Guide to the Human Genome
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Search of human proteins with 56606131

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|56606131 tubulin tyrosine ligase-like family, member 9 [Homo
sapiens]
         (439 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|56606131 tubulin tyrosine ligase-like family, member 9 [Homo ...   915   0.0  
gi|11068135 tubulin tyrosine ligase-like family, member 1 [Homo ...   287   2e-77
gi|195963418 tubulin tyrosine ligase-like family, member 6 isofo...   158   1e-38
gi|99028883 tubulin tyrosine ligase-like family, member 2 [Homo ...   154   2e-37
gi|50658079 tubulin tyrosine ligase-like family, member 5 [Homo ...   145   7e-35
gi|75677580 tubulin tyrosine ligase-like family, member 13 [Homo...   145   9e-35
gi|217330594 tubulin tyrosine ligase-like family, member 4 [Homo...   132   5e-31
gi|94536793 tubulin tyrosine ligase-like family, member 7 [Homo ...   127   2e-29
gi|194239681 tubulin tyrosine ligase-like family, member 10 isof...   101   2e-21
gi|109134340 tubulin tyrosine ligase-like family, member 3 [Homo...    99   6e-21
gi|122937293 tubulin tyrosine ligase-like family, member 8 [Homo...    95   1e-19
gi|24308516 tubulin tyrosine ligase [Homo sapiens]                     83   6e-16
gi|212720861 tubulin tyrosine ligase-like family, member 11 a [H...    79   8e-15
gi|195963416 tubulin tyrosine ligase-like family, member 6 isofo...    79   1e-14
gi|194239678 tubulin tyrosine ligase-like family, member 10 isof...    78   1e-14
gi|89363028 tubulin tyrosine ligase-like family, member 11 b [Ho...    51   2e-06
gi|22550104 ubiquitin specific protease 32 [Homo sapiens]              32   1.1  
gi|5174617 nucleotide-binding oligomerization domain containing ...    31   2.5  
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap...    30   4.3  
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]    30   4.3  
gi|169207756 PREDICTED: hypothetical protein [Homo sapiens]            30   5.7  
gi|169207046 PREDICTED: hypothetical protein [Homo sapiens]            30   5.7  
gi|21536346 T-cell leukemia/lymphoma 6 isoform TCL6d1 [Homo sapi...    30   5.7  
gi|155722987 elongation factor, RNA polymerase II, 2 [Homo sapiens]    30   5.7  
gi|169207319 PREDICTED: hypothetical protein [Homo sapiens]            29   7.4  
gi|110347451 platelet/endothelial cell adhesion molecule [Homo s...    29   9.7  
gi|118918407 spectrin repeat containing, nuclear envelope 2 isof...    29   9.7  
gi|118918403 spectrin repeat containing, nuclear envelope 2 isof...    29   9.7  

>gi|56606131 tubulin tyrosine ligase-like family, member 9 [Homo
           sapiens]
          Length = 439

 Score =  915 bits (2364), Expect = 0.0
 Identities = 439/439 (100%), Positives = 439/439 (100%)

Query: 1   MVPSREALLGPGTTAIRCPKKLQNQNYKGHGLSKGKEREQRASIRFKTTLMNTLMDVLRH 60
           MVPSREALLGPGTTAIRCPKKLQNQNYKGHGLSKGKEREQRASIRFKTTLMNTLMDVLRH
Sbjct: 1   MVPSREALLGPGTTAIRCPKKLQNQNYKGHGLSKGKEREQRASIRFKTTLMNTLMDVLRH 60

Query: 61  RPGWVEVKDEGEWDFYWCDVSWLRENFDHTYMDEHVRISHFRNHYELTRKNYMVKNLKRF 120
           RPGWVEVKDEGEWDFYWCDVSWLRENFDHTYMDEHVRISHFRNHYELTRKNYMVKNLKRF
Sbjct: 61  RPGWVEVKDEGEWDFYWCDVSWLRENFDHTYMDEHVRISHFRNHYELTRKNYMVKNLKRF 120

Query: 121 RKQLEREAGKLEAAKCDFFPKTFEMPCEYHLFVEEFRKNPGITWIMKPVARSQGKGIFLF 180
           RKQLEREAGKLEAAKCDFFPKTFEMPCEYHLFVEEFRKNPGITWIMKPVARSQGKGIFLF
Sbjct: 121 RKQLEREAGKLEAAKCDFFPKTFEMPCEYHLFVEEFRKNPGITWIMKPVARSQGKGIFLF 180

Query: 181 RRLKDIVDWRKDTRSSDDQKDDIPVENYVAQRYIENPYLIGGRKFDLRVYVLVMSVFAEC 240
           RRLKDIVDWRKDTRSSDDQKDDIPVENYVAQRYIENPYLIGGRKFDLRVYVLVMSVFAEC
Sbjct: 181 RRLKDIVDWRKDTRSSDDQKDDIPVENYVAQRYIENPYLIGGRKFDLRVYVLVMSVFAEC 240

Query: 241 LLWSGHRRQDVHLTNVAVQKTSPDYHPKKGCKWTLQRFRQYLASKHGPEAVETLFRDIDN 300
           LLWSGHRRQDVHLTNVAVQKTSPDYHPKKGCKWTLQRFRQYLASKHGPEAVETLFRDIDN
Sbjct: 241 LLWSGHRRQDVHLTNVAVQKTSPDYHPKKGCKWTLQRFRQYLASKHGPEAVETLFRDIDN 300

Query: 301 IFVKSLQSVQKVIISDKHCFELYGYDILIDQDLKPWLLEVNASPSLTASSQEDYELKTCL 360
           IFVKSLQSVQKVIISDKHCFELYGYDILIDQDLKPWLLEVNASPSLTASSQEDYELKTCL
Sbjct: 301 IFVKSLQSVQKVIISDKHCFELYGYDILIDQDLKPWLLEVNASPSLTASSQEDYELKTCL 360

Query: 361 LEDTLHVVDMEARLTGREKRVGGFDLMWNDGPVSREEGAPDLSGMGNFVTNTHLGCVNDR 420
           LEDTLHVVDMEARLTGREKRVGGFDLMWNDGPVSREEGAPDLSGMGNFVTNTHLGCVNDR
Sbjct: 361 LEDTLHVVDMEARLTGREKRVGGFDLMWNDGPVSREEGAPDLSGMGNFVTNTHLGCVNDR 420

Query: 421 KKQLRQLFCSLQVQKKASS 439
           KKQLRQLFCSLQVQKKASS
Sbjct: 421 KKQLRQLFCSLQVQKKASS 439


>gi|11068135 tubulin tyrosine ligase-like family, member 1 [Homo
           sapiens]
          Length = 423

