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Search of human proteins with 56549653
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|56549653 neuro-oncological ventral antigen 1 isoform 1 [Homo
sapiens]
(507 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|56549653 neuro-oncological ventral antigen 1 isoform 1 [Homo ... 978 0.0
gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo ... 917 0.0
gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens] 669 0.0
gi|6031189 neuro-oncological ventral antigen 1 isoform 3 [Homo s... 346 3e-95
gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens] 104 2e-22
gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens] 102 6e-22
gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens] 102 1e-21
gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens] 100 4e-21
gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens] 87 5e-17
gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens] 86 6e-17
gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens] 86 6e-17
gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens] 86 1e-16
gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens] 85 1e-16
gi|222352151 poly(rC) binding protein 1 [Homo sapiens] 82 1e-15
gi|14670373 poly(rC) binding protein 4 isoform c [Homo sapiens] 76 8e-14
gi|14670369 poly(rC) binding protein 4 isoform c [Homo sapiens] 76 8e-14
gi|56118219 insulin-like growth factor 2 mRNA binding protein 2 ... 74 3e-13
gi|64085377 insulin-like growth factor 2 mRNA binding protein 2 ... 73 7e-13
gi|30795212 insulin-like growth factor 2 mRNA binding protein 3 ... 71 3e-12
gi|238624257 insulin-like growth factor 2 mRNA binding protein 1... 69 1e-11
gi|56237027 insulin-like growth factor 2 mRNA binding protein 1 ... 67 4e-11
gi|17402900 far upstream element-binding protein [Homo sapiens] 67 5e-11
gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a ... 64 4e-10
gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b ... 64 4e-10
gi|14165437 heterogeneous nuclear ribonucleoprotein K isoform a ... 64 4e-10
gi|145312259 tudor and KH domain containing isoform a [Homo sapi... 63 6e-10
gi|145312270 tudor and KH domain containing isoform a [Homo sapi... 63 6e-10
gi|145312256 tudor and KH domain containing isoform a [Homo sapi... 63 6e-10
gi|100816392 far upstream element (FUSE) binding protein 3 [Homo... 61 2e-09
gi|9966803 poly(rC) binding protein 4 isoform a [Homo sapiens] 58 2e-08
>gi|56549653 neuro-oncological ventral antigen 1 isoform 1 [Homo
sapiens]
Length = 507
Score = 978 bits (2527), Expect = 0.0
Identities = 507/507 (100%), Positives = 507/507 (100%)
Query: 1 MMAAAPIQQNGTHTGVPIDLDPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYA 60
MMAAAPIQQNGTHTGVPIDLDPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYA
Sbjct: 1 MMAAAPIQQNGTHTGVPIDLDPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYA 60
Query: 61 AGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKI 120
AGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKI
Sbjct: 61 AGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKI 120
Query: 121 REMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTTSRANQVKIIVPN 180
REMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTTSRANQVKIIVPN
Sbjct: 121 REMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTTSRANQVKIIVPN 180
Query: 181 STAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQK 240
STAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQK
Sbjct: 181 STAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQK 240
Query: 241 IQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHANLAGVAAF 300
IQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHANLAGVAAF
Sbjct: 241 IQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHANLAGVAAF 300
Query: 301 PAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAASANPAAAAAN 360
PAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAASANPAAAAAN
Sbjct: 301 PAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAASANPAAAAAN 360
Query: 361 LLATYASEASASGSTAGGTAGTFALGSLAAATAATNGYFGAASPLAASAILGTEKSTDGS 420
LLATYASEASASGSTAGGTAGTFALGSLAAATAATNGYFGAASPLAASAILGTEKSTDGS
Sbjct: 361 LLATYASEASASGSTAGGTAGTFALGSLAAATAATNGYFGAASPLAASAILGTEKSTDGS 420
Query: 421 KDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAA 480
KDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAA
Sbjct: 421 KDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAA 480
Query: 481 TQAAQYLITQRITYEQGVRAANPQKVG 507
TQAAQYLITQRITYEQGVRAANPQKVG
Sbjct: 481 TQAAQYLITQRITYEQGVRAANPQKVG 507
>gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo
sapiens]
Length = 483
Score = 917 bits (2370), Expect = 0.0
Identities = 483/507 (95%), Positives = 483/507 (95%), Gaps = 24/507 (4%)
Query: 1 MMAAAPIQQNGTHTGVPIDLDPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYA 60
MMAAAPIQQNGTHTGVPIDLDPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYA
Sbjct: 1 MMAAAPIQQNGTHTGVPIDLDPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYA 60
Query: 61 AGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKI 120
AGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKI
Sbjct: 61 AGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKI 120
Query: 121 REMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTTSRANQVKIIVPN 180
REMPQNVAKTEPVSILQPQTTVNPDRIKQ VKIIVPN
Sbjct: 121 REMPQNVAKTEPVSILQPQTTVNPDRIKQ------------------------VKIIVPN 156
Query: 181 STAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQK 240
STAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQK
Sbjct: 157 STAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQK 216
Query: 241 IQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHANLAGVAAF 300
IQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHANLAGVAAF
Sbjct: 217 IQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHANLAGVAAF 276
Query: 301 PAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAASANPAAAAAN 360
PAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAASANPAAAAAN
Sbjct: 277 PAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAASANPAAAAAN 336
Query: 361 LLATYASEASASGSTAGGTAGTFALGSLAAATAATNGYFGAASPLAASAILGTEKSTDGS 420
LLATYASEASASGSTAGGTAGTFALGSLAAATAATNGYFGAASPLAASAILGTEKSTDGS
Sbjct: 337 LLATYASEASASGSTAGGTAGTFALGSLAAATAATNGYFGAASPLAASAILGTEKSTDGS 396
Query: 421 KDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAA 480
KDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAA
Sbjct: 397 KDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAA 456
Query: 481 TQAAQYLITQRITYEQGVRAANPQKVG 507
TQAAQYLITQRITYEQGVRAANPQKVG
Sbjct: 457 TQAAQYLITQRITYEQGVRAANPQKVG 483
>gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens]
Length = 492
Score = 669 bits (1726), Expect = 0.0
Identities = 370/516 (71%), Positives = 409/516 (79%), Gaps = 56/516 (10%)
Query: 21 DPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETG 80
+ PDSRKRPLE PPE TKR+NTGE+G+YFLKVLIPSYAAGSIIGKGGQTIVQLQKETG
Sbjct: 4 EAPDSRKRPLETPPEVVCTKRSNTGEEGEYFLKVLIPSYAAGSIIGKGGQTIVQLQKETG 63
Query: 81 ATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQT 140
ATIKLSKSKDFYPGTTERVCL+QGT EALNAVH FIAEK+RE+PQ + K E V+ILQPQT
Sbjct: 64 ATIKLSKSKDFYPGTTERVCLVQGTAEALNAVHSFIAEKVREIPQAMTKPEVVNILQPQT 123
Query: 141 TVNPDRIKQTLPSSPTTTKSSPSDPMTTSRANQVKIIVPNSTAGLIIGKGGATVKAVMEQ 200
T+NPD RA Q K+IVPNSTAGLIIGKGGATVKAVMEQ
Sbjct: 124 TMNPD------------------------RAKQAKLIVPNSTAGLIIGKGGATVKAVMEQ 159
Query: 201 SGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSGSCLNISYANVTG 260
SGAWVQLSQKP+GINLQERVVTVSGEPEQ KAV I+QK+QEDPQS SCLNISYANV G
Sbjct: 160 SGAWVQLSQKPEGINLQERVVTVSGEPEQVHKAVSAIVQKVQEDPQSSSCLNISYANVAG 219
Query: 261 PVANSNPTGSPYANTAEVLP-----TAAAAAGLLGHANLAGVAAFPAVLSGFTGNDLVAI 315
PVANSNPTGSPYA+ A+VLP +AAAA+GLLG A LAGV AFPA L F+G DL+AI
Sbjct: 220 PVANSNPTGSPYASPADVLPAAAAASAAAASGLLGPAGLAGVGAFPAALPAFSGTDLLAI 279
Query: 316 TSALNTLASYGYNLNTLGLGLSQAAATGALAAAAASANP-AAAAANLLATYASEASASGS 374
++ALNTLASYGYN N+LGLGL+ AAA+G LAA AA ANP AAAAANLLA+YA EA A
Sbjct: 280 STALNTLASYGYNTNSLGLGLNSAAASGVLAAVAAGANPAAAAAANLLASYAGEAGA--G 337
Query: 375 TAGGTA-----GTFALGSLAAATAATNGYFGAAS---------PLAASA--------ILG 412
AGG A ALGS A A AA NGY GA + PL A+A L
Sbjct: 338 PAGGAAPPPPPPPGALGSFALA-AAANGYLGAGAGGGAGGGGGPLVAAAAAAGAAGGFLT 396
Query: 413 TEK-STDGSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRK 471
EK + + +K++VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEF+PGTRNR+
Sbjct: 397 AEKLAAESAKELVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRR 456
Query: 472 VTITGTPAATQAAQYLITQRITYEQGVRAANPQKVG 507
VTITG+PAATQAAQYLI+QR+TYEQGVRA+NPQKVG
Sbjct: 457 VTITGSPAATQAAQYLISQRVTYEQGVRASNPQKVG 492
>gi|6031189 neuro-oncological ventral antigen 1 isoform 3 [Homo
sapiens]
Length = 181
Score = 346 bits (887), Expect = 3e-95
Identities = 173/173 (100%), Positives = 173/173 (100%)
Query: 1 MMAAAPIQQNGTHTGVPIDLDPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYA 60
MMAAAPIQQNGTHTGVPIDLDPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYA
Sbjct: 1 MMAAAPIQQNGTHTGVPIDLDPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYA 60
Query: 61 AGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKI 120
AGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKI
Sbjct: 61 AGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKI 120
Query: 121 REMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTTSRANQ 173
REMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTTSRANQ
Sbjct: 121 REMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTTSRANQ 173
Score = 65.1 bits (157), Expect = 1e-10
Identities = 35/92 (38%), Positives = 53/92 (57%), Gaps = 3/92 (3%)
Query: 404 PLAASAILGTEKSTDGSKD---VVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKK 460
PL A G+ K T+ +D +++ +P G+I+GKGG+T+V+ Q+ TGA I++SK
Sbjct: 29 PLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKS 88
Query: 461 GEFVPGTRNRKVTITGTPAATQAAQYLITQRI 492
+F PGT R I GT A A I ++I
Sbjct: 89 KDFYPGTTERVCLIQGTVEALNAVHGFIAEKI 120
Score = 53.1 bits (126), Expect = 6e-07
Identities = 33/104 (31%), Positives = 53/104 (50%), Gaps = 8/104 (7%)
Query: 152 PSSPTTTKSSPSDPMTTSRANQ-------VKIIVPNSTAGLIIGKGGATVKAVMEQSGAW 204
P S +P + +T R N +K+++P+ AG IIGKGG T+ + +++GA
Sbjct: 23 PDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGAT 82
Query: 205 VQLSQKPDGI-NLQERVVTVSGEPEQNRKAVELIIQKIQEDPQS 247
++LS+ D ERV + G E I +KI+E PQ+
Sbjct: 83 IKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQN 126
>gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens]
Length = 361
Score = 104 bits (260), Expect = 2e-22
Identities = 111/448 (24%), Positives = 188/448 (41%), Gaps = 109/448 (24%)
Query: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
+++L+ GSIIGK G+++ ++++E+GA I +S+ ER+ + G A+
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEG-----NCPERIITLAGPTNAIFK 70
Query: 112 VHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTTSRA 171
I +K+ E + SS T + ++ P+T
Sbjct: 71 AFAMIIDKLEE---------------------------DISSSMTNSTAASRPPVT---- 99
Query: 172 NQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLS--QKPDGINLQERVVTVSGEPEQ 229
++++VP S G +IGKGG +K + E +GA VQ++ P N ER +T++G P+
Sbjct: 100 --LRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLP---NSTERAITIAGIPQS 154
Query: 230 NRKAVELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLL 289
+ V+ I + E P G + I Y P+ SP A G
Sbjct: 155 IIECVKQICVVMLESPPKG--VTIPY--------RPKPSSSP----------VIFAGGQD 194
Query: 290 GHANLAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAA 349
++ + A+FP +T S N + G L G A
