Search of human proteins with 5729838

Search of human proteins with 5729838

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5729838 glioma-amplified sequence-41 [Homo sapiens]
         (227 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5729838 glioma-amplified sequence-41 [Homo sapiens]                459   e-129
gi|33620755 YEATS domain containing 2 [Homo sapiens]                   87   2e-17
gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithor...    64   1e-10
gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithora...    61   9e-10
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho...    39   0.004
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho...    39   0.004
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho...    39   0.004
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho...    39   0.004
gi|51479166 bicaudal D homolog 2 isoform 1 [Homo sapiens]              39   0.005
gi|21735417 bicaudal D homolog 2 isoform 2 [Homo sapiens]              39   0.005
gi|62821790 leucine zipper protein 2 [Homo sapiens]                    37   0.011
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]    35   0.069
gi|51093830 bicaudal D homolog 1 isoform 2 [Homo sapiens]              34   0.090
gi|51039802 bicaudal D homolog 1 isoform 1 [Homo sapiens]              34   0.090
gi|33356148 formin-like 1 [Homo sapiens]                               33   0.15 
gi|109255234 centrosomal protein 290kDa [Homo sapiens]                 33   0.20 
gi|157671915 guanylate binding protein family, member 6 [Homo sa...    33   0.20 
gi|195947369 junction-mediating and regulatory protein [Homo sap...    33   0.26 
gi|63252900 tropomyosin 1 alpha chain isoform 4 [Homo sapiens]         32   0.34 
gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens]         32   0.34 
gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens]         32   0.34 
gi|27597085 tropomyosin 1 alpha chain isoform 5 [Homo sapiens]         32   0.34 
gi|19920317 cytoskeleton-associated protein 4 [Homo sapiens]           32   0.45 
gi|51972208 leucine, glutamate and lysine rich 1 [Homo sapiens]        32   0.58 
gi|115527097 CDC42-binding protein kinase beta [Homo sapiens]          32   0.58 
gi|154813191 IQ motif containing E isoform 1 [Homo sapiens]            32   0.58 
gi|154813193 IQ motif containing E isoform 2 [Homo sapiens]            32   0.58 
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]               31   0.76 
gi|226491199 coiled-coil domain containing 38 [Homo sapiens]           31   0.99 
gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens]                    31   0.99 

>gi|5729838 glioma-amplified sequence-41 [Homo sapiens]
          Length = 227

 Score =  459 bits (1180), Expect = e-129
 Identities = 227/227 (100%), Positives = 227/227 (100%)

Query: 1   MFKRMAEFGPDSGGRVKGVTIVKPIVYGNVARYFGKKREEDGHTHQWTVYVKPYRNEDMS 60
           MFKRMAEFGPDSGGRVKGVTIVKPIVYGNVARYFGKKREEDGHTHQWTVYVKPYRNEDMS
Sbjct: 1   MFKRMAEFGPDSGGRVKGVTIVKPIVYGNVARYFGKKREEDGHTHQWTVYVKPYRNEDMS 60

Query: 61  AYVKKIQFKLHESYGNPLRVVTKPPYEITETGWGEFEIIIKIFFIDPNERPVTLYHLLKL 120
           AYVKKIQFKLHESYGNPLRVVTKPPYEITETGWGEFEIIIKIFFIDPNERPVTLYHLLKL
Sbjct: 61  AYVKKIQFKLHESYGNPLRVVTKPPYEITETGWGEFEIIIKIFFIDPNERPVTLYHLLKL 120

Query: 121 FQSDTNAMLGKKTVVSEFYDEMIFQDPTAMMQQLLTTSRQLTLGAYKHETEFAELEVKTR 180
           FQSDTNAMLGKKTVVSEFYDEMIFQDPTAMMQQLLTTSRQLTLGAYKHETEFAELEVKTR
Sbjct: 121 FQSDTNAMLGKKTVVSEFYDEMIFQDPTAMMQQLLTTSRQLTLGAYKHETEFAELEVKTR 180

Query: 181 EKLEAAKKKTSFEIAELKERLKASRETINCLKNEIRKLEEDDQAKDI 227
           EKLEAAKKKTSFEIAELKERLKASRETINCLKNEIRKLEEDDQAKDI
Sbjct: 181 EKLEAAKKKTSFEIAELKERLKASRETINCLKNEIRKLEEDDQAKDI 227


