Guide to the Human Genome
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Search of human proteins with 56549125

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|56549125 dynamin 2 isoform 4 [Homo sapiens]
         (866 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|56549125 dynamin 2 isoform 4 [Homo sapiens]                       1717   0.0  
gi|56549123 dynamin 2 isoform 2 [Homo sapiens]                       1711   0.0  
gi|56549119 dynamin 2 isoform 3 [Homo sapiens]                       1700   0.0  
gi|56549121 dynamin 2 isoform 1 [Homo sapiens]                       1694   0.0  
gi|209915561 dynamin 3 isoform b [Homo sapiens]                      1377   0.0  
gi|42544243 dynamin 3 isoform a [Homo sapiens]                       1373   0.0  
gi|59853099 dynamin 1 isoform 1 [Homo sapiens]                       1352   0.0  
gi|56549117 dynamin 1 isoform 2 [Homo sapiens]                       1343   0.0  
gi|171460914 dynamin 1-like isoform 1 [Homo sapiens]                  499   e-141
gi|171460918 dynamin 1-like isoform 3 [Homo sapiens]                  452   e-127
gi|171460916 dynamin 1-like isoform 2 [Homo sapiens]                  452   e-127
gi|222136619 myxovirus resistance protein 1 [Homo sapiens]            239   1e-62
gi|222136617 myxovirus resistance protein 1 [Homo sapiens]            239   1e-62
gi|11342664 myxovirus resistance protein 2 [Homo sapiens]             223   6e-58
gi|239756350 PREDICTED: UPF0621 protein C-like [Homo sapiens]         122   2e-27
gi|239750876 PREDICTED: UPF0621 protein C-like [Homo sapiens]         122   2e-27
gi|169208224 PREDICTED: UPF0621 protein C-like [Homo sapiens]         122   2e-27
gi|224831253 optic atrophy 1 isoform 8 [Homo sapiens]                 114   4e-25
gi|224831251 optic atrophy 1 isoform 7 [Homo sapiens]                 114   4e-25
gi|18860841 optic atrophy 1 isoform 6 [Homo sapiens]                  114   4e-25
gi|224831248 optic atrophy 1 isoform 5 [Homo sapiens]                 114   4e-25
gi|18860835 optic atrophy 1 isoform 4 [Homo sapiens]                  114   4e-25
gi|18860833 optic atrophy 1 isoform 3 [Homo sapiens]                  114   4e-25
gi|18860831 optic atrophy 1 isoform 2 [Homo sapiens]                  114   4e-25
gi|224831243 optic atrophy 1 isoform 1 [Homo sapiens]                 114   4e-25
gi|113425405 PREDICTED: similar to dynamin 1 [Homo sapiens]            91   5e-18
gi|239745270 PREDICTED: hypothetical protein XP_002343416 [Homo ...    88   4e-17
gi|239745262 PREDICTED: hypothetical protein XP_002343372 [Homo ...    88   4e-17
gi|239745286 PREDICTED: hypothetical protein XP_002343417 [Homo ...    84   7e-16
gi|7706501 WW domain binding protein 11 [Homo sapiens]                 59   3e-08

>gi|56549125 dynamin 2 isoform 4 [Homo sapiens]
          Length = 866

 Score = 1717 bits (4447), Expect = 0.0
 Identities = 866/866 (100%), Positives = 866/866 (100%)

Query: 1   MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
           MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG
Sbjct: 1   MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60

Query: 61  SGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPI 120
           SGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPI
Sbjct: 61  SGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPI 120

Query: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD 180
           NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD
Sbjct: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD 180

Query: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240
           LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK
Sbjct: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240

Query: 241 DIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKL 300
           DIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKL
Sbjct: 241 DIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKL 300

Query: 301 QSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGA 360
           QSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGA
Sbjct: 301 QSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGA 360

Query: 361 RINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAFEAIVKKQIVKL 420
           RINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAFEAIVKKQIVKL
Sbjct: 361 RINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAFEAIVKKQIVKL 420

Query: 421 KEPSLKCVDLVVSELATVIKKCAEKLSSYPRLREETERIVTTYIREREGRTKDQILLLID 480
           KEPSLKCVDLVVSELATVIKKCAEKLSSYPRLREETERIVTTYIREREGRTKDQILLLID
Sbjct: 421 KEPSLKCVDLVVSELATVIKKCAEKLSSYPRLREETERIVTTYIREREGRTKDQILLLID 480

Query: 481 IEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQVIRRGWLTINNISLMKGGSKEYWFV 540
           IEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQVIRRGWLTINNISLMKGGSKEYWFV
Sbjct: 481 IEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQVIRRGWLTINNISLMKGGSKEYWFV 540

Query: 541 LTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIE 600
           LTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIE
Sbjct: 541 LTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIE 600

Query: 601 LACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYV 660
           LACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYV
Sbjct: 601 LACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYV 660

Query: 661 AIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLR 720
           AIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLR
Sbjct: 661 AIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLR 720

Query: 721 MYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAV 780
           MYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAV
Sbjct: 721 MYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAV 780

Query: 781 RGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPP 840
           RGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPP
Sbjct: 781 RGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPP 840

Query: 841 GVPSRRPPAAPSRPTIIRPAEPSLLD 866
           GVPSRRPPAAPSRPTIIRPAEPSLLD
Sbjct: 841 GVPSRRPPAAPSRPTIIRPAEPSLLD 866


>gi|56549123 dynamin 2 isoform 2 [Homo sapiens]
          Length = 870

 Score = 1711 bits (4432), Expect = 0.0
 Identities = 866/870 (99%), Positives = 866/870 (99%), Gaps = 4/870 (0%)

Query: 1   MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
           MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG
Sbjct: 1   MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60

Query: 61  SGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPI 120
           SGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPI
Sbjct: 61  SGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPI 120

Query: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD 180
           NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD
Sbjct: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD 180

Query: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240
           LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK
Sbjct: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240

Query: 241 DIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKL 300
           DIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKL
Sbjct: 241 DIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKL 300

Query: 301 QSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGA 360
           QSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGA
Sbjct: 301 QSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGA 360

Query: 361 RINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAFEAIVKKQIVKL 420
           RINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAFEAIVKKQIVKL
Sbjct: 361 RINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAFEAIVKKQIVKL 420

Query: 421 KEPSLKCVDLVVSELATVIKKCAEKLSSYPRLREETERIVTTYIREREGRTKDQILLLID 480
           KEPSLKCVDLVVSELATVIKKCAEKLSSYPRLREETERIVTTYIREREGRTKDQILLLID
Sbjct: 421 KEPSLKCVDLVVSELATVIKKCAEKLSSYPRLREETERIVTTYIREREGRTKDQILLLID 480

Query: 481 IEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQ----VIRRGWLTINNISLMKGGSKE 536
           IEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQ    VIRRGWLTINNISLMKGGSKE
Sbjct: 481 IEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKE 540

Query: 537 YWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDL 596
           YWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDL
Sbjct: 541 YWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDL 600

Query: 597 RQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLV 656
           RQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLV
Sbjct: 601 RQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLV 660

Query: 657 DSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRD 716
           DSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRD
Sbjct: 661 DSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRD 720

Query: 717 DMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGR 776
           DMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGR
Sbjct: 721 DMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGR 780

Query: 777 PPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPP 836
           PPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPP
Sbjct: 781 PPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPP 840

Query: 837 GIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 866
           GIPPGVPSRRPPAAPSRPTIIRPAEPSLLD
Sbjct: 841 GIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 870


>gi|56549119 dynamin 2 isoform 3 [Homo sapiens]
          Length = 866

 Score = 1700 bits (4402), Expect = 0.0
 Identities = 853/866 (98%), Positives = 859/866 (99%)

Query: 1   MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
           MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG
Sbjct: 1   MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60

Query: 61  SGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPI 120
           SGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPI
Sbjct: 61  SGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPI 120

Query: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD 180
           NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD
Sbjct: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD 180

Query: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240
           LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK
Sbjct: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240

Query: 241 DIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKL 300
           DIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKL
Sbjct: 241 DIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKL 300

Query: 301 QSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGA 360
           QSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGA
Sbjct: 301 QSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGA 360

Query: 361 RINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAFEAIVKKQIVKL 420
           RINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPD+AFEAIVKKQ+VKL
Sbjct: 361 RINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKL 420

Query: 421 KEPSLKCVDLVVSELATVIKKCAEKLSSYPRLREETERIVTTYIREREGRTKDQILLLID 480
           KEP LKCVDLV+ EL   +++C  KLSSYPRLREETERIVTTYIREREGRTKDQILLLID
Sbjct: 421 KEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLID 480

Query: 481 IEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQVIRRGWLTINNISLMKGGSKEYWFV 540
           IEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQVIRRGWLTINNISLMKGGSKEYWFV
Sbjct: 481 IEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQVIRRGWLTINNISLMKGGSKEYWFV 540