Sbjct: 195 RYSTGSDSASFP------------------HTTPSMCLNPDLEGPPLEAYTIQGQYAI-- 234
Query: 350 ASANPAAAAANLLATYASEASASGSTAGGTAGTFALGSLAAATAATNGYFGAASPLAASA 409
P + LA S T G + +++ GY+G L ASA
Sbjct: 235 --PQPDLTKLHQLAMQQSHFPM-------THGNTGFSGIESSSPEVKGYWG----LDASA 281
Query: 410 ILGTEKSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRN 469
+ E+ +P +L+G I+G+ G + E ++++GA+I+I+ V G+ +
Sbjct: 282 QTTSH----------ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANP---VEGSTD 328
Query: 470 RKVTITGTPAATQAAQYLITQRITYEQG 497
R+VTITG+ A+ AQYLI R++ E G
Sbjct: 329 RQVTITGSAASISLAQYLINVRLSSETG 356
>gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens]
Length = 362
Score = 102 bits (255), Expect = 6e-22
Identities = 110/448 (24%), Positives = 187/448 (41%), Gaps = 108/448 (24%)
Query: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
+++L+ GSIIGK G+++ ++++E+GA I +S+ ER+ + G A+
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEG-----NCPERIITLAGPTNAIFK 70
Query: 112 VHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTTSRA 171
I +K+ E + SS T + ++ P+T
Sbjct: 71 AFAMIIDKLEE---------------------------DISSSMTNSTAASRPPVT---- 99
Query: 172 NQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLS--QKPDGINLQERVVTVSGEPEQ 229
++++VP S G +IGKGG +K + E +GA VQ++ P N ER +T++G P+
Sbjct: 100 --LRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLP---NSTERAITIAGIPQS 154
Query: 230 NRKAVELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLL 289
+ V+ I + E P G + I Y P+ SP A G
Sbjct: 155 IIECVKQICVVMLESPPKG--VTIPY--------RPKPSSSP----------VIFAGGQD 194
Query: 290 GHANLAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAA 349
++ + A+FP +T S N + G L G A
Sbjct: 195 RYSTGSDSASFP------------------HTTPSMCLNPDLEGPPLEAYTIQGQYAI-- 234
Query: 350 ASANPAAAAANLLATYASEASASGSTAGGTAGTFALGSLAAATAATNGYFGAASPLAASA 409
P + LA S T G + +++ GY+ L ASA
Sbjct: 235 --PQPDLTKLHQLAMQQSHFPM-------THGNTGFSGIESSSPEVKGYWAG---LDASA 282
Query: 410 ILGTEKSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRN 469
+ E+ +P +L+G I+G+ G + E ++++GA+I+I+ V G+ +
Sbjct: 283 QTTSH----------ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANP---VEGSTD 329
Query: 470 RKVTITGTPAATQAAQYLITQRITYEQG 497
R+VTITG+ A+ AQYLI R++ E G
Sbjct: 330 RQVTITGSAASISLAQYLINVRLSSETG 357
>gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens]
Length = 365
Score = 102 bits (253), Expect = 1e-21
Identities = 109/452 (24%), Positives = 191/452 (42%), Gaps = 113/452 (25%)
Query: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
+++L+ GSIIGK G+++ ++++E+GA I +S+ ER+ + G A+
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEG-----NCPERIITLAGPTNAIFK 70
Query: 112 VHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTTSRA 171
I +K+ E + SS T + ++ P+T
Sbjct: 71 AFAMIIDKLEE---------------------------DISSSMTNSTAASRPPVT---- 99
Query: 172 NQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLS--QKPDGINLQERVVTVSGEPEQ 229
++++VP S G +IGKGG +K + E +GA VQ++ P N ER +T++G P+
Sbjct: 100 --LRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLP---NSTERAITIAGIPQS 154
Query: 230 NRKAVE----LIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAA 285
+ V+ ++++ + + P G + I Y P+ SP A
Sbjct: 155 IIECVKQICVVMLETLSQSPPKG--VTIPY--------RPKPSSSP----------VIFA 194
Query: 286 AGLLGHANLAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGAL 345
G ++ + A+FP +T S N + G L G
Sbjct: 195 GGQDRYSTGSDSASFP------------------HTTPSMCLNPDLEGPPLEAYTIQGQY 236
Query: 346 AAAAASANPAAAAANLLATYASEASASGSTAGGTAGTFALGSLAAATAATNGYFGAASPL 405
A P + LA S T G + +++ GY+G L
Sbjct: 237 AI----PQPDLTKLHQLAMQQSHFPM-------THGNTGFSGIESSSPEVKGYWG----L 281
Query: 406 AASAILGTEKSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVP 465
ASA + E+ +P +L+G I+G+ G + E ++++GA+I+I+ V
Sbjct: 282 DASAQTTSH----------ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANP---VE 328
Query: 466 GTRNRKVTITGTPAATQAAQYLITQRITYEQG 497
G+ +R+VTITG+ A+ AQYLI R++ E G
Sbjct: 329 GSTDRQVTITGSAASISLAQYLINVRLSSETG 360
>gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens]
Length = 366
Score = 100 bits (248), Expect = 4e-21
Identities = 108/452 (23%), Positives = 190/452 (42%), Gaps = 112/452 (24%)
Query: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
+++L+ GSIIGK G+++ ++++E+GA I +S+ ER+ + G A+
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEG-----NCPERIITLAGPTNAIFK 70
Query: 112 VHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTTSRA 171
I +K+ E + SS T + ++ P+T
Sbjct: 71 AFAMIIDKLEE---------------------------DISSSMTNSTAASRPPVT---- 99
Query: 172 NQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLS--QKPDGINLQERVVTVSGEPEQ 229
++++VP S G +IGKGG +K + E +GA VQ++ P N ER +T++G P+
Sbjct: 100 --LRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLP---NSTERAITIAGIPQS 154
Query: 230 NRKAVE----LIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAA 285
+ V+ ++++ + + P G + I Y P+ SP A
Sbjct: 155 IIECVKQICVVMLETLSQSPPKG--VTIPY--------RPKPSSSP----------VIFA 194
Query: 286 AGLLGHANLAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGAL 345
G ++ + A+FP +T S N + G L G
Sbjct: 195 GGQDRYSTGSDSASFP------------------HTTPSMCLNPDLEGPPLEAYTIQGQY 236
Query: 346 AAAAASANPAAAAANLLATYASEASASGSTAGGTAGTFALGSLAAATAATNGYFGAASPL 405
A P + LA S T G + +++ GY+ L
Sbjct: 237 AI----PQPDLTKLHQLAMQQSHFPM-------THGNTGFSGIESSSPEVKGYWAG---L 282
Query: 406 AASAILGTEKSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVP 465
ASA + E+ +P +L+G I+G+ G + E ++++GA+I+I+ V
Sbjct: 283 DASAQTTSH----------ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANP---VE 329
Query: 466 GTRNRKVTITGTPAATQAAQYLITQRITYEQG 497
G+ +R+VTITG+ A+ AQYLI R++ E G
Sbjct: 330 GSTDRQVTITGSAASISLAQYLINVRLSSETG 361
>gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens]
Length = 318
Score = 86.7 bits (213), Expect = 5e-17
Identities = 80/329 (24%), Positives = 143/329 (43%), Gaps = 36/329 (10%)
Query: 174 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 233
+++++ G IIGK G +VK + E+SGA + +S+ N ER++T++G KA
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEG----NCPERIITLAGPTNAIFKA 71
Query: 234 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHAN 293
+II K++ED ++ + NS P V+P A+ L+G
Sbjct: 72 FAMIIDKLEED-------------ISSSMTNSTAASRPPVTLRLVVP-ASQCGSLIGKGG 117
Query: 294 --LAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAAS 351
+ + G+ L T T+A ++ +
Sbjct: 118 CKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIP 177
Query: 352 ANPAAAAANLLATYASEASASGSTAGGTAGTFALGSLAAATA---ATNGYFGAASPLAAS 408
P +++ ++ + G A L LA + T+G G ++ L AS
Sbjct: 178 YRPKPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSAGLDAS 237
Query: 409 AILGTEKSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTR 468
A + E+ +P +L+G I+G+ G + E ++++GA+I+I+ V G+
Sbjct: 238 AQTTSH----------ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANP---VEGST 284
Query: 469 NRKVTITGTPAATQAAQYLITQRITYEQG 497
+R+VTITG+ A+ AQYLI R++ E G
Sbjct: 285 DRQVTITGSAASISLAQYLINVRLSSETG 313
Score = 70.9 bits (172), Expect = 3e-12
Identities = 52/199 (26%), Positives = 93/199 (46%), Gaps = 43/199 (21%)
Query: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
+++L+ GSIIGK G+++ ++++E+GA I +S+ ER+ + G A+
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEG-----NCPERIITLAGPTNAIFK 70
Query: 112 VHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTTSRA 171
I +K+ E + SS T + ++ P+T
Sbjct: 71 AFAMIIDKLEE---------------------------DISSSMTNSTAASRPPVT---- 99
Query: 172 NQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLS--QKPDGINLQERVVTVSGEPEQ 229
++++VP S G +IGKGG +K + E +GA VQ++ P N ER +T++G P+
Sbjct: 100 --LRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLP---NSTERAITIAGIPQS 154
Query: 230 NRKAVELIIQKIQEDPQSG 248
+ V+ I + E P G
Sbjct: 155 IIECVKQICVVMLESPPKG 173
Score = 32.0 bits (71), Expect = 1.4
Identities = 17/58 (29%), Positives = 35/58 (60%), Gaps = 3/58 (5%)
Query: 53 KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALN 110
++ IP+ G IIG+ G I ++++ +GA IK++ + G+T+R I G+ +++
Sbjct: 244 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE---GSTDRQVTITGSAASIS 298
>gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens]
Length = 331
Score = 86.3 bits (212), Expect = 6e-17
Identities = 80/334 (23%), Positives = 142/334 (42%), Gaps = 33/334 (9%)
Query: 174 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 233
+++++ G IIGK G +VK + E+SGA + +S+ N ER++T++G KA
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEG----NCPERIITLAGPTNAIFKA 71
Query: 234 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHAN 293
+II K++ED ++ + NS P V+P A+ L+G
Sbjct: 72 FAMIIDKLEED-------------ISSSMTNSTAASRPPVTLRLVVP-ASQCGSLIGKGG 117
Query: 294 --LAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAAS 351
+ + G+ L T T+A ++ +
Sbjct: 118 CKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIP 177
Query: 352 ANPAAAAANLLATYASEASASGSTAGGTAGTFALGSLAAA------TAATNGYFGAASPL 405
P +++ ++ + G A L LA T G+ G S
Sbjct: 178 YRPKPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIES-- 235
Query: 406 AASAILGTEKSTDGSKDVV--EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEF 463
++ + G D S E+ +P +L+G I+G+ G + E ++++GA+I+I+
Sbjct: 236 SSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANP--- 292
Query: 464 VPGTRNRKVTITGTPAATQAAQYLITQRITYEQG 497
V G+ +R+VTITG+ A+ AQYLI R++ E G
Sbjct: 293 VEGSTDRQVTITGSAASISLAQYLINVRLSSETG 326
Score = 70.9 bits (172), Expect = 3e-12
Identities = 52/199 (26%), Positives = 93/199 (46%), Gaps = 43/199 (21%)
Query: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
+++L+ GSIIGK G+++ ++++E+GA I +S+ ER+ + G A+
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEG-----NCPERIITLAGPTNAIFK 70
Query: 112 VHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTTSRA 171
I +K+ E + SS T + ++ P+T
Sbjct: 71 AFAMIIDKLEE---------------------------DISSSMTNSTAASRPPVT---- 99
Query: 172 NQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLS--QKPDGINLQERVVTVSGEPEQ 229
++++VP S G +IGKGG +K + E +GA VQ++ P N ER +T++G P+
Sbjct: 100 --LRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLP---NSTERAITIAGIPQS 154
Query: 230 NRKAVELIIQKIQEDPQSG 248
+ V+ I + E P G
Sbjct: 155 IIECVKQICVVMLESPPKG 173
Score = 32.0 bits (71), Expect = 1.4
Identities = 17/58 (29%), Positives = 35/58 (60%), Gaps = 3/58 (5%)
Query: 53 KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALN 110
++ IP+ G IIG+ G I ++++ +GA IK++ + G+T+R I G+ +++
Sbjct: 257 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE---GSTDRQVTITGSAASIS 311
>gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens]
Length = 345
Score = 86.3 bits (212), Expect = 6e-17
Identities = 86/328 (26%), Positives = 140/328 (42%), Gaps = 43/328 (13%)
Query: 174 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 233
+++++ G IIGK G TVK + E+SGA + +S+ N ER+VT++G + KA
Sbjct: 48 IRLLMHGKEVGSIIGKKGETVKKMREESGARINISEG----NCPERIVTITGPTDAIFKA 103
Query: 234 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHAN 293
+I K +ED + ++NS T P V+P A+ L+G
Sbjct: 104 FAMIAYKFEED-------------IINSMSNSPATSKPPVTLRLVVP-ASQCGSLIGKGG 149
Query: 294 LA------GVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAA 347
A V N + T + + + + + +A +
Sbjct: 150 SKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLEAYT---IQG 206
Query: 348 AAASANPAAAAANLLATYASEASASGSTAGGTAGTFALGSLAAATAATNGYFGAASPLAA 407
A +P + LA + G T G L ++ A N G +S L A
Sbjct: 207 QYAIPHPDLTKLHQLAMQQTPFPPLGQTNPAFPGEKL--PLHSSEEAQN-LMGQSSGLDA 263
Query: 408 SAILGTEKSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGT 467