>gi|33620755 YEATS domain containing 2 [Homo sapiens]
          Length = 1422

 Score = 86.7 bits (213), Expect = 2e-17
 Identities = 49/120 (40%), Positives = 72/120 (60%), Gaps = 5/120 (4%)

Query: 21  IVKPIVYGNVARYF--GKKREEDGHTHQWTVYVKPYRNE-DMSAYVKKIQFKLHESYG-N 76
           + K IV GNV++Y    K+ E D  TH+W VYV+  R E  ++ +VKK+ F LH SY  N
Sbjct: 206 VKKTIVVGNVSKYIPPDKREENDQSTHKWMVYVRGSRREPSINHFVKKVWFFLHPSYKPN 265

Query: 77  PLRVVTKPPYEITETGWGEFEIIIKIFFIDPNERPVTLYHLLKLFQSDTNAM-LGKKTVV 135
            L  V +PP+ +T  GWGEF + +++ F D   + + + H LKL ++ T    LG +TVV
Sbjct: 266 DLVEVREPPFHLTRRGWGEFPVRVQVHFKDSQNKRIDIIHNLKLDRTYTGLQTLGAETVV 325


>gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithorax
           homolog, Drosophila); translocated to, 3 [Homo sapiens]
          Length = 568

 Score = 63.5 bits (153), Expect = 1e-10
 Identities = 27/74 (36%), Positives = 46/74 (62%)

Query: 36  KKREEDGHTHQWTVYVKPYRNEDMSAYVKKIQFKLHESYGNPLRVVTKPPYEITETGWGE 95
           KK   +G TH W V+V+   + ++  +V+K+ F LHES+  P RV   PPY++ E+G+  
Sbjct: 21  KKPTVEGFTHDWMVFVRGPEHSNIQHFVEKVVFHLHESFPRPKRVCKDPPYKVEESGYAG 80

Query: 96  FEIIIKIFFIDPNE 109
           F + I+++F +  E
Sbjct: 81  FILPIEVYFKNKEE 94


>gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithorax
           homolog, Drosophila); translocated to, 1 [Homo sapiens]
          Length = 559

 Score = 60.8 bits (146), Expect = 9e-10
 Identities = 27/74 (36%), Positives = 45/74 (60%)

Query: 36  KKREEDGHTHQWTVYVKPYRNEDMSAYVKKIQFKLHESYGNPLRVVTKPPYEITETGWGE 95
           KK   +G TH W V+V+     D+  +V+K+ F LH+S+  P RV  +PPY++ E+G+  
Sbjct: 21  KKPTTEGFTHDWMVFVRGPEQCDIQHFVEKVVFWLHDSFPKPRRVCKEPPYKVEESGYAG 80

Query: 96  FEIIIKIFFIDPNE 109
           F + I++ F +  E
Sbjct: 81  FIMPIEVHFKNKEE 94


>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
            sapiens]
          Length = 1972

 Score = 38.9 bits (89), Expect = 0.004
 Identities = 34/111 (30%), Positives = 55/111 (49%), Gaps = 10/111 (9%)

Query: 120  LFQSDTNAMLGKKTVVSEFYDEMIFQDPTAMMQQLLTTSRQLTLGAYKHETEFAELEV-- 177
            L   D N  L K+  + E   E I  D T  + +    ++ LT    KHE+  +ELEV  
Sbjct: 988  LVMDDQNNKLSKERKLLE---ERI-SDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRL 1043

Query: 178  ----KTREKLEAAKKKTSFEIAELKERLKASRETINCLKNEIRKLEEDDQA 224
                K+R++LE  K+K   + ++  E++   +  I  LK ++ K EE+ QA
Sbjct: 1044 KKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQA 1094



 Score = 32.0 bits (71), Expect = 0.45
 Identities = 21/75 (28%), Positives = 37/75 (49%), Gaps = 1/75 (1%)