 Score =  287 bits (734), Expect = 2e-77
 Identities = 164/374 (43%), Positives = 215/374 (57%), Gaps = 44/374 (11%)

Query: 47  KTTLMNTLMDVLRHRPGWVEVKDEGEWDFYWCDVSWLRENFD----HTYMDEHVRISHFR 102
           K+ L+N        + GWV+V +  +W+FYW  V  +R  F     +   D+ + ++HF 
Sbjct: 13  KSVLINNF-----EKRGWVQVTENEDWNFYWMSVQTIRNVFSVEAGYRLSDDQI-VNHFP 66

Query: 103 NHYELTRKNYMVKNLKRFRKQLEREAGKL----EAAK---CDFFPKTFEMPCEYHLFVEE 155
           NHYELTRK+ MVKN+KR+RK+LE+E   L    E  K    DF P T+ +P +Y+LFVEE
Sbjct: 67  NHYELTRKDLMVKNIKRYRKELEKEGSPLAEKDENGKYLYLDFVPVTYMLPADYNLFVEE 126

Query: 156 FRKNPGITWIMKPVARSQGKGIFLFRRLKDIVDWRKDTRSSDDQKDDIPVENYVAQRYIE 215
           FRK+P  TWIMKP  ++QGKGIFL  +L  I  W +D+++S         E YV   YI 
Sbjct: 127 FRKSPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSNK-EAYVISLYIN 185

Query: 216 NPYLIGGRKFDLRVYVLVMSVFA-ECLLW----------------SGHRRQDVHLTNVAV 258
           NP LIGGRKFDLR+YVLV +     C ++                S      VHLTNVA+
Sbjct: 186 NPLLIGGRKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHLTNVAI 245

Query: 259 QKTSPDYHPKKGCKWTLQRFRQYLASKHGPEAVETLFRDIDNIFVKSLQSVQKVIISDKH 318
           QK   DY+   G KWT+   R YL S  G E    LF +I  I V+SL++V  V+ +DKH
Sbjct: 246 QKHGEDYNHIHGGKWTVSNLRLYLESTRGKEVTSKLFDEIHWIIVQSLKAVAPVMNNDKH 305

Query: 319 CFELYGYDILIDQDLKPWLLEVNASPSLTASSQEDYELKTCLLEDTLHVVDMEARLTGRE 378
           CFE YGYDI+ID  LKPWL+EVNASPSLT+S+  D  LK  L+ DTL++      +    
Sbjct: 306 CFECYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIAVPNGEIP--- 362

Query: 379 KRVGGFDLMWNDGP 392
                 D  WN  P
Sbjct: 363 ------DCKWNKSP 370


>gi|195963418 tubulin tyrosine ligase-like family, member 6 isoform
           1 [Homo sapiens]
          Length = 891

 Score =  158 bits (399), Expect = 1e-38
 Identities = 120/382 (31%), Positives = 186/382 (48%), Gaps = 64/382 (16%)

Query: 22  LQNQNYKGHGLSKGKEREQRASIRFKTTLMNTLMDVLRHRPGWVEVKDEGEWDFYWCDVS 81
           LQN   +G    K K +++R  I   +    ++    +   G+ E  ++ +W  YW D S
Sbjct: 93  LQNAQQQG----KKKRKKKRLVINLSSCRYESVRRAAQQY-GFREGGEDDDWTLYWTDYS 147

Query: 82  WLRENFDHTYMDEHVRISHFRNHYELTRKNYMVKNLKRFRKQLEREAGKLEAAKCDFFPK 141
              E      M  + +I+HF    E+ RK+ + +N+ R  K   ++          FFP+
Sbjct: 148 VSLERVME--MKSYQKINHFPGMSEICRKDLLARNMSRMLKMFPKDFR--------FFPR 197

Query: 142 TFEMPCEYHLFVEEFRKNPGITWIMKPVARSQGKGIFLFRRLKDIVDWRKDTRSSDDQKD 201
           T+ +P ++       R     T+I KP +  QGKGIF+ R +K+I               
Sbjct: 198 TWCLPADWGDLQTYSRSRKNKTYICKPDSGCQGKGIFITRTVKEIK-------------- 243

Query: 202 DIPVENYVAQRYIENPYLIGGRKFDLRVYVLVMS-------VFAECL---LWSGHRR--- 248
             P E+ + Q YI  P++I G KFDLR+YVLV S       V+ E L     + + R   
Sbjct: 244 --PGEDMICQLYISKPFIIDGFKFDLRIYVLVTSCDPLRIFVYNEGLARFATTSYSRPCT 301

Query: 249 ---QDV--HLTNVAVQKTSPDY--HPKKGCKWTLQRFRQYLASKHGPEAVETLFRDIDNI 301
               D+  HLTN ++ K S ++      G K  L  F  YL  +     VE ++RDI+++
Sbjct: 302 DNLDDICMHLTNYSINKHSSNFSRDAHSGSKRKLSTFSAYL--EDHSYNVEQIWRDIEDV 359

Query: 302 FVKSLQSVQKVIISDKH-----------CFELYGYDILIDQDLKPWLLEVNASPSLTASS 350
            +K+L S   +I  + H           CFE+ G+DIL+D  LKPWLLEVN SPS +  S
Sbjct: 360 IIKTLISAHPIIRHNYHTCFPNHTLNSACFEILGFDILLDHKLKPWLLEVNHSPSFSTDS 419

Query: 351 QEDYELKTCLLEDTLHVVDMEA 372
           + D E+K  LL DTL ++++E+
Sbjct: 420 RLDKEVKDGLLYDTLVLINLES 441


>gi|99028883 tubulin tyrosine ligase-like family, member 2 [Homo
           sapiens]
          Length = 592

 Score =  154 bits (389), Expect = 2e-37
 Identities = 115/365 (31%), Positives = 175/365 (47%), Gaps = 59/365 (16%)

Query: 45  RFKTTLMNTLMDVLRHRPGW----VEVKDEGEWDFYWCDVSWLRENFDHTYMDEHVRISH 100
           R   T    +  VL  R GW     + ++  +W+ YW   S+     +H  +    +++H
Sbjct: 90  RVDETTPAVVQSVLLER-GWNKFDKQEQNAEDWNLYWRTSSFRMT--EHNSVKPWQQLNH 146

Query: 101 FRNHYELTRKNYMVKNLKRFRKQLEREAGKLEAAKCDFFPKTFEMPCEYHLFVEEFRKNP 160
                +LTRK+ + K+LK  R+           +   F P TF MP +Y  FV E+ +  
Sbjct: 147 HPGTTKLTRKDCLAKHLKHMRRMYG-------TSLYQFIPLTFVMPNDYTKFVAEYFQER 199

