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Search of human proteins with 5729756
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5729756 voltage-dependent calcium channel gamma-3 subunit
[Homo sapiens]
(315 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5729756 voltage-dependent calcium channel gamma-3 subunit [Ho... 637 0.0
gi|5174405 voltage-dependent calcium channel gamma-2 subunit [Ho... 478 e-135
gi|7656948 voltage-dependent calcium channel gamma-4 subunit [Ho... 358 3e-99
gi|24586686 voltage-dependent calcium channel gamma-8 subunit [H... 329 2e-90
gi|22027551 voltage-dependent calcium channel gamma-5 subunit is... 118 6e-27
gi|21361975 voltage-dependent calcium channel gamma-7 subunit [H... 109 4e-24
gi|7656950 voltage-dependent calcium channel gamma-5 subunit iso... 109 4e-24
gi|239756473 PREDICTED: transmembrane protein 114 [Homo sapiens] 55 8e-08
gi|226437592 transmembrane protein 114 [Homo sapiens] 55 8e-08
gi|239752599 PREDICTED: transmembrane protein 114, partial [Homo... 53 3e-07
gi|169211272 PREDICTED: germ cell-specific gene 1-like protein 2... 44 2e-04
gi|169211660 PREDICTED: germ cell-specific gene 1-like protein 2... 44 2e-04
gi|169210878 PREDICTED: germ cell-specific gene 1-like protein 2... 44 2e-04
gi|157951718 GSG1-like isoform 1 [Homo sapiens] 41 0.002
gi|239916002 lens intrinsic membrane protein 2, 19kDa isoform 2 ... 38 0.010
gi|4502539 voltage-dependent calcium channel gamma-1 subunit [Ho... 38 0.013
gi|4502877 claudin 4 [Homo sapiens] 37 0.023
gi|153792768 claudin 6 [Homo sapiens] 36 0.051
gi|239745400 PREDICTED: transmembrane protein 114 [Homo sapiens] 36 0.051
gi|7705961 claudin 18 isoform 1 [Homo sapiens] 36 0.051
gi|5921465 claudin 10 isoform b [Homo sapiens] 35 0.087
gi|50345279 claudin 18 isoform 2 [Homo sapiens] 35 0.087
gi|123317881 germ cell associated 1 isoform 4 [Homo sapiens] 34 0.15
gi|123317861 germ cell associated 1 isoform 2 [Homo sapiens] 34 0.15
gi|11141861 claudin 9 [Homo sapiens] 34 0.19
gi|4503559 epithelial membrane protein 1 [Homo sapiens] 33 0.33
gi|47716519 claudin 20 [Homo sapiens] 33 0.33
gi|21361300 lens intrinsic membrane protein 2, 19kDa isoform 1 [... 32 0.56
gi|33598916 claudin 10 isoform a [Homo sapiens] 32 0.56
gi|9558733 transformer-2 alpha [Homo sapiens] 32 0.73
>gi|5729756 voltage-dependent calcium channel gamma-3 subunit [Homo
sapiens]
Length = 315
Score = 637 bits (1642), Expect = 0.0
Identities = 315/315 (100%), Positives = 315/315 (100%)
Query: 1 MRMCDRGIQMLITTVGAFAAFSLMTIAVGTDYWLYSRGVCRTKSTSDNETSRKNEEVMTH 60
MRMCDRGIQMLITTVGAFAAFSLMTIAVGTDYWLYSRGVCRTKSTSDNETSRKNEEVMTH
Sbjct: 1 MRMCDRGIQMLITTVGAFAAFSLMTIAVGTDYWLYSRGVCRTKSTSDNETSRKNEEVMTH 60
Query: 61 SGLWRTCCLEGAFRGVCKKIDHFPEDADYEQDTAEYLLRAVRASSVFPILSVTLLFFGGL 120
SGLWRTCCLEGAFRGVCKKIDHFPEDADYEQDTAEYLLRAVRASSVFPILSVTLLFFGGL
Sbjct: 61 SGLWRTCCLEGAFRGVCKKIDHFPEDADYEQDTAEYLLRAVRASSVFPILSVTLLFFGGL 120
Query: 121 CVAASEFHRSRHNVILSAGIFFVSAGLSNIIGIIVYISANAGDPGQRDSKKSYSYGWSFY 180
CVAASEFHRSRHNVILSAGIFFVSAGLSNIIGIIVYISANAGDPGQRDSKKSYSYGWSFY
Sbjct: 121 CVAASEFHRSRHNVILSAGIFFVSAGLSNIIGIIVYISANAGDPGQRDSKKSYSYGWSFY 180
Query: 181 FGAFSFIIAEIVGVVAVHIYIEKHQQLRAKSHSEFLKKSTFARLPPYRYRFRRRSSSRST 240
FGAFSFIIAEIVGVVAVHIYIEKHQQLRAKSHSEFLKKSTFARLPPYRYRFRRRSSSRST