Query: 145  QDPTAMMQQLLTTSRQLTLGAYKHETEFAELEVKTREKLEAAKKKTSFEIAELKERLKAS 204
            +D  A   ++  T+++    A   E +  +L+ +     E A+K+   E  EL E L +S
Sbjct: 1662 EDARASRDEIFATAKENEKKAKSLEADLMQLQ-EDLAAAERARKQADLEKEELAEELASS 1720

Query: 205  RETINCLKNEIRKLE 219
                N L++E R+LE
Sbjct: 1721 LSGRNALQDEKRRLE 1735


>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
            sapiens]
          Length = 1979

 Score = 38.9 bits (89), Expect = 0.004
 Identities = 34/111 (30%), Positives = 55/111 (49%), Gaps = 10/111 (9%)

Query: 120  LFQSDTNAMLGKKTVVSEFYDEMIFQDPTAMMQQLLTTSRQLTLGAYKHETEFAELEV-- 177
            L   D N  L K+  + E   E I  D T  + +    ++ LT    KHE+  +ELEV  
Sbjct: 995  LVMDDQNNKLSKERKLLE---ERI-SDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRL 1050

Query: 178  ----KTREKLEAAKKKTSFEIAELKERLKASRETINCLKNEIRKLEEDDQA 224
                K+R++LE  K+K   + ++  E++   +  I  LK ++ K EE+ QA
Sbjct: 1051 KKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQA 1101



 Score = 32.0 bits (71), Expect = 0.45
 Identities = 21/75 (28%), Positives = 37/75 (49%), Gaps = 1/75 (1%)

Query: 145  QDPTAMMQQLLTTSRQLTLGAYKHETEFAELEVKTREKLEAAKKKTSFEIAELKERLKAS 204
            +D  A   ++  T+++    A   E +  +L+ +     E A+K+   E  EL E L +S
Sbjct: 1669 EDARASRDEIFATAKENEKKAKSLEADLMQLQ-EDLAAAERARKQADLEKEELAEELASS 1727

Query: 205  RETINCLKNEIRKLE 219
                N L++E R+LE
Sbjct: 1728 LSGRNALQDEKRRLE 1742


>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
            sapiens]
          Length = 1945

 Score = 38.9 bits (89), Expect = 0.004
 Identities = 34/111 (30%), Positives = 55/111 (49%), Gaps = 10/111 (9%)

Query: 120  LFQSDTNAMLGKKTVVSEFYDEMIFQDPTAMMQQLLTTSRQLTLGAYKHETEFAELEV-- 177
            L   D N  L K+  + E   E I  D T  + +    ++ LT    KHE+  +ELEV  
Sbjct: 995  LVMDDQNNKLSKERKLLE---ERI-SDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRL 1050

Query: 178  ----KTREKLEAAKKKTSFEIAELKERLKASRETINCLKNEIRKLEEDDQA 224
                K+R++LE  K+K   + ++  E++   +  I  LK ++ K EE+ QA
Sbjct: 1051 KKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQA 1101



 Score = 32.0 bits (71), Expect = 0.45
 Identities = 21/75 (28%), Positives = 37/75 (49%), Gaps = 1/75 (1%)

Query: 145  QDPTAMMQQLLTTSRQLTLGAYKHETEFAELEVKTREKLEAAKKKTSFEIAELKERLKAS 204
            +D  A   ++  T+++    A   E +  +L+ +     E A+K+   E  EL E L +S
Sbjct: 1669 EDARASRDEIFATAKENEKKAKSLEADLMQLQ-EDLAAAERARKQADLEKEELAEELASS 1727

Query: 205  RETINCLKNEIRKLE 219
                N L++E R+LE
Sbjct: 1728 LSGRNALQDEKRRLE 1742


>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
            sapiens]
          Length = 1938

 Score = 38.9 bits (89), Expect = 0.004
 Identities = 34/111 (30%), Positives = 55/111 (49%), Gaps = 10/111 (9%)

Query: 120  LFQSDTNAMLGKKTVVSEFYDEMIFQDPTAMMQQLLTTSRQLTLGAYKHETEFAELEV-- 177
            L   D N  L K+  + E   E I  D T  + +    ++ LT    KHE+  +ELEV  
Sbjct: 988  LVMDDQNNKLSKERKLLE---ERI-SDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRL 1043

