Search of human proteins with 5730073

Search of human proteins with 5730073

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5730073 KH domain containing, RNA binding, signal
transduction associated 3 [Homo sapiens]
         (346 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5730073 KH domain containing, RNA binding, signal transductio...   711   0.0  
gi|189217895 KH domain-containing, RNA-binding, signal transduct...   446   e-125
gi|5730027 KH domain containing, RNA binding, signal transductio...   375   e-104
gi|45827712 quaking homolog, KH domain RNA binding isoform HQK-7...   137   1e-32
gi|45827710 quaking homolog, KH domain RNA binding isoform HQK-7...   137   1e-32
gi|45827708 quaking homolog, KH domain RNA binding isoform HQK-6...   137   1e-32
gi|45827706 quaking homolog, KH domain RNA binding isoform HQK-5...   137   1e-32
gi|42544123 splicing factor 1 isoform 3 [Homo sapiens]                 82   9e-16
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]                 82   9e-16
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]                 82   9e-16
gi|56699409 RNA binding motif protein, X-linked [Homo sapiens]         48   1e-05
gi|242117971 RNA binding motif protein, X-linked-like 1 [Homo sa...    47   3e-05
gi|21361809 RNA binding motif protein, X-linked-like 1 [Homo sap...    47   3e-05
gi|128485756 hexaribonucleotide binding protein 3 [Homo sapiens]       43   5e-04
gi|238624257 insulin-like growth factor 2 mRNA binding protein 1...    41   0.001
gi|30795212 insulin-like growth factor 2 mRNA binding protein 3 ...    39   0.007
gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a ...    38   0.012
gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b ...    38   0.012
gi|14165437 heterogeneous nuclear ribonucleoprotein K isoform a ...    38   0.012
gi|215272410 ataxin 2-binding protein 1 isoform 5 [Homo sapiens]       38   0.015
gi|56237027 insulin-like growth factor 2 mRNA binding protein 1 ...    38   0.015
gi|38150007 small nuclear ribonucleoprotein polypeptide B/B' iso...    38   0.015
gi|4507125 small nuclear ribonucleoprotein polypeptide B/B' isof...    38   0.015
gi|156151396 heterogeneous nuclear ribonucleoprotein R isoform 3...    38   0.015
gi|156151394 heterogeneous nuclear ribonucleoprotein R isoform 1...    38   0.015
gi|156151392 heterogeneous nuclear ribonucleoprotein R isoform 4...    38   0.015
gi|5031755 heterogeneous nuclear ribonucleoprotein R isoform 2 [...    38   0.015
gi|4826974 RNA binding motif protein, Y-linked, family 1, member...    37   0.020
gi|54873602 hypothetical protein LOC220382 [Homo sapiens]              37   0.020
gi|56090527 RNA binding motif protein, Y-linked, family 1, membe...    37   0.020

>gi|5730073 KH domain containing, RNA binding, signal transduction
           associated 3 [Homo sapiens]
          Length = 346

 Score =  711 bits (1834), Expect = 0.0
 Identities = 346/346 (100%), Positives = 346/346 (100%)

Query: 1   MEEKYLPELMAEKDSLDPSFTHALRLVNQEIEKFQKGEGKDEEKYIDVVINKNMKLGQKV 60
           MEEKYLPELMAEKDSLDPSFTHALRLVNQEIEKFQKGEGKDEEKYIDVVINKNMKLGQKV
Sbjct: 1   MEEKYLPELMAEKDSLDPSFTHALRLVNQEIEKFQKGEGKDEEKYIDVVINKNMKLGQKV 60

Query: 61  LIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKY 120
           LIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKY
Sbjct: 61  LIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKY 120

Query: 121 FHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDEIRQAQLQELTYLNGGSEN 180
           FHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDEIRQAQLQELTYLNGGSEN
Sbjct: 121 FHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDEIRQAQLQELTYLNGGSEN 180

Query: 181 ADVPVVRGKPTLRTRGVPAPAITRGRGGVTARPVGVVVPRGTPTPRGVLSTRGPVSRGRG 240
           ADVPVVRGKPTLRTRGVPAPAITRGRGGVTARPVGVVVPRGTPTPRGVLSTRGPVSRGRG
Sbjct: 181 ADVPVVRGKPTLRTRGVPAPAITRGRGGVTARPVGVVVPRGTPTPRGVLSTRGPVSRGRG 240

Query: 241 LLTPRARGVPPTGYRPPPPPPTQETYGEYDYDDGYGTAYDEQSYDSYDNSYSTPAQSGAD 300
           LLTPRARGVPPTGYRPPPPPPTQETYGEYDYDDGYGTAYDEQSYDSYDNSYSTPAQSGAD
Sbjct: 241 LLTPRARGVPPTGYRPPPPPPTQETYGEYDYDDGYGTAYDEQSYDSYDNSYSTPAQSGAD 300

Query: 301 YYDYGHGLSEETYDSYGQEEWTNSRHKAPSARTAKGVYRDQPYGRY 346
           YYDYGHGLSEETYDSYGQEEWTNSRHKAPSARTAKGVYRDQPYGRY
Sbjct: 301 YYDYGHGLSEETYDSYGQEEWTNSRHKAPSARTAKGVYRDQPYGRY 346


>gi|189217895 KH domain-containing, RNA-binding, signal
           transduction-associated protein 2 [Homo sapiens]
          Length = 349

 Score =  446 bits (1148), Expect = e-125
 Identities = 234/355 (65%), Positives = 271/355 (76%), Gaps = 18/355 (5%)

Query: 2   EEKYLPELMAEKDSLDPSFTHALRLVNQEIEKFQKGEGK---DEEKYIDVVINKNMKLGQ 58
           EEKYLPELMAEKDSLDPSF HA RL+ +EIEKFQ  +GK   +E+KY+DV+ NKN+KL +
Sbjct: 3   EEKYLPELMAEKDSLDPSFVHASRLLAEEIEKFQGSDGKKEDEEKKYLDVISNKNIKLSE 62

Query: 59  KVLIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEA 118
           +VLIPVKQ+PKFNFVGKLLGPRGNSLKRLQEET  KMSILGKGSMRDKAKEEELRKSGEA
Sbjct: 63  RVLIPVKQYPKFNFVGKLLGPRGNSLKRLQEETGAKMSILGKGSMRDKAKEEELRKSGEA 122

Query: 119 KYFHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDEIRQAQLQELTYLNGGS 178
           KY HL+D+LHVLIEVFAPP EAY+RM HALEEIKKFL+PDYNDEIRQ QL+EL+YLNG  
Sbjct: 123 KYAHLSDELHVLIEVFAPPGEAYSRMSHALEEIKKFLVPDYNDEIRQEQLRELSYLNGSE 182

Query: 179 ENADVPVVRGKPTLRTRGVPAPAITRGRGGVTARPV----GVVVPRGTPTPRGVLSTRGP 234
           ++     +RG    R   +   A +RGRGG    P     GV+ PRG+   RG L    P
Sbjct: 183 DSGRGRGIRG----RGIRIAPTAPSRGRGGAIPPPPPPGRGVLTPRGSTVTRGALPV-PP 237

