Guide to the Human Genome
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Search of human proteins with 57242782

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|57242782 MAX interactor 1 isoform a [Homo sapiens]
         (228 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|57242782 MAX interactor 1 isoform a [Homo sapiens]                 450   e-127
gi|47717116 MAX interactor 1 isoform b [Homo sapiens]                 420   e-118
gi|57242784 MAX interactor 1 isoform c [Homo sapiens]                 351   3e-97
gi|4505069 MAX dimerization protein 1 [Homo sapiens]                  242   2e-64
gi|5453734 MAD4 [Homo sapiens]                                        184   7e-47
gi|13775222 MAX dimerization protein 3 isoform a [Homo sapiens]       165   3e-41
gi|219283190 MAX dimerization protein 3 isoform b [Homo sapiens]      148   3e-36
gi|9945318 MAX binding protein [Homo sapiens]                          65   5e-11
gi|71774083 myc proto-oncogene protein [Homo sapiens]                  49   3e-06
gi|6005934 upstream stimulatory factor 1 isoform 1 [Homo sapiens]      43   2e-04
gi|46877102 upstream stimulatory factor 1 isoform 2 [Homo sapiens]     43   2e-04
gi|74315997 l-myc-1 proto-oncogene isoform 1 [Homo sapiens]            42   6e-04
gi|74315995 l-myc-1 proto-oncogene isoform 1 [Homo sapiens]            42   6e-04
gi|8659574 transcription factor E3 [Homo sapiens]                      42   6e-04
gi|46877105 upstream stimulatory factor 2 isoform 2 [Homo sapiens]     42   6e-04
gi|4507847 upstream stimulatory factor 2 isoform 1 [Homo sapiens]      42   6e-04
gi|64762402 transcription factor EC isoform b [Homo sapiens]           41   0.001
gi|6912702 transcription factor EC isoform a [Homo sapiens]            41   0.001
gi|40068059 CBF1 interacting corepressor [Homo sapiens]                39   0.005
gi|151301228 formin binding protein 3 [Homo sapiens]                   38   0.006
gi|38156705 microphthalmia-associated transcription factor isofo...    38   0.008
gi|38156703 microphthalmia-associated transcription factor isofo...    38   0.008
gi|38156701 microphthalmia-associated transcription factor isofo...    38   0.008
gi|38156699 microphthalmia-associated transcription factor isofo...    38   0.008
gi|38156697 microphthalmia-associated transcription factor isofo...    38   0.008
gi|21704263 MAX protein isoform b [Homo sapiens]                       38   0.008
gi|21704261 MAX protein isoform a [Homo sapiens]                       38   0.008
gi|13540521 basic helix-loop-helix domain containing, class B, 3...    38   0.008
gi|4557755 microphthalmia-associated transcription factor isofor...    37   0.014
gi|58530842 desmoplakin isoform II [Homo sapiens]                      37   0.018

>gi|57242782 MAX interactor 1 isoform a [Homo sapiens]
          Length = 228

 Score =  450 bits (1158), Expect = e-127
 Identities = 228/228 (100%), Positives = 228/228 (100%)

Query: 1   MERVKMINVQRLLEAAEFLERRERECEHGYASSFPSMPSPRLQHSKPPRRLSRAQKHSSG 60
           MERVKMINVQRLLEAAEFLERRERECEHGYASSFPSMPSPRLQHSKPPRRLSRAQKHSSG
Sbjct: 1   MERVKMINVQRLLEAAEFLERRERECEHGYASSFPSMPSPRLQHSKPPRRLSRAQKHSSG 60

Query: 61  SSNTSTANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLE 120
           SSNTSTANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLE
Sbjct: 61  SSNTSTANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLE 120

Query: 121 EAERKSQHQLENLEREQRFLKWRLEQLQGPQEMERIRMDSIGSTISSDRSDSEREEIEVD 180
           EAERKSQHQLENLEREQRFLKWRLEQLQGPQEMERIRMDSIGSTISSDRSDSEREEIEVD
Sbjct: 121 EAERKSQHQLENLEREQRFLKWRLEQLQGPQEMERIRMDSIGSTISSDRSDSEREEIEVD 180

Query: 181 VESTEFSHGEVDNISTTSISDIDDHSSLPSIGSDEGYSSASVKLSFTS 228
           VESTEFSHGEVDNISTTSISDIDDHSSLPSIGSDEGYSSASVKLSFTS
Sbjct: 181 VESTEFSHGEVDNISTTSISDIDDHSSLPSIGSDEGYSSASVKLSFTS 228


>gi|47717116 MAX interactor 1 isoform b [Homo sapiens]
          Length = 295

 Score =  420 bits (1080), Expect = e-118
 Identities = 215/224 (95%), Positives = 218/224 (97%), Gaps = 3/224 (1%)

