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Search of human proteins with 56237027
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|56237027 insulin-like growth factor 2 mRNA binding protein 1
isoform 1 [Homo sapiens]
(577 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|56237027 insulin-like growth factor 2 mRNA binding protein 1 ... 1136 0.0
gi|30795212 insulin-like growth factor 2 mRNA binding protein 3 ... 843 0.0
gi|64085377 insulin-like growth factor 2 mRNA binding protein 2 ... 777 0.0
gi|56118219 insulin-like growth factor 2 mRNA binding protein 2 ... 744 0.0
gi|238624257 insulin-like growth factor 2 mRNA binding protein 1... 601 e-172
gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens] 83 6e-16
gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens] 77 3e-14
gi|100816392 far upstream element (FUSE) binding protein 3 [Homo... 75 2e-13
gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens] 74 4e-13
gi|222352151 poly(rC) binding protein 1 [Homo sapiens] 73 6e-13
gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens] 72 1e-12
gi|14670373 poly(rC) binding protein 4 isoform c [Homo sapiens] 72 2e-12
gi|14670369 poly(rC) binding protein 4 isoform c [Homo sapiens] 72 2e-12
gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens] 70 4e-12
gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens] 70 4e-12
gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens] 70 4e-12
gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens] 70 4e-12
gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens] 70 4e-12
gi|154355000 KH-type splicing regulatory protein [Homo sapiens] 69 9e-12
gi|17402900 far upstream element-binding protein [Homo sapiens] 68 2e-11
gi|56549653 neuro-oncological ventral antigen 1 isoform 1 [Homo ... 67 4e-11
gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo ... 61 2e-09
gi|4885409 high density lipoprotein binding protein [Homo sapiens] 60 5e-09
gi|42716280 high density lipoprotein binding protein [Homo sapiens] 60 5e-09
gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens] 59 9e-09
gi|145312259 tudor and KH domain containing isoform a [Homo sapi... 59 2e-08
gi|145312270 tudor and KH domain containing isoform a [Homo sapi... 59 2e-08
gi|145312256 tudor and KH domain containing isoform a [Homo sapi... 59 2e-08
gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a ... 58 2e-08
gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b ... 58 2e-08
>gi|56237027 insulin-like growth factor 2 mRNA binding protein 1
isoform 1 [Homo sapiens]
Length = 577
Score = 1136 bits (2938), Expect = 0.0
Identities = 577/577 (100%), Positives = 577/577 (100%)
Query: 1 MNKLYIGNLNESVTPADLEKVFAEHKISYSGQFLVKSGYAFVDCPDEHWAMKAIETFSGK 60
MNKLYIGNLNESVTPADLEKVFAEHKISYSGQFLVKSGYAFVDCPDEHWAMKAIETFSGK
Sbjct: 1 MNKLYIGNLNESVTPADLEKVFAEHKISYSGQFLVKSGYAFVDCPDEHWAMKAIETFSGK 60
Query: 61 VELQGKRLEIEHSVPKKQRSRKIQIRNIPPQLRWEVLDSLLAQYGTVENCEQVNTESETA 120
VELQGKRLEIEHSVPKKQRSRKIQIRNIPPQLRWEVLDSLLAQYGTVENCEQVNTESETA
Sbjct: 61 VELQGKRLEIEHSVPKKQRSRKIQIRNIPPQLRWEVLDSLLAQYGTVENCEQVNTESETA 120
Query: 121 VVNVTYSNREQTRQAIMKLNGHQLENHALKVSYIPDEQIAQGPENGRRGGFGSRGQPRQG 180
VVNVTYSNREQTRQAIMKLNGHQLENHALKVSYIPDEQIAQGPENGRRGGFGSRGQPRQG
Sbjct: 121 VVNVTYSNREQTRQAIMKLNGHQLENHALKVSYIPDEQIAQGPENGRRGGFGSRGQPRQG 180
Query: 181 SPVAAGAPAKQQQVDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAA 240
SPVAAGAPAKQQQVDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAA
Sbjct: 181 SPVAAGAPAKQQQVDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAA 240
Query: 241 EKAISVHSTPEGCSSACKMILEIMHKEAKDTKTADEVPLKILAHNNFVGRLIGKEGRNLK 300
EKAISVHSTPEGCSSACKMILEIMHKEAKDTKTADEVPLKILAHNNFVGRLIGKEGRNLK
Sbjct: 241 EKAISVHSTPEGCSSACKMILEIMHKEAKDTKTADEVPLKILAHNNFVGRLIGKEGRNLK 300
Query: 301 KVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVAAMSL 360
KVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVAAMSL
Sbjct: 301 KVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVAAMSL 360
Query: 361 QSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAI 420
QSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAI
Sbjct: 361 QSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAI 420
Query: 421 IGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEENFF 480
IGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEENFF
Sbjct: 421 IGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEENFF 480
Query: 481 GPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQVIVKII 540
GPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQVIVKII
Sbjct: 481 GPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQVIVKII 540
Query: 541 GHFYASQMAQRKIRDILAQVKQQHQKGQSNQAQARRK 577
GHFYASQMAQRKIRDILAQVKQQHQKGQSNQAQARRK
Sbjct: 541 GHFYASQMAQRKIRDILAQVKQQHQKGQSNQAQARRK 577
>gi|30795212 insulin-like growth factor 2 mRNA binding protein 3
[Homo sapiens]
Length = 579
Score = 843 bits (2179), Expect = 0.0
Identities = 433/585 (74%), Positives = 496/585 (84%), Gaps = 14/585 (2%)
Query: 1 MNKLYIGNLNESVTPADLEKVFAEHKISYSGQFLVKSGYAFVDCPDEHWAMKAIETFSGK 60
MNKLYIGNL+E+ P+DLE +F + KI SG FLVK+GYAFVDCPDE WA+KAIE SGK
Sbjct: 1 MNKLYIGNLSENAAPSDLESIFKDAKIPVSGPFLVKTGYAFVDCPDESWALKAIEALSGK 60
Query: 61 VELQGKRLEIEHSVPKKQRSRKIQIRNIPPQLRWEVLDSLLAQYGTVENCEQVNTESETA 120
+EL GK +E+EHSVPK+QR RK+QIRNIPP L+WEVLDSLL QYG VE+CEQVNT+SETA
Sbjct: 61 IELHGKPIEVEHSVPKRQRIRKLQIRNIPPHLQWEVLDSLLVQYGVVESCEQVNTDSETA 120
Query: 121 VVNVTYSNREQTRQAIMKLNGHQLENHALKVSYIPDEQIA-QGPENGRRG--GFGSRGQP 177
VVNVTYS+++Q RQA+ KLNG QLEN LKV+YIPDE A Q P RG G G RG
Sbjct: 121 VVNVTYSSKDQARQALDKLNGFQLENFTLKVAYIPDEMAAQQNPLQQPRGRRGLGQRGSS 180
Query: 178 RQGSPVAAGAPAKQQQVDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENA 237
RQGSP G+ +KQ+ D+PLRLLVPTQ+VGAIIGKEGATIRNITKQTQSKIDVHRKENA
Sbjct: 181 RQGSP---GSVSKQKPCDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENA 237
Query: 238 GAAEKAISVHSTPEGCSSACKMILEIMHKEAKDTKTADEVPLKILAHNNFVGRLIGKEGR 297
GAAEK+I++ STPEG S+ACK ILEIMHKEA+D K +E+PLKILAHNNFVGRLIGKEGR
Sbjct: 238 GAAEKSITILSTPEGTSAACKSILEIMHKEAQDIKFTEEIPLKILAHNNFVGRLIGKEGR 297
Query: 298 NLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVAA 357
NLKK+EQDT+TKITIS LQ+LTLYNPERTITVKG +E C +AE+EIMKK+RE+YEND+A+
Sbjct: 298 NLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRESYENDIAS 357
Query: 358 MSLQSHLIPGLNLAAVGLFPASSSAVPP---PPSSVTGAAPYSSFMQAPEQEMVQVFIPA 414
M+LQ+HLIPGLNL A+GLFP +S PP PPS++T PY F Q+ E E V +FIPA
Sbjct: 358 MNLQAHLIPGLNLNALGLFPPTSGMPPPTSGPPSAMT--PPYPQFEQS-ETETVHLFIPA 414
Query: 415 QAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIYGKL 474
+VGAIIGK+GQHIKQLSRFA ASIKIAP E PD+KVRMVIITGPPEAQFKAQGRIYGK+
Sbjct: 415 LSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGKI 474
Query: 475 KEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQ 534
KEENF PKEEVKLE HIRVP+ AAGRVIGKGGKTVNELQNL++AEVVVPRDQTPDENDQ
Sbjct: 475 KEENFVSPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQ 534
Query: 535 VIVKIIGHFYASQMAQRKIRDILAQVKQQHQKG--QSNQAQARRK 577
V+VKI GHFYA Q+AQRKI++IL QVKQ Q+ QS Q+RRK
Sbjct: 535 VVVKITGHFYACQVAQRKIQEILTQVKQHQQQKALQSGPPQSRRK 579
>gi|64085377 insulin-like growth factor 2 mRNA binding protein 2
isoform a [Homo sapiens]
Length = 599
Score = 777 bits (2006), Expect = 0.0
Identities = 396/603 (65%), Positives = 476/603 (78%), Gaps = 31/603 (5%)
Query: 1 MNKLYIGNLNESVTPADLEKVFAEHKISYSGQFLVKSGYAFVDCPDEHWAMKAIETFSGK 60
MNKLYIGNL+ +VT DL ++F + K+ +GQ L+KSGYAFVD PD++WA++AIET SGK
Sbjct: 2 MNKLYIGNLSPAVTADDLRQLFGDRKLPLAGQVLLKSGYAFVDYPDQNWAIRAIETLSGK 61
Query: 61 VELQGKRLEIEHSVPKKQRSRKIQIRNIPPQLRWEVLDSLLAQYGTVENCEQVNTESETA 120
VEL GK +E+++SV KK RSRKIQIRNIPP L+WEVLD LLAQYGTVEN EQVNT++ETA
Sbjct: 62 VELHGKIMEVDYSVSKKLRSRKIQIRNIPPHLQWEVLDGLLAQYGTVENVEQVNTDTETA 121
Query: 121 VVNVTYSNREQTRQAIMKLNGHQLENHALKVSYIPDEQIAQG--PENGRRGGFGSRGQPR 178
VVNVTY+ RE+ + A+ KL+GHQ EN++ K+SYIPDE+++ P+ +RG SR Q
Sbjct: 122 VVNVTYATREEAKIAMEKLSGHQFENYSFKISYIPDEEVSSPSPPQRAQRGDHSSREQGH 181
Query: 179 QGSPVAAGAPAKQQQVDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAG 238
A G ++ +Q+D PLR+LVPTQ+VGAIIGKEG TI+NITKQTQS++D+HRKEN+G
Sbjct: 182 -----APGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSG 236
Query: 239 AAEKAISVHSTPEGCSSACKMILEIMHKEAKDTKTADEVPLKILAHNNFVGRLIGKEGRN 298
AAEK +++H+TPEG S AC+MILEIM KEA +TK A+E+PLKILAHN VGRLIGKEGRN
Sbjct: 237 AAEKPVTIHATPEGTSEACRMILEIMQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRN 296
Query: 299 LKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVAAM 358
LKK+E +T TKITISSLQDL++YNPERTITVKG +E C AE EIMKK+REA+END+ A+
Sbjct: 297 LKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAV 356
Query: 359 SLQSHLIPGLNLAAVGLFPASSSAVPPP--PSSVTGAAPYSSFM---------------- 400
+ Q++LIPGLNL+A+G+F S + PP P AAPY F
Sbjct: 357 NQQANLIPGLNLSALGIFSTGLSVLSPPAGPRGAPPAAPYHPFTTHSGYFSSLYPHHQFG 416
Query: 401 ------QAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMV 454
PEQE+V +FIP QAVGAIIGKKG HIKQL+RFA ASIKIAP E PD RMV
Sbjct: 417 PFPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMV 476
Query: 455 IITGPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQ 514
IITGPPEAQFKAQGRI+GKLKEENFF PKEEVKLE HIRVP+S AGRVIGKGGKTVNELQ
Sbjct: 477 IITGPPEAQFKAQGRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQ 536
Query: 515 NLTAAEVVVPRDQTPDENDQVIVKIIGHFYASQMAQRKIRDILAQVKQQHQKGQSNQAQA 574
NLT+AEV+VPRDQTPDEN++VIV+IIGHF+ASQ AQRKIR+I+ QVKQQ QK A
Sbjct: 537 NLTSAEVIVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQKYPQGVASQ 596
Query: 575 RRK 577
R K
Sbjct: 597 RSK 599
>gi|56118219 insulin-like growth factor 2 mRNA binding protein 2
isoform b [Homo sapiens]
Length = 556
Score = 744 bits (1922), Expect = 0.0
Identities = 383/579 (66%), Positives = 458/579 (79%), Gaps = 26/579 (4%)
Query: 1 MNKLYIGNLNESVTPADLEKVFAEHKISYSGQFLVKSGYAFVDCPDEHWAMKAIETFSGK 60
MNKLYIGNL+ +VT DL ++F + K+ +GQ L+KSGYAFVD PD++WA++AIET SGK
Sbjct: 2 MNKLYIGNLSPAVTADDLRQLFGDRKLPLAGQVLLKSGYAFVDYPDQNWAIRAIETLSGK 61
Query: 61 VELQGKRLEIEHSVPKKQRSRKIQIRNIPPQLRWEVLDSLLAQYGTVENCEQVNTESETA 120
VEL GK +E+++SV KK RSRKIQIRNIPP L+WEVLD LLAQYGTVEN EQVNT++ETA
Sbjct: 62 VELHGKIMEVDYSVSKKLRSRKIQIRNIPPHLQWEVLDGLLAQYGTVENVEQVNTDTETA 121
Query: 121 VVNVTYSNREQTRQAIMKLNGHQLENHALKVSYIPDEQIAQG--PENGRRGGFGSRGQPR 178
VVNVTY+ RE+ + A+ KL+GHQ EN++ K+SYIPDE+++ P+ +RG SR Q
Sbjct: 122 VVNVTYATREEAKIAMEKLSGHQFENYSFKISYIPDEEVSSPSPPQRAQRGDHSSREQGH 181
Query: 179 QGSPVAAGAPAKQQQVDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAG 238
A G ++ +Q+D PLR+LVPTQ+VGAIIGKEG TI+NITKQTQS++D+HRKEN+G
Sbjct: 182 -----APGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSG 236
Query: 239 AAEKAISVHSTPEGCSSACKMILEIMHKEAKDTKTADEVPLKILAHNNFVGRLIGKEGRN 298
AAEK +++H+TPEG S AC+MILEIM KEA +TK A+E+PLKILAHN VGRLIGKEGRN
Sbjct: 237 AAEKPVTIHATPEGTSEACRMILEIMQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRN 296
Query: 299 LKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVAAM 358
LKK+E +T TKITISSLQDL++YNPERTITVKG +E C AE EIMKK+REA+END+ A+
Sbjct: 297 LKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAV 356
Query: 359 SLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVG 418
+ S G F SS P P+ PEQE+V +FIP QAVG
Sbjct: 357 NTHS-----------GYF---SSLYPHHQFG-----PFPHHHSYPEQEIVNLFIPTQAVG 397
Query: 419 AIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEEN 478
AIIGKKG HIKQL+RFA ASIKIAP E PD RMVIITGPPEAQFKAQGRI+GKLKEEN
Sbjct: 398 AIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKEEN 457
Query: 479 FFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQVIVK 538
FF PKEEVKLE HIRVP+S AGRVIGKGGKTVNELQNLT+AEV+VPRDQTPDEN++VIV+
Sbjct: 458 FFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIVR 517
Query: 539 IIGHFYASQMAQRKIRDILAQVKQQHQKGQSNQAQARRK 577
IIGHF+ASQ AQRKIR+I+ QVKQQ QK A R K
Sbjct: 518 IIGHFFASQTAQRKIREIVQQVKQQEQKYPQGVASQRSK 556
>gi|238624257 insulin-like growth factor 2 mRNA binding protein 1
isoform 2 [Homo sapiens]
Length = 438
Score = 601 bits (1550), Expect = e-172
Identities = 314/360 (87%), Positives = 325/360 (90%), Gaps = 6/360 (1%)
Query: 218 IRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGCSSACKMILEIMHKEAKDTKTADEV 277
IRNI Q + ++ G E V++ E ++ + + + T+ ADEV
Sbjct: 85 IRNIPPQLRWEVLDSLLAQYGTVENCEQVNTESETA------VVNVTYSNREQTRQADEV 138
Query: 278 PLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCC 337
PLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCC
Sbjct: 139 PLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCC 198
Query: 338 RAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYS 397
RAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYS
Sbjct: 199 RAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYS 258
Query: 398 SFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIIT 457
SFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIIT
Sbjct: 259 SFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIIT 318
Query: 458 GPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLT 517
GPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLT
Sbjct: 319 GPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLT 378
Query: 518 AAEVVVPRDQTPDENDQVIVKIIGHFYASQMAQRKIRDILAQVKQQHQKGQSNQAQARRK 577
AAEVVVPRDQTPDENDQVIVKIIGHFYASQMAQRKIRDILAQVKQQHQKGQSNQAQARRK
Sbjct: 379 AAEVVVPRDQTPDENDQVIVKIIGHFYASQMAQRKIRDILAQVKQQHQKGQSNQAQARRK 438
Score = 290 bits (741), Expect = 3e-78