Query: 541 LTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIE 600
           LTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIE
Sbjct: 541 LTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIE 600

Query: 601 LACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYV 660
           LACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYV
Sbjct: 601 LACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYV 660

Query: 661 AIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLR 720
           AIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLR
Sbjct: 661 AIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLR 720

Query: 721 MYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAV 780
           MYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAV
Sbjct: 721 MYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAV 780

Query: 781 RGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPP 840
           RGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPP
Sbjct: 781 RGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPP 840

Query: 841 GVPSRRPPAAPSRPTIIRPAEPSLLD 866
           GVPSRRPPAAPSRPTIIRPAEPSLLD
Sbjct: 841 GVPSRRPPAAPSRPTIIRPAEPSLLD 866


>gi|56549121 dynamin 2 isoform 1 [Homo sapiens]
          Length = 870

 Score = 1694 bits (4387), Expect = 0.0
 Identities = 853/870 (98%), Positives = 859/870 (98%), Gaps = 4/870 (0%)

Query: 1   MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
           MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG
Sbjct: 1   MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60

Query: 61  SGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPI 120
           SGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPI
Sbjct: 61  SGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPI 120

Query: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD 180
           NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD
Sbjct: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD 180

Query: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240
           LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK
Sbjct: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240

Query: 241 DIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKL 300
           DIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKL
Sbjct: 241 DIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKL 300

Query: 301 QSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGA 360
           QSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGA
Sbjct: 301 QSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGA 360

Query: 361 RINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAFEAIVKKQIVKL 420
           RINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPD+AFEAIVKKQ+VKL
Sbjct: 361 RINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKL 420

Query: 421 KEPSLKCVDLVVSELATVIKKCAEKLSSYPRLREETERIVTTYIREREGRTKDQILLLID 480
           KEP LKCVDLV+ EL   +++C  KLSSYPRLREETERIVTTYIREREGRTKDQILLLID
Sbjct: 421 KEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLID 480

Query: 481 IEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQ----VIRRGWLTINNISLMKGGSKE 536
           IEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQ    VIRRGWLTINNISLMKGGSKE
Sbjct: 481 IEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKE 540

Query: 537 YWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDL 596
           YWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDL
Sbjct: 541 YWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDL 600

Query: 597 RQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLV 656
           RQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLV
Sbjct: 601 RQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLV 660

Query: 657 DSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRD 716
           DSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRD
Sbjct: 661 DSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRD 720

Query: 717 DMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGR 776
           DMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGR
Sbjct: 721 DMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGR 780

Query: 777 PPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPP 836
           PPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPP
Sbjct: 781 PPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPP 840

Query: 837 GIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 866
           GIPPGVPSRRPPAAPSRPTIIRPAEPSLLD
Sbjct: 841 GIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 870


>gi|209915561 dynamin 3 isoform b [Homo sapiens]
          Length = 859

 Score = 1377 bits (3565), Expect = 0.0
 Identities = 695/870 (79%), Positives = 769/870 (88%), Gaps = 15/870 (1%)

Query: 1   MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
           MGNR MEELIPLVN+LQDAFS++GQSC L+LPQIAVVGGQSAGKSSVLENFVGRDFLPRG
Sbjct: 1   MGNREMEELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60

Query: 61  SGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPI 120
           SGIVTRRPL+LQL+ SK E+AEFLHCK KKFTDFDEVR EIEAETDRVTG NKGIS +PI
Sbjct: 61  SGIVTRRPLVLQLVTSKAEYAEFLHCKGKKFTDFDEVRLEIEAETDRVTGMNKGISSIPI 120

Query: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD 180
           NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQI++MI+QFI+RE+ LILAVTPAN D
Sbjct: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANTD 180

Query: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240
           LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGY+GVVNRSQK
Sbjct: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYVGVVNRSQK 240

Query: 241 DIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKL 300
           DI+GKKDI+AA+ AERKFFLSHPAYRH+ADRMGTPHLQK LNQQLTNHIR++LP  R+KL
Sbjct: 241 DIDGKKDIKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQLTNHIRDTLPNFRNKL 300

Query: 301 QSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGA 360
           Q QLLS+E EVE YKNF+P+DPTRKTKALLQMVQQF VDFEKRIEGSGDQVDTLELSGGA
Sbjct: 301 QGQLLSIEHEVEAYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGDQVDTLELSGGA 360

Query: 361 RINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAFEAIVKKQIVKL 420
           +INRIFHERFPFE+VKMEF+EK+LRREISYAIKNIHG+RTGLFTPDMAFEAIVKKQIVKL
Sbjct: 361 KINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAFEAIVKKQIVKL 420

Query: 421 KEPSLKCVDLVVSELATVIKKCAEKLSSYPRLREETERIVTTYIREREGRTKDQILLLID 480
           K PSLK VDLV+ EL   +KKC +KL+++PRL EETERIV  +IREREG+TKDQ+LLLID
Sbjct: 421 KGPSLKSVDLVIQELINTVKKCTKKLANFPRLCEETERIVANHIREREGKTKDQVLLLID 480

Query: 481 IEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQVIRRGWLTINNISLMKGGSKEYWFV 540
           I+ SYINTNHEDFIGFANAQQRS+Q++KK  + NQVIR+GWLTI+NI +MKGGSK YWFV
Sbjct: 481 IQVSYINTNHEDFIGFANAQQRSSQVHKKTTVGNQVIRKGWLTISNIGIMKGGSKGYWFV 540

Query: 541 LTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIE 600
           LTAESLSWYKD+EEKEKKYMLPLDNLK+RDVEK FMS+KH+FA+FNTEQRNVYKD R +E
Sbjct: 541 LTAESLSWYKDDEEKEKKYMLPLDNLKVRDVEKSFMSSKHIFALFNTEQRNVYKDYRFLE 600

Query: 601 LACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYV 660
           LACDSQEDVDSWKAS LRAGVYP+K  AEN++  Q   FSMDPQLERQVETIRNLVDSY+
Sbjct: 601 LACDSQEDVDSWKASLLRAGVYPDKSVAENDENGQAENFSMDPQLERQVETIRNLVDSYM 660

Query: 661 AIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLR 720
           +IINK IRDL+PKTIMHLMINN K FI+ ELLA LYSS DQ++LMEESA+QAQRRD+MLR
Sbjct: 661 SIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLMEESAEQAQRRDEMLR 720

Query: 721 MYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSH---SPTPQRRPVSSIHPPGRP 777
           MY ALKEAL IIGDIST+TVSTP PPPVDD+W+Q +      SPT QRRP  S  P  RP
Sbjct: 721 MYQALKEALGIIGDISTATVSTPAPPPVDDSWIQHSRRSPPPSPTTQRRPTLSA-PLARP 779

Query: 778 PAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVF-ANSDLFPAPPQIPSRPVRIPP 836
            + RGP P    IP P        APP+P RPGP   F ++SD F APPQ+PSRP R   
Sbjct: 780 TSGRGPAPA---IPSP---GPHSGAPPVPFRPGPLPPFPSSSDSFGAPPQVPSRPTR--- 830

Query: 837 GIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 866
             PP VPSRRPP +P+RPTIIRP E SLLD
Sbjct: 831 -APPSVPSRRPPPSPTRPTIIRPLESSLLD 859


>gi|42544243 dynamin 3 isoform a [Homo sapiens]
          Length = 863

 Score = 1373 bits (3554), Expect = 0.0
 Identities = 695/874 (79%), Positives = 771/874 (88%), Gaps = 19/874 (2%)

Query: 1   MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
           MGNR MEELIPLVN+LQDAFS++GQSC L+LPQIAVVGGQSAGKSSVLENFVGRDFLPRG
Sbjct: 1   MGNREMEELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60

Query: 61  SGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPI 120
           SGIVTRRPL+LQL+ SK E+AEFLHCK KKFTDFDEVR EIEAETDRVTG NKGIS +PI
Sbjct: 61  SGIVTRRPLVLQLVTSKAEYAEFLHCKGKKFTDFDEVRLEIEAETDRVTGMNKGISSIPI 120

Query: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD 180
           NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQI++MI+QFI+RE+ LILAVTPAN D
Sbjct: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANTD 180

Query: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240
           LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGY+GVVNRSQK
Sbjct: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYVGVVNRSQK 240

Query: 241 DIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKL 300
           DI+GKKDI+AA+ AERKFFLSHPAYRH+ADRMGTPHLQK LNQQLTNHIR++LP  R+KL
Sbjct: 241 DIDGKKDIKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQLTNHIRDTLPNFRNKL 300

Query: 301 QSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGA 360
           Q QLLS+E EVE YKNF+P+DPTRKTKALLQMVQQF VDFEKRIEGSGDQVDTLELSGGA
Sbjct: 301 QGQLLSIEHEVEAYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGDQVDTLELSGGA 360

