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Search of human proteins with 55953102
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|55953102 tubby like protein 4 isoform 2 [Homo sapiens]
(678 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|55953102 tubby like protein 4 isoform 2 [Homo sapiens] 1390 0.0
gi|55953100 tubby like protein 4 isoform 1 [Homo sapiens] 1374 0.0
gi|56243599 WD repeat domain 35 isoform 2 [Homo sapiens] 144 3e-34
gi|55743161 WD repeat domain 35 isoform 1 [Homo sapiens] 144 3e-34
gi|16554629 WD repeat domain 5 [Homo sapiens] 50 5e-06
gi|16554627 WD repeat domain 5 [Homo sapiens] 50 5e-06
gi|23199987 WD repeat domain 5B [Homo sapiens] 50 9e-06
gi|22907052 actin related protein 2/3 complex subunit 1A [Homo s... 42 0.002
gi|37620163 ANKHD1-EIF4EBP3 protein [Homo sapiens] 40 0.009
gi|19913367 transducin beta-like 1Y [Homo sapiens] 40 0.009
gi|19913365 transducin beta-like 1Y [Homo sapiens] 40 0.009
gi|15150805 transducin beta-like 1Y [Homo sapiens] 40 0.009
gi|210032390 SEC13 protein isoform 2 [Homo sapiens] 39 0.016
gi|34335134 SEC13 protein isoform 1 [Homo sapiens] 39 0.016
gi|109948304 smu-1 suppressor of mec-8 and unc-52 homolog [Homo ... 38 0.035
gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo s... 37 0.046
gi|213021190 transducin beta-like 1X isoform b [Homo sapiens] 37 0.078
gi|213021188 transducin beta-like 1X isoform b [Homo sapiens] 37 0.078
gi|213021186 transducin beta-like 1X isoform a [Homo sapiens] 37 0.078
gi|5032159 transducin beta-like 1X isoform a [Homo sapiens] 37 0.078
gi|4757988 WD repeat domain 39 [Homo sapiens] 35 0.17
gi|24430146 nucleoporin 153kDa [Homo sapiens] 35 0.30
gi|238859545 tubby like protein 2 [Homo sapiens] 34 0.39
gi|51242945 striatin, calmodulin binding protein [Homo sapiens] 34 0.39
gi|32189425 WD repeat domain 69 [Homo sapiens] 34 0.39
gi|209969680 Fzr1 protein isoform 1 [Homo sapiens] 34 0.51
gi|209969678 Fzr1 protein isoform 3 [Homo sapiens] 34 0.51
gi|33620742 Fzr1 protein isoform 2 [Homo sapiens] 34 0.51
gi|16418439 WD repeat and FYVE domain containing 2 [Homo sapiens] 34 0.51
gi|18254460 splA/ryanodine receptor domain and SOCS box containi... 33 0.66
>gi|55953102 tubby like protein 4 isoform 2 [Homo sapiens]
Length = 678
Score = 1390 bits (3598), Expect = 0.0
Identities = 678/678 (100%), Positives = 678/678 (100%)
Query: 1 MYAAVEHGPVLCSDSNILCLSWKGRVPKSEKEKPVCRRRYYEEGWLATGNGRGVVGVTFT 60
MYAAVEHGPVLCSDSNILCLSWKGRVPKSEKEKPVCRRRYYEEGWLATGNGRGVVGVTFT
Sbjct: 1 MYAAVEHGPVLCSDSNILCLSWKGRVPKSEKEKPVCRRRYYEEGWLATGNGRGVVGVTFT 60
Query: 61 SSHCRRDRSTPQRINFNLRGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEGRWSVEL 120
SSHCRRDRSTPQRINFNLRGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEGRWSVEL
Sbjct: 61 SSHCRRDRSTPQRINFNLRGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEGRWSVEL 120
Query: 121 VNDRGAQVSDFTWSHDGTQALISYRDGFVLVGSVSGQRHWSSEINLESQITCGIWTPDDQ 180
VNDRGAQVSDFTWSHDGTQALISYRDGFVLVGSVSGQRHWSSEINLESQITCGIWTPDDQ
Sbjct: 121 VNDRGAQVSDFTWSHDGTQALISYRDGFVLVGSVSGQRHWSSEINLESQITCGIWTPDDQ 180
Query: 181 QVLFGTADGQVIVMDCHGRMLAHVLLHESDGVLGMSWNYPIFLVEDSSESDTDSDDYAPP 240
QVLFGTADGQVIVMDCHGRMLAHVLLHESDGVLGMSWNYPIFLVEDSSESDTDSDDYAPP
Sbjct: 181 QVLFGTADGQVIVMDCHGRMLAHVLLHESDGVLGMSWNYPIFLVEDSSESDTDSDDYAPP 240
Query: 241 QDGPAAYPIPVQNIKPLLTVSFTSGDISLMNNYDDLSPTVIRSGLKEVVAQWCTQGDLLA 300
QDGPAAYPIPVQNIKPLLTVSFTSGDISLMNNYDDLSPTVIRSGLKEVVAQWCTQGDLLA
Sbjct: 241 QDGPAAYPIPVQNIKPLLTVSFTSGDISLMNNYDDLSPTVIRSGLKEVVAQWCTQGDLLA 300
Query: 301 VAGMERQTQLGELPNGPLLKSAMVKFYNVRGEHIFTLDTLVQRPIISICWGHRDSRLLMA 360
VAGMERQTQLGELPNGPLLKSAMVKFYNVRGEHIFTLDTLVQRPIISICWGHRDSRLLMA
Sbjct: 301 VAGMERQTQLGELPNGPLLKSAMVKFYNVRGEHIFTLDTLVQRPIISICWGHRDSRLLMA 360
Query: 361 SGPALYVVRVEHRVSSLQLLCQQAIASTLREDKDVSKLTLPPRLCSYLSTAFIPTIKPPI 420
SGPALYVVRVEHRVSSLQLLCQQAIASTLREDKDVSKLTLPPRLCSYLSTAFIPTIKPPI
Sbjct: 361 SGPALYVVRVEHRVSSLQLLCQQAIASTLREDKDVSKLTLPPRLCSYLSTAFIPTIKPPI 420
Query: 421 PDPNNMRDFVSYPSAGNERLHCTMKRTEDDPEVGGPCYTLYLEYLGGLVPILKGRRISKL 480
PDPNNMRDFVSYPSAGNERLHCTMKRTEDDPEVGGPCYTLYLEYLGGLVPILKGRRISKL
Sbjct: 421 PDPNNMRDFVSYPSAGNERLHCTMKRTEDDPEVGGPCYTLYLEYLGGLVPILKGRRISKL 480
Query: 481 RPEFVIMDPRTDSKPDEIYGNSLISTVIDSCNCSDSSDIELSDDWAAKKSPKISRASKSP 540
RPEFVIMDPRTDSKPDEIYGNSLISTVIDSCNCSDSSDIELSDDWAAKKSPKISRASKSP
Sbjct: 481 RPEFVIMDPRTDSKPDEIYGNSLISTVIDSCNCSDSSDIELSDDWAAKKSPKISRASKSP 540