S T E+ +P +L+G I+G+ G + E ++++GA+I+I+ E G+
Sbjct: 264 SPPASTH----------ELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATE---GS 310
Query: 468 RNRKVTITGTPAATQAAQYLITQRITYE 495
R++TITGTPA AQYLI R+T E
Sbjct: 311 SERQITITGTPANISLAQYLINARLTSE 338
Score = 73.6 bits (179), Expect = 4e-13
Identities = 60/209 (28%), Positives = 98/209 (46%), Gaps = 46/209 (22%)
Query: 34 PEAGSTKRTNTGEDG---QYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKD 90
P+ G + E G +++L+ GSIIGK G+T+ ++++E+GA I +S+
Sbjct: 27 PQFGRRMESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGN- 85
Query: 91 FYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQT 150
ER+ I G +A+ IA K E I +
Sbjct: 86 ----CPERIVTITGPTDAIFKAFAMIAYKFEE-----------------------DIINS 118
Query: 151 LPSSPTTTKSSPSDPMTTSRANQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLS-- 208
+ +SP T+K P+T ++++VP S G +IGKGG+ +K + E +GA VQ++
Sbjct: 119 MSNSPATSKP----PVT------LRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGD 168
Query: 209 QKPDGINLQERVVTVSGEPEQNRKAVELI 237
P N ER VT+SG P+ + V+ I
Sbjct: 169 MLP---NSTERAVTISGTPDAIIQCVKQI 194
Score = 67.8 bits (164), Expect = 2e-11
Identities = 53/211 (25%), Positives = 101/211 (47%), Gaps = 22/211 (10%)
Query: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
L++++P+ GS+IGKGG I ++++ TGA ++++ D P +TER I GT +A+
Sbjct: 132 LRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAG--DMLPNSTERAVTISGTPDAIIQ 189
Query: 112 ---------VHGFIAEKIREMPQ-NVAKTEPVSILQ----PQTTVNPDRIKQTLP---SS 154
+ + + +P ++ K +++ Q P NP + LP S
Sbjct: 190 CVKQICVVMLEAYTIQGQYAIPHPDLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSE 249
Query: 155 PTTTKSSPSDPMTTSR-ANQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDG 213
S + S A+ ++ +PN G IIG+ G + + + SGA ++++ +G
Sbjct: 250 EAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEG 309
Query: 214 INLQERVVTVSGEPEQNRKAVELIIQKIQED 244
+ ER +T++G P A LI ++ +
Sbjct: 310 SS--ERQITITGTPANISLAQYLINARLTSE 338
>gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens]
Length = 335
Score = 85.5 bits (210), Expect = 1e-16
Identities = 80/338 (23%), Positives = 146/338 (43%), Gaps = 37/338 (10%)
Query: 174 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 233
+++++ G IIGK G +VK + E+SGA + +S+ N ER++T++G KA
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEG----NCPERIITLAGPTNAIFKA 71
Query: 234 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHAN 293
+II K++ED ++ + NS P V+P A+ L+G
Sbjct: 72 FAMIIDKLEED-------------ISSSMTNSTAASRPPVTLRLVVP-ASQCGSLIGKGG 117
Query: 294 --LAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNL----NTLGLGLSQAAATGALAA 347
+ + G+ L T T+A ++ + + + + +
Sbjct: 118 CKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKG 177
Query: 348 AAASANPAAAAANLLATYASEASASGSTAGGTAGTFALGSLAAA------TAATNGYFGA 401
P +++ ++ + G A L LA T G+ G
Sbjct: 178 VTIPYRPKPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGI 237
Query: 402 ASPLAASAILGTEKSTDGSKDVV--EIAVPENLVGAILGKGGKTLVEYQELTGARIQISK 459
S ++ + G D S E+ +P +L+G I+G+ G + E ++++GA+I+I+
Sbjct: 238 ES--SSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIAN 295
Query: 460 KGEFVPGTRNRKVTITGTPAATQAAQYLITQRITYEQG 497
V G+ +R+VTITG+ A+ AQYLI R++ E G
Sbjct: 296 P---VEGSTDRQVTITGSAASISLAQYLINVRLSSETG 330
Score = 68.2 bits (165), Expect = 2e-11
Identities = 50/203 (24%), Positives = 96/203 (47%), Gaps = 47/203 (23%)
Query: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
+++L+ GSIIGK G+++ ++++E+GA I +S+ ER+ + G A+
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEG-----NCPERIITLAGPTNAIFK 70
Query: 112 VHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTTSRA 171
I +K+ E + SS T + ++ P+T
Sbjct: 71 AFAMIIDKLEE---------------------------DISSSMTNSTAASRPPVT---- 99
Query: 172 NQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLS--QKPDGINLQERVVTVSGEPEQ 229
++++VP S G +IGKGG +K + E +GA VQ++ P N ER +T++G P+
Sbjct: 100 --LRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLP---NSTERAITIAGIPQS 154
Query: 230 NRKAVE----LIIQKIQEDPQSG 248
+ V+ ++++ + + P G
Sbjct: 155 IIECVKQICVVMLETLSQSPPKG 177
Score = 32.0 bits (71), Expect = 1.4
Identities = 17/58 (29%), Positives = 35/58 (60%), Gaps = 3/58 (5%)
Query: 53 KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALN 110
++ IP+ G IIG+ G I ++++ +GA IK++ + G+T+R I G+ +++
Sbjct: 261 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE---GSTDRQVTITGSAASIS 315
>gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens]
Length = 371
Score = 85.1 bits (209), Expect = 1e-16
Identities = 85/337 (25%), Positives = 141/337 (41%), Gaps = 35/337 (10%)
Query: 174 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 233
+++++ G IIGK G TVK + E+SGA + +S+ N ER+VT++G + KA
Sbjct: 48 IRLLMHGKEVGSIIGKKGETVKKMREESGARINISEG----NCPERIVTITGPTDAIFKA 103
Query: 234 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGL-LGHA 292
+I K +ED + ++NS T P V+P + + + G +
Sbjct: 104 FAMIAYKFEED-------------IINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGS 150
Query: 293 NLAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAASA 352
+ + G+ L T T++ + + A
Sbjct: 151 KIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLESPPKGATIPY 210
Query: 353 NPAAAAANLLATYASEASASGSTAGGTAGTFA-LGSLAAATAA------TNGYF-GAASP 404
P A+ ++ + G A L LA TN F G P
Sbjct: 211 RPKPASTPVIFAGGQAYTIQGQYAIPHPDQLTKLHQLAMQQTPFPPLGQTNPAFPGEKLP 270
Query: 405 LAASA----ILGTEKSTDGSKDVV--EIAVPENLVGAILGKGGKTLVEYQELTGARIQIS 458
L +S ++G D S E+ +P +L+G I+G+ G + E ++++GA+I+I+
Sbjct: 271 LHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIA 330
Query: 459 KKGEFVPGTRNRKVTITGTPAATQAAQYLITQRITYE 495
E G+ R++TITGTPA AQYLI R+T E
Sbjct: 331 NATE---GSSERQITITGTPANISLAQYLINARLTSE 364
Score = 78.6 bits (192), Expect = 1e-14
Identities = 63/223 (28%), Positives = 104/223 (46%), Gaps = 46/223 (20%)
Query: 34 PEAGSTKRTNTGEDG---QYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKD 90
P+ G + E G +++L+ GSIIGK G+T+ ++++E+GA I +S+
Sbjct: 27 PQFGRRMESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGN- 85
Query: 91 FYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQT 150
ER+ I G +A+ IA K E I +
Sbjct: 86 ----CPERIVTITGPTDAIFKAFAMIAYKFEE-----------------------DIINS 118
Query: 151 LPSSPTTTKSSPSDPMTTSRANQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLS-- 208
+ +SP T+K P+T ++++VP S G +IGKGG+ +K + E +GA VQ++
Sbjct: 119 MSNSPATSKP----PVT------LRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGD 168
Query: 209 QKPDGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSGSCL 251
P N ER VT+SG P+ + V+ I + E P G+ +
Sbjct: 169 MLP---NSTERAVTISGTPDAIIQCVKQICVVMLESPPKGATI 208
Score = 65.5 bits (158), Expect = 1e-10
Identities = 59/237 (24%), Positives = 108/237 (45%), Gaps = 48/237 (20%)
Query: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
L++++P+ GS+IGKGG I ++++ TGA ++++ D P +TER I GT +A+
Sbjct: 132 LRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAG--DMLPNSTERAVTISGTPDAIIQ 189
Query: 112 VHGFIAEKIREMPQNVA----KTEPVSI-----------LQPQTTV-NPDRIK------- 148
I + E P A + +P S +Q Q + +PD++
Sbjct: 190 CVKQICVVMLESPPKGATIPYRPKPASTPVIFAGGQAYTIQGQYAIPHPDQLTKLHQLAM 249
Query: 149 QTLPSSPT--TTKSSPSD--PMTTSR-----------------ANQVKIIVPNSTAGLII 187
Q P P T + P + P+ +S A+ ++ +PN G II
Sbjct: 250 QQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCII 309
Query: 188 GKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQKIQED 244
G+ G + + + SGA ++++ +G + ER +T++G P A LI ++ +
Sbjct: 310 GRQGTKINEIRQMSGAQIKIANATEGSS--ERQITITGTPANISLAQYLINARLTSE 364
Score = 35.4 bits (80), Expect = 0.12
Identities = 25/82 (30%), Positives = 44/82 (53%), Gaps = 6/82 (7%)
Query: 27 KRPLEAPPEAGSTKRTNTGEDGQ---YFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATI 83
K PL + EA + ++G D ++ IP+ G IIG+ G I ++++ +GA I
Sbjct: 268 KLPLHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQI 327
Query: 84 KLSKSKDFYPGTTERVCLIQGT 105
K++ + + G++ER I GT
Sbjct: 328 KIANATE---GSSERQITITGT 346
>gi|222352151 poly(rC) binding protein 1 [Homo sapiens]
Length = 356
Score = 82.0 bits (201), Expect = 1e-15
Identities = 87/360 (24%), Positives = 147/360 (40%), Gaps = 57/360 (15%)
Query: 174 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 233
+++++ G IIGK G +VK + E+SGA + +S+ N ER++T++G KA
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKRIREESGARINISEG----NCPERIITLTGPTNAIFKA 71
Query: 234 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGL-LGHA 292
+II K++E ++ + NS P V+P + + G
Sbjct: 72 FAMIIDKLEE-------------DINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGC 118
Query: 293 NLAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYN------------LNTLG------- 333
+ + G+ L T T+A + L TL
Sbjct: 119 KIKEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRV 178
Query: 334 --LGLSQAAATGALAAAAASANPAAAAANLLATYASEA------SASGSTAGGTAGTFAL 385
+ A+ + A + AA AT+ E S G L
Sbjct: 179 MTIPYQPMPASSPVICAGGQDRCSDAAGYPHATHDLEGPPLDAYSIQGQHTISPLDLAKL 238
Query: 386 GSLA------AATAATNGYFGAASPLAASAILGTEKSTDGSKDVV-EIAVPENLVGAILG 438
+A A G+ G S ++ + G S D S E+ +P NL+G I+G
Sbjct: 239 NQVARQQSHFAMMHGGTGFAGIDS--SSPEVKGYWASLDASTQTTHELTIPNNLIGCIIG 296
Query: 439 KGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQYLITQRITYEQGV 498
+ G + E ++++GA+I+I+ V G+ R+VTITG+ A+ AQYLI R++ E+G+
Sbjct: 297 RQGANINEIRQMSGAQIKIANP---VEGSSGRQVTITGSAASISLAQYLINARLSSEKGM 353
Score = 70.9 bits (172), Expect = 3e-12
Identities = 57/232 (24%), Positives = 109/232 (46%), Gaps = 52/232 (22%)
Query: 42 TNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCL 101
T +G + +++L+ GSIIGK G+++ ++++E+GA I +S+ ER+
Sbjct: 6 TESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGN-----CPERIIT 60
Query: 102 IQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSS 161
+ G A+ I +K+ E + SS T + ++
Sbjct: 61 LTGPTNAIFKAFAMIIDKLEE---------------------------DINSSMTNSTAA 93
Query: 162 PSDPMTTSRANQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLS--QKPDGINLQER 219
P+T ++++VP + G +IGKGG +K + E +GA VQ++ P N ER
Sbjct: 94 SRPPVT------LRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLP---NSTER 144
Query: 220 VVTVSGEPEQNRKAVE----LIIQKIQEDPQSGSCLNISYANVTGPVANSNP 267
+T++G P+ + V+ ++++ + + PQ G + I Y P+ S+P
Sbjct: 145 AITIAGVPQSVTECVKQICLVMLETLSQSPQ-GRVMTIPYQ----PMPASSP 191
Score = 57.0 bits (136), Expect = 4e-08
Identities = 56/259 (21%), Positives = 102/259 (39%), Gaps = 66/259 (25%)
Query: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGT----VE 107
L++++P+ GS+IGKGG I ++++ TGA ++++ D P +TER I G E
Sbjct: 100 LRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVAG--DMLPNSTERAITIAGVPQSVTE 157
Query: 108 ALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTV----NPDRIKQTL--PSSPTTTKSS 161
+ + + E + + PQ T P + + V DR P + +
Sbjct: 158 CVKQICLVMLETLSQSPQGRVMTIPYQPMPASSPVICAGGQDRCSDAAGYPHATHDLEGP 217
Query: 162 PSD-----------PMTTSRANQV------------------------------------ 174
P D P+ ++ NQV
Sbjct: 218 PLDAYSIQGQHTISPLDLAKLNQVARQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDAS 277
Query: 175 -----KIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQ 229
++ +PN+ G IIG+ GA + + + SGA ++++ +G + R VT++G
Sbjct: 278 TQTTHELTIPNNLIGCIIGRQGANINEIRQMSGAQIKIANPVEGSS--GRQVTITGSAAS 335
Query: 230 NRKAVELIIQKIQEDPQSG 248
A LI ++ + G
Sbjct: 336 ISLAQYLINARLSSEKGMG 354
>gi|14670373 poly(rC) binding protein 4 isoform c [Homo sapiens]
Length = 403
Score = 75.9 bits (185), Expect = 8e-14
Identities = 77/332 (23%), Positives = 132/332 (39%), Gaps = 33/332 (9%)
Query: 174 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 233
+++++ G IIGK G TVK + EQS A + +S+ + ER+ T++G A
