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Search of human proteins with 54873613
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|54873613 agrin [Homo sapiens]
(2045 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|54873613 agrin [Homo sapiens] 4305 0.0
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 330 1e-89
gi|33469931 EGF-like, fibronectin type III and laminin G domains... 328 4e-89
gi|33469929 EGF-like, fibronectin type III and laminin G domains... 328 4e-89
gi|33469935 EGF-like, fibronectin type III and laminin G domains... 206 2e-52
gi|224451128 eyes shut homolog isoform 1 [Homo sapiens] 202 2e-51
gi|14211536 neurexin 2 isoform alpha-1 precursor [Homo sapiens] 167 1e-40
gi|21166380 neurexin 2 isoform alpha-2 precursor [Homo sapiens] 162 3e-39
gi|14149613 neurexin 1 isoform alpha1 precursor [Homo sapiens] 137 8e-32
gi|188528675 slit homolog 1 [Homo sapiens] 137 1e-31
gi|208609951 neurexin 1 isoform alpha2 precursor [Homo sapiens] 134 1e-30
gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens] 133 2e-30
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 127 1e-28
gi|134244285 Notch homolog 3 [Homo sapiens] 127 1e-28
gi|5453652 follistatin isoform FST317 precursor [Homo sapiens] 122 4e-27
gi|7242222 follistatin isoform FST344 precursor [Homo sapiens] 122 4e-27
gi|4759146 slit homolog 2 [Homo sapiens] 122 5e-27
gi|165932370 FAT tumor suppressor homolog 4 [Homo sapiens] 119 4e-26
gi|13325064 cadherin EGF LAG seven-pass G-type receptor 2 [Homo ... 117 2e-25
gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo... 113 2e-24
gi|148833508 notch1 preproprotein [Homo sapiens] 112 4e-24
gi|55770876 notch4 preproprotein [Homo sapiens] 112 5e-24
gi|119703755 laminin, beta 2 precursor [Homo sapiens] 110 1e-23
gi|148886692 FAT tumor suppressor homolog 3 [Homo sapiens] 110 2e-23
gi|12383051 transmembrane protein with EGF-like and two follista... 109 3e-23
gi|24041035 notch 2 preproprotein [Homo sapiens] 109 3e-23
gi|41327708 crumbs homolog 1 precursor [Homo sapiens] 109 3e-23
gi|122937343 platelet endothelial aggregation receptor 1 [Homo s... 108 4e-23
gi|38788416 laminin, alpha 1 precursor [Homo sapiens] 108 5e-23
gi|110611156 laminin, gamma 3 precursor [Homo sapiens] 107 1e-22
>gi|54873613 agrin [Homo sapiens]
Length = 2045
Score = 4305 bits (11165), Expect = 0.0
Identities = 2045/2045 (100%), Positives = 2045/2045 (100%)
Query: 1 MAGRSHPGPLRPLLPLLVVAACVLPGAGGTCPERALERREEEANVVLTGTVEEILNVDPV 60
MAGRSHPGPLRPLLPLLVVAACVLPGAGGTCPERALERREEEANVVLTGTVEEILNVDPV
Sbjct: 1 MAGRSHPGPLRPLLPLLVVAACVLPGAGGTCPERALERREEEANVVLTGTVEEILNVDPV 60
Query: 61 QHTYSCKVRVWRYLKGKDLVARESLLDGGNKVVISGFGDPLICDNQVSTGDTRIFFVNPA 120
QHTYSCKVRVWRYLKGKDLVARESLLDGGNKVVISGFGDPLICDNQVSTGDTRIFFVNPA
Sbjct: 61 QHTYSCKVRVWRYLKGKDLVARESLLDGGNKVVISGFGDPLICDNQVSTGDTRIFFVNPA 120
Query: 121 PPYLWPAHKNELMLNSSLMRITLRNLEEVEFCVEDKPGTHFTPVPPTPPDACRGMLCGFG 180
PPYLWPAHKNELMLNSSLMRITLRNLEEVEFCVEDKPGTHFTPVPPTPPDACRGMLCGFG
Sbjct: 121 PPYLWPAHKNELMLNSSLMRITLRNLEEVEFCVEDKPGTHFTPVPPTPPDACRGMLCGFG 180
Query: 181 AVCEPNAEGPGRASCVCKKSPCPSVVAPVCGSDASTYSNECELQRAQCSQQRRIRLLSRG 240
AVCEPNAEGPGRASCVCKKSPCPSVVAPVCGSDASTYSNECELQRAQCSQQRRIRLLSRG
Sbjct: 181 AVCEPNAEGPGRASCVCKKSPCPSVVAPVCGSDASTYSNECELQRAQCSQQRRIRLLSRG 240
Query: 241 PCGSRDPCSNVTCSFGSTCARSADGLTASCLCPATCRGAPEGTVCGSDGADYPGECQLLR 300
PCGSRDPCSNVTCSFGSTCARSADGLTASCLCPATCRGAPEGTVCGSDGADYPGECQLLR
Sbjct: 241 PCGSRDPCSNVTCSFGSTCARSADGLTASCLCPATCRGAPEGTVCGSDGADYPGECQLLR 300
Query: 301 RACARQENVFKKFDGPCDPCQGALPDPSRSCRVNPRTRRPEMLLRPESCPARQAPVCGDD 360
RACARQENVFKKFDGPCDPCQGALPDPSRSCRVNPRTRRPEMLLRPESCPARQAPVCGDD
Sbjct: 301 RACARQENVFKKFDGPCDPCQGALPDPSRSCRVNPRTRRPEMLLRPESCPARQAPVCGDD 360
Query: 361 GVTYENDCVMGRSGAARGLLLQKVRSGQCQGRDQCPEPCRFNAVCLSRRGRPRCSCDRVT 420
GVTYENDCVMGRSGAARGLLLQKVRSGQCQGRDQCPEPCRFNAVCLSRRGRPRCSCDRVT
Sbjct: 361 GVTYENDCVMGRSGAARGLLLQKVRSGQCQGRDQCPEPCRFNAVCLSRRGRPRCSCDRVT 420
Query: 421 CDGAYRPVCAQDGRTYDSDCWRQQAECRQQRAIPSKHQGPCDQAPSPCLGVQCAFGATCA 480
CDGAYRPVCAQDGRTYDSDCWRQQAECRQQRAIPSKHQGPCDQAPSPCLGVQCAFGATCA
Sbjct: 421 CDGAYRPVCAQDGRTYDSDCWRQQAECRQQRAIPSKHQGPCDQAPSPCLGVQCAFGATCA 480
Query: 481 VKNGQAACECLQACSSLYDPVCGSDGVTYGSACELEATACTLGREIQVARKGPCDRCGQC 540
VKNGQAACECLQACSSLYDPVCGSDGVTYGSACELEATACTLGREIQVARKGPCDRCGQC
Sbjct: 481 VKNGQAACECLQACSSLYDPVCGSDGVTYGSACELEATACTLGREIQVARKGPCDRCGQC 540
Query: 541 RFGALCEAETGRCVCPSECVALAQPVCGSDGHTYPSECMLHVHACTHQISLHVASAGPCE 600
RFGALCEAETGRCVCPSECVALAQPVCGSDGHTYPSECMLHVHACTHQISLHVASAGPCE
Sbjct: 541 RFGALCEAETGRCVCPSECVALAQPVCGSDGHTYPSECMLHVHACTHQISLHVASAGPCE 600
Query: 601 TCGDAVCAFGAVCSAGQCVCPRCEHPPPGPVCGSDGVTYGSACELREAACLQQTQIEEAR 660
TCGDAVCAFGAVCSAGQCVCPRCEHPPPGPVCGSDGVTYGSACELREAACLQQTQIEEAR
Sbjct: 601 TCGDAVCAFGAVCSAGQCVCPRCEHPPPGPVCGSDGVTYGSACELREAACLQQTQIEEAR 660
Query: 661 AGPCEQAECGSGGSGSGEDGDCEQELCRQRGGIWDEDSEDGPCVCDFSCQSVPGSPVCGS 720
AGPCEQAECGSGGSGSGEDGDCEQELCRQRGGIWDEDSEDGPCVCDFSCQSVPGSPVCGS
Sbjct: 661 AGPCEQAECGSGGSGSGEDGDCEQELCRQRGGIWDEDSEDGPCVCDFSCQSVPGSPVCGS 720
Query: 721 DGVTYSTECELKKARCESQRGLYVAAQGACRGPTFAPLPPVAPLHCAQTPYGCCQDNITA 780
DGVTYSTECELKKARCESQRGLYVAAQGACRGPTFAPLPPVAPLHCAQTPYGCCQDNITA
Sbjct: 721 DGVTYSTECELKKARCESQRGLYVAAQGACRGPTFAPLPPVAPLHCAQTPYGCCQDNITA 780
Query: 781 ARGVGLAGCPSACQCNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDG 840
ARGVGLAGCPSACQCNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDG
Sbjct: 781 ARGVGLAGCPSACQCNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDG 840
Query: 841 RSGCTPCSCDPQGAVRDDCEQMTGLCSCKPGVAGPKCGQCPDGRALGPAGCEADASAPAT 900
RSGCTPCSCDPQGAVRDDCEQMTGLCSCKPGVAGPKCGQCPDGRALGPAGCEADASAPAT
Sbjct: 841 RSGCTPCSCDPQGAVRDDCEQMTGLCSCKPGVAGPKCGQCPDGRALGPAGCEADASAPAT 900
Query: 901 CAEMRCEFGARCVEESGSAHCVCPMLTCPEANATKVCGSDGVTYGNECQLKTIACRQGLQ 960
CAEMRCEFGARCVEESGSAHCVCPMLTCPEANATKVCGSDGVTYGNECQLKTIACRQGLQ
Sbjct: 901 CAEMRCEFGARCVEESGSAHCVCPMLTCPEANATKVCGSDGVTYGNECQLKTIACRQGLQ 960
Query: 961 ISIQSLGPCQEAVAPSTHPTSASVTVTTPGLLLSQALPAPPGALPLAPSSTAHSQTTPPP 1020
ISIQSLGPCQEAVAPSTHPTSASVTVTTPGLLLSQALPAPPGALPLAPSSTAHSQTTPPP
Sbjct: 961 ISIQSLGPCQEAVAPSTHPTSASVTVTTPGLLLSQALPAPPGALPLAPSSTAHSQTTPPP 1020
Query: 1021 SSRPRTTASVPRTTVWPVLTVPPTAPSPAPSLVASAFGESGSTDGSSDEELSGDQEASGG 1080
SSRPRTTASVPRTTVWPVLTVPPTAPSPAPSLVASAFGESGSTDGSSDEELSGDQEASGG
Sbjct: 1021 SSRPRTTASVPRTTVWPVLTVPPTAPSPAPSLVASAFGESGSTDGSSDEELSGDQEASGG 1080
Query: 1081 GSGGLEPLEGSSVATPGPPVERASCYNSALGCCSDGKTPSLDAEGSNCPATKVFQGVLEL 1140
GSGGLEPLEGSSVATPGPPVERASCYNSALGCCSDGKTPSLDAEGSNCPATKVFQGVLEL
Sbjct: 1081 GSGGLEPLEGSSVATPGPPVERASCYNSALGCCSDGKTPSLDAEGSNCPATKVFQGVLEL 1140
Query: 1141 EGVEGQELFYTPEMADPKSELFGETARSIESTLDDLFRNSDVKKDFRSVRLRDLGPGKSV 1200
EGVEGQELFYTPEMADPKSELFGETARSIESTLDDLFRNSDVKKDFRSVRLRDLGPGKSV
Sbjct: 1141 EGVEGQELFYTPEMADPKSELFGETARSIESTLDDLFRNSDVKKDFRSVRLRDLGPGKSV 1200
Query: 1201 RAIVDVHFDPTTAFRAPDVARALLRQIQVSRRRSLGVRRPLQEHVRFMDFDWFPAFITGA 1260
RAIVDVHFDPTTAFRAPDVARALLRQIQVSRRRSLGVRRPLQEHVRFMDFDWFPAFITGA
Sbjct: 1201 RAIVDVHFDPTTAFRAPDVARALLRQIQVSRRRSLGVRRPLQEHVRFMDFDWFPAFITGA 1260
Query: 1261 TSGAIAAGATARATTASRLPSSAVTPRAPHPSHTSQPVAKTTAAPTTRRPPTTAPSRVPG 1320
TSGAIAAGATARATTASRLPSSAVTPRAPHPSHTSQPVAKTTAAPTTRRPPTTAPSRVPG
Sbjct: 1261 TSGAIAAGATARATTASRLPSSAVTPRAPHPSHTSQPVAKTTAAPTTRRPPTTAPSRVPG 1320
Query: 1321 RRPPAPQQPPKPCDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEKVLGAPVPAFEGR 1380
RRPPAPQQPPKPCDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEKVLGAPVPAFEGR
Sbjct: 1321 RRPPAPQQPPKPCDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEKVLGAPVPAFEGR 1380
Query: 1381 SFLAFPTLRAYHTLRLALEFRALEPQGLLLYNGNARGKDFLALALLDGRVQLRFDTGSGP 1440
SFLAFPTLRAYHTLRLALEFRALEPQGLLLYNGNARGKDFLALALLDGRVQLRFDTGSGP
Sbjct: 1381 SFLAFPTLRAYHTLRLALEFRALEPQGLLLYNGNARGKDFLALALLDGRVQLRFDTGSGP 1440
Query: 1441 AVLTSAVPVEPGQWHRLELSRHWRRGTLSVDGETPVLGESPSGTDGLNLDTDLFVGGVPE 1500
AVLTSAVPVEPGQWHRLELSRHWRRGTLSVDGETPVLGESPSGTDGLNLDTDLFVGGVPE
Sbjct: 1441 AVLTSAVPVEPGQWHRLELSRHWRRGTLSVDGETPVLGESPSGTDGLNLDTDLFVGGVPE 1500
Query: 1501 DQAAVALERTFVGAGLRGCIRLLDVNNQRLELGIGPGAATRGSGVGECGDHPCLPNPCHG 1560
DQAAVALERTFVGAGLRGCIRLLDVNNQRLELGIGPGAATRGSGVGECGDHPCLPNPCHG
Sbjct: 1501 DQAAVALERTFVGAGLRGCIRLLDVNNQRLELGIGPGAATRGSGVGECGDHPCLPNPCHG 1560
Query: 1561 GAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQCECPLGRE 1620
GAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQCECPLGRE
Sbjct: 1561 GAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQCECPLGRE 1620
Query: 1621 GTFCQTASGQDGSGPFLADFNGFSHLELRGLHTFARDLGEKMALEVVFLARGPSGLLLYN 1680
GTFCQTASGQDGSGPFLADFNGFSHLELRGLHTFARDLGEKMALEVVFLARGPSGLLLYN
Sbjct: 1621 GTFCQTASGQDGSGPFLADFNGFSHLELRGLHTFARDLGEKMALEVVFLARGPSGLLLYN 1680
Query: 1681 GQKTDGKGDFVSLALRDRRLEFRYDLGKGAAVIRSREPVTLGAWTRVSLERNGRKGALRV 1740
GQKTDGKGDFVSLALRDRRLEFRYDLGKGAAVIRSREPVTLGAWTRVSLERNGRKGALRV
Sbjct: 1681 GQKTDGKGDFVSLALRDRRLEFRYDLGKGAAVIRSREPVTLGAWTRVSLERNGRKGALRV 1740
Query: 1741 GDGPRVLGESPVPHTVLNLKEPLYVGGAPDFSKLARAAAVSSGFDGAIQLVSLGGRQLLT 1800
GDGPRVLGESPVPHTVLNLKEPLYVGGAPDFSKLARAAAVSSGFDGAIQLVSLGGRQLLT
Sbjct: 1741 GDGPRVLGESPVPHTVLNLKEPLYVGGAPDFSKLARAAAVSSGFDGAIQLVSLGGRQLLT 1800
Query: 1801 PEHVLRQVDVTSFAGHPCTRASGHPCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVEKS 1860
PEHVLRQVDVTSFAGHPCTRASGHPCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVEKS
Sbjct: 1801 PEHVLRQVDVTSFAGHPCTRASGHPCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVEKS 1860
Query: 1861 AGDVDTLAFDGRTFVEYLNAVTESEKALQSNHFELSLRTEATQGLVLWSGKATERADYVA 1920
AGDVDTLAFDGRTFVEYLNAVTESEKALQSNHFELSLRTEATQGLVLWSGKATERADYVA
Sbjct: 1861 AGDVDTLAFDGRTFVEYLNAVTESEKALQSNHFELSLRTEATQGLVLWSGKATERADYVA 1920
Query: 1921 LAIVDGHLQLSYNLGSQPVVLRSTVPVNTNRWLRVVAHREQREGSLQVGNEAPVTGSSPL 1980
LAIVDGHLQLSYNLGSQPVVLRSTVPVNTNRWLRVVAHREQREGSLQVGNEAPVTGSSPL
Sbjct: 1921 LAIVDGHLQLSYNLGSQPVVLRSTVPVNTNRWLRVVAHREQREGSLQVGNEAPVTGSSPL 1980
Query: 1981 GATQLDTDGALWLGGLPELPVGPALPKAYGTGFVGCLRDVVVGRHPLHLLEDAVTKPELR 2040
GATQLDTDGALWLGGLPELPVGPALPKAYGTGFVGCLRDVVVGRHPLHLLEDAVTKPELR
Sbjct: 1981 GATQLDTDGALWLGGLPELPVGPALPKAYGTGFVGCLRDVVVGRHPLHLLEDAVTKPELR 2040
Query: 2041 PCPTP 2045
PCPTP
Sbjct: 2041 PCPTP 2045
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 330 bits (845), Expect = 1e-89
Identities = 254/790 (32%), Positives = 352/790 (44%), Gaps = 131/790 (16%)
Query: 1351 GGFTCSCPAGRGGAVCEKVLGAP---VPAFEGR--SFLAFPTLR-AYHTLRLALEFRALE 1404
G + C+ +G L P VP F SFL PT++ AY + + FR
Sbjct: 3637 GTYVCTATNRQGKVKAFAHLQVPERVVPYFTQTPYSFLPLPTIKDAYRKFEIKITFRPDS 3696
Query: 1405 PQGLLLYNGNAR-----------GKDFLALALLDGRVQLRFDTGSGPAVLTSAVPVEPGQ 1453
G+LLYNG R DF++ L+ GR + RFD GSG A + P+ G
Sbjct: 3697 ADGMLLYNGQKRVPGSPTNLANRQPDFISFGLVGGRPEFRFDAGSGMATIRHPTPLALGH 3756
Query: 1454 WHRLELSRHWRRGTLSVDGETPVLGESPSGTDGLNLDTDLFVGGVPEDQAAVALERTFVG 1513
+H + L R +G+L V PV G S GL+L+ +L++GG P+ A + + +
Sbjct: 3757 FHTVTLLRSLTQGSLIVGDLAPVNGTSQGKFQGLDLNEELYLGGYPDYGA---IPKAGLS 3813
Query: 1514 AGLRGCIRLLDVNNQRLELGIGPGAATRGSGVGECGDHPCLPNPCHGGAPCQNLEAGRFH 1573
+G GC+R L + + + + G+ C C PC G C + E+ +
Sbjct: 3814 SGFIGCVRELRIQGEEI---VFHDLNLTAHGISHCPT--CRDRPCQNGGQCHDSESSSYV 3868
Query: 1574 CQCPPGRVGPTCADEKS-PCQPNPCHGAAPCRVLPEG-GAQCECPLGREGTFCQ-----T 1626
C CP G G C ++ C P C A C P+G G C C LGR G C+ T
Sbjct: 3869 CVCPAGFTGSRCEHSQALHCHPEACGPDATCVNRPDGRGYTCRCHLGRSGLRCEEGVTVT 3928
Query: 1627 ASGQDGSGPFLA-DFNGFSHLELRGLHTFARDLGEKMALEVVFLARGPSGLLLYNGQKTD 1685
G+G +LA +H ELR L+V F P G+LL++G K+
Sbjct: 3929 TPSLSGAGSYLALPALTNTHHELR--------------LDVEFKPLAPDGVLLFSGGKSG 3974
Query: 1686 GKGDFVSLALRDRRLEFRYDLGKGAAVIRSREPVTLGAWTRVSLERNGRKGALRVGDGPR 1745
DFVSLA+ LEFRY+LG G AV+RS EP+ LG W RVS ER + G+LRV G
Sbjct: 3975 PVEDFVSLAMVGGHLEFRYELGSGLAVLRSAEPLALGRWHRVSAERLNKDGSLRVNGGRP 4034
Query: 1746 VLGESPVPHTVLNLKEPLYVGGAPDFSKLARAAAVSSGFDGAIQLVSLGGRQL-LTPEHV 1804
VL SP LNL LY+GG L+ A +S+ F G + VS+ G++L LT +
Sbjct: 4035 VLRSSPGKSQGLNLHTLLYLGGVEPSVPLSPATNMSAHFRGCVGEVSVNGKRLDLTYSFL 4094
Query: 1805 LRQVDVTSFAGHPCTRASGHPCLNGASCVP----------------------------RE 1836
Q + PC R PC +GA+C+P RE
Sbjct: 4095 GSQGIGQCYDSSPCER---QPCQHGATCMPAGEYEFQCLCRDGFKGDLCEHEENPCQLRE 4151
Query: 1837 AAY--------VCLCPGGFSGPHCEKGL----------VEKSAG------------DVDT 1866
CLC GFSGP C++G +E S G D
Sbjct: 4152 PCLHGGTCQGTRCLCLPGFSGPRCQQGSGHGIAESDWHLEGSGGNDAPGQYGAYFHDDGF 4211
Query: 1867 LAFDGRTFVEYLNAVTESEKALQSNHFELSLRTEATQGLVLWS----GKATERADYVALA 1922
LAF G F L V E+ EL +RT GL+LW G+A + D+++L
Sbjct: 4212 LAFPGHVFSRSLPEVPET--------IELEVRTSTASGLLLWQGVEVGEAGQGKDFISLG 4263
Query: 1923 IVDGHLQLSYNLGSQPVVLRSTVPVNTNRWLRVVAHREQREGSLQVGNEAPVTGSSPLGA 1982
+ DGHL Y LGS L S P+N W RV A RE R GS+QV E V+G SP
Sbjct: 4264 LQDGHLVFRYQLGSGEARLVSEDPINDGEWHRVTALREGRRGSIQVDGEELVSGRSPGPN 4323
Query: 1983 TQLDTDGALWLGGLPELPVGPALPKAYGTGFVGCLRDVVVGR--------HPLHLLEDAV 2034
++ G++++GG P+ V + +G GC++++V+ PL L A
Sbjct: 4324 VAVNAKGSVYIGGAPD--VATLTGGRFSSGITGCVKNLVLHSARPGAPPPQPLDLQHRAQ 4381
Query: 2035 TKPELRPCPT 2044
RPCP+
Sbjct: 4382 AGANTRPCPS 4391
Score = 276 bits (707), Expect = 1e-73
Identities = 179/483 (37%), Positives = 248/483 (51%), Gaps = 39/483 (8%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEKVLGAPVPAFEGR-SFLAFPTL-RA 1390
C + C TC + G G+TC C GR G CE+ + P+ G S+LA P L
Sbjct: 3888 CHPEACGPDATCVNRPDGRGYTCRCHLGRSGLRCEEGVTVTTPSLSGAGSYLALPALTNT 3947
Query: 1391 YHTLRLALEFRALEPQGLLLYNGNARG--KDFLALALLDGRVQLRFDTGSGPAVLTSAVP 1448
+H LRL +EF+ L P G+LL++G G +DF++LA++ G ++ R++ GSG AVL SA P
Sbjct: 3948 HHELRLDVEFKPLAPDGVLLFSGGKSGPVEDFVSLAMVGGHLEFRYELGSGLAVLRSAEP 4007
Query: 1449 VEPGQWHRLELSRHWRRGTLSVDGETPVLGESPSGTDGLNLDTDLFVGGVPEDQAAVALE 1508
+ G+WHR+ R + G+L V+G PVL SP + GLNL T L++GGV + +V L
Sbjct: 4008 LALGRWHRVSAERLNKDGSLRVNGGRPVLRSSPGKSQGLNLHTLLYLGGV---EPSVPLS 4064
Query: 1509 -RTFVGAGLRGCIRLLDVNNQRLELGIGPGAATRGSGVGECGDH-PCLPNPCHGGAPCQN 1566
T + A RGC+ + VN +RL+L + G+G+C D PC PC GA C
Sbjct: 4065 PATNMSAHFRGCVGEVSVNGKRLDLTY---SFLGSQGIGQCYDSSPCERQPCQHGATCMP 4121
Query: 1567 LEAGRFHCQCPPGRVGPTCADEKSPCQ-PNPCHGAAPCRVLPEGGAQCECPLGREGTFCQ 1625
F C C G G C E++PCQ PC C+ G +C C G G CQ
Sbjct: 4122 AGEYEFQCLCRDGFKGDLCEHEENPCQLREPCLHGGTCQ-----GTRCLCLPGFSGPRCQ 4176
Query: 1626 TASGQ---------------DGSGPFLADFNGFSHLELRGLHTFARDLGE-KMALEVVFL 1669
SG D G + A F+ L G H F+R L E +E+
Sbjct: 4177 QGSGHGIAESDWHLEGSGGNDAPGQYGAYFHDDGFLAFPG-HVFSRSLPEVPETIELEVR 4235
Query: 1670 ARGPSGLLLYNGQKTDGKG---DFVSLALRDRRLEFRYDLGKGAAVIRSREPVTLGAWTR 1726
SGLLL+ G + G DF+SL L+D L FRY LG G A + S +P+ G W R
Sbjct: 4236 TSTASGLLLWQGVEVGEAGQGKDFISLGLQDGHLVFRYQLGSGEARLVSEDPINDGEWHR 4295
Query: 1727 VSLERNGRKGALRVGDGPRVLGESPVPHTVLNLKEPLYVGGAPDFSKLARAAAVSSGFDG 1786
V+ R GR+G+++V V G SP P+ +N K +Y+GGAPD + L SSG G
Sbjct: 4296 VTALREGRRGSIQVDGEELVSGRSPGPNVAVNAKGSVYIGGAPDVATLT-GGRFSSGITG 4354
Query: 1787 AIQ 1789
++
Sbjct: 4355 CVK 4357
Score = 65.5 bits (158), Expect = 5e-10
Identities = 70/271 (25%), Positives = 88/271 (32%), Gaps = 65/271 (23%)
Query: 676 SGEDGDCEQELCRQRGGIWDEDSEDGPCVCDFSCQSVPGSPVCGSDGVTYSTECELKKAR 735
+G+D E E C G +D CD P G+ C
Sbjct: 1115 TGQDPALEVEQCSCPPGYRGPSCQD----CDTGYTRTPSGLYLGT---CERCSCHGHSEA 1167
Query: 736 CESQRGLYVAAQGACRGPTFAPLPPVAPLHCAQTPYGCCQDNITAARGVGLAGCPSACQC 795
CE + G Q GP C YG Q G P CQ
Sbjct: 1168 CEPETGACQGCQHHTEGPRCE--------QCQPGYYGDAQ-----------RGTPQDCQL 1208
Query: 796 NPHGSYGGTCDPATGQCS---------------CRPGVGGLRCDRCEPGFWNFRGIVTDG 840
P YG DPA GQ + C PG G C+RC PG++ G + G
Sbjct: 1209 CP--CYG---DPAAGQAAHTCFLDTDGHPTCDACSPGHSGRHCERCAPGYY---GNPSQG 1260
Query: 841 R--------SGCTPCSCDPQGAVRDDCEQMTGLCSCKPGVAGPKCGQCPDGRALGPAGCE 892
+ G C+CDPQG+V C+ G C CK V G C C P
Sbjct: 1261 QPCQRDSQVPGPIGCNCDPQGSVSSQCD-AAGQCQCKAQVEGLTCSHC------RPHHFH 1313
Query: 893 ADASAPATCAEMRC-EFGARCVEESGSAHCV 922
AS P C C +C + + H +
Sbjct: 1314 LSASNPDGCLPCFCMGITQQCASSAYTRHLI 1344
Score = 65.1 bits (157), Expect = 7e-10
Identities = 67/245 (27%), Positives = 93/245 (37%), Gaps = 39/245 (15%)
Query: 774 CQDNITAARGVGLAGCPSACQCNPHGSYGGTCDPATGQC-SCRPGVGGLRCDRCEPGFWN 832
C + T G G S C CN H S +CDP G C +C+ G +C++C+ GF
Sbjct: 745 CDAHFTRVPGGPYLGTCSGCNCNGHAS---SCDPVYGHCLNCQHNTEGPQCNKCKAGF-- 799
Query: 833 FRGIVTDGRSGCTPCSC---DPQGAVRDDCEQMT---GLC-SCKPGVAGPKCGQCP---D 882
F + + C PC C D D C T C +C PG G +C C +
Sbjct: 800 FGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPGYTGRRCESCAPGYE 859
Query: 883 GRALGPAG-----------CEADASAPATCAEMRCE---FGARCVE-ESGSAHCVCPMLT 927
G + P G C+ S + RC+ G C E GS H L+
Sbjct: 860 GNPIQPGGKCRPVNQEIVRCDERGSMGTSGEACRCKNNVVGRLCNECADGSFH-----LS 914
Query: 928 CPEANATKVCGSDGVTYGNECQLKTIACRQGLQISIQSLGPCQEAVAPSTHPTSASVTVT 987
+ C GV+ C + + R L + + G A STH T+ +
Sbjct: 915 TRNPDGCLKCFCMGVS--RHCTSSSWS-RAQLHGASEEPGHFSLTNAASTHTTNEGIFSP 971
Query: 988 TPGLL 992
TPG L
Sbjct: 972 TPGEL 976
Score = 60.8 bits (146), Expect = 1e-08
Identities = 39/126 (30%), Positives = 52/126 (41%), Gaps = 16/126 (12%)
Query: 773 CCQDNITAARGVGLAGCPSACQCNPHGSYGGTCDPATGQCS-CRPGVGGLRCDRCEPGFW 831
C G+ L C C+CN H C P TG CS C+ G C+ C PG++
Sbjct: 1544 CAPGYTRTGSGLYLGHC-ELCECNGHSDL---CHPETGACSQCQHNAAGEFCELCAPGYY 1599
Query: 832 NFRGIVTDGR-SGCTPCSC---DPQGAVRDDCEQMTG----LCSCKPGVAGPKCGQCPDG 883
G T G C PC+C +P+ CE + +C+PG G C QC G
Sbjct: 1600 ---GDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGYTGQYCEQCGPG 1656
Query: 884 RALGPA 889
P+
Sbjct: 1657 YVGNPS 1662
Score = 49.3 bits (116), Expect = 4e-05
Identities = 53/206 (25%), Positives = 68/206 (33%), Gaps = 48/206 (23%)
Query: 705 CDFSCQSVPGSPVCGSDGVTYSTECELKKARCESQRGLYVAAQGACRGPTFAPLPPVAPL 764
CD VPG P G+ C + C+ G + Q GP
Sbjct: 745 CDAHFTRVPGGPYLGTCS---GCNCNGHASSCDPVYGHCLNCQHNTEGP----------- 790
Query: 765 HCAQTPYGCCQDNITA-ARGVGLAGCP---------SACQCNPHGSYGGTCDPATGQCSC 814
C + G D + A A CP C + G TCD +C
Sbjct: 791 QCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQ--ATCD------AC 842
Query: 815 RPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCS-----CDPQGAVRDDCEQMTGLCSCK 869
PG G RC+ C PG + G C P + CD +G++ E C CK
Sbjct: 843 APGYTGRRCESCAPG---YEGNPIQPGGKCRPVNQEIVRCDERGSMGTSGE----ACRCK 895
Query: 870 PGVAGPKCGQCPDG----RALGPAGC 891
V G C +C DG P GC
Sbjct: 896 NNVVGRLCNECADGSFHLSTRNPDGC 921
Score = 48.5 bits (114), Expect = 7e-05
Identities = 45/149 (30%), Positives = 53/149 (35%), Gaps = 34/149 (22%)
Query: 811 QCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDPQGAVRDDCEQMTGLCS-CK 869
+C C PG GL C C PG+ + G C C C+ D C TG CS C+
Sbjct: 1529 ECRCPPGYIGLSCQDCAPGYTRTGSGLYLGH--CELCECNGHS---DLCHPETGACSQCQ 1583
Query: 870 PGVAGPKCGQCPDGRALGPAGCEADASAPATCAEMRCEFGARCVEESGSAHCVCPMLTCP 929
AG C C G +A A P C C CP LT P
Sbjct: 1584 HNAAGEFCELCAPGYY-----GDATAGTPEDCQP-----------------CACP-LTNP 1620
Query: 930 EANATKVCGSDGVTYGNECQLKTIACRQG 958
E ++ C S G G C AC G
Sbjct: 1621 ENMFSRTCESLGAG-GYRC----TACEPG 1644
Score = 46.2 bits (108), Expect = 3e-04
Identities = 35/106 (33%), Positives = 42/106 (39%), Gaps = 16/106 (15%)
Query: 1536 PGAATRGSGVG-------ECGDHPCLPNPCHGG-APCQNLEAGRFHCQCPPGRVGPTCAD 1587
PG GSG+ EC H L +P G + CQ+ AG F C PG G A
Sbjct: 1546 PGYTRTGSGLYLGHCELCECNGHSDLCHPETGACSQCQHNAAGEFCELCAPGYYGDATAG 1605
Query: 1588 EKSPCQPNPCHGAAP-------CRVLPEGGAQC-ECPLGREGTFCQ 1625
CQP C P C L GG +C C G G +C+
Sbjct: 1606 TPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGYTGQYCE 1651
Score = 44.3 bits (103), Expect = 0.001
Identities = 30/115 (26%), Positives = 47/115 (40%), Gaps = 9/115 (7%)
Query: 811 QCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDPQGAVRDDCEQMTGLC-SCK 869
+C C G GL C+ C+ F G G C+ C+C+ + C+ + G C +C+
Sbjct: 730 ECRCPIGYSGLSCESCDAHFTRVPGGPYLGT--CSGCNCNGHAS---SCDPVYGHCLNCQ 784
Query: 870 PGVAGPKCGQCPDGRALGPAGCEADASAPATC--AEMRCEFGARC-VEESGSAHC 921
GP+C +C G A + P C + F C ++ G A C
Sbjct: 785 HNTEGPQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATC 839
Score = 38.5 bits (88), Expect = 0.068
Identities = 40/143 (27%), Positives = 45/143 (31%), Gaps = 33/143 (23%)
Query: 696 EDSEDGPCVCDFSCQS-VPGSPVCGSDGVTYSTECELKKARCESQRGLYVAAQGACRGPT 754
E+ P SCQ PG GS Y CEL C L GAC
Sbjct: 1528 EECRCPPGYIGLSCQDCAPGYTRTGSG--LYLGHCEL--CECNGHSDLCHPETGACS--- 1580
Query: 755 FAPLPPVAPLHCAQTPYG-CCQDNITAARGVGLAGCPSACQ------CNPHGSYGGTCDP 807
C G C+ G AG P CQ NP + TC+
Sbjct: 1581 ----------QCQHNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCES 1630
Query: 808 ATGQCSCRPGVGGLRCDRCEPGF 830
G GG RC CEPG+
Sbjct: 1631 L--------GAGGYRCTACEPGY 1645
Score = 36.6 bits (83), Expect = 0.26
Identities = 29/102 (28%), Positives = 38/102 (37%), Gaps = 23/102 (22%)
Query: 781 ARGVGLAGCPSACQCNPHGSYGGTCDPATG---QCSCRPGVGGLRCDRCEPGFWNFRGIV 837
++G+G S C+ P +G TC PA QC CR G G C+ E
Sbjct: 4096 SQGIGQCYDSSPCERQPC-QHGATCMPAGEYEFQCLCRDGFKGDLCEHEE---------- 4144
Query: 838 TDGRSGCTPCSCDPQGAVRDDCEQMTGLCSCKPGVAGPKCGQ 879
PC C+ C C PG +GP+C Q
Sbjct: 4145 -------NPCQLREPCLHGGTCQGTR--CLCLPGFSGPRCQQ 4177
Score = 35.8 bits (81), Expect = 0.44
Identities = 43/158 (27%), Positives = 58/158 (36%), Gaps = 24/158 (15%)
Query: 1482 SGTDGLNLDTDLFVGGVPEDQA---AVALERTFVGAGLRG-CIRLLDVNNQRLELGIGPG 1537
S G+++D VPE+ A+ +E+ G RG + D R G+ G
Sbjct: 1100 SRVSGISMDV-----AVPEETGQDPALEVEQCSCPPGYRGPSCQDCDTGYTRTPSGLYLG 1154
Query: 1538 AATRGSGVGECGDHPCLPNP--CHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPN 1595
R S G C P C G CQ+ G QC PG G CQ
Sbjct: 1155 TCERCSCHGH--SEACEPETGACQG---CQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLC 1209
Query: 1596 PCHG-------AAPCRVLPEGGAQCE-CPLGREGTFCQ 1625
PC+G A C + +G C+ C G G C+
Sbjct: 1210 PCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHSGRHCE 1247
Score = 35.4 bits (80), Expect = 0.58
Identities = 17/36 (47%), Positives = 19/36 (52%), Gaps = 1/36 (2%)
Query: 1332 PCDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCE 1367
PC+ QPC HG TC A F C C G G +CE
Sbjct: 4107 PCERQPCQHGATCMP-AGEYEFQCLCRDGFKGDLCE 4141
Score = 33.1 bits (74), Expect = 2.9
Identities = 33/137 (24%), Positives = 43/137 (31%), Gaps = 30/137 (21%)
Query: 509 YGSACELEATACTLGREIQVARKGPCDRCGQCRFGALCEAETGRCVCPSECVALAQPVCG 568
+ ACE E AC + Q +GP RC QC+ G +A+ G C P G
Sbjct: 1164 HSEACEPETGAC---QGCQHHTEGP--RCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAG 1218
Query: 569 SDGHT--------------YPSECMLHVHACTHQISLHVASAGPCETCGDAVCAFGAVC- 613
HT P H C + + PC+ G C
Sbjct: 1219 QAAHTCFLDTDGHPTCDACSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCD 1278
Query: 614 ----------SAGQCVC 620
+AGQC C
Sbjct: 1279 PQGSVSSQCDAAGQCQC 1295
Score = 33.1 bits (74), Expect = 2.9
Identities = 20/65 (30%), Positives = 28/65 (43%), Gaps = 15/65 (23%)
Query: 1574 CQCPPGRVGPTCAD------------EKSPCQPNPCHGAAP-CRVLPEGGAQCECPLGRE 1620
C+CPPG +G +C D C+ C+G + C PE GA +C
Sbjct: 1530 CRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDLCH--PETGACSQCQHNAA 1587
Query: 1621 GTFCQ 1625
G FC+
Sbjct: 1588 GEFCE 1592
Score = 32.3 bits (72), Expect = 4.9
Identities = 18/50 (36%), Positives = 21/50 (42%), Gaps = 11/50 (22%)
Query: 587 HQISLHVASAGPCETCGDAVCAFGAVC-----SAGQCVCP------RCEH 625
H ++L C TC D C G C S+ CVCP RCEH
Sbjct: 3833 HDLNLTAHGISHCPTCRDRPCQNGGQCHDSESSSYVCVCPAGFTGSRCEH 3882
Score = 31.6 bits (70), Expect = 8.3
Identities = 29/109 (26%), Positives = 44/109 (40%), Gaps = 11/109 (10%)
Query: 1536 PGAATRGSGVG-ECGDHPCLPNPCHGGA-PCQNLEAGRFHCQCPPGRVGPTCADEKSPCQ 1593
PG G+ G C H +P +G CQ+ G +C G G + C+
Sbjct: 753 PGGPYLGTCSGCNCNGHASSCDPVYGHCLNCQHNTEGPQCNKCKAGFFGDAMKATATSCR 812
Query: 1594 PNPC-------HGAAPCRVLPEGGAQCE-CPLGREGTFCQT-ASGQDGS 1633
P PC + C + +G A C+ C G G C++ A G +G+
Sbjct: 813 PCPCPYIDASRRFSDTCFLDTDGQATCDACAPGYTGRRCESCAPGYEGN 861
>gi|33469931 EGF-like, fibronectin type III and laminin G domains
isoform 2 [Homo sapiens]
Length = 775
Score = 328 bits (840), Expect = 4e-89
Identities = 234/769 (30%), Positives = 355/769 (46%), Gaps = 79/769 (10%)
Query: 1290 HPSHTSQPVAKTTAA-PTTRRPPTTAPSRVPGRRPPAPQQP--PKPCDSQPCFHGGTCQD 1346
+P S+ + T+A+ P T P P + G+ A PCD C C +
Sbjct: 67 NPKTISRLIPPTSASLPVTTVAPQPIPIQRKGKNGVAIMSRLFDMPCDETLCSADSFCVN 126
Query: 1347 WALGGGFTCSCPAGRGGAVCEKVLGAPVPAFEGRSFLAFPTLR-AYHTLRLALEFRALEP 1405
GG C C G+GG C + + P F G S++ F L+ +Y ++ LEFRA
Sbjct: 127 DYTWGGSRCQCTLGKGGESCSEDIVIQYPQFFGHSYVTFEPLKNSYQAFQITLEFRAEAE 186
Query: 1406 QGLLLYNG-NARGK-DFLALALLDGRVQLRFDTGSGPAVLTSAVPVEPGQWHRLELSRHW 1463
GLLLY G N G+ DF++LA++ +Q RF+ G+G A++ S ++ G WH + L R
Sbjct: 187 DGLLLYCGENEHGRGDFMSLAIIRRSLQFRFNCGTGVAIIVSETKIKLGGWHTVMLYRDG 246
Query: 1464 RRGTLSVDGETPVLGESPSGTDGLNLDTDLFVGGVPEDQAAVALERTFVGAGLRGCIRLL 1523
G L ++ TPV G+S + T L++GG P A + T G +GC++ L
Sbjct: 247 LNGLLQLNNGTPVTGQSQGQYSKITFRTPLYLGGAPS--AYWLVRATGTNRGFQGCVQSL 304
Query: 1524 DVNNQRLELGIGP-GAATRGSGVGECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVG 1582
VN +R+++ P G A G+ VGEC C C G C ++A +
Sbjct: 305 AVNGRRIDMRPWPLGKALSGADVGECSSGICDEASCIHGGTCTAIKADSYI--------- 355
Query: 1583 PTCADEKSPCQPNPCHGAAPCRVLPEGGAQCECPLGREGTFCQTASGQDGSGPFLADFNG 1642
C CPLG +G C+ A F
Sbjct: 356 ------------------------------CLCPLGFKGRHCEDA--------FTLTIPQ 377
Query: 1643 FSHLELRGLHTFARDLGEK-----MALEVVFLARGPSGLLLYNGQKTDGKGDFVSLALRD 1697
F LR L + M E+ F G+LLY+ G DF+S+ L
Sbjct: 378 FRE-SLRSYAATPWPLEPQHYLSFMEFEITFRPDSGDGVLLYSYDT--GSKDFLSINLAG 434
Query: 1698 RRLEFRYDLGKGAAVIRSREPVTLGAWTRVSLERNGRKGALRVGDGPRVLGESPVPHTVL 1757
+EFR+D G G V+RS +P+TLG W + + R + G L+V V G + T +
Sbjct: 435 GHVEFRFDCGSGTGVLRSEDPLTLGNWHELRVSRTAKNGILQVDKQKIVEGMAEGGFTQI 494
Query: 1758 NLKEPLYVGGAPDFSKLARAAAVSSGFDGAIQLVSLGGRQLLTPEHVLRQVDVTSFAGHP 1817
+++GG P++ + + + V F G+IQ + L R + V+V + A HP
Sbjct: 495 KCNTDIFIGGVPNYDDVKKNSGVLKPFSGSIQKIILNDRTIHVKHDFTSGVNVEN-AAHP 553
Query: 1818 CTRASGHPCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVEKSAGDVDTLAFDGRTFVEY 1877
C RA PC +G SC PR+ Y C CP GF G HC+K ++E ++ F GR+++ Y
Sbjct: 554 CVRA---PCAHGGSCRPRKEGYDCDCPLGFEGLHCQKAIIEA----IEIPQFIGRSYLTY 606
Query: 1878 LNA-VTESEKALQSNHFELSLRTEATQGLVLWSGKATER--ADYVALAIVDGHLQLSYNL 1934
N + + +SN F + +T A GL+LW G + R +D+++L + DG L SYNL
Sbjct: 607 DNPDILKRVSGSRSNVF-MRFKTTAKDGLLLWRGDSPMRPNSDFISLGLRDGALVFSYNL 665
Query: 1935 GSQPVVLRSTVPVNTNRWLRVVAHREQREGSLQVGNEAPVTGSSPLGATQLDTDGALWLG 1994
GS + N RW RV A R+ + G + V + TG SP QL+ +GAL++G
Sbjct: 666 GSGVASIMVNGSFNDGRWHRVKAVRDGQSGKITVDDYGARTGKSPGMMRQLNINGALYVG 725
Query: 1995 GLPELPVGPALPKAYGTGFVGCLRDVVVGR-HPLHLLEDAVTKPELRPC 2042
G+ E+ + + Y G VGC+ + + + L+EDAV + C
Sbjct: 726 GMKEIAL--HTNRQYMRGLVGCISHFTLSTDYHISLVEDAVDGKNINTC 772
>gi|33469929 EGF-like, fibronectin type III and laminin G domains
isoform 1 [Homo sapiens]
Length = 1009
Score = 328 bits (840), Expect = 4e-89
Identities = 234/769 (30%), Positives = 355/769 (46%), Gaps = 79/769 (10%)
Query: 1290 HPSHTSQPVAKTTAA-PTTRRPPTTAPSRVPGRRPPAPQQP--PKPCDSQPCFHGGTCQD 1346
+P S+ + T+A+ P T P P + G+ A PCD C C +
Sbjct: 301 NPKTISRLIPPTSASLPVTTVAPQPIPIQRKGKNGVAIMSRLFDMPCDETLCSADSFCVN 360
Query: 1347 WALGGGFTCSCPAGRGGAVCEKVLGAPVPAFEGRSFLAFPTLR-AYHTLRLALEFRALEP 1405
GG C C G+GG C + + P F G S++ F L+ +Y ++ LEFRA
Sbjct: 361 DYTWGGSRCQCTLGKGGESCSEDIVIQYPQFFGHSYVTFEPLKNSYQAFQITLEFRAEAE 420
Query: 1406 QGLLLYNG-NARGK-DFLALALLDGRVQLRFDTGSGPAVLTSAVPVEPGQWHRLELSRHW 1463
GLLLY G N G+ DF++LA++ +Q RF+ G+G A++ S ++ G WH + L R
Sbjct: 421 DGLLLYCGENEHGRGDFMSLAIIRRSLQFRFNCGTGVAIIVSETKIKLGGWHTVMLYRDG 480
Query: 1464 RRGTLSVDGETPVLGESPSGTDGLNLDTDLFVGGVPEDQAAVALERTFVGAGLRGCIRLL 1523
G L ++ TPV G+S + T L++GG P A + T G +GC++ L
Sbjct: 481 LNGLLQLNNGTPVTGQSQGQYSKITFRTPLYLGGAPS--AYWLVRATGTNRGFQGCVQSL 538
Query: 1524 DVNNQRLELGIGP-GAATRGSGVGECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVG 1582
VN +R+++ P G A G+ VGEC C C G C ++A +
Sbjct: 539 AVNGRRIDMRPWPLGKALSGADVGECSSGICDEASCIHGGTCTAIKADSYI--------- 589
Query: 1583 PTCADEKSPCQPNPCHGAAPCRVLPEGGAQCECPLGREGTFCQTASGQDGSGPFLADFNG 1642
C CPLG +G C+ A F
Sbjct: 590 ------------------------------CLCPLGFKGRHCEDA--------FTLTIPQ 611
Query: 1643 FSHLELRGLHTFARDLGEK-----MALEVVFLARGPSGLLLYNGQKTDGKGDFVSLALRD 1697
F LR L + M E+ F G+LLY+ G DF+S+ L
Sbjct: 612 FRE-SLRSYAATPWPLEPQHYLSFMEFEITFRPDSGDGVLLYSYDT--GSKDFLSINLAG 668
Query: 1698 RRLEFRYDLGKGAAVIRSREPVTLGAWTRVSLERNGRKGALRVGDGPRVLGESPVPHTVL 1757
+EFR+D G G V+RS +P+TLG W + + R + G L+V V G + T +
Sbjct: 669 GHVEFRFDCGSGTGVLRSEDPLTLGNWHELRVSRTAKNGILQVDKQKIVEGMAEGGFTQI 728
Query: 1758 NLKEPLYVGGAPDFSKLARAAAVSSGFDGAIQLVSLGGRQLLTPEHVLRQVDVTSFAGHP 1817
+++GG P++ + + + V F G+IQ + L R + V+V + A HP
Sbjct: 729 KCNTDIFIGGVPNYDDVKKNSGVLKPFSGSIQKIILNDRTIHVKHDFTSGVNVEN-AAHP 787
Query: 1818 CTRASGHPCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVEKSAGDVDTLAFDGRTFVEY 1877
C RA PC +G SC PR+ Y C CP GF G HC+K ++E ++ F GR+++ Y
Sbjct: 788 CVRA---PCAHGGSCRPRKEGYDCDCPLGFEGLHCQKAIIEA----IEIPQFIGRSYLTY 840
Query: 1878 LNA-VTESEKALQSNHFELSLRTEATQGLVLWSGKATER--ADYVALAIVDGHLQLSYNL 1934
N + + +SN F + +T A GL+LW G + R +D+++L + DG L SYNL
Sbjct: 841 DNPDILKRVSGSRSNVF-MRFKTTAKDGLLLWRGDSPMRPNSDFISLGLRDGALVFSYNL 899
Query: 1935 GSQPVVLRSTVPVNTNRWLRVVAHREQREGSLQVGNEAPVTGSSPLGATQLDTDGALWLG 1994
GS + N RW RV A R+ + G + V + TG SP QL+ +GAL++G
Sbjct: 900 GSGVASIMVNGSFNDGRWHRVKAVRDGQSGKITVDDYGARTGKSPGMMRQLNINGALYVG 959
Query: 1995 GLPELPVGPALPKAYGTGFVGCLRDVVVGR-HPLHLLEDAVTKPELRPC 2042
G+ E+ + + Y G VGC+ + + + L+EDAV + C
Sbjct: 960 GMKEIAL--HTNRQYMRGLVGCISHFTLSTDYHISLVEDAVDGKNINTC 1006
>gi|33469935 EGF-like, fibronectin type III and laminin G domains
isoform 3 [Homo sapiens]
Length = 375
Score = 206 bits (524), Expect = 2e-52
Identities = 128/385 (33%), Positives = 198/385 (51%), Gaps = 17/385 (4%)
Query: 1662 MALEVVFLARGPSGLLLYNGQKTDGKGDFVSLALRDRRLEFRYDLGKGAAVIRSREPVTL 1721
M E+ F G+LLY+ G DF+S+ L +EFR+D G G V+RS +P+TL
Sbjct: 1 MEFEITFRPDSGDGVLLYSYDT--GSKDFLSINLAGGHVEFRFDCGSGTGVLRSEDPLTL 58
Query: 1722 GAWTRVSLERNGRKGALRVGDGPRVLGESPVPHTVLNLKEPLYVGGAPDFSKLARAAAVS 1781
G W + + R + G L+V V G + T + +++GG P++ + + + V
Sbjct: 59 GNWHELRVSRTAKNGILQVDKQKIVEGMAEGGFTQIKCNTDIFIGGVPNYDDVKKNSGVL 118
Query: 1782 SGFDGAIQLVSLGGRQLLTPEHVLRQVDVTSFAGHPCTRASGHPCLNGASCVPREAAYVC 1841
F G+IQ + L R + V+V + A HPC RA PC +G SC PR+ Y C
Sbjct: 119 KPFSGSIQKIILNDRTIHVKHDFTSGVNVEN-AAHPCVRA---PCAHGGSCRPRKEGYDC 174
Query: 1842 LCPGGFSGPHCEKGLVEKSAGDVDTLAFDGRTFVEYLNA-VTESEKALQSNHFELSLRTE 1900
CP GF G HC+K ++E ++ F GR+++ Y N + + +SN F + +T
Sbjct: 175 DCPLGFEGLHCQKAIIEA----IEIPQFIGRSYLTYDNPDILKRVSGSRSNVF-MRFKTT 229
Query: 1901 ATQGLVLWSGKATER--ADYVALAIVDGHLQLSYNLGSQPVVLRSTVPVNTNRWLRVVAH 1958
A GL+LW G + R +D+++L + DG L SYNLGS + N RW RV A
Sbjct: 230 AKDGLLLWRGDSPMRPNSDFISLGLRDGALVFSYNLGSGVASIMVNGSFNDGRWHRVKAV 289
Query: 1959 REQREGSLQVGNEAPVTGSSPLGATQLDTDGALWLGGLPELPVGPALPKAYGTGFVGCLR 2018
R+ + G + V + TG SP QL+ +GAL++GG+ E+ + + Y G VGC+
Sbjct: 290 RDGQSGKITVDDYGARTGKSPGMMRQLNINGALYVGGMKEIAL--HTNRQYMRGLVGCIS 347
Query: 2019 DVVVGR-HPLHLLEDAVTKPELRPC 2042
+ + + L+EDAV + C
Sbjct: 348 HFTLSTDYHISLVEDAVDGKNINTC 372
Score = 146 bits (368), Expect = 2e-34
Identities = 116/380 (30%), Positives = 161/380 (42%), Gaps = 50/380 (13%)
Query: 1394 LRLALEFRALEPQGLLLYNGNARGKDFLALALLDGRVQLRFDTGSGPAVLTSAVPVEPGQ 1453
+ + FR G+LLY+ + KDFL++ L G V+ RFD GSG VL S P+ G
Sbjct: 1 MEFEITFRPDSGDGVLLYSYDTGSKDFLSINLAGGHVEFRFDCGSGTGVLRSEDPLTLGN 60
Query: 1454 WHRLELSRHWRRGTLSVDGETPVLGESPSGTDGLNLDTDLFVGGVPEDQAAVALERTFVG 1513
WH L +SR + G L VD + V G + G + +TD+F+GGVP + + V
Sbjct: 61 WHELRVSRTAKNGILQVDKQKIVEGMAEGGFTQIKCNTDIFIGGVPNYDD--VKKNSGVL 118
Query: 1514 AGLRGCIRLLDVNNQRLELGIGPGAATRGSGVGECGDHPCLPNPCHGGAPCQNLEAGRFH 1573
G I+ + +N++ + + T G V E HPC+ PC G C+ + G +
Sbjct: 119 KPFSGSIQKIILNDRTIHV---KHDFTSGVNV-ENAAHPCVRAPCAHGGSCRPRKEG-YD 173
Query: 1574 CQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQCECPLGREGTFCQTASGQDGS 1633
C CP LG EG CQ A +
Sbjct: 174 CDCP---------------------------------------LGFEGLHCQKAIIEAIE 194
Query: 1634 GPFLADFNGFSHLELRGLHTFARDLGEKMALEVVFLARGPSGLLLYNGQK-TDGKGDFVS 1692
P F G S+L R G + + + F GLLL+ G DF+S
Sbjct: 195 IP---QFIGRSYLTYDNPDILKRVSGSRSNVFMRFKTTAKDGLLLWRGDSPMRPNSDFIS 251
Query: 1693 LALRDRRLEFRYDLGKGAAVIRSREPVTLGAWTRVSLERNGRKGALRVGDGPRVLGESPV 1752
L LRD L F Y+LG G A I G W RV R+G+ G + V D G+SP
Sbjct: 252 LGLRDGALVFSYNLGSGVASIMVNGSFNDGRWHRVKAVRDGQSGKITVDDYGARTGKSPG 311
Query: 1753 PHTVLNLKEPLYVGGAPDFS 1772
LN+ LYVGG + +
Sbjct: 312 MMRQLNINGALYVGGMKEIA 331
Score = 97.4 bits (241), Expect = 1e-19
Identities = 65/199 (32%), Positives = 100/199 (50%), Gaps = 15/199 (7%)
Query: 1332 PCDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEKVL--GAPVPAFEGRSFLAFPT-- 1387
PC PC HGG+C+ G+ C CP G G C+K + +P F GRS+L +
Sbjct: 153 PCVRAPCAHGGSCRPRK--EGYDCDCPLGFEGLHCQKAIIEAIEIPQFIGRSYLTYDNPD 210
Query: 1388 -LRAYHTLR--LALEFRALEPQGLLLYNGNAR---GKDFLALALLDGRVQLRFDTGSGPA 1441
L+ R + + F+ GLLL+ G++ DF++L L DG + ++ GSG A
Sbjct: 211 ILKRVSGSRSNVFMRFKTTAKDGLLLWRGDSPMRPNSDFISLGLRDGALVFSYNLGSGVA 270
Query: 1442 VLTSAVPVEPGQWHRLELSRHWRRGTLSVDGETPVLGESPSGTDGLNLDTDLFVGGVPED 1501
+ G+WHR++ R + G ++VD G+SP LN++ L+VGG+ E
Sbjct: 271 SIMVNGSFNDGRWHRVKAVRDGQSGKITVDDYGARTGKSPGMMRQLNINGALYVGGMKE- 329
Query: 1502 QAAVALERTFVGAGLRGCI 1520
A+ R ++ GL GCI
Sbjct: 330 -IALHTNRQYM-RGLVGCI 346
>gi|224451128 eyes shut homolog isoform 1 [Homo sapiens]
Length = 3144
Score = 202 bits (515), Expect = 2e-51
Identities = 200/781 (25%), Positives = 319/781 (40%), Gaps = 115/781 (14%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEKVLGAPVPAFEGRSFLAFPTLRAYH 1392
C++ PC +G TC + G C CP GR G +C + P F G + + AY
Sbjct: 2375 CENNPCGNGATCVPKS-GTDIVCLCPYGRSGPLCTDAINITQPRFSGTDAFGYTSFLAYS 2433
Query: 1393 TL-------------RLALEFRALEPQGLLLYNGNA----RGKDFLALALLDGRVQLRFD 1435
+ +LA AL+ L+ + G G DFLA+ LL+G V ++
Sbjct: 2434 RISDISFHYEFHLKFQLANNHSALQ-NNLIFFTGQKGHGLNGDDFLAVGLLNGSVVYSYN 2492
Query: 1436 TGSGPAVLTSAVPVEPGQWHRLELSRHWRRGTLSVDGETPVLGESPSGTDGLNLDTDLFV 1495
GSG A + S H + L + ++ G L VD +P GLN+ + +V
Sbjct: 2493 LGSGIASIRSEPLNLSLGVHTVHLGKFFQEGWLKVDDHKNKSIIAPGRLVGLNVFSQFYV 2552
Query: 1496 GGVPEDQAAVALERTFVGAGLRGCIRLLDVNNQR----LELGIGPGAATRGSGVGECGDH 1551
GG E + G +GCI L V ++ LG G G VG+C
Sbjct: 2553 GGYSEYTPDLLPNGADFKNGFQGCIFTLQVRTEKDGHFRGLGNPEGHPNAGRSVGQCHAS 2612
Query: 1552 PCLPNPCHGGAPCQNLEAGR-FHCQCPPGRVGPTCADEKSPCQP-----NPCHGAAPCRV 1605
PC C G C +E+G +C C G G C + S C P + C A C
Sbjct: 2613 PCSLMKCGNGGTC--IESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCIS 2670
Query: 1606 LPEGGAQCECPLGREGTFCQTA-SGQDGSGPFLADFNGFSHLELRGLHTFARDLGEKMAL 1664
LP G C CPLG G +C+ A S D S F EL + + + +K +
Sbjct: 2671 LPHGYT-CFCPLGTTGIYCEQALSISDPS---------FRSNELSWMSFASFHVRKKTHI 2720
Query: 1665 EVVFLARGPSGLLLYNGQKTDGK-GDFVSLALRDRRLEFRYDLGKGAAVIRSREPVTLGA 1723
++ F G+L Y Q + GDF+ ++L + ++ RY+LG ++ + + VT+
Sbjct: 2721 QLQFQPLAADGILFYAAQHLKAQSGDFLCISLVNSSVQLRYNLGDRTIILETLQKVTING 2780
Query: 1724 --WTRVSLERNGRKGALRVGDGPRVLGESPVPHTVLNLKEPLYVGGAPDFSKLARAAAVS 1781
W + R G +G L + DG V ++ + L+ Y+GG + L A+
Sbjct: 2781 STWHIIKAGRVGAEGYLDL-DGINVTEKASTKMSSLDTNTDFYIGGVSSLN-LVNPMAIE 2838
Query: 1782 S---GFDGAIQLVSLGGRQL-LTPEHVLRQVDVTSFAGHPCTRASGHPCLNGAS------ 1831
+ GF G I+ V + ++L LT +V G C + C NG
Sbjct: 2839 NEPVGFQGCIRQVIINNQELQLTEFGAKGGSNVGDCDGTAC---GYNTCRNGGECTVNGT 2895
Query: 1832 -------------------------------CVPREA-AYVCLCPGGFSGPHCEKGLVEK 1859
C+P ++ +Y CLC G+ G +CE
Sbjct: 2896 TFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCE------ 2949
Query: 1860 SAGDVDTLAFDGRTFVEYLNAVTESEKALQSNHFELSLRTEATQGLVLWSGKA-TERADY 1918
+ T F G ++++Y++ + LQ L+ T T+GL++W G A E D+
Sbjct: 2950 NKTSFSTAKFMGNSYIKYIDP-NYRMRNLQFTTISLNFSTTKTEGLIVWMGIAQNEENDF 3008
Query: 1919 VALAIVDGHLQLSYNLGSQPVVLRSTVPVN-------TNRWLRVVAHREQREGSLQVGNE 1971
+A+ + + L+++ NLG R +VP++ N+W VV + Q + N
Sbjct: 3009 LAIGLHNQTLKIAVNLGE-----RISVPMSYNNGTFCCNKWHHVVVIQNQTLIKAYINNS 3063
Query: 1972 APVTG--SSPLGATQLDTDGALWLGGLP-ELPVGPALPKAYGTGFVGCLRDVVVGRHPLH 2028
++ L+ DG +LGG V + + T FVG ++DVV + P +
Sbjct: 3064 LILSEDIDPHKNFVALNYDGICYLGGFEYGRKVNIVTQEIFKTNFVGKIKDVVFFQEPKN 3123
Query: 2029 L 2029
+
Sbjct: 3124 I 3124
Score = 196 bits (497), Expect = 3e-49
Identities = 207/796 (26%), Positives = 326/796 (40%), Gaps = 127/796 (15%)
Query: 1330 PKPCDSQPCFHGGTCQDWALGGG---FTCSCPAGRGGAVCEKVLGAPVPAFEGRSFLAFP 1386
P C C +GGTC L G F C CP G CEK G P+F G S+L P
Sbjct: 2100 PSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDAGLFFPSFNGNSYLELP 2159
Query: 1387 TLRAY------HTLRLALEFRALEPQGLLLY-NGNARGKDFLALALLDGRVQLRFDTGSG 1439
L+ T+ + L + G +LY NGN GK FL L L++GR +++ G+
Sbjct: 2160 FLKFVLEKEHNRTVTIYLTIKTNSLNGTILYSNGNNCGKQFLHLFLVEGRPSVKYGCGNS 2219
Query: 1440 PAVLTSAV--PVEPGQWHRLELSRHWRRGT--------LSVDGETPVLGESPSGTDGLNL 1489
+LT + + + + + G+ ++ DG+ PV + +
Sbjct: 2220 QNILTVSANYSINTNAFTPITIRYTTPVGSPGVVCMIEMTADGKPPVQKKDTEISHASQA 2279
Query: 1490 DTD-LFVGGVPEDQAAVALERTFVGA-GLRGCIRLLDVNNQRLELGIGPGAATRGSGVGE 1547
+ +F+G +P A V + + G RGCI L VNN+ + A G +
Sbjct: 2280 YFESMFLGHIP---ANVQIHKKAGPVYGFRGCILDLQVNNKEFFI---IDEARHGKNIEN 2333
Query: 1548 CGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLP 1607
C C + C C + F C+CP G C + + C+ NPC A C +P
Sbjct: 2334 CHVPWCAHHLCRNNGTCISDNENLF-CECPRLYSGKLC--QFASCENNPCGNGATC--VP 2388
Query: 1608 EGGAQ--CECPLGREGTFCQTA--------SGQDGSGPFLADFNGFSHLELRGLHTFARD 1657
+ G C CP GR G C A SG D G F +S + H +
Sbjct: 2389 KSGTDIVCLCPYGRSGPLCTDAINITQPRFSGTDAFG--YTSFLAYSRISDISFH-YEFH 2445
Query: 1658 LGEKMALEVVFLARGPSGLLLYNGQKTDGKG--DFVSLALRDRRLEFRYDLGKGAAVIRS 1715
L ++A L + L+ + GQK G DF+++ L + + + Y+LG G A IRS
Sbjct: 2446 LKFQLANNHSAL---QNNLIFFTGQKGHGLNGDDFLAVGLLNGSVVYSYNLGSGIASIRS 2502
Query: 1716 REP--VTLGAWTRVSLERNGRKGALRVGDGPRVLGESPVPHTVLNLKEPLYVGGAPDFSK 1773
EP ++LG T V L + ++G L+V D +P LN+ YVGG +++
Sbjct: 2503 -EPLNLSLGVHT-VHLGKFFQEGWLKVDDHKNKSIIAPGRLVGLNVFSQFYVGGYSEYTP 2560
Query: 1774 --LARAAAVSSGFDGAIQLVSLGG------RQLLTPE---HVLRQVD------------- 1809
L A +GF G I + + R L PE + R V
Sbjct: 2561 DLLPNGADFKNGFQGCIFTLQVRTEKDGHFRGLGNPEGHPNAGRSVGQCHASPCSLMKCG 2620
Query: 1810 ----------------VTSFAGHPCTRASG---------HPCLNGASCVPREAAYVCLCP 1844
T + G CT H C GA+C+ Y C CP
Sbjct: 2621 NGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCFCP 2680
Query: 1845 GGFSGPHCEKGLVEKS----AGDVDTLAFDGRTFVEYLNAVTESEKALQSNHFELSLRTE 1900
G +G +CE+ L + ++ ++F S + H +L +
Sbjct: 2681 LGTTGIYCEQALSISDPSFRSNELSWMSF-------------ASFHVRKKTHIQLQFQPL 2727
Query: 1901 ATQGLVLWSGK--ATERADYVALAIVDGHLQLSYNLGSQPVVLRS--TVPVNTNRWLRVV 1956
A G++ ++ + + D++ +++V+ +QL YNLG + ++L + V +N + W +
Sbjct: 2728 AADGILFYAAQHLKAQSGDFLCISLVNSSVQLRYNLGDRTIILETLQKVTINGSTWHIIK 2787
Query: 1957 AHREQREGSLQVGNEAPVTGSSPLGATQLDTDGALWLGGLPELP-VGPALPKAYGTGFVG 2015
A R EG L + + VT + + LDT+ ++GG+ L V P + GF G
Sbjct: 2788 AGRVGAEGYLDL-DGINVTEKASTKMSSLDTNTDFYIGGVSSLNLVNPMAIENEPVGFQG 2846
Query: 2016 CLRDVVVGRHPLHLLE 2031
C+R V++ L L E
Sbjct: 2847 CIRQVIINNQELQLTE 2862
Score = 110 bits (276), Expect = 1e-23
Identities = 154/720 (21%), Positives = 273/720 (37%), Gaps = 109/720 (15%)
Query: 1377 FEGRSFLAFPTLRAYHTLRLALEFRALEPQGLLLY---NGNARGKDFLALALLDGRVQLR 1433
+ G S+L F + ++LEF+ GLLLY + N F+ L + +G ++
Sbjct: 1888 YYGDSYLEFQNVALNPQNNISLEFQTFSSYGLLLYVKQDSNLVDGFFIQLFIENGTLKYH 1947
Query: 1434 FDTGSGPAV--LTSAVPVEPGQWHRLELSRHWRRGTLSVDGETPVLGESPSGTDGLN--- 1488
F + + V V+ GQ + L + R+ + E +LG + + +N
Sbjct: 1948 FYCPGEAKFKSINTTVRVDNGQKYTLLI----RQELDPCNAELTILGRNTQICESINHVL 2003
Query: 1489 -----LDTDLFVGGVPEDQAAVALERTFVGAGLRGCIRLLDVNNQRLELGIGPGAATRGS 1543
+F+GG P+ + + GCI ++++NN R + P A +
Sbjct: 2004 GKPLPKSGSVFIGGFPDLHGKIQMPVPV--KNFTGCIEVIEINNWRSFI---PSKAVKNY 2058
Query: 1544 GVGECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPC 1603
+ C + +P ++ G V P+ A S CQ + CH C
Sbjct: 2059 HINNCRSQGFMLSPTASFVDASDVTQG---VDTMWTSVSPSVA-APSVCQQDVCHNGGTC 2114
Query: 1604 RV--LPEG--GAQCECPLGREGTFCQTASGQDGSGPFLADFNGFSHLELRGLH-TFARDL 1658
L G QC+CPL G FC+ +G F FNG S+LEL L ++
Sbjct: 2115 HAIFLSSGIVSFQCDCPLHFTGRFCEKDAGL-----FFPSFNGNSYLELPFLKFVLEKEH 2169
Query: 1659 GEKMALEVVFLARGPSGLLLYNGQKTDGKGDFVSLALRDRRLEFRYDLGKGAAV--IRSR 1716
+ + + +G +LY+ GK F+ L L + R +Y G + + +
Sbjct: 2170 NRTVTIYLTIKTNSLNGTILYSNGNNCGK-QFLHLFLVEGRPSVKYGCGNSQNILTVSAN 2228
Query: 1717 EPVTLGAWTRVSLERNGRKGALRV---------GDGPRVLGESPVPHTVLNLKEPLYVGG 1767
+ A+T +++ G+ V G P ++ + H E +++G
Sbjct: 2229 YSINTNAFTPITIRYTTPVGSPGVVCMIEMTADGKPPVQKKDTEISHASQAYFESMFLGH 2288
Query: 1768 APDFSKLARAAAVSSGFDGAIQLVSLGGRQLLTPEHVLRQVDVTSFAGHPCTRASGHPCL 1827
P ++ + A GF G I + + ++ + ++ + C H C
Sbjct: 2289 IPANVQIHKKAGPVYGFRGCILDLQVNNKEFFIIDEARHGKNIENCHVPWCAH---HLCR 2345
Query: 1828 NG------------------------------------ASCVPREAA-YVCLCPGGFSGP 1850
N A+CVP+ VCLCP G SGP
Sbjct: 2346 NNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSGTDIVCLCPYGRSGP 2405
Query: 1851 HCEKGLVEKSAGDVDTLAFDGRTFVEYLNAVTESEKALQSNHFELSLRTEAT-------Q 1903
C + ++ F G Y + + S + S H+E L+ +
Sbjct: 2406 LCTDAI------NITQPRFSGTDAFGYTSFLAYSRISDISFHYEFHLKFQLANNHSALQN 2459
Query: 1904 GLVLWSGK---ATERADYVALAIVDGHLQLSYNLGSQPVVLRSTVPVNTNRWLRVV-AHR 1959
L+ ++G+ D++A+ +++G + SYNLGS +RS P+N + + V +
Sbjct: 2460 NLIFFTGQKGHGLNGDDFLAVGLLNGSVVYSYNLGSGIASIRSE-PLNLSLGVHTVHLGK 2518
Query: 1960 EQREGSLQVGNEAPVTGSSPLGATQLDTDGALWLGGLPELPVGPALPKA--YGTGFVGCL 2017
+EG L+V + + +P L+ ++GG E LP + GF GC+
Sbjct: 2519 FFQEGWLKVDDHKNKSIIAPGRLVGLNVFSQFYVGGYSEY-TPDLLPNGADFKNGFQGCI 2577
Score = 60.8 bits (146), Expect = 1e-08
Identities = 121/556 (21%), Positives = 176/556 (31%), Gaps = 133/556 (23%)
Query: 172 CRGMLCGFGAVCEPNAEGP--GRASCVCKKSPCPSVVAPVCGSDASTYSNECEL--QRAQ 227
C+ + + VC + EG + S CK +PC + C +Y EC
Sbjct: 748 CKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKN--NSTCTDLYKSYRCECTSGWTGQN 805
Query: 228 CSQQRRIRLLSRGPCGSRDPCSNVTCSFGSTCARSADGLTASCLCPATCRGAPEGTVCGS 287
CS++ C S DPC N G C S CLCP G
Sbjct: 806 CSEEIN-------ECDS-DPCMN-----GGLCHESTIPGQFVCLCPPLYTG--------- 843
Query: 288 DGADYPGECQLLRRACARQENVFKKFDGPC---DPCQGALPDPSRSCRVNPRTRRPEMLL 344
+ C ++ N+ PC C AL D ++ C +
Sbjct: 844 -------------QFCHQRYNLCDLLHNPCRNNSTCL-ALVDANQHCICREEFEGKNCEI 889
Query: 345 RPESCPARQAPVCGDDGVTYENDCVMGRSGAARGLLLQKVRSGQCQGRDQCPEPCRFNAV 404
+ C GD N + R G + L ++ +C EPC+ N
Sbjct: 890 DVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLC--EIEINECSS-----EPCKNNGT 942
Query: 405 CLSRRGRPRCSC----------------------DRVTC----DGAYRPVCAQDGRTYDS 438
C+ R C+C D C DG Y +CA G T
Sbjct: 943 CVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDG-YNCLCA-PGYT-GI 999
Query: 439 DCWRQQAECRQQRAIPSKHQGPC--------DQAPSPCLGVQCAFGATCAVKNGQAACEC 490
+C EC + P H G C S G C A + N C
Sbjct: 1000 NCEINLDECLSE---PCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLHGRC 1056
Query: 491 LQACSSLYDPVCGSDGVTYGSACELEATACTLGREIQVARKGPCDR--------CGQCRF 542
+ + Y C +DG + + C+++ CT I +G C + C +
Sbjct: 1057 TELINE-YPCSCDADGTS--TQCKIKINDCT---SIPCMNEGFCQKSAHGFTCICPRGYT 1110
Query: 543 GALCEAETGRCVCP--SECVALAQPVC-GSDGHTYPSECMLHVHACTHQISLHVASAGPC 599
GA CE C P + + L +C GHT+ C+ +I+++ S+ PC
Sbjct: 1111 GAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPC 1170
Query: 600 ---ETCGDAVCAFGAVCSAG---------------QCVCPRCEHPPPGPVC----GSDGV 637
C D + + C G CV C PG C G
Sbjct: 1171 LHGADCEDHINGYVCKCQPGWSGHHCENELECIPNSCVHELCMENEPGSTCLCTPGFMTC 1230
Query: 638 TYGSAC--ELREAACL 651
+ G C E+R CL
Sbjct: 1231 SIGLLCGDEIRRITCL 1246
Score = 57.8 bits (138), Expect = 1e-07
Identities = 175/881 (19%), Positives = 267/881 (30%), Gaps = 156/881 (17%)
Query: 183 CEPNAEGPGRASCVCKKSPCPSVV---APVCGSDASTYSNECELQRAQCSQQRRIRLLSR 239
C+ GP C PC S++ +C + +S Y+ EC + + + + S
Sbjct: 282 CDEQFSGP---FCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSL 338
Query: 240 GPCGSRDPCSNVTCSFGSTCARSADGLTASCLCPATCRGAP--EGTVCGSDGADYP---- 293
PC + C ++ C+ L + +C P C DYP
Sbjct: 339 VPCQNGTDCIKISNDVMCICSPIFTDLLCKSI-QTSCESFPLRNNATCKKCEKDYPCSCI 397
Query: 294 ------------GECQLLRRACARQE---NVFKKFDGPCDPCQGALPDPSRSCRVNPRTR 338
C+LL C +E N+ +F C P C NP
Sbjct: 398 SGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIP----------GCTKNPCWF 447
Query: 339 RPEMLLRPES---CPARQAPVCGDDG-VTYENDCVMGRSGAARGLLLQKVRSGQCQGRDQ 394
+ L + C +C D G +E +G +G + G Q V
Sbjct: 448 LKNVYLIHQHLCYCGVTFHGICQDKGPAQFEYVWQLGFAG-SEGEKCQGVIDAYFFLAAN 506
Query: 395 CPEPCRF-------NAVC-LSRRGRPR-----CSCDRVTCDGAYRPVC--AQDGRTY-DS 438
C E + N+ C G CSC YR +C G Y ++
Sbjct: 507 CTEDATYVNDPEDNNSSCWFPHEGTKEICANGCSCLSEEDSQEYRYLCFLRWAGNMYLEN 566
Query: 439 DCWRQQAECRQQRAIPSKHQGPCDQAPSPCLGVQCAFGATCAVKNGQAACECLQACSSLY 498
Q+ EC+ + + P +G C + N + L C +L
Sbjct: 567 TTDDQENECQHEAVCKDEINRPRCSCSLSYIGRLCVVNVDYCLGNHSISVHGL--CLAL- 623
Query: 499 DPVCGSDGVT--YGSACELE-----ATACTLGREIQVARKGPCDRCGQCRFGALCEAETG 551
C G+ + CE++ + +C G R +C G CE +
Sbjct: 624 SHNCNCSGLQRYERNICEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDID 683
Query: 552 RCV---CPSECVALAQPVCGSDGHTYPSECMLHVHACTHQISLHVASAGPCETCGDAVCA 608
C C + + QP Y +C+ V C C
Sbjct: 684 ECASHPCKNGATCIDQP------GNYFCQCV---------PPFKVVDGFSC-LCNPGYVG 727
Query: 609 FGAVCSAGQCVCPRCEHPPPGPVCGSDGVTYGSACELREAACLQQTQIEEARAGPCE--- 665
C+ CEH C ++Y C + + E + PC+
Sbjct: 728 IRCEQDIDDCILNACEH---NSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNS 784
Query: 666 ---------QAECGSGGSG---SGEDGDCEQELCRQRGGIWDEDSEDGPCVCDFSCQSVP 713
+ EC SG +G S E +C+ + C GG+ E + G VC C +
Sbjct: 785 TCTDLYKSYRCECTSGWTGQNCSEEINECDSDPC-MNGGLCHESTIPGQFVC--LCPPLY 841
Query: 714 GSPVCGSDGVTYSTECELKKARCESQRGLYVAAQG----ACRGPTFAPLPPVAPLHC--- 766
C Y+ C+L C + CR + C
Sbjct: 842 TGQFCHQ---RYNL-CDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFL 897
Query: 767 AQTPYGCCQDNITAARGVGLAGCPSACQCNPHGSYGGTCDPATGQCSCRPGVGGLRC--- 823
+ YG C+D + R C C P G G C+ +CS P C
Sbjct: 898 SCQDYGDCEDMVNNFR----------CICRP-GFSGSLCEIEINECSSEPCKNNGTCVDL 946
Query: 824 -----DRCEPGFWNFRGIVTDGRSGCTPCSCDPQGAVRDDCEQMTGLCSCKPGVAGPKC- 877
CEP + + + +PC + R D C C PG G C
Sbjct: 947 TNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYN----CLCAPGYTGINCE 1002
Query: 878 ---GQCPDGRALGPAGCEADASAPATCAEMRCEFGARCVEESGSAHCV---CPMLTCPEA 931
+C L C D TC FG C E+ + C+ C C E
Sbjct: 1003 INLDECLSEPCLHDGVC-IDGINHYTCDCKSGFFGTHC--ETNANDCLSNPCLHGRCTEL 1059
Query: 932 NATKVCGSDGVTYGNECQLKTIACRQGLQISIQSLGPCQEA 972
C D +C++K C I + G CQ++
Sbjct: 1060 INEYPCSCDADGTSTQCKIKINDC---TSIPCMNEGFCQKS 1097
Score = 57.8 bits (138), Expect = 1e-07
Identities = 136/630 (21%), Positives = 196/630 (31%), Gaps = 123/630 (19%)
Query: 377 RGLLLQKVRSG----QCQ-GRDQCPE-PCRFNAVCLSRRGRPRCSC-------DRVTC-- 421
RG +K G QC+ D+C PC+ A C+ + G C C D +C
Sbjct: 662 RGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLC 721
Query: 422 -DGAYRPVCAQDGRTYDSDCWRQQAECRQ-----QRAIPSKHQGP-CDQAPSPCLGVQCA 474
G C QD + + C+ Q S +G C+Q + C C
Sbjct: 722 NPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCK 781
Query: 475 FGATCAVKNGQAACECL-----QACSSLYDPVCGSDGVTYGSACELEATACTLGREIQVA 529
+TC CEC Q CS + C SD G C E+T G+ + +
Sbjct: 782 NNSTCTDLYKSYRCECTSGWTGQNCSEEINE-CDSDPCMNGGLCH-EST--IPGQFVCLC 837
Query: 530 RKGPCDRCGQCRFGALCEAETGRCVCPSECVAL--AQPVCGSDGHTYPSECMLHVHACTH 587
+ R+ LC+ C S C+AL A C C + V C
Sbjct: 838 PPLYTGQFCHQRYN-LCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDC-- 894
Query: 588 QISLHVASAGPCETCGDAVCAFGAVCSAG------QCVCPRCEHPPPGPVCGSDGV---- 637
+ L G CE D V F +C G + C P C ++G
Sbjct: 895 -LFLSCQDYGDCE---DMVNNFRCICRPGFSGSLCEIEINECSSEP----CKNNGTCVDL 946
Query: 638 --TYGSACELREAACLQQTQIEEARAGPCEQAE------------CGSGGSGSGEDGDCE 683
+ CE + + + + PC E C G +G +CE
Sbjct: 947 TNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGI----NCE 1002
Query: 684 QELCRQRGGIWDEDSEDGPCVCDFSCQSVPGSPVCGSDGVTYSTECELKKARCESQRGLY 743
L ++ PC+ D C C + T CE C S L+
Sbjct: 1003 INL---------DECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLH 1053
Query: 744 VAAQG-------ACRGPTFAPLPPVAPLHCAQTPYGCCQDNITAARGVGLAGCPSACQCN 796
+C + + C P C + G C C
Sbjct: 1054 GRCTELINEYPCSCDADGTSTQCKIKINDCTSIP--CMNEGFCQKSAHGF-----TCIC- 1105
Query: 797 PHGSYGGTCDPATGQCS--------------CRPGVGGLRCDRCEPGFWNFRGIVTDGRS 842
P G G C+ + C+ C G G RC PGF +
Sbjct: 1106 PRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININEC 1165
Query: 843 GCTPCSCDPQGAVRDDCEQMTG--LCSCKPGVAGPKCG---QCPDGRALGPAGCEADASA 897
+PC GA DCE +C C+PG +G C +C + E + +
Sbjct: 1166 SSSPCL---HGA---DCEDHINGYVCKCQPGWSGHHCENELECIPNSCVHELCMENEPGS 1219
Query: 898 PATCAE--MRCEFGARCVEESGSAHCVCPM 925
C M C G C +E C+ P+
Sbjct: 1220 TCLCTPGFMTCSIGLLCGDEIRRITCLTPI 1249
Score = 47.8 bits (112), Expect = 1e-04
Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 4/74 (5%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCR--VLPEGG 1610
C NPC + C +L + C+C G G C++E + C +PC C +P G
Sbjct: 775 CKMNPCKNNSTCTDLYKS-YRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIP-GQ 832
Query: 1611 AQCECPLGREGTFC 1624
C CP G FC
Sbjct: 833 FVCLCPPLYTGQFC 846
Score = 47.4 bits (111), Expect = 1e-04
Identities = 30/96 (31%), Positives = 39/96 (40%), Gaps = 5/96 (5%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQ 1612
C PC C +L RF C C P GP C + + C+ +PC C V G
Sbjct: 932 CSSEPCKNNGTCVDL-TNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENC-VYRTDGYN 989
Query: 1613 CECPLGREGTFCQTASGQDGSGPFLAD---FNGFSH 1645
C C G G C+ + S P L D +G +H
Sbjct: 990 CLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINH 1025
Score = 46.6 bits (109), Expect = 2e-04
Identities = 25/83 (30%), Positives = 35/83 (42%), Gaps = 6/83 (7%)
Query: 1545 VGECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQ--PNPCHGAAP 1602
+ EC PC+ +GG ++ G+F C CPP G C + C NPC +
Sbjct: 810 INECDSDPCM----NGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNST 865
Query: 1603 CRVLPEGGAQCECPLGREGTFCQ 1625
C L + C C EG C+
Sbjct: 866 CLALVDANQHCICREEFEGKNCE 888
Score = 45.8 bits (107), Expect = 4e-04
Identities = 29/97 (29%), Positives = 38/97 (39%), Gaps = 16/97 (16%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCP--------------PGRVGPTCADEKSPCQPNPCH 1598
C +PC GA C + + G + CQC PG VG C + C N C
Sbjct: 685 CASHPCKNGATCID-QPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACE 743
Query: 1599 GAAPCRVLPEGGAQCECPLGREGTFCQTASGQDGSGP 1635
+ C+ L QC C EG FC+ S + P
Sbjct: 744 HNSTCKDL-HLSYQCVCLSDWEGNFCEQESNECKMNP 779
Score = 44.7 bits (104), Expect = 0.001
Identities = 24/83 (28%), Positives = 35/83 (42%), Gaps = 2/83 (2%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQ 1612
C+ N C + C++L + C C G C E + C+ NPC + C L + +
Sbjct: 737 CILNACEHNSTCKDLHLS-YQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYK-SYR 794
Query: 1613 CECPLGREGTFCQTASGQDGSGP 1635
CEC G G C + S P
Sbjct: 795 CECTSGWTGQNCSEEINECDSDP 817
Score = 44.7 bits (104), Expect = 0.001
Identities = 25/67 (37%), Positives = 30/67 (44%), Gaps = 4/67 (5%)
Query: 1794 GGRQLLTPEHVLRQVDVTSFAGHPC----TRASGHPCLNGASCVPREAAYVCLCPGGFSG 1849
GG + P H + F+G C S PCL+GA C YVC C G+SG
Sbjct: 1134 GGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQPGWSG 1193
Query: 1850 PHCEKGL 1856
HCE L
Sbjct: 1194 HHCENEL 1200
Score = 42.7 bits (99), Expect = 0.004
Identities = 23/81 (28%), Positives = 33/81 (40%), Gaps = 7/81 (8%)
Query: 1553 CLPNPCHGGAPC----QNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPC-HGAAPCRVLP 1607
C PC C +N + + C C P G C++ CQP+ C HG C +
Sbjct: 217 CSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHG--NCSNIT 274
Query: 1608 EGGAQCECPLGREGTFCQTAS 1628
CEC G FC+ ++
Sbjct: 275 SNSFICECDEQFSGPFCEVSA 295
Score = 41.6 bits (96), Expect = 0.008
Identities = 20/36 (55%), Positives = 21/36 (58%), Gaps = 2/36 (5%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEK 1368
C S PC + G CQ A GFTC CP G GA CEK
Sbjct: 1083 CTSIPCMNEGFCQKSA--HGFTCICPRGYTGAYCEK 1116
Score = 40.4 bits (93), Expect = 0.018
Identities = 15/36 (41%), Positives = 19/36 (52%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEK 1368
CDS PC +GG C + + G F C CP G C +
Sbjct: 813 CDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQ 848
Score = 39.3 bits (90), Expect = 0.040
Identities = 23/79 (29%), Positives = 30/79 (37%), Gaps = 3/79 (3%)
Query: 1547 ECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVL 1606
E + CL NPC G C L + C C C + + C PC C+
Sbjct: 1040 ETNANDCLSNPCLHGR-CTEL-INEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKS 1097
Query: 1607 PEGGAQCECPLGREGTFCQ 1625
G C CP G G +C+
Sbjct: 1098 AHGFT-CICPRGYTGAYCE 1115
Score = 38.9 bits (89), Expect = 0.052
Identities = 25/89 (28%), Positives = 32/89 (35%), Gaps = 2/89 (2%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQ 1612
CL C C+++ F C C PG G C E + C PC C L
Sbjct: 894 CLFLSCQDYGDCEDM-VNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDL-TNRFF 951
Query: 1613 CECPLGREGTFCQTASGQDGSGPFLADFN 1641
C C G FC+ + P L + N
Sbjct: 952 CNCEPEYHGPFCELDVNKCKISPCLDEEN 980
Score = 38.9 bits (89), Expect = 0.052
Identities = 21/68 (30%), Positives = 27/68 (39%), Gaps = 1/68 (1%)
Query: 1558 CHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQCECPL 1617
C G C + F C+C PG G C + C +PC A C G C+C
Sbjct: 1131 CLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCED-HINGYVCKCQP 1189
Query: 1618 GREGTFCQ 1625
G G C+
Sbjct: 1190 GWSGHHCE 1197
Score = 38.5 bits (88), Expect = 0.068
Identities = 25/85 (29%), Positives = 32/85 (37%), Gaps = 2/85 (2%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQ 1612
C +PC C G ++C C PG G C C PC C +
Sbjct: 970 CKISPCLDEENCVYRTDG-YNCLCAPGYTGINCEINLDECLSEPCLHDGVC-IDGINHYT 1027
Query: 1613 CECPLGREGTFCQTASGQDGSGPFL 1637
C+C G GT C+T + S P L
Sbjct: 1028 CDCKSGFFGTHCETNANDCLSNPCL 1052
Score = 38.5 bits (88), Expect = 0.068
Identities = 12/32 (37%), Positives = 19/32 (59%)
Query: 1825 PCLNGASCVPREAAYVCLCPGGFSGPHCEKGL 1856
PC+N C + C+CP G++G +CEK +
Sbjct: 1087 PCMNEGFCQKSAHGFTCICPRGYTGAYCEKSI 1118
Score = 38.5 bits (88), Expect = 0.068
Identities = 16/38 (42%), Positives = 18/38 (47%), Gaps = 2/38 (5%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEKVL 1370
C S PC HG C+D G+ C C G G CE L
Sbjct: 1165 CSSSPCLHGADCEDHI--NGYVCKCQPGWSGHHCENEL 1200
Score = 37.4 bits (85), Expect = 0.15
Identities = 16/34 (47%), Positives = 21/34 (61%)
Query: 1825 PCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVE 1858