Query: 541 KLPRISIEARKSPKLPRAAQELSRSPRLPLRKPSVGSPSLTRREFPFEDITQHNYLAQVT 600
KLPRISIEARKSPKLPRAAQELSRSPRLPLRKPSVGSPSLTRREFPFEDITQHNYLAQVT
Sbjct: 541 KLPRISIEARKSPKLPRAAQELSRSPRLPLRKPSVGSPSLTRREFPFEDITQHNYLAQVT 600
Query: 601 SNIWGTKFKIVGLAAFLPTNLGAVIYKTSLLHLQPRQMTIYLPEVRKISMDYINLPVFNP 660
SNIWGTKFKIVGLAAFLPTNLGAVIYKTSLLHLQPRQMTIYLPEVRKISMDYINLPVFNP
Sbjct: 601 SNIWGTKFKIVGLAAFLPTNLGAVIYKTSLLHLQPRQMTIYLPEVRKISMDYINLPVFNP 660
Query: 661 NVFSEDEDDLPGDAVWTD 678
NVFSEDEDDLPGDAVWTD
Sbjct: 661 NVFSEDEDDLPGDAVWTD 678
>gi|55953100 tubby like protein 4 isoform 1 [Homo sapiens]
Length = 1543
Score = 1374 bits (3556), Expect = 0.0
Identities = 671/671 (100%), Positives = 671/671 (100%)
Query: 1 MYAAVEHGPVLCSDSNILCLSWKGRVPKSEKEKPVCRRRYYEEGWLATGNGRGVVGVTFT 60
MYAAVEHGPVLCSDSNILCLSWKGRVPKSEKEKPVCRRRYYEEGWLATGNGRGVVGVTFT
Sbjct: 1 MYAAVEHGPVLCSDSNILCLSWKGRVPKSEKEKPVCRRRYYEEGWLATGNGRGVVGVTFT 60
Query: 61 SSHCRRDRSTPQRINFNLRGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEGRWSVEL 120
SSHCRRDRSTPQRINFNLRGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEGRWSVEL
Sbjct: 61 SSHCRRDRSTPQRINFNLRGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEGRWSVEL 120
Query: 121 VNDRGAQVSDFTWSHDGTQALISYRDGFVLVGSVSGQRHWSSEINLESQITCGIWTPDDQ 180
VNDRGAQVSDFTWSHDGTQALISYRDGFVLVGSVSGQRHWSSEINLESQITCGIWTPDDQ
Sbjct: 121 VNDRGAQVSDFTWSHDGTQALISYRDGFVLVGSVSGQRHWSSEINLESQITCGIWTPDDQ 180
Query: 181 QVLFGTADGQVIVMDCHGRMLAHVLLHESDGVLGMSWNYPIFLVEDSSESDTDSDDYAPP 240
QVLFGTADGQVIVMDCHGRMLAHVLLHESDGVLGMSWNYPIFLVEDSSESDTDSDDYAPP
Sbjct: 181 QVLFGTADGQVIVMDCHGRMLAHVLLHESDGVLGMSWNYPIFLVEDSSESDTDSDDYAPP 240
Query: 241 QDGPAAYPIPVQNIKPLLTVSFTSGDISLMNNYDDLSPTVIRSGLKEVVAQWCTQGDLLA 300
QDGPAAYPIPVQNIKPLLTVSFTSGDISLMNNYDDLSPTVIRSGLKEVVAQWCTQGDLLA
Sbjct: 241 QDGPAAYPIPVQNIKPLLTVSFTSGDISLMNNYDDLSPTVIRSGLKEVVAQWCTQGDLLA 300
Query: 301 VAGMERQTQLGELPNGPLLKSAMVKFYNVRGEHIFTLDTLVQRPIISICWGHRDSRLLMA 360
VAGMERQTQLGELPNGPLLKSAMVKFYNVRGEHIFTLDTLVQRPIISICWGHRDSRLLMA
Sbjct: 301 VAGMERQTQLGELPNGPLLKSAMVKFYNVRGEHIFTLDTLVQRPIISICWGHRDSRLLMA 360
Query: 361 SGPALYVVRVEHRVSSLQLLCQQAIASTLREDKDVSKLTLPPRLCSYLSTAFIPTIKPPI 420
SGPALYVVRVEHRVSSLQLLCQQAIASTLREDKDVSKLTLPPRLCSYLSTAFIPTIKPPI
Sbjct: 361 SGPALYVVRVEHRVSSLQLLCQQAIASTLREDKDVSKLTLPPRLCSYLSTAFIPTIKPPI 420
Query: 421 PDPNNMRDFVSYPSAGNERLHCTMKRTEDDPEVGGPCYTLYLEYLGGLVPILKGRRISKL 480
PDPNNMRDFVSYPSAGNERLHCTMKRTEDDPEVGGPCYTLYLEYLGGLVPILKGRRISKL
Sbjct: 421 PDPNNMRDFVSYPSAGNERLHCTMKRTEDDPEVGGPCYTLYLEYLGGLVPILKGRRISKL 480
Query: 481 RPEFVIMDPRTDSKPDEIYGNSLISTVIDSCNCSDSSDIELSDDWAAKKSPKISRASKSP 540
RPEFVIMDPRTDSKPDEIYGNSLISTVIDSCNCSDSSDIELSDDWAAKKSPKISRASKSP
Sbjct: 481 RPEFVIMDPRTDSKPDEIYGNSLISTVIDSCNCSDSSDIELSDDWAAKKSPKISRASKSP 540
Query: 541 KLPRISIEARKSPKLPRAAQELSRSPRLPLRKPSVGSPSLTRREFPFEDITQHNYLAQVT 600
KLPRISIEARKSPKLPRAAQELSRSPRLPLRKPSVGSPSLTRREFPFEDITQHNYLAQVT
Sbjct: 541 KLPRISIEARKSPKLPRAAQELSRSPRLPLRKPSVGSPSLTRREFPFEDITQHNYLAQVT 600
Query: 601 SNIWGTKFKIVGLAAFLPTNLGAVIYKTSLLHLQPRQMTIYLPEVRKISMDYINLPVFNP 660
SNIWGTKFKIVGLAAFLPTNLGAVIYKTSLLHLQPRQMTIYLPEVRKISMDYINLPVFNP
Sbjct: 601 SNIWGTKFKIVGLAAFLPTNLGAVIYKTSLLHLQPRQMTIYLPEVRKISMDYINLPVFNP 660
Query: 661 NVFSEDEDDLP 671
NVFSEDEDDLP
Sbjct: 661 NVFSEDEDDLP 671
>gi|56243599 WD repeat domain 35 isoform 2 [Homo sapiens]
Length = 1170
Score = 144 bits (363), Expect = 3e-34
Identities = 104/364 (28%), Positives = 172/364 (47%), Gaps = 50/364 (13%)
Query: 20 LSWKGRVPKSEKEKPVCRRRYYEEGWLATGNGRGVVGV----TFTSSHCRRDRSTPQRIN 75
LS K +P + K + V + E+G++A G G++ V T T R + P ++
Sbjct: 5 LSKKISIPNNVKLQCVSWNK--EQGFIACGGEDGLLKVLKLETQTDDAKLRGLAAPSNLS 62
Query: 76 FN--LRGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEGRWSVELVNDRG-AQVSDFT 132
N L GH+ V +V WNE YQKL T D +G I VW+ Y+G W E++N+R + V +
Sbjct: 63 MNQTLEGHSGSVQVVTWNEQYQKLTTSDENGLIIVWMLYKGSWIEEMINNRNKSVVRSMS 122
Query: 133 WSHDGTQALISYRDGFVLVGSVSGQRHWSSEINLESQITCGIWTPDDQQVLFGTADGQVI 192
W+ DG + I Y DG V+VGSV G R W ++ Q++ W+ D + +LFG A+G++
Sbjct: 123 WNADGQKICIVYEDGAVIVGSVDGNRIWGKDLK-GIQLSHVTWSADSKVLLFGMANGEIH 181
Query: 193 VMDCHGRMLAHVLLH------ESDGVLGMSWNYPIFLVEDSSESDTDSDDYAPPQDGPAA 246
+ D G + + L + + G+ W + ++ Y P
Sbjct: 182 IYDNQGNFMIKMKLSCLVNVTGAISIAGIHWYH-------------GTEGYVEPD----- 223
Query: 247 YPIPVQNIKPLLTVSFTSGDISLMNNYDDLSPTVIRSGLKEVVAQWCTQGDLLAVAGMER 306
P L V F +G +M + +D +P +I +G+ V QW G +LAVAG ++