Query: 8   NVQRLLEAAEFLERRERE---CEHGYASSFPSMPSPRLQHSKPPRRLSRAQKHSSGSSNT 64
           NVQ LLEAA +LE+ E+E   CEHGYASSFPSMPSPRLQHSKPPRRLSRAQKHSSGSSNT
Sbjct: 72  NVQILLEAASYLEQIEKENKKCEHGYASSFPSMPSPRLQHSKPPRRLSRAQKHSSGSSNT 131

Query: 65  STANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAER 124
           STANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAER
Sbjct: 132 STANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAER 191

Query: 125 KSQHQLENLEREQRFLKWRLEQLQGPQEMERIRMDSIGSTISSDRSDSEREEIEVDVEST 184
           KSQHQLENLEREQRFLKWRLEQLQGPQEMERIRMDSIGSTISSDRSDSEREEIEVDVEST
Sbjct: 192 KSQHQLENLEREQRFLKWRLEQLQGPQEMERIRMDSIGSTISSDRSDSEREEIEVDVEST 251

Query: 185 EFSHGEVDNISTTSISDIDDHSSLPSIGSDEGYSSASVKLSFTS 228
           EFSHGEVDNISTTSISDIDDHSSLPSIGSDEGYSSASVKLSFTS
Sbjct: 252 EFSHGEVDNISTTSISDIDDHSSLPSIGSDEGYSSASVKLSFTS 295


>gi|57242784 MAX interactor 1 isoform c [Homo sapiens]
          Length = 182

 Score =  351 bits (901), Expect = 3e-97
 Identities = 182/192 (94%), Positives = 182/192 (94%), Gaps = 10/192 (5%)

Query: 37  MPSPRLQHSKPPRRLSRAQKHSSGSSNTSTANRSTHNELEKNRRAHLRLCLERLKVLIPL 96
           MPSPRLQHSKPPRRLSRAQKHSSGSSNTSTANR          RAHLRLCLERLKVLIPL
Sbjct: 1   MPSPRLQHSKPPRRLSRAQKHSSGSSNTSTANR----------RAHLRLCLERLKVLIPL 50

Query: 97  GPDCTRHTTLGLLNKAKAHIKKLEEAERKSQHQLENLEREQRFLKWRLEQLQGPQEMERI 156
           GPDCTRHTTLGLLNKAKAHIKKLEEAERKSQHQLENLEREQRFLKWRLEQLQGPQEMERI
Sbjct: 51  GPDCTRHTTLGLLNKAKAHIKKLEEAERKSQHQLENLEREQRFLKWRLEQLQGPQEMERI 110

Query: 157 RMDSIGSTISSDRSDSEREEIEVDVESTEFSHGEVDNISTTSISDIDDHSSLPSIGSDEG 216
           RMDSIGSTISSDRSDSEREEIEVDVESTEFSHGEVDNISTTSISDIDDHSSLPSIGSDEG
Sbjct: 111 RMDSIGSTISSDRSDSEREEIEVDVESTEFSHGEVDNISTTSISDIDDHSSLPSIGSDEG 170

Query: 217 YSSASVKLSFTS 228
           YSSASVKLSFTS
Sbjct: 171 YSSASVKLSFTS 182


>gi|4505069 MAX dimerization protein 1 [Homo sapiens]
          Length = 221

 Score =  242 bits (617), Expect = 2e-64
 Identities = 128/217 (58%), Positives = 167/217 (76%), Gaps = 16/217 (7%)

Query: 7   INVQRLLEAAEFLERRERECEHGYASSFPSMPSPRLQHSKPPRRLSRAQKHSSGSSNTST 66
           +N+Q LLEAA++LERRERE EHGYAS  P        ++K    L R  K    S   ++
Sbjct: 7   MNIQMLLEAADYLERREREAEHGYASMLP-------YNNKDRDALKRRNK----SKKNNS 55

Query: 67  ANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAERKS 126
           ++RSTHNE+EKNRRAHLRLCLE+LK L+PLGP+ +RHTTL LL KAK HIKKLE+ +RK+
Sbjct: 56  SSRSTHNEMEKNRRAHLRLCLEKLKGLVPLGPESSRHTTLSLLTKAKLHIKKLEDCDRKA 115

Query: 127 QHQLENLEREQRFLKWRLEQLQGPQEMERIRMDSIGSTISSDRSDSEREEIEVDVESTEF 186
            HQ++ L+REQR LK +LE+L     +ERIRMDSIGST+SS+RSDS+REEI+VDVEST++
Sbjct: 116 VHQIDQLQREQRHLKRQLEKL----GIERIRMDSIGSTVSSERSDSDREEIDVDVESTDY 171

Query: 187 SHGEVDNISTTSISDIDDHSSLPSIGSDEGYSSASVK 223
             G++D  S++S+SD D+  S+ S+GSDEGYSS S+K
Sbjct: 172 LTGDLD-WSSSSVSDSDERGSMQSLGSDEGYSSTSIK 207


>gi|5453734 MAD4 [Homo sapiens]
          Length = 209

 Score =  184 bits (466), Expect = 7e-47
 Identities = 110/207 (53%), Positives = 137/207 (66%), Gaps = 20/207 (9%)