Query: 235 VSRGRGLLTPRARGVPPT-GYRPPPPPPTQETYGEYDYDDGYGTAYDEQSYDSYDNSYST 293
           V+  RG+ TPRARG P   GYR  PPPP  E Y EY YDDGYG  YD+Q+Y++YDNSY+T
Sbjct: 238 VA--RGVPTPRARGAPTVPGYR-APPPPAHEAYEEYGYDDGYGGEYDDQTYETYDNSYAT 294

Query: 294 PAQSGADYYDYGHGLSEETYDSYGQEEW--TNSRHKAPSARTAKGVYRDQPYGRY 346
             QS  +YYDYGHG+SE+ YDSY  EEW  T S  KAP  R+A+G YR+ PYGRY
Sbjct: 295 QTQSVPEYYDYGHGVSEDAYDSYAPEEWATTRSSLKAPPQRSARGGYREHPYGRY 349


>gi|5730027 KH domain containing, RNA binding, signal transduction
           associated 1 [Homo sapiens]
          Length = 443

 Score =  375 bits (964), Expect = e-104
 Identities = 208/360 (57%), Positives = 252/360 (70%), Gaps = 31/360 (8%)

Query: 2   EEKYLPELMAEKDSLDPSFTHALRLVNQEIEKFQKGEGK--DEEKYIDVVINKNMKLGQK 59
           E KYLPELMAEKDSLDPSFTHA++L+  EIEK QKG+ K  DEE Y+D+  +KNMKL ++
Sbjct: 100 ENKYLPELMAEKDSLDPSFTHAMQLLTAEIEKIQKGDSKKDDEENYLDLFSHKNMKLKER 159

Query: 60  VLIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAK 119
           VLIPVKQ+PKFNFVGK+LGP+GN++KRLQEET  K+S+LGKGSMRDKAKEEELRK G+ K
Sbjct: 160 VLIPVKQYPKFNFVGKILGPQGNTIKRLQEETGAKISVLGKGSMRDKAKEEELRKGGDPK 219

Query: 120 YFHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDEIRQAQLQELTYLNGGSE 179
           Y HLN DLHV IEVF PP EAYA M HA+EE+KKFL+PD  D+I Q Q  EL+YLNG  E
Sbjct: 220 YAHLNMDLHVFIEVFGPPCEAYALMAHAMEEVKKFLVPDMMDDICQEQFLELSYLNGVPE 279

Query: 180 NADVPVVRGKPTLRTRGV--PAPAITRGRGGVTARPVGVVVPRGTPTPRGVLSTRGPVSR 237
            +     RG P +R RG   P P + RGRG     P G +V RGTP  RG ++    V+R
Sbjct: 280 PSR---GRGVP-VRGRGAAPPPPPVPRGRG--VGPPRGALV-RGTPV-RGAITRGATVTR 331

Query: 238 G-------RGLLTPRAR--GVPPTGYRPPPPPPTQETYGEYDYDDGYGTAYDEQSYDSYD 288
           G       RG   PRAR  G+      P PPPP  ETY EY YDD     Y EQSY+ Y+
Sbjct: 332 GVPPPPTVRGAPAPRARTAGIQRI---PLPPPPAPETYEEYGYDD----TYAEQSYEGYE 384

Query: 289 NSYSTPAQSGADYYDYGHGLSEETYDSYGQEEWTNSRH--KAPSARTAKGVYRDQPYGRY 346
             YS  +Q  ++YYDYGHG  +++Y++YGQ++W  +R   KAP AR  KG YR+ PYGRY
Sbjct: 385 GYYS-QSQGDSEYYDYGHGEVQDSYEAYGQDDWNGTRPSLKAPPARPVKGAYREHPYGRY 443


>gi|45827712 quaking homolog, KH domain RNA binding isoform HQK-7B
           [Homo sapiens]
          Length = 319

 Score =  137 bits (346), Expect = 1e-32
 Identities = 101/286 (35%), Positives = 149/286 (52%), Gaps = 31/286 (10%)

Query: 5   YLPELMAEKDSLDPS------FTHALRLVNQEIEKFQKG------EGKDEEKYIDV--VI 50
           YL +LM +K  +         F H  RL+++EI + +K        G  E++  ++   +
Sbjct: 17  YLMQLMNDKKLMSSLPNFCGIFNHLERLLDEEISRVRKDMYNDTLNGSTEKRSAELPDAV 76

Query: 51  NKNMKLGQKVLIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEE 110
              ++L +K+ +PVK++P FNFVG++LGPRG + K+L+ ET  K+ + GKGSMRDK KEE
Sbjct: 77  GPIVQLQEKLYVPVKEYPDFNFVGRILGPRGLTAKQLEAETGCKIMVRGKGSMRDKKKEE 136

Query: 111 ELRKSGEAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIP--DYNDEIRQAQL 168
           + R  G+  + HLN+DLHVLI V      A  ++  A+EE+KK L+P  +  D +++ QL
Sbjct: 137 QNR--GKPNWEHLNEDLHVLITVEDAQNRAEIKLKRAVEEVKKLLVPAAEGEDSLKKMQL 194

Query: 169 QELTYLNGGSENADVPVVRGKPTLRTRGVPAPAITRGRGGVTARPVGVVVPRG--TPTPR 226
            EL  LNG   +A++       +L      AP I  G       P  V+ P    TPTP 
Sbjct: 195 MELAILNGTYRDANIKSPALAFSLAATAQAAPRIITG-------PAPVLPPAALRTPTPA 247

Query: 227 GVLSTRGPVSRGRGLLTPRARGVP-PTGYRPPPPPPTQETYGEYDY 271
           G   T  P+ R +        G P PT    PP P     Y  Y+Y
Sbjct: 248 G--PTIMPLIR-QIQTAVMPNGTPHPTAAIVPPGPEAGLIYTPYEY 290


>gi|45827710 quaking homolog, KH domain RNA binding isoform HQK-7
           [Homo sapiens]
          Length = 325

 Score =  137 bits (346), Expect = 1e-32
 Identities = 101/286 (35%), Positives = 149/286 (52%), Gaps = 31/286 (10%)

Query: 5   YLPELMAEKDSLDPS------FTHALRLVNQEIEKFQKG------EGKDEEKYIDV--VI 50
           YL +LM +K  +         F H  RL+++EI + +K        G  E++  ++   +
Sbjct: 17  YLMQLMNDKKLMSSLPNFCGIFNHLERLLDEEISRVRKDMYNDTLNGSTEKRSAELPDAV 76

Query: 51  NKNMKLGQKVLIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEE 110
              ++L +K+ +PVK++P FNFVG++LGPRG + K+L+ ET  K+ + GKGSMRDK KEE
Sbjct: 77  GPIVQLQEKLYVPVKEYPDFNFVGRILGPRGLTAKQLEAETGCKIMVRGKGSMRDKKKEE 136

