Guide to the Human Genome
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Search of human proteins with 54607116

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|54607116 leiomodin 3 (fetal) [Homo sapiens]
         (560 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|54607116 leiomodin 3 (fetal) [Homo sapiens]                       1121   0.0  
gi|150378503 leiomodin 2 (cardiac) [Homo sapiens]                     336   3e-92
gi|112380630 leiomodin 1 (smooth muscle) [Homo sapiens]               278   7e-75
gi|7657647 neuronal tropomodulin isoform a [Homo sapiens]             198   1e-50
gi|156415984 tropomodulin 4 (muscle) [Homo sapiens]                   182   9e-46
gi|4507553 tropomodulin 1 [Homo sapiens]                              160   4e-39
gi|7657649 tropomodulin 3 (ubiquitous) [Homo sapiens]                 159   5e-39
gi|218931148 neuronal tropomodulin isoform b [Homo sapiens]           152   6e-37
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]           65   1e-10
gi|17975763 myelin transcription factor 1 [Homo sapiens]               61   2e-09
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]           59   2e-08
gi|115511012 coiled-coil domain containing 136 [Homo sapiens]          58   3e-08
gi|115529449 upstream binding transcription factor, RNA polymera...    56   1e-07
gi|115529451 upstream binding transcription factor, RNA polymera...    56   1e-07
gi|7657671 upstream binding transcription factor, RNA polymerase...    56   1e-07
gi|221219020 NYD-SP11 protein [Homo sapiens]                           54   3e-07
gi|60498973 myelin transcription factor 1-like [Homo sapiens]          54   3e-07
gi|22758136 MAP7 domain containing 2 [Homo sapiens]                    54   4e-07
gi|194294523 intersectin 2 isoform 3 [Homo sapiens]                    54   5e-07
gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens]     54   5e-07
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]    53   6e-07
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]    53   6e-07
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi...    53   8e-07
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap...    53   8e-07
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li...    52   1e-06
gi|55956788 nucleolin [Homo sapiens]                                   52   1e-06
gi|190014588 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo...    52   1e-06
gi|19923653 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo ...    52   1e-06
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)...    52   1e-06
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li...    52   2e-06

>gi|54607116 leiomodin 3 (fetal) [Homo sapiens]
          Length = 560

 Score = 1121 bits (2900), Expect = 0.0
 Identities = 560/560 (100%), Positives = 560/560 (100%)

Query: 1   MSEHSRNSDQEELLDEEINEDEILANLSAEELKELQSEMEVMAPDPSLPVGMIQKDQTDK 60
           MSEHSRNSDQEELLDEEINEDEILANLSAEELKELQSEMEVMAPDPSLPVGMIQKDQTDK
Sbjct: 1   MSEHSRNSDQEELLDEEINEDEILANLSAEELKELQSEMEVMAPDPSLPVGMIQKDQTDK 60

Query: 61  PPTGNFNHKSLVDYMYWEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLK 120
           PPTGNFNHKSLVDYMYWEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLK
Sbjct: 61  PPTGNFNHKSLVDYMYWEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLK 120

Query: 121 EKLNNEIVANKRESKGSSNIQETDEEDEEEEDDDDDDEGEDDGEESEETNREEEGKAKEQ 180
           EKLNNEIVANKRESKGSSNIQETDEEDEEEEDDDDDDEGEDDGEESEETNREEEGKAKEQ
Sbjct: 121 EKLNNEIVANKRESKGSSNIQETDEEDEEEEDDDDDDEGEDDGEESEETNREEEGKAKEQ 180

Query: 181 IRNCENNCQQVTDKAFKEQRDRPEAQEQSEKKISKLDPKKLALDTSFLKVSTRPSGNQTD 240
           IRNCENNCQQVTDKAFKEQRDRPEAQEQSEKKISKLDPKKLALDTSFLKVSTRPSGNQTD
Sbjct: 181 IRNCENNCQQVTDKAFKEQRDRPEAQEQSEKKISKLDPKKLALDTSFLKVSTRPSGNQTD 240

Query: 241 LDGSLRRVRKNDPDMKELNLNNIENIPKEMLLDFVNAMKKNKHIKTFSLANVGADENVAF 300
           LDGSLRRVRKNDPDMKELNLNNIENIPKEMLLDFVNAMKKNKHIKTFSLANVGADENVAF
Sbjct: 241 LDGSLRRVRKNDPDMKELNLNNIENIPKEMLLDFVNAMKKNKHIKTFSLANVGADENVAF 300