Query: 12  LLEAAEFLERRERECEHGYASSFPSMPSPRLQHSKPPRRLSRAQKHSSGSSNTSTANRST 71
           LLEAAE+LERR+RE EHGYAS  P                +R +  ++G    +  NRS+
Sbjct: 9   LLEAAEYLERRDREAEHGYASVLPFDGD-----------FAREKTKAAGLVRKAPNNRSS 57

Query: 72  HNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAERKSQHQLE 131
           HNELEK+RRA LRL LE+LK L+PLGPD TRHTTL LL +AK HIKKLEE +R++    E
Sbjct: 58  HNELEKHRRAKLRLYLEQLKQLVPLGPDSTRHTTLSLLKRAKVHIKKLEEQDRRALSIKE 117

Query: 132 NLEREQRFLKWRLEQLQGPQEMERIRMDSIGSTISSDRSDSEREEIEVDVESTEFSHGEV 191
            L++E RFLK RLEQL   Q +ER+R DS GS +S+D  DSE+   EVD+E  EF  GE+
Sbjct: 118 QLQQEHRFLKRRLEQL-SVQSVERVRTDSTGSAVSTD--DSEQ---EVDIEGMEFGPGEL 171

Query: 192 DNISTTSISDIDDHSSLPS-IGSDEGY 217
           D++   S SD DDH SL S  G D G+
Sbjct: 172 DSVG--SSSDADDHYSLQSGTGGDSGF 196


>gi|13775222 MAX dimerization protein 3 isoform a [Homo sapiens]
          Length = 206

 Score =  165 bits (418), Expect = 3e-41
 Identities = 94/189 (49%), Positives = 126/189 (66%), Gaps = 14/189 (7%)

Query: 8   NVQRLLEAAEFLERRERECEHGYASSFPSMPSPRLQHSKPPRRLSRAQKHSSGSSNTSTA 67
           N+Q LL+AAEFLERRERE EHGYAS  P          + P  + R +K    +     +
Sbjct: 7   NIQVLLQAAEFLERREREAEHGYASLCPH---------RSPGPIHRRKKRPPQAPGAQDS 57

Query: 68  NRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAERKSQ 127
            RS HNELEK RRA L+ CLERLK  +PLG DC R+TTL LL +A+ HI+KLE+ E++++
Sbjct: 58  GRSVHNELEKRRRAQLKRCLERLKQQMPLGADCARYTTLSLLRRARMHIQKLEDQEQRAR 117

Query: 128 HQLENLEREQRFLKWRLEQLQ---GPQEMERIRMDSIGST-ISSDRSDSEREEIEVDVES 183
              E L  +Q+ L+ +LEQL+   G  E ER+R DS+ S+ +SS+RSDS++EE+EVDVES
Sbjct: 118 QLKERLRSKQQSLQRQLEQLRGLAGAAERERLRADSLDSSGLSSERSDSDQEELEVDVES 177

Query: 184 TEFSHGEVD 192
             F  GE +
Sbjct: 178 LVFG-GEAE 185


>gi|219283190 MAX dimerization protein 3 isoform b [Homo sapiens]
          Length = 193

 Score =  148 bits (374), Expect = 3e-36
 Identities = 83/171 (48%), Positives = 113/171 (66%), Gaps = 13/171 (7%)

Query: 8   NVQRLLEAAEFLERRERECEHGYASSFPSMPSPRLQHSKPPRRLSRAQKHSSGSSNTSTA 67
           N+Q LL+AAEFLERRERE EHGYAS  P          + P  + R +K    +     +
Sbjct: 7   NIQVLLQAAEFLERREREAEHGYASLCPH---------RSPGPIHRRKKRPPQAPGAQDS 57

Query: 68  NRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAERKSQ 127
            RS HNELEK RRA L+ CLERLK  +PLG DC R+TTL LL +A+ HI+KLE+ E++++
Sbjct: 58  GRSVHNELEKRRRAQLKRCLERLKQQMPLGADCARYTTLSLLRRARMHIQKLEDQEQRAR 117

Query: 128 HQLENLEREQRFLKWRLEQLQ---GPQEMERIRMDSIGST-ISSDRSDSER 174
              E L  +Q+ L+ +LEQL+   G  E ER+R DS+ S+ +SS+RSDS++
Sbjct: 118 QLKERLRSKQQSLQRQLEQLRGLAGAAERERLRADSLDSSGLSSERSDSDQ 168


>gi|9945318 MAX binding protein [Homo sapiens]
          Length = 582

 Score = 65.1 bits (157), Expect = 5e-11
 Identities = 49/143 (34%), Positives = 72/143 (50%), Gaps = 19/143 (13%)

Query: 52  SRAQKHSSGSSNTSTANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNK 111
           S  QK   G   T    R  HN+LEKNRRAHL+ C E LK  IP   D  + + L +L  
Sbjct: 209 SSEQKKRPGGIGT----REVHNKLEKNRRAHLKECFETLKRNIP-NVDDKKTSNLSVLRT 263

