Search of human proteins with 54633317

Search of human proteins with 54633317

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|54633317 thioredoxin domain containing 11 [Homo sapiens]
         (958 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|54633317 thioredoxin domain containing 11 [Homo sapiens]          1934   0.0  
gi|21361657 protein disulfide-isomerase A3 precursor [Homo sapiens]    64   5e-10
gi|4758304 protein disulfide isomerase A4 [Homo sapiens]               62   3e-09
gi|239745099 PREDICTED: similar to Golgin subfamily A member 8-l...    49   2e-05
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]            48   4e-05
gi|28372543 protein disulfide isomerase-like, testis expressed [...    48   5e-05
gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo sap...    47   9e-05
gi|239745111 PREDICTED: Golgin subfamily A member 8-like protein...    47   9e-05
gi|229577185 epidermal growth factor receptor pathway substrate ...    47   1e-04
gi|4503593 epidermal growth factor receptor pathway substrate 15...    47   1e-04
gi|113425145 PREDICTED: similar to Golgin subfamily A member 8-l...    46   1e-04
gi|239745130 PREDICTED: similar to Golgin subfamily A member 8-l...    46   1e-04
gi|24308127 DnaJ (Hsp40) homolog, subfamily C, member 10 [Homo s...    46   1e-04
gi|113425119 PREDICTED: similar to golgi autoantigen, golgin sub...    46   2e-04
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]         46   2e-04
gi|154354987 hook homolog 2 isoform 2 [Homo sapiens]                   46   2e-04
gi|154354985 hook homolog 2 isoform 1 [Homo sapiens]                   46   2e-04
gi|239745147 PREDICTED: similar to Golgin subfamily A member 8-l...    45   2e-04
gi|34577114 cytomatrix protein p110 [Homo sapiens]                     45   2e-04
gi|31542661 transmembrane protein 57 [Homo sapiens]                    45   2e-04
gi|20070125 prolyl 4-hydroxylase, beta subunit precursor [Homo s...    45   2e-04
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s...    45   3e-04
gi|113425137 PREDICTED: similar to Golgin subfamily A member 8-l...    45   3e-04
gi|113425121 PREDICTED: similar to Golgin subfamily A member 8-l...    45   3e-04
gi|156104908 myosin heavy chain 6 [Homo sapiens]                       45   3e-04
gi|42794779 myosin 18A isoform b [Homo sapiens]                        45   3e-04
gi|28416946 myosin 18A isoform a [Homo sapiens]                        45   3e-04
gi|194578896 golgi autoantigen, golgin subfamily a, 8E [Homo sap...    45   3e-04
gi|169208517 PREDICTED: similar to Golgin subfamily A member 8-l...    45   4e-04
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H...    45   4e-04

>gi|54633317 thioredoxin domain containing 11 [Homo sapiens]
          Length = 958

 Score = 1934 bits (5011), Expect = 0.0
 Identities = 958/958 (100%), Positives = 958/958 (100%)

Query: 1   MSECGGRGGGSSSSEDAEDEGGGGGGPAGSDCLSSSPTLATASSAGRLRRGLRGAFLMAR 60
           MSECGGRGGGSSSSEDAEDEGGGGGGPAGSDCLSSSPTLATASSAGRLRRGLRGAFLMAR
Sbjct: 1   MSECGGRGGGSSSSEDAEDEGGGGGGPAGSDCLSSSPTLATASSAGRLRRGLRGAFLMAR 60

Query: 61  QRPELLCGAVALGCALLLALKFTCSRAKDVIIPAKPPVSFFSLRSPVLDLFQGQLDYAEY 120
           QRPELLCGAVALGCALLLALKFTCSRAKDVIIPAKPPVSFFSLRSPVLDLFQGQLDYAEY
Sbjct: 61  QRPELLCGAVALGCALLLALKFTCSRAKDVIIPAKPPVSFFSLRSPVLDLFQGQLDYAEY 120

Query: 121 VRRDSEVVLLFFYAPWCGQSIAARAEIEQAASRLSDQVLFVAINCWWNQGKCRKQKHFFY 180
           VRRDSEVVLLFFYAPWCGQSIAARAEIEQAASRLSDQVLFVAINCWWNQGKCRKQKHFFY
Sbjct: 121 VRRDSEVVLLFFYAPWCGQSIAARAEIEQAASRLSDQVLFVAINCWWNQGKCRKQKHFFY 180

Query: 181 FPVIYLYHRSFGPIEYKGPMSAVYIEKFVRRVMKPLLYIPSQSELLDFLSNYEPGVLGYF 240
           FPVIYLYHRSFGPIEYKGPMSAVYIEKFVRRVMKPLLYIPSQSELLDFLSNYEPGVLGYF
Sbjct: 181 FPVIYLYHRSFGPIEYKGPMSAVYIEKFVRRVMKPLLYIPSQSELLDFLSNYEPGVLGYF 240

Query: 241 EFSGSPQPPGYLTFFTSALHSLKKDYLGTVRFGVITNKHLAKLVSLVHSGSVYLHRHFNT 300
           EFSGSPQPPGYLTFFTSALHSLKKDYLGTVRFGVITNKHLAKLVSLVHSGSVYLHRHFNT
Sbjct: 241 EFSGSPQPPGYLTFFTSALHSLKKDYLGTVRFGVITNKHLAKLVSLVHSGSVYLHRHFNT 300

Query: 301 SLVFPREVLNYTAENICKWALENQETLFRWLRPHGGKSLLLNNELKKGPALFLFIPFNPL 360
           SLVFPREVLNYTAENICKWALENQETLFRWLRPHGGKSLLLNNELKKGPALFLFIPFNPL
Sbjct: 301 SLVFPREVLNYTAENICKWALENQETLFRWLRPHGGKSLLLNNELKKGPALFLFIPFNPL 360

Query: 361 AESHPLIDEITEVALEYNNCHGDQVVERLLQHLRRVDAPVLESLALEVPAQLPDPPTITA 420
           AESHPLIDEITEVALEYNNCHGDQVVERLLQHLRRVDAPVLESLALEVPAQLPDPPTITA
Sbjct: 361 AESHPLIDEITEVALEYNNCHGDQVVERLLQHLRRVDAPVLESLALEVPAQLPDPPTITA 420

Query: 421 SPCCNTVVLPQWHSFSRTHNVCELCVNQTSGGMKPSSVSVPQCSFFEMAAALDSFYLKEQ 480
           SPCCNTVVLPQWHSFSRTHNVCELCVNQTSGGMKPSSVSVPQCSFFEMAAALDSFYLKEQ
Sbjct: 421 SPCCNTVVLPQWHSFSRTHNVCELCVNQTSGGMKPSSVSVPQCSFFEMAAALDSFYLKEQ 480

Query: 481 TFYHVASDSIECSNFLTSYSPFSYYTACCRTISRGVSGFIDSEQGVFEAPTVAFSSLEKK 540
           TFYHVASDSIECSNFLTSYSPFSYYTACCRTISRGVSGFIDSEQGVFEAPTVAFSSLEKK
Sbjct: 481 TFYHVASDSIECSNFLTSYSPFSYYTACCRTISRGVSGFIDSEQGVFEAPTVAFSSLEKK 540

Query: 541 CEVDAPSSVPHIEENRYLFPEVDMTSTNFTGLSCRTNKTLNIYLLDSNLFWLYAERLGAP 600
           CEVDAPSSVPHIEENRYLFPEVDMTSTNFTGLSCRTNKTLNIYLLDSNLFWLYAERLGAP
Sbjct: 541 CEVDAPSSVPHIEENRYLFPEVDMTSTNFTGLSCRTNKTLNIYLLDSNLFWLYAERLGAP 600

Query: 601 SSTQVKEFAAIVDVKEESHYILDPKQALMKLTLESFIQNFSVLYSPLKRHLIGSGSAQFP 660
           SSTQVKEFAAIVDVKEESHYILDPKQALMKLTLESFIQNFSVLYSPLKRHLIGSGSAQFP
Sbjct: 601 SSTQVKEFAAIVDVKEESHYILDPKQALMKLTLESFIQNFSVLYSPLKRHLIGSGSAQFP 660

Query: 661 SQHLITEVTTDTFWEVVLQKQDVLLLYYAPWCGFCPSLNHIFIQLARNLPMDTFTVARID 720
           SQHLITEVTTDTFWEVVLQKQDVLLLYYAPWCGFCPSLNHIFIQLARNLPMDTFTVARID
Sbjct: 661 SQHLITEVTTDTFWEVVLQKQDVLLLYYAPWCGFCPSLNHIFIQLARNLPMDTFTVARID 720

Query: 721 VSQNDLPWEFMVDRLPTVLFFPCNRKDLSVKYPEDVPITLPNLLRFILHHSDPASSPQNV 780
           VSQNDLPWEFMVDRLPTVLFFPCNRKDLSVKYPEDVPITLPNLLRFILHHSDPASSPQNV
Sbjct: 721 VSQNDLPWEFMVDRLPTVLFFPCNRKDLSVKYPEDVPITLPNLLRFILHHSDPASSPQNV 780

Query: 781 ANSPTKECLQSEAVLQRGHISHLEREIQKLRAEISSLQRAQVQVESQLSSARRDEHRLRQ 840
           ANSPTKECLQSEAVLQRGHISHLEREIQKLRAEISSLQRAQVQVESQLSSARRDEHRLRQ
Sbjct: 781 ANSPTKECLQSEAVLQRGHISHLEREIQKLRAEISSLQRAQVQVESQLSSARRDEHRLRQ 840

Query: 841 QQRALEEQHSLLHAHSEQLQALYEQKTRELQELARKLQELADASENLLTENTWLKILVAT 900
           QQRALEEQHSLLHAHSEQLQALYEQKTRELQELARKLQELADASENLLTENTWLKILVAT
Sbjct: 841 QQRALEEQHSLLHAHSEQLQALYEQKTRELQELARKLQELADASENLLTENTWLKILVAT 900

Query: 901 MERKLEGRDGAESLAAQREVHPKQPEPSATPQLPGSSPPPANVSATLVSERNKENRTD 958
           MERKLEGRDGAESLAAQREVHPKQPEPSATPQLPGSSPPPANVSATLVSERNKENRTD
Sbjct: 901 MERKLEGRDGAESLAAQREVHPKQPEPSATPQLPGSSPPPANVSATLVSERNKENRTD 958


>gi|21361657 protein disulfide-isomerase A3 precursor [Homo sapiens]
          Length = 505

 Score = 64.3 bits (155), Expect = 5e-10
 Identities = 42/124 (33%), Positives = 65/124 (52%), Gaps = 9/124 (7%)

Query: 633 LESFIQNFSVLYSPLKRHLIGSGSAQFPSQH--LITEVTTDTFWEVVL-QKQDVLLLYYA 689
           LE F+Q++      LKR+L    S   P  +   +  V  + F E+V  + +DVL+ +YA
Sbjct: 349 LERFLQDY--FDGNLKRYL---KSEPIPESNDGPVKVVVAENFDEIVNNENKDVLIEFYA 403

Query: 690 PWCGFCPSLNHIFIQLARNLPMD-TFTVARIDVSQNDLPWEFMVDRLPTVLFFPCNRKDL 748
           PWCG C +L   + +L   L  D    +A++D + ND+P  + V   PT+ F P N+K  
Sbjct: 404 PWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATANDVPSPYEVRGFPTIYFSPANKKLN 463

Query: 749 SVKY 752
             KY
Sbjct: 464 PKKY 467



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 41/163 (25%), Positives = 73/163 (44%), Gaps = 6/163 (3%)

