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Search of human proteins with 5729877
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5729877 heat shock 70kDa protein 8 isoform 1 [Homo sapiens]
(646 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5729877 heat shock 70kDa protein 8 isoform 1 [Homo sapiens] 1274 0.0
gi|13676857 heat shock 70kDa protein 2 [Homo sapiens] 1109 0.0
gi|167466173 heat shock 70kDa protein 1B [Homo sapiens] 1103 0.0
gi|194248072 heat shock 70kDa protein 1A [Homo sapiens] 1103 0.0
gi|124256496 heat shock 70kDa protein 1-like [Homo sapiens] 1067 0.0
gi|34419635 heat shock 70kDa protein 6 (HSP70B') [Homo sapiens] 1018 0.0
gi|24234686 heat shock 70kDa protein 8 isoform 2 [Homo sapiens] 912 0.0
gi|16507237 heat shock 70kDa protein 5 [Homo sapiens] 803 0.0
gi|24234688 heat shock 70kDa protein 9 precursor [Homo sapiens] 576 e-164
gi|82880658 heat shock 70kDa protein 14 isoform 1 [Homo sapiens] 310 2e-84
gi|38327039 heat shock 70kDa protein 4 [Homo sapiens] 288 8e-78
gi|48928056 heat shock protein 70kDa family member 13 precursor ... 276 3e-74
gi|42544159 heat shock 105kD [Homo sapiens] 271 1e-72
gi|31541941 heat shock 70kDa protein 4-like [Homo sapiens] 268 9e-72
gi|195976805 hypoxia up-regulated 1 precursor [Homo sapiens] 227 3e-59
gi|5453832 hypoxia up-regulated 1 precursor [Homo sapiens] 227 3e-59
gi|38348298 ankyrin repeat domain 45 [Homo sapiens] 47 5e-05
gi|9910266 kinesin family member 15 [Homo sapiens] 44 6e-04
gi|32967605 bromodomain adjacent to zinc finger domain, 1A isofo... 40 0.007
gi|32967603 bromodomain adjacent to zinc finger domain, 1A isofo... 40 0.007
gi|55770834 centromere protein F [Homo sapiens] 39 0.015
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 39 0.019
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 39 0.019
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 39 0.019
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 39 0.019
gi|19923193 heat shock 70kD protein binding protein [Homo sapiens] 39 0.019
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 38 0.025
gi|34878777 ring finger protein 20 [Homo sapiens] 37 0.043
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 37 0.074
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 37 0.074
>gi|5729877 heat shock 70kDa protein 8 isoform 1 [Homo sapiens]
Length = 646
Score = 1274 bits (3297), Expect = 0.0
Identities = 646/646 (100%), Positives = 646/646 (100%)
Query: 1 MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA 60
MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA
Sbjct: 1 MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA 60
Query: 61 MNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVS 120
MNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVS
Sbjct: 61 MNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVS 120
Query: 121 SMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAA 180
SMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAA
Sbjct: 121 SMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAA 180
Query: 181 IAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH 240
IAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH
Sbjct: 181 IAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH 240
Query: 241 FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRA 300
FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRA
Sbjct: 241 FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRA 300
Query: 301 RFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELN 360
RFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELN
Sbjct: 301 RFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELN 360
Query: 361 KSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTI 420
KSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTI
Sbjct: 361 KSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTI 420
Query: 421 PTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDI 480
PTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDI
Sbjct: 421 PTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDI 480
Query: 481 DANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKN 540
DANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKN
Sbjct: 481 DANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKN 540
Query: 541 SLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELE 600
SLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELE
Sbjct: 541 SLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELE 600
Query: 601 KVCNPIITKLYQSAGGMPGGMPGGFPGGGAPPSGGASSGPTIEEVD 646
KVCNPIITKLYQSAGGMPGGMPGGFPGGGAPPSGGASSGPTIEEVD
Sbjct: 601 KVCNPIITKLYQSAGGMPGGMPGGFPGGGAPPSGGASSGPTIEEVD 646
>gi|13676857 heat shock 70kDa protein 2 [Homo sapiens]
Length = 639
Score = 1109 bits (2868), Expect = 0.0
Identities = 558/647 (86%), Positives = 601/647 (92%), Gaps = 12/647 (1%)
Query: 2 SKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAM 61
++GPA+GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAM
Sbjct: 3 ARGPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAM 62
Query: 62 NPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSS 121
NPTNT+FDAKRLIGR+F+DA VQSDMKHWPF VV++ G+PKVQVEYKGETK+F+PEE+SS
Sbjct: 63 NPTNTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKGETKTFFPEEISS 122
Query: 122 MVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAI 181
MVLTKMKEIAEAYLG V +AV+TVPAYFNDSQRQATKDAGTI GLNVLRIINEPTAAAI
Sbjct: 123 MVLTKMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAI 182
Query: 182 AYGLDKK--VGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVN 239
AYGLDKK G E+NVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMV+
Sbjct: 183 AYGLDKKGCAGGEKNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVS 242
Query: 240 HFIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITR 299
H EFKRKHKKDI NKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEG+DFYTSITR
Sbjct: 243 HLAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSITR 302
Query: 300 ARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKEL 359
ARFEELNADLFRGTL+PVEKALRDAKLDK QI +IVLVGGSTRIPKIQKLLQDFFNGKEL
Sbjct: 303 ARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKEL 362
Query: 360 NKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTT 419
NKSINPDEAVAYGAAVQAAIL GDKSENVQDLLLLDVTPLSLGIETAGGVMT LIKRNTT
Sbjct: 363 NKSINPDEAVAYGAAVQAAILIGDKSENVQDLLLLDVTPLSLGIETAGGVMTPLIKRNTT 422
Query: 420 IPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFD 479
IPTKQTQTFTTYSDNQ VL+QVYEGERAMTKDNNLLGKF+LTGIPPAPRGVPQIEVTFD
Sbjct: 423 IPTKQTQTFTTYSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPAPRGVPQIEVTFD 482
Query: 480 IDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSK 539
IDANGILNV+A DKSTGKENKITITNDKGRLSK+DI+RMVQEAE+YK+EDE RD+V++K
Sbjct: 483 IDANGILNVTAADKSTGKENKITITNDKGRLSKDDIDRMVQEAERYKSEDEANRDRVAAK 542