Query: 112 AKAHIKKLEEAERKSQHQLENLERE-----QRF--LKWRLEQLQGPQEMERI-------R 157
           A  +I+ L+  E++ +H++E L RE     QR   LK  L Q     E++R+        
Sbjct: 264 ALRYIQSLKRKEKEYEHEMERLAREKIATQQRLAELKHELSQWMDVLEIDRVLRQTGQPE 323

Query: 158 MDSIGSTISSDRSDSEREEIEVD 180
            D   ++ +S+  D+  E++E D
Sbjct: 324 DDQASTSTASEGEDNIDEDMEED 346


>gi|71774083 myc proto-oncogene protein [Homo sapiens]
          Length = 454

 Score = 49.3 bits (116), Expect = 3e-06
 Identities = 37/130 (28%), Positives = 66/130 (50%), Gaps = 8/130 (6%)

Query: 27  EHGYAS------SFPSMPSPRLQHSKPPRRLSRAQKHSSGSSNTSTAN--RSTHNELEKN 78
           +H YA+       +P+    +L   +  R++S  +K +S  S+ +  N  R THN LE+ 
Sbjct: 321 QHNYAAPPSTRKDYPAAKRVKLDSVRVLRQISNNRKCTSPRSSDTEENVKRRTHNVLERQ 380

Query: 79  RRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAERKSQHQLENLEREQR 138
           RR  L+     L+  IP   +  +   + +L KA A+I  ++  E+K   + + L + + 
Sbjct: 381 RRNELKRSFFALRDQIPELENNEKAPKVVILKKATAYILSVQAEEQKLISEEDLLRKRRE 440

Query: 139 FLKWRLEQLQ 148
            LK +LEQL+
Sbjct: 441 QLKHKLEQLR 450


>gi|6005934 upstream stimulatory factor 1 isoform 1 [Homo sapiens]
          Length = 310

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 30/125 (24%), Positives = 62/125 (49%), Gaps = 12/125 (9%)

Query: 43  QHSKPPRRLSRAQKHSSGSSNTSTANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTR 102
           Q S  PR    + K  +  +      R+ HNE+E+ RR  +   + +L  +I   PDC+ 
Sbjct: 175 QRSIAPRTHPYSPKSEAPRTTRDEKRRAQHNEVERRRRDKINNWIVQLSKII---PDCSM 231

Query: 103 HTTL------GLLNKAKAHIKKLEEAERKSQHQLENLER---EQRFLKWRLEQLQGPQEM 153
            +T       G+L+KA  +I++L ++  +   +L+ L++   +   L+ ++E L+    +
Sbjct: 232 ESTKSGQSKGGILSKACDYIQELRQSNHRLSEELQGLDQLQLDNDVLRQQVEDLKNKNLL 291

Query: 154 ERIRM 158
            R ++
Sbjct: 292 LRAQL 296


>gi|46877102 upstream stimulatory factor 1 isoform 2 [Homo sapiens]
          Length = 251

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 30/125 (24%), Positives = 62/125 (49%), Gaps = 12/125 (9%)

Query: 43  QHSKPPRRLSRAQKHSSGSSNTSTANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTR 102
           Q S  PR    + K  +  +      R+ HNE+E+ RR  +   + +L  +I   PDC+ 
Sbjct: 116 QRSIAPRTHPYSPKSEAPRTTRDEKRRAQHNEVERRRRDKINNWIVQLSKII---PDCSM 172

Query: 103 HTTL------GLLNKAKAHIKKLEEAERKSQHQLENLER---EQRFLKWRLEQLQGPQEM 153
            +T       G+L+KA  +I++L ++  +   +L+ L++   +   L+ ++E L+    +
Sbjct: 173 ESTKSGQSKGGILSKACDYIQELRQSNHRLSEELQGLDQLQLDNDVLRQQVEDLKNKNLL 232

Query: 154 ERIRM 158
            R ++
Sbjct: 233 LRAQL 237


>gi|74315997 l-myc-1 proto-oncogene isoform 1 [Homo sapiens]
          Length = 364

 Score = 41.6 bits (96), Expect = 6e-04
 Identities = 30/108 (27%), Positives = 47/108 (43%), Gaps = 3/108 (2%)

Query: 45  SKPPRRLSRAQK---HSSGSSNTSTANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCT 101
           S PP     AQ        S       R  HN LE+ RR  LR     L+  +P    C+
Sbjct: 256 SPPPVESEAAQSCHPKPVSSDTEDVTKRKNHNFLERKRRNDLRSRFLALRDQVPTLASCS 315

Query: 102 RHTTLGLLNKAKAHIKKLEEAERKSQHQLENLEREQRFLKWRLEQLQG 149
           +   + +L+KA  +++ L  AE++   +   L   Q+ L+ R+  L G
Sbjct: 316 KAPKVVILSKALEYLQALVGAEKRMATEKRQLRCRQQQLQKRIAYLTG 363


>gi|74315995 l-myc-1 proto-oncogene isoform 1 [Homo sapiens]
          Length = 364