Query: 111 ELRKSGEAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIP--DYNDEIRQAQL 168
           + R  G+  + HLN+DLHVLI V      A  ++  A+EE+KK L+P  +  D +++ QL
Sbjct: 137 QNR--GKPNWEHLNEDLHVLITVEDAQNRAEIKLKRAVEEVKKLLVPAAEGEDSLKKMQL 194

Query: 169 QELTYLNGGSENADVPVVRGKPTLRTRGVPAPAITRGRGGVTARPVGVVVPRG--TPTPR 226
            EL  LNG   +A++       +L      AP I  G       P  V+ P    TPTP 
Sbjct: 195 MELAILNGTYRDANIKSPALAFSLAATAQAAPRIITG-------PAPVLPPAALRTPTPA 247

Query: 227 GVLSTRGPVSRGRGLLTPRARGVP-PTGYRPPPPPPTQETYGEYDY 271
           G   T  P+ R +        G P PT    PP P     Y  Y+Y
Sbjct: 248 G--PTIMPLIR-QIQTAVMPNGTPHPTAAIVPPGPEAGLIYTPYEY 290


>gi|45827708 quaking homolog, KH domain RNA binding isoform HQK-6
           [Homo sapiens]
          Length = 319

 Score =  137 bits (346), Expect = 1e-32
 Identities = 101/286 (35%), Positives = 149/286 (52%), Gaps = 31/286 (10%)

Query: 5   YLPELMAEKDSLDPS------FTHALRLVNQEIEKFQKG------EGKDEEKYIDV--VI 50
           YL +LM +K  +         F H  RL+++EI + +K        G  E++  ++   +
Sbjct: 17  YLMQLMNDKKLMSSLPNFCGIFNHLERLLDEEISRVRKDMYNDTLNGSTEKRSAELPDAV 76

Query: 51  NKNMKLGQKVLIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEE 110
              ++L +K+ +PVK++P FNFVG++LGPRG + K+L+ ET  K+ + GKGSMRDK KEE
Sbjct: 77  GPIVQLQEKLYVPVKEYPDFNFVGRILGPRGLTAKQLEAETGCKIMVRGKGSMRDKKKEE 136

Query: 111 ELRKSGEAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIP--DYNDEIRQAQL 168
           + R  G+  + HLN+DLHVLI V      A  ++  A+EE+KK L+P  +  D +++ QL
Sbjct: 137 QNR--GKPNWEHLNEDLHVLITVEDAQNRAEIKLKRAVEEVKKLLVPAAEGEDSLKKMQL 194

Query: 169 QELTYLNGGSENADVPVVRGKPTLRTRGVPAPAITRGRGGVTARPVGVVVPRG--TPTPR 226
            EL  LNG   +A++       +L      AP I  G       P  V+ P    TPTP 
Sbjct: 195 MELAILNGTYRDANIKSPALAFSLAATAQAAPRIITG-------PAPVLPPAALRTPTPA 247

Query: 227 GVLSTRGPVSRGRGLLTPRARGVP-PTGYRPPPPPPTQETYGEYDY 271
           G   T  P+ R +        G P PT    PP P     Y  Y+Y
Sbjct: 248 G--PTIMPLIR-QIQTAVMPNGTPHPTAAIVPPGPEAGLIYTPYEY 290


>gi|45827706 quaking homolog, KH domain RNA binding isoform HQK-5
           [Homo sapiens]
          Length = 341

 Score =  137 bits (346), Expect = 1e-32
 Identities = 101/286 (35%), Positives = 149/286 (52%), Gaps = 31/286 (10%)

Query: 5   YLPELMAEKDSLDPS------FTHALRLVNQEIEKFQKG------EGKDEEKYIDV--VI 50
           YL +LM +K  +         F H  RL+++EI + +K        G  E++  ++   +
Sbjct: 17  YLMQLMNDKKLMSSLPNFCGIFNHLERLLDEEISRVRKDMYNDTLNGSTEKRSAELPDAV 76

Query: 51  NKNMKLGQKVLIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEE 110
              ++L +K+ +PVK++P FNFVG++LGPRG + K+L+ ET  K+ + GKGSMRDK KEE
Sbjct: 77  GPIVQLQEKLYVPVKEYPDFNFVGRILGPRGLTAKQLEAETGCKIMVRGKGSMRDKKKEE 136

Query: 111 ELRKSGEAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIP--DYNDEIRQAQL 168
           + R  G+  + HLN+DLHVLI V      A  ++  A+EE+KK L+P  +  D +++ QL
Sbjct: 137 QNR--GKPNWEHLNEDLHVLITVEDAQNRAEIKLKRAVEEVKKLLVPAAEGEDSLKKMQL 194

Query: 169 QELTYLNGGSENADVPVVRGKPTLRTRGVPAPAITRGRGGVTARPVGVVVPRG--TPTPR 226
            EL  LNG   +A++       +L      AP I  G       P  V+ P    TPTP 
Sbjct: 195 MELAILNGTYRDANIKSPALAFSLAATAQAAPRIITG-------PAPVLPPAALRTPTPA 247

Query: 227 GVLSTRGPVSRGRGLLTPRARGVP-PTGYRPPPPPPTQETYGEYDY 271
           G   T  P+ R +        G P PT    PP P     Y  Y+Y
Sbjct: 248 G--PTIMPLIR-QIQTAVMPNGTPHPTAAIVPPGPEAGLIYTPYEY 290


>gi|42544123 splicing factor 1 isoform 3 [Homo sapiens]
          Length = 548

 Score = 81.6 bits (200), Expect = 9e-16
 Identities = 67/238 (28%), Positives = 106/238 (44%), Gaps = 45/238 (18%)

Query: 55  KLGQKVLIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRK 114
           ++  KV+IP  ++P+ NFVG L+GPRGN+LK +++E   K+ I GKGS+    KE ++ +
Sbjct: 135 RVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGKGSV----KEGKVGR 190

Query: 115 SGEAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFL-----IPDYNDEIRQAQLQ 169
                    ++ LH L+      A     +  A+E+I+  L      P+  +++R+ QL+
Sbjct: 191 KDGQMLPGEDEPLHALV-----TANTMENVKKAVEQIRNILKQGIETPEDQNDLRKMQLR 245

Query: 170 ELTYLNGGSENADVPVVRGKPTLRTRGVPAPAITRGRGGV--------TARP-------- 213
           EL  LNG     D  ++R   +  TR +    +    GG           RP        
Sbjct: 246 ELARLNGTLREDDNRILRPWQSSETRSITNTTVCTKCGGAGHIASDCKFQRPGDPQSAQD 305

Query: 214 --------VGVVVPRG-TPTPRGVLSTRGPVSRGRGLLTPRARGVPPTGYRPPPPPPT 262
                   + ++   G  P P  V ST GP +      TP A    P      PPPP+
Sbjct: 306 KARMDKEYLSLMAELGEAPVPASVGSTSGPAT------TPLASAPRPAAPANNPPPPS 357