Sbjct: 181 FGAFSFIIAEIVGVVAVHIYIEKHQQLRAKSHSEFLKKSTFARLPPYRYRFRRRSSSRST 240
Query: 241 EPRSRDLSPISKGFHTIPSTDISMFTLSRDPSKITMGTLLNSDRDHAFLQFHNSTPKEFK 300
EPRSRDLSPISKGFHTIPSTDISMFTLSRDPSKITMGTLLNSDRDHAFLQFHNSTPKEFK
Sbjct: 241 EPRSRDLSPISKGFHTIPSTDISMFTLSRDPSKITMGTLLNSDRDHAFLQFHNSTPKEFK 300
Query: 301 ESLHNNPANRRTTPV 315
ESLHNNPANRRTTPV
Sbjct: 301 ESLHNNPANRRTTPV 315
>gi|5174405 voltage-dependent calcium channel gamma-2 subunit [Homo
sapiens]
Length = 323
Score = 478 bits (1230), Expect = e-135
Identities = 241/323 (74%), Positives = 281/323 (86%), Gaps = 8/323 (2%)
Query: 1 MRMCDRGIQMLITTVGAFAAFSLMTIAVGTDYWLYSRGVCRTKSTSDNETSRKNEEVMTH 60
M + DRG+QML+TTVGAFAAFSLMTIAVGTDYWLYSRGVC+TKS S+NETS+KNEEVMTH
Sbjct: 1 MGLFDRGVQMLLTTVGAFAAFSLMTIAVGTDYWLYSRGVCKTKSVSENETSKKNEEVMTH 60
Query: 61 SGLWRTCCLEGAFRGVCKKIDHFPEDADYEQDTAEYLLRAVRASSVFPILSVTLLFFGGL 120
SGLWRTCCLEG F+G+CK+IDHFPEDADYE DTAEY LRAVRASS+FPILSV LLF GGL
Sbjct: 61 SGLWRTCCLEGNFKGLCKQIDHFPEDADYEADTAEYFLRAVRASSIFPILSVILLFMGGL 120
Query: 121 CVAASEFHRSRHNVILSAGIFFVSAGLSNIIGIIVYISANAGDPGQRDSKK-SYSYGWSF 179
C+AASEF+++RHN+ILSAGIFFVSAGLSNIIGIIVYISANAGDP + DSKK SYSYGWSF
Sbjct: 121 CIAASEFYKTRHNIILSAGIFFVSAGLSNIIGIIVYISANAGDPSKSDSKKNSYSYGWSF 180
Query: 180 YFGAFSFIIAEIVGVVAVHIYIEKHQQLRAKSH-SEFLKKSTFARLPPYRYRFRR--RSS 236
YFGA SFIIAE+VGV+AVH++I++H+QLRA + +++L+ S R+P YRYR++R RSS
Sbjct: 181 YFGALSFIIAEMVGVLAVHMFIDRHKQLRATARATDYLQASAITRIPSYRYRYQRRSRSS 240
Query: 237 SRSTEP-RSRDLSPIS-KGFHTIPSTDISMFTLSRDPSK--ITMGTLLNSDRDHAFLQFH 292
SRSTEP SRD SP+ KGF+T+PST+ISM+TLSRDP K T NSDRD++FLQ H
Sbjct: 241 SRSTEPSHSRDASPVGIKGFNTLPSTEISMYTLSRDPLKAATTPTATYNSDRDNSFLQVH 300
Query: 293 NSTPKEFKESLHNNPANRRTTPV 315
N KE K+SLH+N ANRRTTPV
Sbjct: 301 NCIQKENKDSLHSNTANRRTTPV 323
>gi|7656948 voltage-dependent calcium channel gamma-4 subunit [Homo
sapiens]
Length = 327
Score = 358 bits (920), Expect = 3e-99
Identities = 187/327 (57%), Positives = 238/327 (72%), Gaps = 12/327 (3%)
Query: 1 MRMCDRGIQMLITTVGAFAAFSLMTIAVGTDYWLYSRG-VCRTKSTS--DNETSRKNEEV 57
M CDRG+QML+TT GAFAAFSLM IA+GTDYWLYS +C + + D R+
Sbjct: 1 MVRCDRGLQMLLTTAGAFAAFSLMAIAIGTDYWLYSSAHICNGTNLTMDDGPPPRRARGD 60
Query: 58 MTHSGLWRTCCLEGAFRGVCKKIDHFPEDADYEQDTAEYLLRAVRASSVFPILSVTLLFF 117
+THSGLWR CC+EG ++G C +I+HFPED DY+ D++EYLLR VRASSVFPILS LL
Sbjct: 61 LTHSGLWRVCCIEGIYKGHCFRINHFPEDNDYDHDSSEYLLRIVRASSVFPILSTILLLL 120
Query: 118 GGLCVAASEFHRSRHNVILSAGIFFVSAGLSNIIGIIVYISANAGDPGQR---DSKKSYS 174
GGLC+ A + ++N++LSAGI FV+AGLSNIIGIIVYIS+N GDP + D K Y+
Sbjct: 121 GGLCIGAGRIYSRKNNIVLSAGILFVAAGLSNIIGIIVYISSNTGDPSDKRDEDKKNHYN 180
Query: 175 YGWSFYFGAFSFIIAEIVGVVAVHIYIEKHQQLRAKSHSEFLKKST---FARLPPYRYRF 231
YGWSFYFGA SFI+AE VGV+AV+IYIEK+++LR K+ EFLK S+ +AR+P YRYR
Sbjct: 181 YGWSFYFGALSFIVAETVGVLAVNIYIEKNKELRFKTKREFLKASSSSPYARMPSYRYRR 240
Query: 232 RR-RSSSRSTEPR-SRDLSPIS-KGFHTIPSTDISMFTLSRDPSKITMGTLLNSDRDHAF 288
RR RSSSRSTE SRD+SP+ K IP ++SM+TLSR+P K+T + D++ +F
Sbjct: 241 RRSRSSSRSTEASPSRDVSPMGLKITGAIPMGELSMYTLSREPLKVTTAASYSPDQEASF 300
Query: 289 LQFHNSTPKEFKESLHNNPANRRTTPV 315
LQ H+ ++ KE H + NRRTTPV
Sbjct: 301 LQVHDFFQQDLKEGFHVSMLNRRTTPV 327
>gi|24586686 voltage-dependent calcium channel gamma-8 subunit [Homo
sapiens]
Length = 425
Score = 329 bits (844), Expect = 2e-90
Identities = 172/301 (57%), Positives = 214/301 (71%), Gaps = 31/301 (10%)