Query: 178  ----KTREKLEAAKKKTSFEIAELKERLKASRETINCLKNEIRKLEEDDQA 224
                K+R++LE  K+K   + ++  E++   +  I  LK ++ K EE+ QA
Sbjct: 1044 KKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQA 1094



 Score = 32.0 bits (71), Expect = 0.45
 Identities = 21/75 (28%), Positives = 37/75 (49%), Gaps = 1/75 (1%)

Query: 145  QDPTAMMQQLLTTSRQLTLGAYKHETEFAELEVKTREKLEAAKKKTSFEIAELKERLKAS 204
            +D  A   ++  T+++    A   E +  +L+ +     E A+K+   E  EL E L +S
Sbjct: 1662 EDARASRDEIFATAKENEKKAKSLEADLMQLQ-EDLAAAERARKQADLEKEELAEELASS 1720

Query: 205  RETINCLKNEIRKLE 219
                N L++E R+LE
Sbjct: 1721 LSGRNALQDEKRRLE 1735


>gi|51479166 bicaudal D homolog 2 isoform 1 [Homo sapiens]
          Length = 855

 Score = 38.5 bits (88), Expect = 0.005
 Identities = 29/129 (22%), Positives = 58/129 (44%), Gaps = 21/129 (16%)

Query: 106 DPNERPVTLYHLLKLFQS---------DTNAMLGKKTVVSEFYDEMIFQDPTAMMQQLLT 156
           DP   P+ +Y+L+ + +          D    L ++ + S+     + +D  A+M+++L 
Sbjct: 619 DPRREPMNIYNLIAIIRDQIKHLQAAVDRTTELSRQRIASQELGPAVDKDKEALMEEILK 678

Query: 157 TSRQLTLGAYKHETEFAELEVKTREKLEAAKKKTSFEIAELKERLKASR----ETINCLK 212
               L+    +  T         R  L+A K+     +A LK + +  +    ET+  L+
Sbjct: 679 LKSLLSTKREQITT--------LRTVLKANKQTAEVALANLKSKYENEKAMVTETMMKLR 730

Query: 213 NEIRKLEED 221
           NE++ L+ED
Sbjct: 731 NELKALKED 739


>gi|21735417 bicaudal D homolog 2 isoform 2 [Homo sapiens]
          Length = 824

 Score = 38.5 bits (88), Expect = 0.005
 Identities = 29/129 (22%), Positives = 58/129 (44%), Gaps = 21/129 (16%)

Query: 106 DPNERPVTLYHLLKLFQS---------DTNAMLGKKTVVSEFYDEMIFQDPTAMMQQLLT 156
           DP   P+ +Y+L+ + +          D    L ++ + S+     + +D  A+M+++L 
Sbjct: 619 DPRREPMNIYNLIAIIRDQIKHLQAAVDRTTELSRQRIASQELGPAVDKDKEALMEEILK 678

Query: 157 TSRQLTLGAYKHETEFAELEVKTREKLEAAKKKTSFEIAELKERLKASR----ETINCLK 212
               L+    +  T         R  L+A K+     +A LK + +  +    ET+  L+
Sbjct: 679 LKSLLSTKREQITT--------LRTVLKANKQTAEVALANLKSKYENEKAMVTETMMKLR 730

Query: 213 NEIRKLEED 221
           NE++ L+ED
Sbjct: 731 NELKALKED 739


>gi|62821790 leucine zipper protein 2 [Homo sapiens]
          Length = 346

 Score = 37.4 bits (85), Expect = 0.011
 Identities = 22/88 (25%), Positives = 49/88 (55%), Gaps = 13/88 (14%)

Query: 143 IFQDPTAMMQQLLTTSRQL-----TLGAYKHETEFAELEV--------KTREKLEAAKKK 189
           +F++ + +++QL  TSR+L      L + K++ + A+ +V        K RE++++ ++ 
Sbjct: 34  VFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQREEMKSLQEA 93

Query: 190 TSFEIAELKERLKASRETINCLKNEIRK 217
              ++ E  E+ +  + TIN LK E+ +
Sbjct: 94  LQNQLKETSEKAEKHQATINFLKTEVER 121


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score = 34.7 bits (78), Expect = 0.069
 Identities = 18/48 (37%), Positives = 31/48 (64%)