PCL+ +CV R Y CLC G++G +CE L E
Sbjct: 974 PCLDEENCVYRTDGYNCLCAPGYTGINCEINLDE 1007
Score = 36.6 bits (83), Expect = 0.26
Identities = 24/72 (33%), Positives = 33/72 (45%), Gaps = 4/72 (5%)
Query: 1547 ECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVL 1606
E + C +PC GA C++ G + C+C PG G C +E C PN C +
Sbjct: 1159 EININECSSSPCLHGADCEDHING-YVCKCQPGWSGHHCENELE-CIPNSC--VHELCME 1214
Query: 1607 PEGGAQCECPLG 1618
E G+ C C G
Sbjct: 1215 NEPGSTCLCTPG 1226
Score = 36.2 bits (82), Expect = 0.34
Identities = 41/185 (22%), Positives = 57/185 (30%), Gaps = 34/185 (18%)
Query: 795 CNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDPQGA 854
C+ HG T C C+P G C + C+ C G+
Sbjct: 183 CSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELD---------------ACSFKPCKNNGS 227
Query: 855 V---RDDCEQMTGLCSCKPGVAGPKC----GQCPDGRALGPAGCEADASAPATCAEMRCE 907
R++ ++ C C P G C GQC P C + T CE
Sbjct: 228 CINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQ------PHVCFHGNCSNITSNSFICE 281
Query: 908 FGARCVEESGSAHCVCPMLTCPEANATK--VCGSDGVTYGNECQLKTIACRQGLQISIQS 965
C E+ C C K +C + Y EC + + +S S
Sbjct: 282 ----CDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFS 337
Query: 966 LGPCQ 970
L PCQ
Sbjct: 338 LVPCQ 342
Score = 35.8 bits (81), Expect = 0.44
Identities = 26/90 (28%), Positives = 28/90 (31%), Gaps = 6/90 (6%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNP-----CHGAAPCRVLP 1607
C PC CQ G F C CP G G C C C C P
Sbjct: 1083 CTSIPCMNEGFCQKSAHG-FTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGP 1141
Query: 1608 EGGAQCECPLGREGTFCQTASGQDGSGPFL 1637
C C G G FC+ + S P L
Sbjct: 1142 GHTFDCRCLPGFSGQFCEININECSSSPCL 1171
Score = 35.4 bits (80), Expect = 0.58
Identities = 21/69 (30%), Positives = 26/69 (37%), Gaps = 2/69 (2%)
Query: 1547 ECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVL 1606
E C C G +L G F +C PG G C + C +PC A C
Sbjct: 641 EIDTEDCKSASCKNGTTSTHLR-GYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQ 699
Query: 1607 PEGGAQCEC 1615
P G C+C
Sbjct: 700 P-GNYFCQC 707
Score = 35.4 bits (80), Expect = 0.58
Identities = 21/82 (25%), Positives = 28/82 (34%), Gaps = 1/82 (1%)
Query: 1554 LPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQC 1613
L NPC + C L HC C G C + C C C + +C
Sbjct: 856 LHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDM-VNNFRC 914
Query: 1614 ECPLGREGTFCQTASGQDGSGP 1635
C G G+ C+ + S P
Sbjct: 915 ICRPGFSGSLCEIEINECSSEP 936
Score = 35.0 bits (79), Expect = 0.75
Identities = 16/48 (33%), Positives = 21/48 (43%), Gaps = 6/48 (12%)
Query: 1545 VGECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPC 1592
+G+C H C HG C N+ + F C+C GP C PC
Sbjct: 257 IGQCQPHVCF----HGN--CSNITSNSFICECDEQFSGPFCEVSAKPC 298
Score = 34.7 bits (78), Expect = 0.98
Identities = 47/197 (23%), Positives = 73/197 (37%), Gaps = 50/197 (25%)
Query: 774 CQDNITAARGVGLAGCPS-------ACQCNP--HGSY--------------GGTC----- 805
CQ+++++ G C S +C C P G Y G+C
Sbjct: 174 CQESLSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFKPCKNNGSCINKRE 233
Query: 806 --DPATGQCSCRPGVGGLRCD----RCEPGFWNFRGIVTDGRSGCTPCSCDPQGAVRDDC 859
D +C C P G C +C+P F G ++ S C CD Q + C
Sbjct: 234 NWDEQAYECVCHPPFTGKNCSEIIGQCQPHVC-FHGNCSNITSNSFICECDEQFS-GPFC 291
Query: 860 EQMTGLCSCKPGVAGP--KCGQCPDGRALGPAGCEADASAP------ATCAEMRCEFGAR 911
E S KP V+ K G CP+ + C +S+ + + + C+ G
Sbjct: 292 E-----VSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTD 346
Query: 912 CVEESGSAHCVC-PMLT 927
C++ S C+C P+ T
Sbjct: 347 CIKISNDVMCICSPIFT 363
Score = 34.7 bits (78), Expect = 0.98
Identities = 19/65 (29%), Positives = 26/65 (40%), Gaps = 18/65 (27%)
Query: 1810 VTSFAGHPCT----RASGHPCLNGASCVPREAAYV--------------CLCPGGFSGPH 1851
V F G C + HPC NGA+C+ + Y CLC G+ G
Sbjct: 670 VPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIR 729
Query: 1852 CEKGL 1856
CE+ +
Sbjct: 730 CEQDI 734
Score = 34.3 bits (77), Expect = 1.3
Identities = 15/35 (42%), Positives = 18/35 (51%), Gaps = 2/35 (5%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCE 1367
C S+PC H G C D +TC C +G G CE
Sbjct: 1008 CLSEPCLHDGVCIDGI--NHYTCDCKSGFFGTHCE 1040
Score = 34.3 bits (77), Expect = 1.3
Identities = 13/29 (44%), Positives = 15/29 (51%)
Query: 1825 PCLNGASCVPREAAYVCLCPGGFSGPHCE 1853
PCL+ C+ Y C C GF G HCE
Sbjct: 1012 PCLHDGVCIDGINHYTCDCKSGFFGTHCE 1040
Score = 33.9 bits (76), Expect = 1.7
Identities = 84/443 (18%), Positives = 124/443 (27%), Gaps = 111/443 (25%)
Query: 172 CRGMLCGFGAVCEPNAEGPGRASCV-----CKKSPCPSVVAPV-------CGSDASTYSN 219
C M+ F +C P G + C C PC + V C + +
Sbjct: 905 CEDMVNNFRCICRPGFSG---SLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGP 961
Query: 220 ECELQRAQCSQQRRIRLLSRGPCGSRDPCSNVTCSFGSTCARSADG----------LTAS 269
CEL +C PC + C T + CA G L+
Sbjct: 962 FCELDVNKCKIS---------PCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEP 1012
Query: 270 CLCPATCRGAPEGTVCGSDGADYPGECQLLRRACARQENVFKKFDGPC--DPCQGALPDP 327
CL C C + C+ C PC C + +
Sbjct: 1013 CLHDGVCIDGINHYTCDCKSGFFGTHCETNANDC---------LSNPCLHGRCTELINEY 1063
Query: 328 SRSCRVNPRTRRPEMLLRP-ESCPARQAPVCGDDGVTYENDCVMGRSGAARGLLLQKVRS 386
SC + + + ++ + S P C + C G +GA
Sbjct: 1064 PCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGA----------- 1112
Query: 387 GQCQGR-DQCPEPCRFNAVCLSRRGRPRCSCDRVTCDGAYRPVCAQDGRTYDSDCWRQQA 445
C+ D C EP + +CL+ +C DG + DC
Sbjct: 1113 -YCEKSIDNCAEPELNSVICLNGG------------------ICV-DGPGHTFDC----- 1147
Query: 446 ECRQQRAIPSKHQGPCDQAPSPCLGVQCAFGATCAVKNGQAACECLQACSSLYDPVCGSD 505
R +P C+ + C C GA C C+C S
Sbjct: 1148 -----RCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQPGWS---------- 1192
Query: 506 GVTYGSACE--LEATACTLGREIQVARKGPCDRC------GQCRFGALCEAETGRCVCPS 557
G CE LE + E+ + + P C C G LC E R C +
Sbjct: 1193 ----GHHCENELECIPNSCVHELCMENE-PGSTCLCTPGFMTCSIGLLCGDEIRRITCLT 1247
Query: 558 ECVALAQPVCGSDGHTYPSECML 580
P+ PSE ++
Sbjct: 1248 PIFQRTDPISTQTYTIPPSETLV 1270
Score = 33.1 bits (74), Expect = 2.9
Identities = 15/55 (27%), Positives = 29/55 (52%), Gaps = 4/55 (7%)
Query: 1808 VDVTSFAGHPCTRASG----HPCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVE 1858
V ++ + G+ C + S +PC N ++C +Y C C G++G +C + + E
Sbjct: 758 VCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINE 812
Score = 33.1 bits (74), Expect = 2.9
Identities = 15/45 (33%), Positives = 19/45 (42%), Gaps = 4/45 (8%)
Query: 1813 FAGHPC----TRASGHPCLNGASCVPREAAYVCLCPGGFSGPHCE 1853
F+G C S PC N +CV + C C + GP CE
Sbjct: 920 FSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCE 964
Score = 32.7 bits (73), Expect = 3.7
Identities = 14/38 (36%), Positives = 18/38 (47%)
Query: 1819 TRASGHPCLNGASCVPREAAYVCLCPGGFSGPHCEKGL 1856
T P N A+C E Y C C GF+ +CEK +
Sbjct: 372 TSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAI 409
Score = 32.7 bits (73), Expect = 3.7
Identities = 15/35 (42%), Positives = 18/35 (51%), Gaps = 2/35 (5%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCE 1367
C S+PC + GTC D L F C+C G CE
Sbjct: 932 CSSEPCKNNGTCVD--LTNRFFCNCEPEYHGPFCE 964
Score = 32.3 bits (72), Expect = 4.9
Identities = 17/50 (34%), Positives = 24/50 (48%), Gaps = 8/50 (16%)
Query: 1813 FAGHPCTR---ASGHPCLNGASCVPR-----EAAYVCLCPGGFSGPHCEK 1854
F+G C S PC N SC+ + E AY C+C F+G +C +
Sbjct: 206 FSGKYCQELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSE 255
>gi|14211536 neurexin 2 isoform alpha-1 precursor [Homo sapiens]
Length = 1712
Score = 167 bits (423), Expect = 1e-40
Identities = 195/671 (29%), Positives = 284/671 (42%), Gaps = 104/671 (15%)
Query: 1396 LALEFRALEPQGLLLYNGNARGKDFLALALLDGRVQLRFDTGSG-PAVLTSAVPVEPGQW 1454
L+ R + LLLY + DFL L L+DGR++LRF PA L PV +W
Sbjct: 53 LSFSLRTNATRALLLYLDDGGDCDFLELLLVDGRLRLRFTLSCAEPATLQLDTPVADDRW 112
Query: 1455 HRLELSRHWRRGTLSVDGETPVLGESPSGTDGLNLDTDLFVGGVPED--QAAVALERTFV 1512
H + L+R RR L+VDGE E S + + +DLFVGG+P D +A+ L
Sbjct: 113 HMVLLTRDARRTALAVDGEARA-AEVRSKRREMQVASDLFVGGIPPDVRLSALTLSTVKY 171
Query: 1513 GAGLRGCIRLLDVNNQRLELGIGPGAATRGSGV-GECGDHPCLP--NPCHGGAPCQNLEA 1569
RG + L+LG P A G+ G D C P NPC G C L
Sbjct: 172 EPPFRGLL-------ANLKLGERPPALLGSQGLRGATADPLCAPARNPCANGGLCTVLAP 224
Query: 1570 GRFHCQCP-PGRVGPTCADEKSPCQPNPCHGAAPCRV----LPEGGAQCECPLGREGTFC 1624
G C C G G C++E+ P + P H V EGGA G G
Sbjct: 225 GEVGCDCSHTGFGGKFCSEEEHPME-GPAHLTLNSEVGSLLFSEGGA----GRGGAGDVH 279
Query: 1625 QTASGQDGSGPFLADFNGFSHLELRGLHTFARDLGEKMALEVVFLARGPSGLLLYNGQKT 1684
Q G++ F+A F G H + +++ L L R +GL+L+ G+
Sbjct: 280 QPTKGKE---EFVATFKGNEFFCYDLSHNPIQSSTDEITLAFRTLQR--NGLMLHTGK-- 332
Query: 1685 DGKGDFVSLALRDRRLEFRYDLGKGA--AVIRSREPV----TLGAWTRVSLERNGRKGA- 1737
D+V+L+L+ + +LG GA A++ EPV AW V + RN R+ A
Sbjct: 333 --SADYVNLSLKSGAVWLVINLGSGAFEALV---EPVNGKFNDNAWHDVRVTRNLRQHAG 387
Query: 1738 --------------LRVGDGPRVLGESPVPHTVLNLKEPLYVGGAPDFSKLARAAAVSSG 1783
+ V G + +T+L + Y+GG+P+ + L + VS+
Sbjct: 388 IGHAMVNKLHYLVTISVDGILTTTGYTQEDYTMLGSDDFFYIGGSPNTADLP-GSPVSNN 446
Query: 1784 FDGAIQLVSLGGRQLLTPEHVLRQVDVTSFA--GHPCTRASGHPCLNGASCVPREAAYVC 1841
F G ++ V +++++ A G P + G R
Sbjct: 447 FMGCLKDVVYKNNDF--------KLELSRLAKEGDPKMKLQGDLSF-------RCEDVAA 491
Query: 1842 LCPGGFSGPHCEKGLVEKSAGDVDTLAFDGRTFVEYLNAVTESEKALQSNHFELSLRTEA 1901
L P F P L SA +++ D RT TE L F R
Sbjct: 492 LDPVTFESPEAFVALPRWSAKRTGSISLDFRT--------TEPNGLLL---FSQGRRAGG 540
Query: 1902 TQGLVLWSGKATERADYVALAIVDGHLQLSYNLGSQPVVLR-STVPVNTNRWLRVVAHRE 1960
G S + +RADY A+ ++DGHL L ++GS + LR S+ VN W V R+
Sbjct: 541 GAG----SHSSAQRADYFAMELLDGHLYLLLDMGSGGIKLRASSRKVNDGEWCHVDFQRD 596
Query: 1961 QREGSLQVGNEAP---VTGSSPLGATQLDTDGALWLGGLPE-----LPVGPAL-PKAYGT 2011
R+GS+ V + + TG S + LD + L+LGGLPE LP+ P + A
Sbjct: 597 GRKGSISVNSRSTPFLATGDSEI----LDLESELYLGGLPEGGRVDLPLPPEVWTAALRA 652
Query: 2012 GFVGCLRDVVV 2022
G+VGC+RD+ +
Sbjct: 653 GYVGCVRDLFI 663
Score = 89.7 bits (221), Expect = 3e-17
Identities = 75/257 (29%), Positives = 115/257 (44%), Gaps = 17/257 (6%)
Query: 1339 FHGGTCQDWALGGGFT-CSCPAGRGGAVCEKVLGAPVPAFEGRSFLAFPTLRAYHTLRLA 1397
F+G D G T C A G ++ PV S+LA TL+AY ++ L
Sbjct: 887 FNGQPYMDQCKDGDITYCELNARFG---LRAIVADPVTFKSRSSYLALATLQAYASMHLF 943
Query: 1398 LEFRALEPQGLLLYNGNARGKDFLALALLDGRVQLRFDTGSGPAVL--TSAVPVEPGQWH 1455
+F+ P GLLL+N + G DF+ + L+ G + FD G+GP+++ S PV QWH
Sbjct: 944 FQFKTTAPDGLLLFN-SGNGNDFIVIELVKGYIHYVFDLGNGPSLMKGNSDKPVNDNQWH 1002
Query: 1456 RLELSRH-WRRGTLSVDGETPVLGESPSGTDGLNLDTDLFVGGVPEDQAAVALERTFVGA 1514
+ +SR TL +D T + + +G L+L +L++GG+ ++ + +
Sbjct: 1003 NVVVSRDPGNVHTLKIDSRT--VTQHSNGARNLDLKGELYIGGLSKNMFSNLPKLVASRD 1060
Query: 1515 GLRGCIRLLDVNNQRLELGIGPGAATRGSGVGECGDHP---CLPNPCHGGAPCQNLEAGR 1571
G +GC+ +D+N + +L I G C D P C C C G
Sbjct: 1061 GFQGCLASVDLNGRLPDL-IADALHRIGQVERGC-DGPSTTCTEESCANQGVCLQQWDG- 1117
Query: 1572 FHCQCP-PGRVGPTCAD 1587
F C C GP C D
Sbjct: 1118 FTCDCTMTSYGGPVCND 1134
Score = 89.4 bits (220), Expect = 3e-17
Identities = 79/248 (31%), Positives = 116/248 (46%), Gaps = 29/248 (11%)
Query: 1366 CEKVLGAPVPAFEG-RSFLAFPTLRAYHTLRLALEFRALEPQGLLLY------------N 1412
CE V FE +F+A P A T ++L+FR EP GLLL+ +
Sbjct: 486 CEDVAALDPVTFESPEAFVALPRWSAKRTGSISLDFRTTEPNGLLLFSQGRRAGGGAGSH 545
Query: 1413 GNARGKDFLALALLDGRVQLRFDTGSGPAVL-TSAVPVEPGQWHRLELSRHWRRGTLSVD 1471
+A+ D+ A+ LLDG + L D GSG L S+ V G+W ++ R R+G++SV+
Sbjct: 546 SSAQRADYFAMELLDGHLYLLLDMGSGGIKLRASSRKVNDGEWCHVDFQRDGRKGSISVN 605
Query: 1472 G-ETPVLGESPSGTDGLNLDTDLFVGGVPE-DQAAVALERTFVGAGLR----GCIRLLDV 1525
TP L S + L+L+++L++GG+PE + + L A LR GC+R L +
Sbjct: 606 SRSTPFLATGDS--EILDLESELYLGGLPEGGRVDLPLPPEVWTAALRAGYVGCVRDLFI 663
Query: 1526 NNQRLELGIGPGAATRGSGVGE-CGDH---PCLPNPCHGGAPCQNLEAGRFHCQC-PPGR 1580
+ + +L G A GV C C PC G C+ RF C C G
Sbjct: 664 DGRSRDLR-GLAEAQGAVGVAPFCSRETLKQCASAPCRNGGVCRE-GWNRFICDCIGTGF 721
Query: 1581 VGPTCADE 1588
+G C E
Sbjct: 722 LGRVCERE 729
Score = 86.7 bits (213), Expect = 2e-16
Identities = 119/431 (27%), Positives = 161/431 (37%), Gaps = 79/431 (18%)
Query: 1654 FARDLGEKMALEVVFLAR--GPSGLLLYNGQKTDGKGDFVSLALRDRRLEFRYDLGKGA- 1710
+AR G + E+ F R LLLY G DF+ L L D RL R+ L
Sbjct: 41 YARWAGAASSGELSFSLRTNATRALLLYLDD--GGDCDFLELLLVDGRLRLRFTLSCAEP 98
Query: 1711 AVIRSREPVTLGAWTRVSLERNGRKGALRVGDGPRVLGESPVPHTVLNLKEPLYVGGAPD 1770
A ++ PV W V L R+ R+ AL V DG E + + L+VGG P
Sbjct: 99 ATLQLDTPVADDRWHMVLLTRDARRTALAV-DGEARAAEVRSKRREMQVASDLFVGGIPP 157
Query: 1771 FSKLAR----AAAVSSGFDGAIQLVSLGGRQLLTPEHVLRQVDVTSFAGHPCTRASGHPC 1826
+L+ F G + + LG R P +L + P + +PC
Sbjct: 158 DVRLSALTLSTVKYEPPFRGLLANLKLGER----PPALLGSQGLRGATADPLCAPARNPC 213
Query: 1827 LNGASCVPREAAYV-CLCPG-GFSGPHC-------------------------EKGLVEK 1859
NG C V C C GF G C E G
Sbjct: 214 ANGGLCTVLAPGEVGCDCSHTGFGGKFCSEEEHPMEGPAHLTLNSEVGSLLFSEGGAGRG 273
Query: 1860 SAGDVD---------TLAFDGRTFVEYLNAVTESEKALQSNHFELSL--RTEATQGLVLW 1908
AGDV F G F Y S +QS+ E++L RT GL+L
Sbjct: 274 GAGDVHQPTKGKEEFVATFKGNEFFCY----DLSHNPIQSSTDEITLAFRTLQRNGLMLH 329
Query: 1909 SGKATERADYVALAIVDGHLQLSYNLGS---QPVVLRSTVPVNTNRW--LRVVAHREQRE 1963
+GK+ ADYV L++ G + L NLGS + +V N N W +RV + Q
Sbjct: 330 TGKS---ADYVNLSLKSGAVWLVINLGSGAFEALVEPVNGKFNDNAWHDVRVTRNLRQHA 386
Query: 1964 G-------------SLQVGNEAPVTGSSPLGATQLDTDGALWLGGLPELPVGPALPKAYG 2010
G ++ V TG + T L +D ++GG P P P
Sbjct: 387 GIGHAMVNKLHYLVTISVDGILTTTGYTQEDYTMLGSDDFFYIGGSPNTADLPGSP--VS 444
Query: 2011 TGFVGCLRDVV 2021
F+GCL+DVV
Sbjct: 445 NNFMGCLKDVV 455
Score = 83.6 bits (205), Expect = 2e-15
Identities = 84/342 (24%), Positives = 142/342 (41%), Gaps = 50/342 (14%)
Query: 1663 ALEVVFLARGPSGLLLYNGQKTDGKG----------DFVSLALRDRRLEFRYDLGKGAAV 1712
++ + F P+GLLL++ + G G D+ ++ L D L D+G G
Sbjct: 516 SISLDFRTTEPNGLLLFSQGRRAGGGAGSHSSAQRADYFAMELLDGHLYLLLDMGSGGIK 575
Query: 1713 IR-SREPVTLGAWTRVSLERNGRKGALRVGDGPR---VLGESPVPHTVLNLKEPLYVGGA 1768
+R S V G W V +R+GRKG++ V G+S +L+L+ LY+GG
Sbjct: 576 LRASSRKVNDGEWCHVDFQRDGRKGSISVNSRSTPFLATGDS----EILDLESELYLGGL 631
Query: 1769 PDFSKL-------ARAAAVSSGFDGAIQLVSLGG--RQLLTPEHVLRQVDVTSFAGHPCT 1819
P+ ++ AA+ +G+ G ++ + + G R L V V F
Sbjct: 632 PEGGRVDLPLPPEVWTAALRAGYVGCVRDLFIDGRSRDLRGLAEAQGAVGVAPFCSRETL 691
Query: 1820 R-ASGHPCLNGASCVPREAAYVCLCPG-GFSGPHCEKGLVEKSAGDVDTLAFDGRTFVEY 1877
+ + PC NG C ++C C G GF G CE+ + L++DG Y
Sbjct: 692 KQCASAPCRNGGVCREGWNRFICDCIGTGFLGRVCER--------EATVLSYDGSM---Y 740
Query: 1878 LNAVTESEKALQSNHFELSLRTEATQGLVLWSGKATERADYVALAIVDGHLQLSYNL--- 1934
+ + + ++ L ++ GL++ + + E AD + L + G ++L+ NL
Sbjct: 741 MKIMLPNAMHTEAEDVSLRFMSQRAYGLMM-ATTSRESADTLRLELDGGQMKLTVNLDCL 799
Query: 1935 ------GSQPVVLRSTVPVNTNRWLRVVAHREQREGSLQVGN 1970
P L + +N N W V R + L V N
Sbjct: 800 RVGCAPSKGPETLFAGHKLNDNEWHTVRVVRRGKSLQLSVDN 841
Score = 68.9 bits (167), Expect = 5e-11
Identities = 85/347 (24%), Positives = 137/347 (39%), Gaps = 29/347 (8%)
Query: 1644 SHLELRGLHTFARDLGEKMALEVVFLARGPSGLLLYNGQKTDGKG-DFVSLALRDRRLEF 1702
S+L L L +A M L F P GLLL+N G G DF+ + L + +
Sbjct: 927 SYLALATLQAYA-----SMHLFFQFKTTAPDGLLLFNS----GNGNDFIVIELVKGYIHY 977
Query: 1703 RYDLGKGAAVIR--SREPVTLGAWTRVSLERN-GRKGALRVGDGPRVLGESPVPHTVLNL 1759
+DLG G ++++ S +PV W V + R+ G L++ R + + L+L
Sbjct: 978 VFDLGNGPSLMKGNSDKPVNDNQWHNVVVSRDPGNVHTLKIDS--RTVTQHSNGARNLDL 1035
Query: 1760 KEPLYVGGAPD--FSKLARAAAVSSGFDGAIQLVSLGGR-QLLTPEHVLRQVDVTSFAGH 1816
K LY+GG FS L + A GF G + V L GR L + + R V
Sbjct: 1036 KGELYIGGLSKNMFSNLPKLVASRDGFQGCLASVDLNGRLPDLIADALHRIGQVERGCDG 1095
Query: 1817 PCTRASGHPCLNGASCVPREAAYVCLCP-GGFSGPHCEKGLVEKSAGDVDTLAFDGRTFV 1875
P T + C N C+ + + C C + GP C G G +
Sbjct: 1096 PSTTCTEESCANQGVCLQQWDGFTCDCTMTSYGGPVCNDPGTTYIFG-------KGGALI 1148
Query: 1876 EYLNAVTESEKALQSNHFELSLRTEATQGLVLWSGKATERADYVALAIVDGHLQLSYNLG 1935
Y + + + + T +++ A+ DY+ L I G + + +N+G
Sbjct: 1149 TY-TWPPNDRPSTRMDRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHIDQGTVGVIFNVG 1207
Query: 1936 SQPVVL-RSTVPVNTNRWLRVVAHREQREGSLQVGNEAPVTGSSPLG 1981
+ + + V+ ++ V R +LQV + PV P G
Sbjct: 1208 TDDITIDEPNAIVSDGKYHVVRFTRSGGNATLQV-DSWPVNERYPAG 1253
Score = 57.8 bits (138), Expect = 1e-07
Identities = 51/170 (30%), Positives = 76/170 (44%), Gaps = 17/170 (10%)
Query: 1887 ALQSNHFELSLRTEATQGLVLWSGKATERADYVALAIVDGHLQLSYNLG-SQPVVLRSTV 1945
A S SLRT AT+ L+L+ + D++ L +VDG L+L + L ++P L+
Sbjct: 47 AASSGELSFSLRTNATRALLLYLDDGGD-CDFLELLLVDGRLRLRFTLSCAEPATLQLDT 105
Query: 1946 PVNTNRWLRVVAHREQREGSLQVGNEAPVTG-SSPLGATQLDTDGALWLGGLP---ELPV 2001
PV +RW V+ R+ R +L V EA S Q+ +D L++GG+P L
Sbjct: 106 PVADDRWHMVLLTRDARRTALAVDGEARAAEVRSKRREMQVASD--LFVGGIPPDVRLSA 163
Query: 2002 GPALPKAYGTGFVGCLRDVVVGRHPLHLL---------EDAVTKPELRPC 2042
Y F G L ++ +G P LL D + P PC
Sbjct: 164 LTLSTVKYEPPFRGLLANLKLGERPPALLGSQGLRGATADPLCAPARNPC 213
Score = 56.6 bits (135), Expect = 2e-07
Identities = 46/168 (27%), Positives = 73/168 (43%), Gaps = 18/168 (10%)
Query: 1320 GRRPPAPQQPPKPCDSQPCFHGGTCQD-WALGGGFTCSC-PAGRGGAVCEKVLGAPVPAF 1377
G P ++ K C S PC +GG C++ W F C C G G VCE+ A V ++
Sbjct: 681 GVAPFCSRETLKQCASAPCRNGGVCREGW---NRFICDCIGTGFLGRVCER--EATVLSY 735
Query: 1378 EGRSFLAFPTLRAYHTLR--LALEFRALEPQGLLLYNGNARGKDFLALALLDGRVQLRFD 1435
+G ++ A HT ++L F + GL++ + D L L L G+++L +
Sbjct: 736 DGSMYMKIMLPNAMHTEAEDVSLRFMSQRAYGLMMATTSRESADTLRLELDGGQMKLTVN 795
Query: 1436 ---------TGSGPAVLTSAVPVEPGQWHRLELSRHWRRGTLSVDGET 1474
GP L + + +WH + + R + LSVD T
Sbjct: 796 LDCLRVGCAPSKGPETLFAGHKLNDNEWHTVRVVRRGKSLQLSVDNVT 843
Score = 33.1 bits (74), Expect = 2.9
Identities = 20/60 (33%), Positives = 25/60 (41%), Gaps = 5/60 (8%)
Query: 233 RIRLLSRGPCGSRDPCSNVTCSFGSTCARSADGLTASCLCPATCRGAPEGTVCGSDGADY 292
RI + RG G C+ +C+ C + DG T C C T G P VC G Y
Sbjct: 1085 RIGQVERGCDGPSTTCTEESCANQGVCLQQWDGFT--CDCTMTSYGGP---VCNDPGTTY 1139
>gi|21166380 neurexin 2 isoform alpha-2 precursor [Homo sapiens]
Length = 1642
Score = 162 bits (410), Expect = 3e-39
Identities = 187/660 (28%), Positives = 275/660 (41%), Gaps = 113/660 (17%)
Query: 1396 LALEFRALEPQGLLLYNGNARGKDFLALALLDGRVQLRFDTGSG-PAVLTSAVPVEPGQW 1454
L+ R + LLLY + DFL L L+DGR++LRF PA L PV +W
Sbjct: 53 LSFSLRTNATRALLLYLDDGGDCDFLELLLVDGRLRLRFTLSCAEPATLQLDTPVADDRW 112
Query: 1455 HRLELSRHWRRGTLSVDGETPVLGESPSGTDGLNLDTDLFVGGVPED--QAAVALERTFV 1512
H + L+R RR L+VDGE E S + + +DLFVGG+P D +A+ L
Sbjct: 113 HMVLLTRDARRTALAVDGEARA-AEVRSKRREMQVASDLFVGGIPPDVRLSALTLSTVKY 171
Query: 1513 GAGLRGCIRLLDVNNQRLELGIGPGAATRGSGV-GECGDHPCLP--NPCHGGAPCQNLEA 1569
RG + L+LG P A G+ G D C P NPC G C L
Sbjct: 172 EPPFRGLL-------ANLKLGERPPALLGSQGLRGATADPLCAPARNPCANGGLCTVLAP 224
Query: 1570 GRFHCQCP-PGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQCECPLGREGTFCQTAS 1628
G C C G G C++E+ P + P H
Sbjct: 225 GEVGCDCSHTGFGGKFCSEEEHPME-GPAH---------------------------LTL 256
Query: 1629 GQDGSGPFLADFNGFSHLELRGLHTFARDLGEKMALEVVFLARGPSGLLLYNGQKTDGKG 1688
+G F+A F G H + +++ L L R +GL+L+ G+
Sbjct: 257 NSEGKEEFVATFKGNEFFCYDLSHNPIQSSTDEITLAFRTLQR--NGLMLHTGK----SA 310
Query: 1689 DFVSLALRDRRLEFRYDLGKGA--AVIRSREPV----TLGAWTRVSLERNGRKGA----- 1737
D+V+L+L+ + +LG GA A++ EPV AW V + RN R+ A
Sbjct: 311 DYVNLSLKSGAVWLVINLGSGAFEALV---EPVNGKFNDNAWHDVRVTRNLRQHAGIGHA 367
Query: 1738 ---LRVGDGPRVLGESPVPHTVLNLKEPLYVGGAPDFSKLARAAAVSSGFDGAIQLVSLG 1794
+ V G + +T+L + Y+GG+P+ + L + VS+ F G ++ V
Sbjct: 368 MVTISVDGILTTTGYTQEDYTMLGSDDFFYIGGSPNTADLP-GSPVSNNFMGCLKDVVYK 426
Query: 1795 GRQLLTPEHVLRQVDVTSFA--GHPCTRASGHPCLNGASCVPREAAYVCLCPGGFSGPHC 1852
+++++ A G P + G R L P F P
Sbjct: 427 NNDF--------KLELSRLAKEGDPKMKLQGDLSF-------RCEDVAALDPVTFESPEA 471
Query: 1853 EKGLVEKSAGDVDTLAFDGRTFVEYLNAVTESEKALQSNHFELSLRTEATQGLVLWSGKA 1912
L SA +++ D RT TE L F R G S +
Sbjct: 472 FVALPRWSAKRTGSISLDFRT--------TEPNGLLL---FSQGRRAGGGAG----SHSS 516
Query: 1913 TERADYVALAIVDGHLQLSYNLGSQPVVLR-STVPVNTNRWLRVVAHREQREGSLQVGNE 1971
+RADY A+ ++DGHL L ++GS + LR S+ VN W V R+ R+GS+ V +
Sbjct: 517 AQRADYFAMELLDGHLYLLLDMGSGGIKLRASSRKVNDGEWCHVDFQRDGRKGSISVNSR 576
Query: 1972 AP---VTGSSPLGATQLDTDGALWLGGLPE-----LPVGPAL-PKAYGTGFVGCLRDVVV 2022
+ TG S + LD + L+LGGLPE LP+ P + A G+VGC+RD+ +
Sbjct: 577 STPFLATGDSEI----LDLESELYLGGLPEGGRVDLPLPPEVWTAALRAGYVGCVRDLFI 632
Score = 123 bits (308), Expect = 2e-27
Identities = 174/704 (24%), Positives = 280/704 (39%), Gaps = 150/704 (21%)
Query: 1366 CEKVLGAPVPAFEG-RSFLAFPTLRAYHTLRLALEFRALEPQGLLLY------------N 1412
CE V FE +F+A P A T ++L+FR EP GLLL+ +
Sbjct: 455 CEDVAALDPVTFESPEAFVALPRWSAKRTGSISLDFRTTEPNGLLLFSQGRRAGGGAGSH 514
Query: 1413 GNARGKDFLALALLDGRVQLRFDTGSGPAVL-TSAVPVEPGQWHRLELSRHWRRGTLSVD 1471
+A+ D+ A+ LLDG + L D GSG L S+ V G+W ++ R R+G++SV+
Sbjct: 515 SSAQRADYFAMELLDGHLYLLLDMGSGGIKLRASSRKVNDGEWCHVDFQRDGRKGSISVN 574
Query: 1472 G-ETPVLGESPSGTDGLNLDTDLFVGGVPE-DQAAVALERTFVGAGLR----GCIRLLDV 1525
TP L S + L+L+++L++GG+PE + + L A LR GC+R L +
Sbjct: 575 SRSTPFLATGDS--EILDLESELYLGGLPEGGRVDLPLPPEVWTAALRAGYVGCVRDLFI 632
Query: 1526 NNQRLELGIGPGAATRGSGVGE-CGDH---PCLPNPCHGGAPCQNLEAGRFHCQC-PPGR 1580
+ + +L G A GV C C PC G C+ RF C C G
Sbjct: 633 DGRSRDLR-GLAEAQGAVGVAPFCSRETLKQCASAPCRNGGVCRE-GWNRFICDCIGTGF 690
Query: 1581 VGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQCECPLGREGTFCQTASGQDGSGPFLADF 1640
+G C RE T + +
Sbjct: 691 LGRVCE--------------------------------REAT--------------VLSY 704
Query: 1641 NGFSHLEL---RGLHTFARDLGEKMALEVVFLARGPSGLLLYNGQKTDGKGDFVSLALRD 1697
+G ++++ +HT A D+ + F+++ GL++ + D + L L
Sbjct: 705 DGSMYMKIMLPNAMHTEAEDVSLR------FMSQRAYGLMMATTSRE--SADTLRLELDG 756
Query: 1698 RRLEFRYDLGKGAAVIRSREPVTLGAWTRVSLERNGRKGALRVGDGPRVLGESPVPHTVL 1757
+++ +LGKG + + + W V + R G+ L V D V G+ H L
Sbjct: 757 GQMKLTVNLGKGPETLFAGHKLNDNEWHTVRVVRRGKSLQLSV-DNVTVEGQMAGAHMRL 815
Query: 1758 NLKEPLYVGGAPDFSKLARAAAVSSGFDGAIQLVSLGGRQLLTPEHVLRQVDVTSFAGHP 1817
+ +G + +S + P + + + F G P
Sbjct: 816 EFHN------------------IETGIMTERRFIS------VVPSNFIGHLSGLVFNGQP 851
Query: 1818 CTRASGHPCLNGASCVPREAAYVCLCPGGFSGPHCE-KGLVEKSAGDVDTLAFDGRTFVE 1876
Y+ C G +CE A D + F R+
Sbjct: 852 ---------------------YMDQCKDG-DITYCELNARFGLRAIVADPVTFKSRS--S 887
Query: 1877 YLNAVTESEKALQSNHFELSLRTEATQGLVLW-SGKATERADYVALAIVDGHLQLSYNLG 1935
YL T +A S H +T A GL+L+ SG D++ + +V G++ ++LG
Sbjct: 888 YLALAT--LQAYASMHLFFQFKTTAPDGLLLFNSGNGN---DFIVIELVKGYIHYVFDLG 942
Query: 1936 SQPVVLR--STVPVNTNRWLRVVAHREQ-REGSLQVGNEAPVTGSSPLGATQLDTDGALW 1992
+ P +++ S PVN N+W VV R+ +L++ + S+ GA LD G L+
Sbjct: 943 NGPSLMKGNSDKPVNDNQWHNVVVSRDPGNVHTLKIDSRTVTQHSN--GARNLDLKGELY 1000
Query: 1993 LGGLPELPVGPALPK--AYGTGFVGCLRDVVVGRHPLHLLEDAV 2034
+GGL + + LPK A GF GCL V + L+ DA+
Sbjct: 1001 IGGLSK-NMFSNLPKLVASRDGFQGCLASVDLNGRLPDLIADAL 1043
Score = 94.7 bits (234), Expect = 8e-19
Identities = 117/400 (29%), Positives = 162/400 (40%), Gaps = 48/400 (12%)
Query: 1654 FARDLGEKMALEVVFLAR--GPSGLLLYNGQKTDGKGDFVSLALRDRRLEFRYDLGKGA- 1710
+AR G + E+ F R LLLY G DF+ L L D RL R+ L
Sbjct: 41 YARWAGAASSGELSFSLRTNATRALLLYLDD--GGDCDFLELLLVDGRLRLRFTLSCAEP 98
Query: 1711 AVIRSREPVTLGAWTRVSLERNGRKGALRVGDGPRVLGESPVPHTVLNLKEPLYVGGAPD 1770
A ++ PV W V L R+ R+ AL V DG E + + L+VGG P
Sbjct: 99 ATLQLDTPVADDRWHMVLLTRDARRTALAV-DGEARAAEVRSKRREMQVASDLFVGGIPP 157
Query: 1771 FSKLAR----AAAVSSGFDGAIQLVSLGGRQLLTPEHVLRQVDVTSFAGHPCTRASGHPC 1826
+L+ F G + + LG R P +L + P + +PC
Sbjct: 158 DVRLSALTLSTVKYEPPFRGLLANLKLGER----PPALLGSQGLRGATADPLCAPARNPC 213
Query: 1827 LNGASCVPREAAYV-CLCPG-GFSGPHCEKG---------LVEKSAGDVDTLA-FDGRTF 1874
NG C V C C GF G C + L S G + +A F G F
Sbjct: 214 ANGGLCTVLAPGEVGCDCSHTGFGGKFCSEEEHPMEGPAHLTLNSEGKEEFVATFKGNEF 273
Query: 1875 VEYLNAVTESEKALQSNHFELSL--RTEATQGLVLWSGKATERADYVALAIVDGHLQLSY 1932
Y S +QS+ E++L RT GL+L +GK+ ADYV L++ G + L
Sbjct: 274 FCY----DLSHNPIQSSTDEITLAFRTLQRNGLMLHTGKS---ADYVNLSLKSGAVWLVI 326
Query: 1933 NLGS---QPVVLRSTVPVNTNRW--LRVVAHREQREG------SLQVGNEAPVTGSSPLG 1981
NLGS + +V N N W +RV + Q G ++ V TG +
Sbjct: 327 NLGSGAFEALVEPVNGKFNDNAWHDVRVTRNLRQHAGIGHAMVTISVDGILTTTGYTQED 386
Query: 1982 ATQLDTDGALWLGGLPELPVGPALPKAYGTGFVGCLRDVV 2021
T L +D ++GG P P P F+GCL+DVV
Sbjct: 387 YTMLGSDDFFYIGGSPNTADLPGSP--VSNNFMGCLKDVV 424
Score = 89.7 bits (221), Expect = 3e-17
Identities = 75/257 (29%), Positives = 115/257 (44%), Gaps = 17/257 (6%)
Query: 1339 FHGGTCQDWALGGGFT-CSCPAGRGGAVCEKVLGAPVPAFEGRSFLAFPTLRAYHTLRLA 1397
F+G D G T C A G ++ PV S+LA TL+AY ++ L
Sbjct: 847 FNGQPYMDQCKDGDITYCELNARFG---LRAIVADPVTFKSRSSYLALATLQAYASMHLF 903
Query: 1398 LEFRALEPQGLLLYNGNARGKDFLALALLDGRVQLRFDTGSGPAVL--TSAVPVEPGQWH 1455
+F+ P GLLL+N + G DF+ + L+ G + FD G+GP+++ S PV QWH
Sbjct: 904 FQFKTTAPDGLLLFN-SGNGNDFIVIELVKGYIHYVFDLGNGPSLMKGNSDKPVNDNQWH 962
Query: 1456 RLELSRH-WRRGTLSVDGETPVLGESPSGTDGLNLDTDLFVGGVPEDQAAVALERTFVGA 1514
+ +SR TL +D T + + +G L+L +L++GG+ ++ + +
Sbjct: 963 NVVVSRDPGNVHTLKIDSRT--VTQHSNGARNLDLKGELYIGGLSKNMFSNLPKLVASRD 1020
Query: 1515 GLRGCIRLLDVNNQRLELGIGPGAATRGSGVGECGDHP---CLPNPCHGGAPCQNLEAGR 1571
G +GC+ +D+N + +L I G C D P C C C G
Sbjct: 1021 GFQGCLASVDLNGRLPDL-IADALHRIGQVERGC-DGPSTTCTEESCANQGVCLQQWDG- 1077
Query: 1572 FHCQCP-PGRVGPTCAD 1587
F C C GP C D
Sbjct: 1078 FTCDCTMTSYGGPVCND 1094
Score = 71.6 bits (174), Expect = 7e-12
Identities = 89/363 (24%), Positives = 145/363 (39%), Gaps = 31/363 (8%)
Query: 1644 SHLELRGLHTFARDLGEKMALEVVFLARGPSGLLLYNGQKTDGKG-DFVSLALRDRRLEF 1702
S+L L L +A M L F P GLLL+N G G DF+ + L + +
Sbjct: 887 SYLALATLQAYA-----SMHLFFQFKTTAPDGLLLFNS----GNGNDFIVIELVKGYIHY 937
Query: 1703 RYDLGKGAAVIR--SREPVTLGAWTRVSLERN-GRKGALRVGDGPRVLGESPVPHTVLNL 1759
+DLG G ++++ S +PV W V + R+ G L++ R + + L+L
Sbjct: 938 VFDLGNGPSLMKGNSDKPVNDNQWHNVVVSRDPGNVHTLKIDS--RTVTQHSNGARNLDL 995
Query: 1760 KEPLYVGGAPD--FSKLARAAAVSSGFDGAIQLVSLGGR-QLLTPEHVLRQVDVTSFAGH 1816
K LY+GG FS L + A GF G + V L GR L + + R V
Sbjct: 996 KGELYIGGLSKNMFSNLPKLVASRDGFQGCLASVDLNGRLPDLIADALHRIGQVERGCDG 1055
Query: 1817 PCTRASGHPCLNGASCVPREAAYVCLCP-GGFSGPHCEKGLVEKSAGDVDTLAFDGRTFV 1875
P T + C N C+ + + C C + GP C G G +
Sbjct: 1056 PSTTCTEESCANQGVCLQQWDGFTCDCTMTSYGGPVCNDPGTTYIFG-------KGGALI 1108
Query: 1876 EYLNAVTESEKALQSNHFELSLRTEATQGLVLWSGKATERADYVALAIVDGHLQLSYNLG 1935
Y + + + + T +++ A+ DY+ L I G + + +N+G
Sbjct: 1109 TY-TWPPNDRPSTRMDRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHIDQGTVGVIFNVG 1167
Query: 1936 SQPVVL-RSTVPVNTNRWLRVVAHREQREGSLQVGNEAPVTGSSPLG--ATQLDTDGALW 1992
+ + + V+ ++ V R +LQV + PV P G T ++ A+
Sbjct: 1168 TDDITIDEPNAIVSDGKYHVVRFTRSGGNATLQV-DSWPVNERYPAGRQLTIFNSQAAIK 1226
Query: 1993 LGG 1995
+GG
Sbjct: 1227 IGG 1229
Score = 66.6 bits (161), Expect = 2e-10
Identities = 48/160 (30%), Positives = 75/160 (46%), Gaps = 11/160 (6%)
Query: 1320 GRRPPAPQQPPKPCDSQPCFHGGTCQD-WALGGGFTCSCPAGRG--GAVCEKVLGAPVPA 1376
G P ++ K C S PC +GG C++ W F C C G G G VCE+ A V +
Sbjct: 650 GVAPFCSRETLKQCASAPCRNGGVCREGW---NRFICDC-IGTGFLGRVCERE--ATVLS 703
Query: 1377 FEGRSFLAFPTLRAYHTLR--LALEFRALEPQGLLLYNGNARGKDFLALALLDGRVQLRF 1434
++G ++ A HT ++L F + GL++ + D L L L G+++L
Sbjct: 704 YDGSMYMKIMLPNAMHTEAEDVSLRFMSQRAYGLMMATTSRESADTLRLELDGGQMKLTV 763
Query: 1435 DTGSGPAVLTSAVPVEPGQWHRLELSRHWRRGTLSVDGET 1474
+ G GP L + + +WH + + R + LSVD T
Sbjct: 764 NLGKGPETLFAGHKLNDNEWHTVRVVRRGKSLQLSVDNVT 803
Score = 57.8 bits (138), Expect = 1e-07
Identities = 51/170 (30%), Positives = 76/170 (44%), Gaps = 17/170 (10%)
Query: 1887 ALQSNHFELSLRTEATQGLVLWSGKATERADYVALAIVDGHLQLSYNLG-SQPVVLRSTV 1945
A S SLRT AT+ L+L+ + D++ L +VDG L+L + L ++P L+
Sbjct: 47 AASSGELSFSLRTNATRALLLYLDDGGD-CDFLELLLVDGRLRLRFTLSCAEPATLQLDT 105
Query: 1946 PVNTNRWLRVVAHREQREGSLQVGNEAPVTG-SSPLGATQLDTDGALWLGGLP---ELPV 2001
PV +RW V+ R+ R +L V EA S Q+ +D L++GG+P L
Sbjct: 106 PVADDRWHMVLLTRDARRTALAVDGEARAAEVRSKRREMQVASD--LFVGGIPPDVRLSA 163
Query: 2002 GPALPKAYGTGFVGCLRDVVVGRHPLHLL---------EDAVTKPELRPC 2042
Y F G L ++ +G P LL D + P PC
Sbjct: 164 LTLSTVKYEPPFRGLLANLKLGERPPALLGSQGLRGATADPLCAPARNPC 213
Score = 33.1 bits (74), Expect = 2.9
Identities = 20/60 (33%), Positives = 25/60 (41%), Gaps = 5/60 (8%)
Query: 233 RIRLLSRGPCGSRDPCSNVTCSFGSTCARSADGLTASCLCPATCRGAPEGTVCGSDGADY 292
RI + RG G C+ +C+ C + DG T C C T G P VC G Y
Sbjct: 1045 RIGQVERGCDGPSTTCTEESCANQGVCLQQWDGFT--CDCTMTSYGGP---VCNDPGTTY 1099
>gi|14149613 neurexin 1 isoform alpha1 precursor [Homo sapiens]
Length = 1477
Score = 137 bits (346), Expect = 8e-32
Identities = 180/703 (25%), Positives = 287/703 (40%), Gaps = 118/703 (16%)
Query: 1363 GAVCEKVLGAPVPAFEGRSFLAFPTLRAYHTLRLALEFRALEPQGLLLYNGNARGKDFLA 1422
G E G P EG+ + FP A ++ + + +GL+LY + DFL
Sbjct: 22 GCWAELGSGLEFPGAEGQ-WTRFPKWNACCESEMSFQLKTRSARGLVLYFDDEGFCDFLE 80
Query: 1423 LALL-DGRVQLRFDTGSG-PAVLTSAVPVEPGQWHRLELSRHWRRGTLSVDGETPVLGES 1480
L L GR+QL F PA L + PV G WH + + R +R TL +D E
Sbjct: 81 LILTRGGRLQLSFSIFCAEPATLLADTPVNDGAWHSVRIRRQFRNTTLFIDQVEAKWVEV 140
Query: 1481 PSGTDGLNLDTDLFVGGVPEDQAAVALERTFVGA----GLRGCIRLLDVNNQRLELGIGP 1536
S + + + LFVGG+P + A AL+ T +G IR + VN+ ++
Sbjct: 141 KSKRRDMTVFSGLFVGGLPPELRAAALKLTLASVREREPFKGWIRDVRVNSSQV------ 194
Query: 1537 GAATRGSGVGECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNP 1596
SG + D P PN GG+PC+ E G +
Sbjct: 195 --LPVDSGEVKLDDEP--PN-SGGGSPCEAGEEG----------------------EGGV 227
Query: 1597 CHGAAPCRVLPEGGAQCECP-LGREGTFC-QTASGQDGSGPFLADFNGFSH------LEL 1648
C C V+ + A C+C G G C Q + +G + G S
Sbjct: 228 CLNGGVCSVV-DDQAVCDCSRTGFRGKDCSQEDNNVEGLAHLMMGDQGKSKGKEEYIATF 286
Query: 1649 RGLHTFARDLGEKM------ALEVVFLARGPSGLLLYNGQKTDGKGDFVSLALRDRRLEF 1702
+G F DL + + + F +GL+L+ G+ D+V+LAL++ +
Sbjct: 287 KGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHTGK----SADYVNLALKNGAVSL 342
Query: 1703 RYDLGKGA--AVIRSREPV----TLGAWTRVSLERNGRKGA--------LRVGDGPRVLG 1748
+LG GA A++ EPV AW V + RN R+ + + V G
Sbjct: 343 VINLGSGAFEALV---EPVNGKFNDNAWHDVKVTRNLRQHSGIGHAMVTISVDGILTTTG 399
Query: 1749 ESPVPHTVLNLKEPLYVGGAPDFSKLARAAAVSSGFDGAIQLVSLGGRQLLTPEHVLRQV 1808
+ +T+L + YVGG+P + L + VS+ F G ++ V + V ++
Sbjct: 400 YTQEDYTMLGSDDFFYVGGSPSTADLP-GSPVSNNFMGCLKEV------VYKNNDVRLEL 452
Query: 1809 DVTSFAGHPCTRASG---HPCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVEKSAGDVD 1865
+ G P + G C N A+ L P F P L + +A
Sbjct: 453 SRLAKQGDPKMKIHGVVAFKCENVAT----------LDPITFETPESFISLPKWNAKKTG 502
Query: 1866 TLAFDGRTFVEYLNAVTESEKALQSNHFELSLRTEATQGLVLWSGKATERADYVALAIVD 1925
+++FD RT TE + +H + + +A ++ + D+ A+ ++D
Sbjct: 503 SISFDFRT--------TEPNGLILFSHGKPRHQKDAKHPQMI-------KVDFFAIEMLD 547
Query: 1926 GHLQLSYNLGSQPVVLRSTV-PVNTNRWLRVVAHREQREGSLQVGNEAPVTGSSPLGATQ 1984
GHL L ++GS + +++ + VN W V R+ R G++ V N ++P +
Sbjct: 548 GHLYLLLDMGSGTIKIKALLKKVNDGEWYHVDFQRDGRSGTISV-NTLRTPYTAPGESEI 606
Query: 1985 LDTDGALWLGGLPELPVGPALPKAYGT-----GFVGCLRDVVV 2022
LD D L+LGGLPE G P T G+VGC+RD+ +
Sbjct: 607 LDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFI 649
Score = 117 bits (292), Expect = 2e-25
Identities = 170/711 (23%), Positives = 283/711 (39%), Gaps = 155/711 (21%)
Query: 1366 CEKVLGAPVPAFEG-RSFLAFPTLRAYHTLRLALEFRALEPQGLLLYN-GNARGK----- 1418
CE V FE SF++ P A T ++ +FR EP GL+L++ G R +
Sbjct: 473 CENVATLDPITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKH 532
Query: 1419 ------DFLALALLDGRVQLRFDTGSGPAVLTSAVP-VEPGQWHRLELSRHWRRGTLSVD 1471
DF A+ +LDG + L D GSG + + + V G+W+ ++ R R GT+SV+
Sbjct: 533 PQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALLKKVNDGEWYHVDFQRDGRSGTISVN 592
Query: 1472 G-ETPVLGESPSGTDGLNLDTDLFVGGVPEDQAAVALER----TFVGAGLRGCIRLLDVN 1526
TP +P ++ L+LD +L++GG+PE++A + + G GCIR L ++
Sbjct: 593 TLRTPYT--APGESEILDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFID 650
Query: 1527 NQRLELG-IGPGAATRGSGVGECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTC 1585
Q ++ + +T G V P+C
Sbjct: 651 GQSKDIRQMAEVQSTAG--------------------------------------VKPSC 672
Query: 1586 ADEKS-PCQPNPCHGAAPCRVLPEGGAQ--CECP----LGREGTFCQTASGQDGSGPFLA 1638
+ E + PC NPC CR +G + C+C LGR T DGS
Sbjct: 673 SKETAKPCLSNPCKNNGMCR---DGWNRYVCDCSGTGYLGRSCEREATVLSYDGS----- 724
Query: 1639 DFNGFSHLELR-GLHTFARDLGEKMALEVVFLARGPSGLLLYNGQKTDGKGDFVSLALRD 1697
F ++L +HT A D+ + F ++ G+L+ + D + L L
Sbjct: 725 ---MFMKIQLPVVMHTEAEDVSLR------FRSQRAYGILMATTSR--DSADTLRLELDA 773
Query: 1698 RRLEFRYDL---------GKGAAVIRSREPVTLGAWTRVSLERNGRKGALRVGDGPRVLG 1748
R++ +L KG + + + W V + R G+ L V D + G
Sbjct: 774 GRVKLTVNLDCIRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTG 833
Query: 1749 ESPVPHTVLNLKEPLYVGGAPDFSKLARAAAVSSGFDGAIQLVSLGGRQLLTPEHVLRQV 1808
+ HT L + G + L ++V S F G +Q ++ G
Sbjct: 834 QMAGDHTRLEFHN-IETGIITERRYL---SSVPSNFIGHLQSLTFNG------------- 876
Query: 1809 DVTSFAGHPCTRASGHPCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVEKSAGDVDTLA 1868
AY+ LC G +CE + G + +A
Sbjct: 877 ----------------------------MAYIDLCKNG-DIDYCE---LNARFGFRNIIA 904
Query: 1869 FDGRTFVEYLNAVT-ESEKALQSNHFELSLRTEATQGLVLWSGKATERADYVALAIVDGH 1927
D TF + V + +A S H +T + GL+L++ + + D++ + +V G+
Sbjct: 905 -DPVTFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLILYN--SGDGNDFIVVELVKGY 961
Query: 1928 LQLSYNLGSQPVVLR--STVPVNTNRWLRVVAHREQREGSLQVGNEAPVTGSSPLGATQL 1985
L ++LG+ +++ S P+N N+W V+ R+ V + +T GA L
Sbjct: 962 LHYVFDLGNGANLIKGSSNKPLNDNQWHNVMISRD-TSNLHTVKIDTKITTQITAGARNL 1020
Query: 1986 DTDGALWLGGLPELPVGPALPKAYGT--GFVGCLRDVVVGRHPLHLLEDAV 2034
D L++GG+ + +LPK GF GCL V + L+ DA+
Sbjct: 1021 DLKSDLYIGGVAK-ETYKSLPKLVHAKEGFQGCLASVDLNGRLPDLISDAL 1070
Score = 87.4 bits (215), Expect = 1e-16
Identities = 90/410 (21%), Positives = 165/410 (40%), Gaps = 66/410 (16%)
Query: 1369 VLGAPVPAFEGRSFLAFPTLRAYHTLRLALEFRALEPQGLLLYNGNARGKDFLALALLDG 1428
++ PV S++A TL+AY ++ L +F+ GL+LYN + G DF+ + L+ G
Sbjct: 902 IIADPVTFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLILYN-SGDGNDFIVVELVKG 960
Query: 1429 RVQLRFDTGSGPAVL--TSAVPVEPGQWHRLELSRHWRR-GTLSVDGETPVLGESPSGTD 1485
+ FD G+G ++ +S P+ QWH + +SR T+ +D T + + +G
Sbjct: 961 YLHYVFDLGNGANLIKGSSNKPLNDNQWHNVMISRDTSNLHTVKID--TKITTQITAGAR 1018
Query: 1486 GLNLDTDLFVGGVPEDQAAVALERTFVGAGLRGCIRLLDVNNQRLELGIGPGAATRGSGV 1545
L+L +DL++GGV ++ + G +GC+ +D+N +
Sbjct: 1019 NLDLKSDLYIGGVAKETYKSLPKLVHAKEGFQGCLASVDLNGR----------------- 1061
Query: 1546 GECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRV 1605
LP+ C G++ C + CQ + C C +
Sbjct: 1062 --------LPDLISDALFCN-------------GQIERGCEGPSTTCQEDSCSNQGVC-L 1099
Query: 1606 LPEGGAQCECPL-GREGTFCQTASGQDGSGPFLADFNGFSHLELRGLHTFARDLGEKMAL 1664
G C+C + G C D ++ G G T+ ++ +
Sbjct: 1100 QQWDGFSCDCSMTSFSGPLC-----NDPGTTYIFSKGG-------GQITYKWPPNDRPST 1147
Query: 1665 EVVFLARGPSGL----LLYNGQKTDGKGDFVSLALRDRRLEFRYDLG-KGAAVIRSREPV 1719
LA G S + +L + G GD++ L + ++ ++++G A+ S +
Sbjct: 1148 RADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDIAIEESNAII 1207
Query: 1720 TLGAWTRVSLERNGRKGALRVGDGPRVLGESPVPH--TVLNLKEPLYVGG 1767
G + V R+G L+V P V+ P T+ N + + +GG
Sbjct: 1208 NDGKYHVVRFTRSGGNATLQVDSWP-VIERYPAGRQLTIFNSQATIIIGG 1256
Score = 65.9 bits (159), Expect = 4e-10
Identities = 78/347 (22%), Positives = 133/347 (38%), Gaps = 30/347 (8%)
Query: 1662 MALEVVFLARGPSGLLLYNGQKTDGKGDFVSLALRDRRLEFRYDLGKGAAVIR--SREPV 1719
M L F GL+LYN DG DF+ + L L + +DLG GA +I+ S +P+
Sbjct: 927 MHLFFQFKTTSLDGLILYNSG--DGN-DFIVVELVKGYLHYVFDLGNGANLIKGSSNKPL 983
Query: 1720 TLGAWTRVSLERNGRKGALRVGDGPRVLGESPVPHTVLNLKEPLYVGGA--PDFSKLARA 1777
W V + R+ V ++ + L+LK LY+GG + L +
Sbjct: 984 NDNQWHNVMISRD-TSNLHTVKIDTKITTQITAGARNLDLKSDLYIGGVAKETYKSLPKL 1042
Query: 1778 AAVSSGFDGAIQLVSLGGR-QLLTPEHVLRQVDVTSFAGHPCTRASGHPCLNGASCVPRE 1836
GF G + V L GR L + + + P T C N C+ +
Sbjct: 1043 VHAKEGFQGCLASVDLNGRLPDLISDALFCNGQIERGCEGPSTTCQEDSCSNQGVCLQQW 1102
Query: 1837 AAYVCLCP-GGFSGPHCEKG----LVEKSAGDVDTLAFDGRTFVEYLNAVTESEKALQSN 1891
+ C C FSGP C + K G + + +++
Sbjct: 1103 DGFSCDCSMTSFSGPLCNDPGTTYIFSKGGGQIT------------YKWPPNDRPSTRAD 1150
Query: 1892 HFELSLRTEATQGLVLWSGKATERADYVALAIVDGHLQLSYNLGSQPVVL-RSTVPVNTN 1950
+ T + +++ ++ DY+ L I G + + +N+G+ + + S +N
Sbjct: 1151 RLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDIAIEESNAIINDG 1210
Query: 1951 RWLRVVAHREQREGSLQVGNEAPVTGSSPLG--ATQLDTDGALWLGG 1995
++ V R +LQV + PV P G T ++ + +GG
Sbjct: 1211 KYHVVRFTRSGGNATLQV-DSWPVIERYPAGRQLTIFNSQATIIIGG 1256
Score = 63.5 bits (153), Expect = 2e-09
Identities = 52/207 (25%), Positives = 89/207 (42%), Gaps = 19/207 (9%)
Query: 1320 GRRPPAPQQPPKPCDSQPCFHGGTCQD-WALGGGFTCSCP-AGRGGAVCEKVLGAPVPAF 1377
G +P ++ KPC S PC + G C+D W + C C G G CE+ A V ++
Sbjct: 667 GVKPSCSKETAKPCLSNPCKNNGMCRDGW---NRYVCDCSGTGYLGRSCER--EATVLSY 721
Query: 1378 EGRSFLAFPTLRAYHTLR--LALEFRALEPQGLLLYNGNARGKDFLALALLDGRVQL--- 1432
+G F+ HT ++L FR+ G+L+ + D L L L GRV+L
Sbjct: 722 DGSMFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVKLTVN 781
Query: 1433 ------RFDTGSGPAVLTSAVPVEPGQWHRLELSRHWRRGTLSVDGETPVLGESPSGTDG 1486
++ GP L + + +WH + + R + L+VD + + G+
Sbjct: 782 LDCIRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGDHTR 841
Query: 1487 LNLDTDLFVGGVPEDQAAVALERTFVG 1513
L ++ G + E + ++ F+G
Sbjct: 842 LEFH-NIETGIITERRYLSSVPSNFIG 867
>gi|188528675 slit homolog 1 [Homo sapiens]
Length = 1534
Score = 137 bits (344), Expect = 1e-31
Identities = 109/347 (31%), Positives = 152/347 (43%), Gaps = 51/347 (14%)
Query: 1323 PPAPQQPPKPCDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEKVLGAPVPAFEGRSF 1382
PP P PC+ C +G C D G C C G GG CEK+L V + ++
Sbjct: 1121 PPHLPAPKSPCEGTECQNGANCVDQ--GNRPVCQCLPGFGGPECEKLLS--VNFVDRDTY 1176
Query: 1383 LAFPTLRAYHTLRLALEFRALEPQGLLLYNGNARGKDFLALALLDGRVQLRFDTGSGPA- 1441
L F L+ + + L+ E G+LLYNG+ D +A+ L G V++ +D GS P+
Sbjct: 1177 LQFTDLQNWPRANITLQVSTAEDNGILLYNGD---NDHIAVELYQGHVRVSYDPGSYPSS 1233
Query: 1442 VLTSAVPVEPGQWHRLELSRHWRRGTLSVDGETPVLGESPSGTDGLNLDTDLFVGGVPED 1501
+ SA + GQ+H +EL + LS+DG +P+ ++ LN + L+VGG+P D
Sbjct: 1234 AIYSAETINDGQFHTVELVAFDQMVNLSIDGGSPMTMDNFGKHYTLNSEAPLYVGGMPVD 1293
Query: 1502 --QAAVALERTFVGAGLRGCIRLLDVNNQ-------RLELGIGPGA-------------- 1538
AA L + G G GCIR L +NN+ +++ G+ PG
Sbjct: 1294 VNSAAFRLWQILNGTGFHGCIRNLYINNELQDFTKTQMKPGVVPGCEPCRKLYCLHGICQ 1353
Query: 1539 --ATRG-------SGVGECGDHPCLPNPCHG----GAPCQNLEAGRFHCQCPPGRVGPTC 1585
AT G VG D P PCHG C L+A + CQC G G C
Sbjct: 1354 PNATPGPMCHCEAGWVGLHCDQPA-DGPCHGHKCVHGQCVPLDALSYSCQCQDGYSGALC 1412
Query: 1586 ADE---KSPCQPNPC-HGAAPCRVLPEGGAQCECPLGREGTFCQTAS 1628
PC+ C HG C+ GA C C G G C+ S
Sbjct: 1413 NQAGALAEPCRGLQCLHG--HCQASGTKGAHCVCDPGFSGELCEQES 1457
Score = 77.0 bits (188), Expect = 2e-13
Identities = 66/234 (28%), Positives = 115/234 (49%), Gaps = 28/234 (11%)
Query: 1817 PCTRASGHPCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVEKSAGDVDTLAFDGRTFVE 1876
P + G C NGA+CV + VC C GF GP CEK L+ + D DT
Sbjct: 1127 PKSPCEGTECQNGANCVDQGNRPVCQCLPGFGGPECEK-LLSVNFVDRDT---------- 1175
Query: 1877 YLNAVTESEKALQSNHFELSLRTEATQGLVLWSGKATERADYVALAIVDGHLQLSYNLGS 1936
YL T+ + ++N L + T G++L++G D++A+ + GH+++SY+ GS
Sbjct: 1176 YLQ-FTDLQNWPRAN-ITLQVSTAEDNGILLYNGD----NDHIAVELYQGHVRVSYDPGS 1229
Query: 1937 QP-VVLRSTVPVNTNRWLRVVAHREQREGSLQVGNEAPVTGSSPLGATQLDTDGALWLGG 1995
P + S +N ++ V + +L + +P+T + L+++ L++GG
Sbjct: 1230 YPSSAIYSAETINDGQFHTVELVAFDQMVNLSIDGGSPMTMDNFGKHYTLNSEAPLYVGG 1289
Query: 1996 LPELPVGPALPKAY----GTGFVGCLRDVVVGRHPLHLLEDAVTKPELRPCPTP 2045
+P + V A + + GTGF GC+R++ + L+D TK +++P P
Sbjct: 1290 MP-VDVNSAAFRLWQILNGTGFHGCIRNLYINNE----LQD-FTKTQMKPGVVP 1337
Score = 74.3 bits (181), Expect = 1e-12
Identities = 95/379 (25%), Positives = 135/379 (35%), Gaps = 88/379 (23%)
Query: 1553 CLP--NPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCR------ 1604
C P NPC A C G C+C PG G C++ + C+ + C A C
Sbjct: 1047 CSPDLNPCQHEAQCVGTPDGP-RCECMPGYAGDNCSENQDDCRDHRCQNGAQCMDEVNSY 1105
Query: 1605 --VLPEG--GAQCECP-------LGREGTFCQTASG--QDGSGPFLADFNGFSHLELRGL 1651
+ EG G CE P EGT CQ + G+ P GF E L
Sbjct: 1106 SCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPVCQCLPGFGGPECEKL 1165
Query: 1652 HTFARDLGEKMALEVVFLARGP-------------SGLLLYNGQKTDGKGDFVSLALRDR 1698
+ + L+ L P +G+LLYNG D +++ L
Sbjct: 1166 LS-VNFVDRDTYLQFTDLQNWPRANITLQVSTAEDNGILLYNGD-----NDHIAVELYQG 1219
Query: 1699 RLEFRYDLGK-GAAVIRSREPVTLGAWTRVSLERNGRKGALRVGDGPRVLGESPVPHTVL 1757
+ YD G ++ I S E + G + V L + L + G + ++ H L
Sbjct: 1220 HVRVSYDPGSYPSSAIYSAETINDGQFHTVELVAFDQMVNLSIDGGSPMTMDNFGKHYTL 1279
Query: 1758 NLKEPLYVGGAP---------------------------------DFSKLARAAAVSSGF 1784
N + PLYVGG P DF+K V G
Sbjct: 1280 NSEAPLYVGGMPVDVNSAAFRLWQILNGTGFHGCIRNLYINNELQDFTKTQMKPGVVPGC 1339
Query: 1785 DGAIQLVSLGG--RQLLTPEHVLR------QVDVTSFAGHPCTRASGHPCLNGASCVPRE 1836
+ +L L G + TP + + A PC GH C++G CVP +
Sbjct: 1340 EPCRKLYCLHGICQPNATPGPMCHCEAGWVGLHCDQPADGPC---HGHKCVHG-QCVPLD 1395
Query: 1837 A-AYVCLCPGGFSGPHCEK 1854
A +Y C C G+SG C +
Sbjct: 1396 ALSYSCQCQDGYSGALCNQ 1414
Score = 54.3 bits (129), Expect = 1e-06
Identities = 28/75 (37%), Positives = 31/75 (41%), Gaps = 3/75 (4%)
Query: 1553 CLPNPCHGGAPC--QNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGG 1610
C PC G C Q E F C CP G GPTC C + C C V G
Sbjct: 968 CSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVC-VDGVGN 1026
Query: 1611 AQCECPLGREGTFCQ 1625
C+CPL EG C+
Sbjct: 1027 YTCQCPLQYEGKACE 1041
Score = 53.1 bits (126), Expect = 3e-06
Identities = 59/209 (28%), Positives = 77/209 (36%), Gaps = 48/209 (22%)
Query: 750 CRGPTFAPLPPVAPLHCAQTPYGCCQDNITAARG---VGLAGCPS------------ACQ 794
C+GP + L C +P CQ+ T V CPS +C
Sbjct: 914 CQGPPTLAVQAKCDL-CLSSP---CQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCS 969
Query: 795 CNPHGSYGGTCDPATGQ-----CSCRPGVGGLRC----DRCEPGFWNFRGIVTDGRSGCT 845
P + GGTC G+ CSC G G C D C G+ DG T
Sbjct: 970 SGPCEN-GGTCHAQEGEDAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYT 1028
Query: 846 PCSCDPQGAVRDDCEQMTGLCS-----------CKPGVAGPKCGQCPDGRALGPAGCEAD 894
C C Q + CEQ+ LCS C GP+C +C G A D
Sbjct: 1029 -CQCPLQYEGKA-CEQLVDLCSPDLNPCQHEAQCVGTPDGPRC-ECMPGYAGDNCSENQD 1085
Query: 895 ASAPATCAEMRCEFGARCVEESGSAHCVC 923
C + RC+ GA+C++E S C+C
Sbjct: 1086 -----DCRDHRCQNGAQCMDEVNSYSCLC 1109
Score = 51.2 bits (121), Expect = 1e-05
Identities = 24/74 (32%), Positives = 26/74 (35%), Gaps = 2/74 (2%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGA- 1611
CL +PC C N + C CP G G C C PC C A
Sbjct: 929 CLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDAP 988
Query: 1612 -QCECPLGREGTFC 1624
C CP G EG C
Sbjct: 989 FTCSCPTGFEGPTC 1002
Score = 47.8 bits (112), Expect = 1e-04
Identities = 30/87 (34%), Positives = 36/87 (41%), Gaps = 9/87 (10%)
Query: 1540 TRGSGVGECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQP--NPC 1597
T G +C DH C +GG + G + CQCP G C C P NPC
Sbjct: 1001 TCGVNTDDCVDHAC----ANGGVCVDGV--GNYTCQCPLQYEGKACEQLVDLCSPDLNPC 1054
Query: 1598 HGAAPCRVLPEGGAQCECPLGREGTFC 1624
A C P+ G +CEC G G C
Sbjct: 1055 QHEAQCVGTPD-GPRCECMPGYAGDNC 1080
Score = 43.9 bits (102), Expect = 0.002
Identities = 55/243 (22%), Positives = 86/243 (35%), Gaps = 37/243 (15%)
Query: 199 KSPCPSVVAPVCGSDASTYSNECELQRAQCSQQRRIRLLSRGPCG-SRDPCSNVTCSFGS 257
++ C ++ C + + +++ E+ R C + R C S D CS+ C G
Sbjct: 923 QAKCDLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGR-----DCEVSLDSCSSGPCENGG 977
Query: 258 TC-ARSADGLTASCLCPA-----TC---------RGAPEGTVCGSDGADYPGEC--QLLR 300
TC A+ + +C CP TC G VC +Y +C Q
Sbjct: 978 TCHAQEGEDAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEG 1037
Query: 301 RACARQENVFKKFDGPCD---PCQGALPDPSRSCRVNPRTRRPEMLLRPESC---PARQA 354
+AC + ++ PC C G PD R C P + C +
Sbjct: 1038 KACEQLVDLCSPDLNPCQHEAQCVGT-PDGPR-CECMPGYAGDNCSENQDDCRDHRCQNG 1095
Query: 355 PVCGDDGVTYENDCVMGRSGAARGLLLQ-KVRSGQCQGRDQCPEPCRFNAVCLSRRGRPR 413
C D+ +Y C G SG + C+G + C+ A C+ + RP
Sbjct: 1096 AQCMDEVNSYSCLCAEGYSGQLCEIPPHLPAPKSPCEGTE-----CQNGANCVDQGNRPV 1150
Query: 414 CSC 416
C C
Sbjct: 1151 CQC 1153
Score = 41.6 bits (96), Expect = 0.008
Identities = 60/266 (22%), Positives = 89/266 (33%), Gaps = 81/266 (30%)
Query: 266 LTASCLCPATCRGAPEGTVCGSDGADYPG-ECQLLRRACARQENVFKKFDGPCDPCQGAL 324
L++ C TC P + + Y G +C++ +C+ GPC+
Sbjct: 930 LSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCS---------SGPCEN----- 975
Query: 325 PDPSRSCRVNPRTRRPEMLLRPESCPAR-QAPVCGDDGVTYENDCVMGRSGAARGLLLQK 383
+C P SCP + P CG + +DCV + A G+ +
Sbjct: 976 ---GGTCHAQEGEDAPFTC----SCPTGFEGPTCGVN----TDDCV-DHACANGGVCVDG 1023
Query: 384 VRSGQCQ------GR------DQCP---EPCRFNAVCLSRRGRPRCSCDRVTCDGAYRPV 428
V + CQ G+ D C PC+ A C+ PRC C P
Sbjct: 1024 VGNYTCQCPLQYEGKACEQLVDLCSPDLNPCQHEAQCVGTPDGPRCEC---------MPG 1074
Query: 429 CAQDGRTYDSDCWRQQAECRQQRA----------------IPSKHQGPCDQAP------- 465
A D +C Q +CR R + G + P
Sbjct: 1075 YAGD------NCSENQDDCRDHRCQNGAQCMDEVNSYSCLCAEGYSGQLCEIPPHLPAPK 1128
Query: 466 SPCLGVQCAFGATCAVKNGQAACECL 491
SPC G +C GA C + + C+CL
Sbjct: 1129 SPCEGTECQNGANCVDQGNRPVCQCL 1154
Score = 39.7 bits (91), Expect = 0.031
Identities = 40/172 (23%), Positives = 53/172 (30%), Gaps = 58/172 (33%)
Query: 803 GTC--DPA-TGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDPQGAVR-DD 858
GTC DP +C+C G G C+ C+ C+ G +
Sbjct: 938 GTCHNDPLEVYRCACPSGYKGRDCEV--------------SLDSCSSGPCENGGTCHAQE 983
Query: 859 CEQMTGLCSCKPGVAGPKCGQCPDGRALGPAGCEADASAPATCAEMRCEFGARCVEESGS 918
E CSC G GP CG D C + C G CV+ G+
Sbjct: 984 GEDAPFTCSCPTGFEGPTCGVNTDD-----------------CVDHACANGGVCVDGVGN 1026
Query: 919 AHCVCPMLTCPEANATKVCGSDGVTYGNECQLKTIACRQGLQISIQSLGPCQ 970
C CP+ Q + AC Q + + L PCQ
Sbjct: 1027 YTCQCPL-----------------------QYEGKACEQLVDLCSPDLNPCQ 1055
Score = 38.5 bits (88), Expect = 0.068
Identities = 21/59 (35%), Positives = 26/59 (44%), Gaps = 7/59 (11%)
Query: 1801 PEHVLRQVDVTSFAGHPCT----RASGHPCLNGASCVPRE---AAYVCLCPGGFSGPHC 1852
P V R + + G C S PC NG +C +E A + C CP GF GP C
Sbjct: 944 PLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTC 1002
Score = 37.7 bits (86), Expect = 0.12
Identities = 21/67 (31%), Positives = 27/67 (40%), Gaps = 3/67 (4%)
Query: 1569 AGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQCECPLGREGTFCQTAS 1628
A +F CQ PP D C +PC C P +C CP G +G C+ +
Sbjct: 909 AKKFECQGPPTLAVQAKCDL---CLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSL 965
Query: 1629 GQDGSGP 1635
SGP
Sbjct: 966 DSCSSGP 972
Score = 37.4 bits (85), Expect = 0.15
Identities = 17/35 (48%), Positives = 18/35 (51%), Gaps = 1/35 (2%)
Query: 1333 CDSQPCFHGGTCQ-DWALGGGFTCSCPAGRGGAVC 1366
C S PC +GGTC FTCSCP G G C
Sbjct: 968 CSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTC 1002
Score = 37.0 bits (84), Expect = 0.20
Identities = 53/250 (21%), Positives = 74/250 (29%), Gaps = 45/250 (18%)
Query: 615 AGQCVCPRCEHPPPGPVCGSDGVTYGSACELREAACLQ-------QTQIEEARAGPCEQA 667
A Q C C P C + G + E+ AC + ++ +GPCE
Sbjct: 921 AVQAKCDLCLSSP----CQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENG 976
Query: 668 ECGSGGSGSGEDG----DCEQELCRQRGGIWDEDSEDGPCVCDFSCQSVPGSPVCGSDGV 723
G+ + GED C G+ +D D C C G+ C
Sbjct: 977 --GTCHAQEGEDAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQ 1034
Query: 724 TYSTECELKKARCESQRGLY---VAAQGACRGPTFAPLPPVAPLHCAQTPYGC----CQD 776
CE C G GP +P A +C++ C CQ+
Sbjct: 1035 YEGKACEQLVDLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQN 1094
Query: 777 NITAARGVGLAGCPSA-------CQCNPH------------GSYGGTCDPATGQ--CSCR 815
V C A C+ PH G C + C C
Sbjct: 1095 GAQCMDEVNSYSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPVCQCL 1154
Query: 816 PGVGGLRCDR 825
PG GG C++
Sbjct: 1155 PGFGGPECEK 1164
Score = 36.6 bits (83), Expect = 0.26
Identities = 41/175 (23%), Positives = 56/175 (32%), Gaps = 40/175 (22%)
Query: 803 GTCDPATG---QCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDPQGAVRDDC 859
G C P C C G GL CD+ G C V C
Sbjct: 1350 GICQPNATPGPMCHCEAGWVGLHCDQPADG------------------PCHGHKCVHGQC 1391
Query: 860 EQMTGL---CSCKPGVAGPKCGQCPDGRALGPAGCEADASAPATCAEMRCEFGARCVEES 916
+ L C C+ G +G C Q AG A+ C ++C G +
Sbjct: 1392 VPLDALSYSCQCQDGYSGALCNQ---------AGALAEP-----CRGLQCLHGHCQASGT 1437
Query: 917 GSAHCVC-PMLTCPEANATKVCGSDGVTYGNECQLKTIACRQGLQIS-IQSLGPC 969
AHCVC P + C D V ++ Q C+ +S ++ G C
Sbjct: 1438 KGAHCVCDPGFSGELCEQESECRGDPVRDFHQVQRGYAICQTTRPLSWVECRGSC 1492
Score = 36.2 bits (82), Expect = 0.34
Identities = 62/245 (25%), Positives = 78/245 (31%), Gaps = 70/245 (28%)
Query: 533 PCDRCGQCRFGALCEAETGRCVCPSECVALAQPVCGSDGHTYPSECMLHVHACTHQISLH 592
PC G C L E RC CPS G G +C ++SL
Sbjct: 933 PCQNQGTCHNDPL---EVYRCACPS----------GYKGR----DC---------EVSLD 966
Query: 593 VASAGPCE---------------TCGDAVCAFGAVC--SAGQCVCPRCEHPPPGPVCGSD 635
S+GPCE TC G C + CV C + G VC
Sbjct: 967 SCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVNTDDCVDHACAN---GGVCVDG 1023
Query: 636 GVTYGSACELR--EAACLQQTQIEEARAGPCE------------QAECGSGGSG---SGE 678
Y C L+ AC Q + PC+ + EC G +G S
Sbjct: 1024 VGNYTCQCPLQYEGKACEQLVDLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSEN 1083
Query: 679 DGDCEQELCRQRGGIWDE-DSEDGPCVCDFS---CQSVPGSPVCGSDGVTYSTECELKKA 734
DC C+ DE +S C +S C+ P P S TEC+ A
Sbjct: 1084 QDDCRDHRCQNGAQCMDEVNSYSCLCAEGYSGQLCEIPPHLPAPKSP--CEGTECQ-NGA 1140
Query: 735 RCESQ 739
C Q
Sbjct: 1141 NCVDQ 1145
Score = 35.4 bits (80), Expect = 0.58
Identities = 55/241 (22%), Positives = 78/241 (32%), Gaps = 32/241 (13%)
Query: 444 QAECRQQRAIPSKHQGPCDQAPSPCLGVQCAFGATCAVKNGQAACECLQACSSLYDPVCG 503
QA+C + P ++QG C P CA +G +C + S C
Sbjct: 923 QAKCDLCLSSPCQNQGTCHNDPLEVY--------RCACPSGYKGRDCEVSLDSCSSGPCE 974
Query: 504 SDGVTYGSACELEATACTLGREIQVARKG-PCDRC--GQCRFGALCEAETGR--CVCPSE 558
+ G + E C+ + G D C C G +C G C CP +
Sbjct: 975 NGGTCHAQEGEDAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQ 1034
Query: 559 CVALAQPVCGSDGHTYPSECMLHVHACTHQISLHVASAGPCETCGDAVCAFGAVCSAGQ- 617
G C ++ C H+ GP C G CS Q
Sbjct: 1035 YE-------GKACEQLVDLCSPDLNPCQHEAQCVGTPDGPRCECMPGYA--GDNCSENQD 1085
Query: 618 -CVCPRCEHPPPGPVCGSDGVTYGSACELREAACLQQTQIE---EARAGPCEQAECGSGG 673
C RC++ G C + +Y C E Q +I A PCE EC +G
Sbjct: 1086 DCRDHRCQN---GAQCMDEVNSYSCLC--AEGYSGQLCEIPPHLPAPKSPCEGTECQNGA 1140
Query: 674 S 674
+
Sbjct: 1141 N 1141
Score = 35.0 bits (79), Expect = 0.75
Identities = 20/59 (33%), Positives = 26/59 (44%), Gaps = 5/59 (8%)
Query: 1811 TSFAGHPC----TRASGHPCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVEKSAGDVD 1865
T F G C H C NG CV Y C CP + G CE+ LV+ + D++
Sbjct: 995 TGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQ-LVDLCSPDLN 1052
Score = 34.3 bits (77), Expect = 1.3
Identities = 14/38 (36%), Positives = 19/38 (50%), Gaps = 2/38 (5%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEKVL 1370
C C +GG C D G +TC CP G CE+++
Sbjct: 1009 CVDHACANGGVCVDGV--GNYTCQCPLQYEGKACEQLV 1044
Score = 33.1 bits (74), Expect = 2.9
Identities = 21/58 (36%), Positives = 28/58 (48%), Gaps = 3/58 (5%)
Query: 1312 TTAPSRVPGRRPP--APQQPPKPCDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCE 1367
TT + + PP A Q C S PC + GTC + L + C+CP+G G CE
Sbjct: 906 TTPAKKFECQGPPTLAVQAKCDLCLSSPCQNQGTCHNDPLEV-YRCACPSGYKGRDCE 962
Score = 33.1 bits (74), Expect = 2.9
Identities = 18/47 (38%), Positives = 21/47 (44%), Gaps = 3/47 (6%)
Query: 1818 CTRASGHPCLNGASCV--PREAAYVCLCPGGFSGPHCEKGLVEKSAG 1862
C PC N +C P E Y C CP G+ G CE L S+G
Sbjct: 926 CDLCLSSPCQNQGTCHNDPLEV-YRCACPSGYKGRDCEVSLDSCSSG 971
>gi|208609951 neurexin 1 isoform alpha2 precursor [Homo sapiens]
Length = 1547
Score = 134 bits (336), Expect = 1e-30
Identities = 183/722 (25%), Positives = 292/722 (40%), Gaps = 116/722 (16%)
Query: 1363 GAVCEKVLGAPVPAFEGRSFLAFPTLRAYHTLRLALEFRALEPQGLLLYNGNARGKDFLA 1422
G E G P EG+ + FP A ++ + + +GL+LY + DFL
Sbjct: 22 GCWAELGSGLEFPGAEGQ-WTRFPKWNACCESEMSFQLKTRSARGLVLYFDDEGFCDFLE 80
Query: 1423 LALL-DGRVQLRFDTGSG-PAVLTSAVPVEPGQWHRLELSRHWRRGTLSVDGETPVLGES 1480
L L GR+QL F PA L + PV G WH + + R +R TL +D E
Sbjct: 81 LILTRGGRLQLSFSIFCAEPATLLADTPVNDGAWHSVRIRRQFRNTTLFIDQVEAKWVEV 140
Query: 1481 PSGTDGLNLDTDLFVGGVPEDQAAVALERTFVGA----GLRGCIRLLDVNNQRLELGIGP 1536
S + + + LFVGG+P + A AL+ T +G IR + VN+ ++
Sbjct: 141 KSKRRDMTVFSGLFVGGLPPELRAAALKLTLASVREREPFKGWIRDVRVNSSQV------ 194
Query: 1537 GAATRGSGVGECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEK-SPCQPN 1595
SG + D P PN GG+PC+ E G C G V D+ C
Sbjct: 195 --LPVDSGEVKLDDEP--PN-SGGGSPCEAGEEGEGGV-CLNGGVCSVVDDQAVCDCSRT 248
Query: 1596 PCHGAAPCRVLPEGGAQCECPL----GREGTFC---------QTASGQDGSGPFLADFNG 1642
G C + G QC P+ +G +C + + +G + G
Sbjct: 249 GFRG-KDCSQEIKFGLQCVLPVLLHDNDQGKYCCINTAKPLTEKDNNVEGLAHLMMGDQG 307
Query: 1643 FSH------LELRGLHTFARDLGEKM------ALEVVFLARGPSGLLLYNGQKTDGKGDF 1690
S +G F DL + + + F +GL+L+ G+ D+
Sbjct: 308 KSKGKEEYIATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHTGK----SADY 363
Query: 1691 VSLALRDRRLEFRYDLGKGA--AVIRSREPV----TLGAWTRVSLERNGRKGA------- 1737
V+LAL++ + +LG GA A++ EPV AW V + RN R+ +
Sbjct: 364 VNLALKNGAVSLVINLGSGAFEALV---EPVNGKFNDNAWHDVKVTRNLRQHSGIGHAMV 420
Query: 1738 --------LRVGDGPRVLGESPVPHTVLNLKEPLYVGGAPDFSKLARAAAVSSGFDGAIQ 1789
+ V G + +T+L + YVGG+P + L + VS+ F G ++
Sbjct: 421 NKLHCSVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLP-GSPVSNNFMGCLK 479
Query: 1790 LVSLGGRQLLTPEHVLRQVDVTSFAGHPCTRASG---HPCLNGASCVPREAAYVCLCPGG 1846
V + V ++ + G P + G C N A+ L P
Sbjct: 480 EV------VYKNNDVRLELSRLAKQGDPKMKIHGVVAFKCENVAT----------LDPIT 523
Query: 1847 FSGPHCEKGLVEKSAGDVDTLAFDGRTFVEYLNAVTESEKALQSNHFELSLRTEATQGLV 1906
F P L + +A +++FD RT TE + +H + + +A +
Sbjct: 524 FETPESFISLPKWNAKKTGSISFDFRT--------TEPNGLILFSHGKPRHQKDAKHPQM 575
Query: 1907 LWSGKATERADYVALAIVDGHLQLSYNLGSQPVVLRSTV-PVNTNRWLRVVAHREQREGS 1965
+ + D+ A+ ++DGHL L ++GS + +++ + VN W V R+ R G+
Sbjct: 576 I-------KVDFFAIEMLDGHLYLLLDMGSGTIKIKALLKKVNDGEWYHVDFQRDGRSGT 628
Query: 1966 LQVGNEAPVTGSSPLGATQLDTDGALWLGGLPELPVGPALPKAYGT-----GFVGCLRDV 2020
+ V N ++P + LD D L+LGGLPE G P T G+VGC+RD+
Sbjct: 629 ISV-NTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVGCIRDL 687
Query: 2021 VV 2022
+
Sbjct: 688 FI 689
Score = 117 bits (292), Expect = 2e-25
Identities = 170/711 (23%), Positives = 283/711 (39%), Gaps = 155/711 (21%)
Query: 1366 CEKVLGAPVPAFEG-RSFLAFPTLRAYHTLRLALEFRALEPQGLLLYN-GNARGK----- 1418
CE V FE SF++ P A T ++ +FR EP GL+L++ G R +
Sbjct: 513 CENVATLDPITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKH 572
Query: 1419 ------DFLALALLDGRVQLRFDTGSGPAVLTSAVP-VEPGQWHRLELSRHWRRGTLSVD 1471
DF A+ +LDG + L D GSG + + + V G+W+ ++ R R GT+SV+
Sbjct: 573 PQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALLKKVNDGEWYHVDFQRDGRSGTISVN 632
Query: 1472 G-ETPVLGESPSGTDGLNLDTDLFVGGVPEDQAAVALER----TFVGAGLRGCIRLLDVN 1526
TP +P ++ L+LD +L++GG+PE++A + + G GCIR L ++
Sbjct: 633 TLRTPYT--APGESEILDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFID 690