Query: 4 CDRGIQMLITTVGAFAAFSLMTIAVGTDYWLYSRG-VCRTKSTS------------DNET 50
C++G+Q+L+TTVGAFAAF LMTIA+ TDYWLY+R +C T + + +
Sbjct: 15 CEKGVQVLLTTVGAFAAFGLMTIAISTDYWLYTRALICNTTNLTAGGDDGTPHRGGGGAS 74
Query: 51 SRKNEEVMTHSGLWRTCCLEGAFRGVCKKIDHFPEDADYEQDTAEYLLRAVRASSVFPIL 110
+K+ +THSGLWR CCLEG RGVC KI+HFPED DY+ D+AEYLLR VRASS+FPIL
Sbjct: 75 EKKDPGGLTHSGLWRICCLEGLKRGVCVKINHFPEDTDYDHDSAEYLLRVVRASSIFPIL 134
Query: 111 SVTLLFFGGLCVAASEFHRSRHNVILSAGIFFVSAGLSNIIGIIVYISANAGDPGQR--- 167
S LL GG+CVAAS ++S+ N+IL AGI FV+AGLSNIIG+IVYISANAG+PG +
Sbjct: 135 SAILLLLGGVCVAASRVYKSKRNIILGAGILFVAAGLSNIIGVIVYISANAGEPGPKRDE 194
Query: 168 DSKKSYSYGWSFYFGAFSFIIAEIVGVVAVHIYIEKHQQLRAKSHSEFLK---------- 217
+ K YSYGWSFYFG SFI+AE++GV+AV+IYIE+ ++ +S S+ LK
Sbjct: 195 EKKNHYSYGWSFYFGGLSFILAEVIGVLAVNIYIERSREAHCQSRSDLLKAGGGAGGSGG 254
Query: 218 --KSTFARLPPYRYRFRR--RSSSRSTEPR-SRDLSPISKGFHTIPSTDISMFTLSRDPS 272
S RLP YR+R+RR RSSSRS+EP SRD SP G STDISM+TLSRDPS
Sbjct: 255 SGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFASTDISMYTLSRDPS 314
Query: 273 K 273
K
Sbjct: 315 K 315
>gi|22027551 voltage-dependent calcium channel gamma-5 subunit
isoform a [Homo sapiens]
Length = 275
Score = 118 bits (296), Expect = 6e-27
Identities = 67/210 (31%), Positives = 116/210 (55%), Gaps = 12/210 (5%)
Query: 1 MRMCDRGIQMLITTVGAFAAFSLMTIAVGTDYWLY-SRGVCRTKSTSDNETSRKNEEVMT 59
M C R L+++V A L+ IAV TDYWLY GV ++ S ++
Sbjct: 1 MSACGRKALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGVIVPQNQSTEI------KMSL 54
Query: 60 HSGLWRTCCLEGAFRGVCKKIDH-FPEDADYEQDTAEYLLRAVRASSVFPILSVTLLFFG 118
HSGLWR C L G RG C I++ P + ++ +L+ +R+++ FP++S+ +F G
Sbjct: 55 HSGLWRVCFLAGEERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIG 114
Query: 119 GLCVAASEFHRSRHNVILSAGIFFVSAGLSNIIGIIVYISANAGDPGQR----DSKKSYS 174
+ R + +GIFF+ +GLS ++G+++YIS+ + R ++ +Y
Sbjct: 115 FILNNIGHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYK 174
Query: 175 YGWSFYFGAFSFIIAEIVGVVAVHIYIEKH 204
YGWSF F A SF++ E GV++V+++++++
Sbjct: 175 YGWSFAFAAISFLLTESAGVMSVYLFMKRY 204
>gi|21361975 voltage-dependent calcium channel gamma-7 subunit [Homo
sapiens]
Length = 275
Score = 109 bits (272), Expect = 4e-24
Identities = 63/211 (29%), Positives = 109/211 (51%), Gaps = 10/211 (4%)
Query: 1 MRMCDRGIQMLITTVGAFAAFSLMTIAVGTDYWLYSRGVCRTKSTSDNETSRKNEEVMTH 60
M C L+++V L+ IAV TDYWLY + T + ++ H
Sbjct: 1 MSHCSSRALTLLSSVFGACGLLLVGIAVSTDYWLYME-----EGTVLPQNQTTEVKMALH 55
Query: 61 SGLWRTCCLEGAFRGVCKKIDHFPE-DADYEQDTAEYLLRAVRASSVFPILSVTLLFFGG 119
+GLWR C G +G C ++F E + + + E +L+ VR ++ FP++S+ L+F
Sbjct: 56 AGLWRVCFFAGREKGRCVASEYFLEPEINLVTENTENILKTVRTATPFPMVSLFLVFTAF 115
Query: 120 LCVAASEFHRSRHNVILSAGIFFVSAGLSNIIGIIVYISANAGDPGQRDSKKS----YSY 175
+ R + +GIFF+ +GLS ++G+++YIS+ + R S Y Y
Sbjct: 116 VISNIGHIRPQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPSSSEQYFHYRY 175
Query: 176 GWSFYFGAFSFIIAEIVGVVAVHIYIEKHQQ 206
GWSF F A SF++ E GV++V+++ +++ +
Sbjct: 176 GWSFAFAASSFLLKEGAGVMSVYLFTKRYAE 206
>gi|7656950 voltage-dependent calcium channel gamma-5 subunit
isoform b [Homo sapiens]
Length = 296
Score = 109 bits (272), Expect = 4e-24
Identities = 64/197 (32%), Positives = 105/197 (53%), Gaps = 12/197 (6%)
Query: 1 MRMCDRGIQMLITTVGAFAAFSLMTIAVGTDYWLY-SRGVCRTKSTSDNETSRKNEEVMT 59
M C R L+++V A L+ IAV TDYWLY GV ++ S ++