Query: 301 ALANMLRENRSITTLNIESNFITGKGIVAIMRCLQFNETLTELRFHNQRHMLGHHAEMEI 360
           ALANMLRENRSITTLNIESNFITGKGIVAIMRCLQFNETLTELRFHNQRHMLGHHAEMEI
Sbjct: 301 ALANMLRENRSITTLNIESNFITGKGIVAIMRCLQFNETLTELRFHNQRHMLGHHAEMEI 360

Query: 361 ARLLKANNTLLKMGYHFELPGPRMVVTNLLTRNQDKQRQKRQEEQKQQQLKEQKKLIAML 420
           ARLLKANNTLLKMGYHFELPGPRMVVTNLLTRNQDKQRQKRQEEQKQQQLKEQKKLIAML
Sbjct: 361 ARLLKANNTLLKMGYHFELPGPRMVVTNLLTRNQDKQRQKRQEEQKQQQLKEQKKLIAML 420

Query: 421 ENGLGLPPGMWELLGGPKPDSRMQEFFQPPPPRPPNPQNVPFSQRSEMMKKPSQAPKYRT 480
           ENGLGLPPGMWELLGGPKPDSRMQEFFQPPPPRPPNPQNVPFSQRSEMMKKPSQAPKYRT
Sbjct: 421 ENGLGLPPGMWELLGGPKPDSRMQEFFQPPPPRPPNPQNVPFSQRSEMMKKPSQAPKYRT 480

Query: 481 DPDSFRVVKLKRIQRKSRMPEAREPPEKTNLKDVIKTLKPVPRNRPPPLVEITPRDQLLN 540
           DPDSFRVVKLKRIQRKSRMPEAREPPEKTNLKDVIKTLKPVPRNRPPPLVEITPRDQLLN
Sbjct: 481 DPDSFRVVKLKRIQRKSRMPEAREPPEKTNLKDVIKTLKPVPRNRPPPLVEITPRDQLLN 540

Query: 541 DIRHSSVAYLKPVQLPKELA 560
           DIRHSSVAYLKPVQLPKELA
Sbjct: 541 DIRHSSVAYLKPVQLPKELA 560


>gi|150378503 leiomodin 2 (cardiac) [Homo sapiens]
          Length = 547

 Score =  336 bits (862), Expect = 3e-92
 Identities = 218/583 (37%), Positives = 314/583 (53%), Gaps = 89/583 (15%)

Query: 16  EEINEDEILANLSAEELKELQSEMEVMAPDPSLPVGMIQKDQTDKPPTGNFNHKSLVDYM 75
           E I+EDE+LA+LSAEELKEL+ E+E + PD +LPVG+ QK  T+K PTG F+ ++L+   
Sbjct: 14  ESIDEDELLASLSAEELKELERELEDIEPDRNLPVGLRQKSLTEKTPTGTFSREALM--A 71

Query: 76  YWEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRESK 135
           YWEK S+++LE+ER+      +E+K  EE EE                  E++  +  S+
Sbjct: 72  YWEKESQKLLEKERLGECGKVAEDK--EESEE------------------ELIFTESNSE 111

Query: 136 GSSNIQETDEEDEEEEDDDDDDEGEDDGEESEETNREEEGKAKEQIRNCENNCQQVTDKA 195
            S  +   +EE+E +E+++++D  E+  E + ET +   G       N +N+      K 
Sbjct: 112 VSEEVYTEEEEEESQEEEEEEDSDEE--ERTIETAKGINGTVNYDSVNSDNS----KPKI 165

Query: 196 FKEQRDRPEAQEQSEKKISKLDPKKLALDTSFLKVSTRPSGNQTDLDGSLRRVRKNDPDM 255
           FK Q +       S  + ++               +  P GN T ++ +L +++ NDPD 
Sbjct: 166 FKSQIENINLTNGSNGRNTESP------------AAIHPCGNPTVIEDALDKIKSNDPDT 213

Query: 256 KELNLNNIENIPKEMLLDFVNAMKKNKHIKTFSLANVGADENVAFALANMLRENRSITTL 315
            E+NLNNIENI  + L  F  A+K N  +KTFSLAN  AD++ A A+A ML+ N  IT +
Sbjct: 214 TEVNLNNIENITTQTLTRFAEALKDNTVVKTFSLANTHADDSAAMAIAEMLKVNEHITNV 273

Query: 316 NIESNFITGKGIVAIMRCLQFNETLTELRFHNQRHMLGHHAEMEIARLLKANNTLLKMGY 375
           N+ESNFITGKGI+AIMR LQ N  LTELRFHNQRH++G   EMEI +LLK N TLL++GY
Sbjct: 274 NVESNFITGKGILAIMRALQHNTVLTELRFHNQRHIMGSQVEMEIVKLLKENTTLLRLGY 333