Query: 1527 NQRLELG-IGPGAATRGSGVGECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTC 1585
Q ++ + +T G V P+C
Sbjct: 691 GQSKDIRQMAEVQSTAG--------------------------------------VKPSC 712
Query: 1586 ADEKS-PCQPNPCHGAAPCRVLPEGGAQ--CECP----LGREGTFCQTASGQDGSGPFLA 1638
+ E + PC NPC CR +G + C+C LGR T DGS
Sbjct: 713 SKETAKPCLSNPCKNNGMCR---DGWNRYVCDCSGTGYLGRSCEREATVLSYDGS----- 764
Query: 1639 DFNGFSHLELR-GLHTFARDLGEKMALEVVFLARGPSGLLLYNGQKTDGKGDFVSLALRD 1697
F ++L +HT A D+ + F ++ G+L+ + D + L L
Sbjct: 765 ---MFMKIQLPVVMHTEAEDVSLR------FRSQRAYGILMATTSR--DSADTLRLELDA 813
Query: 1698 RRLEFRYDL---------GKGAAVIRSREPVTLGAWTRVSLERNGRKGALRVGDGPRVLG 1748
R++ +L KG + + + W V + R G+ L V D + G
Sbjct: 814 GRVKLTVNLDCIRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTG 873
Query: 1749 ESPVPHTVLNLKEPLYVGGAPDFSKLARAAAVSSGFDGAIQLVSLGGRQLLTPEHVLRQV 1808
+ HT L + G + L ++V S F G +Q ++ G
Sbjct: 874 QMAGDHTRLEFHN-IETGIITERRYL---SSVPSNFIGHLQSLTFNG------------- 916
Query: 1809 DVTSFAGHPCTRASGHPCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVEKSAGDVDTLA 1868
AY+ LC G +CE + G + +A
Sbjct: 917 ----------------------------MAYIDLCKNG-DIDYCE---LNARFGFRNIIA 944
Query: 1869 FDGRTFVEYLNAVT-ESEKALQSNHFELSLRTEATQGLVLWSGKATERADYVALAIVDGH 1927
D TF + V + +A S H +T + GL+L++ + + D++ + +V G+
Sbjct: 945 -DPVTFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLILYN--SGDGNDFIVVELVKGY 1001
Query: 1928 LQLSYNLGSQPVVLR--STVPVNTNRWLRVVAHREQREGSLQVGNEAPVTGSSPLGATQL 1985
L ++LG+ +++ S P+N N+W V+ R+ V + +T GA L
Sbjct: 1002 LHYVFDLGNGANLIKGSSNKPLNDNQWHNVMISRD-TSNLHTVKIDTKITTQITAGARNL 1060
Query: 1986 DTDGALWLGGLPELPVGPALPKAYGT--GFVGCLRDVVVGRHPLHLLEDAV 2034
D L++GG+ + +LPK GF GCL V + L+ DA+
Sbjct: 1061 DLKSDLYIGGVAK-ETYKSLPKLVHAKEGFQGCLASVDLNGRLPDLISDAL 1110
Score = 84.0 bits (206), Expect = 1e-15
Identities = 84/385 (21%), Positives = 154/385 (40%), Gaps = 63/385 (16%)
Query: 1369 VLGAPVPAFEGRSFLAFPTLRAYHTLRLALEFRALEPQGLLLYNGNARGKDFLALALLDG 1428
++ PV S++A TL+AY ++ L +F+ GL+LYN + G DF+ + L+ G
Sbjct: 942 IIADPVTFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLILYN-SGDGNDFIVVELVKG 1000
Query: 1429 RVQLRFDTGSGPAVL--TSAVPVEPGQWHRLELSRHWRR-GTLSVDGETPVLGESPSGTD 1485
+ FD G+G ++ +S P+ QWH + +SR T+ +D T + + +G
Sbjct: 1001 YLHYVFDLGNGANLIKGSSNKPLNDNQWHNVMISRDTSNLHTVKID--TKITTQITAGAR 1058
Query: 1486 GLNLDTDLFVGGVPEDQAAVALERTFVGAGLRGCIRLLDVNNQRLELGIGPGAATRGSGV 1545
L+L +DL++GGV ++ + G +GC+ +D+N +
Sbjct: 1059 NLDLKSDLYIGGVAKETYKSLPKLVHAKEGFQGCLASVDLNGR----------------- 1101
Query: 1546 GECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRV 1605
LP+ C G++ C + CQ + C C +
Sbjct: 1102 --------LPDLISDALFCN-------------GQIERGCEGPSTTCQEDSCSNQGVC-L 1139
Query: 1606 LPEGGAQCECPL-GREGTFCQTASGQDGSGPFLADFNGFSHLELRGLHTFARDLGEKMAL 1664
G C+C + G C D ++ G G T+ ++ +
Sbjct: 1140 QQWDGFSCDCSMTSFSGPLC-----NDPGTTYIFSKGG-------GQITYKWPPNDRPST 1187
Query: 1665 EVVFLARGPSGL----LLYNGQKTDGKGDFVSLALRDRRLEFRYDLG-KGAAVIRSREPV 1719
LA G S + +L + G GD++ L + ++ ++++G A+ S +
Sbjct: 1188 RADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDIAIEESNAII 1247
Query: 1720 TLGAWTRVSLERNGRKGALRVGDGP 1744
G + V R+G L+V P
Sbjct: 1248 NDGKYHVVRFTRSGGNATLQVDSWP 1272
Score = 64.7 bits (156), Expect = 9e-10
Identities = 75/331 (22%), Positives = 126/331 (38%), Gaps = 28/331 (8%)
Query: 1662 MALEVVFLARGPSGLLLYNGQKTDGKGDFVSLALRDRRLEFRYDLGKGAAVIR--SREPV 1719
M L F GL+LYN DG DF+ + L L + +DLG GA +I+ S +P+
Sbjct: 967 MHLFFQFKTTSLDGLILYNSG--DGN-DFIVVELVKGYLHYVFDLGNGANLIKGSSNKPL 1023
Query: 1720 TLGAWTRVSLERNGRKGALRVGDGPRVLGESPVPHTVLNLKEPLYVGGA--PDFSKLARA 1777
W V + R+ V ++ + L+LK LY+GG + L +
Sbjct: 1024 NDNQWHNVMISRD-TSNLHTVKIDTKITTQITAGARNLDLKSDLYIGGVAKETYKSLPKL 1082
Query: 1778 AAVSSGFDGAIQLVSLGGR-QLLTPEHVLRQVDVTSFAGHPCTRASGHPCLNGASCVPRE 1836
GF G + V L GR L + + + P T C N C+ +
Sbjct: 1083 VHAKEGFQGCLASVDLNGRLPDLISDALFCNGQIERGCEGPSTTCQEDSCSNQGVCLQQW 1142
Query: 1837 AAYVCLCP-GGFSGPHCEKG----LVEKSAGDVDTLAFDGRTFVEYLNAVTESEKALQSN 1891
+ C C FSGP C + K G + + +++
Sbjct: 1143 DGFSCDCSMTSFSGPLCNDPGTTYIFSKGGGQIT------------YKWPPNDRPSTRAD 1190
Query: 1892 HFELSLRTEATQGLVLWSGKATERADYVALAIVDGHLQLSYNLGSQPVVL-RSTVPVNTN 1950
+ T + +++ ++ DY+ L I G + + +N+G+ + + S +N
Sbjct: 1191 RLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDIAIEESNAIINDG 1250
Query: 1951 RWLRVVAHREQREGSLQVGNEAPVTGSSPLG 1981
++ V R +LQV + PV P G
Sbjct: 1251 KYHVVRFTRSGGNATLQV-DSWPVIERYPAG 1280
Score = 63.5 bits (153), Expect = 2e-09
Identities = 52/207 (25%), Positives = 89/207 (42%), Gaps = 19/207 (9%)
Query: 1320 GRRPPAPQQPPKPCDSQPCFHGGTCQD-WALGGGFTCSCP-AGRGGAVCEKVLGAPVPAF 1377
G +P ++ KPC S PC + G C+D W + C C G G CE+ A V ++
Sbjct: 707 GVKPSCSKETAKPCLSNPCKNNGMCRDGW---NRYVCDCSGTGYLGRSCER--EATVLSY 761
Query: 1378 EGRSFLAFPTLRAYHTLR--LALEFRALEPQGLLLYNGNARGKDFLALALLDGRVQL--- 1432
+G F+ HT ++L FR+ G+L+ + D L L L GRV+L
Sbjct: 762 DGSMFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVKLTVN 821
Query: 1433 ------RFDTGSGPAVLTSAVPVEPGQWHRLELSRHWRRGTLSVDGETPVLGESPSGTDG 1486
++ GP L + + +WH + + R + L+VD + + G+
Sbjct: 822 LDCIRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGDHTR 881
Query: 1487 LNLDTDLFVGGVPEDQAAVALERTFVG 1513
L ++ G + E + ++ F+G
Sbjct: 882 LEFH-NIETGIITERRYLSSVPSNFIG 907
>gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens]
Length = 4588
Score = 133 bits (335), Expect = 2e-30
Identities = 92/316 (29%), Positives = 130/316 (41%), Gaps = 22/316 (6%)
Query: 1320 GRRPPAPQQPPKPCDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEKVLGAPVPAFEG 1379
GR PP C+ PC G C TC CP+GR G + G+ G
Sbjct: 3785 GRCPPVHHG----CEDDPCPEGSECVSDPWEEKHTCVCPSGRFG----QCPGSSSMTLTG 3836
Query: 1380 RSFLAFPTLRAYHTL--RLALEFRALEPQGLLLYNGNARGKDFLALALLDGRVQLRFDTG 1437
S++ + + L +L + R +++Y ARG D+ L + GR+Q +FD G
Sbjct: 3837 NSYVKYRLTENENKLEMKLTMRLRTYSTHAVVMY---ARGTDYSILEIHHGRLQYKFDCG 3893
Query: 1438 SGPAVLT-SAVPVEPGQWHRLELSRHWRRGTLSVDGETPVLGESPSGTDGLNLDTDLFVG 1496
SGP +++ ++ V GQWH + L + L +D G +P LNLD +F G
Sbjct: 3894 SGPGIVSVQSIQVNDGQWHAVALEVNGNYARLVLDQVHTASGTAPGTLKTLNLDNYVFFG 3953
Query: 1497 GVPEDQAAVALERTFVGAGLRGCIRLLDVNNQRLELGIGPGAATR-------GSGVGECG 1549
G Q VG G RGC+ + +N Q L L P + G
Sbjct: 3954 GHIRQQGTRHGRSPQVGNGFRGCMDSIYLNGQELPLNSKPRSYAHIEESVDVSPGCFLTA 4013
Query: 1550 DHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEG 1609
C NPC G C AG ++C+C +G C +PC PC C V+ G
Sbjct: 4014 TEDCASNPCQNGGVCNPSPAGGYYCKCSALYIGTHCEISVNPCSSKPCLYGGTC-VVDNG 4072
Query: 1610 GAQCECPLGREGTFCQ 1625
G C+C G CQ
Sbjct: 4073 GFVCQCRGLYTGQRCQ 4088
Score = 80.1 bits (196), Expect = 2e-14
Identities = 78/295 (26%), Positives = 115/295 (38%), Gaps = 39/295 (13%)
Query: 1574 CQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLP-EGGAQCECPLGREGTFCQTASGQDG 1632
C C GR C C+ +PC + C P E C CP GR G C +S
Sbjct: 3780 CLCKEGR----CPPVHHGCEDDPCPEGSECVSDPWEEKHTCVCPSGRFGQ-CPGSSSMTL 3834
Query: 1633 SGPFLADFN---GFSHLELRGLHTFARDLGEKMALEVVFLARGPSGLLLYNGQKTDGKGD 1689
+G + + LE++ L VV ARG D
Sbjct: 3835 TGNSYVKYRLTENENKLEMK----LTMRLRTYSTHAVVMYARGT---------------D 3875
Query: 1690 FVSLALRDRRLEFRYDLGKGAAVIRSRE-PVTLGAWTRVSLERNGRKGALRVGDGPRVLG 1748
+ L + RL++++D G G ++ + V G W V+LE NG L + G
Sbjct: 3876 YSILEIHHGRLQYKFDCGSGPGIVSVQSIQVNDGQWHAVALEVNGNYARLVLDQVHTASG 3935
Query: 1749 ESPVPHTVLNLKEPLYVGG--APDFSKLARAAAVSSGFDGAIQLVSLGGRQL------LT 1800
+P LNL ++ GG ++ R+ V +GF G + + L G++L +
Sbjct: 3936 TAPGTLKTLNLDNYVFFGGHIRQQGTRHGRSPQVGNGFRGCMDSIYLNGQELPLNSKPRS 3995
Query: 1801 PEHVLRQVDVTSFAGHPCTR-ASGHPCLNGASCVPREA-AYVCLCPGGFSGPHCE 1853
H+ VDV+ T + +PC NG C P A Y C C + G HCE
Sbjct: 3996 YAHIEESVDVSPGCFLTATEDCASNPCQNGGVCNPSPAGGYYCKCSALYIGTHCE 4050
Score = 47.8 bits (112), Expect = 1e-04
Identities = 33/110 (30%), Positives = 42/110 (38%), Gaps = 14/110 (12%)
Query: 461 CDQAPSPCLGVQCAFGATCAVKNGQAACECL-----QACSSLYDPVCGSDGVTYGSAC-- 513
C+ + +PC C +G TC V NG C+C Q C P C + G C
Sbjct: 4049 CEISVNPCSSKPCLYGGTCVVDNGGFVCQCRGLYTGQRCQ--LSPYCKDEPCKNGGTCFD 4106
Query: 514 ELEATACTLGREIQVAR-KGPCDRC--GQCRFGALCEAETG--RCVCPSE 558
L+ C + R + D C C GALCE G C C E
Sbjct: 4107 SLDGAVCQCDSGFRGERCQSDIDECSGNPCLHGALCENTHGSYHCNCSHE 4156
Score = 43.1 bits (100), Expect = 0.003
Identities = 24/76 (31%), Positives = 28/76 (36%), Gaps = 2/76 (2%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQ 1612
C PC G C + G CQC G G C + C NPC A C G
Sbjct: 4093 CKDEPCKNGGTCFDSLDGAV-CQCDSGFRGERCQSDIDECSGNPCLHGALCE-NTHGSYH 4150
Query: 1613 CECPLGREGTFCQTAS 1628
C C G C+ A+
Sbjct: 4151 CNCSHEYRGRHCEDAA 4166
Score = 40.8 bits (94), Expect = 0.014
Identities = 43/150 (28%), Positives = 53/150 (35%), Gaps = 16/150 (10%)
Query: 131 ELMLNSSLMRITLRNLEEVEFCVEDKPGTHFTPVPPTPPDACRGMLCGFGAVCEPNAEGP 190
EL LNS R+ +E V+ PG T + C C G VC P+ G
Sbjct: 3986 ELPLNSKP-----RSYAHIEESVDVSPGCFLTAT-----EDCASNPCQNGGVCNPSPAGG 4035
Query: 191 GRASCVCKK--SPCPSVVAPVCGSDASTYSNECELQRAQCSQQRRIRLLSRGPCGSRDPC 248
C + C V P C S Y C + Q R L + C C
Sbjct: 4036 YYCKCSALYIGTHCEISVNP-CSSKPCLYGGTCVVDNGGFVCQCR-GLYTGQRCQLSPYC 4093
Query: 249 SNVTCSFGSTCARSADGLTASCLCPATCRG 278
+ C G TC S DG A C C + RG
Sbjct: 4094 KDEPCKNGGTCFDSLDG--AVCQCDSGFRG 4121
Score = 40.4 bits (93), Expect = 0.018
Identities = 41/160 (25%), Positives = 55/160 (34%), Gaps = 31/160 (19%)
Query: 778 ITAARGVGLAGCPSACQCNPH--GSY---------GGTCDPATGQCSCRPGVGGLRCDRC 826
+TA C + CNP G Y G C+ + CS +P + G C
Sbjct: 4011 LTATEDCASNPCQNGGVCNPSPAGGYYCKCSALYIGTHCEISVNPCSSKPCLYGGTCVVD 4070
Query: 827 EPGF-WNFRGIVTDGRSGCTP-CSCDPQGAVRDDCEQMTG-LCSCKPGVAGPKCGQCPDG 883
GF RG+ T R +P C +P + + G +C C G G +C D
Sbjct: 4071 NGGFVCQCRGLYTGQRCQLSPYCKDEPCKNGGTCFDSLDGAVCQCDSGFRGERCQSDID- 4129
Query: 884 RALGPAGCEADASAPATCAEMRCEFGARCVEESGSAHCVC 923
C+ C GA C GS HC C
Sbjct: 4130 ----------------ECSGNPCLHGALCENTHGSYHCNC 4153
Score = 39.3 bits (90), Expect = 0.040
Identities = 18/47 (38%), Positives = 23/47 (48%), Gaps = 4/47 (8%)
Query: 1811 TSFAGHPCT----RASGHPCLNGASCVPREAAYVCLCPGGFSGPHCE 1853
+ F G C SG+PCL+GA C +Y C C + G HCE
Sbjct: 4117 SGFRGERCQSDIDECSGNPCLHGALCENTHGSYHCNCSHEYRGRHCE 4163
Score = 38.5 bits (88), Expect = 0.068
Identities = 38/141 (26%), Positives = 50/141 (35%), Gaps = 24/141 (17%)
Query: 696 EDSEDGPCVCDFSCQSVP-GSPVCGSDGVTYSTECELKKARCESQRGLY----VAAQGA- 749
ED PC C P G C + T CE+ C S+ LY V G
Sbjct: 4015 EDCASNPCQNGGVCNPSPAGGYYCKCSALYIGTHCEISVNPCSSKPCLYGGTCVVDNGGF 4074
Query: 750 ---CRGPTFAPLPPVAPLHCAQTPY---GCCQDNITAARGVGLAGCPSACQCNPHGSYGG 803
CRG ++P +C P G C D++ A CQC+ G G
Sbjct: 4075 VCQCRGLYTGQRCQLSP-YCKDEPCKNGGTCFDSLDGA----------VCQCD-SGFRGE 4122
Query: 804 TCDPATGQCSCRPGVGGLRCD 824
C +CS P + G C+
Sbjct: 4123 RCQSDIDECSGNPCLHGALCE 4143
Score = 33.9 bits (76), Expect = 1.7
Identities = 14/36 (38%), Positives = 17/36 (47%)
Query: 1825 PCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVEKS 1860
PC NG +C VC C GF G C+ + E S
Sbjct: 4097 PCKNGGTCFDSLDGAVCQCDSGFRGERCQSDIDECS 4132
Score = 32.0 bits (71), Expect = 6.4
Identities = 14/35 (40%), Positives = 18/35 (51%), Gaps = 2/35 (5%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCE 1367
C +PC +GGTC D G C C +G G C+
Sbjct: 4093 CKDEPCKNGGTCFDSL--DGAVCQCDSGFRGERCQ 4125
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 127 bits (319), Expect = 1e-28
Identities = 226/874 (25%), Positives = 277/874 (31%), Gaps = 214/874 (24%)
Query: 193 ASCVCKKSPCPSVVAPVCGSDASTYSNECELQRAQCSQQRRIRLLSRGPCGSRDPCSNVT 252
+SC C +PC V C +CE A C + R G ++ C
Sbjct: 742 SSCSCGGAPCHGVTGQ-CRCPPGRTGEDCE---ADCPE-------GRWGLGCQEICP--A 788
Query: 253 CSFGSTCARSADGLTASCLCPATCRGAPEGTVCGSDGADYPGECQLLRRACARQENVFKK 312
C + C D T +CLC G+ VC + Y CQ R +CA
Sbjct: 789 CQHAARC----DPETGACLCLPGFVGSRCQDVCPAGW--YGPSCQT-RCSCAN------- 834
Query: 313 FDGPCDP---------------CQGAL------PDPSRSCRVNPRTRRPEMLLRPESCPA 351
DG C P CQ A PD S C + + + C A
Sbjct: 835 -DGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEA 893
Query: 352 RQAPVCGDDGVTYENDCVMGRSGAARGLLLQKVRSGQCQ---GRDQCP---------EPC 399
G G E C G G Q C G CP C
Sbjct: 894 ------GYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHAC 947
Query: 400 RFNAVCLSRRGRPRCS----CDRVT----CDGAYR-PVCAQD--GRTYDSDCWRQQAECR 448
L R C+ CD V C R P CA+ TY +C Q C
Sbjct: 948 PAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNC-SQACACF 1006
Query: 449 QQRAIPSKHQGPCDQAPSPCLGVQCAFGATCAVKNGQAACECLQACSSLYDPV---CGSD 505
+ H G C AP +G C + CL DPV C
Sbjct: 1007 NGASCDPVH-GQCHCAPG-WMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACP 1064
Query: 506 GVTYGSACELEATACTLGREIQVARKGPCDRCGQCRFGALCEAETGRCVCPSECVA-LAQ 564
G ACE E L R+++ C G C G LC+ TGRC+CP+ Q
Sbjct: 1065 EGWAGLACEKEC----LPRDVRAG----CRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQ 1116
Query: 565 PVC--GSDGHTYPSECMLHVHACTHQISLHVASAGPCET------CGDAVCAFGAVCSAG 616
C G G C A H HV A C C A C G S G
Sbjct: 1117 SPCLRGWFGEACAQRCSCPPGAACH----HVTGACRCPPGFTGSGCEQA-CPPG---SFG 1168
Query: 617 QCVCPRCEHPPPGPVCGSDGVTYGSACELREAACLQQTQIEEARAGP-CEQ-AECGSGGS 674
+ C+ P P C T A +C Q + R GP CEQ C +GGS
Sbjct: 1169 EDCAQMCQCPGENPACHPATGTCSCAAGYHGPSC--QQRCPPGRYGPGCEQLCGCLNGGS 1226
Query: 675 GSGEDGDCEQELCRQRGGIWDEDSEDGPCVCDFSCQSVPGSP----VCGS------DGVT 724
G CR G D C+ +C P VCG D VT
Sbjct: 1227 CDAATG-----ACRCPTGFLGTD-------CNLTCPQGRFGPNCTHVCGCGQGAACDPVT 1274
Query: 725 YSTECELKKARCESQRGLYVAAQGACRGPTFAPLPPVAPLHCAQTPYG--CCQDNITAAR 782
+ C +A +RG C F V H G C N + +
Sbjct: 1275 GTCLCPPGRAGVRCERG--------CPQNRFG----VGCEHTCSCRNGGLCHASNGSCSC 1322
Query: 783 GVGLAG--CPSACQCNPHGSYGG------------TCDPATGQCSCRPGVGGLRCDR-CE 827
G+G G C AC P G YG TC+PATG C C PG G C+ C
Sbjct: 1323 GLGWTGRHCELAC---PPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCP 1379
Query: 828 PGF---------WNFRGIVTD---GR-------------SGCTPCS--------CDPQGA 854
PGF W G D GR GC P S CD G
Sbjct: 1380 PGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGG 1439
Query: 855 VRDDCEQMTGLCSCKPGVAGPKCGQCPDGRALGPAGCEADASAPATCAEMRCEFGARCVE 914
C+ +TGLC C PG +G C C P+ C GA C
Sbjct: 1440 A--PCDPVTGLCLCPPGRSGATCN----------LDCRRGQFGPSCTLHCDCGGGADCDP 1487
Query: 915 ESGSAHCVCPML--TCPEANATKVCGSDGVTYGN 946
SG HCV + TC E ++ + + G+
Sbjct: 1488 VSGQCHCVDGYMGPTCREGGPLRLPENPSLAQGS 1521
Score = 111 bits (277), Expect = 8e-24
Identities = 183/785 (23%), Positives = 254/785 (32%), Gaps = 167/785 (21%)
Query: 210 CGSDASTYSNECELQR--AQCSQQRRIRLLSRGP-CGSRDPCSNVTCSFGSTCARSADGL 266
C + + + C++ R A+C +L + G C D C+ C +
Sbjct: 248 CANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGSF 307
Query: 267 TASCLCPATCRGAPEGTVCGSDGADYPGECQLLRRACARQENVFKKFDGPCDPCQGA--L 324
C+C A +G C + C+ C+ GP C L
Sbjct: 308 --KCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSH--GCSHTSAGPLCTCPRGYEL 363
Query: 325 PDPSRSCRVNPRTRRPEMLLRPESC---PARQAPVCGDDGVTYENDCVMGRSGAARGLLL 381
R+C + + C P Q VC ++ YE C G +A G
Sbjct: 364 DTDQRTC------------IDVDDCADSPCCQQ-VCTNNPGGYECGCYAGYRLSADGC-- 408
Query: 382 QKVRSGQCQGRDQCPEP---CRFNAVCLSRRGRPRCSC--------DRVTCDGAYRPVCA 430
C+ D+C C + C + G +CSC DR C P+
Sbjct: 409 ------GCEDVDECASSRGGCEHH--CTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVD 460
Query: 431 QDGRT--------------------YDSDCW--RQQAECRQQRAIPSKHQGPCDQAPSPC 468
DG D D ++AE R + + K D C
Sbjct: 461 LDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDC 520
Query: 469 LGV--QCAFGATCAVKNGQAACECLQACSSLY-DPVCGSDGVTYGSACELEATACTLGRE 525
C G TC + G C+C + + L + C D T+G C +
Sbjct: 521 SLTCDDCRNGGTCLL--GLDGCDCPEGWTGLICNETCPPD--TFGKNCSFSCS------- 569
Query: 526 IQVARKGPCDRCGQCRFGALCEAETGRCVCPSECVALAQPVCGSDGHTYPSECMLHVHAC 585
C+ G C++ TG C CP G G C +
Sbjct: 570 --------------CQNGGTCDSVTGACRCPP----------GVSGTNCEDGCPKGYYGK 605
Query: 586 THQISLHVASAGPCETC-GDAVCAFGAVCSAGQCVCPRCEHPPPGPVCGSD---GVTYGS 641
+ + A+ G C G +C G CP GP C + +
Sbjct: 606 HCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAF---GPGCSEECQCVQPHTQ 662
Query: 642 ACELREAACLQQTQIEEARAGPCEQAECGSGGSGSGEDGDCEQELCRQRGGIWDEDSEDG 701
+C+ R+ +C + R QAEC G G G C Q G D S +
Sbjct: 663 SCDKRDGSCSCKAGFRGERC----QAECELGYFGPG----CWQACTCPVGVACDSVSGEC 714
Query: 702 PCVCDFSCQSVPGSPVC--GSDGVTYSTECELKKARCESQRGLYVAAQGACRGPTFAPLP 759
C Q C G+ GV S+ C A C G G A P
Sbjct: 715 GKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCP 774
Query: 760 PVA-PLHCAQTPYGC-----CQDNITAARGV-GLAG------CPS-----ACQCNPHGSY 801
L C + C C A + G G CP+ +CQ +
Sbjct: 775 EGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCAN 834
Query: 802 GGTCDPATGQCSCRPGVGGLRCDR-CEPGFWNFRGIVTDGRSGCTPCSCDPQGAVRDDCE 860
G C PATG CSC PG G C R C+ G W G PC+C A C+
Sbjct: 835 DGHCHPATGHCSCAPGWTGFSCQRACDTGHW--------GPDCSHPCNC---SAGHGSCD 883
Query: 861 QMTGLCSCKPGVAGPKC-GQCPDGRALGPAGCEADASAPATCAEMRCEFGARCVEESGSA 919
++GLC C+ G GP+C QCP G GP GCE +C+ GA C SG+
Sbjct: 884 AISGLCLCEAGYVGPRCEQQCPQGH-FGP-GCE---------QRCQCQHGAACDHVSGA- 931
Query: 920 HCVCP 924
C CP
Sbjct: 932 -CTCP 935
Score = 110 bits (276), Expect = 1e-23
Identities = 251/1003 (25%), Positives = 307/1003 (30%), Gaps = 259/1003 (25%)
Query: 183 CEPNAEGPGRAS-CVCKKSPCPSVVAPVCGSDASTYSNECELQRAQCSQQRRIRLLSRGP 241
C P A GPG + C C + S C + S + + +C Q L GP
Sbjct: 641 CPPWAFGPGCSEECQCVQPHTQS-----CDKRDGSCSCKAGFRGERC--QAECELGYFGP 693
Query: 242 CGSRDPCSNVTCSFGSTCARSADGLTASC--LCPATCRGAPEGTVC--GSDGADYPGECQ 297
G C TC G C D ++ C CPA +G G C G+ G + C
Sbjct: 694 -GCWQAC---TCPVGVAC----DSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSC- 744
Query: 298 LLRRACARQENVFKKFDGPCDPCQGALPDPSRSCRVNPRTRRPEMLLRPESCPARQAPVC 357
+C PC G + CR P
Sbjct: 745 ----SCGGA------------PCHGV----TGQCRCPP---------------------- 762
Query: 358 GDDGVTYENDCVMGRSGAARGLLLQKVRSGQCQGRDQC-PEPCRFNAVCLSRRGRPRCSC 416
G G E DC GR G L Q++ CQ +C PE CL G C
Sbjct: 763 GRTGEDCEADCPEGRWG----LGCQEICPA-CQHAARCDPE----TGACLCLPGFVGSRC 813
Query: 417 DRVTCDGAYRPVC------AQDGRTYDS----DCWRQQAECRQQRAIPSKHQGPCDQAPS 466
V G Y P C A DG + + C QRA + H GP P
Sbjct: 814 QDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPC 873
Query: 467 PCL---GVQCAFGATCAVKNGQAACECLQAC-SSLYDPVCGSD-GVTYGSACELEATACT 521
C G A C + G C Q C + P C +G+AC+ + ACT
Sbjct: 874 NCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACT 933
Query: 522 L-----GREIQVARKG-----PCDRCGQCRFGALCEAETGRCVCPSECVALAQPVCGSD- 570
G + A C C GA C+A G C+CP+ P C
Sbjct: 934 CPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPA---GRRGPRCAETC 990
Query: 571 -GHTYPSECMLHVHACTHQISLHVASAGPCETCGDAVCAFGAVCSAGQCVCP------RC 623
HTY C AC + AS P G CA G + + CP C
Sbjct: 991 PAHTYGHNCS---QACA---CFNGASCDPVH--GQCHCAPGWMGPSCLQACPAGLYGDNC 1042
Query: 624 EHP---PPGPVCGSDGVTYGSACELREA--ACLQQTQIEEARAGPCEQAECGSGGSGSGE 678
H G C D V+ AC A AC ++ + RAG C +GG
Sbjct: 1043 RHSCLCQNGGTC--DPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPH 1100
Query: 679 DGDCEQELCRQRGGIWDEDSEDGPCV-------CDFSCQSVPGSPVCGSDGVTYSTECE- 730
G C LC W D PC+ C C PG+ VT + C
Sbjct: 1101 TGRC---LCPAG---WTGDKCQSPCLRGWFGEACAQRCSCPPGA---ACHHVTGACRCPP 1151
Query: 731 -LKKARCES-----QRGLYVAAQGACRGPTFAPLPPVAPLHCAQTPYG-CCQDNITAAR- 782
+ CE G A C G A P CA +G CQ R
Sbjct: 1152 GFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRY 1211
Query: 783 GVG---LAGC---------PSACQCN------------PHGSYG------------GTCD 806
G G L GC AC+C P G +G CD
Sbjct: 1212 GPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACD 1271
Query: 807 PATGQCSCRPGVGGLRCDR----------CEPGFWNFRGIVTDGRSGCTPC--------- 847
P TG C C PG G+RC+R CE G + +G C
Sbjct: 1272 PVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHC 1331
Query: 848 --SCDP--QGAV---------RDDCEQMTGLCSCKPGVAGPKCGQ-CPDG-RALGPAG-C 891
+C P GA CE TG C C PG G C CP G G G C
Sbjct: 1332 ELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLC 1391
Query: 892 EADASAPATCAEMRC------------------EFGARCVEE---SGSAHC--VCPMLTC 928
AP RC FG C + G A C V + C
Sbjct: 1392 WCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGLCLC 1451
Query: 929 PEANATKVCGSDGVTYGNECQLKTIACRQGLQISIQSLGPCQEAVAPSTHPTSASVTVTT 988
P + C D CR+G Q C P S
Sbjct: 1452 PPGRSGATCNLD--------------CRRG-QFGPSCTLHCDCGGGADCDPVSGQCH-CV 1495
Query: 989 PGLLLSQALPAPPGALPLAPSSTAHSQTTPPPSSRPRTTASVP 1031
G + P LP PS S T P SSRP + + P
Sbjct: 1496 DGYMGPTCREGGPLRLPENPSLAQGSAGTLPASSRPTSRSGGP 1538
Score = 74.3 bits (181), Expect = 1e-12
Identities = 161/693 (23%), Positives = 219/693 (31%), Gaps = 186/693 (26%)
Query: 377 RGLLLQKVRSGQCQGRDQCPEPCRFNAVCLSRRGRPRCSCDRVTCDGAYRPVCAQDG--- 433
RG + Q G C + C C+ +P C C G P C D
Sbjct: 112 RGWMQQPDEEG-CLSAECSASLCFHGGRCVPGSAQP-CHCP----PGFQGPRCQYDVDEC 165
Query: 434 RTYDSDCWRQQAECRQQRAIPSKHQGPCDQAPSPCLGVQ---CAFGATCAVKNGQAACEC 490
RT++ C Q R + + C+ P L C +CA+ NG C
Sbjct: 166 RTHNGGC--------QHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHC 217
Query: 491 LQACSSLYDPVCGSDGVTYGSACELEATACTLGREIQVARKGPC-DRCGQCRFGALCEAE 549
+Q + + C G + + C + R R G C RC R A CE
Sbjct: 218 VQLTITRHRCQCRP-----GFQLQEDGRHC-VRRSPCANRNGSCMHRCQVVRGLARCECH 271
Query: 550 TG--------RCVCPSECVA-LAQPVCGSDGHTYPSECMLHV--------HACTHQISLH 592
G C EC A LAQ G +C+ H C ++I +
Sbjct: 272 VGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQC-YRIEME 330
Query: 593 VASAGPCETCGDAVCAFGAV-CSAGQ-CVCPRCEHPPPGPVCGSDGVTYGSACELREAAC 650
+ ++ CE + C+ G SAG C CPR G +D T + ++ C
Sbjct: 331 IVNS--CEA-NNGGCSHGCSHTSAGPLCTCPR------GYELDTDQRTCIDVDDCADSPC 381
Query: 651 LQQTQIEEARAGPCEQAECGSGGSGSGEDGDCEQ--ELCRQRGGIWDEDSEDGPCVCDFS 708
QQ C C +G S + CE E RGG C+
Sbjct: 382 CQQVCTNNPGGYECG---CYAGYRLSADGCGCEDVDECASSRGG------------CEHH 426
Query: 709 CQSVPGSPVCGSDGVTYSTECELKKARCESQRGL------YVAAQGACRGPTFAPLPPVA 762
C ++ GS C CE E +RG V G P PLP +A
Sbjct: 427 CTNLAGSFQCS---------CEAGYRLHEDRRGCSPLEEPMVDLDGEL--PFVRPLPHIA 475
Query: 763 PLH--------------------------------CAQTPYG------C--CQDNITAAR 782
L C +G C C++ T
Sbjct: 476 VLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGGTCLL 535
Query: 783 GVGLAGCPSA------------------CQCNPHGSYGGTCDPATGQCSCRPGVGGLRC- 823
G+ CP C + GGTCD TG C C PGV G C
Sbjct: 536 GLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSGTNCE 595
Query: 824 DRCEPGFWNFRGIVTDGRSGCTPCSCDPQGAVRDDCEQMTGLCSCKPGVAGPKCGQCPDG 883
D C G++ G+ C+C A R C ++ G C C PG+ G C
Sbjct: 596 DGCPKGYY--------GKHCRKKCNC----ANRGRCHRLYGACLCDPGLYGRFCHLTCPP 643
Query: 884 RALGPAGCEADASA-----------PATCAEMRCEFGARCVEESGSAH--------CVCP 924
A GP GC + +C+ G RC E + C CP
Sbjct: 644 WAFGP-GCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCP 702
Query: 925 M-LTCPEANAT--KVC--GSDGVTYGNECQLKT 952
+ + C + K C G G G EC + T
Sbjct: 703 VGVACDSVSGECGKRCPAGFQGEDCGQECPVGT 735
Score = 45.4 bits (106), Expect = 6e-04
Identities = 32/85 (37%), Positives = 38/85 (44%), Gaps = 17/85 (20%)
Query: 1551 HPCLPNPCHGGAPCQN----LEAG----RFHCQCPPGRVGPTCADEKSPCQPNPCHGAAP 1602
HPC + HG + EAG R QCP G GP C +++ CQ HGAA
Sbjct: 871 HPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGC-EQRCQCQ----HGAAC 925
Query: 1603 CRVLPEGGAQCECPLGREGTFCQTA 1627
V C CP G GTFC+ A
Sbjct: 926 DHV----SGACTCPAGWRGTFCEHA 946
Score = 45.4 bits (106), Expect = 6e-04
Identities = 35/111 (31%), Positives = 44/111 (39%), Gaps = 31/111 (27%)
Query: 1546 GECGDHPCLPNP----------CHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPN 1595
G+ +HPC P C GAPC + +GR C CP G G C + C+P
Sbjct: 1371 GQACEHPCPPGFHGAGCQGLCWCQHGAPCDPI-SGR--CLCPAGFHGHFC---ERGCEPG 1424
Query: 1596 P----CHGAAPCRVLPEGGAQCE-------CPLGREGTFCQTASGQDGSGP 1635
CH C +GGA C+ CP GR G C + GP
Sbjct: 1425 SFGEGCHQRCDC----DGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGP 1471
Score = 42.7 bits (99), Expect = 0.004
Identities = 33/92 (35%), Positives = 37/92 (40%), Gaps = 13/92 (14%)
Query: 1541 RGSGVGECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNP---- 1596
RG G G+ C GGAPC + C CPPGR G TC + Q P
Sbjct: 1419 RGCEPGSFGEGCHQRCDCDGGAPCDPVTG---LCLCPPGRSGATCNLDCRRGQFGPSCTL 1475
Query: 1597 ---CHGAAPCRVLPEGGAQCECPLGREGTFCQ 1625
C G A C P G QC C G G C+
Sbjct: 1476 HCDCGGGADCD--PVSG-QCHCVDGYMGPTCR 1504
Score = 41.2 bits (95), Expect = 0.010
Identities = 31/84 (36%), Positives = 35/84 (41%), Gaps = 14/84 (16%)
Query: 1560 GGAPCQNLEAGRFHCQCPPGRVGPTCADEKSP------CQP--NPCHGAAPCRVLPEGGA 1611
GGAPC + C+CPPGR G C + CQ C AA C PE GA
Sbjct: 747 GGAPCHGVTG---QCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCD--PETGA 801
Query: 1612 QCECPLGREGTFCQTASGQDGSGP 1635
C C G G+ CQ GP
Sbjct: 802 -CLCLPGFVGSRCQDVCPAGWYGP 824
Score = 40.0 bits (92), Expect = 0.023
Identities = 34/110 (30%), Positives = 41/110 (37%), Gaps = 29/110 (26%)
Query: 1539 ATRGS---GVGECGDHPCLPNP-------CHGGAPCQN---LEAGRFHCQCPPGRVGPTC 1585
A+ GS G+G G H L P CH C N E C+C PG G C
Sbjct: 1315 ASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQAC 1374
Query: 1586 ADEKSPCQPNP----------CHGAAPCRVLPEGGAQCECPLGREGTFCQ 1625
+ PC P C APC + +C CP G G FC+
Sbjct: 1375 ---EHPCPPGFHGAGCQGLCWCQHGAPCDPI---SGRCLCPAGFHGHFCE 1418
Score = 37.7 bits (86), Expect = 0.12
Identities = 29/92 (31%), Positives = 33/92 (35%), Gaps = 19/92 (20%)
Query: 1549 GDHPCLPNPCHGGAPCQNLEAGRFH---CQ--CPPGRVGPTCADEKSPCQPNPCHGAAPC 1603
G++P +P G C A +H CQ CPPGR GP C C A
Sbjct: 1179 GENPAC-HPATGTCSC----AAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAAT-- 1231
Query: 1604 RVLPEGGAQCECPLGREGTFCQTASGQDGSGP 1635
C CP G GT C Q GP
Sbjct: 1232 -------GACRCPTGFLGTDCNLTCPQGRFGP 1256
Score = 37.0 bits (84), Expect = 0.20
Identities = 29/80 (36%), Positives = 34/80 (42%), Gaps = 10/80 (12%)
Query: 1558 CH---GGAPCQNLEAGRF-HCQCPPGRVGPTCADEKSPCQPN--PC---HGAAPCRVLPE 1608
CH G C GRF H CPP GP C++E QP+ C G+ C+
Sbjct: 619 CHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFR 678
Query: 1609 G-GAQCECPLGREGTFCQTA 1627
G Q EC LG G C A
Sbjct: 679 GERCQAECELGYFGPGCWQA 698
Score = 37.0 bits (84), Expect = 0.20
Identities = 31/77 (40%), Positives = 33/77 (42%), Gaps = 10/77 (12%)
Query: 1558 CH---GGAPCQNLEAGRFHCQ--CPPGRVGPTCADEKSPCQPNPCHGA-APCRVLPE-GG 1610
CH G C GR HC+ CPPGR G C E S + C A CR P G
Sbjct: 1313 CHASNGSCSCGLGWTGR-HCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYG 1371
Query: 1611 AQCE--CPLGREGTFCQ 1625
CE CP G G CQ
Sbjct: 1372 QACEHPCPPGFHGAGCQ 1388
Score = 36.6 bits (83), Expect = 0.26
Identities = 45/160 (28%), Positives = 51/160 (31%), Gaps = 25/160 (15%)
Query: 1479 ESPSGTDGLNLDTDLFVGGVPEDQAAVALERTFVGAGLRGCIRLLDVNNQRLELG---IG 1535
E P GT G+N + GG P R G C D R LG I
Sbjct: 730 ECPVGTFGVNCSSSCSCGGAP-CHGVTGQCRCPPGRTGEDCEA--DCPEGRWGLGCQEIC 786
Query: 1536 PGAATRGSGVGECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPN 1595
P E G CLP G+ CQ++ CP G GP+C S
Sbjct: 787 PACQHAARCDPETGACLCLPG--FVGSRCQDV--------CPAGWYGPSCQTRCSCANDG 836
Query: 1596 PCHGAAPCRVLPEGGAQCECPLGREGTFCQTASGQDGSGP 1635
CH A C C G G CQ A GP
Sbjct: 837 HCHPAT---------GHCSCAPGWTGFSCQRACDTGHWGP 867
Score = 36.2 bits (82), Expect = 0.34
Identities = 27/86 (31%), Positives = 31/86 (36%), Gaps = 22/86 (25%)
Query: 1551 HPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNP----CHGAAPCRVL 1606
H CL C G C + HC CP G G C E C P C + C
Sbjct: 1044 HSCL---CQNGGTCDPVSG---HCACPEGWAGLACEKE---CLPRDVRAGCRHSGGCL-- 1092
Query: 1607 PEGG------AQCECPLGREGTFCQT 1626
GG +C CP G G CQ+
Sbjct: 1093 -NGGLCDPHTGRCLCPAGWTGDKCQS 1117
Score = 36.2 bits (82), Expect = 0.34
Identities = 17/38 (44%), Positives = 20/38 (52%), Gaps = 2/38 (5%)
Query: 1826 CLNGASCVPREAAYVCLCPGGFSGPHCEKGLVEKSAGD 1863
C +GA C P CLCP GF G CE+G S G+
Sbjct: 1393 CQHGAPCDPISGR--CLCPAGFHGHFCERGCEPGSFGE 1428
Score = 35.8 bits (81), Expect = 0.44
Identities = 29/90 (32%), Positives = 33/90 (36%), Gaps = 21/90 (23%)
Query: 1558 CHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSP----------CQ---PNP-CH---GA 1600
C GA C ++ C+CPPG G C P CQ NP CH G
Sbjct: 1134 CPPGAACHHVTGA---CRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGT 1190
Query: 1601 APCRVLPEG-GAQCECPLGREGTFCQTASG 1629
C G Q CP GR G C+ G
Sbjct: 1191 CSCAAGYHGPSCQQRCPPGRYGPGCEQLCG 1220
Score = 35.8 bits (81), Expect = 0.44
Identities = 24/77 (31%), Positives = 28/77 (36%), Gaps = 13/77 (16%)
Query: 1558 CHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPN----PCHGAAPCR---VLPEGG 1610
C GA C + C CPPGR G C + C N C CR +
Sbjct: 1264 CGQGAACDPVTGT---CLCPPGRAGVRC---ERGCPQNRFGVGCEHTCSCRNGGLCHASN 1317
Query: 1611 AQCECPLGREGTFCQTA 1627
C C LG G C+ A
Sbjct: 1318 GSCSCGLGWTGRHCELA 1334
Score = 35.4 bits (80), Expect = 0.58
Identities = 19/48 (39%), Positives = 23/48 (47%), Gaps = 4/48 (8%)
Query: 1815 GHPCTRASGHPCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVEKSAG 1862
G CT G C GA+C P CLCP G +G CE+G + G
Sbjct: 1255 GPNCTHVCG--CGQGAACDP--VTGTCLCPPGRAGVRCERGCPQNRFG 1298
Score = 35.0 bits (79), Expect = 0.75
Identities = 14/28 (50%), Positives = 17/28 (60%), Gaps = 1/28 (3%)
Query: 1826 CLNGASCVPREAAYVCLCPGGFSGPHCE 1853
C +G CVP +A C CP GF GP C+
Sbjct: 133 CFHGGRCVPG-SAQPCHCPPGFQGPRCQ 159
Score = 35.0 bits (79), Expect = 0.75
Identities = 26/77 (33%), Positives = 29/77 (37%), Gaps = 13/77 (16%)
Query: 1558 CHGGAPCQNLEAGRFHCQCPPGRVGPTCADE-------KSPCQPNPCHGAAPCRVLPEGG 1610
C GA C + C CP GR GP CA+ + Q C A C P G
Sbjct: 962 CTAGAACDAVNGS---CLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCD--PVHG 1016
Query: 1611 AQCECPLGREGTFCQTA 1627
QC C G G C A
Sbjct: 1017 -QCHCAPGWMGPSCLQA 1032
Score = 35.0 bits (79), Expect = 0.75
Identities = 19/52 (36%), Positives = 23/52 (44%), Gaps = 5/52 (9%)
Query: 1817 PCTRA-SGHPCLNGASCVPREAAY----VCLCPGGFSGPHCEKGLVEKSAGD 1863
PC R G C SC P A + C CP GF+G CE+ S G+
Sbjct: 1118 PCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGE 1169
Score = 34.3 bits (77), Expect = 1.3
Identities = 17/38 (44%), Positives = 20/38 (52%), Gaps = 4/38 (10%)
Query: 1815 GHPCTRASGHPCLNGASCVPREAAYVCLCPGGFSGPHC 1852
GH C++A C NGASC P C C G+ GP C
Sbjct: 996 GHNCSQACA--CFNGASCDPVHGQ--CHCAPGWMGPSC 1029
Score = 33.5 bits (75), Expect = 2.2
Identities = 15/36 (41%), Positives = 19/36 (52%), Gaps = 4/36 (11%)
Query: 1818 CTRASGHPCLNGASCVPREAAYVCLCPGGFSGPHCE 1853
C + G CLNG C P CLCP G++G C+
Sbjct: 1085 CRHSGG--CLNGGLCDPHTGR--CLCPAGWTGDKCQ 1116
Score = 33.1 bits (74), Expect = 2.9
Identities = 22/72 (30%), Positives = 28/72 (38%), Gaps = 5/72 (6%)
Query: 1548 CGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCR-VL 1606
C C + C G C + C CPPG GP C + C+ + +G R V
Sbjct: 123 CLSAECSASLCFHGGRC--VPGSAQPCHCPPGFQGPRCQYDVDECRTH--NGGCQHRCVN 178
Query: 1607 PEGGAQCECPLG 1618
G CEC G
Sbjct: 179 TPGSYLCECKPG 190
Score = 33.1 bits (74), Expect = 2.9
Identities = 22/62 (35%), Positives = 27/62 (43%), Gaps = 5/62 (8%)
Query: 1576 CPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEG--GAQCE--CPLGREGTFCQ-TASGQ 1630
CP GR GP C Q C + P G G +CE CP R G C+ T S +
Sbjct: 1249 CPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCR 1308
Query: 1631 DG 1632
+G
Sbjct: 1309 NG 1310
Score = 32.7 bits (73), Expect = 3.7
Identities = 14/39 (35%), Positives = 20/39 (51%), Gaps = 7/39 (17%)
Query: 1816 HPCTRASGHPCLNGASCVPREAAYVCLCPGGFSGPHCEK 1854
HPC ++GH + S + CLC G+ GP CE+
Sbjct: 871 HPCNCSAGHGSCDAISGL-------CLCEAGYVGPRCEQ 902
Score = 32.3 bits (72), Expect = 4.9
Identities = 14/35 (40%), Positives = 16/35 (45%), Gaps = 3/35 (8%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCE 1367
C + CFHGG C G C CP G G C+
Sbjct: 128 CSASLCFHGGRC---VPGSAQPCHCPPGFQGPRCQ 159
Score = 32.0 bits (71), Expect = 6.4
Identities = 19/59 (32%), Positives = 26/59 (44%), Gaps = 6/59 (10%)
Query: 1546 GECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADE---KSPCQPNPCHGAA 1601
G+ G L C GGA C + C C G +GPTC + + P P+ G+A
Sbjct: 1467 GQFGPSCTLHCDCGGGADCDPVSG---QCHCVDGYMGPTCREGGPLRLPENPSLAQGSA 1522
Score = 31.6 bits (70), Expect = 8.3
Identities = 23/83 (27%), Positives = 26/83 (31%), Gaps = 9/83 (10%)
Query: 1558 CHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQ----- 1612
C G C ++ C+CPPG G C D P H C G
Sbjct: 570 CQNGGTCDSVTGA---CRCPPGVSGTNCED-GCPKGYYGKHCRKKCNCANRGRCHRLYGA 625
Query: 1613 CECPLGREGTFCQTASGQDGSGP 1635
C C G G FC GP
Sbjct: 626 CLCDPGLYGRFCHLTCPPWAFGP 648
>gi|134244285 Notch homolog 3 [Homo sapiens]
Length = 2321
Score = 127 bits (318), Expect = 1e-28
Identities = 219/904 (24%), Positives = 296/904 (32%), Gaps = 192/904 (21%)
Query: 165 PPTPPDACRGM-----LCGFGAVCEPNAEG------------PGR-ASCVCK-------- 198
PP PP R + L G GA P +G P R A+C+C
Sbjct: 17 PPPPPPPVRALPLLLLLAGPGAAAPPCLDGSPCANGGRCTQLPSREAACLCPPGWVGERC 76
Query: 199 --KSPCPSVVAPVCGSDASTYSNECELQRAQCSQQRRIRLLSRGP-CGSRDPCSNVTCSF 255
+ PC S P G S R C R R GP C DPC + C+
Sbjct: 77 QLEDPCHS--GPCAGRGVCQSSVVAGTARFSCRCPRGFR----GPDCSLPDPCLSSPCAH 130
Query: 256 GSTCARSADGLTASCLCPATCRGAPEGTVCGSDGADYPGECQLLRRACARQENVFKKFDG 315
G+ C+ DG C CP +G C SD EC+ + C + G
Sbjct: 131 GARCSVGPDG-RFLCSCPP----GYQGRSCRSD----VDECR-VGEPC--------RHGG 172
Query: 316 PCDPCQGALPDPSRSCRVNPRTRRPEMLLRPESCPARQAPVCGDDG-VTYENDCVMGRSG 374
C G+ + P P + P C R C G +TY+ C+ G G
Sbjct: 173 TCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPC--RNGGTCRQSGDLTYDCACLPGFEG 230
Query: 375 AARGLLLQKVRSGQCQGRDQCPEPCR-FNAVCLSRRGRPRCSCDRVTCDGAYRPVCAQDG 433
+ + +C C + +N C C+ D C +P +G
Sbjct: 231 QNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQ--LQPNACHNG 288
Query: 434 RTYDSDCWRQQAECRQQRAIPSKHQGPCDQAPSPCLGVQCAFGATCAVKNGQAACECLQA 493
T + C + C Q C C GATC + C C
Sbjct: 289 GTCFNTLGGHSCVC-----VNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMG 343
Query: 494 CSSLYDPVCGSDGVTYGSACELEATACT---LGREIQVA----RKGPCDR-CGQCRFGAL 545
+ L +C D + C +A T GR I G CD+ +C GA
Sbjct: 344 KTGL---LCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGAN 400
Query: 546 CEAETGRCVCPSECVALAQPVCGSDGHTYPSECMLHVHACTHQISLHVASAGPCE---TC 602
GRCV ++ L Q CG G+T P C V+ C +GPC TC
Sbjct: 401 PCEHLGRCV-NTQGSFLCQ--CGR-GYTGP-RCETDVNECL---------SGPCRNQATC 446
Query: 603 GDAVCAFGAVCSAG------QCVCPRCEHPP--PGPVCGSDGVTYGSACELREAACLQQT 654
D + F +C AG + C+ P G VC + C + Q
Sbjct: 447 LDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQL 506
Query: 655 QIEEARAGPCE------------QAECGSGGSGSGED---GDCEQELCRQRGGIWDEDSE 699
++E + PC + C G G+ D DC + C +
Sbjct: 507 DVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGRCV------ 560
Query: 700 DGPCVCDFSCQSVPGSPVCGSDGVTYSTECELKKARCESQ------RGLYVAAQGACRGP 753
DG + FSC PG T CE + C SQ + L + + CR P
Sbjct: 561 DG--IASFSCACAPGYT---------GTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCP 609
Query: 754 --TFAPLPPVAPLHCAQTP--YGCCQDNITAARGVGLAGCPSACQCNPHGSYGGTCDPAT 809
T V CA P +G C+D I C C P G G C+
Sbjct: 610 SGTTGVNCEVNIDDCASNPCTFGVCRDGINR----------YDCVCQP-GFTGPLCNVEI 658
Query: 810 GQCSCRP-GVGGLRCDRCEPGFWNFRGIVTDGRSG--CTPCS--CDPQGAVRDDCEQMTG 864
+C+ P G GG C G FR + G C P S C + C G
Sbjct: 659 NECASSPCGEGG----SCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPG 714
Query: 865 --LCSCKPGVAGPKCGQCPDGRALGPAGCEADASAPATCAEMRCEFGARCVEESGSAHCV 922
C C+PG +GP+C Q + A C C G C + HC
Sbjct: 715 GFRCVCEPGWSGPRCSQ---------------SLARDACESQPCRAGGTCSSDGMGFHCT 759
Query: 923 CPM-LTCPEANATKVCGSDGVTYGNEC-----QLKTIACRQGLQISIQSLGP-CQEAVAP 975
CP + + C + +G C QL +C QG Q GP CQ+ V
Sbjct: 760 CPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQ------GPRCQQDVDE 813
Query: 976 STHP 979
P
Sbjct: 814 CAGP 817
Score = 123 bits (308), Expect = 2e-27
Identities = 203/826 (24%), Positives = 261/826 (31%), Gaps = 176/826 (21%)
Query: 170 DACRGMLCGFGAVCEPNAEGPGRASCVCKKSPCPSVVAPVCGSDASTYS---NECE-LQR 225
DAC C A+C+ N GRA C C P C D S N CE L R
Sbjct: 353 DACVSNPCHEDAICDTNPVN-GRAICTCP----PGFTGGACDQDVDECSIGANPCEHLGR 407
Query: 226 AQCSQQRRIRLLSRGPCGSR-----DPCSNVTCSFGSTCARSADGLTASCLCPATCRGAP 280
+Q + RG G R + C + C +TC T C+ T
Sbjct: 408 CVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFT----- 462
Query: 281 EGTVCGSDGADYPGECQLLRRACARQENVFKKFDGPCDPCQGALPDPSRSCRVNPRTRRP 340
GT C D ECQ C + +G C + V+
Sbjct: 463 -GTYCEVD----IDECQ--SSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECA--- 512
Query: 341 EMLLRPESCPARQAPVCGDDGVTYENDCVMGRSGAARGLLLQKVRSGQCQGRDQC-PEPC 399
S P R C D YE C G G + D C P+PC
Sbjct: 513 -------STPCRNGAKCVDQPDGYECRCAEGFEGTLCD-----------RNVDDCSPDPC 554
Query: 400 RFNAVCLSRRGRPRCSCDRVTCDGAYRPVCAQDGRTYDSDCWRQQAECRQQRAIPSKHQG 459
RC DG CA + C Q ECR Q P +H G
Sbjct: 555 HHG----------RC------VDGIASFSCACAPGYTGTRCESQVDECRSQ---PCRHGG 595
Query: 460 PC--------DQAPSPCLGVQCAFGATCAVKNGQAACECLQACSSLYDPVCGSDGVTYGS 511
C + PS GV C N C + YD VC G T G
Sbjct: 596 KCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINR-YDCVC-QPGFT-GP 652
Query: 512 ACELEATACTLGREIQVARKGPCDRCGQCRFGALCEAETG-RCVCPSECVALAQPVCGSD 570
C +E C PC G C + E G RC+CP +
Sbjct: 653 LCNVEINECA---------SSPCGEGGSC-----VDGENGFRCLCPPGSL---------- 688
Query: 571 GHTYPSECMLHVHACTHQISLHVASAGPCE--TCGDAVCAFGAVCSAG--------QCVC 620
P C+ H C H+ PC C DA F VC G
Sbjct: 689 ----PPLCLPPSHPCAHE---------PCSHGICYDAPGGFRCVCEPGWSGPRCSQSLAR 735
Query: 621 PRCEHPP--PGPVCGSDGVTYGSACELREAACLQQTQIEEARAGPCEQAECGSGGSGSGE 678
CE P G C SDG+ + C +Q Q E PC C GG
Sbjct: 736 DACESQPCRAGGTCSSDGMGFHCTCP----PGVQGRQCE--LLSPCTPNPCEHGGRCESA 789
Query: 679 DGDCEQELCRQ--RGGIWDEDSED----GPCVCDFSCQSVPGSPVCGSDGVTYSTECELK 732
G C Q +G +D ++ PC C ++ GS C G C+
Sbjct: 790 PGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQD 849
Query: 733 KARCESQRGLYVAA-QGACRGPTFAPLPPVAPLHCAQTPYGC---------CQDNI---- 778
C+ L + Q + + LP A CA+ C C D++
Sbjct: 850 INDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGTCTDHVASFT 909
Query: 779 -TAARGVGLAGCPSAC-QCNPHGSY-GGTCDPATGQ--CSCRPGVGGLRC----DRCEPG 829
T G G C C+P + GGTC C CRPG G C D C
Sbjct: 910 CTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSR 969
Query: 830 FWNFRGIVTDGRSGCTPCSCDPQGAVRDDCEQMTGLCSCKPGVAGPKCGQ------CPDG 883
G+ + G C+C + C+ + CS +P G +C Q CP G
Sbjct: 970 PCLHGGVCSAAHPGFR-CTC-LESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPPG 1027
Query: 884 RA-----LGPAGCEADASAPATCAEMRCEFGARCVEESGSAHCVCP 924
+ + C A+ E C+ G +CV+E S +CVCP
Sbjct: 1028 WSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCP 1073
Score = 109 bits (273), Expect = 2e-23
Identities = 207/904 (22%), Positives = 272/904 (30%), Gaps = 239/904 (26%)
Query: 169 PDACRGMLCGFGAVCEPNAEG-------PGRASCVCKKSPCPSVVAPVCGSDASTYSNEC 221
PD C C GA C +G PG C+ V C T N
Sbjct: 120 PDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPC-RHGGTCLNTP 178
Query: 222 ELQRAQCSQQRRIRLLSRGPCGSRDPCSNVTCSFGSTCARSADGLTASCLC--------- 272
R QC L PC+ C G TC +S D LT C C
Sbjct: 179 GSFRCQCPAGYTGPLCENPAV----PCAPSPCRNGGTCRQSGD-LTYDCACLPGFEGQNC 233
Query: 273 -----------------------PATCRGAPEGTVCGSDGADYPGECQLLRRACARQENV 309
C+ PE T G + ECQL AC
Sbjct: 234 EVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWT--GQFCTEDVDECQLQPNACHNGGTC 291
Query: 310 FKKFDGPCDPCQGALPDPSRSCRVNPRTRRPEMLLRPESCPARQAPVCGDDGVTYENDCV 369
F G C S S ++ + C D ++ C
Sbjct: 292 FNTLGGHSCVCVNGWTGESCSQNIDDCA----------TAVCFHGATCHDRVASFYCACP 341
Query: 370 MGRSGAARGLLLQKVRSGQCQGRDQC-PEPCRFNAVCLSR--RGRPRCSCDRVTCDGAYR 426
MG++G C D C PC +A+C + GR C+C GA
Sbjct: 342 MGKTGLL------------CHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGA-- 387
Query: 427 PVCAQDGRTYDSDCWRQQAECRQQ-RAIPSK----------HQGP-CDQAPSPCLGVQCA 474
C QD +C C R + ++ + GP C+ + CL C
Sbjct: 388 --CDQDV----DECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCR 441
Query: 475 FGATCAVKNGQAACECLQACSSLYDPV----CGSDGVTYGSACE--LEATACTLGREIQV 528
ATC + GQ C C+ + Y V C S G C+ + +CT
Sbjct: 442 NQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCT------- 494
Query: 529 ARKGPCDRCGQCRFGALCEAETGRCVCPSECVALAQPVCGSDGHTYPSECMLHVHACTHQ 588
C G+ C+ + C + C A+ V DG Y C
Sbjct: 495 --------CPSGFSGSTCQLDVDECAS-TPCRNGAKCVDQPDG--YECRCAEGFEGTLCD 543
Query: 589 ISLHVASAGPCE--TCGDAVCAFGAVCSAG-----------QCVCPRCEHPPPGPVCGSD 635
++ S PC C D + +F C+ G +C C H G C
Sbjct: 544 RNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRH---GGKCLDL 600
Query: 636 GVTYGSACELREAACLQQTQIEEARAGPCEQAECGSGGSG--------------SGEDGD 681
Y C + I++ + PC C G + + E +
Sbjct: 601 VDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINE 660
Query: 682 CEQELCRQRGGIWDEDSEDGPCVCDFSCQSVPGS--PVC-----------GSDGVTYSTE 728
C C + G D E+G F C PGS P+C S G+ Y
Sbjct: 661 CASSPCGEGGSC--VDGENG-----FRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAP 713
Query: 729 ------CE-----------LKKARCESQRGLYVAAQGACRGPTFAPLPPVAPLHCAQTPY 771
CE L + CESQ A G C HC P
Sbjct: 714 GGFRCVCEPGWSGPRCSQSLARDACESQP---CRAGGTCSSDGMG-------FHCTCPP- 762
Query: 772 GCCQDNITAARGVGLAGCPSACQCNPHG-SYGGTCDPATGQ---CSCRPGVGGLRC---- 823
GV C C P+ +GG C+ A GQ CSC G G RC
Sbjct: 763 -----------GVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDV 811
Query: 824 DRCE-PGFWNFRGIVTD--GRSGCT--------PCS-----CDPQGAVRD-DCEQMTGL- 865
D C P GI T+ G CT C CDP + C+ G
Sbjct: 812 DECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSF 871
Query: 866 -CSCKPGVAGPKCGQCPDGRALGPAGCEADASAPATCAEMRCEFGARCVEESGSAHCVCP 924
CSC PG AGP+C + D C ++ P TC + F C G HC
Sbjct: 872 SCSCLPGFAGPRCARDVDE-------CLSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQD 924
Query: 925 MLTC 928
+ C
Sbjct: 925 LPDC 928
Score = 89.7 bits (221), Expect = 3e-17
Identities = 201/875 (22%), Positives = 254/875 (29%), Gaps = 236/875 (26%)
Query: 164 VPPTPPDA---CRGMLC-----GFGAVCEPNAEGP----GRASCVCKKSPCPSVVAPVCG 211
+PP+ P A C +C GF VCEP GP A C+ PC + C
Sbjct: 693 LPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRA--GGTCS 750
Query: 212 SDASTYSNECELQRAQCSQQRRIRLLSRGPCGSRDPCSNVTCSFGSTCARSADGLTASCL 271
SD + C Q R+ LLS PC+ C G C SA G C
Sbjct: 751 SDGMGFHCTCP----PGVQGRQCELLS--------PCTPNPCEHGGRC-ESAPGQLPVCS 797
Query: 272 CPATCRGAPEGTVCGSDGADYPGECQLLRRA-CARQENVFKKFDGPCDPCQGALPDPSRS 330
CP +G C D + G C F C C G PS
Sbjct: 798 CPQGWQGPR----CQQDVDECAGPAPCGPHGICTNLAGSFS-----CT-CHGGYTGPS-- 845
Query: 331 CRVNPRTRRPEMLLRPESCPARQAPVCGDDGV-TYENDCVMGRSGAARGLLLQKVRSGQC 389
C + P L SC DGV ++ C+ G +G + + S C
Sbjct: 846 CDQDINDCDPNPCLNGGSC---------QDGVGSFSCSCLPGFAGPRCARDVDECLSNPC 896
Query: 390 QGRDQCPEPCRFNAVCLSRRGRPRCSCDRVTCDGAYRPVCAQDGRTYDSDCWRQQAECRQ 449
F C G C D C P +G T CR
Sbjct: 897 GPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCS----PSSCFNGGTCVDGVNSFSCLCR- 951
Query: 450 QRAIPSKHQGPCDQAPSPCLGVQCAFGATCAVKNGQAACECLQA-----CSSLYDPVCGS 504
P C PCL C G C+ + C CL++ C +L D C
Sbjct: 952 ----PGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVD-WCSR 1006
Query: 505 DGVTYGSACELEATACTL-----GREIQVARKGPCDRCGQ---------CRFGALC--EA 548
G C C GR + R PC C+ G C E
Sbjct: 1007 QPCQNGGRCVQTGAYCLCPPGWSGRLCDI-RSLPCREAAAQIGVRLEQLCQAGGQCVDED 1065
Query: 549 ETGRCVCP-----SECV-----ALAQP-----VCGSDGHTYPSECMLHVHACTHQISLHV 593
+ CVCP S C LAQP C Y EC+ + + +
Sbjct: 1066 SSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDE 1125
Query: 594 ASAGPCE---TCGDAVCAFGAVCSAGQCVCPRCEHPPPGPVCGSDGVTYGSACELREAAC 650
++ PC+ +C D V + C PPG T G CE+ E C
Sbjct: 1126 CASQPCQHGGSCIDLVARYLCSC-------------PPG--------TLGVLCEINEDDC 1164
Query: 651 LQQTQIEEARAGPCEQAECGSGGSGSGEDGDCEQELCRQRGGIWDEDSEDGPCVCDFSCQ 710
GP + G C G D V F C
Sbjct: 1165 -----------GPGPPLDSGPR--------------CLHNGTCVD-------LVGGFRCT 1192
Query: 711 SVPGSPVCGSDGVTYSTECELKKARCESQRGLYVAAQGACRGPTFAPLPPVAPLHCAQTP 770
PG CE C S GAC C Q P
Sbjct: 1193 CPPGYT---------GLRCEADINECRS---------GACHA--------AHTRDCLQDP 1226
Query: 771 YG----CCQDNITAARGVGLAGCPSACQCNPHGSYGGTCDPATGQ-------CSCRPGVG 819
G C + R + S C+ P +GG C P+ G C C
Sbjct: 1227 GGGFRCLCHAGFSGPRCQTVL---SPCESQPC-QHGGQCRPSPGPGGGLTFTCHCAQPFW 1282
Query: 820 GLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDPQGAVRDDCEQMTGLCSCKPGVAGPKC-- 877
G RC+R + V PC P+G C+C PG++GP C
Sbjct: 1283 GPRCERVARSCRELQCPVG------VPCQQTPRGP----------RCACPPGLSGPSCRS 1326
Query: 878 ----------GQCPDGRALGPAGCEADASAP---ATCAE----MRCEFGARCVEESGSAH 920
C L C AP CA+ RCE A E S
Sbjct: 1327 FPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPR 1386
Query: 921 CVCPMLTCP----EANATKVCGSDGVTY-GNECQL 950
CP C + + C S G + G +C L
Sbjct: 1387 --CPRAACQAKRGDQRCDRECNSPGCGWDGGDCSL 1419
Score = 76.6 bits (187), Expect = 2e-13
Identities = 184/803 (22%), Positives = 242/803 (30%), Gaps = 205/803 (25%)
Query: 336 RTRRPEMLLRPESCPARQAPVCGDDGVTYENDCVMGRSGAARGLLLQKVRSGQCQGRDQC 395
R RR M P P R P+ ++ GAA L C +C
Sbjct: 9 RRRRRPMSPPPPPPPVRALPLL----------LLLAGPGAAAPPCLD---GSPCANGGRC 55
Query: 396 PEPCRFNAVCLSRRG--RPRCSCDRVTCDGAYRPVCAQDGRTYDSD-CWRQQAECRQQRA 452
+ A CL G RC + D + CA G S + CR
Sbjct: 56 TQLPSREAACLCPPGWVGERCQLE----DPCHSGPCAGRGVCQSSVVAGTARFSCR---- 107
Query: 453 IPSKHQGPCDQAPSPCLGVQCAFGATCAV-KNGQAACECL-----QACSSLYD------- 499
P +GP P PCL CA GA C+V +G+ C C ++C S D
Sbjct: 108 CPRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEP 167
Query: 500 ------------------------PVCGSDGV-------TYGSACELEA-----TACTLG 523
P+C + V G C AC G
Sbjct: 168 CRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPG 227
Query: 524 REIQVARKGPCDRCG-QCRFGALC--EAETGRCVCPSECVALAQPVCGSDGHTYPSECML 580
E Q D G +C G C T C CP E C D EC L
Sbjct: 228 FEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTG---QFCTED----VDECQL 280
Query: 581 HVHACTHQ------------ISLHVASAGPC----ETCGDAVCAFGAVC----SAGQCVC 620
+AC + + ++ + C + C AVC GA C ++ C C
Sbjct: 281 QPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCAC 340
Query: 621 P------------RCEHPP--PGPVCGSDGVTYGSACE----LREAACLQQTQIEEARAG 662
P C P +C ++ V + C AC Q A
Sbjct: 341 PMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGAN 400
Query: 663 PCEQ------------AECGSGGSG---SGEDGDCEQELCRQRGGIWDEDSEDGPCVCDF 707
PCE +CG G +G + +C CR + D + C+C
Sbjct: 401 PCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQ-FTCICMA 459
Query: 708 ------------SCQSVP--GSPVCGSDGVTYSTECELKKARCESQRGLYVAAQGACR-G 752
CQS P VC +S C + Q + A CR G
Sbjct: 460 GFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNG 519
Query: 753 PTFAPLPPVAPLHCAQTPYG-CCQDNI------TAARGVGLAGCPS-ACQCNPHGSYGGT 804
P CA+ G C N+ G + G S +C C P G G
Sbjct: 520 AKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAP-GYTGTR 578
Query: 805 CDPATGQCSCRPGVGGLRC--------DRCEPGFWNFRGIVTDGRSGCTPCSCDPQGAVR 856
C+ +C +P G +C RC G V PC+ G R
Sbjct: 579 CESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTF---GVCR 635
Query: 857 DDCEQMTGLCSCKPGVAGPKC---------------GQCPDG----RALGPAGCEADASA 897
D + C C+PG GP C G C DG R L P G
Sbjct: 636 DGINRYD--CVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCL 693
Query: 898 PAT--CAEMRCEFGARCVEESGSAHCVCPM----LTCPEANATKVCGSDGVTYGNECQLK 951
P + CA C G C + G CVC C ++ A C S G C
Sbjct: 694 PPSHPCAHEPCSHGI-CYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSD 752
Query: 952 TI----ACRQGLQ-ISIQSLGPC 969
+ C G+Q + L PC
Sbjct: 753 GMGFHCTCPPGVQGRQCELLSPC 775
Score = 64.7 bits (156), Expect = 9e-10
Identities = 30/75 (40%), Positives = 37/75 (49%), Gaps = 2/75 (2%)
Query: 1552 PCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQ-PNPCHGAAPCRVLPEGG 1610
PCL +PC GA C GRF C CPPG G +C + C+ PC C P G
Sbjct: 122 PCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTP-GS 180
Query: 1611 AQCECPLGREGTFCQ 1625
+C+CP G G C+
Sbjct: 181 FRCQCPAGYTGPLCE 195
Score = 64.7 bits (156), Expect = 9e-10
Identities = 31/73 (42%), Positives = 34/73 (46%), Gaps = 2/73 (2%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQ 1612
C PC G C + G FHC CPPG G C + SPC PNPC C P
Sbjct: 738 CESQPCRAGGTCSSDGMG-FHCTCPPGVQGRQC-ELLSPCTPNPCEHGGRCESAPGQLPV 795
Query: 1613 CECPLGREGTFCQ 1625
C CP G +G CQ
Sbjct: 796 CSCPQGWQGPRCQ 808
Score = 64.3 bits (155), Expect = 1e-09
Identities = 33/80 (41%), Positives = 43/80 (53%), Gaps = 4/80 (5%)
Query: 1550 DHPCLPNPCHGGAPCQN-LEAG--RFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVL 1606
+ PC PC G CQ+ + AG RF C+CP G GP C+ PC +PC A C V
Sbjct: 79 EDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCS-LPDPCLSSPCAHGARCSVG 137
Query: 1607 PEGGAQCECPLGREGTFCQT 1626
P+G C CP G +G C++
Sbjct: 138 PDGRFLCSCPPGYQGRSCRS 157
Score = 63.5 bits (153), Expect = 2e-09
Identities = 32/83 (38%), Positives = 37/83 (44%), Gaps = 5/83 (6%)
Query: 1543 SGVGECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAP 1602
S V EC + PC G C N G F CQCP G GP C + PC P+PC
Sbjct: 157 SDVDECR----VGEPCRHGGTCLNTP-GSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGT 211
Query: 1603 CRVLPEGGAQCECPLGREGTFCQ 1625
CR + C C G EG C+
Sbjct: 212 CRQSGDLTYDCACLPGFEGQNCE 234
Score = 61.2 bits (147), Expect = 1e-08
Identities = 81/323 (25%), Positives = 114/323 (35%), Gaps = 49/323 (15%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEKVLG--APVPAFEGRSFLAFPTLRA 1390
C S PC +GG C+D GF+C+CP+G G+ C+ + A P G + P
Sbjct: 473 CQSSPCVNGGVCKDRV--NGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPD--- 527
Query: 1391 YHTLRLALEFRALEPQGLLLYNGNARGKDFLALALLDGRVQ---LRFDTGSGPAVLTSAV 1447
E R E L + N D GR F P +
Sbjct: 528 ------GYECRCAEGFEGTLCDRNV--DDCSPDPCHHGRCVDGIASFSCACAPGYTGTRC 579
Query: 1448 PVEPGQWHRLELSRHWRRGTLSVDGETPVLGESPSGTDGLNLDTDL-------FVGGVPE 1500
+ + S+ R G +D L PSGT G+N + ++ GV
Sbjct: 580 ESQVDECR----SQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCR 635
Query: 1501 DQAAVALERTFVGAGLRGCIRLLDVNNQRLELGIGPGAATRGSGVGEC----GDHP--CL 1554
D + G G + +++N G+ G C G P CL
Sbjct: 636 D--GINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCL 693
Query: 1555 P--NPCHGGAPCQN----LEAGRFHCQCPPGRVGPTCADE--KSPCQPNPCHGAAPCRVL 1606
P +PC PC + G F C C PG GP C+ + C+ PC C
Sbjct: 694 PPSHPC-AHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCS-- 750
Query: 1607 PEG-GAQCECPLGREGTFCQTAS 1628
+G G C CP G +G C+ S
Sbjct: 751 SDGMGFHCTCPPGVQGRQCELLS 773
Score = 60.5 bits (145), Expect = 2e-08
Identities = 34/89 (38%), Positives = 40/89 (44%), Gaps = 4/89 (4%)
Query: 1550 DHPCLPNPCHGGAPCQ-NLEAGRFHCQCPPGRVGPTCADEKSPCQ--PNPCHGAAPCRVL 1606
D C+ NPCH A C N GR C CPPG G C + C NPC C V
Sbjct: 352 DDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRC-VN 410
Query: 1607 PEGGAQCECPLGREGTFCQTASGQDGSGP 1635
+G C+C G G C+T + SGP
Sbjct: 411 TQGSFLCQCGRGYTGPRCETDVNECLSGP 439
Score = 60.1 bits (144), Expect = 2e-08
Identities = 32/96 (33%), Positives = 37/96 (38%), Gaps = 8/96 (8%)
Query: 1546 GECGDH------PCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHG 1599
G G H PCL PC G C+ G + C+C PG G C D+ C PC
Sbjct: 1075 GRTGSHCEQEVDPCLAQPCQHGGTCRGYMGG-YMCECLPGYNGDNCEDDVDECASQPCQH 1133
Query: 1600 AAPCRVLPEGGAQCECPLGREGTFCQTASGQDGSGP 1635
C L C CP G G C+ G GP
Sbjct: 1134 GGSCIDL-VARYLCSCPPGTLGVLCEINEDDCGPGP 1168
Score = 57.4 bits (137), Expect = 1e-07
Identities = 35/94 (37%), Positives = 38/94 (40%), Gaps = 15/94 (15%)
Query: 1535 GPGAATRGSGVGECGDHPCLP-NPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQ 1593
GPGAA PCL +PC G C L + C CPPG VG C E PC
Sbjct: 35 GPGAAAP----------PCLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLE-DPCH 83
Query: 1594 PNPCHGAAPCRVLPEGGA---QCECPLGREGTFC 1624
PC G C+ G C CP G G C
Sbjct: 84 SGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDC 117
Score = 57.4 bits (137), Expect = 1e-07
Identities = 30/73 (41%), Positives = 33/73 (45%), Gaps = 3/73 (4%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQ 1612
C PNPC G CQ+ G F C C PG GP CA + C NPC G C
Sbjct: 853 CDPNPCLNGGSCQD-GVGSFSCSCLPGFAGPRCARDVDECLSNPC-GPGTC-TDHVASFT 909
Query: 1613 CECPLGREGTFCQ 1625
C CP G G C+
Sbjct: 910 CTCPPGYGGFHCE 922
Score = 56.2 bits (134), Expect = 3e-07
Identities = 31/80 (38%), Positives = 37/80 (46%), Gaps = 5/80 (6%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPC-HGAAPCRVLPEGGA 1611
C +PC G C + E G F C CPPG + P C PC PC HG C P GG
Sbjct: 661 CASSPCGEGGSCVDGENG-FRCLCPPGSLPPLCLPPSHPCAHEPCSHGI--CYDAP-GGF 716
Query: 1612 QCECPLGREGTFCQTASGQD 1631
+C C G G C + +D
Sbjct: 717 RCVCEPGWSGPRCSQSLARD 736
Score = 55.8 bits (133), Expect = 4e-07
Identities = 35/94 (37%), Positives = 41/94 (43%), Gaps = 7/94 (7%)
Query: 1547 ECGDHPCL---PNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGA--A 1601
+CG P L P H G C +L G F C CPPG G C + + C+ CH A
Sbjct: 1163 DCGPGPPLDSGPRCLHNGT-CVDLVGG-FRCTCPPGYTGLRCEADINECRSGACHAAHTR 1220
Query: 1602 PCRVLPEGGAQCECPLGREGTFCQTASGQDGSGP 1635
C P GG +C C G G CQT S P
Sbjct: 1221 DCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQP 1254
Score = 53.9 bits (128), Expect = 2e-06
Identities = 34/113 (30%), Positives = 46/113 (40%), Gaps = 13/113 (11%)
Query: 1534 IGPGAATRGSGVGECGD-----------HPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVG 1582
+G T+GS + +CG + CL PC A C + G+F C C G G
Sbjct: 405 LGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLD-RIGQFTCICMAGFTG 463
Query: 1583 PTCADEKSPCQPNPCHGAAPCRVLPEGGAQCECPLGREGTFCQTASGQDGSGP 1635
C + CQ +PC C+ G C CP G G+ CQ + S P
Sbjct: 464 TYCEVDIDECQSSPCVNGGVCKD-RVNGFSCTCPSGFSGSTCQLDVDECASTP 515
Score = 53.9 bits (128), Expect = 2e-06
Identities = 27/78 (34%), Positives = 33/78 (42%), Gaps = 2/78 (2%)
Query: 1558 CHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQCECPL 1617
C G C + ++ + C CP GR G C E PC PC CR GG CEC
Sbjct: 1055 CQAGGQCVDEDSSHY-CVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGY-MGGYMCECLP 1112
Query: 1618 GREGTFCQTASGQDGSGP 1635
G G C+ + S P
Sbjct: 1113 GYNGDNCEDDVDECASQP 1130
Score = 53.5 bits (127), Expect = 2e-06
Identities = 31/89 (34%), Positives = 39/89 (43%), Gaps = 9/89 (10%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPE---- 1608
C PC G C +L A R+ C CPPG +G C + C P P + P R L
Sbjct: 1126 CASQPCQHGGSCIDLVA-RYLCSCPPGTLGVLCEINEDDCGPGPPLDSGP-RCLHNGTCV 1183
Query: 1609 ---GGAQCECPLGREGTFCQTASGQDGSG 1634
GG +C CP G G C+ + SG
Sbjct: 1184 DLVGGFRCTCPPGYTGLRCEADINECRSG 1212
Score = 53.1 bits (126), Expect = 3e-06
Identities = 26/83 (31%), Positives = 33/83 (39%), Gaps = 3/83 (3%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQ 1612
C P+PCH G + + F C C PG G C + C+ PC C L +
Sbjct: 549 CSPDPCHHGRCVDGIAS--FSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVD-KYL 605
Query: 1613 CECPLGREGTFCQTASGQDGSGP 1635
C CP G G C+ S P
Sbjct: 606 CRCPSGTTGVNCEVNIDDCASNP 628
Score = 52.8 bits (125), Expect = 3e-06
Identities = 33/99 (33%), Positives = 36/99 (36%), Gaps = 15/99 (15%)