Query: 540 NSLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKEL 599
N+LESY +N+K TVEDEKL+GKI+++DK KILDKC E+INWLD+NQ AEK+E+EH+QKEL
Sbjct: 543 NALESYTYNIKQTVEDEKLRGKISEQDKNKILDKCQEVINWLDRNQMAEKDEYEHKQKEL 602
Query: 600 EKVCNPIITKLYQSAGGMPGGMPGGFPGGGAPPSGGASSGPTIEEVD 646
E+VCNPII+KLYQ G PGG GGG GAS GPTIEEVD
Sbjct: 603 ERVCNPIISKLYQ-------GGPGGGSGGG---GSGASGGPTIEEVD 639
>gi|167466173 heat shock 70kDa protein 1B [Homo sapiens]
Length = 641
Score = 1103 bits (2854), Expect = 0.0
Identities = 553/646 (85%), Positives = 601/646 (93%), Gaps = 5/646 (0%)
Query: 1 MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA 60
M+K A+GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA
Sbjct: 1 MAKAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA 60
Query: 61 MNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVS 120
+NP NTVFDAKRLIGR+F D VVQSDMKHWPF V+ND +PKVQV YKGETK+FYPEE+S
Sbjct: 61 LNPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGETKAFYPEEIS 120
Query: 121 SMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAA 180
SMVLTKMKEIAEAYLG VTNAV+TVPAYFNDSQRQATKDAG IAGLNVLRIINEPTAAA
Sbjct: 121 SMVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAA 180
Query: 181 IAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH 240
IAYGLD+ ERNVLIFDLGGGTFDVSILTI+DGIFEVK+TAGDTHLGGEDFDNR+VNH
Sbjct: 181 IAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNH 240
Query: 241 FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRA 300
F+ EFKRKHKKDIS+NKRAVRRLRTACERAKRTLSSSTQAS+EIDSL+EGIDFYTSITRA
Sbjct: 241 FVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRA 300
Query: 301 RFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELN 360
RFEEL +DLFR TL+PVEKALRDAKLDK+QIHD+VLVGGSTRIPK+QKLLQDFFNG++LN
Sbjct: 301 RFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLN 360
Query: 361 KSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTI 420
KSINPDEAVAYGAAVQAAIL GDKSENVQDLLLLDV PLSLG+ETAGGVMT LIKRN+TI
Sbjct: 361 KSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTI 420
Query: 421 PTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDI 480
PTKQTQ FTTYSDNQPGVLIQVYEGERAMTKDNNLLG+FEL+GIPPAPRGVPQIEVTFDI
Sbjct: 421 PTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDI 480
Query: 481 DANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKN 540
DANGILNV+A DKSTGK NKITITNDKGRLSKE+IERMVQEAEKYKAEDE QR++VS+KN
Sbjct: 481 DANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAEKYKAEDEVQRERVSAKN 540
Query: 541 SLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELE 600
+LESYAFNMK+ VEDE L+GKI++ DK+K+LDKC E+I+WLD N AEK+EFEH++KELE
Sbjct: 541 ALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRKELE 600
Query: 601 KVCNPIITKLYQSAGGMPGGMPGGFPGGGAPPSGGASSGPTIEEVD 646
+VCNPII+ LYQ AGG PG PGGF G P GG+ SGPTIEEVD
Sbjct: 601 QVCNPIISGLYQGAGG-PG--PGGF--GAQGPKGGSGSGPTIEEVD 641
>gi|194248072 heat shock 70kDa protein 1A [Homo sapiens]
Length = 641
Score = 1103 bits (2854), Expect = 0.0
Identities = 553/646 (85%), Positives = 601/646 (93%), Gaps = 5/646 (0%)
Query: 1 MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA 60
M+K A+GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA
Sbjct: 1 MAKAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA 60
Query: 61 MNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVS 120
+NP NTVFDAKRLIGR+F D VVQSDMKHWPF V+ND +PKVQV YKGETK+FYPEE+S
Sbjct: 61 LNPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGETKAFYPEEIS 120
Query: 121 SMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAA 180
SMVLTKMKEIAEAYLG VTNAV+TVPAYFNDSQRQATKDAG IAGLNVLRIINEPTAAA
Sbjct: 121 SMVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAA 180
Query: 181 IAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH 240
IAYGLD+ ERNVLIFDLGGGTFDVSILTI+DGIFEVK+TAGDTHLGGEDFDNR+VNH
Sbjct: 181 IAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNH 240
Query: 241 FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRA 300
F+ EFKRKHKKDIS+NKRAVRRLRTACERAKRTLSSSTQAS+EIDSL+EGIDFYTSITRA
Sbjct: 241 FVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRA 300
Query: 301 RFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELN 360
RFEEL +DLFR TL+PVEKALRDAKLDK+QIHD+VLVGGSTRIPK+QKLLQDFFNG++LN
Sbjct: 301 RFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLN 360
Query: 361 KSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTI 420
KSINPDEAVAYGAAVQAAIL GDKSENVQDLLLLDV PLSLG+ETAGGVMT LIKRN+TI
Sbjct: 361 KSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTI 420
Query: 421 PTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDI 480
PTKQTQ FTTYSDNQPGVLIQVYEGERAMTKDNNLLG+FEL+GIPPAPRGVPQIEVTFDI
Sbjct: 421 PTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDI 480
Query: 481 DANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKN 540
DANGILNV+A DKSTGK NKITITNDKGRLSKE+IERMVQEAEKYKAEDE QR++VS+KN
Sbjct: 481 DANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAEKYKAEDEVQRERVSAKN 540
Query: 541 SLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELE 600
+LESYAFNMK+ VEDE L+GKI++ DK+K+LDKC E+I+WLD N AEK+EFEH++KELE
Sbjct: 541 ALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRKELE 600
Query: 601 KVCNPIITKLYQSAGGMPGGMPGGFPGGGAPPSGGASSGPTIEEVD 646
+VCNPII+ LYQ AGG PG PGGF G P GG+ SGPTIEEVD
Sbjct: 601 QVCNPIISGLYQGAGG-PG--PGGF--GAQGPKGGSGSGPTIEEVD 641
>gi|124256496 heat shock 70kDa protein 1-like [Homo sapiens]
Length = 641
Score = 1067 bits (2759), Expect = 0.0
Identities = 534/645 (82%), Positives = 593/645 (91%), Gaps = 7/645 (1%)
Query: 2 SKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAM 61
+KG A+GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAM
Sbjct: 4 AKGIAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAM 63
Query: 62 NPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSS 121
NP NTVFDAKRLIGR+F+D VVQ+DMK WPF V+N+ G+PKV V YKGE K+FYPEE+SS
Sbjct: 64 NPQNTVFDAKRLIGRKFNDPVVQADMKLWPFQVINEGGKPKVLVSYKGENKAFYPEEISS 123
Query: 122 MVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAI 181
MVLTK+KE AEA+LG VTNAV+TVPAYFNDSQRQATKDAG IAGLNVLRIINEPTAAAI
Sbjct: 124 MVLTKLKETAEAFLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAI 183
Query: 182 AYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHF 241
AYGLDK ER+VLIFDLGGGTFDVSILTI+DGIFEVK+TAGDTHLGGEDFDNR+V+HF
Sbjct: 184 AYGLDKGGQGERHVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSHF 243
Query: 242 IAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRAR 301
+ EFKRKHKKDIS+NKRAVRRLRTACERAKRTLSSSTQA++EIDSLYEGIDFYTSITRAR
Sbjct: 244 VEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQANLEIDSLYEGIDFYTSITRAR 303
Query: 302 FEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNK 361
FEEL ADLFRGTL+PVEKALRDAK+DK++IHDIVLVGGSTRIPK+Q+LLQD+FNG++LNK
Sbjct: 304 FEELCADLFRGTLEPVEKALRDAKMDKAKIHDIVLVGGSTRIPKVQRLLQDYFNGRDLNK 363
Query: 362 SINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIP 421