Query: 361 RINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAFEAIVKKQIVKL 420
           +INRIFHERFPFE+VKMEF+EK+LRREISYAIKNIHG+RTGLFTPDMAFEAIVKKQIVKL
Sbjct: 361 KINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAFEAIVKKQIVKL 420

Query: 421 KEPSLKCVDLVVSELATVIKKCAEKLSSYPRLREETERIVTTYIREREGRTKDQILLLID 480
           K PSLK VDLV+ EL   +KKC +KL+++PRL EETERIV  +IREREG+TKDQ+LLLID
Sbjct: 421 KGPSLKSVDLVIQELINTVKKCTKKLANFPRLCEETERIVANHIREREGKTKDQVLLLID 480

Query: 481 IEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQVIRRGWLTINNISLMKGGSKEYWFV 540
           I+ SYINTNHEDFIGFANAQQRS+Q++KK  + NQVIR+GWLTI+NI +MKGGSK YWFV
Sbjct: 481 IQVSYINTNHEDFIGFANAQQRSSQVHKKTTVGNQVIRKGWLTISNIGIMKGGSKGYWFV 540

Query: 541 LTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIE 600
           LTAESLSWYKD+EEKEKKYMLPLDNLK+RDVEK FMS+KH+FA+FNTEQRNVYKD R +E
Sbjct: 541 LTAESLSWYKDDEEKEKKYMLPLDNLKVRDVEKSFMSSKHIFALFNTEQRNVYKDYRFLE 600

Query: 601 LACDSQEDVDSWKASFLRAGVYPEK----DQAENEDGAQENTFSMDPQLERQVETIRNLV 656
           LACDSQEDVDSWKAS LRAGVYP+K    ++AEN++  Q   FSMDPQLERQVETIRNLV
Sbjct: 601 LACDSQEDVDSWKASLLRAGVYPDKSVGNNKAENDENGQAENFSMDPQLERQVETIRNLV 660

Query: 657 DSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRD 716
           DSY++IINK IRDL+PKTIMHLMINN K FI+ ELLA LYSS DQ++LMEESA+QAQRRD
Sbjct: 661 DSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLMEESAEQAQRRD 720

Query: 717 DMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSH---SPTPQRRPVSSIHP 773
           +MLRMY ALKEAL IIGDIST+TVSTP PPPVDD+W+Q +      SPT QRRP  S  P
Sbjct: 721 EMLRMYQALKEALGIIGDISTATVSTPAPPPVDDSWIQHSRRSPPPSPTTQRRPTLSA-P 779

Query: 774 PGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVF-ANSDLFPAPPQIPSRPV 832
             RP + RGP P    IP P        APP+P RPGP   F ++SD F APPQ+PSRP 
Sbjct: 780 LARPTSGRGPAPA---IPSP---GPHSGAPPVPFRPGPLPPFPSSSDSFGAPPQVPSRPT 833

Query: 833 RIPPGIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 866
           R     PP VPSRRPP +P+RPTIIRP E SLLD
Sbjct: 834 R----APPSVPSRRPPPSPTRPTIIRPLESSLLD 863


>gi|59853099 dynamin 1 isoform 1 [Homo sapiens]
          Length = 864

 Score = 1352 bits (3500), Expect = 0.0
 Identities = 683/877 (77%), Positives = 769/877 (87%), Gaps = 35/877 (3%)

Query: 1   MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
           MGNRGME+LIPLVN+LQDAFS+IGQ+  LDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG
Sbjct: 1   MGNRGMEDLIPLVNRLQDAFSAIGQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60

Query: 61  SGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPI 120
           SGIVTRRPL+LQL+ + TE+AEFLHCK KKFTDF+EVR EIEAETDRVTGTNKGISPVPI
Sbjct: 61  SGIVTRRPLVLQLVNATTEYAEFLHCKGKKFTDFEEVRLEIEAETDRVTGTNKGISPVPI 120

Query: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD 180
           NLRVYSPHVLNLTL+DLPG+TKVPVGDQPPDIE+QI+DM++QF+++E+ LILAV+PAN D
Sbjct: 121 NLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANSD 180

Query: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240
           LANSDALK+AKEVDPQG RTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK
Sbjct: 181 LANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240

Query: 241 DIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKL 300
           DI+GKKDI AALAAERKFFLSHP+YRH+ADRMGTP+LQK LNQQLTNHIR++LP LR+KL
Sbjct: 241 DIDGKKDITAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQLTNHIRDTLPGLRNKL 300

Query: 301 QSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGA 360
           QSQLLS+EKEVEEYKNFRPDDP RKTKALLQMVQQF VDFEKRIEGSGDQ+DT ELSGGA
Sbjct: 301 QSQLLSIEKEVEEYKNFRPDDPARKTKALLQMVQQFAVDFEKRIEGSGDQIDTYELSGGA 360

Query: 361 RINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAFEAIVKKQIVKL 420
           RINRIFHERFPFELVKMEFDEK+LRREISYAIKNIHG+RTGLFTPDMAFE IVKKQ+ K+
Sbjct: 361 RINRIFHERFPFELVKMEFDEKELRREISYAIKNIHGIRTGLFTPDMAFETIVKKQVKKI 420

Query: 421 KEPSLKCVDLVVSELATVIKKCAEKLSSYPRLREETERIVTTYIREREGRTKDQILLLID 480
           +EP LKCVD+V+SEL + +++C +KL  YPRLREE ERIVTT+IREREGRTK+Q++LLID
Sbjct: 421 REPCLKCVDMVISELISTVRQCTKKLQQYPRLREEMERIVTTHIREREGRTKEQVMLLID 480

Query: 481 IEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQ----VIRRGWLTINNISLMKGGSKE 536
           IE +Y+NTNHEDFIGFANAQQRS Q+NKK+   NQ    VIR+GWLTINNI +MKGGSKE
Sbjct: 481 IELAYMNTNHEDFIGFANAQQRSNQMNKKKTSGNQDEILVIRKGWLTINNIGIMKGGSKE 540

Query: 537 YWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDL 596
           YWFVLTAE+LSWYKD+EEKEKKYML +DNLK+RDVEKGFMS+KH+FA+FNTEQRNVYKD 
Sbjct: 541 YWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDY 600

Query: 597 RQIELACDSQEDVDSWKASFLRAGVYP------EKDQAENEDGAQENTFSMDPQLERQVE 650
           RQ+ELAC++QE+VDSWKASFLRAGVYP      EK     E+G+     SMDPQLERQVE
Sbjct: 601 RQLELACETQEEVDSWKASFLRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVE 660

Query: 651 TIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESAD 710
           TIRNLVDSY+AI+NK++RDLMPKTIMHLMINNTK FI  ELLA LYS  DQ++LMEESA+
Sbjct: 661 TIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELLANLYSCGDQNTLMEESAE 720

Query: 711 QAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSAS--------SHSPT 762
           QAQRRD+MLRMYHALKEAL+IIGDI+T+TVSTP+PPPVDD+WLQ  S        + SPT
Sbjct: 721 QAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPT 780

Query: 763 PQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFP 822
           PQRR  +   PP RP + RGP PGPP    P G+A    APP+PSRPG     A+ D F 
Sbjct: 781 PQRR--APAVPPARPGS-RGPAPGPP----PAGSALG-GAPPVPSRPG-----ASPDPFG 827

Query: 823 APPQIPSRPVRIPPGIPPGVPSRRPPAAPSRPTIIRP 859
            PPQ+PSRP R     PPGVPSR   A+PSRP   RP
Sbjct: 828 PPPQVPSRPNR----APPGVPSRSGQASPSRPESPRP 860


>gi|56549117 dynamin 1 isoform 2 [Homo sapiens]
          Length = 851

 Score = 1343 bits (3475), Expect = 0.0
 Identities = 673/857 (78%), Positives = 759/857 (88%), Gaps = 31/857 (3%)

Query: 1   MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
           MGNRGME+LIPLVN+LQDAFS+IGQ+  LDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG
Sbjct: 1   MGNRGMEDLIPLVNRLQDAFSAIGQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60

Query: 61  SGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPI 120
           SGIVTRRPL+LQL+ + TE+AEFLHCK KKFTDF+EVR EIEAETDRVTGTNKGISPVPI
Sbjct: 61  SGIVTRRPLVLQLVNATTEYAEFLHCKGKKFTDFEEVRLEIEAETDRVTGTNKGISPVPI 120

Query: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD 180
           NLRVYSPHVLNLTL+DLPG+TKVPVGDQPPDIE+QI+DM++QF+++E+ LILAV+PAN D
Sbjct: 121 NLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANSD 180

Query: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240
           LANSDALK+AKEVDPQG RTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK
Sbjct: 181 LANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240