Query: 1552 PCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQ-PNPCHGAAPCRVLPEGG 1610
PC PNPC G C++ C CP G GP C + C P PC C L G
Sbjct: 774 PCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNL-AGS 832
Query: 1611 AQCECPLGREGTFCQT-------------ASGQDGSGPF 1636
C C G G C S QDG G F
Sbjct: 833 FSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSF 871
Score = 52.0 bits (123), Expect = 6e-06
Identities = 29/82 (35%), Positives = 36/82 (43%), Gaps = 6/82 (7%)
Query: 1556 NPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPC--RVLPEGGAQC 1613
NPC C N + G F CQC G GP C + + C PC A C R+ G C
Sbjct: 400 NPCEHLGRCVNTQ-GSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRI---GQFTC 455
Query: 1614 ECPLGREGTFCQTASGQDGSGP 1635
C G GT+C+ + S P
Sbjct: 456 ICMAGFTGTYCEVDIDECQSSP 477
Score = 50.8 bits (120), Expect = 1e-05
Identities = 27/77 (35%), Positives = 28/77 (36%), Gaps = 4/77 (5%)
Query: 1552 PCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGA 1611
PCL PC G C G F C C GP C C PC C + GA
Sbjct: 965 PCLSRPCLHGGVCSAAHPG-FRCTCLESFTGPQCQTLVDWCSRQPCQNGGRC---VQTGA 1020
Query: 1612 QCECPLGREGTFCQTAS 1628
C CP G G C S
Sbjct: 1021 YCLCPPGWSGRLCDIRS 1037
Score = 48.5 bits (114), Expect = 7e-05
Identities = 28/82 (34%), Positives = 34/82 (41%), Gaps = 9/82 (10%)
Query: 1545 VGECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPC--QPNPCHGAAP 1602
V +C H CL G C + ++CQCPP G C ++ C QPN CH
Sbjct: 237 VDDCPGHRCL-----NGGTCVD-GVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGT 290
Query: 1603 CRVLPEGGAQCECPLGREGTFC 1624
C GG C C G G C
Sbjct: 291 C-FNTLGGHSCVCVNGWTGESC 311
Score = 48.5 bits (114), Expect = 7e-05
Identities = 27/75 (36%), Positives = 30/75 (40%), Gaps = 4/75 (5%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPC-HGAAPCRVLPEGGA 1611
C P+ C G C + F C C PG G C E PC PC HG P G
Sbjct: 928 CSPSSCFNGGTCVD-GVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHP--GF 984
Query: 1612 QCECPLGREGTFCQT 1626
+C C G CQT
Sbjct: 985 RCTCLESFTGPQCQT 999
Score = 47.4 bits (111), Expect = 1e-04
Identities = 23/73 (31%), Positives = 28/73 (38%), Gaps = 1/73 (1%)
Query: 1552 PCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGA 1611
PC P+PC G C+ + C C PG G C C + C C V
Sbjct: 200 PCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTC-VDGVNTY 258
Query: 1612 QCECPLGREGTFC 1624
C+CP G FC
Sbjct: 259 NCQCPPEWTGQFC 271
Score = 47.0 bits (110), Expect = 2e-04
Identities = 27/83 (32%), Positives = 34/83 (40%), Gaps = 3/83 (3%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQ 1612
C PC GA C + G + C+C G G C C P+PCH C V
Sbjct: 511 CASTPCRNGAKCVDQPDG-YECRCAEGFEGTLCDRNVDDCSPDPCHHGR-C-VDGIASFS 567
Query: 1613 CECPLGREGTFCQTASGQDGSGP 1635
C C G GT C++ + S P
Sbjct: 568 CACAPGYTGTRCESQVDECRSQP 590
Score = 46.6 bits (109), Expect = 2e-04
Identities = 25/72 (34%), Positives = 29/72 (40%), Gaps = 6/72 (8%)
Query: 1555 PNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPC--RVLPEGGAQ 1612
PN CH G C N G C C G G +C+ C C A C RV
Sbjct: 282 PNACHNGGTCFNTLGGH-SCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRV---ASFY 337
Query: 1613 CECPLGREGTFC 1624
C CP+G+ G C
Sbjct: 338 CACPMGKTGLLC 349
Score = 46.6 bits (109), Expect = 2e-04
Identities = 25/73 (34%), Positives = 30/73 (41%), Gaps = 3/73 (4%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQ 1612
CL NPC G ++ + F C CPPG G C + C P+ C C V
Sbjct: 891 CLSNPCGPGTCTDHVAS--FTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTC-VDGVNSFS 947
Query: 1613 CECPLGREGTFCQ 1625
C C G G CQ
Sbjct: 948 CLCRPGYTGAHCQ 960
Score = 46.6 bits (109), Expect = 2e-04
Identities = 25/82 (30%), Positives = 31/82 (37%), Gaps = 5/82 (6%)
Query: 1552 PCLPNPCHGGAPCQNLEAG----RFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLP 1607
PC PC G C+ F C C GP C C+ C PC+ P
Sbjct: 1249 PCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTP 1308
Query: 1608 EGGAQCECPLGREGTFCQTASG 1629
G +C CP G G C++ G
Sbjct: 1309 R-GPRCACPPGLSGPSCRSFPG 1329
Score = 45.4 bits (106), Expect = 6e-04
Identities = 26/85 (30%), Positives = 29/85 (34%), Gaps = 6/85 (7%)
Query: 1547 ECGDHPCLPNPCHGG--APCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCR 1604
E + C CH C G F C C G GP C SPC+ PC CR
Sbjct: 1203 EADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCR 1262
Query: 1605 VLPEGGA----QCECPLGREGTFCQ 1625
P G C C G C+
Sbjct: 1263 PSPGPGGGLTFTCHCAQPFWGPRCE 1287
Score = 45.4 bits (106), Expect = 6e-04
Identities = 30/87 (34%), Positives = 37/87 (42%), Gaps = 6/87 (6%)
Query: 1297 PVAKTTAAPTTRRPP-TTAPS--RVPGRRPPAPQQPPKPCDSQPCFHGGTCQDWALGGGF 1353
P +T P PP + PS PG P A C + PC HGG+C+ L F
Sbjct: 1303 PCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNAS---CAAAPCLHGGSCRPAPLAPFF 1359
Query: 1354 TCSCPAGRGGAVCEKVLGAPVPAFEGR 1380
C+C G G CE AP + E R
Sbjct: 1360 RCACAQGWTGPRCEAPAAAPEVSEEPR 1386
Score = 45.1 bits (105), Expect = 7e-04
Identities = 21/48 (43%), Positives = 26/48 (54%), Gaps = 2/48 (4%)
Query: 1320 GRRPPAPQQPPKPCDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCE 1367
GR +Q PC +QPC HGGTC+ + GG+ C C G G CE
Sbjct: 1075 GRTGSHCEQEVDPCLAQPCQHGGTCRGYM--GGYMCECLPGYNGDNCE 1120
Score = 43.9 bits (102), Expect = 0.002
Identities = 25/82 (30%), Positives = 30/82 (36%), Gaps = 12/82 (14%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQ 1612
C PC G C A +C CPPG G C PC+ L + G Q
Sbjct: 1004 CSRQPCQNGGRCVQTGA---YCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQ 1060
Query: 1613 ---------CECPLGREGTFCQ 1625
C CP GR G+ C+
Sbjct: 1061 CVDEDSSHYCVCPEGRTGSHCE 1082
Score = 43.9 bits (102), Expect = 0.002
Identities = 22/40 (55%), Positives = 23/40 (57%), Gaps = 3/40 (7%)
Query: 1329 PPKPCDSQP-CFHGGTCQDWALGGGFTCSCPAGRGGAVCE 1367
P P DS P C H GTC D L GGF C+CP G G CE
Sbjct: 1166 PGPPLDSGPRCLHNGTCVD--LVGGFRCTCPPGYTGLRCE 1203
Score = 43.5 bits (101), Expect = 0.002
Identities = 20/49 (40%), Positives = 25/49 (51%), Gaps = 2/49 (4%)
Query: 1320 GRRPPAPQQPPKPCDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEK 1368
G P+ Q CD PC +GG+CQD G F+CSC G G C +
Sbjct: 840 GYTGPSCDQDINDCDPNPCLNGGSCQDGV--GSFSCSCLPGFAGPRCAR 886
Score = 43.5 bits (101), Expect = 0.002
Identities = 21/50 (42%), Positives = 26/50 (52%), Gaps = 2/50 (4%)
Query: 1318 VPGRRPPAPQQPPKPCDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCE 1367
+PG + C SQPC HGG+C D L + CSCP G G +CE
Sbjct: 1111 LPGYNGDNCEDDVDECASQPCQHGGSCID--LVARYLCSCPPGTLGVLCE 1158
Score = 42.7 bits (99), Expect = 0.004
Identities = 26/85 (30%), Positives = 32/85 (37%), Gaps = 7/85 (8%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEG--G 1610
C PC G C +L ++ C+CP G G C C NPC CR +G
Sbjct: 586 CRSQPCRHGGKCLDL-VDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGV-CR---DGINR 640
Query: 1611 AQCECPLGREGTFCQTASGQDGSGP 1635
C C G G C + S P
Sbjct: 641 YDCVCQPGFTGPLCNVEINECASSP 665
Score = 42.7 bits (99), Expect = 0.004
Identities = 22/49 (44%), Positives = 25/49 (51%), Gaps = 3/49 (6%)
Query: 1324 PAPQQPPKPCDSQPCFHGGTCQDWALGGG---FTCSCPAGRGGAVCEKV 1369
P Q PC+SQPC HGG C+ GG FTC C G CE+V
Sbjct: 1241 PRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERV 1289
Score = 42.4 bits (98), Expect = 0.005
Identities = 22/46 (47%), Positives = 25/46 (54%), Gaps = 4/46 (8%)
Query: 1336 QPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEK--VLGAPVPAFEG 1379
+PC HGGTC + G F C CPAG G +CE V AP P G
Sbjct: 166 EPCRHGGTCLNTP--GSFRCQCPAGYTGPLCENPAVPCAPSPCRNG 209
Score = 42.4 bits (98), Expect = 0.005
Identities = 22/52 (42%), Positives = 24/52 (46%), Gaps = 3/52 (5%)
Query: 1319 PGRRPPAPQQPPKPCDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEKVL 1370
PG PP P PC +PC H G C D GGF C C G G C + L
Sbjct: 685 PGSLPPLCLPPSHPCAHEPCSH-GICYD--APGGFRCVCEPGWSGPRCSQSL 733
Score = 42.4 bits (98), Expect = 0.005
Identities = 25/72 (34%), Positives = 36/72 (50%), Gaps = 9/72 (12%)
Query: 1813 FAGHPCTR----ASGHPCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVEKSAGDVDTLA 1868
FAG C R +PC G +C A++ C CP G+ G HCE+ L + S
Sbjct: 879 FAGPRCARDVDECLSNPCGPG-TCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSS----C 933
Query: 1869 FDGRTFVEYLNA 1880
F+G T V+ +N+
Sbjct: 934 FNGGTCVDGVNS 945
Score = 40.4 bits (93), Expect = 0.018
Identities = 36/119 (30%), Positives = 42/119 (35%), Gaps = 23/119 (19%)
Query: 1268 GATARATTASRLPSSAVTPRAPHPSHTSQPVAKTTAAPTTRRPPTT--APSRVPGRRPPA 1325
G AR R P S P P P + P+ A P PP +P GR
Sbjct: 2 GPGARGRRRRRRPMS---PPPPPPPVRALPLLLLLAGPGAAAPPCLDGSPCANGGRCTQL 58
Query: 1326 PQQ------PP----------KPCDSQPCFHGGTCQDWALGG--GFTCSCPAGRGGAVC 1366
P + PP PC S PC G CQ + G F+C CP G G C
Sbjct: 59 PSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDC 117
Score = 40.4 bits (93), Expect = 0.018
Identities = 14/35 (40%), Positives = 21/35 (60%)
Query: 1823 GHPCLNGASCVPREAAYVCLCPGGFSGPHCEKGLV 1857
G PC +G +C+ ++ C CP G++GP CE V
Sbjct: 165 GEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAV 199
Score = 39.7 bits (91), Expect = 0.031
Identities = 26/66 (39%), Positives = 31/66 (46%), Gaps = 5/66 (7%)
Query: 1316 SRVPGRRPPAPQQPPKPCDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEKVLG--AP 1373
S +PG P + C S PC GTC D FTC+CP G GG CE+ L +P
Sbjct: 874 SCLPGFAGPRCARDVDECLSNPC-GPGTCTDHV--ASFTCTCPPGYGGFHCEQDLPDCSP 930
Query: 1374 VPAFEG 1379
F G
Sbjct: 931 SSCFNG 936
Score = 39.3 bits (90), Expect = 0.040
Identities = 18/37 (48%), Positives = 18/37 (48%), Gaps = 1/37 (2%)
Query: 1330 PKPCDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVC 1366
P PC S PC HG C G F CSCP G G C
Sbjct: 120 PDPCLSSPCAHGARC-SVGPDGRFLCSCPPGYQGRSC 155
Score = 39.3 bits (90), Expect = 0.040
Identities = 17/50 (34%), Positives = 24/50 (48%), Gaps = 4/50 (8%)
Query: 1811 TSFAGHPCT----RASGHPCLNGASCVPREAAYVCLCPGGFSGPHCEKGL 1856
+ F+G C + PC NGA CV + Y C C GF G C++ +
Sbjct: 497 SGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNV 546
Score = 39.3 bits (90), Expect = 0.040
Identities = 15/35 (42%), Positives = 21/35 (60%)
Query: 1824 HPCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVE 1858
+PCLNG SC ++ C C GF+GP C + + E
Sbjct: 856 NPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDE 890
Score = 38.9 bits (89), Expect = 0.052
Identities = 14/34 (41%), Positives = 21/34 (61%)
Query: 1825 PCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVE 1858
PC N A+C+ R + C+C GF+G +CE + E
Sbjct: 439 PCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDE 472
Score = 38.9 bits (89), Expect = 0.052
Identities = 14/29 (48%), Positives = 17/29 (58%)
Query: 1825 PCLNGASCVPREAAYVCLCPGGFSGPHCE 1853
PC+NG C R + C CP GFSG C+
Sbjct: 477 PCVNGGVCKDRVNGFSCTCPSGFSGSTCQ 505
Score = 38.5 bits (88), Expect = 0.068
Identities = 15/34 (44%), Positives = 19/34 (55%), Gaps = 2/34 (5%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVC 1366
C + CFHG TC D F C+CP G+ G +C
Sbjct: 318 CATAVCFHGATCHDRV--ASFYCACPMGKTGLLC 349
Score = 38.5 bits (88), Expect = 0.068
Identities = 19/52 (36%), Positives = 24/52 (46%), Gaps = 2/52 (3%)
Query: 1319 PGRRPPAPQQPPKPCDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEKVL 1370
PG Q PC S+PC HGG C A GF C+C G C+ ++
Sbjct: 952 PGYTGAHCQHEADPCLSRPCLHGGVCS--AAHPGFRCTCLESFTGPQCQTLV 1001
Score = 38.1 bits (87), Expect = 0.089
Identities = 22/56 (39%), Positives = 27/56 (48%), Gaps = 5/56 (8%)
Query: 1313 TAPSRVPGRRPPAPQQPPKPCDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEK 1368
T P V GR+ + PC PC HGG C+ A G CSCP G G C++
Sbjct: 759 TCPPGVQGRQC----ELLSPCTPNPCEHGGRCES-APGQLPVCSCPQGWQGPRCQQ 809
Score = 37.7 bits (86), Expect = 0.12
Identities = 22/71 (30%), Positives = 31/71 (43%), Gaps = 10/71 (14%)
Query: 1791 VSLGGRQLLTPEHVLRQVDVTSFAGHPCTRASGHP-------CLNGASCVPREAAYVCLC 1843
V G L P R D+ S PC A+ C G CV ++++ C+C
Sbjct: 1016 VQTGAYCLCPPGWSGRLCDIRSL---PCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVC 1072
Query: 1844 PGGFSGPHCEK 1854
P G +G HCE+
Sbjct: 1073 PEGRTGSHCEQ 1083
Score = 37.0 bits (84), Expect = 0.20
Identities = 15/36 (41%), Positives = 20/36 (55%)
Query: 1823 GHPCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVE 1858
GH CLNG +CV Y C CP ++G C + + E
Sbjct: 242 GHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDE 277
Score = 36.6 bits (83), Expect = 0.26
Identities = 15/41 (36%), Positives = 22/41 (53%)
Query: 1822 SGHPCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVEKSAG 1862
SG CL+ +CV + C CP G++G CE + E +G
Sbjct: 1172 SGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSG 1212
Score = 36.6 bits (83), Expect = 0.26
Identities = 21/48 (43%), Positives = 26/48 (54%), Gaps = 6/48 (12%)
Query: 1812 SFAGHP--CTRAS--GHPCLNGASCVPREAA--YVCLCPGGFSGPHCE 1853
SF G P + AS PCL+G SC P A + C C G++GP CE
Sbjct: 1326 SFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCE 1373
Score = 36.2 bits (82), Expect = 0.34
Identities = 20/43 (46%), Positives = 22/43 (51%), Gaps = 7/43 (16%)
Query: 1814 AGHPCTRASGHPCLNGASCVP---REAAYVCLCPGGFSGPHCE 1853
A PC G PC NG C REAA CLCP G+ G C+
Sbjct: 39 AAPPCL--DGSPCANGGRCTQLPSREAA--CLCPPGWVGERCQ 77
Score = 36.2 bits (82), Expect = 0.34
Identities = 12/28 (42%), Positives = 18/28 (64%)
Query: 1826 CLNGASCVPREAAYVCLCPGGFSGPHCE 1853
C NG +CV ++ CLC G++G HC+
Sbjct: 933 CFNGGTCVDGVNSFSCLCRPGYTGAHCQ 960
Score = 36.2 bits (82), Expect = 0.34
Identities = 21/46 (45%), Positives = 24/46 (52%), Gaps = 6/46 (13%)
Query: 1812 SFAGHPCTR----ASGHPCLNGASCVPREAAYVCLCPGGFSGPHCE 1853
SF G C S PC NG CV + AY CLCP G+SG C+
Sbjct: 991 SFTGPQCQTLVDWCSRQPCQNGGRCV-QTGAY-CLCPPGWSGRLCD 1034
Score = 36.2 bits (82), Expect = 0.34
Identities = 14/32 (43%), Positives = 18/32 (56%)
Query: 1822 SGHPCLNGASCVPREAAYVCLCPGGFSGPHCE 1853
+ PC +G SC+ A Y+C CP G G CE
Sbjct: 1127 ASQPCQHGGSCIDLVARYLCSCPPGTLGVLCE 1158
Score = 35.8 bits (81), Expect = 0.44
Identities = 31/92 (33%), Positives = 33/92 (35%), Gaps = 15/92 (16%)
Query: 1534 IGPGAATRGSGVGECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQ 1593
+GPGA RG P P P P L AG PG P C D
Sbjct: 1 MGPGA--RGRRRRRRPMSPPPPPPPVRALPLLLLLAG-------PGAAAPPCLDG----- 46
Query: 1594 PNPCHGAAPCRVLPEGGAQCECPLGREGTFCQ 1625
+PC C LP A C CP G G CQ
Sbjct: 47 -SPCANGGRCTQLPSREAACLCPPGWVGERCQ 77
Score = 35.0 bits (79), Expect = 0.75
Identities = 19/50 (38%), Positives = 23/50 (46%), Gaps = 5/50 (10%)
Query: 1320 GRRPPAPQQPPKPCDSQPCFHGGTCQDWALGGGFT--CSCPAGRGGAVCE 1367
G P + P PC PC +GGTC+ G T C+C G G CE
Sbjct: 188 GYTGPLCENPAVPCAPSPCRNGGTCRQ---SGDLTYDCACLPGFEGQNCE 234
Score = 35.0 bits (79), Expect = 0.75
Identities = 13/39 (33%), Positives = 23/39 (58%)
Query: 1824 HPCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVEKSAG 1862
+PC + CV + +++C C G++GP CE + E +G
Sbjct: 400 NPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSG 438
Score = 35.0 bits (79), Expect = 0.75
Identities = 16/41 (39%), Positives = 20/41 (48%), Gaps = 2/41 (4%)
Query: 1327 QQPPKPCDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCE 1367
+Q C CF+GGTC D F+C C G GA C+
Sbjct: 922 EQDLPDCSPSSCFNGGTCVDGV--NSFSCLCRPGYTGAHCQ 960
Score = 34.7 bits (78), Expect = 0.98
Identities = 12/29 (41%), Positives = 17/29 (58%)
Query: 1825 PCLNGASCVPREAAYVCLCPGGFSGPHCE 1853
PC +G C+ Y+C CP G +G +CE
Sbjct: 590 PCRHGGKCLDLVDKYLCRCPSGTTGVNCE 618
Score = 34.7 bits (78), Expect = 0.98
Identities = 18/48 (37%), Positives = 20/48 (41%), Gaps = 2/48 (4%)
Query: 1319 PGRRPPAPQQPPKPCDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVC 1366
PG P C S PC GG+C D GF C CP G +C
Sbjct: 647 PGFTGPLCNVEINECASSPCGEGGSCVDGE--NGFRCLCPPGSLPPLC 692
Score = 34.3 bits (77), Expect = 1.3
Identities = 15/41 (36%), Positives = 20/41 (48%), Gaps = 4/41 (9%)
Query: 1816 HPCTRASGHPCLNGASCVPREAAYVCLCPGGFSGPHCEKGL 1856
HPC PC +G C + C+C G+SGP C + L
Sbjct: 697 HPCAH---EPCSHGI-CYDAPGGFRCVCEPGWSGPRCSQSL 733
Score = 33.9 bits (76), Expect = 1.7
Identities = 16/48 (33%), Positives = 24/48 (50%), Gaps = 4/48 (8%)
Query: 1817 PCTRASGHPCLNGASC-VPREAAYVCLCPGGFSGPHCEKGLVEKSAGD 1863
PC + PC +GA C V + ++C CP G+ G C + E G+
Sbjct: 122 PCLSS---PCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGE 166
Score = 33.9 bits (76), Expect = 1.7
Identities = 17/44 (38%), Positives = 19/44 (43%), Gaps = 4/44 (9%)
Query: 1813 FAGHPCT----RASGHPCLNGASCVPREAAYVCLCPGGFSGPHC 1852
F G C + PC G SCV E + CLCP G P C
Sbjct: 649 FTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLC 692
Score = 33.5 bits (75), Expect = 2.2
Identities = 18/47 (38%), Positives = 25/47 (53%), Gaps = 5/47 (10%)
Query: 1817 PCTRASGHPCLNGASCVPREAAY-VCLCPGGFSGPHCEKGLVEKSAG 1862
PCT +PC +G C VC CP G+ GP C++ V++ AG
Sbjct: 774 PCTP---NPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQD-VDECAG 816
Score = 33.1 bits (74), Expect = 2.9
Identities = 19/48 (39%), Positives = 21/48 (43%), Gaps = 2/48 (4%)
Query: 1320 GRRPPAPQQPPKPCDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCE 1367
G P + C S PC + TC D G FTC C AG G CE
Sbjct: 422 GYTGPRCETDVNECLSGPCRNQATCLDRI--GQFTCICMAGFTGTYCE 467
Score = 33.1 bits (74), Expect = 2.9
Identities = 12/38 (31%), Positives = 16/38 (42%)
Query: 1816 HPCTRASGHPCLNGASCVPREAAYVCLCPGGFSGPHCE 1853
H PCL+G C + C C F+GP C+
Sbjct: 961 HEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQ 998
Score = 33.1 bits (74), Expect = 2.9
Identities = 18/59 (30%), Positives = 27/59 (45%), Gaps = 10/59 (16%)
Query: 1800 TPEHVLRQVDVTSFAGHPCTRASGHPCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVE 1858
T H ++VD PC PC +G +C Y+C C G++G +CE + E
Sbjct: 1077 TGSHCEQEVD-------PCL---AQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDE 1125
Score = 32.7 bits (73), Expect = 3.7
Identities = 14/35 (40%), Positives = 18/35 (51%), Gaps = 4/35 (11%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCE 1367
C QPC +GG C + G C CP G G +C+
Sbjct: 1004 CSRQPCQNGGRC----VQTGAYCLCPPGWSGRLCD 1034
Score = 32.3 bits (72), Expect = 4.9
Identities = 14/39 (35%), Positives = 19/39 (48%), Gaps = 1/39 (2%)
Query: 1816 HPCTRASGHPCLNGASCVPR-EAAYVCLCPGGFSGPHCE 1853
+P + PC NG +C + Y C C GF G +CE
Sbjct: 196 NPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCE 234
Score = 32.3 bits (72), Expect = 4.9
Identities = 16/49 (32%), Positives = 25/49 (51%), Gaps = 4/49 (8%)
Query: 1808 VDVTSFAGHPCTR----ASGHPCLNGASCVPREAAYVCLCPGGFSGPHC 1852
V V + G C++ + C +GA+C R A++ C CP G +G C
Sbjct: 301 VCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLC 349
Score = 32.3 bits (72), Expect = 4.9
Identities = 12/36 (33%), Positives = 16/36 (44%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEK 1368
C S PC C + G C+CP G G C++
Sbjct: 355 CVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQ 390
Score = 32.3 bits (72), Expect = 4.9
Identities = 24/78 (30%), Positives = 34/78 (43%), Gaps = 11/78 (14%)
Query: 1313 TAPSRVP------GRRPPAPQQPPKPCDSQ-PCFHGGTCQDWALGGGFTCSCPAGRGGAV 1365
+AP ++P G + P QQ C PC G C + L G F+C+C G G
Sbjct: 788 SAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTN--LAGSFSCTCHGGYTGPS 845
Query: 1366 CEKVLG--APVPAFEGRS 1381
C++ + P P G S
Sbjct: 846 CDQDINDCDPNPCLNGGS 863
>gi|5453652 follistatin isoform FST317 precursor [Homo sapiens]
Length = 317
Score = 122 bits (306), Expect = 4e-27
Identities = 84/231 (36%), Positives = 104/231 (45%), Gaps = 31/231 (13%)
Query: 537 CGQCRFGALCEAETGRCVCPSEC--VALAQPVCGSDGHTYPSECMLHVHACTHQISLHVA 594
CG + + + RCVC +C + PVCG DG TY +EC L C Q L V
Sbjct: 100 CGPGKKCRMNKKNKPRCVCAPDCSNITWKGPVCGLDGKTYRNECALLKARCKEQPELEVQ 159
Query: 595 SAGPCE-TCGDAVCAFGAVCSAGQ---CVCPRCEHPPPGP------VCGSDGVTYGSACE 644
G C+ TC D C + C Q C C P P +CG+DGVTY SAC
Sbjct: 160 YQGRCKKTCRDVFCPGSSTCVVDQTNNAYCVTCNRICPEPASSEQYLCGNDGVTYSSACH 219
Query: 645 LREAACLQQTQIEEARAGPCEQAECGSGGSGSGEDGDCEQELCRQRGG---IWDEDSEDG 701
LR+A CL I A G C +A+ CE C GG +WD G
Sbjct: 220 LRKATCLLGRSIGLAYEGKCIKAK------------SCEDIQC--TGGKKCLWDFKVGRG 265
Query: 702 PC-VCDFSC-QSVPGSPVCGSDGVTYSTECELKKARCESQRGLYVAAQGAC 750
C +CD C S PVC SD TY++EC +K+A C S L V G+C
Sbjct: 266 RCSLCDELCPDSKSDEPVCASDNATYASECAMKEAACSSGVLLEVKHSGSC 316
Score = 120 bits (300), Expect = 2e-26
Identities = 80/233 (34%), Positives = 111/233 (47%), Gaps = 33/233 (14%)
Query: 389 CQGRDQCP-EPCRFNAVCLSRRGRPRC----SCDRVTCDGAYRPVCAQDGRTYDSDCWRQ 443
C+ D P + CR N ++ +PRC C +T G PVC DG+TY ++C
Sbjct: 95 CENVDCGPGKKCRMN-----KKNKPRCVCAPDCSNITWKG---PVCGLDGKTYRNECALL 146
Query: 444 QAECRQQRAIPSKHQGPCDQAPSPCLGVQCAFGATCAVK--NGQAACECLQAC---SSLY 498
+A C++Q + ++QG C + C V C +TC V N C + C +S
Sbjct: 147 KARCKEQPELEVQYQGRCKKT---CRDVFCPGSSTCVVDQTNNAYCVTCNRICPEPASSE 203
Query: 499 DPVCGSDGVTYGSACELEATACTLGREIQVARKGPCDRCG-----QCRFGALC----EAE 549
+CG+DGVTY SAC L C LGR I +A +G C + QC G C +
Sbjct: 204 QYLCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKCIKAKSCEDIQCTGGKKCLWDFKVG 263
Query: 550 TGRC-VCPSEC--VALAQPVCGSDGHTYPSECMLHVHACTHQISLHVASAGPC 599
GRC +C C +PVC SD TY SEC + AC+ + L V +G C
Sbjct: 264 RGRCSLCDELCPDSKSDEPVCASDNATYASECAMKEAACSSGVLLEVKHSGSC 316
Score = 114 bits (284), Expect = 1e-24
Identities = 69/231 (29%), Positives = 106/231 (45%), Gaps = 18/231 (7%)
Query: 170 DACRGMLCGFGAVCEPNAEGPGRASCVCKKSPCPSVV--APVCGSDASTYSNECELQRAQ 227
+ C + CG G C N + R CVC C ++ PVCG D TY NEC L +A+
Sbjct: 93 ETCENVDCGPGKKCRMNKKNKPR--CVCAPD-CSNITWKGPVCGLDGKTYRNECALLKAR 149
Query: 228 CSQQRRIRLLSRGPCGSRDPCSNVTCSFGSTC----ARSADGLTASCLCPATCRGAPEGT 283
C +Q + + +G C + C +V C STC +A +T + +CP + E
Sbjct: 150 CKEQPELEVQYQGRC--KKTCRDVFCPGSSTCVVDQTNNAYCVTCNRICPEP--ASSEQY 205
Query: 284 VCGSDGADYPGECQLLRRACARQENVFKKFDGPC---DPCQGALPDPSRSCRVNPRTRRP 340
+CG+DG Y C L + C ++ ++G C C+ + C + + R
Sbjct: 206 LCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKCIKAKSCEDIQCTGGKKCLWDFKVGRG 265
Query: 341 EMLLRPESCPARQA--PVCGDDGVTYENDCVMGRSGAARGLLLQKVRSGQC 389
L E CP ++ PVC D TY ++C M + + G+LL+ SG C
Sbjct: 266 RCSLCDELCPDSKSDEPVCASDNATYASECAMKEAACSSGVLLEVKHSGSC 316
Score = 105 bits (261), Expect = 6e-22
Identities = 71/232 (30%), Positives = 104/232 (44%), Gaps = 14/232 (6%)
Query: 241 PCGSRDPCSNVTCSFGSTCARSADGLTASCLCPATCRGAP-EGTVCGSDGADYPGECQLL 299
PC ++ C NV C G C + C+C C +G VCG DG Y EC LL
Sbjct: 90 PC--KETCENVDCGPGKKCRMNKKN-KPRCVCAPDCSNITWKGPVCGLDGKTYRNECALL 146
Query: 300 RRACARQENVFKKFDGPC-DPCQGALPDPSRSCRVNPRTRRPEMLLRPESCP---ARQAP 355
+ C Q + ++ G C C+ S +C V+ +T + CP + +
Sbjct: 147 KARCKEQPELEVQYQGRCKKTCRDVFCPGSSTCVVD-QTNNAYCVTCNRICPEPASSEQY 205
Query: 356 VCGDDGVTYENDCVMGRSGAARGLLLQKVRSGQCQGRDQCPE-PCRFNAVCL--SRRGRP 412
+CG+DGVTY + C + ++ G + G+C C + C CL + GR
Sbjct: 206 LCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKCIKAKSCEDIQCTGGKKCLWDFKVGRG 265
Query: 413 RCS-CDRVTCDG-AYRPVCAQDGRTYDSDCWRQQAECRQQRAIPSKHQGPCD 462
RCS CD + D + PVCA D TY S+C ++A C + KH G C+
Sbjct: 266 RCSLCDELCPDSKSDEPVCASDNATYASECAMKEAACSSGVLLEVKHSGSCN 317
Score = 102 bits (254), Expect = 4e-21
Identities = 72/238 (30%), Positives = 110/238 (46%), Gaps = 28/238 (11%)
Query: 316 PC-DPCQGALPDPSRSCRVNPRTRRPEMLLRPE-SCPARQAPVCGDDGVTYENDCVMGRS 373
PC + C+ P + CR+N + + P + P+ S + PVCG DG TY N+C + ++
Sbjct: 90 PCKETCENVDCGPGKKCRMNKKNK-PRCVCAPDCSNITWKGPVCGLDGKTYRNECALLKA 148
Query: 374 GAARGLLLQKVRSGQCQ---------GRDQCPEPCRFNAVCLSRRGRPRCSCDRVTCDGA 424
L+ G+C+ G C NA C++ C+R+ + A
Sbjct: 149 RCKEQPELEVQYQGRCKKTCRDVFCPGSSTCVVDQTNNAYCVT--------CNRICPEPA 200
Query: 425 YRP--VCAQDGRTYDSDCWRQQAECRQQRAIPSKHQGPCDQAPSPCLGVQCAFGATCA-- 480
+C DG TY S C ++A C R+I ++G C +A S C +QC G C
Sbjct: 201 SSEQYLCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKCIKAKS-CEDIQCTGGKKCLWD 259
Query: 481 VKNGQAACE-CLQAC--SSLYDPVCGSDGVTYGSACELEATACTLGREIQVARKGPCD 535
K G+ C C + C S +PVC SD TY S C ++ AC+ G ++V G C+
Sbjct: 260 FKVGRGRCSLCDELCPDSKSDEPVCASDNATYASECAMKEAACSSGVLLEVKHSGSCN 317
Score = 81.6 bits (200), Expect = 7e-15
Identities = 53/164 (32%), Positives = 73/164 (44%), Gaps = 25/164 (15%)
Query: 598 PC-ETCGDAVCAFGAVCSAGQCVCPRCEHPP-------PGPVCGSDGVTYGSACELREAA 649
PC ETC + C G C + PRC P GPVCG DG TY + C L +A
Sbjct: 90 PCKETCENVDCGPGKKCRMNKKNKPRCVCAPDCSNITWKGPVCGLDGKTYRNECALLKAR 149
Query: 650 CLQQTQIEEARAGPCEQAECGSGGSGSGEDGDCEQELCRQRGGIWDEDSEDGPCV-CDFS 708
C +Q ++E G C++ C C + + + CV C+
Sbjct: 150 CKEQPELEVQYQGRCKKT--------------CRDVFCPGSSTCVVDQTNNAYCVTCNRI 195
Query: 709 CQSVPGSP--VCGSDGVTYSTECELKKARCESQRGLYVAAQGAC 750
C S +CG+DGVTYS+ C L+KA C R + +A +G C
Sbjct: 196 CPEPASSEQYLCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKC 239
Score = 73.2 bits (178), Expect = 2e-12
Identities = 76/311 (24%), Positives = 113/311 (36%), Gaps = 94/311 (30%)
Query: 664 CEQAECGSGGSGSGEDGDCEQELCRQRGGIWDEDSEDGP-CVCDFSCQSVPGS-PVCGSD 721
CE +CG G + CR + ++ P CVC C ++ PVCG D
Sbjct: 95 CENVDCGPG------------KKCRM-------NKKNKPRCVCAPDCSNITWKGPVCGLD 135
Query: 722 GVTYSTECELKKARCESQRGLYVAAQGACRGPTFAPLPPVAPLHCAQTPYGCCQDNITAA 781
G TY EC L KARC+ Q L V QG C +T C+D
Sbjct: 136 GKTYRNECALLKARCKEQPELEVQYQG----------------RCKKT----CRDVF--- 172
Query: 782 RGVGLAGCPSACQCNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGR 841
CP + C + C + C+R P
Sbjct: 173 -------CPGSSTCVVDQTNNAYC---------------VTCNRICP------------- 197
Query: 842 SGCTPCSCDPQGAVRDDCEQMTGLCSCKPGVAGPKCGQCPDGRALGPAGCEADASAPATC 901
P S + Q +D + C + C GR++G A E +C
Sbjct: 198 ---EPASSE-QYLCGNDGVTYSSACHLRKAT-------CLLGRSIGLA-YEGKCIKAKSC 245
Query: 902 AEMRCEFGARCVEES--GSAHCVCPMLTCPEANATK-VCGSDGVTYGNECQLKTIACRQG 958
+++C G +C+ + G C CP++ + + VC SD TY +EC +K AC G
Sbjct: 246 EDIQCTGGKKCLWDFKVGRGRCSLCDELCPDSKSDEPVCASDNATYASECAMKEAACSSG 305
Query: 959 LQISIQSLGPC 969
+ + ++ G C
Sbjct: 306 VLLEVKHSGSC 316
Score = 72.8 bits (177), Expect = 3e-12
Identities = 47/155 (30%), Positives = 66/155 (42%), Gaps = 13/155 (8%)
Query: 172 CRGMLCGFGAVCEPNAEGPGRASCVCKKSPCPSVVAP---VCGSDASTYSNECELQRAQC 228
CR + C + C + A CV CP + +CG+D TYS+ C L++A C
Sbjct: 168 CRDVFCPGSSTCV--VDQTNNAYCVTCNRICPEPASSEQYLCGNDGVTYSSACHLRKATC 225
Query: 229 SQQRRIRLLSRGPCGSRDPCSNVTCSFGSTCA---RSADGLTASC--LCPATCRGAPEGT 283
R I L G C C ++ C+ G C + G + C LCP + P
Sbjct: 226 LLGRSIGLAYEGKCIKAKSCEDIQCTGGKKCLWDFKVGRGRCSLCDELCPDSKSDEP--- 282
Query: 284 VCGSDGADYPGECQLLRRACARQENVFKKFDGPCD 318
VC SD A Y EC + AC+ + K G C+
Sbjct: 283 VCASDNATYASECAMKEAACSSGVLLEVKHSGSCN 317
Score = 57.8 bits (138), Expect = 1e-07
Identities = 47/166 (28%), Positives = 70/166 (42%), Gaps = 32/166 (19%)
Query: 836 IVTDGRSGCTPCS-------CDPQGAVRDDCEQMTGLCSCKPGVA-----GPKCGQCPDG 883
I G C PC C P R + ++ C C P + GP CG DG
Sbjct: 80 IFNGGAPNCIPCKETCENVDCGPGKKCRMN-KKNKPRCVCAPDCSNITWKGPVCGL--DG 136
Query: 884 R------ALGPAGCEADASAPA--------TCAEMRCEFGARCV-EESGSAHCVCPMLTC 928
+ AL A C+ TC ++ C + CV +++ +A+CV C
Sbjct: 137 KTYRNECALLKARCKEQPELEVQYQGRCKKTCRDVFCPGSSTCVVDQTNNAYCVTCNRIC 196
Query: 929 PEANATK--VCGSDGVTYGNECQLKTIACRQGLQISIQSLGPCQEA 972
PE +++ +CG+DGVTY + C L+ C G I + G C +A
Sbjct: 197 PEPASSEQYLCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKCIKA 242
Score = 47.0 bits (110), Expect = 2e-04
Identities = 26/88 (29%), Positives = 39/88 (44%), Gaps = 1/88 (1%)
Query: 900 TCAEMRCEFGARC-VEESGSAHCVCPMLTCPEANATKVCGSDGVTYGNECQLKTIACRQG 958
TC + C G +C + + CVC VCG DG TY NEC L C++
Sbjct: 94 TCENVDCGPGKKCRMNKKNKPRCVCAPDCSNITWKGPVCGLDGKTYRNECALLKARCKEQ 153
Query: 959 LQISIQSLGPCQEAVAPSTHPTSASVTV 986
++ +Q G C++ P S++ V
Sbjct: 154 PELEVQYQGRCKKTCRDVFCPGSSTCVV 181
>gi|7242222 follistatin isoform FST344 precursor [Homo sapiens]
Length = 344
Score = 122 bits (306), Expect = 4e-27
Identities = 84/231 (36%), Positives = 104/231 (45%), Gaps = 31/231 (13%)
Query: 537 CGQCRFGALCEAETGRCVCPSEC--VALAQPVCGSDGHTYPSECMLHVHACTHQISLHVA 594
CG + + + RCVC +C + PVCG DG TY +EC L C Q L V
Sbjct: 100 CGPGKKCRMNKKNKPRCVCAPDCSNITWKGPVCGLDGKTYRNECALLKARCKEQPELEVQ 159
Query: 595 SAGPCE-TCGDAVCAFGAVCSAGQ---CVCPRCEHPPPGP------VCGSDGVTYGSACE 644
G C+ TC D C + C Q C C P P +CG+DGVTY SAC
Sbjct: 160 YQGRCKKTCRDVFCPGSSTCVVDQTNNAYCVTCNRICPEPASSEQYLCGNDGVTYSSACH 219
Query: 645 LREAACLQQTQIEEARAGPCEQAECGSGGSGSGEDGDCEQELCRQRGG---IWDEDSEDG 701
LR+A CL I A G C +A+ CE C GG +WD G
Sbjct: 220 LRKATCLLGRSIGLAYEGKCIKAK------------SCEDIQC--TGGKKCLWDFKVGRG 265
Query: 702 PC-VCDFSC-QSVPGSPVCGSDGVTYSTECELKKARCESQRGLYVAAQGAC 750
C +CD C S PVC SD TY++EC +K+A C S L V G+C
Sbjct: 266 RCSLCDELCPDSKSDEPVCASDNATYASECAMKEAACSSGVLLEVKHSGSC 316
Score = 120 bits (302), Expect = 1e-26
Identities = 80/238 (33%), Positives = 113/238 (47%), Gaps = 33/238 (13%)
Query: 389 CQGRDQCP-EPCRFNAVCLSRRGRPRC----SCDRVTCDGAYRPVCAQDGRTYDSDCWRQ 443
C+ D P + CR N ++ +PRC C +T G PVC DG+TY ++C
Sbjct: 95 CENVDCGPGKKCRMN-----KKNKPRCVCAPDCSNITWKG---PVCGLDGKTYRNECALL 146
Query: 444 QAECRQQRAIPSKHQGPCDQAPSPCLGVQCAFGATCAVK--NGQAACECLQAC---SSLY 498
+A C++Q + ++QG C + C V C +TC V N C + C +S
Sbjct: 147 KARCKEQPELEVQYQGRCKKT---CRDVFCPGSSTCVVDQTNNAYCVTCNRICPEPASSE 203
Query: 499 DPVCGSDGVTYGSACELEATACTLGREIQVARKGPCDRCG-----QCRFGALC----EAE 549
+CG+DGVTY SAC L C LGR I +A +G C + QC G C +
Sbjct: 204 QYLCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKCIKAKSCEDIQCTGGKKCLWDFKVG 263
Query: 550 TGRC-VCPSEC--VALAQPVCGSDGHTYPSECMLHVHACTHQISLHVASAGPCETCGD 604
GRC +C C +PVC SD TY SEC + AC+ + L V +G C + +
Sbjct: 264 RGRCSLCDELCPDSKSDEPVCASDNATYASECAMKEAACSSGVLLEVKHSGSCNSISE 321
Score = 114 bits (284), Expect = 1e-24
Identities = 69/231 (29%), Positives = 106/231 (45%), Gaps = 18/231 (7%)
Query: 170 DACRGMLCGFGAVCEPNAEGPGRASCVCKKSPCPSVV--APVCGSDASTYSNECELQRAQ 227
+ C + CG G C N + R CVC C ++ PVCG D TY NEC L +A+
Sbjct: 93 ETCENVDCGPGKKCRMNKKNKPR--CVCAPD-CSNITWKGPVCGLDGKTYRNECALLKAR 149
Query: 228 CSQQRRIRLLSRGPCGSRDPCSNVTCSFGSTC----ARSADGLTASCLCPATCRGAPEGT 283
C +Q + + +G C + C +V C STC +A +T + +CP + E
Sbjct: 150 CKEQPELEVQYQGRC--KKTCRDVFCPGSSTCVVDQTNNAYCVTCNRICPEP--ASSEQY 205
Query: 284 VCGSDGADYPGECQLLRRACARQENVFKKFDGPC---DPCQGALPDPSRSCRVNPRTRRP 340
+CG+DG Y C L + C ++ ++G C C+ + C + + R
Sbjct: 206 LCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKCIKAKSCEDIQCTGGKKCLWDFKVGRG 265
Query: 341 EMLLRPESCPARQA--PVCGDDGVTYENDCVMGRSGAARGLLLQKVRSGQC 389
L E CP ++ PVC D TY ++C M + + G+LL+ SG C
Sbjct: 266 RCSLCDELCPDSKSDEPVCASDNATYASECAMKEAACSSGVLLEVKHSGSC 316
Score = 105 bits (262), Expect = 5e-22
Identities = 75/247 (30%), Positives = 102/247 (41%), Gaps = 27/247 (10%)
Query: 461 CDQAPSPCLGVQCAFGATCAV-KNGQAACECLQACSSLY--DPVCGSDGVTYGSACELEA 517
C C V C G C + K + C C CS++ PVCG DG TY + C L
Sbjct: 88 CIPCKETCENVDCGPGKKCRMNKKNKPRCVCAPDCSNITWKGPVCGLDGKTYRNECALLK 147
Query: 518 TACTLGREIQVARKGPCDRCGQ---CRFGALCEAE--------TGRCVCPSECVALAQPV 566
C E++V +G C + + C + C + T +CP E + Q +
Sbjct: 148 ARCKEQPELEVQYQGRCKKTCRDVFCPGSSTCVVDQTNNAYCVTCNRICP-EPASSEQYL 206
Query: 567 CGSDGHTYPSECMLHVHACTHQISLHVASAGPC---ETCGDAVCAFGAVC----SAGQCV 619
CG+DG TY S C L C S+ +A G C ++C D C G C G+
Sbjct: 207 CGNDGVTYSSACHLRKATCLLGRSIGLAYEGKCIKAKSCEDIQCTGGKKCLWDFKVGRGR 266
Query: 620 CPRCEHPPPG-----PVCGSDGVTYGSACELREAACLQQTQIEEARAGPCEQAECGSGGS 674
C C+ P PVC SD TY S C ++EAAC +E +G C +
Sbjct: 267 CSLCDELCPDSKSDEPVCASDNATYASECAMKEAACSSGVLLEVKHSGSCNSISEDTEEE 326
Query: 675 GSGEDGD 681
ED D
Sbjct: 327 EEDEDQD 333
Score = 105 bits (261), Expect = 6e-22
Identities = 71/232 (30%), Positives = 104/232 (44%), Gaps = 14/232 (6%)
Query: 241 PCGSRDPCSNVTCSFGSTCARSADGLTASCLCPATCRGAP-EGTVCGSDGADYPGECQLL 299
PC ++ C NV C G C + C+C C +G VCG DG Y EC LL
Sbjct: 90 PC--KETCENVDCGPGKKCRMNKKN-KPRCVCAPDCSNITWKGPVCGLDGKTYRNECALL 146
Query: 300 RRACARQENVFKKFDGPC-DPCQGALPDPSRSCRVNPRTRRPEMLLRPESCP---ARQAP 355
+ C Q + ++ G C C+ S +C V+ +T + CP + +
Sbjct: 147 KARCKEQPELEVQYQGRCKKTCRDVFCPGSSTCVVD-QTNNAYCVTCNRICPEPASSEQY 205
Query: 356 VCGDDGVTYENDCVMGRSGAARGLLLQKVRSGQCQGRDQCPE-PCRFNAVCL--SRRGRP 412
+CG+DGVTY + C + ++ G + G+C C + C CL + GR
Sbjct: 206 LCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKCIKAKSCEDIQCTGGKKCLWDFKVGRG 265
Query: 413 RCS-CDRVTCDG-AYRPVCAQDGRTYDSDCWRQQAECRQQRAIPSKHQGPCD 462
RCS CD + D + PVCA D TY S+C ++A C + KH G C+
Sbjct: 266 RCSLCDELCPDSKSDEPVCASDNATYASECAMKEAACSSGVLLEVKHSGSCN 317
Score = 73.2 bits (178), Expect = 2e-12
Identities = 76/311 (24%), Positives = 113/311 (36%), Gaps = 94/311 (30%)
Query: 664 CEQAECGSGGSGSGEDGDCEQELCRQRGGIWDEDSEDGP-CVCDFSCQSVPGS-PVCGSD 721
CE +CG G + CR + ++ P CVC C ++ PVCG D
Sbjct: 95 CENVDCGPG------------KKCRM-------NKKNKPRCVCAPDCSNITWKGPVCGLD 135
Query: 722 GVTYSTECELKKARCESQRGLYVAAQGACRGPTFAPLPPVAPLHCAQTPYGCCQDNITAA 781
G TY EC L KARC+ Q L V QG C +T C+D
Sbjct: 136 GKTYRNECALLKARCKEQPELEVQYQG----------------RCKKT----CRDVF--- 172
Query: 782 RGVGLAGCPSACQCNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGR 841
CP + C + C + C+R P
Sbjct: 173 -------CPGSSTCVVDQTNNAYC---------------VTCNRICP------------- 197
Query: 842 SGCTPCSCDPQGAVRDDCEQMTGLCSCKPGVAGPKCGQCPDGRALGPAGCEADASAPATC 901
P S + Q +D + C + C GR++G A E +C
Sbjct: 198 ---EPASSE-QYLCGNDGVTYSSACHLRKAT-------CLLGRSIGLA-YEGKCIKAKSC 245
Query: 902 AEMRCEFGARCVEES--GSAHCVCPMLTCPEANATK-VCGSDGVTYGNECQLKTIACRQG 958
+++C G +C+ + G C CP++ + + VC SD TY +EC +K AC G
Sbjct: 246 EDIQCTGGKKCLWDFKVGRGRCSLCDELCPDSKSDEPVCASDNATYASECAMKEAACSSG 305
Query: 959 LQISIQSLGPC 969
+ + ++ G C
Sbjct: 306 VLLEVKHSGSC 316
Score = 72.8 bits (177), Expect = 3e-12
Identities = 47/155 (30%), Positives = 66/155 (42%), Gaps = 13/155 (8%)
Query: 172 CRGMLCGFGAVCEPNAEGPGRASCVCKKSPCPSVVAP---VCGSDASTYSNECELQRAQC 228
CR + C + C + A CV CP + +CG+D TYS+ C L++A C
Sbjct: 168 CRDVFCPGSSTCV--VDQTNNAYCVTCNRICPEPASSEQYLCGNDGVTYSSACHLRKATC 225
Query: 229 SQQRRIRLLSRGPCGSRDPCSNVTCSFGSTCA---RSADGLTASC--LCPATCRGAPEGT 283
R I L G C C ++ C+ G C + G + C LCP + P
Sbjct: 226 LLGRSIGLAYEGKCIKAKSCEDIQCTGGKKCLWDFKVGRGRCSLCDELCPDSKSDEP--- 282
Query: 284 VCGSDGADYPGECQLLRRACARQENVFKKFDGPCD 318
VC SD A Y EC + AC+ + K G C+
Sbjct: 283 VCASDNATYASECAMKEAACSSGVLLEVKHSGSCN 317
Score = 57.8 bits (138), Expect = 1e-07
Identities = 47/166 (28%), Positives = 70/166 (42%), Gaps = 32/166 (19%)
Query: 836 IVTDGRSGCTPCS-------CDPQGAVRDDCEQMTGLCSCKPGVA-----GPKCGQCPDG 883
I G C PC C P R + ++ C C P + GP CG DG
Sbjct: 80 IFNGGAPNCIPCKETCENVDCGPGKKCRMN-KKNKPRCVCAPDCSNITWKGPVCGL--DG 136
Query: 884 R------ALGPAGCEADASAPA--------TCAEMRCEFGARCV-EESGSAHCVCPMLTC 928
+ AL A C+ TC ++ C + CV +++ +A+CV C
Sbjct: 137 KTYRNECALLKARCKEQPELEVQYQGRCKKTCRDVFCPGSSTCVVDQTNNAYCVTCNRIC 196
Query: 929 PEANATK--VCGSDGVTYGNECQLKTIACRQGLQISIQSLGPCQEA 972
PE +++ +CG+DGVTY + C L+ C G I + G C +A
Sbjct: 197 PEPASSEQYLCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKCIKA 242
Score = 47.0 bits (110), Expect = 2e-04
Identities = 26/88 (29%), Positives = 39/88 (44%), Gaps = 1/88 (1%)
Query: 900 TCAEMRCEFGARC-VEESGSAHCVCPMLTCPEANATKVCGSDGVTYGNECQLKTIACRQG 958
TC + C G +C + + CVC VCG DG TY NEC L C++
Sbjct: 94 TCENVDCGPGKKCRMNKKNKPRCVCAPDCSNITWKGPVCGLDGKTYRNECALLKARCKEQ 153
Query: 959 LQISIQSLGPCQEAVAPSTHPTSASVTV 986
++ +Q G C++ P S++ V
Sbjct: 154 PELEVQYQGRCKKTCRDVFCPGSSTCVV 181
Score = 42.7 bits (99), Expect = 0.004
Identities = 24/75 (32%), Positives = 36/75 (48%), Gaps = 1/75 (1%)
Query: 171 ACRGMLCGFGAVCEPNAE-GPGRASCVCKKSPCPSVVAPVCGSDASTYSNECELQRAQCS 229
+C + C G C + + G GR S + P PVC SD +TY++EC ++ A CS
Sbjct: 244 SCEDIQCTGGKKCLWDFKVGRGRCSLCDELCPDSKSDEPVCASDNATYASECAMKEAACS 303
Query: 230 QQRRIRLLSRGPCGS 244
+ + G C S
Sbjct: 304 SGVLLEVKHSGSCNS 318
>gi|4759146 slit homolog 2 [Homo sapiens]
Length = 1529
Score = 122 bits (305), Expect = 5e-27
Identities = 96/314 (30%), Positives = 133/314 (42%), Gaps = 34/314 (10%)
Query: 1323 PPAPQQPPKPCDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEKVLGAPVPAFEGRSF 1382
PP PCD+ C +G C C C G G CEK++ V S+
Sbjct: 1115 PPMVLPRTSPCDNFDCQNGAQCI--VRINEPICQCLPGYQGEKCEKLVS--VNFINKESY 1170
Query: 1383 LAFPTLRAYHTLRLALEFRALEPQGLLLYNGNARGKDFLALALLDGRVQLRFDTGSGPA- 1441
L P+ + + L+ E G+LLY G+ KD +A+ L GRV+ +DTGS PA
Sbjct: 1171 LQIPSAKVRPQTNITLQIATDEDSGILLYKGD---KDHIAVELYRGRVRASYDTGSHPAS 1227
Query: 1442 VLTSAVPVEPGQWHRLELSRHWRRGTLSVDGETPVLGESPSGTDGLNLDTDLFVGGVPED 1501
+ S + G +H +EL + +LSVDG P + + S LN D+ L+VGG+P
Sbjct: 1228 AIYSVETINDGNFHIVELLALDQSLSLSVDGGNPKIITNLSKQSTLNFDSPLYVGGMPGK 1287
Query: 1502 QAAVALERT--FVGAGLRGCIRLLDVNNQ-------RLELGIGPGAATRGSGVGECGDHP 1552
+L + G GCIR L +N++ ++ GI PG P
Sbjct: 1288 SNVASLRQAPGQNGTSFHGCIRNLYINSELQDFQKVPMQTGILPGC------------EP 1335
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADE-KSPCQPNPC-HGAAPCRVLPEGG 1610
C C G CQ F C+C G +GP C PC N C HG C +
Sbjct: 1336 CHKKVCAHGT-CQPSSQAGFTCECQEGWMGPLCDQRTNDPCLGNKCVHGT--CLPINAFS 1392
Query: 1611 AQCECPLGREGTFC 1624
C+C G G C
Sbjct: 1393 YSCKCLEGHGGVLC 1406
Score = 74.7 bits (182), Expect = 9e-13
Identities = 88/338 (26%), Positives = 128/338 (37%), Gaps = 52/338 (15%)
Query: 1556 NPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQCEC 1615
NPC + C G F C C PG VG C + CQ N C A C G C C
Sbjct: 1045 NPCQHDSKCILTPKG-FKCDCTPGYVGEHCDIDFDDCQDNKCKNGAHCTDAVNGYT-CIC 1102
Query: 1616 PLGREGTF--------------CQTASGQDGSG-------PFLADFNGFSHLELRGLHTF 1654
P G G F C Q+G+ P G+ + L +
Sbjct: 1103 PEGYSGLFCEFSPPMVLPRTSPCDNFDCQNGAQCIVRINEPICQCLPGYQGEKCEKLVS- 1161
Query: 1655 ARDLGEKMALEVVFLARGP-------------SGLLLYNGQKTDGKGDFVSLALRDRRLE 1701
+ ++ L++ P SG+LLY G K D +++ L R+
Sbjct: 1162 VNFINKESYLQIPSAKVRPQTNITLQIATDEDSGILLYKGDK-----DHIAVELYRGRVR 1216
Query: 1702 FRYDLGKG-AAVIRSREPVTLGAWTRVSLERNGRKGALRVGDGPRVLGESPVPHTVLNLK 1760
YD G A+ I S E + G + V L + +L V G + + + LN
Sbjct: 1217 ASYDTGSHPASAIYSVETINDGNFHIVELLALDQSLSLSVDGGNPKIITNLSKQSTLNFD 1276
Query: 1761 EPLYVGGAPDFSKLA--RAAAVSSG--FDGAIQLVSLGGRQLLTPEHVLRQVDVTSFAGH 1816
PLYVGG P S +A R A +G F G I+ + + +L + V Q +
Sbjct: 1277 SPLYVGGMPGKSNVASLRQAPGQNGTSFHGCIRNLYINS-ELQDFQKVPMQTGILP-GCE 1334
Query: 1817 PCTRASGHPCLNGASCVPREAAYVCLCPGGFSGPHCEK 1854
PC + C +G +A + C C G+ GP C++
Sbjct: 1335 PCHK---KVCAHGTCQPSSQAGFTCECQEGWMGPLCDQ 1369
Score = 63.5 bits (153), Expect = 2e-09
Identities = 54/203 (26%), Positives = 93/203 (45%), Gaps = 25/203 (12%)
Query: 1826 CLNGASCVPREAAYVCLCPGGFSGPHCEKGLVEKSAGDVDTLAFDGRTFVEYLNAVTESE 1885
C NGA C+ R +C C G+ G CEK LV + + ++ YL S
Sbjct: 1130 CQNGAQCIVRINEPICQCLPGYQGEKCEK-LVSVNFINKES----------YLQ--IPSA 1176
Query: 1886 KALQSNHFELSLRTEATQGLVLWSGKATERADYVALAIVDGHLQLSYNLGSQPV-VLRST 1944
K + L + T+ G++L+ G D++A+ + G ++ SY+ GS P + S
Sbjct: 1177 KVRPQTNITLQIATDEDSGILLYKGD----KDHIAVELYRGRVRASYDTGSHPASAIYSV 1232
Query: 1945 VPVNTNRW--LRVVAHREQREGSLQVGNEAPVTGSSPLGATQLDTDGALWLGGLPELPVG 2002
+N + + ++A + S+ GN +T S + L+ D L++GG+P
Sbjct: 1233 ETINDGNFHIVELLALDQSLSLSVDGGNPKIITNLSK--QSTLNFDSPLYVGGMPGKSNV 1290
Query: 2003 PAL---PKAYGTGFVGCLRDVVV 2022
+L P GT F GC+R++ +
Sbjct: 1291 ASLRQAPGQNGTSFHGCIRNLYI 1313
Score = 51.2 bits (121), Expect = 1e-05
Identities = 26/77 (33%), Positives = 31/77 (40%), Gaps = 2/77 (2%)
Query: 1551 HPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVL--PE 1608
+PCL NPC C + + C CP G G C C NPC C + E
Sbjct: 920 NPCLSNPCKNDGTCNSDPVDFYRCTCPYGFKGQDCDVPIHACISNPCKHGGTCHLKEGEE 979
Query: 1609 GGAQCECPLGREGTFCQ 1625
G C C G EG C+
Sbjct: 980 DGFWCICADGFEGENCE 996
Score = 46.6 bits (109), Expect = 2e-04
Identities = 43/150 (28%), Positives = 56/150 (37%), Gaps = 23/150 (15%)
Query: 792 ACQCNPHGSYGGTCDPATGQ-----CSCRPGVGGLRC----DRCEPGFWNFRGIVTDGRS 842
AC NP +GGTC G+ C C G G C D CE DG +
Sbjct: 960 ACISNPC-KHGGTCHLKEGEEDGFWCICADGFEGENCEVNVDDCEDNDCENNSTCVDGIN 1018
Query: 843 GCTPCSCDPQGAVRDDCEQMTGLCS--CKPGVAGPKCGQCPDGRAL----GPAG--CEAD 894
T C C P+ + CE+ C+ P KC P G G G C+ D
Sbjct: 1019 NYT-CLCPPE-YTGELCEEKLDFCAQDLNPCQHDSKCILTPKGFKCDCTPGYVGEHCDID 1076
Query: 895 ASAPATCAEMRCEFGARCVEESGSAHCVCP 924
C + +C+ GA C + C+CP
Sbjct: 1077 FD---DCQDNKCKNGAHCTDAVNGYTCICP 1103
Score = 43.5 bits (101), Expect = 0.002
Identities = 24/77 (31%), Positives = 28/77 (36%), Gaps = 3/77 (3%)
Query: 1551 HPCLPNPCHGGAPCQNLEAGR--FHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPE 1608
H C+ NPC G C E F C C G G C C+ N C + C V
Sbjct: 959 HACISNPCKHGGTCHLKEGEEDGFWCICADGFEGENCEVNVDDCEDNDCENNSTC-VDGI 1017
Query: 1609 GGAQCECPLGREGTFCQ 1625
C CP G C+
Sbjct: 1018 NNYTCLCPPEYTGELCE 1034
Score = 42.4 bits (98), Expect = 0.005
Identities = 22/74 (29%), Positives = 32/74 (43%), Gaps = 4/74 (5%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQP--NPCHGAAPCRVLPEGG 1610
C N C + C + + C CPP G C ++ C NPC + C + P+ G
Sbjct: 1002 CEDNDCENNSTCVD-GINNYTCLCPPEYTGELCEEKLDFCAQDLNPCQHDSKCILTPK-G 1059
Query: 1611 AQCECPLGREGTFC 1624
+C+C G G C
Sbjct: 1060 FKCDCTPGYVGEHC 1073
Score = 36.2 bits (82), Expect = 0.34
Identities = 43/172 (25%), Positives = 60/172 (34%), Gaps = 48/172 (27%)
Query: 758 LPPVAPLHCAQTPYGCCQDNITAARGVGLAGCPSACQ---------------CNPHGSYG 802
LP P H +G CQ + AG CQ C +
Sbjct: 1330 LPGCEPCHKKVCAHGTCQPS-------SQAGFTCECQEGWMGPLCDQRTNDPCLGNKCVH 1382
Query: 803 GTCDPATG---QCSCRPGVGGLRCD------------RCEPGFWNFRGI---VTDGRSGC 844
GTC P C C G GG+ CD +C+ G G+ + SG
Sbjct: 1383 GTCLPINAFSYSCKCLEGHGGVLCDEEEDLFNPCQAIKCKHGKCRLSGLGQPYCECSSGY 1442
Query: 845 TPCSCDPQ-----GAVRDDCEQMTGLCSCK--PGVAGPKC-GQCPDGRALGP 888
T SCD + +RD ++ G +C+ V+ +C G C G+ GP
Sbjct: 1443 TGDSCDREISCRGERIRDYYQKQQGYAACQTTKKVSRLECRGGCAGGQCCGP 1494
Score = 34.3 bits (77), Expect = 1.3
Identities = 18/40 (45%), Positives = 18/40 (45%), Gaps = 1/40 (2%)
Query: 1329 PPKPCDSQPCFHGGTCQ-DWALGGGFTCSCPAGRGGAVCE 1367
P C S PC HGGTC GF C C G G CE
Sbjct: 957 PIHACISNPCKHGGTCHLKEGEEDGFWCICADGFEGENCE 996
Score = 33.5 bits (75), Expect = 2.2
Identities = 66/301 (21%), Positives = 88/301 (29%), Gaps = 85/301 (28%)
Query: 599 CETCGDAVCAFGAVCSAG-----QCVCPR------CEHPPPGPVCGSDGVTYGSACELRE 647
C C C C++ +C CP C+ P C S+ +G C L+E
Sbjct: 919 CNPCLSNPCKNDGTCNSDPVDFYRCTCPYGFKGQDCDVPIHA--CISNPCKHGGTCHLKE 976
Query: 648 AACLQQTQIEEARAGPCEQAECGSGGSGSGEDGDCEQELCRQRGGIWDEDSEDGPCVCDF 707
E C C G G +CE + +D ED C +
Sbjct: 977 G---------EEDGFWCI---CADGFEGE----NCEVNV---------DDCEDNDCENNS 1011
Query: 708 SCQSVPGSPVCGSDGVTYSTECELKKARCESQRGLYVAAQGACRGPTFAPLPPVAPLHCA 767
+C V G + T E CE + C+ + L P C
Sbjct: 1012 TC-------VDGINNYTCLCPPEYTGELCEEKLDFCAQDLNPCQHDSKCILTPKG-FKCD 1063
Query: 768 QTP----------YGCCQDNITAARGVGLAGCPSACQCNPHGSYGGTCDPATGQ-CSCRP 816
TP + CQDN C + C D G C C
Sbjct: 1064 CTPGYVGEHCDIDFDDCQDN----------KCKNGAHCT---------DAVNGYTCICPE 1104
Query: 817 GVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDPQGAVRDDCEQMTGLCSCKPGVAGPK 876
G GL C+ P +V S C C Q + +C C PG G K
Sbjct: 1105 GYSGLFCEFSPP-------MVLPRTSPCDNFDC--QNGAQCIVRINEPICQCLPGYQGEK 1155
Query: 877 C 877
C
Sbjct: 1156 C 1156
Score = 33.1 bits (74), Expect = 2.9
Identities = 35/135 (25%), Positives = 45/135 (33%), Gaps = 40/135 (29%)
Query: 847 CSCDPQGAVRDDCEQMTGLCSCKPGVAGPKC----GQ-------CPDGRALGPAGCEADA 895
C+C P G DC+ C P G C G+ C DG CE +
Sbjct: 943 CTC-PYGFKGQDCDVPIHACISNPCKHGGTCHLKEGEEDGFWCICADG--FEGENCEVNV 999
Query: 896 SAPATCAEMRCEFGARCVEESGSAHCVCPMLTCPEANATKVCGSDGVTYGNECQLKTIAC 955
C + CE + CV+ + C+CP PE Y E C
Sbjct: 1000 D---DCEDNDCENNSTCVDGINNYTCLCP----PE-------------YTGEL------C 1033
Query: 956 RQGLQISIQSLGPCQ 970
+ L Q L PCQ
Sbjct: 1034 EEKLDFCAQDLNPCQ 1048
Score = 32.3 bits (72), Expect = 4.9
Identities = 13/31 (41%), Positives = 18/31 (58%)
Query: 1826 CLNGASCVPREAAYVCLCPGGFSGPHCEKGL 1856
C N ++CV Y CLCP ++G CE+ L
Sbjct: 1007 CENNSTCVDGINNYTCLCPPEYTGELCEEKL 1037
Score = 32.3 bits (72), Expect = 4.9
Identities = 22/74 (29%), Positives = 33/74 (44%), Gaps = 9/74 (12%)
Query: 421 CDGAYRPVCAQDGRTYDSDCWRQQAECRQQRAIPSKHQGP-CDQAPS-PCLGVQCAFGAT 478
C+ ++ VCA G S EC++ GP CDQ + PCLG +C G
Sbjct: 1333 CEPCHKKVCAH-GTCQPSSQAGFTCECQEG------WMGPLCDQRTNDPCLGNKCVHGTC 1385
Query: 479 CAVKNGQAACECLQ 492
+ +C+CL+
Sbjct: 1386 LPINAFSYSCKCLE 1399
Score = 32.0 bits (71), Expect = 6.4
Identities = 18/69 (26%), Positives = 31/69 (44%), Gaps = 7/69 (10%)
Query: 1817 PCTRASGHPCLNGASCVPREA---AYVCLCPGGFSGPHCEKGLVEKSAGDVDTLAFDGRT 1873
P +PC +G +C +E + C+C GF G +CE + + D + + T
Sbjct: 957 PIHACISNPCKHGGTCHLKEGEEDGFWCICADGFEGENCEVNVDDCEDNDCE----NNST 1012
Query: 1874 FVEYLNAVT 1882
V+ +N T
Sbjct: 1013 CVDGINNYT 1021
>gi|165932370 FAT tumor suppressor homolog 4 [Homo sapiens]
Length = 4981
Score = 119 bits (297), Expect = 4e-26
Identities = 135/535 (25%), Positives = 206/535 (38%), Gaps = 84/535 (15%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQ 1612
CLP+PCH G C NL G F C CP G G C + + C +PC A C+ P G
Sbjct: 3866 CLPSPCHSGGTCHNLVGG-FSCSCPDGFTGRACERDINECLQSPCKNGAICQNFP-GSFN 3923
Query: 1613 CECPLGREGTFCQTASGQDGSGPFLADFNGFS-------------------HLELRGLHT 1653
C C G G C+++ P FNG S H EL
Sbjct: 3924 CVCKTGYTGKMCESSVNYCECNPC---FNGGSCQSGVDSYYCHCPFGVFGKHCELNSYGF 3980
Query: 1654 FARDLGEKMALE-------VVFLARGPSGLLLYN-GQKTDGKGDFVSLALRDRRLEFRYD 1705
E +L+ V F LLLYN +T + +F++L + + RL F Y+
Sbjct: 3981 EELSYMEFPSLDPNNNYIYVKFATIKSHALLLYNYDNQTGDRAEFLALEIAEERLRFSYN 4040
Query: 1706 LGKGAAVIRSREPVTLGAWTRVSLERNGRKGALRVGDGPRVLGESPVPHTVLNL------ 1759
LG G + + + V+ G + V R G +L V + P TV N+
Sbjct: 4041 LGSGTYKLTTMKKVSDGHFHTVIARRAGMAASLTVDSCSE--NQEPGYCTVSNVAVSDDW 4098
Query: 1760 -----KEPLYVGGAPDFSKL--ARAAAVSSGFDGAIQLVSLGGRQLLTPEHVLRQ--VDV 1810
+ VGG + R S F G I ++ GR L + + Q +D
Sbjct: 4099 TLDVQPNRVTVGGIRSLEPILQRRGHVESHDFVGCIMEFAVNGRPLEPSQALAAQGILDQ 4158
Query: 1811 TSFAGHPCTRASGHPCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVEKSAGDVDTLAFD 1870
CTR+ PC +G +C+ + C C G +G +CEK + +A L+ +
Sbjct: 4159 CPRLEGACTRS---PCQHGGTCMDYWSWQQCHCKEGLTGKYCEKSVTPDTA-----LSLE 4210
Query: 1871 GRTFVEYLNAVTESEKAL--QS-----------NHFELSLRTEATQGLVLWSGKATERAD 1917
G+ ++Y + E + L QS N E+ RT + G+++ E ++
Sbjct: 4211 GKGRLDYHMSQNEKREYLLRQSLRGAMLEPFGVNSLEVKFRTRSENGVLI---HIQESSN 4267
Query: 1918 YVALAIVDGHLQLSYNLGSQPVVLRS--TVPVNTNRWLRVVAHREQREGSLQVG---NEA 1972
Y + I +G + + + G V R+ V V W + + L V N
Sbjct: 4268 YTTVKIKNGKVYFTSDAGIAGKVERNIPEVYVADGHWHTFLIGKNGTATVLSVDRIYNRD 4327
Query: 1973 PVTGSSPLGATQLDTDGALWLGGLPELPVGPALPKAYGTGFVGCLRDVVVGRHPL 2027
+ + G + T + LGG+P A A GF GC+ + G L
Sbjct: 4328 IIHPTQDFGGLDVLT---ISLGGIPP---NQAHRDAQTAGFDGCIASMWYGGESL 4376
Score = 109 bits (273), Expect = 2e-23
Identities = 142/577 (24%), Positives = 224/577 (38%), Gaps = 111/577 (19%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEKVLGAPVPAFEGRSFLAFPTLRAYH 1392
C+ PCF+GG+CQ + C CP G G CE FE S++ FP+L +
Sbjct: 3942 CECNPCFNGGSCQSGV--DSYYCHCPFGVFGKHCE----LNSYGFEELSYMEFPSLDPNN 3995
Query: 1393 TLRLALEFRALEPQGLLLYNGNARGKD---FLALALLDGRVQLRFDTGSGPAVLTSAVPV 1449
+ ++F ++ LLLYN + + D FLAL + + R++ ++ GSG LT+ V
Sbjct: 3996 NY-IYVKFATIKSHALLLYNYDNQTGDRAEFLALEIAEERLRFSYNLGSGTYKLTTMKKV 4054
Query: 1450 EPGQWHRLELSRHWRRGTLSVD--GETPVLG----ESPSGTDGLNLDTD---LFVGGVPE 1500
G +H + R +L+VD E G + + +D LD + VGG+
Sbjct: 4055 SDGHFHTVIARRAGMAASLTVDSCSENQEPGYCTVSNVAVSDDWTLDVQPNRVTVGGIRS 4114
Query: 1501 DQAAVALERTFVGAGLRGCIRLLDVNNQRLELGIGPGAATRGSGV-GECG--DHPCLPNP 1557
+ + GCI VN + LE P A G+ +C + C +P
Sbjct: 4115 LEPILQRRGHVESHDFVGCIMEFAVNGRPLE----PSQALAAQGILDQCPRLEGACTRSP 4170
Query: 1558 CHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQCECPL 1617
C G C + + + C C G G C EKS V P+ E
Sbjct: 4171 CQHGGTCMDYWSWQ-QCHCKEGLTGKYC--EKS--------------VTPDTALSLE--- 4210
Query: 1618 GREGTFCQTASGQDGSGPFLADFNGFSHLELRGLHTFARDLGEKMALEVVFLARGPSGLL 1677
+G S + L + LE G++ +LEV F R +G+L
Sbjct: 4211 -GKGRLDYHMSQNEKREYLLRQSLRGAMLEPFGVN----------SLEVKFRTRSENGVL 4259
Query: 1678 LYNGQKTDGKGDFVSLALRDRRLEFRYDLGKGAAVIRSREPVTL--GAWTRVSLERNGRK 1735
++ + + ++ ++ +++ ++ F D G V R+ V + G W + +NG
Sbjct: 4260 IHIQESS----NYTTVKIKNGKVYFTSDAGIAGKVERNIPEVYVADGHWHTFLIGKNGTA 4315
Query: 1736 GALRVGDGPRVLGESPVPHT-------VLNLKEPLYVGGAPDFSKLARAAAVSSGFDGAI 1788
L V R+ + T VL + +GG P A A ++GFDG I
Sbjct: 4316 TVLSV---DRIYNRDIIHPTQDFGGLDVLTIS----LGGIP--PNQAHRDAQTAGFDGCI 4366
Query: 1789 QLVSLGGRQL-LTPEHVLRQVDVTS------------FAGHPC----------------- 1818
+ GG L + +H L + T A +PC
Sbjct: 4367 ASMWYGGESLPFSGKHSLASISKTDPSVKIGCRGPNICASNPCWGDLLCINQWYAYRCVP 4426
Query: 1819 -TRASGHPCLNGASCVP-REAAYVCLCPGGFSGPHCE 1853
+ HPC NG SC P + + C CP +G CE
Sbjct: 4427 PGDCASHPCQNGGSCEPGLHSGFTCSCPDSHTGRTCE 4463
Score = 71.6 bits (174), Expect = 7e-12
Identities = 62/249 (24%), Positives = 103/249 (41%), Gaps = 32/249 (12%)
Query: 1811 TSFAGHPCTRASGH----PCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVEKSAGDVDT 1866
T + G C + + PC NG SC +Y C CP G G HCE +++
Sbjct: 3928 TGYTGKMCESSVNYCECNPCFNGGSCQSGVDSYYCHCPFGVFGKHCE----------LNS 3977
Query: 1867 LAFDGRTFVEYLNAVTESEKALQSNHFELSLRTEATQGLVLWS--GKATERADYVALAIV 1924
F+ +++E+ + +N+ + T + L+L++ + +RA+++AL I
Sbjct: 3978 YGFEELSYMEFPSLDP------NNNYIYVKFATIKSHALLLYNYDNQTGDRAEFLALEIA 4031
Query: 1925 DGHLQLSYNLGSQPVVLRSTVPVNTNRWLRVVAHREQREGSLQVG--NEAPVTGSSPLGA 1982
+ L+ SYNLGS L + V+ + V+A R SL V +E G +
Sbjct: 4032 EERLRFSYNLGSGTYKLTTMKKVSDGHFHTVIARRAGMAASLTVDSCSENQEPGYCTVSN 4091
Query: 1983 TQLDTDGAL-------WLGGLPEL-PVGPALPKAYGTGFVGCLRDVVVGRHPLHLLEDAV 2034
+ D L +GG+ L P+ FVGC+ + V PL +
Sbjct: 4092 VAVSDDWTLDVQPNRVTVGGIRSLEPILQRRGHVESHDFVGCIMEFAVNGRPLEPSQALA 4151
Query: 2035 TKPELRPCP 2043
+ L CP
Sbjct: 4152 AQGILDQCP 4160
Score = 65.5 bits (158), Expect = 5e-10
Identities = 80/342 (23%), Positives = 115/342 (33%), Gaps = 65/342 (19%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEKVLGAPVPAF--------------- 1377
C PC HGGTC D+ C C G G CEK + P A
Sbjct: 4166 CTRSPCQHGGTCMDY--WSWQQCHCKEGLTGKYCEKSV-TPDTALSLEGKGRLDYHMSQN 4222
Query: 1378 EGRSFLAFPTLRA-----YHTLRLALEFRALEPQGLLLYNGNARGKDFLALALLDGRVQL 1432
E R +L +LR + L ++FR G+L++ + ++ + + +G+V
Sbjct: 4223 EKREYLLRQSLRGAMLEPFGVNSLEVKFRTRSENGVLIHIQES--SNYTTVKIKNGKVYF 4280
Query: 1433 RFDTGSGPAVLTSA--VPVEPGQWHRLELSRHWRRGTLSVDG-ETPVLGESPSGTDGLNL 1489
D G V + V V G WH + ++ LSVD + GL++
Sbjct: 4281 TSDAGIAGKVERNIPEVYVADGHWHTFLIGKNGTATVLSVDRIYNRDIIHPTQDFGGLDV 4340
Query: 1490 DTDLFVGGVPEDQAAVALERTFVGAGLRGCIRLLDVNNQRLELG----------IGPGAA 1539
T + +GG+P +QA R AG GCI + + L P
Sbjct: 4341 LT-ISLGGIPPNQA----HRDAQTAGFDGCIASMWYGGESLPFSGKHSLASISKTDPSVK 4395
Query: 1540 TRGSGVGECGDHPC---------------------LPNPCHGGAPCQNLEAGRFHCQCPP 1578
G C +PC +PC G C+ F C CP
Sbjct: 4396 IGCRGPNICASNPCWGDLLCINQWYAYRCVPPGDCASHPCQNGGSCEPGLHSGFTCSCPD 4455
Query: 1579 GRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQCECPLGRE 1620
G TC + C C C+ G C G E
Sbjct: 4456 SHTGRTC-EMVVACLGVLCPQGKVCKAGSPAGHVCVLSQGPE 4496
Score = 52.4 bits (124), Expect = 5e-06
Identities = 35/108 (32%), Positives = 40/108 (37%), Gaps = 24/108 (22%)
Query: 1541 RGSGVG-ECGDHP-CLPNPCHGGAPC---------------------QNLEAGRFHCQCP 1577
R SGV E DH C+ PC G C N F C+C
Sbjct: 3792 RQSGVKVESVDHDSCVHGPCQNGGSCLRRLAVSSVLKSRESLPVIIVANEPLQPFLCKCL 3851
Query: 1578 PGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQCECPLGREGTFCQ 1625
PG G C + C P+PCH C L GG C CP G G C+
Sbjct: 3852 PGYAGSWCEIDIDECLPSPCHSGGTCHNL-VGGFSCSCPDGFTGRACE 3898
Score = 48.5 bits (114), Expect = 7e-05
Identities = 21/42 (50%), Positives = 25/42 (59%), Gaps = 1/42 (2%)
Query: 1329 PPKPCDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEKVL 1370
PP C S PC +GG+C+ L GFTCSCP G CE V+
Sbjct: 4426 PPGDCASHPCQNGGSCEP-GLHSGFTCSCPDSHTGRTCEMVV 4466
Score = 43.5 bits (101), Expect = 0.002
Identities = 19/36 (52%), Positives = 22/36 (61%), Gaps = 2/36 (5%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEK 1368
C PC GGTC + L GGF+CSCP G G CE+
Sbjct: 3866 CLPSPCHSGGTCHN--LVGGFSCSCPDGFTGRACER 3899
Score = 34.7 bits (78), Expect = 0.98
Identities = 27/96 (28%), Positives = 32/96 (33%), Gaps = 19/96 (19%)
Query: 794 QCNPHGSY-GGTCDPATG--QCSCRPGVGGLRCDR---------CEPGFWNFRGIVTDGR 841
+C P + GGTC G CSC G G C+R C+ G +
Sbjct: 3865 ECLPSPCHSGGTCHNLVGGFSCSCPDGFTGRACERDINECLQSPCK------NGAICQNF 3918
Query: 842 SGCTPCSCDPQGAVRDDCEQMTGLCSCKPGVAGPKC 877
G C C G CE C C P G C
Sbjct: 3919 PGSFNCVCKT-GYTGKMCESSVNYCECNPCFNGGSC 3953
Score = 34.3 bits (77), Expect = 1.3
Identities = 25/85 (29%), Positives = 29/85 (34%), Gaps = 31/85 (36%)
Query: 865 LCSCKPGVAGPKCG--------------------------QCPDGRALGPAGCEADASAP 898
LC C PG AG C CPDG CE D +
Sbjct: 3847 LCKCLPGYAGSWCEIDIDECLPSPCHSGGTCHNLVGGFSCSCPDG--FTGRACERDIN-- 3902
Query: 899 ATCAEMRCEFGARCVEESGSAHCVC 923
C + C+ GA C GS +CVC
Sbjct: 3903 -ECLQSPCKNGAICQNFPGSFNCVC 3926
>gi|13325064 cadherin EGF LAG seven-pass G-type receptor 2 [Homo
sapiens]
Length = 2923
Score = 117 bits (292), Expect = 2e-25
Identities = 157/562 (27%), Positives = 216/562 (38%), Gaps = 107/562 (19%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEKVLGAPVPAFEGRSFLAFPTLRAYH 1392
C C +GGTC + L GGF C CP+G +V PA SF+ F LR
Sbjct: 1332 CTPGVCKNGGTCVN-LLVGGFKCDCPSGDFEKPYCQVTTRSFPA---HSFITFRGLRQRF 1387
Query: 1393 TLRLALEFRALEPQGLLLYNGNARGK-DFLALALLDGRVQLRFDTGSGPAVLTSAVP--V 1449
LAL F E GLLLYNG K DF+AL ++ +VQL F G ++ VP V
Sbjct: 1388 HFTLALSFATKERDGLLLYNGRFNEKHDFVALEVIQEQVQLTFSAGESTTTVSPFVPGGV 1447
Query: 1450 EPGQWHRLELSRH----------------WRRGTLSVDG-ET-------PVLGE---SPS 1482
GQWH ++L + + ++VDG +T VLG +
Sbjct: 1448 SDGQWHTVQLKYYNKPLLGQTGLPQGPSEQKVAVVTVDGCDTGVALRFGSVLGNYSCAAQ 1507
Query: 1483 GTDG-----LNLDTDLFVGGVPE-DQAAVALERTFVGAGLRGCIRLLDVNNQRLELGIGP 1536
GT G L+L L +GGVP+ ++ R FV GC+R L V+++ +++
Sbjct: 1508 GTQGGSKKSLDLTGPLLLGGVPDLPESFPVRMRQFV-----GCMRNLQVDSRHIDM--AD 1560
Query: 1537 GAATRGSGVG-ECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPN 1595
A G+ G + C N CH G C N + F C+CP G G +CA E + N
Sbjct: 1561 FIANNGTVPGCPAKKNVCDSNTCHNGGTCVN-QWDAFSCECPLGFGGKSCAQEMA----N 1615
Query: 1596 PCHGAAPCRVLPEGGAQCECPLGREGTFCQTASGQDGSGPFLADFNGFSHLELRGLHTFA 1655
P H V G P+ + + G L RG T
Sbjct: 1616 PQHFLGSSLVAWHG---LSLPISQPWYLSLMFRTRQADGVLLQAIT-------RGRSTIT 1665
Query: 1656 RDLGE-KMALEVVFLARGPSGLLLYNGQKTDGKGDFVSLALRDRRLEFRYDLGKGAAVIR 1714
L E + L V S L L G+ DG LAL G G A++
Sbjct: 1666 LQLREGHVMLSVEGTGLQASSLRLEPGRANDGDWHHAQLALGASG-------GPGHAIL- 1717
Query: 1715 SREPVTLGAWTRVSLERNGRKGALRVGDGPRVLGESPVPHTVLNLKEPLYVGGAPDFSKL 1774
+ +G L GPR+ G L+L + VGG P
Sbjct: 1718 -----------SFDYGQQRAEGNL----GPRLHG--------LHLSN-ITVGGIP----- 1748
Query: 1775 ARAAAVSSGFDGAIQLVSLG----GRQLLTPEHVLRQVDVTSFAGHPCTRASGHPCLNGA 1830