SINPDEAVAYGAAVQAAIL GDKSE VQDLLLLDV PLSLG+ETAGGVMT LIKRN+TIP
Sbjct: 364 SINPDEAVAYGAAVQAAILMGDKSEKVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIP 423
Query: 422 TKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDID 481
TKQTQ FTTYSDNQPGVLIQVYEGERAMTKDNNLLG+F+LTGIPPAPRGVPQIEVTFDID
Sbjct: 424 TKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFDLTGIPPAPRGVPQIEVTFDID 483
Query: 482 ANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKNS 541
ANGILNV+A DKSTGK NKITITNDKGRLSKE+IERMV +AEKYKAEDE QR+K+++KN+
Sbjct: 484 ANGILNVTATDKSTGKVNKITITNDKGRLSKEEIERMVLDAEKYKAEDEVQREKIAAKNA 543
Query: 542 LESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELEK 601
LESYAFNMK+ V DE L+GKI++ DK KILDKCNE+++WL+ NQ AEK+EF+H++KELE+
Sbjct: 544 LESYAFNMKSVVSDEGLKGKISESDKNKILDKCNELLSWLEVNQLAEKDEFDHKRKELEQ 603
Query: 602 VCNPIITKLYQSAGGMPGGMPGGFPGGGAPPSGGASSGPTIEEVD 646
+CNPIITKLYQ GG G G G P G ++GPTIEEVD
Sbjct: 604 MCNPIITKLYQ------GGCTGPACGTGYVP-GRPATGPTIEEVD 641
>gi|34419635 heat shock 70kDa protein 6 (HSP70B') [Homo sapiens]
Length = 643
Score = 1018 bits (2631), Expect = 0.0
Identities = 501/641 (78%), Positives = 578/641 (90%), Gaps = 5/641 (0%)
Query: 6 AVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTN 65
AVGIDLGTTYSCVGVFQ G+VEI+ANDQGNRTTPSYVAFTDTERL+GDAAK+Q A+NP N
Sbjct: 8 AVGIDLGTTYSCVGVFQQGRVEILANDQGNRTTPSYVAFTDTERLVGDAAKSQAALNPHN 67
Query: 66 TVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSSMVLT 125
TVFDAKRLIGR+F D VQSDMKHWPF VV++ G+PKV+V Y+GE K+FYPEE+SSMVL+
Sbjct: 68 TVFDAKRLIGRKFADTTVQSDMKHWPFRVVSEGGKPKVRVCYRGEDKTFYPEEISSMVLS 127
Query: 126 KMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGL 185
KMKE AEAYLG+ V +AV+TVPAYFNDSQRQATKDAG IAGLNVLRIINEPTAAAIAYGL
Sbjct: 128 KMKETAEAYLGQPVKHAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGL 187
Query: 186 DKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFIAEF 245
D++ ERNVLIFDLGGGTFDVS+L+I+ G+FEVK+TAGDTHLGGEDFDNR+VNHF+ EF
Sbjct: 188 DRRGAGERNVLIFDLGGGTFDVSVLSIDAGVFEVKATAGDTHLGGEDFDNRLVNHFMEEF 247
Query: 246 KRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRARFEEL 305
+RKH KD+S NKRA+RRLRTACERAKRTLSSSTQA++EIDSL+EG+DFYTSITRARFEEL
Sbjct: 248 RRKHGKDLSGNKRALRRLRTACERAKRTLSSSTQATLEIDSLFEGVDFYTSITRARFEEL 307
Query: 306 NADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINP 365
+DLFR TL+PVEKALRDAKLDK+QIHD+VLVGGSTRIPK+QKLLQDFFNGKELNKSINP
Sbjct: 308 CSDLFRSTLEPVEKALRDAKLDKAQIHDVVLVGGSTRIPKVQKLLQDFFNGKELNKSINP 367
Query: 366 DEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQT 425
DEAVAYGAAVQAA+L GDK E VQDLLLLDV PLSLG+ETAGGVMT LI+RN TIPTKQT
Sbjct: 368 DEAVAYGAAVQAAVLMGDKCEKVQDLLLLDVAPLSLGLETAGGVMTTLIQRNATIPTKQT 427
Query: 426 QTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGI 485
QTFTTYSDNQPGV IQVYEGERAMTKDNNLLG+FEL+GIPPAPRGVPQIEVTFDIDANGI
Sbjct: 428 QTFTTYSDNQPGVFIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGI 487
Query: 486 LNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKNSLESY 545
L+V+A D+STGK NKITITNDKGRLSKE++ERMV EAE+YKAEDE QRD+V++KNSLE++
Sbjct: 488 LSVTATDRSTGKANKITITNDKGRLSKEEVERMVHEAEQYKAEDEAQRDRVAAKNSLEAH 547
Query: 546 AFNMKATVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELEKVCNP 605
F++K ++++E L+ KI +ED++K+ DKC E++ WL+ NQ AEKEE+EHQ++ELE++C P
Sbjct: 548 VFHVKGSLQEESLRDKIPEEDRRKMQDKCREVLAWLEHNQLAEKEEYEHQKRELEQICRP 607
Query: 606 IITKLYQSAGGMPGGMPGGFPGGGAPPSGGASSGPTIEEVD 646
I ++LY GG G+PGG G G S+GP IEEVD
Sbjct: 608 IFSRLY---GG--PGVPGGSSCGTQARQGDPSTGPIIEEVD 643
>gi|24234686 heat shock 70kDa protein 8 isoform 2 [Homo sapiens]
Length = 493
Score = 912 bits (2356), Expect = 0.0
Identities = 467/473 (98%), Positives = 468/473 (98%), Gaps = 1/473 (0%)
Query: 1 MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA 60
MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA
Sbjct: 1 MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA 60
Query: 61 MNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVS 120
MNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVS
Sbjct: 61 MNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVS 120
Query: 121 SMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAA 180
SMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAA
Sbjct: 121 SMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAA 180
Query: 181 IAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH 240
IAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH
Sbjct: 181 IAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH 240
Query: 241 FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRA 300
FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRA
Sbjct: 241 FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRA 300
Query: 301 RFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELN 360
RFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELN
Sbjct: 301 RFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELN 360
Query: 361 KSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTI 420
KSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTI
Sbjct: 361 KSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTI 420
Query: 421 PTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPA-PRGVP 472
PTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTG+P P G P
Sbjct: 421 PTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGMPGGMPGGFP 473
Score = 71.2 bits (173), Expect = 3e-12
Identities = 31/31 (100%), Positives = 31/31 (100%)
Query: 616 GMPGGMPGGFPGGGAPPSGGASSGPTIEEVD 646
GMPGGMPGGFPGGGAPPSGGASSGPTIEEVD
Sbjct: 463 GMPGGMPGGFPGGGAPPSGGASSGPTIEEVD 493
>gi|16507237 heat shock 70kDa protein 5 [Homo sapiens]
Length = 654
Score = 803 bits (2075), Expect = 0.0
Identities = 410/620 (66%), Positives = 507/620 (81%), Gaps = 6/620 (0%)
Query: 4 GPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMN 62
G VGIDLGTTYSCVGVF++G+VEIIANDQGNR TPSYVAFT + ERLIGDAAKNQ+ N
Sbjct: 28 GTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSN 87
Query: 63 PTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKG-ETKSFYPEEVSS 121
P NTVFDAKRLIGR ++D VQ D+K PF VV +P +QV+ G +TK+F PEE+S+
Sbjct: 88 PENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISA 147
Query: 122 MVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAI 181
MVLTKMKE AEAYLGK VT+AVVTVPAYFND+QRQATKDAGTIAGLNV+RIINEPTAAAI
Sbjct: 148 MVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAI 207
Query: 182 AYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHF 241
AYGLDK+ G E+N+L+FDLGGGTFDVS+LTI++G+FEV +T GDTHLGGEDFD R++ HF
Sbjct: 208 AYGLDKREG-EKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHF 266
Query: 242 IAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRAR 301
I +K+K KD+ ++ RAV++LR E+AKR LSS QA IEI+S YEG DF ++TRA+
Sbjct: 267 IKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFYEGEDFSETLTRAK 326
Query: 302 FEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNK 361
FEELN DLFR T+ PV+K L D+ L KS I +IVLVGGSTRIPKIQ+L+++FFNGKE ++