Sbjct: 224 --------CPCLAVCFDNGRCQIMRHENDQNPVLIDTGMYVVGIQWNHMGSVLAVAGFQK 275
Query: 307 QTQLGELPNGPLLKSAMVKFYNVRGEHIFTLDTLVQRPIISICWGHRDSRLLMASGPALY 366
+ N +V+FY GEH+ TL + + I ++ W ++ +A +Y
Sbjct: 276 AAMQDKDVN-------IVQFYTPFGEHLGTL-KVPGKEISALSWEGGGLKIALAVDSFIY 327
Query: 367 VVRV 370
+
Sbjct: 328 FANI 331
>gi|55743161 WD repeat domain 35 isoform 1 [Homo sapiens]
Length = 1181
Score = 144 bits (363), Expect = 3e-34
Identities = 104/364 (28%), Positives = 172/364 (47%), Gaps = 50/364 (13%)
Query: 20 LSWKGRVPKSEKEKPVCRRRYYEEGWLATGNGRGVVGV----TFTSSHCRRDRSTPQRIN 75
LS K +P + K + V + E+G++A G G++ V T T R + P ++
Sbjct: 5 LSKKISIPNNVKLQCVSWNK--EQGFIACGGEDGLLKVLKLETQTDDAKLRGLAAPSNLS 62
Query: 76 FN--LRGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEGRWSVELVNDRG-AQVSDFT 132
N L GH+ V +V WNE YQKL T D +G I VW+ Y+G W E++N+R + V +
Sbjct: 63 MNQTLEGHSGSVQVVTWNEQYQKLTTSDENGLIIVWMLYKGSWIEEMINNRNKSVVRSMS 122
Query: 133 WSHDGTQALISYRDGFVLVGSVSGQRHWSSEINLESQITCGIWTPDDQQVLFGTADGQVI 192
W+ DG + I Y DG V+VGSV G R W ++ Q++ W+ D + +LFG A+G++
Sbjct: 123 WNADGQKICIVYEDGAVIVGSVDGNRIWGKDLK-GIQLSHVTWSADSKVLLFGMANGEIH 181
Query: 193 VMDCHGRMLAHVLLH------ESDGVLGMSWNYPIFLVEDSSESDTDSDDYAPPQDGPAA 246
+ D G + + L + + G+ W + ++ Y P
Sbjct: 182 IYDNQGNFMIKMKLSCLVNVTGAISIAGIHWYH-------------GTEGYVEPD----- 223
Query: 247 YPIPVQNIKPLLTVSFTSGDISLMNNYDDLSPTVIRSGLKEVVAQWCTQGDLLAVAGMER 306
P L V F +G +M + +D +P +I +G+ V QW G +LAVAG ++
Sbjct: 224 --------CPCLAVCFDNGRCQIMRHENDQNPVLIDTGMYVVGIQWNHMGSVLAVAGFQK 275
Query: 307 QTQLGELPNGPLLKSAMVKFYNVRGEHIFTLDTLVQRPIISICWGHRDSRLLMASGPALY 366
+ N +V+FY GEH+ TL + + I ++ W ++ +A +Y
Sbjct: 276 AAMQDKDVN-------IVQFYTPFGEHLGTL-KVPGKEISALSWEGGGLKIALAVDSFIY 327
Query: 367 VVRV 370
+
Sbjct: 328 FANI 331
>gi|16554629 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 50.4 bits (119), Expect = 5e-06
Identities = 41/172 (23%), Positives = 73/172 (42%), Gaps = 5/172 (2%)
Query: 61 SSHCRRDRSTPQRIN----FNLRGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEGRW 116
SS + + TP + N F L GH V V+++ + LA+ AD I +W Y+G++
Sbjct: 20 SSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKF 79
Query: 117 SVELVNDRGAQVSDFTWSHDGTQALISYRDGFVLVGSVSGQRHWSSEINLESQITCGIWT 176
+ ++ +SD WS D + + D + + VS + + + + C +
Sbjct: 80 E-KTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFN 138
Query: 177 PDDQQVLFGTADGQVIVMDCHGRMLAHVLLHESDGVLGMSWNYPIFLVEDSS 228
P ++ G+ D V + D L SD V + +N L+ SS
Sbjct: 139 PQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSS 190
>gi|16554627 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 50.4 bits (119), Expect = 5e-06
Identities = 41/172 (23%), Positives = 73/172 (42%), Gaps = 5/172 (2%)
Query: 61 SSHCRRDRSTPQRIN----FNLRGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEGRW 116
SS + + TP + N F L GH V V+++ + LA+ AD I +W Y+G++
Sbjct: 20 SSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKF 79
Query: 117 SVELVNDRGAQVSDFTWSHDGTQALISYRDGFVLVGSVSGQRHWSSEINLESQITCGIWT 176
+ ++ +SD WS D + + D + + VS + + + + C +
Sbjct: 80 E-KTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFN 138
Query: 177 PDDQQVLFGTADGQVIVMDCHGRMLAHVLLHESDGVLGMSWNYPIFLVEDSS 228
P ++ G+ D V + D L SD V + +N L+ SS
Sbjct: 139 PQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSS 190
>gi|23199987 WD repeat domain 5B [Homo sapiens]
Length = 330
Score = 49.7 bits (117), Expect = 9e-06
Identities = 38/177 (21%), Positives = 73/177 (41%), Gaps = 5/177 (2%)
Query: 46 LATGNGRGVVGVTFTSSHCRRDRSTPQRINFNLR----GHNSEVVLVRWNEPYQKLATCD 101
+AT R SS + + P+ N+ L+ GH V V+++ + LA+
Sbjct: 1 MATKESRDAKAQLALSSSANQSKEVPENPNYALKCTLVGHTEAVSSVKFSPNGEWLASSS 60
Query: 102 ADGGIFVWIQYEGRWSVELVNDRGAQVSDFTWSHDGTQALISYRDGFVLVGSVSGQRHWS 161
AD I +W Y+G++ L ++SD WS D ++ + + D + + V +
Sbjct: 61 ADRLIIIWGAYDGKYEKTLYG-HNLEISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLK 119
Query: 162 SEINLESQITCGIWTPDDQQVLFGTADGQVIVMDCHGRMLAHVLLHESDGVLGMSWN 218
+ + + C + P ++ G+ D V + + L SD V + +N
Sbjct: 120 TLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVKTGKCLKTLSAHSDPVSAVHFN 176
>gi|22907052 actin related protein 2/3 complex subunit 1A [Homo
sapiens]
Length = 370
Score = 42.0 bits (97), Expect = 0.002
Identities = 49/230 (21%), Positives = 84/230 (36%), Gaps = 33/230 (14%)
Query: 78 LRGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEGRWSVELVNDRGAQVSDFT-WSHD 136
L+ HN + + W ++ TC AD +VW Q +G W LV R + + F WS