Identities = 200/498 (40%), Positives = 263/498 (52%), Gaps = 112/498 (22%)
Query: 1 MNKLYIGNLNESVTPADLEKVFAEHKISYSGQFLVKSGYAFVDCPDEHWAMKAIETFSGK 60
MNKLYIGNLNESVTPADLEKVFAEHKISYSGQFLVKSGYAFVDCPDEHWAMKAIETFSGK
Sbjct: 1 MNKLYIGNLNESVTPADLEKVFAEHKISYSGQFLVKSGYAFVDCPDEHWAMKAIETFSGK 60
Query: 61 VELQGKRLEIEHSVPKKQRSRKIQIRNIPPQLRWEVLDSLLAQYGTVENCEQVNTESETA 120
VELQGKRLEIEHSVPKKQRSRKIQIRNIPPQLRWEVLDSLLAQYGTVENCEQVNTESETA
Sbjct: 61 VELQGKRLEIEHSVPKKQRSRKIQIRNIPPQLRWEVLDSLLAQYGTVENCEQVNTESETA 120
Query: 121 VVNVTYSNREQTRQAIMKLNGHQLENHALKVSYIPDEQIAQGPENGRRGGFGSRGQPRQG 180
VVNVTYS +R Q RQ
Sbjct: 121 VVNVTYS---------------------------------------------NREQTRQA 135
Query: 181 SPVAAGAPAKQQQVDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGA- 239
++PL++L +VG +IGKEG ++ + + T++KI + ++
Sbjct: 136 D-------------EVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLY 182
Query: 240 -AEKAISVHSTPEGCSSACKMILEIMHKEAKDTKTADEVPLKILAHNNFVGRLIGKEGRN 298
E+ I+V E C C+ EIM K+ ++ D + + +H LI G N
Sbjct: 183 NPERTITVKGAIENC---CRAEQEIM-KKVREAYENDVAAMSLQSH------LI--PGLN 230
Query: 299 LKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVAAM 358
L V + + P ++T + +A ++ M +V + A +
Sbjct: 231 LAAVGLFPASSSAVPP--------PPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAII 282
Query: 359 SLQSHLIPGLNLAAVGLFPASSSAVPPP--PSS------VTGAAPYSSFMQ--------- 401
+ G ++ + F ++S + PP P S +TG P + F
Sbjct: 283 GKK-----GQHIKQLSRFASASIKIAPPETPDSKVRMVIITG-PPEAQFKAQGRIYGKLK 336
Query: 402 -----APEQEM---VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRM 453
P++E+ + +PA A G +IGK G+ + +L +A + + +TPD ++
Sbjct: 337 EENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQV 396
Query: 454 VI-ITGPPEAQFKAQGRI 470
++ I G A AQ +I
Sbjct: 397 IVKIIGHFYASQMAQRKI 414
>gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens]
Length = 345
Score = 83.2 bits (204), Expect = 6e-16
Identities = 73/320 (22%), Positives = 141/320 (44%), Gaps = 25/320 (7%)
Query: 176 QPRQGSPVAAGAPAKQQQVDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKE 235
QP+ G + + V + +RLL+ + VG+IIGK+G T++ + +++ ++I++
Sbjct: 26 QPQFGRRMESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINI---S 82
Query: 236 NAGAAEKAISVHSTPEGCSSACKMIL-----EIMHKEAKDTKTA-DEVPLKILAHNNFVG 289
E+ +++ + A MI +I++ + T+ V L+++ + G
Sbjct: 83 EGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCG 142
Query: 290 RLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVRE 349
LIGK G +K++ + T ++ ++ D+ + ER +T+ G + + ++I + E
Sbjct: 143 SLIGKGGSKIKEIRESTGAQVQVAG--DMLPNSTERAVTISGTPDAIIQCVKQICVVMLE 200
Query: 350 AYE------------NDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYS 397
AY + +++Q P L FP + + S
Sbjct: 201 AYTIQGQYAIPHPDLTKLHQLAMQQTPFPPLGQTNPA-FPGEKLPLHSSEEAQNLMGQSS 259
Query: 398 SFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIIT 457
+P ++ IP +G IIG++G I ++ + + A IKIA T S R + IT
Sbjct: 260 GLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIA-NATEGSSERQITIT 318
Query: 458 GPPEAQFKAQGRIYGKLKEE 477
G P AQ I +L E
Sbjct: 319 GTPANISLAQYLINARLTSE 338
Score = 72.4 bits (176), Expect = 1e-12
Identities = 43/134 (32%), Positives = 72/134 (53%), Gaps = 8/134 (5%)
Query: 408 VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQ 467
+++ + + VG+IIGKKG+ +K++ + A I I+ P+ R+V ITGP +A FKA
Sbjct: 48 IRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPE---RIVTITGPTDAIFKAF 104
Query: 468 GRIYGKLKEENFFGPKE-----EVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVV 522
I K +E+ + + + VPAS G +IGKGG + E++ T A+V
Sbjct: 105 AMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQ 164
Query: 523 VPRDQTPDENDQVI 536
V D P+ ++ +
Sbjct: 165 VAGDMLPNSTERAV 178
>gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens]
Length = 318
Score = 77.4 bits (189), Expect = 3e-14
Identities = 72/309 (23%), Positives = 137/309 (44%), Gaps = 34/309 (11%)
Query: 194 VDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGC 253
V + +RLL+ + VG+IIGK+G +++ + +++ ++I++ E+ I++
Sbjct: 12 VTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI---SEGNCPERIITLAGPTNAI 68
Query: 254 SSACKMILEIMHKEAKDTKTADE------VPLKILAHNNFVGRLIGKEGRNLKKVEQDTE 307
A MI++ + ++ + T V L+++ + G LIGK G +K++ + T
Sbjct: 69 FKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTG 128
Query: 308 TKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVA----------- 356
++ ++ D+ + ER IT+ G ++ ++I + E+ V
Sbjct: 129 AQVQVAG--DMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSP 186
Query: 357 -------AMSLQS-HLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSSFMQAPEQEMV 408
A ++Q + IP +L + S P + +A + Q E+
Sbjct: 187 VIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSAGLDASAQTTSHELT 246
Query: 409 QVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQG 468
IP +G IIG++G I ++ + + A IKIA P S R V ITG + AQ
Sbjct: 247 ---IPNDLIGCIIGRQGAKINEIRQMSGAQIKIANP-VEGSTDRQVTITGSAASISLAQY 302
Query: 469 RIYGKLKEE 477
I +L E
Sbjct: 303 LINVRLSSE 311
Score = 70.5 bits (171), Expect = 4e-12
Identities = 42/134 (31%), Positives = 70/134 (52%), Gaps = 8/134 (5%)
Query: 408 VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQ 467
+++ + + VG+IIGKKG+ +K++ + A I I+ P+ R++ + GP A FKA
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPE---RIITLAGPTNAIFKAF 72
Query: 468 GRIYGKLKEENFFGPKEEVK-----LETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVV 522
I KL+E+ + + VPAS G +IGKGG + E++ T A+V
Sbjct: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQ 132
Query: 523 VPRDQTPDENDQVI 536
V D P+ ++ I
Sbjct: 133 VAGDMLPNSTERAI 146
>gi|100816392 far upstream element (FUSE) binding protein 3 [Homo
sapiens]
Length = 572
Score = 75.1 bits (183), Expect = 2e-13
Identities = 94/423 (22%), Positives = 167/423 (39%), Gaps = 79/423 (18%)
Query: 142 HQLENHALKVSYIPDEQIAQGPENGRRGGFGSRGQPRQ-GSPVAAGAPAKQQQVDIPLRL 200
H++ A K+ IP + + G+G + +P G GA Q+ V I
Sbjct: 24 HRVRQIAAKIDSIPHLNNSTPLVDPSVYGYGVQKRPLDDGVGNQLGALVHQRTV-ITEEF 82
Query: 201 LVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGCSSACKMI 260
VP + VG IIG+ G I I ++ KI + E++G E+ + TPE A +++
Sbjct: 83 KVPDKMVGFIIGRGGEQISRIQAESGCKIQI-ASESSGIPERPCVLTGTPESIEQAKRLL 141
Query: 261 LEIM---------HKEAKDTKTADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKIT 311
+I+ H + T E IL + VG +IG+ G +K++++ T K+
Sbjct: 142 GQIVDRCRNGPGFHNDIDSNSTIQE----ILIPASKVGLVIGRGGETIKQLQERTGVKMV 197
Query: 312 ISSLQDLTL-YNPERTITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNL 370
+ +QD L ++ + + G +A + +++ +RE + D +
Sbjct: 198 M--IQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVR----------- 244
Query: 371 AAVGLFPASSSAVPPPPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQ 430
F ++V +P AVG +IG+ G+ IK+
Sbjct: 245 --------------------------GDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKK 278
Query: 431 LSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIYGKL----KEENFFGPKEEV 486
+ A I+ P + S R + GPP+ + + I +L +E + FG
Sbjct: 279 IQNDAGVRIQFKPDDGI-SPERAAQVMGPPD-RCQHAAHIISELILTAQERDGFGGLAAA 336
Query: 487 K-----------------LETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTP 529
+ E VPA G VIGKGG+ + + + A V + R+ P
Sbjct: 337 RGRGRGRGDWSVGAPGGVQEITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPP 396
Query: 530 DEN 532
+ +
Sbjct: 397 NSD 399
Score = 67.4 bits (163), Expect = 3e-11
Identities = 46/169 (27%), Positives = 87/169 (51%), Gaps = 7/169 (4%)
Query: 412 IPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIY 471
+P + VG IIG+ G+ I ++ + I+IA E+ R ++TG PE+ +A+ R+
Sbjct: 84 VPDKMVGFIIGRGGEQISRIQAESGCKIQIAS-ESSGIPERPCVLTGTPESIEQAK-RLL 141
Query: 472 GKLKEENFFGPKEEVKLETH-----IRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRD 526
G++ + GP ++++ I +PAS G VIG+GG+T+ +LQ T ++V+ +D
Sbjct: 142 GQIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQD 201
Query: 527 QTPDENDQVIVKIIGHFYASQMAQRKIRDILAQVKQQHQKGQSNQAQAR 575
++I G + Q A+ + +I+ + Q +G +R
Sbjct: 202 GPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVRGDFNSR 250
Score = 63.9 bits (154), Expect = 4e-10
Identities = 69/295 (23%), Positives = 117/295 (39%), Gaps = 40/295 (13%)
Query: 200 LLVPTQYVGAIIGKEGATIRNITKQTQSK-IDVHRKENAGAAEKAISVHSTPEGCSSACK 258
+L+P VG +IG+ G TI+ + ++T K + + A+K + + A +
Sbjct: 167 ILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQARE 226
Query: 259 MILEIM-HKEAKD--------TKTADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETK 309
M+LEI+ K+ D +++ VG +IG+ G +KK++ D +
Sbjct: 227 MVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVR 286
Query: 310 ITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLN 369
I + +PER V G + C A I + + A E D
Sbjct: 287 IQFKPDDGI---SPERAAQVMGPPDRCQHAAHIISELILTAQERD--------------- 328
Query: 370 LAAVGLFPASSSAVPPPPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIK 429
GL A G +S QE+ +PA G +IGK G++IK
Sbjct: 329 -GFGGLAAARGRG--------RGRGDWSVGAPGGVQEITYT-VPADKCGLVIGKGGENIK 378
Query: 430 QLSRFASASIKIA--PPETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEENFFGP 482
+++ + A +++ PP D +R I G P+ A+ I K+ N P
Sbjct: 379 SINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVARQLIDEKVGGTNLGAP 433
Score = 43.5 bits (101), Expect = 5e-04
Identities = 57/268 (21%), Positives = 103/268 (38%), Gaps = 65/268 (24%)
Query: 285 NNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKG---AIENCCRAEQ 341
+ VG +IG+ G + +++ ++ KI I+S PER + G +IE R
Sbjct: 86 DKMVGFIIGRGGEQISRIQAESGCKIQIASESSGI---PERPCVLTGTPESIEQAKRLLG 142
Query: 342 EIMKKVREA--YENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSSF 399
+I+ + R + ND+ + S
Sbjct: 143 QIVDRCRNGPGFHNDIDSNST--------------------------------------- 163
Query: 400 MQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQL-SRFASASIKIAPPETPDSKVRMVIITG 458
+ ++ IPA VG +IG+ G+ IKQL R + I P + + ITG
Sbjct: 164 -------IQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITG 216
Query: 459 PPEAQFKAQGRIYGKLKEE---NFFGPKEEVKL-----ETHIRVPASAAGRVIGKGGKTV 510
+A+ + ++E+ +F G + + + VP A G VIG+ G+ +
Sbjct: 217 DAFKVQQAREMVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMI 276
Query: 511 NELQNLTAAEVVVPRDQ--TPDENDQVI 536
++QN + D +P+ QV+
Sbjct: 277 KKIQNDAGVRIQFKPDDGISPERAAQVM 304
Score = 42.4 bits (98), Expect = 0.001
Identities = 53/225 (23%), Positives = 82/225 (36%), Gaps = 46/225 (20%)
Query: 198 LRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAA-EKAISVHSTPEGCSSA 256
+ + VP VG +IG+ G I+ I Q + + + K + G + E+A V P+ C A
Sbjct: 256 IEVSVPRFAVGIVIGRNGEMIKKI--QNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHA 313
Query: 257 CKMILE-IMHKEAKD----------------------TKTADEVPLKILAHNNFVGRLIG 293
+I E I+ + +D E+ + A G +IG
Sbjct: 314 AHIISELILTAQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYTVPADK--CGLVIG 371
Query: 294 KEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYEN 353
K G N+K + Q + + + R T++G + A Q I +KV
Sbjct: 372 KGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVARQLIDEKVG----- 426
Query: 354 DVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSS 398
G NL A G F S + PP P P SS
Sbjct: 427 -------------GTNLGAPGAFGQSPFSQPPAPPHQNTFPPRSS 458
Score = 37.7 bits (86), Expect = 0.029
Identities = 27/101 (26%), Positives = 48/101 (47%), Gaps = 10/101 (9%)
Query: 168 RGGFG----SRGQPRQGSPVAAGAPAKQQQVDIPLRLLVPTQYVGAIIGKEGATIRNITK 223
R GFG +RG+ R + GAP Q++ VP G +IGK G I++I +
Sbjct: 327 RDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYT----VPADKCGLVIGKGGENIKSINQ 382
Query: 224 QTQSKIDVHRK--ENAGAAEKAISVHSTPEGCSSACKMILE 262
Q+ + +++ R N+ + ++ P+ A ++I E
Sbjct: 383 QSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVARQLIDE 423
>gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens]
Length = 371
Score = 73.9 bits (180), Expect = 4e-13
Identities = 82/345 (23%), Positives = 146/345 (42%), Gaps = 49/345 (14%)
Query: 176 QPRQGSPVAAGAPAKQQQVDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKE 235
QP+ G + + V + +RLL+ + VG+IIGK+G T++ + +++ ++I++
Sbjct: 26 QPQFGRRMESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINI---S 82
Query: 236 NAGAAEKAISVHSTPEGCSSACKMIL-----EIMHKEAKDTKTA-DEVPLKILAHNNFVG 289
E+ +++ + A MI +I++ + T+ V L+++ + G
Sbjct: 83 EGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCG 142
Query: 290 RLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKG---AIENCCRAEQEIM-- 344
LIGK G +K++ + T ++ ++ D+ + ER +T+ G AI C + +M
Sbjct: 143 SLIGKGGSKIKEIRESTGAQVQVAG--DMLPNSTERAVTISGTPDAIIQCVKQICVVMLE 200
Query: 345 ---KKVREAYENDVAAMSL-----QSHLIPGLNL-----AAVGLFPASSSAVPPPPSSVT 391
K Y A+ + Q++ I G L + P PP T
Sbjct: 201 SPPKGATIPYRPKPASTPVIFAGGQAYTIQGQYAIPHPDQLTKLHQLAMQQTPFPPLGQT 260
Query: 392 GAA------PYSSFMQA-------------PEQEMVQVFIPAQAVGAIIGKKGQHIKQLS 432
A P S +A P ++ IP +G IIG++G I ++
Sbjct: 261 NPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIR 320
Query: 433 RFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEE 477
+ + A IKIA T S R + ITG P AQ I +L E
Sbjct: 321 QMSGAQIKIA-NATEGSSERQITITGTPANISLAQYLINARLTSE 364
Score = 72.4 bits (176), Expect = 1e-12
Identities = 43/134 (32%), Positives = 72/134 (53%), Gaps = 8/134 (5%)
Query: 408 VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQ 467
+++ + + VG+IIGKKG+ +K++ + A I I+ P+ R+V ITGP +A FKA
Sbjct: 48 IRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPE---RIVTITGPTDAIFKAF 104
Query: 468 GRIYGKLKEENFFGPKE-----EVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVV 522