Sbjct: 327 FEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSR 386
Query: 362 SINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIP 421
INPDEAVAYGAAVQA +LSGD ++ DL+LLDV PL+LGIET GGVMT LI RNT +P
Sbjct: 387 GINPDEAVAYGAAVQAGVLSGD--QDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVP 444
Query: 422 TKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDID 481
TK++Q F+T SDNQP V I+VYEGER +TKDN+LLG F+LTGIPPAPRGVPQIEVTF+ID
Sbjct: 445 TKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEID 504
Query: 482 ANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKNS 541
NGIL V+A DK TG +NKITITND+ RL+ E+IERMV +AEK+ ED+K ++++ ++N
Sbjct: 505 VNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNE 564
Query: 542 LESYAFNMKATVED-EKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELE 600
LESYA+++K + D EKL GK++ EDK+ + E I WL+ +Q A+ E+F+ ++KELE
Sbjct: 565 LESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEEKIEWLESHQDADIEDFKAKKKELE 624
Query: 601 KVCNPIITKLYQSAGGMPGG 620
++ PII+KLY SAG P G
Sbjct: 625 EIVQPIISKLYGSAGPPPTG 644
>gi|24234688 heat shock 70kDa protein 9 precursor [Homo sapiens]
Length = 679
Score = 576 bits (1484), Expect = e-164
Identities = 315/615 (51%), Positives = 418/615 (67%), Gaps = 18/615 (2%)
Query: 3 KGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAM 61
KG VGIDLGTT SCV V + + +++ N +G RTTPS VAFT D ERL+G AK Q
Sbjct: 52 KGAVVGIDLGTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVT 111
Query: 62 NPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSS 121
NP NT + KRLIGRR+DD VQ D+K+ PF +V A VE G K + P ++ +
Sbjct: 112 NPNNTFYATKRLIGRRYDDPEVQKDIKNVPFKIVR-ASNGDAWVEAHG--KLYSPSQIGA 168
Query: 122 MVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAI 181
VL KMKE AE YLG T NAV+TVPAYFNDSQRQATKDAG I+GLNVLR+INEPTAAA+
Sbjct: 169 FVLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAAL 228
Query: 182 AYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHF 241
AYGLDK ++ + ++DLGGGTFD+SIL I+ G+FEVKST GDT LGGEDFD ++ H
Sbjct: 229 AYGLDKS--EDKVIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQALLRHI 286
Query: 242 IAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGID----FYTSI 297
+ EFKR+ D++++ A++R+R A E+AK LSSS Q I + L +
Sbjct: 287 VKEFKRETGVDLTKDNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDSSGPKHLNMKL 346
Query: 298 TRARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGK 357
TRA+FE + DL R T+ P +KA++DA++ KS I +++LVGG TR+PK+Q+ +QD F G+
Sbjct: 347 TRAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDLF-GR 405
Query: 358 ELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRN 417
+K++NPDEAVA GAA+Q +L+GD V D+LLLDVTPLSLGIET GGV T LI RN
Sbjct: 406 APSKAVNPDEAVAIGAAIQGGVLAGD----VTDVLLLDVTPLSLGIETLGGVFTKLINRN 461
Query: 418 TTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVT 477
TTIPTK++Q F+T +D Q V I+V +GER M DN LLG+F L GIPPAPRGVPQIEVT
Sbjct: 462 TTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRGVPQIEVT 521
Query: 478 FDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVS 537
FDIDANGI++VSA DK TG+E +I I G LSK+DIE MV+ AEKY ED +++++V
Sbjct: 522 FDIDANGIVHVSAKDKGTGREQQIVI-QSSGGLSKDDIENMVKNAEKYAEEDRRKKERVE 580
Query: 538 SKNSLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQK 597
+ N E + + +E+ K Q + ++ K+ ++ +++ L + + E
Sbjct: 581 AVNMAEGIIHDTETKMEEFKDQ--LPADECNKLKEEISKMRELLARKDSETGENIRQAAS 638
Query: 598 ELEKVCNPIITKLYQ 612
L++ + Y+
Sbjct: 639 SLQQASLKLFEMAYK 653
>gi|82880658 heat shock 70kDa protein 14 isoform 1 [Homo sapiens]
Length = 509
Score = 310 bits (795), Expect = 2e-84
Identities = 175/505 (34%), Positives = 287/505 (56%), Gaps = 9/505 (1%)
Query: 6 AVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTN 65
A+G+ LG T +CV V++ G+ ++AND G+R TP+ VA+++ E ++G AAK N +N
Sbjct: 3 AIGVHLGCTSACVAVYKDGRAGVVANDAGDRVTPAVVAYSENEEIVGLAAKQSRIRNISN 62
Query: 66 TVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSSMVLT 125
TV K+++GR D Q + +V+ G+ + +++ ETK PE+V+ ++ +
Sbjct: 63 TVMKVKQILGRSSSDPQAQKYIAESKCLVIEKNGKLRYEIDTGEETKFVNPEDVARLIFS 122
Query: 126 KMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGL 185
KMKE A + LG + V+TVP F + Q+ A +A AG NVLR+I+EP+AA +AYG+
Sbjct: 123 KMKETAHSVLGSDANDVVITVPFDFGEKQKNALGEAARAAGFNVLRLIHEPSAALLAYGI 182
Query: 186 --DKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFIA 243
D G + N+L+F LGG + +S++ + GI+ V ST D ++GG F + + +
Sbjct: 183 GQDSPTG-KSNILVFKLGGTSLSLSVMEVNSGIYRVLSTNTDDNIGGAHFTETLAQYLAS 241
Query: 244 EFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRARFE 303
EF+R K D+ N RA+ +L + E AK +LS+ A+ +DSLYEG DF +++RARFE
Sbjct: 242 EFQRSFKHDVRGNARAMMKLTNSAEVAKHSLSTLGSANCFLDSLYEGQDFDCNVSRARFE 301
Query: 304 ELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSI 363
L + LF ++ + L I+ +VL GGS+RIPK+Q+L++D F EL SI
Sbjct: 302 LLCSPLFNKCIEAIRGLLDQNGFTADDINKVVLCGGSSRIPKLQQLIKDLFPAVELLNSI 361
Query: 364 NPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTP---LSLGIETAGGV-MTVLIKRNTT 419
PDE + GAA++A IL G ++ V+D L+++ + L G++ +G TVL T
Sbjct: 362 PPDEVIPIGAAIEAGILIGKENLLVEDSLMIECSARDILVKGVDESGASRFTVLFPSGTP 421
Query: 420 IPTKQTQTFTTYSDNQPGVLIQVYEGE-RAMTKDNNLLGKFELTGIPPAPRGVPQIEVTF 478
+P ++ T + V +++YE + + K+ + L + G+ I
Sbjct: 422 LPARRQHTLQA-PGSISSVCLELYESDGKNSAKEETKFAQVVLQDLDKKENGLRDILAVL 480
Query: 479 DIDANGILNVSAVDKSTGKENKITI 503
+ +G L+V+ D+ TGK I+I
Sbjct: 481 TMKRDGSLHVTCTDQETGKCEAISI 505
>gi|38327039 heat shock 70kDa protein 4 [Homo sapiens]
Length = 840
Score = 288 bits (738), Expect = 8e-78
Identities = 199/623 (31%), Positives = 322/623 (51%), Gaps = 36/623 (5%)
Query: 7 VGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNT 66
VGIDLG V V + G +E IAN+ +R TP+ ++F R IG AAK+QV N NT
Sbjct: 4 VGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNAKNT 63
Query: 67 VFDAKRLIGRRFDDAVVQSDMKHWPFMVVN-DAGRPKVQVEYKGETKSFYPEEVSSMVLT 125
V KR GR F D V+++ + + +V G ++V Y E ++F E+V++M+L+
Sbjct: 64 VQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAMLLS 123
Query: 126 KMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGL 185
K+KE AE+ L K V + VV+VP ++ D++R++ DA IAGLN LR++NE TA A+AYG+
Sbjct: 124 KLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALAYGI 183
Query: 186 DKK-----VGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH 240
K+ RNV+ D+G + VS+ G +V +TA DT LGG FD +VNH
Sbjct: 184 YKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVLVNH 243
Query: 241 FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLS-SSTQASIEIDSLYEGIDFYTSITR 299
F EF +K+K DI RA+ RL CE+ K+ +S +++ + I+ +D ++ R
Sbjct: 244 FCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGTMNR 303
Query: 300 ARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKEL 359
+F E+ DL P+ L KL K I+ + +VGG+TRIP +++ + FF GKEL
Sbjct: 304 GKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFF-GKEL 362
Query: 360 NKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIE-----TAGGVMTVLI 414