Query: 376 HFELPGPRMVVTNLLTRNQDKQRQKRQEEQKQQQLKEQKKLIAMLENGLGLPPGMWEL-- 433
           HFELPGPRM +T++LTRN DKQRQKR +EQKQQ+           + G  L   +W+   
Sbjct: 334 HFELPGPRMSMTSILTRNMDKQRQKRLQEQKQQE---------GYDGGPNLRTKVWQRGT 384

Query: 434 -------------LGGPKPDSRMQ--------EFFQPPPPRPPNPQNVPFSQRSEMMKKP 472
                           PK   ++Q            PPPP PP P   P SQR      P
Sbjct: 385 PSSSPYVSPRHSPWSSPKLPKKVQTVRSRPLSPVATPPPPPPPPPPPPPSSQRLPPPPPP 444

Query: 473 SQAP---KYRTDPDSFRVVK--------LKRIQRKSRMPEAREPPEKTNLKDVIKTLKPV 521
              P   K     +   V+K        L+  Q+K +  + ++ P    LK++  +L+ V
Sbjct: 445 PPPPLPEKKLITRNIAEVIKQQESAQRALQNGQKKKKGKKVKKQPNSI-LKEIKNSLRSV 503

Query: 522 PRNR-----PPPLVEITPRDQLLNDIRHSSVAYLKPVQLPKEL 559
              +      P   + +  + L+  IR SS+  LK V++P+ L
Sbjct: 504 QEKKMEDSSRPSTPQRSAHENLMEAIRGSSIKQLKRVEVPEAL 546


>gi|112380630 leiomodin 1 (smooth muscle) [Homo sapiens]
          Length = 600

 Score =  278 bits (712), Expect = 7e-75
 Identities = 214/643 (33%), Positives = 319/643 (49%), Gaps = 133/643 (20%)

Query: 5   SRNSDQEELLDEEINEDEILANLSAEELKELQSEMEVMAPDPSLPVGMIQKDQTDKPPTG 64
           SR +     + E+ + D +L  LS EE++EL+ E++V+ PD S+PVG+ Q++QT+K  TG
Sbjct: 2   SRVAKYRRQVSEDPDIDSLLETLSPEEMEELEKELDVVDPDGSVPVGLRQRNQTEKQSTG 61

Query: 65  NFNHKSLVDYMYWEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRN------------ 112
            +N ++++++   EK ++++++ E       + E KT  ++ E   R+            
Sbjct: 62  VYNREAMLNFC--EKETKKLMQREMSMDESKQVETKTDAKNGEERGRDASKKALGPRRDS 119

Query: 113 ------------------------KNMAQYLKEKLNNEI-------VANKRES----KGS 137
                                   K+  +  +EK+   I         +K+E+    +G 
Sbjct: 120 DLGKEPKRGGLKKSFSRDRDEAGGKSGEKPKEEKIIRGIDKGRVRAAVDKKEAGKDGRGE 179

Query: 138 SNIQETDEEDEEEEDDDDDDEGEDDGEESEE----TNREEEGKAKEQIRNCE-------- 185
                T +E+E++  D +     D  ++ EE      +E++ K K + RN +        
Sbjct: 180 ERAVATKKEEEKKGSDRNTGLSRDKDKKREEMKEVAKKEDDEKVKGERRNTDTRKEGEKM 239

Query: 186 -----NNCQQVTDKAFKEQRDRPEAQEQSEKKISKLDP--KKLALDTSFLKVSTR--PSG 236
                N   +  D+  K      + ++  EK + K +P  +K A D S  K   +  PSG
Sbjct: 240 KRAGGNTDMKKEDEKVKRGTGNTDTKKDDEK-VKKNEPLHEKEAKDDSKTKTPEKQTPSG 298

Query: 237 NQTDLDGS---------------LRRVRKNDPDMKELNLNNIENIPKEMLLDFVNAMKKN 281
                +G                L RV+ NDP+M E+N+NN + I  E+L+ F  A++ N
Sbjct: 299 PTKPSEGPAKVEEEAAPSIFDEPLERVKNNDPEMTEVNVNNSDCITNEILVRFTEALEFN 358

Query: 282 KHIKTFSLANVGADENVAFALANMLRENRSITTLNIESNFITGKGIVAIMRCLQFNETLT 341
             +K F+LAN  AD++VAFA+A ML+ N++IT+LN++SN ITGKGI+AI R L  N TLT
Sbjct: 359 TVVKLFALANTRADDHVAFAIAIMLKANKTITSLNLDSNHITGKGILAIFRALLQNNTLT 418