 Score = 41.6 bits (96), Expect = 6e-04
 Identities = 30/108 (27%), Positives = 47/108 (43%), Gaps = 3/108 (2%)

Query: 45  SKPPRRLSRAQK---HSSGSSNTSTANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCT 101
           S PP     AQ        S       R  HN LE+ RR  LR     L+  +P    C+
Sbjct: 256 SPPPVESEAAQSCHPKPVSSDTEDVTKRKNHNFLERKRRNDLRSRFLALRDQVPTLASCS 315

Query: 102 RHTTLGLLNKAKAHIKKLEEAERKSQHQLENLEREQRFLKWRLEQLQG 149
           +   + +L+KA  +++ L  AE++   +   L   Q+ L+ R+  L G
Sbjct: 316 KAPKVVILSKALEYLQALVGAEKRMATEKRQLRCRQQQLQKRIAYLTG 363


>gi|8659574 transcription factor E3 [Homo sapiens]
          Length = 575

 Score = 41.6 bits (96), Expect = 6e-04
 Identities = 30/120 (25%), Positives = 63/120 (52%), Gaps = 10/120 (8%)

Query: 69  RSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKA-HIKKLEEAERKS- 126
           +  HN +E+ RR ++   ++ L  LIP   D       G + KA   +I+KL++ +++S 
Sbjct: 348 KDNHNLIERRRRFNINDRIKELGTLIPKSSDPEMRWNKGTILKASVDYIRKLQKEQQRSK 407

Query: 127 --QHQLENLEREQRFLKWRLEQLQGPQEMERIRMD------SIGSTISSDRSDSEREEIE 178
             + +  +LE+  R L+ R+++L+   ++  + +       S+ +T +SD    E+ +IE
Sbjct: 408 DLESRQRSLEQANRSLQLRIQELELQAQIHGLPVPPTPGLLSLATTSASDSLKPEQLDIE 467


>gi|46877105 upstream stimulatory factor 2 isoform 2 [Homo sapiens]
          Length = 279

 Score = 41.6 bits (96), Expect = 6e-04
 Identities = 30/125 (24%), Positives = 60/125 (48%), Gaps = 12/125 (9%)

Query: 43  QHSKPPRRLSRAQKHSSGSSNTSTANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDC-- 100
           Q +  PR    + K     +      R+ HNE+E+ RR  +   + +L  +I   PDC  
Sbjct: 144 QRTIAPRTHPYSPKIDGTRTPRDERRRAQHNEVERRRRDKINNWIVQLSKII---PDCNA 200

Query: 101 ----TRHTTLGLLNKAKAHIKKLEEAERKSQH---QLENLEREQRFLKWRLEQLQGPQEM 153
               T  +  G+L+KA  +I++L +  ++ Q    + E L+ +   L+ ++E+L+    +
Sbjct: 201 DNSKTGASKGGILSKACDYIRELRQTNQRMQETFKEAERLQMDNELLRQQIEELKNENAL 260

Query: 154 ERIRM 158
            R ++
Sbjct: 261 LRAQL 265


>gi|4507847 upstream stimulatory factor 2 isoform 1 [Homo sapiens]
          Length = 346

 Score = 41.6 bits (96), Expect = 6e-04
 Identities = 30/125 (24%), Positives = 60/125 (48%), Gaps = 12/125 (9%)

Query: 43  QHSKPPRRLSRAQKHSSGSSNTSTANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDC-- 100
           Q +  PR    + K     +      R+ HNE+E+ RR  +   + +L  +I   PDC  
Sbjct: 211 QRTIAPRTHPYSPKIDGTRTPRDERRRAQHNEVERRRRDKINNWIVQLSKII---PDCNA 267

Query: 101 ----TRHTTLGLLNKAKAHIKKLEEAERKSQH---QLENLEREQRFLKWRLEQLQGPQEM 153
               T  +  G+L+KA  +I++L +  ++ Q    + E L+ +   L+ ++E+L+    +
Sbjct: 268 DNSKTGASKGGILSKACDYIRELRQTNQRMQETFKEAERLQMDNELLRQQIEELKNENAL 327

Query: 154 ERIRM 158
            R ++
Sbjct: 328 LRAQL 332


>gi|64762402 transcription factor EC isoform b [Homo sapiens]
          Length = 318

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 26/120 (21%), Positives = 57/120 (47%), Gaps = 10/120 (8%)

Query: 69  RSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAH----IKKLEEAER 124
           +  HN +E+ RR ++   ++ L  LIP   D       G + KA       ++K ++  R
Sbjct: 112 KDNHNLIERRRRYNINYRIKELGTLIPKSNDPDMRWNKGTILKASVEYIKWLQKEQQRAR 171

Query: 125 KSQHQLENLEREQRFLKWRLEQLQ------GPQEMERIRMDSIGSTISSDRSDSEREEIE 178
           + +H+ + LE+  R L  R+++L+      G   +  +    +G+ ++  +S  E+  ++
Sbjct: 172 ELEHRQKKLEQANRRLLLRIQELEIQARTHGLPTLASLGTVDLGAHVTKQQSHPEQNSVD 231