Sbjct: 20 LRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEG----SCPERITTITGSTAAVFHA 75
Query: 234 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHAN 293
V +I K+ ED + AN P V+P A+ L+G A
Sbjct: 76 VSMIAFKLDED-------------LCAAPANGGNVSRPPVTLRLVIP-ASQCGSLIGKAG 121
Query: 294 --LAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAAS 351
+ + G+ L T T++ + + A
Sbjct: 122 TKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATIP 181
Query: 352 ANPAAAAANLLATYASEASASGSTAGGTAGTFALGSLAAATAATNGYFGAASPLAASAIL 411
+P+ + +L + + G + G G + ++ A+P S +
Sbjct: 182 YHPSLSLGTVLLS-----ANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPFATP---SVVP 233
Query: 412 GTEKSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRK 471
G + T S E VP +L+G ++G+ G + E ++++GA I+I + E G R
Sbjct: 234 GLDPGTQTSSQ--EFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAE---GAGERH 288
Query: 472 VTITGTPAATQAAQYLITQRITYEQGVRAANP 503
VTITG+P + AQYLIT + + P
Sbjct: 289 VTITGSPVSIALAQYLITACLETAKSTSGGTP 320
Score = 72.8 bits (177), Expect = 7e-13
Identities = 69/263 (26%), Positives = 118/263 (44%), Gaps = 43/263 (16%)
Query: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
L+++IP+ GS+IGK G I ++++ TGA ++++ D P +TER + G +A+
Sbjct: 104 LRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAG--DLLPNSTERAVTVSGVPDAIIL 161
Query: 112 VHGFIAEKIREMPQN----------------VAKTEPVSILQPQTTVNPDRI-KQTLPSS 154
I I E P ++ + S+ V P + K SS
Sbjct: 162 CVRQICAVILESPPKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSS 221
Query: 155 PTTTKSSPS-----DPMTTSRANQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQ 209
++PS DP T + + + +VPN G +IG+ G+ + + + SGA +++
Sbjct: 222 HAVPFATPSVVPGLDPGTQTSSQE--FLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGN 279
Query: 210 KPDGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTG 269
+ +G ER VT++G P A LI +CL + + +G +S P
Sbjct: 280 QAEGAG--ERHVTITGSPVSIALAQYLIT----------ACLETA-KSTSGGTPSSAPAD 326
Query: 270 --SPYANTAEVLPTAAAAAGLLG 290
+P++ LPT A GLLG
Sbjct: 327 LPAPFSPPLTALPT--APPGLLG 347
Score = 63.9 bits (154), Expect = 3e-10
Identities = 55/202 (27%), Positives = 90/202 (44%), Gaps = 43/202 (21%)
Query: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
L++L+ GSIIGK G+T+ ++++++ A I +S+ ER+ I G+ A+
Sbjct: 20 LRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGS-----CPERITTITGSTAAVFH 74
Query: 112 VHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTTSRA 171
IA K+ E L ++P + P+T
Sbjct: 75 AVSMIAFKLDE---------------------------DLCAAPANGGNVSRPPVT---- 103
Query: 172 NQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQK--PDGINLQERVVTVSGEPEQ 229
+++++P S G +IGK G +K + E +GA VQ++ P N ER VTVSG P+
Sbjct: 104 --LRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLP---NSTERAVTVSGVPDA 158
Query: 230 NRKAVELIIQKIQEDPQSGSCL 251
V I I E P G+ +
Sbjct: 159 IILCVRQICAVILESPPKGATI 180
>gi|14670369 poly(rC) binding protein 4 isoform c [Homo sapiens]
Length = 403
Score = 75.9 bits (185), Expect = 8e-14
Identities = 77/332 (23%), Positives = 132/332 (39%), Gaps = 33/332 (9%)
Query: 174 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 233
+++++ G IIGK G TVK + EQS A + +S+ + ER+ T++G A
Sbjct: 20 LRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEG----SCPERITTITGSTAAVFHA 75
Query: 234 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHAN 293
V +I K+ ED + AN P V+P A+ L+G A
Sbjct: 76 VSMIAFKLDED-------------LCAAPANGGNVSRPPVTLRLVIP-ASQCGSLIGKAG 121
Query: 294 --LAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAAS 351
+ + G+ L T T++ + + A
Sbjct: 122 TKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATIP 181
Query: 352 ANPAAAAANLLATYASEASASGSTAGGTAGTFALGSLAAATAATNGYFGAASPLAASAIL 411
+P+ + +L + + G + G G + ++ A+P S +
Sbjct: 182 YHPSLSLGTVLLS-----ANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPFATP---SVVP 233
Query: 412 GTEKSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRK 471
G + T S E VP +L+G ++G+ G + E ++++GA I+I + E G R
Sbjct: 234 GLDPGTQTSSQ--EFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAE---GAGERH 288
Query: 472 VTITGTPAATQAAQYLITQRITYEQGVRAANP 503
VTITG+P + AQYLIT + + P
Sbjct: 289 VTITGSPVSIALAQYLITACLETAKSTSGGTP 320
Score = 72.8 bits (177), Expect = 7e-13
Identities = 69/263 (26%), Positives = 118/263 (44%), Gaps = 43/263 (16%)
Query: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
L+++IP+ GS+IGK G I ++++ TGA ++++ D P +TER + G +A+
Sbjct: 104 LRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAG--DLLPNSTERAVTVSGVPDAIIL 161
Query: 112 VHGFIAEKIREMPQN----------------VAKTEPVSILQPQTTVNPDRI-KQTLPSS 154
I I E P ++ + S+ V P + K SS
Sbjct: 162 CVRQICAVILESPPKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSS 221
Query: 155 PTTTKSSPS-----DPMTTSRANQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQ 209
++PS DP T + + + +VPN G +IG+ G+ + + + SGA +++
Sbjct: 222 HAVPFATPSVVPGLDPGTQTSSQE--FLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGN 279
Query: 210 KPDGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTG 269
+ +G ER VT++G P A LI +CL + + +G +S P
Sbjct: 280 QAEGAG--ERHVTITGSPVSIALAQYLIT----------ACLETA-KSTSGGTPSSAPAD 326
Query: 270 --SPYANTAEVLPTAAAAAGLLG 290
+P++ LPT A GLLG
Sbjct: 327 LPAPFSPPLTALPT--APPGLLG 347
Score = 63.9 bits (154), Expect = 3e-10
Identities = 55/202 (27%), Positives = 90/202 (44%), Gaps = 43/202 (21%)
Query: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
L++L+ GSIIGK G+T+ ++++++ A I +S+ ER+ I G+ A+
Sbjct: 20 LRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGS-----CPERITTITGSTAAVFH 74
Query: 112 VHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTTSRA 171
IA K+ E L ++P + P+T
Sbjct: 75 AVSMIAFKLDE---------------------------DLCAAPANGGNVSRPPVT---- 103
Query: 172 NQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQK--PDGINLQERVVTVSGEPEQ 229
+++++P S G +IGK G +K + E +GA VQ++ P N ER VTVSG P+
Sbjct: 104 --LRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLP---NSTERAVTVSGVPDA 158
Query: 230 NRKAVELIIQKIQEDPQSGSCL 251
V I I E P G+ +
Sbjct: 159 IILCVRQICAVILESPPKGATI 180
>gi|56118219 insulin-like growth factor 2 mRNA binding protein 2
isoform b [Homo sapiens]
Length = 556
Score = 73.9 bits (180), Expect = 3e-13
Identities = 56/198 (28%), Positives = 91/198 (45%), Gaps = 23/198 (11%)
Query: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
LK+L + G +IGK G+ + +++ ETG I +S +D ER ++GTVEA +
Sbjct: 277 LKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACAS 336
Query: 112 VHGFIAEKIREMPQN---VAKTEP--VSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPM 166
I +K+RE +N T S L P P + P
Sbjct: 337 AEIEIMKKLREAFENDMLAVNTHSGYFSSLYPHHQFGPFPHHHSYPEQEI---------- 386
Query: 167 TTSRANQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGE 226
V + +P G IIGK GA +K + +GA ++++ +G ++ ER+V ++G
Sbjct: 387 -------VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIA-PAEGPDVSERMVIITGP 438
Query: 227 PEQNRKAVELIIQKIQED 244
PE KA I K++E+
Sbjct: 439 PEAQFKAQGRIFGKLKEE 456
Score = 60.1 bits (144), Expect = 5e-09
Identities = 53/202 (26%), Positives = 90/202 (44%), Gaps = 45/202 (22%)
Query: 49 QYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEA 108
Q + + IP+ A G+IIGK G I QL + GA+IK++ ++ P +ER+ +I G EA
Sbjct: 384 QEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEG--PDVSERMVIITGPPEA 441
Query: 109 LNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNP-DRIKQTLPSSPTTTKSSPSDPMT 167
G I K++E + NP + +K
Sbjct: 442 QFKAQGRIFGKLKE----------------ENFFNPKEEVKL------------------ 467
Query: 168 TSRANQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGE- 226
+ I VP+STAG +IGKGG TV + + A V + + +E +V + G
Sbjct: 468 -----EAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHF 522
Query: 227 --PEQNRKAVELIIQKIQEDPQ 246
+ ++ + I+Q++++ Q
Sbjct: 523 FASQTAQRKIREIVQQVKQQEQ 544
Score = 47.0 bits (110), Expect = 4e-05
Identities = 27/84 (32%), Positives = 48/84 (57%), Gaps = 5/84 (5%)
Query: 165 PMTTSRANQV----KIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERV 220
P TS+A Q+ +I+VP G IIGK G T+K + +Q+ + V + +K + E+
Sbjct: 183 PGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRK-ENSGAAEKP 241
Query: 221 VTVSGEPEQNRKAVELIIQKIQED 244
VT+ PE +A +I++ +Q++
Sbjct: 242 VTIHATPEGTSEACRMILEIMQKE 265
Score = 41.2 bits (95), Expect = 0.002
Identities = 45/145 (31%), Positives = 63/145 (43%), Gaps = 24/145 (16%)
Query: 5 APIQQNGTHTGVPIDLDP---PDSRKRP--LEAPPEA---------GSTKRTN---TGED 47
A I+Q G I + P PD +R + PPEA G K N E+
Sbjct: 405 AHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKEENFFNPKEE 464
Query: 48 GQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCL-IQGTV 106
+ + +PS AG +IGKGG+T+ +LQ T A + + +D P E V + I G
Sbjct: 465 VKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIV--PRDQTPDENEEVIVRIIGHF 522
Query: 107 EALNAVHGFIAEKIREMPQNVAKTE 131
A KIRE+ Q V + E
Sbjct: 523 FASQTAQ----RKIREIVQQVKQQE 543
Score = 40.4 bits (93), Expect = 0.004
Identities = 24/67 (35%), Positives = 34/67 (50%), Gaps = 2/67 (2%)
Query: 424 VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQA 483
+ I VP VGAI+GK G T+ + T +R+ I +K G + VTI TP T
Sbjct: 196 LRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKEN--SGAAEKPVTIHATPEGTSE 253
Query: 484 AQYLITQ 490
A +I +
Sbjct: 254 ACRMILE 260
Score = 39.7 bits (91), Expect = 0.007
Identities = 25/75 (33%), Positives = 37/75 (49%), Gaps = 2/75 (2%)
Query: 421 KDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAA 480
+++V + +P VGAI+GK G + + GA I+I+ P R V ITG P A
Sbjct: 384 QEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEG--PDVSERMVIITGPPEA 441
Query: 481 TQAAQYLITQRITYE 495
AQ I ++ E
Sbjct: 442 QFKAQGRIFGKLKEE 456
Score = 38.9 bits (89), Expect = 0.011
Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 6/95 (6%)
Query: 414 EKSTDGSKDVVEIAVP----ENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRN 469
+K D +K EI + LVG ++GK G+ L + + TG +I IS +
Sbjct: 263 QKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPE 322
Query: 470 RKVTITGTPAATQAAQYLITQRI--TYEQGVRAAN 502
R +T+ GT A +A+ I +++ +E + A N
Sbjct: 323 RTITVKGTVEACASAEIEIMKKLREAFENDMLAVN 357
Score = 37.7 bits (86), Expect = 0.025
Identities = 27/81 (33%), Positives = 38/81 (46%), Gaps = 1/81 (1%)
Query: 426 IAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQ 485
I VP + G ++GKGGKT+ E Q LT A + I + + V I G A+Q AQ
Sbjct: 471 IRVPSSTAGRVIGKGGKTVNELQNLTSAEV-IVPRDQTPDENEEVIVRIIGHFFASQTAQ 529
Query: 486 YLITQRITYEQGVRAANPQKV 506
I + + + PQ V
Sbjct: 530 RKIREIVQQVKQQEQKYPQGV 550
>gi|64085377 insulin-like growth factor 2 mRNA binding protein 2
isoform a [Homo sapiens]
Length = 599
Score = 72.8 bits (177), Expect = 7e-13
Identities = 64/226 (28%), Positives = 100/226 (44%), Gaps = 36/226 (15%)
Query: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
LK+L + G +IGK G+ + +++ ETG I +S +D ER ++GTVEA +
Sbjct: 277 LKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACAS 336
Query: 112 VHGFIAEKIREMPQN-------VAKTEP-------------VSILQPQTTVNPDRIKQTL 151
I +K+RE +N A P +S+L P P
Sbjct: 337 AEIEIMKKLREAFENDMLAVNQQANLIPGLNLSALGIFSTGLSVLSP--PAGPRGAPPAA 394
Query: 152 PSSPTTTKSSPSD-----------PMTTSRANQ--VKIIVPNSTAGLIIGKGGATVKAVM 198
P P TT S P S Q V + +P G IIGK GA +K +
Sbjct: 395 PYHPFTTHSGYFSSLYPHHQFGPFPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLA 454
Query: 199 EQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQKIQED 244
+GA ++++ +G ++ ER+V ++G PE KA I K++E+
Sbjct: 455 RFAGASIKIA-PAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKEE 499
Score = 60.1 bits (144), Expect = 5e-09
Identities = 53/202 (26%), Positives = 90/202 (44%), Gaps = 45/202 (22%)
