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Search of human proteins with 54792098
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|54792098 erbB-2 isoform b [Homo sapiens]
(1225 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|54792098 erbB-2 isoform b [Homo sapiens] 2568 0.0
gi|54792096 erbB-2 isoform a [Homo sapiens] 2568 0.0
gi|29725609 epidermal growth factor receptor isoform a precursor... 1186 0.0
gi|110825958 v-erb-a erythroblastic leukemia viral oncogene homo... 1129 0.0
gi|4885215 v-erb-a erythroblastic leukemia viral oncogene homolo... 1120 0.0
gi|54792100 erbB-3 isoform 1 precursor [Homo sapiens] 914 0.0
gi|41327736 epidermal growth factor receptor isoform d precursor... 568 e-161
gi|41327732 epidermal growth factor receptor isoform b precursor... 568 e-161
gi|41327734 epidermal growth factor receptor isoform c precursor... 351 3e-96
gi|32967311 ephrin receptor EphA2 [Homo sapiens] 215 2e-55
gi|32528301 EPH receptor B4 precursor [Homo sapiens] 214 4e-55
gi|4758284 ephrin receptor EphB1 precursor [Homo sapiens] 211 3e-54
gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo sap... 206 8e-53
gi|27886593 PTK2 protein tyrosine kinase 2 isoform b [Homo sapiens] 206 8e-53
gi|24476013 PTK2 protein tyrosine kinase 2 isoform a [Homo sapiens] 206 8e-53
gi|27886590 PTK2B protein tyrosine kinase 2 beta isoform a [Homo... 204 3e-52
gi|27886588 PTK2B protein tyrosine kinase 2 beta isoform b [Homo... 204 3e-52
gi|27886586 PTK2B protein tyrosine kinase 2 beta isoform a [Homo... 204 3e-52
gi|27886584 PTK2B protein tyrosine kinase 2 beta isoform a [Homo... 204 3e-52
gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo sap... 204 4e-52
gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo sapi... 202 1e-51
gi|4758280 ephrin receptor EphA4 [Homo sapiens] 202 1e-51
gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens] 202 1e-51
gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo sap... 202 2e-51
gi|56549666 tyrosine kinase, non-receptor, 2 isoform 1 [Homo sap... 201 4e-51
gi|58331191 tyrosine kinase, non-receptor, 2 isoform 2 [Homo sap... 201 4e-51
gi|153266778 arg tyrosine kinase isoform c [Homo sapiens] 201 5e-51
gi|6382062 arg tyrosine kinase isoform b [Homo sapiens] 201 5e-51
gi|209862772 arg tyrosine kinase isoform d [Homo sapiens] 201 5e-51
gi|153266757 arg tyrosine kinase isoform a [Homo sapiens] 201 5e-51
>gi|54792098 erbB-2 isoform b [Homo sapiens]
Length = 1225
Score = 2568 bits (6657), Expect = 0.0
Identities = 1225/1225 (100%), Positives = 1225/1225 (100%)
Query: 1 MKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQDIQEVQGYVLIAHNQ 60
MKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQDIQEVQGYVLIAHNQ
Sbjct: 1 MKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQDIQEVQGYVLIAHNQ 60
Query: 61 VRQVPLQRLRIVRGTQLFEDNYALAVLDNGDPLNNTTPVTGASPGGLRELQLRSLTEILK 120
VRQVPLQRLRIVRGTQLFEDNYALAVLDNGDPLNNTTPVTGASPGGLRELQLRSLTEILK
Sbjct: 61 VRQVPLQRLRIVRGTQLFEDNYALAVLDNGDPLNNTTPVTGASPGGLRELQLRSLTEILK 120
Query: 121 GGVLIQRNPQLCYQDTILWKDIFHKNNQLALTLIDTNRSRACHPCSPMCKGSRCWGESSE 180
GGVLIQRNPQLCYQDTILWKDIFHKNNQLALTLIDTNRSRACHPCSPMCKGSRCWGESSE
Sbjct: 121 GGVLIQRNPQLCYQDTILWKDIFHKNNQLALTLIDTNRSRACHPCSPMCKGSRCWGESSE 180
Query: 181 DCQSLTRTVCAGGCARCKGPLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPA 240
DCQSLTRTVCAGGCARCKGPLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPA
Sbjct: 181 DCQSLTRTVCAGGCARCKGPLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPA 240
Query: 241 LVTYNTDTFESMPNPEGRYTFGASCVTACPYNYLSTDVGSCTLVCPLHNQEVTAEDGTQR 300
LVTYNTDTFESMPNPEGRYTFGASCVTACPYNYLSTDVGSCTLVCPLHNQEVTAEDGTQR
Sbjct: 241 LVTYNTDTFESMPNPEGRYTFGASCVTACPYNYLSTDVGSCTLVCPLHNQEVTAEDGTQR 300
Query: 301 CEKCSKPCARVCYGLGMEHLREVRAVTSANIQEFAGCKKIFGSLAFLPESFDGDPASNTA 360
CEKCSKPCARVCYGLGMEHLREVRAVTSANIQEFAGCKKIFGSLAFLPESFDGDPASNTA
Sbjct: 301 CEKCSKPCARVCYGLGMEHLREVRAVTSANIQEFAGCKKIFGSLAFLPESFDGDPASNTA 360
Query: 361 PLQPEQLQVFETLEEITGYLYISAWPDSLPDLSVFQNLQVIRGRILHNGAYSLTLQGLGI 420
PLQPEQLQVFETLEEITGYLYISAWPDSLPDLSVFQNLQVIRGRILHNGAYSLTLQGLGI
Sbjct: 361 PLQPEQLQVFETLEEITGYLYISAWPDSLPDLSVFQNLQVIRGRILHNGAYSLTLQGLGI 420
Query: 421 SWLGLRSLRELGSGLALIHHNTHLCFVHTVPWDQLFRNPHQALLHTANRPEDECVGEGLA 480
SWLGLRSLRELGSGLALIHHNTHLCFVHTVPWDQLFRNPHQALLHTANRPEDECVGEGLA
Sbjct: 421 SWLGLRSLRELGSGLALIHHNTHLCFVHTVPWDQLFRNPHQALLHTANRPEDECVGEGLA 480
Query: 481 CHQLCARGHCWGPGPTQCVNCSQFLRGQECVEECRVLQGLPREYVNARHCLPCHPECQPQ 540
CHQLCARGHCWGPGPTQCVNCSQFLRGQECVEECRVLQGLPREYVNARHCLPCHPECQPQ
Sbjct: 481 CHQLCARGHCWGPGPTQCVNCSQFLRGQECVEECRVLQGLPREYVNARHCLPCHPECQPQ 540
Query: 541 NGSVTCFGPEADQCVACAHYKDPPFCVARCPSGVKPDLSYMPIWKFPDEEGACQPCPINC 600
NGSVTCFGPEADQCVACAHYKDPPFCVARCPSGVKPDLSYMPIWKFPDEEGACQPCPINC
Sbjct: 541 NGSVTCFGPEADQCVACAHYKDPPFCVARCPSGVKPDLSYMPIWKFPDEEGACQPCPINC 600
Query: 601 THSCVDLDDKGCPAEQRASPLTSIISAVVGILLVVVLGVVFGILIKRRQQKIRKYTMRRL 660
THSCVDLDDKGCPAEQRASPLTSIISAVVGILLVVVLGVVFGILIKRRQQKIRKYTMRRL
Sbjct: 601 THSCVDLDDKGCPAEQRASPLTSIISAVVGILLVVVLGVVFGILIKRRQQKIRKYTMRRL 660
Query: 661 LQETELVEPLTPSGAMPNQAQMRILKETELRKVKVLGSGAFGTVYKGIWIPDGENVKIPV 720
LQETELVEPLTPSGAMPNQAQMRILKETELRKVKVLGSGAFGTVYKGIWIPDGENVKIPV
Sbjct: 661 LQETELVEPLTPSGAMPNQAQMRILKETELRKVKVLGSGAFGTVYKGIWIPDGENVKIPV 720
Query: 721 AIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQLVTQLMPYGCLLDHV 780
AIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQLVTQLMPYGCLLDHV
Sbjct: 721 AIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQLVTQLMPYGCLLDHV 780
Query: 781 RENRGRLGSQDLLNWCMQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLL 840
RENRGRLGSQDLLNWCMQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLL
Sbjct: 781 RENRGRLGSQDLLNWCMQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLL 840
Query: 841 DIDETEYHADGGKVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPARE 900
DIDETEYHADGGKVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPARE
Sbjct: 841 DIDETEYHADGGKVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPARE 900
Query: 901 IPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSEFSRMARDPQRFVVIQ 960
IPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSEFSRMARDPQRFVVIQ
Sbjct: 901 IPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSEFSRMARDPQRFVVIQ 960
Query: 961 NEDLGPASPLDSTFYRSLLEDDDMGDLVDAEEYLVPQQGFFCPDPAPGAGGMVHHRHRSS 1020
NEDLGPASPLDSTFYRSLLEDDDMGDLVDAEEYLVPQQGFFCPDPAPGAGGMVHHRHRSS
Sbjct: 961 NEDLGPASPLDSTFYRSLLEDDDMGDLVDAEEYLVPQQGFFCPDPAPGAGGMVHHRHRSS 1020
Query: 1021 STRSGGGDLTLGLEPSEEEAPRSPLAPSEGAGSDVFDGDLGMGAAKGLQSLPTHDPSPLQ 1080
STRSGGGDLTLGLEPSEEEAPRSPLAPSEGAGSDVFDGDLGMGAAKGLQSLPTHDPSPLQ
Sbjct: 1021 STRSGGGDLTLGLEPSEEEAPRSPLAPSEGAGSDVFDGDLGMGAAKGLQSLPTHDPSPLQ 1080
Query: 1081 RYSEDPTVPLPSETDGYVAPLTCSPQPEYVNQPDVRPQPPSPREGPLPAARPAGATLERP 1140
RYSEDPTVPLPSETDGYVAPLTCSPQPEYVNQPDVRPQPPSPREGPLPAARPAGATLERP
Sbjct: 1081 RYSEDPTVPLPSETDGYVAPLTCSPQPEYVNQPDVRPQPPSPREGPLPAARPAGATLERP 1140
Query: 1141 KTLSPGKNGVVKDVFAFGGAVENPEYLTPQGGAAPQPHPPPAFSPAFDNLYYWDQDPPER 1200
KTLSPGKNGVVKDVFAFGGAVENPEYLTPQGGAAPQPHPPPAFSPAFDNLYYWDQDPPER
Sbjct: 1141 KTLSPGKNGVVKDVFAFGGAVENPEYLTPQGGAAPQPHPPPAFSPAFDNLYYWDQDPPER 1200
Query: 1201 GAPPSTFKGTPTAENPEYLGLDVPV 1225
GAPPSTFKGTPTAENPEYLGLDVPV
Sbjct: 1201 GAPPSTFKGTPTAENPEYLGLDVPV 1225
>gi|54792096 erbB-2 isoform a [Homo sapiens]
Length = 1255
Score = 2568 bits (6657), Expect = 0.0
Identities = 1225/1225 (100%), Positives = 1225/1225 (100%)
Query: 1 MKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQDIQEVQGYVLIAHNQ 60
MKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQDIQEVQGYVLIAHNQ
Sbjct: 31 MKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQDIQEVQGYVLIAHNQ 90
Query: 61 VRQVPLQRLRIVRGTQLFEDNYALAVLDNGDPLNNTTPVTGASPGGLRELQLRSLTEILK 120
VRQVPLQRLRIVRGTQLFEDNYALAVLDNGDPLNNTTPVTGASPGGLRELQLRSLTEILK
Sbjct: 91 VRQVPLQRLRIVRGTQLFEDNYALAVLDNGDPLNNTTPVTGASPGGLRELQLRSLTEILK 150
Query: 121 GGVLIQRNPQLCYQDTILWKDIFHKNNQLALTLIDTNRSRACHPCSPMCKGSRCWGESSE 180
GGVLIQRNPQLCYQDTILWKDIFHKNNQLALTLIDTNRSRACHPCSPMCKGSRCWGESSE
Sbjct: 151 GGVLIQRNPQLCYQDTILWKDIFHKNNQLALTLIDTNRSRACHPCSPMCKGSRCWGESSE 210
Query: 181 DCQSLTRTVCAGGCARCKGPLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPA 240
DCQSLTRTVCAGGCARCKGPLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPA
Sbjct: 211 DCQSLTRTVCAGGCARCKGPLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPA 270
Query: 241 LVTYNTDTFESMPNPEGRYTFGASCVTACPYNYLSTDVGSCTLVCPLHNQEVTAEDGTQR 300