Query: 176  EVKTREKLEAAKKKTSFEIAELKERLKASRETINCLKNEIRKLEEDDQ 223
            E KTR++LE AK+K   E  +L++++   +  I+ LK ++ K EE+ Q
Sbjct: 1046 EEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQ 1093


>gi|51093830 bicaudal D homolog 1 isoform 2 [Homo sapiens]
          Length = 835

 Score = 34.3 bits (77), Expect = 0.090
 Identities = 32/129 (24%), Positives = 60/129 (46%), Gaps = 21/129 (16%)

Query: 106 DPNERPVTLYHLLKLFQS---------DTNAMLGKKTVVSEFYDEMIFQDPTAMMQQLLT 156
           D  + P+ +Y+L  + +          D +  L ++   +     MI +D  A+M+++L 
Sbjct: 617 DIRKEPMNIYNLNAIIRDQIKHLQKAVDRSLQLSRQRAAARELAPMIDKDKEALMEEILK 676

Query: 157 TSRQLTLGAYKHETEFAELEVKTREKLEAAKKKTSFEIAELKERLKASR----ETINCLK 212
               L+    K E + A L    R  L+A K+     +A LK + +  +    ET+  L+
Sbjct: 677 LKSLLST---KRE-QIATL----RAVLKANKQTAEVALANLKNKYENEKAMVTETMTKLR 728

Query: 213 NEIRKLEED 221
           NE++ L+ED
Sbjct: 729 NELKALKED 737


>gi|51039802 bicaudal D homolog 1 isoform 1 [Homo sapiens]
          Length = 975

 Score = 34.3 bits (77), Expect = 0.090
 Identities = 32/129 (24%), Positives = 60/129 (46%), Gaps = 21/129 (16%)

Query: 106 DPNERPVTLYHLLKLFQS---------DTNAMLGKKTVVSEFYDEMIFQDPTAMMQQLLT 156
           D  + P+ +Y+L  + +          D +  L ++   +     MI +D  A+M+++L 
Sbjct: 617 DIRKEPMNIYNLNAIIRDQIKHLQKAVDRSLQLSRQRAAARELAPMIDKDKEALMEEILK 676

Query: 157 TSRQLTLGAYKHETEFAELEVKTREKLEAAKKKTSFEIAELKERLKASR----ETINCLK 212
               L+    K E + A L    R  L+A K+     +A LK + +  +    ET+  L+
Sbjct: 677 LKSLLST---KRE-QIATL----RAVLKANKQTAEVALANLKNKYENEKAMVTETMTKLR 728

Query: 213 NEIRKLEED 221
           NE++ L+ED
Sbjct: 729 NELKALKED 737


>gi|33356148 formin-like 1 [Homo sapiens]
          Length = 1100

 Score = 33.5 bits (75), Expect = 0.15
 Identities = 46/185 (24%), Positives = 78/185 (42%), Gaps = 39/185 (21%)

Query: 34  FGKKREEDGHTHQWTVYVKPYRNED-----MSAYVKKIQFKLHESYGNPLRVVTKPPYEI 88
           F   +E  G  H++   ++ +RNED     M A ++ I   +H       RV  +  YE 
Sbjct: 293 FDNFKEVCGEQHRFEKLMEYFRNEDSNIDFMVACMQFINIVVHSVENMNFRVFLQ--YEF 350

Query: 89  TETGWGEFEIIIKIFFIDPNERPVTLY-HLLKLFQSDTNAMLGKKTVVSEFYDEMIFQDP 147
           T  G                   + LY   L+L +SD      K  V  + Y + IF D 
Sbjct: 351 THLG-------------------LDLYLERLRLTESD------KLQVQIQAYLDNIF-DV 384

Query: 148 TAMMQQLLTTSRQLTLGAYKHETEFAELEVKTREKLEAAKKKTSFEIAELKERLKASRET 207
            A+++   T +  L     +H  E  E      E+L  A+ ++  +IAEL+++L  +R+ 
Sbjct: 385 GALLEDTETKNAVL-----EHMEELQEQVALLTERLRDAENESMAKIAELEKQLSQARKE 439