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 16/40 (40%), Positives = 21/40 (52%), Gaps = 9/40 (22%)

Query: 222 TPTPRGVLSTRGPVSRGRGLLTPRARGVPPTGYRPPPPPP 261
           TP   GV      + +G+G++ P     PP G  PPPPPP
Sbjct: 454 TPVGSGVYR----LHQGKGMMPP-----PPMGMMPPPPPP 484


>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
          Length = 638

 Score = 81.6 bits (200), Expect = 9e-16
 Identities = 67/238 (28%), Positives = 106/238 (44%), Gaps = 45/238 (18%)

Query: 55  KLGQKVLIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRK 114
           ++  KV+IP  ++P+ NFVG L+GPRGN+LK +++E   K+ I GKGS+    KE ++ +
Sbjct: 135 RVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGKGSV----KEGKVGR 190

Query: 115 SGEAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFL-----IPDYNDEIRQAQLQ 169
                    ++ LH L+      A     +  A+E+I+  L      P+  +++R+ QL+
Sbjct: 191 KDGQMLPGEDEPLHALV-----TANTMENVKKAVEQIRNILKQGIETPEDQNDLRKMQLR 245

Query: 170 ELTYLNGGSENADVPVVRGKPTLRTRGVPAPAITRGRGGV--------TARP-------- 213
           EL  LNG     D  ++R   +  TR +    +    GG           RP        
Sbjct: 246 ELARLNGTLREDDNRILRPWQSSETRSITNTTVCTKCGGAGHIASDCKFQRPGDPQSAQD 305

Query: 214 --------VGVVVPRG-TPTPRGVLSTRGPVSRGRGLLTPRARGVPPTGYRPPPPPPT 262
                   + ++   G  P P  V ST GP +      TP A    P      PPPP+
Sbjct: 306 KARMDKEYLSLMAELGEAPVPASVGSTSGPAT------TPLASAPRPAAPANNPPPPS 357



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 16/40 (40%), Positives = 21/40 (52%), Gaps = 9/40 (22%)

Query: 222 TPTPRGVLSTRGPVSRGRGLLTPRARGVPPTGYRPPPPPP 261
           TP   GV      + +G+G++ P     PP G  PPPPPP
Sbjct: 454 TPVGSGVYR----LHQGKGMMPP-----PPMGMMPPPPPP 484



 Score = 28.9 bits (63), Expect = 7.1
 Identities = 18/61 (29%), Positives = 23/61 (37%), Gaps = 3/61 (4%)

Query: 210 TARPVGVVVPRGTPTPRGVLSTRGPVSRGRGLLTPRARGVPPT---GYRPPPPPPTQETY 266
           T+   G + P          S   P  +G   + P   GV P    G  PPPPPP   + 
Sbjct: 534 TSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSA 593

Query: 267 G 267
           G
Sbjct: 594 G 594


>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
          Length = 639

 Score = 81.6 bits (200), Expect = 9e-16
 Identities = 67/238 (28%), Positives = 106/238 (44%), Gaps = 45/238 (18%)

Query: 55  KLGQKVLIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRK 114
           ++  KV+IP  ++P+ NFVG L+GPRGN+LK +++E   K+ I GKGS+    KE ++ +
Sbjct: 135 RVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGKGSV----KEGKVGR 190

Query: 115 SGEAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFL-----IPDYNDEIRQAQLQ 169
                    ++ LH L+      A     +  A+E+I+  L      P+  +++R+ QL+
Sbjct: 191 KDGQMLPGEDEPLHALV-----TANTMENVKKAVEQIRNILKQGIETPEDQNDLRKMQLR 245

Query: 170 ELTYLNGGSENADVPVVRGKPTLRTRGVPAPAITRGRGGV--------TARP-------- 213
           EL  LNG     D  ++R   +  TR +    +    GG           RP        
Sbjct: 246 ELARLNGTLREDDNRILRPWQSSETRSITNTTVCTKCGGAGHIASDCKFQRPGDPQSAQD 305

Query: 214 --------VGVVVPRG-TPTPRGVLSTRGPVSRGRGLLTPRARGVPPTGYRPPPPPPT 262
                   + ++   G  P P  V ST GP +      TP A    P      PPPP+
Sbjct: 306 KARMDKEYLSLMAELGEAPVPASVGSTSGPAT------TPLASAPRPAAPANNPPPPS 357



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 16/40 (40%), Positives = 21/40 (52%), Gaps = 9/40 (22%)

Query: 222 TPTPRGVLSTRGPVSRGRGLLTPRARGVPPTGYRPPPPPP 261
           TP   GV      + +G+G++ P     PP G  PPPPPP
Sbjct: 454 TPVGSGVYR----LHQGKGMMPP-----PPMGMMPPPPPP 484



 Score = 28.9 bits (63), Expect = 7.1
 Identities = 18/61 (29%), Positives = 23/61 (37%), Gaps = 3/61 (4%)

Query: 210 TARPVGVVVPRGTPTPRGVLSTRGPVSRGRGLLTPRARGVPPT---GYRPPPPPPTQETY 266
           T+   G + P          S   P  +G   + P   GV P    G  PPPPPP   + 
Sbjct: 534 TSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSA 593

Query: 267 G 267
           G
Sbjct: 594 G 594


>gi|56699409 RNA binding motif protein, X-linked [Homo sapiens]
          Length = 391

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 53/176 (30%), Positives = 66/176 (37%), Gaps = 31/176 (17%)

Query: 175 NGGSENADVPVVRGKPTLRTRGVPAPAITRGRGGVTARPVGVVVPRGTPTPRGVLSTRGP 234
           N  S    +PV RG P     G P P  +               P G       +  R P
Sbjct: 139 NMSSSRGPLPVKRGPPP--RSGGPPPKRS--------------APSGPVRSSSGMGGRAP 182

Query: 235 VSRGRGLLTPRARGVPPTGYRPPPPPPTQETYGEYDYDDGYGT--AYDEQSY-DSYDNSY 291
           VSRGR      + G PP   R  P P  ++ Y     DDGY T  +Y  + Y  S D   
Sbjct: 183 VSRGRD-----SYGGPP---RREPLPSRRDVYLS-PRDDGYSTKDSYSSRDYPSSRDTRD 233

Query: 292 STPAQSGADYYDYGHGLSEETYDSYGQEEWTN-SRHKAPSARTAKGVYRD--QPYG 344
             P      Y DYGH  S + Y S G  +     R +  S   + G YRD  + YG
Sbjct: 234 YAPPPRDYTYRDYGHSSSRDDYPSRGYSDRDGYGRDRDYSDHPSGGSYRDSYESYG 289


>gi|242117971 RNA binding motif protein, X-linked-like 1 [Homo
           sapiens]
          Length = 390

 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 52/176 (29%), Positives = 67/176 (38%), Gaps = 31/176 (17%)