Query: 241 DIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKL 300
           DI+GKKDI AALAAERKFFLSHP+YRH+ADRMGTP+LQK LNQQLTNHIR++LP LR+KL
Sbjct: 241 DIDGKKDITAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQLTNHIRDTLPGLRNKL 300

Query: 301 QSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGA 360
           QSQLLS+EKEVEEYKNFRPDDP RKTKALLQMVQQF VDFEKRIEGSGDQ+DT ELSGGA
Sbjct: 301 QSQLLSIEKEVEEYKNFRPDDPARKTKALLQMVQQFAVDFEKRIEGSGDQIDTYELSGGA 360

Query: 361 RINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAFEAIVKKQIVKL 420
           RINRIFHERFPFELVKMEFDEK+LRREISYAIKNIHG+RTGLFTPDMAFE IVKKQ+ K+
Sbjct: 361 RINRIFHERFPFELVKMEFDEKELRREISYAIKNIHGIRTGLFTPDMAFETIVKKQVKKI 420

Query: 421 KEPSLKCVDLVVSELATVIKKCAEKLSSYPRLREETERIVTTYIREREGRTKDQILLLID 480
           +EP LKCVD+V+SEL + +++C +KL  YPRLREE ERIVTT+IREREGRTK+Q++LLID
Sbjct: 421 REPCLKCVDMVISELISTVRQCTKKLQQYPRLREEMERIVTTHIREREGRTKEQVMLLID 480

Query: 481 IEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQ----VIRRGWLTINNISLMKGGSKE 536
           IE +Y+NTNHEDFIGFANAQQRS Q+NKK+   NQ    VIR+GWLTINNI +MKGGSKE
Sbjct: 481 IELAYMNTNHEDFIGFANAQQRSNQMNKKKTSGNQDEILVIRKGWLTINNIGIMKGGSKE 540

Query: 537 YWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDL 596
           YWFVLTAE+LSWYKD+EEKEKKYML +DNLK+RDVEKGFMS+KH+FA+FNTEQRNVYKD 
Sbjct: 541 YWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDY 600

Query: 597 RQIELACDSQEDVDSWKASFLRAGVYP------EKDQAENEDGAQENTFSMDPQLERQVE 650
           RQ+ELAC++QE+VDSWKASFLRAGVYP      EK     E+G+     SMDPQLERQVE
Sbjct: 601 RQLELACETQEEVDSWKASFLRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVE 660

Query: 651 TIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESAD 710
           TIRNLVDSY+AI+NK++RDLMPKTIMHLMINNTK FI  ELLA LYS  DQ++LMEESA+
Sbjct: 661 TIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELLANLYSCGDQNTLMEESAE 720

Query: 711 QAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSAS--------SHSPT 762
           QAQRRD+MLRMYHALKEAL+IIGDI+T+TVSTP+PPPVDD+WLQ  S        + SPT
Sbjct: 721 QAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPT 780

Query: 763 PQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFP 822
           PQRR  +   PP RP + RGP PGPP    P G+A    APP+PSRPG     A+ D F 
Sbjct: 781 PQRR--APAVPPARPGS-RGPAPGPP----PAGSALG-GAPPVPSRPG-----ASPDPFG 827

Query: 823 APPQIPSRPVRIPPGIP 839
            PPQ+PSRP R PPG+P
Sbjct: 828 PPPQVPSRPNRAPPGVP 844


>gi|171460914 dynamin 1-like isoform 1 [Homo sapiens]
          Length = 736

 Score =  499 bits (1285), Expect = e-141
 Identities = 308/756 (40%), Positives = 445/756 (58%), Gaps = 52/756 (6%)

Query: 6   MEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVT 65
           ME LIP++NKLQD F+++G    + LPQI VVG QS+GKSSVLE+ VGRD LPRG+GIVT
Sbjct: 1   MEALIPVINKLQDVFNTVGADI-IQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVT 59

Query: 66  RRPLILQLIFSKTEH----------------AEFLHCKSKKFTDFDEVRQEIEAETDRVT 109
           RRPLILQL+    E                  +FLH K+K +TDFDE+RQEIE ET+R++
Sbjct: 60  RRPLILQLVHVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIENETERIS 119

Query: 110 GTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESS 169
           G NKG+SP PI+L+++SP+V+NLTL+DLPG+TKVPVGDQP DIE QI+++IL+FIS  +S
Sbjct: 120 GNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNS 179

Query: 170 LILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRR 229
           +ILAVT AN D+A S+ALK+++EVDP G RT+ VITKLDLMD GTDA DVL  +++P++ 
Sbjct: 180 IILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAMDVLMGRVIPVKL 239

Query: 230 GYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHI 289
           G IGVVNRSQ DI  KK +  ++  E  F      Y  +A+R GT +L +TLN+ L +HI
Sbjct: 240 GIIGVVNRSQLDINNKKSVTDSIRDEYAFL--QKKYPSLANRNGTKYLARTLNRLLMHHI 297

Query: 290 RESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGD 349
           R+ LP L++++      L  + +   N   +    K+  LLQ++ +F  ++   IEG+  
Sbjct: 298 RDCLPELKTRIN----VLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNTIEGTAK 353

Query: 350 QVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAF 409
            ++T EL GGARI  IFHE F   L  ++        +I  AI+N  G R  LF P+++F
Sbjct: 354 YIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSF 413

Query: 410 EAIVKKQIVKLKEPSLKCVDLVVSELATVIKKCA----EKLSSYPRLREETERIVTTYIR 465
           E +VK+QI +L+EPSL+CV+LV  E+  +I+ C+    ++L  +P+L +    +VT  +R
Sbjct: 414 ELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLR 473

Query: 466 EREGRTKDQILLLIDIEQSYINTNHEDF---IGFANAQQRSTQLNK-KRAIPNQVIRRGW 521
           +R   T + +  L+ IE +YINT H DF    G  N      + N+  R +P+ V R   
Sbjct: 474 KRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSAVSRDKS 533

Query: 522 LTINNISLMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHV 581
             +   S +   S+E     +AE+      +  +E K +          V++    N   
Sbjct: 534 SKVP--SALAPASQEPSPAASAEADGKLIQDSRRETKNVASGGGGVGDGVQEPTTGN--- 588

Query: 582 FAIFNTEQRNVYKDLRQIE-LACDSQEDVDSWKASFLRAGVYPEKDQAEN-EDGAQENTF 639
                   R + K  +  E LA +  + +    AS       P+K  A N  D       
Sbjct: 589 -------WRGMLKTSKAEELLAEEKSKPIPIMPAS-------PQKGHAVNLLDVPVPVAR 634

Query: 640 SMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSA 699
            +  + +R  E I  L+ SY  I+ K+I+D +PK +MH ++N+ K  +  EL+  LY S+
Sbjct: 635 KLSAREQRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSS 694

Query: 700 DQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDI 735
               L+ ES D AQRR +   M  AL+ A  II +I
Sbjct: 695 LLDDLLTESEDMAQRRKEAADMLKALQGASQIIAEI 730


>gi|171460918 dynamin 1-like isoform 3 [Homo sapiens]
          Length = 699

 Score =  452 bits (1164), Expect = e-127
 Identities = 251/537 (46%), Positives = 353/537 (65%), Gaps = 31/537 (5%)

Query: 6   MEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVT 65
           ME LIP++NKLQD F+++G    + LPQI VVG QS+GKSSVLE+ VGRD LPRG+GIVT
Sbjct: 1   MEALIPVINKLQDVFNTVGADI-IQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVT 59

Query: 66  RRPLILQLIFSKTEH----------------AEFLHCKSKKFTDFDEVRQEIEAETDRVT 109
           RRPLILQL+    E                  +FLH K+K +TDFDE+RQEIE ET+R++
Sbjct: 60  RRPLILQLVHVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIENETERIS 119

Query: 110 GTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESS 169
           G NKG+SP PI+L+++SP+V+NLTL+DLPG+TKVPVGDQP DIE QI+++IL+FIS  +S
Sbjct: 120 GNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNS 179

Query: 170 LILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRR 229
           +ILAVT AN D+A S+ALK+++EVDP G RT+ VITKLDLMD GTDA DVL  +++P++ 
Sbjct: 180 IILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAMDVLMGRVIPVKL 239

Query: 230 GYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHI 289
           G IGVVNRSQ DI  KK +  ++  E  F      Y  +A+R GT +L +TLN+ L +HI
Sbjct: 240 GIIGVVNRSQLDINNKKSVTDSIRDEYAFL--QKKYPSLANRNGTKYLARTLNRLLMHHI 297

Query: 290 RESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGD 349
           R+ LP L++++      L  + +   N   +    K+  LLQ++ +F  ++   IEG+  
Sbjct: 298 RDCLPELKTRIN----VLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNTIEGTAK 353