+ ++N DEAV G A+Q AILS + V++ + DV P + + G +
Sbjct: 363 STTLNADEAVTRGCALQCAILS--PAFKVREFSITDVVPYPISLRWNSPAEEGSSDCEVF 420
Query: 415 KRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRG-VPQ 473
+N P + TF +P L Y + + + + +F + + P G +
Sbjct: 421 SKNHAAPFSKVLTFYR---KEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGSSSK 477
Query: 474 IEVTFDIDANGILNVSA---VDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDE 530
++V ++ +GI +VS+ V+ +EN+ + D+ +KE+ + V + E + E
Sbjct: 478 VKVKVRVNVHGIFSVSSASLVEVHKSEENEEPMETDQN--AKEEEKMQVDQEEPHV---E 532
Query: 531 KQRDKVSSKNSLESYAFNMKATVEDEKLQGKINDEDKQKI------LDKCNEIINWLDK- 583
+Q+ + ++N ES +K + K K+ L N+++ +D+
Sbjct: 533 EQQQQTPAENKAESEEMETSQAGSKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDRE 592
Query: 584 --NQTAEKEEFEHQQKELEKVCN 604
N E E Q +LEK N
Sbjct: 593 MLNLYIENEGKMIMQDKLEKERN 615
Score = 39.3 bits (90), Expect = 0.011
Identities = 22/110 (20%), Positives = 56/110 (50%), Gaps = 10/110 (9%)
Query: 509 RLSKEDIERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKATVEDEKLQGK----IND 564
++ +E + ++ K +D+ ++++ +KN++E Y + M+ +KL G+ +++
Sbjct: 588 QIDREMLNLYIENEGKMIMQDKLEKERNDAKNAVEEYVYEMR-----DKLSGEYEKFVSE 642
Query: 565 EDKQKILDKCNEIINWL-DKNQTAEKEEFEHQQKELEKVCNPIITKLYQS 613
+D+ K + NWL + + K+ + + EL+ + PI + +S
Sbjct: 643 DDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKNLGQPIKIRFQES 692
Score = 31.6 bits (70), Expect = 2.4
Identities = 25/118 (21%), Positives = 50/118 (42%), Gaps = 12/118 (10%)
Query: 493 KSTGKENKITITNDKGRLSK-EDIERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKA 551
K+ G+ KI + R E++ + +Q+ K + + + D+ ++ +
Sbjct: 679 KNLGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKST 738
Query: 552 TVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELEKVCNPIITK 609
E + K+N ++KQ L + + +E E + KEL C+PII+K
Sbjct: 739 NEAMEWMNNKLNLQNKQS-----------LTMDPVVKSKEIEAKIKELTSTCSPIISK 785
>gi|48928056 heat shock protein 70kDa family member 13 precursor
[Homo sapiens]
Length = 471
Score = 276 bits (707), Expect = 3e-74
Identities = 167/421 (39%), Positives = 246/421 (58%), Gaps = 50/421 (11%)
Query: 7 VGIDLGTTYSCVGVF--QHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPT 64
+GIDLGTTY VGVF GKV++I ++ G+ + PS V+FTD + +G + NP
Sbjct: 34 IGIDLGTTYCSVGVFFPGTGKVKVIPDENGHISIPSMVSFTDNDVYVGYESVELADSNPQ 93
Query: 65 NTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSSMVL 124
NT++DAKR IG+ F +++++ +PF V+N G + V ET + PE V S +L
Sbjct: 94 NTIYDAKRFIGKIFTAEELEAEIGRYPFKVLNKNGMVEFSVT-SNETITVSPEYVGSRLL 152
Query: 125 TKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYG 184
K+KE+AEAYLG V NAV++VPA F+ QR +T +A +AGL +LR+INEPTAAA+AYG
Sbjct: 153 LKLKEMAEAYLGMPVANAVISVPAEFDLKQRNSTIEAANLAGLKILRVINEPTAAAMAYG 212
Query: 185 LDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFIAE 244
L K +VL+ DLGGGT DVS+L + G+F ++ +G+ LGG+DF+ R++ + +
Sbjct: 213 LHK--ADVFHVLVIDLGGGTLDVSLLNKQGGMFLTRAMSGNNKLGGQDFNQRLLQYLYKQ 270
Query: 245 FKRKHKKDISENKRAVRRLRTACERAK--RTLSSSTQASIEI------------------ 284
+ + + K + RLR A E K TL S Q S+ +
Sbjct: 271 IYQTY-GFVPSRKEEIHRLRQAVEMVKLNLTLHQSAQLSVLLTVEEQDRKEPHSSDTELP 329
Query: 285 -DSLYEGID----------------------FYTSITRARFEELNADLFRGTLDPVEKAL 321
D L D F T I+R F+ LN DLF+ L P+++ L
Sbjct: 330 KDKLSSADDHRVNSGFGRGLSDKKSGESQVLFETEISRKLFDTLNEDLFQKILVPIQQVL 389
Query: 322 RDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILS 381
++ L+K++I ++VLVGGSTRIP+I++++Q+FF GK+ N S++PD AV G A+QA I
Sbjct: 390 KEGHLEKTEIDEVVLVGGSTRIPRIRQVIQEFF-GKDPNTSVDPDLAVVTGVAIQAGIDG 448
Query: 382 G 382
G
Sbjct: 449 G 449
>gi|42544159 heat shock 105kD [Homo sapiens]
Length = 858
Score = 271 bits (694), Expect = 1e-72
Identities = 191/610 (31%), Positives = 314/610 (51%), Gaps = 34/610 (5%)
Query: 7 VGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNT 66
VG+D+G+ + V + G +E IAN+ +R TPS ++F R IG AAKNQ + NT
Sbjct: 4 VGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITHANNT 63
Query: 67 VFDAKRLIGRRFDDAVVQSDMKHWPF-MVVNDAGRPKVQVEYKGETKSFYPEEVSSMVLT 125
V + KR GR F+D +Q + ++ + +V G ++V Y GE F E++++M+LT
Sbjct: 64 VSNFKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAMLLT 123
Query: 126 KMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGL 185
K+KE AE L K VT+ V++VP++F D++R++ DA I GLN LR++N+ TA A+ YG+
Sbjct: 124 KLKETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALNYGI 183
Query: 186 DKK----VGAERNVLIF-DLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH 240
K+ + + +++F D+G F VS G +V TA D LGG++FD ++V H
Sbjct: 184 YKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKLVEH 243
Query: 241 FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSS-STQASIEIDSLYEGIDFYTSITR 299
F AEFK K+K D RA+ RL CE+ K+ +SS ST + I+ D + R
Sbjct: 244 FCAEFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGKMNR 303
Query: 300 ARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKEL 359
++FEEL A+L + P+ L L + + +VGG+TRIP +++ + FF GK++
Sbjct: 304 SQFEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFF-GKDI 362
Query: 360 NKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGI------ETAGGVMTVL 413
+ ++N DEAVA G A+Q AILS + V++ + D P + + E GV V
Sbjct: 363 STTLNADEAVARGCALQCAILS--PAFKVREFSVTDAVPFPISLIWNHDSEDTEGVHEV- 419
Query: 414 IKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRG-VP 472
RN P + TF P L Y + + +G+F + + G
Sbjct: 420 FSRNHAAPFSKVLTFLR---RGPFELEAFYSDPQGVPYPEAKIGRFVVQNVSAQKDGEKS 476
Query: 473 QIEVTFDIDANGILNVSA---VDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAED 529
+++V ++ +GI +S V+K +EN+++ S+ D+E + Q + D
Sbjct: 477 RVKVKVRVNTHGIFTISTASMVEKVPTEENEMS--------SEADMECLNQRPPENPDTD 528
Query: 530 EKQRDKVSSKNSLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEK 589
+ + S + + + T + ++E+K DK NE +D+ A+K
Sbjct: 529 KNVQQDNSEAGTQPQVQTDAQQTSQSPPSPELTSEENKIPDADKANE--KKVDQPPEAKK 586
Query: 590 EEFEHQQKEL 599
+ + EL
Sbjct: 587 PKIKVVNVEL 596
Score = 37.7 bits (86), Expect = 0.033
Identities = 35/163 (21%), Positives = 73/163 (44%), Gaps = 22/163 (13%)
Query: 465 PPAPRGVPQIEVTFDIDANGILNVSAVDKST-GKENKITITNDK--------GRLSKEDI 515
PP+P + D D N VD+ K+ KI + N + +L K+ +
Sbjct: 555 PPSPELTSEENKIPDADK---ANEKKVDQPPEAKKPKIKVVNVELPIEANLVWQLGKDLL 611
Query: 516 ERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKATVEDEKLQGK----INDEDKQKIL 571
++ K +D+ ++++ +KN++E Y + + +KL G I ++D Q L
Sbjct: 612 NMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFR-----DKLCGPYEKFICEQDHQNFL 666
Query: 572 DKCNEIINWL-DKNQTAEKEEFEHQQKELEKVCNPIITKLYQS 613
E +WL ++ + K+ + + +EL K+ P+ + ++
Sbjct: 667 RLLTETEDWLYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEA 709
Score = 33.5 bits (75), Expect = 0.62
Identities = 20/100 (20%), Positives = 45/100 (45%), Gaps = 14/100 (14%)
Query: 524 KYKAEDEKQRDKVSSK--NSLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIINW- 580
K + ++ ++R K+ + L+ YA ++ I++ + +K+ NE++ W
Sbjct: 703 KVRFQEAEERPKMFEELGQRLQHYAKIAADFRNKDEKYNHIDESEMKKVEKSVNEVMEWM 762