A V+ GF G +Q V + G L P H ++V P +PC +
Sbjct: 1749 GPAGGVARGFRGCLQGVRVSDTPEGVNSLDPSHG-ESINVEQGCSLP-DPCDSNPCPANS 1806
Query: 1831 SCVPREAAYVCLCPGGFSGPHC 1852
C +Y C C G+ G +C
Sbjct: 1807 YCSNDWDSYSCSCDPGYYGDNC 1828
Score = 111 bits (278), Expect = 6e-24
Identities = 97/317 (30%), Positives = 139/317 (43%), Gaps = 41/317 (12%)
Query: 1333 CDSQPCFHGGTC-QDWALGGGFTCSCPAGRGGAVCEKVLGAPVPAFEGRSFLAFP--TLR 1389
CDS C +GGTC W F+C CP G GG C + + P F G S +A+ +L
Sbjct: 1578 CDSNTCHNGGTCVNQW---DAFSCECPLGFGGKSCAQEMANP-QHFLGSSLVAWHGLSLP 1633
Query: 1390 AYHTLRLALEFRALEPQGLLLYNGNARGKDFLALALLDGRVQLRFDTGSGPAVLTSAVPV 1449
L+L FR + G+LL RG+ + L L +G V L + G + S++ +
Sbjct: 1634 ISQPWYLSLMFRTRQADGVLL-QAITRGRSTITLQLREGHVMLSVE---GTGLQASSLRL 1689
Query: 1450 EPGQ-----WHRLELSRHWRRGT----LSVD-GETPVLGESPSGTDGLNLDTDLFVGGVP 1499
EPG+ WH +L+ G LS D G+ G GL+L +++ VGG+P
Sbjct: 1690 EPGRANDGDWHHAQLALGASGGPGHAILSFDYGQQRAEGNLGPRLHGLHL-SNITVGGIP 1748
Query: 1500 EDQAAVALERTFVGAGLRGCIRLLDVNNQRLELGIGPGAATRGSGVG-ECG---DHPCLP 1555
VA G RGC++ + V++ G+ + G + E G PC
Sbjct: 1749 GPAGGVA-------RGFRGCLQGVRVSDT--PEGVNSLDPSHGESINVEQGCSLPDPCDS 1799
Query: 1556 NPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEG--GAQC 1613
NPC + C N + + C C PG G C + C NPC + C P G C
Sbjct: 1800 NPCPANSYCSN-DWDSYSCSCDPGYYGDNCT---NVCDLNPCEHQSVCTRKPSAPHGYTC 1855
Query: 1614 ECPLGREGTFCQTASGQ 1630
ECP G +C+T Q
Sbjct: 1856 ECPPNYLGPYCETRIDQ 1872
Score = 86.3 bits (212), Expect = 3e-16
Identities = 100/418 (23%), Positives = 152/418 (36%), Gaps = 72/418 (17%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTC--ADEKSPCQPNPCHGAAPCRVLPEGG 1610
C PC C++ E G + C C G G C + C P C C L GG
Sbjct: 1292 CYSRPCGPHGRCRSREGG-YTCLCRDGYTGEHCEVSARSGRCTPGVCKNGGTCVNLLVGG 1350
Query: 1611 AQCECPLGR-EGTFCQTASGQDGSGPFLADFNGFSHLELRGLHTFARDLGEKMALEVVFL 1669
+C+CP G E +CQ + F S + RGL L + F
Sbjct: 1351 FKCDCPSGDFEKPYCQVTT---------RSFPAHSFITFRGLRQRFH-----FTLALSFA 1396
Query: 1670 ARGPSGLLLYNGQKTDGKGDFVSLALRDRRLEFRYDLGKGAAVIRSREP--VTLGAWTRV 1727
+ GLLLYNG+ + K DFV+L + +++ + G+ + P V+ G W V
Sbjct: 1397 TKERDGLLLYNGRFNE-KHDFVALEVIQEQVQLTFSAGESTTTVSPFVPGGVSDGQWHTV 1455
Query: 1728 SLERNGRK--GALRVGDGPR----------------------VLGESPVP--------HT 1755
L+ + G + GP VLG
Sbjct: 1456 QLKYYNKPLLGQTGLPQGPSEQKVAVVTVDGCDTGVALRFGSVLGNYSCAAQGTQGGSKK 1515
Query: 1756 VLNLKEPLYVGGAPDFSKLARAAAVSSGFDGAIQLVSLGGRQLLTPEHVLRQVDVTSFAG 1815
L+L PL +GG PD + F G ++ + + R + + + V G
Sbjct: 1516 SLDLTGPLLLGGVPDLPESFPVRMRQ--FVGCMRNLQVDSRHIDMADFIANNGTVP---G 1570
Query: 1816 HPCTR--ASGHPCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVEKSAGDVDTLAFDGRT 1873
P + + C NG +CV + A+ C CP GF G C + + F G +
Sbjct: 1571 CPAKKNVCDSNTCHNGGTCVNQWDAFSCECPLGFGGKSCAQEMANPQ-------HFLGSS 1623
Query: 1874 FVEYLNAVTESEKALQSNHFELSLRTEATQGLVLWSGKATERADYVALAIVDGHLQLS 1931
V + S Q + L RT G++L + T + L + +GH+ LS
Sbjct: 1624 LVAWHGL---SLPISQPWYLSLMFRTRQADGVLLQA--ITRGRSTITLQLREGHVMLS 1676
Score = 68.9 bits (167), Expect = 5e-11
Identities = 69/287 (24%), Positives = 104/287 (36%), Gaps = 78/287 (27%)
Query: 1825 PCLNGASCVPREAAYVCLCPGGFSGPHCE------------------------------- 1853
PC C RE Y CLC G++G HCE
Sbjct: 1296 PCGPHGRCRSREGGYTCLCRDGYTGEHCEVSARSGRCTPGVCKNGGTCVNLLVGGFKCDC 1355
Query: 1854 -KGLVEKSAGDVDTLAFDGRTFVEYLNAVTESEKALQSNHFELSLR--TEATQGLVLWSG 1910
G EK V T +F +F+ + Q HF L+L T+ GL+L++G
Sbjct: 1356 PSGDFEKPYCQVTTRSFPAHSFITFRGL-------RQRFHFTLALSFATKERDGLLLYNG 1408
Query: 1911 KATERADYVALAIVDGHLQLSYNLGSQPVVLRSTVP--VNTNRWLRV------------- 1955
+ E+ D+VAL ++ +QL+++ G + VP V+ +W V
Sbjct: 1409 RFNEKHDFVALEVIQEQVQLTFSAGESTTTVSPFVPGGVSDGQWHTVQLKYYNKPLLGQT 1468
Query: 1956 ---VAHREQ----------------REGSLQVGNEAPVTGSSPLGATQLDTDGALWLGGL 1996
EQ R GS+ G+ LD G L LGG+
Sbjct: 1469 GLPQGPSEQKVAVVTVDGCDTGVALRFGSVLGNYSCAAQGTQGGSKKSLDLTGPLLLGGV 1528
Query: 1997 PELPVGPALPKAYGTGFVGCLRDVVVGRHPLHLLEDAVTKPELRPCP 2043
P+LP + P FVGC+R++ V + + + + CP
Sbjct: 1529 PDLP--ESFPVRM-RQFVGCMRNLQVDSRHIDMADFIANNGTVPGCP 1572
Score = 56.2 bits (134), Expect = 3e-07
Identities = 51/207 (24%), Positives = 75/207 (36%), Gaps = 42/207 (20%)
Query: 702 PCVCDFSCQSVPGSPVCGSDGVTYSTECELKKARCESQRGLY------VAAQGACRGPTF 755
P CD + P + C +D +YS C+ G Y V C +
Sbjct: 1794 PDPCDSN--PCPANSYCSNDWDSYSCSCD---------PGYYGDNCTNVCDLNPCEHQSV 1842
Query: 756 APLPPVAP----LHCAQTPYG-CCQDNITAARGVGLAGCPSA--CQCNPHGSYGGTCDPA 808
P AP C G C+ I G G P+ C C+ + C+
Sbjct: 1843 CTRKPSAPHGYTCECPPNYLGPYCETRIDQPCPRGWWGHPTCGPCNCDVSKGFDPDCNKT 1902
Query: 809 TGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDPQGAVRDDCEQMTGLCSC 868
+G+C C+ ++R G C C C P G++ C+ G C C
Sbjct: 1903 SGECHCKEN--------------HYR---PPGSPTCLLCDCYPTGSLSRVCDPEDGQCPC 1945
Query: 869 KPGVAGPKCGQCPDGRA-LGPAGCEAD 894
KPGV G +C +C + A + GCE +
Sbjct: 1946 KPGVIGRQCDRCDNPFAEVTTNGCEVN 1972
Score = 35.4 bits (80), Expect = 0.58
Identities = 16/44 (36%), Positives = 20/44 (45%), Gaps = 1/44 (2%)
Query: 1333 CDSQPCFHGGTC-QDWALGGGFTCSCPAGRGGAVCEKVLGAPVP 1375
CD PC H C + + G+TC CP G CE + P P
Sbjct: 1832 CDLNPCEHQSVCTRKPSAPHGYTCECPPNYLGPYCETRIDQPCP 1875
Score = 35.0 bits (79), Expect = 0.75
Identities = 67/278 (24%), Positives = 86/278 (30%), Gaps = 72/278 (25%)
Query: 553 CVCPSECVALAQPV---CGSDGHTYPSECMLHVHA--CTHQISLHVASAGPCETCGDAVC 607
C P C + P C +D +Y C + CT+ V PCE
Sbjct: 1791 CSLPDPCDSNPCPANSYCSNDWDSYSCSCDPGYYGDNCTN-----VCDLNPCEH------ 1839
Query: 608 AFGAVCSAGQCVCPRCEHPPPGPVCGSDGVTYGSACELREAACLQQTQIEEARAGPCEQA 667
Q VC R P G C G CE R + GPC
Sbjct: 1840 ---------QSVCTRKPSAPHGYTCECPPNYLGPYCETRIDQPCPRGWWGHPTCGPCN-- 1888
Query: 668 ECGSGGSGSGEDGDCEQELCRQRGGIWDEDSEDGPCVCDFSCQSVPGSPVC--------G 719
C G D DC + G C C + PGSP C G
Sbjct: 1889 -CDVS---KGFDPDCNKT--------------SGECHCKENHYRPPGSPTCLLCDCYPTG 1930
Query: 720 SDGVTYSTECELKKARCESQRGLYVAAQGACRGPTFAPLPPVAPLHCAQTPYGCCQDNIT 779
S S C+ + +C + G+ C P FA + + + Y C I
Sbjct: 1931 S----LSRVCDPEDGQCPCKPGVIGRQCDRCDNP-FAEV----TTNGCEVNYDSCPRAIE 1981
Query: 780 AARGVGLA----GCPSACQCNPHGSYGGT---CDPATG 810
A G+ G P+A C P GS+G CD G
Sbjct: 1982 A--GIWWPRTRFGLPAAAPC-PKGSFGTAVRHCDEHRG 2016
Score = 34.3 bits (77), Expect = 1.3
Identities = 17/41 (41%), Positives = 19/41 (46%), Gaps = 4/41 (9%)
Query: 1330 PKPCDSQPCFHGGTC-QDWALGGGFTCSCPAGRGGAVCEKV 1369
P PCDS PC C DW ++CSC G G C V
Sbjct: 1794 PDPCDSNPCPANSYCSNDW---DSYSCSCDPGYYGDNCTNV 1831
>gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo
sapiens]
Length = 3312
Score = 113 bits (283), Expect = 2e-24
Identities = 154/580 (26%), Positives = 207/580 (35%), Gaps = 137/580 (23%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRG--GAVCEKVLGAPVPAFEGRSFLAFPTLRA 1390
C C +GGTC D A GGF C CPAG G CE +F SF+ F LR
Sbjct: 1479 CVPGVCRNGGTCTD-APNGGFRCQCPAGGAFEGPRCE----VAARSFPPSSFVMFRGLRQ 1533
Query: 1391 YHTLRLALEFRALEPQGLLLYNGNARGK-DFLALALLDGRVQLRFDTGSGPAVLTSAVP- 1448
L L+L F ++ GLL YNG K DFLAL L+ G+V+L + TG V++ VP
Sbjct: 1534 RFHLTLSLSFATVQQSGLLFYNGRLNEKHDFLALELVAGQVRLTYSTGESNTVVSPTVPG 1593
Query: 1449 -VEPGQWHRLELSRHWRR-----------------GTLSVDG----------------ET 1474
+ GQWH + L R++ + LSVD
Sbjct: 1594 GLSDGQWHTVHL-RYYNKPRTDALGGAQGPSKDKVAVLSVDDCDVAVALQFGAEIGNYSC 1652
Query: 1475 PVLGESPSGTDGLNLDTDLFVGGVPE-DQAAVALERTFVGAGLRGCIRLLDVNNQRLELG 1533
G S L+L L +GGVP + + F+ GC+R L ++ +R+++
Sbjct: 1653 AAAGVQTSSKKSLDLTGPLLLGGVPNLPENFPVSHKDFI-----GCMRDLHIDGRRVDM- 1706
Query: 1534 IGPGAATRGSGVG-ECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPC 1592
A G+ G + H C PC C G F C CP G
Sbjct: 1707 -AAFVANNGTMAGCQAKLHFCDSGPCKNSGFCSE-RWGSFSCDCPVG------------- 1751
Query: 1593 QPNPCHGAAPCRVLPEGGAQCECPLGREGTFCQTASGQDGSGPFLADFNGFSHLELRGLH 1652
GG C+ + F RG
Sbjct: 1752 ---------------FGGKDCQLTMAHPHHF-------------------------RGNG 1771
Query: 1653 TFARDLGEKMALEV------VFLARGPSGLLLYNGQKTDGKGDFVSLALRDRRLEFRYDL 1706
T + + G MA+ V F R G+L+ Q G + L L
Sbjct: 1772 TLSWNFGSDMAVSVPWYLGLAFRTRATQGVLM---QVQAGPHSTLLCQLDRGLLSVTVTR 1828
Query: 1707 GKGAA--VIRSREPVTLGAWTRVSLERNGRKGALRVGDGPRVLGES----------PVPH 1754
G G A ++ + V+ G W + LE G R G VL S V
Sbjct: 1829 GSGRASHLLLDQVTVSDGRWHDLRLELQEEPGGRR---GHHVLMVSLDFSLFQDTMAVGS 1885
Query: 1755 TVLNLK-EPLYVGGAPDFSKLARAAAVSSGFDGAIQLVSLGGRQLLTPEHVLRQVDVTSF 1813
+ LK + L+VGG P S A G G IQ V LG +P + V +
Sbjct: 1886 ELQGLKVKQLHVGGLPPGS----AEEAPQGLVGCIQGVWLGSTPSGSPALLPPSHRVNAE 1941
Query: 1814 AGHPCTRA-SGHPCLNGASCVPREAAYVCLCPGGFSGPHC 1852
G T A + PC A C + C C G+ GP C
Sbjct: 1942 PGCVVTNACASGPCPPHADCRDLWQTFSCTCQPGYYGPGC 1981
Score = 97.4 bits (241), Expect = 1e-19
Identities = 130/531 (24%), Positives = 191/531 (35%), Gaps = 101/531 (19%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCA--DEKSPCQPNPCHGAAPCRVLPEGG 1610
C NPC G C E G + C C P G C E C P C C P GG
Sbjct: 1439 CYSNPCRNGGACARREGG-YTCVCRPRFTGEDCELDTEAGRCVPGVCRNGGTCTDAPNGG 1497
Query: 1611 AQCECPLGR--EGTFCQTASGQDGSGPFLADFNGFSHLELRGLHTFARDLGEKMALEVVF 1668
+C+CP G EG C+ A+ F S + RGL + L + F
Sbjct: 1498 FRCQCPAGGAFEGPRCEVAA---------RSFPPSSFVMFRGLRQRFH-----LTLSLSF 1543
Query: 1669 LARGPSGLLLYNGQKTDGKGDFVSLALRDRRLEFRYDLGKGAAVIRSREPVTL--GAWTR 1726
SGLL YNG+ + K DF++L L ++ Y G+ V+ P L G W
Sbjct: 1544 ATVQQSGLLFYNGRLNE-KHDFLALELVAGQVRLTYSTGESNTVVSPTVPGGLSDGQWHT 1602
Query: 1727 VSLE--RNGRKGALRVGDGP------------------------------RVLGESPVPH 1754
V L R AL GP G
Sbjct: 1603 VHLRYYNKPRTDALGGAQGPSKDKVAVLSVDDCDVAVALQFGAEIGNYSCAAAGVQTSSK 1662
Query: 1755 TVLNLKEPLYVGGAPDFSKLARAAAVSSGFDGAIQLVSLGGRQLLTPEHVLRQVDVTSFA 1814
L+L PL +GG P+ + F G ++ + + G R+VD+ +F
Sbjct: 1663 KSLDLTGPLLLGGVPNLPE--NFPVSHKDFIGCMRDLHIDG----------RRVDMAAFV 1710
Query: 1815 GHPCTRA---------SGHPCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVEKSAGDVD 1865
+ T A PC N C R ++ C CP GF G C+ +
Sbjct: 1711 ANNGTMAGCQAKLHFCDSGPCKNSGFCSERWGSFSCDCPVGFGGKDCQLTMAHPH----- 1765
Query: 1866 TLAFDGRTFVEYLNAVTESEKALQSNHFELSLRTEATQGLVLWSGKATERADYVALAIVD 1925
F G + + N ++ ++ + L+ RT ATQG VL +A + + +
Sbjct: 1766 --HFRGNGTLSW-NFGSDMAVSVPW-YLGLAFRTRATQG-VLMQVQAGPHSTLLC-QLDR 1819
Query: 1926 GHLQLSYNLGSQPV--VLRSTVPVNTNRWLRVVAHREQREGS------LQVGNEAPVTGS 1977
G L ++ GS +L V V+ RW + ++ G L V + +
Sbjct: 1820 GLLSVTVTRGSGRASHLLLDQVTVSDGRWHDLRLELQEEPGGRRGHHVLMVSLDFSLFQD 1879
Query: 1978 SPLGATQLD--TDGALWLGGLPELPVGPALPKAYGTGFVGCLRDVVVGRHP 2026
+ ++L L +GGLP P + G VGC++ V +G P
Sbjct: 1880 TMAVGSELQGLKVKQLHVGGLP-----PGSAEEAPQGLVGCIQGVWLGSTP 1925
Score = 97.1 bits (240), Expect = 2e-19
Identities = 101/321 (31%), Positives = 129/321 (40%), Gaps = 54/321 (16%)
Query: 1333 CDSQPCFHGGTCQD-WALGGGFTCSCPAGRGGAVCEKVLGAPVPAFEGRSFLAF---PTL 1388
CDS PC + G C + W G F+C CP G GG C+ + P F G L++ +
Sbjct: 1726 CDSGPCKNSGFCSERW---GSFSCDCPVGFGGKDCQLTMAHP-HHFRGNGTLSWNFGSDM 1781
Query: 1389 RAYHTLRLALEFRALEPQGLLLYNGNARGKDFLALALLDGRVQLRFDTGSGPA--VLTSA 1446
L L FR QG+L+ A L L G + + GSG A +L
Sbjct: 1782 AVSVPWYLGLAFRTRATQGVLM-QVQAGPHSTLLCQLDRGLLSVTVTRGSGRASHLLLDQ 1840
Query: 1447 VPVEPGQWH--RLELSRH--WRRG--------TLSVDGETPVLGESPSGTDGLNLDTDLF 1494
V V G+WH RLEL RRG S+ +T +G S GL + L
Sbjct: 1841 VTVSDGRWHDLRLELQEEPGGRRGHHVLMVSLDFSLFQDTMAVG---SELQGLKV-KQLH 1896
Query: 1495 VGGVPEDQAAVALERTFVGAGLRGCIRLLDVNNQRLELGIGPGAATR--------GSGVG 1546
VGG+P A A + GL GCI Q + LG P + + G
Sbjct: 1897 VGGLPPGSAEEAPQ------GLVGCI-------QGVWLGSTPSGSPALLPPSHRVNAEPG 1943
Query: 1547 ECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVL 1606
+ C PC A C++L F C C PG GP C D C NPC CR L
Sbjct: 1944 CVVTNACASGPCPPHADCRDLWQ-TFSCTCQPGYYGPGCVD---ACLLNPCQNQGSCRHL 1999
Query: 1607 PEG--GAQCECPLGREGTFCQ 1625
P G C+C G G C+
Sbjct: 2000 PGAPHGYTCDCVGGYFGHHCE 2020
Score = 58.5 bits (140), Expect = 6e-08
Identities = 37/137 (27%), Positives = 53/137 (38%), Gaps = 22/137 (16%)
Query: 747 QGACRGPTFAPLPPVAPLHCAQTPYGC-CQDNITAARGVGLAGCPSA--CQCNPHGSYGG 803
QG+CR AP C +G C+ + G G P+ C C+ H +
Sbjct: 1993 QGSCRHLPGAPHGYTCD--CVGGYFGHHCEHRMDQQCPRGWWGSPTCGPCNCDVHKGFDP 2050
Query: 804 TCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDPQGAVRDDCEQMT 863
C+ GQC C+ +++R G C PC C P G+ C +
Sbjct: 2051 NCNKTNGQCHCKE--------------FHYR---PRGSDSCLPCDCYPVGSTSRSCAPHS 2093
Query: 864 GLCSCKPGVAGPKCGQC 880
G C C+PG G +C C
Sbjct: 2094 GQCPCRPGALGRQCNSC 2110
Score = 55.5 bits (132), Expect = 5e-07
Identities = 40/134 (29%), Positives = 59/134 (44%), Gaps = 13/134 (9%)
Query: 702 PCVCDFSCQSVPGSP---VCGSDGVTYSTECELKKARCESQRGLYVAAQ-GACRGPTFAP 757
PC SC+ +PG+P C G + CE + + + RG + + G C
Sbjct: 1989 PCQNQGSCRHLPGAPHGYTCDCVGGYFGHHCEHRMDQ-QCPRGWWGSPTCGPCNCDVHKG 2047
Query: 758 LPPVAPLHCAQTPYGC-CQDNITAARGVGLAGCPSACQCNPHGSYGGTCDPATGQCSCRP 816
P +C +T C C++ RG + C C P GS +C P +GQC CRP
Sbjct: 2048 FDP----NCNKTNGQCHCKEFHYRPRG---SDSCLPCDCYPVGSTSRSCAPHSGQCPCRP 2100
Query: 817 GVGGLRCDRCEPGF 830
G G +C+ C+ F
Sbjct: 2101 GALGRQCNSCDSPF 2114
Score = 40.4 bits (93), Expect = 0.018
Identities = 34/108 (31%), Positives = 41/108 (37%), Gaps = 18/108 (16%)
Query: 755 FAPLPPVAPLHCAQTPYGCCQDNITAARGVGLAGCPSACQCNPHGSYGGTCDPATG--QC 812
F P+ P+A L C + P G D + C NP + GG C G C
Sbjct: 1410 FRPIQPIAGLRC-RCPPGFTGDFCETELDL--------CYSNPCRN-GGACARREGGYTC 1459
Query: 813 SCRPGVGGLRCD------RCEPGFWNFRGIVTDGRSGCTPCSCDPQGA 854
CRP G C+ RC PG G TD +G C C GA
Sbjct: 1460 VCRPRFTGEDCELDTEAGRCVPGVCRNGGTCTDAPNGGFRCQCPAGGA 1507
Score = 38.1 bits (87), Expect = 0.089
Identities = 48/200 (24%), Positives = 60/200 (30%), Gaps = 60/200 (30%)
Query: 737 ESQRGLYVAAQGACRGPTFAPLPPVAP-LHCAQTPYGCCQDNITAARGVGLAGCPSACQC 795
E+ +GL QG G T + P + P H GC N A+ CP C
Sbjct: 1907 EAPQGLVGCIQGVWLGSTPSGSPALLPPSHRVNAEPGCVVTNACAS-----GPCPPHADC 1961
Query: 796 NPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDPQGAV 855
T C+C+PG G C C C QG+
Sbjct: 1962 RDLWQ--------TFSCTCQPGYYGPGC-----------------VDACLLNPCQNQGS- 1995
Query: 856 RDDCEQMTG-----LCSCKPGVAGPKC-----GQCPDGRALGPAGCEADASAPATCAEMR 905
C + G C C G G C QCP G P TC
Sbjct: 1996 ---CRHLPGAPHGYTCDCVGGYFGHHCEHRMDQQCPRGWWGSP-----------TCGPCN 2041
Query: 906 CE----FGARCVEESGSAHC 921
C+ F C + +G HC
Sbjct: 2042 CDVHKGFDPNCNKTNGQCHC 2061
Score = 32.7 bits (73), Expect = 3.7
Identities = 27/86 (31%), Positives = 30/86 (34%), Gaps = 11/86 (12%)
Query: 847 CSCDPQGAVRDDCEQMTGLCSCKPGVAGPKCGQCPDG-------RALGPAGCEADASAPA 899
C C P G D CE LC P G C + G R G CE D A
Sbjct: 1421 CRCPP-GFTGDFCETELDLCYSNPCRNGGACARREGGYTCVCRPRFTG-EDCELDTEA-G 1477
Query: 900 TCAEMRCEFGARCVE-ESGSAHCVCP 924
C C G C + +G C CP
Sbjct: 1478 RCVPGVCRNGGTCTDAPNGGFRCQCP 1503
Score = 32.0 bits (71), Expect = 6.4
Identities = 53/192 (27%), Positives = 69/192 (35%), Gaps = 45/192 (23%)
Query: 166 PTPPDA-CRGMLCGFGAVCEPNAEGPGRASCV--CKKSPCPS-------VVAP---VCGS 212
P PP A CR + F C+P GPG CV C +PC + AP C
Sbjct: 1954 PCPPHADCRDLWQTFSCTCQPGYYGPG---CVDACLLNPCQNQGSCRHLPGAPHGYTCDC 2010
Query: 213 DASTYSNECELQRAQCSQQRRIRLLSRGPCG-----SRDPCSNVT-----CSFGSTCARS 262
+ + CE + Q + + GPC DP N T C R
Sbjct: 2011 VGGYFGHHCEHRMDQQCPRGWWGSPTCGPCNCDVHKGFDPNCNKTNGQCHCKEFHYRPRG 2070
Query: 263 ADGLTASCLCPATCRGAPEGTVCGSDGADYPGECQLLRRACARQENVFKKFDGPCDPCQG 322
+D SCL P C P G+ S A + G+C A RQ C+ C
Sbjct: 2071 SD----SCL-PCDC--YPVGSTSRS-CAPHSGQCPCRPGALGRQ----------CNSCDS 2112
Query: 323 ALPDPSRS-CRV 333
+ + S CRV
Sbjct: 2113 PFAEVTASGCRV 2124
>gi|148833508 notch1 preproprotein [Homo sapiens]
Length = 2555
Score = 112 bits (280), Expect = 4e-24
Identities = 203/902 (22%), Positives = 280/902 (31%), Gaps = 184/902 (20%)
Query: 159 THFTPVPPTPPDACRGMLCGFGAVCEPNAEGPGRASCV-------CKKS--PCPS---VV 206
TH P P C C G C P + +C+ C+++ CP
Sbjct: 209 THTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKN 268
Query: 207 APVCGSDASTYSNEC--ELQRAQCSQQRRIRLLSRGPCGSRDPCSNVTCSFGSTCARSAD 264
C +TY+ C E C++ L C + C N + C
Sbjct: 269 GGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWT 328
Query: 265 GLTAS-----CLCPATCRGAPEGTVCGSDGADYPGECQLLRRACARQENVFKKFDGPCDP 319
G S C A GA C A + EC R N D
Sbjct: 329 GEDCSENIDDCASAACFHGA----TCHDRVASFYCECPHGRTGLLCHLN---------DA 375
Query: 320 CQGALPDPSRSCRVNPRTRRPEMLLRPESCPA-RQAPVCGDDGVTYENDCVMGRSGAAR- 377
C + +C NP + +CP+ P C D ++C +G +
Sbjct: 376 CISNPCNEGSNCDTNPVNGKAIC-----TCPSGYTGPACSQD----VDECSLGANPCEHA 426
Query: 378 GLLLQKVRSGQCQ------------GRDQC-PEPCRFNAVCLSRRGRPRCSC-------- 416
G + + S +CQ ++C PC+ +A CL + G +C C
Sbjct: 427 GKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVH 486
Query: 417 DRVTCDGAYRPVCAQDGRTYDSDCWRQQAECRQQRAIPSKHQGP-CDQAPSPCLGVQCAF 475
V D C +GR D Q EC P+ G C C C
Sbjct: 487 CEVNTDECASSPCLHNGRCLDK-INEFQCEC------PTGFTGHLCQYDVDECASTPCKN 539
Query: 476 GATCAVKNGQAACECLQACSSLYDPV----CGSDGVTYGSACELEATACTLGREIQVARK 531
GA C C C + + + V C D YGS + AT L
Sbjct: 540 GAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCL--------- 590
Query: 532 GPCDRCGQCRFGALCEAETGRCVCPSECVALAQPVCGSDGHTYPSECMLHVHACTHQISL 591
C G CE C S C + Y C+ +I+L
Sbjct: 591 -----CRPGYTGHHCETNINEC---SSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINL 642
Query: 592 HVASAGPCE--TCGDAVCAFGAVCSAG-----------QCVCPRCEHPPPGPVCGSDGVT 638
++ PC+ TC D + + C G +C C + G C DG+
Sbjct: 643 DDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHN---GGTC-EDGIN 698
Query: 639 YGSACELREA----ACLQQTQIEEARAGPCEQAECGSGGSGSGEDGDCEQELCRQRGGIW 694
G C E CL +++ E + PC C S +G DC+ I
Sbjct: 699 -GFTCRCPEGYHDPTCL--SEVNECNSNPCVHGACRD--SLNGYKCDCDPGWSGTNCDIN 753
Query: 695 DEDSEDGPCVCDFSCQSVPGSPVCGSDGVTYSTECELKKARCESQRGLYVAAQGACRGPT 754
+ + E PCV +C+ + VC C+ C S L QG C
Sbjct: 754 NNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCL---NQGTC---- 806
Query: 755 FAPLPPVAPLHCAQTPYGCCQDNITAARGVGLAGC-PSAC----QCN------------P 797
+ VA C C A V LA C PS C +C P
Sbjct: 807 ---IDDVAGYKC-----NCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCP 858
Query: 798 HGSYGGTCDPATGQC---------SCRPGVGGLRC---------------DRCEPGFWNF 833
G G TC+ +C SC+ GG RC D C P +
Sbjct: 859 TGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHN 918
Query: 834 RGIVTDGRSGCTPCSCDPQGAVRDDCEQMTGLCSCKPGVAGPKCGQCPDGRA----LGPA 889
G TDG + C C P G CE+ C+ P G C C D G +
Sbjct: 919 GGSCTDGINTAF-CDCLP-GFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFS 976
Query: 890 GCEADASAPATCAEMRCEFGARCVEESGSAHCVCP--MLTCPEANATKVCGSDGVTYGNE 947
G + + P C E C G CV+ S C+CP + C S +G
Sbjct: 977 GIHCENNTP-DCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGT 1035
Query: 948 CQ 949
CQ
Sbjct: 1036 CQ 1037
Score = 105 bits (263), Expect = 3e-22
Identities = 186/883 (21%), Positives = 268/883 (30%), Gaps = 211/883 (23%)
Query: 169 PDACRGMLCGFGAVCEP-NAEGPGRASCVCK---KSP-CPSVVAPVCGSDASTYSNECEL 223
P+ C C C + G +C C P C + + C ++ C+L
Sbjct: 60 PNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDL 119
Query: 224 QRAQCSQQRRIRLLSRGPCGSRDPCSNVTCSFGSTCARSADGLTASCLCPATCRGAPEGT 283
+ R S C DPC++ C+ G C AS +C C + G
Sbjct: 120 LTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCL----PFEASYIC--HCPPSFHGP 173
Query: 284 VCGSDGADYPGECQLLRRACARQENVFKKFDGPCDPCQGALPDPSRSCRVNPRTRRPEML 343
C D EC C + G C G+ R+ P RP +
Sbjct: 174 TCRQD----VNECGQKPGLC--------RHGGTCHNEVGSYRCVCRATHTGPNCERPYVP 221
Query: 344 LRPESCPARQAPVCGDDG-VTYENDCVMGRSGAARGLLLQKVRSGQCQGR-DQCP-EPCR 400
P C + C G VT+E C+ G +G C+ D CP C+
Sbjct: 222 CSPSPC--QNGGTCRPTGDVTHECACLPGFTGQ------------NCEENIDDCPGNNCK 267
Query: 401 FNAVCLSRRGRPRCSCDRVTCDGAYRPVCAQDGRTYDSDCWRQQAECRQQRAIPSKHQG- 459
C+ C C G Y C +D +C C+ + H G
Sbjct: 268 NGGACVDGVNTYNCRCP-PEWTGQY---CTED----VDECQLMPNACQNGGTCHNTHGGY 319
Query: 460 -----------PCDQAPSPCLGVQCAFGATCAVKNGQAACECLQACSSLY---------- 498
C + C C GATC + CEC + L
Sbjct: 320 NCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISN 379
Query: 499 ----------DPVCGS------DGVTYGSACELEATACTLGREIQVARKGPCDRCGQC-- 540
+PV G G T G AC + C+LG PC+ G+C
Sbjct: 380 PCNEGSNCDTNPVNGKAICTCPSGYT-GPACSQDVDECSLG-------ANPCEHAGKCIN 431
Query: 541 ------------RFGALCEAETGRCV---CPSECVALAQPVCGSDGHTYPSECMLHVHAC 585
G CE + CV C ++ L Q + CM
Sbjct: 432 TLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQI------GEFQCICMPGYEGV 485
Query: 586 THQISLHVASAGPC---ETCGDAVCAFGAVCSAG-----------QCVCPRCEHPPPGPV 631
+++ ++ PC C D + F C G +C C++ G
Sbjct: 486 HCEVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKN---GAK 542
Query: 632 CGSDGVTYGSACELREAACLQQTQIEEARAGPCEQAECGSGGS------GSGEDG-DCEQ 684
C TY C + I+E PC C G + G G CE
Sbjct: 543 CLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHCET 602
Query: 685 ELCRQRGGIWDEDSEDGPCVCDFSCQSVPGSPVCGSDGVTYSTECELKKARCES---QRG 741
+ + PC +CQ + +C T CE+ C S G
Sbjct: 603 NI---------NECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSG 653
Query: 742 LYV----AAQGACRGPTFAPLPPVAPLHCAQTPY---GCCQDNITAARGVGLAGCPSACQ 794
+ + AC + + CA P G C+D I C+
Sbjct: 654 TCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGING----------FTCR 703
Query: 795 CNPHGSYGGTCDPATGQC--------SCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTP 846
C P G + TC +C +CR + G +CD C+PG+ + + P
Sbjct: 704 C-PEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCD-CDPGWSGTNCDINNNECESNP 761
Query: 847 CSCDPQGAVRDDCEQMTG--LCSCKPGVAGPKC----GQCPDGRALGPAGCEADAS---- 896
C C+ MT +C+C+ G +GP C +C L C D +
Sbjct: 762 C------VNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKC 815
Query: 897 -------------APATCAEMRCEFGARC--VEESGSAHCVCP 924
A CA C G C E+ S CVCP
Sbjct: 816 NCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCP 858
Score = 94.4 bits (233), Expect = 1e-18
Identities = 180/868 (20%), Positives = 253/868 (29%), Gaps = 222/868 (25%)
Query: 170 DACRGMLCGFGAVCEPNAEGPGRASCVCKKSPCPSVVAPVCGSDASTYSNECELQRAQCS 229
DAC C G+ C+ N G+A C C P C D +EC L C
Sbjct: 374 DACISNPCNEGSNCDTNPVN-GKAICTCPSG----YTGPACSQDV----DECSLGANPCE 424
Query: 230 QQRR-IRLLSRGPCGSRDPCSNVTCSFG-STCARSADGLTASCL-----CPATCRGAPEG 282
+ I L C + C + C + A+CL C EG
Sbjct: 425 HAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEG 484
Query: 283 TVCGSDGADYPGECQLLRRACARQENVFKKFDGPCDPCQGALPDPSRSCRVNPRTRRPEM 342
C + + L C + N F+ C+ C+ +
Sbjct: 485 VHCEVNTDECASSPCLHNGRCLDKINEFQ--------CECPTGFTGHLCQYD-------- 528
Query: 343 LLRPESCPARQAPVCGDDGVTYENDCVMGRSGAARGLLLQKVRSGQCQ-GRDQC-PEPCR 400
+ S P + C D TY C G +G C+ D+C P+PC
Sbjct: 529 VDECASTPCKNGAKCLDGPNTYTCVCTEGYTGT------------HCEVDIDECDPDPCH 576
Query: 401 FNA--------VCLSRRGRPRCSCDRVTCDGAYRPVCAQDGRTYDSD------CWRQQAE 446
+ + CL R G C+ + + +P C G D D C +
Sbjct: 577 YGSCKDGVATFTCLCRPGYTGHHCETNINECSSQP-CRHGGTCQDRDNAYLCFCLKGTTG 635
Query: 447 CRQQRAIPSKHQGPCDQAP-------------------------SPCLGVQCAFGATCAV 481
+ + PCD C G C G TC
Sbjct: 636 PNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCED 695
Query: 482 KNGQAACECLQ----------------------AC-SSLYDPVCGSDGVTYGSACEL--- 515
C C + AC SL C D G+ C++
Sbjct: 696 GINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNN 755
Query: 516 --EATACTLGREIQVARKGPCDRCGQCRFGALCEAETGRCVCPSECVALAQPVCGSDGHT 573
E+ C G + G C + G C+ C + C L Q C D
Sbjct: 756 ECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECAS-NPC--LNQGTCIDDVAG 812
Query: 574 YPSECMLHVHACTHQISLHVASAGPCETCGDA-----VCAFGAVCSAG-----------Q 617
Y C+L T ++ L + PC G+ +F VC G +
Sbjct: 813 YKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINE 872
Query: 618 CVCPRCEHPPPGPVCGSDGVTYGSACELREAACLQQTQIEEARAGPCEQAECGSGGSGSG 677
CV C H G C + Y C+ + +T I++ R PC GS
Sbjct: 873 CVLSPCRH---GASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNG-------GSC 922
Query: 678 EDG------DCEQELCRQRGGIWDEDSED---GPCVCDFSCQSVPGSPVCGSDGVTYSTE 728
DG DC L RG +ED + PC +C S C
Sbjct: 923 TDGINTAFCDC---LPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIH 979
Query: 729 CELKKARCESQRGLYVAAQGACRGPTFAPLPPVAPLHCAQTPYGCCQDNITAARGVGLAG 788
CE C + +C G C D I +
Sbjct: 980 CENNTPDC---------TESSCFNG------------------GTCVDGINSF------- 1005
Query: 789 CPSACQCNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCS 848
C C P G G C +C +P + G C+ G ++R C+
Sbjct: 1006 ---TCLCPP-GFTGSYCQHDVNECDSQPCLHG---GTCQDGCGSYR------------CT 1046
Query: 849 CDPQGAVRDDCEQMTGLCSCKPGVAGPKCGQ--------CPDGRA-----LGPAGCEADA 895
C PQG +C+ + C P G KC Q CP G + CE A
Sbjct: 1047 C-PQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAA 1105
Query: 896 SAPATCAEMRCEFGARCVEESGSAHCVC 923
C+ G CV+ + HC C
Sbjct: 1106 QRQGVDVARLCQHGGLCVDAGNTHHCRC 1133
Score = 91.3 bits (225), Expect = 9e-18
Identities = 182/834 (21%), Positives = 246/834 (29%), Gaps = 219/834 (26%)
Query: 170 DACRGMLCGFGAVCEPNA--------EGPGRASCV-----CKKSPC------PSVVAPVC 210
D C G C G CE EG +C+ C +PC S+ C
Sbjct: 680 DECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKC 739
Query: 211 GSDASTYSNECELQRAQCSQQRRIRLLSRGPCGSRDPCSNVTCSFGSTCARSADGLTAS- 269
D C++ +C PC + C ++T + TC G
Sbjct: 740 DCDPGWSGTNCDINNNECESN---------PCVNGGTCKDMTSGYVCTCREGFSGPNCQT 790
Query: 270 ---------CLCPATCRGAPEGTVCGSDGADYPGECQLLRRACA----------RQENVF 310
CL TC G C C+++ CA RQ +
Sbjct: 791 NINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDY 850
Query: 311 KKFDGPCDP-CQGALPDPSRSCRVNPRTRRPEMLLRPESCPARQAPVCGDDGVTYENDCV 369
+ F C QG ++C V+ E +L P R C + Y C
Sbjct: 851 ESFSCVCPTGWQG------QTCEVDIN----ECVLSP----CRHGASCQNTHGGYRCHCQ 896
Query: 370 MGRSGAARGLLLQKVRSGQCQGRDQCPEPCRFNAVCLSRRGRPRCSCDRVTCDGAYRPVC 429
G SG R+ + D P PC C C C G C
Sbjct: 897 AGYSG----------RNCETDIDDCRPNPCHNGGSCTDGINTAFCDC----LPGFRGTFC 942
Query: 430 AQDGRTYDSDCWRQQAECRQ-----QRAIPSKHQG-PCDQAPSPCLGVQCAFGATCAVKN 483
+D SD R A C P+ G C+ C C G TC
Sbjct: 943 EEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGI 1002
Query: 484 GQAACECLQACSSLYDPVCGSDGVTYGSACELEATACTLGREIQVARKGPCDRCGQCRFG 543
C C G T GS C+ + C PC G C+ G
Sbjct: 1003 NSFTCLC-------------PPGFT-GSYCQHDVNECD---------SQPCLHGGTCQDG 1039
Query: 544 ALCEAETGRCVCPSECVALAQPVCGSDGHTYPSECMLHVHACTHQISLHVASAGPCETCG 603
+ RC CP G+T P+ C VH C + T
Sbjct: 1040 C----GSYRCTCPQ-------------GYTGPN-CQNLVHWCDSSPCKNGGKCWQTHTQY 1081
Query: 604 DAVCAFG---------------AVCSAGQCVCPRCEHPPPGPVCGSDGVTYGSACELREA 648
C G A G V C+H G +C G T+ C+
Sbjct: 1082 RCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQH---GGLCVDAGNTHHCRCQAGYT 1138
Query: 649 ACLQQTQIEEARAGPCEQ-AECGSGGSG------SGEDG-DCEQELCRQRGGIWDEDSED 700
+ ++E PC+ A C G +G G +C +E+ ++
Sbjct: 1139 GSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEI---------DECLS 1189
Query: 701 GPCVCDFSCQSVPGSPVCGSDGVTYSTECELKKARCESQRGLYVAAQGACRGPTFAPLPP 760
PC +C +P + C T CE+ C PP
Sbjct: 1190 HPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCN---------------------PP 1228
Query: 761 VAPLHCAQTPYGCCQDNITAARGVGLAGCPSACQCNPHGSYGGTCDPATGQCSCRPGVGG 820
V P+ +++P C +N T VG +C C P G G C+ +C P
Sbjct: 1229 VDPV--SRSPK--CFNNGTCVDQVG----GYSCTCPP-GFVGERCEGDVNECLSNP---- 1275
Query: 821 LRCDRCEPGFWNFRGIVTDGRSGCTPCSCDPQGAVRDDCEQMTGLCSCKPGVAGPKCG-- 878
CD G N V D C G CE + C KP G C
Sbjct: 1276 --CDA--RGTQNCVQRVNDFHCECRA------GHTGRRCESVINGCKGKPCKNGGTCAVA 1325
Query: 879 ---------QCPDGRALGPAGCEADASAPATCAEMRCEFGARCVEESGSAHCVC 923
+CP G A CE DA TC +RC G C+ S C+C
Sbjct: 1326 SNTARGFICKCPAG--FEGATCENDAR---TCGSLRCLNGGTCISGPRSPTCLC 1374
Score = 77.4 bits (189), Expect = 1e-13
Identities = 177/824 (21%), Positives = 247/824 (29%), Gaps = 166/824 (20%)
Query: 170 DACRGMLCGFGAVCEPNAEGPGRASCVCKKS----------------PC------PSVVA 207
D C C GA C +GP +CVC + PC V
Sbjct: 530 DECASTPCKNGAKC---LDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVAT 586
Query: 208 PVCGSDASTYSNECELQRAQCSQQRRIRLLSRGPCGSRDPCSNVTCSFGST---CARSAD 264
C + CE +CS Q G C RD C G+T C + D
Sbjct: 587 FTCLCRPGYTGHHCETNINECSSQP---CRHGGTCQDRDNAYLCFCLKGTTGPNCEINLD 643
Query: 265 GLTASCLCPATCRGAPEGTVCGSDGADYPGECQLLRRACARQENVFKKFDGPCD---PCQ 321
+S TC +G C + C + CA PC C+
Sbjct: 644 DCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINIDECA---------GNPCHNGGTCE 694
Query: 322 GALPDPSRSCRVNPRTRRPEMLLRPESCPARQAP--VCGDDGVTYENDCVMGRSGAARGL 379
+ +CR P L C + C D Y+ DC G SG +
Sbjct: 695 DGIN--GFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDI 752
Query: 380 LLQKVRSGQCQGRDQCPEPCRFNAVCLSRRGRPRCSCDRVTCDGAYRPVCAQDGRTYDSD 439
+ S C C + VC R G +C + A P C G D D
Sbjct: 753 NNNECESNPCVNGGTCKDMTS-GYVCTCREGFSGPNCQTNINECASNP-CLNQGTCID-D 809
Query: 440 CWRQQAECRQQRAIPSKHQGPCDQAPSPCLGVQCAFGATCAVKNGQAACECLQACSSLYD 499
+ C + C+ +PC C G C + C+ C + +
Sbjct: 810 VAGYKCNC-----LLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCV--CPTGWQ 862
Query: 500 PVCGSDGVTYGSACELEATACTL-----GREIQVARKGPCDRCGQCRFGALCEAETGRCV 554
G CE++ C L G Q G C G CE + C
Sbjct: 863 ----------GQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCR 912
Query: 555 CPSECVALAQPVCGSDGHTYPSECMLHVHACTHQISLHVASAGPCET---CGDAVCAFGA 611
P+ C C +T +C+ + ++ ++ PC C D V ++
Sbjct: 913 -PNPCHNGGS--CTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTC 969
Query: 612 VCSAGQCVCPRCEHPPPGPVCGSDGVTYGSACE--LREAACLQQTQIEEARAGPCEQAEC 669
C AG CE+ P C G C + CL C
Sbjct: 970 TCPAGFSGI-HCENNTPD--CTESSCFNGGTCVDGINSFTCL-----------------C 1009
Query: 670 GSGGSGS---GEDGDCEQELCRQRGGIWDEDSEDGPCVCDF-----SCQSVP---GSPVC 718
G +GS + +C+ + C GG + C C +CQ++ S C
Sbjct: 1010 PPGFTGSYCQHDVNECDSQPCLH-GGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPC 1068
Query: 719 GSDGVTYSTECELKKARCESQRGLYVAAQGACRGPTFAPLPPVAPLHCAQTPYGCCQDNI 778
+ G + T + RCE G L+C C +
Sbjct: 1069 KNGGKCWQTHTQY---RCECPSGW-------------------TGLYCDVPSVSC---EV 1103
Query: 779 TAAR-GVGLAGCPSACQCNPHGSYGGTCDPA--TGQCSCRPGVGGLRC----DRCEPGFW 831
A R GV +A CQ +GG C A T C C+ G G C D C P
Sbjct: 1104 AAQRQGVDVA---RLCQ------HGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPC 1154
Query: 832 NFRGIVTDGRSGCTPCSCDPQGAVRDDCEQMTGLCSCKPGVAGPKCGQCPDG------RA 885
TD G + C C G +C + C P G C P+ R
Sbjct: 1155 QNGATCTDYLGGYS-CKC-VAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRG 1212
Query: 886 LGPAGCEA---DASAPA--TCAEMRCEFGARCVEESGSAHCVCP 924
CE D + P +C CV++ G C CP
Sbjct: 1213 TQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCP 1256
Score = 69.3 bits (168), Expect = 4e-11
Identities = 36/100 (36%), Positives = 44/100 (44%), Gaps = 4/100 (4%)
Query: 1550 DHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLP-E 1608
D+ CL NPC G C L + C+CPPG G +C + PC NPC C LP E
Sbjct: 103 DNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSC-QQADPCASNPCANGGQC--LPFE 159
Query: 1609 GGAQCECPLGREGTFCQTASGQDGSGPFLADFNGFSHLEL 1648
C CP G C+ + G P L G H E+
Sbjct: 160 ASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEV 199
Score = 69.3 bits (168), Expect = 4e-11
Identities = 172/839 (20%), Positives = 244/839 (29%), Gaps = 190/839 (22%)
Query: 172 CRGMLCGFGAVCEPNAEGPGRASCV--CKKSPCPSVVAPVCGSDASTYSNECELQRAQCS 229
C+ M G+ C GP + + C +PC + C D + Y C L +
Sbjct: 768 CKDMTSGYVCTCREGFSGPNCQTNINECASNPCLN--QGTCIDDVAGYKCNCLLPYTGAT 825
Query: 230 QQRRIRLLSRGPCGSRDPCSNVTCSFGSTCARSADGLTASCLCPATCRG----------- 278
+ + PC+ C G C +S D + SC+CP +G
Sbjct: 826 CEVVLA-----------PCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECV 874
Query: 279 ---APEGTVCGSDGADYPGECQLLRRACARQENVFKKFDGPC---DPCQGALPDPSRSCR 332
G C + Y CQ + ++ PC C + C
Sbjct: 875 LSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCL 934
Query: 333 VNPR-TRRPEMLLRPESCPARQAPVCGDDGVTYENDCVMGRSGAARGLLLQKVRSGQCQG 391
R T E + S P R C D +Y C G SG C
Sbjct: 935 PGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFN 994
Query: 392 RDQCPEPCR-FNAVCLSRRGRPRCSCDRVTCDGAYRPVCAQDGRTYDSDCWRQQAECRQQ 450
C + F +C C D CD C G D C + C
Sbjct: 995 GGTCVDGINSFTCLCPPGFTGSYCQHDVNECDS---QPCLHGGTCQDG-CGSYRCTC--- 1047
Query: 451 RAIPSKHQGP-CDQAPSPCLGVQCAFGATCAVKNGQAACECLQACSSLYDPVCGSDGVTY 509
P + GP C C C G C + Q CEC + LY
Sbjct: 1048 ---PQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLY----------- 1093
Query: 510 GSACELEATACTLGREIQVARKGPCDRCGQCRFGALC--EAETGRCVCPS--------EC 559
C++ + +C E+ R+G D C+ G LC T C C + +
Sbjct: 1094 ---CDVPSVSC----EVAAQRQG-VDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDL 1145
Query: 560 VALAQPVCGSDGHT-------YPSECMLHVHACTHQISLHVASAGPCETCGDAVCAFGAV 612
V P +G T Y +C+ H + + PC+ G + +
Sbjct: 1146 VDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCL----DL 1201
Query: 613 CSAGQCVCPR------CE------HPPPGPV-----CGSDGVT------YGSACELREAA 649
+ +C CPR CE +PP PV C ++G Y C
Sbjct: 1202 PNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVG 1261
Query: 650 CLQQTQIEEARAGPCE--------------QAECGSGGSG---SGEDGDCEQELCRQRG- 691
+ + E + PC+ EC +G +G C+ + C+ G
Sbjct: 1262 ERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGT 1321
Query: 692 -GIWDEDSEDGPCVCDFSCQSVPGSPVCGSDGVTYSTECELKKARCESQRGLYVAAQGAC 750
+ + C C G +G T CE C S R L G C
Sbjct: 1322 CAVASNTARGFICKCP-----------AGFEGAT----CENDARTCGSLRCL---NGGTC 1363
Query: 751 ----RGPTFAPLPPVAPLHCAQTPYGCCQDNITAARGVGLAGCPSACQCNPHGSYGGTCD 806
R PT L P C C L G P Q GTC+
Sbjct: 1364 ISGPRSPTCLCLGPFTGPECQFPASSPC-----------LGGNPCYNQ--------GTCE 1404
Query: 807 PATG----QCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDPQGAVRDDCEQM 862
P + +C C GL C + F G P + + CE
Sbjct: 1405 PTSESPFYRCLCPAKFNGLLCHILDYSFGGGAG------------RDIPPPLIEEACE-- 1450
Query: 863 TGLCSCKPGVAGPKCGQCPDGRALGPAGCEADASAPATCAEMRCEFGARCVEESGSAHC 921
L C+ C + A G G D S C +C + HC
Sbjct: 1451 --LPECQEDAGNKVCSLQCNNHACGWDG--GDCSLNFNDPWKNCTQSLQCWKYFSDGHC 1505
Score = 67.4 bits (163), Expect = 1e-10
Identities = 126/554 (22%), Positives = 172/554 (31%), Gaps = 154/554 (27%)
Query: 427 PVCAQDGRTYDSDCWRQQAECRQQRAIPSKHQGPCDQAPSPCLGVQCAFGATCAV--KNG 484
P C+Q G T + + A + GP Q P+PCL C TC V + G
Sbjct: 22 PRCSQPGETCLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRG 81
Query: 485 QA--ACECLQA-----CSSLYDPVCGSDGVTYGSACELEATA-----CTLG------REI 526
A AC C C + D C ++ G C+L C G ++
Sbjct: 82 VADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQA 141
Query: 527 QVARKGPCDRCGQCRFGALCEAETGRCVCPSECVALAQPVCGSDGHTYPSECMLHVHACT 586
PC GQC L + C CP + P C D +EC C
Sbjct: 142 DPCASNPCANGGQC----LPFEASYICHCPP---SFHGPTCRQD----VNECGQKPGLCR 190
Query: 587 HQISLHVASAGPCETCGDAVCAFGAVCSAGQCVCPRCEHP----PPGPVCGSDGVTYGSA 642
H TC + V ++ VC A P CE P P P C + G +
Sbjct: 191 HG-----------GTCHNEVGSYRCVCRATH-TGPNCERPYVPCSPSP-CQNGGTCRPTG 237
Query: 643 CELREAACLQQTQIEEARAGPCEQAECGSGGSGSGED-GDCEQELCRQRGGIWDEDSEDG 701
E ACL G G E+ DC C+ G D
Sbjct: 238 DVTHECACLP-----------------GFTGQNCEENIDDCPGNNCKNGGACVDG----- 275
Query: 702 PCVCDFSCQSVPG--SPVCGSDGVTYSTECELKKARCESQRGLYVAAQGACRGPTFAPLP 759
V ++C+ P C D EC+L C++ G C
Sbjct: 276 --VNTYNCRCPPEWTGQYCTED----VDECQLMPNACQNG--------GTC--------- 312
Query: 760 PVAPLHCAQTPYGC-CQDNITAAR-GVGLAGCPSACQCNPHGSYGGTCDP--ATGQCSCR 815
H Y C C + T + C SA C +G TC A+ C C
Sbjct: 313 -----HNTHGGYNCVCVNGWTGEDCSENIDDCASAA-C----FHGATCHDRVASFYCECP 362
Query: 816 PGVGGLRC---DRCEPGFWNFRGIVTDGRSGCTPCSCDPQGAVRDDCEQMTGLCSCKPGV 872
G GL C D C +++ + + C +P +C+C G
Sbjct: 363 HGRTGLLCHLNDAC----------ISNPCNEGSNCDTNPVNG--------KAICTCPSGY 404
Query: 873 AGPKCGQCPDGRALGPAGCEADASAPAT-----------------------CAEMRCEFG 909
GP C Q D +LG CE T C C+
Sbjct: 405 TGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQND 464
Query: 910 ARCVEESGSAHCVC 923
A C+++ G C+C
Sbjct: 465 ATCLDQIGEFQCIC 478
Score = 65.1 bits (157), Expect = 7e-10
Identities = 32/85 (37%), Positives = 41/85 (48%), Gaps = 6/85 (7%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEG--G 1610
C+ +PC GA CQN G + C C G G C + C+PNPCH C +G
Sbjct: 873 CVLSPCRHGASCQNTHGG-YRCHCQAGYSGRNCETDIDDCRPNPCHNGGSC---TDGINT 928
Query: 1611 AQCECPLGREGTFCQTASGQDGSGP 1635
A C+C G GTFC+ + S P
Sbjct: 929 AFCDCLPGFRGTFCEEDINECASDP 953
Score = 64.3 bits (155), Expect = 1e-09
Identities = 35/84 (41%), Positives = 43/84 (51%), Gaps = 5/84 (5%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPC-HGAAPCRVLPEGGA 1611
C NPCH G C++ G F C+CP G PTC E + C NPC HGA CR G
Sbjct: 682 CAGNPCHNGGTCEDGING-FTCRCPEGYHDPTCLSEVNECNSNPCVHGA--CRD-SLNGY 737
Query: 1612 QCECPLGREGTFCQTASGQDGSGP 1635
+C+C G GT C + + S P
Sbjct: 738 KCDCDPGWSGTNCDINNNECESNP 761
Score = 64.3 bits (155), Expect = 1e-09
Identities = 44/147 (29%), Positives = 62/147 (42%), Gaps = 11/147 (7%)
Query: 1479 ESPSGTDGLNLDTDLFVGGVPEDQAAVALERTFVGAGLRGCIRLLDVNNQRLELGIGPGA 1538
E PSG GL D V + V + R GL C+ + ++ R + G
Sbjct: 1084 ECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGL--CVDAGNTHHCRCQAGY---- 1137
Query: 1539 ATRGSGVGECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCH 1598
GS + D C P+PC GA C + G + C+C G G C++E C +PC
Sbjct: 1138 --TGSYCEDLVDE-CSPSPCQNGATCTDYLGG-YSCKCVAGYHGVNCSEEIDECLSHPCQ 1193
Query: 1599 GAAPCRVLPEGGAQCECPLGREGTFCQ 1625
C LP +C CP G +G C+
Sbjct: 1194 NGGTCLDLP-NTYKCSCPRGTQGVHCE 1219
Score = 62.0 bits (149), Expect = 6e-09
Identities = 104/456 (22%), Positives = 139/456 (30%), Gaps = 122/456 (26%)
Query: 593 VASAGP-CETCGDAVCAFGAVCSAGQ----CVC------PRCEHPPP--GPVCGSDGVT- 638
+A+ GP C G+ C G C A CVC PRC+ P P C + G
Sbjct: 17 LAARGPRCSQPGET-CLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCH 75
Query: 639 ---------YGSACELREAACLQQTQIEEA-------RAGPCE-------QAECGSGGSG 675
Y +C L + L T ++ A G C+ + C G SG
Sbjct: 76 VVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSG 135
Query: 676 SGEDGDCEQELCRQRGGIWDEDSEDGPCVCDFSCQSVPGSPVCGSDGVTYSTECELKKAR 735
C+Q + PC C S +C + C
Sbjct: 136 KS----CQQA----------DPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNE 181
Query: 736 CESQRGLYVAAQGACRGPTFAPLPPVAPLHCA---QTPYGCCQDNITAARGVGLAGCPSA 792
C + GL G C + H + PY C PS
Sbjct: 182 CGQKPGL-CRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCS--------------PSP 226
Query: 793 CQCNPHGSYGGTCDPA---TGQCSCRPGVGGLRC----DRCEPGFWNFRGIVTDGRSGCT 845
CQ GGTC P T +C+C PG G C D C G DG +
Sbjct: 227 CQ------NGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYN 280
Query: 846 PCSCDPQGAVR------DDCEQMTGLC----SCKPGVAGPKCGQCPDGRALGPAGCEADA 895
C C P+ + D+C+ M C +C G C C +G D
Sbjct: 281 -CRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNC-VCVNGWTGEDCSENID- 337
Query: 896 SAPATCAEMRCEFGARCVEESGSAHCVCPM----LTCPEANATKVCGSDGVTYGNECQLK 951
CA C GA C + S +C CP L C + C S+ G+ C
Sbjct: 338 ----DCASAACFHGATCHDRVASFYCECPHGRTGLLC---HLNDACISNPCNEGSNCDTN 390
Query: 952 TI---------------ACRQGLQISIQSLGPCQEA 972
+ AC Q + PC+ A
Sbjct: 391 PVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHA 426
Score = 61.6 bits (148), Expect = 8e-09
Identities = 29/76 (38%), Positives = 38/76 (50%), Gaps = 2/76 (2%)
Query: 1552 PCLPNPCHGGAPC-QNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGG 1610
PC P+PC G C Q+ + F C CP G G TC + + C +PC A C+ GG
Sbjct: 832 PCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQ-NTHGG 890
Query: 1611 AQCECPLGREGTFCQT 1626
+C C G G C+T
Sbjct: 891 YRCHCQAGYSGRNCET 906
Score = 58.9 bits (141), Expect = 5e-08
Identities = 29/81 (35%), Positives = 34/81 (41%), Gaps = 4/81 (4%)
Query: 1545 VGECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCR 1604
V ECG P L C G C N E G + C C GP C PC P+PC CR
Sbjct: 179 VNECGQKPGL---CRHGGTCHN-EVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCR 234
Query: 1605 VLPEGGAQCECPLGREGTFCQ 1625
+ +C C G G C+
Sbjct: 235 PTGDVTHECACLPGFTGQNCE 255
Score = 58.2 bits (139), Expect = 8e-08
Identities = 31/82 (37%), Positives = 37/82 (45%), Gaps = 2/82 (2%)
Query: 1556 NPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQCEC 1615
NPC C N G F CQC G GP C + + C NPC A C + G QC C
Sbjct: 421 NPCEHAGKCINT-LGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATC-LDQIGEFQCIC 478
Query: 1616 PLGREGTFCQTASGQDGSGPFL 1637
G EG C+ + + S P L
Sbjct: 479 MPGYEGVHCEVNTDECASSPCL 500
Score = 57.4 bits (137), Expect = 1e-07
Identities = 31/84 (36%), Positives = 37/84 (44%), Gaps = 7/84 (8%)
Query: 1545 VGECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCR 1604
V EC PCL HGG CQ+ G + C CP G GP C + C +PC C
Sbjct: 1022 VNECDSQPCL----HGGT-CQD-GCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKC- 1074
Query: 1605 VLPEGGAQCECPLGREGTFCQTAS 1628
+CECP G G +C S
Sbjct: 1075 WQTHTQYRCECPSGWTGLYCDVPS 1098
Score = 56.2 bits (134), Expect = 3e-07
Identities = 29/86 (33%), Positives = 40/86 (46%), Gaps = 4/86 (4%)
Query: 1553 CLPNPCHGGAPCQ-NLEAGRFHCQCPPGRVGPTCADEKSPCQ--PNPCHGAAPCRVLPEG 1609
C+ NPC+ G+ C N G+ C CP G GP C+ + C NPC A C + G
Sbjct: 376 CISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKC-INTLG 434
Query: 1610 GAQCECPLGREGTFCQTASGQDGSGP 1635
+C+C G G C+ + S P
Sbjct: 435 SFECQCLQGYTGPRCEIDVNECVSNP 460
Score = 54.7 bits (130), Expect = 9e-07
Identities = 29/95 (30%), Positives = 37/95 (38%), Gaps = 8/95 (8%)
Query: 1543 SGVGECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAP 1602
S V EC +PC+ C + C C PG G C + C+ NPC
Sbjct: 715 SEVNECNSNPCVHGACRDSL-------NGYKCDCDPGWSGTNCDINNNECESNPCVNGGT 767
Query: 1603 CRVLPEGGAQCECPLGREGTFCQTASGQDGSGPFL 1637
C+ + G C C G G CQT + S P L
Sbjct: 768 CKDMTSGYV-CTCREGFSGPNCQTNINECASNPCL 801
Score = 54.7 bits (130), Expect = 9e-07
Identities = 26/73 (35%), Positives = 33/73 (45%), Gaps = 2/73 (2%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQ 1612
C PNPCH G C + F C C PG G C ++ + C +PC A C +
Sbjct: 911 CRPNPCHNGGSCTDGINTAF-CDCLPGFRGTFCEEDINECASDPCRNGANCTDCVD-SYT 968
Query: 1613 CECPLGREGTFCQ 1625
C CP G G C+
Sbjct: 969 CTCPAGFSGIHCE 981
Score = 53.1 bits (126), Expect = 3e-06
Identities = 29/85 (34%), Positives = 35/85 (41%), Gaps = 5/85 (5%)
Query: 1553 CLPNPC--HGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPE-- 1608
CL NPC G C FHC+C G G C + C+ PC C V
Sbjct: 1271 CLSNPCDARGTQNCVQ-RVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTA 1329
Query: 1609 GGAQCECPLGREGTFCQTASGQDGS 1633
G C+CP G EG C+ + GS
Sbjct: 1330 RGFICKCPAGFEGATCENDARTCGS 1354
Score = 52.8 bits (125), Expect = 3e-06
Identities = 29/83 (34%), Positives = 35/83 (42%), Gaps = 2/83 (2%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQ 1612
C+ NPC A C + + G F C C PG G C C +PC C + Q
Sbjct: 456 CVSNPCQNDATCLD-QIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRC-LDKINEFQ 513
Query: 1613 CECPLGREGTFCQTASGQDGSGP 1635
CECP G G CQ + S P
Sbjct: 514 CECPTGFTGHLCQYDVDECASTP 536
Score = 51.6 bits (122), Expect = 8e-06
Identities = 23/52 (44%), Positives = 28/52 (53%), Gaps = 2/52 (3%)
Query: 1319 PGRRPPAPQQPPKPCDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEKVL 1370
PG Q CDSQPC HGGTCQD G + C+CP G G C+ ++
Sbjct: 1011 PGFTGSYCQHDVNECDSQPCLHGGTCQDGC--GSYRCTCPQGYTGPNCQNLV 1060
Score = 51.2 bits (121), Expect = 1e-05
Identities = 24/79 (30%), Positives = 36/79 (45%), Gaps = 2/79 (2%)
Query: 1547 ECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVL 1606
+ ++ C NPC G C+++ +G + C C G GP C + C NPC C +
Sbjct: 751 DINNNECESNPCVNGGTCKDMTSG-YVCTCREGFSGPNCQTNINECASNPCLNQGTC-ID 808
Query: 1607 PEGGAQCECPLGREGTFCQ 1625
G +C C L G C+
Sbjct: 809 DVAGYKCNCLLPYTGATCE 827
Score = 51.2 bits (121), Expect = 1e-05
Identities = 24/71 (33%), Positives = 36/71 (50%), Gaps = 4/71 (5%)
Query: 1812 SFAGHPCTRASGHPCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVEKSAGDVDTLAFDG 1871
+F + PC NGA+C +Y C CP GFSG HCE + + ++ F+G
Sbjct: 940 TFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCT----ESSCFNG 995
Query: 1872 RTFVEYLNAVT 1882
T V+ +N+ T
Sbjct: 996 GTCVDGINSFT 1006
Score = 50.8 bits (120), Expect = 1e-05
Identities = 29/82 (35%), Positives = 34/82 (41%), Gaps = 9/82 (10%)
Query: 1545 VGECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPC- 1603
V EC +PN C G C N G ++C C G G C++ C C A C
Sbjct: 296 VDEC---QLMPNACQNGGTCHNTHGG-YNCVCVNGWTGEDCSENIDDCASAACFHGATCH 351
Query: 1604 -RVLPEGGAQCECPLGREGTFC 1624
RV CECP GR G C
Sbjct: 352 DRV---ASFYCECPHGRTGLLC 370
Score = 50.1 bits (118), Expect = 2e-05
Identities = 25/74 (33%), Positives = 32/74 (43%), Gaps = 2/74 (2%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPE-GGA 1611
C NPC C + AG + C C G TC +PC P+PC CR +
Sbjct: 795 CASNPCLNQGTCIDDVAG-YKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESF 853
Query: 1612 QCECPLGREGTFCQ 1625
C CP G +G C+
Sbjct: 854 SCVCPTGWQGQTCE 867
Score = 49.7 bits (117), Expect = 3e-05
Identities = 29/96 (30%), Positives = 44/96 (45%), Gaps = 14/96 (14%)
Query: 1777 AAAVSSGFDGAIQLVSLGGRQLLTPEHVLRQVDVTS-----------FAGHPCTRA---S 1822
A + + GF G + L L L P D+ + ++G C +A +
Sbjct: 86 ACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCA 145
Query: 1823 GHPCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVE 1858
+PC NG C+P EA+Y+C CP F GP C + + E
Sbjct: 146 SNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNE 181
Score = 49.3 bits (116), Expect = 4e-05
Identities = 32/98 (32%), Positives = 38/98 (38%), Gaps = 11/98 (11%)
Query: 1532 LGIGPGAATRGSGVGECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSP 1591
L + P A RG + G+ C G C+ G C C VGP C D +P
Sbjct: 11 LALLPALAARGPRCSQPGE------TCLNGGKCEAAN-GTEACVCGGAFVGPRCQDP-NP 62
Query: 1592 CQPNPCHGAAPCRVLPEGGA---QCECPLGREGTFCQT 1626
C PC A C V+ G C C LG G C T
Sbjct: 63 CLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLT 100
Score = 48.9 bits (115), Expect = 5e-05
Identities = 23/73 (31%), Positives = 27/73 (36%), Gaps = 1/73 (1%)
Query: 1552 PCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGA 1611
PC P+PC G C+ C C PG G C + C N C C V
Sbjct: 221 PCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGAC-VDGVNTY 279
Query: 1612 QCECPLGREGTFC 1624
C CP G +C
Sbjct: 280 NCRCPPEWTGQYC 292
Score = 48.9 bits (115), Expect = 5e-05
Identities = 25/85 (29%), Positives = 32/85 (37%), Gaps = 7/85 (8%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEG--G 1610
C +PC G ++ + C C PG G C C NPCH C +G G
Sbjct: 645 CASSPCDSGTCLDKIDG--YECACEPGYTGSMCNINIDECAGNPCHNGGTCE---DGING 699
Query: 1611 AQCECPLGREGTFCQTASGQDGSGP 1635
C CP G C + + S P
Sbjct: 700 FTCRCPEGYHDPTCLSEVNECNSNP 724
Score = 47.8 bits (112), Expect = 1e-04
Identities = 24/73 (32%), Positives = 30/73 (41%), Gaps = 2/73 (2%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQ 1612
C + C G C + F C CPPG G C + + C PC C+ G +
Sbjct: 987 CTESSCFNGGTCVD-GINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQD-GCGSYR 1044
Query: 1613 CECPLGREGTFCQ 1625
C CP G G CQ
Sbjct: 1045 CTCPQGYTGPNCQ 1057
Score = 46.6 bits (109), Expect = 2e-04
Identities = 26/79 (32%), Positives = 30/79 (37%), Gaps = 7/79 (8%)
Query: 1547 ECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVL 1606
EC PCL H G + F C+CP G G C + C PC A C
Sbjct: 493 ECASSPCL----HNGRCLDKIN--EFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDG 546
Query: 1607 PEGGAQCECPLGREGTFCQ 1625
P C C G GT C+
Sbjct: 547 P-NTYTCVCTEGYTGTHCE 564
Score = 46.6 bits (109), Expect = 2e-04
Identities = 20/52 (38%), Positives = 26/52 (50%), Gaps = 4/52 (7%)
Query: 1811 TSFAGHPCT----RASGHPCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVE 1858
T F GH C + PC NGA C+ Y C+C G++G HCE + E
Sbjct: 518 TGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDE 569
Score = 46.6 bits (109), Expect = 2e-04
Identities = 26/85 (30%), Positives = 34/85 (40%), Gaps = 2/85 (2%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQ 1612
C +PC GA C + + C CP G G C + C + C C V
Sbjct: 949 CASDPCRNGANCTDC-VDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTC-VDGINSFT 1006
Query: 1613 CECPLGREGTFCQTASGQDGSGPFL 1637
C CP G G++CQ + S P L
Sbjct: 1007 CLCPPGFTGSYCQHDVNECDSQPCL 1031
Score = 46.6 bits (109), Expect = 2e-04
Identities = 24/71 (33%), Positives = 31/71 (43%), Gaps = 4/71 (5%)
Query: 1558 CHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPC--HGAAPCRVLPEGGAQCEC 1615
C C + + G + C CPPG VG C + + C NPC G C V CEC
Sbjct: 1238 CFNNGTCVD-QVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNC-VQRVNDFHCEC 1295
Query: 1616 PLGREGTFCQT 1626
G G C++
Sbjct: 1296 RAGHTGRRCES 1306
Score = 46.2 bits (108), Expect = 3e-04
Identities = 20/58 (34%), Positives = 31/58 (53%), Gaps = 4/58 (6%)
Query: 1813 FAGHPC----TRASGHPCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVEKSAGDVDT 1866
+ GH C S PC +G +C R+ AY+C C G +GP+CE L + ++ D+
Sbjct: 595 YTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDS 652
Score = 45.8 bits (107), Expect = 4e-04
Identities = 24/74 (32%), Positives = 30/74 (40%), Gaps = 4/74 (5%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQ--PNPCHGAAPCRVLPEGG 1610
C N C G C + ++C+CPP G C ++ CQ PN C C GG
Sbjct: 261 CPGNNCKNGGACVD-GVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCH-NTHGG 318
Query: 1611 AQCECPLGREGTFC 1624
C C G G C
Sbjct: 319 YNCVCVNGWTGEDC 332
Score = 45.4 bits (106), Expect = 6e-04
Identities = 36/120 (30%), Positives = 46/120 (38%), Gaps = 14/120 (11%)
Query: 1535 GPGAATRGSGVGECGDH------PCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADE 1588
GP T G G H C P+PCH G+ C++ A F C C PG G C
Sbjct: 546 GPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGS-CKDGVA-TFTCLCRPGYTGHHCETN 603
Query: 1589 KSPCQPNPCHGAAPCRVLPEGGAQCECPLGREGTFCQ-----TASGQDGSGPFLADFNGF 1643
+ C PC C+ + C C G G C+ AS SG L +G+
Sbjct: 604 INECSSQPCRHGGTCQD-RDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGY 662
Score = 44.7 bits (104), Expect = 0.001
Identities = 16/35 (45%), Positives = 23/35 (65%)
Query: 1824 HPCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVE 1858
+PC+NG +C + YVC C GFSGP+C+ + E
Sbjct: 760 NPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINE 794
Score = 44.3 bits (103), Expect = 0.001
Identities = 27/85 (31%), Positives = 36/85 (42%), Gaps = 7/85 (8%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGA- 1611
C PC GA C + + C C G G C + C P+PCH + C+ +G A
Sbjct: 532 CASTPCKNGAKCLD-GPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGS-CK---DGVAT 586
Query: 1612 -QCECPLGREGTFCQTASGQDGSGP 1635
C C G G C+T + S P
Sbjct: 587 FTCLCRPGYTGHHCETNINECSSQP 611
Score = 44.3 bits (103), Expect = 0.001
Identities = 36/119 (30%), Positives = 44/119 (36%), Gaps = 17/119 (14%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQP--NPCHGAAPC-----RV 1605
CL +PC G C +L + C CP G G C C P +P + C V
Sbjct: 1187 CLSHPCQNGGTCLDLP-NTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCV 1245
Query: 1606 LPEGGAQCECPLGREGTFCQTASGQDGSGP--------FLADFNGFSHLELRGLHTFAR 1656
GG C CP G G C+ + S P + N F H E R HT R
Sbjct: 1246 DQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDF-HCECRAGHTGRR 1303
Score = 43.5 bits (101), Expect = 0.002
Identities = 15/42 (35%), Positives = 23/42 (54%)
Query: 1812 SFAGHPCTRASGHPCLNGASCVPREAAYVCLCPGGFSGPHCE 1853
S+ H PCL+G +C +Y C CP G++GP+C+
Sbjct: 1016 SYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQ 1057
Score = 41.2 bits (95), Expect = 0.010
Identities = 17/41 (41%), Positives = 25/41 (60%), Gaps = 3/41 (7%)
Query: 1818 CTRASGHPCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVE 1858
CT +S C NG +CV ++ CLCP GF+G +C+ + E
Sbjct: 987 CTESS---CFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNE 1024
Score = 41.2 bits (95), Expect = 0.010
Identities = 15/30 (50%), Positives = 17/30 (56%)
Query: 1824 HPCLNGASCVPREAAYVCLCPGGFSGPHCE 1853
HPC NG +C+ Y C CP G G HCE
Sbjct: 1190 HPCQNGGTCLDLPNTYKCSCPRGTQGVHCE 1219
Score = 40.4 bits (93), Expect = 0.018
Identities = 17/34 (50%), Positives = 18/34 (52%), Gaps = 2/34 (5%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVC 1366
C S CFHG TC D F C CP GR G +C
Sbjct: 339 CASAACFHGATCHDRV--ASFYCECPHGRTGLLC 370
Score = 40.4 bits (93), Expect = 0.018
Identities = 18/35 (51%), Positives = 19/35 (54%), Gaps = 2/35 (5%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCE 1367
C SQPC HGGTCQD + C C G G CE
Sbjct: 607 CSSQPCRHGGTCQD--RDNAYLCFCLKGTTGPNCE 639
Score = 40.4 bits (93), Expect = 0.018
Identities = 19/50 (38%), Positives = 25/50 (50%), Gaps = 2/50 (4%)
Query: 1318 VPGRRPPAPQQPPKPCDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCE 1367
+PG R ++ C S PC +G C D +TC+CPAG G CE
Sbjct: 934 LPGFRGTFCEEDINECASDPCRNGANCTDCV--DSYTCTCPAGFSGIHCE 981
Score = 40.4 bits (93), Expect = 0.018
Identities = 18/36 (50%), Positives = 21/36 (58%), Gaps = 1/36 (2%)
Query: 1333 CDSQPCFHGGTCQDWA-LGGGFTCSCPAGRGGAVCE 1367
C +PC +GGTC + GF C CPAG GA CE
Sbjct: 1311 CKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCE 1346
Score = 40.0 bits (92), Expect = 0.023
Identities = 15/35 (42%), Positives = 22/35 (62%), Gaps = 2/35 (5%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCE 1367
C+S PC +GGTC+D + G+ C+C G G C+
Sbjct: 757 CESNPCVNGGTCKD--MTSGYVCTCREGFSGPNCQ 789
Score = 39.3 bits (90), Expect = 0.040
Identities = 19/56 (33%), Positives = 25/56 (44%), Gaps = 1/56 (1%)
Query: 1798 LLTPEHVLRQVDVTSFAGHPCTRASGHPCLNGASCVPREAAYVCLCPGGFSGPHCE 1853
LL P L + + G C++ G CLNG C C+C G F GP C+
Sbjct: 4 LLAPLLCLALLPALAARGPRCSQP-GETCLNGGKCEAANGTEACVCGGAFVGPRCQ 58
Score = 39.3 bits (90), Expect = 0.040
Identities = 16/34 (47%), Positives = 18/34 (52%), Gaps = 2/34 (5%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVC 1366
C PC +GGTC+D GFTC CP G C
Sbjct: 682 CAGNPCHNGGTCEDGI--NGFTCRCPEGYHDPTC 713
Score = 39.3 bits (90), Expect = 0.040
Identities = 18/35 (51%), Positives = 20/35 (57%), Gaps = 2/35 (5%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCE 1367
C S PC +GGTC D L + CSCP G G CE
Sbjct: 1187 CLSHPCQNGGTCLD--LPNTYKCSCPRGTQGVHCE 1219
Score = 38.5 bits (88), Expect = 0.068
Identities = 16/35 (45%), Positives = 19/35 (54%), Gaps = 2/35 (5%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCE 1367
C CF+GGTC D FTC CP G G+ C+
Sbjct: 987 CTESSCFNGGTCVDGI--NSFTCLCPPGFTGSYCQ 1019
Score = 38.1 bits (87), Expect = 0.089
Identities = 22/84 (26%), Positives = 31/84 (36%), Gaps = 10/84 (11%)
Query: 1551 HPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQ-PNPCHGAAPCRVLPEG 1609
H C +PC G C ++ C+CP G G C C+ G R+ G
Sbjct: 1061 HWCDSSPCKNGGKCWQTHT-QYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHG 1119
Query: 1610 GA--------QCECPLGREGTFCQ 1625
G C C G G++C+
Sbjct: 1120 GLCVDAGNTHHCRCQAGYTGSYCE 1143
Score = 38.1 bits (87), Expect = 0.089
Identities = 15/35 (42%), Positives = 19/35 (54%), Gaps = 2/35 (5%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCE 1367
CDS PC +GG C W + C CP+G G C+
Sbjct: 1063 CDSSPCKNGGKC--WQTHTQYRCECPSGWTGLYCD 1095
Score = 37.7 bits (86), Expect = 0.12