Query: 161 GIT------WIMKPVARSQGKGIFLFRRLKDIVDWRKDTRSSDDQKDDIPVENYVAQRYI 214
            +       WI KP   S+G+GI +F   KD +             DD+    Y+ Q+YI
Sbjct: 200 QMLGTKHSYWICKPAELSRGRGILIFSDFKDFIF------------DDM----YIVQKYI 243

Query: 215 ENPYLIGGRKFDLRVYV-------LVMSVFAECLLWSGHRRQDV--------HLTNVAVQ 259
            NP LIG  K DLR+YV       L + V+ E L+     + D+        HLTN ++ 
Sbjct: 244 SNPLLIGRYKCDLRIYVCVTGFKPLTIYVYQEGLVRFATEKFDLSNLQNNYAHLTNSSIN 303

Query: 260 KTSPDYHPKK-----GCKWTLQRFRQYLASKHGPEAVETLFRDIDNIFVKSLQSVQKVII 314
           K+   Y   K     GCKWTL RF  YL S    + +  L++ I  + + ++ ++   + 
Sbjct: 304 KSGASYEKIKEVIGHGCKWTLSRFFSYLRSWDVDDLL--LWKKIHRMVILTILAIAPSVP 361

Query: 315 SDKHCFELYGYDILIDQDLKPWLLEVNASPSLTASSQEDYELKTCLLEDTLHVVDMEA-R 373
              +CFEL+G+DILID +LKPWLLEVN SP+LT     D  +K  L+ D + ++ +   R
Sbjct: 362 FAANCFELFGFDILIDDNLKPWLLEVNYSPALTLDCSTDVLVKRKLVHDIIDLIYLNGLR 421

Query: 374 LTGRE 378
             GRE
Sbjct: 422 NEGRE 426


>gi|50658079 tubulin tyrosine ligase-like family, member 5 [Homo
           sapiens]
          Length = 1281

 Score =  145 bits (366), Expect = 7e-35
 Identities = 104/309 (33%), Positives = 148/309 (47%), Gaps = 58/309 (18%)

Query: 92  MDEHVRISHFRNHYELTRKNYMVKNLKRFRKQLEREAGKLEAAKCDFFPKTFEMPCEYHL 151
           + E  +++HF   YELTRK+ + KN+ R +     +A  +        P+TF +P EY  
Sbjct: 113 LSEAQKVNHFPRSYELTRKDRLYKNIIRMQHTHGFKAFHI-------LPQTFLLPAEYAE 165

Query: 152 FVEEFRKNPGITWIMKPVARSQGKGIFLFRRLKDIVDWRKDTRSSDDQKDDIPVENYVAQ 211
           F   + K+ G  WI+KPVA S+G+G++L      I                   EN +  
Sbjct: 166 FCNSYSKDRG-PWIVKPVASSRGRGVYLINNPNQIS----------------LEENILVS 208

Query: 212 RYIENPYLIGGRKFDLRVYVLVMSV--------------FAECLLWSGH---RRQDVHLT 254
           RYI NP LI   KFD+R+YVLV S               FA      G    R Q +HLT
Sbjct: 209 RYINNPLLIDDFKFDVRLYVLVTSYDPLVIYLYEEGLARFATVRYDQGAKNIRNQFMHLT 268

Query: 255 NVAVQKTSPDY----HPKK---GCKWTLQRFRQYLASKHGPEAVETLFRDIDNIFVKSLQ 307
           N +V K S DY     P+    G KW++    +YL  K        L   ++++ +K++ 
Sbjct: 269 NYSVNKKSGDYVSCDDPEVEDYGNKWSMSAMLRYL--KQEGRDTTALMAHVEDLIIKTII 326

Query: 308 SVQKVIISD--------KHCFELYGYDILIDQDLKPWLLEVNASPSLTASSQEDYELKTC 359
           S +  I +           CFELYG+D+LID  LKPWLLEVN SPSL   +  D ++K  
Sbjct: 327 SAELAIATACKTFVPHRSSCFELYGFDVLIDSTLKPWLLEVNLSPSLACDAPLDLKIKAS 386

Query: 360 LLEDTLHVV 368
           ++ D   VV
Sbjct: 387 MISDMFTVV 395


>gi|75677580 tubulin tyrosine ligase-like family, member 13 [Homo
           sapiens]
          Length = 459

 Score =  145 bits (365), Expect = 9e-35
 Identities = 124/402 (30%), Positives = 184/402 (45%), Gaps = 69/402 (17%)

Query: 15  AIRCPKKLQNQNYKGHGLSKGKEREQRASIRFKTTLMNTLMDVLRHRP---GWVEVKDEG 71
           A + PKK+      G  L  G+ + +R        L N   + +R      G  EV ++ 
Sbjct: 58  ATKIPKKVIAPVDTGD-LEAGRRKRRRKRRSLAINLTNCKYESVRRAAQMCGLKEVGEDE 116

Query: 72  EWDFYWCDVSWLRENFDHTYMDEHVRISHFRNHYELTRKNYMVKNLKRFRKQLEREAGKL 131
           EW  YW D +   E      M    +I+HF    E+ RK+ + +NL R  K        L
Sbjct: 117 EWTLYWTDCAVSLERVMD--MKRFQKINHFPGMTEICRKDLLARNLNRMYK--------L 166

Query: 132 EAAKCDFFPKTFEMPCEYHLFVEEFRKNPGITWIMKPVARSQGKGIFLFRRLKDIVDWRK 191
             ++ + FP+T+ +P +Y  F    R+    T+I KP +  QG+GIF+ R  ++I     
Sbjct: 167 YPSEYNIFPRTWCLPADYGDFQSYGRQRKARTYICKPDSGCQGRGIFITRNPREIK---- 222

Query: 192 DTRSSDDQKDDIPVENYVAQRYIENPYLIGGRKFDLRVYVLVMS-------VFAECL--- 241
                       P E+ + Q+YI  P LI G KFD+RVYVL+ S        + E L   
Sbjct: 223 ------------PGEHMICQQYISKPLLIDGFKFDMRVYVLITSCDPLRIFTYEEGLARF 270

Query: 242 -----LWSGHRRQD---VHLTNVAVQKTSPDY--HPKKGCKWTLQRFRQYLASKHGPEAV 291
                +   H   D   +HLTN A+ K + ++      G K  L     +L  +H     
Sbjct: 271 ATTPYMEPSHNNLDNVCMHLTNYAINKHNENFVRDGAVGSKRKLSTLNIWL-QEHSYNPG 329