Query: 105 SPVLDLFQGQLDYAEYVRRDSEVVLLFFYAPWCGQSIAARAEIEQAASRLSDQVLFVAIN 164
           S VL+L     +        + ++L+ F+APWCG       E E AA+RL   V    ++
Sbjct: 25  SDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKGIVPLAKVD 84

Query: 165 CWWNQGKCRKQKHFFYFPVIYLYHRSFGPIEYKGPMSAVYIEKFVRRVMKPL-LYIPSQS 223
           C  N   C K     Y P + ++        Y GP +A  I   +++   P  + + ++ 
Sbjct: 85  CTANTNTCNKYGVSGY-PTLKIFRDGEEAGAYDGPRTADGIVSHLKKQAGPASVPLRTEE 143

Query: 224 ELLDFLSNYEPGVLGYFEFSGSPQPPGYLTFFTSALHSLKKDY 266
           E   F+S+ +  ++G+F+ S S     +L     A  +L+ +Y
Sbjct: 144 EFKKFISDKDASIVGFFDDSFSEAHSEFL----KAASNLRDNY 182



 Score = 33.9 bits (76), Expect = 0.75
 Identities = 21/85 (24%), Positives = 35/85 (41%), Gaps = 2/85 (2%)

Query: 116 DYAEYVRRDSEVVLLFFYAPWCGQSIAARAEIEQAASRLSDQVLFVAINCWWNQGKCRKQ 175
           ++ E V  +++ VL+ FYAPWCG       + ++   +LS     V              
Sbjct: 385 NFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATANDVPSP 444

Query: 176 KHFFYFPVIYL--YHRSFGPIEYKG 198
                FP IY    ++   P +Y+G
Sbjct: 445 YEVRGFPTIYFSPANKKLNPKKYEG 469



 Score = 31.6 bits (70), Expect = 3.7
 Identities = 29/117 (24%), Positives = 50/117 (42%), Gaps = 9/117 (7%)

Query: 665 ITEVTTDTFWEVVLQKQD---VLLLYYAPWCGFCPSLNHIFIQLARNLPMDTFTVARIDV 721
           + E+T D F   +        +L+ ++APWCG C  L   +   A  L      +A++D 
Sbjct: 27  VLELTDDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRL-KGIVPLAKVDC 85

Query: 722 SQN-DLPWEFMVDRLPTVLFFPCNRKDLSVKYPEDVPITLPNLLRFILHHSDPASSP 777
           + N +   ++ V   PT+  F    +D       D P T   ++  +   + PAS P
Sbjct: 86  TANTNTCNKYGVSGYPTLKIF----RDGEEAGAYDGPRTADGIVSHLKKQAGPASVP 138


>gi|4758304 protein disulfide isomerase A4 [Homo sapiens]
          Length = 645

 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 38/111 (34%), Positives = 59/111 (53%), Gaps = 4/111 (3%)

Query: 668 VTTDTFWEVVLQ-KQDVLLLYYAPWCGFCPSLNHIFIQLARNLP-MDTFTVARIDVSQND 725
           V   TF  +V+  K+DVL+ +YAPWCG C  L  ++  LA+         +A++D + ND
Sbjct: 530 VVGKTFDSIVMDPKKDVLIEFYAPWCGHCKQLEPVYNSLAKKYKGQKGLVIAKMDATAND 589

Query: 726 LPWE-FMVDRLPTVLFFPCNRKDLSVKYPEDVPITLPNLLRFILHHSDPAS 775
           +P + + V+  PT+ F P   K   VK+ E     L +L +FI  H+   S
Sbjct: 590 VPSDRYKVEGFPTIYFAPSGDKKNPVKF-EGGDRDLEHLSKFIEEHATKLS 639



 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 32/119 (26%), Positives = 54/119 (45%), Gaps = 8/119 (6%)

Query: 660 PSQHLITEVTTDTFWEVVLQKQDVLLLYYAPWCGFCPSLNHIFIQLARNLPMDT--FTVA 717
           P   +   +T + F EVV     +L+ +YAPWCG C  L   + + A+ L   +    +A
Sbjct: 174 PPPEVTLVLTKENFDEVVNDADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLA 233

Query: 718 RID-VSQNDLPWEFMVDRLPTVLFFPCNRKDLSVKYPEDVPITLPNLLRFILHHSDPAS 775
           ++D  ++ DL   F V   PT+  F   R      Y  + P     ++ +++  S P S
Sbjct: 234 KVDATAETDLAKRFDVSGYPTLKIFRKGR-----PYDYNGPREKYGIVDYMIEQSGPPS 287



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 36/150 (24%), Positives = 68/150 (45%), Gaps = 9/150 (6%)

Query: 121 VRRDSEVVLLFFYAPWCGQSIAARAEIEQAASRLSDQVLFVAINCWWNQGKCRKQKHFFY 180
           V  D++++L+ FYAPWCG       E E+AA  LS +   + +       +    K F  
Sbjct: 190 VVNDADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATAETDLAKRFDV 249

Query: 181 --FPVIYLYHRSFGPIEYKGPMSAV-YIEKFVRRVMKPLLYIPSQSELLDFLSNYEPG-V 236
             +P + ++ R   P +Y GP      ++  + +   P   I +  ++ +FL + +   +
Sbjct: 250 SGYPTLKIF-RKGRPYDYNGPREKYGIVDYMIEQSGPPSKEILTLKQVQEFLKDGDDVII 308

Query: 237 LGYFEFSGSPQPPGYLTFFTSALHSLKKDY 266
           +G F+    P    Y      A ++L++DY
Sbjct: 309 IGVFKGESDPAYQQY----QDAANNLREDY 334



 Score = 35.8 bits (81), Expect = 0.20
 Identities = 26/70 (37%), Positives = 34/70 (48%), Gaps = 5/70 (7%)

Query: 673 FWEVVLQKQDVLLLYYAPWCGFCPSLNHIFIQLARNLPMD---TFTVARID-VSQNDLPW 728
           F   V  K  VLL +YAPWCG C      + ++A N+  D      VA+ID  S + L  
Sbjct: 72  FDNFVADKDTVLLEFYAPWCGHCKQFAPEYEKIA-NILKDKDPPIPVAKIDATSASVLAS 130

Query: 729 EFMVDRLPTV 738
            F V   PT+
Sbjct: 131 RFDVSGYPTI 140



 Score = 35.4 bits (80), Expect = 0.26
 Identities = 16/34 (47%), Positives = 20/34 (58%)

Query: 124 DSEVVLLFFYAPWCGQSIAARAEIEQAASRLSDQ 157
           D + VLL FYAPWCG       E E+ A+ L D+
Sbjct: 78  DKDTVLLEFYAPWCGHCKQFAPEYEKIANILKDK 111


>gi|239745099 PREDICTED: similar to Golgin subfamily A member 8-like
           protein 1 isoform 1 [Homo sapiens]
          Length = 632

 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 49/162 (30%), Positives = 80/162 (49%), Gaps = 15/162 (9%)

Query: 784 PTKECLQSEAVLQRGHI-SHLEREIQKLRAEISSLQRAQVQVESQLSSARRDEHRLRQQQ 842
           P    + SE  LQ  H+   LER   +L+A++ + QR  +  + Q    R  E RLR+Q+
Sbjct: 297 PEPPAVPSEVELQ--HLRKELERVAGELQAQVKNNQRISLLNQRQEERIREQEERLRKQE 354

Query: 843 RALEEQHSLLHAHSEQLQALYEQ------KTRELQELARKLQEL--ADASENLLTENTWL 894
             ++EQH  L   ++  Q+++E+       T +L++  ++LQE    +  E    +N  L
Sbjct: 355 ERIQEQHKSLQQLAKP-QSVFEEPNNENKSTLQLEQQVKELQEKLGEEHLEAASQQNQQL 413

Query: 895 KILVATMERKLEGRDGAESLAAQREVHPKQPEPSATPQLPGS 936
              ++ M    EG  G E L ++ E  P QP PS  P+ P S
Sbjct: 414 TAQLSLMALPGEGH-GGEHLDSEGEEAP-QPMPS-VPEDPES 452



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 31/104 (29%), Positives = 55/104 (52%), Gaps = 6/104 (5%)

Query: 806 EIQKLRAEISSLQRAQVQVESQLSSARRDEHRLRQQQRALEEQHSLLHAHSEQLQA-LYE 864
           EI +L+  I SL++ + QVE QL   ++  ++ ++ +R LE Q   L+   E+L   LY 
Sbjct: 92  EISQLKNTIKSLKQQKKQVEHQLEEEKKANNKKQKAKRVLEVQLQTLNIQKEELNTDLYH 151

Query: 865 QKTRELQELARKLQELADASENLLTE----NTWLKILVATMERK 904
            K R L+    K ++LA   ++ L       + L  ++AT ++K
Sbjct: 152 MK-RSLRYFEEKSKDLAVRLQHSLQRKGELESVLSDVMATQKKK 194


>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 523

 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 43/169 (25%), Positives = 72/169 (42%), Gaps = 2/169 (1%)

Query: 790 QSEAVLQRGHISHLEREIQKLRAEISSLQRAQVQVESQLSSARRDEHRLRQQQRALEEQH 849
           Q  ++L R     L  + ++LR +   L+  + ++  Q    R  E RLR+Q+  L EQ 
Sbjct: 188 QMLSLLNRRQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQE 247

Query: 850 SLLHAHSEQLQALYEQKTRELQELARKLQELADASENLLTENTWLKILVATM-ERKLEGR 908
             L  H E+L    E+   + + L  + + L +  E L  +   L+     + E++   R
Sbjct: 248 ERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLR 307

Query: 909 DGAESLAAQREVHPKQPEPSATPQ-LPGSSPPPANVSATLVSERNKENR 956
           +  E L  Q E   +Q E     + LPG       V   L  ER +E +
Sbjct: 308 EQEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQ 356



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 40/155 (25%), Positives = 66/155 (42%), Gaps = 17/155 (10%)

Query: 776 SPQNVANSPTKECLQSEAVLQRGHISHLEREIQ----KLRAEISSLQRAQVQVESQLSSA 831
           +P+  A     E LQ E        +HL +E++    +L+AE+ + Q   +    Q    
Sbjct: 149 APEPPAGPSKVEQLQDET-------NHLRKELESVGRQLQAEVENNQMLSLLNRRQEERL 201

Query: 832 RRDEHRLRQQQRALEEQHSLLHAHSEQLQALYEQKTRELQELARKLQELADASENLLTEN 891
           R  E RLR+Q+  L EQ   L    E+L+   E+   + + L  + + L +  E L  + 
Sbjct: 202 REQEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEERLREHEERLCEQE 261

Query: 892 TWLKILVATMERKLEGRDGAESLAAQREVHPKQPE 926
             L       E++   R+  E L  Q E   +Q E
Sbjct: 262 ERL------CEQEERLREQEERLHEQEERLCEQEE 290



 Score = 35.0 bits (79), Expect = 0.34
 Identities = 38/101 (37%), Positives = 52/101 (51%), Gaps = 16/101 (15%)

Query: 818 QRAQVQVESQLSSARRDEH--RLRQQQRALEEQHSLLHAH--SEQLQALYEQKTRELQEL 873
           +R   +VE  L   RR E   RL +++R LEE   LL      +Q + L++Q+T  LQEL
Sbjct: 337 ERLLEEVEKLLEQERRQEEQERLLERERLLEEVEELLEQERLRQQDERLWQQET--LQEL 394

Query: 874 ARKLQELADASENLLTENTWLKILVATMERKLEGRDGAESL 914
            R L+EL    E +L E  W     A  E++ E R G E L
Sbjct: 395 ER-LREL----ERML-ELGW----EALYEQRAEPRSGFEEL 425