LVTYNTDTFESMPNPEGRYTFGASCVTACPYNYLSTDVGSCTLVCPLHNQEVTAEDGTQR
Sbjct: 271 LVTYNTDTFESMPNPEGRYTFGASCVTACPYNYLSTDVGSCTLVCPLHNQEVTAEDGTQR 330
Query: 301 CEKCSKPCARVCYGLGMEHLREVRAVTSANIQEFAGCKKIFGSLAFLPESFDGDPASNTA 360
CEKCSKPCARVCYGLGMEHLREVRAVTSANIQEFAGCKKIFGSLAFLPESFDGDPASNTA
Sbjct: 331 CEKCSKPCARVCYGLGMEHLREVRAVTSANIQEFAGCKKIFGSLAFLPESFDGDPASNTA 390
Query: 361 PLQPEQLQVFETLEEITGYLYISAWPDSLPDLSVFQNLQVIRGRILHNGAYSLTLQGLGI 420
PLQPEQLQVFETLEEITGYLYISAWPDSLPDLSVFQNLQVIRGRILHNGAYSLTLQGLGI
Sbjct: 391 PLQPEQLQVFETLEEITGYLYISAWPDSLPDLSVFQNLQVIRGRILHNGAYSLTLQGLGI 450
Query: 421 SWLGLRSLRELGSGLALIHHNTHLCFVHTVPWDQLFRNPHQALLHTANRPEDECVGEGLA 480
SWLGLRSLRELGSGLALIHHNTHLCFVHTVPWDQLFRNPHQALLHTANRPEDECVGEGLA
Sbjct: 451 SWLGLRSLRELGSGLALIHHNTHLCFVHTVPWDQLFRNPHQALLHTANRPEDECVGEGLA 510
Query: 481 CHQLCARGHCWGPGPTQCVNCSQFLRGQECVEECRVLQGLPREYVNARHCLPCHPECQPQ 540
CHQLCARGHCWGPGPTQCVNCSQFLRGQECVEECRVLQGLPREYVNARHCLPCHPECQPQ
Sbjct: 511 CHQLCARGHCWGPGPTQCVNCSQFLRGQECVEECRVLQGLPREYVNARHCLPCHPECQPQ 570
Query: 541 NGSVTCFGPEADQCVACAHYKDPPFCVARCPSGVKPDLSYMPIWKFPDEEGACQPCPINC 600
NGSVTCFGPEADQCVACAHYKDPPFCVARCPSGVKPDLSYMPIWKFPDEEGACQPCPINC
Sbjct: 571 NGSVTCFGPEADQCVACAHYKDPPFCVARCPSGVKPDLSYMPIWKFPDEEGACQPCPINC 630
Query: 601 THSCVDLDDKGCPAEQRASPLTSIISAVVGILLVVVLGVVFGILIKRRQQKIRKYTMRRL 660
THSCVDLDDKGCPAEQRASPLTSIISAVVGILLVVVLGVVFGILIKRRQQKIRKYTMRRL
Sbjct: 631 THSCVDLDDKGCPAEQRASPLTSIISAVVGILLVVVLGVVFGILIKRRQQKIRKYTMRRL 690
Query: 661 LQETELVEPLTPSGAMPNQAQMRILKETELRKVKVLGSGAFGTVYKGIWIPDGENVKIPV 720
LQETELVEPLTPSGAMPNQAQMRILKETELRKVKVLGSGAFGTVYKGIWIPDGENVKIPV
Sbjct: 691 LQETELVEPLTPSGAMPNQAQMRILKETELRKVKVLGSGAFGTVYKGIWIPDGENVKIPV 750
Query: 721 AIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQLVTQLMPYGCLLDHV 780
AIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQLVTQLMPYGCLLDHV
Sbjct: 751 AIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQLVTQLMPYGCLLDHV 810
Query: 781 RENRGRLGSQDLLNWCMQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLL 840
RENRGRLGSQDLLNWCMQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLL
Sbjct: 811 RENRGRLGSQDLLNWCMQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLL 870
Query: 841 DIDETEYHADGGKVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPARE 900
DIDETEYHADGGKVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPARE
Sbjct: 871 DIDETEYHADGGKVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPARE 930
Query: 901 IPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSEFSRMARDPQRFVVIQ 960
IPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSEFSRMARDPQRFVVIQ
Sbjct: 931 IPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSEFSRMARDPQRFVVIQ 990
Query: 961 NEDLGPASPLDSTFYRSLLEDDDMGDLVDAEEYLVPQQGFFCPDPAPGAGGMVHHRHRSS 1020
NEDLGPASPLDSTFYRSLLEDDDMGDLVDAEEYLVPQQGFFCPDPAPGAGGMVHHRHRSS
Sbjct: 991 NEDLGPASPLDSTFYRSLLEDDDMGDLVDAEEYLVPQQGFFCPDPAPGAGGMVHHRHRSS 1050
Query: 1021 STRSGGGDLTLGLEPSEEEAPRSPLAPSEGAGSDVFDGDLGMGAAKGLQSLPTHDPSPLQ 1080
STRSGGGDLTLGLEPSEEEAPRSPLAPSEGAGSDVFDGDLGMGAAKGLQSLPTHDPSPLQ
Sbjct: 1051 STRSGGGDLTLGLEPSEEEAPRSPLAPSEGAGSDVFDGDLGMGAAKGLQSLPTHDPSPLQ 1110
Query: 1081 RYSEDPTVPLPSETDGYVAPLTCSPQPEYVNQPDVRPQPPSPREGPLPAARPAGATLERP 1140
RYSEDPTVPLPSETDGYVAPLTCSPQPEYVNQPDVRPQPPSPREGPLPAARPAGATLERP
Sbjct: 1111 RYSEDPTVPLPSETDGYVAPLTCSPQPEYVNQPDVRPQPPSPREGPLPAARPAGATLERP 1170
Query: 1141 KTLSPGKNGVVKDVFAFGGAVENPEYLTPQGGAAPQPHPPPAFSPAFDNLYYWDQDPPER 1200
KTLSPGKNGVVKDVFAFGGAVENPEYLTPQGGAAPQPHPPPAFSPAFDNLYYWDQDPPER
Sbjct: 1171 KTLSPGKNGVVKDVFAFGGAVENPEYLTPQGGAAPQPHPPPAFSPAFDNLYYWDQDPPER 1230
Query: 1201 GAPPSTFKGTPTAENPEYLGLDVPV 1225
GAPPSTFKGTPTAENPEYLGLDVPV
Sbjct: 1231 GAPPSTFKGTPTAENPEYLGLDVPV 1255
>gi|29725609 epidermal growth factor receptor isoform a precursor
[Homo sapiens]
Length = 1210
Score = 1186 bits (3068), Expect = 0.0
Identities = 616/1221 (50%), Positives = 788/1221 (64%), Gaps = 78/1221 (6%)
Query: 10 ETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQDIQEVQGYVLIAHNQVRQVPLQRL 69
E H L+ ++ C+VV GNLE+TY+ N LSFL+ IQEV GYVLIA N V ++PL+ L
Sbjct: 45 EDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENL 104
Query: 70 RIVRGTQLFEDNYALAVLDNGDPLNNTTPVTGASPGGLRELQLRSLTEILKGGVLIQRNP 129
+I+RG +E++YALAVL N D A+ GL+EL +R+L EIL G V NP
Sbjct: 105 QIIRGNMYYENSYALAVLSNYD----------ANKTGLKELPMRNLQEILHGAVRFSNNP 154
Query: 130 QLCYQDTILWKDIFHKNNQLALTLIDTNRSRACHPCSPMCKGSRCWGESSEDCQSLTRTV 189
LC ++I W+DI + +++ N +C C P C CWG E+CQ LT+ +
Sbjct: 155 ALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKII 214
Query: 190 CAGGCA-RCKGPLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDT 248
CA C+ RC+G P+DCCH QCAAGCTGP+ SDCL C F C+ CP L+ YN T
Sbjct: 215 CAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTT 274
Query: 249 FESMPNPEGRYTFGASCVTACPYNYLSTDVGSCTLVCPLHNQEVTAEDGTQRCEKCSKPC 308
++ NPEG+Y+FGA+CV CP NY+ TD GSC C + E+ EDG ++C+KC PC
Sbjct: 275 YQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEME-EDGVRKCKKCEGPC 333
Query: 309 ARVCYGLGMEHLREVRAVTSANIQEFAGCKKIFGSLAFLPESFDGDPASNTAPLQPEQLQ 368
+VC G+G+ ++ ++ + NI+ F C I G L LP +F GD ++T PL P++L
Sbjct: 334 RKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELD 393
Query: 369 VFETLEEITGYLYISAWPDSLPDLSVFQNLQVIRGRILHNGAYSLTLQGLGISWLGLRSL 428
+ +T++EITG+L I AWP++ DL F+NL++IRGR +G +SL + L I+ LGLRSL
Sbjct: 394 ILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSL 453
Query: 429 RELGSGLALIHHNTHLCFVHTVPWDQLFRNPHQALLHTANRPEDECVGEGLACHQLCARG 488
+E+ G +I N +LC+ +T+ W +LF Q +NR E+ C G CH LC+
Sbjct: 454 KEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPE 513
Query: 489 HCWGPGPTQCVNCSQFLRGQECVEECRVLQGLPREYVNARHCLPCHPECQPQNGSVTCFG 548
CWGP P CV+C RG+ECV++C +L+G PRE+V C+ CHPEC PQ ++TC G
Sbjct: 514 GCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTG 573
Query: 549 PEADQCVACAHYKDPPFCVARCPSGVKPDLSYMPIWKFPDEEGACQPCPINCTHSCVDLD 608
D C+ CAHY D P CV CP+GV + + + +WK+ D C C NCT+ C
Sbjct: 574 RGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTL-VWKYADAGHVCHLCHPNCTYGCTGPG 632
Query: 609 DKGCPAEQRASPLTSIISAVVGILLVVVLGVVFGI-LIKRRQQKIRKYTMRRLLQETELV 667
+GCP P SI + +VG LL++++ V GI L RR+ +RK T+RRLLQE ELV
Sbjct: 633 LEGCPTNGPKIP--SIATGMVGALLLLLV-VALGIGLFMRRRHIVRKRTLRRLLQERELV 689
Query: 668 EPLTPSGAMPNQAQMRILKETELRKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRE 727
EPLTPSG PNQA +RILKETE +K+KVLGSGAFGTVYKG+WIP+GE VKIPVAIK LRE
Sbjct: 690 EPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELRE 749
Query: 728 NTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQLVTQLMPYGCLLDHVRENRGRL 787
TSPKANKEILDEAYVMA V +P+V RLLGICLTSTVQL+TQLMP+GCLLD+VRE++ +
Sbjct: 750 ATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNI 809
Query: 788 GSQDLLNWCMQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEY 847
GSQ LLNWC+QIAKGM+YLED RLVHRDLAARNVLVK+P HVKITDFGLA+LL +E EY
Sbjct: 810 GSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEY 869
Query: 848 HADGGKVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEK 907
HA+GGKVPIKWMALESIL R +THQSDVWSYGVTVWELMTFG+KPYDGIPA EI +LEK
Sbjct: 870 HAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEK 929
Query: 908 GERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSEFSRMARDPQRFVVIQ-NEDLGP 966
GERLPQPPICTIDVYMIMVKCWMID++ RP+FREL+ EFS+MARDPQR++VIQ +E +
Sbjct: 930 GERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHL 989
Query: 967 ASPLDSTFYRSLLEDDDMGDLVDAEEYLVPQQGFFCPDPAPGAGGMVHHRHRSSSTRSGG 1026
SP DS FYR+L++++DM D+VDA+EYL+PQQGFF
Sbjct: 990 PSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFF------------------------- 1024
Query: 1027 GDLTLGLEPSEEEAPRSPLAPSEGAGSDVFDGDLGMGAAKGLQSLPTHDPSPLQRYSEDP 1086
S R+PL S A S+ + + GLQS P + S LQRYS DP
Sbjct: 1025 ---------SSPSTSRTPLLSSLSATSN--NSTVACIDRNGLQSCPIKEDSFLQRYSSDP 1073
Query: 1087 TVPLPSETDGYVAPLTCSPQPEYVNQPDVRPQPPSPREGPLPAARPAGATLERPKTLSPG 1146
T L ++ T P PEY+NQ V +P + P+ +P +P
Sbjct: 1074 TGALTEDS----IDDTFLPVPEYINQ-SVPKRPAGSVQNPVYHNQPLNP--------APS 1120
Query: 1147 KNGVVKDVFAFGGAVENPEYL-TPQGGAAPQPHPPPA-------FSPAFDNLYYWDQDPP 1198
++ +D AV NPEYL T Q PA + DN Y P
Sbjct: 1121 RDPHYQD--PHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFP 1178
Query: 1199 ERGAPPSTFKGTPTAENPEYL 1219
+ P FKG+ TAEN EYL
Sbjct: 1179 KEAKPNGIFKGS-TAENAEYL 1198
>gi|110825958 v-erb-a erythroblastic leukemia viral oncogene homolog 4
isoform JM-a/CVT-2 precursor [Homo sapiens]
Length = 1292
Score = 1129 bits (2921), Expect = 0.0