>gi|6912702 transcription factor EC isoform a [Homo sapiens]
          Length = 347

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 26/120 (21%), Positives = 57/120 (47%), Gaps = 10/120 (8%)

Query: 69  RSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAH----IKKLEEAER 124
           +  HN +E+ RR ++   ++ L  LIP   D       G + KA       ++K ++  R
Sbjct: 141 KDNHNLIERRRRYNINYRIKELGTLIPKSNDPDMRWNKGTILKASVEYIKWLQKEQQRAR 200

Query: 125 KSQHQLENLEREQRFLKWRLEQLQ------GPQEMERIRMDSIGSTISSDRSDSEREEIE 178
           + +H+ + LE+  R L  R+++L+      G   +  +    +G+ ++  +S  E+  ++
Sbjct: 201 ELEHRQKKLEQANRRLLLRIQELEIQARTHGLPTLASLGTVDLGAHVTKQQSHPEQNSVD 260


>gi|40068059 CBF1 interacting corepressor [Homo sapiens]
          Length = 450

 Score = 38.5 bits (88), Expect = 0.005
 Identities = 34/132 (25%), Positives = 55/132 (41%), Gaps = 13/132 (9%)

Query: 10  QRLLEAAEFLERRERECEHGYASSFPSMPSPRLQHSKPPRRLSRAQKHSSGSSNTSTANR 69
           Q+LL   + LE+++++ +        S        SK  +  S +   SS SS++ST   
Sbjct: 222 QKLLRKLDRLEKKKKKKDRKKKKFQKS-------RSKHKKHKSSSSSSSSSSSSSSTETS 274

Query: 70  STHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAERKSQHQ 129
            + +E E N +       +R K        C+ H       K K+  +KL E    S H 
Sbjct: 275 ESSSESESNNKEKKIQRKKRKK------NKCSGHNNSDSEEKDKSKKRKLHEELSSSHHN 328

Query: 130 LENLEREQRFLK 141
            E  + + RFLK
Sbjct: 329 REKAKEKPRFLK 340


>gi|151301228 formin binding protein 3 [Homo sapiens]
          Length = 930

 Score = 38.1 bits (87), Expect = 0.006
 Identities = 42/188 (22%), Positives = 77/188 (40%), Gaps = 27/188 (14%)

Query: 17  EFLERRERECEHGYASSFPSMPSPRLQHSKPPRRLSRAQKHSSGSSNTSTANRSTHNELE 76
           +F+   E EC+H +        S   +HSK  ++  R  K S   S + + +  +H++ +
Sbjct: 768 DFMHVLEHECQHHH--------SKNKKHSKKSKKHHR--KRSRSRSGSDSDDDDSHSK-K 816

Query: 77  KNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAERKSQHQLENLERE 136
           K +R+  R   E            +   +     K+K H KK ++   KS     + ERE
Sbjct: 817 KRQRSESRSASEH----------SSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAERE 866

Query: 137 QRFLKWRLEQLQGPQEMERIRMDSIGSTISSDRSDSEREEIEVDVESTEFSHGEVDNIST 196
           +       ++     E +R R  S  S   S +  + ++    D   +E S GE++    
Sbjct: 867 K-----DKKEKDRESEKDRTRQRS-ESKHKSPKKKTGKDSGNWDTSGSELSEGELEKRRR 920

Query: 197 TSISDIDD 204
           T +  +DD
Sbjct: 921 TLLEQLDD 928


>gi|38156705 microphthalmia-associated transcription factor isoform
           6 [Homo sapiens]
          Length = 495

 Score = 37.7 bits (86), Expect = 0.008
 Identities = 33/122 (27%), Positives = 59/122 (48%), Gaps = 11/122 (9%)

Query: 37  MPSPRLQHSKP-PRRLSRAQKHSSGSSNTSTAN----RSTHNELEKNRRAHLRLCLERLK 91
           +P P L  S   P  L   ++  + S   + A     +  HN +E+ RR ++   ++ L 
Sbjct: 245 LPPPGLTISNSCPANLPNIKRELTESEARALAKERQKKDNHNLIERRRRFNINDRIKELG 304

Query: 92  VLIPLGPDCTRHTTLGLLNKAKA-HIKKLEEAERKSQHQLEN----LEREQRFLKWRLEQ 146
            LIP   D       G + KA   +I+KL+  +++++ +LEN    LE   R L  R+++
Sbjct: 305 TLIPKSNDPDMRWNKGTILKASVDYIRKLQREQQRAK-ELENRQKKLEHANRHLLLRIQE 363

Query: 147 LQ 148
           L+
Sbjct: 364 LE 365


>gi|38156703 microphthalmia-associated transcription factor isoform
           2 [Homo sapiens]
          Length = 504

 Score = 37.7 bits (86), Expect = 0.008
 Identities = 33/122 (27%), Positives = 59/122 (48%), Gaps = 11/122 (9%)

