attempted gapping in prelim test: 7294
Number of HSP's gapped (non-prelim): 2902
length of query: 327
length of database: 18,247,518
effective HSP length: 103
effective length of query: 224
effective length of database: 14,347,320
effective search space: 3213799680
effective search space used: 3213799680
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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