I K +E+ + + + VPAS G +IGKGG + E++ T A+V
Sbjct: 105 AMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQ 164
Query: 523 VPRDQTPDENDQVI 536
V D P+ ++ +
Sbjct: 165 VAGDMLPNSTERAV 178
>gi|222352151 poly(rC) binding protein 1 [Homo sapiens]
Length = 356
Score = 73.2 bits (178), Expect = 6e-13
Identities = 81/358 (22%), Positives = 143/358 (39%), Gaps = 67/358 (18%)
Query: 185 AGAPAKQQQVDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAI 244
AG V + +RLL+ + VG+IIGK+G +++ I +++ ++I++ E+ I
Sbjct: 3 AGVTESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINI---SEGNCPERII 59
Query: 245 SVHSTPEGCSSACKMILEIMHKEAKDTKT------ADEVPLKILAHNNFVGRLIGKEGRN 298
++ A MI++ + ++ + T V L+++ G LIGK G
Sbjct: 60 TLTGPTNAIFKAFAMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCK 119
Query: 299 LKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYE------ 352
+K++ + T ++ ++ D+ + ER IT+ G ++ ++I + E
Sbjct: 120 IKEIRESTGAQVQVAG--DMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGR 177
Query: 353 ------------------------NDVA---------------AMSLQ-SHLIPGLNLAA 372
+D A A S+Q H I L+LA
Sbjct: 178 VMTIPYQPMPASSPVICAGGQDRCSDAAGYPHATHDLEGPPLDAYSIQGQHTISPLDLAK 237
Query: 373 VGLFPASSS---------AVPPPPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGK 423
+ S SS Y + + A Q ++ IP +G IIG+
Sbjct: 238 LNQVARQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDASTQTTHELTIPNNLIGCIIGR 297
Query: 424 KGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEENFFG 481
+G +I ++ + + A IKIA P S R V ITG + AQ I +L E G
Sbjct: 298 QGANINEIRQMSGAQIKIANP-VEGSSGRQVTITGSAASISLAQYLINARLSSEKGMG 354
Score = 71.2 bits (173), Expect = 2e-12
Identities = 44/136 (32%), Positives = 74/136 (54%), Gaps = 12/136 (8%)
Query: 408 VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQ 467
+++ + + VG+IIGKKG+ +K++ + A I I+ P+ R++ +TGP A FKA
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCPE---RIITLTGPTNAIFKAF 72
Query: 468 GRIYGKLKEE-------NFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAE 520
I KL+E+ + + V L + VPA+ G +IGKGG + E++ T A+
Sbjct: 73 AMIIDKLEEDINSSMTNSTAASRPPVTLR--LVVPATQCGSLIGKGGCKIKEIRESTGAQ 130
Query: 521 VVVPRDQTPDENDQVI 536
V V D P+ ++ I
Sbjct: 131 VQVAGDMLPNSTERAI 146
Score = 60.5 bits (145), Expect = 4e-09
Identities = 54/230 (23%), Positives = 99/230 (43%), Gaps = 47/230 (20%)
Query: 279 LKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCR 338
+++L H VG +IGK+G ++K++ +++ +I IS PER IT+ G +
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNC-----PERIITLTGPTNAIFK 70
Query: 339 AEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSS 398
A I+ K+ E + + +S+A PP ++
Sbjct: 71 AFAMIIDKLEEDINSSMT----------------------NSTAASRPPVTL-------- 100
Query: 399 FMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITG 458
++ +PA G++IGK G IK++ A +++A P+S R + I G
Sbjct: 101 ----------RLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAG 150
Query: 459 PPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGK 508
P++ + +I + E P+ V + +PAS+ VI GG+
Sbjct: 151 VPQSVTECVKQICLVMLETLSQSPQGRVMTIPYQPMPASSP--VICAGGQ 198
Score = 29.6 bits (65), Expect = 7.9
Identities = 16/63 (25%), Positives = 26/63 (41%)
Query: 169 GGFGSRGQPRQGSPVAAGAPAKQQQVDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSK 228
GG G G V + L +P +G IIG++GA I I + + ++
Sbjct: 253 GGTGFAGIDSSSPEVKGYWASLDASTQTTHELTIPNNLIGCIIGRQGANINEIRQMSGAQ 312
Query: 229 IDV 231
I +
Sbjct: 313 IKI 315
>gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens]
Length = 331
Score = 72.4 bits (176), Expect = 1e-12
Identities = 74/319 (23%), Positives = 142/319 (44%), Gaps = 41/319 (12%)
Query: 194 VDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGC 253
V + +RLL+ + VG+IIGK+G +++ + +++ ++I++ E+ I++
Sbjct: 12 VTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI---SEGNCPERIITLAGPTNAI 68
Query: 254 SSACKMILEIMHKEAKDTKT------ADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTE 307
A MI++ + ++ + T V L+++ + G LIGK G +K++ + T
Sbjct: 69 FKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTG 128
Query: 308 TKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVA----------- 356
++ ++ D+ + ER IT+ G ++ ++I + E+ V
Sbjct: 129 AQVQVAG--DMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSP 186
Query: 357 -------AMSLQ-SHLIPGLNLAAVGLFPASSSAVPPPP-----SSVTGAAP----YSSF 399
A ++Q + IP +L + S P S + ++P Y +
Sbjct: 187 VIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAG 246
Query: 400 MQAPEQEMV-QVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITG 458
+ A Q ++ IP +G IIG++G I ++ + + A IKIA P S R V ITG
Sbjct: 247 LDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANP-VEGSTDRQVTITG 305
Query: 459 PPEAQFKAQGRIYGKLKEE 477
+ AQ I +L E
Sbjct: 306 SAASISLAQYLINVRLSSE 324
Score = 70.5 bits (171), Expect = 4e-12
Identities = 42/134 (31%), Positives = 70/134 (52%), Gaps = 8/134 (5%)
Query: 408 VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQ 467
+++ + + VG+IIGKKG+ +K++ + A I I+ P+ R++ + GP A FKA
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPE---RIITLAGPTNAIFKAF 72
Query: 468 GRIYGKLKEENFFGPKEEVK-----LETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVV 522
I KL+E+ + + VPAS G +IGKGG + E++ T A+V
Sbjct: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQ 132
Query: 523 VPRDQTPDENDQVI 536
V D P+ ++ I
Sbjct: 133 VAGDMLPNSTERAI 146
Score = 30.4 bits (67), Expect = 4.6
Identities = 29/130 (22%), Positives = 55/130 (42%), Gaps = 10/130 (7%)
Query: 131 QTRQAIMKLNGHQLENHALKVSYIPDEQIAQGPENGRRGGFGSRGQPRQGSPVAAGAPAK 190
Q + AI + + +L A++ S+ P +G G G + AG A
Sbjct: 198 QGQYAIPQPDLTKLHQLAMQQSHFP-------MTHGNTGFSGIESSSPEVKGYWAGLDAS 250
Query: 191 QQQVDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTP 250
Q L +P +G IIG++GA I I + + ++I + G+ ++ +++ +
Sbjct: 251 AQTTSH--ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE-GSTDRQVTITGSA 307
Query: 251 EGCSSACKMI 260
S A +I
Sbjct: 308 ASISLAQYLI 317
>gi|14670373 poly(rC) binding protein 4 isoform c [Homo sapiens]
Length = 403
Score = 71.6 bits (174), Expect = 2e-12
Identities = 73/299 (24%), Positives = 134/299 (44%), Gaps = 37/299 (12%)
Query: 194 VDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGC 253
+ + LR+L+ + VG+IIGK+G T++ I +Q+ ++I + E+ ++ +
Sbjct: 16 ITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITI---SEGSCPERITTITGSTAAV 72
Query: 254 SSACKMILEIMHKEA------KDTKTADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTE 307
A MI + ++ + V L+++ + G LIGK G +K++ + T
Sbjct: 73 FHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRETTG 132
Query: 308 TKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVA-----AMSLQS 362
++ ++ DL + ER +TV G + ++I + E+ ++SL +
Sbjct: 133 AQVQVAG--DLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATIPYHPSLSLGT 190
Query: 363 HLI-PGLNLAAVGLFPA------------SSSAVP-PPPSSVTGAAPYSSFMQAPEQEMV 408
L+ + G + A SS AVP PS V G P + Q QE +
Sbjct: 191 VLLSANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPFATPSVVPGLDPGT---QTSSQEFL 247
Query: 409 QVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQ 467
+P +G +IG++G I ++ + + A IKI + + R V ITG P + AQ
Sbjct: 248 ---VPNDLIGCVIGRQGSKISEIRQMSGAHIKIG-NQAEGAGERHVTITGSPVSIALAQ 302
Score = 65.1 bits (157), Expect = 2e-10
Identities = 41/134 (30%), Positives = 68/134 (50%), Gaps = 8/134 (5%)
Query: 408 VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQ 467
+++ + + VG+IIGKKG+ +K++ +SA I I+ P+ R+ ITG A F A
Sbjct: 20 LRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPE---RITTITGSTAAVFHAV 76
Query: 468 GRIYGKLKEENFFGPKE-----EVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVV 522
I KL E+ P + + +PAS G +IGK G + E++ T A+V
Sbjct: 77 SMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQ 136
Query: 523 VPRDQTPDENDQVI 536
V D P+ ++ +
Sbjct: 137 VAGDLLPNSTERAV 150
Score = 42.0 bits (97), Expect = 0.002
Identities = 28/89 (31%), Positives = 43/89 (48%), Gaps = 7/89 (7%)
Query: 187 APAKQQQVDIP---LRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKA 243
APA V P LRL++P G++IGK G I+ I + T +++ V + E+A
Sbjct: 90 APANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERA 149
Query: 244 ISVHSTPEG----CSSACKMILEIMHKEA 268
++V P+ C +ILE K A
Sbjct: 150 VTVSGVPDAIILCVRQICAVILESPPKGA 178
Score = 32.7 bits (73), Expect = 0.93
Identities = 20/86 (23%), Positives = 38/86 (44%), Gaps = 4/86 (4%)
Query: 472 GKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDE 531
G L+EE P+ + L + + G +IGK G+TV ++ ++A + + P+
Sbjct: 6 GGLEEE----PELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPER 61
Query: 532 NDQVIVKIIGHFYASQMAQRKIRDIL 557
+ F+A M K+ + L
Sbjct: 62 ITTITGSTAAVFHAVSMIAFKLDEDL 87
>gi|14670369 poly(rC) binding protein 4 isoform c [Homo sapiens]
Length = 403
Score = 71.6 bits (174), Expect = 2e-12
Identities = 73/299 (24%), Positives = 134/299 (44%), Gaps = 37/299 (12%)
Query: 194 VDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGC 253
+ + LR+L+ + VG+IIGK+G T++ I +Q+ ++I + E+ ++ +
Sbjct: 16 ITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITI---SEGSCPERITTITGSTAAV 72
Query: 254 SSACKMILEIMHKEA------KDTKTADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTE 307
A MI + ++ + V L+++ + G LIGK G +K++ + T
Sbjct: 73 FHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRETTG 132
Query: 308 TKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVA-----AMSLQS 362
++ ++ DL + ER +TV G + ++I + E+ ++SL +
Sbjct: 133 AQVQVAG--DLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATIPYHPSLSLGT 190
Query: 363 HLI-PGLNLAAVGLFPA------------SSSAVP-PPPSSVTGAAPYSSFMQAPEQEMV 408
L+ + G + A SS AVP PS V G P + Q QE +
Sbjct: 191 VLLSANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPFATPSVVPGLDPGT---QTSSQEFL 247
Query: 409 QVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQ 467
+P +G +IG++G I ++ + + A IKI + + R V ITG P + AQ
Sbjct: 248 ---VPNDLIGCVIGRQGSKISEIRQMSGAHIKIG-NQAEGAGERHVTITGSPVSIALAQ 302
Score = 65.1 bits (157), Expect = 2e-10
Identities = 41/134 (30%), Positives = 68/134 (50%), Gaps = 8/134 (5%)
Query: 408 VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQ 467
+++ + + VG+IIGKKG+ +K++ +SA I I+ P+ R+ ITG A F A
Sbjct: 20 LRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPE---RITTITGSTAAVFHAV 76
Query: 468 GRIYGKLKEENFFGPKE-----EVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVV 522
I KL E+ P + + +PAS G +IGK G + E++ T A+V
Sbjct: 77 SMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQ 136
Query: 523 VPRDQTPDENDQVI 536
V D P+ ++ +
Sbjct: 137 VAGDLLPNSTERAV 150
Score = 42.0 bits (97), Expect = 0.002
Identities = 28/89 (31%), Positives = 43/89 (48%), Gaps = 7/89 (7%)
Query: 187 APAKQQQVDIP---LRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKA 243
APA V P LRL++P G++IGK G I+ I + T +++ V + E+A
Sbjct: 90 APANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERA 149
Query: 244 ISVHSTPEG----CSSACKMILEIMHKEA 268
++V P+ C +ILE K A
Sbjct: 150 VTVSGVPDAIILCVRQICAVILESPPKGA 178
Score = 32.7 bits (73), Expect = 0.93
Identities = 20/86 (23%), Positives = 38/86 (44%), Gaps = 4/86 (4%)
Query: 472 GKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDE 531
G L+EE P+ + L + + G +IGK G+TV ++ ++A + + P+
Sbjct: 6 GGLEEE----PELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPER 61
Query: 532 NDQVIVKIIGHFYASQMAQRKIRDIL 557
+ F+A M K+ + L
Sbjct: 62 ITTITGSTAAVFHAVSMIAFKLDEDL 87
>gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens]
Length = 335
Score = 70.5 bits (171), Expect = 4e-12
Identities = 42/134 (31%), Positives = 70/134 (52%), Gaps = 8/134 (5%)
Query: 408 VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQ 467
+++ + + VG+IIGKKG+ +K++ + A I I+ P+ R++ + GP A FKA
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPE---RIITLAGPTNAIFKAF 72
Query: 468 GRIYGKLKEENFFGPKEEVK-----LETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVV 522
I KL+E+ + + VPAS G +IGKGG + E++ T A+V
Sbjct: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQ 132
Query: 523 VPRDQTPDENDQVI 536
V D P+ ++ I
Sbjct: 133 VAGDMLPNSTERAI 146
Score = 69.3 bits (168), Expect = 9e-12
Identities = 73/323 (22%), Positives = 140/323 (43%), Gaps = 45/323 (13%)
Query: 194 VDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGC 253
V + +RLL+ + VG+IIGK+G +++ + +++ ++I++ E+ I++
Sbjct: 12 VTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI---SEGNCPERIITLAGPTNAI 68
Query: 254 SSACKMILEIMHKEAKDTKT------ADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTE 307
A MI++ + ++ + T V L+++ + G LIGK G +K++ + T
Sbjct: 69 FKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTG 128
Query: 308 TKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDV------------ 355
++ ++ D+ + ER IT+ G ++ ++I + E
Sbjct: 129 AQVQVAG--DMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTIPYRPKP 186
Query: 356 ----------AAMSLQ-SHLIPGLNLAAVGLFPASSSAVPPPP-----SSVTGAAP---- 395
A ++Q + IP +L + S P S + ++P
Sbjct: 187 SSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKG 246
Query: 396 YSSFMQAPEQEMV-QVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMV 454
Y + + A Q ++ IP +G IIG++G I ++ + + A IKIA P S R V
Sbjct: 247 YWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANP-VEGSTDRQV 305
Query: 455 IITGPPEAQFKAQGRIYGKLKEE 477
ITG + AQ I +L E
Sbjct: 306 TITGSAASISLAQYLINVRLSSE 328
Score = 59.3 bits (142), Expect = 9e-09