Query: 37  MPSPRLQHSKP-PRRLSRAQKHSSGSSNTSTAN----RSTHNELEKNRRAHLRLCLERLK 91
           +P P L  S   P  L   ++  + S   + A     +  HN +E+ RR ++   ++ L 
Sbjct: 254 LPPPGLTISNSCPANLPNIKRELTESEARALAKERQKKDNHNLIERRRRFNINDRIKELG 313

Query: 92  VLIPLGPDCTRHTTLGLLNKAKA-HIKKLEEAERKSQHQLEN----LEREQRFLKWRLEQ 146
            LIP   D       G + KA   +I+KL+  +++++ +LEN    LE   R L  R+++
Sbjct: 314 TLIPKSNDPDMRWNKGTILKASVDYIRKLQREQQRAK-ELENRQKKLEHANRHLLLRIQE 372

Query: 147 LQ 148
           L+
Sbjct: 373 LE 374


>gi|38156701 microphthalmia-associated transcription factor isoform
           3 [Homo sapiens]
          Length = 519

 Score = 37.7 bits (86), Expect = 0.008
 Identities = 33/122 (27%), Positives = 59/122 (48%), Gaps = 11/122 (9%)

Query: 37  MPSPRLQHSKP-PRRLSRAQKHSSGSSNTSTAN----RSTHNELEKNRRAHLRLCLERLK 91
           +P P L  S   P  L   ++  + S   + A     +  HN +E+ RR ++   ++ L 
Sbjct: 269 LPPPGLTISNSCPANLPNIKRELTESEARALAKERQKKDNHNLIERRRRFNINDRIKELG 328

Query: 92  VLIPLGPDCTRHTTLGLLNKAKA-HIKKLEEAERKSQHQLEN----LEREQRFLKWRLEQ 146
            LIP   D       G + KA   +I+KL+  +++++ +LEN    LE   R L  R+++
Sbjct: 329 TLIPKSNDPDMRWNKGTILKASVDYIRKLQREQQRAK-ELENRQKKLEHANRHLLLRIQE 387

Query: 147 LQ 148
           L+
Sbjct: 388 LE 389


>gi|38156699 microphthalmia-associated transcription factor isoform
           1 [Homo sapiens]
          Length = 520

 Score = 37.7 bits (86), Expect = 0.008
 Identities = 33/122 (27%), Positives = 59/122 (48%), Gaps = 11/122 (9%)

Query: 37  MPSPRLQHSKP-PRRLSRAQKHSSGSSNTSTAN----RSTHNELEKNRRAHLRLCLERLK 91
           +P P L  S   P  L   ++  + S   + A     +  HN +E+ RR ++   ++ L 
Sbjct: 270 LPPPGLTISNSCPANLPNIKRELTESEARALAKERQKKDNHNLIERRRRFNINDRIKELG 329

Query: 92  VLIPLGPDCTRHTTLGLLNKAKA-HIKKLEEAERKSQHQLEN----LEREQRFLKWRLEQ 146
            LIP   D       G + KA   +I+KL+  +++++ +LEN    LE   R L  R+++
Sbjct: 330 TLIPKSNDPDMRWNKGTILKASVDYIRKLQREQQRAK-ELENRQKKLEHANRHLLLRIQE 388

Query: 147 LQ 148
           L+
Sbjct: 389 LE 390


>gi|38156697 microphthalmia-associated transcription factor isoform
           5 [Homo sapiens]
          Length = 413

 Score = 37.7 bits (86), Expect = 0.008
 Identities = 33/122 (27%), Positives = 59/122 (48%), Gaps = 11/122 (9%)

Query: 37  MPSPRLQHSKP-PRRLSRAQKHSSGSSNTSTAN----RSTHNELEKNRRAHLRLCLERLK 91
           +P P L  S   P  L   ++  + S   + A     +  HN +E+ RR ++   ++ L 
Sbjct: 163 LPPPGLTISNSCPANLPNIKRELTESEARALAKERQKKDNHNLIERRRRFNINDRIKELG 222

Query: 92  VLIPLGPDCTRHTTLGLLNKAKA-HIKKLEEAERKSQHQLEN----LEREQRFLKWRLEQ 146
            LIP   D       G + KA   +I+KL+  +++++ +LEN    LE   R L  R+++
Sbjct: 223 TLIPKSNDPDMRWNKGTILKASVDYIRKLQREQQRAK-ELENRQKKLEHANRHLLLRIQE 281

Query: 147 LQ 148
           L+
Sbjct: 282 LE 283


>gi|21704263 MAX protein isoform b [Homo sapiens]
          Length = 151

 Score = 37.7 bits (86), Expect = 0.008
 Identities = 30/125 (24%), Positives = 57/125 (45%), Gaps = 18/125 (14%)

Query: 69  RSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAERKSQH 128
           R+ HN LE+ RR H++     L+  +P      + +   +L+KA  +I+ +       Q 
Sbjct: 16  RAHHNALERKRRDHIKDSFHSLRDSVP-SLQGEKASRAQILDKATEYIQYMRRKNHTHQQ 74