>gi|28372543 protein disulfide isomerase-like, testis expressed
           [Homo sapiens]
          Length = 584

 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 36/134 (26%), Positives = 65/134 (48%), Gaps = 6/134 (4%)

Query: 611 IVDVKEESHYILDPKQALMKLTLESFIQNFSVLYSPLKRHLIGSGSAQFPSQHLITEVTT 670
           I+++  ++ Y + P   +   +L+ F ++F  L     +H       ++  Q L+ ++  
Sbjct: 338 ILNLSSDARYKM-PSDDITYESLKKFGRSF--LSKNATKHQSSEEIPKYWDQGLVKQLVG 394

Query: 671 DTFWEVVLQKQ-DVLLLYYAPWCGFCPSLNHIFIQLARNLP-MDTFTVARIDVSQNDLPW 728
             F  VV  K+ DV +++YAPW   C  L  +  +L R      T  +A+IDV+ ND+  
Sbjct: 395 KNFNVVVFDKEKDVFVMFYAPWSKKCKMLFPLLEELGRKYQNHSTIIIAKIDVTANDIQL 454

Query: 729 EFMVDRLPTVLFFP 742
            ++ DR P    FP
Sbjct: 455 MYL-DRYPFFRLFP 467


>gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo
           sapiens]
          Length = 479

 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 40/116 (34%), Positives = 54/116 (46%), Gaps = 10/116 (8%)

Query: 785 TKECLQSEAVLQRGHISHLEREIQKLRAEISSLQR---AQVQVESQLSSA-RRDEHRLRQ 840
           T E L  E       +  L+ E   LR E+ S+ R   A+V+    LS   RR E RLR+
Sbjct: 144 TAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLRE 203

Query: 841 QQRALEEQHSLLHAHSEQL----QALYEQ--KTRELQELARKLQELADASENLLTE 890
           Q+  L EQ   LH   E+L    + L EQ  + RE +E  R+ +E     E  L E
Sbjct: 204 QEERLHEQEERLHEQEERLCEQEERLCEQEERLREQEERLREQEERLHEQEERLCE 259



 Score = 37.0 bits (84), Expect = 0.088
 Identities = 30/102 (29%), Positives = 45/102 (44%), Gaps = 4/102 (3%)

Query: 790 QSEAVLQRGHISHLEREIQKLRAEISSLQRAQVQVESQLSSARRDEHRLRQQQRALEEQH 849
           Q  ++L R     L  + ++L  +   L   + ++  Q       E RLR+Q+  L EQ 
Sbjct: 188 QMLSLLNRRQEERLREQEERLHEQEERLHEQEERLCEQEERLCEQEERLREQEERLREQE 247

Query: 850 SLLHAHSEQLQALYEQKTRELQELARKL-QELADASENLLTE 890
             LH   EQ + L EQ+ R  ++  R   QE     E LL E
Sbjct: 248 ERLH---EQEERLCEQEERLCEQEERLCEQEKLPGQERLLEE 286


>gi|239745111 PREDICTED: Golgin subfamily A member 8-like protein 3
           isoform 1 [Homo sapiens]
          Length = 632

 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 53/166 (31%), Positives = 78/166 (46%), Gaps = 23/166 (13%)

Query: 784 PTKECLQSEAVLQRGHI-SHLEREIQKLRAEISSLQRAQVQVESQLSSARRDEHRLRQQQ 842
           P    + SE  LQ  H+   LER   +L+A++ + QR  +  + Q    R  E RLR+Q+
Sbjct: 297 PEPPAVPSEVELQ--HLRKELERVAGELQAQVKNNQRISLLNQRQEERIREQEERLRKQE 354

Query: 843 RALEEQHSLL-----------HAHSEQLQAL-YEQKTRELQELARKLQELADASENLLTE 890
             ++EQH  L             ++E   AL  EQ+ +ELQE   KL E  +  E    +
Sbjct: 355 ERIQEQHKSLQQLAKPQSVFKEPNNENKNALQLEQQVKELQE---KLGE--EHLEAASQQ 409

Query: 891 NTWLKILVATMERKLEGRDGAESLAAQREVHPKQPEPSATPQLPGS 936
           N  L   ++ M    EG  G E L ++ E  P+ P PS  P+ P S
Sbjct: 410 NQQLTAQLSLMALPGEGH-GGEHLDSEGEEAPR-PMPS-VPEDPES 452



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 31/104 (29%), Positives = 55/104 (52%), Gaps = 6/104 (5%)

Query: 806 EIQKLRAEISSLQRAQVQVESQLSSARRDEHRLRQQQRALEEQHSLLHAHSEQLQA-LYE 864
           EI +L+  I SL++ + QVE QL   ++  ++ ++ +R LE Q   L+   E+L   LY 
Sbjct: 92  EISQLKNTIKSLKQQKKQVEHQLEEEKKANNKKQKAKRVLEVQIQTLNIQKEELNTDLYH 151

Query: 865 QKTRELQELARKLQELADASENLLTE----NTWLKILVATMERK 904
            K R L+    K ++LA   ++ L       + L  ++AT ++K
Sbjct: 152 MK-RSLRYFEEKSKDLAVRLQHSLQRKGELESVLSNVMATQKKK 194


>gi|229577185 epidermal growth factor receptor pathway substrate 15
           isoform B [Homo sapiens]
          Length = 582

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 45/165 (27%), Positives = 70/165 (42%), Gaps = 26/165 (15%)

Query: 807 IQKLRAEISSLQRAQVQVESQLSSARRDEHRLRQQQRALEEQHSLLHAHSEQLQALYEQK 866
           I  L+AE++S +      E +L+ AR +  RL+Q+   LEE      A  E LQ   +  
Sbjct: 112 ISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESGKAQLEPLQQHLQDS 171

Query: 867 TRELQELARKLQELADASENLLTENTWL----KILV----------------ATMERKLE 906
            +E+  +  KL E+ D  EN  ++  W      ILV                A +   +E
Sbjct: 172 QQEISSMQMKLMEMKDL-ENHNSQLNWCSSPHSILVNGATDYCSLSTSSSETANLNEHVE 230

Query: 907 GRDGAESLAAQREVHPKQPEPSATPQLPGSSPPPANVSATLVSER 951
           G+   ES      +H + P  S +P+L  S     N   T V+E+
Sbjct: 231 GQSNLES----EPIHQESPARS-SPELLPSGVTDENEVTTAVTEK 270



 Score = 33.1 bits (74), Expect = 1.3
 Identities = 28/126 (22%), Positives = 55/126 (43%), Gaps = 14/126 (11%)

Query: 774 ASSPQNVANSPTKECLQSEAVLQR-GHISHLEREIQKLRAEISSLQRAQVQVESQLSSAR 832
           +S  +N      KE  + + + QR   +  L+ E+Q+    +  LQ  + QV+  L    
Sbjct: 31  SSREKNNVEQDLKE--KEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELD 88

Query: 833 RDEHRLRQQ-----QRALEEQHSL------LHAHSEQLQALYEQKTRELQELARKLQELA 881
             + +L +Q     ++  EE   +      L +   Q+    E+  +  +EL+R  QE A
Sbjct: 89  EQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETA 148

Query: 882 DASENL 887
           +  E++
Sbjct: 149 ELEESV 154


>gi|4503593 epidermal growth factor receptor pathway substrate 15
           isoform A [Homo sapiens]
          Length = 896

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 45/165 (27%), Positives = 70/165 (42%), Gaps = 26/165 (15%)

Query: 807 IQKLRAEISSLQRAQVQVESQLSSARRDEHRLRQQQRALEEQHSLLHAHSEQLQALYEQK 866
           I  L+AE++S +      E +L+ AR +  RL+Q+   LEE      A  E LQ   +  
Sbjct: 426 ISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESGKAQLEPLQQHLQDS 485

Query: 867 TRELQELARKLQELADASENLLTENTWL----KILV----------------ATMERKLE 906
            +E+  +  KL E+ D  EN  ++  W      ILV                A +   +E
Sbjct: 486 QQEISSMQMKLMEMKDL-ENHNSQLNWCSSPHSILVNGATDYCSLSTSSSETANLNEHVE 544

Query: 907 GRDGAESLAAQREVHPKQPEPSATPQLPGSSPPPANVSATLVSER 951
           G+   ES      +H + P  S +P+L  S     N   T V+E+
Sbjct: 545 GQSNLES----EPIHQESPARS-SPELLPSGVTDENEVTTAVTEK 584



 Score = 32.3 bits (72), Expect = 2.2
 Identities = 24/110 (21%), Positives = 49/110 (44%), Gaps = 12/110 (10%)

Query: 790 QSEAVLQR-GHISHLEREIQKLRAEISSLQRAQVQVESQLSSARRDEHRLRQQ-----QR 843
           + + + QR   +  L+ E+Q+    +  LQ  + QV+  L      + +L +Q     ++
Sbjct: 359 KEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEVRKK 418

Query: 844 ALEEQHSL------LHAHSEQLQALYEQKTRELQELARKLQELADASENL 887
             EE   +      L +   Q+    E+  +  +EL+R  QE A+  E++
Sbjct: 419 CAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESV 468


>gi|113425145 PREDICTED: similar to Golgin subfamily A member 8-like
           protein 2 isoform 3 [Homo sapiens]
          Length = 632

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 46/159 (28%), Positives = 75/159 (47%), Gaps = 14/159 (8%)

Query: 784 PTKECLQSEAVLQRGHI-SHLEREIQKLRAEISSLQRAQVQVESQLSSARRDEHRLRQQQ 842
           P    + SE  LQ  H+   LER   +L++++ + Q   +    Q    R  E RLR+Q+
Sbjct: 297 PEPPAVPSEVELQ--HLRKELERVAGELQSQVKNNQHISLLNRRQEERIREQEERLRKQE 354

Query: 843 RALEEQHSLLHAHSEQLQALYEQ------KTRELQELARKLQEL--ADASENLLTENTWL 894
             L+EQH  L   ++  Q+++E+       T +L++  ++LQE    +  E    +N  L
Sbjct: 355 ERLQEQHEKLRQLAKP-QSVFEELNNENKSTLQLEQQVKELQEKLGEEHLEAASQQNQQL 413

Query: 895 KILVATMERKLEGRDGAESLAAQREVHPKQPEPSATPQL 933
              ++ M    EG  G E L ++ E  P QP PS    L
Sbjct: 414 TAQLSLMALPGEGH-GGEHLDSEGEEAP-QPMPSVPEDL 450



 Score = 35.0 bits (79), Expect = 0.34
 Identities = 29/106 (27%), Positives = 51/106 (48%), Gaps = 10/106 (9%)

Query: 806 EIQKLRAEISSLQRAQVQVESQLSSARRDEHRLRQQQRALEEQHSLLHAHSEQLQA-LYE 864
           +I +L+  I SL++ + QVE QL   ++  +  ++ +R LE Q   L    E+L   LY 
Sbjct: 92  KISRLKNTIKSLKQQKKQVEHQLEEEKKANNERQKAERELEVQIQTLIIQKEELNTDLYH 151

Query: 865 QK------TRELQELARKLQELADASENLLTENTWLKILVATMERK 904
            +        E ++LA +LQ        L    + L  ++AT ++K
Sbjct: 152 MERSLRYFEEESKDLAVRLQHSLQCKGEL---ESALSAVIATEKKK 194


>gi|239745130 PREDICTED: similar to Golgin subfamily A member 8-like
           protein 1 isoform 1 [Homo sapiens]
          Length = 632

