BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|5802982 proline-rich nuclear receptor coactivator 1 [Homo sapiens] (327 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|5802982 proline-rich nuclear receptor coactivator 1 [Homo sap... 664 0.0 gi|169161132 PREDICTED: hypothetical protein LOC100131261 [Homo ... 89 4e-18 gi|169160897 PREDICTED: similar to hCG1728885 [Homo sapiens] 87 2e-17 gi|169162148 PREDICTED: similar to hCG1728885 [Homo sapiens] 87 2e-17 gi|8923295 proline-rich nuclear receptor coactivator 2 [Homo sap... 86 6e-17 gi|188536004 zinc finger protein 469 [Homo sapiens] 49 6e-06 gi|92859678 small nuclear RNA activating complex, polypeptide 4,... 48 1e-05 gi|171543895 ataxin 2 [Homo sapiens] 46 4e-05 gi|110832843 TBP-associated factor 4 [Homo sapiens] 45 9e-05 gi|163965366 nascent polypeptide-associated complex alpha subuni... 45 9e-05 gi|16950645 neurotrophic factor artemin isoform 2 [Homo sapiens] 45 1e-04 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 44 2e-04 gi|9945318 MAX binding protein [Homo sapiens] 44 2e-04 gi|42475970 synapse defective 1, Rho GTPase, homolog 1 [Homo sap... 44 2e-04 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 44 2e-04 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 44 2e-04 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 43 3e-04 gi|239743660 PREDICTED: hypothetical protein XP_002342926 [Homo ... 43 4e-04 gi|14602439 Williams Beuren syndrome chromosome region 14 isofor... 42 6e-04 gi|14602437 Williams Beuren syndrome chromosome region 14 isofor... 42 6e-04 gi|14602435 Williams Beuren syndrome chromosome region 14 isofor... 42 6e-04 gi|14602433 Williams Beuren syndrome chromosome region 14 isofor... 42 6e-04 gi|194733742 Wolf-Hirschhorn syndrome candidate 2 protein [Homo ... 42 6e-04 gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens] 42 6e-04 gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 42 7e-04 gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 42 7e-04 gi|116256363 transmembrane protease, serine 13 [Homo sapiens] 42 7e-04 gi|145309322 insulinoma-associated protein IA-6 [Homo sapiens] 42 0.001 gi|148237270 hypermethylated in cancer 1 isoform 2 [Homo sapiens] 42 0.001 gi|61676186 hypermethylated in cancer 1 isoform 1 [Homo sapiens] 42 0.001 >gi|5802982 proline-rich nuclear receptor coactivator 1 [Homo sapiens] Length = 327 Score = 664 bits (1713), Expect = 0.0 Identities = 327/327 (100%), Positives = 327/327 (100%) Query: 1 MTVVSVPQREPLVLGGRLAPLGFSSRGYFGALPMVTTAPPPLPRIPDPRALPPTLFLPHF 60 MTVVSVPQREPLVLGGRLAPLGFSSRGYFGALPMVTTAPPPLPRIPDPRALPPTLFLPHF Sbjct: 1 MTVVSVPQREPLVLGGRLAPLGFSSRGYFGALPMVTTAPPPLPRIPDPRALPPTLFLPHF 60 Query: 61 LGGDGPCLTPQPRAPAALPNRSLAVAGGTPRAAPKKRRKKKVRASPAGQLPSRFHQYQQH 120 LGGDGPCLTPQPRAPAALPNRSLAVAGGTPRAAPKKRRKKKVRASPAGQLPSRFHQYQQH Sbjct: 61 LGGDGPCLTPQPRAPAALPNRSLAVAGGTPRAAPKKRRKKKVRASPAGQLPSRFHQYQQH 120 Query: 121 RPSLEGGRSPATGPSGAQEVPGPAAALAPSPAAAAGTEGASPDLAPLRPAAPGQTPLRKE 180 RPSLEGGRSPATGPSGAQEVPGPAAALAPSPAAAAGTEGASPDLAPLRPAAPGQTPLRKE Sbjct: 121 RPSLEGGRSPATGPSGAQEVPGPAAALAPSPAAAAGTEGASPDLAPLRPAAPGQTPLRKE 180 Query: 181 VLKSKMGKSEKIALPHGQLVHGIHLYEQPKINRQKSKYNLPLTKITSAKRNENNFWQDSV 240 VLKSKMGKSEKIALPHGQLVHGIHLYEQPKINRQKSKYNLPLTKITSAKRNENNFWQDSV Sbjct: 181 VLKSKMGKSEKIALPHGQLVHGIHLYEQPKINRQKSKYNLPLTKITSAKRNENNFWQDSV 240 Query: 241 SSDRIQKQEKKPFKNTENIKNSHLKKSAFLTEVSQKENYAGAKFSDPPSPSVLPKPPSHW 300 SSDRIQKQEKKPFKNTENIKNSHLKKSAFLTEVSQKENYAGAKFSDPPSPSVLPKPPSHW Sbjct: 241 SSDRIQKQEKKPFKNTENIKNSHLKKSAFLTEVSQKENYAGAKFSDPPSPSVLPKPPSHW 300 Query: 301 MGSTVENSNQNRELMAVHLKTLLKVQT 327 MGSTVENSNQNRELMAVHLKTLLKVQT Sbjct: 301 MGSTVENSNQNRELMAVHLKTLLKVQT 327 >gi|169161132 PREDICTED: hypothetical protein LOC100131261 [Homo sapiens] Length = 139 Score = 89.4 bits (220), Expect = 4e-18 Identities = 52/121 (42%), Positives = 72/121 (59%), Gaps = 5/121 (4%) Query: 208 QPKINRQKSKYNLPLTKITSAKRNENNFWQDSVSSDRIQKQ--EKKPFKNTENIKNSHLK 265 Q ++NRQK+K KI K+ + + S + + K + K F N ++ NS L Sbjct: 21 QQQLNRQKTKEQNSQMKIVHKKKERGHGYNSSAGAWQAMKNGGKNKNFPNNQSW-NSSLS 79 Query: 266 KSAFLTEVSQKENYAGAKFSDPPSPSVLPKPPSHWMGSTVENSNQNRELMAVHLKTLLKV 325 + L + K+NYAGAKFS+PPSPSVLPKPPSHW+ V + ++E+M LKTLLKV Sbjct: 80 GPSLLFKSQAKQNYAGAKFSEPPSPSVLPKPPSHWV--PVSFNPSDKEIMTFQLKTLLKV 137 Query: 326 Q 326 Q Sbjct: 138 Q 138 >gi|169160897 PREDICTED: similar to hCG1728885 [Homo sapiens] Length = 139 Score = 87.4 bits (215), Expect = 2e-17 Identities = 51/121 (42%), Positives = 71/121 (58%), Gaps = 5/121 (4%) Query: 208 QPKINRQKSKYNLPLTKITSAKRNENNFWQDSVSSDRIQKQ--EKKPFKNTENIKNSHLK 265 Q ++NRQK+K KI K+ + + S + + K + K F N ++ NS L Sbjct: 21 QQQLNRQKTKEQNSQMKIVHKKKERGHGYNSSAGAWQAMKNGGKNKNFPNNQSW-NSSLS 79 Query: 266 KSAFLTEVSQKENYAGAKFSDPPSPSVLPKPPSHWMGSTVENSNQNRELMAVHLKTLLKV 325 + L + +NYAGAKFS+PPSPSVLPKPPSHW+ V + ++E+M LKTLLKV Sbjct: 80 GPSLLFKSQANQNYAGAKFSEPPSPSVLPKPPSHWV--PVSFNPSDKEIMTFQLKTLLKV 137 Query: 326 Q 326 Q Sbjct: 138 Q 138 >gi|169162148 PREDICTED: similar to hCG1728885 [Homo sapiens] Length = 139 Score = 87.4 bits (215), Expect = 2e-17 Identities = 51/121 (42%), Positives = 71/121 (58%), Gaps = 5/121 (4%) Query: 208 QPKINRQKSKYNLPLTKITSAKRNENNFWQDSVSSDRIQKQ--EKKPFKNTENIKNSHLK 265 Q ++NRQK+K KI K+ + + S + + K + K F N ++ NS L Sbjct: 21 QQQLNRQKTKEQNSQMKIVHKKKERGHGYNSSAGAWQAMKNGGKNKNFPNNQSW-NSSLS 79 Query: 266 KSAFLTEVSQKENYAGAKFSDPPSPSVLPKPPSHWMGSTVENSNQNRELMAVHLKTLLKV 325 + L + +NYAGAKFS+PPSPSVLPKPPSHW+ V + ++E+M LKTLLKV Sbjct: 80 GPSLLFKSQANQNYAGAKFSEPPSPSVLPKPPSHWV--PVSFNPSDKEIMTFQLKTLLKV 137 Query: 326 Q 326 Q Sbjct: 138 Q 138 >gi|8923295 proline-rich nuclear receptor coactivator 2 [Homo sapiens] Length = 139 Score = 85.5 bits (210), Expect = 6e-17 Identities = 50/121 (41%), Positives = 71/121 (58%), Gaps = 5/121 (4%) Query: 208 QPKINRQKSKYNLPLTKITSAKRNENNFWQDSVSSDRIQKQ--EKKPFKNTENIKNSHLK 265 Q ++NRQK+K KI K+ + + S ++ + + + K F N ++ NS L Sbjct: 21 QQQLNRQKTKEQNSQMKIVHKKKERGHGYNSSAAAWQAMQNGGKNKNFPNNQSW-NSSLS 79 Query: 266 KSAFLTEVSQKENYAGAKFSDPPSPSVLPKPPSHWMGSTVENSNQNRELMAVHLKTLLKV 325 L + +NYAGAKFS+PPSPSVLPKPPSHW+ V + ++E+M LKTLLKV Sbjct: 80 GPRLLFKSQANQNYAGAKFSEPPSPSVLPKPPSHWV--PVSFNPSDKEIMTFQLKTLLKV 137 Query: 326 Q 326 Q Sbjct: 138 Q 138 >gi|188536004 zinc finger protein 469 [Homo sapiens] Length = 3925 Score = 48.9 bits (115), Expect = 6e-06 Identities = 43/136 (31%), Positives = 54/136 (39%), Gaps = 11/136 (8%) Query: 65 