Query: 175 NGGSENADVPVVRGKPTLRTRGVPAPAITRGRGGVTARPVGVVVPRGTPTPRGVLSTRGP 234
           N  S    +PV RG P     G P+P  +               P G       +  R P
Sbjct: 139 NMSSSRGPLPVKRGPPP--RSGGPSPKRS--------------APSGLVRSSSGMGGRAP 182

Query: 235 VSRGRGLLTPRARGVPPTGYRPPPPPPTQETYGEYDYDDGYGT--AYDEQSY-DSYDNSY 291
           +SRGR      + G PP   R  P P  ++ Y     DDGY T  +Y  + Y  S D   
Sbjct: 183 LSRGRD-----SYGGPP---RREPLPSRRDVYLS-PRDDGYSTKDSYSSRDYPSSRDTRD 233

Query: 292 STPAQSGADYYDYGHGLSEETYDSYGQEEWTN-SRHKAPSARTAKGVYRD--QPYG 344
             P      Y DYGH  S + Y S G  +     R +  S   + G YRD  + YG
Sbjct: 234 YAPPPRDYTYRDYGHSSSRDDYPSRGYGDRDGYGRDRDYSDHPSGGSYRDSYESYG 289


>gi|21361809 RNA binding motif protein, X-linked-like 1 [Homo
           sapiens]
          Length = 390

 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 52/176 (29%), Positives = 67/176 (38%), Gaps = 31/176 (17%)

Query: 175 NGGSENADVPVVRGKPTLRTRGVPAPAITRGRGGVTARPVGVVVPRGTPTPRGVLSTRGP 234
           N  S    +PV RG P     G P+P  +               P G       +  R P
Sbjct: 139 NMSSSRGPLPVKRGPPP--RSGGPSPKRS--------------APSGLVRSSSGMGGRAP 182

Query: 235 VSRGRGLLTPRARGVPPTGYRPPPPPPTQETYGEYDYDDGYGT--AYDEQSY-DSYDNSY 291
           +SRGR      + G PP   R  P P  ++ Y     DDGY T  +Y  + Y  S D   
Sbjct: 183 LSRGRD-----SYGGPP---RREPLPSRRDVYLS-PRDDGYSTKDSYSSRDYPSSRDTRD 233

Query: 292 STPAQSGADYYDYGHGLSEETYDSYGQEEWTN-SRHKAPSARTAKGVYRD--QPYG 344
             P      Y DYGH  S + Y S G  +     R +  S   + G YRD  + YG
Sbjct: 234 YAPPPRDYTYRDYGHSSSRDDYPSRGYGDRDGYGRDRDYSDHPSGGSYRDSYESYG 289


>gi|128485756 hexaribonucleotide binding protein 3 [Homo sapiens]
          Length = 312

 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 33/84 (39%), Positives = 40/84 (47%), Gaps = 10/84 (11%)

Query: 223 PTPRGVLSTRGPVSRGRGLLTPRARGVPPTGYRPPPPPPTQETYGEYDYDDGYGTAYDEQ 282
           PT    ++ RG   RGRG      R V  T +R  PPPP   TYG   Y DG+  A    
Sbjct: 214 PTTGTAVAYRGAHLRGRG------RAVYNT-FRAAPPPPPIPTYGAVVYQDGFYGAEIYG 266

Query: 283 SYDSYDNSYSTPAQSGADYYD-YG 305
            Y +Y   Y+ PA + A Y D YG
Sbjct: 267 GYAAY--RYAQPAAAAAAYSDSYG 288



 Score = 28.9 bits (63), Expect = 7.1
 Identities = 17/57 (29%), Positives = 25/57 (43%), Gaps = 8/57 (14%)

Query: 244 PRARGVPPTGYRPPPPPPTQETYGEYDYDDGYGTAYDEQSYDSYDNSYSTPAQSGAD 300
           P   G+P   Y PPPP PTQ+  G+      +G          Y  + + P Q G++
Sbjct: 13  PPQNGIPAE-YAPPPPHPTQDYSGQTPVPTEHGMTL-------YTPAQTHPEQPGSE 61


>gi|238624257 insulin-like growth factor 2 mRNA binding protein 1
           isoform 2 [Homo sapiens]
          Length = 438

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 19/67 (28%), Positives = 39/67 (58%)

Query: 31  IEKFQKGEGKDEEKYIDVVINKNMKLGQKVLIPVKQFPKFNFVGKLLGPRGNSLKRLQEE 90
           +E  ++   + E   ++V  +   +  Q   +P+K     NFVG+L+G  G +LK+++++
Sbjct: 107 VENCEQVNTESETAVVNVTYSNREQTRQADEVPLKILAHNNFVGRLIGKEGRNLKKVEQD 166

Query: 91  TLTKMSI 97
           T TK++I
Sbjct: 167 TETKITI 173


>gi|30795212 insulin-like growth factor 2 mRNA binding protein 3
           [Homo sapiens]
          Length = 579

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 27/89 (30%), Positives = 45/89 (50%), Gaps = 20/89 (22%)

Query: 62  IPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKM---------------SILGKGSMRDK 106
           IP+K     NFVG+L+G  G +LK+++++T TK+               +I  KG++   
Sbjct: 277 IPLKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETC 336

Query: 107 AKEEE-----LRKSGEAKYFHLNDDLHVL 130
           AK EE     +R+S E     +N   H++
Sbjct: 337 AKAEEEIMKKIRESYENDIASMNLQAHLI 365


>gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a
           [Homo sapiens]
          Length = 464

 Score = 38.1 bits (87), Expect = 0.012
 Identities = 44/148 (29%), Positives = 57/148 (38%), Gaps = 35/148 (23%)

Query: 195 RGVPAPAITRGRGGVTARPVGVVVPRGTPTPRG------VLSTRGPVSR-----GRGLLT 243
           RG P     RGRGG    P G     G P P        +   RGP        GRG   
Sbjct: 247 RGRPVGFPMRGRGGFDRMPPG---RGGRPMPPSRRDYDDMSPRRGPPPPPPGRGGRG--G 301

Query: 244 PRARGVPPTGYRPPPPPPTQETYGEYDYDDGYGTAYD-------EQSYDSYDNSYSTPAQ 296
            RAR +P     PPPPPP       YD     G  YD       ++++DS  +++S P++
Sbjct: 302 SRARNLP----LPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAIDTWS-PSE 356

Query: 297 -------SGADYYDYGHGLSEETYDSYG 317
                   G   YDY +     +Y   G
Sbjct: 357 WQMAYEPQGGSGYDYSYAGGRGSYGDLG 384


>gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b
           [Homo sapiens]
          Length = 463

 Score = 38.1 bits (87), Expect = 0.012
 Identities = 44/148 (29%), Positives = 57/148 (38%), Gaps = 35/148 (23%)