Query: 342 ELRFHNQRHMLGHHAEMEIARLLKANNTLLKMGYHFELPGPRMVVTNLLTRNQDKQRQKR 401
           ELRFHNQRH+ G   EMEIA+LLK N TLLK+GYHFEL GPRM VTNLL+RN DKQRQKR
Sbjct: 419 ELRFHNQRHICGGKTEMEIAKLLKENTTLLKLGYHFELAGPRMTVTNLLSRNMDKQRQKR 478

Query: 402 QEEQKQ-QQLKEQKKLIAMLENGLGLPPGMWELLGGPKPDSRMQEFFQPPPPRPPNPQNV 460
            +EQ+Q Q+ K +KK +      L +P       G PKP         P P   P+P+N 
Sbjct: 479 LQEQRQAQEAKGEKKDL------LEVPKAGAVAKGSPKP--------SPQPSPKPSPKNS 524

Query: 461 PFSQRSEMMKKPSQAPKYRTDPDSFRVVKLKRIQRKSRMPEAREPPEKTNLKDVIKTLKP 520
           P         K   AP     P                 P    P    NLK+   +L P
Sbjct: 525 P---------KKGGAPAAPPPPP----------------PPLAPPLIMENLKN---SLSP 556

Query: 521 VPR----NRPPPLVEITPRDQLLNDIRHSSVAYLKPVQLPKEL 559
             +    ++  P  E   RDQLL  IR S++  LK V++PK L
Sbjct: 557 ATQRKMGDKVLPAQEKNSRDQLLAAIRSSNLKQLKKVEVPKLL 599


>gi|7657647 neuronal tropomodulin isoform a [Homo sapiens]
          Length = 351

 Score =  198 bits (504), Expect = 1e-50
 Identities = 135/393 (34%), Positives = 206/393 (52%), Gaps = 55/393 (13%)

Query: 16  EEINEDEILANLSAEELKELQSEMEVMAPDPS-LPVGMIQKDQTDKPPTGNFNHKSLVDY 74
           + I+EDE+L  LS EELK+L++ ++ + P+ + LP G  QKDQT K  TG F+ + L+ Y
Sbjct: 13  KNIDEDELLGKLSEEELKQLENVLDDLDPESAMLPAGFRQKDQTQKAATGPFDREHLLMY 72

Query: 75  MYWEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRES 134
                     LE+E +       E+K +E+        K      KEK     +  ++E 
Sbjct: 73  ----------LEKEAL-------EQKDREDFVPFTGEKKGRVFIPKEKP----IETRKEE 111

Query: 135 KGSSNIQETDEEDEEEEDDDDDDEGEDDGEESEETNREEEGKAKEQIRNCENNCQQVTDK 194
           K +      D E EE      D E  D               A   + N  NN       
Sbjct: 112 KVT-----LDPELEEALASASDTELYDLA-------------AVLGVHNLLNN------- 146

Query: 195 AFKEQRDRPEAQEQSEKKISKLDPKKLALDTSFLKVSTRPSGNQTDLDGSLRRVRKNDPD 254
                   P+  E++        P +  +    +K       N T+++ SL++++ NDP 
Sbjct: 147 --------PKFDEETANNKGGKGPVRNVVKGEKVKPVFEEPPNPTNVEISLQQMKANDPS 198

Query: 255 MKELNLNNIENIPKEMLLDFVNAMKKNKHIKTFSLANVGADENVAFALANMLRENRSITT 314
           ++E+NLNNI+NIP   L +F  A++ N H+K FSLA   +++ VA A A+ML+ N+++T+
Sbjct: 199 LQEVNLNNIKNIPIPTLREFAKALETNTHVKKFSLAATRSNDPVAIAFADMLKVNKTLTS 258

Query: 315 LNIESNFITGKGIVAIMRCLQFNETLTELRFHNQRHMLGHHAEMEIARLLKANNTLLKMG 374
           LNIESNFITG GI+A++  L+ N+TLTE++  NQR  LG   EMEIA++L+ N+ +LK G
Sbjct: 259 LNIESNFITGTGILALVEALKENDTLTEIKIDNQRQQLGTAVEMEIAQMLEENSRILKFG 318

Query: 375 YHFELPGPRMVVTNLLTRNQDKQRQKRQEEQKQ 407
           Y F   GPR  V   +T+N D  R+KR E  ++
Sbjct: 319 YQFTKQGPRTRVAAAITKNNDLVRKKRVEADRR 351


>gi|156415984 tropomodulin 4 (muscle) [Homo sapiens]
          Length = 345

 Score =  182 bits (461), Expect = 9e-46
 Identities = 127/402 (31%), Positives = 197/402 (49%), Gaps = 65/402 (16%)