Query: 581 -----------LDKNQTAEKEEFEHQQKELEKVCNPIITK 609
LD++ +E + + KEL C P++T+
Sbjct: 763 NNVMNAQAKKSLDQDPVVRAQEIKTKIKELNNTCEPVVTQ 802
>gi|31541941 heat shock 70kDa protein 4-like [Homo sapiens]
Length = 839
Score = 268 bits (686), Expect = 9e-72
Identities = 172/564 (30%), Positives = 293/564 (51%), Gaps = 32/564 (5%)
Query: 7 VGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNT 66
VGIDLG + V + G +E IAN+ +R TP+ ++ R IG+AAK+Q+ N NT
Sbjct: 4 VGIDLGFLNCYIAVARSGGIETIANEYSDRCTPACISLGSRTRAIGNAAKSQIVTNVRNT 63
Query: 67 VFDAKRLIGRRFDDAVVQSDMKHWPFMVVN-DAGRPKVQVEYKGETKSFYPEEVSSMVLT 125
+ K+L GR FDD +VQ++ P+ + G V+V Y E + F E+V+ M+L
Sbjct: 64 IHGFKKLHGRSFDDPIVQTERIRLPYELQKMPNGSAGVKVRYLEEERPFAIEQVTGMLLA 123
Query: 126 KMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGL 185
K+KE +E L K V + V+++P++F D++R++ A +AGLN LR++NE TA A+AYG+
Sbjct: 124 KLKETSENALKKPVADCVISIPSFFTDAERRSVMAAAQVAGLNCLRLMNETTAVALAYGI 183
Query: 186 DKK-----VGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH 240
K+ RNV+ D+G + V + G +V +T D +LGG +FD +V++
Sbjct: 184 YKQDLPPLDEKPRNVVFIDMGHSAYQVLVCAFNKGKLKVLATTFDPYLGGRNFDEALVDY 243
Query: 241 FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLS-SSTQASIEIDSLYEGIDFYTSITR 299
F EFK K+K ++ EN RA+ RL CE+ K+ +S +++ + I+ +D + + R
Sbjct: 244 FCDEFKTKYKINVKENSRALLRLYQECEKLKKLMSANASDLPLNIECFMNDLDVSSKMNR 303
Query: 300 ARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKEL 359
A+FE+L A L P++ + A L + I I +VGG+TRIP +++ + FF K++
Sbjct: 304 AQFEQLCASLLARVEPPLKAVMEQANLQREDISSIEIVGGATRIPAVKEQITKFFL-KDI 362
Query: 360 NKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSL------GIETAGGVMTVL 413
+ ++N DEAVA G A+Q AILS + V++ + D+ P S+ E G V
Sbjct: 363 STTLNADEAVARGCALQCAILS--PAFKVREFSITDLVPYSITLRWKTSFEDGSGECEVF 420
Query: 414 IKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRG-VP 472
K + +K T+ +P L Y + + +G F + + P G
Sbjct: 421 CKNHPAPFSK----VITFHKKEPFELEAFYTNLHEVPYPDARIGSFTIQNVFPQSDGDSS 476
Query: 473 QIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQ 532
+++V ++ +GI +V++ +K L + + ++ +K E++
Sbjct: 477 KVKVKVRVNIHGIFSVASAS-----------VIEKQNLEGDHSDAPMETETSFKNENKDN 525
Query: 533 RDKVSSKNSLESYAFNMKATVEDE 556
DK+ + + T E+E
Sbjct: 526 MDKMQVDQEEGHQKCHAEHTPEEE 549
Score = 35.8 bits (81), Expect = 0.13
Identities = 31/147 (21%), Positives = 65/147 (44%), Gaps = 20/147 (13%)
Query: 479 DIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDI---------------ERMVQEAE 523
+ID G SAV + K++++ T KG++ D+ ++
Sbjct: 549 EIDHTGAKTKSAV---SDKQDRLNQTLKKGKVKSIDLPIQSSLCRQLGQDLLNSYIENEG 605
Query: 524 KYKAEDEKQRDKVSSKNSLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIINWL-D 582
K +D+ ++++ +KN++E Y ++ + + + I ED K+ + NWL +
Sbjct: 606 KMIMQDKLEKERNDAKNAVEEYVYDFRDRL-GTVYEKFITPEDLSKLSAVLEDTENWLYE 664
Query: 583 KNQTAEKEEFEHQQKELEKVCNPIITK 609
+ K+ + + +EL+K PI K
Sbjct: 665 DGEDQPKQVYVDKLQELKKYGQPIQMK 691
>gi|195976805 hypoxia up-regulated 1 precursor [Homo sapiens]
Length = 999
Score = 227 bits (578), Expect = 3e-59
Identities = 176/598 (29%), Positives = 290/598 (48%), Gaps = 65/598 (10%)
Query: 7 VGIDLGTTYSCVGVFQHG-KVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTN 65
+ +DLG+ V + + G +EI+ N + R TP V + ER GD+A + NP
Sbjct: 36 MSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVIVTLKENERFFGDSAASMAIKNPKA 95
Query: 66 TVFDAKRLIGRRFDDAVVQSDMKHWP-FMVVNDAGRPKVQVEYKGETKSFYPEEVSSMVL 124
T+ + L+G++ D+ V +P + D R V + + + F PEEV MVL
Sbjct: 96 TLRYFQHLLGKQADNPHVALYQARFPEHELTFDPQRQTVHFQISSQLQ-FSPEEVLGMVL 154
Query: 125 TKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYG 184
+ +AE + + + +AV+TVP +FN ++R+A A +AGL VL++IN+ TA A++YG
Sbjct: 155 NYSRSLAEDFAEQPIKDAVITVPVFFNQAERRAVLQAARMAGLKVLQLINDNTATALSYG 214
Query: 185 LDKKVGAE---RNVLIFDLGGGTFDVSILTI------EDGI---FEVKSTAGDTHLGGED 232
+ ++ +N++ +D+G G+ +I+T E G+ +++ D LGG +
Sbjct: 215 VFRRKDINTTAQNIMFYDMGSGSTVCTIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLE 274
Query: 233 FDNRMVNHFIAEFKRKHK----KDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLY 288
+ R+ F + K KD+ EN RA+ +L R K LS++ +I+ L
Sbjct: 275 MELRLRERLAGLFNEQRKGQRAKDVRENPRAMAKLLREANRLKTVLSANADHMAQIEGLM 334
Query: 289 EGIDFYTSITRARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQK 348
+ +DF +TR FEEL ADLF PV++AL+ A++ +I ++LVGG+TR+P++Q+
Sbjct: 335 DDVDFKAKVTRVEFEELCADLFERVPGPVQQALQSAEMSLDEIEQVILVGGATRVPRVQE 394
Query: 349 LLQDFFNGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLD--VTPLSL----- 401
+L +EL K+IN DEA A GA QAA LS K+ V+ ++ D V P+ +
Sbjct: 395 VLLKAVGKEELGKNINADEAAAMGAVYQAAALS--KAFKVKPFVVRDAVVYPILVEFTRE 452
Query: 402 -----GIETAGGVMTVLIKRNTTIPTKQTQTFTTYSD------NQPGVLIQVYEGERAMT 450
GI + VL R P ++ TF YS N + E R
Sbjct: 453 VEEEPGIHSLKHNKRVLFSRMGPYPQRKVITFNRYSHDFNFHINYGDLGFLGPEDLRVFG 512
Query: 451 KDNNLLGKFELTGIPPAPRGVPQ-----IEVTFDIDANGILNVSAVDK------STGKEN 499
N L +L G+ + + P I+ F++D +G+L++ V+ E
Sbjct: 513 SQN--LTTVKLKGVGDSFKKYPDYESKGIKAHFNLDESGVLSLDRVESVFETLVEDSAEE 570
Query: 500 KITITNDKGRLS-----------KEDIERMVQEAEKYKAEDEKQR--DKVSSKNSLES 544
+ T+T +S KE+ VQE E+ AE K ++V K E+
Sbjct: 571 ESTLTKLGNTISSLFGGGTTPDAKENGTDTVQEEEESPAEGSKDEPGEQVELKEEAEA 628
Score = 42.0 bits (97), Expect = 0.002
Identities = 51/273 (18%), Positives = 106/273 (38%), Gaps = 45/273 (16%)
Query: 376 QAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTY---- 431
++ +LS D+ E+V + L+ D + G ++ L TT K+ T T
Sbjct: 547 ESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDTVQEEEE 606
Query: 432 -----SDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRG--VPQIEVTFDID--- 481
S ++PG +++ E A +D + PP P+G P+ E + +
Sbjct: 607 SPAEGSKDEPGEQVELKEEAEAPVEDGS-------QPPPPEPKGDATPEGEKATEKENGD 659
Query: 482 --------------ANGILNVSAVDKSTGKENKITITNDKG---------RLSKEDIERM 518
G+ +K K + + G L ++ + +
Sbjct: 660 KSEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQS 719
Query: 519 VQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEII 578
VQ+ + D +++++ + NSLE++ F + + + Q +E +++I K +
Sbjct: 720 VQKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAS 779
Query: 579 NWL-DKNQTAEKEEFEHQQKELEKVCNPIITKL 610
WL D+ A + + EL K+C + ++
Sbjct: 780 TWLEDEGVGATTVMLKEKLAELRKLCQGLFFRV 812
>gi|5453832 hypoxia up-regulated 1 precursor [Homo sapiens]
Length = 999
Score = 227 bits (578), Expect = 3e-59
Identities = 176/598 (29%), Positives = 290/598 (48%), Gaps = 65/598 (10%)
Query: 7 VGIDLGTTYSCVGVFQHG-KVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTN 65
+ +DLG+ V + + G +EI+ N + R TP V + ER GD+A + NP
Sbjct: 36 MSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVIVTLKENERFFGDSAASMAIKNPKA 95
Query: 66 TVFDAKRLIGRRFDDAVVQSDMKHWP-FMVVNDAGRPKVQVEYKGETKSFYPEEVSSMVL 124
T+ + L+G++ D+ V +P + D R V + + + F PEEV MVL
Sbjct: 96 TLRYFQHLLGKQADNPHVALYQARFPEHELTFDPQRQTVHFQISSQLQ-FSPEEVLGMVL 154
Query: 125 TKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYG 184