Query: 195 RGVPAPAITRGRGGVTARPVGVVVPRGTPTPRG------VLSTRGPVSR-----GRGLLT 243
           RG P     RGRGG    P G     G P P        +   RGP        GRG   
Sbjct: 247 RGRPVGFPMRGRGGFDRMPPG---RGGRPMPPSRRDYDDMSPRRGPPPPPPGRGGRG--G 301

Query: 244 PRARGVPPTGYRPPPPPPTQETYGEYDYDDGYGTAYD-------EQSYDSYDNSYSTPAQ 296
            RAR +P     PPPPPP       YD     G  YD       ++++DS  +++S P++
Sbjct: 302 SRARNLP----LPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAIDTWS-PSE 356

Query: 297 -------SGADYYDYGHGLSEETYDSYG 317
                   G   YDY +     +Y   G
Sbjct: 357 WQMAYEPQGGSGYDYSYAGGRGSYGDLG 384


>gi|14165437 heterogeneous nuclear ribonucleoprotein K isoform a
           [Homo sapiens]
          Length = 464

 Score = 38.1 bits (87), Expect = 0.012
 Identities = 44/148 (29%), Positives = 57/148 (38%), Gaps = 35/148 (23%)

Query: 195 RGVPAPAITRGRGGVTARPVGVVVPRGTPTPRG------VLSTRGPVSR-----GRGLLT 243
           RG P     RGRGG    P G     G P P        +   RGP        GRG   
Sbjct: 247 RGRPVGFPMRGRGGFDRMPPG---RGGRPMPPSRRDYDDMSPRRGPPPPPPGRGGRG--G 301

Query: 244 PRARGVPPTGYRPPPPPPTQETYGEYDYDDGYGTAYD-------EQSYDSYDNSYSTPAQ 296
            RAR +P     PPPPPP       YD     G  YD       ++++DS  +++S P++
Sbjct: 302 SRARNLP----LPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAIDTWS-PSE 356

Query: 297 -------SGADYYDYGHGLSEETYDSYG 317
                   G   YDY +     +Y   G
Sbjct: 357 WQMAYEPQGGSGYDYSYAGGRGSYGDLG 384


>gi|215272410 ataxin 2-binding protein 1 isoform 5 [Homo sapiens]
          Length = 370

 Score = 37.7 bits (86), Expect = 0.015
 Identities = 35/108 (32%), Positives = 43/108 (39%), Gaps = 10/108 (9%)

Query: 208 GVTARPVGVVVPRGTPTPRGVLST--RGPVSRGRGLLTPRARGVPPTGYRPPPPPPTQET 265
           G    P    VP G P P    +   RG   RGRG      R V  T +R   PPP    
Sbjct: 216 GAVYSPEFYAVP-GFPYPAATAAAAYRGAHLRGRG------RTVYNT-FRAAAPPPPIPA 267

Query: 266 YGEYDYDDGYGTAYDEQSYDSYDNSYSTPAQSGADYYDYGHGLSEETY 313
           YG   Y DG+  A     Y +Y  +  TPA + A    YG   + + Y
Sbjct: 268 YGGVVYQDGFYGADIYGGYAAYRYAQPTPATAAAYSDSYGRVYAADPY 315


>gi|56237027 insulin-like growth factor 2 mRNA binding protein 1
           isoform 1 [Homo sapiens]
          Length = 577

 Score = 37.7 bits (86), Expect = 0.015
 Identities = 15/36 (41%), Positives = 27/36 (75%)

Query: 62  IPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSI 97
           +P+K     NFVG+L+G  G +LK+++++T TK++I
Sbjct: 277 VPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITI 312


>gi|38150007 small nuclear ribonucleoprotein polypeptide B/B'
           isoform B' [Homo sapiens]
          Length = 240

 Score = 37.7 bits (86), Expect = 0.015
 Identities = 30/77 (38%), Positives = 36/77 (46%), Gaps = 15/77 (19%)

Query: 186 VRGKPTLRTRGVPAPAITRGRGGVTARPVGVVVPRGTPTPRGVLSTRGP---VSRGRGLL 242
           + G PT    G   P    GRG   A P G++ P     P G+    GP   +  GRG  
Sbjct: 161 IAGAPTQYPPGRGGPPPPMGRG---APPPGMMGP-----PPGMRPPMGPPMGIPPGRG-- 210

Query: 243 TPRARGVPPTGYRPPPP 259
           TP   G+PP G RPPPP
Sbjct: 211 TPM--GMPPPGMRPPPP 225



 Score = 35.4 bits (80), Expect = 0.076
 Identities = 38/125 (30%), Positives = 46/125 (36%), Gaps = 31/125 (24%)

Query: 164 RQAQLQE-----LTYLNGGSENADVPVVRGKPTLRTRGVPAPAITRGRGGVTARPVGVVV 218
           +QA+ +E     L  L G  EN     V G P   T     P      G    R  G  +
Sbjct: 57  KQAEREEKRVLGLVLLRG--ENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGI 114

Query: 219 PRGTPTPRGVLSTRGPVSRGRG-----LLTPRARGV--------------PPTGYRP--- 256
           P G P P+      GPV RG G     ++TP+ RG                PT Y P   
Sbjct: 115 PAGVPMPQAPAGLAGPV-RGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRG 173

Query: 257 -PPPP 260
            PPPP
Sbjct: 174 GPPPP 178



 Score = 32.0 bits (71), Expect = 0.84
 Identities = 26/72 (36%), Positives = 28/72 (38%), Gaps = 6/72 (8%)

Query: 195 RGVPAPA----ITRGRGGVTARPVGVVVP-RGTPTPRGVLSTRGPVSRGRGLLTPRARGV 249
           RGV  P+      +GRG V A          G PT         P   GRG   P   G 
Sbjct: 132 RGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMG- 190

Query: 250 PPTGYRPPPPPP 261
           PP G RPP  PP
Sbjct: 191 PPPGMRPPMGPP 202


>gi|4507125 small nuclear ribonucleoprotein polypeptide B/B' isoform
           B [Homo sapiens]
          Length = 231

 Score = 37.7 bits (86), Expect = 0.015
 Identities = 30/77 (38%), Positives = 36/77 (46%), Gaps = 15/77 (19%)

Query: 186 VRGKPTLRTRGVPAPAITRGRGGVTARPVGVVVPRGTPTPRGVLSTRGP---VSRGRGLL 242
           + G PT    G   P    GRG   A P G++ P     P G+    GP   +  GRG  
Sbjct: 161 IAGAPTQYPPGRGGPPPPMGRG---APPPGMMGP-----PPGMRPPMGPPMGIPPGRG-- 210

Query: 243 TPRARGVPPTGYRPPPP 259
           TP   G+PP G RPPPP
Sbjct: 211 TPM--GMPPPGMRPPPP 225



 Score = 35.4 bits (80), Expect = 0.076
 Identities = 38/125 (30%), Positives = 46/125 (36%), Gaps = 31/125 (24%)