GPCLTPQPRAPAALPNRSLAVAGGTPRAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSL 124 GP +PQ R P+ RSL PK + V Q+P+ ++ RPSL Sbjct: 1136 GPGRSPQARGPS----RSLETGAAAREGGPKCADRPSVAPKDPLQVPTNTETSEETRPSL 1191 Query: 125 E---GGRSPATGPSGAQEVPGPAAALAPSPAAAAGTEGASPDLAPLRPAAPGQTPLRKEV 181 + + P T A + AL PAA AG GASP L L P P P R + Sbjct: 1192 DFPQEAKEPETAEESAPDSTEFTEALRSPPAACAGEMGASPGL--LIPEQP--PPSRHDT 1247 Query: 182 LKSKMGKSEKIALPHG 197 K S PHG Sbjct: 1248 GTPKPSGSLANTAPHG 1263 >gi|92859678 small nuclear RNA activating complex, polypeptide 4, 190kDa [Homo sapiens] Length = 1469 Score = 47.8 bits (112), Expect = 1e-05 Identities = 39/138 (28%), Positives = 55/138 (39%), Gaps = 15/138 (10%) Query: 40 PPLPRIPDPRALPPTLFLPHFLGGDGPCLTPQPRAPAALPNRSLAVAGGTPRAAPKKRRK 99 PPLP P R P GP + P + P + G+ + A + Sbjct: 931 PPLPHTPHGRPAP------------GPTVLNVPLSGPGAPAAAKPGTSGSWQEAGTSAKD 978 Query: 100 KKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATGPSGAQEVPGPAAALAPSPAAAAGTEG 159 K++ A L F + + P+ ++PA GP G V P + L S A AA + Sbjct: 979 KRLSTMQALPLAPVFSEAEGTAPA--ASQAPALGP-GQISVSCPESGLGQSQAPAASRKQ 1035 Query: 160 ASPDLAPLRPAAPGQTPL 177 P+ P PAAP TPL Sbjct: 1036 GLPEAPPFLPAAPSPTPL 1053 Score = 28.9 bits (63), Expect = 6.5 Identities = 19/53 (35%), Positives = 31/53 (58%), Gaps = 3/53 (5%) Query: 122 PSLEGGRSPATGPSGAQEVPGPAAALAPSPAAAAGTEGASPDLAPLRPAAPGQ 174 P+ + P G +GA + GPAA+L+P P ++ ++G S + A AAPG+ Sbjct: 574 PARQSTSQPWRGGAGAW-LGGPAASLSP-PKGSSASQGGSKE-ASTTAAAPGE 623 Score = 28.9 bits (63), Expect = 6.5 Identities = 48/170 (28%), Positives = 63/170 (37%), Gaps = 18/170 (10%) Query: 14 LGGRLAPLGFSSRGYFGALPMVTTAPPPLPRIPDPRALPPTLFLPHFLGGDGP-----CL 68 LG AP +G A P + AP P P P +L + PH + P L Sbjct: 1023 LGQSQAPAASRKQGLPEAPPFLPAAPSPTPLPVQPLSL-THIGGPH-VATSVPLPVTWVL 1080 Query: 69 TPQPRAPAALPN-RSLAVAGGTPRAAPKKRR----KKKVRASPAGQLPSRFHQYQQHRPS 123 T Q P +P SL GTP A + RA+ + P+ +Q P Sbjct: 1081 TAQGLLPVPVPAVVSLPRPAGTPGPAGLLATLLPPLTETRAAQGPRAPALSSSWQ---PP 1137 Query: 124 LEGGRSPATGPSGAQEVPGPAA-ALAPSPAAAAGTEGASPDLAPLRPAAP 172 R P PS + P P AL+ SPA A G+ P A + P Sbjct: 1138 ANMNREPE--PSCRTDTPAPPTHALSQSPAEADGSVAFVPGEAQVAREIP 1185 >gi|171543895 ataxin 2 [Homo sapiens] Length = 1313 Score = 46.2 bits (108), Expect = 4e-05 Identities = 79/331 (23%), Positives = 116/331 (35%), Gaps = 60/331 (18%) Query: 22 GFSSRGYFGALPMVTTAPPPLPRIPD-----PRALPPTLFLPHFLGGDGPCLTPQPRAPA 76 G R G +P + P P R P P +LPP P T P P Sbjct: 540 GSDQRVVNGGVPWPSPCPSPSSRPPSRYQSGPNSLPPRAATP----------TRPPSRPP 589 Query: 77 ALPNR--SLAVAGGTPRAAPKKRRKKKV------RASPAGQLPSRFHQYQQHRPSLEGGR 128 + P+R S A G+P AP K++ R SP Q R H+ R S+ G Sbjct: 590 SRPSRPPSHPSAHGSP--APVSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGL 647 Query: 129 SPATGPSGAQEVPGPAAALAPSPAAAAGTEGASPDLAPL--RPAAP-----GQTPLRKEV 181 + ++ P A +PS + P L+P RP +P G TP + Sbjct: 648 EFVSHNPPSEAATPPVARTSPSGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVL 707 Query: 182 LKSKMG--KSEKIALP------------------HGQLVHGIHLYEQPKINRQKSKYNL- 220 + G +E +A+P L +Q + + +K N+ Sbjct: 708 ASPQAGIIPTEAVAMPIPAASPTPASPASNRAVTPSSEAKDSRLQDQRQNSPAGNKENIK 767 Query: 221 PLTKITSAKRNENNFWQDSVSSDRIQKQEKKPFKNTENIKNSHLKKSAFLTEVSQKENYA 280 P S + EN VS R Q + K FKN ++ S +S + +N Sbjct: 768 PNETSPSFSKAENKGISPVVSEHRKQIDDLKKFKNDFRLQPSSTSES---MDQLLNKNRE 824 Query: 281 GAKFSDPPSPSVLPKPPSHWMGSTVENSNQN 311 G K D + P S +ENS+ N Sbjct: 825 GEKSRDLIKDKIEPSAKD----SFIENSSSN 851 Score = 40.4 bits (93), Expect = 0.002 Identities = 51/220 (23%), Positives = 89/220 (40%), Gaps = 37/220 (16%) Query: 84 AVAGGTPRAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATGPSGAQEVPGP 143 +V G PR +PK R + R + G PS P L SP G + V P Sbjct: 675 SVVSGVPRLSPKTHRPRSPRQNSIGNTPS--------GPVL---ASPQAGIIPTEAVAMP 723 Query: 144 AAALAPSPAAAAGTEGASPDLAPLRPAAPGQTPLRKEVLKSKMGKSEKIALPHGQLVHGI 203 A +P+PA+ A +P + + L+ + S G E I P+ Sbjct: 724 IPAASPTPASPASNRAVTPS------SEAKDSRLQDQRQNSPAGNKENIK-PN------- 769 Query: 204 HLYEQPKINRQKSKYNLPLT-----KITSAKRNENNF----WQDSVSSDRIQKQEKKPFK 254 P ++ ++K P+ +I K+ +N+F S S D++ + ++ K Sbjct: 770 --ETSPSFSKAENKGISPVVSEHRKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEK 827 Query: 255 NTENIKNSHLKKSAFLTEVSQKENYAGAKFSDPPSPSVLP 294 + + IK+ ++ SA + + + + S P SPS+ P Sbjct: 828 SRDLIKDK-IEPSAKDSFIENSSSNCTSGSSKPNSPSISP 866 Score = 33.5 bits (75), Expect = 0.26 Identities = 68/289 (23%), Positives = 103/289 (35%), Gaps = 76/289 (26%) Query: 20 PLGFSSRGYFGALP--MVTTAPPPLPRIPDP--RALPPTL-------------FLP---H 59 P S RG GA P + APPP P P ++ PP+ F P Sbjct: 34 PARRSGRGGGGAAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFRPGSRR 93 Query: 60 FLGGDGP------CLTP--QPRAPAALPNRSLAV----------------AGGTPRAAP- 94 LG GP L P P AP A P R+ + A G PR A Sbjct: 94 LLGLGGPPRPFVVLLLPLASPGAPPAAPTRASPLGARASPPRSGVSLARPAPGCPRPACE 153 Query: 95 ----------KKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGR---------SPATGPS 135 K +++++ + Q + Q QQ P+ R SPA PS Sbjct: 154 PVYGPLTMSLKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPS 213 Query: 136 GAQEVPGPAAALAPSPAAAAGTEGASPDLAPLRPAAPG--QTPLRKE----------VLK 183 + ++A APS AA + G P L R + G Q+ + + +L Sbjct: 214 PSSSSVSSSSATAPSSVVAATSGGGRPGLGRGRNSNKGLPQSTISFDGIYANMRMVHILT 273 Query: 184 SKMGKSEKIALPHGQLVHGIHLYEQPKINRQKSKYNLPLTKITSAKRNE 232 S +G ++ + +G + G+ PK + + T+ +S + E Sbjct: 274 SVVGSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHEKSTESSSGPKRE 322 >gi|110832843 TBP-associated factor 4 [Homo sapiens] Length = 1085 Score = 45.1 bits (105), Expect = 9e-05 Identities = 45/159 (28%), Positives = 60/159 (37%), Gaps = 17/159 (10%) Query: 31 ALPMVTTAPPPLPRIPDPRALPPTLFLPHFLGGDGPCLTPQPRAPAALPNRSLAVAGGTP 90 A+ +V P L +P P A + P F+G P P PAA + A A P Sbjct: 214 AVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPP 273 Query: 91 RAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPAT--------GPSGAQEVPG 142 AP + PAG P+ + GG + A GP+G PG Sbjct: 274 PPAPATLARPP--GHPAGP-PTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPG 330 Query: 143 P-AAALAPSPAAAAGT-----EGASPDLAPLRPAAPGQT 175 P AAA AP+P A + + A P L + P T Sbjct: 331 PGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPAST 369 Score = 40.0 bits (92), Expect = 0.003 Identities = 43/157 (27%), Positives = 51/157 (32%), Gaps = 34/157 (21%) Query: 43 PRIPDPRALPPTLFLPHFLGGD-------GPCLTPQPRAPAALPN-----RSLAVAGGTP 90 PR P+ RA H + G GP P AP A P R+ GG Sbjct: 45 PRTPEVRAAAAGALGNHVVSGSPAGAAGAGPA-APAEGAPGAAPEPPPAGRARPGGGGPQ 103 Query: 91 RAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRS--------------PATGPSG 136 R P R+ V A PA RP EG P P+G Sbjct: 104 RPGPPSPRRPLVPAGPAPPAAKL-------RPPPEGSAGSCAPVPAAAAVAAGPEPAPAG 156 Query: 137 AQEVPGPAAALAPSPAAAAGTEGASPDLAPLRPAAPG 173 + GPAA A + G P P +PA PG Sbjct: 157 PAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPG 193 Score = 34.3 bits (77), Expect = 0.16 Identities = 57/188 (30%), Positives = 65/188 (34%), Gaps = 34/188 (18%) Query: 9 REPLVLGG------RLAPLGFSSRGYFGALPM---VTTAPPPLPRIPDPRALPPTLFLPH 59 R PLV G +L P S G +P V P P P P A P L Sbjct: 111 RRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARA 170 Query: 60 FLG---GDGPCLTPQPRAPAA-----LPNRSLAVAGGTPRAAPKKRRKKKVRASPAGQLP 111 G G GP P P PA N S A+ AAP V PA LP Sbjct: 171 GPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAV---SLVNNGPAALLP 227 Query: 112 SRFHQYQQHRPSLEGGRSPATGPSGAQEVPGPAAA---LAPSPAAAAGTEGASPDLAPLR 168 +P+ G GA P PAA AP+PAA A A+P P Sbjct: 228 LP-------KPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPA----AAPPPPPPA 276 Query: 169 PAAPGQTP 176 PA + P Sbjct: 277 PATLARPP 284 Score = 32.7 bits (73), Expect = 0.45 Identities = 40/160 (25%), Positives = 45/160 (28%), Gaps = 38/160 (23%) Query: 33 PMVTTAPPPLPRIPDPRALPP----------------TLFLPHFLGGDGPCLTPQPRAPA 76 P V A PP P P P A P TL P P P PA Sbjct: 242 PFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPA 301 Query: 77 ALPNRSLAVAGGTPRAAPKKRRKKKVRASPA-------------GQLPSRFHQYQQHRPS 123 A N A G P AP V P + P R Q Sbjct: 302 AAQNGGSA--GAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQ 359 Query: 124 LEGGRSPAT-------GPSGAQEVPGPAAALAPSPAAAAG 156 PA+ GP+ +P PAA P+P G Sbjct: 360 TLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTG 399 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 45.1 bits (105), Expect = 9e-05 Identities = 49/148 (33%), Positives = 60/148 (40%), Gaps = 26/148 (17%) Query: 33 PMVTTAPPPL--PRIPDPRALP--PTLFLPHFLGGDGPCLTPQPRAPAALPNRSLAVAGG 88 P T P P P P P+ P P + P G P TP P+ + P + G Sbjct: 988 PPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGS--PAATPFPKGASTPPAATPPSPKG 1045 Query: 89 TPRAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATGPSGAQEVPGPAAALA 148 +P A P K +PA LPS +GG PAT PS + P P AA Sbjct: 1046 SPAATPLP---KGAPTTPAATLPSP-----------KGG--PAT-PS-LKGAPTPPAATP 1087 Query: 149 PSPAAAAGTEGASPDLAPLRPAAPGQTP 176 PSP T SP AP+ PAA +P Sbjct: 1088 PSPKGGPATP--SPKGAPMPPAATPPSP 1113 Score = 43.5 bits (101), Expect = 3e-04 Identities = 49/171 (28%), Positives = 63/171 (36%), Gaps = 23/171 (13%) Query: 33 PMVTTAPPPLPR----IPDPRALP--PTLFLPHFLGGDGPCLTPQPRAPAALPNRSLAVA 86 P A PP P+ P P+ P P P GG TP P+ P + Sbjct: 1195 PTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG---LATPSPKGAPTTPAATPPSP 1251 Query: 87 GGTPRAAPKKRRKKKVRASPA---GQLPSRFHQYQQHR-----PSLEGGRSPATGPSGAQ 138 G P P K A+P G L + H+ + PS +GG PAT P + Sbjct: 1252 KGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGG--PATSPP--K 1307 Query: 139 EVPGPAAALAPSPAAAAGTEG--ASPDLAPLRPAAPGQTPLRKEVLKSKMG 187 P P AA PSP + GT +P + P +P TP S G Sbjct: 1308 GAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKG 1358 Score = 39.7 bits (91), Expect = 0.004 Identities = 50/157 (31%), Positives = 62/157 (39%), Gaps = 23/157 (14%) Query: 33 PMVTTAP-PPLPR-IPDPRALPPT----LFLPHFLGGDGPCLTPQPRAPAALPNRSLAVA 86 P T +P PP P+ P P A+ P + LP P TP P LP A Sbjct: 850 PATTHSPTPPSPKGAPTPSAVTPLSPKGVTLP-------PKETPTPSV-VNLPFPKEGPA 901 Query: 87 GGTPRAAPK----KRRKKKVRASPAGQ-LPSRFHQYQQHRPSLEGGRSPATGPS--GAQE 139 P+ AP KK RA+PA + +P+ P SP GP+ + Sbjct: 902 TPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKW 961 Query: 140 VPGPAAALAPSPAAAAGTEGASPDLAPLRPAAPGQTP 176 P P AA PSP T SP AP PAA +P Sbjct: 962 APTPPAATPPSPKGGPATP--SPKGAPTPPAATPPSP 996 Score = 37.4 bits (85), Expect = 0.018 Identities = 39/142 (27%), Positives = 53/142 (37%), Gaps = 21/142 (14%) Query: 39 PPPLPRIPDPRALPPTL----FLPHFLGGDGPCLT--PQPRA-PAALPNRSL----AVAG 87 PPP P A PP+L P G P + P P+ PA P + A Sbjct: 1258 PPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATP 1317 Query: 88 GTPRAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATGPSGAQEVPGPAAAL 147 +P+ +P K PA PS + P+L PAT PS P++ Sbjct: 1318 PSPKGSPGTPPPKGAPTPPAVTPPS-----PKGTPTL-----PATTPSSKGGPTTPSSKE 1367 Query: 148 APSPAAAAGTEGASPDLAPLRP 169 P+P AA + P + P P Sbjct: 1368 GPTPPAATPSHKGGPAMTPPSP 1389 Score = 37.0 bits (84), Expect = 0.024 Identities = 43/147 (29%), Positives = 53/147 (36%), Gaps = 38/147 (25%) Query: 31 ALPMVTTAPPPLPRIPDPRALPPTLFLPHFLGGDGPCLTPQPRAPAALPNRSLAVAGGTP 90 AL M +++P P P+ +P + P P PAA P +P Sbjct: 910 ALSMTSSSPKKARATPAPKGIPAS-----------PSPKGAPTPPAATPP--------SP 950 Query: 91 RAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPAT-GPSGAQEVPGPAAALAP 149 + P K PA PS +GG PAT P GA P P AA P Sbjct: 951 KGGPATPSPKWAPTPPAATPPSP-----------KGG--PATPSPKGA---PTPPAATPP 994 Query: 150 SPAAAAGTEGASPDLAPLRPAAPGQTP 176 SP T SP AP PA +P Sbjct: 995 SPKGGPATP--SPKGAPTPPAVTPPSP 1019 Score = 37.0 bits (84), Expect = 0.024 Identities = 46/179 (25%), Positives = 59/179 (32%), Gaps = 20/179 (11%) Query: 24 SSRGYFGALPMVTTAPPPLPRIPDPRALPPT-LFLPHFLGGDG-PCLTPQPRAPAALPNR 81 S +G G P PP P P+ P P GG P P PAA P+ Sbjct: 1319 SPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSH 1378 Query: 82 SLAVAGGTPRAAPKKRRKKKVRASPAGQ--LPSRFHQYQQHRPSLEGGRSPATGPSGAQE 139 G P P ++ SP G P+ + P+ R A PS Sbjct: 1379 K-----GGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDL 1433 Query: 140 VPGPA----------AALAPSPAAAAGTEGASPDLAPLRPAAPGQTPLRKEVLKSKMGK 188 P PA A AP A + P L + P +P + P K+V S K Sbjct: 1434 TP-PAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPK 1491 Score = 31.6 bits (70), Expect = 1.0 Identities = 44/166 (26%), Positives = 64/166 (38%), Gaps = 33/166 (19%) Query: 34 MVTTAPPPLPRIPDPRALP--PTLFL-----PHFLGGDGPCLTPQPRAPAALPNRSLAVA 86 ++ ++P +P P R P PT L P L + P P+ P ++ A+ Sbjct: 1508 VIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPS--PKKTPAIP 1565 Query: 87 GGTPRAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATGPSGAQEVPGPAAA 146 TP+ AP K+ +SP PS + +G SP +E+ P A Sbjct: 1566 --TPKEAPATPSSKEA-SSPPAVTPSTY----------KGAPSP-------KELLIPPAV 1605 Query: 147 LAPSPAAA---AGTEGASPDLAPLRPAAPGQTPLRKEVLKSKMGKS 189 +PSP A SP+ P PA G TP V S + S Sbjct: 1606 TSPSPKEAPTPPAVTPPSPEKGPATPAPKG-TPTSPPVTPSSLKDS 1650 Score = 30.8 bits (68), Expect = 1.7 Identities = 39/147 (26%), Positives = 52/147 (35%), Gaps = 12/147 (8%) Query: 30 GALPMVTTAPPPLPRIPDPRALPPTLFLPHFLGGDGPCLTPQPRAPAALPNRSLAVAGGT 89 G P+V T P + P T P GP +P +PAAL +A + Sbjct: 437 GTTPLVVTNPCTIAAAPTTTFEVATCVSPPM--SSGPISNIEPTSPAALVMAPVAPKEPS 494 Query: 90 PRAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATGPSGAQEVPGPAAALAP 149 + A R + SP P ++ PS + P Q VP Sbjct: 495 TQVATTLR----IPVSPPLPDPEDL----KNLPSSVLVKFPTQ--KDLQTVPASLEGAPF 544 Query: 150 SPAAAAGTEGASPDLAPLRPAAPGQTP 176 SPA A T P + PL AAP +P Sbjct: 545 SPAQAGLTTKKDPTVLPLVQAAPKNSP 571 Score = 28.5 bits (62), Expect = 8.5 Identities = 20/56 (35%), Positives = 27/56 (48%), Gaps = 5/56 (8%) Query: 127 GRSPATGPSGAQEVPGPAAALAPSPAAAAGTEGAS-----PDLAPLRPAAPGQTPL 177 G + T P+ QE+P P A A P ++A + A+ P L P AP Q PL Sbjct: 3 GEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPL 58 >gi|16950645 neurotrophic factor artemin isoform 2 [Homo sapiens] Length = 237 Score = 44.7 bits (104), Expect = 1e-04 Identities = 50/175 (28%), Positives = 68/175 (38%), Gaps = 12/175 (6%) Query: 34 MVTTAPPPLPRIPDPRALPPTLFLPHFLGGDG--PCLTPQPRAPAALPNRSLAVAGGTPR 91 +++ PL + P+A LFLP G P L P A A L + + A G PR Sbjct: 4 LISARGQPLLEVLPPQAHLGALFLPEAPLGLSAQPALWPTLAALALLSSVAEASLGSAPR 63 Query: 92 AAPKKRRKKKVRASPAGQLP----SRFHQYQQHRPSLEGGRSPATGPSGAQEVP-GPAAA 146 + + V ASPAG LP +R+ + RP + R P+ +P G AA Sbjct: 64 SPAPREGPPPVLASPAGHLPGGRTARWCSGRARRPPPQPSRPAPPPPAPPSALPRGGRAA 123 Query: 147 LAPSP---AAAAGTEGA--SPDLAPLRPAAPGQTPLRKEVLKSKMGKSEKIALPH 196 A P A AAG G L P+R G + G + PH Sbjct: 124 RAGGPGSRARAAGARGCRLRSQLVPVRALGLGHRSDELVRFRFCSGSCRRARSPH 178 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 44.3 bits (103), Expect = 2e-04 Identities = 50/156 (32%), Positives = 56/156 (35%), Gaps = 23/156 (14%) Query: 33 PMVTTAPPPLPRIPDPRALPPTLFLPHFLGGD--GPCLTPQPRAPAALPNRSLAVAGGTP 90 PM +A PP P+ P P A PP P P TP PR P L L V P Sbjct: 715 PMSPSATPP-PQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPP 773 Query: 91 RAAPKKRRKKKVRASPAG----------QLPSRFHQYQQHRPSLEGGRSP-ATGPSGAQE 139 + P K +P P+ F PS SP AT P A Sbjct: 774 ASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPP 833 Query: 140 V-PGPAAALAPSPAAAAGTEGASPDL-APLRPAAPG 173 V P + PSP ASP L AP RP PG Sbjct: 834 VLAAPLLQVPPSPP-------ASPTLQAPRRPPTPG 862 Score = 41.6 bits (96), Expect = 0.001 Identities = 43/150 (28%), Positives = 57/150 (38%), Gaps = 15/150 (10%) Query: 35 VTTAPPPLPR---IPDPRALPPTLFLPHFLGGDGPCL----TPQPRAPAALPNRSLAVAG 87 +TT PP P P P+A PP L P G P L TP P+AP L L Sbjct: 576 LTTPPPETPSSIATPPPQA-PPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPP 634 Query: 88 GTPRAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATGPSGAQEVPGPAAAL 147 P + P A+P+ Q P+ + P P P P P + Sbjct: 635 SPPASPPLSPL-----ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP-PVSPS 688 Query: 148 APSPAAAAGTEGASP-DLAPLRPAAPGQTP 176 A P+ A + A P + P PA+P +P Sbjct: 689 ATPPSQAPPSLAAPPLQVPPSPPASPPMSP 718 Score = 38.5 bits (88), Expect = 0.008 Identities = 43/140 (30%), Positives = 54/140 (38%), Gaps = 21/140 (15%) Query: 31 ALPMVTTAPPPLPRIPDPRALPPTLFLPHFLGGDGPCLTPQPRAPAALPNRSLAVAGGTP 90 +LPM A PP P+ P A PP LP +P P P A +P Sbjct: 775 SLPMSPLAKPP-PQAPPALATPPLQALP----------SPPASFPGQAPFSPSASLPMSP 823 Query: 91 RAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPAT-GPSGAQEVPGPAAALAP 149 A P + V A+P Q+P P+L+ R P T GP + P ALAP Sbjct: 824 LATPPPQAPP-VLAAPLLQVPPS----PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP 878 Query: 150 SPAAAAGTEGAS----PDLA 165 P +S PDLA Sbjct: 879 GPPPPPSRSPSSTLSGPDLA 898 Score = 37.7 bits (86), Expect = 0.014 Identities = 42/145 (28%), Positives = 50/145 (34%), Gaps = 20/145 (13%) Query: 38 APPPLPRIPDPRALPPTLFLPHFLGGD--------GPCLTPQPRAPAALPNRSLAVAGGT 89 +PP P P PP+L P P TP P+AP L L V Sbjct: 682 SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSP 741 Query: 90 PRAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATGPSGAQEVPGPAA--AL 147 P + P SP+ P R P PA+ P P P A AL Sbjct: 742 PASPP---------MSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPAL 792 Query: 148 APSPAAAAGTEGAS-PDLAPLRPAA 171 A P A + AS P AP P+A Sbjct: 793 ATPPLQALPSPPASFPGQAPFSPSA 817 Score = 34.7 bits (78), Expect = 0.12 Identities = 54/190 (28%), Positives = 64/190 (33%), Gaps = 46/190 (24%) Query: 34 MVTTAPPPLPRIPDPRALPPTLF------------LPHFLGGDGPCLTPQPRAPAALPNR 81 ++T PP PR P P P L L GG G P+ AP A P R Sbjct: 24 LLTPRPPGSPR-PPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPES-APRAGPTR 81 Query: 82 SLAVAGGTP-----------RAAPKK-----------RRKKKVRASPAGQLPSRFHQYQQ 119 S + P RA P K R R P GQ R + Sbjct: 82 SAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEET 141 Query: 120 --HRPSLEGGRSPATGPSGAQEVPGPAAALAPSPAAA-----AGTEGASPDLAP-LRPAA 171 + E + A ++ GP PSPA A AGTE P AP RP Sbjct: 142 VARGKATEAPKRSALSAGARRDTSGPTPG-TPSPAMARRSRAAGTEVGLPRPAPSARPRP 200 Query: 172 PGQTPLRKEV 181 P + P RK V Sbjct: 201 PTEGP-RKSV 209 Score = 31.6 bits (70), Expect = 1.0 Identities = 36/142 (25%), Positives = 55/142 (38%), Gaps = 9/142 (6%) Query: 33 PMVTTAPPPLPRIPDPRA-----LPPTLFLPHFLGGDGPCLTPQPRAPAALPNRSLAVAG 87 P +APP L +P P A PP++ P P + P +L + SL A Sbjct: 345 PPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQ-AP 403 Query: 88 GTPRAAPKKRRKKKVRASPAGQLPSRF--HQYQQHRPSLEGGRSPATGPSGAQEVPGPAA 145 +P A + + SP Q F +Q + SL PA+ P + + P + Sbjct: 404 PSPLALSSLQATTSL-GSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLS 462 Query: 146 ALAPSPAAAAGTEGASPDLAPL 167 A P + + SP +PL Sbjct: 463 LPASPPLQTSLSPAVSPLSSPL 484 Score = 30.8 bits (68), Expect = 1.7 Identities = 30/103 (29%), Positives = 40/103 (38%), Gaps = 9/103 (8%) Query: 75 PAALPNRSLAVAGGTPRAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATGP 134 P + P RS A GTPRA + K P G R Q R +PA GP Sbjct: 248 PLSSPARSGPSARGTPRAPAHPSQPK-----PKGLQALRPPQVTPPRKDA----APALGP 298 Query: 135 SGAQEVPGPAAALAPSPAAAAGTEGASPDLAPLRPAAPGQTPL 177 + + P+ + + A+P A L P+ P TPL Sbjct: 299 LSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPL 341 Score = 30.8 bits (68), Expect = 1.7 Identities = 53/176 (30%), Positives = 72/176 (40%), Gaps = 35/176 (19%) Query: 27 GYFGALPMVTTAPP-----PLPRIPDPRALPPTLFLPHFLGGDGPCLTPQPRA---PAAL 78 G + P+ T +P P+P PD A P LP L P TP P A P+A Sbjct: 297 GPLSSSPLATPSPSGTKARPVPP-PDNAATP----LPATLPPSPPLATPLPLAPPSPSAP 351 Query: 79 PN-RSLAVAGGTPRA-APKKRRKKKVRASPAGQ-LPSRFHQYQQHRPSLEGGRSP----- 130 P+ ++L TP + AP ++A P+ Q +P + PSL+ SP Sbjct: 352 PSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSS 411 Query: 