Query: 208 INCLK 212
           +  L+
Sbjct: 440 LETLR 444


>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
          Length = 2479

 Score = 33.1 bits (74), Expect = 0.20
 Identities = 16/50 (32%), Positives = 29/50 (58%)

Query: 171  EFAELEVKTREKLEAAKKKTSFEIAELKERLKASRETINCLKNEIRKLEE 220
            EF  ++++ +E  E   KK   E+ +LK  L  S++   CLK+E++  +E
Sbjct: 1664 EFENIKLQLQENHEDEVKKVKAEVEDLKYLLDQSQKESQCLKSELQAQKE 1713



 Score = 27.7 bits (60), Expect = 8.4
 Identities = 14/40 (35%), Positives = 25/40 (62%)

Query: 181  EKLEAAKKKTSFEIAELKERLKASRETINCLKNEIRKLEE 220
            ++L+    K S E  ELK +L+ + + +  LKN++R L+E
Sbjct: 2059 QELQKENLKLSSENIELKFQLEQANKDLPRLKNQVRDLKE 2098


>gi|157671915 guanylate binding protein family, member 6 [Homo
           sapiens]
          Length = 633

 Score = 33.1 bits (74), Expect = 0.20
 Identities = 24/103 (23%), Positives = 47/103 (45%), Gaps = 10/103 (9%)

Query: 132 KTVVSEFYDEMIFQDPTAMMQQLLTTSRQLTLGAYKHETEFAELEVKT--------REKL 183
           K V   F +  +  + + +      T R+  +   + + E AE E +         ++++
Sbjct: 457 KEVFQRFLESQMVIEESILQSDKALTDREKAVAVDRAKKEAAEKEQELLKQKLQEQQQQM 516

Query: 184 EAAKKKTSFEIAELKERLKASRETINCLKNEIRKLEEDDQAKD 226
           EA  K     IA+LKE+L+  RE  + L+ +I  LE   + ++
Sbjct: 517 EAQDKSRKENIAQLKEKLQMERE--HLLREQIMMLEHTQKVQN 557


>gi|195947369 junction-mediating and regulatory protein [Homo
           sapiens]
          Length = 988

 Score = 32.7 bits (73), Expect = 0.26
 Identities = 22/95 (23%), Positives = 47/95 (49%), Gaps = 8/95 (8%)

Query: 132 KTVVSEFYDEMIFQDPTAMMQQLLTTSRQLTLGAYKHETEFAELEVKTREKLEAAKKKTS 191
           K ++SE  DE+++ D    M+ +L    ++   AY    E  +L+ K R+ LEA + + S
Sbjct: 560 KRLISEKRDEVVYYDTYESMEAML-EKEEMAASAYLQREELQKLQQKARQ-LEARRGRVS 617

Query: 192 FEIAELKERLKASRETINCLKNEIRKLEEDDQAKD 226
            + + L+ + +       C+     K+++  + +D
Sbjct: 618 AKKSYLRNKKEI------CIAKHNEKIQQRTRIED 646


>gi|63252900 tropomyosin 1 alpha chain isoform 4 [Homo sapiens]
          Length = 284

 Score = 32.3 bits (72), Expect = 0.34
 Identities = 23/94 (24%), Positives = 47/94 (50%), Gaps = 7/94 (7%)

Query: 140 DEMIFQDPTAMMQQLLTTSRQLTLGAYKHETEFAELEVKTREKLEAAKKKTS---FEIAE 196
           D+   +D +  ++  L + ++   G      +++E     +EKLE A+KK +    ++A 
Sbjct: 28  DKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVAS 87

Query: 197 LKERLKASRETIN----CLKNEIRKLEEDDQAKD 226
           L  R++   E ++     L   ++KLEE ++A D
Sbjct: 88  LNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121


>gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens]
          Length = 284

 Score = 32.3 bits (72), Expect = 0.34
 Identities = 23/94 (24%), Positives = 47/94 (50%), Gaps = 7/94 (7%)

Query: 140 DEMIFQDPTAMMQQLLTTSRQLTLGAYKHETEFAELEVKTREKLEAAKKKTS---FEIAE 196
           D+   +D +  ++  L + ++   G      +++E     +EKLE A+KK +    ++A 
Sbjct: 28  DKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVAS 87