Identities = 597/1251 (47%), Positives = 779/1251 (62%), Gaps = 75/1251 (5%)
Query: 2 KLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQDIQEVQGYVLIAHNQV 61
KL + E LR Y+ C+VV GNLE+T + N LSFL+ ++EV GYVL+A NQ
Sbjct: 35 KLSSLSDLEQQYRALRKYYENCEVVMGNLEITSIEHNRDLSFLRSVREVTGYVLVALNQF 94
Query: 62 RQVPLQRLRIVRGTQLFEDNYALAVLDNGDPLNNTTPVTGASPGGLRELQLRSLTEILKG 121
R +PL+ LRI+RGT+L+ED YALA+ N N GL+EL L++LTEIL G
Sbjct: 95 RYLPLENLRIIRGTKLYEDRYALAIFLNYRKDGNF---------GLQELGLKNLTEILNG 145
Query: 122 GVLIQRNPQLCYQDTILWKDIFHKNNQLALTLIDTNRSRACHPCSPMCKGSRCWGESSED 181
GV + +N LCY DTI W+DI LTL+ TN S C C C G RCWG +
Sbjct: 146 GVYVDQNKFLCYADTIHWQDIVRNPWPSNLTLVSTNGSSGCGRCHKSCTG-RCWGPTENH 204
Query: 182 CQSLTRTVCAGGC-ARCKGPLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPA 240
CQ+LTRTVCA C RC GP +DCCH +CA GC+GPK +DC AC++FN SG C CP
Sbjct: 205 CQTLTRTVCAEQCDGRCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQ 264
Query: 241 LVTYNTDTFESMPNPEGRYTFGASCVTACPYNYLSTDVGSCTLVCPLHNQEVTAEDGTQR 300
YN TF+ N +YT+GA CV CP+N++ D SC CP EV E+G +
Sbjct: 265 TFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFV-VDSSSCVRACPSSKMEVE-ENGIKM 322
Query: 301 CEKCSKPCARVCYGLGMEHLREVRAVTSANIQEFAGCKKIFGSLAFLPESFDGDPASNTA 360
C+ C+ C + C G+G L + V S+NI +F C KI G+L FL GDP +
Sbjct: 323 CKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCTKINGNLIFLVTGIHGDPYNAIE 382
Query: 361 PLQPEQLQVFETLEEITGYLYISAWPDSLPDLSVFQNLQVIRGRILHNGAYSLTLQGLGI 420
+ PE+L VF T+ EITG+L I +WP ++ D SVF NL I GR+L++G L L+ GI
Sbjct: 383 AIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNLVTIGGRVLYSGLSLLILKQQGI 442
Query: 421 SWLGLRSLRELGSGLALIHHNTHLCFVHTVPWDQLFRNPHQALLHTANRPEDECVGEGLA 480
+ L +SL+E+ +G I N++LC+ HT+ W LF +Q ++ NR + C EG+
Sbjct: 443 TSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFSTINQRIVIRDNRKAENCTAEGMV 502
Query: 481 CHQLCARGHCWGPGPTQCVNCSQFLRGQECVEECRVLQGLPREYVNARHCLPCHPECQP- 539
C+ LC+ CWGPGP QC++C +F RG+ C+E C + G RE+ N C+ C P+C+
Sbjct: 503 CNHLCSSDGCWGPGPDQCLSCRRFSRGRICIESCNLYDGEFREFENGSICVECDPQCEKM 562
Query: 540 QNGSVTCFGPEADQCVACAHYKDPPFCVARCPSGVKPDLSYMPIWKFPDEEGACQPCPIN 599
++G +TC GP D C C+H+KD P CV +CP G++ S+ I+K+ D + C PC N
Sbjct: 563 EDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGANSF--IFKYADPDRECHPCHPN 620
Query: 600 CTHSCVDLDDKGC-----------PAEQRASPLTSIISAVV--GILLVVVLGVVFGILIK 646
CT C C P R T +I+A V G+ ++V++G+ F + ++
Sbjct: 621 CTQGCNGPTSHDCIYYPWTGHSTLPQHAR----TPLIAAGVIGGLFILVIVGLTFAVYVR 676
Query: 647 RRQQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETELRKVKVLGSGAFGTVYK 706
R+ K +K +RR L ETELVEPLTPSG PNQAQ+RILKETEL++VKVLGSGAFGTVYK
Sbjct: 677 RKSIK-KKRALRRFL-ETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYK 734
Query: 707 GIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQL 766
GIW+P+GE VKIPVAIK+L E T PKAN E +DEA +MA + P++ RLLG+CL+ T+QL
Sbjct: 735 GIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQL 794
Query: 767 VTQLMPYGCLLDHVRENRGRLGSQDLLNWCMQIAKGMSYLEDVRLVHRDLAARNVLVKSP 826
VTQLMP+GCLL++V E++ +GSQ LLNWC+QIAKGM YLE+ RLVHRDLAARNVLVKSP
Sbjct: 795 VTQLMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSP 854
Query: 827 NHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFTHQSDVWSYGVTVWELM 886
NHVKITDFGLARLL+ DE EY+ADGGK+PIKWMALE I R+FTHQSDVWSYGVT+WELM
Sbjct: 855 NHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELM 914
Query: 887 TFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSEF 946
TFG KPYDGIP REIPDLLEKGERLPQPPICTIDVYM+MVKCWMID++ RP+F+EL +EF
Sbjct: 915 TFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEF 974
Query: 947 SRMARDPQRFVVIQNED-LGPASPLDSTFYRSLLEDDDMGDLVDAEEYLVPQQGFFCPDP 1005
SRMARDPQR++VIQ +D + SP DS F+++LL+++D+ D++DAEEYLVP Q F P P
Sbjct: 975 SRMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAEEYLVP-QAFNIPPP 1033
Query: 1006 APGAGGMVHHRHRSSSTRSGGGDLTLGLE-PSEEEAPRSPLAP-SEGAGSDVFDGDLGMG 1063
+ + R GG G+ P P AP ++GA +++FD G
Sbjct: 1034 IYTSRARIDSNRNQFVYRDGGFAAEQGVSVPYRAPTSTIPEAPVAQGATAEIFDDSCCNG 1093
Query: 1064 AAKGLQSLPTHDPSPLQRYSEDPTVPLPS-------ETDGYVAPLTCSPQPEYVNQPDVR 1116
+ + + S QRYS DPTV P + +GY+ P+ P+ EY+N +
Sbjct: 1094 TLRKPVAPHVQEDSSTQRYSADPTVFAPERSPRGELDEEGYMTPMRDKPKQEYLNPVEEN 1153
Query: 1117 PQPPSPREGPLPAARPAGATLERPKTLSPGKNGVVKDVFAFGGAVENPEYLTPQGGAAPQ 1176
P + G L A L+ P+ NG K A V P YL +
Sbjct: 1154 PFVSRRKNGDLQA-------LDNPE-YHNASNGPPK---AEDEYVNEPLYLNTFANTLGK 1202
Query: 1177 PH--------PPPAFSPAFDNLYYWDQDPPERGAPPSTFKGTPTAENPEYL 1219
P AFDN YW+ P R T ++P+YL
Sbjct: 1203 AEYLKNNILSMPEKAKKAFDNPDYWNHSLPPRS----------TLQHPDYL 1243
>gi|4885215 v-erb-a erythroblastic leukemia viral oncogene homolog 4
isoform JM-a/CVT-1 precursor [Homo sapiens]
Length = 1308
Score = 1120 bits (2898), Expect = 0.0
Identities = 596/1272 (46%), Positives = 782/1272 (61%), Gaps = 101/1272 (7%)
Query: 2 KLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQDIQEVQGYVLIAHNQV 61
KL + E LR Y+ C+VV GNLE+T + N LSFL+ ++EV GYVL+A NQ
Sbjct: 35 KLSSLSDLEQQYRALRKYYENCEVVMGNLEITSIEHNRDLSFLRSVREVTGYVLVALNQF 94
Query: 62 RQVPLQRLRIVRGTQLFEDNYALAVLDNGDPLNNTTPVTGASPGGLRELQLRSLTEILKG 121
R +PL+ LRI+RGT+L+ED YALA+ N N GL+EL L++LTEIL G
Sbjct: 95 RYLPLENLRIIRGTKLYEDRYALAIFLNYRKDGNF---------GLQELGLKNLTEILNG 145
Query: 122 GVLIQRNPQLCYQDTILWKDIFHKNNQLALTLIDTNRSRACHPCSPMCKGSRCWGESSED 181
GV + +N LCY DTI W+DI LTL+ TN S C C C G RCWG +
Sbjct: 146 GVYVDQNKFLCYADTIHWQDIVRNPWPSNLTLVSTNGSSGCGRCHKSCTG-RCWGPTENH 204
Query: 182 CQSLTRTVCAGGC-ARCKGPLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPA 240
CQ+LTRTVCA C RC GP +DCCH +CA GC+GPK +DC AC++FN SG C CP
Sbjct: 205 CQTLTRTVCAEQCDGRCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQ 264
Query: 241 LVTYNTDTFESMPNPEGRYTFGASCVTACPYNYLSTDVGSCTLVCPLHNQEVTAEDGTQR 300
YN TF+ N +YT+GA CV CP+N++ D SC CP EV E+G +
Sbjct: 265 TFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFV-VDSSSCVRACPSSKMEVE-ENGIKM 322
Query: 301 CEKCSKPCARVCYGLGMEHLREVRAVTSANIQEFAGCKKIFGSLAFLPESFDGDPASNTA 360
C+ C+ C + C G+G L + V S+NI +F C KI G+L FL GDP +
Sbjct: 323 CKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCTKINGNLIFLVTGIHGDPYNAIE 382
Query: 361 PLQPEQLQVFETLEEITGYLYISAWPDSLPDLSVFQNLQVIRGRILHNGAYSLTLQGLGI 420
+ PE+L VF T+ EITG+L I +WP ++ D SVF NL I GR+L++G L L+ GI
Sbjct: 383 AIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNLVTIGGRVLYSGLSLLILKQQGI 442
Query: 421 SWLGLRSLRELGSGLALIHHNTHLCFVHTVPWDQLFRNPHQALLHTANRPEDECVGEGLA 480
+ L +SL+E+ +G I N++LC+ HT+ W LF +Q ++ NR + C EG+
Sbjct: 443 TSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFSTINQRIVIRDNRKAENCTAEGMV 502
Query: 481 CHQLCARGHCWGPGPTQCVNCSQFLRGQECVEECRVLQGLPREYVNARHCLPCHPECQP- 539
C+ LC+ CWGPGP QC++C +F RG+ C+E C + G RE+ N C+ C P+C+
Sbjct: 503 CNHLCSSDGCWGPGPDQCLSCRRFSRGRICIESCNLYDGEFREFENGSICVECDPQCEKM 562
Query: 540 QNGSVTCFGPEADQCVACAHYKDPPFCVARCPSGVKPDLSYMPIWKFPDEEGACQPCPIN 599
++G +TC GP D C C+H+KD P CV +CP G++ S+ I+K+ D + C PC N
Sbjct: 563 EDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGANSF--IFKYADPDRECHPCHPN 620
Query: 600 CTHSCVDLDDKGC-----------PAEQRASPLTSIISAVV--GILLVVVLGVVFGILIK 646
CT C C P R T +I+A V G+ ++V++G+ F + ++
Sbjct: 621 CTQGCNGPTSHDCIYYPWTGHSTLPQHAR----TPLIAAGVIGGLFILVIVGLTFAVYVR 676
Query: 647 RRQQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETELRKVKVLGSGAFGTVYK 706
R+ K +K +RR L ETELVEPLTPSG PNQAQ+RILKETEL++VKVLGSGAFGTVYK
Sbjct: 677 RKSIK-KKRALRRFL-ETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYK 734
Query: 707 GIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQL 766
GIW+P+GE VKIPVAIK+L E T PKAN E +DEA +MA + P++ RLLG+CL+ T+QL
Sbjct: 735 GIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQL 794
Query: 767 VTQLMPYGCLLDHVRENRGRLGSQDLLNWCMQIAKGMSYLEDVRLVHRDLAARNVLVKSP 826
VTQLMP+GCLL++V E++ +GSQ LLNWC+QIAKGM YLE+ RLVHRDLAARNVLVKSP
Sbjct: 795 VTQLMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSP 854
Query: 827 NHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFTHQSDVWSYGVTVWELM 886
NHVKITDFGLARLL+ DE EY+ADGGK+PIKWMALE I R+FTHQSDVWSYGVT+WELM
Sbjct: 855 NHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELM 914
Query: 887 TFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSEF 946
TFG KPYDGIP REIPDLLEKGERLPQPPICTIDVYM+MVKCWMID++ RP+F+EL +EF
Sbjct: 915 TFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEF 974
Query: 947 SRMARDPQRFVVIQNED-LGPASPLDSTFYRSLLEDDDMGDLVDAEEYLVPQQGFFCPDP 1005
SRMARDPQR++VIQ +D + SP DS F+++LL+++D+ D++DAEEYLVP Q F P P