Identities = 20/51 (39%), Positives = 24/51 (47%), Gaps = 4/51 (7%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEKVLG--APVPAFEGRS 1381
C PC HG +CQ+ GG+ C C AG G CE + P P G S
Sbjct: 873 CVLSPCRHGASCQN--THGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGS 921
Score = 37.7 bits (86), Expect = 0.12
Identities = 15/36 (41%), Positives = 20/36 (55%), Gaps = 2/36 (5%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEK 1368
C PC +G TC D+ GG++C C AG G C +
Sbjct: 1149 CSPSPCQNGATCTDYL--GGYSCKCVAGYHGVNCSE 1182
Score = 37.7 bits (86), Expect = 0.12
Identities = 18/40 (45%), Positives = 22/40 (55%), Gaps = 3/40 (7%)
Query: 1329 PPKPCDSQP-CFHGGTCQDWALGGGFTCSCPAGRGGAVCE 1367
P P P CF+ GTC D GG++C+CP G G CE
Sbjct: 1228 PVDPVSRSPKCFNNGTCVDQV--GGYSCTCPPGFVGERCE 1265
Score = 37.4 bits (85), Expect = 0.15
Identities = 21/49 (42%), Positives = 24/49 (48%), Gaps = 4/49 (8%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEKVLG--APVPAFEG 1379
C S PC + GTC D G+ C+C GA CE VL AP P G
Sbjct: 795 CASNPCLNQGTCIDDV--AGYKCNCLLPYTGATCEVVLAPCAPSPCRNG 841
Score = 37.4 bits (85), Expect = 0.15
Identities = 15/36 (41%), Positives = 18/36 (50%)
Query: 1332 PCDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCE 1367
PC PC +GG C+ F+C CP G G CE
Sbjct: 832 PCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCE 867
Score = 37.4 bits (85), Expect = 0.15
Identities = 13/28 (46%), Positives = 18/28 (64%)
Query: 1826 CLNGASCVPREAAYVCLCPGGFSGPHCE 1853
CLNG +C+ + CLC G F+GP C+
Sbjct: 1357 CLNGGTCISGPRSPTCLCLGPFTGPECQ 1384
Score = 37.0 bits (84), Expect = 0.20
Identities = 31/92 (33%), Positives = 37/92 (40%), Gaps = 11/92 (11%)
Query: 1279 LPSSAVT-PRAPHPSHTSQPVAKTTAAPTTRRPPTTAPSRVPGRRPPAPQ-QPPKPCDSQ 1336
LP+ A PR P T K AA T + V G P+ Q P PC S
Sbjct: 14 LPALAARGPRCSQPGETCLNGGKCEAANGTE-------ACVCGGAFVGPRCQDPNPCLST 66
Query: 1337 PCFHGGTCQ--DWALGGGFTCSCPAGRGGAVC 1366
PC + GTC D + CSC G G +C
Sbjct: 67 PCKNAGTCHVVDRRGVADYACSCALGFSGPLC 98
Score = 36.6 bits (83), Expect = 0.26
Identities = 12/30 (40%), Positives = 19/30 (63%)
Query: 1824 HPCLNGASCVPREAAYVCLCPGGFSGPHCE 1853
+PC N A+C+ + + C+C G+ G HCE
Sbjct: 459 NPCQNDATCLDQIGEFQCICMPGYEGVHCE 488
Score = 36.6 bits (83), Expect = 0.26
Identities = 14/29 (48%), Positives = 17/29 (58%)
Query: 1825 PCLNGASCVPREAAYVCLCPGGFSGPHCE 1853
PC +GASC Y C C G+SG +CE
Sbjct: 877 PCRHGASCQNTHGGYRCHCQAGYSGRNCE 905
Score = 36.6 bits (83), Expect = 0.26
Identities = 13/28 (46%), Positives = 15/28 (53%)
Query: 1826 CLNGASCVPREAAYVCLCPGGFSGPHCE 1853
C N +CV + Y C CP GF G CE
Sbjct: 1238 CFNNGTCVDQVGGYSCTCPPGFVGERCE 1265
Score = 36.6 bits (83), Expect = 0.26
Identities = 30/112 (26%), Positives = 37/112 (33%), Gaps = 22/112 (19%)
Query: 1553 CLPNPCHGGAPCQ--NLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEG- 1609
C PC G C + A F C+CP G G TC ++ C C C P
Sbjct: 1311 CKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSP 1370
Query: 1610 ---------GAQCECP-----LGREGTFCQTASGQDGSGPFL-----ADFNG 1642
G +C+ P LG + Q PF A FNG
Sbjct: 1371 TCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNG 1422
Score = 36.2 bits (82), Expect = 0.34
Identities = 15/41 (36%), Positives = 23/41 (56%), Gaps = 2/41 (4%)
Query: 1824 HPCLNGASCV--PREAAYVCLCPGGFSGPHCEKGLVEKSAG 1862
+PC G++C P +C CP G++GP C + + E S G
Sbjct: 379 NPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLG 419
Score = 35.8 bits (81), Expect = 0.44
Identities = 15/41 (36%), Positives = 22/41 (53%), Gaps = 1/41 (2%)
Query: 1817 PCTRASGHPCLNGASCVPR-EAAYVCLCPGGFSGPHCEKGL 1856
P S PC NG +C P + + C C GF+G +CE+ +
Sbjct: 218 PYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENI 258
Score = 35.8 bits (81), Expect = 0.44
Identities = 15/35 (42%), Positives = 17/35 (48%), Gaps = 2/35 (5%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCE 1367
C S PC H G C D F C CP G G +C+
Sbjct: 494 CASSPCLHNGRCLDKI--NEFQCECPTGFTGHLCQ 526
Score = 35.8 bits (81), Expect = 0.44
Identities = 14/34 (41%), Positives = 17/34 (50%), Gaps = 3/34 (8%)
Query: 1823 GHPCLNGASCVPRE---AAYVCLCPGGFSGPHCE 1853
G PC NG +C ++C CP GF G CE
Sbjct: 1313 GKPCKNGGTCAVASNTARGFICKCPAGFEGATCE 1346
Score = 35.0 bits (79), Expect = 0.75
Identities = 12/29 (41%), Positives = 16/29 (55%)
Query: 1825 PCLNGASCVPREAAYVCLCPGGFSGPHCE 1853
PC NG C Y C CP G++G +C+
Sbjct: 1067 PCKNGGKCWQTHTQYRCECPSGWTGLYCD 1095
Score = 35.0 bits (79), Expect = 0.75
Identities = 14/37 (37%), Positives = 19/37 (51%)
Query: 1822 SGHPCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVE 1858
S PC NGA+C Y C C G+ G +C + + E
Sbjct: 1150 SPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDE 1186
Score = 35.0 bits (79), Expect = 0.75
Identities = 17/41 (41%), Positives = 21/41 (51%), Gaps = 4/41 (9%)
Query: 1814 AGHPCTRASGHPCLNGASCVPREAA--YVCLCPGGFSGPHC 1852
A PC G+PC N +C P + Y CLCP F+G C
Sbjct: 1387 ASSPCL--GGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLC 1425
Score = 34.7 bits (78), Expect = 0.98
Identities = 13/36 (36%), Positives = 17/36 (47%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEK 1368
C S PC G C + G C+CP+G G C +
Sbjct: 376 CISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQ 411
Score = 34.7 bits (78), Expect = 0.98
Identities = 12/31 (38%), Positives = 17/31 (54%)
Query: 1822 SGHPCLNGASCVPREAAYVCLCPGGFSGPHC 1852
+G+PC NG +C + C CP G+ P C
Sbjct: 683 AGNPCHNGGTCEDGINGFTCRCPEGYHDPTC 713
Score = 34.3 bits (77), Expect = 1.3
Identities = 22/65 (33%), Positives = 28/65 (43%), Gaps = 6/65 (9%)
Query: 1319 PGRRPPAPQQPPKPCDSQP--CFHGGTCQDWALGGGFTCSCPAGRGGAVCEK--VLGAPV 1374
P P +Q C +P C HGGTC + G + C C A G CE+ V +P
Sbjct: 168 PSFHGPTCRQDVNECGQKPGLCRHGGTCHNEV--GSYRCVCRATHTGPNCERPYVPCSPS 225
Query: 1375 PAFEG 1379
P G
Sbjct: 226 PCQNG 230
Score = 34.3 bits (77), Expect = 1.3
Identities = 16/37 (43%), Positives = 21/37 (56%), Gaps = 1/37 (2%)
Query: 1825 PCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVEKSA 1861
PC G SC A + CLC G++G HCE + E S+
Sbjct: 574 PCHYG-SCKDGVATFTCLCRPGYTGHHCETNINECSS 609
Score = 33.9 bits (76), Expect = 1.7
Identities = 16/50 (32%), Positives = 23/50 (46%), Gaps = 4/50 (8%)
Query: 1813 FAGHPCTR----ASGHPCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVE 1858
F G C G+ C NG +CV Y C CP ++G +C + + E
Sbjct: 249 FTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDE 298
Score = 33.5 bits (75), Expect = 2.2
Identities = 18/47 (38%), Positives = 24/47 (51%), Gaps = 5/47 (10%)
Query: 1324 PAPQQPPKPCDSQPCFHGGTCQDWALGGGFT--CSCPAGRGGAVCEK 1368
P ++P PC PC +GGTC+ G T C+C G G CE+
Sbjct: 213 PNCERPYVPCSPSPCQNGGTCRP---TGDVTHECACLPGFTGQNCEE 256
Score = 33.1 bits (74), Expect = 2.9
Identities = 14/41 (34%), Positives = 18/41 (43%), Gaps = 2/41 (4%)
Query: 1328 QPPKPCDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEK 1368
Q PC S PC +GG C + + C CP G C +
Sbjct: 139 QQADPCASNPCANGGQCLPFE--ASYICHCPPSFHGPTCRQ 177
Score = 32.7 bits (73), Expect = 3.7
Identities = 16/49 (32%), Positives = 24/49 (48%), Gaps = 4/49 (8%)
Query: 1808 VDVTSFAGHPCTR----ASGHPCLNGASCVPREAAYVCLCPGGFSGPHC 1852
V V + G C+ + C +GA+C R A++ C CP G +G C
Sbjct: 322 VCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLC 370
Score = 32.7 bits (73), Expect = 3.7
Identities = 15/45 (33%), Positives = 22/45 (48%), Gaps = 4/45 (8%)
Query: 1813 FAGHPC----TRASGHPCLNGASCVPREAAYVCLCPGGFSGPHCE 1853
F+G C + +PCLN +C+ A Y C C ++G CE
Sbjct: 783 FSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCE 827
Score = 32.7 bits (73), Expect = 3.7
Identities = 16/44 (36%), Positives = 22/44 (50%), Gaps = 5/44 (11%)
Query: 1817 PCTRASGHPCLNGASCVPRE--AAYVCLCPGGFSGPHCEKGLVE 1858
PC + PC NG C E ++ C+CP G+ G CE + E
Sbjct: 832 PCAPS---PCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINE 872
Score = 32.3 bits (72), Expect = 4.9
Identities = 16/48 (33%), Positives = 20/48 (41%), Gaps = 3/48 (6%)
Query: 1320 GRRPPAPQQPPKPCDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCE 1367
G P C+S PC H G C+D G+ C C G G C+
Sbjct: 707 GYHDPTCLSEVNECNSNPCVH-GACRDSL--NGYKCDCDPGWSGTNCD 751
Score = 32.3 bits (72), Expect = 4.9
Identities = 13/36 (36%), Positives = 19/36 (52%), Gaps = 1/36 (2%)
Query: 1332 PC-DSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVC 1366
PC PC++ GTC+ + + C CPA G +C
Sbjct: 1390 PCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLC 1425
Score = 32.0 bits (71), Expect = 6.4
Identities = 14/36 (38%), Positives = 19/36 (52%), Gaps = 1/36 (2%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEK 1368
C + PC +GGTC D + C CP G G C++
Sbjct: 106 CLTNPCRNGGTC-DLLTLTEYKCRCPPGWSGKSCQQ 140
Score = 32.0 bits (71), Expect = 6.4
Identities = 22/65 (33%), Positives = 25/65 (38%), Gaps = 7/65 (10%)
Query: 1305 PTTRRPPTTAPSRVPGRRPPAPQQPPKPCD--SQPCFHGGTCQDWALGGGFTCSCPAGRG 1362
P + T PS G PA Q C + PC H G C + G F C C G
Sbjct: 391 PVNGKAICTCPSGYTG---PACSQDVDECSLGANPCEHAGKCINTL--GSFECQCLQGYT 445
Query: 1363 GAVCE 1367
G CE
Sbjct: 446 GPRCE 450
Score = 32.0 bits (71), Expect = 6.4
Identities = 10/30 (33%), Positives = 17/30 (56%)
Query: 1824 HPCLNGASCVPREAAYVCLCPGGFSGPHCE 1853
+PC + C+ ++ C C G++GP CE
Sbjct: 421 NPCEHAGKCINTLGSFECQCLQGYTGPRCE 450
Score = 32.0 bits (71), Expect = 6.4
Identities = 11/29 (37%), Positives = 17/29 (58%)
Query: 1825 PCLNGASCVPREAAYVCLCPGGFSGPHCE 1853
PCL+ C+ + + C CP GF+G C+
Sbjct: 498 PCLHNGRCLDKINEFQCECPTGFTGHLCQ 526
Score = 31.6 bits (70), Expect = 8.3
Identities = 16/35 (45%), Positives = 18/35 (51%), Gaps = 3/35 (8%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCE 1367
CD PC H G+C+D FTC C G G CE
Sbjct: 570 CDPDPC-HYGSCKDGV--ATFTCLCRPGYTGHHCE 601
Score = 31.6 bits (70), Expect = 8.3
Identities = 17/44 (38%), Positives = 21/44 (47%), Gaps = 4/44 (9%)
Query: 1338 CFHGGTCQDWALGGGFTCSCPAGRGGAVCEKVLG--APVPAFEG 1379
C HGG C D G C C AG G+ CE ++ +P P G
Sbjct: 1116 CQHGGLCVD--AGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNG 1157
>gi|55770876 notch4 preproprotein [Homo sapiens]
Length = 2003
Score = 112 bits (279), Expect = 5e-24
Identities = 227/1003 (22%), Positives = 321/1003 (32%), Gaps = 233/1003 (23%)
Query: 169 PDACRG-MLCGFGAVCE---------PNAEGPGRASCVCKKSP------CPSVVAPVCGS 212
PD C+ LC G C+ P++ P S +C P C + + C
Sbjct: 65 PDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPP 124
Query: 213 DASTYSNECELQRAQCSQQRRIRLLSRGPCGSRDPCSNVTCSFGSTCARSADGLTASCLC 272
+ C +Q + Q + + C RD CS C G C + + C C
Sbjct: 125 SFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQI--QCHC 182
Query: 273 PATCRGAPEGTVCGSDGADYPGECQLLRRACARQENVFKKFDGPCDP---CQGALPDPSR 329
P G AC R N + GPC C L
Sbjct: 183 PPGFEG----------------------HACERDVNECFQDPGPCPKGTSCHNTLGSFQC 220
Query: 330 SCRVNPRTRRPEMLLRPESCPARQAPVCGDDGVTYEND-------CVMGRSGAARGLLLQ 382
C V R E LR CP R G + E D C G G +
Sbjct: 221 LCPVGQEGPRCE--LRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPD 278
Query: 383 KVRSGQCQGRDQCPEPC-RFNAVCLSRRGRPRCSCDRVTCDGAYRPVCAQDGRTYDSDCW 441
S QCQ C + + +C CS D C+ P C ++G T +
Sbjct: 279 NCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHC-RNGGTCQNSAG 337
Query: 442 RQQAECRQQRAIPSKHQGPCDQAPSPCLGVQCAFGATCAVKNGQAACECLQACSSLY--- 498
C + C++ C+ CA G+TC + G +C C + L
Sbjct: 338 SFHCVC-----VSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHL 392
Query: 499 -----------DPVCGSDGVT-----------YGSACELEATACTLGREIQVARKGPCDR 536
D C ++ +T G C + C + ++ PC+
Sbjct: 393 EDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQ----GPSPCEH 448
Query: 537 CGQCRFGALCEAETGRCVCP-----SECVA-----LAQPVCGSDGHTYPSECMLHVHACT 586
G C L + C+CP S C A L+QP +P L + A
Sbjct: 449 GGSC----LNTPGSFNCLCPPGYTGSRCEADHNECLSQP-------CHPGSTCLDLLATF 497
Query: 587 HQISLHVASAGPCET----CGDAVCAFGAVC----SAGQCVC------PRCEHPPPGPVC 632
H + CE C A C A C + QC+C RCE C
Sbjct: 498 HCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDI--DEC 555
Query: 633 GSDGVTYGSACELREAA----CLQ-------QTQIEEARAGPCEQAE------------C 669
S G C+ + A CL QT+++E + PC C
Sbjct: 556 RSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLC 615
Query: 670 GSGGSGS-GEDGDCEQELCRQRGGIWDEDSEDGPCVCDFSCQSVPGSPVCG--SDGVT-Y 725
SG +G E C LC+ + I + + C+C GSP C D T +
Sbjct: 616 PSGFTGQLCEVPLCAPNLCQPK-QICKDQKDKANCLCP------DGSPGCAPPEDNCTCH 668
Query: 726 STECELKKA---------RCESQRGLYVAAQGACRGPTFAPLPPVAPLHCAQTPYG-CCQ 775
C+ CE++ G ++A A G T P P C G C
Sbjct: 669 HGHCQRSSCVCDVGWTGPECEAELGGCISAPCA-HGGTCYPQPSGYNCTCPTGYTGPTCS 727
Query: 776 DNITAARGVGLAGCPSACQCNPHGSYGGTCDPATG--QCSCRPGVGGLRC----DRCEPG 829
+ +TA C S N GG+C+P+ G C+C P G +C D C
Sbjct: 728 EEMTA--------CHSGPCLN-----GGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSA 774
Query: 830 FWNFRGIVTDGRSGCTPCSCDP-------QGAVRDDC--EQMTGLCSCKPGVAGPKCGQC 880
F G R G C C +G +R C +C+ GP+C C
Sbjct: 775 PC-FNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRC-LC 832
Query: 881 PDGRALGPAGCEADASAPATCAEMRCEFGARCVEESGSAHCVC------PMLTCPEANAT 934
P G G D CA+ C + C++ S HC+C P+ P ++
Sbjct: 833 PTGYTGGSCQTLMD-----LCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQ 887
Query: 935 KVCGSDGVTYGNECQLKTIA----------CRQGLQISIQSLGPCQEAVAP-STHPTSAS 983
K S G+ + C + C G Q S+ CQ+ V P + P
Sbjct: 888 KAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSL-----CQDHVNPCESRPCQNG 942
Query: 984 VT-VTTPGLLLSQALPAPPG-----ALPLAPSSTAHSQTTPPP 1020
T + P L Q P G L S H+ T P
Sbjct: 943 ATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTP 985
Score = 92.0 bits (227), Expect = 5e-18
Identities = 209/932 (22%), Positives = 278/932 (29%), Gaps = 239/932 (25%)
Query: 152 CVEDKPGTHFTPVPPTPPDACRGMLCGFGAVCEPNAEGPGRASCVCKKSPCPSVVAPVCG 211
C D P P +C L F +C EGP C + PCP P
Sbjct: 191 CERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGP---RCELRAGPCP----PRGC 243
Query: 212 SDASTYSNECELQRAQCSQQRRIRLLSRGPCG-----SRDPCSNVTCSFGSTCARSADGL 266
S+ T C+L + S + L G G + D C + C G TC D
Sbjct: 244 SNGGT----CQLMPEKDS-TFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLD-- 296
Query: 267 TASCLCPATCRG-----------------APEGTVCGSDGADYPGECQLLRRACARQENV 309
T +CLCP T G G C + + C + +EN+
Sbjct: 297 TYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENL 356
Query: 310 FKKFDGPCDPCQ---------GALPDPSRS--------------------CRVNPRTRRP 340
C P L P R+ C NP T
Sbjct: 357 DDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGST 416
Query: 341 EMLLRPESCPARQAPVCGDDGVTYENDCVMGRSGAA----RGLLLQKVRSGQC------- 389
L + P P C D ++C+M + G + G L S C
Sbjct: 417 LCLCQ----PGYSGPTCHQD----LDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYT 468
Query: 390 -----QGRDQC-PEPCRFNAVCLSRRGRPRCSCDRVTCDGAYRPVCAQDGRTYDSDCWRQ 443
++C +PC + CL C C G +C + S
Sbjct: 469 GSRCEADHNECLSQPCHPGSTCLDLLATFHCLCP----PGLEGQLCEVETNECASAPCLN 524
Query: 444 QAECR------QQRAIPSKHQGPCDQAPSPCLGVQCAFGATCAVKNGQAACECLQA---- 493
A+C Q +P C++ C CA G C + G C+CL
Sbjct: 525 HADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGP 584
Query: 494 -CSSLYDPVCGSDGVTYGSAC-ELEAT---ACTLGREIQVARKGPCDRCGQCRFGALC-- 546
C + D C SD G++C +L C G Q+ C C+ +C
Sbjct: 585 RCQTEVDE-CLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLC-APNLCQPKQICKD 642
Query: 547 EAETGRCVCPSECVALAQPVCGSDGHTYPSECMLHVHACTHQISLHVASAGP-CET---- 601
+ + C+CP A P H H H V GP CE
Sbjct: 643 QKDKANCLCPDGSPGCAPPEDNCTCH--------HGHCQRSSCVCDVGWTGPECEAELGG 694
Query: 602 CGDAVCAFGAVC----SAGQCVCPRCEHPPPGPVCGSDGVTYGSACELREAACLQQ---- 653
C A CA G C S C CP GP C + S L +C
Sbjct: 695 CISAPCAHGGTCYPQPSGYNCTCPT---GYTGPTCSEEMTACHSGPCLNGGSCNPSPGGY 751
Query: 654 -TQIEEARAGP--------CEQAECGSGGSGSGEDG---------------------DCE 683
+ GP C A C +GG+ G C
Sbjct: 752 YCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCA 811
Query: 684 QELCRQRGGIWDEDSEDGP-CVCDF-----SCQSV---------PGSPVCGSDGVTY--- 725
CR R +DS GP C+C SCQ++ P + C G ++
Sbjct: 812 DSPCRNRATC--QDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCL 869
Query: 726 ------STECELKKARCES---QRGLYVAA----QGAC--RGPTFAPLPPVAPLHCAQTP 770
C L + C+ +G+ V++ G C GP++ HC
Sbjct: 870 CLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYF-------CHCPPGF 922
Query: 771 YG-CCQDNIT------AARGVGLAGCPSA--CQCNPHGSYGGTCDPATGQC--------- 812
G CQD++ G PS CQC P G G C C
Sbjct: 923 QGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAP-GYDGQNCSKELDACQSQPCHNHG 981
Query: 813 SCRPGVGGLRCDRCEPGFWNFR--GIVTDGRSGCTPCSCDPQGAVRDDCEQMTGLCSCKP 870
+C P GG C C PGF R G V + C C P G C C P
Sbjct: 982 TCTPKPGGFHC-ACPPGFVGLRCEGDVDE----CLDQPCHPTGTAACHSLANAFYCQCLP 1036
Query: 871 GVAGPKC----GQCPDGRALGPAGCEADASAP 898
G G C C CEA A +P
Sbjct: 1037 GHTGQWCEVEIDPCHSQPCFHGGTCEATAGSP 1068
Score = 78.6 bits (192), Expect = 6e-14
Identities = 128/549 (23%), Positives = 180/549 (32%), Gaps = 136/549 (24%)
Query: 396 PEPCRFNAVCLS-RRGRPRCSCDRVTCDGAYRPVCAQDGRTYDSDCWRQQAECRQQRAIP 454
PEPC CLS G+ C C G C ++ + C Q +P
Sbjct: 32 PEPCANGGTCLSLSLGQGTCQC----APGFLGETCQFPDPCQNAQLCQNGGSC--QALLP 85
Query: 455 SKHQGPCDQAPSPCLGVQCAFGATCAVKNGQAACECLQACSSLYDPVCGSDGVTYGSACE 514
+ P +PSP + +F TC C+ + L DP C + C
Sbjct: 86 APLGLP--SSPSP---LTPSFLCTCLPGFTGERCQ-----AKLEDP-CPPSFCSKRGRCH 134
Query: 515 LEATACTLGREIQVARKGPCDRCGQCRFGALCEAETGRCVCPSECVALAQPVCGSDGHTY 574
++A+ GR G QC+ C A CV C+A TY
Sbjct: 135 IQAS----GRPQCSCMPGWTGE--QCQLRDFCSANP--CVNGGVCLA-----------TY 175
Query: 575 PS-ECM----LHVHACTHQISLHVASAGPC---ETCGDAVCAFGAVCSAGQCVCPRCEHP 626
P +C HAC ++ GPC +C + + +F +C GQ
Sbjct: 176 PQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQ--------- 226
Query: 627 PPGPVCGSDGVTYGSACELREAACLQQTQIEEARAGPCEQAECGSGGSGS-GEDGDCEQE 685
GP C E RAGPC C +GG+ + D
Sbjct: 227 -EGPRC-------------------------ELRAGPCPPRGCSNGGTCQLMPEKDSTFH 260
Query: 686 LCRQRGGIWDEDSEDGP-------CVCDFSCQSVPGSPVCGSDGVTYSTECELKKARCES 738
LC G D E P C +CQ + C +C CE+
Sbjct: 261 LCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECET 320
Query: 739 QRGLYVAAQGACRGPTFAPLPPVAPLHCAQTPYGCCQDNITAARGVGLAGC-PSACQCNP 797
Q P HC G CQ++ + V ++G ++C+ N
Sbjct: 321 Q----------------------GPPHCRNG--GTCQNSAGSFHCVCVSGWGGTSCEENL 356
Query: 798 HGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDPQGAVRD 857
TC P + +C VG C C PG G++ C C G +
Sbjct: 357 DDCIAATCAPGS---TCIDRVGSFSC-LCPPG---RTGLLCHLEDMCLSQPC--HGDAQC 407
Query: 858 DCEQMTG--LCSCKPGVAGPKCGQCPDGRALGPAGCEADASAPATCAEMRCEFGARCVEE 915
+TG LC C+PG +GP C Q + D A CE G C+
Sbjct: 408 STNPLTGSTLCLCQPGYSGPTCHQ------------DLDECLMAQQGPSPCEHGGSCLNT 455
Query: 916 SGSAHCVCP 924
GS +C+CP
Sbjct: 456 PGSFNCLCP 464
Score = 76.3 bits (186), Expect = 3e-13
Identities = 183/816 (22%), Positives = 243/816 (29%), Gaps = 175/816 (21%)
Query: 172 CRGMLCGFGAVCEPNAEGPGRASCV--CKKSPCPSVVAPVCGSDASTYSNEC--ELQRAQ 227
C +L GF +C P G + C+ SPC + C + +C + +
Sbjct: 528 CHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCAN--GGQCQDQPGAFHCKCLPGFEGPR 585
Query: 228 CSQQRRIRLLSRGPCGSRDPCSNVTCSFGSTCARSADGLTASCLCPATCRGAP-EGTVCG 286
C + D C + C G++C CLCP+ G E +C
Sbjct: 586 CQTEV-------------DECLSDPCPVGASCLDLPGAFF--CLCPSGFTGQLCEVPLCA 630
Query: 287 SDGADYPGECQLLRRACARQENVFKKFDGPCDPCQGALPDPSRSCRVNPRTRRPEMLLRP 346
P CQ ++ C Q+ D PD S C PE
Sbjct: 631 ------PNLCQP-KQICKDQK----------DKANCLCPDGSPGCAP------PE----- 662
Query: 347 ESCPARQAPVCGDDGVTYENDCV--MGRSGAARGLLLQKVRSGQCQGRDQC-PEPCRFNA 403
++C G + CV +G +G L S C C P+P +N
Sbjct: 663 DNCTCHH-------GHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNC 715
Query: 404 VCLSRRGRPRCSCDRVTCDGAYRPVCAQDGRTYDSDCWRQQAECRQQRAIPSKHQGP-CD 462
C + P CS + C C G S C P H GP C
Sbjct: 716 TCPTGYTGPTCSEEMTACHSG---PCLNGGSCNPSP-GGYYCTC------PPSHTGPQCQ 765
Query: 463 QAPSPCLGVQCAFGATCAVKNGQAACECLQA-----CSSLYDPVCGSDGVTYGSACELEA 517
+ C+ C G TC + G +C C C P C S C A
Sbjct: 766 TSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCAD------SPCRNRA 819
Query: 518 TACTLGREIQVARKGPCDRCGQCRFGALCEAETGRCVCPSECVALAQPVCGSDGH---TY 574
T Q + +GP C G C+ C AQ C + H T
Sbjct: 820 TC-------QDSPQGPRCLCPTGYTGGSCQTLMDLC---------AQKPCPRNSHCLQTG 863
Query: 575 PSECMLHVHACTHQISLHVASAGPCETCGDAVCAFGAVCSAGQCVCPRCEHPPPGPVCGS 634
PS L + T GP + C A+ S G V C + G +C
Sbjct: 864 PSFHCLCLQGWT----------GPLCNLPLSSCQKAAL-SQGIDVSSLCHN---GGLCVD 909
Query: 635 DGVTYGSACELREAACLQQTQIEEARAGPCEQ-AECGSGGSG------SGEDG-DCEQEL 686
G +Y C L Q + + PC+ A C + SG G DG +C +EL
Sbjct: 910 SGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKEL 969
Query: 687 CRQRGGIWDEDSEDGPCVCDFSCQSVPGSPVCGSDGVTYSTECELKKARCESQRGLYVAA 746
+ + PC +C PG C CE C Q +
Sbjct: 970 ---------DACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQP-CHPTG 1019
Query: 747 QGACRGPTFAPLPPVAPLHCAQTPYGCCQDNITAARGVGLAGCPSACQCNPHGSYGGTCD 806
AC A P H Q C+ I C P +GGTC+
Sbjct: 1020 TAACHSLANAFYCQCLPGHTGQW----CEVEI------------DPCHSQPC-FHGGTCE 1062
Query: 807 PATGQ-----CSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDPQGAVRDDCEQ 861
G C C G G C P G G S P R
Sbjct: 1063 ATAGSPLGFICHCPKGFEGPTCSHRAPSC----GFHHCHHGGLCLPSPKPGFPPR----- 1113
Query: 862 MTGLCSCKPGVAGPKCGQCPDGRALG-PAGCEADASAPATCAEMRCEFGARCVEESGSAH 920
C+C G GP C P + G P+ C + S T F C S
Sbjct: 1114 ----CACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPR 1169
Query: 921 CVCP-MLTCPEANATKVC-----GSDGVTYGNECQL 950
C P C + C G G G +C L
Sbjct: 1170 CQKPGAKGCEGRSGDGACDAGCSGPGGNWDGGDCSL 1205
Score = 69.3 bits (168), Expect = 4e-11
Identities = 34/80 (42%), Positives = 38/80 (47%), Gaps = 4/80 (5%)
Query: 1548 CGDH--PCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRV 1605
C DH PC PC GA C +G + CQC PG G C+ E CQ PCH C
Sbjct: 927 CQDHVNPCESRPCQNGATCMAQPSG-YLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTP 985
Query: 1606 LPEGGAQCECPLGREGTFCQ 1625
P GG C CP G G C+
Sbjct: 986 KP-GGFHCACPPGFVGLRCE 1004
Score = 68.2 bits (165), Expect = 8e-11
Identities = 34/90 (37%), Positives = 43/90 (47%), Gaps = 5/90 (5%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQ 1612
C+ PC G C +G ++C CP G GPTC++E + C PC C P GG
Sbjct: 695 CISAPCAHGGTCYPQPSG-YNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSP-GGYY 752
Query: 1613 CECPLGREGTFCQTASGQDGSGPFLADFNG 1642
C CP G CQT++ S P FNG
Sbjct: 753 CTCPPSHTGPQCQTSTDYCVSAPC---FNG 779
Score = 65.9 bits (159), Expect = 4e-10
Identities = 38/102 (37%), Positives = 47/102 (46%), Gaps = 8/102 (7%)
Query: 1555 PNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQCE 1614
P+PC G C N G F+C CPPG G C + + C PCH + C L C
Sbjct: 443 PSPCEHGGSCLNTP-GSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDL-LATFHCL 500
Query: 1615 CPLGREGTFCQTASGQDGSGPFL--AD----FNGFSHLELRG 1650
CP G EG C+ + + S P L AD NGF + L G
Sbjct: 501 CPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPG 542
Score = 65.5 bits (158), Expect = 5e-10
Identities = 36/89 (40%), Positives = 42/89 (47%), Gaps = 2/89 (2%)
Query: 1547 ECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVL 1606
E + CL PCH G+ C +L A FHC CPPG G C E + C PC A C L
Sbjct: 473 EADHNECLSQPCHPGSTCLDLLA-TFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDL 531
Query: 1607 PEGGAQCECPLGREGTFCQTASGQDGSGP 1635
G QC C G GT C+ + S P
Sbjct: 532 -LNGFQCICLPGFSGTRCEEDIDECRSSP 559
Score = 65.1 bits (157), Expect = 7e-10
Identities = 31/73 (42%), Positives = 37/73 (50%), Gaps = 2/73 (2%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQ 1612
C +PC G CQ+ + G FHC+C PG GP C E C +PC A C LP G
Sbjct: 555 CRSSPCANGGQCQD-QPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLP-GAFF 612
Query: 1613 CECPLGREGTFCQ 1625
C CP G G C+
Sbjct: 613 CLCPSGFTGQLCE 625
Score = 62.8 bits (151), Expect = 3e-09
Identities = 34/82 (41%), Positives = 36/82 (43%), Gaps = 6/82 (7%)
Query: 1545 VGECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCR 1604
V EC D PC P G A C +L A F+CQC PG G C E PC PC C
Sbjct: 1007 VDECLDQPCHPT---GTAACHSL-ANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCE 1062
Query: 1605 VLPEG--GAQCECPLGREGTFC 1624
G C CP G EG C
Sbjct: 1063 ATAGSPLGFICHCPKGFEGPTC 1084
Score = 60.1 bits (144), Expect = 2e-08
Identities = 28/74 (37%), Positives = 34/74 (45%), Gaps = 4/74 (5%)
Query: 1555 PNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQ-- 1612
P PC G C N G F C CP G+ GP C PC P C C+++PE +
Sbjct: 202 PGPCPKGTSCHNT-LGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFH 260
Query: 1613 -CECPLGREGTFCQ 1625
C CP G G C+
Sbjct: 261 LCLCPPGFIGPDCE 274
Score = 59.3 bits (142), Expect = 4e-08
Identities = 30/75 (40%), Positives = 36/75 (48%), Gaps = 3/75 (4%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSP-CQPNPCHGAAPCRVLPEGGA 1611
C+ PC G C N G F C C G GP C + P C +PC A C+ P+G
Sbjct: 771 CVSAPCFNGGTCVN-RPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQG-P 828
Query: 1612 QCECPLGREGTFCQT 1626
+C CP G G CQT
Sbjct: 829 RCLCPTGYTGGSCQT 843
Score = 59.3 bits (142), Expect = 4e-08
Identities = 29/75 (38%), Positives = 34/75 (45%), Gaps = 4/75 (5%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCH--GAAPCRVLPEGG 1610
C PCH C + G FHC CPPG VG C + C PCH G A C L
Sbjct: 972 CQSQPCHNHGTCTP-KPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSL-ANA 1029
Query: 1611 AQCECPLGREGTFCQ 1625
C+C G G +C+
Sbjct: 1030 FYCQCLPGHTGQWCE 1044
Score = 58.9 bits (141), Expect = 5e-08
Identities = 33/89 (37%), Positives = 38/89 (42%), Gaps = 7/89 (7%)
Query: 1553 CLPNPCHGGAPCQ-NLEAGRFHCQCPPGRVGPTCADEKSPC-----QPNPCHGAAPCRVL 1606
CL PCHG A C N G C C PG GPTC + C P+PC C
Sbjct: 396 CLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNT 455
Query: 1607 PEGGAQCECPLGREGTFCQTASGQDGSGP 1635
P G C CP G G+ C+ + S P
Sbjct: 456 P-GSFNCLCPPGYTGSRCEADHNECLSQP 483
Score = 57.4 bits (137), Expect = 1e-07
Identities = 26/67 (38%), Positives = 31/67 (46%), Gaps = 2/67 (2%)
Query: 1558 CHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQCECPL 1617
CH G C + F C CPPG G C D +PC+ PC A C P G C+C
Sbjct: 901 CHNGGLCVDSGPSYF-CHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQP-SGYLCQCAP 958
Query: 1618 GREGTFC 1624
G +G C
Sbjct: 959 GYDGQNC 965
Score = 55.5 bits (132), Expect = 5e-07
Identities = 30/88 (34%), Positives = 35/88 (39%), Gaps = 4/88 (4%)
Query: 1552 PCLPNPCHGGAPCQNLEAGR--FHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEG 1609
PC PC G C+ F C CP G GPTC+ C + CH C P+
Sbjct: 1049 PCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKP 1108
Query: 1610 G--AQCECPLGREGTFCQTASGQDGSGP 1635
G +C C G G C T G GP
Sbjct: 1109 GFPPRCACLSGYGGPDCLTPPAPKGCGP 1136
Score = 55.1 bits (131), Expect = 7e-07
Identities = 31/89 (34%), Positives = 40/89 (44%), Gaps = 2/89 (2%)
Query: 1547 ECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVL 1606
E + C PC A C +L G F C C PG G C ++ C+ +PC C+
Sbjct: 511 EVETNECASAPCLNHADCHDLLNG-FQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQ 569
Query: 1607 PEGGAQCECPLGREGTFCQTASGQDGSGP 1635
P G C+C G EG CQT + S P
Sbjct: 570 P-GAFHCKCLPGFEGPRCQTEVDECLSDP 597
Score = 53.9 bits (128), Expect = 2e-06
Identities = 28/79 (35%), Positives = 35/79 (44%), Gaps = 4/79 (5%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPC--QPNPCHGAAPCRVLPEGG 1610
C NPC G C + C CPPG G C + + C P PC C G
Sbjct: 160 CSANPCVNGGVCLATYP-QIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTL-GS 217
Query: 1611 AQCECPLGREGTFCQTASG 1629
QC CP+G+EG C+ +G
Sbjct: 218 FQCLCPVGQEGPRCELRAG 236
Score = 53.5 bits (127), Expect = 2e-06
Identities = 25/73 (34%), Positives = 30/73 (41%), Gaps = 2/73 (2%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQ 1612
C PC G C N G ++C CPP GP C C PC C P G
Sbjct: 733 CHSGPCLNGGSC-NPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRP-GTFS 790
Query: 1613 CECPLGREGTFCQ 1625
C C +G +G C+
Sbjct: 791 CLCAMGFQGPRCE 803
Score = 50.8 bits (120), Expect = 1e-05
Identities = 26/70 (37%), Positives = 30/70 (42%), Gaps = 2/70 (2%)
Query: 1555 PNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQCE 1614
P C G CQN AG FHC C G G +C + C C + C + G C
Sbjct: 323 PPHCRNGGTCQN-SAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTC-IDRVGSFSCL 380
Query: 1615 CPLGREGTFC 1624
CP GR G C
Sbjct: 381 CPPGRTGLLC 390
Score = 48.5 bits (114), Expect = 7e-05
Identities = 37/117 (31%), Positives = 44/117 (37%), Gaps = 19/117 (16%)
Query: 1548 CGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQ-PNPCHGAAPCRVL 1606
CG P PC G C +L G+ CQC PG +G TC PCQ C C+ L
Sbjct: 28 CGS---FPEPCANGGTCLSLSLGQGTCQCAPGFLGETC-QFPDPCQNAQLCQNGGSCQAL 83
Query: 1607 ---PEG----------GAQCECPLGREGTFCQTASGQDGSGPFLADFNGFSHLELRG 1650
P G C C G G CQ A +D P G H++ G
Sbjct: 84 LPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQ-AKLEDPCPPSFCSKRGRCHIQASG 139
Score = 48.1 bits (113), Expect = 9e-05
Identities = 22/38 (57%), Positives = 23/38 (60%), Gaps = 5/38 (13%)
Query: 1332 PCDSQPCFHGGTCQDWALGG---GFTCSCPAGRGGAVC 1366
PC SQPCFHGGTC+ A G GF C CP G G C
Sbjct: 1049 PCHSQPCFHGGTCE--ATAGSPLGFICHCPKGFEGPTC 1084
Score = 46.6 bits (109), Expect = 2e-04
Identities = 32/114 (28%), Positives = 40/114 (35%), Gaps = 20/114 (17%)
Query: 1532 LGIGPGAATRGSGVGECGDHPCLPNPCHGGAPCQNLEAGR-------------------F 1572
L + G T G G+ P+PC CQN + + F
Sbjct: 42 LSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSF 101
Query: 1573 HCQCPPGRVGPTC-ADEKSPCQPNPCHGAAPCRVLPEGGAQCECPLGREGTFCQ 1625
C C PG G C A + PC P+ C C + G QC C G G CQ
Sbjct: 102 LCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQ 155
Score = 46.2 bits (108), Expect = 3e-04
Identities = 29/101 (28%), Positives = 38/101 (37%), Gaps = 23/101 (22%)
Query: 1552 PCLPNPCHGGAPCQNL--EAGRFH-CQCPPGRVGPTCADEKSPCQPNPCHGAAPCR---- 1604
PC P C G CQ + + FH C CPPG +GP C C + C C+
Sbjct: 237 PCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLD 296
Query: 1605 ----VLPEGGAQCEC------------PLGREGTFCQTASG 1629
+ PE +C P R G CQ ++G
Sbjct: 297 TYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAG 337
Score = 45.1 bits (105), Expect = 7e-04
Identities = 26/81 (32%), Positives = 27/81 (33%), Gaps = 1/81 (1%)
Query: 1557 PCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQCECP 1616
P C + R C C G GP C E C PC C P G C CP
Sbjct: 660 PPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQP-SGYNCTCP 718
Query: 1617 LGREGTFCQTASGQDGSGPFL 1637
G G C SGP L
Sbjct: 719 TGYTGPTCSEEMTACHSGPCL 739
Score = 45.1 bits (105), Expect = 7e-04
Identities = 19/47 (40%), Positives = 22/47 (46%), Gaps = 4/47 (8%)
Query: 1811 TSFAGHPC----TRASGHPCLNGASCVPREAAYVCLCPGGFSGPHCE 1853
T + G C T PCLNG SC P Y C CP +GP C+
Sbjct: 719 TGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQ 765
Score = 45.1 bits (105), Expect = 7e-04
Identities = 22/56 (39%), Positives = 28/56 (50%), Gaps = 5/56 (8%)
Query: 1812 SFAGHPCTRASGH----PCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVEKSAGD 1863
S G C ++ + PC NG +CV R + CLC GF GP CE G + S D
Sbjct: 758 SHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCE-GKLRPSCAD 812
Score = 43.5 bits (101), Expect = 0.002
Identities = 24/56 (42%), Positives = 28/56 (50%), Gaps = 2/56 (3%)
Query: 1318 VPGRRPPAPQQPPKPCDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEKVLGAP 1373
+PG P Q C S PC G +C D L G F C CP+G G +CE L AP
Sbjct: 578 LPGFEGPRCQTEVDECLSDPCPVGASCLD--LPGAFFCLCPSGFTGQLCEVPLCAP 631
Score = 42.4 bits (98), Expect = 0.005
Identities = 14/38 (36%), Positives = 23/38 (60%)
Query: 1825 PCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVEKSAG 1862
PC +G +C P+ + Y C CP G++GP C + + +G
Sbjct: 699 PCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSG 736
Score = 42.0 bits (97), Expect = 0.006
Identities = 28/85 (32%), Positives = 35/85 (41%), Gaps = 16/85 (18%)
Query: 1553 CLPNPCHGGAPCQNLEAG-RFHCQCPPGRVGPTCADEKSPCQ----------PNPCHGAA 1601
C PC + C L+ G FHC C G GP C S CQ + CH
Sbjct: 848 CAQKPCPRNSHC--LQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGG 905
Query: 1602 PCRVLPEGGAQ-CECPLGREGTFCQ 1625
C + G + C CP G +G+ CQ
Sbjct: 906 LC--VDSGPSYFCHCPPGFQGSLCQ 928
Score = 42.0 bits (97), Expect = 0.006
Identities = 21/54 (38%), Positives = 26/54 (48%), Gaps = 2/54 (3%)
Query: 1319 PGRRPPAPQQPPKPCDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEKVLGA 1372
PG + Q PC+S+PC +G TC A G+ C C G G C K L A
Sbjct: 920 PGFQGSLCQDHVNPCESRPCQNGATCM--AQPSGYLCQCAPGYDGQNCSKELDA 971
Score = 41.6 bits (96), Expect = 0.008
Identities = 64/278 (23%), Positives = 82/278 (29%), Gaps = 65/278 (23%)
Query: 777 NITAARGVGLAGCPSACQCNPHGSYGGTC---DPATGQCSCRPGVGGLRC---DRCEPGF 830
++ RG+ P C + GGTC G C C PG G C D C+
Sbjct: 19 SVVRPRGLLCGSFPEPC------ANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQ--- 69
Query: 831 WNFRGIVTDGRSGCTPCSCDPQGAVRDDCEQMTG-LCSCKPGVAGPKCGQCPDGRALGPA 889
+ C P G LC+C PG G +C
Sbjct: 70 ---NAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERC------------ 114
Query: 890 GCEADASAPATCAEMRCEFGARC-VEESGSAHCVC-PMLTCPEANATKVCGSDGVTYGNE 947
A C C RC ++ SG C C P T + C ++ G
Sbjct: 115 ----QAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFCSANPCVNGGV 170
Query: 948 C-------------QLKTIACRQGLQISIQSLGPCQEAVAPSTHPTSASVTVTTP----- 989
C + AC + + Q GPC + S H T S P
Sbjct: 171 CLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGT--SCHNTLGSFQCLCPVGQEG 228
Query: 990 GLLLSQALPAPP------GALPLAP--SSTAHSQTTPP 1019
+A P PP G L P ST H PP
Sbjct: 229 PRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPP 266
Score = 41.6 bits (96), Expect = 0.008
Identities = 16/41 (39%), Positives = 24/41 (58%), Gaps = 3/41 (7%)
Query: 1816 HPCTRASGHPCLNGASCVPREAAYVCLCPGGFSGPHCEKGL 1856
+PC PC NGA+C+ + + Y+C C G+ G +C K L
Sbjct: 932 NPC---ESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKEL 969
Score = 41.2 bits (95), Expect = 0.010
Identities = 17/40 (42%), Positives = 22/40 (55%), Gaps = 2/40 (5%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEKVLGA 1372
C S PC HGGTC + G+ C+CP G G C + + A
Sbjct: 695 CISAPCAHGGTC--YPQPSGYNCTCPTGYTGPTCSEEMTA 732
Score = 40.8 bits (94), Expect = 0.014
Identities = 16/29 (55%), Positives = 19/29 (65%)
Query: 1825 PCLNGASCVPREAAYVCLCPGGFSGPHCE 1853
PC GASC+ A+ CLCP GF+G CE
Sbjct: 597 PCPVGASCLDLPGAFFCLCPSGFTGQLCE 625
Score = 40.0 bits (92), Expect = 0.023
Identities = 24/73 (32%), Positives = 29/73 (39%), Gaps = 4/73 (5%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGA- 1611
C +PC A CQ+ G C CP G G +C C PC + C L G +
Sbjct: 810 CADSPCRNRATCQDSPQGP-RCLCPTGYTGGSCQTLMDLCAQKPCPRNSHC--LQTGPSF 866
Query: 1612 QCECPLGREGTFC 1624
C C G G C
Sbjct: 867 HCLCLQGWTGPLC 879
Score = 39.7 bits (91), Expect = 0.031
Identities = 19/47 (40%), Positives = 21/47 (44%), Gaps = 6/47 (12%)
Query: 1813 FAGHPCTRASGH------PCLNGASCVPREAAYVCLCPGGFSGPHCE 1853
F GH C R PC G SC ++ CLCP G GP CE
Sbjct: 186 FEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCE 232
Score = 39.3 bits (90), Expect = 0.040
Identities = 18/35 (51%), Positives = 20/35 (57%), Gaps = 2/35 (5%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCE 1367
C SQPC + GTC GGF C+CP G G CE
Sbjct: 972 CQSQPCHNHGTCTPKP--GGFHCACPPGFVGLRCE 1004
Score = 39.3 bits (90), Expect = 0.040
Identities = 21/48 (43%), Positives = 26/48 (54%), Gaps = 5/48 (10%)
Query: 1323 PPAPQQPPKPCDSQPCFHGGTCQDWA-LGG-GFTCSCPAGRGGAVCEK 1368
PPAP+ P PC + G+C + LGG GF CSCP G C+K
Sbjct: 1128 PPAPKGCGPP---SPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQK 1172
Score = 38.9 bits (89), Expect = 0.052
Identities = 19/57 (33%), Positives = 25/57 (43%), Gaps = 12/57 (21%)
Query: 1813 FAGHPCTR----ASGHPCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVEKSAGDVD 1865
+ G C++ PC N +C P+ + C CP GF G CE GDVD
Sbjct: 960 YDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCE--------GDVD 1008
Score = 38.1 bits (87), Expect = 0.089
Identities = 13/29 (44%), Positives = 19/29 (65%)
Query: 1825 PCLNGASCVPREAAYVCLCPGGFSGPHCE 1853
PC +G SC+ ++ CLCP G++G CE
Sbjct: 445 PCEHGGSCLNTPGSFNCLCPPGYTGSRCE 473
Score = 38.1 bits (87), Expect = 0.089
Identities = 20/49 (40%), Positives = 23/49 (46%), Gaps = 2/49 (4%)
Query: 1319 PGRRPPAPQQPPKPCDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCE 1367
P P Q C S PCF+GGTC + G F+C C G G CE
Sbjct: 757 PSHTGPQCQTSTDYCVSAPCFNGGTCVN--RPGTFSCLCAMGFQGPRCE 803
Score = 38.1 bits (87), Expect = 0.089
Identities = 57/213 (26%), Positives = 69/213 (32%), Gaps = 31/213 (14%)
Query: 170 DACRGMLCGFGAVCEPNAEGPGRASCVCKK---SPCPSVVAPVCGSDASTYSNECELQRA 226
D C C G CE A P C C K P S AP CG + C L
Sbjct: 1048 DPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLC-LPSP 1106
Query: 227 QCSQQRRIRLLS--RGP----------CGSRDPC-SNVTCSFGSTCARSADGLTASCLCP 273
+ R LS GP CG PC N +CS T G SC
Sbjct: 1107 KPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCS--ETTGLGGPGFRCSCPHS 1164
Query: 274 ATCRGAPEGTVCGSDGADYPGECQLLRRACARQENVFKKFDGPCDPCQGALPDPSRSCRV 333
+ + G +G G C C+ +DG C +PDP + C
Sbjct: 1165 SPGPRCQKPGAKGCEGRSGDGACD---AGCSGPGG---NWDG--GDCSLGVPDPWKGC-- 1214
Query: 334 NPRTRRPEMLLRPESC-PARQAPVCGDDGVTYE 365
P R +L R C P + C DG E
Sbjct: 1215 -PSHSRCWLLFRDGQCHPQCDSEECLFDGYDCE 1246
Score = 37.4 bits (85), Expect = 0.15
Identities = 15/37 (40%), Positives = 20/37 (54%)
Query: 1822 SGHPCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVE 1858
S +PC+NG C+ C CP GF G CE+ + E
Sbjct: 161 SANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNE 197
Score = 37.0 bits (84), Expect = 0.20
Identities = 18/41 (43%), Positives = 22/41 (53%), Gaps = 7/41 (17%)
Query: 1327 QQPPKPCDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCE 1367
QQ P PC+ HGG+C + G F C CP G G+ CE
Sbjct: 440 QQGPSPCE-----HGGSCLNTP--GSFNCLCPPGYTGSRCE 473
Score = 37.0 bits (84), Expect = 0.20
Identities = 18/35 (51%), Positives = 19/35 (54%), Gaps = 2/35 (5%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCE 1367
C SQPC G TC D L F C CP G G +CE
Sbjct: 479 CLSQPCHPGSTCLD--LLATFHCLCPPGLEGQLCE 511
Score = 37.0 bits (84), Expect = 0.20
Identities = 13/29 (44%), Positives = 16/29 (55%)
Query: 1825 PCLNGASCVPREAAYVCLCPGGFSGPHCE 1853
PC NG C + A+ C C GF GP C+
Sbjct: 559 PCANGGQCQDQPGAFHCKCLPGFEGPRCQ 587
Score = 37.0 bits (84), Expect = 0.20
Identities = 34/112 (30%), Positives = 40/112 (35%), Gaps = 26/112 (23%)
Query: 1548 CGDHPC------LPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSP--C-QPNPCH 1598
CG H C LP+P G P C C G GP C +P C P+PC
Sbjct: 1091 CGFHHCHHGGLCLPSPKPGFPP---------RCACLSGYGGPDCLTPPAPKGCGPPSPCL 1141
Query: 1599 GAAPCRV---LPEGGAQCECPLGREGTFCQT-----ASGQDGSGPFLADFNG 1642
C L G +C CP G CQ G+ G G A +G
Sbjct: 1142 YNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGACDAGCSG 1193
Score = 36.6 bits (83), Expect = 0.26
Identities = 25/73 (34%), Positives = 31/73 (42%), Gaps = 8/73 (10%)
Query: 1318 VPGRRPPAPQQPPKPCDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVC----EKVLGAP 1373
+PG ++ C S PC +GG CQD G F C C G G C ++ L P
Sbjct: 540 LPGFSGTRCEEDIDECRSSPCANGGQCQDQP--GAFHCKCLPGFEGPRCQTEVDECLSDP 597
Query: 1374 VPAFEGRSFLAFP 1386
P G S L P
Sbjct: 598 CPV--GASCLDLP 608
Score = 36.6 bits (83), Expect = 0.26
Identities = 16/48 (33%), Positives = 22/48 (45%), Gaps = 2/48 (4%)
Query: 1320 GRRPPAPQQPPKPCDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCE 1367
G P + C S PC +GG+C GG+ C+CP G C+
Sbjct: 720 GYTGPTCSEEMTACHSGPCLNGGSCN--PSPGGYYCTCPPSHTGPQCQ 765
Score = 36.2 bits (82), Expect = 0.34
Identities = 19/41 (46%), Positives = 25/41 (60%), Gaps = 5/41 (12%)
Query: 1333 CDSQP---CFHGGTCQDWALGGGFTCSCPAGRGGAVCEKVL 1370
C++Q C +GGTCQ+ A G F C C +G GG CE+ L
Sbjct: 318 CETQGPPHCRNGGTCQNSA--GSFHCVCVSGWGGTSCEENL 356
Score = 35.8 bits (81), Expect = 0.44
Identities = 15/34 (44%), Positives = 19/34 (55%)
Query: 1825 PCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVE 1858
PCLN A C + C+C GFSG CE+ + E
Sbjct: 521 PCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDE 554
Score = 34.7 bits (78), Expect = 0.98
Identities = 15/32 (46%), Positives = 19/32 (59%), Gaps = 1/32 (3%)
Query: 1336 QPCFHGGTCQDWALGGGFTCSCPAGRGGAVCE 1367
+PC +GGTC +LG G TC C G G C+
Sbjct: 33 EPCANGGTCLSLSLGQG-TCQCAPGFLGETCQ 63
Score = 34.3 bits (77), Expect = 1.3
Identities = 15/32 (46%), Positives = 21/32 (65%), Gaps = 4/32 (12%)
Query: 1826 CLNGASC--VPREAA--YVCLCPGGFSGPHCE 1853
C NG +C +P + + ++CLCP GF GP CE
Sbjct: 243 CSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCE 274
Score = 33.9 bits (76), Expect = 1.7
Identities = 19/50 (38%), Positives = 23/50 (46%), Gaps = 2/50 (4%)
Query: 1319 PGRRPPAPQQPPKPCDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEK 1368
PG P + P C S C +GGTCQD +TC CP G C +
Sbjct: 266 PGFIGPDCEVNPDNCVSHQCQNGGTCQDGL--DTYTCLCPETWTGWDCSE 313
Score = 33.9 bits (76), Expect = 1.7
Identities = 15/34 (44%), Positives = 18/34 (52%), Gaps = 2/34 (5%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVC 1366
C + C G TC D G F+C CP GR G +C
Sbjct: 359 CIAATCAPGSTCIDRV--GSFSCLCPPGRTGLLC 390
Score = 33.9 bits (76), Expect = 1.7
Identities = 13/29 (44%), Positives = 17/29 (58%)
Query: 1825 PCLNGASCVPREAAYVCLCPGGFSGPHCE 1853
PC G++C+ A + CLCP G G CE
Sbjct: 483 PCHPGSTCLDLLATFHCLCPPGLEGQLCE 511
Score = 33.9 bits (76), Expect = 1.7
Identities = 13/28 (46%), Positives = 15/28 (53%)
Query: 1826 CLNGASCVPREAAYVCLCPGGFSGPHCE 1853
C NG CV +Y C CP GF G C+
Sbjct: 901 CHNGGLCVDSGPSYFCHCPPGFQGSLCQ 928
Score = 33.5 bits (75), Expect = 2.2
Identities = 19/64 (29%), Positives = 24/64 (37%), Gaps = 16/64 (25%)
Query: 1824 HPCLNGASCVPREAAYVCLCPGGFSG---------------PHCEK-GLVEKSAGDVDTL 1867
H C NG +C Y CLCP ++G PHC G + SAG +
Sbjct: 283 HQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCV 342
Query: 1868 AFDG 1871
G
Sbjct: 343 CVSG 346
Score = 33.1 bits (74), Expect = 2.9
Identities = 14/39 (35%), Positives = 19/39 (48%), Gaps = 6/39 (15%)
Query: 1817 PCTRASGHPCLNGASCVPREAA---YVCLCPGGFSGPHC 1852
PC PC +G +C + ++C CP GF GP C
Sbjct: 1049 PC---HSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTC 1084
Score = 32.3 bits (72), Expect = 4.9
Identities = 15/36 (41%), Positives = 19/36 (52%), Gaps = 2/36 (5%)
Query: 1825 PCLNGASCV--PREAAYVCLCPGGFSGPHCEKGLVE 1858
PC A C P + +CLC G+SGP C + L E
Sbjct: 400 PCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDE 435
Score = 32.0 bits (71), Expect = 6.4
Identities = 14/36 (38%), Positives = 17/36 (47%), Gaps = 2/36 (5%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEK 1368
C + PC +GG C A C CP G G CE+
Sbjct: 160 CSANPCVNGGVC--LATYPQIQCHCPPGFEGHACER 193
Score = 32.0 bits (71), Expect = 6.4
Identities = 21/59 (35%), Positives = 26/59 (44%), Gaps = 5/59 (8%)
Query: 1319 PGRRPPAPQQPPKPC--DSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEKVLGAPVP 1375
PG A ++ C D PC G +C + G F C CP G+ G CE G P P
Sbjct: 184 PGFEGHACERDVNECFQDPGPCPKGTSCHNTL--GSFQCLCPVGQEGPRCELRAG-PCP 239
Score = 32.0 bits (71), Expect = 6.4
Identities = 11/31 (35%), Positives = 17/31 (54%)
Query: 1826 CLNGASCVPREAAYVCLCPGGFSGPHCEKGL 1856
C NG +C ++ C+C G+ G CE+ L
Sbjct: 326 CRNGGTCQNSAGSFHCVCVSGWGGTSCEENL 356
Score = 32.0 bits (71), Expect = 6.4
Identities = 17/50 (34%), Positives = 20/50 (40%), Gaps = 2/50 (4%)
Query: 1319 PGRRPPAPQQPPKPCDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEK 1368
PG + C S PC + C D L GF C C G G CE+
Sbjct: 503 PGLEGQLCEVETNECASAPCLNHADCHD--LLNGFQCICLPGFSGTRCEE 550
Score = 32.0 bits (71), Expect = 6.4
Identities = 12/29 (41%), Positives = 16/29 (55%)
Query: 1825 PCLNGASCVPREAAYVCLCPGGFSGPHCE 1853
PC N A+C CLCP G++G C+
Sbjct: 814 PCRNRATCQDSPQGPRCLCPTGYTGGSCQ 842
Score = 31.6 bits (70), Expect = 8.3
Identities = 11/27 (40%), Positives = 17/27 (62%)
Query: 1826 CLNGASCVPREAAYVCLCPGGFSGPHC 1852
C G++C+ R ++ CLCP G +G C
Sbjct: 364 CAPGSTCIDRVGSFSCLCPPGRTGLLC 390
>gi|119703755 laminin, beta 2 precursor [Homo sapiens]
Length = 1798
Score = 110 bits (275), Expect = 1e-23
Identities = 124/481 (25%), Positives = 172/481 (35%), Gaps = 86/481 (17%)
Query: 443 QQAECRQQRAIPSKHQGPCDQAPSPCLGVQCAFGATCAVKNGQAACECLQACSSLYDPVC 502
++ +C ++ +PSK +A +P L + + NG C+C S
Sbjct: 745 ERYQCHEEGLVPSKTSP--SEACAPLL-----ISLSTLIYNGALPCQCNPQGS------L 791
Query: 503 GSDGVTYGSACELEATACTLGREIQVARKG-------PCDRCGQCRFGAL---CEAETGR 552
S+ +G C + +GR + G C C GAL CE +G+
Sbjct: 792 SSECNPHGGQCLCKPGV--VGRRCDLCAPGYYGFGPTGCQACQCSHEGALSSLCEKTSGQ 849
Query: 553 CVCPSECVALAQPVCGSDGHTYPS-----------ECMLHVHACTHQISLHVASAGP-CE 600
C+C + L C +PS EC H AC + + G CE
Sbjct: 850 CLCRTGAFGLRCDRCQRGQWGFPSCRPCVCNGHADECNTHTGAC---LGCRDHTGGEHCE 906
Query: 601 TC-----GDAVCAFGAVCSAGQCVCPRCEHPPPGPVCGSDGVTYGSACELREAACLQQTQ 655
C GD +G C C CP GP GS + ++C E + Q
Sbjct: 907 RCIAGFHGDPRLPYGGQCRP--CPCPE------GP--GSQR-HFATSCHQDEYS---QQI 952
Query: 656 IEEARAG----PCEQAECGSGGSGSGEDGDCEQELCRQRGGI--WDEDSED---GPCVCD 706
+ RAG CE G G S G C+ LC G I D D+ D G C+
Sbjct: 953 VCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQ--LCECSGNIDPMDPDACDPHTGQCLRC 1010
Query: 707 FSCQSVPGSPVC--GSDGVTYSTECELKKARCESQRGLYVAAQGACRGPTFAPLPPVAPL 764
P C G G C + C + P P
Sbjct: 1011 LHHTEGPHCAHCKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPN 1070
Query: 765 HCAQTPYGCCQD--NITAARGVGLAGCPSACQCNPHGSYGGTCDPATGQCSCRPGVGGLR 822
+ C + N+T+ G C C+P + G TC+ TGQC CR G GG
Sbjct: 1071 VQGPSCDRCAPNFWNLTSGHGC------QPCACHPSRARGPTCNEFTGQCHCRAGFGGRT 1124
Query: 823 CDRCEPGFWNFRGIVTDGRSGCTPCSCDPQGAVRDDCEQMTGLCSCKPGVAGPKCGQCPD 882
C C+ W G+ C C CD +G C + TG CSC+PGV+G +C QC
Sbjct: 1125 CSECQELHWGDPGLQ------CHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCAR 1178
Query: 883 G 883
G
Sbjct: 1179 G 1179
Score = 106 bits (264), Expect = 3e-22
Identities = 117/432 (27%), Positives = 151/432 (34%), Gaps = 67/432 (15%)
Query: 484 GQAACECLQACSSLYDPVCGSDGVTYGSACELEATACTLGREIQVARKG--PCDRCGQCR 541
G AA QA Y C +G+ EA A L + G PC Q
Sbjct: 733 GDAAALERQATFERYQ--CHEEGLVPSKTSPSEACAPLLISLSTLIYNGALPCQCNPQGS 790
Query: 542 FGALCEAETGRCVCPSECVALAQPVCGSDGHTY-PSECMLHVHACTHQISLHVASAGPCE 600
+ C G+C+C V +C + + P+ C AC Q S A + CE
Sbjct: 791 LSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGC----QAC--QCSHEGALSSLCE 844
Query: 601 -TCGDAVCAFGAV------CSAGQCVCPRCEHPPPGPVCGSDGVTYGSACELREAACLQQ 653
T G +C GA C GQ P C C +G + C ACL
Sbjct: 845 KTSGQCLCRTGAFGLRCDRCQRGQWGFPSCR------PCVCNG--HADECNTHTGACLGC 896
Query: 654 TQIEEARAGPCEQAECG-SGGSGSGEDGDCEQELCRQRGGI---------WDEDSEDGPC 703
+ CE+ G G G C C + G DE S+ C
Sbjct: 897 R--DHTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVC 954
Query: 704 VC-----DFSCQS-VPG--SPVCGSDGVTYSTECE-----LKKARCESQRGLYVAAQGAC 750
C C++ PG G EC + C+ G +
Sbjct: 955 HCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHT 1014
Query: 751 RGPTFAPLPPVAPLHCAQTPYGCCQDNITAARGVGLAGCPSACQCNPHGSYGGTCDPATG 810
GP A P A+ C N+ G CPS QC+ CDP++G
Sbjct: 1015 EGPHCAHCKPGFHGQAARQSCHRCTCNLL---GTNPQQCPSPDQCH--------CDPSSG 1063
Query: 811 QCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDPQGAVRDDCEQMTGLCSCKP 870
QC C P V G CDRC P FWN +T G GC PC+C P A C + TG C C+
Sbjct: 1064 QCPCLPNVQGPSCDRCAPNFWN----LTSGH-GCQPCACHPSRARGPTCNEFTGQCHCRA 1118
Query: 871 GVAGPKCGQCPD 882
G G C +C +
Sbjct: 1119 GFGGRTCSECQE 1130
Score = 103 bits (258), Expect = 1e-21
Identities = 56/163 (34%), Positives = 75/163 (46%), Gaps = 26/163 (15%)
Query: 793 CQCNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDPQ 852
CQCNP GS C+P GQC C+PGV G RCD C PG++ F G +GC C C +
Sbjct: 783 CQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGF------GPTGCQACQCSHE 836
Query: 853 GAVRDDCEQMTGLCSCKPGVAGPKCGQCPDGR----ALGPAGCEADASAPATCAEMRCEF 908
GA+ CE+ +G C C+ G G +C +C G+ + P C A E
Sbjct: 837 GALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFPSCRPCVCNGHAD------ECNTHT 890
Query: 909 GA--RCVEESGSAHCVCPMLTCPEANATKVCGSDGVTYGNECQ 949
GA C + +G HC E G + YG +C+
Sbjct: 891 GACLGCRDHTGGEHC--------ERCIAGFHGDPRLPYGGQCR 925
Score = 87.4 bits (215), Expect = 1e-16
Identities = 83/311 (26%), Positives = 113/311 (36%), Gaps = 76/311 (24%)
Query: 616 GQCVC----PRCEHPPPGPVCGSDGVTYGSAC---ELREAACLQQTQI---------EEA 659
G C C C P PG ++G+ +G+ R C Q E+
Sbjct: 281 GNCFCYGHASECA-PAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDG 339
Query: 660 RAGPCEQAEC---------------GSGGSGSGEDGDCEQ-------ELCRQRGGIWDED 697
+ C + EC SG G C+ ELCR + +
Sbjct: 340 HSHACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPF--FYRDP 397
Query: 698 SED--GPCVCDFSCQSVPGSPVCGSDGVTYSTECELKKARCESQRGLYVA-AQGACRGPT 754
++D P VC +S P+ DG RC+S + G CR
Sbjct: 398 TKDLRDPAVC----RSCDCDPMGSQDG-----------GRCDSHDDPALGLVSGQCRCKE 442
Query: 755 FAPLPPVAPLHCAQTPYGCCQDNITAARGVGLAGCPSACQCNPHGSYGGT--CDPATGQC 812
V C Q C+D GC CQCN G+ G+ CDP +G C
Sbjct: 443 H-----VVGTRCQQ-----CRDGFFGLSISDRLGC-RRCQCNARGTVPGSTPCDPNSGSC 491
Query: 813 SCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDPQGAVRDDCEQMTGLCSCKPGV 872
C+ V G CDRC PG W ++ GC PC CD GA+ C++ TG C C+ +
Sbjct: 492 YCKRLVTGRGCDRCLPGHWG----LSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHM 547
Query: 873 AGPKCGQCPDG 883
G +C Q G
Sbjct: 548 VGRRCEQVQPG 558
Score = 85.5 bits (210), Expect = 5e-16
Identities = 49/145 (33%), Positives = 61/145 (42%), Gaps = 16/145 (11%)
Query: 783 GVGLAGCPSACQCNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRS 842
G G GC ACQC+ G+ C+ +GQC CR G GLRCDRC+ G W F
Sbjct: 822 GFGPTGC-QACQCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGF--------P 872
Query: 843 GCTPCSCDPQGAVRDDCEQMTGLC-SCKPGVAGPKCGQCPDGRALGPAGCEADASAPATC 901
C PC C+ D+C TG C C+ G C +C G P P C
Sbjct: 873 SCRPCVCNGHA---DECNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPC 929
Query: 902 AE---MRCEFGARCVEESGSAHCVC 923
E + F C ++ S VC
Sbjct: 930 PEGPGSQRHFATSCHQDEYSQQIVC 954
Score = 63.5 bits (153), Expect = 2e-09
Identities = 37/120 (30%), Positives = 54/120 (45%), Gaps = 10/120 (8%)
Query: 842 SGCTPCSCDPQGAVRDDCEQMTGLCSCKPGVAGPKCGQCPDG-RALGPAGCEADASAPAT 900
+G PC C+PQG++ +C G C CKPGV G +C C G GP GC+A +
Sbjct: 778 NGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGCQACQCSHEG 837
Query: 901 CAEMRCE-FGARCVEESGSAHCVCPMLTCPEAN----ATKVCGSDGVTYGNECQLKTIAC 955
CE +C+ +G+ C C + + C +G + +EC T AC
Sbjct: 838 ALSSLCEKTSGQCLCRTGAFGLRCD--RCQRGQWGFPSCRPCVCNG--HADECNTHTGAC 893
Score = 57.8 bits (138), Expect = 1e-07
Identities = 72/302 (23%), Positives = 107/302 (35%), Gaps = 70/302 (23%)
Query: 551 GRCVCPSECVALAQPVC-----------GSDGHTYPS---ECMLHVHACTHQISLHVASA 596
G C+C L C DGH++ EC H H+C +++++AS
Sbjct: 308 GACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASG 367
Query: 597 GPCETCGDAVCAFGAVCSAGQCVCPRCEHPPPGPVCGSDGVTYGSACELREAACLQQTQI 656
S G VC C+H T G CEL +
Sbjct: 368 N---------------VSGG--VCDGCQHN-----------TAGRHCELCRPFFYRDPTK 399
Query: 657 EEARAGPCEQAECGSGGSGSGEDGDCEQELCRQRGGIWDEDSEDGPCVCDFSCQSVPGSP 716
+ C +C GS G G C+ G + G C C + V G+
Sbjct: 400 DLRDPAVCRSCDCDPMGSQDG--GRCDSHDDPALGLV------SGQCRCK---EHVVGTR 448
Query: 717 V--C--GSDGVTYSTECELKKARCESQRGLYVAAQGACRGPTFAPLPPVAPLHCAQTPYG 772
C G G++ S ++ +C A+G G T P +C + G
Sbjct: 449 CQQCRDGFFGLSISDRLGCRRCQCN--------ARGTVPGSTPCD-PNSGSCYCKRLVTG 499
Query: 773 C-CQDNITAARGVG--LAGCPSACQCNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPG 829
C + G+ L GC C C+ G+ CD TGQC CR + G RC++ +PG
Sbjct: 500 RGCDRCLPGHWGLSHDLLGC-RPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPG 558
Query: 830 FW 831
++
Sbjct: 559 YF 560
Score = 35.4 bits (80), Expect = 0.58
Identities = 26/78 (33%), Positives = 32/78 (41%), Gaps = 5/78 (6%)
Query: 1549 GDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCH-GAAPCRVLP 1607
G PC PN G C+ L GR +C PG G + + C+P C G A
Sbjct: 480 GSTPCDPNS--GSCYCKRLVTGRGCDRCLPGHWG--LSHDLLGCRPCDCDVGGALDPQCD 535
Query: 1608 EGGAQCECPLGREGTFCQ 1625
EG QC C G C+
Sbjct: 536 EGTGQCHCRQHMVGRRCE 553
>gi|148886692 FAT tumor suppressor homolog 3 [Homo sapiens]
Length = 4557
Score = 110 bits (274), Expect = 2e-23
Identities = 87/310 (28%), Positives = 134/310 (43%), Gaps = 27/310 (8%)
Query: 1332 PCDSQPCFHGGTCQDW-ALGGGFTCSCPAGRGGAVCEKVLGAPVPAFEGRSFLAFPTLR- 1389
PC +PC C + A F C CP G+ G + G +F G S++ +
Sbjct: 3798 PCVEKPCPGDMQCVSYEASRRPFLCQCPPGKLG----ECSGHTSLSFAGNSYIKYRLSEN 3853
Query: 1390 -AYHTLRLALEFRALEPQGLLLYNGNARGKDFLALALLDGRVQLRFDTGSGPAVL-TSAV 1447
+LAL R L+ G+++Y R + L ++DG++ + D GSGP +L S
Sbjct: 3854 SKEEDFKLALRLRTLQSNGIIMYT---RANPCIILKIVDGKLWFQLDCGSGPGILGISGR 3910
Query: 1448 PVEPGQWHR--LELSRHWRRGTLSVDGETPVLGESPSGTDGLNLDTDLFVGGVPEDQAAV 1505
V G WH LEL+R++ +LS+D +P L+ ++ ++ G + +
Sbjct: 3911 AVNDGSWHSVFLELNRNFT--SLSLDDSYVERRRAPLYFQTLSTESSIYFGALVQADNIR 3968
Query: 1506 ALERTFVG---AGLRGCIRLLDVNNQRLELGIGPGAATRGSGVGE----CGDHP--CLPN 1556
+L T V +G +GC+ + +NN L L + G+ E C +P C +
Sbjct: 3969 SLTDTRVTQVLSGFQGCLDSVILNNNELPLQNKRSSFAEVVGLTELKLGCVLYPDACKRS 4028
Query: 1557 PCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGA-QCEC 1615
PC G C L +G + C C G C E + C PNPC C P G C C
Sbjct: 4029 PCQHGGSCTGLPSGGYQCTCLSQFTGRNCESEITACFPNPCRNGGSCD--PIGNTFICNC 4086
Query: 1616 PLGREGTFCQ 1625
G G C+
Sbjct: 4087 KAGLTGVTCE 4096
Score = 70.5 bits (171), Expect = 2e-11
Identities = 85/372 (22%), Positives = 129/372 (34%), Gaps = 109/372 (29%)
Query: 1540 TRGSGVGECGDHPCLPNPCHGGAPCQNLEAGR--FHCQCPPGRVGPTCADEKSPCQPNPC 1597
T G+ + PC+ PC G C + EA R F CQCPPG++G
Sbjct: 3786 TCNGGLCPGSNDPCVEKPCPGDMQCVSYEASRRPFLCQCPPGKLG--------------- 3830
Query: 1598 HGAAPCRVLPEGGAQCECPLGREGTFCQTASGQDGSGPFLADFNGFSHLELRGLHTFARD 1657
EC SG F G S+++ R L +++
Sbjct: 3831 ----------------EC-----------------SGHTSLSFAGNSYIKYR-LSENSKE 3856
Query: 1658 LGEKMALEVVFLARGPSGLLLYNGQKTDGKGDFVSLALRDRRLEFRYDLGKGAAVIR-SR 1716
K+AL + L +G+++Y + L + D +L F+ D G G ++ S
Sbjct: 3857 EDFKLALRLRTLQ--SNGIIMYT-----RANPCIILKIVDGKLWFQLDCGSGPGILGISG 3909
Query: 1717 EPVTLGAWTRVSLERNGRKGALRVGDGPRVLGESPVPHTVLNLKEPLYVGGAPDFSKL-- 1774
V G+W V LE N +L + D +P+ L+ + +Y G +
Sbjct: 3910 RAVNDGSWHSVFLELNRNFTSLSLDDSYVERRRAPLYFQTLSTESSIYFGALVQADNIRS 3969
Query: 1775 ---ARAAAVSSGFDGAIQLVSLGGRQL-----------------------LTPEHVLRQ- 1807
R V SGF G + V L +L L P+ R
Sbjct: 3970 LTDTRVTQVLSGFQGCLDSVILNNNELPLQNKRSSFAEVVGLTELKLGCVLYPDACKRSP 4029
Query: 1808 -----------------VDVTSFAGHPC----TRASGHPCLNGASCVPREAAYVCLCPGG 1846
++ F G C T +PC NG SC P ++C C G
Sbjct: 4030 CQHGGSCTGLPSGGYQCTCLSQFTGRNCESEITACFPNPCRNGGSCDPIGNTFICNCKAG 4089
Query: 1847 FSGPHCEKGLVE 1858
+G CE+ + E
Sbjct: 4090 LTGVTCEEDINE 4101