Sbjct: 48 LKEHNGHITGIDWAPKSDRIVTCGADRNAYVWSQKDGVWKPTLVILRINRAATFVKWSPL 107
Query: 137 GTQALISYRDGFVLVGSVSGQRHWSSEINLESQITCGI----WTPDDQQVLFGTADGQVI 192
+ + + V + W +++ I + W P++ + G+ D +
Sbjct: 108 ENKFAVGSGARLISVCYFESENDWWVSKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKCR 167
Query: 193 VMDCH--------------GRMLAHVLLHESDGVLGMSWNYPIFLVEDSSESDTDSDDYA 238
V + +M L+ E G W + + S S D +
Sbjct: 168 VFSAYIKEVDEKPASTPWGSKMPFGQLMSEFGGSGTGGWVHGVSFSASGSRLAWVSHD-S 226
Query: 239 PPQDGPAAYPIPVQNIK----PLLTVSFTSGD---------ISLMNNYDD 275
A+ + V +K PLL+VSF S + ++ NYDD
Sbjct: 227 TVSVADASKSVQVSTLKTEFLPLLSVSFVSENSVVAAGHDCCPMLFNYDD 276
>gi|37620163 ANKHD1-EIF4EBP3 protein [Homo sapiens]
Length = 2617
Score = 39.7 bits (91), Expect = 0.009
Identities = 43/169 (25%), Positives = 66/169 (39%), Gaps = 25/169 (14%)
Query: 426 MRDFVSYPSAGNERLHCTMKRTEDDPEVGGPCYTLYLEYLGGLVPILKGRRISKLRPEFV 485
M +S PS ++ H M+R DD + P + G V KG IS +
Sbjct: 2425 MHQQLSDPSTFSQ--HQPMER--DDSGMVAPSNIFHQPMASGFVDFSKGLPISMYGGTII 2480
Query: 486 IMDPRTDS-----------KPDEIYGNSLISTVIDSCNCSDSSDIELSDDWAAKK----S 530
P+ PD + N +I + +S C+D+ L A K S
Sbjct: 2481 PSHPQLADVPGGPLFNGLHNPDPAW-NPMIKVIQNSTECTDAQQASLLPSVPALKGEIPS 2539
Query: 531 PKISRASKSPKLPRISIEARKS-----PKLPRAAQELSRSPRLPLRKPS 574
P+++R K P ++ ++ PK+P QEL+ P PL PS
Sbjct: 2540 PQLTRPKKRIGRPMVASPNQRHQDHLRPKVPAGVQELTHCPDTPLLPPS 2588
>gi|19913367 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 39.7 bits (91), Expect = 0.009
Identities = 41/160 (25%), Positives = 51/160 (31%), Gaps = 28/160 (17%)
Query: 78 LRGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEGR--WSVELV-----------NDR 124
LRGH SEV + WN LA+ D +W E S +LV
Sbjct: 175 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 234
Query: 125 GAQVSDFTWSHDGTQALISYRDGFVLVGSVSGQRHWSSEINLES-------QITCGIWTP 177
V+ W+ DGT + DGF R W+ NL S I W
Sbjct: 235 NKDVTSLDWNSDGTLLAMGSYDGFA--------RIWTENGNLASTLGQHKGPIFALKWNK 286
Query: 178 DDQQVLFGTADGQVIVMDCHGRMLAHVLLHESDGVLGMSW 217
VL D I+ D H S L + W
Sbjct: 287 KGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDW 326
Score = 32.7 bits (73), Expect = 1.1
Identities = 30/151 (19%), Positives = 59/151 (39%), Gaps = 15/151 (9%)
Query: 79 RGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEGRWSVELVNDRGAQVSDFTWSHDGT 138
+GH +EV ++W+ LA+C D + +W + V + ++ WS G
Sbjct: 356 QGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDA-CVHDLQAHSKEIYTIKWSPTGP 414
Query: 139 QALISYRDGFVLVGSVSGQ---RHWSSE--------INLESQITCGIWTPDDQQVLFGTA 187
S + +++ S S R W E + + + ++PD + + G+
Sbjct: 415 AT--SNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLASGSF 472
Query: 188 DGQVIVMDCHGRMLAHVLLHESDGVLGMSWN 218
D V + + L H + G+ + WN
Sbjct: 473 DKYVHIWNTQSGSLVH-SYQGTGGIFEVCWN 502
>gi|19913365 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 39.7 bits (91), Expect = 0.009
Identities = 41/160 (25%), Positives = 51/160 (31%), Gaps = 28/160 (17%)
Query: 78 LRGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEGR--WSVELV-----------NDR 124
LRGH SEV + WN LA+ D +W E S +LV
Sbjct: 175 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 234
Query: 125 GAQVSDFTWSHDGTQALISYRDGFVLVGSVSGQRHWSSEINLES-------QITCGIWTP 177
V+ W+ DGT + DGF R W+ NL S I W
Sbjct: 235 NKDVTSLDWNSDGTLLAMGSYDGFA--------RIWTENGNLASTLGQHKGPIFALKWNK 286
Query: 178 DDQQVLFGTADGQVIVMDCHGRMLAHVLLHESDGVLGMSW 217
VL D I+ D H S L + W
Sbjct: 287 KGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDW 326
Score = 32.7 bits (73), Expect = 1.1
Identities = 30/151 (19%), Positives = 59/151 (39%), Gaps = 15/151 (9%)
Query: 79 RGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEGRWSVELVNDRGAQVSDFTWSHDGT 138
+GH +EV ++W+ LA+C D + +W + V + ++ WS G
Sbjct: 356 QGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDA-CVHDLQAHSKEIYTIKWSPTGP 414
Query: 139 QALISYRDGFVLVGSVSGQ---RHWSSE--------INLESQITCGIWTPDDQQVLFGTA 187
S + +++ S S R W E + + + ++PD + + G+
Sbjct: 415 AT--SNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLASGSF 472
Query: 188 DGQVIVMDCHGRMLAHVLLHESDGVLGMSWN 218
D V + + L H + G+ + WN
Sbjct: 473 DKYVHIWNTQSGSLVH-SYQGTGGIFEVCWN 502
>gi|15150805 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 39.7 bits (91), Expect = 0.009
Identities = 41/160 (25%), Positives = 51/160 (31%), Gaps = 28/160 (17%)
Query: 78 LRGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEGR--WSVELV-----------NDR 124