Query: 49 QYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEA 108
Q + + IP+ A G+IIGK G I QL + GA+IK++ ++ P +ER+ +I G EA
Sbjct: 427 QEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEG--PDVSERMVIITGPPEA 484
Query: 109 LNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNP-DRIKQTLPSSPTTTKSSPSDPMT 167
G I K++E + NP + +K
Sbjct: 485 QFKAQGRIFGKLKE----------------ENFFNPKEEVKL------------------ 510
Query: 168 TSRANQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGE- 226
+ I VP+STAG +IGKGG TV + + A V + + +E +V + G
Sbjct: 511 -----EAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHF 565
Query: 227 --PEQNRKAVELIIQKIQEDPQ 246
+ ++ + I+Q++++ Q
Sbjct: 566 FASQTAQRKIREIVQQVKQQEQ 587
Score = 59.3 bits (142), Expect = 8e-09
Identities = 90/358 (25%), Positives = 136/358 (37%), Gaps = 68/358 (18%)
Query: 165 PMTTSRANQV----KIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERV 220
P TS+A Q+ +I+VP G IIGK G T+K + +Q+ + V + +K + E+
Sbjct: 183 PGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRK-ENSGAAEKP 241
Query: 221 VTVSGEPEQNRKAVELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLP 280
VT+ PE +A +I++ +Q++ AE +P
Sbjct: 242 VTIHATPEGTSEACRMILEIMQKEADE-------------------------TKLAEEIP 276
Query: 281 TAAAAAGLLGHANLAGVAAFPAVLSGFTGNDLVAI---------TSALNTLASYGYNLNT 331
+L H L G L G G +L I S+L L+ Y
Sbjct: 277 LK-----ILAHNGLVG------RLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTI 325
Query: 332 LGLGLSQAAATGAL----AAAAASANPAAAA---ANLLATYASEASASGSTAGGTAGTFA 384
G +A A+ + A N A ANL+ A ST G + +
Sbjct: 326 TVKGTVEACASAEIEIMKKLREAFENDMLAVNQQANLIPGLNLSALGIFST-GLSVLSPP 384
Query: 385 LGSLAAATAAT-------NGYFGAASPLAASAILGTEKSTDGSKDVVEIAVPENLVGAIL 437
G A AA +GYF + P S +++V + +P VGAI+
Sbjct: 385 AGPRGAPPAAPYHPFTTHSGYFSSLYPHHQFGPFPHHHSYP-EQEIVNLFIPTQAVGAII 443
Query: 438 GKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQYLITQRITYE 495
GK G + + GA I+I+ P R V ITG P A AQ I ++ E
Sbjct: 444 GKKGAHIKQLARFAGASIKIAPAEG--PDVSERMVIITGPPEAQFKAQGRIFGKLKEE 499
Score = 55.1 bits (131), Expect = 2e-07
Identities = 105/500 (21%), Positives = 173/500 (34%), Gaps = 86/500 (17%)
Query: 22 PPDSRKRPLEAPPEAGSTKR-TNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETG 80
PP +R + E G T+ + L++L+P+ G+IIGK G TI + K+T
Sbjct: 165 PPQRAQRGDHSSREQGHAPGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQ 224
Query: 81 ATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQT 140
+ + + + ++ G E+ I T E + I E + Q
Sbjct: 225 SRVDIHRKEN--SGAAEKPVTIHATPEGTSEACRMILEIM------------------QK 264
Query: 141 TVNPDRIKQTLPSSPTTTKSSPSDPMTTSRANQVKIIVPNSTAGLIIGKGGATVKAVMEQ 200
+ ++ + +P +KI+ N G +IGK G +K + +
Sbjct: 265 EADETKLAEEIP---------------------LKILAHNGLVGRLIGKEGRNLKKIEHE 303
Query: 201 SGAWVQLSQKPD-GINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSGSCLNISYANVT 259
+G + +S D I ER +TV G E A I++K++E ++ AN+
Sbjct: 304 TGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNQQANLI 363
Query: 260 GPVANSNPTGSPYANTAEVLPTAAAAAGLLGHANLAGVAAFPAVLSGFTGNDLVA----- 314
P N + G ++ VL A G A S +
Sbjct: 364 -PGLNLSALGI-FSTGLSVLSPPAGPRGAPPAAPYHPFTTHSGYFSSLYPHHQFGPFPHH 421
Query: 315 -------ITSALNTLASYGYNLNTLGLGLSQAAA-TGALAAAAASANPAAAAANLLATYA 366
I + + G + G + Q A GA A + P + ++ T
Sbjct: 422 HSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGP 481
Query: 367 SEASASGSTAGGTAGTFALGSLAAATAATNGYFGAASPLAASAILGTEKSTDGSKDVVEI 426
EA A G + N +F + A + ST G
Sbjct: 482 PEAQFK-----------AQGRIFGKLKEEN-FFNPKEEVKLEAHIRVPSSTAG------- 522
Query: 427 AVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQY 486
++GKGGKT+ E Q LT A + I + + V I G A+Q AQ
Sbjct: 523 --------RVIGKGGKTVNELQNLTSAEV-IVPRDQTPDENEEVIVRIIGHFFASQTAQR 573
Query: 487 LITQRITYEQGVRAANPQKV 506
I + + + PQ V
Sbjct: 574 KIREIVQQVKQQEQKYPQGV 593
Score = 41.2 bits (95), Expect = 0.002
Identities = 45/145 (31%), Positives = 63/145 (43%), Gaps = 24/145 (16%)
Query: 5 APIQQNGTHTGVPIDLDP---PDSRKRP--LEAPPEA---------GSTKRTN---TGED 47
A I+Q G I + P PD +R + PPEA G K N E+
Sbjct: 448 AHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKEENFFNPKEE 507
Query: 48 GQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCL-IQGTV 106
+ + +PS AG +IGKGG+T+ +LQ T A + + +D P E V + I G
Sbjct: 508 VKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIV--PRDQTPDENEEVIVRIIGHF 565
Query: 107 EALNAVHGFIAEKIREMPQNVAKTE 131
A KIRE+ Q V + E
Sbjct: 566 FASQTAQ----RKIREIVQQVKQQE 586
>gi|30795212 insulin-like growth factor 2 mRNA binding protein 3
[Homo sapiens]
Length = 579
Score = 70.9 bits (172), Expect = 3e-12
Identities = 55/202 (27%), Positives = 94/202 (46%), Gaps = 12/202 (5%)
Query: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
LK+L + G +IGK G+ + +++++T I +S ++ ER ++G VE
Sbjct: 279 LKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAK 338
Query: 112 VHGFIAEKIREMPQN-VAKTEPVSILQPQTTVN------PDRIKQTLPSSPTTTKSSPSD 164
I +KIRE +N +A + L P +N P S P + + P
Sbjct: 339 AEEEIMKKIRESYENDIASMNLQAHLIPGLNLNALGLFPPTSGMPPPTSGPPSAMTPPYP 398
Query: 165 PMTTSRANQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQL--SQKPDGINLQERVVT 222
S V + +P + G IIGK G +K + +GA +++ ++ PD + R+V
Sbjct: 399 QFEQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDA---KVRMVI 455
Query: 223 VSGEPEQNRKAVELIIQKIQED 244
++G PE KA I KI+E+
Sbjct: 456 ITGPPEAQFKAQGRIYGKIKEE 477
Score = 57.4 bits (137), Expect = 3e-08
Identities = 62/234 (26%), Positives = 92/234 (39%), Gaps = 45/234 (19%)
Query: 18 IDLDPPDS-RKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQ 76
+ L PP S P PP A + + + + IP+ + G+IIGK GQ I QL
Sbjct: 373 LGLFPPTSGMPPPTSGPPSAMTPPYPQFEQSETETVHLFIPALSVGAIIGKQGQHIKQLS 432
Query: 77 KETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSIL 136
+ GA+IK++ ++ P R+ +I G EA G I KI+E V+ E V +
Sbjct: 433 RFAGASIKIAPAEA--PDAKVRMVIITGPPEAQFKAQGRIYGKIKE-ENFVSPKEEVKL- 488
Query: 137 QPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTTSRANQVKIIVPNSTAGLIIGKGGATVKA 196
+ I VP+ AG +IGKGG TV
Sbjct: 489 ------------------------------------EAHIRVPSFAAGRVIGKGGKTVNE 512
Query: 197 VMEQSGAWVQLSQKPDGINLQERVVTVSGE----PEQNRKAVELIIQKIQEDPQ 246
+ S A V + + + VV ++G RK E++ Q Q Q
Sbjct: 513 LQNLSSAEVVVPRDQTPDENDQVVVKITGHFYACQVAQRKIQEILTQVKQHQQQ 566
Score = 56.2 bits (134), Expect = 7e-08
Identities = 55/235 (23%), Positives = 100/235 (42%), Gaps = 53/235 (22%)
Query: 21 DPPDSRKRPLEAPP------EAGSTKRTNTGEDGQYF-----LKVLIPSYAAGSIIGKGG 69
D +++ PL+ P + GS+++ + G + L++L+P+ G+IIGK G
Sbjct: 156 DEMAAQQNPLQQPRGRRGLGQRGSSRQGSPGSVSKQKPCDLPLRLLVPTQFVGAIIGKEG 215
Query: 70 QTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAK 129
TI + K+T + I + + ++ G E+ I T E +A I E + + Q++
Sbjct: 216 ATIRNITKQTQSKIDVHRKEN--AGAAEKSITILSTPEGTSAACKSILEIMHKEAQDIKF 273
Query: 130 TEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTTSRANQVKIIVPNSTAGLIIGK 189
TE + + KI+ N+ G +IGK
Sbjct: 274 TEEIPL---------------------------------------KILAHNNFVGRLIGK 294
Query: 190 GGATVKAVMEQSGAWVQLSQKPD-GINLQERVVTVSGEPEQNRKAVELIIQKIQE 243
G +K + + + + +S + + ER +TV G E KA E I++KI+E
Sbjct: 295 EGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRE 349
Score = 42.7 bits (99), Expect = 8e-04
Identities = 34/145 (23%), Positives = 71/145 (48%), Gaps = 14/145 (9%)
Query: 107 EALNAVHGFIAE----KIREMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSP-TTTKSS 161
+AL+ ++GF E K+ +P +A + + QP+ + + SP + +K
Sbjct: 134 QALDKLNGFQLENFTLKVAYIPDEMAAQQN-PLQQPRGRRGLGQRGSSRQGSPGSVSKQK 192
Query: 162 PSDPMTTSRANQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVV 221
P D ++++VP G IIGK GAT++ + +Q+ + + + +K + E+ +
Sbjct: 193 PCDL-------PLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRK-ENAGAAEKSI 244
Query: 222 TVSGEPEQNRKAVELIIQKIQEDPQ 246
T+ PE A + I++ + ++ Q
Sbjct: 245 TILSTPEGTSAACKSILEIMHKEAQ 269
Score = 42.0 bits (97), Expect = 0.001
Identities = 39/138 (28%), Positives = 64/138 (46%), Gaps = 20/138 (14%)
Query: 7 IQQNGTHTGVPIDLDP---PDSRKRP--LEAPPEA---------GSTKRTN---TGEDGQ 49
I+Q G I + P PD++ R + PPEA G K N E+ +
Sbjct: 428 IKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIKEENFVSPKEEVK 487
Query: 50 YFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCL-IQGTVEA 108
+ +PS+AAG +IGKGG+T+ +LQ + A + + +D P ++V + I G A
Sbjct: 488 LEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVV--PRDQTPDENDQVVVKITGHFYA 545
Query: 109 LNAVHGFIAEKIREMPQN 126
I E + ++ Q+
Sbjct: 546 CQVAQRKIQEILTQVKQH 563
Score = 40.0 bits (92), Expect = 0.005
Identities = 21/61 (34%), Positives = 32/61 (52%), Gaps = 2/61 (3%)
Query: 424 VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQA 483
+ + VP VGAI+GK G T+ + T ++I + +K G + +TI TP T A
Sbjct: 198 LRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKEN--AGAAEKSITILSTPEGTSA 255
Query: 484 A 484
A
Sbjct: 256 A 256
Score = 39.7 bits (91), Expect = 0.007
Identities = 27/77 (35%), Positives = 38/77 (49%), Gaps = 2/77 (2%)
Query: 422 DVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAAT 481
+ V + +P VGAI+GK G+ + + GA I+I+ P + R V ITG P A
Sbjct: 406 ETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAE--APDAKVRMVIITGPPEAQ 463
Query: 482 QAAQYLITQRITYEQGV 498
AQ I +I E V
Sbjct: 464 FKAQGRIYGKIKEENFV 480
Score = 37.7 bits (86), Expect = 0.025
Identities = 25/69 (36%), Positives = 37/69 (53%), Gaps = 3/69 (4%)
Query: 426 IAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVT-ITGTPAATQAA 484
I VP G ++GKGGKT+ E Q L+ A + + + + P ++ V ITG A Q A
Sbjct: 492 IRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPR--DQTPDENDQVVVKITGHFYACQVA 549
Query: 485 QYLITQRIT 493
Q I + +T
Sbjct: 550 QRKIQEILT 558
Score = 37.0 bits (84), Expect = 0.042
Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 2/83 (2%)
Query: 424 VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQA 483
++I N VG ++GK G+ L + ++ T +I IS E R +T+ G
Sbjct: 279 LKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAK 338
Query: 484 AQYLITQRI--TYEQGVRAANPQ 504
A+ I ++I +YE + + N Q
Sbjct: 339 AEEEIMKKIRESYENDIASMNLQ 361
>gi|238624257 insulin-like growth factor 2 mRNA binding protein 1
isoform 2 [Homo sapiens]
Length = 438
Score = 68.6 bits (166), Expect = 1e-11
Identities = 55/213 (25%), Positives = 99/213 (46%), Gaps = 8/213 (3%)
Query: 39 TKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTER 98
+ R T + + LK+L + G +IGK G+ + +++++T I +S +D ER
Sbjct: 127 SNREQTRQADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPER 186
Query: 99 VCLIQGTVEALNAVHGFIAEKIREMPQN-VAKTEPVSILQPQTTVN-----PDRIKQTLP 152
++G +E I +K+RE +N VA S L P + P P
Sbjct: 187 TITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPP 246
Query: 153 SSPTTTKSSP-SDPMTTSRANQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKP 211
+ T ++P S M V++ +P G IIGK G +K + + A ++++ P
Sbjct: 247 PPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIA-PP 305
Query: 212 DGINLQERVVTVSGEPEQNRKAVELIIQKIQED 244
+ + + R+V ++G PE KA I K++E+
Sbjct: 306 ETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEE 338
Score = 51.6 bits (122), Expect = 2e-06
Identities = 50/203 (24%), Positives = 84/203 (41%), Gaps = 43/203 (21%)
Query: 49 QYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEA 108
Q ++V IP+ A G+IIGK GQ I QL + A+IK++ + P + R+ +I G EA
Sbjct: 266 QEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPET--PDSKVRMVIITGPPEA 323
Query: 109 LNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTT 168
G I K++E + P+ V +
Sbjct: 324 QFKAQGRIYGKLKEE----------NFFGPKEEVKLE----------------------- 350
Query: 169 SRANQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGE-- 226
I VP S AG +IGKGG TV + + A V + + + +V + G