Query: 292 ETLFRDIDNIFVKSLQSVQKVIISDKH-------------CFELYGYDILIDQDLKPWLL 338
           E L+ DI++I +K++ S   V+  +               CFE+ G+DIL+D  LKPWLL
Sbjct: 330 E-LWGDIEDIIIKTIISAHSVLRHNYRTCFPQYLNGGTCACFEILGFDILLDHKLKPWLL 388

Query: 339 EVNASPSLTASSQEDYELKTCLLEDTLHVVDMEARLTGREKR 380
           EVN SPS T  S  D E+K  LL D + +V+    L G +KR
Sbjct: 389 EVNHSPSFTTDSCLDQEVKDALLCDAMTLVN----LRGCDKR 426


>gi|217330594 tubulin tyrosine ligase-like family, member 4 [Homo
           sapiens]
          Length = 1199

 Score =  132 bits (333), Expect = 5e-31
 Identities = 92/305 (30%), Positives = 152/305 (49%), Gaps = 56/305 (18%)

Query: 94  EHVRISHFRNHYELTRKNYMVKNLKRFRKQLEREAGKLEAAKCDFFPKTFEMPCEYHLFV 153
           EH +++HF   +++ RK+ + +NL R + +     GK E +   FFP++F +P +  L  
Sbjct: 655 EHQKLNHFPGSFQIGRKDRLWRNLSRMQSRF----GKKEFS---FFPQSFILPQDAKLLR 707

Query: 154 EEFRKNPGITWIMKPVARSQGKGIFLFRRLKDIVDWRKDTRSSDDQKDDIPVENYVAQRY 213
           + +  +    WI+KP A ++G GI +  +   +   R                  + QRY
Sbjct: 708 KAWESSSRQKWIVKPPASARGIGIQVIHKWSQLPKRRP----------------LLVQRY 751

Query: 214 IENPYLIGGRKFDLRVYVLVMSV--------------FAECLLWSGHR---RQDVHLTNV 256
           +  PYLI G KFDLR+YV V S               FA C      +    + +HLTN 
Sbjct: 752 LHKPYLISGSKFDLRIYVYVTSYDPLRIYLFSDGLVRFASCKYSPSMKSLGNKFMHLTNY 811

Query: 257 AVQKTSPDYHPK------KGCKWTLQRFRQYLASKHGPEAVETLFRDIDNIFVKSLQSVQ 310
           +V K + +Y         +G KW L+    YL+ K G  + + ++  I ++ VK++ S +
Sbjct: 812 SVNKKNAEYQANADEMACQGHKWALKALWNYLSQK-GVNS-DAIWEKIKDVVVKTIISSE 869

Query: 311 KVIIS--------DKHCFELYGYDILIDQDLKPWLLEVNASPSLTASSQEDYELKTCLLE 362
             + S           C EL+G+DI++D++LKPW+LEVN SPSL +SS  D  +K  ++ 
Sbjct: 870 PYVTSLLKMYVRRPYSCHELFGFDIMLDENLKPWVLEVNISPSLHSSSPLDISIKGQMIR 929

Query: 363 DTLHV 367
           D L++
Sbjct: 930 DLLNL 934


>gi|94536793 tubulin tyrosine ligase-like family, member 7 [Homo
           sapiens]
          Length = 887

 Score =  127 bits (320), Expect = 2e-29
 Identities = 104/382 (27%), Positives = 182/382 (47%), Gaps = 75/382 (19%)

Query: 34  KGKEREQRASIRFKTTLMNTLMDVLR---HRPGWVEVKDEGEW-DFYWCDVSWLRENFDH 89
           K K R+++        +  T  +++R      G+++  DE E  +  WCD +  +E    
Sbjct: 29  KRKVRKKKKKGTITANVAGTKFEIVRLVIDEMGFMKTPDEDETSNLIWCDSAVQQEKISE 88

Query: 90  TYMDEHVRISHFRNHYELTRKNYMVKNLKRFRKQLEREAGKLEAAKCDFFPKTFEMPCEY 149
             +  + RI+HF    E+ RK+++ +N+ +  K    +          F P+T+  P EY
Sbjct: 89  --LQNYQRINHFPGMGEICRKDFLARNMTKMIKSRPLDY--------TFVPRTWIFPAEY 138

Query: 150 HLF---VEEFRKN-PGITWIMKPVARSQGKGIFLFRRLKDIVDWRKDTRSSDDQKDDIPV 205
             F   V+E +K     T+I+KP   + G GI L R                   D +P 
Sbjct: 139 TQFQNYVKELKKKRKQKTFIVKPANGAMGHGISLIRN-----------------GDKLPS 181

Query: 206 ENY-VAQRYIENPYLIGGRKFDLRVYVLVMS-------VFAECLLWSGHRRQD------- 250
           +++ + Q YIE P+L+ G KFDLR+Y+LV S       ++ + L+  G  +         
Sbjct: 182 QDHLIVQEYIEKPFLMEGYKFDLRIYILVTSCDPLKIFLYHDGLVRMGTEKYIPPNESNL 241

Query: 251 ----VHLTNVAVQKTSPDYH----PKKGCKWTLQRFRQYL-ASKHGPEAVETLFRDIDNI 301
               +HLTN +V K +  +       KG K +++ F ++L A++H    V   + DI  +
Sbjct: 242 TQLYMHLTNYSVNKHNEHFERDETENKGSKRSIKWFTEFLQANQHD---VAKFWSDISEL 298

Query: 302 FVKSLQSVQKVII-------------SDKHCFELYGYDILIDQDLKPWLLEVNASPSLTA 348
            VK+L   +  ++             S+  CFE+ G+DIL+D+ LKPWLLE+N +PS   
Sbjct: 299 VVKTLIVAEPHVLHAYRMCRPGQPPGSESVCFEVLGFDILLDRKLKPWLLEINRAPSFGT 358

Query: 349 SSQEDYELKTCLLEDTLHVVDM 370
             + DY++K  +L + L ++++
Sbjct: 359 DQKIDYDVKRGVLLNALKLLNI 380


>gi|194239681 tubulin tyrosine ligase-like family, member 10 isoform
           1 [Homo sapiens]
          Length = 673

 Score =  101 bits (251), Expect = 2e-21
 Identities = 76/264 (28%), Positives = 126/264 (47%), Gaps = 38/264 (14%)

Query: 137 DFFPKTFEMPCEYH--LFVEEFRKNPGITWIMKPVARSQGKGIFLFRRLKDIVDWRKDTR 194
           +FFP+T+ +  ++    F   F +     WI KP A +QGKGIFL R  +++   +  TR
Sbjct: 283 EFFPETYRLDLKHEREAFFTLFDETQ--IWICKPTASNQGKGIFLLRNQEEVAALQAKTR 340