Query: 7   NSDQEELLD-EEINEDEILANLSAEELKELQSEMEVMAPDPSL-PVGMIQKDQTDKPPTG 64
           +S Q+EL    +I+EDEIL  LS EEL++L  E++ M P+  L P G+ Q+DQT K PTG
Sbjct: 2   SSYQKELEKYRDIDEDEILRTLSPEELEQLDCELQEMDPENMLLPAGLRQRDQTKKSPTG 61

Query: 65  NFNHKSLVDYMYWEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLN 124
             + ++L+ Y          LE++ + V                 K   ++  +  EK  
Sbjct: 62  PLDREALLQY----------LEQQALEV-----------------KERDDLVPFTGEKKG 94

Query: 125 NEIVANKRESKGSSNIQETDEEDEEEEDDDD----DDEGEDDGEESEETNREEEGKAKEQ 180
              +  KRE      I    E +E      D    D     D        +  +     +
Sbjct: 95  KPYIQPKREIPAEEQITLEPELEEALAHATDAEMCDIAAILDMYTLMSNKQYYDALCSGE 154

Query: 181 IRNCENNCQQVTDKAFKEQRDRPEAQEQSEKKISKLDPKKLALDTSFLKVSTRPSGNQTD 240
           I N E     V    +K   D P                                 N T+
Sbjct: 155 ICNTEGISSVVQPDKYKPVPDEPP--------------------------------NPTN 182

Query: 241 LDGSLRRVRKNDPDMKELNLNNIENIPKEMLLDFVNAMKKNKHIKTFSLANVGADENVAF 300
           ++  L+RVR ND +++E+NLNNI++IP  ML +   AMK N ++++FSL    + + +A 
Sbjct: 183 IEEILKRVRSNDKELEEVNLNNIQDIPIPMLSELCEAMKANTYVRSFSLVATRSGDPIAN 242

Query: 301 ALANMLRENRSITTLNIESNFITGKGIVAIMRCLQFNETLTELRFHNQRHMLGHHAEMEI 360
           A+A+MLRENRS+ +LNIESNFI+  G++A+++ ++ N TLTELR  NQR   G   EME+
Sbjct: 243 AVADMLRENRSLQSLNIESNFISSTGLMAVLKAVRENATLTELRVDNQRQWPGDAVEMEM 302

Query: 361 ARLLKANNTLLKMGYHFELPGPRMVVTNLLTRNQDKQRQKRQ 402
           A +L+   ++++ GYHF   GPR      +TRN + +RQ+++
Sbjct: 303 ATVLEQCPSIVRFGYHFTQQGPRARAAQAMTRNNELRRQQKK 344


>gi|4507553 tropomodulin 1 [Homo sapiens]
          Length = 359

 Score =  160 bits (404), Expect = 4e-39
 Identities = 74/165 (44%), Positives = 112/165 (67%)

Query: 237 NQTDLDGSLRRVRKNDPDMKELNLNNIENIPKEMLLDFVNAMKKNKHIKTFSLANVGADE 296
           N TD++ +L R++ NDP ++E+NLNNI NIP   L  +  A+K+N ++K FS+    +++
Sbjct: 179 NSTDVEETLERIKNNDPKLEEVNLNNIRNIPIPTLKAYAEALKENSYVKKFSIVGTRSND 238

Query: 297 NVAFALANMLRENRSITTLNIESNFITGKGIVAIMRCLQFNETLTELRFHNQRHMLGHHA 356
            VA+ALA ML+EN+ + TLN+ESNFI+G GI+ ++  L +N +L E++  NQ   LG+  
Sbjct: 239 PVAYALAEMLKENKVLKTLNVESNFISGAGILRLVEALPYNTSLVEMKIDNQSQPLGNKV 298

Query: 357 EMEIARLLKANNTLLKMGYHFELPGPRMVVTNLLTRNQDKQRQKR 401
           EMEI  +L+ N TLLK GYHF   GPR+  +N +  N D  R++R
Sbjct: 299 EMEIVSMLEKNATLLKFGYHFTQQGPRLRASNAMMNNNDLVRKRR 343


>gi|7657649 tropomodulin 3 (ubiquitous) [Homo sapiens]
          Length = 352

 Score =  159 bits (403), Expect = 5e-39
 Identities = 79/171 (46%), Positives = 115/171 (67%)

Query: 237 NQTDLDGSLRRVRKNDPDMKELNLNNIENIPKEMLLDFVNAMKKNKHIKTFSLANVGADE 296
           N T+++ SL+R ++ND  + E+NLNNI+NIP   L DF  A++ N H+K FSLA   +++
Sbjct: 182 NPTNVEESLKRTKENDAHLVEVNLNNIKNIPIPTLKDFAKALETNTHVKCFSLAATRSND 241