Sbjct: 1 MSACGRKALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGVIVPQNQSTEI------KMSL 54
Query: 60 HSGLWRTCCLEGAFRGVCKKIDH-FPEDADYEQDTAEYLLRAVRASSVFPILSVTLLFFG 118
HSGLWR C L G RG C I++ P + ++ +L+ +R+++ FP++S+ +F G
Sbjct: 55 HSGLWRVCFLAGEERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIG 114
Query: 119 GLCVAASEFHRSRHNVILSAGIFFVSAGLSNIIGIIVYISANAGDPGQR----DSKKSYS 174
+ R + +GIFF+ +GLS ++G+++YIS+ + R ++ +Y
Sbjct: 115 FILNNIGHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYK 174
Query: 175 YGWSFYFGAFSFIIAEI 191
YGWSF F A SF++ E+
Sbjct: 175 YGWSFAFAAISFLLTEV 191
>gi|239756473 PREDICTED: transmembrane protein 114 [Homo sapiens]
Length = 223
Score = 55.1 bits (131), Expect = 8e-08
Identities = 54/208 (25%), Positives = 92/208 (44%), Gaps = 20/208 (9%)
Query: 1 MRMCDRGIQMLITTVGAFAAFSLMTIAVGTDYW--LYSRGVCRTKSTSDNETSRKN---- 54
MR+ G+ GA + F L+ A+GTD+W + + + RT + + N
Sbjct: 1 MRVHLGGLAGAAALTGALS-FVLLAAAIGTDFWYIIDTERLERTGPGAQDLLGSINRSQP 59
Query: 55 EEVMTHSGLWRTCCLEGAFRGVCKKIDHFPEDADYEQDTAEYLLRAVRASSVFPILSVTL 114
E + +HSGLWRTC ++ + ++ F + +++ LL + LS+ L
Sbjct: 60 EPLSSHSGLWRTCRVQSPCTPL---MNPFRLENVTVSESSRQLLTMHGTFVILLPLSLIL 116
Query: 115 LFFGGLCVAASEFHRSRHNVILSAGIFFVSAGLSNIIGIIVYISANAG---------DPG 165
+ FGG+ S F + ++L GI F+ + + GI VYI+ +A +
Sbjct: 117 MVFGGMTGFLS-FLLQAYLLLLLTGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEK 175
Query: 166 QRDSKKSYSYGWSFYFGAFSFIIAEIVG 193
+ S+GWS G SFI + G
Sbjct: 176 ALLDQVDISFGWSLALGWISFIAELLTG 203
>gi|226437592 transmembrane protein 114 [Homo sapiens]
Length = 223
Score = 55.1 bits (131), Expect = 8e-08
Identities = 54/208 (25%), Positives = 92/208 (44%), Gaps = 20/208 (9%)
Query: 1 MRMCDRGIQMLITTVGAFAAFSLMTIAVGTDYW--LYSRGVCRTKSTSDNETSRKN---- 54
MR+ G+ GA + F L+ A+GTD+W + + + RT + + N
Sbjct: 1 MRVHLGGLAGAAALTGALS-FVLLAAAIGTDFWYIIDTERLERTGPGAQDLLGSINRSQP 59
Query: 55 EEVMTHSGLWRTCCLEGAFRGVCKKIDHFPEDADYEQDTAEYLLRAVRASSVFPILSVTL 114
E + +HSGLWRTC ++ + ++ F + +++ LL + LS+ L
Sbjct: 60 EPLSSHSGLWRTCRVQSPCTPL---MNPFRLENVTVSESSRQLLTMHGTFVILLPLSLIL 116
Query: 115 LFFGGLCVAASEFHRSRHNVILSAGIFFVSAGLSNIIGIIVYISANAG---------DPG 165
+ FGG+ S F + ++L GI F+ + + GI VYI+ +A +
Sbjct: 117 MVFGGMTGFLS-FLLQAYLLLLLTGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEK 175
Query: 166 QRDSKKSYSYGWSFYFGAFSFIIAEIVG 193
+ S+GWS G SFI + G
Sbjct: 176 ALLDQVDISFGWSLALGWISFIAELLTG 203
>gi|239752599 PREDICTED: transmembrane protein 114, partial [Homo
sapiens]
Length = 217
Score = 53.1 bits (126), Expect = 3e-07
Identities = 48/189 (25%), Positives = 85/189 (44%), Gaps = 19/189 (10%)
Query: 20 AFSLMTIAVGTDYW--LYSRGVCRTKSTSDNETSRKN----EEVMTHSGLWRTCCLEGAF 73
+F L+ A+GT++W + + + RT + + N E + +HSGLWRTC ++
Sbjct: 13 SFVLLAAAIGTEFWYIIDTERLERTGPGAQDLLGSINRSQPEPLSSHSGLWRTCRVQSPC 72
Query: 74 RGVCKKIDHFPEDADYEQDTAEYLLRAVRASSVFPILSVTLLFFGGLCVAASEFHRSRHN 133
+ ++ F + +++ LL + LS+ L+ FGG+ S F +
Sbjct: 73 TPL---MNPFRLENVTVSESSRQLLTMHGTFVILLPLSLILMVFGGMTGFLS-FLLQAYL 128
Query: 134 VILSAGIFFVSAGLSNIIGIIVYISANAG---------DPGQRDSKKSYSYGWSFYFGAF 184
++L GI F+ + + GI VYI+ +A + + S+GWS G
Sbjct: 129 LLLLTGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKALLDQVDISFGWSLALGWI 188
Query: 185 SFIIAEIVG 193
SFI + G
Sbjct: 189 SFIAELLTG 197
>gi|169211272 PREDICTED: germ cell-specific gene 1-like protein