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 46/162 (28%), Positives = 76/162 (46%), Gaps = 15/162 (9%)

Query: 784 PTKECLQSEAVLQRGHI-SHLEREIQKLRAEISSLQRAQVQVESQLSSARRDEHRLRQQQ 842
           P    + SE  LQ  H+   LER   +L+A++   QR  +  + Q    +  E RLR+Q+
Sbjct: 297 PEPPAVPSEVELQ--HLRKELERVAGELQAQVKKNQRISLLNQRQEERIQEQEERLRKQE 354

Query: 843 RALEEQHSLLHAHSEQLQALYEQKTRELQELARKLQELADASENLLTE--------NTWL 894
             ++EQH  L   ++  Q+++E+   E +   +  Q++ +  E L  E        N  L
Sbjct: 355 ERIQEQHKSLQQLAKP-QSVFEEPNNENKNALQLEQQVKELQEKLGEEHLEAASQQNQQL 413

Query: 895 KILVATMERKLEGRDGAESLAAQREVHPKQPEPSATPQLPGS 936
              ++ M    EG  G E L ++ E  P+ P PS  P+ P S
Sbjct: 414 TAQLSLMALPGEGH-GGEHLDSEGEEAPR-PMPS-VPEDPES 452


>gi|24308127 DnaJ (Hsp40) homolog, subfamily C, member 10 [Homo
           sapiens]
          Length = 793

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 28/92 (30%), Positives = 49/92 (53%), Gaps = 2/92 (2%)

Query: 124 DSEVVLLFFYAPWCGQSIAARAEIEQAASRLSDQVLFVAINCWWNQGKCRKQKHFFYFPV 183
           D E  L+ F+APWC    A   E+ +A++ L  Q+ F  ++C  ++G C    +   +P 
Sbjct: 467 DKEPWLVDFFAPWCPPCRALLPELRRASNLLYGQLKFGTLDCTVHEGLC-NMYNIQAYPT 525

Query: 184 IYLYHRSFGPIEYKGPMSAVYIEKFVRRVMKP 215
             ++++S    EY+G  SA  I +F+  +M P
Sbjct: 526 TVVFNQS-NIHEYEGHHSAEQILEFIEDLMNP 556



 Score = 36.6 bits (83), Expect = 0.12
 Identities = 20/43 (46%), Positives = 26/43 (60%), Gaps = 1/43 (2%)

Query: 666 TEVTTDTFWEVVLQ-KQDVLLLYYAPWCGFCPSLNHIFIQLAR 707
           T++T  TF E VLQ K   ++ +YAPWCG C +    F  LAR
Sbjct: 673 TDLTPQTFSEKVLQGKNHWVIDFYAPWCGPCQNFAPEFELLAR 715



 Score = 34.7 bits (78), Expect = 0.44
 Identities = 26/82 (31%), Positives = 42/82 (51%), Gaps = 5/82 (6%)

Query: 665 ITEVTTDTFWEVVLQKQ--DVLLL-YYAPWCGFCPSLNHIFIQLARNLPMDTFTVARIDV 721
           +  +T  TF E+V Q++  +V ++ +Y+PWC  C  L   + ++AR L      V  ID 
Sbjct: 558 VVSLTPTTFNELVTQRKHNEVWMVDFYSPWCHPCQVLMPEWKRMARTL-TGLINVGSIDC 616

Query: 722 SQ-NDLPWEFMVDRLPTVLFFP 742
            Q +    +  V R P + FFP
Sbjct: 617 QQYHSFCAQENVQRYPEIRFFP 638



 Score = 31.2 bits (69), Expect = 4.8
 Identities = 21/75 (28%), Positives = 32/75 (42%), Gaps = 1/75 (1%)

Query: 117 YAEYVRRDSEVVLLFFYAPWCGQSIAARAEIEQAASRLSDQVLFVAINCWWNQGKCRKQK 176
           ++E V +     ++ FYAPWCG       E E  A  +  +V    ++C      C+K  
Sbjct: 680 FSEKVLQGKNHWVIDFYAPWCGPCQNFAPEFELLARMIKGKVKAGKVDCQAYAQTCQKAG 739

Query: 177 HFFYFPV-IYLYHRS 190
              Y  V  Y Y R+
Sbjct: 740 IRAYPTVKFYFYERA 754



 Score = 30.4 bits (67), Expect = 8.3
 Identities = 18/83 (21%), Positives = 34/83 (40%), Gaps = 1/83 (1%)

Query: 126 EVVLLFFYAPWCGQSIAARAEIEQAASRLSDQVLFVAINCWWNQGKCRKQKHFFYFPVIY 185
           E+  + FY+P C             A  +   +   A+NC  ++  CR  K    +P ++
Sbjct: 147 ELWFVNFYSPGCSHCHDLAPTWRDFAKEVDGLLRIGAVNCGDDRMLCR-MKGVNSYPSLF 205

Query: 186 LYHRSFGPIEYKGPMSAVYIEKF 208
           ++     P++Y G  S   +  F
Sbjct: 206 IFRSGMAPVKYHGDRSKESLVSF 228


>gi|113425119 PREDICTED: similar to golgi autoantigen, golgin
           subfamily a, 8E isoform 2 [Homo sapiens]
          Length = 631

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 48/162 (29%), Positives = 78/162 (48%), Gaps = 15/162 (9%)

Query: 784 PTKECLQSEAVLQRGHI-SHLEREIQKLRAEISSLQRAQVQVESQLSSARRDEHRLRQQQ 842
           P    + SE  LQ  H+   LER   +L++++ + Q   +    Q    R  E RLR+Q+
Sbjct: 296 PEPPAVPSEVELQ--HLRKELERVAGELQSQVKNNQHISLLNRRQEERIREQEERLRKQE 353

Query: 843 RALEEQHSLLHAHSEQLQALYEQ------KTRELQELARKLQEL--ADASENLLTENTWL 894
             L+EQH  L   ++  Q+++E+       T +L++  ++LQE    +  E    +N  L
Sbjct: 354 ERLQEQHEKLRQLAKP-QSVFEELNNENKSTLQLEQQVKELQEKLGEEHLEVASQQNQQL 412

Query: 895 KILVATMERKLEGRDGAESLAAQREVHPKQPEPSATPQLPGS 936
              ++ M    EG  G E L ++ E  P QP PS  P+ P S
Sbjct: 413 TAQLSLMALPGEGH-GGEHLDSEGEEAP-QPMPS-VPEDPES 451



 Score = 35.0 bits (79), Expect = 0.34
 Identities = 21/76 (27%), Positives = 38/76 (50%)

Query: 806 EIQKLRAEISSLQRAQVQVESQLSSARRDEHRLRQQQRALEEQHSLLHAHSEQLQALYEQ 865
           +I +L+  I SL++ + QVE QL   ++  +  ++ +R LE Q   L    E+L      
Sbjct: 92  KISRLKNTIKSLKQQKKQVEHQLEEEKKANNERQKAERVLEVQIQTLIIQKEELNTDLYH 151

Query: 866 KTRELQELARKLQELA 881
             R L+    + ++LA
Sbjct: 152 MERSLRYFEEESKDLA 167


>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
          Length = 2115

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 45/169 (26%), Positives = 80/169 (47%), Gaps = 11/169 (6%)

Query: 768  LHHSDPASSPQNVANSPTKECLQSEAVLQRGHISHLEREIQKLRAEISSLQRAQVQVESQ 827
            L  SD AS  Q        + +Q++    +     L+ ++ +L+A++S  ++A    + Q
Sbjct: 1558 LADSDQASKVQQ----QKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQ 1613

Query: 828  LSSARRDEHRLRQQQRALEEQ-HSL--LHAHSEQLQALYEQKTRELQELARKLQELADAS 884
            +  A+      +QQ + L+EQ  SL  L   +++L+A  E+   ELQ+   K +E     
Sbjct: 1614 MEKAKTHYDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTC 1673

Query: 885  ENLLTENTWLKILVATMERKLEGRDGAESLAAQREVHPKQPEPSATPQL 933
             +L  +   L+  VA  +++L  RD  +   A   +  K  EP A PQL
Sbjct: 1674 RHLTAQVRSLEAQVAHADQQL--RDLGKFQVATDAL--KSREPQAKPQL 1718



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 35/135 (25%), Positives = 64/135 (47%), Gaps = 5/135 (3%)

Query: 799 HISHLEREIQKLRAEISSLQRA----QVQVESQLSSARRDEHRLRQQQRALEEQHSLLHA 854
           H+  L+  + +L  E S   +     Q Q+E +LS+A +D+  L ++   L+ + S L  
Sbjct: 333 HLQQLQDALNELTEEHSKATQEWLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEE 392

Query: 855 HSEQLQALYEQKTRELQELARKLQELADASENLLTENTWLKILVATMERKLEGRDGAESL 914
           H  QLQ    Q+  E+     +L+ L   +  L   NT L+  V  +E +  G+  A+ L
Sbjct: 393 HLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLETE-RGQQEAKLL 451

Query: 915 AAQREVHPKQPEPSA 929
           A +     ++ + S+
Sbjct: 452 AERGHFEEEKQQLSS 466



 Score = 36.6 bits (83), Expect = 0.12
 Identities = 45/179 (25%), Positives = 79/179 (44%), Gaps = 35/179 (19%)

Query: 771 SDPASSPQNVANSPTKECLQSEAVLQRGHISHLEREIQKLRAEISSLQRAQVQVESQLSS 830
           +D  SS  N+  S  KE L+  +   + H + L  ++  L +E+++L     Q + +L+ 
Sbjct: 469 TDLQSSISNL--SQAKEELEQAS---QAHGARLTAQVASLTSELTTLNATIQQQDQELAG 523

Query: 831 ----ARRDEHRLRQQQRALEEQHSLLHAHSEQLQALYEQKTRELQELARK--------LQ 878
               A+  + +L Q  +  E+    L    EQL +  +QK ++L+E+A K         Q
Sbjct: 524 LKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQ 583

Query: 879 ELADASE----NLLTENTWLKILVATMERKL--------------EGRDGAESLAAQRE 919
           +LA A+E    +L   +  LK L A  + K               E RD A++   Q +
Sbjct: 584 QLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQ 642



 Score = 36.2 bits (82), Expect = 0.15
 Identities = 20/93 (21%), Positives = 49/93 (52%), Gaps = 11/93 (11%)

Query: 804  EREIQKLRAEISSLQRAQVQVESQLSSARRD-----------EHRLRQQQRALEEQHSLL 852
            E+ +Q+L A  +  +    +V+ +  S  R+           + ++ ++++  +E+   L
Sbjct: 1474 EKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQEERQKL 1533

Query: 853  HAHSEQLQALYEQKTRELQELARKLQELADASE 885
             A  EQL+    ++T++++EL++KL +   AS+
Sbjct: 1534 TAQVEQLEVFQREQTKQVEELSKKLADSDQASK 1566



 Score = 35.4 bits (80), Expect = 0.26
 Identities = 27/90 (30%), Positives = 44/90 (48%), Gaps = 4/90 (4%)

Query: 807  IQKLRAEISSLQRAQVQVESQLSSARRDEHRLRQQQRALEEQHSLLHAHSEQLQALYEQK 866
            I  L  E+S L R  ++ E +    +R      ++ + LEE+  LL A +    A   ++
Sbjct: 1227 ISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQAETASNSARAAER 1286

Query: 867  TRELQELARKLQELAD----ASENLLTENT 892
            +  L+E  + L+E A+    ASENL  E T
Sbjct: 1287 SSALREEVQSLREEAEKQRVASENLRQELT 1316