LRGH SEV + WN LA+ D +W E S +LV
Sbjct: 175 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 234
Query: 125 GAQVSDFTWSHDGTQALISYRDGFVLVGSVSGQRHWSSEINLES-------QITCGIWTP 177
V+ W+ DGT + DGF R W+ NL S I W
Sbjct: 235 NKDVTSLDWNSDGTLLAMGSYDGFA--------RIWTENGNLASTLGQHKGPIFALKWNK 286
Query: 178 DDQQVLFGTADGQVIVMDCHGRMLAHVLLHESDGVLGMSW 217
VL D I+ D H S L + W
Sbjct: 287 KGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDW 326
Score = 32.7 bits (73), Expect = 1.1
Identities = 30/151 (19%), Positives = 59/151 (39%), Gaps = 15/151 (9%)
Query: 79 RGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEGRWSVELVNDRGAQVSDFTWSHDGT 138
+GH +EV ++W+ LA+C D + +W + V + ++ WS G
Sbjct: 356 QGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDA-CVHDLQAHSKEIYTIKWSPTGP 414
Query: 139 QALISYRDGFVLVGSVSGQ---RHWSSE--------INLESQITCGIWTPDDQQVLFGTA 187
S + +++ S S R W E + + + ++PD + + G+
Sbjct: 415 AT--SNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLASGSF 472
Query: 188 DGQVIVMDCHGRMLAHVLLHESDGVLGMSWN 218
D V + + L H + G+ + WN
Sbjct: 473 DKYVHIWNTQSGSLVH-SYQGTGGIFEVCWN 502
>gi|210032390 SEC13 protein isoform 2 [Homo sapiens]
Length = 308
Score = 38.9 bits (89), Expect = 0.016
Identities = 32/118 (27%), Positives = 49/118 (41%), Gaps = 8/118 (6%)
Query: 68 RSTPQRINFNLRGHNSEVVLVRWNEPYQK--LATCDADGGIFVWIQYEGRWSVELVN-DR 124
R+ Q + +LRGH V V W P LA+C D + +W + G W +
Sbjct: 29 RNGGQILIADLRGHEGPVWQVAWAHPMYGNILASCSYDRKVIIWREENGTWEKSHEHAGH 88
Query: 125 GAQVSDFTWS-HD-GTQALISYRDGFVLVGSVSGQRHWS-SEINLESQITCGI--WTP 177
+ V+ W+ HD G DG + + + +G+ W +IN I C W P
Sbjct: 89 DSSVNSVCWAPHDYGLILACGSSDGAISLLTYTGEGQWEVKKINNAHTIGCNAVSWAP 146
Score = 32.3 bits (72), Expect = 1.5
Identities = 27/97 (27%), Positives = 40/97 (41%), Gaps = 9/97 (9%)
Query: 78 LRGHNSEVVLVRWNE----PYQKLATCDADGGIFVWI---QYEGRWSVELVNDRGAQVSD 130
L H+ V V W P +A+C DG +F+W WS +L++ V
Sbjct: 194 LEAHSDWVRDVAWAPSIGLPTSTIASCSQDGRVFIWTCDDASSNTWSPKLLHKFNDVVWH 253
Query: 131 FTWSHDGTQALISYRDGFVLV--GSVSGQRHWSSEIN 165
+WS +S D V + SV GQ S++N
Sbjct: 254 VSWSITANILAVSGGDNKVTLWKESVDGQWVCISDVN 290
>gi|34335134 SEC13 protein isoform 1 [Homo sapiens]
Length = 322
Score = 38.9 bits (89), Expect = 0.016
Identities = 32/118 (27%), Positives = 49/118 (41%), Gaps = 8/118 (6%)
Query: 68 RSTPQRINFNLRGHNSEVVLVRWNEPYQK--LATCDADGGIFVWIQYEGRWSVELVN-DR 124
R+ Q + +LRGH V V W P LA+C D + +W + G W +
Sbjct: 43 RNGGQILIADLRGHEGPVWQVAWAHPMYGNILASCSYDRKVIIWREENGTWEKSHEHAGH 102
Query: 125 GAQVSDFTWS-HD-GTQALISYRDGFVLVGSVSGQRHWS-SEINLESQITCGI--WTP 177
+ V+ W+ HD G DG + + + +G+ W +IN I C W P
Sbjct: 103 DSSVNSVCWAPHDYGLILACGSSDGAISLLTYTGEGQWEVKKINNAHTIGCNAVSWAP 160
Score = 32.3 bits (72), Expect = 1.5
Identities = 27/97 (27%), Positives = 40/97 (41%), Gaps = 9/97 (9%)
Query: 78 LRGHNSEVVLVRWNE----PYQKLATCDADGGIFVWI---QYEGRWSVELVNDRGAQVSD 130
L H+ V V W P +A+C DG +F+W WS +L++ V
Sbjct: 208 LEAHSDWVRDVAWAPSIGLPTSTIASCSQDGRVFIWTCDDASSNTWSPKLLHKFNDVVWH 267
Query: 131 FTWSHDGTQALISYRDGFVLV--GSVSGQRHWSSEIN 165
+WS +S D V + SV GQ S++N
Sbjct: 268 VSWSITANILAVSGGDNKVTLWKESVDGQWVCISDVN 304
>gi|109948304 smu-1 suppressor of mec-8 and unc-52 homolog [Homo
sapiens]
Length = 513
Score = 37.7 bits (86), Expect = 0.035
Identities = 36/163 (22%), Positives = 67/163 (41%), Gaps = 3/163 (1%)
Query: 30 EKEKPVCRRRYYEEGWLATGNGRGVVGV-TFTSSHCRRDRSTPQRINFNLRGHNSEVVLV 88
+K C R + +L TG+ G + V FT+ R+D + NF + + V+ +
Sbjct: 213 QKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMM--DDAVLCM 270
Query: 89 RWNEPYQKLATCDADGGIFVWIQYEGRWSVELVNDRGAQVSDFTWSHDGTQALISYRDGF 148
++ + LAT DG I VW G+ V+ ++S D +Q L + D
Sbjct: 271 CFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQT 330
Query: 149 VLVGSVSGQRHWSSEINLESQITCGIWTPDDQQVLFGTADGQV 191
+ + + + S + +T D ++ ++DG V
Sbjct: 331 IRIHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTV 373
>gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo
sapiens]
Length = 514
Score = 37.4 bits (85), Expect = 0.046
Identities = 41/160 (25%), Positives = 53/160 (33%), Gaps = 28/160 (17%)
Query: 78 LRGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEG--RWSVELV----NDRGAQ---- 127
LRGH SEV + WN LA+ D +W E S +LV G Q
Sbjct: 165 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPS 224
Query: 128 ---VSDFTWSHDGTQALISYRDGFVLVGSVSGQRHWSSEINLES-------QITCGIWTP 177
V+ W+ +GT DGF R W+ + NL S I W