Identities = 53/230 (23%), Positives = 97/230 (42%), Gaps = 48/230 (20%)
Query: 279 LKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCR 338
+++L H VG +IGK+G ++KK+ +++ +I IS PER IT+ G +
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNC-----PERIITLAGPTNAIFK 70
Query: 339 AEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSS 398
A I+ K+ E + + +S+A PP ++
Sbjct: 71 AFAMIIDKLEEDISSSMT----------------------NSTAASRPPVTL-------- 100
Query: 399 FMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITG 458
++ +PA G++IGK G IK++ A +++A P+S R + I G
Sbjct: 101 ----------RLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAG 150
Query: 459 PPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGK 508
P++ + +I + E P + V + P ++ VI GG+
Sbjct: 151 IPQSIIECVKQICVVMLETLSQSPPKGVTIPYR---PKPSSSPVIFAGGQ 197
Score = 30.4 bits (67), Expect = 4.6
Identities = 29/130 (22%), Positives = 55/130 (42%), Gaps = 10/130 (7%)
Query: 131 QTRQAIMKLNGHQLENHALKVSYIPDEQIAQGPENGRRGGFGSRGQPRQGSPVAAGAPAK 190
Q + AI + + +L A++ S+ P +G G G + AG A
Sbjct: 202 QGQYAIPQPDLTKLHQLAMQQSHFP-------MTHGNTGFSGIESSSPEVKGYWAGLDAS 254
Query: 191 QQQVDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTP 250
Q L +P +G IIG++GA I I + + ++I + G+ ++ +++ +
Sbjct: 255 AQTTSH--ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE-GSTDRQVTITGSA 311
Query: 251 EGCSSACKMI 260
S A +I
Sbjct: 312 ASISLAQYLI 321
>gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens]
Length = 361
Score = 70.5 bits (171), Expect = 4e-12
Identities = 42/134 (31%), Positives = 70/134 (52%), Gaps = 8/134 (5%)
Query: 408 VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQ 467
+++ + + VG+IIGKKG+ +K++ + A I I+ P+ R++ + GP A FKA
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPE---RIITLAGPTNAIFKAF 72
Query: 468 GRIYGKLKEENFFGPKEEVK-----LETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVV 522
I KL+E+ + + VPAS G +IGKGG + E++ T A+V
Sbjct: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQ 132
Query: 523 VPRDQTPDENDQVI 536
V D P+ ++ I
Sbjct: 133 VAGDMLPNSTERAI 146
Score = 56.2 bits (134), Expect = 8e-08
Identities = 73/384 (19%), Positives = 150/384 (39%), Gaps = 102/384 (26%)
Query: 194 VDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGC 253
V + +RLL+ + VG+IIGK+G +++ + +++ ++I++ E+ I++
Sbjct: 12 VTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI---SEGNCPERIITLAGPTNAI 68
Query: 254 SSACKMILEIMHKEAKDTKT------ADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTE 307
A MI++ + ++ + T V L+++ + G LIGK G +K++ + T
Sbjct: 69 FKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTG 128
Query: 308 TKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPG 367
++ ++ D+ + ER IT+ G Q I++ V++ + + L+S
Sbjct: 129 AQVQVAG--DMLPNSTERAITIAG-------IPQSIIECVKQ-----ICVVMLES----- 169
Query: 368 LNLAAVGLFPASSSAVPPPPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQH 427
PP VT PY P + +I GQ
Sbjct: 170 ------------------PPKGVT--IPYR---------------PKPSSSPVIFAGGQ- 193
Query: 428 IKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRI------YGKLKE----- 476
R+++ S + P T S + GPP + QG+ KL +
Sbjct: 194 ----DRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLTKLHQLAMQQ 249
Query: 477 ----------------------ENFFGPKEEVKLETH-IRVPASAAGRVIGKGGKTVNEL 513
+ ++G + +H + +P G +IG+ G +NE+
Sbjct: 250 SHFPMTHGNTGFSGIESSSPEVKGYWGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEI 309
Query: 514 QNLTAAEVVVPRDQTPDENDQVIV 537
+ ++ A++ + + QV +
Sbjct: 310 RQMSGAQIKIANPVEGSTDRQVTI 333
Score = 52.4 bits (124), Expect = 1e-06
Identities = 69/285 (24%), Positives = 112/285 (39%), Gaps = 31/285 (10%)
Query: 196 IPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGCSS 255
+ LRL+VP G++IGK G I+ I + T +++ V + E+AI++ P+
Sbjct: 98 VTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIE 157
Query: 256 ACKMILEIMHKEAKDTKTADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTET--KITIS 313
K I +M + T P + F G G++ D+ + T S
Sbjct: 158 CVKQICVVMLESPPKGVTIPYRPKPSSSPVIFAG------GQDRYSTGSDSASFPHTTPS 211
Query: 314 SLQDLTLYNPE-RTITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAA 372
+ L P T++G Q + K+ + +++Q P +
Sbjct: 212 MCLNPDLEGPPLEAYTIQGQYA----IPQPDLTKLHQ--------LAMQQSHFP-MTHGN 258
Query: 373 VGLFPASSSAVPPPPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLS 432
G SS+ V G + Q E+ IP +G IIG++G I ++
Sbjct: 259 TGFSGIESSS-----PEVKGYWGLDASAQTTSHELT---IPNDLIGCIIGRQGAKINEIR 310
Query: 433 RFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEE 477
+ + A IKIA P S R V ITG + AQ I +L E
Sbjct: 311 QMSGAQIKIANP-VEGSTDRQVTITGSAASISLAQYLINVRLSSE 354
>gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens]
Length = 365
Score = 70.5 bits (171), Expect = 4e-12
Identities = 42/134 (31%), Positives = 70/134 (52%), Gaps = 8/134 (5%)
Query: 408 VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQ 467
+++ + + VG+IIGKKG+ +K++ + A I I+ P+ R++ + GP A FKA
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPE---RIITLAGPTNAIFKAF 72
Query: 468 GRIYGKLKEENFFGPKEEVK-----LETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVV 522
I KL+E+ + + VPAS G +IGKGG + E++ T A+V
Sbjct: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQ 132
Query: 523 VPRDQTPDENDQVI 536
V D P+ ++ I
Sbjct: 133 VAGDMLPNSTERAI 146
Score = 56.6 bits (135), Expect = 6e-08
Identities = 75/384 (19%), Positives = 150/384 (39%), Gaps = 98/384 (25%)
Query: 194 VDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGC 253
V + +RLL+ + VG+IIGK+G +++ + +++ ++I++ E+ I++
Sbjct: 12 VTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI---SEGNCPERIITLAGPTNAI 68
Query: 254 SSACKMILEIMHKEAKDTKT------ADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTE 307
A MI++ + ++ + T V L+++ + G LIGK G +K++ + T
Sbjct: 69 FKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTG 128
Query: 308 TKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPG 367
++ ++ D+ + ER IT+ G Q I++ V++
Sbjct: 129 AQVQVAG--DMLPNSTERAITIAG-------IPQSIIECVKQ------------------ 161
Query: 368 LNLAAVGLFPASSSAVPPPPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQH 427
+ V L S S PP VT PY P + +I GQ
Sbjct: 162 --ICVVMLETLSQS----PPKGVT--IPYR---------------PKPSSSPVIFAGGQ- 197
Query: 428 IKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRI------YGKLKE----- 476
R+++ S + P T S + GPP + QG+ KL +
Sbjct: 198 ----DRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLTKLHQLAMQQ 253
Query: 477 ----------------------ENFFGPKEEVKLETH-IRVPASAAGRVIGKGGKTVNEL 513
+ ++G + +H + +P G +IG+ G +NE+
Sbjct: 254 SHFPMTHGNTGFSGIESSSPEVKGYWGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEI 313
Query: 514 QNLTAAEVVVPRDQTPDENDQVIV 537
+ ++ A++ + + QV +
Sbjct: 314 RQMSGAQIKIANPVEGSTDRQVTI 337
Score = 50.1 bits (118), Expect = 6e-06
Identities = 69/289 (23%), Positives = 114/289 (39%), Gaps = 35/289 (12%)
Query: 196 IPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGC-- 253
+ LRL+VP G++IGK G I+ I + T +++ V + E+AI++ P+
Sbjct: 98 VTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIE 157
Query: 254 --SSACKMILEIMHKEAKDTKTADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTET--K 309
C ++LE + + T P + F G G++ D+ +
Sbjct: 158 CVKQICVVMLETLSQSPPKGVTIPYRPKPSSSPVIFAG------GQDRYSTGSDSASFPH 211
Query: 310 ITISSLQDLTLYNPE-RTITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGL 368
T S + L P T++G Q + K+ + +++Q P +
Sbjct: 212 TTPSMCLNPDLEGPPLEAYTIQGQYA----IPQPDLTKLHQ--------LAMQQSHFP-M 258
Query: 369 NLAAVGLFPASSSAVPPPPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHI 428
G SS+ V G + Q E+ IP +G IIG++G I
Sbjct: 259 THGNTGFSGIESSS-----PEVKGYWGLDASAQTTSHELT---IPNDLIGCIIGRQGAKI 310
Query: 429 KQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEE 477
++ + + A IKIA P S R V ITG + AQ I +L E
Sbjct: 311 NEIRQMSGAQIKIANP-VEGSTDRQVTITGSAASISLAQYLINVRLSSE 358
>gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens]
Length = 362
Score = 70.5 bits (171), Expect = 4e-12
Identities = 42/134 (31%), Positives = 70/134 (52%), Gaps = 8/134 (5%)
Query: 408 VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQ 467
+++ + + VG+IIGKKG+ +K++ + A I I+ P+ R++ + GP A FKA
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPE---RIITLAGPTNAIFKAF 72
Query: 468 GRIYGKLKEENFFGPKEEVK-----LETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVV 522
I KL+E+ + + VPAS G +IGKGG + E++ T A+V
Sbjct: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQ 132
Query: 523 VPRDQTPDENDQVI 536
V D P+ ++ I
Sbjct: 133 VAGDMLPNSTERAI 146
Score = 58.2 bits (139), Expect = 2e-08
Identities = 44/184 (23%), Positives = 80/184 (43%), Gaps = 45/184 (24%)
Query: 279 LKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCR 338
+++L H VG +IGK+G ++KK+ +++ +I IS PER IT+ G +
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAIFK 70
Query: 339 AEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSS 398
A I+ K+ E + + +S+A PP +
Sbjct: 71 AFAMIIDKLEEDISSSM----------------------TNSTAASRPPVT--------- 99
Query: 399 FMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITG 458
+++ +PA G++IGK G IK++ A +++A P+S R + I G
Sbjct: 100 ---------LRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAG 150
Query: 459 PPEA 462
P++
Sbjct: 151 IPQS 154
Score = 55.1 bits (131), Expect = 2e-07
Identities = 35/156 (22%), Positives = 80/156 (51%), Gaps = 11/156 (7%)
Query: 194 VDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGC 253
V + +RLL+ + VG+IIGK+G +++ + +++ ++I++ E+ I++
Sbjct: 12 VTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI---SEGNCPERIITLAGPTNAI 68
Query: 254 SSACKMILEIMHKEAKDTKT------ADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTE 307
A MI++ + ++ + T V L+++ + G LIGK G +K++ + T
Sbjct: 69 FKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTG 128
Query: 308 TKITISSLQDLTLYNPERTITVKGAIENCCRAEQEI 343
++ ++ D+ + ER IT+ G ++ ++I
Sbjct: 129 AQVQVAG--DMLPNSTERAITIAGIPQSIIECVKQI 162
Score = 42.7 bits (99), Expect = 0.001
Identities = 21/69 (30%), Positives = 36/69 (52%)
Query: 196 IPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGCSS 255
+ LRL+VP G++IGK G I+ I + T +++ V + E+AI++ P+
Sbjct: 98 VTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIE 157
Query: 256 ACKMILEIM 264
K I +M
Sbjct: 158 CVKQICVVM 166
Score = 38.5 bits (88), Expect = 0.017
Identities = 25/69 (36%), Positives = 36/69 (52%), Gaps = 1/69 (1%)
Query: 409 QVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQG 468
++ IP +G IIG++G I ++ + + A IKIA P S R V ITG + AQ
Sbjct: 288 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANP-VEGSTDRQVTITGSAASISLAQY 346
Query: 469 RIYGKLKEE 477
I +L E
Sbjct: 347 LINVRLSSE 355
Score = 30.4 bits (67), Expect = 4.6
Identities = 29/130 (22%), Positives = 55/130 (42%), Gaps = 10/130 (7%)
Query: 131 QTRQAIMKLNGHQLENHALKVSYIPDEQIAQGPENGRRGGFGSRGQPRQGSPVAAGAPAK 190
Q + AI + + +L A++ S+ P +G G G + AG A
Sbjct: 229 QGQYAIPQPDLTKLHQLAMQQSHFP-------MTHGNTGFSGIESSSPEVKGYWAGLDAS 281
Query: 191 QQQVDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTP 250
Q L +P +G IIG++GA I I + + ++I + G+ ++ +++ +
Sbjct: 282 AQTTSH--ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE-GSTDRQVTITGSA 338
Query: 251 EGCSSACKMI 260
S A +I
Sbjct: 339 ASISLAQYLI 348
>gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens]
Length = 366
Score = 70.5 bits (171), Expect = 4e-12
Identities = 42/134 (31%), Positives = 70/134 (52%), Gaps = 8/134 (5%)
Query: 408 VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQ 467
+++ + + VG+IIGKKG+ +K++ + A I I+ P+ R++ + GP A FKA
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPE---RIITLAGPTNAIFKAF 72
Query: 468 GRIYGKLKEENFFGPKEEVK-----LETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVV 522
I KL+E+ + + VPAS G +IGKGG + E++ T A+V
Sbjct: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQ 132
Query: 523 VPRDQTPDENDQVI 536
V D P+ ++ I
Sbjct: 133 VAGDMLPNSTERAI 146
Score = 55.5 bits (132), Expect = 1e-07
Identities = 75/385 (19%), Positives = 145/385 (37%), Gaps = 99/385 (25%)
Query: 194 VDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGC 253
V + +RLL+ + VG+IIGK+G +++ + +++ ++I++ E+ I++
Sbjct: 12 VTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI---SEGNCPERIITLAGPTNAI 68
Query: 254 SSACKMILEIMHKEAKDTKT------ADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTE 307
A MI++ + ++ + T V L+++ + G LIGK G +K++ + T
Sbjct: 69 FKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTG 128
Query: 308 TKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPG 367
++ ++ D+ + ER IT+ G Q I++ V++
Sbjct: 129 AQVQVAG--DMLPNSTERAITIAG-------IPQSIIECVKQ------------------ 161
Query: 368 LNLAAVGLFPASSSAVPPPPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQH 427
+ V L S S PP VT PY P + +I GQ
Sbjct: 162 --ICVVMLETLSQS----PPKGVT--IPYR---------------PKPSSSPVIFAGGQ- 197
Query: 428 IKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQGR------------------ 469
R+++ S + P T S + GPP + QG+
Sbjct: 198 ----DRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLTKLHQLAMQQ 253
Query: 470 -----IYGKLKEENFFGPKEEVK------------LETHIRVPASAAGRVIGKGGKTVNE 512
+G EVK + +P G +IG+ G +NE
Sbjct: 254 SHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINE 313
Query: 513 LQNLTAAEVVVPRDQTPDENDQVIV 537
++ ++ A++ + + QV +
Sbjct: 314 IRQMSGAQIKIANPVEGSTDRQVTI 338
Score = 49.3 bits (116), Expect = 1e-05