 Score = 34.7 bits (78), Expect = 0.44
 Identities = 30/137 (21%), Positives = 52/137 (37%), Gaps = 7/137 (5%)

Query: 769 HHSDPASSPQNVANSPTKECLQSEAVLQRGHISHLEREIQKLRAEISSLQRAQVQVESQL 828
           H  +  SS         KE  + +   ++ H   L    ++  A +     A  Q+E+  
Sbjct: 551 HQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEAL- 609

Query: 829 SSARRDEHRLRQQQRALEEQHSLLHAHSEQLQALYEQKTRELQELARKLQELADASENLL 888
                 E     +   L++Q  + +   +  Q    Q  RE  EL+RK++EL    E   
Sbjct: 610 ------EKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETAR 663

Query: 889 TENTWLKILVATMERKL 905
            E    +  VA +E +L
Sbjct: 664 QEQHEAQAQVAELELQL 680



 Score = 30.8 bits (68), Expect = 6.3
 Identities = 31/96 (32%), Positives = 45/96 (46%), Gaps = 14/96 (14%)

Query: 790  QSEAVLQRGHISHLEREIQKLRAEISSLQRAQVQVESQLSSARRDEHRLRQQQRALEEQH 849
            QSEA    G       +++ LRAE+S L++   Q + Q   A   E  L  ++ +  E+ 
Sbjct: 1108 QSEAA---GRTEPTGPKLEALRAEVSKLEQ---QCQKQQEQADSLERSLEAERASRAERD 1161

Query: 850  SLLHAHSEQLQALYEQKTREL----QELARKLQELA 881
            S L    E LQ   E+K +EL      LA   +ELA
Sbjct: 1162 SAL----ETLQGQLEEKAQELGHSQSALASAQRELA 1193



 Score = 30.4 bits (67), Expect = 8.3
 Identities = 32/142 (22%), Positives = 55/142 (38%), Gaps = 10/142 (7%)

Query: 789  LQSEAVLQRGHISHLEREIQKLRAEI----SSLQRAQVQVESQLSSARRDEHRLRQQQRA 844
            L+ +   Q+     LER ++  RA      S+L+  Q Q+E +       +  L   QR 
Sbjct: 1132 LEQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRE 1191

Query: 845  LEEQHSLLHAHSEQLQALYEQKTRELQELARKLQELADASENLLTENTWLKILVATMERK 904
            L    + +  HS+       Q  R  QE  RK   ++   E +   N         +E++
Sbjct: 1192 LAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNR------QVLEKE 1245

Query: 905  LEGRDGAESLAAQREVHPKQPE 926
             E ++    + A+ E   K  E
Sbjct: 1246 GESKELKRLVMAESEKSQKLEE 1267


>gi|154354987 hook homolog 2 isoform 2 [Homo sapiens]
          Length = 717

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 52/182 (28%), Positives = 86/182 (47%), Gaps = 32/182 (17%)

Query: 800 ISHLEREIQKLRAEISSLQRAQV---QVESQLSSARR---DEHRLRQQQRALEEQHSLLH 853
           ++ L +E Q L+ E+  L+++     Q+E+ L+S RR   +   LR+Q R LEE+++   
Sbjct: 283 LTSLAQEAQALKDEMDELRQSSERAGQLEATLTSCRRRLGELRELRRQVRQLEERNA--- 339

Query: 854 AHSEQ-------------LQALYEQKTRELQELARKLQELADASENLLTENTWL----KI 896
            H+E+             L+A  E + R++QEL  + QE A  +E  L E   L    + 
Sbjct: 340 GHAERTRQLEDELRRAGSLRAQLEAQRRQVQELQGQRQEEAMKAEKWLFECRNLEEKYES 399

Query: 897 LVATMERKLEGRDGAESLAAQREVHPKQPEP----SATPQLPGSSPPPANVSATLVSERN 952
           +    ER L  RD      A  E+   Q +P     A P L  +S P  N++A ++    
Sbjct: 400 VTKEKERLLAERDSLRE--ANEELRCAQLQPRGLTQADPSLDPTSTPVDNLAAEILPAEL 457

Query: 953 KE 954
           +E
Sbjct: 458 RE 459



 Score = 31.2 bits (69), Expect = 4.8
 Identities = 24/100 (24%), Positives = 43/100 (43%), Gaps = 10/100 (10%)

Query: 798 GHISHLEREIQKLRAEISSLQRAQVQVESQLSSARRDEHRLRQQQRALEE-----QHSLL 852
           G +  L R++++L    +       Q+E +L  A     +L  Q+R ++E     Q   +
Sbjct: 322 GELRELRRQVRQLEERNAGHAERTRQLEDELRRAGSLRAQLEAQRRQVQELQGQRQEEAM 381

Query: 853 HAHS-----EQLQALYEQKTRELQELARKLQELADASENL 887
            A         L+  YE  T+E + L  +   L +A+E L
Sbjct: 382 KAEKWLFECRNLEEKYESVTKEKERLLAERDSLREANEEL 421



 Score = 31.2 bits (69), Expect = 4.8
 Identities = 28/108 (25%), Positives = 48/108 (44%), Gaps = 13/108 (12%)

Query: 772 DPASSPQNVANSPTKECLQSEAVLQRGHISHLEREIQKLRAEISSLQRAQVQVESQLSSA 831
           DP S+P    ++   E L +E    R  +  L+ E ++L  + ++ +  Q +++  L  A
Sbjct: 439 DPTSTP---VDNLAAEILPAEL---RETLLRLQLENKRLCRQEAADRERQEELQRHLEDA 492

Query: 832 RRDEHRLRQQQRALEEQHSLLHAHSEQLQALYEQKTRELQELARKLQE 879
            R  H        LE QH L      +L+A  E   + LQE   K ++
Sbjct: 493 NRARH-------GLETQHRLNQQQLSELRAQVEDLQKALQEQGGKTED 533


>gi|154354985 hook homolog 2 isoform 1 [Homo sapiens]
          Length = 719

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 52/182 (28%), Positives = 86/182 (47%), Gaps = 32/182 (17%)

Query: 800 ISHLEREIQKLRAEISSLQRAQV---QVESQLSSARR---DEHRLRQQQRALEEQHSLLH 853
           ++ L +E Q L+ E+  L+++     Q+E+ L+S RR   +   LR+Q R LEE+++   
Sbjct: 283 LTSLAQEAQALKDEMDELRQSSERAGQLEATLTSCRRRLGELRELRRQVRQLEERNA--- 339

Query: 854 AHSEQ-------------LQALYEQKTRELQELARKLQELADASENLLTENTWL----KI 896
            H+E+             L+A  E + R++QEL  + QE A  +E  L E   L    + 
Sbjct: 340 GHAERTRQLEDELRRAGSLRAQLEAQRRQVQELQGQRQEEAMKAEKWLFECRNLEEKYES 399

Query: 897 LVATMERKLEGRDGAESLAAQREVHPKQPEP----SATPQLPGSSPPPANVSATLVSERN 952
           +    ER L  RD      A  E+   Q +P     A P L  +S P  N++A ++    
Sbjct: 400 VTKEKERLLAERDSLRE--ANEELRCAQLQPRGLTQADPSLDPTSTPVDNLAAEILPAEL 457

Query: 953 KE 954
           +E
Sbjct: 458 RE 459



 Score = 31.2 bits (69), Expect = 4.8
 Identities = 24/100 (24%), Positives = 43/100 (43%), Gaps = 10/100 (10%)

Query: 798 GHISHLEREIQKLRAEISSLQRAQVQVESQLSSARRDEHRLRQQQRALEE-----QHSLL 852
           G +  L R++++L    +       Q+E +L  A     +L  Q+R ++E     Q   +
Sbjct: 322 GELRELRRQVRQLEERNAGHAERTRQLEDELRRAGSLRAQLEAQRRQVQELQGQRQEEAM 381

Query: 853 HAHS-----EQLQALYEQKTRELQELARKLQELADASENL 887
            A         L+  YE  T+E + L  +   L +A+E L
Sbjct: 382 KAEKWLFECRNLEEKYESVTKEKERLLAERDSLREANEEL 421



 Score = 31.2 bits (69), Expect = 4.8
 Identities = 28/108 (25%), Positives = 48/108 (44%), Gaps = 13/108 (12%)

Query: 772 DPASSPQNVANSPTKECLQSEAVLQRGHISHLEREIQKLRAEISSLQRAQVQVESQLSSA 831
           DP S+P    ++   E L +E    R  +  L+ E ++L  + ++ +  Q +++  L  A
Sbjct: 439 DPTSTP---VDNLAAEILPAEL---RETLLRLQLENKRLCRQEAADRERQEELQRHLEDA 492

Query: 832 RRDEHRLRQQQRALEEQHSLLHAHSEQLQALYEQKTRELQELARKLQE 879
            R  H        LE QH L      +L+A  E   + LQE   K ++
Sbjct: 493 NRARH-------GLETQHRLNQQQLSELRAQVEDLQKALQEQGGKTED 533


>gi|239745147 PREDICTED: similar to Golgin subfamily A member 8-like
           protein 1 isoform 1 [Homo sapiens]
          Length = 630

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 45/158 (28%), Positives = 74/158 (46%), Gaps = 13/158 (8%)

Query: 784 PTKECLQSEAVLQRGHI-SHLEREIQKLRAEISSLQRAQVQVESQLSSARRDEHRLRQQQ 842
           P    + SE  LQ  H+   LER   +L+A++   QR  +  + Q    +  E RLR+Q+
Sbjct: 297 PEPPAVPSEVELQ--HLRKELERVAGELQAQVKKNQRISLLNQRQEERIQEQEERLRKQE 354

Query: 843 RALEEQHSLLHAHSEQLQALYEQKTRE------LQELARKLQELADASENLLTENTWLKI 896
             ++EQH  L   ++  Q+++E+   E      L++  ++LQE     E+L   +   + 
Sbjct: 355 ERIQEQHKSLQQLAKP-QSVFEEPNNENKNALQLEQQVKELQEKL-GEEHLEAASQQNQQ 412

Query: 897 LVATME-RKLEGRDGAESLAAQREVHPKQPEPSATPQL 933
           L A +    L G    E L ++ E  P QP PS    L
Sbjct: 413 LTAQLSLMALPGEGHGEHLDSEGEEAP-QPMPSVPEDL 449



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 31/104 (29%), Positives = 55/104 (52%), Gaps = 6/104 (5%)

Query: 806 EIQKLRAEISSLQRAQVQVESQLSSARRDEHRLRQQQRALEEQHSLLHAHSEQLQA-LYE 864
           EI +L+  I SL++ + QVE QL   ++  ++ ++ +R LE Q   L+   E+L   LY 
Sbjct: 92  EISQLKNTIKSLKQQKKQVEHQLEEEKKANNKKQKAKRVLEVQIQTLNIQKEELNTDLYH 151

Query: 865 QKTRELQELARKLQELADASENLLTE----NTWLKILVATMERK 904
            K R L+    K ++LA   ++ L       + L  ++AT ++K
Sbjct: 152 MK-RSLRYFEEKSKDLAVRLQHSLQRKGELESVLSNVMATQKKK 194


>gi|34577114 cytomatrix protein p110 [Homo sapiens]
          Length = 957

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 28/119 (23%), Positives = 59/119 (49%)

Query: 787 ECLQSEAVLQRGHISHLEREIQKLRAEISSLQRAQVQVESQLSSARRDEHRLRQQQRALE 846
           E  +S +   +  I  L++E+ K  +E+ +LQ     + +Q S  ++    L++   A E
Sbjct: 423 EVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKE 482