Sbjct: 975 SRMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAEEYLVP-QAFNIPPP 1033
Query: 1006 -----------------------APGAGGMVHHRHRSSSTRSGGGDLTLGLEPSEEEAPR 1042
P +G +R + G +++ P
Sbjct: 1034 IYTSRARIDSNRSEIGHSPPPAYTPMSGNQFVYRDGGFAAEQG---VSVPYRAPTSTIPE 1090
Query: 1043 SPLAPSEGAGSDVFDGDLGMGAAKGLQSLPTHDPSPLQRYSEDPTVPLPS-------ETD 1095
+P+A +GA +++FD G + + + S QRYS DPTV P + +
Sbjct: 1091 APVA--QGATAEIFDDSCCNGTLRKPVAPHVQEDSSTQRYSADPTVFAPERSPRGELDEE 1148
Query: 1096 GYVAPLTCSPQPEYVNQPDVRPQPPSPREGPLPAARPAGATLERPKTLSPGKNGVVKDVF 1155
GY+ P+ P+ EY+N + P + G L A L+ P+ NG K
Sbjct: 1149 GYMTPMRDKPKQEYLNPVEENPFVSRRKNGDLQA-------LDNPE-YHNASNGPPK--- 1197
Query: 1156 AFGGAVENPEYLTPQGGAAPQPH--------PPPAFSPAFDNLYYWDQDPPERGAPPSTF 1207
A V P YL + P AFDN YW+ P R
Sbjct: 1198 AEDEYVNEPLYLNTFANTLGKAEYLKNNILSMPEKAKKAFDNPDYWNHSLPPRS------ 1251
Query: 1208 KGTPTAENPEYL 1219
T ++P+YL
Sbjct: 1252 ----TLQHPDYL 1259
>gi|54792100 erbB-3 isoform 1 precursor [Homo sapiens]
Length = 1342
Score = 914 bits (2363), Expect = 0.0
Identities = 465/972 (47%), Positives = 616/972 (63%), Gaps = 31/972 (3%)
Query: 3 LRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQDIQEVQGYVLIAHNQVR 62
L + E L LY+ C+VV GNLE+ NA LSFLQ I+EV GYVL+A N+
Sbjct: 36 LSVTGDAENQYQTLYKLYERCEVVMGNLEIVLTGHNADLSFLQWIREVTGYVLVAMNEFS 95
Query: 63 QVPLQRLRIVRGTQLFEDNYALAVLDNGDPLNNTTPVTGASPGGLRELQLRSLTEILKGG 122
+PL LR+VRGTQ+++ +A+ V+ N NT S LR+L+L LTEIL GG
Sbjct: 96 TLPLPNLRVVRGTQVYDGKFAIFVMLN----YNTN-----SSHALRQLRLTQLTEILSGG 146
Query: 123 VLIQRNPQLCYQDTILWKDIFHKNNQLALTLIDTNRSRACHPCSPMCKGSRCWGESSEDC 182
V I++N +LC+ DTI W+DI + ++ + R+C PC +CKG RCWG SEDC
Sbjct: 147 VYIEKNDKLCHMDTIDWRDIVRDRDA---EIVVKDNGRSCPPCHEVCKG-RCWGPGSEDC 202
Query: 183 QSLTRTVCAGGC-ARCKGPLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPAL 241
Q+LT+T+CA C C GP P CCH++CA GC+GP+ +DC AC HFN SG C CP
Sbjct: 203 QTLTKTICAPQCNGHCFGPNPNQCCHDECAGGCSGPQDTDCFACRHFNDSGACVPRCPQP 262
Query: 242 VTYNTDTFESMPNPEGRYTFGASCVTACPYNYLSTDVGSCTLVCPLHNQEVTAEDGTQRC 301
+ YN TF+ PNP +Y +G CV +CP+N++ D SC CP EV ++G + C
Sbjct: 263 LVYNKLTFQLEPNPHTKYQYGGVCVASCPHNFV-VDQTSCVRACPPDKMEVD-KNGLKMC 320
Query: 302 EKCSKPCARVCYGLGMEHLREVRAVTSANIQEFAGCKKIFGSLAFLPESFDGDPASNTAP 361
E C C + C G G + V S+NI F C KI G+L FL +GDP
Sbjct: 321 EPCGGLCPKACEGTGSGS--RFQTVDSSNIDGFVNCTKILGNLDFLITGLNGDPWHKIPA 378
Query: 362 LQPEQLQVFETLEEITGYLYISAWPDSLPDLSVFQNLQVIRGRILHNGAYSLTL-QGLGI 420
L PE+L VF T+ EITGYL I +WP + + SVF NL I GR L+N +SL + + L +
Sbjct: 379 LDPEKLNVFRTVREITGYLNIQSWPPHMHNFSVFSNLTTIGGRSLYNRGFSLLIMKNLNV 438
Query: 421 SWLGLRSLRELGSGLALIHHNTHLCFVHTVPWDQLFRNPHQALLHTA-NRPEDECVGEGL 479
+ LG RSL+E+ +G I N LC+ H++ W ++ R P + L NRP +CV EG
Sbjct: 439 TSLGFRSLKEISAGRIYISANRQLCYHHSLNWTKVLRGPTEERLDIKHNRPRRDCVAEGK 498
Query: 480 ACHQLCARGHCWGPGPTQCVNCSQFLRGQECVEECRVLQGLPREYVNARHCLPCHPECQP 539
C LC+ G CWGPGP QC++C + RG CV C L G PRE+ + C CHPECQP
Sbjct: 499 VCDPLCSSGGCWGPGPGQCLSCRNYSRGGVCVTHCNFLNGEPREFAHEAECFSCHPECQP 558
Query: 540 QNGSVTCFGPEADQCVACAHYKDPPFCVARCPSGVKPDLSYMPIWKFPDEEGACQPCPIN 599
G+ TC G +D C CAH++D P CV+ CP GV PI+K+PD + C+PC N
Sbjct: 559 MEGTATCNGSGSDTCAQCAHFRDGPHCVSSCPHGVLGAKG--PIYKYPDVQNECRPCHEN 616
Query: 600 CTHSCVDLDDKGCPAEQRA----SPLTSIISAVVGILLVVVLGVVFGILIKRRQQKIR-K 654
CT C + + C + + LT ++ + G LVV+ ++ G + R ++I+ K
Sbjct: 617 CTQGCKGPELQDCLGQTLVLIGKTHLTMALTVIAG--LVVIFMMLGGTFLYWRGRRIQNK 674
Query: 655 YTMRRLLQETELVEPLTPSGAMPNQAQMRILKETELRKVKVLGSGAFGTVYKGIWIPDGE 714
MRR L+ E +EPL PS N+ RI KETELRK+KVLGSG FGTV+KG+WIP+GE
Sbjct: 675 RAMRRYLERGESIEPLDPS-EKANKVLARIFKETELRKLKVLGSGVFGTVHKGVWIPEGE 733
Query: 715 NVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQLVTQLMPYG 774
++KIPV IKV+ + + ++ + + D + + ++ RLLG+C S++QLVTQ +P G
Sbjct: 734 SIKIPVCIKVIEDKSGRQSFQAVTDHMLAIGSLDHAHIVRLLGLCPGSSLQLVTQYLPLG 793
Query: 775 CLLDHVRENRGRLGSQDLLNWCMQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDF 834
LLDHVR++RG LG Q LLNW +QIAKGM YLE+ +VHR+LAARNVL+KSP+ V++ DF
Sbjct: 794 SLLDHVRQHRGALGPQLLLNWGVQIAKGMYYLEEHGMVHRNLAARNVLLKSPSQVQVADF 853
Query: 835 GLARLLDIDETEYHADGGKVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYD 894
G+A LL D+ + K PIKWMALESI ++THQSDVWSYGVTVWELMTFGA+PY
Sbjct: 854 GVADLLPPDDKQLLYSEAKTPIKWMALESIHFGKYTHQSDVWSYGVTVWELMTFGAEPYA 913
Query: 895 GIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSEFSRMARDPQ 954
G+ E+PDLLEKGERL QP ICTIDVYM+MVKCWMID RP F+EL +EF+RMARDP
Sbjct: 914 GLRLAEVPDLLEKGERLAQPQICTIDVYMVMVKCWMIDENIRPTFKELANEFTRMARDPP 973
Query: 955 RFVVIQNEDLGP 966
R++VI+ E GP
Sbjct: 974 RYLVIKRES-GP 984
>gi|41327736 epidermal growth factor receptor isoform d precursor
[Homo sapiens]
Length = 705
Score = 568 bits (1464), Expect = e-161
Identities = 263/594 (44%), Positives = 367/594 (61%), Gaps = 13/594 (2%)
Query: 10 ETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQDIQEVQGYVLIAHNQVRQVPLQRL 69
E H L+ ++ C+VV GNLE+TY+ N LSFL+ IQEV GYVLIA N V ++PL+ L
Sbjct: 45 EDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENL 104
Query: 70 RIVRGTQLFEDNYALAVLDNGDPLNNTTPVTGASPGGLRELQLRSLTEILKGGVLIQRNP 129
+I+RG +E++YALAVL N D A+ GL+EL +R+L EIL G V NP
Sbjct: 105 QIIRGNMYYENSYALAVLSNYD----------ANKTGLKELPMRNLQEILHGAVRFSNNP 154
Query: 130 QLCYQDTILWKDIFHKNNQLALTLIDTNRSRACHPCSPMCKGSRCWGESSEDCQSLTRTV 189
LC ++I W+DI + +++ N +C C P C CWG E+CQ LT+ +
Sbjct: 155 ALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKII 214
Query: 190 CAGGCA-RCKGPLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDT 248
CA C+ RC+G P+DCCH QCAAGCTGP+ SDCL C F C+ CP L+ YN T
Sbjct: 215 CAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTT 274
Query: 249 FESMPNPEGRYTFGASCVTACPYNYLSTDVGSCTLVCPLHNQEVTAEDGTQRCEKCSKPC 308
++ NPEG+Y+FGA+CV CP NY+ TD GSC C + E+ EDG ++C+KC PC
Sbjct: 275 YQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEME-EDGVRKCKKCEGPC 333
Query: 309 ARVCYGLGMEHLREVRAVTSANIQEFAGCKKIFGSLAFLPESFDGDPASNTAPLQPEQLQ 368
+VC G+G+ ++ ++ + NI+ F C I G L LP +F GD ++T PL P++L
Sbjct: 334 RKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELD 393
Query: 369 VFETLEEITGYLYISAWPDSLPDLSVFQNLQVIRGRILHNGAYSLTLQGLGISWLGLRSL 428
+ +T++EITG+L I AWP++ DL F+NL++IRGR +G +SL + L I+ LGLRSL
Sbjct: 394 ILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSL 453
Query: 429 RELGSGLALIHHNTHLCFVHTVPWDQLFRNPHQALLHTANRPEDECVGEGLACHQLCARG 488
+E+ G +I N +LC+ +T+ W +LF Q +NR E+ C G CH LC+
Sbjct: 454 KEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPE 513
Query: 489 HCWGPGPTQCVNCSQFLRGQECVEECRVLQGLPREYVNARHCLPCHPECQPQNGSVTCFG 548
CWGP P CV+C RG+ECV++C +L+G PRE+V C+ CHPEC PQ ++TC G
Sbjct: 514 GCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTG 573
Query: 549 PEADQCVACAHYKDPPFCVARCPSGVKPDLSYMPIWKFPDEEGACQPCPINCTH 602
D C+ CAHY D P CV CP+GV + + + +WK+ D C C NCT+
Sbjct: 574 RGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTL-VWKYADAGHVCHLCHPNCTY 626
>gi|41327732 epidermal growth factor receptor isoform b precursor
[Homo sapiens]
Length = 628
Score = 568 bits (1464), Expect = e-161
Identities = 263/594 (44%), Positives = 367/594 (61%), Gaps = 13/594 (2%)
Query: 10 ETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQDIQEVQGYVLIAHNQVRQVPLQRL 69
E H L+ ++ C+VV GNLE+TY+ N LSFL+ IQEV GYVLIA N V ++PL+ L
Sbjct: 45 EDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENL 104
Query: 70 RIVRGTQLFEDNYALAVLDNGDPLNNTTPVTGASPGGLRELQLRSLTEILKGGVLIQRNP 129
+I+RG +E++YALAVL N D A+ GL+EL +R+L EIL G V NP
Sbjct: 105 QIIRGNMYYENSYALAVLSNYD----------ANKTGLKELPMRNLQEILHGAVRFSNNP 154
Query: 130 QLCYQDTILWKDIFHKNNQLALTLIDTNRSRACHPCSPMCKGSRCWGESSEDCQSLTRTV 189
LC ++I W+DI + +++ N +C C P C CWG E+CQ LT+ +
Sbjct: 155 ALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKII 214
Query: 190 CAGGCA-RCKGPLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDT 248
CA C+ RC+G P+DCCH QCAAGCTGP+ SDCL C F C+ CP L+ YN T
Sbjct: 215 CAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTT 274
Query: 249 FESMPNPEGRYTFGASCVTACPYNYLSTDVGSCTLVCPLHNQEVTAEDGTQRCEKCSKPC 308
++ NPEG+Y+FGA+CV CP NY+ TD GSC C + E+ EDG ++C+KC PC
Sbjct: 275 YQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEME-EDGVRKCKKCEGPC 333
Query: 309 ARVCYGLGMEHLREVRAVTSANIQEFAGCKKIFGSLAFLPESFDGDPASNTAPLQPEQLQ 368
+VC G+G+ ++ ++ + NI+ F C I G L LP +F GD ++T PL P++L
Sbjct: 334 RKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELD 393
Query: 369 VFETLEEITGYLYISAWPDSLPDLSVFQNLQVIRGRILHNGAYSLTLQGLGISWLGLRSL 428
+ +T++EITG+L I AWP++ DL F+NL++IRGR +G +SL + L I+ LGLRSL