Query: 197 LKERLKASRETIN----CLKNEIRKLEEDDQAKD 226
           L  R++   E ++     L   ++KLEE ++A D
Sbjct: 88  LNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121


>gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens]
          Length = 284

 Score = 32.3 bits (72), Expect = 0.34
 Identities = 23/94 (24%), Positives = 47/94 (50%), Gaps = 7/94 (7%)

Query: 140 DEMIFQDPTAMMQQLLTTSRQLTLGAYKHETEFAELEVKTREKLEAAKKKTS---FEIAE 196
           D+   +D +  ++  L + ++   G      +++E     +EKLE A+KK +    ++A 
Sbjct: 28  DKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVAS 87

Query: 197 LKERLKASRETIN----CLKNEIRKLEEDDQAKD 226
           L  R++   E ++     L   ++KLEE ++A D
Sbjct: 88  LNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121


>gi|27597085 tropomyosin 1 alpha chain isoform 5 [Homo sapiens]
          Length = 284

 Score = 32.3 bits (72), Expect = 0.34
 Identities = 23/94 (24%), Positives = 47/94 (50%), Gaps = 7/94 (7%)

Query: 140 DEMIFQDPTAMMQQLLTTSRQLTLGAYKHETEFAELEVKTREKLEAAKKKTS---FEIAE 196
           D+   +D +  ++  L + ++   G      +++E     +EKLE A+KK +    ++A 
Sbjct: 28  DKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVAS 87

Query: 197 LKERLKASRETIN----CLKNEIRKLEEDDQAKD 226
           L  R++   E ++     L   ++KLEE ++A D
Sbjct: 88  LNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121


>gi|19920317 cytoskeleton-associated protein 4 [Homo sapiens]
          Length = 602

 Score = 32.0 bits (71), Expect = 0.45
 Identities = 19/57 (33%), Positives = 28/57 (49%)

Query: 169 ETEFAELEVKTREKLEAAKKKTSFEIAELKERLKASRETINCLKNEIRKLEEDDQAK 225
           E +F  LE    E+L    K  +  IA   E  K S++ IN +K ++  LEE +  K
Sbjct: 227 ERDFTSLENTVEERLTELTKSINDNIAIFTEVQKRSQKEINDMKAKVASLEESEGNK 283



 Score = 31.6 bits (70), Expect = 0.58
 Identities = 21/71 (29%), Positives = 36/71 (50%), Gaps = 1/71 (1%)

Query: 151 MQQLLTTSRQLTLGAYKHETEFAELEVKTREKLEAAKKKTSFEIAELKERLKASRETINC 210
           M+ L +T + +    Y    E   L+ + +   EAA  +    +  L E+L  S E+++ 
Sbjct: 307 MEALRSTLQTMESDIYTEVRELVSLKQEQQAFKEAADTER-LALQALTEKLLRSEESVSR 365

Query: 211 LKNEIRKLEED 221
           L  EIR+LEE+
Sbjct: 366 LPEEIRRLEEE 376


>gi|51972208 leucine, glutamate and lysine rich 1 [Homo sapiens]
          Length = 388

 Score = 31.6 bits (70), Expect = 0.58
 Identities = 24/88 (27%), Positives = 42/88 (47%), Gaps = 7/88 (7%)

Query: 137 EFYDE-MIFQDPTAMMQQLLTTSRQLTLGAYKHETEFAELEVKTREKLEAAKKKTSFEIA 195
           EF ++ ++F++ T +   +     Q  +  YK E E  EL++K  + +  A +    E+ 
Sbjct: 112 EFEEQALLFKEETKLQLDIEKEKHQDVIQKYKKEQE--ELQMKISDLITGATRDLRQEVT 169

Query: 196 ELKERLKASR----ETINCLKNEIRKLE 219
            LKE+L  S     E  N  + EI  L+
Sbjct: 170 TLKEKLHKSHTRYTEESNSKEKEIENLK 197


>gi|115527097 CDC42-binding protein kinase beta [Homo sapiens]
          Length = 1711

 Score = 31.6 bits (70), Expect = 0.58
 Identities = 14/50 (28%), Positives = 32/50 (64%), Gaps = 1/50 (2%)