Score = 58.2 bits (139), Expect = 8e-08
Identities = 57/221 (25%), Positives = 90/221 (40%), Gaps = 28/221 (12%)
Query: 1817 PCTRASGHPCLNGASCVPREAA---YVCLCPGGFSGPHCEKGLVEKSAGDVDTLAFDGRT 1873
PC PC CV EA+ ++C CP G G +L+F G +
Sbjct: 3798 PCVEK---PCPGDMQCVSYEASRRPFLCQCPPGKLG----------ECSGHTSLSFAGNS 3844
Query: 1874 FVEYLNAVTESEKALQSNHFELSLRTEATQGLVLWSGKATERADYVALAIVDGHLQLSYN 1933
+++Y + E+ + L LRT + G++++ T + L IVDG L +
Sbjct: 3845 YIKYRLSENSKEEDFK---LALRLRTLQSNGIIMY----TRANPCIILKIVDGKLWFQLD 3897
Query: 1934 LGSQPVVLR-STVPVNTNRWLRVVAHREQREGSLQVGNEAPVTGSSPLGATQLDTDGALW 1992
GS P +L S VN W V + SL + + +PL L T+ +++
Sbjct: 3898 CGSGPGILGISGRAVNDGSWHSVFLELNRNFTSLSLDDSYVERRRAPLYFQTLSTESSIY 3957
Query: 1993 LGGLPELPVGPALPKAYGT----GFVGCLRDVVVGRHPLHL 2029
G L + +L T GF GCL V++ + L L
Sbjct: 3958 FGALVQADNIRSLTDTRVTQVLSGFQGCLDSVILNNNELPL 3998
Score = 43.1 bits (100), Expect = 0.003
Identities = 44/150 (29%), Positives = 55/150 (36%), Gaps = 56/150 (37%)
Query: 788 GC---PSACQCNPHGSYGGTCD--PATG-QCSCRPGVGGLRCDR----CEPGFWNFRGIV 837
GC P AC+ +P +GG+C P+ G QC+C G C+ C P
Sbjct: 4017 GCVLYPDACKRSPC-QHGGSCTGLPSGGYQCTCLSQFTGRNCESEITACFPN-------- 4067
Query: 838 TDGRSGCTPC----SCDPQGAVRDDCEQMTGLCSCKPGVAGPKCGQCPDGRALGPAGCEA 893
PC SCDP G T +C+CK G+ G CE
Sbjct: 4068 --------PCRNGGSCDPIGN--------TFICNCKAGLTG--------------VTCEE 4097
Query: 894 DASAPATCAEMRCEFGARCVEESGSAHCVC 923
D + C CE G CV GS C C
Sbjct: 4098 DINE---CEREECENGGSCVNVFGSFLCNC 4124
Score = 40.4 bits (93), Expect = 0.018
Identities = 29/95 (30%), Positives = 43/95 (45%), Gaps = 23/95 (24%)
Query: 791 SACQCNPHGSYGGTCDPA--TGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCS 848
+AC NP + GG+CDP T C+C+ G+ G+ C+ + + C
Sbjct: 4062 TACFPNPCRN-GGSCDPIGNTFICNCKAGLTGVTCE--------------EDINECEREE 4106
Query: 849 CDPQGAVRDDCEQMTG--LCSCKPGVAGPKCGQCP 881
C+ G+ C + G LC+C PG G CG P
Sbjct: 4107 CENGGS----CVNVFGSFLCNCTPGYVGQYCGLRP 4137
Score = 36.6 bits (83), Expect = 0.26
Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 1/46 (2%)
Query: 1330 PKPCDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEKVLGAPVP 1375
P C PC HGG+C GG+ C+C + G CE + A P
Sbjct: 4022 PDACKRSPCQHGGSCTGLP-SGGYQCTCLSQFTGRNCESEITACFP 4066
Score = 36.6 bits (83), Expect = 0.26
Identities = 15/36 (41%), Positives = 20/36 (55%), Gaps = 2/36 (5%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEK 1368
C PC +GG+C +G F C+C AG G CE+
Sbjct: 4064 CFPNPCRNGGSCDP--IGNTFICNCKAGLTGVTCEE 4097
>gi|12383051 transmembrane protein with EGF-like and two
follistatin-like domains 2 [Homo sapiens]
Length = 374
Score = 109 bits (272), Expect = 3e-23
Identities = 87/300 (29%), Positives = 122/300 (40%), Gaps = 19/300 (6%)
Query: 539 QCRFGALCEAETGRCVCPSECVALAQPVCGSDGHTYPSECMLHVHACTHQISLHVASAGP 598
QC LCE + P + +A+PV + T S+C S +
Sbjct: 9 QCSSWTLCEGFCWLLLLPVMLLIVARPVKLAAFPTSLSDCQTPTG---WNCSGYDDREND 65
Query: 599 CETCGDAVCAFGAVC----SAGQCVCPRCEHPPPGPVCGSDGVTYGSACELREAACLQQT 654
C C F C CVC + PVCGS+G +Y + C LR+AAC QQ+
Sbjct: 66 LFLCDTNTCKFDGECLRIGDTVTCVCQFKCNNDYVPVCGSNGESYQNECYLRQAACKQQS 125
Query: 655 QIEEARAGPCEQAECGSGGS-----GSGEDGDCEQELCR--QRGGIWDEDSEDGPCVCDF 707
+I G C + GSG GSGE E C Q G DED+ED CVC+
Sbjct: 126 EILVVSEGSCA-TDAGSGSGDGVHEGSGETSQKETSTCDICQFGAECDEDAEDVWCVCNI 184
Query: 708 SCQSVPGSPVCGSDGVTYSTECELKKARCESQRGLYVAAQGACRGPTFAPLPPVAPLHCA 767
C +P+C SDG +Y C++K+A C+ Q + V + G C+ T H A
Sbjct: 185 DCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNT-TTTTKSEDGHYA 243
Query: 768 QTPYGCCQDNITAARGVGLAGCPSACQ--CNPHGSYGGTCDPATGQCSCRPGVGGLRCDR 825
+T Y + + + CP C HG + + C C G G C++
Sbjct: 244 RTDYAENANKLEESAREHHIPCPEHYNGFC-MHGKCEHSINMQEPSCRCDAGYTGQHCEK 302
Score = 81.3 bits (199), Expect = 9e-15
Identities = 47/155 (30%), Positives = 70/155 (45%), Gaps = 20/155 (12%)
Query: 399 CRFNAVCLSRRGRPRCSCDRVTCDGAYRPVCAQDGRTYDSDCWRQQAECRQQRAIPSKHQ 458
C+F+ CL C C + C+ Y PVC +G +Y ++C+ +QA C+QQ I +
Sbjct: 74 CKFDGECLRIGDTVTCVC-QFKCNNDYVPVCGSNGESYQNECYLRQAACKQQSEILVVSE 132
Query: 459 GPC--DQAPSPCLGVQ----------------CAFGATCAVKNGQAACECLQACSSL-YD 499
G C D GV C FGA C C C CS ++
Sbjct: 133 GSCATDAGSGSGDGVHEGSGETSQKETSTCDICQFGAECDEDAEDVWCVCNIDCSQTNFN 192
Query: 500 PVCGSDGVTYGSACELEATACTLGREIQVARKGPC 534
P+C SDG +Y +AC+++ +C +I+V G C
Sbjct: 193 PLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRC 227
Score = 80.5 bits (197), Expect = 2e-14
Identities = 48/155 (30%), Positives = 64/155 (41%), Gaps = 27/155 (17%)
Query: 473 CAFGATCAVKNGQAACECLQACSSLYDPVCGSDGVTYGSACELEATACTLGREIQVARKG 532
C F C C C C++ Y PVCGS+G +Y + C L AC EI V +G
Sbjct: 74 CKFDGECLRIGDTVTCVCQFKCNNDYVPVCGSNGESYQNECYLRQAACKQQSEILVVSEG 133
Query: 533 PC------------------------DRCGQCRFGALC--EAETGRCVCPSECVAL-AQP 565
C C C+FGA C +AE CVC +C P
Sbjct: 134 SCATDAGSGSGDGVHEGSGETSQKETSTCDICQFGAECDEDAEDVWCVCNIDCSQTNFNP 193
Query: 566 VCGSDGHTYPSECMLHVHACTHQISLHVASAGPCE 600
+C SDG +Y + C + +C Q + V S G C+
Sbjct: 194 LCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQ 228
Score = 78.2 bits (191), Expect = 8e-14
Identities = 45/143 (31%), Positives = 64/143 (44%), Gaps = 22/143 (15%)
Query: 194 SCVCKKSPCPSVVAPVCGSDASTYSNECELQRAQCSQQRRIRLLSRGPC----------- 242
+CVC+ C + PVCGS+ +Y NEC L++A C QQ I ++S G C
Sbjct: 88 TCVCQFK-CNNDYVPVCGSNGESYQNECYLRQAACKQQSEILVVSEGSCATDAGSGSGDG 146
Query: 243 ---GSRDPCSNVT-----CSFGSTCARSADGLTASCLCPATCRGAPEGTVCGSDGADYPG 294
GS + T C FG+ C A+ + C+C C +C SDG Y
Sbjct: 147 VHEGSGETSQKETSTCDICQFGAECDEDAEDVW--CVCNIDCSQTNFNPLCASDGKSYDN 204
Query: 295 ECQLLRRACARQENVFKKFDGPC 317
CQ+ +C +QE + G C
Sbjct: 205 ACQIKEASCQKQEKIEVMSLGRC 227
Score = 67.4 bits (163), Expect = 1e-10
Identities = 36/119 (30%), Positives = 56/119 (47%), Gaps = 4/119 (3%)
Query: 859 CEQMTGLCSCKPGVAGPKCGQCPDGRALGPAGCEADASAPATCAEMRCEFGARCVEESGS 918
C+Q + + G G G + E +TC C+FGA C E++
Sbjct: 121 CKQQSEILVVSEGSCATDAGS-GSGDGVHEGSGETSQKETSTCDI--CQFGAECDEDAED 177
Query: 919 AHCVCPMLTCPEANATKVCGSDGVTYGNECQLKTIACRQGLQISIQSLGPCQEAVAPST 977
CVC + C + N +C SDG +Y N CQ+K +C++ +I + SLG CQ+ +T
Sbjct: 178 VWCVCN-IDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTT 235
Score = 58.2 bits (139), Expect = 8e-08
Identities = 33/133 (24%), Positives = 54/133 (40%), Gaps = 20/133 (15%)
Query: 349 CPARQAPVCGDDGVTYENDCVMGRSGAARGLLLQKVRSGQC------------------- 389
C PVCG +G +Y+N+C + ++ + + V G C
Sbjct: 95 CNNDYVPVCGSNGESYQNECYLRQAACKQQSEILVVSEGSCATDAGSGSGDGVHEGSGET 154
Query: 390 -QGRDQCPEPCRFNAVCLSRRGRPRCSCDRVTCDGAYRPVCAQDGRTYDSDCWRQQAECR 448
Q + C+F A C C C+ + P+CA DG++YD+ C ++A C+
Sbjct: 155 SQKETSTCDICQFGAECDEDAEDVWCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQ 214
Query: 449 QQRAIPSKHQGPC 461
+Q I G C
Sbjct: 215 KQEKIEVMSLGRC 227
Score = 55.1 bits (131), Expect = 7e-07
Identities = 24/67 (35%), Positives = 37/67 (55%), Gaps = 3/67 (4%)
Query: 176 LCGFGAVCEPNAEGPGRASCVCKKSPCPSVVAPVCGSDASTYSNECELQRAQCSQQRRIR 235
+C FGA C+ +AE CVC + P+C SD +Y N C+++ A C +Q +I
Sbjct: 164 ICQFGAECDEDAED---VWCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIE 220
Query: 236 LLSRGPC 242
++S G C
Sbjct: 221 VMSLGRC 227
Score = 50.1 bits (118), Expect = 2e-05
Identities = 25/69 (36%), Positives = 35/69 (50%), Gaps = 2/69 (2%)
Query: 901 CAEMRCEFGARCVEESGSAHCVCPMLTCPEANATKVCGSDGVTYGNECQLKTIACRQGLQ 960
C C+F C+ + CVC C + VCGS+G +Y NEC L+ AC+Q +
Sbjct: 69 CDTNTCKFDGECLRIGDTVTCVC-QFKCNN-DYVPVCGSNGESYQNECYLRQAACKQQSE 126
Query: 961 ISIQSLGPC 969
I + S G C
Sbjct: 127 ILVVSEGSC 135
>gi|24041035 notch 2 preproprotein [Homo sapiens]
Length = 2471
Score = 109 bits (272), Expect = 3e-23
Identities = 193/877 (22%), Positives = 272/877 (31%), Gaps = 209/877 (23%)
Query: 172 CRGMLCGFGAVCEPNAEGPGRASCV-----CKKSPC------PSVVAPVCGSDASTYSNE 220
C + GF +C EGP SC C +PC + C DA
Sbjct: 697 CINGVNGFRCICP---EGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGIN 753
Query: 221 CELQRAQCSQQRRIRLLSRGPCGSRDPCSNVTCSFGSTCARSADGLTAS----------C 270
CE+ + +C PC + C N+ + TC + G C
Sbjct: 754 CEVDKNECLSN---------PCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPC 804
Query: 271 LCPATCRGAPEGTVCGSDGADYPGE-CQLLRRACARQENVFKKFDGPCDPCQGALPDP-- 327
L TC G C Y G+ CQ + C+ PC+ P
Sbjct: 805 LNQGTCFDDISGYTCHCV-LPYTGKNCQTVLAPCS---------PNPCENAAVCKESPNF 854
Query: 328 -SRSCRVNPRTRRPEMLLRPESC---PARQAPVCGDDGVTYENDCVMGRSGAARGLLLQK 383
S +C P + + + C P +C + +Y +C G SG +
Sbjct: 855 ESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDD 914
Query: 384 VRSGQCQGRDQCPEPCR-FNAVCLSRRGRPRCSCDRVTCDGAYRPVCAQDGRTYDSDCWR 442
+ CQ C + F+ +CL +C D C C G D +
Sbjct: 915 CLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNEC---LSEPCKNGGTCSD---YV 968
Query: 443 QQAECRQQRAIPSKHQGPCDQAPSPCLGVQCAFGATCAVKNGQAACECLQACSSLYDPVC 502
C+ Q H C+ + C C G TC +C C PV
Sbjct: 969 NSYTCKCQAGFDGVH---CENNINECTESSCFNGGTCVDGINSFSCLC---------PV- 1015
Query: 503 GSDGVTYGSACELEATACTLGREIQVARKGPCDRCGQCRFGALCEAETGRCVCPSECVAL 562
G T GS C E C+ PC G C G T RC CP
Sbjct: 1016 ---GFT-GSFCLHEINECS---------SHPCLNEGTCVDGL----GTYRCSCPL----- 1053
Query: 563 AQPVCGSDGHTYPSECMLHVHACTHQISLHVASAGPCETCGDAVCAFGAVCSAGQCVCPR 622
G+T C V+ C S PC+ G V + QC+CP
Sbjct: 1054 --------GYT-GKNCQTLVNLC---------SRSPCKNKGTCV----QKKAESQCLCPS 1091
Query: 623 CEHPPPGPVCGSDGVTYGSACELREAACLQQTQIEEA--RAGPCEQAECGSGGSGSGEDG 680
G C V+ A R Q AG +C G +GS
Sbjct: 1092 GW---AGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSY--- 1145
Query: 681 DCEQELCRQRGGIWDEDSEDGPCVCDFSCQSVPGSPVCGSDGVTYSTECELKKARCESQR 740
CE++L ++ PC +C G C CE + C++Q
Sbjct: 1146 -CEEQL---------DECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQ- 1194
Query: 741 GLYVAAQGACR-GPTFAPLPPVAPLHCAQTPYGC-CQDNITAARGVGLAGCPSACQCNPH 798
C+ G T L C G C++NI C PH
Sbjct: 1195 --------PCQNGGTCIDLVNHFKCSCPPGTRGLLCEENI------------DDCARGPH 1234
Query: 799 GSYGGTCDPATG--QCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDPQGAVR 856
GG C G C C PG G RC+ G + + C C +G++
Sbjct: 1235 CLNGGQCMDRIGGYSCRCLPGFAGERCE----------GDINE----CLSNPCSSEGSL- 1279
Query: 857 DDCEQMTG--LCSCKPGVAGPKCGQ----CPDGRALGPAGCEADASAP------------ 898
DC Q+T LC C+ G C CP L C ++ P
Sbjct: 1280 -DCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFS 1338
Query: 899 -----ATCAEMRCEFGARCVEESGSAHCVCPMLTCPEANATKVCGSDGVTYGNECQLKTI 953
++C +++C G +CV + C CP E+ C S +G C +
Sbjct: 1339 GARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESG----CASSPCQHGGSCHPQ-- 1392
Query: 954 ACRQGLQISIQSLGP-----CQEAVAPSTHPTSASVT 985
RQ S Q P C+ AP + P + ++
Sbjct: 1393 --RQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLS 1427
Score = 90.1 bits (222), Expect = 2e-17
Identities = 189/905 (20%), Positives = 267/905 (29%), Gaps = 264/905 (29%)
Query: 170 DACRGMLCGFGAVCEPNAEGPGRASCVCKKSPCPSVVAPVCGSDASTYSNECELQ----- 224
DAC C G+ C A + SC C + G T NEC++
Sbjct: 146 DACLSHPCANGSTCTTVAN---QFSCKC--------LTGFTGQKCETDVNECDIPGHCQH 194
Query: 225 -----------RAQCSQQRRIRLLSRGPCGSRD-PCSNVTCSFGSTCARSADGLTASCLC 272
+ QC Q + C S PC+ C G TC ++ D T C
Sbjct: 195 GGTCLNLPGSYQCQCPQG-----FTGQYCDSLYVPCAPSPCVNGGTCRQTGD-FTFEC-- 246
Query: 273 PATCRGAPEGTVCGSDGADYPGECQLLRRACARQENVFKKFDGPCDPCQGALPDPSRSCR 332
C EG+ C + D P C N + C+ + C
Sbjct: 247 --NCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYN--------CRCPPQWTGQFCT 296
Query: 333 VNPRTRRPEMLLRPESCPARQAPVCGDDGVTYENDCVMGRSG---------------AAR 377
+ E LL+P +C + C + Y CV G SG
Sbjct: 297 EDV----DECLLQPNAC--QNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPG 350
Query: 378 GLLLQKVRSGQCQGRDQCPEP-----CRFNAVCLSRRGRPRCSCDRVTCDGAYRPVCAQD 432
+ +V S C CPE C + C+S CD +G Y C Q
Sbjct: 351 STCIDRVASFSC----MCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQG 406
Query: 433 GRTYDSDCWRQQAECRQQRAIPSKHQGP--------------------CDQAPSPCLGVQ 472
+ +DC EC + P +H G C+ + C
Sbjct: 407 YK--GADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDP 464
Query: 473 CAFGATCAVKNGQAACECLQACSSLYDPVCGSDGVTYGSACELEATACTLGREIQVARKG 532
C ATC K G C C+ ++ CELE C +
Sbjct: 465 CQNDATCLDKIGGFTCLCMPGFKGVH--------------CELEINEC---------QSN 501
Query: 533 PCDRCGQC-----RFGALCEAETGRCVCP------SECVALAQPVCGSDGHTYPSECMLH 581
PC GQC RF LC VC S L C + Y +C
Sbjct: 502 PCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATG 561
Query: 582 VHACTHQISLHVASAGPCE--TCGDAVCAFGAVCSAGQCVCPRCEHPPPGPVCGSDGV-- 637
+ ++ PC C D + ++ +C+ G G +C SD +
Sbjct: 562 FTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYM----------GAIC-SDQIDE 610
Query: 638 TYGSACELREAACLQQTQIEEARAGPCEQAECGSGGSGSGEDGDCEQELCRQRGGIWDED 697
Y S C L + C+ Q C G SG +CE I +D
Sbjct: 611 CYSSPC-LNDGRCIDLVN--------GYQCNCQPGTSGV----NCE---------INFDD 648
Query: 698 SEDGPCVCDFSCQSVPGSPVCGSDGVTYSTECELKKARCESQRGLYVAAQGACR-GPT-- 754
PC+ + S G T C + C A CR G T
Sbjct: 649 CASNPCIHGICMDGINRYSCVCSPGFT-GQRCNIDIDEC---------ASNPCRKGATCI 698
Query: 755 -----FAPLPPVAPLH---------CAQTP--YGCCQDNITAAR--------GVGLAGCP 790
F + P P H C P +G C ++ + G+
Sbjct: 699 NGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDK 758
Query: 791 SACQCNPHGSYGGTCDPATG--QCSCRPGVGGLRC----DRCEPGFWNFRGIVTDGRSG- 843
+ C NP + GGTCD +C+C+ G G C D C +G D SG
Sbjct: 759 NECLSNPCQN-GGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGY 817
Query: 844 -------------------CTPCSCDPQGAVRDDCEQMTGLCSCKPGVAGPKCG------ 878
C+P C+ ++ + C C PG G +C
Sbjct: 818 TCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDEC 877
Query: 879 --------------------QCPDGRALGPAGCEADASAPATCAEMRCEFGARCVEESGS 918
+CP G CE D C C+ G C++ +
Sbjct: 878 ISKPCMNHGLCHNTQGSYMCECPPG--FSGMDCEEDID---DCLANPCQNGGSCMDGVNT 932
Query: 919 AHCVC 923
C+C
Sbjct: 933 FSCLC 937
Score = 85.9 bits (211), Expect = 4e-16
Identities = 193/809 (23%), Positives = 251/809 (31%), Gaps = 219/809 (27%)
Query: 170 DACRGMLCGFGAVCEPNAEGPGRASCVCKKSPCPSVVAPVCGSDAS-TYSNECELQRAQC 228
D C C G C A G+A+C C G D + S+ C + R C
Sbjct: 66 DPCEKNRCQNGGTCVAQAM-LGKATCRCASG--------FTGEDCQYSTSHPCFVSRP-C 115
Query: 229 SQQRRIRLLSRGP-------------CGSRDPCSNVTCSFGSTCARSADGLTASCLCPAT 275
+LSR C D C + C+ GSTC A+ + CL T
Sbjct: 116 LNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFT 175
Query: 276 CRGAPEGTVCGSD--GADYPGECQ----LLRRACARQENVFKKFDGP-CD----PCQGAL 324
G C +D D PG CQ L + Q + F G CD PC
Sbjct: 176 ------GQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPC---A 226
Query: 325 PDPSRSCRVNPRTRRPEMLLRPESCPARQAPVCGDDGVTYENDCVMGRSGAARGLLLQKV 384
P P VN T R GD T+E +C+ G G+
Sbjct: 227 PSPC----VNGGTCRQ----------------TGD--FTFECNCLPGFEGST-------- 256
Query: 385 RSGQCQGR-DQCP-EPCRFNAVCLSRRGRPRCSCDRVTCDGAYRPVCAQDGRTYDSDCWR 442
C+ D CP C+ VC+ C C P T D D
Sbjct: 257 ----CERNIDDCPNHRCQNGGVCVDGVNTYNCRCP---------PQWTGQFCTEDVD--- 300
Query: 443 QQAECRQQRAIPSKHQGPCDQAPSPCLGVQCAFGATCAVKNGQAACECLQA-----CSSL 497
EC Q P+ C G TCA +NG C C+ CS
Sbjct: 301 ---ECLLQ--------------PNACQN-----GGTCANRNGGYGCVCVNGWSGDDCSEN 338
Query: 498 YDPVCGSDGVTYGSACELEATA-----CTLGREIQVARKGPCDRCGQCRFGALCEAE--T 550
D C T GS C ++ A C G+ + C GALC+
Sbjct: 339 IDD-CAFASCTPGSTC-IDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLN 396
Query: 551 GR--CVCPSECVALAQPVCGSDGHTYPSECMLHVHACTHQISLHVASAGPCETCGDAVCA 608
G+ C CP G G ++C V C +A++ PCE G V
Sbjct: 397 GQYICTCPQ----------GYKG----ADCTEDVDECA------MANSNPCEHAGKCVNT 436
Query: 609 FGAVCSAGQCVCPRCEHPPPGPVCGSD-GVTYGSACELREAACLQQTQIEEARAGPCEQA 667
GA C C + GP C D + C+ +A CL ++ C
Sbjct: 437 DGAF----HCECLK---GYAGPRCEMDINECHSDPCQ-NDATCL-----DKIGGFTCLCM 483
Query: 668 ECGSGGSGSGEDGDCEQELCRQRGGIWDEDSEDGPCVCDFSCQSVPG--SPVCGSDGVTY 725
G E +C+ C G D+ V F C PG PVC D
Sbjct: 484 PGFKGVHCELEINECQSNPCVNNGQCVDK-------VNRFQCLCPPGFTGPVCQIDIDDC 536
Query: 726 STECELKKARCESQRGLYVAAQGACRGPTFAPLPPVAPLHCAQTP--YGCCQDNITAARG 783
S+ L A+C Y + C L +C P +G CQD I +
Sbjct: 537 SSTPCLNGAKCIDHPNGY---ECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDS--- 590
Query: 784 VGLAGCPSACQCNPHGSYGGTCDPATGQCSCRPGVGGLRC--------DRCEPGFWNFRG 835
C CNP G G C +C P + RC C+PG
Sbjct: 591 -------YTCICNP-GYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNC 642
Query: 836 IVTDGRSGCTPCSCDPQGAVRDDCEQMTGLCSCKPGVAGPKCGQCPDGRALGPAGCEADA 895
+ PC G D + + C C PG G +C D
Sbjct: 643 EINFDDCASNPCI---HGICMDGINRYS--CVCSPGFTGQRCNIDID------------- 684
Query: 896 SAPATCAEMRCEFGARCVEESGSAHCVCP 924
CA C GA C+ C+CP
Sbjct: 685 ----ECASNPCRKGATCINGVNGFRCICP 709
Score = 84.7 bits (208), Expect = 8e-16
Identities = 182/851 (21%), Positives = 255/851 (29%), Gaps = 192/851 (22%)
Query: 170 DACRGMLCGFGAVCEPNAEGPGRASCVCKKSPCPSVVAPVCGSDASTYSNECELQRAQCS 229
D C C G VC +G +C C P C D +EC LQ C
Sbjct: 262 DDCPNHRCQNGGVC---VDGVNTYNCRCP----PQWTGQFCTEDV----DECLLQPNACQ 310
Query: 230 QQRRIRLLSRGPCGSR---------------------DPCSNVTCSFGSTCARSADGLTA 268
+ G C +R D C+ +C+ GSTC +
Sbjct: 311 --------NGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRV--ASF 360
Query: 269 SCLCPA-----------TCRGAP--EGTVCGSD--GADYPGECQLLRRACARQENVFKKF 313
SC+CP C P +G +C ++ Y C + E+V +
Sbjct: 361 SCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECA 420
Query: 314 DGPCDPCQGA----LPDPSRSCRVNPRTRRPEMLLRPESC---PARQAPVCGDDGVTYEN 366
+PC+ A D + C P + C P + C D +
Sbjct: 421 MANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTC 480
Query: 367 DCVMGRSGAARGLLLQKVRSGQCQGRDQCPEPC-RFNAVCLSRRGRPRCSCDRVTCDGAY 425
C+ G G L + + +S C QC + RF +C P C D C
Sbjct: 481 LCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSST- 539
Query: 426 RPVCAQDGRTYD-SDCWRQQAECRQQRAIPSKHQGPCDQAPSPCLGVQCAFGA---TCAV 481
C + D + + Q + ++ CD P PC QC G TC
Sbjct: 540 --PCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCD--PDPCHHGQCQDGIDSYTCIC 595
Query: 482 KNGQAACECLQACSSLYDPVCGSDGVTYGSACELEATACTLGREIQVARKGPCDRCGQCR 541
G C Y C +D GR I + C+ C
Sbjct: 596 NPGYMGAICSDQIDECYSSPCLND-----------------GRCIDLVNGYQCN-CQPGT 637
Query: 542 FGALCEAETGRCVCPSECVALAQPVCGSDGHTYPSECMLHVHACTHQISLHVASAGPCE- 600
G CE C + C+ +C + Y C I + ++ PC
Sbjct: 638 SGVNCEINFDDC-ASNPCI---HGICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRK 693
Query: 601 --TCGDAVCAFGAVCSAGQCVCPRCEHPPPGPVCGSDGVTYGSACELREAACLQQTQIEE 658
TC + V F +C+CP H P +C +Q+ E
Sbjct: 694 GATCINGVNGF-------RCICPEGPHHP--------------SC---------YSQVNE 723
Query: 659 ARAGPCEQAECGSGGSG--------------SGEDGDCEQELCRQRGGIWDEDSEDGPCV 704
+ PC C G SG + +C C Q GG D C
Sbjct: 724 CLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPC-QNGGTCDNLVNGYRCT 782
Query: 705 C-----DFSCQ-------SVP--GSPVCGSDGVTYSTECELKKARCESQRGLYVAAQGAC 750
C ++CQ S P C D Y+ C L Q L + C
Sbjct: 783 CKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPC 842
Query: 751 RGPTFAPLPPVAPLHCAQTP----YGC-CQDNITAAR-GVGLAGCPSACQCNPHGSYGGT 804
C ++P Y C C R + + C S C HG T
Sbjct: 843 ENAAV----------CKESPNFESYTCLCAPGWQGQRCTIDIDECISK-PCMNHGLCHNT 891
Query: 805 CDPATGQCSCRPGVGGLRC----DRCEPGFWNFRGIVTDGRSGCTPCSCDPQGAVRDDCE 860
+ C C PG G+ C D C G DG + + C C P G D C+
Sbjct: 892 --QGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFS-CLCLP-GFTGDKCQ 947
Query: 861 QMTGLCSCKPGVAGPKCGQ------CPDGRALGPAGCEADASAPATCAEMRCEFGARCVE 914
C +P G C C CE + + C E C G CV+
Sbjct: 948 TDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNIN---ECTESSCFNGGTCVD 1004
Query: 915 ESGSAHCVCPM 925
S C+CP+
Sbjct: 1005 GINSFSCLCPV 1015
Score = 69.7 bits (169), Expect = 3e-11
Identities = 137/610 (22%), Positives = 185/610 (30%), Gaps = 140/610 (22%)
Query: 365 ENDCVMGRSGAARGLLLQKVRSGQCQGRDQCPEP-CRFNAVCLSRR--GRPRC------- 414
E CV +G + CQ RD C + C+ C+++ G+ C
Sbjct: 38 EGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFT 97
Query: 415 --SCDRVTCDGAY--RPVCAQDGRTYDSDCWRQQAECRQQRAIPSKHQGPCDQAPSPCLG 470
C T + RP C G + R EC Q K C Q CL
Sbjct: 98 GEDCQYSTSHPCFVSRP-CLNGGTCHMLS--RDTYECTCQVGFTGKE---C-QWTDACLS 150
Query: 471 VQCAFGATCAVKNGQAACECLQACSSLYDPVCGSDGVTYGSACELEATACTLGREIQVAR 530
CA G+TC Q +C+CL + G CE + C + Q
Sbjct: 151 HPCANGSTCTTVANQFSCKCLTGFT--------------GQKCETDVNECDIPGHCQ--H 194
Query: 531 KGPC--------DRCGQCRFGALCEAETGRCVCPSECVALAQPVCGSDGH-TYPSECMLH 581
G C +C Q G C++ C PS CV C G T+ C+
Sbjct: 195 GGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCA-PSPCVNGG--TCRQTGDFTFECNCLPG 251
Query: 582 VHACTHQISLHVASAGPCETCGDAVCAFGAVCSAGQCVCPRCEHPPP--GPVCGSDGVTY 639
T + ++ + C + C G VC G C PP G C D
Sbjct: 252 FEGSTCERNI--------DDCPNHRCQNGGVCVDGVNTY-NCRCPPQWTGQFCTEDV--- 299
Query: 640 GSACELREAACLQQTQIEEARAG-PCEQAECGSGGSGSGEDGDCEQELCRQRGGIWDEDS 698
C L+ AC G C SG S DC C D
Sbjct: 300 -DECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDR-- 356
Query: 699 EDGPCVCDFSCQSVPGSP--VCGSDGVTYSTECELKKARCESQ--RGLYVAAQGACRGPT 754
V FSC G +C D S C K A C++ G Y+
Sbjct: 357 -----VASFSCMCPEGKAGLLCHLDDACISNPCH-KGALCDTNPLNGQYICT-------- 402
Query: 755 FAPLPPVAPLHCAQTPYGC-CQDNITAARGVGLAGCPSACQC-NPHGSYGGTC------- 805
C Q G C +++ C A +C N G++ C
Sbjct: 403 -----------CPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGP 451
Query: 806 -----------DPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGR-SGCTPCSCDPQG 853
DP +C +GG C C PGF +G+ + + C C G
Sbjct: 452 RCEMDINECHSDPCQNDATCLDKIGGFTC-LCMPGF---KGVHCELEINECQSNPCVNNG 507
Query: 854 AVRDDCEQMTGLCSCKPGVAGPKCGQCPDGRALGPAGCEADASAPATCAEMRCEFGARCV 913
D + C C PG GP C D C+ C GA+C+
Sbjct: 508 QCVDKVNRFQ--CLCPPGFTGPVCQIDIDD-----------------CSSTPCLNGAKCI 548
Query: 914 EESGSAHCVC 923
+ C C
Sbjct: 549 DHPNGYECQC 558
Score = 68.2 bits (165), Expect = 8e-11
Identities = 165/710 (23%), Positives = 218/710 (30%), Gaps = 181/710 (25%)
Query: 152 CVEDKPGTHFTPVPPTPPDACRGMLCGFGAVCEPNAEGPGRASCVCKKSP---------C 202
C +D G V P C+ +L A C PN P + VCK+SP
Sbjct: 810 CFDDISGYTCHCVLPYTGKNCQTVL----APCSPN---PCENAAVCKESPNFESYTCLCA 862
Query: 203 PSVVAPVCGSDASTYSNECELQRAQCSQQRRIRLLSRGPCGSR-------DPCSNVTCSF 255
P C D ++ + C + + P S D C C
Sbjct: 863 PGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQN 922
Query: 256 GSTCARSADGL-TASCLCPA------------TCRGAP--EGTVCGSDGADYPGECQLLR 300
G +C DG+ T SCLC C P G C Y +CQ
Sbjct: 923 GGSCM---DGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGF 979
Query: 301 RACARQENVFKKFDGPC---DPCQGALPDPSRSCRVN-PRTRRPEMLLRPESCPARQAPV 356
+ N+ + + C C + S C V + + S P
Sbjct: 980 DGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGT 1039
Query: 357 CGDDGVTYENDCVMGRSGAARGLLLQKVRSGQCQGRDQCPEPCRFNAVCLSRRGRPRCSC 416
C D TY C +G +G L+ C+ + C + + + CL G C
Sbjct: 1040 CVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQK-KAESQCLCPSGWAGAYC 1098
Query: 417 D--RVTCDGA-------------YRPVCAQDGRTYDSDCWRQQAECRQQRAIPSKHQGP- 460
D V+CD A + VC G T+ C P + G
Sbjct: 1099 DVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQC-------------PLGYTGSY 1145
Query: 461 CDQAPSPCLGVQCAFGATCAVKNGQAACECL-----------------QACSS---LYDP 500
C++ C C GATC+ G CEC+ Q C + D
Sbjct: 1146 CEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDL 1205
Query: 501 V----CGSDGVTYGSACELEATACTLGREIQVARKGPC-DRCG--QCRF-----GALCEA 548
V C T G CE C G G C DR G CR G CE
Sbjct: 1206 VNHFKCSCPPGTRGLLCEENIDDCARGPHC--LNGGQCMDRIGGYSCRCLPGFAGERCEG 1263
Query: 549 ETGRCV---CPSE----CVALAQP-VCGSDGHTYPSECMLHVHACTHQISLH-----VAS 595
+ C+ C SE C+ L +C C V C L+ VAS
Sbjct: 1264 DINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVAS 1323
Query: 596 AGP---------------CET-CGDAVCAFGAVC----SAGQCVCPR------------C 623
P C++ CG C G C S +C CP C
Sbjct: 1324 NMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCASSPC 1383
Query: 624 EH--------PPPGPVCGSDGVTYGSACELREA-------ACLQQTQIEEARAGPCEQAE 668
+H PP C GS CEL A CL Q ++AR G C++A
Sbjct: 1384 QHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCDEA- 1442
Query: 669 CGSGGSGSGEDGDCEQELCRQRGGIWDEDSEDGPC------VCDFSCQSV 712
C S + GDC + W S PC CD C +V
Sbjct: 1443 CNSHAC-QWDGGDCSLTM----ENPWANCSSPLPCWDYINNQCDELCNTV 1487
Score = 60.8 bits (146), Expect = 1e-08
Identities = 33/90 (36%), Positives = 41/90 (45%), Gaps = 5/90 (5%)
Query: 1550 DHPCLPNPCHGGAPCQ-NLEAGRFHCQCPPGRVGPTCADEKSPC---QPNPCHGAAPCRV 1605
D C+ NPCH GA C N G++ C CP G G C ++ C NPC A C V
Sbjct: 376 DDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKC-V 434
Query: 1606 LPEGGAQCECPLGREGTFCQTASGQDGSGP 1635
+G CEC G G C+ + S P
Sbjct: 435 NTDGAFHCECLKGYAGPRCEMDINECHSDP 464
Score = 60.5 bits (145), Expect = 2e-08
Identities = 30/81 (37%), Positives = 37/81 (45%), Gaps = 5/81 (6%)
Query: 1545 VGECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCR 1604
V EC +P C G C NL G + CQCP G G C PC P+PC CR
Sbjct: 183 VNECD----IPGHCQHGGTCLNLP-GSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCR 237
Query: 1605 VLPEGGAQCECPLGREGTFCQ 1625
+ +C C G EG+ C+
Sbjct: 238 QTGDFTFECNCLPGFEGSTCE 258
Score = 59.7 bits (143), Expect = 3e-08
Identities = 27/73 (36%), Positives = 33/73 (45%), Gaps = 2/73 (2%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQ 1612
C NPC C + + RF C CPPG GP C + C PC A C P G +
Sbjct: 498 CQSNPCVNNGQCVD-KVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHP-NGYE 555
Query: 1613 CECPLGREGTFCQ 1625
C+C G G C+
Sbjct: 556 CQCATGFTGVLCE 568
Score = 59.7 bits (143), Expect = 3e-08
Identities = 42/153 (27%), Positives = 60/153 (39%), Gaps = 8/153 (5%)
Query: 1485 DGLNLDTDLFVGGVPEDQAAVALERTFVGAGLRGCIRLLDVNNQRLELGIGPGAATRGSG 1544
DG+N + + G + + ++ +G + VN R GP + S
Sbjct: 661 DGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQ 720
Query: 1545 VGECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCR 1604
V EC +PC+ C GG + C C G VG C +K+ C NPC C
Sbjct: 721 VNECLSNPCIHGNCTGGL-------SGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCD 773
Query: 1605 VLPEGGAQCECPLGREGTFCQTASGQDGSGPFL 1637
L G +C C G +G CQ + S P L
Sbjct: 774 NL-VNGYRCTCKKGFKGYNCQVNIDECASNPCL 805
Score = 59.3 bits (142), Expect = 4e-08
Identities = 74/323 (22%), Positives = 107/323 (33%), Gaps = 48/323 (14%)
Query: 1320 GRRPPAPQQPPKPCDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEKVLGAPVPAFEG 1379
G P + C S PC + TC D GGFTC C G G CE E
Sbjct: 447 GYAGPRCEMDINECHSDPCQNDATCLDKI--GGFTCLCMPGFKGVHCE---------LEI 495
Query: 1380 RSFLAFPTLRAYHTLRLALEFRALEPQGLLLYNGNARGKDFLALALLDGRVQLRFDTGSG 1439
+ P + + F+ L P G + G Q+ D S
Sbjct: 496 NECQSNPCVNNGQCVDKVNRFQCLCPPG---FTGPV--------------CQIDIDDCSS 538
Query: 1440 PAVLTSAVPVEPGQWHRLELSRHWRRGTL---SVDGETPVLGESPSGTDGLNLDTDL--- 1493
L A ++ + + + + G L ++D P DG++ T +
Sbjct: 539 TPCLNGAKCIDHPNGYECQCATGFT-GVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNP 597
Query: 1494 -FVGGVPEDQAAVALERTFVGAGLRGCIRLLDVNNQRLELGIGPGAATRGSGVGECGDHP 1552
++G + DQ + G CI L VN + G +C +P
Sbjct: 598 GYMGAICSDQIDECYSSPCLNDGR--CIDL--VNGYQCNCQPGTSGVNCEINFDDCASNP 653
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQ 1612
C+ C G R+ C C PG G C + C NPC A C + G +
Sbjct: 654 CIHGICMDGI-------NRYSCVCSPGFTGQRCNIDIDECASNPCRKGATC-INGVNGFR 705
Query: 1613 CECPLGREGTFCQTASGQDGSGP 1635
C CP G C + + S P
Sbjct: 706 CICPEGPHHPSCYSQVNECLSNP 728
Score = 58.9 bits (141), Expect = 5e-08
Identities = 29/83 (34%), Positives = 34/83 (40%), Gaps = 2/83 (2%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQ 1612
C NPC GA C + G + C+C PG G C E CQ PC C L +
Sbjct: 1153 CASNPCQHGATCSDFIGG-YRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDL-VNHFK 1210
Query: 1613 CECPLGREGTFCQTASGQDGSGP 1635
C CP G G C+ GP
Sbjct: 1211 CSCPPGTRGLLCEENIDDCARGP 1233
Score = 56.6 bits (135), Expect = 2e-07
Identities = 28/80 (35%), Positives = 37/80 (46%), Gaps = 2/80 (2%)
Query: 1556 NPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQCEC 1615
NPC C N + G FHC+C G GP C + + C +PC A C + GG C C
Sbjct: 425 NPCEHAGKCVNTD-GAFHCECLKGYAGPRCEMDINECHSDPCQNDATC-LDKIGGFTCLC 482
Query: 1616 PLGREGTFCQTASGQDGSGP 1635
G +G C+ + S P
Sbjct: 483 MPGFKGVHCELEINECQSNP 502
Score = 56.2 bits (134), Expect = 3e-07
Identities = 27/75 (36%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQ-PNPCHGAAPCRVLPEGGA 1611
CL +PC G+ C + A +F C+C G G C + + C P C C LP G
Sbjct: 148 CLSHPCANGSTCTTV-ANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLP-GSY 205
Query: 1612 QCECPLGREGTFCQT 1626
QC+CP G G +C +
Sbjct: 206 QCQCPQGFTGQYCDS 220
Score = 54.7 bits (130), Expect = 9e-07
Identities = 118/507 (23%), Positives = 158/507 (31%), Gaps = 126/507 (24%)
Query: 457 HQGPCDQAPSPCLGVQCAFGATCAVKNGQAACECLQACSSLY----DPVCGSDGVTYGSA 512
H C PC+ G NG C+C + Y DP C + G
Sbjct: 24 HALQCRDGYEPCVNE----GMCVTYHNGTGYCKCPEGFLGEYCQHRDP-CEKNRCQNGGT 78
Query: 513 CELEATACTLGREIQVARKGPCDRCGQCRFGALCEAETGR-CVCPSECVALAQPVCGSDG 571
C +A LG K C RC G C+ T C C+ G
Sbjct: 79 CVAQAM---LG-------KATC-RCASGFTGEDCQYSTSHPCFVSRPCLN------GGTC 121
Query: 572 HTYPSECMLHVHACTHQISLHVASAGPCETCGDAVCAFGAVCS--AGQCVCPRCEHPPPG 629
H + + CT Q+ + C CA G+ C+ A Q C +C G
Sbjct: 122 HMLSRD----TYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSC-KCLTGFTG 176
Query: 630 PVCGSDGVTYGSACEL-----REAACLQ-----QTQIEEARAG--------PCEQAECGS 671
C +D + C++ CL Q Q + G PC + C +
Sbjct: 177 QKCETDV----NECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVN 232
Query: 672 GGSGSGEDGDCEQELCRQRGGIWDEDSEDGPCVCDFSCQSVPGSPVCGSDGVTYSTECEL 731
GG+ CRQ G F C +PG +G T CE
Sbjct: 233 GGT------------CRQTGDF------------TFECNCLPGF-----EGST----CER 259
Query: 732 KKARCESQR----GLYVAAQGA--CRGPTFAPLPPVAPLHCAQTPYGC------CQDNIT 779
C + R G+ V CR P P C + C CQ+ T
Sbjct: 260 NIDDCPNHRCQNGGVCVDGVNTYNCRCP-----PQWTGQFCTEDVDECLLQPNACQNGGT 314
Query: 780 AARGVGLAGCPSACQCNPHGSYGGTCDPATGQC---SCRPGVGGLRCDRCEPGFWNFRGI 836
A G GC +G G C C SC PG C +F +
Sbjct: 315 CANRNGGYGCVCV-----NGWSGDDCSENIDDCAFASCTPG------STCIDRVASFSCM 363
Query: 837 VTDGRSGCTPCSCDPQGAVRDDCEQMTGLCSCKPGVAGPKCGQCPDGRALGPAGCEADAS 896
+G++G C D + + C + LC P + G CP G A C D
Sbjct: 364 CPEGKAGLL-CHLD-DACISNPCHK-GALCDTNP-LNGQYICTCPQGYK--GADCTEDVD 417
Query: 897 APATCAEMRCEFGARCVEESGSAHCVC 923
A CE +CV G+ HC C
Sbjct: 418 ECAMANSNPCEHAGKCVNTDGAFHCEC 444
Score = 54.7 bits (130), Expect = 9e-07
Identities = 36/108 (33%), Positives = 44/108 (40%), Gaps = 12/108 (11%)
Query: 1552 PCLPNPCHGGAPCQ---NLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPE 1608
PC PNPC A C+ N E+ + C C PG G C + C PC C +
Sbjct: 836 PCSPNPCENAAVCKESPNFES--YTCLCAPGWQGQRCTIDIDECISKPCMNHGLCH-NTQ 892
Query: 1609 GGAQCECPLGREGTFCQ------TASGQDGSGPFLADFNGFSHLELRG 1650
G CECP G G C+ A+ G + N FS L L G
Sbjct: 893 GSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPG 940
Score = 54.3 bits (129), Expect = 1e-06
Identities = 85/366 (23%), Positives = 124/366 (33%), Gaps = 63/366 (17%)
Query: 616 GQCVCPR------CEHPPP--------GPVCGSDGVTYGSACELREAACLQQTQIEEARA 661
G C CP C+H P G C + + + C R A+ + + +
Sbjct: 49 GYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATC--RCASGFTGEDCQYSTS 106
Query: 662 GPCEQAE-CGSGGSGSGEDGDCEQELCRQ----RGGIWDEDSEDGPCVCDFSCQSVPGSP 716
PC + C +GG+ D + C+ + W + PC +C +V
Sbjct: 107 HPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQF 166
Query: 717 VCGSDGVTYSTECELKKARCESQRGLYVAAQGACR-GPTFAPLPPVAPLHCAQTPYGCCQ 775
C +CE C+ G C+ G T LP C Q G
Sbjct: 167 SCKCLTGFTGQKCETDVNECD--------IPGHCQHGGTCLNLPGSYQCQCPQGFTGQYC 218
Query: 776 DNITAARGVGLAGCPSACQCNPHGSYGGTCDPA---TGQCSCRPGVGGLRCDRCEPGFWN 832
D++ + PS C GGTC T +C+C PG G C+R N
Sbjct: 219 DSLY------VPCAPSPCV------NGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPN 266
Query: 833 FR----GIVTDGRSGCTPCSCDPQGAVRDDCEQMTGLCSCKPGVA--GPKCGQCPDGRAL 886
R G+ DG + C C PQ + C + C +P G C G
Sbjct: 267 HRCQNGGVCVDGVNTYN-CRCPPQWTGQF-CTEDVDECLLQPNACQNGGTCANRNGGYGC 324
Query: 887 ----GPAGCEADASAPATCAEMRCEFGARCVEESGSAHCVCPMLTCPEANATKVCGSDGV 942
G +G + + CA C G+ C++ S C+ CPE A +C D
Sbjct: 325 VCVNGWSGDDCSENID-DCAFASCTPGSTCIDRVASFSCM-----CPEGKAGLLCHLDDA 378
Query: 943 TYGNEC 948
N C
Sbjct: 379 CISNPC 384
Score = 53.1 bits (126), Expect = 3e-06
Identities = 27/81 (33%), Positives = 34/81 (41%), Gaps = 9/81 (11%)
Query: 1545 VGECGDHPCL-PNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPC 1603
+ EC HPCL C G G + C CP G G C + C +PC C
Sbjct: 1026 INECSSHPCLNEGTCVDGL-------GTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTC 1078
Query: 1604 RVLPEGGAQCECPLGREGTFC 1624
V + +QC CP G G +C
Sbjct: 1079 -VQKKAESQCLCPSGWAGAYC 1098
Score = 52.4 bits (124), Expect = 5e-06
Identities = 29/80 (36%), Positives = 31/80 (38%), Gaps = 2/80 (2%)
Query: 1547 ECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVL 1606
E + CL NPC G C NL G + C C G G C C NPC C
Sbjct: 755 EVDKNECLSNPCQNGGTCDNLVNG-YRCTCKKGFKGYNCQVNIDECASNPCLNQGTC-FD 812
Query: 1607 PEGGAQCECPLGREGTFCQT 1626
G C C L G CQT
Sbjct: 813 DISGYTCHCVLPYTGKNCQT 832
Score = 52.0 bits (123), Expect = 6e-06
Identities = 32/85 (37%), Positives = 36/85 (42%), Gaps = 2/85 (2%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQ 1612
C +PC A C + + G F C C PG G C E + CQ NPC C V Q
Sbjct: 460 CHSDPCQNDATCLD-KIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQC-VDKVNRFQ 517
Query: 1613 CECPLGREGTFCQTASGQDGSGPFL 1637
C CP G G CQ S P L
Sbjct: 518 CLCPPGFTGPVCQIDIDDCSSTPCL 542
Score = 51.6 bits (122), Expect = 8e-06
Identities = 30/100 (30%), Positives = 37/100 (37%), Gaps = 8/100 (8%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQ 1612
CL NPC G C + F C C PG G C + + C PC C
Sbjct: 915 CLANPCQNGGSCMD-GVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDY-VNSYT 972
Query: 1613 CECPLGREGTFCQ------TASGQDGSGPFLADFNGFSHL 1646
C+C G +G C+ T S G + N FS L
Sbjct: 973 CKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCL 1012
Score = 51.2 bits (121), Expect = 1e-05
Identities = 27/83 (32%), Positives = 35/83 (42%), Gaps = 2/83 (2%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQ 1612
C+ PC C N + G + C+CPPG G C ++ C NPC C +
Sbjct: 877 CISKPCMNHGLCHNTQ-GSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSC-MDGVNTFS 934
Query: 1613 CECPLGREGTFCQTASGQDGSGP 1635
C C G G CQT + S P
Sbjct: 935 CLCLPGFTGDKCQTDMNECLSEP 957
Score = 51.2 bits (121), Expect = 1e-05
Identities = 27/74 (36%), Positives = 32/74 (43%), Gaps = 2/74 (2%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQ 1612
C + C G C + F C CP G G C E + C +PC C V G +
Sbjct: 991 CTESSCFNGGTCVD-GINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTC-VDGLGTYR 1048
Query: 1613 CECPLGREGTFCQT 1626
C CPLG G CQT
Sbjct: 1049 CSCPLGYTGKNCQT 1062
Score = 50.8 bits (120), Expect = 1e-05
Identities = 25/73 (34%), Positives = 28/73 (38%), Gaps = 1/73 (1%)
Query: 1552 PCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGA 1611
PC P+PC G C+ F C C PG G TC C + C C V
Sbjct: 224 PCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVC-VDGVNTY 282
Query: 1612 QCECPLGREGTFC 1624
C CP G FC
Sbjct: 283 NCRCPPQWTGQFC 295
Score = 50.8 bits (120), Expect = 1e-05
Identities = 27/69 (39%), Positives = 32/69 (46%), Gaps = 4/69 (5%)
Query: 1558 CHGGAPCQNLEAGRFH-CQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQCECP 1616
C C N AG H CQCP G G C ++ C NPC A C GG +CEC
Sbjct: 1120 CQHSGVCIN--AGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDF-IGGYRCECV 1176
Query: 1617 LGREGTFCQ 1625
G +G C+
Sbjct: 1177 PGYQGVNCE 1185
Score = 48.1 bits (113), Expect = 9e-05
Identities = 33/103 (32%), Positives = 42/103 (40%), Gaps = 15/103 (14%)
Query: 1535 GPGAATRGSGVG----------ECGDH--PCLPNPCHGGAPCQNLEAGRFHCQCPPGRVG 1582
G A R G G +C ++ C C G+ C + A F C CP G+ G
Sbjct: 312 GGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVAS-FSCMCPEGKAG 370
Query: 1583 PTCADEKSPCQPNPCHGAAPCRVLPEGGAQ-CECPLGREGTFC 1624
C + + C NPCH A C P G C CP G +G C
Sbjct: 371 LLCHLDDA-CISNPCHKGALCDTNPLNGQYICTCPQGYKGADC 412
Score = 47.8 bits (112), Expect = 1e-04
Identities = 25/73 (34%), Positives = 31/73 (42%), Gaps = 2/73 (2%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPE-GGA 1611
C NPC C + +G + C C G C +PC PNPC AA C+ P
Sbjct: 799 CASNPCLNQGTCFDDISG-YTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESY 857
Query: 1612 QCECPLGREGTFC 1624
C C G +G C
Sbjct: 858 TCLCAPGWQGQRC 870
Score = 46.2 bits (108), Expect = 3e-04
Identities = 25/85 (29%), Positives = 34/85 (40%), Gaps = 2/85 (2%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQ 1612
CL PC G C + + C+C G G C + + C + C C V
Sbjct: 953 CLSEPCKNGGTCSDY-VNSYTCKCQAGFDGVHCENNINECTESSCFNGGTC-VDGINSFS 1010
Query: 1613 CECPLGREGTFCQTASGQDGSGPFL 1637
C CP+G G+FC + S P L
Sbjct: 1011 CLCPVGFTGSFCLHEINECSSHPCL 1035
Score = 45.8 bits (107), Expect = 4e-04
Identities = 29/89 (32%), Positives = 36/89 (40%), Gaps = 7/89 (7%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEG--G 1610
C PC GA C + G + CQC G G C + C P+PCH C+ +G
Sbjct: 536 CSSTPCLNGAKCIDHPNG-YECQCATGFTGVLCEENIDNCDPDPCH-HGQCQ---DGIDS 590
Query: 1611 AQCECPLGREGTFCQTASGQDGSGPFLAD 1639
C C G G C + S P L D
Sbjct: 591 YTCICNPGYMGAICSDQIDECYSSPCLND 619
Score = 45.4 bits (106), Expect = 6e-04
Identities = 23/70 (32%), Positives = 28/70 (40%), Gaps = 2/70 (2%)
Query: 1557 PCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPE-GGAQCEC 1615
PC C G +C+CP G +G C + PC+ N C C G A C C
Sbjct: 34 PCVNEGMCVTYHNGTGYCKCPEGFLGEYC-QHRDPCEKNRCQNGGTCVAQAMLGKATCRC 92
Query: 1616 PLGREGTFCQ 1625
G G CQ
Sbjct: 93 ASGFTGEDCQ 102
Score = 45.4 bits (106), Expect = 6e-04
Identities = 18/42 (42%), Positives = 23/42 (54%)
Query: 1812 SFAGHPCTRASGHPCLNGASCVPREAAYVCLCPGGFSGPHCE 1853
SF H S HPCLN +CV Y C CP G++G +C+
Sbjct: 1020 SFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQ 1061
Score = 44.7 bits (104), Expect = 0.001
Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 8/72 (11%)
Query: 1813 FAGHPC----TRASGHPCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVEKSAGDVDTLA 1868
F G C PC NG +C +Y C C GF G HCE + E + ++
Sbjct: 941 FTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECT----ESSC 996
Query: 1869 FDGRTFVEYLNA 1880
F+G T V+ +N+
Sbjct: 997 FNGGTCVDGINS 1008
Score = 44.7 bits (104), Expect = 0.001
Identities = 22/51 (43%), Positives = 28/51 (54%), Gaps = 2/51 (3%)
Query: 1318 VPGRRPPAPQQPPKPCDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEK 1368
VPG + + C +QPC +GGTC D L F CSCP G G +CE+
Sbjct: 1176 VPGYQGVNCEYEVDECQNQPCQNGGTCID--LVNHFKCSCPPGTRGLLCEE 1224
Score = 44.3 bits (103), Expect = 0.001
Identities = 28/83 (33%), Positives = 33/83 (39%), Gaps = 7/83 (8%)
Query: 1553 CLPNPC--HGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRV---LP 1607
CL NPC G C L + C C G C C PC C V +P
Sbjct: 1268 CLSNPCSSEGSLDCIQL-TNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMP 1326
Query: 1608 EGGAQCECPLGREGTFCQTASGQ 1630
+G C CP G G CQ++ GQ
Sbjct: 1327 DGFI-CRCPPGFSGARCQSSCGQ 1348
Score = 43.9 bits (102), Expect = 0.002
Identities = 23/77 (29%), Positives = 30/77 (38%), Gaps = 3/77 (3%)
Query: 1551 HPC-LPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEG 1609
HPC + PC G C L + C C G G C C +PC + C +
Sbjct: 107 HPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKEC-QWTDACLSHPCANGSTCTTV-AN 164
Query: 1610 GAQCECPLGREGTFCQT 1626
C+C G G C+T
Sbjct: 165 QFSCKCLTGFTGQKCET 181
Score = 43.1 bits (100), Expect = 0.003
Identities = 23/74 (31%), Positives = 30/74 (40%), Gaps = 4/74 (5%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPC--QPNPCHGAAPCRVLPEGG 1610
C + C G C + ++C+CPP G C ++ C QPN C C GG
Sbjct: 264 CPNHRCQNGGVCVD-GVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTC-ANRNGG 321
Query: 1611 AQCECPLGREGTFC 1624
C C G G C
Sbjct: 322 YGCVCVNGWSGDDC 335
Score = 42.0 bits (97), Expect = 0.006
Identities = 20/50 (40%), Positives = 25/50 (50%), Gaps = 2/50 (4%)
Query: 1318 VPGRRPPAPQQPPKPCDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCE 1367
+PG Q C S+PC +GGTC D+ +TC C AG G CE
Sbjct: 938 LPGFTGDKCQTDMNECLSEPCKNGGTCSDYV--NSYTCKCQAGFDGVHCE 985
Score = 41.2 bits (95), Expect = 0.010
Identities = 20/66 (30%), Positives = 31/66 (46%), Gaps = 1/66 (1%)
Query: 1793 LGGRQLLTPEHVLRQVDVTSFAGHPCTRASGHPCLNGASCVPREAAYVCLCPGGFSGPHC 1852
L G+ + T + D T C A+ +PC + CV + A+ C C G++GP C
Sbjct: 395 LNGQYICTCPQGYKGADCTEDVDE-CAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRC 453
Query: 1853 EKGLVE 1858
E + E
Sbjct: 454 EMDINE 459
Score = 41.2 bits (95), Expect = 0.010
Identities = 14/30 (46%), Positives = 20/30 (66%)
Query: 1824 HPCLNGASCVPREAAYVCLCPGGFSGPHCE 1853
+PC+N CV + + CLCP GF+GP C+
Sbjct: 501 NPCVNNGQCVDKVNRFQCLCPPGFTGPVCQ 530
Score = 41.2 bits (95), Expect = 0.010
Identities = 16/35 (45%), Positives = 20/35 (57%)
Query: 1822 SGHPCLNGASCVPREAAYVCLCPGGFSGPHCEKGL 1856
S PCLNGA C+ Y C C GF+G CE+ +
Sbjct: 537 SSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENI 571
Score = 40.4 bits (93), Expect = 0.018
Identities = 17/35 (48%), Positives = 19/35 (54%), Gaps = 2/35 (5%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCE 1367
C S PC HG TC D+ GG+ C C G G CE
Sbjct: 1153 CASNPCQHGATCSDFI--GGYRCECVPGYQGVNCE 1185
Score = 40.0 bits (92), Expect = 0.023
Identities = 17/45 (37%), Positives = 22/45 (48%), Gaps = 4/45 (8%)
Query: 1813 FAGHPC----TRASGHPCLNGASCVPREAAYVCLCPGGFSGPHCE 1853
+AG C PC N A+C+ + + CLC GF G HCE
Sbjct: 448 YAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCE 492
Score = 39.3 bits (90), Expect = 0.040
Identities = 15/36 (41%), Positives = 24/36 (66%), Gaps = 3/36 (8%)
Query: 1818 CTRASGHPCLNGASCVPREAAYVCLCPGGFSGPHCE 1853
C+R+ PC N +CV ++A CLCP G++G +C+
Sbjct: 1067 CSRS---PCKNKGTCVQKKAESQCLCPSGWAGAYCD 1099
Score = 39.3 bits (90), Expect = 0.040
Identities = 17/38 (44%), Positives = 20/38 (52%)
Query: 1821 ASGHPCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVE 1858
A G CLNG C+ R Y C C GF+G CE + E
Sbjct: 1230 ARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINE 1267
Score = 39.3 bits (90), Expect = 0.040
Identities = 17/40 (42%), Positives = 21/40 (52%), Gaps = 1/40 (2%)
Query: 1333 CDSQPCFHGGTCQDWA-LGGGFTCSCPAGRGGAVCEKVLG 1371
C PC +GGTC + + GF C CP G GA C+ G
Sbjct: 1308 CPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCG 1347
Score = 38.9 bits (89), Expect = 0.052
Identities = 14/32 (43%), Positives = 20/32 (62%)
Query: 1825 PCLNGASCVPREAAYVCLCPGGFSGPHCEKGL 1856
PC+N C + +Y+C CP GFSG CE+ +
Sbjct: 881 PCMNHGLCHNTQGSYMCECPPGFSGMDCEEDI 912
Score = 38.9 bits (89), Expect = 0.052
Identities = 24/77 (31%), Positives = 31/77 (40%), Gaps = 5/77 (6%)
Query: 1553 CLPNP-CHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPC--HGAAPCRVLPEG 1609
C P C G C + G + C+C PG G C + + C NPC G+ C L
Sbjct: 1229 CARGPHCLNGGQCMD-RIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQL-TN 1286
Query: 1610 GAQCECPLGREGTFCQT 1626
C C G C+T
Sbjct: 1287 DYLCVCRSAFTGRHCET 1303
Score = 37.7 bits (86), Expect = 0.12
Identities = 22/74 (29%), Positives = 34/74 (45%), Gaps = 8/74 (10%)
Query: 1813 FAGHPCTR----ASGHPCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVEKSAGDVDTLA 1868
F+G C +PC NG SC+ + CLC GF+G C+ + E +
Sbjct: 903 FSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNE----CLSEPC 958
Query: 1869 FDGRTFVEYLNAVT 1882
+G T +Y+N+ T
Sbjct: 959 KNGGTCSDYVNSYT 972
Score = 37.7 bits (86), Expect = 0.12
Identities = 16/35 (45%), Positives = 21/35 (60%), Gaps = 3/35 (8%)
Query: 1818 CTRASGHPCLNGASCVPREAAYVCLCPGGFSGPHC 1852
CT +S C NG +CV ++ CLCP GF+G C
Sbjct: 991 CTESS---CFNGGTCVDGINSFSCLCPVGFTGSFC 1022
Score = 37.7 bits (86), Expect = 0.12
Identities = 16/38 (42%), Positives = 21/38 (55%), Gaps = 2/38 (5%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEKVL 1370
C S PC + GTC D G + CSCP G G C+ ++
Sbjct: 1029 CSSHPCLNEGTCVDGL--GTYRCSCPLGYTGKNCQTLV 1064
Score = 37.7 bits (86), Expect = 0.12
Identities = 16/50 (32%), Positives = 22/50 (44%)
Query: 1324 PAPQQPPKPCDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEKVLGAP 1373
P+P+ C S PC HGG+C ++C C G+ CE P
Sbjct: 1369 PSPRDCESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPP 1418
Score = 37.4 bits (85), Expect = 0.15
Identities = 17/50 (34%), Positives = 25/50 (50%), Gaps = 7/50 (14%)
Query: 1810 VTSFAGHPCTR------ASGHPCLNGASCVPREAAYVCLCPGGFSGPHCE 1853
+T F G C GH C +G +C+ +Y C CP GF+G +C+
Sbjct: 171 LTGFTGQKCETDVNECDIPGH-CQHGGTCLNLPGSYQCQCPQGFTGQYCD 219
Score = 37.4 bits (85), Expect = 0.15
Identities = 15/34 (44%), Positives = 17/34 (50%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVC 1366
C S PC G C L G + C+CP G GA C
Sbjct: 379 CISNPCHKGALCDTNPLNGQYICTCPQGYKGADC 412
Score = 37.4 bits (85), Expect = 0.15
Identities = 18/50 (36%), Positives = 22/50 (44%), Gaps = 2/50 (4%)
Query: 1319 PGRRPPAPQQPPKPCDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEK 1368
PG P Q C S PC +G C D G+ C C G G +CE+
Sbjct: 522 PGFTGPVCQIDIDDCSSTPCLNGAKCIDHP--NGYECQCATGFTGVLCEE 569
Score = 36.6 bits (83), Expect = 0.26
Identities = 15/36 (41%), Positives = 20/36 (55%)
Query: 1332 PCDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCE 1367
PC+ C +GGTC A+ G TC C +G G C+
Sbjct: 67 PCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQ 102
Score = 36.6 bits (83), Expect = 0.26
Identities = 17/50 (34%), Positives = 24/50 (48%), Gaps = 7/50 (14%)
Query: 1811 TSFAGHPCTRASGH------PCLNGASC-VPREAAYVCLCPGGFSGPHCE 1853
+ F G C ++ H PCLNG +C + Y C C GF+G C+
Sbjct: 94 SGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQ 143
Score = 36.6 bits (83), Expect = 0.26
Identities = 17/49 (34%), Positives = 22/49 (44%), Gaps = 3/49 (6%)
Query: 1813 FAGHPCTRASG---HPCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVE 1858
F G C HPC NG++C + C C GF+G CE + E
Sbjct: 137 FTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNE 185
Score = 36.6 bits (83), Expect = 0.26
Identities = 15/34 (44%), Positives = 18/34 (52%), Gaps = 2/34 (5%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVC 1366
C CF+GGTC D F+C CP G G+ C
Sbjct: 991 CTESSCFNGGTCVDGI--NSFSCLCPVGFTGSFC 1022
Score = 36.2 bits (82), Expect = 0.34
Identities = 19/44 (43%), Positives = 22/44 (50%), Gaps = 4/44 (9%)
Query: 1338 CFHGGTCQDWALGGGFTCSCPAGRGGAVCEK--VLGAPVPAFEG 1379
C HGGTC + L G + C CP G G C+ V AP P G
Sbjct: 192 CQHGGTCLN--LPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNG 233
Score = 36.2 bits (82), Expect = 0.34
Identities = 17/39 (43%), Positives = 22/39 (56%), Gaps = 5/39 (12%)
Query: 1332 PCDSQPCFHGGTCQDWALGGGFT--CSCPAGRGGAVCEK 1368
PC PC +GGTC+ G FT C+C G G+ CE+
Sbjct: 224 PCAPSPCVNGGTCRQ---TGDFTFECNCLPGFEGSTCER 259
Score = 36.2 bits (82), Expect = 0.34
Identities = 14/32 (43%), Positives = 18/32 (56%), Gaps = 3/32 (9%)
Query: 1825 PCLNGASCVPREA---AYVCLCPGGFSGPHCE 1853
PCLNG +C ++C CP GFSG C+
Sbjct: 1312 PCLNGGTCAVASNMPDGFICRCPPGFSGARCQ 1343
Score = 35.4 bits (80), Expect = 0.58
Identities = 12/31 (38%), Positives = 17/31 (54%)
Query: 1826 CLNGASCVPREAAYVCLCPGGFSGPHCEKGL 1856
C NG +C R Y C+C G+SG C + +
Sbjct: 309 CQNGGTCANRNGGYGCVCVNGWSGDDCSENI 339
Score = 34.3 bits (77), Expect = 1.3
Identities = 14/36 (38%), Positives = 19/36 (52%), Gaps = 2/36 (5%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEK 1368
C S+PC + G C + G + C CP G G CE+
Sbjct: 877 CISKPCMNHGLCHNTQ--GSYMCECPPGFSGMDCEE 910
Score = 33.9 bits (76), Expect = 1.7
Identities = 15/35 (42%), Positives = 20/35 (57%), Gaps = 2/35 (5%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCE 1367
C S PC +GGTC + L G+ C+C G G C+
Sbjct: 761 CLSNPCQNGGTCDN--LVNGYRCTCKKGFKGYNCQ 793
Score = 33.5 bits (75), Expect = 2.2
Identities = 17/50 (34%), Positives = 21/50 (42%), Gaps = 4/50 (8%)
Query: 1813 FAGHPCTR----ASGHPCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVE 1858
F G C R H C NG CV Y C CP ++G C + + E
Sbjct: 252 FEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDE 301
Score = 33.5 bits (75), Expect = 2.2
Identities = 14/37 (37%), Positives = 19/37 (51%), Gaps = 2/37 (5%)
Query: 1824 HPCLNGASCV--PREAAYVCLCPGGFSGPHCEKGLVE 1858
+PC GA C P Y+C CP G+ G C + + E
Sbjct: 382 NPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDE 418
Score = 33.5 bits (75), Expect = 2.2
Identities = 21/64 (32%), Positives = 26/64 (40%), Gaps = 4/64 (6%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEKVLG--APVPAFEGRSFLAFPTLRA 1390
C S PC + GTC D G+TC C G C+ VL +P P P +
Sbjct: 799 CASNPCLNQGTCFDDI--SGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFES 856
Query: 1391 YHTL 1394
Y L
Sbjct: 857 YTCL 860
Score = 33.1 bits (74), Expect = 2.9
Identities = 14/44 (31%), Positives = 20/44 (45%), Gaps = 4/44 (9%)
Query: 1813 FAGHPCT----RASGHPCLNGASCVPREAAYVCLCPGGFSGPHC 1852
F G C + +PC GA+C+ + C+CP G P C
Sbjct: 674 FTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSC 717
Score = 33.1 bits (74), Expect = 2.9
Identities = 13/38 (34%), Positives = 20/38 (52%)
Query: 1825 PCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVEKSAG 1862
PC NG +C+ + C CP G G CE+ + + + G
Sbjct: 1195 PCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARG 1232
Score = 32.7 bits (73), Expect = 3.7
Identities = 15/49 (30%), Positives = 26/49 (53%), Gaps = 4/49 (8%)
Query: 1808 VDVTSFAGHPCTR----ASGHPCLNGASCVPREAAYVCLCPGGFSGPHC 1852
V V ++G C+ + C G++C+ R A++ C+CP G +G C
Sbjct: 325 VCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLC 373
Score = 32.7 bits (73), Expect = 3.7
Identities = 13/29 (44%), Positives = 15/29 (51%)
Query: 1825 PCLNGASCVPREAAYVCLCPGGFSGPHCE 1853
PCLN C+ Y C C G SG +CE
Sbjct: 615 PCLNDGRCIDLVNGYQCNCQPGTSGVNCE 643
Score = 32.7 bits (73), Expect = 3.7
Identities = 13/35 (37%), Positives = 18/35 (51%)
Query: 1824 HPCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVE 1858
+PC NG +C Y C C GF G +C+ + E
Sbjct: 764 NPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDE 798
Score = 32.7 bits (73), Expect = 3.7
Identities = 13/42 (30%), Positives = 20/42 (47%)
Query: 1812 SFAGHPCTRASGHPCLNGASCVPREAAYVCLCPGGFSGPHCE 1853
S+ + +PC +GA+C Y C C G+ G +CE
Sbjct: 1144 SYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCE 1185
Score = 32.7 bits (73), Expect = 3.7
Identities = 16/47 (34%), Positives = 22/47 (46%), Gaps = 6/47 (12%)
Query: 1813 FAGHPC----TRASGHPCLNGAS--CVPREAAYVCLCPGGFSGPHCE 1853
FAG C +PC + S C+ Y+C+C F+G HCE
Sbjct: 1256 FAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCE 1302
Score = 32.3 bits (72), Expect = 4.9
Identities = 12/35 (34%), Positives = 19/35 (54%)
Query: 1824 HPCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVE 1858
H C + C+ + C CP G++G +CE+ L E
Sbjct: 1118 HLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDE 1152
Score = 32.0 bits (71), Expect = 6.4
Identities = 16/60 (26%), Positives = 26/60 (43%), Gaps = 4/60 (6%)
Query: 1813 FAGHPCT----RASGHPCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVEKSAGDVDTLA 1868
F G+ C + +PCLN +C + Y C C ++G +C+ L S + A
Sbjct: 787 FKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAA 846
Score = 32.0 bits (71), Expect = 6.4
Identities = 16/38 (42%), Positives = 19/38 (50%), Gaps = 5/38 (13%)
Query: 1817 PCTRASGHPCLNGASCV--PREAAYVCLCPGGFSGPHC 1852
PC S +PC N A C P +Y CLC G+ G C
Sbjct: 836 PC---SPNPCENAAVCKESPNFESYTCLCAPGWQGQRC 870
Score = 32.0 bits (71), Expect = 6.4
Identities = 18/50 (36%), Positives = 23/50 (46%), Gaps = 3/50 (6%)
Query: 1319 PGRRPPAPQQPPKPCDSQP-CFHGGTCQDWALGGGFTCSCPAGRGGAVCE 1367
PG R ++ C P C +GG C D GG++C C G G CE
Sbjct: 1215 PGTRGLLCEENIDDCARGPHCLNGGQCMDRI--GGYSCRCLPGFAGERCE 1262
Score = 31.6 bits (70), Expect = 8.3
Identities = 24/69 (34%), Positives = 27/69 (39%), Gaps = 15/69 (21%)
Query: 1309 RPPTTAPSRVPGRRPPAPQQPPKP--------CDSQPCFHGGTCQDWALGG--GFTCSCP 1358
R T + V G R P+ P P C S PC HG GG G+ C C
Sbjct: 692 RKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGN-----CTGGLSGYKCLCD 746
Query: 1359 AGRGGAVCE 1367
AG G CE
Sbjct: 747 AGWVGINCE 755
>gi|41327708 crumbs homolog 1 precursor [Homo sapiens]
Length = 1406
Score = 109 bits (272), Expect = 3e-23
Identities = 135/549 (24%), Positives = 222/549 (40%), Gaps = 67/549 (12%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVC-EKVLGAPVPAFEGRSFLAFPTLRAY 1391
C+SQPC G C + L + C C G C + + + ++ F +Y
Sbjct: 676 CESQPCQSRGRCINLWLS--YQCDCHRPYEGPNCLREYVAGRFGQDDSTGYVIFTLDESY 733
Query: 1392 -HTLRLALEFRALEPQGLLLYNGNARGKDFLALALLDGRVQLRFDTGSGPAVLTSAVPVE 1450
T+ L++ R L+P GLLL N+ + ++ + L GR+ + T + P ++ V +
Sbjct: 734 GDTISLSMFVRTLQPSGLLLALENSTYQ-YIRVWLERGRLAML--TPNSPKLVVKFV-LN 789
Query: 1451 PGQWHRLELSRHWRRGTLSVDGETPVLGESPSGTDGLNLDTDLFVGGVPEDQAAVALERT 1510
G H + L + L + LG + T + +++GG+P+ Q E
Sbjct: 790 DGNVHLISLKIKPYKIELYQSSQN--LGFISASTWKIEKGDVIYIGGLPDKQ-----ETE 842
Query: 1511 FVGAGLRGCIRLLDVNNQRLELGIGPGAATRGSGV------GECGDHPCLPNPCHGGAPC 1564
G +GCI+ + +NNQ LE P + V G GD+ C NPCH G C
Sbjct: 843 LNGGFFKGCIQDVRLNNQNLEFFPNPTNNASLNPVLVNVTQGCAGDNSCKSNPCHNGGVC 902
Query: 1565 QNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQCECPLGREGTFC 1624
+ F C CP G C +E C +PC A C+ + +G EC
Sbjct: 903 HS-RWDDFSCSCPALTSGKAC-EEVQWCGFSPCPHGAQCQPVLQG---FECIANA----- 952
Query: 1625 QTASGQDGSGPFLADFNGFSHLELRGLHTFARDLGEKMALEVVFLARGPSGLLLYNGQKT 1684
+GQ SG L NG EL + TF F R + ++L+
Sbjct: 953 -VFNGQ--SGQILFRSNGNITRELTNI-TFG------------FRTRDANVIILH----A 992
Query: 1685 DGKGDFVSLALRDRRLEFRYDLGKGAAVIR--SREPVTLGAWTRVSLERNGRKGALRVGD 1742
+ + +F++++++D RL F+ G ++ S + V G W V+L
Sbjct: 993 EKEPEFLNISIQDSRLFFQLQSGNSFYMLSLTSLQSVNDGTWHEVTLSMTDPLSQTSRWQ 1052
Query: 1743 GPRVLGESPVPHTVLNLKEPLYVGGAPDFSKLARAAAVSSGFDGAIQLVSLGGRQLLTPE 1802
V E+P + + ++ D RA G G + + +GG L E
Sbjct: 1053 -MEVDNETPFVTSTIATGSLNFLKDNTDIYVGDRAIDNIKGLQGCLSTIEIGGIYLSYFE 1111
Query: 1803 HVLRQVDV----------TSFAGHPCTR---ASGHPCLNGASCVPREAAYVCLCPGGFSG 1849
+V ++ T+ C + + +PCL+G +C ++Y C CP G+SG
Sbjct: 1112 NVHGFINKPQEEQFLKISTNSVVTGCLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSG 1171
Query: 1850 PHCEKGLVE 1858
HCE + E
Sbjct: 1172 KHCELNIDE 1180
Score = 88.2 bits (217), Expect = 7e-17
Identities = 95/350 (27%), Positives = 136/350 (38%), Gaps = 85/350 (24%)
Query: 1333 CDSQPCFHGGTCQD-WALGGGFTCSCPAGRGGAVCEKVLG---APVPAFEGRSFLAFPTL 1388
C S PC +GG C W F+CSCPA G CE+V +P P P L
Sbjct: 891 CKSNPCHNGGVCHSRW---DDFSCSCPALTSGKACEEVQWCGFSPCP----HGAQCQPVL 943
Query: 1389 RAYHTLRLALEFRALEPQGLLLYNGNA------------------------RGKDFLALA 1424
+ + + A+ F Q L NGN + +FL ++
Sbjct: 944 QGFECIANAV-FNGQSGQILFRSNGNITRELTNITFGFRTRDANVIILHAEKEPEFLNIS 1002
Query: 1425 LLDGRVQLRFDTGSGPAVL--TSAVPVEPGQWHRLELSR-----HWRRGTLSVDGETPVL 1477