Sbjct: 394 ILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSL 453
Query: 429 RELGSGLALIHHNTHLCFVHTVPWDQLFRNPHQALLHTANRPEDECVGEGLACHQLCARG 488
+E+ G +I N +LC+ +T+ W +LF Q +NR E+ C G CH LC+
Sbjct: 454 KEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPE 513
Query: 489 HCWGPGPTQCVNCSQFLRGQECVEECRVLQGLPREYVNARHCLPCHPECQPQNGSVTCFG 548
CWGP P CV+C RG+ECV++C +L+G PRE+V C+ CHPEC PQ ++TC G
Sbjct: 514 GCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTG 573
Query: 549 PEADQCVACAHYKDPPFCVARCPSGVKPDLSYMPIWKFPDEEGACQPCPINCTH 602
D C+ CAHY D P CV CP+GV + + + +WK+ D C C NCT+
Sbjct: 574 RGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTL-VWKYADAGHVCHLCHPNCTY 626
>gi|41327734 epidermal growth factor receptor isoform c precursor
[Homo sapiens]
Length = 405
Score = 351 bits (900), Expect = 3e-96
Identities = 165/370 (44%), Positives = 230/370 (62%), Gaps = 12/370 (3%)
Query: 10 ETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQDIQEVQGYVLIAHNQVRQVPLQRL 69
E H L+ ++ C+VV GNLE+TY+ N LSFL+ IQEV GYVLIA N V ++PL+ L
Sbjct: 45 EDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENL 104
Query: 70 RIVRGTQLFEDNYALAVLDNGDPLNNTTPVTGASPGGLRELQLRSLTEILKGGVLIQRNP 129
+I+RG +E++YALAVL N D A+ GL+EL +R+L EIL G V NP
Sbjct: 105 QIIRGNMYYENSYALAVLSNYD----------ANKTGLKELPMRNLQEILHGAVRFSNNP 154
Query: 130 QLCYQDTILWKDIFHKNNQLALTLIDTNRSRACHPCSPMCKGSRCWGESSEDCQSLTRTV 189
LC ++I W+DI + +++ N +C C P C CWG E+CQ LT+ +
Sbjct: 155 ALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKII 214
Query: 190 CAGGCA-RCKGPLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDT 248
CA C+ RC+G P+DCCH QCAAGCTGP+ SDCL C F C+ CP L+ YN T
Sbjct: 215 CAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTT 274
Query: 249 FESMPNPEGRYTFGASCVTACPYNYLSTDVGSCTLVCPLHNQEVTAEDGTQRCEKCSKPC 308
++ NPEG+Y+FGA+CV CP NY+ TD GSC C + E+ EDG ++C+KC PC
Sbjct: 275 YQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEM-EEDGVRKCKKCEGPC 333
Query: 309 ARVCYGLGMEHLREVRAVTSANIQEFAGCKKIFGSLAFLPESFDGDPASNTAPLQPEQLQ 368
+VC G+G+ ++ ++ + NI+ F C I G L LP +F GD ++T PL P++L
Sbjct: 334 RKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELD 393
Query: 369 VFETLEEITG 378
+ +T++EITG
Sbjct: 394 ILKTVKEITG 403
Score = 84.7 bits (208), Expect = 5e-16
Identities = 57/246 (23%), Positives = 101/246 (41%), Gaps = 43/246 (17%)
Query: 334 FAGCKKIFGSL--AFLPESFDGDPASNTAPLQPEQLQVFETLEEITGYLYISAWPDSLPD 391
F C+ + G+L ++ ++D L +T++E+ GY+ I+ + +
Sbjct: 55 FNNCEVVLGNLEITYVQRNYD--------------LSFLKTIQEVAGYVLIAL---NTVE 97
Query: 392 LSVFQNLQVIRGRILHNGAYSLTLQG------LGISWLGLRSLRELGSGLALIHHNTHLC 445
+NLQ+IRG + + +Y+L + G+ L +R+L+E+ G +N LC
Sbjct: 98 RIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALC 157
Query: 446 FVHTVPWDQLFRNPHQALLHTANRPEDECVGEGLACHQLCARGHCWGPGPTQCVNCSQFL 505
V ++ W + + L + +G C C G CWG G C ++ +
Sbjct: 158 NVESIQWRDIVSSD---FLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKII 214
Query: 506 RGQECVEECRVLQGLPREYVNARHCLPCHPECQPQNGSVTCFGPEADQCVACAHYKDPPF 565
Q+C CR + C CH +C + C GP C+ C ++D
Sbjct: 215 CAQQCSGRCR--------GKSPSDC--CHNQC-----AAGCTGPRESDCLVCRKFRDEAT 259
Query: 566 CVARCP 571
C CP
Sbjct: 260 CKDTCP 265
>gi|32967311 ephrin receptor EphA2 [Homo sapiens]
Length = 976
Score = 215 bits (547), Expect = 2e-55
Identities = 132/374 (35%), Positives = 200/374 (53%), Gaps = 16/374 (4%)
Query: 616 QRASPLTSIISAVVG------ILLVVVLGVVFGILIKRRQQKIRKYTMRRLLQETELVEP 669
Q SP S AV+G +LL+V+ GV F I +R+ Q+ R+ ++E ++P
Sbjct: 525 QTLSPEGSGNLAVIGGVAVGVVLLLVLAGVGFFIHRRRKNQRARQSPEDVYFSKSEQLKP 584
Query: 670 LTP-----SGAMPNQAQMRILKETE---LRKVKVLGSGAFGTVYKGIWIPDGENVKIPVA 721
L + PNQA ++ E + + KV+G+G FG VYKG+ ++PVA
Sbjct: 585 LKTYVDPHTYEDPNQAVLKFTTEIHPSCVTRQKVIGAGEFGEVYKGMLKTSSGKKEVPVA 644
Query: 722 IKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLT-STVQLVTQLMPYGCLLDHV 780
IK L+ + K + L EA +M + RL G+ + ++T+ M G L +
Sbjct: 645 IKTLKAGYTEKQRVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFL 704
Query: 781 RENRGRLGSQDLLNWCMQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLL 840
RE G L+ IA GM YL ++ VHRDLAARN+LV S K++DFGL+R+L
Sbjct: 705 REKDGEFSVLQLVGMLRGIAAGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVL 764
Query: 841 DID-ETEYHADGGKVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAR 899
+ D E Y GGK+PI+W A E+I R+FT SDVWS+G+ +WE+MT+G +PY +
Sbjct: 765 EDDPEATYTTSGGKIPIRWTAPEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNH 824
Query: 900 EIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSEFSRMARDPQRFVVI 959
E+ + G RLP P C +Y +M++CW + RP+F ++VS ++ R P +
Sbjct: 825 EVMKAINDGFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSILDKLIRAPDSLKTL 884
Query: 960 QNEDLGPASPLDST 973
+ D + L ST
Sbjct: 885 ADFDPRVSIRLPST 898
>gi|32528301 EPH receptor B4 precursor [Homo sapiens]
Length = 987
Score = 214 bits (545), Expect = 4e-55
Identities = 138/383 (36%), Positives = 209/383 (54%), Gaps = 21/383 (5%)
Query: 602 HSCVDLDDKGCPAEQRASPLTSIISAVVGILLVVVLGVVFGILIKRRQQKIR------KY 655
HS LD+ EQ A + AVVG++LV+V+ +V +L R+Q R K+
Sbjct: 523 HSQTQLDESEGWREQLALIAGT---AVVGVVLVLVV-IVVAVLCLRKQSNGREAEYSDKH 578
Query: 656 TMRRLLQETEL-VEPLTPSGAMPNQAQMRILKETELRKVK---VLGSGAFGTVYKGIWIP 711
+ T++ ++P T PN+A KE ++ VK V+G+G FG V +G
Sbjct: 579 GQYLIGHGTKVYIDPFTYED--PNEAVREFAKEIDVSYVKIEEVIGAGEFGEVCRGRLKA 636
Query: 712 DGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTST-VQLVTQL 770
G+ VAIK L+ + + +E L EA +M P + RL G+ S V ++T+
Sbjct: 637 PGKKESC-VAIKTLKGGYTERQRREFLSEASIMGQFEHPNIIRLEGVVTNSMPVMILTEF 695
Query: 771 MPYGCLLDHVRENRGRLGSQDLLNWCMQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVK 830
M G L +R N G+ L+ IA GM YL ++ VHRDLAARN+LV S K
Sbjct: 696 MENGALDSFLRLNDGQFTVIQLVGMLRGIASGMRYLAEMSYVHRDLAARNILVNSNLVCK 755
Query: 831 ITDFGLARLLD---IDETEYHADGGKVPIKWMALESILRRRFTHQSDVWSYGVTVWELMT 887
++DFGL+R L+ D T + GGK+PI+W A E+I R+FT SD WSYG+ +WE+M+
Sbjct: 756 VSDFGLSRFLEENSSDPTYTSSLGGKIPIRWTAPEAIAFRKFTSASDAWSYGIVMWEVMS 815
Query: 888 FGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSEFS 947
FG +PY + +++ + +E+ RLP PP C ++ +M+ CW D RPRF ++VS
Sbjct: 816 FGERPYWDMSNQDVINAIEQDYRLPPPPDCPTSLHQLMLDCWQKDRNARPRFPQVVSALD 875
Query: 948 RMARDPQRFVVIQNEDLGPASPL 970
+M R+P ++ E+ G + PL
Sbjct: 876 KMIRNPASLKIVARENGGASHPL 898
>gi|4758284 ephrin receptor EphB1 precursor [Homo sapiens]
Length = 984
Score = 211 bits (538), Expect = 3e-54
Identities = 129/361 (35%), Positives = 198/361 (54%), Gaps = 19/361 (5%)
Query: 626 SAVVGILLVVVLGVVFGILIKRR--------QQKIRKYTMRRLLQETEL-VEPLTPSGAM 676
SA G++ VV L + + ++R K++ Y+ R ++ ++P T
Sbjct: 545 SAAAGVVFVVSLVAISIVCSRKRAYSKEAVYSDKLQHYSTGRGSPGMKIYIDPFTYED-- 602
Query: 677 PNQAQMRILKETELRKVK---VLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKA 733
PN+A KE ++ VK V+G+G FG VYKG G+ +I VAIK L+ S K
Sbjct: 603 PNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKR-EIYVAIKTLKAGYSEKQ 661
Query: 734 NKEILDEAYVMAGVGSPYVSRLLGICLTST-VQLVTQLMPYGCLLDHVRENRGRLGSQDL 792
++ L EA +M P + RL G+ S V ++T+ M G L +R+N G+ L
Sbjct: 662 RRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQL 721
Query: 793 LNWCMQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETE--YHAD 850
+ IA GM YL ++ VHRDLAARN+LV S K++DFGL+R L D ++ Y +
Sbjct: 722 VGMLRGIAAGMKYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSS 781
Query: 851 -GGKVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGE 909
GGK+P++W A E+I R+FT SDVWSYG+ +WE+M+FG +PY + +++ + +E+
Sbjct: 782 LGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDY 841
Query: 910 RLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSEFSRMARDPQRFVVIQNEDLGPASP 969
RLP P C ++ +M+ CW D RPRF E+V+ +M R+P + P+ P
Sbjct: 842 RLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVATITAVPSQP 901
Query: 970 L 970
L
Sbjct: 902 L 902
>gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo
sapiens]
Length = 1015
Score = 206 bits (525), Expect = 8e-53
Identities = 132/380 (34%), Positives = 203/380 (53%), Gaps = 30/380 (7%)
Query: 625 ISAVVGILLVVVLGVVFGILIKRR------------QQKIRKYTMR-RLLQETELVEPLT 671
+S VG++L L VV G+L+ R ++K+ + +L ++P T
Sbjct: 577 VSVTVGVIL---LAVVIGVLLSGRRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHT 633
Query: 672 PSGAMPNQAQMRILKETELRKV---KVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLREN 728
PNQA KE E + +V+G+G FG V G G+ ++PVAIK L+
Sbjct: 634 YED--PNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKR-ELPVAIKTLKVG 690