Identities = 70/289 (24%), Positives = 115/289 (39%), Gaps = 34/289 (11%)
Query: 196 IPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGC-- 253
+ LRL+VP G++IGK G I+ I + T +++ V + E+AI++ P+
Sbjct: 98 VTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIE 157
Query: 254 --SSACKMILEIMHKEAKDTKTADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTET--K 309
C ++LE + + T P + F G G++ D+ +
Sbjct: 158 CVKQICVVMLETLSQSPPKGVTIPYRPKPSSSPVIFAG------GQDRYSTGSDSASFPH 211
Query: 310 ITISSLQDLTLYNPE-RTITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGL 368
T S + L P T++G Q + K+ + AM QSH
Sbjct: 212 TTPSMCLNPDLEGPPLEAYTIQGQYA----IPQPDLTKLHQL------AMQ-QSHFPMTH 260
Query: 369 NLAAVGLFPASSSAVPPPPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHI 428
+SS V + + +A +S ++ IP +G IIG++G I
Sbjct: 261 GNTGFSGIESSSPEVKGYWAGLDASAQTTSH---------ELTIPNDLIGCIIGRQGAKI 311
Query: 429 KQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEE 477
++ + + A IKIA P S R V ITG + AQ I +L E
Sbjct: 312 NEIRQMSGAQIKIANP-VEGSTDRQVTITGSAASISLAQYLINVRLSSE 359
Score = 30.4 bits (67), Expect = 4.6
Identities = 29/130 (22%), Positives = 55/130 (42%), Gaps = 10/130 (7%)
Query: 131 QTRQAIMKLNGHQLENHALKVSYIPDEQIAQGPENGRRGGFGSRGQPRQGSPVAAGAPAK 190
Q + AI + + +L A++ S+ P +G G G + AG A
Sbjct: 233 QGQYAIPQPDLTKLHQLAMQQSHFP-------MTHGNTGFSGIESSSPEVKGYWAGLDAS 285
Query: 191 QQQVDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTP 250
Q L +P +G IIG++GA I I + + ++I + G+ ++ +++ +
Sbjct: 286 AQTTSH--ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE-GSTDRQVTITGSA 342
Query: 251 EGCSSACKMI 260
S A +I
Sbjct: 343 ASISLAQYLI 352
>gi|154355000 KH-type splicing regulatory protein [Homo sapiens]
Length = 711
Score = 69.3 bits (168), Expect = 9e-12
Identities = 53/185 (28%), Positives = 91/185 (49%), Gaps = 17/185 (9%)
Query: 403 PEQEMVQVF-IPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPE 461
P M + + +P VG IIG+ G+ I ++ + + ++I+P ++ R V +TG PE
Sbjct: 141 PRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISP-DSGGLPERSVSLTGAPE 199
Query: 462 AQFKAQ-----------GRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTV 510
+ KA+ G G+ + G V+ I +PA AG VIGKGG+T+
Sbjct: 200 SVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQ---EIMIPAGKAGLVIGKGGETI 256
Query: 511 NELQNLTAAEVVVPRDQTPDENDQVIVKIIGHFYASQMAQRKIRDILAQVKQQHQKGQSN 570
+LQ ++++ +D + + N ++IIG Y Q A + DIL + + Q G N
Sbjct: 257 KQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDILRE-RDQGGFGDRN 315
Query: 571 QAQAR 575
+ +R
Sbjct: 316 EYGSR 320
Score = 60.8 bits (146), Expect = 3e-09
Identities = 95/408 (23%), Positives = 163/408 (39%), Gaps = 65/408 (15%)
Query: 162 GPENGRRGGFGSRGQPRQGSPVAAGAPAKQQQVDIPLRLLVPTQYVGAIIGKEGATIRNI 221
GP G GG GS G P Q P G P ++ D + + + A IG + AT N
Sbjct: 44 GPGGGGPGG-GSAGGPSQ--PPGGGGPGIRK--DAFADAVQRARQIAAKIGGDAATTVNN 98
Query: 222 TKQTQSKIDVHRKENAGAAEKAISVHSTPEGCSSACKMILEIMHKEAKDTKTAD-EVPLK 280
+ R+ G ++ + S + SS L +H + + T + VP
Sbjct: 99 STPDFGFGGQKRQLEDGDQPESKKLASQGDSISSQ----LGPIHPPPRTSMTEEYRVP-- 152
Query: 281 ILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCRAE 340
+ VG +IG+ G + K++QD+ K+ IS PER++++ GA E+ +A+
Sbjct: 153 ----DGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGL---PERSVSLTGAPESVQKAK 205
Query: 341 QEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSSFM 400
+ +D+ S PP + +
Sbjct: 206 MML---------DDIV-----------------------SRGRGGPPGQF-----HDNAN 228
Query: 401 QAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKV-RMVIITGP 459
+ ++ IPA G +IGK G+ IKQL A + + + ++ V + + I G
Sbjct: 229 GGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGD 288
Query: 460 PEAQFKAQGRIYGKLKE--ENFFGPKEE----VKLETHIRVPASAAGRVIGKGGKTVNEL 513
P +A + L+E + FG + E + + VP + G VIG+ G+ + ++
Sbjct: 289 PYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKI 348
Query: 514 QNLTAAEVVVPRDQTPDENDQVIVKIIGHFYASQMAQRKIRDILAQVK 561
QN A V + Q + I I+G + A R I D+L ++
Sbjct: 349 QN--DAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLR 394
Score = 60.8 bits (146), Expect = 3e-09
Identities = 74/322 (22%), Positives = 130/322 (40%), Gaps = 48/322 (14%)
Query: 173 SRGQPRQGSPVAAGAPAKQQQVDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVH 232
SRG R G P A Q +++P G +IGK G TI+ + ++ K+ +
Sbjct: 213 SRG--RGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILI 270
Query: 233 RKENAGA-AEKAISVHSTPEGCSSACKMILEIMHKEAK---------DTKTADEVPLKIL 282
+ + +K + + P AC+M+++I+ + + ++ + + +
Sbjct: 271 QDGSQNTNVDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVP 330
Query: 283 AHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCRAEQE 342
H+ VG +IG+ G +KK++ D +I D T PE+ + G + C A +
Sbjct: 331 RHS--VGVVIGRSGEMIKKIQNDAGVRIQFKQ-DDGT--GPEKIAHIMGPPDRCEHAARI 385
Query: 343 IMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSSFMQA 402
I ND+ SL+S P P P G
Sbjct: 386 I---------NDL-LQSLRSG-------------PPGPPGGPGMPPGGRGRGRGQGNWGP 422
Query: 403 PEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAP--PETPDSKVRMVIITGPP 460
P EM IP G +IG+ G+++K +++ A ++I+ P D ++ II G P
Sbjct: 423 PGGEMT-FSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSP 481
Query: 461 EAQFKAQGRIYGKLKEENFFGP 482
+ A+ +L EE GP
Sbjct: 482 QQIDHAK-----QLIEEKIEGP 498
Score = 59.7 bits (143), Expect = 7e-09
Identities = 84/402 (20%), Positives = 149/402 (37%), Gaps = 93/402 (23%)
Query: 202 VPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGCSSACKMIL 261
VP VG IIG+ G I I + + K+ + ++ G E+++S+ PE A M+
Sbjct: 151 VPDGMVGLIIGRGGEQINKIQQDSGCKVQIS-PDSGGLPERSVSLTGAPESVQKAKMMLD 209
Query: 262 EIM-----------HKEAKDTKTADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKI 310
+I+ H A + + I A G +IGK G +K++++ K+
Sbjct: 210 DIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPAGK--AGLVIGKGGETIKQLQERAGVKM 267
Query: 311 TI--SSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGL 368
+ Q+ + P R I ++ C +I++ E D ++
Sbjct: 268 ILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDILR------ERDQGGFGDRNEY---- 317
Query: 369 NLAAVGLFPASSSAVPPPPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHI 428
S + G + V +P +VG +IG+ G+ I
Sbjct: 318 ------------------GSRIGGG--------------IDVPVPRHSVGVVIGRSGEMI 345
Query: 429 KQLSRFASASIK---------------IAPPETPDSKVRMV------IITGPPEAQ---- 463
K++ A I+ + PP+ + R++ + +GPP
Sbjct: 346 KKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPG 405
Query: 464 FKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVV 523
GR G+ + + +GP E +P G VIG+GG+ V + T A V +
Sbjct: 406 MPPGGR--GRGRGQGNWGPPGG---EMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEI 460
Query: 524 PRDQTPDENDQVIVKIIGHF-----YASQMAQRKIRDILAQV 560
R P+ + + II +A Q+ + KI L V
Sbjct: 461 SRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPV 502
Score = 32.0 bits (71), Expect = 1.6
Identities = 28/104 (26%), Positives = 46/104 (44%), Gaps = 12/104 (11%)
Query: 162 GPENGRRGGFGSRGQPR-QGSPVAAGAPAKQQQVDIPLRLLVPTQYVGAIIGKEGATIRN 220
GP G G RG+ R QG+ G P + IP T G +IG+ G ++
Sbjct: 399 GPPGGPGMPPGGRGRGRGQGN---WGPPGGEMTFSIP------THKCGLVIGRGGENVKA 449
Query: 221 ITKQTQSKIDVHRK--ENAGAAEKAISVHSTPEGCSSACKMILE 262
I +QT + +++ R+ N K + +P+ A ++I E
Sbjct: 450 INQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEE 493
>gi|17402900 far upstream element-binding protein [Homo sapiens]
Length = 644
Score = 68.2 bits (165), Expect = 2e-11
Identities = 90/390 (23%), Positives = 159/390 (40%), Gaps = 87/390 (22%)
Query: 202 VPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGCSSACKMIL 261
VP VG IIG+ G I I +++ KI + ++ G E++ + TPE SA +++
Sbjct: 107 VPDGMVGFIIGRGGEQISRIQQESGCKIQI-APDSGGLPERSCMLTGTPESVQSAKRLLD 165
Query: 262 EIMHK--EAKDTKTAD---EVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQ 316
+I+ K A D +I+ + G +IGK G +K++++ K+ + +Q
Sbjct: 166 QIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVM--IQ 223
Query: 317 DLTLYNPERT-----ITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLA 371
D P+ T + + G +A++ +++ +R+
Sbjct: 224 D----GPQNTGADKPLRITGDPYKVQQAKEMVLELIRDQ--------------------- 258
Query: 372 AVGLFPASSSAVPPPPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQL 431
V S G E + V IP AVG +IG+ G+ IK++
Sbjct: 259 ------GGFREVRNEYGSRIGG-----------NEGIDVPIPRFAVGIVIGRNGEMIKKI 301
Query: 432 SRFASASIKIAPPE--TPDSKVRMVIITGPPE-AQFKAQ--------------------G 468
A I+ P + TP+ R+ ITGPP+ Q A+ G
Sbjct: 302 QNDAGVRIQFKPDDGTTPE---RIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPGPGG 358
Query: 469 RIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQT 528
R G+ + GP ++ E + VP G +IGKGG+T+ + + A + + R+
Sbjct: 359 RGRGRGQGNWNMGPPGGLQ-EFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPP 417
Query: 529 PDENDQVIVKIIGHF-----YASQMAQRKI 553
P+ + + + I YA Q+ + KI
Sbjct: 418 PNADPNMKLFTIRGTPQQIDYARQLIEEKI 447
Score = 67.4 bits (163), Expect = 3e-11
Identities = 69/295 (23%), Positives = 121/295 (41%), Gaps = 46/295 (15%)
Query: 200 LLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHR--KENAGAAEKAISVHSTPEGCSSAC 257
+++P G +IGK G TI+ + ++ K+ + + +N G A+K + + P A
Sbjct: 190 IMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTG-ADKPLRITGDPYKVQQAK 248
Query: 258 KMILEIMHKEAKDTKTADEVPLKILAHNNF--------VGRLIGKEGRNLKKVEQDTETK 309
+M+LE++ + + +E +I + VG +IG+ G +KK++ D +
Sbjct: 249 EMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVR 308
Query: 310 ITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLN 369
I T PER + G + C A + I +R + PG
Sbjct: 309 IQFKPDDGTT---PERIAQITGPPDRCQHAAEIITDLLRSVQAGNPGG--------PGPG 357
Query: 370 LAAVGLFPASSSAVPPPPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIK 429
G + + PP G +F+ +P G IIGK G+ IK
Sbjct: 358 GRGRGRGQGNWNMGPP------GGLQEFNFI-----------VPTGKTGLIIGKGGETIK 400
Query: 430 QLSRFASASIKIA--PPETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEENFFGP 482
+S+ + A I++ PP D +++ I G P+ A+ +L EE GP
Sbjct: 401 SISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYAR-----QLIEEKIGGP 450
Score = 63.9 bits (154), Expect = 4e-10
Identities = 45/154 (29%), Positives = 81/154 (52%), Gaps = 13/154 (8%)
Query: 412 IPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIY 471
+P VG IIG+ G+ I ++ + + I+IAP ++ R ++TG PE+ A+ R+
Sbjct: 107 VPDGMVGFIIGRGGEQISRIQQESGCKIQIAP-DSGGLPERSCMLTGTPESVQSAK-RLL 164
Query: 472 GKLKEE--------NFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVV 523
++ E+ + GP V+ I +PAS AG VIGKGG+T+ +LQ ++V+
Sbjct: 165 DQIVEKGRPAPGFHHGDGPGNAVQ---EIMIPASKAGLVIGKGGETIKQLQERAGVKMVM 221
Query: 524 PRDQTPDENDQVIVKIIGHFYASQMAQRKIRDIL 557
+D + ++I G Y Q A+ + +++
Sbjct: 222 IQDGPQNTGADKPLRITGDPYKVQQAKEMVLELI 255
Score = 53.1 bits (126), Expect = 7e-07
Identities = 72/326 (22%), Positives = 126/326 (38%), Gaps = 70/326 (21%)
Query: 264 MHKEAKDTKTADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNP 323
MH++ + +E + + VG +IG+ G + +++Q++ KI I+ P
Sbjct: 92 MHQQQSRSVMTEEYKVP----DGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGL---P 144
Query: 324 ERTITVKG---AIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASS 380
ER+ + G ++++ R +I++K R A PG +
Sbjct: 145 ERSCMLTGTPESVQSAKRLLDQIVEKGRPA---------------PGFHHG--------- 180
Query: 381 SAVPPPPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASAS-- 438
P + ++ IPA G +IGK G+ IKQL A
Sbjct: 181 --------------------DGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMV 220
Query: 439 -IKIAPPETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEE-------NFFGPKEEVKLET 490
I+ P T K + ITG P +A+ + ++++ N +G +
Sbjct: 221 MIQDGPQNTGADK--PLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGI 278
Query: 491 HIRVPASAAGRVIGKGGKTVNELQNLTAAEV-VVPRDQTPDENDQVIVKIIGHFYASQMA 549
+ +P A G VIG+ G+ + ++QN + P D T E I +I G Q A
Sbjct: 279 DVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPER---IAQITGPPDRCQHA 335
Query: 550 QRKIRDILAQVKQQHQKGQSNQAQAR 575
I D+L V+ + G + R
Sbjct: 336 AEIITDLLRSVQAGNPGGPGPGGRGR 361
Score = 45.4 bits (106), Expect = 1e-04
Identities = 31/95 (32%), Positives = 49/95 (51%), Gaps = 6/95 (6%)
Query: 170 GFGSRGQPRQGSPVAAGAPAKQQQVDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKI 229
G G RG+ R G P Q+ + +VPT G IIGK G TI++I++Q+ ++I
Sbjct: 355 GPGGRGRGRGQGNWNMGPPGGLQEFNF----IVPTGKTGLIIGKGGETIKSISQQSGARI 410
Query: 230 DVHRK--ENAGAAEKAISVHSTPEGCSSACKMILE 262
++ R NA K ++ TP+ A ++I E
Sbjct: 411 ELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEE 445
>gi|56549653 neuro-oncological ventral antigen 1 isoform 1 [Homo
sapiens]
Length = 507
Score = 67.0 bits (162), Expect = 4e-11
Identities = 53/200 (26%), Positives = 94/200 (47%), Gaps = 8/200 (4%)
Query: 279 LKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCR 338
LK+L + G +IGK G+ + +++++T I +S +D ER ++G +E
Sbjct: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
Query: 339 AEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSS 398
I +K+RE +N VA S L P + P P + T ++P S
Sbjct: 112 VHGFIAEKIREMPQN-VAKTEPVSILQPQTTVN-----PDRIKQTLPSSPTTTKSSP-SD 164
Query: 399 FMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIA-PPETPDSKVRMVIIT 457
M V++ +P G IIGK G +K + + A ++++ P+ + + R+V ++
Sbjct: 165 PMTTSRANQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVS 224
Query: 458 GPPEAQFKAQGRIYGKLKEE 477
G PE KA I K++E+
Sbjct: 225 GEPEQNRKAVELIIQKIQED 244
Score = 53.9 bits (128), Expect = 4e-07
Identities = 72/329 (21%), Positives = 131/329 (39%), Gaps = 56/329 (17%)