Query: 847 EQHSLLHAHSEQLQALYEQKTRELQELARKLQELADASENLLTENTWLKILVATMERKL 905
           ++ ++L    + L+   E+K   L +  ++LQ+L +    L  E   +K ++   ERK+
Sbjct: 483 QRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKI 541



 Score = 31.2 bits (69), Expect = 4.8
 Identities = 35/160 (21%), Positives = 66/160 (41%), Gaps = 34/160 (21%)

Query: 786 KECLQSEAVLQRGH---------------ISHLEREIQKLRAEISSLQRAQVQVESQLSS 830
           +EC + EA L++ H               I  L++E    R E     +AQ +V+  L  
Sbjct: 676 EECSKLEAQLKKAHNIEDDSRMNPEFADQIKQLDKEASYYRDECG---KAQAEVDRLLEI 732

Query: 831 ARRDEHRLRQQQRALEEQHSLLHAHSEQL----------QALYEQKTREL-QELARKLQE 879
            +  E+    + + + E  SL   H +            Q L ++K  +L +E+ R+   
Sbjct: 733 LKEVENEKNDKDKKIAELESLTLRHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDS 792

Query: 880 LADASENLLTENTWLKILVATMERKLEGRDGAESLAAQRE 919
           +AD S++L  E      L+  +E+  +  D  ++  A  +
Sbjct: 793 MADNSQHLQIEE-----LMNALEKTRQELDATKARLASTQ 827


>gi|31542661 transmembrane protein 57 [Homo sapiens]
          Length = 664

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 33/149 (22%), Positives = 73/149 (48%), Gaps = 16/149 (10%)

Query: 771 SDPASSPQN------VANSPT------KECLQSEAVLQRGHISHLEREIQKLRAEISSLQ 818
           S P+SS +N       + SP+      + C+ +  + +   +  LE++I+KL+A++ + +
Sbjct: 342 SIPSSSSKNEKKQKCTSKSPSTHKDLMENCIPNNQLSKPDALVRLEQDIKKLKADLQASR 401

Query: 819 RAQVQVESQLSSARRDEHRLRQQQRALEEQHSLLHAHSEQLQALYEQKTRELQELARKLQ 878
           + + ++ SQ+SS    E  +R +   L +++ LL         + ++  + + +L +KL+
Sbjct: 402 QVEQELRSQISSLSSTERGIRSEMGQLRQENELLQNKLHNAVQMKQKDKQNISQLEKKLK 461

Query: 879 ELADA----SENLLTENTWLKILVATMER 903
              +A     + L+ E    K+  AT  R
Sbjct: 462 AEQEARSFVEKQLMEEKKRKKLEEATAAR 490


>gi|20070125 prolyl 4-hydroxylase, beta subunit precursor [Homo
           sapiens]
          Length = 508

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 33/144 (22%), Positives = 63/144 (43%), Gaps = 5/144 (3%)

Query: 611 IVDVKEESHYILDPKQALMKLTLESFIQNFSVLYSPLKRHLIGSGSAQFPSQHLITEVTT 670
           ++ ++EE        + L    +  F   F  L   +K HL+     +   +  +  +  
Sbjct: 317 LITLEEEMTKYKPESEELTAERITEFCHRF--LEGKIKPHLMSQELPEDWDKQPVKVLVG 374

Query: 671 DTFWEVVL-QKQDVLLLYYAPWCGFCPSLNHIFIQLARNL-PMDTFTVARIDVSQNDLPW 728
             F +V   +K++V + +YAPWCG C  L  I+ +L       +   +A++D + N++  
Sbjct: 375 KNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANEVE- 433

Query: 729 EFMVDRLPTVLFFPCNRKDLSVKY 752
              V   PT+ FFP +     + Y
Sbjct: 434 AVKVHSFPTLKFFPASADRTVIDY 457



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 22/72 (30%), Positives = 40/72 (55%), Gaps = 3/72 (4%)

Query: 673 FWEVVLQKQDVLLLYYAPWCGFCPSLNHIFIQLARNLPMD--TFTVARIDVS-QNDLPWE 729
           F E +   + +L+ +YAPWCG C +L   + + A  L  +     +A++D + ++DL  +
Sbjct: 34  FAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQ 93

Query: 730 FMVDRLPTVLFF 741
           + V   PT+ FF
Sbjct: 94  YGVRGYPTIKFF 105



 Score = 36.2 bits (82), Expect = 0.15
 Identities = 43/203 (21%), Positives = 77/203 (37%), Gaps = 19/203 (9%)

Query: 128 VLLFFYAPWCGQSIAARAEIEQAASRL---SDQVLFVAINCWWNQGKCRKQKHFFYFPVI 184
           +L+ FYAPWCG   A   E  +AA +L     ++    ++    +    +Q     +P I
Sbjct: 44  LLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDA-TEESDLAQQYGVRGYPTI 102

Query: 185 YLYHR--SFGPIEYKGPMSAVYIEKFVRRVMKP-LLYIPSQSELLDFLSNYEPGVLGYFE 241
             +    +  P EY     A  I  ++++   P    +P  +     + + E  V+G+F+
Sbjct: 103 KFFRNGDTASPKEYTAGREADDIVNWLKKRTGPAATTLPDGAAAESLVESSEVAVIGFFK 162

Query: 242 FSGSPQPPGYLTFFTSALHSLKKDYLGTVRFGVITNKHLAKLVSLVHSGSVYLHRHFNTS 301
              S     +L            + +  + FG+ +N  +     L   G V   +     
Sbjct: 163 DVESDSAKQFLQ---------AAEAIDDIPFGITSNSDVFSKYQLDKDGVVLFKKFDEGR 213

Query: 302 LVFPREVLNYTAENICKWALENQ 324
             F  EV   T EN+  +   NQ
Sbjct: 214 NNFEGEV---TKENLLDFIKHNQ 233


>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
            sapiens]
          Length = 1935

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 30/104 (28%), Positives = 54/104 (51%), Gaps = 3/104 (2%)

Query: 791  SEAVLQRGHISHLEREIQKLRAEISSLQRAQVQVESQLSSARRDEHRLRQQQRALEEQHS 850
            +E  +Q  H + +  E QK   ++ SLQ      + QL  A R    L++    +E +++
Sbjct: 1623 NEMEIQLSHANRMAAEAQK---QVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNN 1679

Query: 851  LLHAHSEQLQALYEQKTRELQELARKLQELADASENLLTENTWL 894
            LL A  E+L+A+ EQ  R  +   ++L E ++  + L ++NT L
Sbjct: 1680 LLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSL 1723



 Score = 39.3 bits (90), Expect = 0.018
 Identities = 41/130 (31%), Positives = 64/130 (49%), Gaps = 15/130 (11%)

Query: 786  KECLQSEAVLQRGHISHLEREIQKLRAEISSLQRAQVQVESQLSSARRDEHRLRQQ---- 841
            KE L S+  L RG +++ + +++ L+ ++    +A+  +   L SAR D   LR+Q    
Sbjct: 1294 KEALISQ--LTRGKLTYTQ-QLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEE 1350

Query: 842  -QRALEEQHSLLHAHSE--QLQALYE----QKTRELQELARKL-QELADASENLLTENTW 893
             +   E Q  L  A+SE  Q +  YE    Q+T EL+E  +KL Q L +A E +   N  
Sbjct: 1351 TEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAK 1410

Query: 894  LKILVATMER 903
               L  T  R
Sbjct: 1411 CSSLEKTKHR 1420



 Score = 38.1 bits (87), Expect = 0.040
 Identities = 27/104 (25%), Positives = 55/104 (52%), Gaps = 7/104 (6%)

Query: 803  LEREIQKLRAEISSLQRAQVQVESQLSSARRDEHRLRQQQRALEEQHSLLHAHSEQLQAL 862
            LER  +KL  ++   Q + + +E+       D+ +L ++ +  + + + L+A  E  QAL
Sbjct: 1048 LERAKRKLEGDLKLTQESIMDLEN-------DKQQLDERLKKKDFELNALNARIEDEQAL 1100

Query: 863  YEQKTRELQELARKLQELADASENLLTENTWLKILVATMERKLE 906
              Q  ++L+EL  +++EL +  E   T    ++ L + + R+LE
Sbjct: 1101 GSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELE 1144



 Score = 37.7 bits (86), Expect = 0.052
 Identities = 29/115 (25%), Positives = 51/115 (44%), Gaps = 10/115 (8%)

Query: 803  LEREIQKLRAEISSLQRAQVQVESQLSSARRDEHRLRQQQRALE--------EQHSLLHA 854
            LE E  +L+ +I  L+    +VE +  +       L ++   L+        E+ +L  A
Sbjct: 943  LEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEA 1002

Query: 855  HSEQLQALY--EQKTRELQELARKLQELADASENLLTENTWLKILVATMERKLEG 907
            H + L  L   E K   L +   KL++  D  E  L +   +++ +   +RKLEG
Sbjct: 1003 HQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEG 1057



 Score = 35.0 bits (79), Expect = 0.34
 Identities = 29/128 (22%), Positives = 57/128 (44%), Gaps = 7/128 (5%)

Query: 786  KECLQSEAVLQRGHISHLEREIQKLRAEISS----LQRAQVQVESQLSSARRDEHRLRQQ 841
            K  L+ +  L +  I  LE + Q+L   +      L     ++E + +   + + +L++ 
Sbjct: 1052 KRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKEL 1111

Query: 842  QRALEEQHSLLHAHSE---QLQALYEQKTRELQELARKLQELADASENLLTENTWLKILV 898
            Q  +EE    L A      +++ L    +REL+E++ +L+E   A+   +  N   +   
Sbjct: 1112 QARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEF 1171

Query: 899  ATMERKLE 906
              M R LE
Sbjct: 1172 QKMRRDLE 1179



 Score = 31.6 bits (70), Expect = 3.7
 Identities = 35/147 (23%), Positives = 67/147 (45%), Gaps = 8/147 (5%)

Query: 778  QNVANSPTKECLQSEAVLQRGH-ISHLEREIQKLRAEISSLQRAQVQVESQLSSARRDEH 836
            Q+ A +       +++V + G  I +L+R  QKL  E S  +     V S +    + + 
Sbjct: 1184 QHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKA 1243

Query: 837  RLRQQQRALEEQHSLLHAHSEQLQALYEQKTRELQELARKLQELA---DASENLLTENTW 893
             L +  R LE+Q +   + +E+ Q      T +  +L  +  EL+   D  E L+++ T 
Sbjct: 1244 NLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTR 1303

Query: 894  LKIL----VATMERKLEGRDGAESLAA 916
             K+     +  ++R+LE    A++  A
Sbjct: 1304 GKLTYTQQLEDLKRQLEEEVKAKNALA 1330


>gi|113425137 PREDICTED: similar to Golgin subfamily A member 8-like
           protein 2 isoform 3 [Homo sapiens]
          Length = 632

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 47/162 (29%), Positives = 78/162 (48%), Gaps = 15/162 (9%)

Query: 784 PTKECLQSEAVLQRGHI-SHLEREIQKLRAEISSLQRAQVQVESQLSSARRDEHRLRQQQ 842
           P    + SE  LQ  H+   LER   +L++++ + Q   +    Q    R  E RLR+Q+
Sbjct: 297 PEPPAVPSEVELQ--HLRKELERVAGELQSQVKNNQHISLLNRRQEERIREQEERLRKQE 354

Query: 843 RALEEQHSLLHAHSEQLQALYEQ------KTRELQELARKLQEL--ADASENLLTENTWL 894
             L+EQH  L   ++  Q+++E+       T +L++  ++LQE    +  E    +N  L
Sbjct: 355 ERLQEQHEKLRQLAKP-QSVFEELNNENKSTLQLEQQVKELQEKLGEEHLEAASQQNQQL 413