Sbjct: 225 NKDVTSLDWNSEGTLLATGSYDGFA--------RIWTKDGNLASTLGQHKGPIFALKWNK 276
Query: 178 DDQQVLFGTADGQVIVMDCHGRMLAHVLLHESDGVLGMSW 217
+L D I+ D H S L + W
Sbjct: 277 KGNFILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDW 316
>gi|213021190 transducin beta-like 1X isoform b [Homo sapiens]
Length = 526
Score = 36.6 bits (83), Expect = 0.078
Identities = 39/160 (24%), Positives = 51/160 (31%), Gaps = 28/160 (17%)
Query: 78 LRGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEGR--WSVELV-----------NDR 124
LRGH SEV + WN LA+ D +W E S +LV
Sbjct: 177 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 236
Query: 125 GAQVSDFTWSHDGTQALISYRDGFVLVGSVSGQRHWSSEINLES-------QITCGIWTP 177
V+ W+ +GT DGF R W+ + NL S I W
Sbjct: 237 NKDVTSLDWNTNGTLLATGSYDGFA--------RIWTEDGNLASTLGQHKGPIFALKWNR 288
Query: 178 DDQQVLFGTADGQVIVMDCHGRMLAHVLLHESDGVLGMSW 217
+L D I+ D H S L + W
Sbjct: 289 KGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDW 328
Score = 30.4 bits (67), Expect = 5.6
Identities = 29/151 (19%), Positives = 59/151 (39%), Gaps = 15/151 (9%)
Query: 79 RGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEGRWSVELVNDRGAQVSDFTWSHDGT 138
+GH +EV ++W+ LA+C D + +W + + + ++ WS G
Sbjct: 358 QGHTNEVNAIKWDPSGMLLASCSDDMTLKIW-SMKQEVCIHDLQAHNKEIYTIKWSPTGP 416
Query: 139 QALISYRDGFVLVGSVSGQ---RHWSSEINL--------ESQITCGIWTPDDQQVLFGTA 187
S + +++ S S R W E + + + ++PD + + G+
Sbjct: 417 AT--SNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSF 474
Query: 188 DGQVIVMDCHGRMLAHVLLHESDGVLGMSWN 218
D V + + L H + G+ + WN
Sbjct: 475 DKCVHIWNTQSGNLVH-SYRGTGGIFEVCWN 504
>gi|213021188 transducin beta-like 1X isoform b [Homo sapiens]
Length = 526
Score = 36.6 bits (83), Expect = 0.078
Identities = 39/160 (24%), Positives = 51/160 (31%), Gaps = 28/160 (17%)
Query: 78 LRGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEGR--WSVELV-----------NDR 124
LRGH SEV + WN LA+ D +W E S +LV
Sbjct: 177 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 236
Query: 125 GAQVSDFTWSHDGTQALISYRDGFVLVGSVSGQRHWSSEINLES-------QITCGIWTP 177
V+ W+ +GT DGF R W+ + NL S I W
Sbjct: 237 NKDVTSLDWNTNGTLLATGSYDGFA--------RIWTEDGNLASTLGQHKGPIFALKWNR 288
Query: 178 DDQQVLFGTADGQVIVMDCHGRMLAHVLLHESDGVLGMSW 217
+L D I+ D H S L + W
Sbjct: 289 KGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDW 328
Score = 30.4 bits (67), Expect = 5.6
Identities = 29/151 (19%), Positives = 59/151 (39%), Gaps = 15/151 (9%)
Query: 79 RGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEGRWSVELVNDRGAQVSDFTWSHDGT 138
+GH +EV ++W+ LA+C D + +W + + + ++ WS G
Sbjct: 358 QGHTNEVNAIKWDPSGMLLASCSDDMTLKIW-SMKQEVCIHDLQAHNKEIYTIKWSPTGP 416
Query: 139 QALISYRDGFVLVGSVSGQ---RHWSSEINL--------ESQITCGIWTPDDQQVLFGTA 187
S + +++ S S R W E + + + ++PD + + G+
Sbjct: 417 AT--SNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSF 474
Query: 188 DGQVIVMDCHGRMLAHVLLHESDGVLGMSWN 218
D V + + L H + G+ + WN
Sbjct: 475 DKCVHIWNTQSGNLVH-SYRGTGGIFEVCWN 504
>gi|213021186 transducin beta-like 1X isoform a [Homo sapiens]
Length = 577
Score = 36.6 bits (83), Expect = 0.078
Identities = 39/160 (24%), Positives = 51/160 (31%), Gaps = 28/160 (17%)
Query: 78 LRGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEGR--WSVELV-----------NDR 124
LRGH SEV + WN LA+ D +W E S +LV
Sbjct: 228 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 287
Query: 125 GAQVSDFTWSHDGTQALISYRDGFVLVGSVSGQRHWSSEINLES-------QITCGIWTP 177
V+ W+ +GT DGF R W+ + NL S I W
Sbjct: 288 NKDVTSLDWNTNGTLLATGSYDGFA--------RIWTEDGNLASTLGQHKGPIFALKWNR 339
Query: 178 DDQQVLFGTADGQVIVMDCHGRMLAHVLLHESDGVLGMSW 217
+L D I+ D H S L + W
Sbjct: 340 KGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDW 379
Score = 30.4 bits (67), Expect = 5.6
Identities = 29/151 (19%), Positives = 59/151 (39%), Gaps = 15/151 (9%)
Query: 79 RGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEGRWSVELVNDRGAQVSDFTWSHDGT 138
+GH +EV ++W+ LA+C D + +W + + + ++ WS G
Sbjct: 409 QGHTNEVNAIKWDPSGMLLASCSDDMTLKIW-SMKQEVCIHDLQAHNKEIYTIKWSPTGP 467
Query: 139 QALISYRDGFVLVGSVSGQ---RHWSSEINL--------ESQITCGIWTPDDQQVLFGTA 187
S + +++ S S R W E + + + ++PD + + G+
Sbjct: 468 AT--SNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSF 525
Query: 188 DGQVIVMDCHGRMLAHVLLHESDGVLGMSWN 218
D V + + L H + G+ + WN
Sbjct: 526 DKCVHIWNTQSGNLVH-SYRGTGGIFEVCWN 555
>gi|5032159 transducin beta-like 1X isoform a [Homo sapiens]