Query: 297 NVAFALANMLRENRSITTLNIESNFITGKGIVAIMRCLQFNETLTELRFHNQRHMLGHHA 356
            VA A A ML+ N+++ +LN+ESNFITG GI+A++  L+ NETL EL+  NQR  LG   
Sbjct: 242 PVATAFAEMLKVNKTLKSLNVESNFITGVGILALIDALRDNETLAELKIDNQRQQLGTAV 301

Query: 357 EMEIARLLKANNTLLKMGYHFELPGPRMVVTNLLTRNQDKQRQKRQEEQKQ 407
           E+E+A++L+ N  +LK GY F   GPR    N +T+N D  R++R E   Q
Sbjct: 302 ELEMAKMLEENTNILKFGYQFTQQGPRTRAANAITKNNDLVRKRRVEGDHQ 352


>gi|218931148 neuronal tropomodulin isoform b [Homo sapiens]
          Length = 315

 Score =  152 bits (385), Expect = 6e-37
 Identities = 120/393 (30%), Positives = 184/393 (46%), Gaps = 91/393 (23%)

Query: 16  EEINEDEILANLSAEELKELQSEMEVMAPDPS-LPVGMIQKDQTDKPPTGNFNHKSLVDY 74
           + I+EDE+L  LS EELK+L++ ++ + P+ + LP G  QKDQT K  TG F+ + L+ Y
Sbjct: 13  KNIDEDELLGKLSEEELKQLENVLDDLDPESAMLPAGFRQKDQTQKAATGPFDREHLLMY 72

Query: 75  MYWEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRES 134
                     LE+E +       E+K +E+        K      KEK     +  ++E 
Sbjct: 73  ----------LEKEAL-------EQKDREDFVPFTGEKKGRVFIPKEKP----IETRKEE 111

Query: 135 KGSSNIQETDEEDEEEEDDDDDDEGEDDGEESEETNREEEGKAKEQIRNCENNCQQVTDK 194
           K +      D E EE      D E  D               A   + N  NN       
Sbjct: 112 KVT-----LDPELEEALASASDTELYDLA-------------AVLGVHNLLNN------- 146

Query: 195 AFKEQRDRPEAQEQSEKKISKLDPKKLALDTSFLKVSTRPSGNQTDLDGSLRRVRKNDPD 254
                   P+  E++        P +  +    +K       N T+++ SL++++ NDP 
Sbjct: 147 --------PKFDEETANNKGGKGPVRNVVKGEKVKPVFEEPPNPTNVEISLQQMKANDPS 198

Query: 255 MKELNLNNIENIPKEMLLDFVNAMKKNKHIKTFSLANVGADENVAFALANMLRENRSITT 314
           ++E+NLNNI+                                    A A+ML+ N+++T+
Sbjct: 199 LQEVNLNNIK------------------------------------AFADMLKVNKTLTS 222

Query: 315 LNIESNFITGKGIVAIMRCLQFNETLTELRFHNQRHMLGHHAEMEIARLLKANNTLLKMG 374
           LNIESNFITG GI+A++  L+ N+TLTE++  NQR  LG   EMEIA++L+ N+ +LK G
Sbjct: 223 LNIESNFITGTGILALVEALKENDTLTEIKIDNQRQQLGTAVEMEIAQMLEENSRILKFG 282

Query: 375 YHFELPGPRMVVTNLLTRNQDKQRQKRQEEQKQ 407
           Y F   GPR  V   +T+N D  R+KR E  ++
Sbjct: 283 YQFTKQGPRTRVAAAITKNNDLVRKKRVEADRR 315


>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
          Length = 709

 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 68/288 (23%), Positives = 121/288 (42%), Gaps = 33/288 (11%)

Query: 107 EIEKRNKNMAQYLKEKLNNEIVANKRE--SKGSSN------------IQETDEEDEE-EE 151
           E+++R    +Q  KE++N+E   +  E  S GSS+            ++E  EEDEE EE
Sbjct: 158 EVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEE 217

Query: 152 DDDDDDEGEDDGEESEETNREEEGKAKEQIRNCENNCQQVTDKAFKEQRDRPEAQEQSEK 211
           D ++D+E ++DGEE EE   EEE + +E+    E           +++RD+ E     + 
Sbjct: 218 DAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYE-----------QDERDQKEEGNDYDT 266

Query: 212 KISKLDPKKLALDTSFLKVSTRPSGNQTDLDGSLRRVRKNDPDMKELNLNNIENIPKEML 271
           +    D    ++  SF   S R SG+ TD     ++ RK    +  +  +   +   E  
Sbjct: 267 RSEASDSGSESV--SFTDGSVR-SGSGTDGSDEKKKERKRARGISPIVFDRSGSSASESY 323