Query: 198 LRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRK-ENAGAAEKAISVHSTPEGCSSA 256
++++VP G IIGK GAT++ + +Q+ + + + +K + E+ ++V PE A
Sbjct: 174 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 233
Query: 257 CKMILEIMHKEAKD-------------------------TKTADEVPLK-----ILAHNN 286
++I++ + ++ + TA+ +P +L H N
Sbjct: 234 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHAN 293
Query: 287 FVGR------LIGKEGRNLKKVEQDTETKITIS-SLQDLTLYNPERTITVKGAIENCCRA 339
G L G G +L + T + +L L L + T A
Sbjct: 294 LAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAASAN 353
Query: 340 EQEIMKKVREAYENDVAAMSLQSHLIPGL----NLAAV-----GLFPASSSAVPPPPSSV 390
+ Y ++ +A + G +LAA G F A+S P S++
Sbjct: 354 PAAAAANLLATYASEASASGSTAGGTAGTFALGSLAAATAATNGYFGAAS---PLAASAI 410
Query: 391 TGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPE--TPD 448
G + +++V++ +P VGAI+GK G+ + + A I+I+ P
Sbjct: 411 LGTEKSTD----GSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPG 466
Query: 449 SKVRMVIITGPPEAQFKAQGRIYGKLKEE 477
++ R V ITG P A AQ I ++ E
Sbjct: 467 TRNRKVTITGTPAATQAAQYLITQRITYE 495
Score = 52.0 bits (123), Expect = 1e-06
Identities = 65/293 (22%), Positives = 112/293 (38%), Gaps = 70/293 (23%)
Query: 173 SRGQPRQGSPVAAGAPAKQQQVDIP--LRLLVPTQYVGAIIGKEGATIRNITKQTQSKID 230
SR +P + P A D L++L+P+ G+IIGK G TI + K+T + I
Sbjct: 25 SRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIK 84
Query: 231 VHRKEN--AGAAEKAISVHSTPEGCSSA----CKMILEIMHKEAK--------------- 269
+ + ++ G E+ + T E ++ + I E+ AK
Sbjct: 85 LSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNP 144
Query: 270 ------------DTKTADEVPL--------KILAHNNFVGRLIGKEGRNLKKVEQDTETK 309
TK++ P+ KI+ N+ G +IGK G +K V + +
Sbjct: 145 DRIKQTLPSSPTTTKSSPSDPMTTSRANQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAW 204
Query: 310 ITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLN 369
+ +S D + ER +TV G E +A + I++K++E
Sbjct: 205 VQLSQKPD-GINLQERVVTVSGEPEQNRKAVELIIQKIQED------------------- 244
Query: 370 LAAVGLFPASSSAVPPPPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIG 422
P S S + ++VTG S+ +P +V A A ++G
Sbjct: 245 -------PQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLG 290
Score = 51.6 bits (122), Expect = 2e-06
Identities = 50/203 (24%), Positives = 84/203 (41%), Gaps = 43/203 (21%)
Query: 405 QEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPET--PDSKVRMVIITGPPEA 462
Q ++V IP+ A G+IIGK GQ I QL + A+IK++ + P + R+ +I G EA
Sbjct: 49 QYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEA 108
Query: 463 QFKAQGRIYGKLKE----------ENFFGPKEEVK------------------------- 487
G I K++E + P+ V
Sbjct: 109 LNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTT 168
Query: 488 ---LETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQVIVKIIGHFY 544
+ I VP S AG +IGKGG TV + + A V + + + +V + G
Sbjct: 169 SRANQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGE-- 226
Query: 545 ASQMAQRKIRDILAQVKQQHQKG 567
+ ++ + I+ ++++ Q G
Sbjct: 227 -PEQNRKAVELIIQKIQEDPQSG 248
Score = 38.5 bits (88), Expect = 0.017
Identities = 26/83 (31%), Positives = 42/83 (50%), Gaps = 14/83 (16%)
Query: 445 ETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIG 504
+ PDS+ R + PPEA G K N E+ + + +P+ AAG +IG
Sbjct: 21 DPPDSRKRP--LEAPPEA---------GSTKRTN---TGEDGQYFLKVLIPSYAAGSIIG 66
Query: 505 KGGKTVNELQNLTAAEVVVPRDQ 527
KGG+T+ +LQ T A + + + +
Sbjct: 67 KGGQTIVQLQKETGATIKLSKSK 89
Score = 37.0 bits (84), Expect = 0.049
Identities = 27/77 (35%), Positives = 42/77 (54%), Gaps = 7/77 (9%)
Query: 476 EENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPR--DQTPDEND 533
E++ G K+ V+ I VP + G ++GKGGKT+ E Q LT A + + + + P +
Sbjct: 414 EKSTDGSKDVVE----IAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRN 469
Query: 534 QVIVKIIGHFYASQMAQ 550
+ V I G A+Q AQ
Sbjct: 470 RK-VTITGTPAATQAAQ 485
Score = 35.4 bits (80), Expect = 0.14
Identities = 22/95 (23%), Positives = 42/95 (44%), Gaps = 3/95 (3%)
Query: 170 GFGSRGQPRQGSPVAAGAPAKQQQVDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKI 229
G+ P S + + D+ + + VP VGAI+GK G T+ + T ++I
Sbjct: 397 GYFGAASPLAASAILGTEKSTDGSKDV-VEIAVPENLVGAILGKGGKTLVEYQELTGARI 455
Query: 230 DVHRKEN--AGAAEKAISVHSTPEGCSSACKMILE 262
+ +K G + +++ TP +A +I +
Sbjct: 456 QISKKGEFVPGTRNRKVTITGTPAATQAAQYLITQ 490
Score = 33.5 bits (75), Expect = 0.55
Identities = 25/93 (26%), Positives = 44/93 (47%), Gaps = 3/93 (3%)
Query: 269 KDTKTADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTIT 328
K T + +V ++I N VG ++GK G+ L + ++ T +I IS + R +T
Sbjct: 415 KSTDGSKDV-VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVT 473
Query: 329 VKGAIENCCRAEQEIMKKVREAYENDVAAMSLQ 361
+ G A+ I +++ YE V A + Q
Sbjct: 474 ITGTPAATQAAQYLITQRI--TYEQGVRAANPQ 504
>gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo
sapiens]
Length = 483
Score = 61.2 bits (147), Expect = 2e-09
Identities = 50/179 (27%), Positives = 84/179 (46%), Gaps = 19/179 (10%)
Query: 405 QEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPET--PDSKVRMVIITGPPEA 462
Q ++V IP+ A G+IIGK GQ I QL + A+IK++ + P + R+ +I G EA
Sbjct: 49 QYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEA 108
Query: 463 QFKAQGRIYGKLKE----------ENFFGPKEEVK----LETHIRVPASAAGRVIGKGGK 508
G I K++E + P+ V + I VP S AG +IGKGG
Sbjct: 109 LNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGA 168
Query: 509 TVNELQNLTAAEVVVPRDQTPDENDQVIVKIIGHFYASQMAQRKIRDILAQVKQQHQKG 567
TV + + A V + + + +V + G + ++ + I+ ++++ Q G
Sbjct: 169 TVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGE---PEQNRKAVELIIQKIQEDPQSG 224
Score = 60.5 bits (145), Expect = 4e-09
Identities = 61/269 (22%), Positives = 109/269 (40%), Gaps = 46/269 (17%)
Query: 173 SRGQPRQGSPVAAGAPAKQQQVDIP--LRLLVPTQYVGAIIGKEGATIRNITKQTQSKID 230
SR +P + P A D L++L+P+ G+IIGK G TI + K+T + I
Sbjct: 25 SRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIK 84
Query: 231 VHRKEN--AGAAEKAISVHSTPEGCSSACKMILEIMHKEAKDTKTADEVPL--------- 279
+ + ++ G E+ + T E ++ I E + + ++ + V +
Sbjct: 85 LSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNP 144
Query: 280 ------KILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAI 333
KI+ N+ G +IGK G +K V + + + +S D + ER +TV G
Sbjct: 145 DRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPD-GINLQERVVTVSGEP 203
Query: 334 ENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGA 393
E +A + I++K++E P S S + ++VTG
Sbjct: 204 EQNRKAVELIIQKIQED--------------------------PQSGSCLNISYANVTGP 237
Query: 394 APYSSFMQAPEQEMVQVFIPAQAVGAIIG 422
S+ +P +V A A ++G
Sbjct: 238 VANSNPTGSPYANTAEVLPTAAAAAGLLG 266
Score = 53.9 bits (128), Expect = 4e-07
Identities = 72/329 (21%), Positives = 131/329 (39%), Gaps = 56/329 (17%)
Query: 198 LRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRK-ENAGAAEKAISVHSTPEGCSSA 256
++++VP G IIGK GAT++ + +Q+ + + + +K + E+ ++V PE A
Sbjct: 150 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 209
Query: 257 CKMILEIMHKEAKD-------------------------TKTADEVPLK-----ILAHNN 286
++I++ + ++ + TA+ +P +L H N
Sbjct: 210 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHAN 269
Query: 287 FVGR------LIGKEGRNLKKVEQDTETKITIS-SLQDLTLYNPERTITVKGAIENCCRA 339
G L G G +L + T + +L L L + T A
Sbjct: 270 LAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAASAN 329
Query: 340 EQEIMKKVREAYENDVAAMSLQSHLIPGL----NLAAV-----GLFPASSSAVPPPPSSV 390
+ Y ++ +A + G +LAA G F A+S P S++
Sbjct: 330 PAAAAANLLATYASEASASGSTAGGTAGTFALGSLAAATAATNGYFGAAS---PLAASAI 386
Query: 391 TGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPE--TPD 448
G + +++V++ +P VGAI+GK G+ + + A I+I+ P
Sbjct: 387 LGTEKSTD----GSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPG 442
Query: 449 SKVRMVIITGPPEAQFKAQGRIYGKLKEE 477
++ R V ITG P A AQ I ++ E
Sbjct: 443 TRNRKVTITGTPAATQAAQYLITQRITYE 471
Score = 37.0 bits (84), Expect = 0.049
Identities = 27/77 (35%), Positives = 42/77 (54%), Gaps = 7/77 (9%)
Query: 476 EENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPR--DQTPDEND 533
E++ G K+ V+ I VP + G ++GKGGKT+ E Q LT A + + + + P +
Sbjct: 390 EKSTDGSKDVVE----IAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRN 445
Query: 534 QVIVKIIGHFYASQMAQ 550
+ V I G A+Q AQ
Sbjct: 446 RK-VTITGTPAATQAAQ 461
Score = 35.4 bits (80), Expect = 0.14
Identities = 22/95 (23%), Positives = 42/95 (44%), Gaps = 3/95 (3%)
Query: 170 GFGSRGQPRQGSPVAAGAPAKQQQVDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKI 229
G+ P S + + D+ + + VP VGAI+GK G T+ + T ++I
Sbjct: 373 GYFGAASPLAASAILGTEKSTDGSKDV-VEIAVPENLVGAILGKGGKTLVEYQELTGARI 431
Query: 230 DVHRKEN--AGAAEKAISVHSTPEGCSSACKMILE 262
+ +K G + +++ TP +A +I +
Sbjct: 432 QISKKGEFVPGTRNRKVTITGTPAATQAAQYLITQ 466
Score = 33.5 bits (75), Expect = 0.55
Identities = 25/93 (26%), Positives = 44/93 (47%), Gaps = 3/93 (3%)
Query: 269 KDTKTADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTIT 328
K T + +V ++I N VG ++GK G+ L + ++ T +I IS + R +T
Sbjct: 391 KSTDGSKDV-VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVT 449
Query: 329 VKGAIENCCRAEQEIMKKVREAYENDVAAMSLQ 361
+ G A+ I +++ YE V A + Q
Sbjct: 450 ITGTPAATQAAQYLITQRI--TYEQGVRAANPQ 480
>gi|4885409 high density lipoprotein binding protein [Homo sapiens]
Length = 1268
Score = 60.1 bits (144), Expect = 5e-09
Identities = 83/359 (23%), Positives = 142/359 (39%), Gaps = 77/359 (21%)
Query: 200 LLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGCSSACKM 259
L++ ++ IIG++G IR I + I ++ + A ++ I P+ C
Sbjct: 512 LIIEQRFHRTIIGQKGERIREIRDKFPEVI-INFPDPAQKSD--IVQLRGPKNEVEKCTK 568
Query: 260 ILEIMHKEAKDTKTADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLT 319
++ M + + + VP+ H N +IGK G N+KK+ +++ TKI DL
Sbjct: 569 YMQKMVADLVENSYSISVPIFKQFHKN----IIGKGGANIKKIREESNTKI------DLP 618
Query: 320 LYNP-ERTITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPA 378
N TI + G NC A I +S+Q L N+A
Sbjct: 619 AENSNSETIIITGKRANCEAARSRI--------------LSIQKDL---ANIAE------ 655
Query: 379 SSSAVPPPPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASAS 438
V+V IPA+ ++IG KG+ I+ +
Sbjct: 656 -----------------------------VEVSIPAKLHNSLIGTKGRLIRSIMEECGGV 686
Query: 439 IKIAPPETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASA 498
P E S V+I GP KA+ ++ +E K+ IR
Sbjct: 687 HIHFPVEGSGSDT--VVIRGPSSDVEKAKKQLLHLAEE------KQTKSFTVDIRAKPEY 738
Query: 499 AGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQVIVKIIGHFYASQMAQRKIRDIL 557
+IGKGG + ++++ T A V+ P ++ DQ ++ IIG A + AQ+++ ++
Sbjct: 739 HKFLIGKGGGKIRKVRDSTGARVIFP---AAEDKDQDLITIIGKEDAVREAQKELEALI 794
Score = 58.2 bits (139), Expect = 2e-08
Identities = 87/394 (22%), Positives = 162/394 (41%), Gaps = 51/394 (12%)
Query: 193 QVDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEG 252
Q + +P ++ +IGK G ++++ +T +KI + R ++ I + T EG
Sbjct: 148 QTQASATVAIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDD---PSNQIKITGTKEG 204
Query: 253 CSSACKMILEIMHKEAKDTKTADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITI 312
A +L I A+ K A E ++ F + G R + ++ Q+T T+I I
Sbjct: 205 IEKARHEVLLI---SAEQDKRAVE---RLEVEKAFHPFIAGPYNRLVGEIMQETGTRINI 258
Query: 313 SSLQDLTLYNPERT-ITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQ------SHLI 365
+ RT I G E +A I KK+ E + ++++ ++I
Sbjct: 259 PP------PSVNRTEIVFTGEKEQLAQAVARI-KKIYEEKKKKTTTIAVEVKKSQHKYVI 311
Query: 366 -PGLNLAAVGLFPASSSAVPPPPSSVT------------GAAPYSSFMQAPEQEMVQVFI 412
P N L S PP S++ G A + +A + V
Sbjct: 312 GPKGNSLQEILERTGVSVEIPPSDSISETVILRGEPEKLGQALTEVYAKANSFTVSSVAA 371
Query: 413 PAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIYG 472
P+ IIGKKGQ++ ++++ + I E D + + GP E AQ +I G
Sbjct: 372 PSWLHRFIIGKKGQNLAKITQ-QMPKVHIEFTEGEDK----ITLEGPTEDVNVAQEQIEG 426
Query: 473 KLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDEN 532
+K+ + V+ I + +IGK G +N +++ V +P PD
Sbjct: 427 MVKD--LINRMDYVE----INIDHKFHRHLIGKSGANINRIKDQYKVSVRIP----PDSE 476
Query: 533 DQVIVKIIGHFYASQMAQRKIRDILAQVKQQHQK 566
+++I G Q A+R++ ++ ++++ + K
Sbjct: 477 KSNLIRIEGDPQGVQQAKRELLELASRMENERTK 510
Score = 47.0 bits (110), Expect = 5e-05
Identities = 53/218 (24%), Positives = 89/218 (40%), Gaps = 26/218 (11%)
Query: 198 LRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGCSSAC 257
L + V +Y IIG++GA I I + I K++ + I++ + +A
Sbjct: 1055 LSVTVDPKYHPKIIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQITITGYEKNTEAAR 1114
Query: 258 KMILEIMHKEAKDTKTADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITI--SSL 315
IL I+ + + +++VPL H R+IG G+ ++K+ + + I S
Sbjct: 1115 DAILRIVGE--LEQMVSEDVPLDHRVH----ARIIGARGKAIRKIMDEFKVDIRFPQSGA 1168
Query: 316 QDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGL 375
D +TV G EN A I+ E + V + +LQ ++ P
Sbjct: 1169 PD------PNCVTVTGLPENVEEAIDHILNLEEEYLADVVDSEALQVYMKP--------- 1213
Query: 376 FPASSSAVPPPPSSVTGAAPY--SSFMQAPEQEMVQVF 411
PA A P V AP+ SS +AP+ + F
Sbjct: 1214 -PAHEEAKAPSRGFVVRDAPWTASSSEKAPDMSSSEEF 1250
Score = 40.0 bits (92), Expect = 0.006
Identities = 73/363 (20%), Positives = 135/363 (37%), Gaps = 84/363 (23%)
Query: 193 QVDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKID--------VHR-----KENAGA 239
+ + L +P ++ +++G +G+ I+ IT+ +I VH +EN
Sbjct: 871 EAQVTLECAIPQKFHRSVMGPKGSRIQQITRDFSVQIKFPDREENAVHSTEPVVQENGDE 930
Query: 240 AEKAISVHSTPEGCSSACKMILEIMHKE----AKDTKTA-DEVPLKILAHNNFVGRLIGK 294
A + G C +I+ KE AK+ A V +++ + +IG+
Sbjct: 931 AGEGREAKDCDPGSPRRCDIIIISGRKEKCEAAKEALEALVPVTIEVEVPFDLHRYVIGQ 990
Query: 295 EGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVRE--AYE 352