2-like [Homo sapiens]
Length = 293
Score = 43.5 bits (101), Expect = 2e-04
Identities = 41/167 (24%), Positives = 70/167 (41%), Gaps = 18/167 (10%)
Query: 60 HSGLWRTCCLEGAFRGVCKKIDHFPEDADYEQDTAEYLLRAVRASSVFPILSVTLLFFGG 119
H GLW++C E + G +K F E+ +L + IL+ +L
Sbjct: 89 HVGLWQSC--EESLNGEDEKCRSFRSVVPAEEQGVLWLSIGGEVLDIVLILTSAILLGSR 146
Query: 120 LCVAASEFHRSRHNVILSAGIFFVSAGLSNIIGIIVY-----ISANAGDPGQRDSKKSYS 174
+ + FH R + +++ IF V AGL ++ ++Y I+ N G + +++
Sbjct: 147 VSCRSPGFHWLRVDALVA--IFMVLAGLLGMVAHMMYTTIFQITVNLGPEDWKP--QTWD 202
Query: 175 YGWSFYFGAFSFIIAEIVGVVAVH-------IYIEKHQQLRAKSHSE 214
YGWS+ SF + V V A+ + EK Q HS+
Sbjct: 203 YGWSYCLAWGSFALCLAVSVSAMSRFTAARLEFTEKQQAQNGSRHSQ 249
>gi|169211660 PREDICTED: germ cell-specific gene 1-like protein
2-like [Homo sapiens]
Length = 293
Score = 43.5 bits (101), Expect = 2e-04
Identities = 41/167 (24%), Positives = 70/167 (41%), Gaps = 18/167 (10%)
Query: 60 HSGLWRTCCLEGAFRGVCKKIDHFPEDADYEQDTAEYLLRAVRASSVFPILSVTLLFFGG 119
H GLW++C E + G +K F E+ +L + IL+ +L
Sbjct: 89 HVGLWQSC--EESLNGEDEKCRSFRSVVPAEEQGVLWLSIGGEVLDIVLILTSAILLGSR 146
Query: 120 LCVAASEFHRSRHNVILSAGIFFVSAGLSNIIGIIVY-----ISANAGDPGQRDSKKSYS 174
+ + FH R + +++ IF V AGL ++ ++Y I+ N G + +++
Sbjct: 147 VSCRSPGFHWLRVDALVA--IFMVLAGLLGMVAHMMYTTIFQITVNLGPEDWKP--QTWD 202
Query: 175 YGWSFYFGAFSFIIAEIVGVVAVH-------IYIEKHQQLRAKSHSE 214
YGWS+ SF + V V A+ + EK Q HS+
Sbjct: 203 YGWSYCLAWGSFALCLAVSVSAMSRFTAARLEFTEKQQAQNGSRHSQ 249
>gi|169210878 PREDICTED: germ cell-specific gene 1-like protein
2-like [Homo sapiens]
Length = 293
Score = 43.5 bits (101), Expect = 2e-04
Identities = 41/167 (24%), Positives = 70/167 (41%), Gaps = 18/167 (10%)
Query: 60 HSGLWRTCCLEGAFRGVCKKIDHFPEDADYEQDTAEYLLRAVRASSVFPILSVTLLFFGG 119
H GLW++C E + G +K F E+ +L + IL+ +L
Sbjct: 89 HVGLWQSC--EESLNGEDEKCRSFRSVVPAEEQGVLWLSIGGEVLDIVLILTSAILLGSR 146
Query: 120 LCVAASEFHRSRHNVILSAGIFFVSAGLSNIIGIIVY-----ISANAGDPGQRDSKKSYS 174
+ + FH R + +++ IF V AGL ++ ++Y I+ N G + +++
Sbjct: 147 VSCRSPGFHWLRVDALVA--IFMVLAGLLGMVAHMMYTTIFQITVNLGPEDWKP--QTWD 202
Query: 175 YGWSFYFGAFSFIIAEIVGVVAVH-------IYIEKHQQLRAKSHSE 214
YGWS+ SF + V V A+ + EK Q HS+
Sbjct: 203 YGWSYCLAWGSFALCLAVSVSAMSRFTAARLEFTEKQQAQNGSRHSQ 249
>gi|157951718 GSG1-like isoform 1 [Homo sapiens]
Length = 331
Score = 40.8 bits (94), Expect = 0.002
Identities = 49/193 (25%), Positives = 78/193 (40%), Gaps = 27/193 (13%)
Query: 60 HSGLWRTCCLEGAFRGVCKKIDHFPEDADYEQDTAEYLLRAVRASSVFPILSVTLLFFGG 119
H+G+W +C E G+ +K F + A + +L S V +L + LL G
Sbjct: 102 HTGIWYSC--EEELSGLGEKCRSFIDLAPASEKGVLWL------SVVSEVLYILLLVVGF 153
Query: 120 LCVAASEFHRSRHNVI------LSAGIFFVSAGLSNIIGIIVY-----ISANAGDPGQRD 168
+ FH S NVI A +F V +GL ++ ++Y ++ + G R
Sbjct: 154 SLMCLELFHSS--NVIDGLKLNAFAAVFTVLSGLLGMVAHMMYTQVFQVTVSLGPEDWRP 211
Query: 169 SKKSYSYGWSFYFGAFSFIIAEIVGVVAVHIYIEKHQQLRAKS---HSEFLKKSTFARLP 225
S+ YGWSF SF V ++ Y + + R K + ++ TF
Sbjct: 212 H--SWDYGWSFCLAWGSFTCCMAASVTTLNSYTKTVIEFRHKRKVFEQGYREEPTFIDPE 269
Query: 226 PYRYRFRRRSSSR 238
+Y FR R R
Sbjct: 270 AIKY-FRERMEKR 281
>gi|239916002 lens intrinsic membrane protein 2, 19kDa isoform 2
[Homo sapiens]
Length = 173
Score = 38.1 bits (87), Expect = 0.010
Identities = 40/187 (21%), Positives = 67/187 (35%), Gaps = 40/187 (21%)