Query: 729 TSPKANKEILDEAYVMAGVGSPYVSRLLGICLTST-VQLVTQLMPYGCLLDHVRENRGRL 787
+ K ++ L EA +M P + L G+ S V +VT+ M G L +++N G+
Sbjct: 691 YTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQF 750
Query: 788 GSQDLLNWCMQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDID-ETE 846
L+ I+ GM YL D+ VHRDLAARN+L+ S K++DFGL+R+L+ D E
Sbjct: 751 TVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAA 810
Query: 847 YHADGGKVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLE 906
Y GGK+PI+W A E+I R+FT SDVWSYG+ +WE++++G +PY + +++ +E
Sbjct: 811 YTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVE 870
Query: 907 KGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSEFSRMARDPQRFVVIQNED--- 963
+G RLP P C +Y +M+ CW + RP+F E+V+ ++ R+P + N
Sbjct: 871 EGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRV 930
Query: 964 ---LGPASPLDSTFYRSLLE 980
L SPL S YRS+ E
Sbjct: 931 SNLLAEHSPLGSGAYRSVGE 950
>gi|27886593 PTK2 protein tyrosine kinase 2 isoform b [Homo sapiens]
Length = 1074
Score = 206 bits (525), Expect = 8e-53
Identities = 109/277 (39%), Positives = 162/277 (58%), Gaps = 3/277 (1%)
Query: 676 MPNQAQMRILKETELRKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANK 735
MP+ I +E + + +G G FG V++GI++ EN + VAIK + TS +
Sbjct: 431 MPSTRDYEIQRE-RIELGRCIGEGQFGDVHQGIYMSP-ENPALAVAIKTCKNCTSDSVRE 488
Query: 736 EILDEAYVMAGVGSPYVSRLLGICLTSTVQLVTQLMPYGCLLDHVRENRGRLGSQDLLNW 795
+ L EA M P++ +L+G+ + V ++ +L G L ++ + L L+ +
Sbjct: 489 KFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILY 548
Query: 796 CMQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVP 855
Q++ ++YLE R VHRD+AARNVLV S + VK+ DFGL+R ++ D T Y A GK+P
Sbjct: 549 AYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYME-DSTYYKASKGKLP 607
Query: 856 IKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPP 915
IKWMA ESI RRFT SDVW +GV +WE++ G KP+ G+ ++ +E GERLP PP
Sbjct: 608 IKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPP 667
Query: 916 ICTIDVYMIMVKCWMIDSECRPRFRELVSEFSRMARD 952
C +Y +M KCW D RPRF EL ++ S + +
Sbjct: 668 NCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEE 704
>gi|24476013 PTK2 protein tyrosine kinase 2 isoform a [Homo sapiens]
Length = 1052
Score = 206 bits (525), Expect = 8e-53
Identities = 109/277 (39%), Positives = 162/277 (58%), Gaps = 3/277 (1%)
Query: 676 MPNQAQMRILKETELRKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANK 735
MP+ I +E + + +G G FG V++GI++ EN + VAIK + TS +
Sbjct: 409 MPSTRDYEIQRE-RIELGRCIGEGQFGDVHQGIYMSP-ENPALAVAIKTCKNCTSDSVRE 466
Query: 736 EILDEAYVMAGVGSPYVSRLLGICLTSTVQLVTQLMPYGCLLDHVRENRGRLGSQDLLNW 795
+ L EA M P++ +L+G+ + V ++ +L G L ++ + L L+ +
Sbjct: 467 KFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILY 526
Query: 796 CMQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVP 855
Q++ ++YLE R VHRD+AARNVLV S + VK+ DFGL+R ++ D T Y A GK+P
Sbjct: 527 AYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYME-DSTYYKASKGKLP 585
Query: 856 IKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPP 915
IKWMA ESI RRFT SDVW +GV +WE++ G KP+ G+ ++ +E GERLP PP
Sbjct: 586 IKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPP 645
Query: 916 ICTIDVYMIMVKCWMIDSECRPRFRELVSEFSRMARD 952
C +Y +M KCW D RPRF EL ++ S + +
Sbjct: 646 NCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEE 682
>gi|27886590 PTK2B protein tyrosine kinase 2 beta isoform a [Homo
sapiens]
Length = 1009
Score = 204 bits (520), Expect = 3e-52
Identities = 101/254 (39%), Positives = 160/254 (62%), Gaps = 2/254 (0%)
Query: 694 KVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVS 753
++LG G FG VY+G++ + + KI VA+K +++ + ++ + EA +M + P++
Sbjct: 429 RILGEGFFGEVYEGVYT-NHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIV 487
Query: 754 RLLGICLTSTVQLVTQLMPYGCLLDHVRENRGRLGSQDLLNWCMQIAKGMSYLEDVRLVH 813
+L+GI ++ +L PYG L ++ N+ L L+ + +QI K M+YLE + VH
Sbjct: 488 KLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVH 547
Query: 814 RDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFTHQS 873
RD+A RN+LV SP VK+ DFGL+R ++ DE Y A ++PIKWM+ ESI RRFT S
Sbjct: 548 RDIAVRNILVASPECVKLGDFGLSRYIE-DEDYYKASVTRLPIKWMSPESINFRRFTTAS 606
Query: 874 DVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDS 933
DVW + V +WE+++FG +P+ + +++ +LEKG+RLP+P +C +Y +M +CW D
Sbjct: 607 DVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDP 666
Query: 934 ECRPRFRELVSEFS 947
RPRF ELV S
Sbjct: 667 SDRPRFTELVCSLS 680
>gi|27886588 PTK2B protein tyrosine kinase 2 beta isoform b [Homo
sapiens]
Length = 967
Score = 204 bits (520), Expect = 3e-52
Identities = 101/254 (39%), Positives = 160/254 (62%), Gaps = 2/254 (0%)
Query: 694 KVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVS 753
++LG G FG VY+G++ + + KI VA+K +++ + ++ + EA +M + P++
Sbjct: 429 RILGEGFFGEVYEGVYT-NHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIV 487
Query: 754 RLLGICLTSTVQLVTQLMPYGCLLDHVRENRGRLGSQDLLNWCMQIAKGMSYLEDVRLVH 813
+L+GI ++ +L PYG L ++ N+ L L+ + +QI K M+YLE + VH
Sbjct: 488 KLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVH 547
Query: 814 RDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFTHQS 873
RD+A RN+LV SP VK+ DFGL+R ++ DE Y A ++PIKWM+ ESI RRFT S
Sbjct: 548 RDIAVRNILVASPECVKLGDFGLSRYIE-DEDYYKASVTRLPIKWMSPESINFRRFTTAS 606
Query: 874 DVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDS 933
DVW + V +WE+++FG +P+ + +++ +LEKG+RLP+P +C +Y +M +CW D
Sbjct: 607 DVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDP 666
Query: 934 ECRPRFRELVSEFS 947
RPRF ELV S
Sbjct: 667 SDRPRFTELVCSLS 680
>gi|27886586 PTK2B protein tyrosine kinase 2 beta isoform a [Homo
sapiens]
Length = 1009
Score = 204 bits (520), Expect = 3e-52
Identities = 101/254 (39%), Positives = 160/254 (62%), Gaps = 2/254 (0%)
Query: 694 KVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVS 753
++LG G FG VY+G++ + + KI VA+K +++ + ++ + EA +M + P++
Sbjct: 429 RILGEGFFGEVYEGVYT-NHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIV 487
Query: 754 RLLGICLTSTVQLVTQLMPYGCLLDHVRENRGRLGSQDLLNWCMQIAKGMSYLEDVRLVH 813
+L+GI ++ +L PYG L ++ N+ L L+ + +QI K M+YLE + VH
Sbjct: 488 KLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVH 547
Query: 814 RDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFTHQS 873
RD+A RN+LV SP VK+ DFGL+R ++ DE Y A ++PIKWM+ ESI RRFT S
Sbjct: 548 RDIAVRNILVASPECVKLGDFGLSRYIE-DEDYYKASVTRLPIKWMSPESINFRRFTTAS 606
Query: 874 DVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDS 933
DVW + V +WE+++FG +P+ + +++ +LEKG+RLP+P +C +Y +M +CW D
Sbjct: 607 DVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDP 666
Query: 934 ECRPRFRELVSEFS 947
RPRF ELV S
Sbjct: 667 SDRPRFTELVCSLS 680
>gi|27886584 PTK2B protein tyrosine kinase 2 beta isoform a [Homo
sapiens]
Length = 1009
Score = 204 bits (520), Expect = 3e-52
Identities = 101/254 (39%), Positives = 160/254 (62%), Gaps = 2/254 (0%)
Query: 694 KVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVS 753
++LG G FG VY+G++ + + KI VA+K +++ + ++ + EA +M + P++
Sbjct: 429 RILGEGFFGEVYEGVYT-NHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIV 487
Query: 754 RLLGICLTSTVQLVTQLMPYGCLLDHVRENRGRLGSQDLLNWCMQIAKGMSYLEDVRLVH 813
+L+GI ++ +L PYG L ++ N+ L L+ + +QI K M+YLE + VH
Sbjct: 488 KLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVH 547
Query: 814 RDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFTHQS 873
RD+A RN+LV SP VK+ DFGL+R ++ DE Y A ++PIKWM+ ESI RRFT S
Sbjct: 548 RDIAVRNILVASPECVKLGDFGLSRYIE-DEDYYKASVTRLPIKWMSPESINFRRFTTAS 606
Query: 874 DVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDS 933
DVW + V +WE+++FG +P+ + +++ +LEKG+RLP+P +C +Y +M +CW D
Sbjct: 607 DVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDP 666
Query: 934 ECRPRFRELVSEFS 947
RPRF ELV S
Sbjct: 667 SDRPRFTELVCSLS 680
>gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo
sapiens]
Length = 1037
Score = 204 bits (519), Expect = 4e-52
Identities = 118/315 (37%), Positives = 177/315 (56%), Gaps = 12/315 (3%)
Query: 677 PNQAQMRILKETELRKV---KVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKA 733
PNQA KE E + +V+G+G FG V G G+ ++PVAIK L+ + K
Sbjct: 659 PNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKR-ELPVAIKTLKVGYTEKQ 717
Query: 734 NKEILDEAYVMAGVGSPYVSRLLGICLTST-VQLVTQLMPYGCLLDHVRENRGRLGSQDL 792
++ L EA +M P + L G+ S V +VT+ M G L +++N G+ L
Sbjct: 718 RRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQL 777
Query: 793 LNWCMQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDID-ETEYHADG 851