+G ++K+ + E I + + + I + G N RA+ ++++V+E A +
Sbjct: 991 KGSGIRKMMDEFEVNIHVPAPE-----LQSDIIAITGLAANLDRAKAGLLERVKELQAEQ 1045
Query: 353 NDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSSFMQAPEQEMVQVFI 412
D A S + SVT Y
Sbjct: 1046 EDRALRSFKL--------------------------SVTVDPKYHP-------------- 1065
Query: 413 PAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITG---PPEAQFKAQGR 469
IIG+KG I Q+ +I+ + + + ITG EA A R
Sbjct: 1066 ------KIIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAILR 1119
Query: 470 IYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTP 529
I G+L++ E+V L+ + R+IG GK + ++ + ++ P+ P
Sbjct: 1120 IVGELEQM----VSEDVPLDHRVHA------RIIGARGKAIRKIMDEFKVDIRFPQSGAP 1169
Query: 530 DEN 532
D N
Sbjct: 1170 DPN 1172
Score = 33.5 bits (75), Expect = 0.55
Identities = 24/106 (22%), Positives = 48/106 (45%), Gaps = 14/106 (13%)
Query: 454 VIITGPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNEL 513
++++G +A KA+ I +L + + + +P VIGK G+ + +L
Sbjct: 127 IMVSGKLDAVMKARKDIVARL----------QTQASATVAIPKEHHRFVIGKNGEKLQDL 176
Query: 514 QNLTAAEVVVPRDQTPDENDQVIVKIIGHFYASQMAQRKIRDILAQ 559
+ TA ++ +PR P +KI G + A+ ++ I A+
Sbjct: 177 ELKTATKIQIPRPDDPSNQ----IKITGTKEGIEKARHEVLLISAE 218
Score = 30.8 bits (68), Expect = 3.5
Identities = 29/156 (18%), Positives = 68/156 (43%), Gaps = 5/156 (3%)
Query: 408 VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQ 467
++V +P +IG+KG I+++ +I + PE ++ ITG +A+
Sbjct: 975 IEVEVPFDLHRYVIGQKGSGIRKMMDEFEVNIHVPAPELQSD---IIAITGLAANLDRAK 1031
Query: 468 GRIYGKLKEENFFGPKEEVK-LETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRD 526
+ ++KE ++ + + V ++IG+ G + +++ + P D
Sbjct: 1032 AGLLERVKELQAEQEDRALRSFKLSVTVDPKYHPKIIGRKGAVITQIRLEHDVNIQFP-D 1090
Query: 527 QTPDENDQVIVKIIGHFYASQMAQRKIRDILAQVKQ 562
+ Q + I G+ ++ A+ I I+ +++Q
Sbjct: 1091 KDDGNQPQDQITITGYEKNTEAARDAILRIVGELEQ 1126
>gi|42716280 high density lipoprotein binding protein [Homo sapiens]
Length = 1268
Score = 60.1 bits (144), Expect = 5e-09
Identities = 83/359 (23%), Positives = 142/359 (39%), Gaps = 77/359 (21%)
Query: 200 LLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGCSSACKM 259
L++ ++ IIG++G IR I + I ++ + A ++ I P+ C
Sbjct: 512 LIIEQRFHRTIIGQKGERIREIRDKFPEVI-INFPDPAQKSD--IVQLRGPKNEVEKCTK 568
Query: 260 ILEIMHKEAKDTKTADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLT 319
++ M + + + VP+ H N +IGK G N+KK+ +++ TKI DL
Sbjct: 569 YMQKMVADLVENSYSISVPIFKQFHKN----IIGKGGANIKKIREESNTKI------DLP 618
Query: 320 LYNP-ERTITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPA 378
N TI + G NC A I +S+Q L N+A
Sbjct: 619 AENSNSETIIITGKRANCEAARSRI--------------LSIQKDL---ANIAE------ 655
Query: 379 SSSAVPPPPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASAS 438
V+V IPA+ ++IG KG+ I+ +
Sbjct: 656 -----------------------------VEVSIPAKLHNSLIGTKGRLIRSIMEECGGV 686
Query: 439 IKIAPPETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASA 498
P E S V+I GP KA+ ++ +E K+ IR
Sbjct: 687 HIHFPVEGSGSDT--VVIRGPSSDVEKAKKQLLHLAEE------KQTKSFTVDIRAKPEY 738
Query: 499 AGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQVIVKIIGHFYASQMAQRKIRDIL 557
+IGKGG + ++++ T A V+ P ++ DQ ++ IIG A + AQ+++ ++
Sbjct: 739 HKFLIGKGGGKIRKVRDSTGARVIFP---AAEDKDQDLITIIGKEDAVREAQKELEALI 794
Score = 58.2 bits (139), Expect = 2e-08
Identities = 87/394 (22%), Positives = 162/394 (41%), Gaps = 51/394 (12%)
Query: 193 QVDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEG 252
Q + +P ++ +IGK G ++++ +T +KI + R ++ I + T EG
Sbjct: 148 QTQASATVAIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDD---PSNQIKITGTKEG 204
Query: 253 CSSACKMILEIMHKEAKDTKTADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITI 312
A +L I A+ K A E ++ F + G R + ++ Q+T T+I I
Sbjct: 205 IEKARHEVLLI---SAEQDKRAVE---RLEVEKAFHPFIAGPYNRLVGEIMQETGTRINI 258
Query: 313 SSLQDLTLYNPERT-ITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQ------SHLI 365
+ RT I G E +A I KK+ E + ++++ ++I
Sbjct: 259 PP------PSVNRTEIVFTGEKEQLAQAVARI-KKIYEEKKKKTTTIAVEVKKSQHKYVI 311
Query: 366 -PGLNLAAVGLFPASSSAVPPPPSSVT------------GAAPYSSFMQAPEQEMVQVFI 412
P N L S PP S++ G A + +A + V
Sbjct: 312 GPKGNSLQEILERTGVSVEIPPSDSISETVILRGEPEKLGQALTEVYAKANSFTVSSVAA 371
Query: 413 PAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIYG 472
P+ IIGKKGQ++ ++++ + I E D + + GP E AQ +I G
Sbjct: 372 PSWLHRFIIGKKGQNLAKITQ-QMPKVHIEFTEGEDK----ITLEGPTEDVNVAQEQIEG 426
Query: 473 KLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDEN 532
+K+ + V+ I + +IGK G +N +++ V +P PD
Sbjct: 427 MVKD--LINRMDYVE----INIDHKFHRHLIGKSGANINRIKDQYKVSVRIP----PDSE 476
Query: 533 DQVIVKIIGHFYASQMAQRKIRDILAQVKQQHQK 566
+++I G Q A+R++ ++ ++++ + K
Sbjct: 477 KSNLIRIEGDPQGVQQAKRELLELASRMENERTK 510
Score = 47.0 bits (110), Expect = 5e-05
Identities = 53/218 (24%), Positives = 89/218 (40%), Gaps = 26/218 (11%)
Query: 198 LRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGCSSAC 257
L + V +Y IIG++GA I I + I K++ + I++ + +A
Sbjct: 1055 LSVTVDPKYHPKIIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQITITGYEKNTEAAR 1114
Query: 258 KMILEIMHKEAKDTKTADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITI--SSL 315
IL I+ + + +++VPL H R+IG G+ ++K+ + + I S
Sbjct: 1115 DAILRIVGE--LEQMVSEDVPLDHRVH----ARIIGARGKAIRKIMDEFKVDIRFPQSGA 1168
Query: 316 QDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGL 375
D +TV G EN A I+ E + V + +LQ ++ P
Sbjct: 1169 PD------PNCVTVTGLPENVEEAIDHILNLEEEYLADVVDSEALQVYMKP--------- 1213
Query: 376 FPASSSAVPPPPSSVTGAAPY--SSFMQAPEQEMVQVF 411
PA A P V AP+ SS +AP+ + F
Sbjct: 1214 -PAHEEAKAPSRGFVVRDAPWTASSSEKAPDMSSSEEF 1250
Score = 40.0 bits (92), Expect = 0.006
Identities = 73/363 (20%), Positives = 135/363 (37%), Gaps = 84/363 (23%)
Query: 193 QVDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKID--------VHR-----KENAGA 239
+ + L +P ++ +++G +G+ I+ IT+ +I VH +EN
Sbjct: 871 EAQVTLECAIPQKFHRSVMGPKGSRIQQITRDFSVQIKFPDREENAVHSTEPVVQENGDE 930
Query: 240 AEKAISVHSTPEGCSSACKMILEIMHKE----AKDTKTA-DEVPLKILAHNNFVGRLIGK 294
A + G C +I+ KE AK+ A V +++ + +IG+
Sbjct: 931 AGEGREAKDCDPGSPRRCDIIIISGRKEKCEAAKEALEALVPVTIEVEVPFDLHRYVIGQ 990
Query: 295 EGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVRE--AYE 352
+G ++K+ + E I + + + I + G N RA+ ++++V+E A +
Sbjct: 991 KGSGIRKMMDEFEVNIHVPAPE-----LQSDIIAITGLAANLDRAKAGLLERVKELQAEQ 1045
Query: 353 NDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSSFMQAPEQEMVQVFI 412
D A S + SVT Y
Sbjct: 1046 EDRALRSFKL--------------------------SVTVDPKYHP-------------- 1065
Query: 413 PAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITG---PPEAQFKAQGR 469
IIG+KG I Q+ +I+ + + + ITG EA A R
Sbjct: 1066 ------KIIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAILR 1119
Query: 470 IYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTP 529
I G+L++ E+V L+ + R+IG GK + ++ + ++ P+ P
Sbjct: 1120 IVGELEQM----VSEDVPLDHRVHA------RIIGARGKAIRKIMDEFKVDIRFPQSGAP 1169
Query: 530 DEN 532
D N
Sbjct: 1170 DPN 1172
Score = 33.5 bits (75), Expect = 0.55
Identities = 24/106 (22%), Positives = 48/106 (45%), Gaps = 14/106 (13%)
Query: 454 VIITGPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNEL 513
++++G +A KA+ I +L + + + +P VIGK G+ + +L
Sbjct: 127 IMVSGKLDAVMKARKDIVARL----------QTQASATVAIPKEHHRFVIGKNGEKLQDL 176
Query: 514 QNLTAAEVVVPRDQTPDENDQVIVKIIGHFYASQMAQRKIRDILAQ 559
+ TA ++ +PR P +KI G + A+ ++ I A+
Sbjct: 177 ELKTATKIQIPRPDDPSNQ----IKITGTKEGIEKARHEVLLISAE 218
Score = 30.8 bits (68), Expect = 3.5
Identities = 29/156 (18%), Positives = 68/156 (43%), Gaps = 5/156 (3%)
Query: 408 VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQ 467
++V +P +IG+KG I+++ +I + PE ++ ITG +A+
Sbjct: 975 IEVEVPFDLHRYVIGQKGSGIRKMMDEFEVNIHVPAPELQSD---IIAITGLAANLDRAK 1031
Query: 468 GRIYGKLKEENFFGPKEEVK-LETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRD 526
+ ++KE ++ + + V ++IG+ G + +++ + P D
Sbjct: 1032 AGLLERVKELQAEQEDRALRSFKLSVTVDPKYHPKIIGRKGAVITQIRLEHDVNIQFP-D 1090
Query: 527 QTPDENDQVIVKIIGHFYASQMAQRKIRDILAQVKQ 562
+ Q + I G+ ++ A+ I I+ +++Q
Sbjct: 1091 KDDGNQPQDQITITGYEKNTEAARDAILRIVGELEQ 1126
>gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens]
Length = 492
Score = 59.3 bits (142), Expect = 9e-09
Identities = 56/216 (25%), Positives = 96/216 (44%), Gaps = 21/216 (9%)
Query: 198 LRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKEN--AGAAEKAISVHSTPEGCSS 255
L++L+P+ G+IIGK G TI + K+T + I + + ++ G E+ V T E ++
Sbjct: 35 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNA 94
Query: 256 ACKMILEIMHKEAKDTKTADEV----------------PLKILAHNNFVGRLIGKEGRNL 299
I E + +E T EV K++ N+ G +IGK G +
Sbjct: 95 VHSFIAEKV-REIPQAMTKPEVVNILQPQTTMNPDRAKQAKLIVPNSTAGLIIGKGGATV 153
Query: 300 KKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVRE-AYENDVAAM 358
K V + + + +S + + ER +TV G E +A I++KV+E + +
Sbjct: 154 KAVMEQSGAWVQLSQKPE-GINLQERVVTVSGEPEQVHKAVSAIVQKVQEDPQSSSCLNI 212
Query: 359 SLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAA 394
S + P N G AS + V P ++ + AA
Sbjct: 213 SYANVAGPVANSNPTGSPYASPADVLPAAAAASAAA 248
Score = 57.4 bits (137), Expect = 4e-08
Identities = 52/217 (23%), Positives = 91/217 (41%), Gaps = 32/217 (14%)
Query: 262 EIMHKEAKDTKTADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLY 321
E++ + +T E LK+L + G +IGK G+ + +++++T I +S +D
Sbjct: 18 EVVCTKRSNTGEEGEYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPG 77
Query: 322 NPERTITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSS 381
ER V+G E I +KVRE IP
Sbjct: 78 TTERVCLVQGTAEALNAVHSFIAEKVRE---------------IP--------------Q 108
Query: 382 AVPPPPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKI 441
A+ P V + M + ++ +P G IIGK G +K + + A +++
Sbjct: 109 AMTKP--EVVNILQPQTTMNPDRAKQAKLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQL 166
Query: 442 A-PPETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEE 477
+ PE + + R+V ++G PE KA I K++E+
Sbjct: 167 SQKPEGINLQERVVTVSGEPEQVHKAVSAIVQKVQED 203
Score = 55.8 bits (133), Expect = 1e-07
Identities = 47/174 (27%), Positives = 79/174 (45%), Gaps = 19/174 (10%)
Query: 408 VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPET--PDSKVRMVIITGPPEAQFK 465
++V IP+ A G+IIGK GQ I QL + A+IK++ + P + R+ ++ G EA
Sbjct: 35 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNA 94
Query: 466 AQGRIYGKLKEENFFGPKEEV--------------KLETHIRVPASAAGRVIGKGGKTVN 511
I K++E K EV + + VP S AG +IGKGG TV
Sbjct: 95 VHSFIAEKVREIPQAMTKPEVVNILQPQTTMNPDRAKQAKLIVPNSTAGLIIGKGGATVK 154
Query: 512 ELQNLTAAEVVVPRDQTPDENDQVIVKIIGHFYASQMAQRKIRDILAQVKQQHQ 565
+ + A V + + + +V + G + + + I+ +V++ Q
Sbjct: 155 AVMEQSGAWVQLSQKPEGINLQERVVTVSGE---PEQVHKAVSAIVQKVQEDPQ 205
Score = 53.5 bits (127), Expect = 5e-07
Identities = 75/350 (21%), Positives = 121/350 (34%), Gaps = 94/350 (26%)
Query: 199 RLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRK-ENAGAAEKAISVHSTPEGCSSAC 257
+L+VP G IIGK GAT++ + +Q+ + + + +K E E+ ++V PE A
Sbjct: 134 KLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKAV 193
Query: 258 KMILEIMHKEAKDTKT-------------------------ADEVPLKILAHNNFVGRLI 292
I++ + ++ + + AD +P A L+
Sbjct: 194 SAIVQKVQEDPQSSSCLNISYANVAGPVANSNPTGSPYASPADVLPAAAAASAAAASGLL 253
Query: 293 GKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYE 352
G G L V S L + T+ G N
Sbjct: 254 GPAG--LAGVGAFPAALPAFSGTDLLAISTALNTLASYGYNTNSLGLGL----------- 300
Query: 353 NDVAAMSLQSHLIPGLNLAAV-------------GLFPASSSAVPPPP------------ 387
N AA + + + G N AA G PA +A PPPP
Sbjct: 301 NSAAASGVLAAVAAGANPAAAAAANLLASYAGEAGAGPAGGAAPPPPPPPGALGSFALAA 360
Query: 388 ----------------------SSVTGAAPYSSFMQAPE------QEMVQVFIPAQAVGA 419
++ A F+ A + +E+V++ +P VGA
Sbjct: 361 AANGYLGAGAGGGAGGGGGPLVAAAAAAGAAGGFLTAEKLAAESAKELVEIAVPENLVGA 420
Query: 420 IIGKKGQHIKQLSRFASASIKIAPPE--TPDSKVRMVIITGPPEAQFKAQ 467
I+GK G+ + + A I+I+ P ++ R V ITG P A AQ
Sbjct: 421 ILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQAAQ 470
Score = 40.0 bits (92), Expect = 0.006
Identities = 25/68 (36%), Positives = 32/68 (47%), Gaps = 2/68 (2%)
Query: 458 GPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLT 517
GP A A G G L E E K I VP + G ++GKGGKT+ E Q LT
Sbjct: 379 GPLVAAAAAAGAAGGFLTAEKLAA--ESAKELVEIAVPENLVGAILGKGGKTLVEYQELT 436
Query: 518 AAEVVVPR 525
A + + +
Sbjct: 437 GARIQISK 444
Score = 38.1 bits (87), Expect = 0.022
Identities = 25/84 (29%), Positives = 40/84 (47%), Gaps = 14/84 (16%)
Query: 444 PETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVI 503
PE PDS+ R + PPE + EE + + +P+ AAG +I
Sbjct: 3 PEAPDSRKRP--LETPPEVVCTKRSNT------------GEEGEYFLKVLIPSYAAGSII 48
Query: 504 GKGGKTVNELQNLTAAEVVVPRDQ 527
GKGG+T+ +LQ T A + + + +
Sbjct: 49 GKGGQTIVQLQKETGATIKLSKSK 72
Score = 38.1 bits (87), Expect = 0.022
Identities = 27/105 (25%), Positives = 45/105 (42%), Gaps = 10/105 (9%)
Query: 166 GRRGGFGSRGQPRQGSPVAAGAPA--------KQQQVDIPLRLLVPTQYVGAIIGKEGAT 217
G GG G G P + AAGA + + + VP VGAI+GK G T
Sbjct: 369 GAGGGAGGGGGPLVAAAAAAGAAGGFLTAEKLAAESAKELVEIAVPENLVGAILGKGGKT 428
Query: 218 IRNITKQTQSKIDVHRKEN--AGAAEKAISVHSTPEGCSSACKMI 260
+ + T ++I + +K G + +++ +P +A +I
Sbjct: 429 LVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQAAQYLI 473
Score = 33.5 bits (75), Expect = 0.55
Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 2/83 (2%)
Query: 279 LKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCR 338
++I N VG ++GK G+ L + ++ T +I IS + R +T+ G+