Sbjct: 351 -----THIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQVIVKIIGHFY 405
Query: 227 -PEQNRKAVELIIQKIQEDPQSG 248
+ ++ + I+ ++++ Q G
Sbjct: 406 ASQMAQRKIRDILAQVKQQHQKG 428
Score = 40.0 bits (92), Expect = 0.005
Identities = 24/75 (32%), Positives = 40/75 (53%), Gaps = 2/75 (2%)
Query: 421 KDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAA 480
+++V++ +P VGAI+GK G+ + + A I+I+ P ++ R V ITG P A
Sbjct: 266 QEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPE--TPDSKVRMVIITGPPEA 323
Query: 481 TQAAQYLITQRITYE 495
AQ I ++ E
Sbjct: 324 QFKAQGRIYGKLKEE 338
Score = 38.5 bits (88), Expect = 0.015
Identities = 26/83 (31%), Positives = 42/83 (50%), Gaps = 14/83 (16%)
Query: 21 DPPDSRKRP--LEAPPEA---------GSTKRTN---TGEDGQYFLKVLIPSYAAGSIIG 66
+ PDS+ R + PPEA G K N E+ + + +P+ AAG +IG
Sbjct: 306 ETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIG 365
Query: 67 KGGQTIVQLQKETGATIKLSKSK 89
KGG+T+ +LQ T A + + + +
Sbjct: 366 KGGKTVNELQNLTAAEVVVPRDQ 388
Score = 37.0 bits (84), Expect = 0.042
Identities = 27/77 (35%), Positives = 42/77 (54%), Gaps = 7/77 (9%)
Query: 414 EKSTDGSKDVVE----IAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRN 469
E++ G K+ V+ I VP + G ++GKGGKT+ E Q LT A + + + + P +
Sbjct: 337 EENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPR--DQTPDEND 394
Query: 470 RK-VTITGTPAATQAAQ 485
+ V I G A+Q AQ
Sbjct: 395 QVIVKIIGHFYASQMAQ 411
Score = 33.9 bits (76), Expect = 0.36
Identities = 23/93 (24%), Positives = 43/93 (46%), Gaps = 2/93 (2%)
Query: 414 EKSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVT 473
E++ + ++I N VG ++GK G+ L + ++ T +I IS + R +T
Sbjct: 130 EQTRQADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTIT 189
Query: 474 ITGTPAATQAAQYLITQRI--TYEQGVRAANPQ 504
+ G A+ I +++ YE V A + Q
Sbjct: 190 VKGAIENCCRAEQEIMKKVREAYENDVAAMSLQ 222
>gi|56237027 insulin-like growth factor 2 mRNA binding protein 1
isoform 1 [Homo sapiens]
Length = 577
Score = 67.0 bits (162), Expect = 4e-11
Identities = 53/200 (26%), Positives = 94/200 (47%), Gaps = 8/200 (4%)
Query: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
LK+L + G +IGK G+ + +++++T I +S +D ER ++G +E
Sbjct: 279 LKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCR 338
Query: 112 VHGFIAEKIREMPQN-VAKTEPVSILQPQTTVN-----PDRIKQTLPSSPTTTKSSP-SD 164
I +K+RE +N VA S L P + P P + T ++P S
Sbjct: 339 AEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSS 398
Query: 165 PMTTSRANQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVS 224
M V++ +P G IIGK G +K + + A ++++ P+ + + R+V ++
Sbjct: 399 FMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIA-PPETPDSKVRMVIIT 457
Query: 225 GEPEQNRKAVELIIQKIQED 244
G PE KA I K++E+
Sbjct: 458 GPPEAQFKAQGRIYGKLKEE 477
Score = 53.9 bits (128), Expect = 3e-07
Identities = 72/329 (21%), Positives = 131/329 (39%), Gaps = 56/329 (17%)
Query: 174 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 233
++++VP G IIGK GAT++ + +Q+ + + + +K + E+ ++V PE A
Sbjct: 198 LRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRK-ENAGAAEKAISVHSTPEGCSSA 256
Query: 234 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHAN 293
++I++ + ++ + TA+ +P +L H N
Sbjct: 257 CKMILEIMHKEAKD-------------------------TKTADEVPLK-----ILAHNN 286
Query: 294 LAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAASAN 353
G L G G +L + T + +L L L + T A
Sbjct: 287 FVGR------LIGKEGRNLKKVEQDTETKITIS-SLQDLTLYNPERTITVKGAIENCCRA 339
Query: 354 PAAAAANLLATYASEASASGSTAGGTAGTFALGSLAAATAATNGYFGAAS---PLAASAI 410
+ Y ++ +A + G +LAA G F A+S P S++
Sbjct: 340 EQEIMKKVREAYENDVAAMSLQSHLIPGL----NLAAV-----GLFPASSSAVPPPPSSV 390
Query: 411 LGTEKSTD----GSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPG 466
G + +++V++ +P VGAI+GK G+ + + A I+I+ P
Sbjct: 391 TGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPE--TPD 448
Query: 467 TRNRKVTITGTPAATQAAQYLITQRITYE 495
++ R V ITG P A AQ I ++ E
Sbjct: 449 SKVRMVIITGPPEAQFKAQGRIYGKLKEE 477
Score = 52.0 bits (123), Expect = 1e-06
Identities = 65/293 (22%), Positives = 112/293 (38%), Gaps = 70/293 (23%)
Query: 25 SRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIK 84
SR +P + P A D L++L+P+ G+IIGK G TI + K+T + I
Sbjct: 173 SRGQPRQGSPVAAGAPAKQQQVDIP--LRLLVPTQYVGAIIGKEGATIRNITKQTQSKID 230
Query: 85 LSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNP 144
+ + ++ G E+ + T E ++ + I E+ AK
Sbjct: 231 VHRKEN--AGAAEKAISVHSTPEGCSSA----CKMILEIMHKEAK--------------- 269
Query: 145 DRIKQTLPSSPTTTKSSPSDPMTTSRANQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAW 204
TK++ P+ KI+ N+ G +IGK G +K V + +
Sbjct: 270 ------------DTKTADEVPL--------KILAHNNFVGRLIGKEGRNLKKVEQDTETK 309
Query: 205 VQLSQKPD-GINLQERVVTVSGEPEQNRKAVELIIQKIQED------------------- 244
+ +S D + ER +TV G E +A + I++K++E
Sbjct: 310 ITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLN 369
Query: 245 -------PQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLG 290
P S S + ++VTG S+ +P +V A A ++G
Sbjct: 370 LAAVGLFPASSSAVPPPPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIG 422
Score = 51.6 bits (122), Expect = 2e-06
Identities = 50/203 (24%), Positives = 84/203 (41%), Gaps = 43/203 (21%)
Query: 49 QYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEA 108
Q ++V IP+ A G+IIGK GQ I QL + A+IK++ + P + R+ +I G EA
Sbjct: 405 QEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPET--PDSKVRMVIITGPPEA 462
Query: 109 LNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTT 168
G I K++E + P+ V
Sbjct: 463 QFKAQGRIYGKLKE----------ENFFGPKEEVK------------------------- 487
Query: 169 SRANQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGE-- 226
+ I VP S AG +IGKGG TV + + A V + + + +V + G
Sbjct: 488 ---LETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQVIVKIIGHFY 544
Query: 227 -PEQNRKAVELIIQKIQEDPQSG 248
+ ++ + I+ ++++ Q G
Sbjct: 545 ASQMAQRKIRDILAQVKQQHQKG 567
Score = 38.5 bits (88), Expect = 0.015
Identities = 26/83 (31%), Positives = 42/83 (50%), Gaps = 14/83 (16%)
Query: 21 DPPDSRKRP--LEAPPEA---------GSTKRTN---TGEDGQYFLKVLIPSYAAGSIIG 66
+ PDS+ R + PPEA G K N E+ + + +P+ AAG +IG
Sbjct: 445 ETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIG 504
Query: 67 KGGQTIVQLQKETGATIKLSKSK 89
KGG+T+ +LQ T A + + + +
Sbjct: 505 KGGKTVNELQNLTAAEVVVPRDQ 527
Score = 37.0 bits (84), Expect = 0.042
Identities = 27/77 (35%), Positives = 42/77 (54%), Gaps = 7/77 (9%)
Query: 414 EKSTDGSKDVVE----IAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRN 469
E++ G K+ V+ I VP + G ++GKGGKT+ E Q LT A + + + + P +
Sbjct: 476 EENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPR--DQTPDEND 533
Query: 470 RK-VTITGTPAATQAAQ 485
+ V I G A+Q AQ
Sbjct: 534 QVIVKIIGHFYASQMAQ 550
Score = 35.4 bits (80), Expect = 0.12
Identities = 22/95 (23%), Positives = 42/95 (44%), Gaps = 3/95 (3%)
Query: 397 GYFGAASPLAASAILGTEKSTDGSKDV-VEIAVPENLVGAILGKGGKTLVEYQELTGARI 455
G+ P S + + D+ + + VP VGAI+GK G T+ + T ++I
Sbjct: 170 GFGSRGQPRQGSPVAAGAPAKQQQVDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKI 229
Query: 456 QISKKGEFVPGTRNRKVTITGTPAATQAAQYLITQ 490
+ +K G + +++ TP +A +I +
Sbjct: 230 DVHRKEN--AGAAEKAISVHSTPEGCSSACKMILE 262
Score = 33.5 bits (75), Expect = 0.47
Identities = 25/93 (26%), Positives = 44/93 (47%), Gaps = 3/93 (3%)
Query: 415 KSTDGSKDV-VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVT 473
K T + +V ++I N VG ++GK G+ L + ++ T +I IS + R +T
Sbjct: 269 KDTKTADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTIT 328
Query: 474 ITGTPAATQAAQYLITQRI--TYEQGVRAANPQ 504
+ G A+ I +++ YE V A + Q
Sbjct: 329 VKGAIENCCRAEQEIMKKVREAYENDVAAMSLQ 361
>gi|17402900 far upstream element-binding protein [Homo sapiens]
Length = 644
Score = 66.6 bits (161), Expect = 5e-11
Identities = 57/233 (24%), Positives = 105/233 (45%), Gaps = 52/233 (22%)
Query: 19 DLDPPDSRKRP-------LEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQT 71
D D PD++K + PP R+ E+ + +P G IIG+GG+
Sbjct: 69 DGDQPDAKKVAPQNDSFGTQLPPMHQQQSRSVMTEEYK------VPDGMVGFIIGRGGEQ 122
Query: 72 IVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTE 131
I ++Q+E+G I+++ G ER C++ GT E++ + R + Q V K
Sbjct: 123 ISRIQQESGCKIQIAPDSG---GLPERSCMLTGTPESVQSAK-------RLLDQIVEKGR 172
Query: 132 PVSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTTSRANQVK-IIVPNSTAGLIIGKG 190
P +P N V+ I++P S AGL+IGKG
Sbjct: 173 P----------------------------APGFHHGDGPGNAVQEIMIPASKAGLVIGKG 204
Query: 191 GATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQKIQE 243
G T+K + E++G + + Q ++ + ++G+P + ++A E++++ I++
Sbjct: 205 GETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEMVLELIRD 257
Score = 64.7 bits (156), Expect = 2e-10
Identities = 59/213 (27%), Positives = 89/213 (41%), Gaps = 30/213 (14%)
Query: 31 EAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKD 90
E E GS N G D V IP +A G +IG+ G+ I ++Q + G I+
Sbjct: 263 EVRNEYGSRIGGNEGID------VPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDD- 315
Query: 91 FYPGTT-ERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQ 149
GTT ER+ I G + I + +R + Q P +
Sbjct: 316 ---GTTPERIAQITGPPDRCQHAAEIITDLLRSV-------------QAGNPGGPGPGGR 359
Query: 150 TLPSSPTTTKSSPSDPMTTSRANQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQ 209
P + + IVP GLIIGKGG T+K++ +QSGA ++L +
Sbjct: 360 GRGRGQGNWNMGPPGGL-----QEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQR 414
Query: 210 K-PDGINLQERVVTVSGEPEQNRKAVELIIQKI 241
P + ++ T+ G P+Q A +LI +KI
Sbjct: 415 NPPPNADPNMKLFTIRGTPQQIDYARQLIEEKI 447
Score = 57.0 bits (136), Expect = 4e-08
Identities = 45/197 (22%), Positives = 84/197 (42%), Gaps = 48/197 (24%)
Query: 48 GQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVE 107
G +++IP+ AG +IGKGG+TI QLQ+ G + +
Sbjct: 184 GNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVM---------------------- 221
Query: 108 ALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQT------LPSSPTTTKSS 161
I++ PQN +P+ I T +P +++Q L +
Sbjct: 222 ------------IQDGPQNTGADKPLRI-----TGDPYKVQQAKEMVLELIRDQGGFREV 264
Query: 162 PSDPMTTSRANQ-VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERV 220
++ + N+ + + +P G++IG+ G +K + +G +Q KPD ER+
Sbjct: 265 RNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQF--KPDDGTTPERI 322
Query: 221 VTVSGEPEQNRKAVELI 237
++G P++ + A E+I
Sbjct: 323 AQITGPPDRCQHAAEII 339
Score = 47.8 bits (112), Expect = 2e-05
Identities = 24/66 (36%), Positives = 40/66 (60%), Gaps = 3/66 (4%)
Query: 425 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAA 484
E VP+ +VG I+G+GG+ + Q+ +G +IQI+ +P R +TGTP + Q+A
Sbjct: 104 EYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLP---ERSCMLTGTPESVQSA 160
Query: 485 QYLITQ 490
+ L+ Q
Sbjct: 161 KRLLDQ 166
Score = 45.1 bits (105), Expect = 2e-04
Identities = 24/77 (31%), Positives = 43/77 (55%), Gaps = 1/77 (1%)
Query: 423 VVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQ 482
V EI +P + G ++GKGG+T+ + QE G ++ + + G G ++ + ITG P Q
Sbjct: 187 VQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGA-DKPLRITGDPYKVQ 245
Query: 483 AAQYLITQRITYEQGVR 499
A+ ++ + I + G R
Sbjct: 246 QAKEMVLELIRDQGGFR 262
Score = 42.0 bits (97), Expect = 0.001
Identities = 22/65 (33%), Positives = 34/65 (52%)
Query: 428 VPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQYL 487
VP G I+GKGG+T+ + +GARI++ + + TI GTP A+ L
Sbjct: 383 VPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQL 442
Query: 488 ITQRI 492
I ++I
Sbjct: 443 IEEKI 447
Score = 41.2 bits (95), Expect = 0.002
Identities = 25/85 (29%), Positives = 40/85 (47%), Gaps = 6/85 (7%)
Query: 419 GSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTP 478
G + +++ +P VG ++G+ G+ + + Q G RIQ P R ITG P