+ I+ GM YL D+ VHRDLAARN+L+ S K++DFGL+R+L+ D E Y G
Sbjct: 778 VGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRG 837
Query: 852 GKVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERL 911
GK+PI+W A E+I R+FT SDVWSYG+ +WE++++G +PY + +++ +E+G RL
Sbjct: 838 GKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRL 897
Query: 912 PQPPICTIDVYMIMVKCWMIDSECRPRFRELVSEFSRMARDPQRFVVIQNED------LG 965
P P C +Y +M+ CW + RP+F E+V+ ++ R+P + N L
Sbjct: 898 PSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLA 957
Query: 966 PASPLDSTFYRSLLE 980
SPL S YRS+ E
Sbjct: 958 EHSPLGSGAYRSVGE 972
>gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo
sapiens]
Length = 987
Score = 202 bits (515), Expect = 1e-51
Identities = 126/351 (35%), Positives = 192/351 (54%), Gaps = 21/351 (5%)
Query: 621 LTSIISAVVGILLVVVLGVVFGILIKRRQ----------QKIRKYTMRRLLQETEL-VEP 669
L II + L+ ++ VV I+ RR+ K++ YT + ++ ++P
Sbjct: 541 LPLIIGSSAAGLVFLIAVVVIAIVCNRRRGFERADSEYTDKLQHYTSGHMTPGMKIYIDP 600
Query: 670 LTPSGAMPNQAQMRILKETELRKVK---VLGSGAFGTVYKGIWIPDGENVKIPVAIKVLR 726
T PN+A KE ++ VK V+G+G FG V G G+ +I VAIK L+
Sbjct: 601 FTYED--PNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKR-EIFVAIKTLK 657
Query: 727 ENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTST-VQLVTQLMPYGCLLDHVRENRG 785
+ K ++ L EA +M P V L G+ ST V ++T+ M G L +R+N G
Sbjct: 658 SGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDG 717
Query: 786 RLGSQDLLNWCMQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLD---I 842
+ L+ IA GM YL D+ VHRDLAARN+LV S K++DFGL+R L+
Sbjct: 718 QFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTS 777
Query: 843 DETEYHADGGKVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIP 902
D T A GGK+PI+W A E+I R+FT SDVWSYG+ +WE+M++G +PY + +++
Sbjct: 778 DPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVI 837
Query: 903 DLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSEFSRMARDP 953
+ +E+ RLP P C ++ +M+ CW D RP+F ++V+ +M R+P
Sbjct: 838 NAIEQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNP 888
>gi|4758280 ephrin receptor EphA4 [Homo sapiens]
Length = 986
Score = 202 bits (515), Expect = 1e-51
Identities = 128/365 (35%), Positives = 195/365 (53%), Gaps = 18/365 (4%)
Query: 618 ASPLTSIISAVVGILLVVVLGVVFGILIKRRQQKIRKYTMRRLLQETEL-------VEPL 670
A+ ++S ++LVV+L F +I RR+ K K + +E L V+P
Sbjct: 544 ANSTVLLVSVSGSVVLVVILIAAF--VISRRRSKYSK-AKQEADEEKHLNQGVRTYVDPF 600
Query: 671 TPSGAMPNQAQMRILKETE---LRKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRE 727
T PNQA KE + ++ KV+G G FG V G G+ +I VAIK L+
Sbjct: 601 TYED--PNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGRLKVPGKR-EICVAIKTLKA 657
Query: 728 NTSPKANKEILDEAYVMAGVGSPYVSRLLGICLT-STVQLVTQLMPYGCLLDHVRENRGR 786
+ K ++ L EA +M P + L G+ V ++T+ M G L +R+N GR
Sbjct: 658 GYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGR 717
Query: 787 LGSQDLLNWCMQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDID-ET 845
L+ I GM YL D+ VHRDLAARN+LV S K++DFG++R+L+ D E
Sbjct: 718 FTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEA 777
Query: 846 EYHADGGKVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLL 905
Y GGK+PI+W A E+I R+FT SDVWSYG+ +WE+M++G +PY + +++ +
Sbjct: 778 AYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAI 837
Query: 906 EKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSEFSRMARDPQRFVVIQNEDLG 965
E+G RLP P C I ++ +M+ CW + RP+F ++V+ ++ R+P E
Sbjct: 838 EEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGTESSR 897
Query: 966 PASPL 970
P + L
Sbjct: 898 PNTAL 902
>gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens]
Length = 998
Score = 202 bits (515), Expect = 1e-51
Identities = 130/395 (32%), Positives = 207/395 (52%), Gaps = 16/395 (4%)
Query: 609 DKGCPAEQRASPLTSIISAVVGILLVVVLGVVFGILIKRRQQKIRKYTMRRLLQE----- 663
++G A+Q L I+ + L+ VV VV I+ R+Q+ LQ+
Sbjct: 545 ERGSGAQQLQEQLPLIVGSATAGLVFVVAVVVIAIVCLRKQRHGSDSEYTEKLQQYIAPG 604
Query: 664 -TELVEPLTPSGAMPNQAQMRILKETELRKVK---VLGSGAFGTVYKGIWIPDGENVKIP 719
++P T PN+A KE ++ VK V+G+G FG V +G G ++
Sbjct: 605 MKVYIDPFTYED--PNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRR-EVF 661
Query: 720 VAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTST-VQLVTQLMPYGCLLD 778
VAIK L+ + + ++ L EA +M P + RL G+ S V ++T+ M L
Sbjct: 662 VAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDS 721
Query: 779 HVRENRGRLGSQDLLNWCMQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLAR 838
+R N G+ L+ IA GM YL ++ VHRDLAARN+LV S K++DFGL+R
Sbjct: 722 FLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSR 781
Query: 839 LLDIDETE--YHAD-GGKVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDG 895
L+ D ++ Y + GGK+PI+W A E+I R+FT SDVWSYG+ +WE+M++G +PY
Sbjct: 782 FLEDDPSDPTYTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWD 841
Query: 896 IPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSEFSRMARDPQR 955
+ +++ + +E+ RLP P C ++ +M+ CW+ D RP+F ++V+ ++ R+
Sbjct: 842 MSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKLIRNAAS 901
Query: 956 FVVIQNEDLGPASPLDSTFYRSLLEDDDMGDLVDA 990
VI + G + PL +GD +DA
Sbjct: 902 LKVIASAQSGMSQPLLDRTVPDYTTFTTVGDWLDA 936
>gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo
sapiens]
Length = 986
Score = 202 bits (514), Expect = 2e-51
Identities = 126/350 (36%), Positives = 191/350 (54%), Gaps = 20/350 (5%)
Query: 621 LTSIISAVVGILLVVVLGVVFGILIKRR---------QQKIRKYTMRRLLQETEL-VEPL 670
L II + L+ ++ VV I+ RR K++ YT + ++ ++P
Sbjct: 541 LPLIIGSSAAGLVFLIAVVVIAIVCNRRGFERADSEYTDKLQHYTSGHMTPGMKIYIDPF 600
Query: 671 TPSGAMPNQAQMRILKETELRKVK---VLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRE 727
T PN+A KE ++ VK V+G+G FG V G G+ +I VAIK L+
Sbjct: 601 TYED--PNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKR-EIFVAIKTLKS 657
Query: 728 NTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTST-VQLVTQLMPYGCLLDHVRENRGR 786
+ K ++ L EA +M P V L G+ ST V ++T+ M G L +R+N G+
Sbjct: 658 GYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQ 717
Query: 787 LGSQDLLNWCMQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLD---ID 843
L+ IA GM YL D+ VHRDLAARN+LV S K++DFGL+R L+ D
Sbjct: 718 FTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSD 777
Query: 844 ETEYHADGGKVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPD 903
T A GGK+PI+W A E+I R+FT SDVWSYG+ +WE+M++G +PY + +++ +
Sbjct: 778 PTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVIN 837
Query: 904 LLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSEFSRMARDP 953
+E+ RLP P C ++ +M+ CW D RP+F ++V+ +M R+P
Sbjct: 838 AIEQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNP 887
>gi|56549666 tyrosine kinase, non-receptor, 2 isoform 1 [Homo
sapiens]
Length = 1038
Score = 201 bits (511), Expect = 4e-51
Identities = 111/276 (40%), Positives = 167/276 (60%), Gaps = 7/276 (2%)
Query: 669 PLTPSGAMPNQAQMRILKETELRKVKVLGSGAFGTVYKGIW-IPDGENVKIPVAIKVLRE 727
P P+G P Q+ ++ E +LR ++ LG G+FG V +G W P G+ V VA+K L+
Sbjct: 105 PGGPAGEGPLQSLTCLIGEKDLRLLEKLGDGSFGVVRRGEWDAPSGKTVS--VAVKCLKP 162
Query: 728 N--TSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQLVTQLMPYGCLLDHVRENRG 785
+ + P+A + + E M + + RL G+ LT +++VT+L P G LLD +R+++G
Sbjct: 163 DVLSQPEAMDDFIREVNAMHSLDHRNLIRLYGVVLTPPMKMVTELAPLGSLLDRLRKHQG 222
Query: 786 RLGSQDLLNWCMQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDET 845
L + +Q+A+GM YLE R +HRDLAARN+L+ + + VKI DFGL R L ++
Sbjct: 223 HFLLGTLSRYAVQVAEGMGYLESKRFIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDD 282
Query: 846 EY-HADGGKVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDL 904
Y + KVP W A ES+ R F+H SD W +GVT+WE+ T+G +P+ G+ +I
Sbjct: 283 HYVMQEHRKVPFAWCAPESLKTRTFSHASDTWMFGVTLWEMFTYGQEPWIGLNGSQILHK 342
Query: 905 LEK-GERLPQPPICTIDVYMIMVKCWMIDSECRPRF 939
++K GERLP+P C D+Y +MV+CW E RP F
Sbjct: 343 IDKEGERLPRPEDCPQDIYNVMVQCWAHKPEDRPTF 378
Score = 39.7 bits (91), Expect = 0.018
Identities = 44/156 (28%), Positives = 59/156 (37%), Gaps = 24/156 (15%)
Query: 1047 PSEGAGSDVFDGDLGMGAAKGLQSLPTHDPSPLQRYSED------PTVPLPSE-TDGYVA 1099
PS +++F L + LQ+ P P+P D P VP+P T +V
Sbjct: 698 PSSAQTAEIFQA-LQQECMRQLQA-PAGSPAPSPSPGGDDKPQVPPRVPIPPRPTRPHVQ 755
Query: 1100 PLTCSPQPEYVNQ-------PDVRPQPPSPREG---PLPAARPAGATLERPKTLSPGKNG 1149
P E +Q P V P+ P +G P P P + L + SPGK
Sbjct: 756 LSPAPPGEEETSQWPGPASPPRVPPREPLSPQGSRTPSPLVPPGSSPLPPRLSSSPGKTM 815
Query: 1150 VVKDVFAFGGAVENPEYLTPQGGAAPQPHPPPAFSP 1185
FA +P+Y TPQ AP P P P