Length = 577
Score = 36.6 bits (83), Expect = 0.078
Identities = 39/160 (24%), Positives = 51/160 (31%), Gaps = 28/160 (17%)
Query: 78 LRGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEGR--WSVELV-----------NDR 124
LRGH SEV + WN LA+ D +W E S +LV
Sbjct: 228 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 287
Query: 125 GAQVSDFTWSHDGTQALISYRDGFVLVGSVSGQRHWSSEINLES-------QITCGIWTP 177
V+ W+ +GT DGF R W+ + NL S I W
Sbjct: 288 NKDVTSLDWNTNGTLLATGSYDGFA--------RIWTEDGNLASTLGQHKGPIFALKWNR 339
Query: 178 DDQQVLFGTADGQVIVMDCHGRMLAHVLLHESDGVLGMSW 217
+L D I+ D H S L + W
Sbjct: 340 KGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDW 379
Score = 30.4 bits (67), Expect = 5.6
Identities = 29/151 (19%), Positives = 59/151 (39%), Gaps = 15/151 (9%)
Query: 79 RGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEGRWSVELVNDRGAQVSDFTWSHDGT 138
+GH +EV ++W+ LA+C D + +W + + + ++ WS G
Sbjct: 409 QGHTNEVNAIKWDPSGMLLASCSDDMTLKIW-SMKQEVCIHDLQAHNKEIYTIKWSPTGP 467
Query: 139 QALISYRDGFVLVGSVSGQ---RHWSSEINL--------ESQITCGIWTPDDQQVLFGTA 187
S + +++ S S R W E + + + ++PD + + G+
Sbjct: 468 AT--SNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSF 525
Query: 188 DGQVIVMDCHGRMLAHVLLHESDGVLGMSWN 218
D V + + L H + G+ + WN
Sbjct: 526 DKCVHIWNTQSGNLVH-SYRGTGGIFEVCWN 555
>gi|4757988 WD repeat domain 39 [Homo sapiens]
Length = 339
Score = 35.4 bits (80), Expect = 0.17
Identities = 22/68 (32%), Positives = 30/68 (44%), Gaps = 3/68 (4%)
Query: 78 LRGHNSEVVLVRWNEPYQKLATCDADGGIFVW-IQYEGRWS-VELVNDRGAQVSDFTWSH 135
L GH +EV V W LATC D ++VW + E + V ++N V W H
Sbjct: 101 LEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEEDEYECVSVLNSHTQDVKHVVW-H 159
Query: 136 DGTQALIS 143
+ L S
Sbjct: 160 PSQELLAS 167
Score = 29.6 bits (65), Expect = 9.6
Identities = 13/35 (37%), Positives = 20/35 (57%)
Query: 78 LRGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQY 112
L GH S V + ++ Q+LA+C D + +W QY
Sbjct: 190 LEGHESTVWSLAFDPSGQRLASCSDDRTVRIWRQY 224
>gi|24430146 nucleoporin 153kDa [Homo sapiens]
Length = 1475
Score = 34.7 bits (78), Expect = 0.30
Identities = 25/82 (30%), Positives = 39/82 (47%), Gaps = 1/82 (1%)
Query: 500 GNSLISTVIDSCNCSDSSDIELSDDWAAKKSPKISRASKSPKLPRI-SIEARKSPKLPRA 558
G SL+ + DS + D +I + ++++ S K SK+ LP + S EA +S L +
Sbjct: 162 GFSLVKEIKDSTSQHDDDNISTTSGFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQH 221
Query: 559 AQELSRSPRLPLRKPSVGSPSL 580
S+ P L SPSL
Sbjct: 222 TATSSKKPAFNLSAFGTLSPSL 243
>gi|238859545 tubby like protein 2 [Homo sapiens]
Length = 520
Score = 34.3 bits (77), Expect = 0.39
Identities = 22/63 (34%), Positives = 34/63 (53%), Gaps = 13/63 (20%)
Query: 594 NYLAQVTSNIWGTKFKI------------VGLAAFLPTNLGAVIYKTSLL-HLQPRQMTI 640
N++ +V SN++ TKF I A + LGAV Y+ ++L +L PR+MT+
Sbjct: 348 NFVGKVRSNVFSTKFTIFDNGVNPDREHLTRNTARIRQELGAVCYEPNVLGYLGPRKMTV 407
Query: 641 YLP 643
LP
Sbjct: 408 ILP 410
>gi|51242945 striatin, calmodulin binding protein [Homo sapiens]
Length = 780
Score = 34.3 bits (77), Expect = 0.39
Identities = 26/107 (24%), Positives = 48/107 (44%), Gaps = 6/107 (5%)
Query: 67 DRSTPQRINFNLRGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEGRWSVELVNDR-- 124
D P + L GH V + ++ +Q+L +C ADG + +W E ++ + ND
Sbjct: 554 DSYDPSVLRGPLLGHTDAVWGLAYSAAHQRLLSCSADGTLRLWNTTEVAPALSVFNDTKE 613
Query: 125 -GAQVSDFTWSHDGTQALISYRDGFVLVGSVSGQRHWSSEINLESQI 170
G S S D + + S+ G+ + ++ Q+ + LES +
Sbjct: 614 LGIPASVDLVSSDPSHMVASFSKGYTSIFNMETQQR---ILTLESNV 657
>gi|32189425 WD repeat domain 69 [Homo sapiens]
Length = 415
Score = 34.3 bits (77), Expect = 0.39
Identities = 32/154 (20%), Positives = 60/154 (38%), Gaps = 1/154 (0%)
Query: 79 RGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEGRWSVELVNDRGAQVSDFTWSHDGT 138
RGH +E+V + +N +AT D +W G V + A++ +++ G
Sbjct: 174 RGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGE-EVYTLRGHSAEIISLSFNTSGD 232
Query: 139 QALISYRDGFVLVGSVSGQRHWSSEINLESQITCGIWTPDDQQVLFGTADGQVIVMDCHG 198
+ + D V+V R + I ++I+ + D +L G+ D + D
Sbjct: 233 RIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATN 292
Query: 199 RMLAHVLLHESDGVLGMSWNYPIFLVEDSSESDT 232
L D +L ++Y L+ +S T
Sbjct: 293 GKCVATLTGHDDEILDSCFDYTGKLIATASADGT 326
Score = 32.7 bits (73), Expect = 1.1
Identities = 34/198 (17%), Positives = 69/198 (34%), Gaps = 41/198 (20%)
Query: 76 FNLRGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEGR------------------WS 117