Query: 171 EFAELEVKTREKLEAAKKKTSFEIAELKERLKASRETINCLKNEIRKLEE 220
           EF+EL  +  E L A K+K S ++ + +E ++ + + ++ ++ E+R+ E+
Sbjct: 576 EFSELNERMAE-LRAQKQKVSRQLRDKEEEMEVATQKVDAMRQEMRRAEK 624


>gi|154813191 IQ motif containing E isoform 1 [Homo sapiens]
          Length = 695

 Score = 31.6 bits (70), Expect = 0.58
 Identities = 12/34 (35%), Positives = 23/34 (67%)

Query: 193 EIAELKERLKASRETINCLKNEIRKLEEDDQAKD 226
           EI ELK+ L   +  ++ ++ ++R+LEE++  KD
Sbjct: 149 EIIELKKSLHVQKSDVDLMRTKLRRLEEENSRKD 182


>gi|154813193 IQ motif containing E isoform 2 [Homo sapiens]
          Length = 679

 Score = 31.6 bits (70), Expect = 0.58
 Identities = 12/34 (35%), Positives = 23/34 (67%)

Query: 193 EIAELKERLKASRETINCLKNEIRKLEEDDQAKD 226
           EI ELK+ L   +  ++ ++ ++R+LEE++  KD
Sbjct: 133 EIIELKKSLHVQKSDVDLMRTKLRRLEEENSRKD 166


>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
          Length = 1946

 Score = 31.2 bits (69), Expect = 0.76
 Identities = 21/77 (27%), Positives = 37/77 (48%), Gaps = 6/77 (7%)

Query: 151  MQQLLTTSRQLTLGAYKHETEFAELEVKTREK------LEAAKKKTSFEIAELKERLKAS 204
            M+ L ++ R L     K E E +++  K   +      L+   K+   +I +LKE+L+A 
Sbjct: 1078 MENLESSQRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAE 1137

Query: 205  RETINCLKNEIRKLEED 221
            R T   ++ E   L +D
Sbjct: 1138 RTTRAKMERERADLTQD 1154


>gi|226491199 coiled-coil domain containing 38 [Homo sapiens]
          Length = 563

 Score = 30.8 bits (68), Expect = 0.99
 Identities = 24/80 (30%), Positives = 40/80 (50%), Gaps = 7/80 (8%)

Query: 142 MIFQDPTAMMQQLLTTSRQ-LTLGAYKHETEFAELEVKTREKLEAAKKKTSFE-IAELKE 199
           + F++P  ++Q L     Q LTL  Y  + +    EV  REK+   K  ++ E + E ++
Sbjct: 334 LYFKEPEELLQVLRELEEQNLTLFQYSQDVDENLEEVNKREKVIQDKTNSNIEFLLEQEK 393

Query: 200 RLKASRETINCLKNEIRKLE 219
            LKA     NC++ E +  E
Sbjct: 394 MLKA-----NCVREEEKAAE 408


>gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens]
          Length = 284

 Score = 30.8 bits (68), Expect = 0.99
 Identities = 24/94 (25%), Positives = 46/94 (48%), Gaps = 7/94 (7%)

Query: 140 DEMIFQDPTAMMQQLLTTSRQLTLGAYKHETEFAELEVKTREKLEAAKKKTS---FEIAE 196
           D+   +D    +++ LT  ++   G      +++E     +EKLE  +KK S    ++A 
Sbjct: 28  DKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYSEDLKDAQEKLELTEKKASDAEGDVAA 87

Query: 197 LKERLKASRETIN----CLKNEIRKLEEDDQAKD 226
           L  R++   E ++     L   ++KLEE ++A D
Sbjct: 88  LNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.135    0.385 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,095,096
Number of Sequences: 37866
Number of extensions: 334493
Number of successful extensions: 1864
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 40
Number of HSP's successfully gapped in prelim test: 90
Number of HSP's that attempted gapping in prelim test: 1688
Number of HSP's gapped (non-prelim): 276
length of query: 227
length of database: 18,247,518
effective HSP length: 99
effective length of query: 128
effective length of database: 14,498,784
effective search space: 1855844352
effective search space used: 1855844352
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.