Query: 164 RQAQLQE-----LTYLNGGSENADVPVVRGKPTLRTRGVPAPAITRGRGGVTARPVGVVV 218
           +QA+ +E     L  L G  EN     V G P   T     P      G    R  G  +
Sbjct: 57  KQAEREEKRVLGLVLLRG--ENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGI 114

Query: 219 PRGTPTPRGVLSTRGPVSRGRG-----LLTPRARGV--------------PPTGYRP--- 256
           P G P P+      GPV RG G     ++TP+ RG                PT Y P   
Sbjct: 115 PAGVPMPQAPAGLAGPV-RGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRG 173

Query: 257 -PPPP 260
            PPPP
Sbjct: 174 GPPPP 178



 Score = 32.0 bits (71), Expect = 0.84
 Identities = 26/72 (36%), Positives = 28/72 (38%), Gaps = 6/72 (8%)

Query: 195 RGVPAPA----ITRGRGGVTARPVGVVVP-RGTPTPRGVLSTRGPVSRGRGLLTPRARGV 249
           RGV  P+      +GRG V A          G PT         P   GRG   P   G 
Sbjct: 132 RGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMG- 190

Query: 250 PPTGYRPPPPPP 261
           PP G RPP  PP
Sbjct: 191 PPPGMRPPMGPP 202


>gi|156151396 heterogeneous nuclear ribonucleoprotein R isoform 3
           [Homo sapiens]
          Length = 535

 Score = 37.7 bits (86), Expect = 0.015
 Identities = 39/133 (29%), Positives = 55/133 (41%), Gaps = 17/133 (12%)

Query: 190 PTLRTRGVPAPAITRGRGGVTARPVGVVVPRGTPTPRGVLSTRGPVSRGRGLLTPRARGV 249
           P  R RG P P   RGR G + R   +  PRG+   RG     GP  + RG  +  +R  
Sbjct: 415 PPPRGRGAPPP---RGRAGYSQRGAPLGPPRGSRGGRG-----GPAQQQRGRGSRGSR-- 464

Query: 250 PPTGYRPPPPPPTQETYGEYDYDDGYGTAYDEQSYDSYDNSYSTPAQSGADY---YDYGH 306
              G R       ++  G    D       ++Q++ S   +   P Q G DY   Y Y +
Sbjct: 465 ---GNRGGNVGGKRKADGYNQPDSKRRQTNNQQNWGSQPIA-QQPLQQGGDYSGNYGYNN 520

Query: 307 GLSEETYDSYGQE 319
              E   D+YGQ+
Sbjct: 521 DNQEFYQDTYGQQ 533



 Score = 33.5 bits (75), Expect = 0.29
 Identities = 22/62 (35%), Positives = 27/62 (43%), Gaps = 8/62 (12%)

Query: 254 YRPPP--PPPTQETYGEYDYDDGYGTAYDEQSYDSYDNSYSTPAQSGADYYDYGHGLSEE 311
           Y PPP  PPP +   G      GYG   D   Y+ Y + Y      G DY+DY  G  + 
Sbjct: 338 YHPPPRMPPPIRGR-GRGGGRGGYGYPPDYYGYEDYYDDY-----YGYDYHDYRGGYEDP 391

Query: 312 TY 313
            Y
Sbjct: 392 YY 393


>gi|156151394 heterogeneous nuclear ribonucleoprotein R isoform 1
           [Homo sapiens]
          Length = 636

 Score = 37.7 bits (86), Expect = 0.015
 Identities = 39/133 (29%), Positives = 55/133 (41%), Gaps = 17/133 (12%)

Query: 190 PTLRTRGVPAPAITRGRGGVTARPVGVVVPRGTPTPRGVLSTRGPVSRGRGLLTPRARGV 249
           P  R RG P P   RGR G + R   +  PRG+   RG     GP  + RG  +  +R  
Sbjct: 516 PPPRGRGAPPP---RGRAGYSQRGAPLGPPRGSRGGRG-----GPAQQQRGRGSRGSR-- 565

Query: 250 PPTGYRPPPPPPTQETYGEYDYDDGYGTAYDEQSYDSYDNSYSTPAQSGADY---YDYGH 306
              G R       ++  G    D       ++Q++ S   +   P Q G DY   Y Y +
Sbjct: 566 ---GNRGGNVGGKRKADGYNQPDSKRRQTNNQQNWGSQPIA-QQPLQQGGDYSGNYGYNN 621

Query: 307 GLSEETYDSYGQE 319
              E   D+YGQ+
Sbjct: 622 DNQEFYQDTYGQQ 634



 Score = 33.5 bits (75), Expect = 0.29
 Identities = 22/62 (35%), Positives = 27/62 (43%), Gaps = 8/62 (12%)

Query: 254 YRPPP--PPPTQETYGEYDYDDGYGTAYDEQSYDSYDNSYSTPAQSGADYYDYGHGLSEE 311
           Y PPP  PPP +   G      GYG   D   Y+ Y + Y      G DY+DY  G  + 
Sbjct: 439 YHPPPRMPPPIRGR-GRGGGRGGYGYPPDYYGYEDYYDDY-----YGYDYHDYRGGYEDP 492

Query: 312 TY 313
            Y
Sbjct: 493 YY 494


>gi|156151392 heterogeneous nuclear ribonucleoprotein R isoform 4
           [Homo sapiens]
          Length = 532

 Score = 37.7 bits (86), Expect = 0.015
 Identities = 39/133 (29%), Positives = 55/133 (41%), Gaps = 17/133 (12%)

Query: 190 PTLRTRGVPAPAITRGRGGVTARPVGVVVPRGTPTPRGVLSTRGPVSRGRGLLTPRARGV 249
           P  R RG P P   RGR G + R   +  PRG+   RG     GP  + RG  +  +R  
Sbjct: 412 PPPRGRGAPPP---RGRAGYSQRGAPLGPPRGSRGGRG-----GPAQQQRGRGSRGSR-- 461

Query: 250 PPTGYRPPPPPPTQETYGEYDYDDGYGTAYDEQSYDSYDNSYSTPAQSGADY---YDYGH 306
              G R       ++  G    D       ++Q++ S   +   P Q G DY   Y Y +
Sbjct: 462 ---GNRGGNVGGKRKADGYNQPDSKRRQTNNQQNWGSQPIA-QQPLQQGGDYSGNYGYNN 517

Query: 307 GLSEETYDSYGQE 319
              E   D+YGQ+
Sbjct: 518 DNQEFYQDTYGQQ 530



 Score = 33.5 bits (75), Expect = 0.29
 Identities = 22/62 (35%), Positives = 27/62 (43%), Gaps = 8/62 (12%)

Query: 254 YRPPP--PPPTQETYGEYDYDDGYGTAYDEQSYDSYDNSYSTPAQSGADYYDYGHGLSEE 311
           Y PPP  PPP +   G      GYG   D   Y+ Y + Y      G DY+DY  G  + 
Sbjct: 335 YHPPPRMPPPIRGR-GRGGGRGGYGYPPDYYGYEDYYDDY-----YGYDYHDYRGGYEDP 388