Query: 129 QLENLEREQRFLKWRLEQLQG-----------PQEMERIRMDSIGSTISS------DRSD 171
            +++L+R+   L+ ++  L+            P     +  ++ GSTIS+        S+
Sbjct: 75  DIDDLKRQNALLEQQVRALEKARSSAQLQTNYPSSDNSLYTNAKGSTISAFDGGSDSSSE 134

Query: 172 SEREE 176
           SE EE
Sbjct: 135 SEPEE 139


>gi|21704261 MAX protein isoform a [Homo sapiens]
          Length = 160

 Score = 37.7 bits (86), Expect = 0.008
 Identities = 30/125 (24%), Positives = 57/125 (45%), Gaps = 18/125 (14%)

Query: 69  RSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAERKSQH 128
           R+ HN LE+ RR H++     L+  +P      + +   +L+KA  +I+ +       Q 
Sbjct: 25  RAHHNALERKRRDHIKDSFHSLRDSVP-SLQGEKASRAQILDKATEYIQYMRRKNHTHQQ 83

Query: 129 QLENLEREQRFLKWRLEQLQG-----------PQEMERIRMDSIGSTISS------DRSD 171
            +++L+R+   L+ ++  L+            P     +  ++ GSTIS+        S+
Sbjct: 84  DIDDLKRQNALLEQQVRALEKARSSAQLQTNYPSSDNSLYTNAKGSTISAFDGGSDSSSE 143

Query: 172 SEREE 176
           SE EE
Sbjct: 144 SEPEE 148


>gi|13540521 basic helix-loop-helix domain containing, class B, 3
           [Homo sapiens]
          Length = 482

 Score = 37.7 bits (86), Expect = 0.008
 Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 9/92 (9%)

Query: 56  KHSSGSSNTSTANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKA- 114
           K S    +T    +  H  +EK RR  +  C+ +LK L+   P+  + TTLG L KA   
Sbjct: 33  KRSMKRDDTKDTYKLPHRLIEKKRRDRINECIAQLKDLL---PEHLKLTTLGHLEKAVVL 89

Query: 115 -----HIKKLEEAERKSQHQLENLEREQRFLK 141
                H+K L     +   ++  L+  +R LK
Sbjct: 90  ELTLKHLKALTALTEQQHQKIIALQNGERSLK 121


>gi|4557755 microphthalmia-associated transcription factor isoform 4
           [Homo sapiens]
          Length = 419

 Score = 37.0 bits (84), Expect = 0.014
 Identities = 25/85 (29%), Positives = 46/85 (54%), Gaps = 6/85 (7%)

Query: 69  RSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKA-HIKKLEEAERKSQ 127
           +  HN +E+ RR ++   ++ L  LIP   D       G + KA   +I+KL+  +++++
Sbjct: 206 KDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTILKASVDYIRKLQREQQRAK 265

Query: 128 HQLEN----LEREQRFLKWRLEQLQ 148
            +LEN    LE   R L  R+++L+
Sbjct: 266 -ELENRQKKLEHANRHLLLRIQELE 289


>gi|58530842 desmoplakin isoform II [Homo sapiens]
          Length = 2272

 Score = 36.6 bits (83), Expect = 0.018
 Identities = 27/89 (30%), Positives = 43/89 (48%), Gaps = 9/89 (10%)

Query: 99   DCTRHTTLGLLNKAKAHIKKLEEAERKSQHQLENLEREQRFLKWRLEQLQGPQEMERIR- 157
            +C +      LN+ K    + EEA RK + + E  ERE+  L+  +E+LQ   E++RI  
Sbjct: 1255 ECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQA--EIKRIEE 1312

Query: 158  ------MDSIGSTISSDRSDSEREEIEVD 180
                   DS   T S   ++  R + E+D
Sbjct: 1313 RCRRKLEDSTRETQSQLETERSRYQREID 1341



 Score = 28.5 bits (62), Expect = 5.0
 Identities = 23/107 (21%), Positives = 52/107 (48%), Gaps = 13/107 (12%)

Query: 73   NELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAERKSQHQLEN 132
            N +++++    ++  ER  +L+ +           +L + KA +++LE+   +++  LE 
Sbjct: 1197 NRIQESKNQCTQVVQERESLLVKIK----------VLEQDKARLQRLEDELNRAKSTLEA 1246

Query: 133  LEREQRFLKWRLEQLQ---GPQEMERIRMDSIGSTISSDRSDSEREE 176
              R ++ L+   +Q+Q      + +  R +     I S+R  SERE+
Sbjct: 1247 ETRVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREK 1293


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.126    0.345 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,501,896
Number of Sequences: 37866
Number of extensions: 361741
Number of successful extensions: 2805
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 76
Number of HSP's successfully gapped in prelim test: 217
Number of HSP's that attempted gapping in prelim test: 2406
Number of HSP's gapped (non-prelim): 563
length of query: 228
length of database: 18,247,518
effective HSP length: 99
effective length of query: 129
effective length of database: 14,498,784
effective search space: 1870343136
effective search space used: 1870343136
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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