Query: 895 KILVATMERKLEGRDGAESLAAQREVHPKQPEPSATPQLPGS 936
              ++ M    EG  G E L ++ E  P+ P PS  P+ P S
Sbjct: 414 TAQLSLMALPGEGH-GGEHLDSEGEEAPR-PMPS-VPEDPES 452



 Score = 35.0 bits (79), Expect = 0.34
 Identities = 29/106 (27%), Positives = 51/106 (48%), Gaps = 10/106 (9%)

Query: 806 EIQKLRAEISSLQRAQVQVESQLSSARRDEHRLRQQQRALEEQHSLLHAHSEQLQA-LYE 864
           +I +L+  I SL++ + QVE QL   ++  +  ++ +R LE Q   L    E+L   LY 
Sbjct: 92  KISRLKNTIKSLKQQKKQVEHQLEEEKKANNERQKAERELEVQIQTLIIQKEELNTDLYH 151

Query: 865 QK------TRELQELARKLQELADASENLLTENTWLKILVATMERK 904
            +        E ++LA +LQ        L    + L  ++AT ++K
Sbjct: 152 MERSLRYFEEESKDLAVRLQHSLQCKGEL---ESALSAVIATEKKK 194


>gi|113425121 PREDICTED: similar to Golgin subfamily A member 8-like
           protein 2 isoform 4 [Homo sapiens]
          Length = 632

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 46/159 (28%), Positives = 74/159 (46%), Gaps = 14/159 (8%)

Query: 784 PTKECLQSEAVLQRGHI-SHLEREIQKLRAEISSLQRAQVQVESQLSSARRDEHRLRQQQ 842
           P    + SE  LQ  H+   LER   +L++++ + Q   +    Q    R  E RLR+Q+
Sbjct: 297 PEPPAVPSEVELQ--HLRKELERVAGELQSQVKNNQHISLLNRRQEERIREQEERLRKQE 354

Query: 843 RALEEQHSLLHAHSEQLQALYEQ------KTRELQELARKLQEL--ADASENLLTENTWL 894
             L+EQH  L   ++  Q+++E+       T +L++  ++LQE    +  E    +N  L
Sbjct: 355 ERLQEQHEKLRQLAKP-QSVFEELNNENKSTLQLEQQVKELQEKLGEEHLEAASQQNQQL 413

Query: 895 KILVATMERKLEGRDGAESLAAQREVHPKQPEPSATPQL 933
              +  M    EG  G E L ++ E  P QP PS    L
Sbjct: 414 TAQLNLMALPGEGH-GGEHLDSEGEEAP-QPMPSVPEDL 450



 Score = 34.7 bits (78), Expect = 0.44
 Identities = 21/76 (27%), Positives = 38/76 (50%)

Query: 806 EIQKLRAEISSLQRAQVQVESQLSSARRDEHRLRQQQRALEEQHSLLHAHSEQLQALYEQ 865
           +I +L+  I SL++ + QVE QL   ++  +  ++ +R LE Q   L    E+L      
Sbjct: 92  KISRLKNTIKSLKQQKKQVEHQLEEEKKANNERQKAERELEVQIQTLIIQKEELNTDLYH 151

Query: 866 KTRELQELARKLQELA 881
             R L+    + ++LA
Sbjct: 152 MERSLRYFEEESKDLA 167


>gi|156104908 myosin heavy chain 6 [Homo sapiens]
          Length = 1939

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 30/104 (28%), Positives = 54/104 (51%), Gaps = 3/104 (2%)

Query: 791  SEAVLQRGHISHLEREIQKLRAEISSLQRAQVQVESQLSSARRDEHRLRQQQRALEEQHS 850
            +E  +Q  H + +  E QK   ++ SLQ      + QL  A R    L++    +E +++
Sbjct: 1625 NEMEIQLSHANRMAAEAQK---QVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNN 1681

Query: 851  LLHAHSEQLQALYEQKTRELQELARKLQELADASENLLTENTWL 894
            LL A  E+L+A+ EQ  R  +   ++L E ++  + L ++NT L
Sbjct: 1682 LLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSL 1725



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 43/130 (33%), Positives = 64/130 (49%), Gaps = 15/130 (11%)

Query: 786  KECLQSEAVLQRGHISHLEREIQKLRAEISSLQRAQVQVESQLSSARRDEHRLRQQ---- 841
            KE L S+  L RG +S+ + +++ L+ ++    +A+  +   L SAR D   LR+Q    
Sbjct: 1296 KEALISQ--LTRGKLSYTQ-QMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEE 1352

Query: 842  -QRALEEQHSLLHAHSE--QLQALYE----QKTRELQELARKL-QELADASENLLTENTW 893
             +   E Q  L  A+SE  Q +  YE    Q+T EL+E  +KL Q L DA E +   N  
Sbjct: 1353 TEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAK 1412

Query: 894  LKILVATMER 903
               L  T  R
Sbjct: 1413 CSSLEKTKHR 1422



 Score = 38.1 bits (87), Expect = 0.040
 Identities = 29/115 (25%), Positives = 51/115 (44%), Gaps = 10/115 (8%)

Query: 803  LEREIQKLRAEISSLQRAQVQVESQLSSARRDEHRLRQQQRALE--------EQHSLLHA 854
            LE E  +L+ +I  L+    +VE +  +       L ++   L+        E+ +L  A
Sbjct: 945  LEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEA 1004

Query: 855  HSEQLQALY--EQKTRELQELARKLQELADASENLLTENTWLKILVATMERKLEG 907
            H + L  L   E K   L +   KL++  D  E  L +   +++ +   +RKLEG
Sbjct: 1005 HQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEG 1059



 Score = 34.7 bits (78), Expect = 0.44
 Identities = 29/128 (22%), Positives = 59/128 (46%), Gaps = 7/128 (5%)

Query: 786  KECLQSEAVLQRGHISHLEREI----QKLRAEISSLQRAQVQVESQLSSARRDEHRLRQQ 841
            K  L+ +  L +  I  LE +     +KL+ +   + +   ++E +   A + + +L++ 
Sbjct: 1054 KRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKEN 1113

Query: 842  QRALEEQHSLLHAHSE---QLQALYEQKTRELQELARKLQELADASENLLTENTWLKILV 898
            Q  +EE    L A      +++ L    +REL+E++ +L+E   A+   +  N   +   
Sbjct: 1114 QARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEF 1173

Query: 899  ATMERKLE 906
              M R LE
Sbjct: 1174 QKMRRDLE 1181



 Score = 30.8 bits (68), Expect = 6.3
 Identities = 35/147 (23%), Positives = 65/147 (44%), Gaps = 8/147 (5%)

Query: 778  QNVANSPTKECLQSEAVLQRGH-ISHLEREIQKLRAEISSLQRAQVQVESQLSSARRDEH 836
            Q+ A +       +++V + G  I +L+R  QKL  E S  +     V S +    + + 
Sbjct: 1186 QHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKA 1245

Query: 837  RLRQQQRALEEQHSLLHAHSEQLQALYEQKTRELQELARKLQELA---DASENLLTENTW 893
             L +  R LE+Q +      E+ Q      T +  +L  +  ELA   +  E L+++ T 
Sbjct: 1246 NLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTR 1305

Query: 894  LKI----LVATMERKLEGRDGAESLAA 916
             K+     +  ++R+LE    A++  A
Sbjct: 1306 GKLSYTQQMEDLKRQLEEEGKAKNALA 1332


>gi|42794779 myosin 18A isoform b [Homo sapiens]
          Length = 2039

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 31/96 (32%), Positives = 50/96 (52%), Gaps = 1/96 (1%)

Query: 810  LRAEISSLQRAQVQVESQLSSARRDEHRLRQQQRALEEQHSLLHAHSEQLQALYEQKTRE 869
            L  ++S LQR + +++++L   + D + L ++ +A   Q S   A    LQA  E+  +E
Sbjct: 1730 LEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKE 1789

Query: 870  LQELARKLQELADASENLLTENTWLKILVATMERKL 905
             QEL  KLQ L    E  L ++   K LV+  E K+
Sbjct: 1790 KQELQEKLQALQSQVE-FLEQSMVDKSLVSRQEAKI 1824



 Score = 32.7 bits (73), Expect = 1.7
 Identities = 18/122 (14%), Positives = 59/122 (48%), Gaps = 1/122 (0%)

Query: 789  LQSEAVLQRGHISHLEREIQKLRAEISSLQRAQVQVESQLSSARRDEHRLRQQQRALEEQ 848
            + S+       ++ ++++++ L A++   +    +    +    + + RL  +   + + 
Sbjct: 1526 ISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQT 1585

Query: 849  HSL-LHAHSEQLQALYEQKTRELQELARKLQELADASENLLTENTWLKILVATMERKLEG 907
            HS  + +  E+++   +   ++L+++  +L+E  +  + +L E   L+  +AT+  ++  
Sbjct: 1586 HSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNR 1645

Query: 908  RD 909
            RD
Sbjct: 1646 RD 1647



 Score = 30.8 bits (68), Expect = 6.3
 Identities = 28/125 (22%), Positives = 56/125 (44%), Gaps = 7/125 (5%)

Query: 789  LQSEAVLQRGHISHLEREIQKLRAEISSLQRAQVQVESQLSSARRDEHRLRQQQRALEEQ 848
            LQ+++   +  +  L+++ Q+L AE   LQ  ++ +E Q    +   H L ++QR  + +
Sbjct: 1414 LQADSEESQRALQQLKKKCQRLTAE---LQDTKLHLEGQ----QVRNHELEKKQRRFDSE 1466

Query: 849  HSLLHAHSEQLQALYEQKTRELQELARKLQELADASENLLTENTWLKILVATMERKLEGR 908
             S  H  +++ +   E+  RE   L  +   L    E    +       V ++E +L+  
Sbjct: 1467 LSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDI 1526

Query: 909  DGAES 913
               ES
Sbjct: 1527 SSQES 1531


>gi|28416946 myosin 18A isoform a [Homo sapiens]
          Length = 2054

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 31/96 (32%), Positives = 50/96 (52%), Gaps = 1/96 (1%)

Query: 810  LRAEISSLQRAQVQVESQLSSARRDEHRLRQQQRALEEQHSLLHAHSEQLQALYEQKTRE 869
            L  ++S LQR + +++++L   + D + L ++ +A   Q S   A    LQA  E+  +E
Sbjct: 1730 LEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKE 1789

Query: 870  LQELARKLQELADASENLLTENTWLKILVATMERKL 905
             QEL  KLQ L    E  L ++   K LV+  E K+
Sbjct: 1790 KQELQEKLQALQSQVE-FLEQSMVDKSLVSRQEAKI 1824



 Score = 32.7 bits (73), Expect = 1.7
 Identities = 18/122 (14%), Positives = 59/122 (48%), Gaps = 1/122 (0%)

Query: 789  LQSEAVLQRGHISHLEREIQKLRAEISSLQRAQVQVESQLSSARRDEHRLRQQQRALEEQ 848
            + S+       ++ ++++++ L A++   +    +    +    + + RL  +   + + 
Sbjct: 1526 ISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQT 1585

Query: 849  HSL-LHAHSEQLQALYEQKTRELQELARKLQELADASENLLTENTWLKILVATMERKLEG 907
            HS  + +  E+++   +   ++L+++  +L+E  +  + +L E   L+  +AT+  ++  
Sbjct: 1586 HSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNR 1645