131 --ATGPSGAQEV----------PGPAAALAPSPAAAAGTEGASPDL-APLR-PAAP 172 AT G+ + P A SP+ A T SP L APL PA+P Sbjct: 412 LQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASP 467 >gi|9945318 MAX binding protein [Homo sapiens] Length = 582 Score = 44.3 bits (103), Expect = 2e-04 Identities = 87/327 (26%), Positives = 115/327 (35%), Gaps = 79/327 (24%) Query: 32 LPMVTTAPPPLPRIPDPRALP-PTLFLPHFLGGDGP-CLTPQPRAPAALPNRSLAVAGGT 89 LP+ APPP P P P A P P +P + + P L P P PAA LA Sbjct: 65 LPLSPPAPPPAP--PPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAAQPLPLAPRQPA 122 Query: 90 PRAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRS---PATGPSGAQEVPGPAAA 146 AP K+ PA LPSR Q P L ++ P P Q +P P Sbjct: 123 LVGAPGLSIKE-----PA-PLPSR-PQVPTPAPLLPDSKATIPPNGSPKPLQPLPTPVLT 175 Query: 147 LAPSPAAAAGTEGASPDLAPLRPAAPGQTPLRKEVLKSKMGKSEKIALPHG---QLVHG- 202 +AP P G P LAP +P P L K ++ SE+ P G + VH Sbjct: 176 IAPHP-------GVQPQLAPQQPPPPTLGTL-KLAPAEEVKSSEQKKRPGGIGTREVHNK 227 Query: 203 ------IHLYE--------QPKINRQK----SKYNLPLTKITSAKRNENNF--------- 235 HL E P ++ +K S L I S KR E + Sbjct: 228 LEKNRRAHLKECFETLKRNIPNVDDKKTSNLSVLRTALRYIQSLKRKEKEYEHEMERLAR 287 Query: 236 ------------------WQDSVSSDRIQKQEKKPFKNTENIKNSHLKKSAFLTEVSQKE 277 W D + DR+ +Q +P + S + + +E Sbjct: 288 EKIATQQRLAELKHELSQWMDVLEIDRVLRQTGQP--EDDQASTSTASEGEDNIDEDMEE 345 Query: 278 NYAG---AKFSDPPSPSVLPK---PPS 298 + AG K S P P +L PPS Sbjct: 346 DRAGLGPPKLSHRPQPELLKSTLPPPS 372 Score = 31.6 bits (70), Expect = 1.0 Identities = 37/132 (28%), Positives = 45/132 (34%), Gaps = 28/132 (21%) Query: 32 LPMVTTAPPPLPRIPDPR----ALPPTLFLPHFLGGDGPCLTPQPRAPAALPNRSLAVAG 87 LP +T P PLP P P ALPP P QP+ LP A Sbjct: 368 LPPPSTTPAPLPPHPHPHPHSVALPPAHL---------PVQQQQPQQKTPLP------AP 412 Query: 88 GTPRAAPKKR---RKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATGPSG------AQ 138 P AAP + + A+ G H H ++ GP G A Sbjct: 413 PPPPAAPAQTLVPAPAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQGPGGKHIAHIAP 472 Query: 139 EVPGPAAALAPS 150 P PA LAP+ Sbjct: 473 SAPSPAVQLAPA 484 >gi|42475970 synapse defective 1, Rho GTPase, homolog 1 [Homo sapiens] Length = 735 Score = 44.3 bits (103), Expect = 2e-04 Identities = 44/150 (29%), Positives = 61/150 (40%), Gaps = 39/150 (26%) Query: 41 PLPRIPDPRALPPTLFLPHFLGGDGPCLTPQPRAPAALPNRSLAVAGGTP--------RA 92 P+P DPR P P + L PQ APA+ P ++ P + Sbjct: 114 PIPE-EDPRPPAPEPPGPQPGSAESEGLAPQGAAPASPPTKASRTKSPGPARRLSIKMKK 172 Query: 93 APKKRRK----------KKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATGPSGAQEVPG 142 P+ RR+ ++ RA+PAG + SR+H S GG PA GP G + Sbjct: 173 LPELRRRLSLRGPRAGRERERAAPAGSVISRYHL-----DSSVGGPGPAAGPGGTR---- 223 Query: 143 PAAALAPSPAAAAGTEGASPDLAPLRPAAP 172 SP A ++G SP+ RPA P Sbjct: 224 -------SPRAGYLSDGDSPE----RPAGP 242 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 43.9 bits (102), Expect = 2e-04 Identities = 45/158 (28%), Positives = 59/158 (37%), Gaps = 20/158 (12%) Query: 33 PMVTTAPPPLPRIPDPRALP----------PTLFLPH-FLGGD--GPCLTPQPRAPAALP 79 P +APP L +P P A P PTL H FL P TP P+AP AL Sbjct: 342 PPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALA 401 Query: 80 NRSLAVAGGTPRAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATGPSGAQE 139 L P + P A+P+ Q P+ + P P P Sbjct: 402 LPPLQAPPSPPASPP-----LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 456 Query: 140 VPGPAAALAPSPAAAAGTEGASP-DLAPLRPAAPGQTP 176 P P + A P+ A + A P + P PA+P +P Sbjct: 457 SP-PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP 493 Score = 40.8 bits (94), Expect = 0.002 Identities = 47/147 (31%), Positives = 57/147 (38%), Gaps = 21/147 (14%) Query: 38 APPPLPRIPDPRALPPTLFLPHFLGGD--------GPCLTPQPRAPAALPNRSLAVAGGT 89 +PP P P PP+L P P TP P+AP L L +A Sbjct: 457 SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPP 516 Query: 90 PRAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSP-ATGPSGAQEV-PGPAAAL 147 P+ AP ++A P+ P+ F PS SP AT P A V P + Sbjct: 517 PQ-APPALATPPLQALPSP--PASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQV 573 Query: 148 APSPAAAAGTEGASPDL-APLRPAAPG 173 PSP ASP L AP RP PG Sbjct: 574 PPSPP-------ASPTLQAPRRPPTPG 593 Score = 37.0 bits (84), Expect = 0.024 Identities = 45/149 (30%), Positives = 60/149 (40%), Gaps = 25/149 (16%) Query: 33 PMVTTAPPPLPRIPDPRALPPTLF------LPHFLGGDGPCLTPQPRAPAALPNRS---- 82 PM +A PP P+ P P A PP P L P L P PA+ P ++ Sbjct: 490 PMSPSATPP-PQAPPPLAAPPLQLAKPPPQAPPALA--TPPLQALPSPPASFPGQAPFSP 546 Query: 83 LAVAGGTPRAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATGPSGAQEVPG 142 A +P A P + V A+P Q+P P+L+ R P T P V G Sbjct: 547 SASLPMSPLATPPP-QAPPVLAAPLLQVPPS----PPASPTLQAPRRPPT-PGPDTSVSG 600 Query: 143 PAAALA------PSPAAAAGTEGASPDLA 165 P LA P P+ + + + PDLA Sbjct: 601 PRLTLALAPGPPPPPSRSPSSTLSGPDLA 629 Score = 34.7 bits (78), Expect = 0.12 Identities = 54/190 (28%), Positives = 64/190 (33%), Gaps = 46/190 (24%) Query: 34 MVTTAPPPLPRIPDPRALPPTLF------------LPHFLGGDGPCLTPQPRAPAALPNR 81 ++T PP PR P P P L L GG G P+ AP A P R Sbjct: 24 LLTPRPPGSPR-PPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPES-APRAGPTR 81 Query: 82 SLAVAGGTP-----------RAAPKK-----------RRKKKVRASPAGQLPSRFHQYQQ 119 S + P RA P K R R P GQ R + Sbjct: 82 SAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEET 141 Query: 120 --HRPSLEGGRSPATGPSGAQEVPGPAAALAPSPAAA-----AGTEGASPDLAP-LRPAA 171 + E + A ++ GP PSPA A AGTE P AP RP Sbjct: 142 VARGKATEAPKRSALSAGARRDTSGPTPG-TPSPAMARRSRAAGTEVGLPRPAPSARPRP 200 Query: 172 PGQTPLRKEV 181 P + P RK V Sbjct: 201 PTEGP-RKSV 209 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 43.9 bits (102), Expect = 2e-04 Identities = 45/158 (28%), Positives = 59/158 (37%), Gaps = 20/158 (12%) Query: 33 PMVTTAPPPLPRIPDPRALP----------PTLFLPH-FLGGD--GPCLTPQPRAPAALP 79 P +APP L +P P A P PTL H FL P TP P+AP AL Sbjct: 303 PPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALA 362 Query: 80 NRSLAVAGGTPRAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATGPSGAQE 139 L P + P A+P+ Q P+ + P P P Sbjct: 363 LPPLQAPPSPPASPP-----LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 417 Query: 140 VPGPAAALAPSPAAAAGTEGASP-DLAPLRPAAPGQTP 176 P P + A P+ A + A P + P PA+P +P Sbjct: 418 SP-PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP 454 Score = 40.8 bits (94), Expect = 0.002 Identities = 47/147 (31%), Positives = 57/147 (38%), Gaps = 21/147 (14%) Query: 38 APPPLPRIPDPRALPPTLFLPHFLGGD--------GPCLTPQPRAPAALPNRSLAVAGGT 89 +PP P P PP+L P P TP P+AP L L +A Sbjct: 