Sbjct: 409 VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQA 468
Query: 339 AEQEIMKKVREAYENDVAAMSLQ 361
A+ I ++V YE V A + Q
Sbjct: 469 AQYLISQRV--TYEQGVRASNPQ 489
>gi|145312259 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 58.5 bits (140), Expect = 2e-08
Identities = 40/165 (24%), Positives = 78/165 (47%), Gaps = 19/165 (11%)
Query: 386 PPSSVTGAAPYSSFMQAPEQEM---------VQVFIPAQAVGAIIGKKGQHIKQLSRFAS 436
P S+ Y + ++ E+ + +++ +P +AV IIG++G +IKQL +
Sbjct: 24 PASATVAYILYRRYRESREERLTFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTG 83
Query: 437 ASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPA 496
A I + + D R+++I+G P KA+ I+ L E + + VP
Sbjct: 84 ARIDVDTEDVGDE--RVLLISGFPVQVCKAKAAIHQIL--------TENTPVSEQLSVPQ 133
Query: 497 SAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQVIVKIIG 541
+ GR+IG+GG+T+ + + A++ ++ ++KI G
Sbjct: 134 RSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISG 178
Score = 57.4 bits (137), Expect = 4e-08
Identities = 45/158 (28%), Positives = 78/158 (49%), Gaps = 10/158 (6%)
Query: 195 DIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGCS 254
DI + + VP + V IIG++GA I+ + KQT ++IDV E+ G E+ + + P
Sbjct: 52 DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVD-TEDVG-DERVLLISGFP---V 106
Query: 255 SACKMILEIMHKEAKDTKTADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISS 314
CK I ++T ++++ + VGR+IG+ G ++ + + + KIT
Sbjct: 107 QVCKAKAAIHQILTENTPVSEQLSVP----QRSVGRIIGRGGETIRSICKASGAKITCDK 162
Query: 315 LQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYE 352
+ TL R I + G + A+ I++KV E E
Sbjct: 163 ESEGTLL-LSRLIKISGTQKEVAAAKHLILEKVSEDEE 199
Score = 32.7 bits (73), Expect = 0.93
Identities = 21/100 (21%), Positives = 48/100 (48%), Gaps = 8/100 (8%)
Query: 254 SSACKMILEIMHKEAKDTKTA----DEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETK 309
S+ IL ++E+++ + D++ +++ V +IG++G N+K++ + T +
Sbjct: 26 SATVAYILYRRYRESREERLTFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGAR 85
Query: 310 ITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVRE 349
I + D ER + + G C+A+ I + + E
Sbjct: 86 IDV----DTEDVGDERVLLISGFPVQVCKAKAAIHQILTE 121
>gi|145312270 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 58.5 bits (140), Expect = 2e-08
Identities = 40/165 (24%), Positives = 78/165 (47%), Gaps = 19/165 (11%)
Query: 386 PPSSVTGAAPYSSFMQAPEQEM---------VQVFIPAQAVGAIIGKKGQHIKQLSRFAS 436
P S+ Y + ++ E+ + +++ +P +AV IIG++G +IKQL +
Sbjct: 24 PASATVAYILYRRYRESREERLTFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTG 83
Query: 437 ASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPA 496
A I + + D R+++I+G P KA+ I+ L E + + VP
Sbjct: 84 ARIDVDTEDVGDE--RVLLISGFPVQVCKAKAAIHQIL--------TENTPVSEQLSVPQ 133
Query: 497 SAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQVIVKIIG 541
+ GR+IG+GG+T+ + + A++ ++ ++KI G
Sbjct: 134 RSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISG 178
Score = 57.4 bits (137), Expect = 4e-08
Identities = 45/158 (28%), Positives = 78/158 (49%), Gaps = 10/158 (6%)
Query: 195 DIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGCS 254
DI + + VP + V IIG++GA I+ + KQT ++IDV E+ G E+ + + P
Sbjct: 52 DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVD-TEDVG-DERVLLISGFP---V 106
Query: 255 SACKMILEIMHKEAKDTKTADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISS 314
CK I ++T ++++ + VGR+IG+ G ++ + + + KIT
Sbjct: 107 QVCKAKAAIHQILTENTPVSEQLSVP----QRSVGRIIGRGGETIRSICKASGAKITCDK 162
Query: 315 LQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYE 352
+ TL R I + G + A+ I++KV E E
Sbjct: 163 ESEGTLL-LSRLIKISGTQKEVAAAKHLILEKVSEDEE 199
Score = 32.7 bits (73), Expect = 0.93
Identities = 21/100 (21%), Positives = 48/100 (48%), Gaps = 8/100 (8%)
Query: 254 SSACKMILEIMHKEAKDTKTA----DEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETK 309
S+ IL ++E+++ + D++ +++ V +IG++G N+K++ + T +
Sbjct: 26 SATVAYILYRRYRESREERLTFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGAR 85
Query: 310 ITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVRE 349
I + D ER + + G C+A+ I + + E
Sbjct: 86 IDV----DTEDVGDERVLLISGFPVQVCKAKAAIHQILTE 121
>gi|145312256 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 58.5 bits (140), Expect = 2e-08
Identities = 40/165 (24%), Positives = 78/165 (47%), Gaps = 19/165 (11%)
Query: 386 PPSSVTGAAPYSSFMQAPEQEM---------VQVFIPAQAVGAIIGKKGQHIKQLSRFAS 436
P S+ Y + ++ E+ + +++ +P +AV IIG++G +IKQL +
Sbjct: 24 PASATVAYILYRRYRESREERLTFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTG 83
Query: 437 ASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPA 496
A I + + D R+++I+G P KA+ I+ L E + + VP
Sbjct: 84 ARIDVDTEDVGDE--RVLLISGFPVQVCKAKAAIHQIL--------TENTPVSEQLSVPQ 133
Query: 497 SAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQVIVKIIG 541
+ GR+IG+GG+T+ + + A++ ++ ++KI G
Sbjct: 134 RSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISG 178
Score = 57.4 bits (137), Expect = 4e-08
Identities = 45/158 (28%), Positives = 78/158 (49%), Gaps = 10/158 (6%)
Query: 195 DIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGCS 254
DI + + VP + V IIG++GA I+ + KQT ++IDV E+ G E+ + + P
Sbjct: 52 DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVD-TEDVG-DERVLLISGFP---V 106
Query: 255 SACKMILEIMHKEAKDTKTADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISS 314
CK I ++T ++++ + VGR+IG+ G ++ + + + KIT
Sbjct: 107 QVCKAKAAIHQILTENTPVSEQLSVP----QRSVGRIIGRGGETIRSICKASGAKITCDK 162
Query: 315 LQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYE 352
+ TL R I + G + A+ I++KV E E
Sbjct: 163 ESEGTLL-LSRLIKISGTQKEVAAAKHLILEKVSEDEE 199
Score = 32.7 bits (73), Expect = 0.93
Identities = 21/100 (21%), Positives = 48/100 (48%), Gaps = 8/100 (8%)
Query: 254 SSACKMILEIMHKEAKDTKTA----DEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETK 309
S+ IL ++E+++ + D++ +++ V +IG++G N+K++ + T +
Sbjct: 26 SATVAYILYRRYRESREERLTFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGAR 85
Query: 310 ITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVRE 349
I + D ER + + G C+A+ I + + E
Sbjct: 86 IDV----DTEDVGDERVLLISGFPVQVCKAKAAIHQILTE 121
>gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a
[Homo sapiens]
Length = 464
Score = 58.2 bits (139), Expect = 2e-08
Identities = 52/194 (26%), Positives = 84/194 (43%), Gaps = 28/194 (14%)
Query: 269 KDTKTADE-VPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTI 327
K ++ DE V L+IL + G +IGK G+N+K + D +++ PER +
Sbjct: 34 KRSRNTDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSS-----GPERIL 88
Query: 328 TVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPP 387
++ IE EI+KK+ E GL L + P ++S +P
Sbjct: 89 SISADIETI----GEILKKIIPTLEE-------------GLQLPS----PTATSQLPLES 127
Query: 388 SSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETP 447
+V Y + + +++ I G IIG KG IK+L +IK+ P
Sbjct: 128 DAVE-CLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCP 186
Query: 448 DSKVRMVIITGPPE 461
S R+V+I G P+
Sbjct: 187 HSTDRVVLIGGKPD 200
Score = 46.6 bits (109), Expect = 6e-05
Identities = 40/212 (18%), Positives = 86/212 (40%), Gaps = 30/212 (14%)
Query: 163 PENGRRGGFGSRGQPRQGSPVAAGAPAKQQQVDIPLRLLVPTQYVGAIIGKEGATIRNIT 222
P G FG R A ++ + LR+L+ ++ GA+IGK G I+ +
Sbjct: 11 PNTETNGEFGKRPAEDMEEEQAFKRSRNTDEM-VELRILLQSKNAGAVIGKGGKNIKALR 69
Query: 223 KQTQSKIDVHRKENAGAAEKAISVHSTPEGCSSACKMILEIMHK--EAKDTKTADEVP-- 278
+ + V ++ E+ +S+ + E K I+ + + + ++P
Sbjct: 70 TDYNASVSV---PDSSGPERILSISADIETIGEILKKIIPTLEEGLQLPSPTATSQLPLE 126
Query: 279 --------------------LKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDL 318
L++L H + G +IG +G +K++ ++T+T TI Q+
Sbjct: 127 SDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQT--TIKLFQEC 184
Query: 319 TLYNPERTITVKGAIENCCRAEQEIMKKVREA 350
++ +R + + G + + I+ + E+
Sbjct: 185 CPHSTDRVVLIGGKPDRVVECIKIILDLISES 216
Score = 45.1 bits (105), Expect = 2e-04
Identities = 28/68 (41%), Positives = 38/68 (55%), Gaps = 1/68 (1%)
Query: 409 QVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQG 468
QV IP G+IIGK GQ IKQ+ + ASIKI P S+ R++ ITG + AQ
Sbjct: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEP-LEGSEDRIITITGTQDQIQNAQY 449
Query: 469 RIYGKLKE 476
+ +K+
Sbjct: 450 LLQNSVKQ 457
Score = 35.4 bits (80), Expect = 0.14
Identities = 18/72 (25%), Positives = 40/72 (55%), Gaps = 2/72 (2%)
Query: 488 LETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQVIVKIIGHFYASQ 547
+ T + +P AG +IGKGG+ + ++++ + A + + D+ + ++ I+ I G Q
Sbjct: 388 ITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI--DEPLEGSEDRIITITGTQDQIQ 445
Query: 548 MAQRKIRDILAQ 559
AQ +++ + Q
Sbjct: 446 NAQYLLQNSVKQ 457
Score = 32.3 bits (72), Expect = 1.2
Identities = 17/43 (39%), Positives = 23/43 (53%)
Query: 488 LETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPD 530
+E I + + AG VIGKGGK + L+ A V VP P+
Sbjct: 43 VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPE 85
Score = 30.8 bits (68), Expect = 3.5
Identities = 29/106 (27%), Positives = 49/106 (46%), Gaps = 10/106 (9%)
Query: 152 SYIPDE-QIAQGPENGRRGGFGSRGQPRQGSPVAAGAPAKQQQVDIPLRLLVPTQYVGAI 210
++ P E Q+A P+ G + G +GS G P QV IP L G+I
Sbjct: 351 TWSPSEWQMAYEPQGGSGYDYSYAGG--RGSYGDLGGPIITTQVTIPKDL------AGSI 402
Query: 211 IGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGCSSA 256
IGK G I+ I ++ + I + + G+ ++ I++ T + +A
Sbjct: 403 IGKGGQRIKQIRHESGASIKID-EPLEGSEDRIITITGTQDQIQNA 447
>gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b
[Homo sapiens]
Length = 463
Score = 58.2 bits (139), Expect = 2e-08
Identities = 52/194 (26%), Positives = 84/194 (43%), Gaps = 28/194 (14%)
Query: 269 KDTKTADE-VPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTI 327
K ++ DE V L+IL + G +IGK G+N+K + D +++ PER +
Sbjct: 34 KRSRNTDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSS-----GPERIL 88
Query: 328 TVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPP 387
++ IE EI+KK+ E GL L + P ++S +P
Sbjct: 89 SISADIETI----GEILKKIIPTLEE-------------GLQLPS----PTATSQLPLES 127
Query: 388 SSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETP 447
+V Y + + +++ I G IIG KG IK+L +IK+ P
Sbjct: 128 DAVE-CLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCP 186
Query: 448 DSKVRMVIITGPPE 461
S R+V+I G P+
Sbjct: 187 HSTDRVVLIGGKPD 200
Score = 46.6 bits (109), Expect = 6e-05
Identities = 40/212 (18%), Positives = 86/212 (40%), Gaps = 30/212 (14%)
Query: 163 PENGRRGGFGSRGQPRQGSPVAAGAPAKQQQVDIPLRLLVPTQYVGAIIGKEGATIRNIT 222
P G FG R A ++ + LR+L+ ++ GA+IGK G I+ +
Sbjct: 11 PNTETNGEFGKRPAEDMEEEQAFKRSRNTDEM-VELRILLQSKNAGAVIGKGGKNIKALR 69
Query: 223 KQTQSKIDVHRKENAGAAEKAISVHSTPEGCSSACKMILEIMHK--EAKDTKTADEVP-- 278
+ + V ++ E+ +S+ + E K I+ + + + ++P
Sbjct: 70 TDYNASVSV---PDSSGPERILSISADIETIGEILKKIIPTLEEGLQLPSPTATSQLPLE 126
Query: 279 --------------------LKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDL 318
L++L H + G +IG +G +K++ ++T+T TI Q+
Sbjct: 127 SDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQT--TIKLFQEC 184
Query: 319 TLYNPERTITVKGAIENCCRAEQEIMKKVREA 350
++ +R + + G + + I+ + E+
Sbjct: 185 CPHSTDRVVLIGGKPDRVVECIKIILDLISES 216
Score = 45.1 bits (105), Expect = 2e-04
Identities = 28/68 (41%), Positives = 38/68 (55%), Gaps = 1/68 (1%)
Query: 409 QVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQG 468
QV IP G+IIGK GQ IKQ+ + ASIKI P S+ R++ ITG + AQ
Sbjct: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEP-LEGSEDRIITITGTQDQIQNAQY 449
Query: 469 RIYGKLKE 476
+ +K+
Sbjct: 450 LLQNSVKQ 457
Score = 35.4 bits (80), Expect = 0.14
Identities = 18/72 (25%), Positives = 40/72 (55%), Gaps = 2/72 (2%)
Query: 488 LETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQVIVKIIGHFYASQ 547
+ T + +P AG +IGKGG+ + ++++ + A + + D+ + ++ I+ I G Q
Sbjct: 388 ITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI--DEPLEGSEDRIITITGTQDQIQ 445
Query: 548 MAQRKIRDILAQ 559
AQ +++ + Q
Sbjct: 446 NAQYLLQNSVKQ 457
Score = 32.3 bits (72), Expect = 1.2
Identities = 17/43 (39%), Positives = 23/43 (53%)
Query: 488 LETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPD 530
+E I + + AG VIGKGGK + L+ A V VP P+
Sbjct: 43 VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPE 85
Score = 30.8 bits (68), Expect = 3.5
Identities = 29/106 (27%), Positives = 49/106 (46%), Gaps = 10/106 (9%)
Query: 152 SYIPDE-QIAQGPENGRRGGFGSRGQPRQGSPVAAGAPAKQQQVDIPLRLLVPTQYVGAI 210
++ P E Q+A P+ G + G +GS G P QV IP L G+I
Sbjct: 351 TWSPSEWQMAYEPQGGSGYDYSYAGG--RGSYGDLGGPIITTQVTIPKDL------AGSI 402
Query: 211 IGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGCSSA 256
IGK G I+ I ++ + I + + G+ ++ I++ T + +A
Sbjct: 403 IGKGGQRIKQIRHESGASIKID-EPLEGSEDRIITITGTQDQIQNA 447
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.364
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,868,231
Number of Sequences: 37866
Number of extensions: 1016115
Number of successful extensions: 4194
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 80
Number of HSP's successfully gapped in prelim test: 137
Number of HSP's that attempted gapping in prelim test: 3564
Number of HSP's gapped (non-prelim): 569
length of query: 577
length of database: 18,247,518
effective HSP length: 108
effective length of query: 469
effective length of database: 14,157,990
effective search space: 6640097310
effective search space used: 6640097310
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.