Query: 195 SSDDQKDDIPVENY---------VAQRYIENPYLIGGRKFDLRVYVLVMSVFAECLLWS- 244
           S +D     P+ +          V QRYI+NP L+ GRKFD+R Y+L+       + +  
Sbjct: 341 SMEDD----PIHHKTPFRGPQARVVQRYIQNPLLVDGRKFDVRSYLLIACTTPYMIFFGH 396

Query: 245 GHRRQDV------------HLTNVAVQKTSPDYH-PKKGCKWTLQRFRQYLASKHGPE-- 289
           G+ R  +            HLTN  +QK SP Y   K+   W+++   +Y++        
Sbjct: 397 GYARLTLSLYDPHSSDLGGHLTNQFMQKKSPLYMLLKEHTVWSMEHLNRYISDTFWKARG 456

Query: 290 -----AVETLFRDIDNIFVKSLQSVQKVIISDKHCFELYGYDILIDQDLKPWLLEVNASP 344
                   TL + +  I      + +  +      F+L G D LID + K WLLE+N++P
Sbjct: 457 LAKDWVFTTLKKRMQQIMAHCFLAAKPKLDCKLGYFDLIGCDFLIDDNFKVWLLEMNSNP 516

Query: 345 SLTASSQEDYELKTCLLEDTLHVV 368
           +L  + +   E+   ++ +TL +V
Sbjct: 517 ALHTNCEVLKEVIPGVVIETLDLV 540


>gi|109134340 tubulin tyrosine ligase-like family, member 3 [Homo
           sapiens]
          Length = 772

 Score = 99.4 bits (246), Expect = 6e-21
 Identities = 78/251 (31%), Positives = 119/251 (47%), Gaps = 30/251 (11%)

Query: 164 WIMKPVARSQGKGIFLFRRLKDIVDWRKDTRSSDDQKDDIPVENYVAQRYIENPYLIGGR 223
           WI+KP A+S+G+GI     L++++  +    +    KD      +V Q+YIE P LI G 
Sbjct: 280 WIVKPGAKSRGRGIMCMDHLEEML--KLVNGNPVVMKDG----KWVVQKYIERPLLIFGT 333

Query: 224 KFDLRVYVLVMSVFAECLLWS---------------GHRRQDVHLTNVAVQK---TSPDY 265
           KFDLR + LV   +    +W                 +    VHL N ++QK    S   
Sbjct: 334 KFDLRQWFLVTD-WNPLTVWFYRDSYIRFSTQPFSLKNLDNSVHLCNNSIQKHLENSCHR 392

Query: 266 HP--KKGCKWTLQRFRQYLASKHGPEAVETLF-RDIDNIFVKSLQSVQKVIISDKHCFEL 322
           HP       W+ QRF+ +L     P A  T+    + +  + +LQ+ Q  +   K  FEL
Sbjct: 393 HPLLPPDNMWSSQRFQAHLQEMGAPNAWSTIIVPGMKDAVIHALQTSQDTVQCRKASFEL 452

Query: 323 YGYDILIDQDLKPWLLEVNASPSLTASSQEDYELKTCLLEDTLHVVDMEARLTGREKRVG 382
           YG D +  +D +PWL+E+NASP++  S+     L   +  DTL VV    R+  R    G
Sbjct: 453 YGADFVFGEDFQPWLIEINASPTMAPSTAVTARLCAGVQADTLRVV--IDRMLDRNCDTG 510

Query: 383 GFDLMWNDGPV 393
            F+L++    V
Sbjct: 511 AFELIYKQPAV 521


>gi|122937293 tubulin tyrosine ligase-like family, member 8 [Homo
           sapiens]
          Length = 834

 Score = 94.7 bits (234), Expect = 1e-19
 Identities = 75/251 (29%), Positives = 120/251 (47%), Gaps = 40/251 (15%)

Query: 164 WIMKPVARSQGKG----IFLFRRLKDIVDWRK-DTRSSDDQKDDIPVENYVAQRYIENPY 218
           WI+KP A+S+G+G    I    R+++I++    D   S D K       +V Q+YIE P 
Sbjct: 331 WIIKPAAKSRGRGESPDIVCMDRVEEILELAAADHPLSRDNK-------WVVQKYIETPL 383

Query: 219 LIGGRKFDLRVYVLVMS-------VFAECLLWSGHRR-------QDVHLTNVAVQKTSPD 264
           LI   KFD+R + LV          + E  L    +R         +HL N AVQK   +
Sbjct: 384 LICDTKFDIRQWFLVTDWNPLTIWFYKESYLRFSTQRFSLDKLDSAIHLCNNAVQKYLKN 443

Query: 265 YHPKKGC-----KWTLQRFRQYLASKHGPEAV--ETLFRDIDNIFVKSLQSVQKVIISDK 317
              +         WT  RF++YL  + G  AV    ++  +      +++  Q  +   K
Sbjct: 444 DVGRSPLLPAHNMWTSTRFQEYL-QRQGRGAVWGSVIYPSMKKAIAHAMKVAQDHVEPRK 502

Query: 318 HCFELYGYDILIDQDLKPWLLEVNASPSLTASSQEDYELKTCLLEDTLHVVDMEARLTGR 377
           + FELYG D ++ +D +PWL+E+N+SP++  S+    +L   + EDT+ V         R
Sbjct: 503 NSFELYGADFVLGRDFRPWLIEINSSPTMHPSTPVTAQLCAQVQEDTIKVA------VDR 556

Query: 378 EKRVGGFDLMW 388
              +G F+L+W
Sbjct: 557 SCDIGNFELLW 567


>gi|24308516 tubulin tyrosine ligase [Homo sapiens]
          Length = 377

 Score = 82.8 bits (203), Expect = 6e-16
 Identities = 64/206 (31%), Positives = 102/206 (49%), Gaps = 33/206 (16%)

Query: 161 GITWIMKPVARSQGKGIFLFRRLKDIVDWRKDTRSSDDQKDDIPVENYVAQRYIENPYLI 220
           G  WI K  A ++G+GI +     +++D+       D+Q      + +V Q+Y+E+P L+
Sbjct: 144 GNVWIAKSSAGAKGEGILISSEASELLDF------IDNQG-----QVHVIQKYLEHPLLL 192

Query: 221 --GGRKFDLRVYVLVMSVFAECLLWSGHRR-------------QDVHLTNVAVQKTSPDY 265
             G RKFD+R +VLV   +   L   G  R             +  HLTN  +QK     
Sbjct: 193 EPGHRKFDIRSWVLVDHQYNIYLYREGVLRTASEPYHVDNFQDKTCHLTNHCIQKEYSKN 252