Query: 272 LDFVNAMKKNKHIKTFSLANVGADENVAFALANMLRENRSITTLNIESNFITGKGIVAIM 331
            D  + +K       F L      ENV+ A A  +     +    +   F + + ++ I 
Sbjct: 324 ADQTSKLKYVLQDARFFLIKSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRSARSVILIF 383

Query: 332 RCLQFNETLTELRFHNQRHMLGHHAEMEIARLLKANNTLLKMGYHFEL 379
              +  +     R  ++     HH    I  +L A  +   +G  F++
Sbjct: 384 SVRESGKFQGFARLSSE----SHHGGSPIHWVLPAGMSAKMLGGVFKI 427


>gi|17975763 myelin transcription factor 1 [Homo sapiens]
          Length = 1121

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 37/133 (27%), Positives = 65/133 (48%), Gaps = 4/133 (3%)

Query: 78  EKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRESKGS 137
           ++A+     EE     F++ E+  +      E+      Q L++  + E      + KG 
Sbjct: 199 QEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEE----SSKQKGI 254

Query: 138 SNIQETDEEDEEEEDDDDDDEGEDDGEESEETNREEEGKAKEQIRNCENNCQQVTDKAFK 197
            + +E DEE+EEEE+++++DE E++ EE EE   EEE + +E+    E   +   D  F+
Sbjct: 255 LSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQ 314

Query: 198 EQRDRPEAQEQSE 210
           E      AQ+  E
Sbjct: 315 EDTSHTSAQKAPE 327



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 30/130 (23%), Positives = 56/130 (43%), Gaps = 15/130 (11%)

Query: 86  EEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRESKGSSNIQETDE 145
           EE       +  EE+ +EE EE E+  ++  +             + E +     +E +E
Sbjct: 246 EESSKQKGILSHEEEDEEEEEEEEEEEEDEEE-------------EEEEEEEEEEEEEEE 292

Query: 146 E-DEEEEDDDDDDEGEDDGEESEETNREEEGKAKEQIRNCENNCQQVTDKAFKEQRDRPE 204
           E +EEEE++++++E   D    E+T+     KA E +R  E+   +       E R   +
Sbjct: 293 EEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPE-LRGPESPSPKPEYSVIVEVRSDDD 351

Query: 205 AQEQSEKKIS 214
             E +  + S
Sbjct: 352 KDEDTHSRKS 361



 Score = 29.6 bits (65), Expect = 7.7
 Identities = 34/175 (19%), Positives = 66/175 (37%), Gaps = 10/175 (5%)

Query: 2   SEHSRNSDQEELLDEEINEDEILANLSAEELKEL--QSEMEVMAPDPSLPVGMIQKDQTD 59
           +E + + + E+ L  +  + E +  ++ E  ++L  QS  +  + + S   G++  ++ D
Sbjct: 202 AEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEED 261

Query: 60  KPPTGNFNHKSLVDYMYWEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYL 119
           +        +        E+      EEE       + EE+ +EE EE E+         
Sbjct: 262 EEEEEEEEEE--------EEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIF 313

Query: 120 KEKLNNEIVANKRESKGSSNIQETDEEDEEEEDDDDDDEGEDDGEESEETNREEE 174
           +E  ++       E +G  +     E     E   DDD+ ED          E E
Sbjct: 314 QEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDEDTHSRKSTVTDESE 368


>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
          Length = 727

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 71/306 (23%), Positives = 126/306 (41%), Gaps = 51/306 (16%)

Query: 107 EIEKRNKNMAQYLKEKLNNEIVANKRE--SKGSSN------------IQETDEEDEE-EE 151
           E+++R    +Q  KE++N+E   +  E  S GSS+            ++E  EEDEE EE
Sbjct: 158 EVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEE 217

Query: 152 DDDDDDEGEDDGEESEETNREEEGKAKEQIRNCENNCQQVTDKAFKEQRDRPEAQEQSEK 211
           D ++D+E ++DGEE EE   EEE + +E+    E           +++RD+ E     + 
Sbjct: 218 DAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYE-----------QDERDQKEEGNDYDT 266

Query: 212 KISKLDPKKLALDTSFLKVSTRPSGNQTDLDGSLRRVRKNDPDMKELNLNNIENIPK--- 268
           +    D    ++  SF   S R SG+ TD     ++ RK    +  +  +   +      
Sbjct: 267 RSEASDSGSESV--SFTDGSVR-SGSGTDGSDEKKKERKRARGISPIVFDRSGSSASESY 323