Query: 350 QVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAF 409
            ++T EL GGARI  IFHE F   L  ++        +I  AI+N  G R  LF P+++F
Sbjct: 354 YIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSF 413

Query: 410 EAIVKKQIVKLKEPSLKCVDLVVSELATVIKKCA----EKLSSYPRLREETERIVTTYIR 465
           E +VK+QI +L+EPSL+CV+LV  E+  +I+ C+    ++L  +P+L +    +VT  +R
Sbjct: 414 ELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLR 473

Query: 466 EREGRTKDQILLLIDIEQSYINTNHEDF---IGFANAQQRSTQLNK-KRAIPNQVIR 518
           +R   T + +  L+ IE +YINT H DF    G  N      + N+  R +P+ V R
Sbjct: 474 KRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSAVSR 530



 Score = 72.0 bits (175), Expect = 2e-12
 Identities = 36/90 (40%), Positives = 53/90 (58%)

Query: 646 ERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLM 705
           +R  E I  L+ SY  I+ K+I+D +PK +MH ++N+ K  +  EL+  LY S+    L+
Sbjct: 604 QRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLL 663

Query: 706 EESADQAQRRDDMLRMYHALKEALNIIGDI 735
            ES D AQRR +   M  AL+ A  II +I
Sbjct: 664 TESEDMAQRRKEAADMLKALQGASQIIAEI 693


>gi|171460916 dynamin 1-like isoform 2 [Homo sapiens]
          Length = 710

 Score =  452 bits (1164), Expect = e-127
 Identities = 251/537 (46%), Positives = 353/537 (65%), Gaps = 31/537 (5%)

Query: 6   MEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVT 65
           ME LIP++NKLQD F+++G    + LPQI VVG QS+GKSSVLE+ VGRD LPRG+GIVT
Sbjct: 1   MEALIPVINKLQDVFNTVGADI-IQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVT 59

Query: 66  RRPLILQLIFSKTEH----------------AEFLHCKSKKFTDFDEVRQEIEAETDRVT 109
           RRPLILQL+    E                  +FLH K+K +TDFDE+RQEIE ET+R++
Sbjct: 60  RRPLILQLVHVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIENETERIS 119

Query: 110 GTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESS 169
           G NKG+SP PI+L+++SP+V+NLTL+DLPG+TKVPVGDQP DIE QI+++IL+FIS  +S
Sbjct: 120 GNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNS 179

Query: 170 LILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRR 229
           +ILAVT AN D+A S+ALK+++EVDP G RT+ VITKLDLMD GTDA DVL  +++P++ 
Sbjct: 180 IILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAMDVLMGRVIPVKL 239

Query: 230 GYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHI 289
           G IGVVNRSQ DI  KK +  ++  E  F      Y  +A+R GT +L +TLN+ L +HI
Sbjct: 240 GIIGVVNRSQLDINNKKSVTDSIRDEYAFL--QKKYPSLANRNGTKYLARTLNRLLMHHI 297

Query: 290 RESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGD 349
           R+ LP L++++      L  + +   N   +    K+  LLQ++ +F  ++   IEG+  
Sbjct: 298 RDCLPELKTRIN----VLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNTIEGTAK 353

Query: 350 QVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAF 409
            ++T EL GGARI  IFHE F   L  ++        +I  AI+N  G R  LF P+++F
Sbjct: 354 YIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSF 413

Query: 410 EAIVKKQIVKLKEPSLKCVDLVVSELATVIKKCA----EKLSSYPRLREETERIVTTYIR 465
           E +VK+QI +L+EPSL+CV+LV  E+  +I+ C+    ++L  +P+L +    +VT  +R
Sbjct: 414 ELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLR 473

Query: 466 EREGRTKDQILLLIDIEQSYINTNHEDF---IGFANAQQRSTQLNK-KRAIPNQVIR 518
           +R   T + +  L+ IE +YINT H DF    G  N      + N+  R +P+ V R
Sbjct: 474 KRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSAVSR 530



 Score = 72.0 bits (175), Expect = 2e-12
 Identities = 36/90 (40%), Positives = 53/90 (58%)

Query: 646 ERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLM 705
           +R  E I  L+ SY  I+ K+I+D +PK +MH ++N+ K  +  EL+  LY S+    L+
Sbjct: 615 QRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLL 674

Query: 706 EESADQAQRRDDMLRMYHALKEALNIIGDI 735
            ES D AQRR +   M  AL+ A  II +I
Sbjct: 675 TESEDMAQRRKEAADMLKALQGASQIIAEI 704


>gi|222136619 myxovirus resistance protein 1 [Homo sapiens]
          Length = 662

 Score =  239 bits (609), Expect = 1e-62
 Identities = 158/435 (36%), Positives = 245/435 (56%), Gaps = 15/435 (3%)

Query: 7   EELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTR 66
           E++ P ++ L D+  ++G    L LP IAV+G QS+GKSSVLE   G   LPRGSGIVTR
Sbjct: 47  EKVRPCID-LIDSLRALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVA-LPRGSGIVTR 104

Query: 67  RPLILQLIFSKTEHAEFLHCKSK------KFTDFDEVRQEIEAETDRVTGTNKGISPVPI 120
            PL+L+L   K  + +    K        + +D  EV +EI    + + G   GIS   I
Sbjct: 105 CPLVLKL--KKLVNEDKWRGKVSYQDYEIEISDASEVEKEINKAQNAIAGEGMGISHELI 162

Query: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD 180
            L + S  V +LTLIDLPGIT+V VG+QP DI Y+IK +I ++I R+ ++ L V P+N+D
Sbjct: 163 TLEISSRDVPDLTLIDLPGITRVAVGNQPADIGYKIKTLIKKYIQRQETISLVVVPSNVD 222

Query: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDAR--DVLENKLLPLRRGYIGVVNRS 238
           +A ++AL +A+EVDP+G RTIG++TK DL+D+GT+ +  DV+ N +  L++GY+ V  R 
Sbjct: 223 IATTEALSMAQEVDPEGDRTIGILTKPDLVDKGTEDKVVDVVRNLVFHLKKGYMIVKCRG 282

Query: 239 QKDIEGKKDIRAALAAERKFFLSHPAYRHMAD--RMGTPHLQKTLNQQLTNHIRESLPAL 296
           Q++I+ +  +  AL  E+ FF +HP +R + +  +   P L + L  +L  HI +SLP L
Sbjct: 283 QQEIQDQLSLSEALQREKIFFENHPYFRDLLEEGKATVPCLAEKLTSELITHICKSLPLL 342

Query: 297 RSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLEL 356
            ++++     + +E+++Y    P+D   K   L+  V  F  D    ++G  + V   ++
Sbjct: 343 ENQIKETHQRITEELQKYGVDIPEDENEKMFFLIDKVNAFNQDITALMQGE-ETVGEEDI 401

Query: 357 SGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAFEAIVKKQ 416
               R+   FH+         +   K L R+I        G     F     FE IVK+Q
Sbjct: 402 RLFTRLRHEFHKWSTIIENNFQEGHKILSRKIQKFENQYRGRELPGFVNYRTFETIVKQQ 461

Query: 417 IVKLKEPSLKCVDLV 431
           I  L+EP++  +  V
Sbjct: 462 IKALEEPAVDMLHTV 476


>gi|222136617 myxovirus resistance protein 1 [Homo sapiens]
          Length = 662

 Score =  239 bits (609), Expect = 1e-62
 Identities = 158/435 (36%), Positives = 245/435 (56%), Gaps = 15/435 (3%)

Query: 7   EELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTR 66
           E++ P ++ L D+  ++G    L LP IAV+G QS+GKSSVLE   G   LPRGSGIVTR
Sbjct: 47  EKVRPCID-LIDSLRALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVA-LPRGSGIVTR 104

Query: 67  RPLILQLIFSKTEHAEFLHCKSK------KFTDFDEVRQEIEAETDRVTGTNKGISPVPI 120
            PL+L+L   K  + +    K        + +D  EV +EI    + + G   GIS   I
Sbjct: 105 CPLVLKL--KKLVNEDKWRGKVSYQDYEIEISDASEVEKEINKAQNAIAGEGMGISHELI 162

Query: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD 180
            L + S  V +LTLIDLPGIT+V VG+QP DI Y+IK +I ++I R+ ++ L V P+N+D
Sbjct: 163 TLEISSRDVPDLTLIDLPGITRVAVGNQPADIGYKIKTLIKKYIQRQETISLVVVPSNVD 222

Query: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDAR--DVLENKLLPLRRGYIGVVNRS 238
           +A ++AL +A+EVDP+G RTIG++TK DL+D+GT+ +  DV+ N +  L++GY+ V  R 
Sbjct: 223 IATTEALSMAQEVDPEGDRTIGILTKPDLVDKGTEDKVVDVVRNLVFHLKKGYMIVKCRG 282