+ D R+ + +G+ +L TS V G WH + LS R + VD ETP +
Sbjct: 1003 IQDSRLFFQLQSGNSFYMLSLTSLQSVNDGTWHEVTLSMTDPLSQTSRWQMEVDNETPFV 1062
Query: 1478 GESPSGTDGLNL---DTDLFVGGVPEDQAAVALERTFVGAGLRGCIRLLDVNNQRLE--- 1531
S T LN +TD++VG D+A ++ GL+GC+ +++ L
Sbjct: 1063 -TSTIATGSLNFLKDNTDIYVG----DRAIDNIK------GLQGCLSTIEIGGIYLSYFE 1111
Query: 1532 --------------LGIGPGAATRGS-GVGECGDHPCLPNPCHGGAPCQNLEAGRFHCQC 1576
L I + G + C +PCL HGG C+++ + +HC C
Sbjct: 1112 NVHGFINKPQEEQFLKISTNSVVTGCLQLNVCNSNPCL----HGGN-CEDIYSS-YHCSC 1165
Query: 1577 PPGRVGPTCADEKSPCQPNPC-HGAAPCRVLPEGGAQCECPLGREGTFCQ 1625
P G G C C NPC HG RV C C G G C+
Sbjct: 1166 PLGWSGKHCELNIDECFSNPCIHGNCSDRV---AAYHCTCEPGYTGVNCE 1212
Score = 72.4 bits (176), Expect = 4e-12
Identities = 123/557 (22%), Positives = 193/557 (34%), Gaps = 112/557 (20%)
Query: 1333 CDSQPCFHGGTCQDWALGG--GFTCSCPAGRGGAVCEKVLGAPVPAFEGRSFL---AFPT 1387
C Q C + GTC G GF+C CP+G G++CE A +FEG FL +
Sbjct: 445 CTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEI---ATTLSFEGDGFLWVKSGSV 501
Query: 1388 LRAYHTLRLALEFRALEPQGLLLYNGNARGKDFLALALLDGRVQLRFDTGSGPAVLT-SA 1446
+AL F+ ++P LLL+ N F+ L LL G + L + VL +
Sbjct: 502 TTKGSVCNIALRFQTVQPMALLLFRSNR--DVFVKLELLSGYIHLSIQVNNQSKVLLFIS 559
Query: 1447 VPVEPGQWHRLELSRHWRRGTLSVDG--ETPVLGESPS---GTDGLNLDTDLFVGGVPED 1501
G+WH +E+ +D + + ++P+ + + F+GG+P
Sbjct: 560 HNTSDGEWHFVEVIFAEAVTLTLIDDSCKEKCIAKAPTPLESDQSICAFQNSFLGGLPVG 619
Query: 1502 QAA--VALERTF---VGAGLRGCIRLLDVNNQRLELGIGPGAATRGSGVGECGDHPCLPN 1556
+ VAL + GC++ + ++ + L ++ G C
Sbjct: 620 MTSNGVALLNFYNMPSTPSFVGCLQDIKIDWNHITLENISSGSSLNVKAGCVRKDWCESQ 679
Query: 1557 PCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQCECP 1616
PC C NL + C C GP C E
Sbjct: 680 PCQSRGRCINLWLS-YQCDCHRPYEGPNCLRE---------------------------- 710
Query: 1617 LGREGTFCQTASGQDGSGPFLADFNGFSHLELRGLHTFARDLGEKMALEVVFLARGPSGL 1676
+ GQD S ++ + T G+ ++L + PSGL
Sbjct: 711 ------YVAGRFGQDDSTGYV-------------IFTLDESYGDTISLSMFVRTLQPSGL 751
Query: 1677 LLYNGQKTD-------GKGDFVSLALRDRRLEFRYDLGKGAAVIRSREPVTLGAWTRVSL 1729
LL T +G L +L ++ L G + +SL
Sbjct: 752 LLALENSTYQYIRVWLERGRLAMLTPNSPKLVVKFVLNDGNVHL-------------ISL 798
Query: 1730 ERNGRKGALRVGDGPRVLGESPVPHTVLNLKEPLYVGGAPDFSKLARAAAVSSG-FDGAI 1788
+ K + + + LG + + +Y+GG PD + ++ G F G I
Sbjct: 799 KIKPYK--IELYQSSQNLGFISASTWKIEKGDVIYIGGLPD----KQETELNGGFFKGCI 852
Query: 1789 QLVSLGGRQL-----------LTPEHVLRQVDVTSFAGHPCTRASGHPCLNGASCVPREA 1837
Q V L + L L P VL V + C +PC NG C R
Sbjct: 853 QDVRLNNQNLEFFPNPTNNASLNP--VLVNVTQGCAGDNSC---KSNPCHNGGVCHSRWD 907
Query: 1838 AYVCLCPGGFSGPHCEK 1854
+ C CP SG CE+
Sbjct: 908 DFSCSCPALTSGKACEE 924
Score = 61.6 bits (148), Expect = 8e-09
Identities = 32/85 (37%), Positives = 35/85 (41%), Gaps = 2/85 (2%)
Query: 1552 PCLPNPCHGGAPCQNLEAGR-FHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGG 1610
PC NPC G A C N R F C+CPPG G C C N C C P
Sbjct: 73 PCFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYP 132
Query: 1611 AQCECPLGREGTFCQTASGQDGSGP 1635
C CP G G FC+ + S P
Sbjct: 133 V-CICPAGYAGRFCEIDHDECASSP 156
Score = 56.6 bits (135), Expect = 2e-07
Identities = 29/83 (34%), Positives = 37/83 (44%), Gaps = 4/83 (4%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPP--GRVGPTCADEKSPCQPNPCHGAAPCRVLP-EG 1609
CL N C + C++ C C + C + K PC NPC G+A C P E
Sbjct: 34 CLSNSCQNNSTCKDFSKDN-DCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGER 92
Query: 1610 GAQCECPLGREGTFCQTASGQDG 1632
C+CP G GT C+T G G
Sbjct: 93 SFLCKCPPGYSGTICETTIGSCG 115
Score = 55.1 bits (131), Expect = 7e-07
Identities = 112/568 (19%), Positives = 187/568 (32%), Gaps = 113/568 (19%)
Query: 1553 CLPNPCHGGAPCQNL-------------------EAGRFHCQCPPGRVGPTCADEKSPCQ 1593
C NPC C L EA + C C PG G C ++ + C
Sbjct: 343 CNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECS 402
Query: 1594 PNPCHGAAPCRVLPEGGAQCECPL------------------------------------ 1617
NPC C LP G C CP
Sbjct: 403 SNPCQNGGTCENLP-GNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQ 461
Query: 1618 -GREGTFCQTASGQDGSGPFLA---DFNGFSHLELRGLHTFARDLGEKMALEVVFLARGP 1673
G+ G C SG GS +A F G L ++ + G + + F P
Sbjct: 462 DGQHGFSCLCPSGYTGSLCEIATTLSFEGDGFLWVKSGSVTTK--GSVCNIALRFQTVQP 519
Query: 1674 SGLLLYNGQKTDGKGDFVSLALRDRRLEFRYDLGKGAAVIRSREPVTL-GAWTRVSLERN 1732
LLL+ + FV L L + + + V+ T G W V +
Sbjct: 520 MALLLFR----SNRDVFVKLELLSGYIHLSIQVNNQSKVLLFISHNTSDGEWHFVEVIFA 575
Query: 1733 GRKGALRVGDG--PRVLGESPVP---HTVLNLKEPLYVGGAPDFSKLARAAAV------- 1780
+ D + + ++P P + + ++GG P + A+
Sbjct: 576 EAVTLTLIDDSCKEKCIAKAPTPLESDQSICAFQNSFLGGLP-VGMTSNGVALLNFYNMP 634
Query: 1781 -SSGFDGAIQLVSLGGRQLLTPEHVLRQVDVTSFAGHPCTR---ASGHPCLNGASCVPRE 1836
+ F G +Q + + +T E++ + AG C R PC + C+
Sbjct: 635 STPSFVGCLQDIKIDWNH-ITLENISSGSSLNVKAG--CVRKDWCESQPCQSRGRCINLW 691
Query: 1837 AAYVCLCPGGFSGPHCEKGLVEKSAGDVDTLAFDGRTFVE-YLNAVTES--EKALQSNHF 1893
+Y C C + GP+C + V G D+ + T E Y + ++ S + LQ +
Sbjct: 692 LSYQCDCHRPYEGPNCLREYVAGRFGQDDSTGYVIFTLDESYGDTISLSMFVRTLQPSGL 751
Query: 1894 ELSLRTEATQGLVLWSGKATERADYVALAIVDGHLQLSYNLGSQPVVLRSTVPVNTNRWL 1953
L+L Q + +W ER L L + + L V L S L
Sbjct: 752 LLALENSTYQYIRVW----LERGRLAMLTPNSPKLVVKFVLNDGNVHLIS---------L 798
Query: 1954 RVVAHREQREGSLQVGNEAPVTGSSPLGATQLDTDGALWLGGLPELPVGPALPKAYGTGF 2013
++ ++ +++ + G +++ +++GGLP+ + G F
Sbjct: 799 KIKPYK------IELYQSSQNLGFISASTWKIEKGDVIYIGGLPD----KQETELNGGFF 848
Query: 2014 VGCLRDVVVGRHPLHLLEDAVTKPELRP 2041
GC++DV + L + L P
Sbjct: 849 KGCIQDVRLNNQNLEFFPNPTNNASLNP 876
Score = 52.4 bits (124), Expect = 5e-06
Identities = 107/484 (22%), Positives = 147/484 (30%), Gaps = 106/484 (21%)
Query: 461 CDQAPSPCLGVQCAFGATCAVKNGQAACECLQACSSLYDPVCGSDGVTYGSACELEATAC 520
C++ + CL C +TC + C C ++L + + C+ AT
Sbjct: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
Query: 521 TLGREIQVARKGPCDRCGQCRFGALCEAETGRC---VCPSECVALAQPVCGSDGHTYPSE 577
E R C +C G +CE G C C + P+ YP
Sbjct: 87 NTPGE----RSFLC-KCPPGYSGTICETTIGSCGKNSCQHGGICHQDPI-------YP-- 132
Query: 578 CMLHVHACTHQISLHVASAGPCETCGDAVCAFGAVCSAG----QCVCPRCEHPPPGPVCG 633
V C + E C + C GAVC G C C PG
Sbjct: 133 ----VCICPAGYAGRFCEIDHDE-CASSPCQNGAVCQDGIDGYSCFC------VPG---- 177
Query: 634 SDGVTYGSACELREAACLQQTQIEEARA-GPCEQAECGSGGSGSGEDGDCEQELCRQRGG 692
G C+L C EA + C + SG + + E + C
Sbjct: 178 ----YQGRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEIDEC----- 228
Query: 693 IWDEDSEDGPCVCDFSCQSVPGSPVCGSDGVTYSTECELKKARCESQ----RGLYVAAQG 748
W + PC+ +CQ G+ C CEL C SQ GL V +
Sbjct: 229 -WSQ-----PCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQPCLHGGLCVDGEN 282
Query: 749 A----CRGPTF--APLPPVAPLHCAQTPYGCCQDNITAARGVGLAGCPSACQCNPHGSYG 802
C G F + PL C P C +N T V C C P G G
Sbjct: 283 RYSCNCTGSGFTGTHCETLMPL-CWSKP---CHNNATCEDSVD----NYTCHCWP-GYTG 333
Query: 803 GTCDPATGQCSCRPGVGGLRCDR--CEPGFWNFRGIVTDGRSGCTPCSCDPQGAVRDDCE 860
C+ +C+ P C E + G+ P S E
Sbjct: 334 AQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGL---------PSSFSYH-------E 377
Query: 861 QMTGLCSCKPGVAGPKCGQCPDGRALGPAGCEADASAPATCAEMRCEFGARCVEESGSAH 920
+C C+PG G CE D + C+ C+ G C G+
Sbjct: 378 ASGYVCICQPGFTG--------------IHCEEDVN---ECSSNPCQNGGTCENLPGNYT 420
Query: 921 CVCP 924
C CP
Sbjct: 421 CHCP 424
Score = 52.0 bits (123), Expect = 6e-06
Identities = 81/356 (22%), Positives = 111/356 (31%), Gaps = 71/356 (19%)
Query: 228 CSQQRRIRLLSRGPCGSRDPCSNVTCSFGSTCARSADGLTASCLCPATCRGAPEGTVCGS 287
CS L + +DPC + C +TC + + C CP G T GS
Sbjct: 54 CSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIGS 113
Query: 288 DGADYPGECQLLRRACARQENVFKKFDGPCDPCQGALPDPSRSCRVNPRTRRPEMLLRPE 347
G + CQ Q+ ++ P C R C ++
Sbjct: 114 CGKN---SCQ--HGGICHQDPIY-----PVCICPAGY--AGRFCEIDHD--------ECA 153
Query: 348 SCPARQAPVCGDDGVTYENDCVMGRSGAARGLLLQKVRSGQCQGRDQC-PEPCRFNAVCL 406
S P + VC D Y CV G G L + D+C +PC+ A CL
Sbjct: 154 SSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEV-----------DECASDPCKNEATCL 202
Query: 407 SRRGRPRCSCDR----VTC----DGAYRPVCAQDGRTYDSDCWRQQAECRQQRAIPSKHQ 458
+ GR C C V C D + C +G T +C P
Sbjct: 203 NEIGRYTCICPHNYSGVNCELEIDECWSQPCL-NGATCQDALGAYFCDC-----APGFLG 256
Query: 459 GPCDQAPSPCLGVQCAFGATCAVKNGQAACECLQA------CSSLYDPVCGSDGVTYGSA 512
C+ C C G C + +C C + C +L P+C S +
Sbjct: 257 DHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLM-PLCWSKPCHNNAT 315
Query: 513 CELEATACTLGREIQVARKGPCDRCGQCRFGALCEAETGRC---VCPS--ECVALA 563
CE T C GA CE + C C S ECV L+
Sbjct: 316 CEDSVDNYTC-------------HCWPGYTGAQCEIDLNECNSNPCQSNGECVELS 358
Score = 50.1 bits (118), Expect = 2e-05
Identities = 29/85 (34%), Positives = 36/85 (42%), Gaps = 2/85 (2%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQ 1612
C +PC A C N E GR+ C CP G C E C PC A C+ G
Sbjct: 190 CASDPCKNEATCLN-EIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQD-ALGAYF 247
Query: 1613 CECPLGREGTFCQTASGQDGSGPFL 1637
C+C G G C+ + + S P L
Sbjct: 248 CDCAPGFLGDHCELNTDECASQPCL 272
Score = 48.9 bits (115), Expect = 5e-05
Identities = 31/89 (34%), Positives = 38/89 (42%), Gaps = 3/89 (3%)
Query: 1550 DHP-CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPE 1608
DH C +PC GA CQ+ G + C C PG G C E C +PC A C +
Sbjct: 148 DHDECASSPCQNGAVCQDGIDG-YSCFCVPGYQGRHCDLEVDECASDPCKNEATC-LNEI 205
Query: 1609 GGAQCECPLGREGTFCQTASGQDGSGPFL 1637
G C CP G C+ + S P L
Sbjct: 206 GRYTCICPHNYSGVNCELEIDECWSQPCL 234
Score = 48.5 bits (114), Expect = 7e-05
Identities = 85/386 (22%), Positives = 117/386 (30%), Gaps = 87/386 (22%)
Query: 170 DACRGMLCGFGAVCEPNAEGPGRASCVCKKSPCPSVVAPVCGSDASTYSNECELQRAQCS 229
D C C GAVC+ +G SC C C+L+ +C+
Sbjct: 150 DECASSPCQNGAVCQDGIDG---YSCFCVPG---------------YQGRHCDLEVDECA 191
Query: 230 QQRRIRLLSRGPCGSRDPCSNVTCSFGSTCARSADGLTAS----------CLCPATCRGA 279
PC + C N + C + G+ CL ATC+ A
Sbjct: 192 SD---------PCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDA 242
Query: 280 PEGTVCGSDGADYPGECQLLRRACARQENVFKKFDGPC---DPCQGALPDPSRSCRVNPR 336
C C+L CA Q PC C S +C +
Sbjct: 243 LGAYFCDCAPGFLGDHCELNTDECASQ---------PCLHGGLCVDGENRYSCNCTGSGF 293
Query: 337 TRRPEMLLRPE--SCPARQAPVCGDDGVTYENDCVMGRSGAARGLLLQKVRSGQCQGRDQ 394
T L P S P C D Y C G +GA + L + S CQ +
Sbjct: 294 TGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGE 353
Query: 395 CPE-------------PCRFN------AVCLSRRGRPRCSCDRVTCDGAYRPVCAQDGRT 435
C E P F+ VC+ + G C+ + + P Q+G T
Sbjct: 354 CVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNP--CQNGGT 411
Query: 436 YDSDCWRQQAECRQQRAIPSKHQG-PCDQAPSPCLGVQCAFGATCA--VKNGQAACECLQ 492
++ C + + G C C QC TC ++GQ CL
Sbjct: 412 CENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCL- 470
Query: 493 ACSSLYDPVCGSDGVTYGSACELEAT 518
C S Y GS CE+ T
Sbjct: 471 -CPSGYT----------GSLCEIATT 485
Score = 47.4 bits (111), Expect = 1e-04
Identities = 27/75 (36%), Positives = 31/75 (41%), Gaps = 3/75 (4%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQ 1612
C PC GA CQ+ G + C C PG +G C C PC C V E
Sbjct: 228 CWSQPCLNGATCQDA-LGAYFCDCAPGFLGDHCELNTDECASQPCLHGGLC-VDGENRYS 285
Query: 1613 CECP-LGREGTFCQT 1626
C C G GT C+T
Sbjct: 286 CNCTGSGFTGTHCET 300
Score = 45.4 bits (106), Expect = 6e-04
Identities = 26/102 (25%), Positives = 33/102 (32%), Gaps = 20/102 (19%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPE---- 1608
C PCH A C++ + C C PG G C + + C NPC C L
Sbjct: 305 CWSKPCHNNATCED-SVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQY 363
Query: 1609 ---------------GGAQCECPLGREGTFCQTASGQDGSGP 1635
G C C G G C+ + S P
Sbjct: 364 GRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNP 405
Score = 42.0 bits (97), Expect = 0.006
Identities = 17/29 (58%), Positives = 18/29 (62%)
Query: 1825 PCLNGASCVPREAAYVCLCPGGFSGPHCE 1853
PCLNGA+C AY C C GF G HCE
Sbjct: 232 PCLNGATCQDALGAYFCDCAPGFLGDHCE 260
Score = 40.8 bits (94), Expect = 0.014
Identities = 16/41 (39%), Positives = 20/41 (48%)
Query: 1332 PCDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEKVLGA 1372
PC S PC TC + F C CP G G +CE +G+
Sbjct: 73 PCFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIGS 113
Score = 40.0 bits (92), Expect = 0.023
Identities = 50/198 (25%), Positives = 61/198 (30%), Gaps = 40/198 (20%)
Query: 793 CQCNP-HGSYGGTCDPATGQ----CSCRPGVGGLRCDR----CEPGFWNFRGIVTDGRSG 843
C NP GS TC G+ C C PG G C+ C GI +
Sbjct: 74 CFSNPCQGS--ATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICH--QDP 129
Query: 844 CTPCSCDPQGAVRDDCEQMTGLCSCKPGVAGPKCGQCPDGRAL----GPAGCEADASAPA 899
P P G CE C+ P G C DG + G G D
Sbjct: 130 IYPVCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDE 189
Query: 900 TCAEMRCEFGARCVEESGSAHCVCPM----------------------LTCPEANATKVC 937
CA C+ A C+ E G C+CP TC +A C
Sbjct: 190 -CASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFC 248
Query: 938 GSDGVTYGNECQLKTIAC 955
G+ C+L T C
Sbjct: 249 DCAPGFLGDHCELNTDEC 266
Score = 40.0 bits (92), Expect = 0.023
Identities = 20/46 (43%), Positives = 23/46 (50%), Gaps = 5/46 (10%)
Query: 1813 FAGHPCT----RASGHPCLNGASCVPREAAYVCLCPG-GFSGPHCE 1853
F G C + PCL+G CV E Y C C G GF+G HCE
Sbjct: 254 FLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCE 299
Score = 40.0 bits (92), Expect = 0.023
Identities = 29/90 (32%), Positives = 34/90 (37%), Gaps = 8/90 (8%)
Query: 1547 ECGDHPCLPNPCHGGAPCQNLEAGRFHCQCP-PGRVGPTCADEKSPCQPNPCHGAAPCRV 1605
EC PCL HGG C + E R+ C C G G C C PCH A C
Sbjct: 265 ECASQPCL----HGGL-CVDGE-NRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCED 318
Query: 1606 LPEGGAQCECPLGREGTFCQTASGQDGSGP 1635
+ C C G G C+ + S P
Sbjct: 319 SVD-NYTCHCWPGYTGAQCEIDLNECNSNP 347
Score = 39.3 bits (90), Expect = 0.040
Identities = 14/31 (45%), Positives = 18/31 (58%)
Query: 1824 HPCLNGASCVPREAAYVCLCPGGFSGPHCEK 1854
H C NGA+C+ Y CLC G F+G C +
Sbjct: 1221 HQCANGATCISHTNGYSCLCFGNFTGKFCRQ 1251
Score = 38.9 bits (89), Expect = 0.052
Identities = 40/192 (20%), Positives = 60/192 (31%), Gaps = 56/192 (29%)
Query: 786 LAGCPSACQCNPHGS-YGGTCDP--ATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRS 842
+ GC CN + +GG C+ ++ CSC G G C+
Sbjct: 1134 VTGCLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCEL----------------- 1176
Query: 843 GCTPCSCDPQGAVRDDCEQMTGL--CSCKPGVAGPKCGQCPDGRALGPAGCEADASAPAT 900
C +P + +C C+C+PG G CE D
Sbjct: 1177 NIDECFSNP--CIHGNCSDRVAAYHCTCEPGYTG--------------VNCEVDID---N 1217
Query: 901 CAEMRCEFGARCVEESGSAHCVC--------------PMLTCPEANATKVCGSDGVTYGN 946
C +C GA C+ + C+C P C C + G
Sbjct: 1218 CQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEF 1277
Query: 947 ECQLKTIACRQG 958
+ +LK + CR G
Sbjct: 1278 QTELKCM-CRPG 1288
Score = 38.1 bits (87), Expect = 0.089
Identities = 16/48 (33%), Positives = 23/48 (47%), Gaps = 4/48 (8%)
Query: 1810 VTSFAGHPCT----RASGHPCLNGASCVPREAAYVCLCPGGFSGPHCE 1853
V + G C + PC N A+C+ Y C+CP +SG +CE
Sbjct: 175 VPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCE 222
Score = 38.1 bits (87), Expect = 0.089
Identities = 20/74 (27%), Positives = 27/74 (36%), Gaps = 2/74 (2%)
Query: 1558 CHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQCECPL 1617
C+ G C + C C PG G C + C +PC C+ L QC C +
Sbjct: 1268 CYNGGNCTEFQT-ELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDL-LNKFQCLCDV 1325
Query: 1618 GREGTFCQTASGQD 1631
G C+ D
Sbjct: 1326 AFAGERCEVDLADD 1339
Score = 37.4 bits (85), Expect = 0.15
Identities = 20/35 (57%), Positives = 21/35 (60%), Gaps = 2/35 (5%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCE 1367
C SQPC +G TCQD ALG F C C G G CE
Sbjct: 228 CWSQPCLNGATCQD-ALGAYF-CDCAPGFLGDHCE 260
Score = 37.0 bits (84), Expect = 0.20
Identities = 15/32 (46%), Positives = 21/32 (65%), Gaps = 2/32 (6%)
Query: 1824 HPCLNGASCV--PREAAYVCLCPGGFSGPHCE 1853
+PC A+CV P E +++C CP G+SG CE
Sbjct: 77 NPCQGSATCVNTPGERSFLCKCPPGYSGTICE 108
Score = 36.6 bits (83), Expect = 0.26
Identities = 18/58 (31%), Positives = 25/58 (43%), Gaps = 4/58 (6%)
Query: 1813 FAGHPCTR----ASGHPCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVEKSAGDVDT 1866
F G C + + PC+NG C + CLC F+G CE L + D+ T
Sbjct: 1289 FTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLADDLISDIFT 1346
Score = 35.4 bits (80), Expect = 0.58
Identities = 16/45 (35%), Positives = 20/45 (44%), Gaps = 4/45 (8%)
Query: 1813 FAGHPCT----RASGHPCLNGASCVPREAAYVCLCPGGFSGPHCE 1853
+AG C + PC NGA C Y C C G+ G HC+
Sbjct: 140 YAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCD 184
Score = 34.7 bits (78), Expect = 0.98
Identities = 13/33 (39%), Positives = 18/33 (54%)
Query: 1826 CLNGASCVPREAAYVCLCPGGFSGPHCEKGLVE 1858
C NG +C + C+C GF+G CEK + E
Sbjct: 1268 CYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDE 1300
Score = 34.3 bits (77), Expect = 1.3
Identities = 16/39 (41%), Positives = 22/39 (56%), Gaps = 3/39 (7%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCP-AGRGGAVCEKVL 1370
C SQPC HGG C D ++C+C +G G CE ++
Sbjct: 266 CASQPCLHGGLCVDGE--NRYSCNCTGSGFTGTHCETLM 302
Score = 33.9 bits (76), Expect = 1.7
Identities = 16/35 (45%), Positives = 17/35 (48%), Gaps = 2/35 (5%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCE 1367
C S PC +GG CQD L F C C G CE
Sbjct: 1301 CASDPCVNGGLCQD--LLNKFQCLCDVAFAGERCE 1333
Score = 33.5 bits (75), Expect = 2.2
Identities = 15/35 (42%), Positives = 19/35 (54%), Gaps = 2/35 (5%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCE 1367
C S+PC + TC+D +TC C G GA CE
Sbjct: 305 CWSKPCHNNATCEDSV--DNYTCHCWPGYTGAQCE 337
Score = 32.3 bits (72), Expect = 4.9
Identities = 14/35 (40%), Positives = 18/35 (51%), Gaps = 2/35 (5%)
Query: 1333 CDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCE 1367
C S PC +G CQD G++C C G G C+
Sbjct: 152 CASSPCQNGAVCQDGI--DGYSCFCVPGYQGRHCD 184
Score = 31.6 bits (70), Expect = 8.3
Identities = 26/93 (27%), Positives = 31/93 (33%), Gaps = 5/93 (5%)
Query: 1275 TASRLPSSAVTPRAPHPSHTSQPVAKTTAAPTTRRPPTTAPSRVPGRRPPAPQQPPKPCD 1334
TA+ L + P S+ Q A P R P PG + C
Sbjct: 59 TANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCP---PGYSGTICETTIGSCG 115
Query: 1335 SQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCE 1367
C HGG C + C CPAG G CE
Sbjct: 116 KNSCQHGGICHQDPIYP--VCICPAGYAGRFCE 146
Score = 31.6 bits (70), Expect = 8.3
Identities = 14/34 (41%), Positives = 17/34 (50%)
Query: 1825 PCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVE 1858
PC N A+C Y C C G++G CE L E
Sbjct: 309 PCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNE 342
>gi|122937343 platelet endothelial aggregation receptor 1 [Homo
sapiens]
Length = 1037
Score = 108 bits (271), Expect = 4e-23
Identities = 177/715 (24%), Positives = 231/715 (32%), Gaps = 200/715 (27%)
Query: 390 QGRDQCPEPCRF------NAVCLSRRGRPRCSCDRVTCDGAYRPVCAQD---GRTY-DSD 439
+G CP+P V R R +C G P+CAQ+ GR +
Sbjct: 60 EGPHTCPQPTVVYRTVYRQVVKTDHRQRLQCCHGFYESRGFCVPLCAQECVHGRCVAPNQ 119
Query: 440 C-----WRQQAECRQQRAIPSKHQGPCDQAPSPCLGVQCAFGATCAVKNGQAAC------ 488
C WR +C + A P CD+ PC C ++C K+G +C
Sbjct: 120 CQCVPGWRGD-DCSSECA-PGMWGPQCDK---PC---SCGNNSSCDPKSGVCSCPSGLQP 171
Query: 489 -ECLQACS-SLYDPVCGSDGVTYGSACELEATACTLGREIQVARKGP-CD-RCGQ----- 539
CLQ C+ Y P C +G+ C+ + AC E R GP CD C Q
Sbjct: 172 PNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGACFCPAE----RTGPSCDVSCSQGTSGF 227
Query: 540 -------CRFGALCEAETGRCVCPSECVA-LAQPVC--GSDGHTYPSECMLHVHA----- 584
C+ G + + G C CP + + C G G EC H
Sbjct: 228 FCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGLCDRF 287
Query: 585 --------------CTHQISLHVASAGPCETCGDAVCAFGAVCSAGQCVCPRCEHPPPGP 630
C + + ETC CA A C C CEH G
Sbjct: 288 TGQCRCAPGYTGDRCREECPVGRFGQDCAETCD---CAPDARCFPANGAC-LCEHGFTGD 343
Query: 631 VCGS----DGVTYGSACELREAACLQQTQIEEARAGPCEQAECGSGGSGSGEDGDCEQEL 686
C DG YG +C+ + + G C C G +G + C Q+
Sbjct: 344 RCTDRLCPDGF-YGLSCQAPCTCDREHSLSCHPMNGECS---CLPGWAGLHCNESCPQDT 399
Query: 687 ----CRQR-----GGIWDEDSEDGPCVCDFSCQSVPGSPVCGSD--GVTYSTECELKKA- 734
C++ GG+ S G C C + +C D GV S C + A
Sbjct: 400 HGPGCQEHCLCLHGGVCQATS--GLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAI 457
Query: 735 RCESQRGLYVAAQGACRGPTFAPLPPV-------APLHCAQTPY-----GCC-------- 774
C G V +G RG P PP A CA G C
Sbjct: 458 ACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVCSPQTGACTCTPGWHG 517
Query: 775 -QDNITAARGVGLAGCPSACQCN---------------------------PHGSYG---- 802
+ +G GC S C C+ P G +G
Sbjct: 518 AHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCS 577
Query: 803 --------GTCDPATGQCSCRPGVGGLRCDR-CEPGFWNFRGIVTDGRSGCTPCSCDPQG 853
GTC P G C C PG G C R C+PG + R C PC C
Sbjct: 578 NTCTCKNGGTCLPENGNCVCAPGFRGPSCQRSCQPGRYGKR---------CVPCKC---- 624
Query: 854 AVRDDCEQMTGLCSCKPGVAGPKCGQ-CPDGRALGPAGCEADASAPATCAEMRCEFGARC 912
A C G C C G GP C Q CP G + TC +C G C
Sbjct: 625 ANHSFCHPSNGTCYCLAGWTGPDCSQPCPPG--------HWGENCAQTC---QCHHGGTC 673
Query: 913 VEESGSAHCVCP--------MLTCP----EANATKVCGSDGVTYGNECQLKTIAC 955
+ GS C+CP + CP AN ++ C G +C +T AC
Sbjct: 674 HPQDGS--CICPLGWTGHHCLEGCPLGTFGANCSQPCQCGP---GEKCHPETGAC 723
Score = 97.1 bits (240), Expect = 2e-19
Identities = 182/761 (23%), Positives = 235/761 (30%), Gaps = 223/761 (29%)
Query: 190 PGRASCVCKKSPCPSVVAPVCGSDASTYSNE-CELQRAQCSQQRRIRLLSRGPCGSRDPC 248
PG C P + P C S +N C+ + CS ++ P PC
Sbjct: 124 PGWRGDDCSSECAPGMWGPQCDKPCSCGNNSSCDPKSGVCSCPSGLQ-----PPNCLQPC 178
Query: 249 S----NVTCSFGSTC-ARSADGLTASCLCPATCRGAPEGTVC--GSDGADYPGECQLLRR 301
+ C F C D T +C CPA G C G+ G P
Sbjct: 179 TPGYYGPACQFRCQCHGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPST-----H 233
Query: 302 ACARQENVFKKFDGPCD------------PCQGALPDPSRSCRVNPRTRRPEMLLRPESC 349
+C + VF+ G C PC P+ S + C
Sbjct: 234 SC-QNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCS----------------QEC 276
Query: 350 PARQAPVCGDDGVTYENDCVMGRSGAARGLLLQKVRSGQCQGRDQCPEPC---RFNAVCL 406
+C D T + C G +G D+C E C RF C
Sbjct: 277 RCHNGGLC--DRFTGQCRCAPGYTG------------------DRCREECPVGRFGQDCA 316
Query: 407 SRRGRPRCSCDRVTCDGAYRPVCAQDGRTYDSD--CWRQQAECRQQ---RAIPSKHQGPC 461
TCD CA D R + ++ C + + R P G
Sbjct: 317 E------------TCD------CAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLS 358
Query: 462 DQAPSPCLGVQCAFGATCAVKNGQAACECLQACSSLY-DPVCGSDGVTYGSACELEATAC 520
QAP C +C NG+ C CL + L+ + C D T+G C+
Sbjct: 359 CQAPCTC---DREHSLSCHPMNGE--CSCLPGWAGLHCNESCPQD--THGPGCQ------ 405
Query: 521 TLGREIQVARKGPCDRCGQCRFGALCEAETGRCVCPSECVALAQPVCGSDGHTYPSECML 580
+ C C G +C+A +G C C + G+T P
Sbjct: 406 --------------EHC-LCLHGGVCQATSGLCQC-------------APGYTGP----- 432
Query: 581 HVHACTHQISLHVASAGPCETCG-----DAVCAFGAVCSA--GQCVCPR------CEHPP 627
H AS P +T G C CS G+CVC C P
Sbjct: 433 -----------HCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPC 481
Query: 628 PGPVCGSDGVTYGSACEL-REAACLQQTQIEEARAG----PCEQAECGSGGSGSGEDGDC 682
P G+ G + ++C+ EA C QT G C Q C G G G C
Sbjct: 482 PP---GTWGFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHC-QLPCPKGQFGEGCASRC 537
Query: 683 EQELCRQRGGIWDEDSEDGPCVCDFSCQSVPGSPVC--GSDGVTYSTECELKKA-RCESQ 739
+ C G D G C C C G GV S C K C +
Sbjct: 538 D---CDHSDGC---DPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPE 591
Query: 740 RGLYVAAQGACRGPTFAPL-------PPVAPLHCAQTPYGCCQDNITAARGVGLAG---- 788
G V A G RGP+ P CA + C N T G G
Sbjct: 592 NGNCVCAPGF-RGPSCQRSCQPGRYGKRCVPCKCANHSF-CHPSNGTCYCLAGWTGPDCS 649
Query: 789 -----------CPSACQCNPHGSYGGTCDPATGQCSCRPGVGGLRC-DRCEPGFWNFRGI 836
C CQC+ +GGTC P G C C G G C + C G
Sbjct: 650 QPCPPGHWGENCAQTCQCH----HGGTCHPQDGSCICPLGWTGHHCLEGCPLG------- 698
Query: 837 VTDGRSGCTPCSCDPQGAVRDDCEQMTGLCSCKPGVAGPKC 877
T G + PC C P + C TG C C PG +G C
Sbjct: 699 -TFGANCSQPCQCGPG----EKCHPETGACVCPPGHSGAPC 734
Score = 49.7 bits (117), Expect = 3e-05
Identities = 93/401 (23%), Positives = 113/401 (28%), Gaps = 103/401 (25%)
Query: 176 LCGFGAVCEPNAEGPGRASCVCKKSPCPSVVAPVCGS--DASTYSNECELQRAQCSQQRR 233
LC G VC+ + C C P P C S TY C A+CS +
Sbjct: 409 LCLHGGVCQATS-----GLCQC----APGYTGPHCASLCPPDTYGVNCS---ARCSCENA 456
Query: 234 IRLLS-RGPCGSRDPCSNVTCSFGSTCARSADGLTASCLCPATCRGAPEGTVCGSDGADY 292
I G C ++ CS ASC C +P+ C +
Sbjct: 457 IACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVCSPQTGACTCTPGWH 516
Query: 293 PGECQLLRRACARQENVFKKFDGPCDPCQGALPDPSR-SCRVNPRTRRPEMLLRPESCPA 351
CQL E + D CD G P R C+ R + SCP
Sbjct: 517 GAHCQLPCPKGQFGEGCASRCD--CDHSDGCDPVHGRCQCQAGWMGARCHL-----SCPE 569
Query: 352 RQAPVCGDDGVTYENDCVMGRSGAARGLLLQKVRSGQCQGRDQCPEPCRFNAVCLSRRGR 411
G GV N C G PE N C+ G
Sbjct: 570 ------GLWGVNCSNTCTCKNGGTC------------------LPE----NGNCVCAPGF 601
Query: 412 PRCSCDRVTCDGAYRPVCAQDGRTYDSDCWRQQAECRQ---------QRAIPSKHQGPCD 462
SC R G Y C S C C + P H G +
Sbjct: 602 RGPSCQRSCQPGRYGKRCVPCKCANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHWG--E 659
Query: 463 QAPSPCLGVQCAFGATCAVKNGQAAC-------ECLQACSSLYDPVCGSDGVTYGSACEL 515
C QC G TC ++G C CL+ C T+G+ C
Sbjct: 660 NCAQTC---QCHHGGTCHPQDGSCICPLGWTGHHCLEGCPL----------GTFGANCSQ 706
Query: 516 EATACTLGREIQVARKGPCDRCGQCRFGALCEAETGRCVCP 556
PC QC G C ETG CVCP
Sbjct: 707 -----------------PC----QCGPGEKCHPETGACVCP 726
Score = 41.6 bits (96), Expect = 0.008
Identities = 33/97 (34%), Positives = 36/97 (37%), Gaps = 23/97 (23%)
Query: 1550 DHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPN----------PCHG 1599
D PC C + C C CP G P C PC P CHG
Sbjct: 145 DKPC---SCGNNSSCDPKSGV---CSCPSGLQPPNCL---QPCTPGYYGPACQFRCQCHG 195
Query: 1600 AAPCRVLPEGGAQCECPLGREGTFCQTASGQDGSGPF 1636
APC P+ GA C CP R G C + Q SG F
Sbjct: 196 -APCD--PQTGA-CFCPAERTGPSCDVSCSQGTSGFF 228
Score = 38.1 bits (87), Expect = 0.089
Identities = 32/92 (34%), Positives = 38/92 (41%), Gaps = 15/92 (16%)
Query: 1535 GPGAATRGSGVGECGDHPCLPNPCHGGAPCQNLEAG-RFHCQCPPGRVGPTCADEKSPCQ 1593
G G A+R +C DH +P HG CQ G R H CP G G C++ +
Sbjct: 530 GEGCASRC----DC-DHSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCT--- 581
Query: 1594 PNPCHGAAPCRVLPEGGAQCECPLGREGTFCQ 1625
C C LPE G C C G G CQ
Sbjct: 582 ---CKNGGTC--LPENG-NCVCAPGFRGPSCQ 607
Score = 36.6 bits (83), Expect = 0.26
Identities = 29/93 (31%), Positives = 34/93 (36%), Gaps = 25/93 (26%)
Query: 1546 GECGDHPCLPNPCHGGAPCQNLEAGRF--------HCQ--CPPGRVGPTCADEKSPCQPN 1595
G G++ CH G C + HC CP G G C+ PCQ
Sbjct: 655 GHWGENCAQTCQCHHGGTCHPQDGSCICPLGWTGHHCLEGCPLGTFGANCS---QPCQCG 711
Query: 1596 P---CHGAAPCRVLPEGGAQCECPLGREGTFCQ 1625
P CH PE GA C CP G G C+
Sbjct: 712 PGEKCH--------PETGA-CVCPPGHSGAPCR 735
Score = 36.2 bits (82), Expect = 0.34
Identities = 21/49 (42%), Positives = 23/49 (46%), Gaps = 9/49 (18%)
Query: 1576 CPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQCECPLGREGTFC 1624
CPPG G CA CQ CH C P+ G+ C CPLG G C
Sbjct: 652 CPPGHWGENCA---QTCQ---CHHGGTCH--PQDGS-CICPLGWTGHHC 691
Score = 35.4 bits (80), Expect = 0.58
Identities = 27/84 (32%), Positives = 31/84 (36%), Gaps = 12/84 (14%)
Query: 1558 CHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNP---CHGAAPCR---VLPEGGA 1611
CHG APC C CP R GP+C + S Q C C+ V
Sbjct: 193 CHG-APCDPQTGA---CFCPAERTGPSC--DVSCSQGTSGFFCPSTHSCQNGGVFQTPQG 246
Query: 1612 QCECPLGREGTFCQTASGQDGSGP 1635
C CP G GT C + GP
Sbjct: 247 SCSCPPGWMGTICSLPCPEGFHGP 270
Score = 34.7 bits (78), Expect = 0.98
Identities = 32/127 (25%), Positives = 40/127 (31%), Gaps = 51/127 (40%)
Query: 1558 CHGGAPCQNLEAGRFHC-----------QCPPGRVGPTCADEKSPCQPN----PCHGAAP 1602
CH G C G+ C +CP GR G CA E C P+ P +GA
Sbjct: 278 CHNGGLCDRF-TGQCRCAPGYTGDRCREECPVGRFGQDCA-ETCDCAPDARCFPANGACL 335
Query: 1603 C-----------RVLPEG-----------------------GAQCECPLGREGTFCQTAS 1628
C R+ P+G +C C G G C +
Sbjct: 336 CEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNESC 395
Query: 1629 GQDGSGP 1635
QD GP
Sbjct: 396 PQDTHGP 402
Score = 33.9 bits (76), Expect = 1.7
Identities = 28/90 (31%), Positives = 34/90 (37%), Gaps = 26/90 (28%)
Query: 1558 CHGGAPCQN---LEAGRFHCQCPPGRVGPTCADEKSPC----------QPNPCHG----- 1599
C CQN + + C CPPG +G C+ PC Q CH
Sbjct: 229 CPSTHSCQNGGVFQTPQGSCSCPPGWMGTICS---LPCPEGFHGPNCSQECRCHNGGLCD 285
Query: 1600 --AAPCRVLP-EGGAQC--ECPLGREGTFC 1624
CR P G +C ECP+GR G C
Sbjct: 286 RFTGQCRCAPGYTGDRCREECPVGRFGQDC 315
Score = 33.5 bits (75), Expect = 2.2
Identities = 33/108 (30%), Positives = 37/108 (34%), Gaps = 33/108 (30%)
Query: 1540 TRGSGVGECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPN---- 1595
T G G C +H CL C G CQ A CQC PG GP CA S C P+
Sbjct: 399 THGPG---CQEH-CL---CLHGGVCQ---ATSGLCQCAPGYTGPHCA---SLCPPDTYGV 445
Query: 1596 ------PCHGAAPCRVL----------PEGGAQCECPLGREGTFCQTA 1627
C A C + G CP G G C +
Sbjct: 446 NCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNAS 493
Score = 33.1 bits (74), Expect = 2.9
Identities = 12/29 (41%), Positives = 17/29 (58%), Gaps = 2/29 (6%)
Query: 1826 CLNGASCVPREAAYVCLCPGGFSGPHCEK 1854
C NG +C+P C+C GF GP C++
Sbjct: 582 CKNGGTCLPENGN--CVCAPGFRGPSCQR 608
Score = 33.1 bits (74), Expect = 2.9
Identities = 12/30 (40%), Positives = 21/30 (70%), Gaps = 2/30 (6%)
Query: 1826 CLNGASCVPREAAYVCLCPGGFSGPHCEKG 1855
C +G +C P++ + C+CP G++G HC +G
Sbjct: 667 CHHGGTCHPQDGS--CICPLGWTGHHCLEG 694
Score = 31.6 bits (70), Expect = 8.3
Identities = 24/79 (30%), Positives = 30/79 (37%), Gaps = 16/79 (20%)
Query: 1553 CLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSP------C-QPNPCHGAAPCRV 1605
C HG N CQC PG G C+ E +P C +P C + C
Sbjct: 105 CAQECVHGRCVAPN------QCQCVPGWRGDDCSSECAPGMWGPQCDKPCSCGNNSSCD- 157
Query: 1606 LPEGGAQCECPLGREGTFC 1624
P+ G C CP G + C
Sbjct: 158 -PKSGV-CSCPSGLQPPNC 174
Score = 31.6 bits (70), Expect = 8.3
Identities = 14/32 (43%), Positives = 15/32 (46%), Gaps = 3/32 (9%)
Query: 1574 CQCPPGRVGPTCADEKSPCQPNPCHGAAPCRV 1605
CQC PG C E C P H APCR+
Sbjct: 708 CQCGPGE---KCHPETGACVCPPGHSGAPCRI 736
>gi|38788416 laminin, alpha 1 precursor [Homo sapiens]
Length = 3075
Score = 108 bits (270), Expect = 5e-23
Identities = 129/477 (27%), Positives = 163/477 (34%), Gaps = 111/477 (23%)
Query: 488 CECLQ-----ACSSLYDPVCGSDGVTYGSACELEATACTL-GREIQVARKGPCDRCGQCR 541
CEC Q +C S DG+ +G C+ C G + G C C
Sbjct: 709 CECPQGYTGTSCESCLSGYYRVDGILFGGICQ----PCECHGHAAECNVHGVCIACAHNT 764
Query: 542 FGALCEAETGRCVCPSECVA--LAQPVCGSDGHTYPSECMLHVHACTHQISLHVA----- 594
G CE +C+ +P G+ G P C L + + + H+
Sbjct: 765 TGVHCE----------QCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEV 814
Query: 595 ---------SAGPCETCGDAVCAFGAVC--SAGQCVCPRCEHPPPGPVCGSD-------- 635
S CE C D V S C C P C S
Sbjct: 815 VCDWCAPGYSGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCL 874
Query: 636 GVTYGSACELREAACLQQTQIEEARAGPCEQAECGSGGSGSG----EDG--DCEQELCRQ 689
G T G+ CE C + A C EC GS S E G DC+ + Q
Sbjct: 875 GNTDGAHCE----RCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPNVTGQ 930
Query: 690 R-----GGIWDEDSEDG--PCVCDFSCQSVPGSPVCGSDGVTYSTECE----LKKARCES 738
+ G + DS G PC C SV GS SDG T +C + RC+
Sbjct: 931 QCDQCLHGYYGLDSGHGCRPCNC-----SVAGSV---SDGCTDEGQCHCVPGVAGKRCDR 982
Query: 739 -QRGLYVAAQGACRGPTFAPLPP----------VAPLHCAQTPYGCCQDNITAARGVGLA 787
G Y G+C P P V P H C+D
Sbjct: 983 CAHGFYAYQDGSCT-PCDCPHTQNTCDPETGECVCPPHTQGVKCEECEDGHWGYDAE--V 1039
Query: 788 GCPSACQCNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPC 847
GC AC C+ GS CD TG C C+ GG CD+C G+ +F C PC
Sbjct: 1040 GC-QACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGYRDF--------PDCVPC 1090
Query: 848 SCDPQGAVRDDCE---------QMTGLCSCKPGVAGPKCGQCPDG----RALGPAGC 891
CD +G D C + TG C CK V GP+C +C +G RA P GC
Sbjct: 1091 DCDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTFALRADNPLGC 1147
Score = 100 bits (249), Expect = 1e-20
Identities = 101/381 (26%), Positives = 139/381 (36%), Gaps = 72/381 (18%)
Query: 599 CETCGDAVCAFGAVCSAGQCVCPRCEHPPPGPVCGSDGV-------TYGSACELREAACL 651
CE+C + G +C CE C GV T G CE CL
Sbjct: 720 CESCLSGYYRVDGILFGG--ICQPCECHGHAAECNVHGVCIACAHNTTGVHCE----QCL 773
Query: 652 QQTQIEEARAGP--CEQAEC-----GSGGSGSGEDGDCEQELCRQ----RGGIWDEDSED 700
E +R P C+ C + S + D ++ +C G W E D
Sbjct: 774 PGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYSGAWCERCAD 833
Query: 701 GPCVCDFSCQSVPGSPV--CGSDGVTYSTECELKKARCESQRGLYVAAQGACRGPTFAPL 758
G + +VPG C G +E C+S G + G G
Sbjct: 834 GY----YGNPTVPGESCVPCDCSGNVDPSEA----GHCDSVTGECLKCLGNTDGA----- 880
Query: 759 PPVAPLHCAQTPYGCCQDNITAARGVGLAGCPSACQCNPHGSYGGTCDPATGQCSCRPGV 818
HC + G D +TA C AC+C+ GS+ C TG C C+P V
Sbjct: 881 ------HCERCADGFYGDAVTAKN------C-RACECHVKGSHSAVCHLETGLCDCKPNV 927
Query: 819 GGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDPQGAVRDDCEQMTGLCSCKPGVAGPKCG 878
G +CD+C G++ D GC PC+C G+V D C G C C PGVAG +C
Sbjct: 928 TGQQCDQCLHGYYGL-----DSGHGCRPCNCSVAGSVSDGCTD-EGQCHCVPGVAGKRCD 981
Query: 879 QCPDGRALGPAGCEADASAPATCAEMRCEFGARCVEESGSAHCVCPMLTCPEANATKVCG 938
+C A G + + P C + C E+G CVCP P K
Sbjct: 982 RC----AHGFYAYQDGSCTPCDCPHTQ----NTCDPETG--ECVCP----PHTQGVKCEE 1027
Query: 939 SDGVTYGNECQLKTIACRQGL 959
+ +G + ++ AC L
Sbjct: 1028 CEDGHWGYDAEVGCQACNCSL 1048
Score = 85.5 bits (210), Expect = 5e-16
Identities = 131/624 (20%), Positives = 231/624 (37%), Gaps = 135/624 (21%)
Query: 1420 FLALALLDGRVQLRFDTGSGPAVLTSAVPV-----EPGQWHRLELSRHWRRGTLSVDGET 1474
F ++ L+ G +++ + G G + + + GQ H + L R+ R T+ +D
Sbjct: 2544 FFSVMLIGGNIEVHVNPGDGTGLRKALLHAPTGTCSDGQAHSISLVRNRRIITVQLDENN 2603
Query: 1475 PVLGESPSGTDGLNLD-TDLFVGGVPEDQAA--VALERTFVGAGLRGCIRLLDVNNQRLE 1531
PV + + + ++ ++L+VGG+PE + + + R+F GCI+ L N + L+
Sbjct: 2604 PVEMKLGTLVESRTINVSNLYVGGIPEGEGTSLLTMRRSF-----HGCIKNLIFNLELLD 2658
Query: 1532 LGIGPGAATRGSGVGECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSP 1591
G + P ++ P D K
Sbjct: 2659 FNSAVGHEQVDLDTCWLSERP---------------------------KLAPDAEDSKLL 2691
Query: 1592 CQPNPCHGAAPCRVLPEGGAQCECPLGREGTFCQTASGQDGSGPFLADFNGFSHLELRGL 1651
+P R PE QC E G + F+ FN +
Sbjct: 2692 PEP---------RAFPE---QCVVDAALEYVPGAHQFGLTQNSHFILPFNQSA------- 2732
Query: 1652 HTFARDLGEKMALEVVFLARGPSGLLLYNGQKTDGKGDFVSLALRDRRLEFRYDLGKGAA 1711
+ +K+++E+ SGL+ Y + + D+ L L RL F +DLGKG
Sbjct: 2733 ------VRKKLSVELSIRTFASSGLIYYMAHQN--QADYAVLQLHGGRLHFMFDLGKGRT 2784
Query: 1712 VIRSREPVTLGAWTRVSLERNGRKGALRVGDGPRVLGESPV-----PHTVLNLKEPLYVG 1766
+ ++ G W V + RKG + V DG ESP+ T+L+++ Y+G
Sbjct: 2785 KVSHPALLSDGKWHTVKTDYVKRKGFITV-DG----RESPMVTVVGDGTMLDVEGLFYLG 2839
Query: 1767 GAPDFSKLARAAAVSSGFDGAIQLVSLGGRQLLTPEHVLRQVDVTSFAGHPCTRASGHPC 1826
G P + + ++ I V++ +QL + V++F
Sbjct: 2840 GLPSQYQARKIGNITHSIPACIGDVTVNSKQL------DKDSPVSAFT------------ 2881
Query: 1827 LNGASCVPREAAYVCLCPGGFSGPHCEKGLVEKSAGDVDTLAFDGRTFVEYLNAVTESEK 1886
+N V +E Y FDG Y V E K
Sbjct: 2882 VNRCYAVAQEGTY-----------------------------FDGS---GYAALVKEGYK 2909
Query: 1887 ALQSNHFELSLRTEATQGLVLWSGKATERADYVALAIVDGHLQLSYNLGSQPVVL----R 1942
+ L RT + G++L G +T + D + L +VDG + N G+ + +
Sbjct: 2910 VQSDVNITLEFRTSSQNGVLL--GISTAKVDAIGLELVDGKVLFHVNNGAGRITAAYEPK 2967
Query: 1943 STVPVNTNRWLRVVAHREQREGSLQVGNEAPVTGSSPLGATQLDTDGALWLGGLPELPVG 2002
+ + +W + A++ + +L V A S +T +DT+ +++GG P
Sbjct: 2968 TATVLCDGKWHTLQANKSKHRITLIVDGNAVGAESPHTQSTSVDTNNPIYVGGYPAGVKQ 3027
Query: 2003 PALPKAYGTGFVGCLRDVVVGRHP 2026
L T F GCLR + + + P
Sbjct: 3028 KCLRSQ--TSFRGCLRKLALIKSP 3049
Score = 75.5 bits (184), Expect = 5e-13
Identities = 48/164 (29%), Positives = 79/164 (48%), Gaps = 11/164 (6%)
Query: 1377 FEGRSFLAFPTLRAYHTLRLALEFRALEPQGLLLYNGNARGKDFLALALLDGRVQLRFDT 1436
F+G + ++ + F P GLLLY G+ KDFL++ L GRV++ D
Sbjct: 2310 FDGSGYSVVEKSLPATVTQIIMLFNTFSPNGLLLYLGSYGTKDFLSIELFRGRVKVMTDL 2369
Query: 1437 GSGPAVLTSAVPVEPGQWHRLELSRHWRRGTLSV------DGETPVLGESPSGTDGLN-L 1489
GSGP L + G W+++ R+ ++G L+V + GE+P + LN L
Sbjct: 2370 GSGPITLLTDRRYNNGTWYKIAFQRNRKQGVLAVIDAYNTSNKETKQGETPGASSDLNRL 2429
Query: 1490 DTD-LFVGGVPEDQAAVALERTFVGAGLRGCIRLLDVNNQRLEL 1532
D D ++VGG+P + + R GCI+ L+++ +L
Sbjct: 2430 DKDPIYVGGLPRSR---VVRRGVTTKSFVGCIKNLEISRSTFDL 2470
Score = 73.6 bits (179), Expect = 2e-12
Identities = 94/386 (24%), Positives = 157/386 (40%), Gaps = 87/386 (22%)
Query: 1673 PSGLLLYNGQKTDGKGDFVSLALRDRRLEFRYDLGKGAAVIRSRE-PVTLGAWTRVSLER 1731
P LL Y G T DF+++ +R R+ F +DLG G+ + + P+ W + + R
Sbjct: 2151 PDNLLFYLGSST--ASDFLAVEMRRGRVAFLWDLGSGSTRLEFPDFPIDDNRWHSIHVAR 2208
Query: 1732 NGRKGALRVGD------GPRVLGESPVPHTVLNLKEP--LYVGGAPDFSKLARAAAVSSG 1783
G G+L V + P +SP VL++ ++VGG
Sbjct: 2209 FGNIGSLSVKEMSSNQKSPTKTSKSPGTANVLDVNNSTLMFVGG---------------- 2252
Query: 1784 FDGAIQLVSLGGRQLLTPEHVLRQVDVTSFAGHPCTRASGHPCLNGASC-----VPREAA 1838
LGG+ +P V VT F G G LNG S + RE
Sbjct: 2253 ---------LGGQIKKSPA-----VKVTHFKG-----CLGEAFLNGKSIGLWNYIEREGK 2293
Query: 1839 YVCLCPGGFSGPHCEKGLVEKSAGDVDTLAFDGRTFVEYLNAVTESEKALQSNHFELSLR 1898
C G F S + + FDG + +V E +
Sbjct: 2294 ----CRGCFGS----------SQNEDPSFHFDGSGY-----SVVEKSLPATVTQIIMLFN 2334
Query: 1899 TEATQGLVLWSGKATERADYVALAIVDGHLQLSYNLGSQPVVLRSTVPVNTNRWLRVVAH 1958
T + GL+L+ G + D++++ + G +++ +LGS P+ L + N W ++
Sbjct: 2335 TFSPNGLLLYLGSYGTK-DFLSIELFRGRVKVMTDLGSGPITLLTDRRYNNGTWYKIAFQ 2393
Query: 1959 REQREGSLQV------GNEAPVTGSSPLGAT----QLDTDGALWLGGLPELPVGPALPKA 2008
R +++G L V N+ G +P GA+ +LD D +++GGLP V + +
Sbjct: 2394 RNRKQGVLAVIDAYNTSNKETKQGETP-GASSDLNRLDKD-PIYVGGLPRSRV---VRRG 2448
Query: 2009 YGT-GFVGCLRDVVVGRHPLHLLEDA 2033
T FVGC++++ + R LL ++
Sbjct: 2449 VTTKSFVGCIKNLEISRSTFDLLRNS 2474
Score = 67.8 bits (164), Expect = 1e-10
Identities = 37/114 (32%), Positives = 48/114 (42%), Gaps = 25/114 (21%)
Query: 793 CQCNPHGSYGGTC-----------DPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGR 841
C C+P GS C GQC C+ G G +CDRC+ G+ ++
Sbjct: 397 CNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYKDY-------- 448
Query: 842 SGCTPCSCDPQGAVRDDCEQMTGLCSCKPGVAGPKCGQCPDG----RALGPAGC 891
C C C+P G+ D E TG C CK V G C +C G + P GC
Sbjct: 449 PTCVSCGCNPVGSASD--EPCTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGC 500
Score = 67.4 bits (163), Expect = 1e-10
Identities = 36/95 (37%), Positives = 46/95 (48%), Gaps = 23/95 (24%)
Query: 768 QTPYGCCQDNITAARGVGLAGCPSACQCNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCE 827
QTP G CQ C CNPHGS G CD +GQC CR G GLRCD CE
Sbjct: 1500 QTPGGSCQK----------------CDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDECE 1543
Query: 828 PGFWNFRGIVTDGRSGCTPCSCDPQGAVRDDCEQM 862
P R I+ + + C C + G + +D +++
Sbjct: 1544 P-----RHILME--TDCVSCDDECVGVLLNDLDEI 1571
Score = 63.2 bits (152), Expect = 3e-09
Identities = 112/450 (24%), Positives = 149/450 (33%), Gaps = 103/450 (22%)
Query: 465 PSPCLG--VQCAFGATC-AVKNGQAACECLQACSSLY-DPVCGSDGVTYGSACELEATA- 519
P C G +C C A + C Q Y +P G+ G AC L +
Sbjct: 741 PCECHGHAAECNVHGVCIACAHNTTGVHCEQCLPGFYGEPSRGTPGDCQPCACPLTIASN 800
Query: 520 -----CTLGREIQVARKGPCDRCGQCRFGALCE----AETGRCVCPSE-CVALAQPVCGS 569
C L +V CD C GA CE G P E CV C
Sbjct: 801 NFSPTCHLNDGDEVV----CDWCAPGYSGAWCERCADGYYGNPTVPGESCVP-----CDC 851
Query: 570 DGHTYPSECMLHVHACTHQI--SLHVASAGPCETCGDAVCAFGAVCSAGQCVCPRCEHPP 627
G+ PSE H + T + L CE C D +G +A C C
Sbjct: 852 SGNVDPSEAG-HCDSVTGECLKCLGNTDGAHCERCADGF--YGDAVTAKNCRACECH--- 905
Query: 628 PGPVCGSDGVTYGSACELREAAC-----LQQTQIEEARAG-----------PCEQAECGS 671
V GS + + C L C + Q ++ G PC + GS
Sbjct: 906 ---VKGS----HSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLDSGHGCRPCNCSVAGS 958
Query: 672 GGSGSGEDGDCE-------QELCRQRGGIWD-EDSEDGPCVCDFS---CQSVPGSPVCGS 720
G ++G C + R G + +D PC C + C G VC
Sbjct: 959 VSDGCTDEGQCHCVPGVAGKRCDRCAHGFYAYQDGSCTPCDCPHTQNTCDPETGECVCPP 1018
Query: 721 DGVTYSTECELKKARCESQRGLYVAAQG--ACR----GPTFAPLPPVAPLHC-AQTPYG- 772
T +CE CE Y A G AC G T V HC ++ +G
Sbjct: 1019 H--TQGVKCE----ECEDGHWGYDAEVGCQACNCSLVGSTHHRCDVVTG-HCQCKSKFGG 1071
Query: 773 --CCQDNITAARGVGLAGCPSA--CQCNPHGSYGGTCD---------PATGQCSCRPGVG 819
C Q ++ G P C C+ G+ G C+ TG C C+ V
Sbjct: 1072 RACDQCSL------GYRDFPDCVPCDCDLRGTSGDACNLEQGLCGCVEETGACPCKENVF 1125
Query: 820 GLRCDRCEPGFWNFRGIVTDGRSGCTPCSC 849
G +C+ C G + R D GC+PC C
Sbjct: 1126 GPQCNECREGTFALR---ADNPLGCSPCFC 1152
Score = 62.0 bits (149), Expect = 6e-09
Identities = 43/132 (32%), Positives = 66/132 (50%), Gaps = 11/132 (8%)
Query: 1666 VVFLARGPSGLLLYNGQKTDGKGDFVSLALRDRRLEFRYDLGKGAAVIRSREPVTLGAWT 1725
++F P+GLLLY G G DF+S+ L R++ DLG G + + G W
Sbjct: 2331 MLFNTFSPNGLLLYLGSY--GTKDFLSIELFRGRVKVMTDLGSGPITLLTDRRYNNGTWY 2388
Query: 1726 RVSLERNGRKGALRVGDGPRV------LGESPVPHTVLNL--KEPLYVGGAPDFSKLARA 1777
+++ +RN ++G L V D GE+P + LN K+P+YVGG P S++ R
Sbjct: 2389 KIAFQRNRKQGVLAVIDAYNTSNKETKQGETPGASSDLNRLDKDPIYVGGLPR-SRVVRR 2447
Query: 1778 AAVSSGFDGAIQ 1789
+ F G I+
Sbjct: 2448 GVTTKSFVGCIK 2459
Score = 61.6 bits (148), Expect = 8e-09
Identities = 33/104 (31%), Positives = 48/104 (46%), Gaps = 7/104 (6%)
Query: 792 ACQCNPHGSYGGTC----DPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPC 847
AC +P S+ TC D +C G G C+RC ++ T G S C C
Sbjct: 1453 ACPHSPPASFSPTCVLEGDHDFRCDACLLGYEGKHCERCSSSYYG--NPQTPGGS-CQKC 1509
Query: 848 SCDPQGAVRDDCEQMTGLCSCKPGVAGPKCGQCPDGRALGPAGC 891
C+P G+V DC++ +G C C+ G +G +C +C L C
Sbjct: 1510 DCNPHGSVHGDCDRTSGQCVCRLGASGLRCDECEPRHILMETDC 1553
Score = 58.5 bits (140), Expect = 6e-08
Identities = 36/107 (33%), Positives = 52/107 (48%), Gaps = 15/107 (14%)
Query: 764 LHCAQTPYGC-CQDNITAAR----GVGLAGCPS--ACQCNPHGSYGGTCDPATGQCSCRP 816
LH + P C C++ T + +G P+ +C CNP GS + +P TG C C+
Sbjct: 418 LHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYPTCVSCGCNPVGS--ASDEPCTGPCVCKE 475
Query: 817 GVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDPQGAVRDDCEQMT 863
V G CDRC+PGF+N + GC+ C C V D C ++
Sbjct: 476 NVEGKACDRCKPGFYNLK---EKNPRGCSECFC---FGVSDVCSSLS 516
Score = 57.8 bits (138), Expect = 1e-07
Identities = 40/143 (27%), Positives = 66/143 (46%), Gaps = 12/143 (8%)
Query: 1394 LRLALEFRALEPQGLLLYNGNARGKDFLALALLDGRVQLRFDTGSGPAVLTSAVPVEPGQ 1453
L + L R GL+ Y + D+ L L GR+ FD G G ++ + G+
Sbjct: 2737 LSVELSIRTFASSGLIYYMAHQNQADYAVLQLHGGRLHFMFDLGKGRTKVSHPALLSDGK 2796
Query: 1454 WHRLELSRHWRRGTLSVDGETPVLGESPSGT---DGLNLDTD--LFVGGVPEDQAAVALE 1508
WH ++ R+G ++VDG ESP T DG LD + ++GG+P A +
Sbjct: 2797 WHTVKTDYVKRKGFITVDGR-----ESPMVTVVGDGTMLDVEGLFYLGGLPSQYQARKIG 2851
Query: 1509 RTFVGAGLRGCIRLLDVNNQRLE 1531
+ + CI + VN+++L+
Sbjct: 2852 N--ITHSIPACIGDVTVNSKQLD 2872
Score = 57.4 bits (137), Expect = 1e-07
Identities = 38/122 (31%), Positives = 60/122 (49%), Gaps = 9/122 (7%)
Query: 1386 PTLRAYHTLRLALEFRALEPQGLLLYNGNARGKDFLALALLDGRVQLRFDTGSGPAVLT- 1444
P + + + L L + EP LL Y G++ DFLA+ + GRV +D GSG L
Sbjct: 2132 PQISSTNYNTLTLNVKTQEPDNLLFYLGSSTASDFLAVEMRRGRVAFLWDLGSGSTRLEF 2191
Query: 1445 SAVPVEPGQWHRLELSRHWRRGTLSV-----DGETPVLGESPSGTDG---LNLDTDLFVG 1496
P++ +WH + ++R G+LSV + ++P GT +N T +FVG
Sbjct: 2192 PDFPIDDNRWHSIHVARFGNIGSLSVKEMSSNQKSPTKTSKSPGTANVLDVNNSTLMFVG 2251
Query: 1497 GV 1498
G+
Sbjct: 2252 GL 2253
Score = 55.1 bits (131), Expect = 7e-07
Identities = 48/155 (30%), Positives = 73/155 (47%), Gaps = 14/155 (9%)
Query: 1377 FEGRSFLAFPT--LRAYHTLRLALEFRALEPQGLLLYNGNARGKDFLALALLDGRVQLRF 1434
F+G + A + + + LEFR G+LL A+ D + L L+DG+V
Sbjct: 2895 FDGSGYAALVKEGYKVQSDVNITLEFRTSSQNGVLLGISTAK-VDAIGLELVDGKVLFHV 2953
Query: 1435 DTGSGPAVLT----SAVPVEPGQWHRLELSRHWRRGTLSVDGETPVLGESPSGTDGLNLD 1490
+ G+G +A + G+WH L+ ++ R TL VDG V ESP T ++D
Sbjct: 2954 NNGAGRITAAYEPKTATVLCDGKWHTLQANKSKHRITLIVDGNA-VGAESPH-TQSTSVD 3011
Query: 1491 TD--LFVGGVPEDQAAVALERTFVGAGLRGCIRLL 1523
T+ ++VGG P A V + RGC+R L
Sbjct: 3012 TNNPIYVGGYP---AGVKQKCLRSQTSFRGCLRKL 3043
Score = 54.7 bits (130), Expect = 9e-07
Identities = 56/247 (22%), Positives = 78/247 (31%), Gaps = 59/247 (23%)
Query: 698 SEDGPCVCDFSCQSVPGSPVCGSDGVTYSTECELKKARCESQRGLYVAAQGACRGPTFAP 757
S G C+C S P D T +C+ + C + C G P
Sbjct: 265 SVGGMCICYGHASSCPW------DETTKKLQCQCEHNTCGE------SCNRCCPGYHQQP 312
Query: 758 LPP--------VAPLHCAQTPYGCCQDNITAARGVGLAGCPSACQCNPHGSY--GGTCDP 807
P +C C D A + L N G + GG C
Sbjct: 313 WRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKSL---------NTAGQFRGGGVC-- 361
Query: 808 ATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDPQGA-----VRDDCE-- 860
+C G+ C+ C G++ + C PC+CDP G+ ++DD
Sbjct: 362 ----INCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSD 417
Query: 861 ----QMTGLCSCKPGVAGPKCGQCPDGRALGPAGCEADASAPATCAEMRCEFGARCVEES 916
+ G C CK G G KC +C G P TC C +E
Sbjct: 418 LHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYP-----------TCVSCGCNPVGSASDEP 466
Query: 917 GSAHCVC 923
+ CVC
Sbjct: 467 CTGPCVC 473
Score = 53.1 bits (126), Expect = 3e-06
Identities = 48/172 (27%), Positives = 64/172 (37%), Gaps = 30/172 (17%)
Query: 793 CQCNPHGSYGGTCDPATGQC-SCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSC-- 849
C CN H TCDP TG+C +C G CD C G++ G VT S C C+C
Sbjct: 1403 CSCNNHSD---TCDPNTGKCLNCGDNTAGDHCDVCTSGYY---GKVTGSASDCALCACPH 1456
Query: 850 DPQGAVRDDC----EQMTGLCSCKPGVAGPKCGQCPD---GRALGPAG-CEADASAPATC 901
P + C + +C G G C +C G P G C+ P
Sbjct: 1457 SPPASFSPTCVLEGDHDFRCDACLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGS 1516
Query: 902 AEMRCEFGARCVEESGSAHCVCPM----LTCPEANATKV-CGSDGVTYGNEC 948
C + S CVC + L C E + +D V+ +EC
Sbjct: 1517 VHGDC--------DRTSGQCVCRLGASGLRCDECEPRHILMETDCVSCDDEC 1560
Score = 52.0 bits (123), Expect = 6e-06
Identities = 35/113 (30%), Positives = 43/113 (38%), Gaps = 14/113 (12%)
Query: 812 CSCRPGVGGLRCDRCEPGFWNFRGIVTDGR--------SGCTPCSCDPQGAVRDDCEQMT 863
C C PG G C C PG+ RG + G + C PCSC+ D C+ T
Sbjct: 1362 CVCPPGTVGFSCQDCAPGY--HRGKLPAGSDRGPRPLVAPCVPCSCNNHS---DTCDPNT 1416
Query: 864 GLC-SCKPGVAGPKCGQCPDGRALGPAGCEADASAPATCAEMRCEFGARCVEE 915
G C +C AG C C G G +D + A F CV E
Sbjct: 1417 GKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLE 1469
Score = 43.9 bits (102), Expect = 0.002
Identities = 51/209 (24%), Positives = 69/209 (33%), Gaps = 42/209 (20%)
Query: 553 CVCPSECVALAQPVC-----------GSDGHTYPSECMLHVHACTHQISLHVASAGPCET 601
CVCP V + C GSD P +C + + G C
Sbjct: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGKCLN 1421
Query: 602 CGDA-------VCAFG----AVCSAGQCVCPRCEHPPP---GPVCGSDGVTYGSACELRE 647
CGD VC G SA C C H PP P C +G + C+
Sbjct: 1422 CGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEG-DHDFRCD--- 1477
Query: 648 AACLQQTQIEEARAGPCEQAECGSGGSGSGEDGDCEQELCRQRGGI-WDEDSEDGPCVCD 706
ACL + + CE+ G+ G C++ C G + D D G CVC
Sbjct: 1478 -ACLLGYEGKH-----CERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVCR 1531
Query: 707 FSCQSV------PGSPVCGSDGVTYSTEC 729
+ P + +D V+ EC
Sbjct: 1532 LGASGLRCDECEPRHILMETDCVSCDDEC 1560
Score = 34.7 bits (78), Expect = 0.98
Identities = 81/306 (26%), Positives = 97/306 (31%), Gaps = 67/306 (21%)
Query: 256 GSTCARSADGLTASCLCPATCRGAPEGTVCGSDGADYPGECQLLRRACARQENVFKKFDG 315
G+ C R ADG + CR A E V GS A C L C + NV +
Sbjct: 879 GAHCERCADGFYGDAVTAKNCR-ACECHVKGSHSA----VCHLETGLCDCKPNVTGQ--- 930
Query: 316 PCDPCQGAL--PDPSRSCRVNPRTRRPEMLLRPESC--PARQAPVCGDDGVTYENDCVMG 371
CD C D C RP +C + C D+G + CV G
Sbjct: 931 QCDQCLHGYYGLDSGHGC-------------RPCNCSVAGSVSDGCTDEGQCH---CVPG 974
Query: 372 RSG-----AARGLLLQKVRSGQCQGRDQCPEPCRFNAVCLSRRGRPRCSCDRVTCDGAYR 426
+G A G + G C D CP C G C C T G
Sbjct: 975 VAGKRCDRCAHG--FYAYQDGSCTPCD-CPHT---QNTCDPETG--ECVCPPHT-QGVKC 1025
Query: 427 PVCAQDGRTYDSDCWRQQAECRQQRAIPSKHQGPCDQAPSPCLGVQCAFGATCAVKNGQA 486
C YD++ Q C + S H CD C C K G
Sbjct: 1026 EECEDGHWGYDAEVGCQACNC---SLVGSTHH-RCDVVTGHC---------QCKSKFGGR 1072
Query: 487 AC-ECLQACSSLYDPV-CGSD-GVTYGSACELEATACTLGREIQVARKGPC------DRC 537
AC +C D V C D T G AC LE C E PC +C
Sbjct: 1073 ACDQCSLGYRDFPDCVPCDCDLRGTSGDACNLEQGLCGCVEETGAC---PCKENVFGPQC 1129
Query: 538 GQCRFG 543
+CR G
Sbjct: 1130 NECREG 1135
Score = 34.3 bits (77), Expect = 1.3
Identities = 22/66 (33%), Positives = 25/66 (37%), Gaps = 16/66 (24%)
Query: 1573 HCQCPPGRVGPTCADEKSP------------CQPNPCHG-AAPCRVLPEGGAQCECPLGR 1619
HC+CP G G +C S CQP CHG AA C V G C
Sbjct: 708 HCECPQGYTGTSCESCLSGYYRVDGILFGGICQPCECHGHAAECNV---HGVCIACAHNT 764
Query: 1620 EGTFCQ 1625
G C+
Sbjct: 765 TGVHCE 770
>gi|110611156 laminin, gamma 3 precursor [Homo sapiens]
Length = 1575
Score = 107 bits (267), Expect = 1e-22
Identities = 112/427 (26%), Positives = 148/427 (34%), Gaps = 72/427 (16%)
Query: 501 VCGSDGVTYGSACELEATACTLGREIQVARKGPCDRCGQCRFG--ALCEAETGRCVCPSE 558
+C G CE +C G + ++ + GP C C C+ TG CVC
Sbjct: 672 ICSCPTGYTGQFCE----SCAPGYKREMPQGGPYASCVPCTCNQHGTCDPNTGICVCSHH 727
Query: 559 CVALAQPVC--GSDGHTYPSECMLHVHACTHQISLHVASAGPCETCGDAVCAFGAVCSAG 616
+ C G G+ + + PC G + C + +
Sbjct: 728 TEGPSCERCLPGFYGNPFAGQA---------------DDCQPCPCPGQSACT--TIPESR 770
Query: 617 QCVCPRCEHPPPGPVCGSDGVTYGSACELREAACLQQTQIEEARAGPCEQAECGSGGSGS 676
+ VC C PPG G CE+ + PC Q +C SG
Sbjct: 771 EVVCTHC---PPGQ--------RGRRCEVCDDGFFGDPLGLFGHPQPCHQCQC-SGNVDP 818
Query: 677 GEDGDCEQELCRQRGGIWDEDSEDGPCVCDFSCQSVPGSPVC--GSDGVTYSTECELKKA 734
G+C D G C+ + C G G + K
Sbjct: 819 NAVGNC--------------DPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCM 864
Query: 735 RCESQRGLYVAAQGACRGPT--FAPLPPVAPLHCAQTPYGCCQDNITAARGVGLAGCPSA 792
C V+ Q C T + LP V C++ C G GC S
Sbjct: 865 PCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSR----CYPGFFDLQPG---RGCRS- 916
Query: 793 CQCNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDPQ 852
C+C+P GS C P TGQC+CRPGV G CDRC+ GF+ F GC C C P
Sbjct: 917 CKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGF------SIKGCRACRCSPL 970
Query: 853 GAVRDDCEQMTGLCSCKPGVAGPKCGQCPDGRALGPAG--CEADASAPATCAEMRCEFGA 910
GA C + G C C+PG G KC +C D L G C+ S A E + A
Sbjct: 971 GAASAQCHE-NGTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQCPSCYALVKEEAAKLKA 1029
Query: 911 RCVEESG 917
R G
Sbjct: 1030 RLTLTEG 1036
Score = 73.9 bits (180), Expect = 1e-12
Identities = 68/231 (29%), Positives = 86/231 (37%), Gaps = 53/231 (22%)
Query: 793 CQCNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWN--FRGIVTDGRSGCTPCSCD 850
C CN HG TCDP TG C C G C+RC PGF+ F G D C PC C
Sbjct: 707 CTCNQHG----TCDPNTGICVCSHHTEGPSCERCLPGFYGNPFAGQADD----CQPCPCP 758
Query: 851 PQGAVRDDCEQMTGLCS-CKPGVAGPKCGQCPDGRALGPAGCEADASAPATCAEMRCEFG 909
Q A E +C+ C PG G +C C DG P G P C + +C
Sbjct: 759 GQSACTTIPESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGL---FGHPQPCHQCQCSGN 815
Query: 910 ------ARCVEESGSAHCVCPMLTCPEANATKVCGSDGVTYGNECQLKTIACRQGLQISI 963
C SG HC L C T G+ C+ C++G S
Sbjct: 816 VDPNAVGNCDPLSG--HC----LRCLHN-----------TTGDHCE----HCQEGFYGSA 854
Query: 964 QSLGPCQEAVAPSTHPTSASVTVTTPGLLLSQALPAPP--GALPLAPSSTA 1012
+ P + + S HP + +S+ +P P G P TA
Sbjct: 855 LAPRPADKCMPCSCHPQGS----------VSEQMPCDPVTGQCSCLPHVTA 895
Score = 65.5 bits (158), Expect = 5e-10
Identities = 67/240 (27%), Positives = 88/240 (36%), Gaps = 47/240 (19%)
Query: 615 AGQCVCPRCEHPPPGPVCGSDGVTYGSACELREAACLQQTQIEEARAGPCEQA-EC-GSG 672
AGQ C RC+H T G+ CE CL Q G E A EC
Sbjct: 285 AGQLAC-RCQHN-----------TTGTDCE----RCLPFFQDRPWARGTAEAAHECLPCN 328
Query: 673 GSGSGEDGDCEQELCRQRGGIWDEDSEDGPCVCDFSCQSVPGSPVCGSDGVTYSTECELK 732
SG E+ ++EL R G G C + P C + + +
Sbjct: 329 CSGRSEECTFDRELFRSTG-------HGGRCHHCRDHTAGPHCERCQENFYHWDPRMPCQ 381
Query: 733 KARCESQRGLYVAAQ--GACRGPTFAPLPPVAPLHCAQTPYGC-CQDNITAARGVGLAGC 789
C+S L++ G C C T G C + + GC
Sbjct: 382 PCDCQSAGSLHLQCDDTGTCA--------------CKPTVTGWKCDRCLPGFHSLSEGGC 427
Query: 790 PSACQCNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSC 849
C CNP GS TCDP +G+C C+ V G CDRC PG +N + +GC+ C C
Sbjct: 428 -RPCTCNPAGSLD-TCDPRSGRCPCKENVEGNLCDRCRPGTFNLQ---PHNPAGCSSCFC 482
Score = 62.4 bits (150), Expect = 4e-09
Identities = 48/182 (26%), Positives = 67/182 (36%), Gaps = 16/182 (8%)
Query: 759 PPVAPLHCAQTPYGCCQDNITAARGVGLAGCPSACQCNPHGSYGGTCDPATGQ--CSCRP 816
PP+ P H + + + G AG + + G PA+ CSC
Sbjct: 618 PPLPPFHFQRLLANLTSLRLRVSPGPSPAGPVFLTEVRLTSARPGLSPPASWVEICSCPT 677
Query: 817 GVGGLRCDRCEPGFWNFRGIVTDG-RSGCTPCSCDPQGAVRDDCEQMTGLCSCKPGVAGP 875
G G C+ C PG+ R + G + C PC+C+ G C+ TG+C C GP
Sbjct: 678 GYTGQFCESCAPGY--KREMPQGGPYASCVPCTCNQHGT----CDPNTGICVCSHHTEGP 731
Query: 876 KCGQCPDGRALGPAGCEADASAPATCAEMRCEFGARCVEESGSAHCVCPMLTCPEANATK 935
C +C G P +AD P C + C S VC CP +
Sbjct: 732 SCERCLPGFYGNPFAGQADDCQPCPCPGQ-----SACTTIPESREVVC--THCPPGQRGR 784
Query: 936 VC 937
C
Sbjct: 785 RC 786
Score = 50.4 bits (119), Expect = 2e-05
Identities = 30/85 (35%), Positives = 37/85 (43%), Gaps = 15/85 (17%)
Query: 793 CQCNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRG--------------IVT 838
C C GS CD TG C+C+P V G +CDRC PGF +
Sbjct: 383 CDCQSAGSLHLQCDD-TGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLDTC 441
Query: 839 DGRSGCTPCSCDPQGAVRDDCEQMT 863
D RSG PC + +G + D C T
Sbjct: 442 DPRSGRCPCKENVEGNLCDRCRPGT 466
Score = 47.0 bits (110), Expect = 2e-04
Identities = 49/205 (23%), Positives = 69/205 (33%), Gaps = 49/205 (23%)
Query: 793 CQCNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWN---FRGIVTDGRSGCTPCSC 849
C+CN H S G C C+ G C+RC P F + RG + C PC+C
Sbjct: 271 CKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARG-TAEAAHECLPCNC 329
Query: 850 DPQGAVRDDCE------QMTG----LCSCKPGVAGPKCGQCPDG-------RALGPAGCE 892
+ ++C + TG C+ AGP C +C + P C+
Sbjct: 330 SGRS---EECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMPCQPCDCQ 386
Query: 893 ADASAPATCAEM---------------RCEFGARCVEESGSAHCVC----PMLTCPEANA 933
+ S C + RC G + E G C C + TC +
Sbjct: 387 SAGSLHLQCDDTGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLDTCDPRSG 446
Query: 934 TKVCGSDGVTYGNECQLKTIACRQG 958
C + GN C CR G
Sbjct: 447 RCPCKEN--VEGNLCD----RCRPG 465
Score = 43.5 bits (101), Expect = 0.002
Identities = 27/81 (33%), Positives = 34/81 (41%), Gaps = 5/81 (6%)
Query: 1548 CGDH-PCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVL 1606
C H C PN G C + G +C PG G A + CQP PC G + C +
Sbjct: 709 CNQHGTCDPNT--GICVCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTI 766
Query: 1607 PEGG--AQCECPLGREGTFCQ 1625
PE CP G+ G C+
Sbjct: 767 PESREVVCTHCPPGQRGRRCE 787
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.443
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 101,291,691
Number of Sequences: 37866
Number of extensions: 6021731
Number of successful extensions: 44192
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 287
Number of HSP's successfully gapped in prelim test: 939
Number of HSP's that attempted gapping in prelim test: 25703
Number of HSP's gapped (non-prelim): 14284
length of query: 2045
length of database: 18,247,518
effective HSP length: 118
effective length of query: 1927
effective length of database: 13,779,330
effective search space: 26552768910
effective search space used: 26552768910
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.