Query: 266 HPK--KGCKWTLQRFRQYLASKHGPEAVETLFRDIDNIFVKSLQSVQKVIISDKHC---- 319
           + K  +G +   + F QYL S        ++   I +I    L SV+  I S KH     
Sbjct: 253 YGKYEEGNEMFFKEFNQYLTSALNITLESSILLQIKHIIRNCLLSVEPAI-STKHLPYQS 311

Query: 320 FELYGYDILIDQDLKPWLLEVNASPS 345
           F+L+G+D ++D++LK WL+EVN +P+
Sbjct: 312 FQLFGFDFMVDEELKVWLIEVNGAPA 337


>gi|212720861 tubulin tyrosine ligase-like family, member 11 a [Homo
           sapiens]
          Length = 800

 Score = 79.0 bits (193), Expect = 8e-15
 Identities = 87/337 (25%), Positives = 153/337 (45%), Gaps = 65/337 (19%)

Query: 78  CDVSWLRENFDHTYMDEHVRISHFRNHYELTRKNYMVKNLKRFRKQLEREAGKLEAAKCD 137
           CD+ W   +F H       +++ F    E+ RK  + + ++  +     E         +
Sbjct: 253 CDIYWHGVSF-HDNDIFSGQVNKFPGMTEMVRKITLSRAVRTMQNLFPEEY--------N 303

Query: 138 FFPKTFEMPCEYHLFVEEFR--KNPGITW----IMKPVARSQGKGIFLFRRLKDIVDWRK 191
           F+P+++ +P E+ LFV + +  K+   +W    I+KP    QG GI+L +   DI     
Sbjct: 304 FYPRSWILPDEFQLFVAQVQMVKDDDPSWKPTFIVKPDGGCQGDGIYLIKDPSDI----- 358

Query: 192 DTRSSDDQKDDIPVENYVAQRYIENPYLIGGRKFDLRVYVLVMSV--------------- 236
                      +     V Q YI  P LI   KFD+R+YVL+ S+               
Sbjct: 359 ------RLAGTLQSRPAVVQEYICKPLLIDKLKFDIRLYVLLKSLDPLEIYIAKDGLSRF 412

Query: 237 ----FAECLLWSGHRRQDVHLTNVAVQKTSPDY----HPKKGCKWTLQRFRQYLASKHGP 288
               + E    + HR   +HLTN ++   S ++        G K T       L+SK G 
Sbjct: 413 CTEPYQEPTPKNLHRIF-MHLTNYSLNIHSGNFIHSDSASTGSKRTFSSILCRLSSK-GV 470

Query: 289 EAVETLFRDIDNIFVKSLQSVQ---KVIISDK--------HCFELYGYDILIDQDLKPWL 337
           + ++ ++ DI ++ +K++ ++    KV              CF++ G+DIL+ ++LKP L
Sbjct: 471 D-IKKVWSDIISVVIKTVIALTPELKVFYQSDIPTGRPGPTCFQILGFDILLMKNLKPIL 529

Query: 338 LEVNASPSLTASSQEDYELKTCLLEDTLHVVDMEARL 374
           LEVNA+PS+    + ++EL   + E+   +VD E ++
Sbjct: 530 LEVNANPSMRI--EHEHELSPGVFENVPSLVDEEVKV 564


>gi|195963416 tubulin tyrosine ligase-like family, member 6 isoform
           2 [Homo sapiens]
          Length = 584

 Score = 78.6 bits (192), Expect = 1e-14
 Identities = 40/93 (43%), Positives = 60/93 (64%), Gaps = 11/93 (11%)

Query: 291 VETLFRDIDNIFVKSLQSVQKVIISDKH-----------CFELYGYDILIDQDLKPWLLE 339
           VE ++RDI+++ +K+L S   +I  + H           CFE+ G+DIL+D  LKPWLLE
Sbjct: 42  VEQIWRDIEDVIIKTLISAHPIIRHNYHTCFPNHTLNSACFEILGFDILLDHKLKPWLLE 101

Query: 340 VNASPSLTASSQEDYELKTCLLEDTLHVVDMEA 372
           VN SPS +  S+ D E+K  LL DTL ++++E+
Sbjct: 102 VNHSPSFSTDSRLDKEVKDGLLYDTLVLINLES 134


>gi|194239678 tubulin tyrosine ligase-like family, member 10 isoform
           2 [Homo sapiens]
          Length = 404

 Score = 78.2 bits (191), Expect = 1e-14
 Identities = 54/172 (31%), Positives = 86/172 (50%), Gaps = 31/172 (18%)

Query: 137 DFFPKTFEMPCEYH--LFVEEFRKNPGITWIMKPVARSQGKGIFLFRRLKDIVDWRKDTR 194
           +FFP+T+ +  ++    F   F +     WI KP A +QGKGIFL R  +++   +  TR
Sbjct: 210 EFFPETYRLDLKHEREAFFTLFDETQ--IWICKPTASNQGKGIFLLRNQEEVAALQAKTR 267

Query: 195 SSDDQKDDIPVENY---------VAQRYIENPYLIGGRKFDLRVYVLVMSVFAECLLWS- 244
           S +D     P+ +          V QRYI+NP L+ GRKFD+R Y+L+       + +  
Sbjct: 268 SMEDD----PIHHKTPFRGPQARVVQRYIQNPLLVDGRKFDVRSYLLIACTTPYMIFFGH 323

Query: 245 GHRRQDV------------HLTNVAVQKTSPDYH-PKKGCKWTLQRFRQYLA 283
           G+ R  +            HLTN  +QK SP Y   K+   W+++   +Y++
Sbjct: 324 GYARLTLSLYDPHSSDLGGHLTNQFMQKKSPLYMLLKEHTVWSMEHLNRYIS 375


>gi|89363028 tubulin tyrosine ligase-like family, member 11 b [Homo
           sapiens]
          Length = 538

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 44/165 (26%), Positives = 74/165 (44%), Gaps = 26/165 (15%)

Query: 78  CDVSWLRENFDHTYMDEHVRISHFRNHYELTRKNYMVKNLKRFRKQLEREAGKLEAAKCD 137
           CD+ W   +F H       +++ F    E+ RK  + + ++  +     E         +
Sbjct: 253 CDIYWHGVSF-HDNDIFSGQVNKFPGMTEMVRKITLSRAVRTMQNLFPEEY--------N 303

Query: 138 FFPKTFEMPCEYHLFVEEFR--KNPGITW----IMKPVARSQGKGIFLFRRLKDIVDWRK 191
           F+P+++ +P E+ LFV + +  K+   +W    I+KP    QG GI+L +   DI     
Sbjct: 304 FYPRSWILPDEFQLFVAQVQMVKDDDPSWKPTFIVKPDGGCQGDGIYLIKDPSDI----- 358