Query: 239 QKDIEGKKDIRAALAAERKFFLSHPAYRHMAD--RMGTPHLQKTLNQQLTNHIRESLPAL 296
           Q++I+ +  +  AL  E+ FF +HP +R + +  +   P L + L  +L  HI +SLP L
Sbjct: 283 QQEIQDQLSLSEALQREKIFFENHPYFRDLLEEGKATVPCLAEKLTSELITHICKSLPLL 342

Query: 297 RSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLEL 356
            ++++     + +E+++Y    P+D   K   L+  V  F  D    ++G  + V   ++
Sbjct: 343 ENQIKETHQRITEELQKYGVDIPEDENEKMFFLIDKVNAFNQDITALMQGE-ETVGEEDI 401

Query: 357 SGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAFEAIVKKQ 416
               R+   FH+         +   K L R+I        G     F     FE IVK+Q
Sbjct: 402 RLFTRLRHEFHKWSTIIENNFQEGHKILSRKIQKFENQYRGRELPGFVNYRTFETIVKQQ 461

Query: 417 IVKLKEPSLKCVDLV 431
           I  L+EP++  +  V
Sbjct: 462 IKALEEPAVDMLHTV 476


>gi|11342664 myxovirus resistance protein 2 [Homo sapiens]
          Length = 715

 Score =  223 bits (568), Expect = 6e-58
 Identities = 158/440 (35%), Positives = 237/440 (53%), Gaps = 19/440 (4%)

Query: 16  LQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLIF 75
           L D+  ++G    L LP IAV+G QS+GKSSVLE   G   LPRGSGIVTR PL+L+L  
Sbjct: 103 LIDSLRALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVA-LPRGSGIVTRCPLVLKLKK 161

Query: 76  SKTEH-AEFLHCKSKKFT--DFDEVRQEIEAETDRVTGTNKGISPVPINLRVYSPHVLNL 132
              E  A  +  ++ +    D  +V +EI    + + G  +GIS   I+L + SP V +L
Sbjct: 162 QPCEAWAGRISYRNTELELQDPGQVEKEIHKAQNVMAGNGRGISHELISLEITSPEVPDL 221

Query: 133 TLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMDLANSDALKLAKE 192
           T+IDLPGIT+V V +QP DI  QIK +I ++I R+ ++ L V P N+D+A ++AL +A E
Sbjct: 222 TIIDLPGITRVAVDNQPRDIGLQIKALIKKYIQRQQTINLVVVPCNVDIATTEALSMAHE 281

Query: 193 VDPQGLRTIGVITKLDLMDEGTD--ARDVLENKLLPLRRGYIGVVNRSQKDIEGKKDIRA 250
           VDP+G RTIG++TK DLMD GT+    +V+ N   PL++GY+ V  R Q++I  +  +  
Sbjct: 282 VDPEGDRTIGILTKPDLMDRGTEKSVMNVVRNLTYPLKKGYMIVKCRGQQEITNRLSLAE 341

Query: 251 ALAAERKFFLSHPAYRHMADR--MGTPHLQKTLNQQLTNHIRESLPALRSKLQSQLLSLE 308
           A   E  FF +HP +R + +      P L + L  +L  HI++SLP L  +++    S +
Sbjct: 342 ATKKEITFFQTHPYFRVLLEEGSATVPRLAERLTTELIMHIQKSLPLLEGQIRE---SHQ 398

Query: 309 KEVEEYKNFRPDDPTR---KTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGARINRI 365
           K  EE +    D P++   K   L++ ++ F  D EK +EG  + V   E     +I   
Sbjct: 399 KATEELRRCGADIPSQEADKMFFLIEKIKMFNQDIEKLVEGE-EVVRENETRLYNKIRED 457

Query: 366 FHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAFEAIVKKQIVKLKEPSL 425
           F           +  +  +  E+    K   G     F     FE IV + I +L EP+L
Sbjct: 458 FKNWVGILATNTQKVKNIIHEEVEKYEKQYRGKELLGFVNYKTFEIIVHQYIQQLVEPAL 517

Query: 426 ----KCVDLVVSELATVIKK 441
               K ++++      V KK
Sbjct: 518 SMLQKAMEIIQQAFINVAKK 537


>gi|239756350 PREDICTED: UPF0621 protein C-like [Homo sapiens]
          Length = 135

 Score =  122 bits (305), Expect = 2e-27
 Identities = 67/125 (53%), Positives = 86/125 (68%), Gaps = 4/125 (3%)

Query: 623 PEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLM----PKTIMHL 678
           P +     E+G+     SMDPQL  Q+ET ++LVDSYVAI+NK++ DLM    PKT MHL
Sbjct: 6   PWQASKAEENGSDSFMHSMDPQLVWQMETTQSLVDSYVAIVNKTVWDLMVGLTPKTTMHL 65

Query: 679 MINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTS 738
           MINN   FI  ELLA LYS  D++ LME+S +QA+  ++ L M+H L+EA NIIGDI T+
Sbjct: 66  MINNMHEFIFSELLAKLYSCGDENMLMEDSTEQAKWCNETLCMHHVLREAPNIIGDIKTT 125

Query: 739 TVSTP 743
            VS P
Sbjct: 126 MVSMP 130


>gi|239750876 PREDICTED: UPF0621 protein C-like [Homo sapiens]
          Length = 135

 Score =  122 bits (305), Expect = 2e-27
 Identities = 67/125 (53%), Positives = 86/125 (68%), Gaps = 4/125 (3%)

Query: 623 PEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLM----PKTIMHL 678
           P +     E+G+     SMDPQL  Q+ET ++LVDSYVAI+NK++ DLM    PKT MHL
Sbjct: 6   PWQASKAEENGSDSFMHSMDPQLVWQMETTQSLVDSYVAIVNKTVWDLMVGLTPKTTMHL 65

Query: 679 MINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTS 738
           MINN   FI  ELLA LYS  D++ LME+S +QA+  ++ L M+H L+EA NIIGDI T+
Sbjct: 66  MINNMHEFIFSELLAKLYSCGDENMLMEDSTEQAKWCNETLCMHHVLREAPNIIGDIKTT 125

Query: 739 TVSTP 743
            VS P
Sbjct: 126 MVSMP 130


>gi|169208224 PREDICTED: UPF0621 protein C-like [Homo sapiens]
          Length = 155

 Score =  122 bits (305), Expect = 2e-27
 Identities = 67/125 (53%), Positives = 86/125 (68%), Gaps = 4/125 (3%)

Query: 623 PEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLM----PKTIMHL 678
           P +     E+G+     SMDPQL  Q+ET ++LVDSYVAI+NK++ DLM    PKT MHL
Sbjct: 26  PWQASKAEENGSDSFMHSMDPQLVWQMETTQSLVDSYVAIVNKTVWDLMVGLTPKTTMHL 85

Query: 679 MINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTS 738
           MINN   FI  ELLA LYS  D++ LME+S +QA+  ++ L M+H L+EA NIIGDI T+
Sbjct: 86  MINNMHEFIFSELLAKLYSCGDENMLMEDSTEQAKWCNETLCMHHVLREAPNIIGDIKTT 145

Query: 739 TVSTP 743
            VS P
Sbjct: 146 MVSMP 150


>gi|224831253 optic atrophy 1 isoform 8 [Homo sapiens]
          Length = 1015

 Score =  114 bits (285), Expect = 4e-25
 Identities = 89/328 (27%), Positives = 147/328 (44%), Gaps = 21/328 (6%)

Query: 7   EELIPLVNKLQDAFSSIGQSCHLD--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIV 64
           + LI + +++ D  S    S +    LP++ VVG QSAGK+SVLE        PRGSG +
Sbjct: 317 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 376

Query: 65  TRRPLILQLIFSKTEHAEFLHCKSKKFT-----DFDEVRQEIEAETDRVTGTNKGISPVP 119
             R  +   +     H       S++F      D   +R EIE    +       +SP  
Sbjct: 377 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 436

Query: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANM 179
           I+L V  P +  + L+DLPG+         PD +  I  +   ++   +++IL +   ++
Sbjct: 437 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 496

Query: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYIGV 234
           D   S    L  ++DP G RTI V+TK+DL ++   +    + ++E KL P++  GY  V
Sbjct: 497 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 556

Query: 235 VNRSQKDIEGKKDIRAALAAERKFFLSHPAYRH---MADRMGTPHLQKTLNQQLTNHIRE 291
           V       E    I A    E +FF +    +     A ++ T +L   ++      +RE
Sbjct: 557 VTGKGNSSE---SIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 613

Query: 292 SLPALRSKLQSQLLSLEKEVEEYKNFRP 319
           S+       ++   +LE    E+KN  P
Sbjct: 614 SVEQQADSFKATRFNLE---TEWKNNYP 638