+ +AE + + + +AV+TVP +FN ++R+A A +AGL VL++IN+ TA A++YG
Sbjct: 155 NYSRSLAEDFAEQPIKDAVITVPVFFNQAERRAVLQAARMAGLKVLQLINDNTATALSYG 214
Query: 185 LDKKVGAE---RNVLIFDLGGGTFDVSILTI------EDGI---FEVKSTAGDTHLGGED 232
+ ++ +N++ +D+G G+ +I+T E G+ +++ D LGG +
Sbjct: 215 VFRRKDINTTAQNIMFYDMGSGSTVCTIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLE 274
Query: 233 FDNRMVNHFIAEFKRKHK----KDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLY 288
+ R+ F + K KD+ EN RA+ +L R K LS++ +I+ L
Sbjct: 275 MELRLRERLAGLFNEQRKGQRAKDVRENPRAMAKLLREANRLKTVLSANADHMAQIEGLM 334
Query: 289 EGIDFYTSITRARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQK 348
+ +DF +TR FEEL ADLF PV++AL+ A++ +I ++LVGG+TR+P++Q+
Sbjct: 335 DDVDFKAKVTRVEFEELCADLFERVPGPVQQALQSAEMSLDEIEQVILVGGATRVPRVQE 394
Query: 349 LLQDFFNGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLD--VTPLSL----- 401
+L +EL K+IN DEA A GA QAA LS K+ V+ ++ D V P+ +
Sbjct: 395 VLLKAVGKEELGKNINADEAAAMGAVYQAAALS--KAFKVKPFVVRDAVVYPILVEFTRE 452
Query: 402 -----GIETAGGVMTVLIKRNTTIPTKQTQTFTTYSD------NQPGVLIQVYEGERAMT 450
GI + VL R P ++ TF YS N + E R
Sbjct: 453 VEEEPGIHSLKHNKRVLFSRMGPYPQRKVITFNRYSHDFNFHINYGDLGFLGPEDLRVFG 512
Query: 451 KDNNLLGKFELTGIPPAPRGVPQ-----IEVTFDIDANGILNVSAVDK------STGKEN 499
N L +L G+ + + P I+ F++D +G+L++ V+ E
Sbjct: 513 SQN--LTTVKLKGVGDSFKKYPDYESKGIKAHFNLDESGVLSLDRVESVFETLVEDSAEE 570
Query: 500 KITITNDKGRLS-----------KEDIERMVQEAEKYKAEDEKQR--DKVSSKNSLES 544
+ T+T +S KE+ VQE E+ AE K ++V K E+
Sbjct: 571 ESTLTKLGNTISSLFGGGTTPDAKENGTDTVQEEEESPAEGSKDEPGEQVELKEEAEA 628
Score = 42.0 bits (97), Expect = 0.002
Identities = 51/273 (18%), Positives = 106/273 (38%), Gaps = 45/273 (16%)
Query: 376 QAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTY---- 431
++ +LS D+ E+V + L+ D + G ++ L TT K+ T T
Sbjct: 547 ESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDTVQEEEE 606
Query: 432 -----SDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRG--VPQIEVTFDID--- 481
S ++PG +++ E A +D + PP P+G P+ E + +
Sbjct: 607 SPAEGSKDEPGEQVELKEEAEAPVEDGS-------QPPPPEPKGDATPEGEKATEKENGD 659
Query: 482 --------------ANGILNVSAVDKSTGKENKITITNDKG---------RLSKEDIERM 518
G+ +K K + + G L ++ + +
Sbjct: 660 KSEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQS 719
Query: 519 VQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEII 578
VQ+ + D +++++ + NSLE++ F + + + Q +E +++I K +
Sbjct: 720 VQKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAS 779
Query: 579 NWL-DKNQTAEKEEFEHQQKELEKVCNPIITKL 610
WL D+ A + + EL K+C + ++
Sbjct: 780 TWLEDEGVGATTVMLKEKLAELRKLCQGLFFRV 812
>gi|38348298 ankyrin repeat domain 45 [Homo sapiens]
Length = 266
Score = 47.0 bits (110), Expect = 5e-05
Identities = 31/97 (31%), Positives = 47/97 (48%), Gaps = 2/97 (2%)
Query: 516 ERMVQEAEKY-KAEDEKQRDKVSSKNSLESYAFNMKATVED-EKLQGKINDEDKQKILDK 573
ER A +Y + E + D ++ +L+ Y + V D EK GK+ EDK IL
Sbjct: 144 ERARDVAARYSQTECVEFLDWADARLTLKKYIAKVSLAVTDTEKGSGKLLKEDKNTILSA 203
Query: 574 CNEIINWLDKNQTAEKEEFEHQQKELEKVCNPIITKL 610
C WL+ + A E Q+++LE + PI TK+
Sbjct: 204 CRAKNEWLETHTEASINELFEQRQQLEDIVTPIFTKM 240
>gi|9910266 kinesin family member 15 [Homo sapiens]
Length = 1388
Score = 43.5 bits (101), Expect = 6e-04
Identities = 59/292 (20%), Positives = 124/292 (42%), Gaps = 28/292 (9%)
Query: 302 FEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNK 361
FE ++ +L T+ AL+ AKLD+ + ++ L ++ +Q+ F+ + ++
Sbjct: 712 FEAISEEL--RTVQEQMSALQ-AKLDEEEHKNLKLQQHVDKLEHHSTQMQELFSSERIDW 768
Query: 362 SINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIP 421
+ +E ++ ++ + +++ D L +V L + + +A ++ + ++
Sbjct: 769 TKQQEELLSQLNVLEKQL---QETQTKNDFLKSEVHDLRVVLHSADKELSSVKLEYSSFK 825
Query: 422 TKQTQTFTTYSDNQPGVLIQV----YEGERAMTKD-------NNL--LGKFELTGIPPAP 468
T Q + F S+ V +Q+ E E+ + +NL + KFE+ +
Sbjct: 826 TNQEKEFNKLSERHMHVQLQLDNLRLENEKLLESKACLQDSYDNLQEIMKFEIDQLSRNL 885
Query: 469 RGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKE---DIERMVQEAEKY 525
+ + T D N ++ + +K + + DK SKE +E + QE +K
Sbjct: 886 QNFKKENETLKSDLNNLMELLEAEKERNNKLSLQFEEDKENSSKEILKVLEAVRQEKQKE 945
Query: 526 KAEDEKQRDKVSSKNSLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEI 577
A+ E+Q KV ++ AT + K D DK+ + D N+I
Sbjct: 946 TAKCEQQMAKVQKLEE------SLLATEKVISSLEKSRDSDKKVVADLMNQI 991
>gi|32967605 bromodomain adjacent to zinc finger domain, 1A isoform
b [Homo sapiens]
Length = 1524
Score = 40.0 bits (92), Expect = 0.007
Identities = 29/96 (30%), Positives = 51/96 (53%), Gaps = 8/96 (8%)
Query: 510 LSKEDIERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKATVEDEKLQG----KINDE 565
+S+ED Q Y+++ K+RDK+ + ++S AF KA ++ EK K E
Sbjct: 285 ISQEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFE-KAKLKREKADALEAKKKEKE 343
Query: 566 DKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELEK 601
DK+K ++ +I+ ++ + +KEE E + E EK
Sbjct: 344 DKEKKREELKKIV---EEERLKKKEEKERLKVEREK 376
Score = 30.4 bits (67), Expect = 5.3
Identities = 24/120 (20%), Positives = 63/120 (52%), Gaps = 4/120 (3%)
Query: 493 KSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKAT 552
K+T + +K+ + L+ E + ++A+ +A+ +++ DK + L+ +
Sbjct: 303 KATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKEDKEKKREELKKIVEEERLK 362
Query: 553 VEDEKLQGKI-NDEDKQKILDKCNEIINWLDKNQTAEKEEFE-HQQKELEKVCNPIITKL 610
++EK + K+ +++++K+ ++ + + +L K + +E+ E KEL + P+ T+L
Sbjct: 363 KKEEKERLKVEREKEREKLREEKRKYVEYL-KQWSKPREDMECDDLKELPEP-TPVKTRL 420
>gi|32967603 bromodomain adjacent to zinc finger domain, 1A isoform
a [Homo sapiens]
Length = 1556
Score = 40.0 bits (92), Expect = 0.007
Identities = 29/96 (30%), Positives = 51/96 (53%), Gaps = 8/96 (8%)
Query: 510 LSKEDIERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKATVEDEKLQG----KINDE 565
+S+ED Q Y+++ K+RDK+ + ++S AF KA ++ EK K E
Sbjct: 285 ISQEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFE-KAKLKREKADALEAKKKEKE 343
Query: 566 DKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELEK 601
DK+K ++ +I+ ++ + +KEE E + E EK
Sbjct: 344 DKEKKREELKKIV---EEERLKKKEEKERLKVEREK 376
Score = 30.4 bits (67), Expect = 5.3
Identities = 24/120 (20%), Positives = 63/120 (52%), Gaps = 4/120 (3%)
Query: 493 KSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKAT 552
K+T + +K+ + L+ E + ++A+ +A+ +++ DK + L+ +
Sbjct: 303 KATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKEDKEKKREELKKIVEEERLK 362
Query: 553 VEDEKLQGKI-NDEDKQKILDKCNEIINWLDKNQTAEKEEFE-HQQKELEKVCNPIITKL 610
++EK + K+ +++++K+ ++ + + +L K + +E+ E KEL + P+ T+L
Sbjct: 363 KKEEKERLKVEREKEREKLREEKRKYVEYL-KQWSKPREDMECDDLKELPEP-TPVKTRL 420
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 38.9 bits (89), Expect = 0.015
Identities = 35/139 (25%), Positives = 70/139 (50%), Gaps = 8/139 (5%)
Query: 469 RGVPQIEVTFDIDANGILNVSAVDKSTGKEN-----KITITNDKGRLSKEDIERMVQEAE 523
RG+ ++ V + D L+++ K +EN K+ + ++S+E+ E ++ +AE
Sbjct: 2119 RGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAE 2178