Query: 192 DTRSSDDQKDDIPVENYVAQRYIENPYLIGGRKFDLRVYVLVMSV 236
                      +     V Q YI  P LI   KFD+R+YVL+ S+
Sbjct: 359 ------RLAGTLQSRPAVVQEYICKPLLIDKLKFDIRLYVLLKSL 397


>gi|22550104 ubiquitin specific protease 32 [Homo sapiens]
          Length = 1604

 Score = 32.0 bits (71), Expect = 1.1
 Identities = 32/115 (27%), Positives = 53/115 (46%), Gaps = 27/115 (23%)

Query: 330 DQDLKPWLLEVNASPSLTASSQEDYELKTCLLEDTLHVVDMEARLTGREKRVGGFDLMW- 388
           ++D++ WL   N+   LT    ED++L+   ++D  H+V +E R           D+ W 
Sbjct: 663 EEDMRLWLY--NSENYLTLLDDEDHKLEYLKIQDEQHLV-IEVR---------NKDMSWP 710

Query: 389 -------NDGPVSR-----EEGAPDLSGMGN-FVTNTHLGCVNDRKKQLRQLFCS 430
                  N   + R     E+GA  LS +GN    N+ + CV++  + L Q F S
Sbjct: 711 EEMSFIANSSKIDRHKVPTEKGATGLSNLGNTCFMNSSIQCVSN-TQPLTQYFIS 764


>gi|5174617 nucleotide-binding oligomerization domain containing 1
           [Homo sapiens]
          Length = 953

 Score = 30.8 bits (68), Expect = 2.5
 Identities = 17/34 (50%), Positives = 20/34 (58%), Gaps = 2/34 (5%)

Query: 320 FELYGYDILIDQ--DLKPWLLEVNASPSLTASSQ 351
           F LY    L D   DL+PWLLE+  SPSL   S+
Sbjct: 85  FFLYLLQQLADAYVDLRPWLLEIGFSPSLLTQSK 118


>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
           sapiens]
          Length = 1116

 Score = 30.0 bits (66), Expect = 4.3
 Identities = 25/73 (34%), Positives = 39/73 (53%), Gaps = 6/73 (8%)

Query: 330 DQDLKPWLLEVNASPSLTA-SSQEDYELKTCLLEDTLHVVDMEARLTGREKRVGGFDLMW 388
           D+ +K  LLE+  S  L+A +++ED+E    L E  +HV  +E+ L  +EK     + M 
Sbjct: 306 DESIKK-LLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKE----NSML 360

Query: 389 NDGPVSREEGAPD 401
            +    R E APD
Sbjct: 361 REEMHRRFENAPD 373


>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
          Length = 1088

 Score = 30.0 bits (66), Expect = 4.3
 Identities = 25/73 (34%), Positives = 39/73 (53%), Gaps = 6/73 (8%)

Query: 330 DQDLKPWLLEVNASPSLTA-SSQEDYELKTCLLEDTLHVVDMEARLTGREKRVGGFDLMW 388
           D+ +K  LLE+  S  L+A +++ED+E    L E  +HV  +E+ L  +EK     + M 
Sbjct: 306 DESIKK-LLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKE----NSML 360

Query: 389 NDGPVSREEGAPD 401
            +    R E APD
Sbjct: 361 REEMHRRFENAPD 373


>gi|169207756 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 828

 Score = 29.6 bits (65), Expect = 5.7
 Identities = 44/200 (22%), Positives = 86/200 (43%), Gaps = 22/200 (11%)

Query: 177 IFLFRR-----LKDIVDWRKDTRSSDDQKDDIPVENYVAQRYIENPYLIGGRKFDLRVYV 231
           IFLF R     + ++ D +++ +   DQ+     +++   + +EN + I  +K DL   +
Sbjct: 600 IFLFTRDFSRYISNMEDVKQELQQLRDQESKKNKDHFETLKNLENGFYINDQKADL--LL 657

Query: 232 LVMSVFAECLLWSGHRRQDVHLTNVAVQKTSPDYHPKKGCK-------WTLQRFRQYLAS 284
           L      E +L+  +  +       A+  TS D   +   +       W   +    +  
Sbjct: 658 LENKKLKEYILYLKNNIEKYREGQEALMHTSSDLSRQLIAQEAQYKDLWAEFQTTVKILV 717

Query: 285 KHGPEAVETLFRDIDNIFVKSLQSVQKV-IISDKHCFELYGYDILIDQDLKPWLLEVNAS 343
            +G E ++    DI+N+  K  +  +K+  +S      L G  +L++Q+    LL     
Sbjct: 718 DNGEETLQ----DINNLTDKLRERDEKMQHVSTWLRGSLEGLRLLVEQESPMDLLSKQQL 773

Query: 344 PSLTASSQEDYELKTCLLED 363
            +L  +S+E+   KTC L D
Sbjct: 774 RALLVTSKEE---KTCQLSD 790


>gi|169207046 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 828

 Score = 29.6 bits (65), Expect = 5.7
 Identities = 44/200 (22%), Positives = 86/200 (43%), Gaps = 22/200 (11%)

Query: 177 IFLFRR-----LKDIVDWRKDTRSSDDQKDDIPVENYVAQRYIENPYLIGGRKFDLRVYV 231
           IFLF R     + ++ D +++ +   DQ+     +++   + +EN + I  +K DL   +
Sbjct: 600 IFLFTRDFSRYISNMEDVKQELQQLRDQESKKNKDHFETLKNLENGFYINDQKADL--LL 657

Query: 232 LVMSVFAECLLWSGHRRQDVHLTNVAVQKTSPDYHPKKGCK-------WTLQRFRQYLAS 284
           L      E +L+  +  +       A+  TS D   +   +       W   +    +  
Sbjct: 658 LENKKLKEYILYLKNNIEKYREGQEALMHTSSDLSRQLIAQEAQYKDLWAEFQTTVKILV 717

Query: 285 KHGPEAVETLFRDIDNIFVKSLQSVQKV-IISDKHCFELYGYDILIDQDLKPWLLEVNAS 343
            +G E ++    DI+N+  K  +  +K+  +S      L G  +L++Q+    LL     
Sbjct: 718 DNGEETLQ----DINNLTDKLRERDEKMQHVSTWLRGSLEGLRLLVEQESPMDLLSKQQL 773

Query: 344 PSLTASSQEDYELKTCLLED 363
            +L  +S+E+   KTC L D
Sbjct: 774 RALLVTSKEE---KTCQLSD 790


>gi|21536346 T-cell leukemia/lymphoma 6 isoform TCL6d1 [Homo
           sapiens]
          Length = 163

 Score = 29.6 bits (65), Expect = 5.7
 Identities = 13/31 (41%), Positives = 18/31 (58%)