>gi|224831251 optic atrophy 1 isoform 7 [Homo sapiens]
          Length = 997

 Score =  114 bits (285), Expect = 4e-25
 Identities = 89/328 (27%), Positives = 147/328 (44%), Gaps = 21/328 (6%)

Query: 7   EELIPLVNKLQDAFSSIGQSCHLD--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIV 64
           + LI + +++ D  S    S +    LP++ VVG QSAGK+SVLE        PRGSG +
Sbjct: 299 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 358

Query: 65  TRRPLILQLIFSKTEHAEFLHCKSKKFT-----DFDEVRQEIEAETDRVTGTNKGISPVP 119
             R  +   +     H       S++F      D   +R EIE    +       +SP  
Sbjct: 359 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 418

Query: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANM 179
           I+L V  P +  + L+DLPG+         PD +  I  +   ++   +++IL +   ++
Sbjct: 419 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 478

Query: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYIGV 234
           D   S    L  ++DP G RTI V+TK+DL ++   +    + ++E KL P++  GY  V
Sbjct: 479 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 538

Query: 235 VNRSQKDIEGKKDIRAALAAERKFFLSHPAYRH---MADRMGTPHLQKTLNQQLTNHIRE 291
           V       E    I A    E +FF +    +     A ++ T +L   ++      +RE
Sbjct: 539 VTGKGNSSE---SIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 595

Query: 292 SLPALRSKLQSQLLSLEKEVEEYKNFRP 319
           S+       ++   +LE    E+KN  P
Sbjct: 596 SVEQQADSFKATRFNLE---TEWKNNYP 620


>gi|18860841 optic atrophy 1 isoform 6 [Homo sapiens]
          Length = 979

 Score =  114 bits (285), Expect = 4e-25
 Identities = 89/328 (27%), Positives = 147/328 (44%), Gaps = 21/328 (6%)

Query: 7   EELIPLVNKLQDAFSSIGQSCHLD--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIV 64
           + LI + +++ D  S    S +    LP++ VVG QSAGK+SVLE        PRGSG +
Sbjct: 281 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 340

Query: 65  TRRPLILQLIFSKTEHAEFLHCKSKKFT-----DFDEVRQEIEAETDRVTGTNKGISPVP 119
             R  +   +     H       S++F      D   +R EIE    +       +SP  
Sbjct: 341 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 400

Query: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANM 179
           I+L V  P +  + L+DLPG+         PD +  I  +   ++   +++IL +   ++
Sbjct: 401 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 460

Query: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYIGV 234
           D   S    L  ++DP G RTI V+TK+DL ++   +    + ++E KL P++  GY  V
Sbjct: 461 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 520

Query: 235 VNRSQKDIEGKKDIRAALAAERKFFLSHPAYRH---MADRMGTPHLQKTLNQQLTNHIRE 291
           V       E    I A    E +FF +    +     A ++ T +L   ++      +RE
Sbjct: 521 VTGKGNSSE---SIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 577

Query: 292 SLPALRSKLQSQLLSLEKEVEEYKNFRP 319
           S+       ++   +LE    E+KN  P
Sbjct: 578 SVEQQADSFKATRFNLE---TEWKNNYP 602


>gi|224831248 optic atrophy 1 isoform 5 [Homo sapiens]
          Length = 978

 Score =  114 bits (285), Expect = 4e-25
 Identities = 89/328 (27%), Positives = 147/328 (44%), Gaps = 21/328 (6%)

Query: 7   EELIPLVNKLQDAFSSIGQSCHLD--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIV 64
           + LI + +++ D  S    S +    LP++ VVG QSAGK+SVLE        PRGSG +
Sbjct: 280 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 339

Query: 65  TRRPLILQLIFSKTEHAEFLHCKSKKFT-----DFDEVRQEIEAETDRVTGTNKGISPVP 119
             R  +   +     H       S++F      D   +R EIE    +       +SP  
Sbjct: 340 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 399

Query: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANM 179
           I+L V  P +  + L+DLPG+         PD +  I  +   ++   +++IL +   ++
Sbjct: 400 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 459

Query: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYIGV 234
           D   S    L  ++DP G RTI V+TK+DL ++   +    + ++E KL P++  GY  V
Sbjct: 460 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 519

Query: 235 VNRSQKDIEGKKDIRAALAAERKFFLSHPAYRH---MADRMGTPHLQKTLNQQLTNHIRE 291
           V       E    I A    E +FF +    +     A ++ T +L   ++      +RE
Sbjct: 520 VTGKGNSSE---SIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 576

Query: 292 SLPALRSKLQSQLLSLEKEVEEYKNFRP 319
           S+       ++   +LE    E+KN  P
Sbjct: 577 SVEQQADSFKATRFNLE---TEWKNNYP 601


>gi|18860835 optic atrophy 1 isoform 4 [Homo sapiens]
          Length = 961

 Score =  114 bits (285), Expect = 4e-25
 Identities = 89/328 (27%), Positives = 147/328 (44%), Gaps = 21/328 (6%)

Query: 7   EELIPLVNKLQDAFSSIGQSCHLD--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIV 64
           + LI + +++ D  S    S +    LP++ VVG QSAGK+SVLE        PRGSG +
Sbjct: 263 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 322

Query: 65  TRRPLILQLIFSKTEHAEFLHCKSKKFT-----DFDEVRQEIEAETDRVTGTNKGISPVP 119
             R  +   +     H       S++F      D   +R EIE    +       +SP  
Sbjct: 323 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 382

Query: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANM 179
           I+L V  P +  + L+DLPG+         PD +  I  +   ++   +++IL +   ++
Sbjct: 383 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 442

Query: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYIGV 234
           D   S    L  ++DP G RTI V+TK+DL ++   +    + ++E KL P++  GY  V
Sbjct: 443 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 502

Query: 235 VNRSQKDIEGKKDIRAALAAERKFFLSHPAYRH---MADRMGTPHLQKTLNQQLTNHIRE 291
           V       E    I A    E +FF +    +     A ++ T +L   ++      +RE
Sbjct: 503 VTGKGNSSE---SIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 559

Query: 292 SLPALRSKLQSQLLSLEKEVEEYKNFRP 319
           S+       ++   +LE    E+KN  P
Sbjct: 560 SVEQQADSFKATRFNLE---TEWKNNYP 584


>gi|18860833 optic atrophy 1 isoform 3 [Homo sapiens]
          Length = 942

 Score =  114 bits (285), Expect = 4e-25
 Identities = 89/328 (27%), Positives = 147/328 (44%), Gaps = 21/328 (6%)

Query: 7   EELIPLVNKLQDAFSSIGQSCHLD--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIV 64
           + LI + +++ D  S    S +    LP++ VVG QSAGK+SVLE        PRGSG +
Sbjct: 244 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 303

Query: 65  TRRPLILQLIFSKTEHAEFLHCKSKKFT-----DFDEVRQEIEAETDRVTGTNKGISPVP 119
             R  +   +     H       S++F      D   +R EIE    +       +SP  
Sbjct: 304 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 363

Query: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANM 179
           I+L V  P +  + L+DLPG+         PD +  I  +   ++   +++IL +   ++
Sbjct: 364 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 423

Query: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYIGV 234
           D   S    L  ++DP G RTI V+TK+DL ++   +    + ++E KL P++  GY  V
Sbjct: 424 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 483

Query: 235 VNRSQKDIEGKKDIRAALAAERKFFLSHPAYRH---MADRMGTPHLQKTLNQQLTNHIRE 291
           V       E    I A    E +FF +    +     A ++ T +L   ++      +RE
Sbjct: 484 VTGKGNSSE---SIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 540

Query: 292 SLPALRSKLQSQLLSLEKEVEEYKNFRP 319
           S+       ++   +LE    E+KN  P
Sbjct: 541 SVEQQADSFKATRFNLE---TEWKNNYP 565


>gi|18860831 optic atrophy 1 isoform 2 [Homo sapiens]
          Length = 924

 Score =  114 bits (285), Expect = 4e-25
 Identities = 89/328 (27%), Positives = 147/328 (44%), Gaps = 21/328 (6%)

Query: 7   EELIPLVNKLQDAFSSIGQSCHLD--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIV 64
           + LI + +++ D  S    S +    LP++ VVG QSAGK+SVLE        PRGSG +
Sbjct: 226 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 285

Query: 65  TRRPLILQLIFSKTEHAEFLHCKSKKFT-----DFDEVRQEIEAETDRVTGTNKGISPVP 119
             R  +   +     H       S++F      D   +R EIE    +       +SP  
Sbjct: 286 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 345

Query: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANM 179
           I+L V  P +  + L+DLPG+         PD +  I  +   ++   +++IL +   ++
Sbjct: 346 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 405

Query: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYIGV 234
           D   S    L  ++DP G RTI V+TK+DL ++   +    + ++E KL P++  GY  V
Sbjct: 406 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 465