Query: 17 AFAAFSLMTIAVGTDYWLYSRGVCRTKSTSDNETSRKNEEVMTHSGLWRTCCLEGAFRGV 76
A+ L+ +A+ TD+W+ R H GLWR C +
Sbjct: 12 AWVGTILLVVAMATDHWMQYR----------------LSGSFAHQGLWRYCLGNKCY--- 52
Query: 77 CKKIDHFPEDADYEQDTAEYLLRAVRASSVFPILSVTLLFFG---GLCVAASEFHRSRHN 133
+ D+ Y A+ F ILS G G+ A + SR +
Sbjct: 53 ------------LQTDSIAYW----NATRAFMILSALCAISGIIMGIMAFAHQPTFSRIS 96
Query: 134 VILSAGIFFVSAGLSNIIGIIVYISANAGDPGQRDSKKSYSYGWSFYFGAFSFIIAEIVG 193
SAGI F S+ L ++ + +Y G+R + + WS+ G + ++ G
Sbjct: 97 RPFSAGIMFFSSTLFVVLALAIYTGVTVSFLGRRFG--DWRFSWSYILGWVAVLMTFFAG 154
Query: 194 VVAVHIY 200
+ + Y
Sbjct: 155 IFYMCAY 161
>gi|4502539 voltage-dependent calcium channel gamma-1 subunit [Homo
sapiens]
Length = 222
Score = 37.7 bits (86), Expect = 0.013
Identities = 50/205 (24%), Positives = 76/205 (37%), Gaps = 32/205 (15%)
Query: 8 IQMLITTVGAFAAFSLMTIAVGTDYWLYSRGVCRTKSTSDNETSRKNEEVMTHSGLWRTC 67
+++ +T A L AV TD+W V N T H GLWR C
Sbjct: 7 LKVRVTLFCILAGIVLAMTAVVTDHW----AVLSPHMEHHNTTCEA-----AHFGLWRIC 57
Query: 68 -----------CLEGAFRGV--CKKIDHFP--EDADYEQDTA--EYLLRAVRASSVFPIL 110
C G C HF E ++ + T EY + A + I
Sbjct: 58 TKRIPMDDSKTCGPITLPGEKNCSYFRHFNPGESSEIFEFTTQKEYSISA----AAIAIF 113
Query: 111 SVTLLFFGGLCVAASEFHRSRHNVILSAGIFFVSAGLSNIIGIIVYISANAGDPGQRDSK 170
S+ + G LCV S + R ++ A +F+ AGL ++ + V + D+
Sbjct: 114 SLGFIILGSLCVLLS-LGKKRDYLLRPASMFYAFAGLCILVSVEVMRQSVKRMIDSEDTV 172
Query: 171 K-SYSYGWSFYFGAFSFIIAEIVGV 194
Y Y WSF +FI+ + G+
Sbjct: 173 WIEYYYSWSFACACAAFILLFLGGL 197
>gi|4502877 claudin 4 [Homo sapiens]
Length = 209
Score = 37.0 bits (84), Expect = 0.023
Identities = 28/99 (28%), Positives = 42/99 (42%), Gaps = 18/99 (18%)
Query: 62 GLWRTCCLEGAFRGVCKKIDHF---PEDADYEQDTAEYLLRAVRASSVFPI----LSVTL 114
GLW C ++ + CK D P+D L+A RA + I L V L
Sbjct: 49 GLWMNCVVQSTGQMQCKVYDSLLALPQD-----------LQAARALVIISIIVAALGVLL 97
Query: 115 LFFGGLCVAASEFHRSRHNVILSAGIFFVSAGLSNIIGI 153
GG C E ++ ++ AG+ F+ AGL I+ +
Sbjct: 98 SVVGGKCTNCLEDESAKAKTMIVAGVVFLLAGLMVIVPV 136
>gi|153792768 claudin 6 [Homo sapiens]
Length = 220
Score = 35.8 bits (81), Expect = 0.051
Identities = 26/99 (26%), Positives = 44/99 (44%), Gaps = 18/99 (18%)
Query: 62 GLWRTCCLEGAFRGVCKKIDH---FPEDADYEQDTAEYLLRAVRASSVFPIL----SVTL 114
GLW +C ++ + CK D P+D L+A RA V +L + +
Sbjct: 49 GLWMSCVVQSTGQMQCKVYDSLLALPQD-----------LQAARALCVIALLVALFGLLV 97
Query: 115 LFFGGLCVAASEFHRSRHNVILSAGIFFVSAGLSNIIGI 153
G C E S+ ++L++GI FV +G+ +I +
Sbjct: 98 YLAGAKCTTCVEEKDSKARLVLTSGIVFVISGVLTLIPV 136
>gi|239745400 PREDICTED: transmembrane protein 114 [Homo sapiens]
Length = 122
Score = 35.8 bits (81), Expect = 0.051
Identities = 27/93 (29%), Positives = 42/93 (45%), Gaps = 10/93 (10%)
Query: 110 LSVTLLFFGGLCVAASEFHRSRHNVILSAGIFFVSAGLSNIIGIIVYISANAG------- 162
LS+ L+ FGG+ S F + ++L GI F+ + + GI VYI+ +A
Sbjct: 11 LSLILMVFGGMTGFLS-FLLQAYLLLLLTGILFLFGAMVTLAGISVYIAYSAAAFREALC 69
Query: 163 --DPGQRDSKKSYSYGWSFYFGAFSFIIAEIVG 193
+ + S+GWS G SFI + G
Sbjct: 70 LLEEKALLDQVDISFGWSLALGWISFIAELLTG 102
>gi|7705961 claudin 18 isoform 1 [Homo sapiens]
Length = 261
Score = 35.8 bits (81), Expect = 0.051
Identities = 33/135 (24%), Positives = 56/135 (41%), Gaps = 24/135 (17%)
Query: 27 AVGTDYWLYSRGVCRTKSTSDNETSRKNEEVMTHSGLWRTCCLEGAFRGVCKKIDHFPED 86
A G D W T+ DN + V + GLWR+C + + C+
Sbjct: 24 ATGMDMW-------STQDLYDNPVT----SVFQYEGLWRSCVRQSSGFTECRPY------ 66