Query: 267 PKKGCKWTLQRFRQYLASKHGPEAVETLFRD 297
           PK+G +W   R + YL S+ G  A + L RD
Sbjct: 58  PKRGQQWLEARHKSYLHSRRGDHAKDKLQRD 88


>gi|155722987 elongation factor, RNA polymerase II, 2 [Homo sapiens]
          Length = 640

 Score = 29.6 bits (65), Expect = 5.7
 Identities = 12/46 (26%), Positives = 24/46 (52%)

Query: 9   LGPGTTAIRCPKKLQNQNYKGHGLSKGKEREQRASIRFKTTLMNTL 54
           L PG+  ++CPK ++  +   H  SK K ++ +   + K   + T+
Sbjct: 438 LPPGSVLLKCPKPMEENHSMSHKKSKKKSKKHKEKDQIKKHDIETI 483


>gi|169207319 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 828

 Score = 29.3 bits (64), Expect = 7.4
 Identities = 44/200 (22%), Positives = 86/200 (43%), Gaps = 22/200 (11%)

Query: 177 IFLFRR-----LKDIVDWRKDTRSSDDQKDDIPVENYVAQRYIENPYLIGGRKFDLRVYV 231
           IFLF R     + ++ D +++ +   DQ+     +++   + +EN + I  +K DL   +
Sbjct: 600 IFLFTRDFSRYISNMEDVKQELQQLRDQESKKNKDHFETLKNLENGFYINDQKADL--LL 657

Query: 232 LVMSVFAECLLWSGHRRQDVHLTNVAVQKTSPDYHPKKGCK-------WTLQRFRQYLAS 284
           L      E +L+  +  +       A+  TS D   +   +       W   +    +  
Sbjct: 658 LENKKLKEYILYLKNNIEKYREGQEALMHTSNDLSRQLIAQEAQYKDLWAEFQTTVKILV 717

Query: 285 KHGPEAVETLFRDIDNIFVKSLQSVQKV-IISDKHCFELYGYDILIDQDLKPWLLEVNAS 343
            +G E ++    DI+N+  K  +  +K+  +S      L G  +L++Q+    LL     
Sbjct: 718 DNGEETLQ----DINNLTDKLRERDEKMQHVSTWLRGSLEGLRLLVEQESPMDLLSKQQL 773

Query: 344 PSLTASSQEDYELKTCLLED 363
            +L  +S+E+   KTC L D
Sbjct: 774 RALLVTSKEE---KTCQLSD 790


>gi|110347451 platelet/endothelial cell adhesion molecule [Homo
           sapiens]
          Length = 738

 Score = 28.9 bits (63), Expect = 9.7
 Identities = 31/129 (24%), Positives = 53/129 (41%), Gaps = 10/129 (7%)

Query: 234 MSVFAECLLWSGHRRQDVHLT-NVAVQKTSPDYHPKKGCKWTLQRFRQYLASKHGPEAVE 292
           + V    LL S    Q+   T N    K+ PD+  + G   TLQ F     + H     +
Sbjct: 13  LGVLLTLLLCSSLEGQENSFTINSVDMKSLPDWTVQNGKNLTLQCFADVSTTSHVKPQHQ 72

Query: 293 TLFRDIDNIF--VKSLQSVQKVIISDKHCFE--LYGYDILIDQDLK-----PWLLEVNAS 343
            LF   D +F  + S++S +   I +   ++   Y   ++++   K       L+E   S
Sbjct: 73  MLFYKDDVLFYNISSMKSTESYFIPEVRIYDSGTYKCTVIVNNKEKTTAEYQLLVEGVPS 132

Query: 344 PSLTASSQE 352
           P +T   +E
Sbjct: 133 PRVTLDKKE 141


>gi|118918407 spectrin repeat containing, nuclear envelope 2 isoform 5
            [Homo sapiens]
          Length = 6907

 Score = 28.9 bits (63), Expect = 9.7
 Identities = 28/142 (19%), Positives = 58/142 (40%), Gaps = 4/142 (2%)

Query: 298  IDNIFVKSLQSVQKVIISDKHCFELYGYDILIDQDLKPWLLEVNASPSL--TASSQEDYE 355
            +++  +  ++ VQK +  + +C  L G    + +DL     ++  + SL    S  +  E
Sbjct: 1719 MESSILNKMEHVQKCLTGESNCHALSGSTAELREDLDQAKTQIGMTESLLKALSPSDSLE 1778

Query: 356  LKTCLLEDTLHVVDMEARLTGREKRVGGFDLMWNDGPVSREEGAPDLSGMGNFVTNTHLG 415
            + T L E    ++  +  +   E ++G      ++    + E   DL      V   H  
Sbjct: 1779 IFTKLEEIQQQILQQKHSMILLENQIGCLTPELSE-LKKQYESVSDLFNTKKSVLQDHFS 1837

Query: 416  -CVNDRKKQLRQLFCSLQVQKK 436
              +ND+ K     F +++V  K
Sbjct: 1838 KLLNDQCKNFNDWFSNIKVNLK 1859


>gi|118918403 spectrin repeat containing, nuclear envelope 2 isoform 1
            [Homo sapiens]
          Length = 6885

 Score = 28.9 bits (63), Expect = 9.7
 Identities = 28/142 (19%), Positives = 58/142 (40%), Gaps = 4/142 (2%)

Query: 298  IDNIFVKSLQSVQKVIISDKHCFELYGYDILIDQDLKPWLLEVNASPSL--TASSQEDYE 355
            +++  +  ++ VQK +  + +C  L G    + +DL     ++  + SL    S  +  E
Sbjct: 1719 MESSILNKMEHVQKCLTGESNCHALSGSTAELREDLDQAKTQIGMTESLLKALSPSDSLE 1778

Query: 356  LKTCLLEDTLHVVDMEARLTGREKRVGGFDLMWNDGPVSREEGAPDLSGMGNFVTNTHLG 415
            + T L E    ++  +  +   E ++G      ++    + E   DL      V   H  
Sbjct: 1779 IFTKLEEIQQQILQQKHSMILLENQIGCLTPELSE-LKKQYESVSDLFNTKKSVLQDHFS 1837

Query: 416  -CVNDRKKQLRQLFCSLQVQKK 436
              +ND+ K     F +++V  K
Sbjct: 1838 KLLNDQCKNFNDWFSNIKVNLK 1859


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.137    0.429 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,128,480
Number of Sequences: 37866
Number of extensions: 744102
Number of successful extensions: 1679
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1613
Number of HSP's gapped (non-prelim): 32
length of query: 439
length of database: 18,247,518
effective HSP length: 105
effective length of query: 334
effective length of database: 14,271,588
effective search space: 4766710392
effective search space used: 4766710392
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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