+ LRGH++E++ + +N ++ T D + VW GR W
Sbjct: 213 YTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWD 272
Query: 118 VELV-----------------------NDRGAQVSDFTWSHDGTQALISYRDGFVLVGSV 154
L+ ++ D + + G + DG + S
Sbjct: 273 CSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTARIFSA 332
Query: 155 SGQRHWSSEINLESQITCGIWTPDDQQVLFGTADGQVIVMDCHGRMLAHVLLHESDGVLG 214
+ ++ + E +I+ + P +L G++D + D VL +D +
Sbjct: 333 ATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDEIFS 392
Query: 215 MSWNYPIFLVEDSSESDT 232
++NY +V S+ +T
Sbjct: 393 CAFNYKGNIVITGSKDNT 410
Score = 30.8 bits (68), Expect = 4.3
Identities = 44/178 (24%), Positives = 73/178 (41%), Gaps = 25/178 (14%)
Query: 67 DRSTPQRINFNLRGHNSEVVLVRWNEPY-QKLATCDADGGIFVWIQYEGR-------WSV 118
D ++ + +N L GH + V + +N PY K+AT D +W G+ +
Sbjct: 120 DTASGEELN-TLEGHRNVVYAIAFNNPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTA 178
Query: 119 ELV----NDRGAQVSDFTWSHDGTQALISYRDGFVLVGSVSGQRHWSSEINLESQITCGI 174
E+V N + V+ T S D T L ++G V R S+EI S T G
Sbjct: 179 EIVCLSFNPQSTLVA--TGSMDTTAKLWDIQNG----EEVYTLRGHSAEIISLSFNTSG- 231
Query: 175 WTPDDQQVLFGTADGQVIVMDCHGRMLAHVLLHESDGVLGMSWNYPIFLVEDSSESDT 232
+++ G+ D V+V D ++L+ + S+N+ L+ S T
Sbjct: 232 -----DRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKT 284
>gi|209969680 Fzr1 protein isoform 1 [Homo sapiens]
Length = 496
Score = 33.9 bits (76), Expect = 0.51
Identities = 19/67 (28%), Positives = 31/67 (46%), Gaps = 1/67 (1%)
Query: 68 RSTPQRINFNLRGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEGRWSVELVNDRGAQ 127
R+ P + L+GH EV ++W+ +Q LA+ D + VW + V+ + A
Sbjct: 299 RTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVW-NHSSLSPVQQYTEHLAA 357
Query: 128 VSDFTWS 134
V WS
Sbjct: 358 VKAIAWS 364
>gi|209969678 Fzr1 protein isoform 3 [Homo sapiens]
Length = 404
Score = 33.9 bits (76), Expect = 0.51
Identities = 19/67 (28%), Positives = 31/67 (46%), Gaps = 1/67 (1%)
Query: 68 RSTPQRINFNLRGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEGRWSVELVNDRGAQ 127
R+ P + L+GH EV ++W+ +Q LA+ D + VW + V+ + A
Sbjct: 210 RTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVW-NHSSLSPVQQYTEHLAA 268
Query: 128 VSDFTWS 134
V WS
Sbjct: 269 VKAIAWS 275
>gi|33620742 Fzr1 protein isoform 2 [Homo sapiens]
Length = 493
Score = 33.9 bits (76), Expect = 0.51
Identities = 19/67 (28%), Positives = 31/67 (46%), Gaps = 1/67 (1%)
Query: 68 RSTPQRINFNLRGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEGRWSVELVNDRGAQ 127
R+ P + L+GH EV ++W+ +Q LA+ D + VW + V+ + A
Sbjct: 299 RTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVW-NHSSLSPVQQYTEHLAA 357
Query: 128 VSDFTWS 134
V WS
Sbjct: 358 VKAIAWS 364
>gi|16418439 WD repeat and FYVE domain containing 2 [Homo sapiens]
Length = 400
Score = 33.9 bits (76), Expect = 0.51
Identities = 19/60 (31%), Positives = 32/60 (53%), Gaps = 3/60 (5%)
Query: 78 LRGHNSEVVLVRWNEPYQKLATCDADGGIFVW-IQYEGRWSVELVNDRGAQVSD--FTWS 134
L+GHN V + + + ++L +C DGGI VW + E + + E ++ Q D F W+
Sbjct: 238 LQGHNDRVQALSYAQHTRQLISCGGDGGIVVWNMDVERQETPEWLDSDSCQKCDQPFFWN 297
>gi|18254460 splA/ryanodine receptor domain and SOCS box containing
4 [Homo sapiens]
Length = 273
Score = 33.5 bits (75), Expect = 0.66
Identities = 31/113 (27%), Positives = 52/113 (46%), Gaps = 21/113 (18%)
Query: 298 LLAVAGMERQTQLGELPNGPLLKSAMVKFYNVRGEHIFTLDTLVQRPIISICWGHRDSRL 357
LL V M+ T L + +G L V F ++G+ ++ P++S WGH + +
Sbjct: 177 LLVVLDMDEGT-LSFIVDGQYLG---VAFRGLKGKKLY--------PVVSAVWGHCEVTM 224
Query: 358 LMASGPALYVVRVEHRVSSLQLLCQQAIASTLREDK--DVSKLTLPPRLCSYL 408
Y+ ++ L LC+++I S L + D+S L LP L +YL
Sbjct: 225 -------RYINGLDPEPLPLMDLCRRSIRSALGRQRLQDISSLPLPQSLKNYL 270
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.420
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,997,950
Number of Sequences: 37866
Number of extensions: 1324887
Number of successful extensions: 4020
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 38
Number of HSP's successfully gapped in prelim test: 79
Number of HSP's that attempted gapping in prelim test: 3813
Number of HSP's gapped (non-prelim): 248
length of query: 678
length of database: 18,247,518
effective HSP length: 109
effective length of query: 569
effective length of database: 14,120,124
effective search space: 8034350556
effective search space used: 8034350556
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.