Query: 908  RD 909
            RD
Sbjct: 1646 RD 1647



 Score = 30.8 bits (68), Expect = 6.3
 Identities = 28/125 (22%), Positives = 56/125 (44%), Gaps = 7/125 (5%)

Query: 789  LQSEAVLQRGHISHLEREIQKLRAEISSLQRAQVQVESQLSSARRDEHRLRQQQRALEEQ 848
            LQ+++   +  +  L+++ Q+L AE   LQ  ++ +E Q    +   H L ++QR  + +
Sbjct: 1414 LQADSEESQRALQQLKKKCQRLTAE---LQDTKLHLEGQ----QVRNHELEKKQRRFDSE 1466

Query: 849  HSLLHAHSEQLQALYEQKTRELQELARKLQELADASENLLTENTWLKILVATMERKLEGR 908
             S  H  +++ +   E+  RE   L  +   L    E    +       V ++E +L+  
Sbjct: 1467 LSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDI 1526

Query: 909  DGAES 913
               ES
Sbjct: 1527 SSQES 1531


>gi|194578896 golgi autoantigen, golgin subfamily a, 8E [Homo
           sapiens]
          Length = 430

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 46/158 (29%), Positives = 67/158 (42%), Gaps = 25/158 (15%)

Query: 793 AVLQRGHISHLEREIQK----LRAEISSLQRAQVQVESQLSSARRDEHRLRQQQRALEEQ 848
           AV     + HL +E+++    L+A++   QR  +  E Q    R  E RL++QQ  L EQ
Sbjct: 96  AVPSEVELQHLRKELERVAGALQAQVEYNQRISLLNEGQKERLREQEERLQEQQERLREQ 155

Query: 849 HSLLHAHSEQLQAL------------YEQKTRELQE-LARKLQELADASENLLTENTWLK 895
              L   +E   +              EQ+ +ELQE L ++  E A   +  LT    L 
Sbjct: 156 EERLQQLAEPQNSFKELNNENKSVLQLEQQVKELQEKLGKERLEAASQQKQQLTAQLSLM 215

Query: 896 ILVATMERKLEGRDGAESLAAQREVHPKQPEPSATPQL 933
            L        EG  G E L ++ E  P+ P PS    L
Sbjct: 216 ALPG------EGH-GGEHLDSEGEEAPR-PMPSVPEDL 245


>gi|169208517 PREDICTED: similar to Golgin subfamily A member 8-like
           protein 1 isoform 2 [Homo sapiens]
          Length = 602

 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 38/142 (26%), Positives = 69/142 (48%), Gaps = 11/142 (7%)

Query: 768 LHHSDPASSPQNVANSPTKECLQSEAVLQRGHISHLEREIQKLRAEISSLQRAQVQVESQ 827
           L+ S  + S  +  ++P   C +   VL    +     EI +L+  I SL++ + QVE Q
Sbjct: 58  LYLSPDSCSTSSSLHAPQSPCQERAVVLDSRSV-----EISQLKNTIKSLKQQKKQVEHQ 112

Query: 828 LSSARRDEHRLRQQQRALEEQHSLLHAHSEQLQA-LYEQKTRELQELARKLQELADASEN 886
           L   ++  ++ ++ +R LE Q   L+   E+L   LY  K R L+    K ++LA   ++
Sbjct: 113 LEEEKKANNKKQKAKRVLEVQLQTLNIQKEELNTDLYHMK-RSLRYFEEKSKDLAVRLQH 171

Query: 887 LLTE----NTWLKILVATMERK 904
            L       + L  ++AT ++K
Sbjct: 172 SLQRKGELESVLSDVMATQKKK 193



 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 30/105 (28%), Positives = 54/105 (51%), Gaps = 4/105 (3%)

Query: 784 PTKECLQSEAVLQRGHI-SHLEREIQKLRAEISSLQRAQVQVESQLSSARRDEHRLRQQQ 842
           P    + SE  LQ  H+   LER   +L+A++ + QR  +  + Q    R  E RLR+Q+
Sbjct: 296 PEPPAVPSEVELQ--HLRKELERVAGELQAQVKNNQRISLLNQRQEERIREQEERLRKQE 353

Query: 843 RALEEQHSLLHAHSEQLQALYEQKTRELQELARKLQELADASENL 887
             ++EQH  L   ++  Q+++E+   E +   +  Q++ +  E L
Sbjct: 354 ERIQEQHKSLQQLAKP-QSVFEEPNNENKSTLQLEQQVKELQEKL 397


>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
            sapiens]
          Length = 1940

 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 35/109 (32%), Positives = 56/109 (51%), Gaps = 8/109 (7%)

Query: 800  ISHLEREIQKLRAEISSLQRAQVQVESQLSSARRDEHRLRQQQRALEEQHSLLHAHSEQL 859
            +SH  R+  +    + S+Q      +  L  A R +  L++Q   +E + +LL A  E+L
Sbjct: 1630 LSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEEL 1689

Query: 860  QALYEQKTRELQELARKL--QELADASENLLTENTWLKILVATMERKLE 906
            +A  EQ  R     ARKL  QEL D++E +   +T    L+ T ++KLE
Sbjct: 1690 RATLEQTER-----ARKLAEQELLDSNERVQLLHTQNTSLIHT-KKKLE 1732



 Score = 38.9 bits (89), Expect = 0.023
 Identities = 29/115 (25%), Positives = 52/115 (45%), Gaps = 10/115 (8%)

Query: 803  LEREIQKLRAEISSLQRAQVQVESQLSSARRDEHRLRQQQRALE--------EQHSLLHA 854
            LE E  +L+ +I  L+    +VE +  +       L ++   L+        E+ +L  A
Sbjct: 944  LEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEA 1003

Query: 855  HSEQLQALY--EQKTRELQELARKLQELADASENLLTENTWLKILVATMERKLEG 907
            H + L  L   E K   L +   KL++  +  E+ L +   L++ +   +RKLEG
Sbjct: 1004 HQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEG 1058



 Score = 38.1 bits (87), Expect = 0.040
 Identities = 36/134 (26%), Positives = 62/134 (46%), Gaps = 8/134 (5%)

Query: 791  SEAVLQRGH-ISHLEREIQKLRAEISSLQRAQVQVESQLSSARRDEHRLRQQQRALEEQH 849
            +++V + G  I +L+R  QKL  E S  +     + S + S  + +  L +  R LE+Q 
Sbjct: 1198 ADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQL 1257

Query: 850  SLLHAHSEQLQ----ALYEQKTR---ELQELARKLQELADASENLLTENTWLKILVATME 902
            S     +E++Q     L  QK+R   E  EL+R+L+E       L             ++
Sbjct: 1258 SEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELK 1317

Query: 903  RKLEGRDGAESLAA 916
            R+LE  + A++  A
Sbjct: 1318 RQLEEENKAKNALA 1331



 Score = 38.1 bits (87), Expect = 0.040
 Identities = 40/132 (30%), Positives = 64/132 (48%), Gaps = 21/132 (15%)

Query: 805  REIQKLRAEISSLQRAQVQVESQLSSARRDEHRLRQQQRALEE-----QHSLLHAHSE-- 857
            ++ ++L+ ++    +A+  +   L S+R D   LR+Q    +E     Q +L  A+SE  
Sbjct: 1311 QQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVA 1370

Query: 858  QLQALYE----QKTRELQELARKL-QELADASENLLTENTWLKILVATMERKLEGR---- 908
            Q +  YE    Q+T EL+E  +KL Q L D+ E +   N     L  T +R L+G     
Sbjct: 1371 QWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQR-LQGEVEDL 1429

Query: 909  ----DGAESLAA 916
                + A SLAA
Sbjct: 1430 MVDVERANSLAA 1441



 Score = 36.2 bits (82), Expect = 0.15
 Identities = 29/110 (26%), Positives = 47/110 (42%), Gaps = 5/110 (4%)

Query: 778  QNVANSPTKECLQSEAVLQRGHISHLEREIQKLRAEISSLQRAQVQVESQLSSARRDEHR 837
            Q V     KE  +SE  L+   +S     + K +A +  + R    +E QLS AR     
Sbjct: 1212 QRVKQKLEKE--KSEFKLEIDDLSSSMESVSKSKANLEKICRT---LEDQLSEARGKNEE 1266

Query: 838  LRQQQRALEEQHSLLHAHSEQLQALYEQKTRELQELARKLQELADASENL 887
            +++    L  Q S L   + +L    E+K   + +L+R  Q     +E L
Sbjct: 1267 IQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEEL 1316



 Score = 35.0 bits (79), Expect = 0.34
 Identities = 33/144 (22%), Positives = 61/144 (42%), Gaps = 17/144 (11%)

Query: 786  KECLQSEAVLQRGHISHLEREIQKLRAEISSLQRAQVQVESQLSSARRDEHRLRQQQRAL 845
            +E L+ +  +     + L+ E+++LRA +   +RA+   E +L  +      L  Q  +L
Sbjct: 1665 QEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSL 1724

Query: 846  EEQHSLLHAHSEQLQALYEQKTRELQE--------------LARKLQELADASENLLTEN 891
                  L     QLQ+  E  +R+ +               +A +L++  D S +L    
Sbjct: 1725 IHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMK 1784

Query: 892  TWLKILVATMERKLEGRDGAESLA 915
              L+  V  ++ +L   D AE LA
Sbjct: 1785 KNLEQTVKDLQHRL---DEAEQLA 1805



 Score = 31.2 bits (69), Expect = 4.8
 Identities = 29/128 (22%), Positives = 58/128 (45%), Gaps = 7/128 (5%)

Query: 786  KECLQSEAVLQRGHISHLEREIQKL--RAEISSLQRAQVQ--VESQLSSARRDEHRLRQQ 841
            K  L+ +  L +  I  LE + Q+L  R +    +  Q+Q  VE + +   + + ++++ 
Sbjct: 1053 KRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKEL 1112

Query: 842  QRALEEQHSLLHAHSEQLQALYEQKT---RELQELARKLQELADASENLLTENTWLKILV 898
            Q  +EE    + A         +Q++   REL+EL+ +L+E    +   +  N   +   
Sbjct: 1113 QARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEF 1172

Query: 899  ATMERKLE 906
              + R LE
Sbjct: 1173 LKLRRDLE 1180



 Score = 30.4 bits (67), Expect = 8.3
 Identities = 26/124 (20%), Positives = 54/124 (43%), Gaps = 4/124 (3%)

Query: 803  LEREIQKLRAEISSLQRAQVQVESQLSSARRDEHRLRQQQRALEEQHSLLHAHSEQLQAL 862
            LE ++ +L++E+    R     E +   A  D   + ++ +  +EQ +   AH E+++  
Sbjct: 1731 LETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELK--KEQDT--SAHLERMKKN 1786

Query: 863  YEQKTRELQELARKLQELADASENLLTENTWLKILVATMERKLEGRDGAESLAAQREVHP 922
             EQ  ++LQ    + ++LA        +    +I     E + E +   ES+   R+   
Sbjct: 1787 LEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYER 1846

Query: 923  KQPE 926
            +  E
Sbjct: 1847 RVKE 1850


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.134    0.405 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,435,592
Number of Sequences: 37866
Number of extensions: 1834502
Number of successful extensions: 15987
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 287
Number of HSP's successfully gapped in prelim test: 530
Number of HSP's that attempted gapping in prelim test: 12173
Number of HSP's gapped (non-prelim): 3650
length of query: 958
length of database: 18,247,518
effective HSP length: 112
effective length of query: 846
effective length of database: 14,006,526
effective search space: 11849520996
effective search space used: 11849520996
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.