Sbjct: 816 PTTQSFA-----SDPKYATPQVIQAPGPRAGPCILP 846
Score = 32.3 bits (72), Expect = 2.8
Identities = 35/124 (28%), Positives = 46/124 (37%), Gaps = 33/124 (26%)
Query: 1104 SPQPEYVNQPDVRPQPPSPREGPLPAARPAGATLERPKTLSPGKNGVVKDVFAFGGAVEN 1163
SP P ++P V P+ P P P + LSP G ++ + G
Sbjct: 728 SPSPGGDDKPQVPPRVPIPPRPTRPHVQ-----------LSPAPPGE-EETSQWPGPASP 775
Query: 1164 P-----EYLTPQGGAAPQPHPPPAFSPAFDNLYYWDQDPPERGAPPSTFKGTPT----AE 1214
P E L+PQG P P PP SP PP + P K PT A
Sbjct: 776 PRVPPREPLSPQGSRTPSPLVPPGSSPL----------PPRLSSSPG--KTMPTTQSFAS 823
Query: 1215 NPEY 1218
+P+Y
Sbjct: 824 DPKY 827
>gi|58331191 tyrosine kinase, non-receptor, 2 isoform 2 [Homo
sapiens]
Length = 1086
Score = 201 bits (511), Expect = 4e-51
Identities = 111/276 (40%), Positives = 167/276 (60%), Gaps = 7/276 (2%)
Query: 669 PLTPSGAMPNQAQMRILKETELRKVKVLGSGAFGTVYKGIW-IPDGENVKIPVAIKVLRE 727
P P+G P Q+ ++ E +LR ++ LG G+FG V +G W P G+ V VA+K L+
Sbjct: 168 PGGPAGEGPLQSLTCLIGEKDLRLLEKLGDGSFGVVRRGEWDAPSGKTVS--VAVKCLKP 225
Query: 728 N--TSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQLVTQLMPYGCLLDHVRENRG 785
+ + P+A + + E M + + RL G+ LT +++VT+L P G LLD +R+++G
Sbjct: 226 DVLSQPEAMDDFIREVNAMHSLDHRNLIRLYGVVLTPPMKMVTELAPLGSLLDRLRKHQG 285
Query: 786 RLGSQDLLNWCMQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDET 845
L + +Q+A+GM YLE R +HRDLAARN+L+ + + VKI DFGL R L ++
Sbjct: 286 HFLLGTLSRYAVQVAEGMGYLESKRFIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDD 345
Query: 846 EY-HADGGKVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDL 904
Y + KVP W A ES+ R F+H SD W +GVT+WE+ T+G +P+ G+ +I
Sbjct: 346 HYVMQEHRKVPFAWCAPESLKTRTFSHASDTWMFGVTLWEMFTYGQEPWIGLNGSQILHK 405
Query: 905 LEK-GERLPQPPICTIDVYMIMVKCWMIDSECRPRF 939
++K GERLP+P C D+Y +MV+CW E RP F
Sbjct: 406 IDKEGERLPRPEDCPQDIYNVMVQCWAHKPEDRPTF 441
Score = 39.7 bits (91), Expect = 0.018
Identities = 44/156 (28%), Positives = 59/156 (37%), Gaps = 24/156 (15%)
Query: 1047 PSEGAGSDVFDGDLGMGAAKGLQSLPTHDPSPLQRYSED------PTVPLPSE-TDGYVA 1099
PS +++F L + LQ+ P P+P D P VP+P T +V
Sbjct: 776 PSSAQTAEIFQA-LQQECMRQLQA-PAGSPAPSPSPGGDDKPQVPPRVPIPPRPTRPHVQ 833
Query: 1100 PLTCSPQPEYVNQ-------PDVRPQPPSPREG---PLPAARPAGATLERPKTLSPGKNG 1149
P E +Q P V P+ P +G P P P + L + SPGK
Sbjct: 834 LSPAPPGEEETSQWPGPASPPRVPPREPLSPQGSRTPSPLVPPGSSPLPPRLSSSPGKTM 893
Query: 1150 VVKDVFAFGGAVENPEYLTPQGGAAPQPHPPPAFSP 1185
FA +P+Y TPQ AP P P P
Sbjct: 894 PTTQSFA-----SDPKYATPQVIQAPGPRAGPCILP 924
Score = 32.3 bits (72), Expect = 2.8
Identities = 35/124 (28%), Positives = 46/124 (37%), Gaps = 33/124 (26%)
Query: 1104 SPQPEYVNQPDVRPQPPSPREGPLPAARPAGATLERPKTLSPGKNGVVKDVFAFGGAVEN 1163
SP P ++P V P+ P P P + LSP G ++ + G
Sbjct: 806 SPSPGGDDKPQVPPRVPIPPRPTRPHVQ-----------LSPAPPGE-EETSQWPGPASP 853
Query: 1164 P-----EYLTPQGGAAPQPHPPPAFSPAFDNLYYWDQDPPERGAPPSTFKGTPT----AE 1214
P E L+PQG P P PP SP PP + P K PT A
Sbjct: 854 PRVPPREPLSPQGSRTPSPLVPPGSSPL----------PPRLSSSPG--KTMPTTQSFAS 901
Query: 1215 NPEY 1218
+P+Y
Sbjct: 902 DPKY 905
>gi|153266778 arg tyrosine kinase isoform c [Homo sapiens]
Length = 1167
Score = 201 bits (510), Expect = 5e-51
Identities = 120/290 (41%), Positives = 163/290 (56%), Gaps = 10/290 (3%)
Query: 685 LKETELRKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVM 744
++ T++ LG G +G VY G+W + + VA+K L+E+T +E L EA VM
Sbjct: 268 MERTDITMKHKLGGGQYGEVYVGVW----KKYSLTVAVKTLKEDTMEV--EEFLKEAAVM 321
Query: 745 AGVGSPYVSRLLGIC-LTSTVQLVTQLMPYGCLLDHVRE-NRGRLGSQDLLNWCMQIAKG 802
+ P + +LLG+C L +VT+ MPYG LLD++RE NR + + LL QI+
Sbjct: 322 KEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSA 381
Query: 803 MSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALE 862
M YLE +HRDLAARN LV + VK+ DFGL+RL+ D HA G K PIKW A E
Sbjct: 382 MEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTGDTYTAHA-GAKFPIKWTAPE 440
Query: 863 SILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVY 922
S+ F+ +SDVW++GV +WE+ T+G PY GI ++ DLLEKG R+ QP C VY
Sbjct: 441 SLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVY 500
Query: 923 MIMVKCWMIDSECRPRFRELVSEFSRMARDPQRFVVIQNEDLGPASPLDS 972
+M CW RP F E F M D + E+LG A+ S
Sbjct: 501 ELMRACWKWSPADRPSFAETHQAFETMFHDSSISEEVA-EELGRAASSSS 549
>gi|6382062 arg tyrosine kinase isoform b [Homo sapiens]
Length = 1182
Score = 201 bits (510), Expect = 5e-51
Identities = 120/290 (41%), Positives = 163/290 (56%), Gaps = 10/290 (3%)
Query: 685 LKETELRKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVM 744
++ T++ LG G +G VY G+W + + VA+K L+E+T +E L EA VM
Sbjct: 283 MERTDITMKHKLGGGQYGEVYVGVW----KKYSLTVAVKTLKEDTMEV--EEFLKEAAVM 336
Query: 745 AGVGSPYVSRLLGIC-LTSTVQLVTQLMPYGCLLDHVRE-NRGRLGSQDLLNWCMQIAKG 802
+ P + +LLG+C L +VT+ MPYG LLD++RE NR + + LL QI+
Sbjct: 337 KEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSA 396
Query: 803 MSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALE 862
M YLE +HRDLAARN LV + VK+ DFGL+RL+ D HA G K PIKW A E
Sbjct: 397 MEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTGDTYTAHA-GAKFPIKWTAPE 455
Query: 863 SILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVY 922
S+ F+ +SDVW++GV +WE+ T+G PY GI ++ DLLEKG R+ QP C VY
Sbjct: 456 SLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVY 515
Query: 923 MIMVKCWMIDSECRPRFRELVSEFSRMARDPQRFVVIQNEDLGPASPLDS 972
+M CW RP F E F M D + E+LG A+ S
Sbjct: 516 ELMRACWKWSPADRPSFAETHQAFETMFHDSSISEEVA-EELGRAASSSS 564
>gi|209862772 arg tyrosine kinase isoform d [Homo sapiens]
Length = 1064
Score = 201 bits (510), Expect = 5e-51
Identities = 120/290 (41%), Positives = 163/290 (56%), Gaps = 10/290 (3%)
Query: 685 LKETELRKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVM 744
++ T++ LG G +G VY G+W + + VA+K L+E+T +E L EA VM
Sbjct: 268 MERTDITMKHKLGGGQYGEVYVGVW----KKYSLTVAVKTLKEDTMEV--EEFLKEAAVM 321
Query: 745 AGVGSPYVSRLLGIC-LTSTVQLVTQLMPYGCLLDHVRE-NRGRLGSQDLLNWCMQIAKG 802
+ P + +LLG+C L +VT+ MPYG LLD++RE NR + + LL QI+
Sbjct: 322 KEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSA 381
Query: 803 MSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALE 862
M YLE +HRDLAARN LV + VK+ DFGL+RL+ D HA G K PIKW A E
Sbjct: 382 MEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTGDTYTAHA-GAKFPIKWTAPE 440
Query: 863 SILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVY 922
S+ F+ +SDVW++GV +WE+ T+G PY GI ++ DLLEKG R+ QP C VY
Sbjct: 441 SLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVY 500
Query: 923 MIMVKCWMIDSECRPRFRELVSEFSRMARDPQRFVVIQNEDLGPASPLDS 972
+M CW RP F E F M D + E+LG A+ S
Sbjct: 501 ELMRACWKWSPADRPSFAETHQAFETMFHDSSISEEVA-EELGRAASSSS 549
>gi|153266757 arg tyrosine kinase isoform a [Homo sapiens]
Length = 1146
Score = 201 bits (510), Expect = 5e-51
Identities = 120/290 (41%), Positives = 163/290 (56%), Gaps = 10/290 (3%)
Query: 685 LKETELRKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVM 744
++ T++ LG G +G VY G+W + + VA+K L+E+T +E L EA VM
Sbjct: 247 MERTDITMKHKLGGGQYGEVYVGVW----KKYSLTVAVKTLKEDTMEV--EEFLKEAAVM 300
Query: 745 AGVGSPYVSRLLGIC-LTSTVQLVTQLMPYGCLLDHVRE-NRGRLGSQDLLNWCMQIAKG 802
+ P + +LLG+C L +VT+ MPYG LLD++RE NR + + LL QI+
Sbjct: 301 KEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSA 360
Query: 803 MSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALE 862
M YLE +HRDLAARN LV + VK+ DFGL+RL+ D HA G K PIKW A E
Sbjct: 361 MEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTGDTYTAHA-GAKFPIKWTAPE 419
Query: 863 SILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVY 922
S+ F+ +SDVW++GV +WE+ T+G PY GI ++ DLLEKG R+ QP C VY
Sbjct: 420 SLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVY 479
Query: 923 MIMVKCWMIDSECRPRFRELVSEFSRMARDPQRFVVIQNEDLGPASPLDS 972
+M CW RP F E F M D + E+LG A+ S
Sbjct: 480 ELMRACWKWSPADRPSFAETHQAFETMFHDSSISEEVA-EELGRAASSSS 528
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.138 0.441
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 57,846,324
Number of Sequences: 37866
Number of extensions: 3351233
Number of successful extensions: 15380
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 580
Number of HSP's successfully gapped in prelim test: 678
Number of HSP's that attempted gapping in prelim test: 11540
Number of HSP's gapped (non-prelim): 3057
length of query: 1225
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1111
effective length of database: 13,930,794
effective search space: 15477112134
effective search space used: 15477112134
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.