Query: 312 TY 313
            Y
Sbjct: 389 YY 390


>gi|5031755 heterogeneous nuclear ribonucleoprotein R isoform 2
           [Homo sapiens]
          Length = 633

 Score = 37.7 bits (86), Expect = 0.015
 Identities = 39/133 (29%), Positives = 55/133 (41%), Gaps = 17/133 (12%)

Query: 190 PTLRTRGVPAPAITRGRGGVTARPVGVVVPRGTPTPRGVLSTRGPVSRGRGLLTPRARGV 249
           P  R RG P P   RGR G + R   +  PRG+   RG     GP  + RG  +  +R  
Sbjct: 513 PPPRGRGAPPP---RGRAGYSQRGAPLGPPRGSRGGRG-----GPAQQQRGRGSRGSR-- 562

Query: 250 PPTGYRPPPPPPTQETYGEYDYDDGYGTAYDEQSYDSYDNSYSTPAQSGADY---YDYGH 306
              G R       ++  G    D       ++Q++ S   +   P Q G DY   Y Y +
Sbjct: 563 ---GNRGGNVGGKRKADGYNQPDSKRRQTNNQQNWGSQPIA-QQPLQQGGDYSGNYGYNN 618

Query: 307 GLSEETYDSYGQE 319
              E   D+YGQ+
Sbjct: 619 DNQEFYQDTYGQQ 631



 Score = 33.5 bits (75), Expect = 0.29
 Identities = 22/62 (35%), Positives = 27/62 (43%), Gaps = 8/62 (12%)

Query: 254 YRPPP--PPPTQETYGEYDYDDGYGTAYDEQSYDSYDNSYSTPAQSGADYYDYGHGLSEE 311
           Y PPP  PPP +   G      GYG   D   Y+ Y + Y      G DY+DY  G  + 
Sbjct: 436 YHPPPRMPPPIRGR-GRGGGRGGYGYPPDYYGYEDYYDDY-----YGYDYHDYRGGYEDP 489

Query: 312 TY 313
            Y
Sbjct: 490 YY 491


>gi|4826974 RNA binding motif protein, Y-linked, family 1, member A1
           [Homo sapiens]
          Length = 496

 Score = 37.4 bits (85), Expect = 0.020
 Identities = 27/93 (29%), Positives = 35/93 (37%), Gaps = 6/93 (6%)

Query: 254 YRPPPPPPTQETYGEYDYDDGYGTAYDEQSYDSYDNSYSTPAQSGADYYDYGHGLSEETY 313
           Y PP        YG    D+ Y   Y  +        Y+ P++ G  Y DYGH    E+Y
Sbjct: 268 YAPPSRGHAYRDYGHSRRDESYSRGYRNRRSSRETREYAPPSR-GHGYRDYGHSRRHESY 326

Query: 314 DSYGQEEWTNSRHKAPSARTAKGVYRDQPYGRY 346
            S G     +SR      R     +RD  Y  Y
Sbjct: 327 -SRGYRNHPSSR----ETRDYAPPHRDYAYRDY 354



 Score = 34.7 bits (78), Expect = 0.13
 Identities = 28/85 (32%), Positives = 36/85 (42%), Gaps = 9/85 (10%)

Query: 269 YDYDDGYGTAYDEQSYDSYDNSYST-------PAQSGADYYDYGHGLSEETYDSYGQEEW 321
           Y Y D   +  DE S   Y N  S+       P   G  Y DYGH   +E+Y S G    
Sbjct: 238 YAYRDNGHSNRDEHSSRGYRNHRSSRETRDYAPPSRGHAYRDYGHSRRDESY-SRGYRNR 296

Query: 322 TNSRHKAPSARTAKG-VYRDQPYGR 345
            +SR     A  ++G  YRD  + R
Sbjct: 297 RSSRETREYAPPSRGHGYRDYGHSR 321


>gi|54873602 hypothetical protein LOC220382 [Homo sapiens]
          Length = 426

 Score = 37.4 bits (85), Expect = 0.020
 Identities = 30/80 (37%), Positives = 36/80 (45%), Gaps = 14/80 (17%)

Query: 202 ITRGRGGVTAR-PVGVVVPRGTPTPRGVLSTRGPVSRGRGLLTPRARGVPPTGYRPPPPP 260
           +T  RGG+T   P+  + P    +P G          GRG L   A   P     PPPPP
Sbjct: 337 LTAPRGGLTLNEPLSPLYPAAADSPGG--------EDGRGHLASFAPFFPDCAL-PPPPP 387

Query: 261 PTQETYGEYDYDDGYG-TAY 279
           P Q +   YDY  GY  TAY
Sbjct: 388 PHQVS---YDYSAGYSRTAY 404


>gi|56090527 RNA binding motif protein, Y-linked, family 1, member E
           [Homo sapiens]
          Length = 496

 Score = 37.4 bits (85), Expect = 0.020
 Identities = 27/93 (29%), Positives = 35/93 (37%), Gaps = 6/93 (6%)

Query: 254 YRPPPPPPTQETYGEYDYDDGYGTAYDEQSYDSYDNSYSTPAQSGADYYDYGHGLSEETY 313
           Y PP        YG    D+ Y   Y  +        Y+ P++ G  Y DYGH    E+Y
Sbjct: 268 YAPPSRGHAYRDYGHSRRDESYSRGYRNRRSSRETREYAPPSR-GHGYRDYGHSRRHESY 326

Query: 314 DSYGQEEWTNSRHKAPSARTAKGVYRDQPYGRY 346
            S G     +SR      R     +RD  Y  Y
Sbjct: 327 -SRGYRNHPSSR----ETRDYAPPHRDYAYRDY 354



 Score = 34.7 bits (78), Expect = 0.13
 Identities = 28/85 (32%), Positives = 36/85 (42%), Gaps = 9/85 (10%)

Query: 269 YDYDDGYGTAYDEQSYDSYDNSYST-------PAQSGADYYDYGHGLSEETYDSYGQEEW 321
           Y Y D   +  DE S   Y N  S+       P   G  Y DYGH   +E+Y S G    
Sbjct: 238 YAYRDNGHSNRDEHSSRGYRNHRSSRETRDYAPPSRGHAYRDYGHSRRDESY-SRGYRNR 296

Query: 322 TNSRHKAPSARTAKG-VYRDQPYGR 345
            +SR     A  ++G  YRD  + R
Sbjct: 297 RSSRETREYAPPSRGHGYRDYGHSR 321


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.135    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,510,583
Number of Sequences: 37866
Number of extensions: 1013413
Number of successful extensions: 6959
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 77
Number of HSP's successfully gapped in prelim test: 287
Number of HSP's that attempted gapping in prelim test: 5666
Number of HSP's gapped (non-prelim): 1241
length of query: 346
length of database: 18,247,518
effective HSP length: 103
effective length of query: 243
effective length of database: 14,347,320
effective search space: 3486398760
effective search space used: 3486398760
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.