Query: 87 ADYEQDTAEYLLRAVRASSVFPI----LSVTLLFFGGLCVAASEFHRS-RHNVILSAGIF 141
+ +L+AVRA + I + + + F C+ S + N+ L++GI
Sbjct: 67 --FTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTLTSGIM 124
Query: 142 FVSAGLSNIIGIIVY 156
F+ +GL I G+ V+
Sbjct: 125 FIVSGLCAIAGVSVF 139
>gi|5921465 claudin 10 isoform b [Homo sapiens]
Length = 228
Score = 35.0 bits (79), Expect = 0.087
Identities = 41/190 (21%), Positives = 72/190 (37%), Gaps = 24/190 (12%)
Query: 11 LITTVGAFAAFSLMTIAVGTDYWLYSR--GVCRTKSTSDNETSRKNEEVMTHSGLWRTCC 68
+I + + + + L++ + TDYW S G T +T + LW+ C
Sbjct: 8 IIAFMVSISGWVLVSSTLPTDYWKVSTIDGTVITTATY-------------WANLWKACV 54
Query: 69 LEGAFRGVCKKIDHFPEDADYEQDTAEYLLRAVRASSVFPILSVTLLFFGGLCVAASEFH 128
+ CK Y Q ++ AV I ++ FG C
Sbjct: 55 TDSTGVSNCKDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFAL----FGMKCTKVGGSD 110
Query: 129 RSRHNVILSAGIFFVSAGLSNIIGIIVY---ISANAGDPGQRDSKKSYSYGWSFYFGAFS 185
+++ + AGI F+ +GL ++ G +Y I+ DP + K Y G + + G
Sbjct: 111 KAKAKIACLAGIVFILSGLCSMTGCSLYANKITTEFFDPLFVEQK--YELGAALFIGWAG 168
Query: 186 FIIAEIVGVV 195
+ I GV+
Sbjct: 169 ASLCIIGGVI 178
>gi|50345279 claudin 18 isoform 2 [Homo sapiens]
Length = 261
Score = 35.0 bits (79), Expect = 0.087
Identities = 27/105 (25%), Positives = 47/105 (44%), Gaps = 13/105 (12%)
Query: 57 VMTHSGLWRTCCLEGAFRGVCKKIDHFPEDADYEQDTAEYLLRAVRASSVFPI----LSV 112
V + GLWR+C E + C+ + +L+AVRA + I + +
Sbjct: 43 VFNYQGLWRSCVRESSGFTECRGY--------FTLLGLPAMLQAVRALMIVGIVLGAIGL 94
Query: 113 TLLFFGGLCVAASEFHRS-RHNVILSAGIFFVSAGLSNIIGIIVY 156
+ F C+ S + N+ L++GI F+ +GL I G+ V+
Sbjct: 95 LVSIFALKCIRIGSMEDSAKANMTLTSGIMFIVSGLCAIAGVSVF 139
>gi|123317881 germ cell associated 1 isoform 4 [Homo sapiens]
Length = 362
Score = 34.3 bits (77), Expect = 0.15
Identities = 28/103 (27%), Positives = 46/103 (44%), Gaps = 12/103 (11%)
Query: 143 VSAGLSNIIGIIVYI--------SANAGDPGQRDSKKSYSYGWSFYFGAFSFIIAEIVGV 194
VS+ LS ++G++ ++ + N G R ++YGW+FY SF V
Sbjct: 206 VSSVLSGLLGMVAHMMYSQVFQATVNLGPEDWRPHV--WNYGWAFYMAWLSFTCCMASAV 263
Query: 195 VAVHIYIEKHQQLRAKSHSEFLKKSTFARLPPYRYRFRRRSSS 237
+ Y + + K HS+ K++ LP + F RR SS
Sbjct: 264 TTFNTYTRMVLEFKCK-HSKSFKENPNC-LPHHHQCFPRRLSS 304
>gi|123317861 germ cell associated 1 isoform 2 [Homo sapiens]
Length = 326
Score = 34.3 bits (77), Expect = 0.15
Identities = 28/103 (27%), Positives = 46/103 (44%), Gaps = 12/103 (11%)
Query: 143 VSAGLSNIIGIIVYI--------SANAGDPGQRDSKKSYSYGWSFYFGAFSFIIAEIVGV 194
VS+ LS ++G++ ++ + N G R ++YGW+FY SF V
Sbjct: 170 VSSVLSGLLGMVAHMMYSQVFQATVNLGPEDWRPHV--WNYGWAFYMAWLSFTCCMASAV 227
Query: 195 VAVHIYIEKHQQLRAKSHSEFLKKSTFARLPPYRYRFRRRSSS 237
+ Y + + K HS+ K++ LP + F RR SS
Sbjct: 228 TTFNTYTRMVLEFKCK-HSKSFKENPNC-LPHHHQCFPRRLSS 268
>gi|11141861 claudin 9 [Homo sapiens]
Length = 217
Score = 33.9 bits (76), Expect = 0.19
Identities = 25/99 (25%), Positives = 42/99 (42%), Gaps = 18/99 (18%)
Query: 62 GLWRTCCLEGAFRGVCKKIDHF---PEDADYEQDTAEYLLRAVRASSVFPILSVTL---- 114
GLW +C ++ + CK D P+D L+A RA V +L L
Sbjct: 49 GLWMSCVVQSTGQMQCKVYDSLLALPQD-----------LQAARALCVIALLLALLGLLV 97
Query: 115 LFFGGLCVAASEFHRSRHNVILSAGIFFVSAGLSNIIGI 153
G C E ++ ++L+AG+ + AG+ +I +
Sbjct: 98 AITGAQCTTCVEDEGAKARIVLTAGVILLLAGILVLIPV 136
>gi|4503559 epithelial membrane protein 1 [Homo sapiens]
Length = 157
Score = 33.1 bits (74), Expect = 0.33