418 SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPP 477 Query: 90 PRAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSP-ATGPSGAQEV-PGPAAAL 147 P+ AP ++A P+ P+ F PS SP AT P A V P + Sbjct: 478 PQ-APPALATPPLQALPSP--PASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQV 534 Query: 148 APSPAAAAGTEGASPDL-APLRPAAPG 173 PSP ASP L AP RP PG Sbjct: 535 PPSPP-------ASPTLQAPRRPPTPG 554 Score = 37.0 bits (84), Expect = 0.024 Identities = 45/149 (30%), Positives = 60/149 (40%), Gaps = 25/149 (16%) Query: 33 PMVTTAPPPLPRIPDPRALPPTLF------LPHFLGGDGPCLTPQPRAPAALPNRS---- 82 PM +A PP P+ P P A PP P L P L P PA+ P ++ Sbjct: 451 PMSPSATPP-PQAPPPLAAPPLQLAKPPPQAPPALA--TPPLQALPSPPASFPGQAPFSP 507 Query: 83 LAVAGGTPRAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATGPSGAQEVPG 142 A +P A P + V A+P Q+P P+L+ R P T P V G Sbjct: 508 SASLPMSPLATPPP-QAPPVLAAPLLQVPPS----PPASPTLQAPRRPPT-PGPDTSVSG 561 Query: 143 PAAALA------PSPAAAAGTEGASPDLA 165 P LA P P+ + + + PDLA Sbjct: 562 PRLTLALAPGPPPPPSRSPSSTLSGPDLA 590 Score = 34.7 bits (78), Expect = 0.12 Identities = 53/181 (29%), Positives = 64/181 (35%), Gaps = 37/181 (20%) Query: 34 MVTTAPPPLPRIPDPRALPPTLF------------LPHFLGGDGPCLTPQPRAPAALPNR 81 ++T PP PR P P P L L GG G P+ AP A P R Sbjct: 24 LLTPRPPGSPR-PPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPES-APRAGPTR 81 Query: 82 SLA--VAGGTPRAAPKK-----------RRKKKVRASPAGQLPSRFHQYQQ--HRPSLEG 126 + +G RA P K R R P GQ R + + E Sbjct: 82 TSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEA 141 Query: 127 GRSPATGPSGAQEVPGPAAALAPSPAAA-----AGTEGASPDLAP-LRPAAPGQTPLRKE 180 + A ++ GP PSPA A AGTE P AP RP P + P RK Sbjct: 142 PKRSALSAGARRDTSGPTPG-TPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGP-RKS 199 Query: 181 V 181 V Sbjct: 200 V 200 Score = 30.8 bits (68), Expect = 1.7 Identities = 30/98 (30%), Positives = 38/98 (38%), Gaps = 14/98 (14%) Query: 75 PAALPNRSLAVAGGTPRAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATGP 134 P + P RS A GTPRA + K P G R Q R +PA GP Sbjct: 239 PLSSPARSGPSARGTPRAPAHPSQPK-----PKGLQALRPPQVTPPRKDA----APALGP 289 Query: 135 SGAQEVPGPAAALAPSPAAAAGTEGASPDLAPLRPAAP 172 + + P+ + PSP+A S P PA P Sbjct: 290 LSSSPLATPSPSAPPSPSAP-----PSLQTLPSPPATP 322 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 43.1 bits (100), Expect = 3e-04 Identities = 48/168 (28%), Positives = 61/168 (36%), Gaps = 22/168 (13%) Query: 31 ALPMVTT--APPPLPRIPDPRALPPTLFLPHFLGGDGPC----LTPQPRAPAALPNRSLA 84 A P++ T +PPP DP +PP + P GP + P P + L SL Sbjct: 974 AAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLV 1033 Query: 85 VAGGTPRAAPKKRRKKKVRA--SPAGQLPSRFHQYQQHRPSLE---GGRSPATGPSGAQE 139 P V + SP G++ + + H E PA PS Sbjct: 1034 PQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSP 1093 Query: 140 VPGPAAAL---APSPAAAAGT-EGASPDLAPL-------RPAAPGQTP 176 +P P L APSPA A G D APL PGQTP Sbjct: 1094 LPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTP 1141 Score = 35.8 bits (81), Expect = 0.053 Identities = 40/169 (23%), Positives = 55/169 (32%), Gaps = 12/169 (7%) Query: 40 PPLPRIPDPRALPPTLFLPHFLG-GDGPCLTPQPRAPAALPNRSLAVAGGTPRAAPKKRR 98 P L P+ L P PH + PCL+PQP P P + Sbjct: 795 PHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPE 854 Query: 99 KKKVRASP--------AGQLPSRFHQYQQHRPSLEGGRSPATGPSGAQEVPGPAAALAPS 150 +K SP GQ P+ + P E SP G E P + P Sbjct: 855 LEKPPLSPRPEKPPEEPGQCPAP-EELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPE 913 Query: 151 --PAAAAGTEGASPDLAPLRPAAPGQTPLRKEVLKSKMGKSEKIALPHG 197 P + +G SP L P P P +P+ + ++ P G Sbjct: 914 ELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFG 962 Score = 30.0 bits (66), Expect = 2.9 Identities = 20/57 (35%), Positives = 24/57 (42%), Gaps = 3/57 (5%) Query: 121 RPSLEGGRSPATGPSGAQEV-PGPAAALAPSPAAAAGTEGASPDLAPLRPAAPGQTP 176 +P L G P TGP QE+ GP P A G P L P+ P P +P Sbjct: 4260 QPQLGGFPGPQTGP--LQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSP 4314 >gi|239743660 PREDICTED: hypothetical protein XP_002342926 [Homo sapiens] Length = 329 Score = 42.7 bits (99), Expect = 4e-04 Identities = 43/148 (29%), Positives = 58/148 (39%), Gaps = 43/148 (29%) Query: 48 PRALPPTLFLPHFLGGDGPCLTPQPRA---------------PAALPNRSLAVAGGTPRA 92 PRA PP GG G TP P+A P+ P R L + PR Sbjct: 207 PRAFPP--------GGPGDAGTPMPKAGGLRKRPGITRTEGNPSPRPPRRLTLPEDHPRL 258 Query: 93 APKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATGPSGAQEVPGPAAALAPSPA 152 A +RR+K+ A+ + RP+ + P GP G GPA ++ SPA Sbjct: 259 ANARRRRKRALAT-------------RVRPAPQTSGRP--GPLG-----GPAISVVLSPA 298 Query: 153 AAAGTEGASPDLAPLRPAAPGQTPLRKE 180 + A +G S R GQ P R + Sbjct: 299 SQAPEKGWSQSRGGARLGPEGQEPGRDQ 326 >gi|14602439 Williams Beuren syndrome chromosome region 14 isoform delta [Homo sapiens] Length = 831 Score = 42.4 bits (98), Expect = 6e-04 Identities = 45/156 (28%), Positives = 60/156 (38%), Gaps = 19/156 (12%) Query: 39 PPPLPRIPDPRAL--PPTLFLPHF---LGGDGPCLTPQPRAPAALPNRSLAVAGGTPRAA 93 PPP P + P AL LF P F P ++P P APAA P +V P Sbjct: 412 PPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLP-APAAFPPTPQSVPSPAPTPF 470 Query: 94 PKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATGPSGAQEVPGPAAALAPSPAA 153 P + P G F S+ G+ PA P G + P A SP Sbjct: 471 P-------IELLPLGYSEPAFGPCF----SMPRGKPPAPSPRGQKASPPTLAPATASPPT 519 Query: 154 AAGTEGASPDLAPLRPAAPGQTPLRKEVLKSKMGKS 189 AG+ +P L L AA + L ++ S + +S Sbjct: 520 TAGSN--NPCLTQLLTAAKPEQALEPPLVSSTLLRS 553 Score = 38.5 bits (88), Expect = 0.008 Identities = 45/173 (26%), Positives = 58/173 (33%), Gaps = 39/173 (22%) Query: 2 TVVSVPQREPLVLGGRLAPLGFSSRGYFGALPMVTTAPPPLPRIPDPRALPPTL-----F 56 T SVP P L PLG+S FG + PP P +A PPTL Sbjct: 458 TPQSVPSPAPTPFPIELLPLGYSEPA-FGPCFSMPRGKPPAPSPRGQKASPPTLAPATAS 516 Query: 57 LPHFLGGDGPCLT-------PQPRAPAALPNRSLAVAGGTPRAAPKKRRKKKVRASPAGQ 109 P G + PCLT P+ L + +L + G+P ++ V P Sbjct: 517 PPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSP--------QETVPEFPCTF 568 Query: 110 LPSRFHQYQQHRPSLEGGRSPATGPSGAQEVPGPAAALAPSPAAAAGTEGASP 162 LP P P+ + PGPA P E SP Sbjct: 569 LP------------------PTPAPTPPRPPPGPATLAPSRPLLVPKAERLSP 603 >gi|14602437 Williams Beuren syndrome chromosome region 14 isoform gamma [Homo sapiens] Length = 850 Score = 42.4 bits (98), Expect = 6e-04 Identities = 45/156 (28%), Positives = 60/156 (38%), Gaps = 19/156 (12%) Query: 39 PPPLPRIPDPRAL--PPTLFLPHF---LGGDGPCLTPQPRAPAALPNRSLAVAGGTPRAA 93 PPP P + P AL LF P F P ++P P APAA P +V P Sbjct: 412 PPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLP-APAAFPPTPQSVPSPAPTPF 470 Query: 94 PKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATGPSGAQEVPGPAAALAPSPAA 153 P + P G F S+ G+ PA P G + P A SP Sbjct: 471 P-------IELLPLGYSEPAFGPCF----SMPRGKPPAPSPRGQKASPPTLAPATASPPT 519 Query: 154 AAGTEGASPDLAPLRPAAPGQTPLRKEVLKSKMGKS 189 AG+ +P L L AA + L ++ S + +S Sbjct: 520 TAGSN--NPCLTQLLTAAKPEQALEPPLVSSTLLRS 553 Score = 38.5 bits (88), Expect = 0.008 Identities = 45/173 (26%), Positives = 58/173 (33%), Gaps = 39/173 (22%) Query: 2 TVVSVPQREPLVLGGRLAPLGFSSRGYFGALPMVTTAPPPLPRIPDPRALPPTL-----F 56 T SVP P L PLG+S FG + PP P +A PPTL Sbjct: 458 TPQSVPSPAPTPFPIELLPLGYSEPA-FGPCFSMPRGKPPAPSPRGQKASPPTLAPATAS 516 Query: 57 LPHFLGGDGPCLT-------PQPRAPAALPNRSLAVAGGTPRAAPKKRRKKKVRASPAGQ 109 P G + PCLT P+ L + +L + G+P ++ V P Sbjct: 517 PPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSP--------QETVPEFPCTF 568 Query: 110 LPSRFHQYQQHRPSLEGGRSPATGPSGAQEVPGPAAALAPSPAAAAGTEGASP 162 LP P P+ + PGPA P E SP Sbjct: 569 LP------------------PTPAPTPPRPPPGPATLAPSRPLLVPKAERLSP 603 >gi|14602435 Williams Beuren syndrome chromosome region 14 isoform beta [Homo sapiens] Length = 833 Score = 42.4 bits (98), Expect = 6e-04 Identities = 45/156 (28%), Positives = 60/156 (38%), Gaps = 19/156 (12%) Query: 39 PPPLPRIPDPRAL--PPTLFLPHF---LGGDGPCLTPQPRAPAALPNRSLAVAGGTPRAA 93 PPP P + P AL LF P F P ++P P APAA P +V P Sbjct: 412 PPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLP-APAAFPPTPQSVPSPAPTPF 470 Query: 94 PKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATGPSGAQEVPGPAAALAPSPAA 153 P + P G F S+ G+ PA P G + P A SP Sbjct: 471 P-------IELLPLGYSEPAFGPCF----SMPRGKPPAPSPRGQKASPPTLAPATASPPT 519 Query: 154 AAGTEGASPDLAPLRPAAPGQTPLRKEVLKSKMGKS 189 AG+ +P L L AA + L ++ S + +S Sbjct: 520 TAGSN--NPCLTQLLTAAKPEQALEPPLVSSTLLRS 553 Score = 38.5 bits (88), Expect = 0.008 Identities = 45/173 (26%), Positives = 58/173 (33%), Gaps = 39/173 (22%) Query: 2 TVVSVPQREPLVLGGRLAPLGFSSRGYFGALPMVTTAPPPLPRIPDPRALPPTL-----F 56 T SVP P L PLG+S FG + PP P +A PPTL Sbjct: 458 TPQSVPSPAPTPFPIELLPLGYSEPA-FGPCFSMPRGKPPAPSPRGQKASPPTLAPATAS 516 Query: 57 LPHFLGGDGPCLT-------PQPRAPAALPNRSLAVAGGTPRAAPKKRRKKKVRASPAGQ 109 P G + PCLT P+ L + +L + G+P ++ V P Sbjct: 517 PPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSP--------QETVPEFPCTF 568 Query: 110 LPSRFHQYQQHRPSLEGGRSPATGPSGAQEVPGPAAALAPSPAAAAGTEGASP 162 LP P P+ + PGPA P E SP Sbjct: 569 LP------------------PTPAPTPPRPPPGPATLAPSRPLLVPKAERLSP 603 >gi|14602433 Williams Beuren syndrome chromosome region 14 isoform alpha [Homo sapiens] Length = 852 Score = 42.4 bits (98), Expect = 6e-04 Identities = 45/156 (28%), Positives = 60/156 (38%), Gaps = 19/156 (12%) Query: 39 PPPLPRIPDPRAL--PPTLFLPHF---LGGDGPCLTPQPRAPAALPNRSLAVAGGTPRAA 93 PPP P + P AL LF P F P ++P P APAA P +V P Sbjct: 412 PPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLP-APAAFPPTPQSVPSPAPTPF 470 Query: 94 PKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATGPSGAQEVPGPAAALAPSPAA 153 P + P G F S+ G+ PA P G + P A SP Sbjct: 471 P-------IELLPLGYSEPAFGPCF----SMPRGKPPAPSPRGQKASPPTLAPATASPPT 519 Query: 154 AAGTEGASPDLAPLRPAAPGQTPLRKEVLKSKMGKS 189 AG+ +P L L AA + L ++ S + +S Sbjct: 520 TAGSN--NPCLTQLLTAAKPEQALEPPLVSSTLLRS 553 Score = 38.5 bits (88), Expect = 0.008 Identities = 45/173 (26%), Positives = 58/173 (33%), Gaps = 39/173 (22%) Query: 2 TVVSVPQREPLVLGGRLAPLGFSSRGYFGALPMVTTAPPPLPRIPDPRALPPTL-----F 56 T SVP P L PLG+S FG + PP P +A PPTL Sbjct: 458 TPQSVPSPAPTPFPIELLPLGYSEPA-FGPCFSMPRGKPPAPSPRGQKASPPTLAPATAS 516 Query: 57 LPHFLGGDGPCLT-------PQPRAPAALPNRSLAVAGGTPRAAPKKRRKKKVRASPAGQ 109 P G + PCLT P+ L + +L + G+P ++ V P Sbjct: 517 PPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSP--------QETVPEFPCTF 568 Query: 110 LPSRFHQYQQHRPSLEGGRSPATGPSGAQEVPGPAAALAPSPAAAAGTEGASP 162 LP P P+ + PGPA P E SP Sbjct: 569 LP------------------PTPAPTPPRPPPGPATLAPSRPLLVPKAERLSP 603 >gi|194733742 Wolf-Hirschhorn syndrome candidate 2 protein [Homo sapiens] Length = 539 Score = 42.4 bits (98), Expect = 6e-04 Identities = 32/118 (27%), Positives = 48/118 (40%), Gaps = 8/118 (6%) Query: 66 PCLTPQPRAPAALPNRSLAVAGGTPRAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLE 125 P + P P+ +P S + TP AP R + P+ P+ Q++Q P Sbjct: 331 PSTSYLPSTPSVVPASSYIPSSETP-PAPSSREASRPPEEPSAPSPTLPAQFKQRAPMYN 389 Query: 126 GGRSPATGPSGAQEVPGPAAALAPSPAAAAGTEGASPDLAPLRP--AAPGQTPLRKEV 181 G SPAT A P + L P+ A +P +A + P AP Q +K + Sbjct: 390 SGLSPATPTPAA-----PTSPLTPTTPPAVAPTTQTPPVAMVAPQTQAPAQQQPKKNL 442 >gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens] Length = 987 Score = 42.4 bits (98), Expect = 6e-04 Identities = 49/179 (27%), Positives = 68/179 (37%), Gaps = 34/179 (18%) Query: 32 LPMVTTAPPP--------------LPRIPDPRALPPTLFLPHFLGGDGPCLTPQPRAPAA 77 LP TA PP L ++ P +LPP P G P+ P+ Sbjct: 312 LPAAATASPPTSLLAPSTNPLLESLKKMQTPPSLPPC---PESAGAATTEALSPPKTPSL 368 Query: 78 LPNRSLAVAGGTPRAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATGPS-G 136 LP L+ +G P P K + G +P+ PS+ P+ Sbjct: 369 LPPLGLSQSG-PPGLLPSPSFDSKPPTTLLGLIPA---------PSMVPATDTKAPPTLQ 418 Query: 137 AQEVPGPAAALAPSPAAAA----GTEGASPDLAPLRPAAPGQTPLRKEVLKSKMGKSEK 191 A+ P A APSPA GT+ SP +P PAA +P+ K + + KSEK Sbjct: 419 AETATKPQATSAPSPAPKQSFLFGTQNTSPS-SPAAPAASSASPMFKPIFTAP-PKSEK 475 >gi|116284398 WAS/WASL interacting protein family, member 1 [Homo sapiens] Length = 503 Score = 42.0 bits (97), Expect = 7e-04 Identities = 44/162 (27%), Positives = 57/162 (35%), Gaps = 7/162 (4%) Query: 39 PPPLPRIPDP-RALPPTLFLPHFLGGDGPCLTPQPRAPAALPNRSLAVAGGTPRAAPKKR 97 PPP+P P P ++ P P GG +P P P NR A+ GG+ R +P Sbjct: 184 PPPVPSTPRPIQSSPHNRGSPPVPGGPRQP-SPGPTPPPFPGNRGTALGGGSIRQSPLSS 242 Query: 98 RKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATGPSGAQEVPGPAAALAPSPAAAAGT 157 P PSR + P G P+ A P P P P+ + Sbjct: 243 SSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHRE-AVPPPPPQNNKPPVPSTPRPS 301 Query: 158 EGASPDLAPLRPAAPGQTPLRKEVLKSKMGKSEKIALPHGQL 199 + P P+ PG PL S G E LP L Sbjct: 302 ASSQAPPPPPPPSRPGPPPLP----PSSSGNDETPRLPQRNL 339 Score = 35.8 bits (81), Expect = 0.053 Identities = 40/149 (26%), Positives = 51/149 (34%), Gaps = 38/149 (25%) Query: 39 PPPLPRIPDPRALPPTLFLPHFLGGDGPCLTPQPRAPAALPNRSLAVAGGTPRAA----- 93 PPP P P P LPP+ G TP+ LP R+L+++ TP Sbjct: 309 PPPPPSRPGPPPLPPS--------SSGNDETPR------LPQRNLSLSSSTPPLPSPGRS 354 Query: 94 ------PKKRRKKKVRASP--AGQLP-----------SRFHQYQQHRPSLEGGRSPATGP 