Query: 524 KYKAEDEKQRDKVSS-KNSLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIINWLD 582
KAE E + ++ SL+ + ++ T+ EK ++KQ L + +++++
Sbjct: 2179 NSKAEVETLKTQIEEMARSLKVFELDL-VTLRSEKENLTKQIQEKQGQLSELDKLLSSF- 2236
Query: 583 KNQTAEKEEFEHQQKELEK 601
K+ EKE+ E Q KE K
Sbjct: 2237 KSLLEEKEQAEIQIKEESK 2255
Score = 31.6 bits (70), Expect = 2.4
Identities = 21/86 (24%), Positives = 44/86 (51%), Gaps = 9/86 (10%)
Query: 513 EDIERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKATVEDEKLQGKINDEDKQKILD 572
+ I+ + + +K K E ++++ ++ +SLE+ K VE+EK +G + Q++++
Sbjct: 18 QKIQELEGQLDKLKKEKQQRQFQL---DSLEAALQKQKQKVENEKTEGTNLKRENQRLME 74
Query: 573 KCNEIINWLDKNQTAEKEEFEHQQKE 598
C + +T +K E Q KE
Sbjct: 75 ICESL------EKTKQKISHELQVKE 94
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 38.5 bits (88), Expect = 0.019
Identities = 27/100 (27%), Positives = 49/100 (49%), Gaps = 10/100 (10%)
Query: 503 ITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKATVEDEKLQGKI 562
+T +K L E++ E E Y +E + + K LE M+A +E+E+ +G+
Sbjct: 885 LTEEKNLLQ----EQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQ 940
Query: 563 NDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELEKV 602
+++K+ + LD + E+EE Q+ +LEKV
Sbjct: 941 LQAERKKMAQQM------LDLEEQLEEEEAARQKLQLEKV 974
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 38.5 bits (88), Expect = 0.019
Identities = 27/100 (27%), Positives = 49/100 (49%), Gaps = 10/100 (10%)
Query: 503 ITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKATVEDEKLQGKI 562
+T +K L E++ E E Y +E + + K LE M+A +E+E+ +G+
Sbjct: 892 LTEEKNLLQ----EQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQ 947
Query: 563 NDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELEKV 602
+++K+ + LD + E+EE Q+ +LEKV
Sbjct: 948 LQAERKKMAQQM------LDLEEQLEEEEAARQKLQLEKV 981
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 38.5 bits (88), Expect = 0.019
Identities = 27/100 (27%), Positives = 49/100 (49%), Gaps = 10/100 (10%)
Query: 503 ITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKATVEDEKLQGKI 562
+T +K L E++ E E Y +E + + K LE M+A +E+E+ +G+
Sbjct: 892 LTEEKNLLQ----EQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQ 947
Query: 563 NDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELEKV 602
+++K+ + LD + E+EE Q+ +LEKV
Sbjct: 948 LQAERKKMAQQM------LDLEEQLEEEEAARQKLQLEKV 981
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 38.5 bits (88), Expect = 0.019
Identities = 27/100 (27%), Positives = 49/100 (49%), Gaps = 10/100 (10%)
Query: 503 ITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKATVEDEKLQGKI 562
+T +K L E++ E E Y +E + + K LE M+A +E+E+ +G+
Sbjct: 885 LTEEKNLLQ----EQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQ 940
Query: 563 NDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELEKV 602
+++K+ + LD + E+EE Q+ +LEKV
Sbjct: 941 LQAERKKMAQQM------LDLEEQLEEEEAARQKLQLEKV 974
>gi|19923193 heat shock 70kD protein binding protein [Homo sapiens]
Length = 369
Score = 38.5 bits (88), Expect = 0.019
Identities = 22/59 (37%), Positives = 30/59 (50%), Gaps = 2/59 (3%)
Query: 582 DKNQTAEKEEFEHQQKELEKVCNPIITKLYQS-AGGMPGGMPGGFPGGGAPPSGGASSG 639
++ + +K EH++ + E+ Y S GG PGGMPG FP GG P GG G
Sbjct: 249 ERIERVKKAREEHERAQREEEARRQSGAQYGSFPGGFPGGMPGNFP-GGMPGMGGGMPG 306
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 38.1 bits (87), Expect = 0.025
Identities = 30/125 (24%), Positives = 59/125 (47%), Gaps = 20/125 (16%)
Query: 497 KENKITITNDKGRLSKEDIERMVQE------AEKYKAEDEK--------------QRDKV 536
++++I+ ++ R +E+ ER ++E AEK K DEK +R++
Sbjct: 451 QQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIRERERE 510
Query: 537 SSKNSLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQ 596
+ + + E E+ + + ++K+K L+K E ++K + EKE+ +Q
Sbjct: 511 KEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQ 570
Query: 597 KELEK 601
KE EK
Sbjct: 571 KEKEK 575
Score = 33.1 bits (74), Expect = 0.82
Identities = 28/101 (27%), Positives = 52/101 (51%), Gaps = 9/101 (8%)
Query: 506 DKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKATVEDEKLQGKINDE 565
+K R ++++E+ QE E+ K E EK R++ K ++ E ++ K +
Sbjct: 510 EKEREREKELEKE-QEQEREK-EREKDRERQQEKEK------ELEKEQEKQREMEKERKQ 561
Query: 566 DKQKILDKCNEIINWLDKNQTAEKE-EFEHQQKELEKVCNP 605
+K+K L++ E L K + EKE E E ++++LE+ P
Sbjct: 562 EKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEP 602
>gi|34878777 ring finger protein 20 [Homo sapiens]
Length = 975
Score = 37.4 bits (85), Expect = 0.043
Identities = 38/135 (28%), Positives = 59/135 (43%), Gaps = 30/135 (22%)
Query: 489 SAVDKSTGKENKITITNDKGRLSKEDIERMV-------QEAEK--------YKAEDEKQR 533
SA DK GK +D GR + +I + + QE++K Y++ ++QR
Sbjct: 606 SAKDKEKGK-------HDDGRKKEAEIIKQLKIELKKAQESQKEMKLLLDMYRSAPKEQR 658
Query: 534 DKVS-------SKNSLESYAFNMKATVEDEKLQGK-INDEDKQKILDKCNEIINWLDKNQ 585
DKV SK LE +K + EK + K + DED + + E I +L K
Sbjct: 659 DKVQLMAAEKKSKAELEDLRQRLKDLEDKEKKENKKMADEDALRKIRAVEEQIEYLQKKL 718
Query: 586 TAEKEEFEHQQKELE 600
K+E E E++
Sbjct: 719 AMAKQEEEALLSEMD 733
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 36.6 bits (83), Expect = 0.074
Identities = 28/136 (20%), Positives = 63/136 (46%), Gaps = 3/136 (2%)
Query: 488 VSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKNSLESYAF 547
V ++ S +E K+ + ++ + E ++ QE+ A+D++Q ++ K E
Sbjct: 1080 VEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQL 1139
Query: 548 NMKATVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELEKVCNPII 607
+++ VEDE+L G + +++ + E+ L+ + A + E Q+ E + +
Sbjct: 1140 SLR--VEDEQLLGAQMQKKIKELQARAEELEEELEAERAA-RARVEKQRAEAARELEELS 1196
Query: 608 TKLYQSAGGMPGGMPG 623
+L ++ G G G
Sbjct: 1197 ERLEEAGGASAGQREG 1212
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 36.6 bits (83), Expect = 0.074
Identities = 28/116 (24%), Positives = 56/116 (48%), Gaps = 19/116 (16%)
Query: 493 KSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAED-------EKQRDKVSSKNSLESY 545
+S +E + + + R ++D ++E E+ K +D EK+R+K +
Sbjct: 358 RSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGK---- 413
Query: 546 AFNMKATVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELEK 601
N E EK + K ++D+++ +K +E K++ EKE+ + ++KE EK
Sbjct: 414 --NKDRDKEREKDREKDKEKDREREREKEHE------KDRDKEKEKEQDKEKEREK 461
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.132 0.369
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,216,302
Number of Sequences: 37866
Number of extensions: 1066086
Number of successful extensions: 5969
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 63
Number of HSP's successfully gapped in prelim test: 187
Number of HSP's that attempted gapping in prelim test: 5388
Number of HSP's gapped (non-prelim): 704
length of query: 646
length of database: 18,247,518
effective HSP length: 109
effective length of query: 537
effective length of database: 14,120,124
effective search space: 7582506588
effective search space used: 7582506588
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.