Query: 235 VNRSQKDIEGKKDIRAALAAERKFFLSHPAYRH---MADRMGTPHLQKTLNQQLTNHIRE 291
           V       E    I A    E +FF +    +     A ++ T +L   ++      +RE
Sbjct: 466 VTGKGNSSE---SIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 522

Query: 292 SLPALRSKLQSQLLSLEKEVEEYKNFRP 319
           S+       ++   +LE    E+KN  P
Sbjct: 523 SVEQQADSFKATRFNLE---TEWKNNYP 547


>gi|224831243 optic atrophy 1 isoform 1 [Homo sapiens]
          Length = 960

 Score =  114 bits (285), Expect = 4e-25
 Identities = 89/328 (27%), Positives = 147/328 (44%), Gaps = 21/328 (6%)

Query: 7   EELIPLVNKLQDAFSSIGQSCHLD--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIV 64
           + LI + +++ D  S    S +    LP++ VVG QSAGK+SVLE        PRGSG +
Sbjct: 262 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 321

Query: 65  TRRPLILQLIFSKTEHAEFLHCKSKKFT-----DFDEVRQEIEAETDRVTGTNKGISPVP 119
             R  +   +     H       S++F      D   +R EIE    +       +SP  
Sbjct: 322 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 381

Query: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANM 179
           I+L V  P +  + L+DLPG+         PD +  I  +   ++   +++IL +   ++
Sbjct: 382 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 441

Query: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYIGV 234
           D   S    L  ++DP G RTI V+TK+DL ++   +    + ++E KL P++  GY  V
Sbjct: 442 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 501

Query: 235 VNRSQKDIEGKKDIRAALAAERKFFLSHPAYRH---MADRMGTPHLQKTLNQQLTNHIRE 291
           V       E    I A    E +FF +    +     A ++ T +L   ++      +RE
Sbjct: 502 VTGKGNSSE---SIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 558

Query: 292 SLPALRSKLQSQLLSLEKEVEEYKNFRP 319
           S+       ++   +LE    E+KN  P
Sbjct: 559 SVEQQADSFKATRFNLE---TEWKNNYP 583


>gi|113425405 PREDICTED: similar to dynamin 1 [Homo sapiens]
          Length = 105

 Score = 90.9 bits (224), Expect = 5e-18
 Identities = 49/97 (50%), Positives = 66/97 (68%), Gaps = 13/97 (13%)

Query: 695 LYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQ 754
           +YS  +Q++LMEE A+QAQ+ D+ML M+HALKEAL+IIGDI+ +TV+ P+PPPVDDTWLQ
Sbjct: 1   MYSCGNQNTLMEELAEQAQQHDEMLHMHHALKEALSIIGDINRTTVTMPMPPPVDDTWLQ 60

Query: 755 SAS---SH-----SPTPQRRPV-----SSIHPPGRPP 778
             S   +H      PT  + P      S++   G PP
Sbjct: 61  VQSIPDAHRYQRLPPTAPKSPTRDAQRSALGASGTPP 97


>gi|239745270 PREDICTED: hypothetical protein XP_002343416 [Homo
           sapiens]
          Length = 63

 Score = 87.8 bits (216), Expect = 4e-17
 Identities = 39/59 (66%), Positives = 52/59 (88%)

Query: 695 LYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWL 753
           +YS  +Q++LMEE A+QAQ+ D+ML M+HALKEAL+IIGDI+ +TV+ P+PPPVDDTWL
Sbjct: 1   MYSCGNQNTLMEELAEQAQQHDEMLHMHHALKEALSIIGDINRTTVTMPMPPPVDDTWL 59


>gi|239745262 PREDICTED: hypothetical protein XP_002343372 [Homo
           sapiens]
          Length = 63

 Score = 87.8 bits (216), Expect = 4e-17
 Identities = 39/59 (66%), Positives = 52/59 (88%)

Query: 695 LYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWL 753
           +YS  +Q++LMEE A+QAQ+ D+ML M+HALKEAL+IIGDI+ +TV+ P+PPPVDDTWL
Sbjct: 1   MYSCGNQNTLMEELAEQAQQHDEMLHMHHALKEALSIIGDINRTTVTMPMPPPVDDTWL 59


>gi|239745286 PREDICTED: hypothetical protein XP_002343417 [Homo
           sapiens]
          Length = 103

 Score = 83.6 bits (205), Expect = 7e-16
 Identities = 48/97 (49%), Positives = 65/97 (67%), Gaps = 15/97 (15%)

Query: 695 LYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQ 754
           +YS  +Q++LMEE A+QAQ+ D+ML M+HALKEAL+IIGDI+ +TV+  +PPPVDDTWLQ
Sbjct: 1   MYSCGNQNTLMEELAEQAQQHDEMLHMHHALKEALSIIGDINRTTVT--MPPPVDDTWLQ 58

Query: 755 SAS---SH-----SPTPQRRPV-----SSIHPPGRPP 778
             S   +H      PT  + P      S++   G PP
Sbjct: 59  VQSIPDAHRYQRLPPTAPKSPTRDAQRSALGTSGTPP 95


>gi|7706501 WW domain binding protein 11 [Homo sapiens]
          Length = 641

 Score = 58.5 bits (140), Expect = 3e-08
 Identities = 45/130 (34%), Positives = 52/130 (40%), Gaps = 16/130 (12%)

Query: 749 DDTWLQSASSHSPTPQRRPVSSIHPPGRP-PAVRGPTPGPPLIPV----------PVGAA 797
           D T   S+   +P PQ  P S I  P  P P   GP P PPL P           P GA 
Sbjct: 381 DGTSTASSQQQAP-PQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAP 439

Query: 798 ASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPPGVPSRRPP--AAPSRPT 855
                P +P   GP          P P + P  P   PPG+PPG P R PP    P  P 
Sbjct: 440 PFLRPPGMPGLRGPLPRLLPPG--PPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPP 497

Query: 856 IIRPAEPSLL 865
            I P  P ++
Sbjct: 498 GIPPPRPGMM 507



 Score = 53.5 bits (127), Expect = 8e-07
 Identities = 47/160 (29%), Positives = 65/160 (40%), Gaps = 19/160 (11%)

Query: 706 EESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQR 765
           E+ +D ++      + +   KE  +  G  + S+     P  V  + +Q+     P P  
Sbjct: 358 EDDSDDSEAEKQSQKQH---KEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLG 414

Query: 766 RPVSS-IHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAP 824
            P +  + PPG PP    P P       P GA      P +P   GP        L P P
Sbjct: 415 PPPAPPLRPPG-PPTGLPPGP-------PPGAPPFLRPPGMPGLRGPLPRL----LPPGP 462

Query: 825 PQIPSRPVRIPPGIPPGVPSRRPPAAPSRPTIIRPAEPSL 864
           P  P RP   PPG PPG+P   PP  P  P +  PA P +
Sbjct: 463 P--PGRPPGPPPGPPPGLPPGPPPRGPP-PRLPPPAPPGI 499



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 38/120 (31%), Positives = 47/120 (39%), Gaps = 13/120 (10%)

Query: 743 PVPPPVDDTWLQSASS---HSPTPQRRPVSSIHPPGRPPAVR-GPTPGPPLIPVPVGAAA 798
           P PPP    +L+         P P+  P     PPGRPP    GP PG P  P P G   
Sbjct: 432 PGPPPGAPPFLRPPGMPGLRGPLPRLLPPGP--PPGRPPGPPPGPPPGLPPGPPPRGPPP 489

Query: 799 SFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPPGVPSRRPPAAPSRPTIIR 858
               P  P  P P+       L   PP  P+     PPG+ P  P   P    + P +I+
Sbjct: 490 RLPPPAPPGIPPPRPGMMRPPL--VPPLGPA-----PPGLFPPAPLPNPGVLSAPPNLIQ 542



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 32/93 (34%), Positives = 37/93 (39%), Gaps = 12/93 (12%)

Query: 743 PVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVP-VGAAASFS 801
           P PPP             P P   P     PP R P  R P P PP IP P  G      
Sbjct: 460 PGPPP--------GRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPL 511

Query: 802 APPI-PSRPG--PQSVFANSDLFPAPPQIPSRP 831
            PP+ P+ PG  P +   N  +  APP +  RP
Sbjct: 512 VPPLGPAPPGLFPPAPLPNPGVLSAPPNLIQRP 544


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.135    0.388 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,926,752
Number of Sequences: 37866
Number of extensions: 1969893
Number of successful extensions: 21262
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 259
Number of HSP's successfully gapped in prelim test: 1101
Number of HSP's that attempted gapping in prelim test: 11795
Number of HSP's gapped (non-prelim): 6142
length of query: 866
length of database: 18,247,518
effective HSP length: 111
effective length of query: 755
effective length of database: 14,044,392
effective search space: 10603515960
effective search space used: 10603515960
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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