Identities = 23/96 (23%), Positives = 40/96 (41%), Gaps = 5/96 (5%)
Query: 100 AVRASSVFPILSVTLLFFGGLCVAASEFHRSRHNVILSAGIFFVSAGLSNIIGIIVYISA 159
A++ F ILS+ L F + N +G + L ++G+ +Y S
Sbjct: 60 ALKTVQAFMILSIIFCVIALLVFVFQLFTMEKGNRFFLSGATTLVCWLCILVGVSIYTSH 119
Query: 160 NAGDPGQRDSKKSYSYGWSFYFGAFSFIIAEIVGVV 195
A G + Y +G+S+ G F + I+GV+
Sbjct: 120 YANRDGTQ-----YHHGYSYILGWICFCFSFIIGVL 150
>gi|47716519 claudin 20 [Homo sapiens]
Length = 219
Score = 33.1 bits (74), Expect = 0.33
Identities = 26/106 (24%), Positives = 48/106 (45%), Gaps = 4/106 (3%)
Query: 106 VFPILSVTLLFFGGLCVAASEFHRSRHNVILSAGIFFVSAGLSNIIGIIVY---ISANAG 162
V L + G C ++ + + G+ F+SAG+S++I + Y I AN
Sbjct: 89 VLSALGICTSTVGMKCTRLGGDRETKSHASFAGGVCFMSAGISSLISTVWYTKEIIANFL 148
Query: 163 DPGQRDSKKSYSYGWSFYFGAFSFIIAEIVGVVAVHIYIEKHQQLR 208
D +S K + G + Y G S ++ I G++ I+++ + R
Sbjct: 149 DLTVPESNK-HEPGGAIYIGFISAMLLFISGMIFCTSCIKRNPEAR 193
>gi|21361300 lens intrinsic membrane protein 2, 19kDa isoform 1
[Homo sapiens]
Length = 215
Score = 32.3 bits (72), Expect = 0.56
Identities = 25/101 (24%), Positives = 43/101 (42%), Gaps = 5/101 (4%)
Query: 103 ASSVFPILSVTLLFFG---GLCVAASEFHRSRHNVILSAGIFFVSAGLSNIIGIIVYISA 159
A+ F ILS G G+ A + SR + SAGI F S+ L ++ + +Y
Sbjct: 105 ATRAFMILSALCAISGIIMGIMAFAHQPTFSRISRPFSAGIMFFSSTLFVVLALAIYTGV 164
Query: 160 NAGDPGQRDSKKSYSYGWSFYFGAFSFIIAEIVGVVAVHIY 200
G+R + + WS+ G + ++ G+ + Y
Sbjct: 165 TVSFLGRRFG--DWRFSWSYILGWVAVLMTFFAGIFYMCAY 203
>gi|33598916 claudin 10 isoform a [Homo sapiens]
Length = 226
Score = 32.3 bits (72), Expect = 0.56
Identities = 37/163 (22%), Positives = 62/163 (38%), Gaps = 12/163 (7%)
Query: 39 VCRTKSTSDNETSRKNEEVMT---HSGLWRTCCLEGAFRGVCKKIDHFPEDADYEQDTAE 95
V T S T+R + + + GLW C C+ + A Y Q
Sbjct: 20 VAATTSNEWKVTTRASSVITATWVYQGLWMNCAGNALGSFHCRPHFTIFKVAGYIQACRG 79
Query: 96 YLLRAVRASSVFPILSVTLLFFGGLCVAASEFHRSRHNVILSAGIFFVSAGLSNIIGIIV 155
++ AV I ++ FG C +++ + AGI F+ +GL ++ G +
Sbjct: 80 LMIAAVSLGFFGSIFAL----FGMKCTKVGGSDKAKAKIACLAGIVFILSGLCSMTGCSL 135
Query: 156 Y---ISANAGDPGQRDSKKSYSYGWSFYFGAFSFIIAEIVGVV 195
Y I+ DP + K Y G + + G + I GV+
Sbjct: 136 YANKITTEFFDPLFVEQK--YELGAALFIGWAGASLCIIGGVI 176
>gi|9558733 transformer-2 alpha [Homo sapiens]
Length = 282
Score = 32.0 bits (71), Expect = 0.73
Identities = 29/81 (35%), Positives = 40/81 (49%), Gaps = 14/81 (17%)
Query: 202 EKHQQLRAKSHSEFLKKS--TFARLPPYRYRFRRRSSSRSTEP-----RSRDLSPIS-KG 253
E H + R+KS S + S + R + + RRRS SRS P RSR SP+S +
Sbjct: 47 ESHSRSRSKSRSRSRRHSHRRYTRSRSHSHSHRRRSRSRSYTPEYRRRRSRSHSPMSNRR 106
Query: 254 FHT------IPSTDISMFTLS 268
HT P+T + +F LS
Sbjct: 107 RHTGSRANPDPNTCLGVFGLS 127
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.135 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,222,628
Number of Sequences: 37866
Number of extensions: 456352
Number of successful extensions: 1128
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 36
Number of HSP's that attempted gapping in prelim test: 1069
Number of HSP's gapped (non-prelim): 57
length of query: 315
length of database: 18,247,518
effective HSP length: 102
effective length of query: 213
effective length of database: 14,385,186
effective search space: 3064044618
effective search space used: 3064044618
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.