Sbjct: 273 GGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTP---ERIAQITGPP 329
Query: 479 AATQAAQYLITQRITYEQGVRAANP 503
Q A +IT + + V+A NP
Sbjct: 330 DRCQHAAEIITDLL---RSVQAGNP 351
>gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a
[Homo sapiens]
Length = 464
Score = 63.5 bits (153), Expect = 4e-10
Identities = 60/235 (25%), Positives = 102/235 (43%), Gaps = 48/235 (20%)
Query: 27 KRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLS 86
KRP E E + KR+ D L++L+ S AG++IGKGG+ I L+ + A++ +
Sbjct: 21 KRPAEDMEEEQAFKRSRN-TDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVP 79
Query: 87 KSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDR 146
S ER+ I +E + + I + E Q
Sbjct: 80 DSSG-----PERILSISADIETIGEILKKIIPTLEEGLQ--------------------- 113
Query: 147 IKQTLPSSPTTTKSSPSDPMTTSRAN-----------QVKIIVPNSTAGLIIGKGGATVK 195
LP SPT T P + N ++++++ S AG IIG GA +K
Sbjct: 114 ----LP-SPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIK 168
Query: 196 AVMEQSGAWVQLSQK--PDGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSG 248
+ E + ++L Q+ P + +RVV + G+P++ + +++I+ I E P G
Sbjct: 169 ELRENTQTTIKLFQECCP---HSTDRVVLIGGKPDRVVECIKIILDLISESPIKG 220
Score = 51.2 bits (121), Expect = 2e-06
Identities = 25/68 (36%), Positives = 44/68 (64%), Gaps = 3/68 (4%)
Query: 425 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAA 484
++ +P++L G+I+GKGG+ + + + +GA I+I E + G+ +R +TITGT Q A
Sbjct: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKID---EPLEGSEDRIITITGTQDQIQNA 447
Query: 485 QYLITQRI 492
QYL+ +
Sbjct: 448 QYLLQNSV 455
Score = 48.9 bits (115), Expect = 1e-05
Identities = 25/70 (35%), Positives = 42/70 (60%), Gaps = 3/70 (4%)
Query: 53 KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAV 112
+V IP AGSIIGKGGQ I Q++ E+GA+IK+ + + G+ +R+ I GT + +
Sbjct: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLE---GSEDRIITITGTQDQIQNA 447
Query: 113 HGFIAEKIRE 122
+ +++
Sbjct: 448 QYLLQNSVKQ 457
Score = 47.0 bits (110), Expect = 4e-05
Identities = 20/69 (28%), Positives = 43/69 (62%), Gaps = 2/69 (2%)
Query: 175 KIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAV 234
++ +P AG IIGKGG +K + +SGA +++ + +G ++R++T++G +Q + A
Sbjct: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEG--SEDRIITITGTQDQIQNAQ 448
Query: 235 ELIIQKIQE 243
L+ +++
Sbjct: 449 YLLQNSVKQ 457
>gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b
[Homo sapiens]
Length = 463
Score = 63.5 bits (153), Expect = 4e-10
Identities = 60/235 (25%), Positives = 102/235 (43%), Gaps = 48/235 (20%)
Query: 27 KRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLS 86
KRP E E + KR+ D L++L+ S AG++IGKGG+ I L+ + A++ +
Sbjct: 21 KRPAEDMEEEQAFKRSRN-TDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVP 79
Query: 87 KSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDR 146
S ER+ I +E + + I + E Q
Sbjct: 80 DSSG-----PERILSISADIETIGEILKKIIPTLEEGLQ--------------------- 113
Query: 147 IKQTLPSSPTTTKSSPSDPMTTSRAN-----------QVKIIVPNSTAGLIIGKGGATVK 195
LP SPT T P + N ++++++ S AG IIG GA +K
Sbjct: 114 ----LP-SPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIK 168
Query: 196 AVMEQSGAWVQLSQK--PDGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSG 248
+ E + ++L Q+ P + +RVV + G+P++ + +++I+ I E P G
Sbjct: 169 ELRENTQTTIKLFQECCP---HSTDRVVLIGGKPDRVVECIKIILDLISESPIKG 220
Score = 52.0 bits (123), Expect = 1e-06
Identities = 26/73 (35%), Positives = 45/73 (61%), Gaps = 3/73 (4%)
Query: 425 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAA 484
++ +P++L G+I+GKGG+ + + + +GA I+I E + G+ +R +TITGT Q A
Sbjct: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKID---EPLEGSEDRIITITGTQDQIQNA 447
Query: 485 QYLITQRITYEQG 497
QYL+ + G
Sbjct: 448 QYLLQNSVKQYSG 460
Score = 48.9 bits (115), Expect = 1e-05
Identities = 25/70 (35%), Positives = 42/70 (60%), Gaps = 3/70 (4%)
Query: 53 KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAV 112
+V IP AGSIIGKGGQ I Q++ E+GA+IK+ + + G+ +R+ I GT + +
Sbjct: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLE---GSEDRIITITGTQDQIQNA 447
Query: 113 HGFIAEKIRE 122
+ +++
Sbjct: 448 QYLLQNSVKQ 457
Score = 47.0 bits (110), Expect = 4e-05
Identities = 20/69 (28%), Positives = 43/69 (62%), Gaps = 2/69 (2%)
Query: 175 KIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAV 234
++ +P AG IIGKGG +K + +SGA +++ + +G ++R++T++G +Q + A
Sbjct: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEG--SEDRIITITGTQDQIQNAQ 448
Query: 235 ELIIQKIQE 243
L+ +++
Sbjct: 449 YLLQNSVKQ 457
>gi|14165437 heterogeneous nuclear ribonucleoprotein K isoform a
[Homo sapiens]
Length = 464
Score = 63.5 bits (153), Expect = 4e-10
Identities = 60/235 (25%), Positives = 102/235 (43%), Gaps = 48/235 (20%)
Query: 27 KRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLS 86
KRP E E + KR+ D L++L+ S AG++IGKGG+ I L+ + A++ +
Sbjct: 21 KRPAEDMEEEQAFKRSRN-TDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVP 79
Query: 87 KSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDR 146
S ER+ I +E + + I + E Q
Sbjct: 80 DSSG-----PERILSISADIETIGEILKKIIPTLEEGLQ--------------------- 113
Query: 147 IKQTLPSSPTTTKSSPSDPMTTSRAN-----------QVKIIVPNSTAGLIIGKGGATVK 195
LP SPT T P + N ++++++ S AG IIG GA +K
Sbjct: 114 ----LP-SPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIK 168
Query: 196 AVMEQSGAWVQLSQK--PDGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSG 248
+ E + ++L Q+ P + +RVV + G+P++ + +++I+ I E P G
Sbjct: 169 ELRENTQTTIKLFQECCP---HSTDRVVLIGGKPDRVVECIKIILDLISESPIKG 220
Score = 51.2 bits (121), Expect = 2e-06
Identities = 25/68 (36%), Positives = 44/68 (64%), Gaps = 3/68 (4%)
Query: 425 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAA 484
++ +P++L G+I+GKGG+ + + + +GA I+I E + G+ +R +TITGT Q A
Sbjct: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKID---EPLEGSEDRIITITGTQDQIQNA 447
Query: 485 QYLITQRI 492
QYL+ +
Sbjct: 448 QYLLQNSV 455
Score = 48.9 bits (115), Expect = 1e-05
Identities = 25/70 (35%), Positives = 42/70 (60%), Gaps = 3/70 (4%)
Query: 53 KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAV 112
+V IP AGSIIGKGGQ I Q++ E+GA+IK+ + + G+ +R+ I GT + +
Sbjct: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLE---GSEDRIITITGTQDQIQNA 447
Query: 113 HGFIAEKIRE 122
+ +++
Sbjct: 448 QYLLQNSVKQ 457
Score = 47.0 bits (110), Expect = 4e-05
Identities = 20/69 (28%), Positives = 43/69 (62%), Gaps = 2/69 (2%)
Query: 175 KIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAV 234
++ +P AG IIGKGG +K + +SGA +++ + +G ++R++T++G +Q + A
Sbjct: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEG--SEDRIITITGTQDQIQNAQ 448
Query: 235 ELIIQKIQE 243
L+ +++
Sbjct: 449 YLLQNSVKQ 457
>gi|145312259 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 63.2 bits (152), Expect = 6e-10
Identities = 57/212 (26%), Positives = 93/212 (43%), Gaps = 51/212 (24%)
Query: 35 EAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPG 94
E+ + T GED +++ +P A IIG+ G I QL+K+TGA I + D
Sbjct: 39 ESREERLTFVGED-DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV----DTEDV 93
Query: 95 TTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSS 154
ERV LI G P V K + I Q L
Sbjct: 94 GDERVLLISG------------------FPVQVCKAKAA-------------IHQIL--- 119
Query: 155 PTTTKSSPSDPMTTSRANQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGI 214
T+++P ++ VP + G IIG+GG T++++ + SGA + ++ +G
Sbjct: 120 ---TENTPVSE---------QLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGT 167
Query: 215 NLQERVVTVSGEPEQNRKAVELIIQKIQEDPQ 246
L R++ +SG ++ A LI++K+ ED +
Sbjct: 168 LLLSRLIKISGTQKEVAAAKHLILEKVSEDEE 199
Score = 47.4 bits (111), Expect = 3e-05
Identities = 55/235 (23%), Positives = 93/235 (39%), Gaps = 47/235 (20%)
Query: 5 APIQQNGTHTGVPIDLDPPDSRKR--------PLEAPPEAGSTKRTNTGEDGQYFLKVLI 56
A I+Q TG ID+D D P++ + + T E+ ++ +
Sbjct: 73 ANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAKAAIHQILT-ENTPVSEQLSV 131
Query: 57 PSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGT--TERVCLIQGTVEALNAVHG 114
P + G IIG+GG+TI + K +GA I K + GT R+ I GT + + A
Sbjct: 132 PQRSVGRIIGRGGETIRSICKASGAKITCDKESE---GTLLLSRLIKISGTQKEVAAAKH 188
Query: 115 FIAEKIREMPQ-----------NVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPS 163
I EK+ E + V + +P+S+ + T P + T++ P+
Sbjct: 189 LILEKVSEDEELRKRIAHSAETRVPRKQPISVRREDMT-EPGGAGEPALWKNTSSSMEPT 247
Query: 164 DPMTTSRANQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQE 218
P+ T KGG + V+ + G+W +KP + Q+
Sbjct: 248 APLVTPPP-----------------KGGGDMAVVVSKEGSW----EKPSDDSFQK 281
Score = 47.0 bits (110), Expect = 4e-05
Identities = 25/77 (32%), Positives = 49/77 (63%), Gaps = 5/77 (6%)
Query: 425 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGT--RNRKVTITGTPAATQ 482
+++VP+ VG I+G+GG+T+ + +GA+I K+ E GT +R + I+GT
Sbjct: 128 QLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESE---GTLLLSRLIKISGTQKEVA 184
Query: 483 AAQYLITQRITYEQGVR 499
AA++LI ++++ ++ +R
Sbjct: 185 AAKHLILEKVSEDEELR 201
Score = 43.1 bits (100), Expect = 6e-04
Identities = 27/86 (31%), Positives = 46/86 (53%), Gaps = 3/86 (3%)
Query: 173 QVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRK 232
++++ VP LIIG+ GA +K + +Q+GA + + + G ERV+ +SG P Q K
Sbjct: 54 EIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVG---DERVLLISGFPVQVCK 110
Query: 233 AVELIIQKIQEDPQSGSCLNISYANV 258
A I Q + E+ L++ +V
Sbjct: 111 AKAAIHQILTENTPVSEQLSVPQRSV 136
Score = 32.7 bits (73), Expect = 0.80
Identities = 22/76 (28%), Positives = 38/76 (50%), Gaps = 5/76 (6%)
Query: 419 GSKDV-VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGT 477
G D+ +E+ VP+ V I+G+ G + + ++ TGARI + + R + I+G
Sbjct: 49 GEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDV----GDERVLLISGF 104
Query: 478 PAATQAAQYLITQRIT 493
P A+ I Q +T
Sbjct: 105 PVQVCKAKAAIHQILT 120
>gi|145312270 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 63.2 bits (152), Expect = 6e-10
Identities = 57/212 (26%), Positives = 93/212 (43%), Gaps = 51/212 (24%)
Query: 35 EAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPG 94
E+ + T GED +++ +P A IIG+ G I QL+K+TGA I + D
Sbjct: 39 ESREERLTFVGED-DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV----DTEDV 93
Query: 95 TTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSS 154
ERV LI G P V K + I Q L
Sbjct: 94 GDERVLLISG------------------FPVQVCKAKAA-------------IHQIL--- 119
Query: 155 PTTTKSSPSDPMTTSRANQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGI 214
T+++P ++ VP + G IIG+GG T++++ + SGA + ++ +G
Sbjct: 120 ---TENTPVSE---------QLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGT 167
Query: 215 NLQERVVTVSGEPEQNRKAVELIIQKIQEDPQ 246
L R++ +SG ++ A LI++K+ ED +
Sbjct: 168 LLLSRLIKISGTQKEVAAAKHLILEKVSEDEE 199
Score = 47.4 bits (111), Expect = 3e-05
Identities = 55/235 (23%), Positives = 93/235 (39%), Gaps = 47/235 (20%)
Query: 5 APIQQNGTHTGVPIDLDPPDSRKR--------PLEAPPEAGSTKRTNTGEDGQYFLKVLI 56
A I+Q TG ID+D D P++ + + T E+ ++ +
Sbjct: 73 ANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAKAAIHQILT-ENTPVSEQLSV 131
Query: 57 PSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGT--TERVCLIQGTVEALNAVHG 114
P + G IIG+GG+TI + K +GA I K + GT R+ I GT + + A
Sbjct: 132 PQRSVGRIIGRGGETIRSICKASGAKITCDKESE---GTLLLSRLIKISGTQKEVAAAKH 188
Query: 115 FIAEKIREMPQ-----------NVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPS 163
I EK+ E + V + +P+S+ + T P + T++ P+
Sbjct: 189 LILEKVSEDEELRKRIAHSAETRVPRKQPISVRREDMT-EPGGAGEPALWKNTSSSMEPT 247
Query: 164 DPMTTSRANQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQE 218
P+ T KGG + V+ + G+W +KP + Q+
Sbjct: 248 APLVTPPP-----------------KGGGDMAVVVSKEGSW----EKPSDDSFQK 281