134 P +R VR P +G LP SR PS G SP +GP Sbjct: 355 GPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGP 414 Query: 135 SGAQEVPGPAAALAPSPAAAAGTEGASPD 163 P+A P P + D Sbjct: 415 RPPLPPDRPSAGAPPPPPPSTSIRNGFQD 443 Score = 33.1 bits (74), Expect = 0.35 Identities = 31/91 (34%), Positives = 38/91 (41%), Gaps = 11/91 (12%) Query: 27 GYFGALPMVTTAPPPLPRIPDP-RALPPTLFLPHFLGGDGPCLTPQPRAPAALPNRSLAV 85 G G LP PPP+ R RALP T LP G D P P+P P P+ Sbjct: 374 GRSGPLP----PPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPS----- 424 Query: 86 AGGTPRAAPKKRRKKKVRASPA-GQLPSRFH 115 AG P P + + SP + SRF+ Sbjct: 425 AGAPPPPPPSTSIRNGFQDSPCEDEWESRFY 455 >gi|38373695 WAS/WASL interacting protein family, member 1 [Homo sapiens] Length = 503 Score = 42.0 bits (97), Expect = 7e-04 Identities = 44/162 (27%), Positives = 57/162 (35%), Gaps = 7/162 (4%) Query: 39 PPPLPRIPDP-RALPPTLFLPHFLGGDGPCLTPQPRAPAALPNRSLAVAGGTPRAAPKKR 97 PPP+P P P ++ P P GG +P P P NR A+ GG+ R +P Sbjct: 184 PPPVPSTPRPIQSSPHNRGSPPVPGGPRQP-SPGPTPPPFPGNRGTALGGGSIRQSPLSS 242 Query: 98 RKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATGPSGAQEVPGPAAALAPSPAAAAGT 157 P PSR + P G P+ A P P P P+ + Sbjct: 243 SSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHRE-AVPPPPPQNNKPPVPSTPRPS 301 Query: 158 EGASPDLAPLRPAAPGQTPLRKEVLKSKMGKSEKIALPHGQL 199 + P P+ PG PL S G E LP L Sbjct: 302 ASSQAPPPPPPPSRPGPPPLP----PSSSGNDETPRLPQRNL 339 Score = 35.8 bits (81), Expect = 0.053 Identities = 40/149 (26%), Positives = 51/149 (34%), Gaps = 38/149 (25%) Query: 39 PPPLPRIPDPRALPPTLFLPHFLGGDGPCLTPQPRAPAALPNRSLAVAGGTPRAA----- 93 PPP P P P LPP+ G TP+ LP R+L+++ TP Sbjct: 309 PPPPPSRPGPPPLPPS--------SSGNDETPR------LPQRNLSLSSSTPPLPSPGRS 354 Query: 94 ------PKKRRKKKVRASP--AGQLP-----------SRFHQYQQHRPSLEGGRSPATGP 134 P +R VR P +G LP SR PS G SP +GP Sbjct: 355 GPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGP 414 Query: 135 SGAQEVPGPAAALAPSPAAAAGTEGASPD 163 P+A P P + D Sbjct: 415 RPPLPPDRPSAGAPPPPPPSTSIRNGFQD 443 Score = 33.1 bits (74), Expect = 0.35 Identities = 31/91 (34%), Positives = 38/91 (41%), Gaps = 11/91 (12%) Query: 27 GYFGALPMVTTAPPPLPRIPDP-RALPPTLFLPHFLGGDGPCLTPQPRAPAALPNRSLAV 85 G G LP PPP+ R RALP T LP G D P P+P P P+ Sbjct: 374 GRSGPLP----PPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPS----- 424 Query: 86 AGGTPRAAPKKRRKKKVRASPA-GQLPSRFH 115 AG P P + + SP + SRF+ Sbjct: 425 AGAPPPPPPSTSIRNGFQDSPCEDEWESRFY 455 >gi|116256363 transmembrane protease, serine 13 [Homo sapiens] Length = 567 Score = 42.0 bits (97), Expect = 7e-04 Identities = 31/112 (27%), Positives = 48/112 (42%) Query: 73 RAPAALPNRSLAVAGGTPRAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPAT 132 R P+A + + A GTP + +ASPAG P R Q GR+ Sbjct: 13 RTPSAGASPAQASPAGTPPGRASPAQASPAQASPAGTPPGRASPAQASPAGTPPGRASPG 72 Query: 133 GPSGAQEVPGPAAALAPSPAAAAGTEGASPDLAPLRPAAPGQTPLRKEVLKS 184 S AQ P A+ SPA A+ + +S + R A+ +P R ++++ Sbjct: 73 RASPAQASPAQASPARASPALASLSRSSSGRSSSARSASVTTSPTRVYLVRA 124 >gi|145309322 insulinoma-associated protein IA-6 [Homo sapiens] Length = 566 Score = 41.6 bits (96), Expect = 0.001 Identities = 34/100 (34%), Positives = 42/100 (42%), Gaps = 14/100 (14%) Query: 66 PCLTPQPRAPAALPNRSLAVAGGTPRAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLE 125 P L PQ AP L A G RA P R + P L + + Q P Sbjct: 27 PLLGPQG-APPFLEEAPSASLPGAERATPPTREE------PGKGLTAEAAREQSGSPCRA 79 Query: 126 GGRSPATGP-------SGAQEVPGPAAALAPSPAAAAGTE 158 G SP TG +G +E PGP+ + +PSPA AG E Sbjct: 80 AGVSPGTGGREGAEWRAGGREGPGPSPSPSPSPAKPAGAE 119 Score = 30.0 bits (66), Expect = 2.9 Identities = 53/168 (31%), Positives = 66/168 (39%), Gaps = 26/168 (15%) Query: 17 RLAPLGFSSRGYFGALPMVTTAPPP-LPRIPDPRALPPTLFLPHFLGGDGPCLTPQP-RA 74 RLA F G GA P + AP LP RA PPT P G LT + R Sbjct: 20 RLAERVFPLLGPQGAPPFLEEAPSASLPGAE--RATPPTREEP------GKGLTAEAARE 71 Query: 75 PAALPNRSLAVAGGTP-------RAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGG 127 + P R+ V+ GT RA ++ SP+ P++ + R LE Sbjct: 72 QSGSPCRAAGVSPGTGGREGAEWRAGGREGPGPSPSPSPS---PAKPAGAELRRAFLERC 128 Query: 128 RSPATGPSGAQEVPGPAAALAP---SPAAAAGTEGASPDLAPLRPAAP 172 S P A+ PG AAA+A S A AA L PLR P Sbjct: 129 LS---SPVSAESFPGGAAAVAAFSCSVAPAAAPTPGEQFLLPLRAPFP 173 >gi|148237270 hypermethylated in cancer 1 isoform 2 [Homo sapiens] Length = 733 Score = 41.6 bits (96), Expect = 0.001 Identities = 43/165 (26%), Positives = 63/165 (38%), Gaps = 14/165 (8%) Query: 15 GGRLAPLGFSSRGYFGALPMVTTA-PPPLPRIPDPRALPPTLFLPHFLGGDGPCLTPQPR 73 GG AP G RG A P++ P P+ P P A PP+ G + T Sbjct: 165 GGGYAPYGRPGRGLRAATPVIQACYPSPVGPPPPPAAEPPS-------GPEAAVNTHCAE 217 Query: 74 APAALPNRSLAVAGGTPRAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATG 133 A+ P + A+ R +P ++ P P R ++ P + P+ G Sbjct: 218 LYASGPGPAAALCASERRCSPLCGLDLSKKSPPGSAAPERPLAERELPPRPDS--PPSAG 275 Query: 134 PSGAQEVPGPAAALAPSPAAAAGTEGASPDLAPLR--PAAPGQTP 176 P+ +E P +L P P E A+P P R +PG P Sbjct: 276 PAAYKEPPLALPSLPPLPFQK--LEEAAPPSDPFRGGSGSPGPEP 318 >gi|61676186 hypermethylated in cancer 1 isoform 1 [Homo sapiens] Length = 714 Score = 41.6 bits (96), Expect = 0.001 Identities = 43/165 (26%), Positives = 63/165 (38%), Gaps = 14/165 (8%) Query: 15 GGRLAPLGFSSRGYFGALPMVTTA-PPPLPRIPDPRALPPTLFLPHFLGGDGPCLTPQPR 73 GG AP G RG A P++ P P+ P P A PP+ G + T Sbjct: 146 GGGYAPYGRPGRGLRAATPVIQACYPSPVGPPPPPAAEPPS-------GPEAAVNTHCAE 198 Query: 74 APAALPNRSLAVAGGTPRAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGRSPATG 133 A+ P + A+ R +P ++ P P R ++ P + P+ G Sbjct: 199 LYASGPGPAAALCASERRCSPLCGLDLSKKSPPGSAAPERPLAERELPPRPDS--PPSAG 256 Query: 134 PSGAQEVPGPAAALAPSPAAAAGTEGASPDLAPLR--PAAPGQTP 176 P+ +E P +L P P E A+P P R +PG P Sbjct: 257 PAAYKEPPLALPSLPPLPFQK--LEEAAPPSDPFRGGSGSPGPEP 299 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.312 0.130 0.388 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,427,244 Number of Sequences: 37866 Number of extensions: 1068989 Number of successful extensions: 9751 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 111 Number of HSP's successfully gapped in prelim test: 898 Number of HSP's that attempted gapping in prelim test: 7294 Number of HSP's gapped (non-prelim): 2902 length of query: 327 length of database: 18,247,518 effective HSP length: 103 effective length of query: 224 effective length of database: 14,347,320 effective search space: 3213799680 effective search space used: 3213799680 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.