Score = 47.0 bits (110), Expect = 4e-05
Identities = 25/77 (32%), Positives = 49/77 (63%), Gaps = 5/77 (6%)
Query: 425 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGT--RNRKVTITGTPAATQ 482
+++VP+ VG I+G+GG+T+ + +GA+I K+ E GT +R + I+GT
Sbjct: 128 QLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESE---GTLLLSRLIKISGTQKEVA 184
Query: 483 AAQYLITQRITYEQGVR 499
AA++LI ++++ ++ +R
Sbjct: 185 AAKHLILEKVSEDEELR 201
Score = 43.1 bits (100), Expect = 6e-04
Identities = 27/86 (31%), Positives = 46/86 (53%), Gaps = 3/86 (3%)
Query: 173 QVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRK 232
++++ VP LIIG+ GA +K + +Q+GA + + + G ERV+ +SG P Q K
Sbjct: 54 EIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVG---DERVLLISGFPVQVCK 110
Query: 233 AVELIIQKIQEDPQSGSCLNISYANV 258
A I Q + E+ L++ +V
Sbjct: 111 AKAAIHQILTENTPVSEQLSVPQRSV 136
Score = 32.7 bits (73), Expect = 0.80
Identities = 22/76 (28%), Positives = 38/76 (50%), Gaps = 5/76 (6%)
Query: 419 GSKDV-VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGT 477
G D+ +E+ VP+ V I+G+ G + + ++ TGARI + + R + I+G
Sbjct: 49 GEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDV----GDERVLLISGF 104
Query: 478 PAATQAAQYLITQRIT 493
P A+ I Q +T
Sbjct: 105 PVQVCKAKAAIHQILT 120
>gi|145312256 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 63.2 bits (152), Expect = 6e-10
Identities = 57/212 (26%), Positives = 93/212 (43%), Gaps = 51/212 (24%)
Query: 35 EAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPG 94
E+ + T GED +++ +P A IIG+ G I QL+K+TGA I + D
Sbjct: 39 ESREERLTFVGED-DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV----DTEDV 93
Query: 95 TTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSS 154
ERV LI G P V K + I Q L
Sbjct: 94 GDERVLLISG------------------FPVQVCKAKAA-------------IHQIL--- 119
Query: 155 PTTTKSSPSDPMTTSRANQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGI 214
T+++P ++ VP + G IIG+GG T++++ + SGA + ++ +G
Sbjct: 120 ---TENTPVSE---------QLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGT 167
Query: 215 NLQERVVTVSGEPEQNRKAVELIIQKIQEDPQ 246
L R++ +SG ++ A LI++K+ ED +
Sbjct: 168 LLLSRLIKISGTQKEVAAAKHLILEKVSEDEE 199
Score = 47.4 bits (111), Expect = 3e-05
Identities = 55/235 (23%), Positives = 93/235 (39%), Gaps = 47/235 (20%)
Query: 5 APIQQNGTHTGVPIDLDPPDSRKR--------PLEAPPEAGSTKRTNTGEDGQYFLKVLI 56
A I+Q TG ID+D D P++ + + T E+ ++ +
Sbjct: 73 ANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAKAAIHQILT-ENTPVSEQLSV 131
Query: 57 PSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGT--TERVCLIQGTVEALNAVHG 114
P + G IIG+GG+TI + K +GA I K + GT R+ I GT + + A
Sbjct: 132 PQRSVGRIIGRGGETIRSICKASGAKITCDKESE---GTLLLSRLIKISGTQKEVAAAKH 188
Query: 115 FIAEKIREMPQ-----------NVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPS 163
I EK+ E + V + +P+S+ + T P + T++ P+
Sbjct: 189 LILEKVSEDEELRKRIAHSAETRVPRKQPISVRREDMT-EPGGAGEPALWKNTSSSMEPT 247
Query: 164 DPMTTSRANQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQE 218
P+ T KGG + V+ + G+W +KP + Q+
Sbjct: 248 APLVTPPP-----------------KGGGDMAVVVSKEGSW----EKPSDDSFQK 281
Score = 47.0 bits (110), Expect = 4e-05
Identities = 25/77 (32%), Positives = 49/77 (63%), Gaps = 5/77 (6%)
Query: 425 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGT--RNRKVTITGTPAATQ 482
+++VP+ VG I+G+GG+T+ + +GA+I K+ E GT +R + I+GT
Sbjct: 128 QLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESE---GTLLLSRLIKISGTQKEVA 184
Query: 483 AAQYLITQRITYEQGVR 499
AA++LI ++++ ++ +R
Sbjct: 185 AAKHLILEKVSEDEELR 201
Score = 43.1 bits (100), Expect = 6e-04
Identities = 27/86 (31%), Positives = 46/86 (53%), Gaps = 3/86 (3%)
Query: 173 QVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRK 232
++++ VP LIIG+ GA +K + +Q+GA + + + G ERV+ +SG P Q K
Sbjct: 54 EIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVG---DERVLLISGFPVQVCK 110
Query: 233 AVELIIQKIQEDPQSGSCLNISYANV 258
A I Q + E+ L++ +V
Sbjct: 111 AKAAIHQILTENTPVSEQLSVPQRSV 136
Score = 32.7 bits (73), Expect = 0.80
Identities = 22/76 (28%), Positives = 38/76 (50%), Gaps = 5/76 (6%)
Query: 419 GSKDV-VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGT 477
G D+ +E+ VP+ V I+G+ G + + ++ TGARI + + R + I+G
Sbjct: 49 GEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDV----GDERVLLISGF 104
Query: 478 PAATQAAQYLITQRIT 493
P A+ I Q +T
Sbjct: 105 PVQVCKAKAAIHQILT 120
>gi|100816392 far upstream element (FUSE) binding protein 3 [Homo
sapiens]
Length = 572
Score = 61.2 bits (147), Expect = 2e-09
Identities = 60/258 (23%), Positives = 98/258 (37%), Gaps = 32/258 (12%)
Query: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
++V +P +A G +IG+ G+ I ++Q + G I+ P ER + G +
Sbjct: 256 IEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISP---ERAAQVMGPPDRCQH 312
Query: 112 VHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTTSRA 171
I+E I T D +
Sbjct: 313 AAHIISELIL------------------TAQERDGFGGLAAARGRGRGRGDWSVGAPGGV 354
Query: 172 NQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQK-PDGINLQERVVTVSGEPEQN 230
++ VP GL+IGKGG +K++ +QSGA V+L + P + R T+ G P+Q
Sbjct: 355 QEITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQI 414
Query: 231 RKAVELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAA---AAAG 287
A +LI +K+ N+ G S P P+ NT + AA
Sbjct: 415 EVARQLIDEKV-------GGTNLGAPGAFGQSPFSQPPAPPHQNTFPPRSSGCFPNMAAK 467
Query: 288 LLGHANLAGVAAFPAVLS 305
+ G+ + V+ PA L+
Sbjct: 468 VNGNPHSTPVSGPPAFLT 485
Score = 60.8 bits (146), Expect = 3e-09
Identities = 45/195 (23%), Positives = 88/195 (45%), Gaps = 43/195 (22%)
Query: 56 IPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVH-- 113
+P G IIG+GG+ I ++Q E+G I+++ G ER C++ GT E++
Sbjct: 84 VPDKMVGFIIGRGGEQISRIQAESGCKIQIASESS---GIPERPCVLTGTPESIEQAKRL 140
Query: 114 -GFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTTSRAN 172
G I ++ R P + S +Q
Sbjct: 141 LGQIVDRCRNGPGFHNDIDSNSTIQ----------------------------------- 165
Query: 173 QVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRK 232
+I++P S GL+IG+GG T+K + E++G + + Q ++ + ++G+ + ++
Sbjct: 166 --EILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQ 223
Query: 233 AVELIIQKIQEDPQS 247
A E++++ I+E Q+
Sbjct: 224 AREMVLEIIREKDQA 238
Score = 57.0 bits (136), Expect = 4e-08
Identities = 44/189 (23%), Positives = 75/189 (39%), Gaps = 33/189 (17%)
Query: 53 KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAV 112
++LIP+ G +IG+GG+TI QLQ+ TG + + + P ++ I G +
Sbjct: 166 EILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPL-PTGADKPLRITGDAFKVQQA 224
Query: 113 HGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTTSRAN 172
+ E IRE Q + D +
Sbjct: 225 REMVLEIIREKDQ------------------------------ADFRGVRGDFNSRMGGG 254
Query: 173 QVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRK 232
+++ VP G++IG+ G +K + +G +Q KPD ER V G P++ +
Sbjct: 255 SIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQF--KPDDGISPERAAQVMGPPDRCQH 312
Query: 233 AVELIIQKI 241
A +I + I
Sbjct: 313 AAHIISELI 321
Score = 47.0 bits (110), Expect = 4e-05
Identities = 23/66 (34%), Positives = 39/66 (59%), Gaps = 3/66 (4%)
Query: 425 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAA 484
E VP+ +VG I+G+GG+ + Q +G +IQI+ + +P R +TGTP + + A
Sbjct: 81 EFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIP---ERPCVLTGTPESIEQA 137
Query: 485 QYLITQ 490
+ L+ Q
Sbjct: 138 KRLLGQ 143
Score = 46.2 bits (108), Expect = 7e-05
Identities = 23/81 (28%), Positives = 45/81 (55%), Gaps = 1/81 (1%)
Query: 412 GTEKSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRK 471
G D + + EI +P + VG ++G+GG+T+ + QE TG ++ + + G +P ++
Sbjct: 153 GFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGP-LPTGADKP 211
Query: 472 VTITGTPAATQAAQYLITQRI 492
+ ITG Q A+ ++ + I
Sbjct: 212 LRITGDAFKVQQAREMVLEII 232
Score = 40.0 bits (92), Expect = 0.005
Identities = 18/74 (24%), Positives = 36/74 (48%)
Query: 419 GSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTP 478
G + VP + G ++GKGG+ + + +GA +++ + R+ TI G P
Sbjct: 352 GGVQEITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVP 411
Query: 479 AATQAAQYLITQRI 492
+ A+ LI +++
Sbjct: 412 QQIEVARQLIDEKV 425
Score = 38.1 bits (87), Expect = 0.019
Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 3/73 (4%)
Query: 424 VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQA 483
+E++VP VG ++G+ G+ + + Q G RIQ P R + G P Q
Sbjct: 256 IEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISP---ERAAQVMGPPDRCQH 312
Query: 484 AQYLITQRITYEQ 496
A ++I++ I Q
Sbjct: 313 AAHIISELILTAQ 325
>gi|9966803 poly(rC) binding protein 4 isoform a [Homo sapiens]
Length = 424
Score = 58.2 bits (139), Expect = 2e-08
Identities = 34/103 (33%), Positives = 54/103 (52%), Gaps = 6/103 (5%)
Query: 402 ASPLAASAIL-GTEKSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKK 460
A P A +++ G + T S E VP +L+G ++G+ G + E ++++GA I+I +
Sbjct: 244 AVPFATPSVVPGLDPGTQTSSQ--EFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQ 301
Query: 461 GEFVPGTRNRKVTITGTPAATQAAQYLITQRITYEQGVRAANP 503
E G R VTITG+P + AQYLIT + + P
Sbjct: 302 AE---GAGERHVTITGSPVSIALAQYLITACLETAKSTSGGTP 341
Score = 51.6 bits (122), Expect = 2e-06
Identities = 59/236 (25%), Positives = 99/236 (41%), Gaps = 43/236 (18%)
Query: 79 TGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQN------------ 126
TGA ++++ D P +TER + G +A+ I I E P
Sbjct: 152 TGAQVQVAG--DLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATIPYHPSLSL 209
Query: 127 ----VAKTEPVSILQPQTTVNPDRI-KQTLPSSPTTTKSSPS-----DPMTTSRANQVKI 176
++ + S+ V P + K SS ++PS DP T + + +
Sbjct: 210 GTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPFATPSVVPGLDPGTQTSSQE--F 267
Query: 177 IVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAVEL 236
+VPN G +IG+ G+ + + + SGA +++ + +G ER VT++G P A L
Sbjct: 268 LVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAG--ERHVTITGSPVSIALAQYL 325
Query: 237 IIQKIQEDPQSGSCLNISYANVTGPVANSNPTG--SPYANTAEVLPTAAAAAGLLG 290
I +CL + + +G +S P +P++ LPT A GLLG
Sbjct: 326 IT----------ACLETA-KSTSGGTPSSAPADLPAPFSPPLTALPT--APPGLLG 368
Score = 29.6 bits (65), Expect = 6.8
Identities = 16/51 (31%), Positives = 28/51 (54%), Gaps = 3/51 (5%)
Query: 55 LIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGT 105
L+P+ G +IG+ G I ++++ +GA IK+ + G ER I G+
Sbjct: 268 LVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAE---GAGERHVTITGS 315
Score = 29.3 bits (64), Expect = 8.8
Identities = 14/57 (24%), Positives = 29/57 (50%), Gaps = 6/57 (10%)
Query: 146 RIKQTLPSSPTTTKSSPSDPMTTSRANQVKIIVPNSTAGLIIGKGGATVKAVMEQSG 202
++ + L ++P + P+T +++++P S G +IGK G +K + E G
Sbjct: 48 KLDEDLCAAPANGGNVSRPPVT------LRLVIPASQCGSLIGKAGTKIKEIREVRG 98
Score = 29.3 bits (64), Expect = 8.8
Identities = 12/32 (37%), Positives = 22/32 (68%), Gaps = 2/32 (6%)
Query: 449 ELTGARIQISKKGEFVPGTRNRKVTITGTPAA 480
+ TGA++Q++ G+ +P + R VT++G P A
Sbjct: 150 QTTGAQVQVA--GDLLPNSTERAVTVSGVPDA 179
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.126 0.345
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,823,954
Number of Sequences: 37866
Number of extensions: 867897
Number of successful extensions: 6069
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 105
Number of HSP's successfully gapped in prelim test: 164
Number of HSP's that attempted gapping in prelim test: 4113
Number of HSP's gapped (non-prelim): 1415
length of query: 507
length of database: 18,247,518
effective HSP length: 107
effective length of query: 400
effective length of database: 14,195,856
effective search space: 5678342400
effective search space used: 5678342400
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.