Query: 269 -------EMLLDFVNAMKKNKHIK--------TFSLANVGADENVAFALANMLRENRSIT 313
                  E L   V A++K++  K         F L      ENV+ A A  +     + 
Sbjct: 324 AGSEKKHEKLSSSVRAVRKDQTSKLKYVLQDARFFLIKSNNHENVSLAKAKGVWSTLPVN 383

Query: 314 TLNIESNFITGKGIVAIMRCLQFNETLTELRFHNQRHMLGHHAEMEIARLLKANNTLLKM 373
              +   F + + ++ I    +  +     R  ++     HH    I  +L A  +   +
Sbjct: 384 EKKLNLAFRSARSVILIFSVRESGKFQGFARLSSE----SHHGGSPIHWVLPAGMSAKML 439

Query: 374 GYHFEL 379
           G  F++
Sbjct: 440 GGVFKI 445


>gi|115511012 coiled-coil domain containing 136 [Homo sapiens]
          Length = 1154

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 38/123 (30%), Positives = 66/123 (53%), Gaps = 14/123 (11%)

Query: 53   IQKDQTDKPPTGNFNHKSLVDYMYWEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRN 112
            + K  +D   +     KSL   +Y+ KAS+R L+             K +E+ EE+E+  
Sbjct: 999  VTKPCSDTSESDLETRKSLEVVLYY-KASQRKLD----------GLAKEEEKKEEMEEEK 1047

Query: 113  KNMAQYLKEKLNNEIV---ANKRESKGSSNIQETDEEDEEEEDDDDDDEGEDDGEESEET 169
            K + +  KE+  +E+V   A+  E+K + + +E +E+ EEEE ++D +E EDD + S E+
Sbjct: 1048 KQVKEEAKEQCGDELVAEPADPEEAKSTEDQEENEEDKEEEEKEEDSEEEEDDADSSLES 1107

Query: 170  NRE 172
              E
Sbjct: 1108 PEE 1110



 Score = 31.6 bits (70), Expect = 2.0
 Identities = 43/214 (20%), Positives = 86/214 (40%), Gaps = 39/214 (18%)

Query: 2   SEHSRN--SDQEEL--LDEEINEDEILANLSAEELKELQSEMEVMAPDPSLPVGMIQKDQ 57
           +EH  +  S QE+L  +  E+ + E +      E+  L++EME+ + +PS  +G      
Sbjct: 162 TEHESDIASLQEDLCRMQNELEDMERIRGDYEMEIASLRAEMEMKSSEPSGSLG------ 215

Query: 58  TDKPPTGNFNHKSLVDYMYWEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQ 117
                        L DY       +  L+E R    F+       EE+  +++ N ++  
Sbjct: 216 -------------LSDY----SGLQEELQELRERYHFLN------EEYRALQESNSSLTG 252

Query: 118 YLKEKLNNEIVANKRESKGSSNIQETDEEDEEEEDDDDDDEGEDDGEESEETNREEEGKA 177
            L +  +            S  +  T  E +  E D  + + E       +  R++   A
Sbjct: 253 QLADLESERTQRATERWLQSQTLSMTSAESQTSEMDFLEPDPE------MQLLRQQLRDA 306

Query: 178 KEQIRNCENNCQQVTDKAFKEQRDRPEAQEQSEK 211
           +EQ+   +N CQ++  +  + Q  R  ++E+  +
Sbjct: 307 EEQMHGMKNKCQELCCELEELQHHRQVSEEEQRR 340


>gi|115529449 upstream binding transcription factor, RNA polymerase
           I isoform b [Homo sapiens]
          Length = 727

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 46/217 (21%), Positives = 91/217 (41%), Gaps = 43/217 (19%)

Query: 28  SAEELKELQSEMEVMAPDPSL----------------PVGMIQKDQTDKPPTGNFNHKSL 71
           +AE+ K  + E+  M   P+                 P+   QK   +    G  NH  L
Sbjct: 497 AAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPL 556

Query: 72  VDYMY-----WEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNNE 126
            + M      W++ S+   E  +      + ++K  + H ++  ++ +       K   E
Sbjct: 557 KERMVEIGSRWQRISQSQKEHYK---KLAEEQQKQYKVHLDLWVKSLSPQDRAAYK---E 610

Query: 127 IVANKRES----------------KGSSNIQETDEEDEEEEDDDDDDEGEDDGEESEETN 170
            ++NKR+S                +  S  +E DEEDE++ED+D+++E +++G+ SE+  
Sbjct: 611 YISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGG 670

Query: 171 REEEGKAKEQIRNCENNCQQVTDKAFKEQRDRPEAQE 207
              E  ++++  + + N +   D+   E  D  E  E
Sbjct: 671 DSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNE 707



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 25/91 (27%), Positives = 46/91 (50%), Gaps = 3/91 (3%)

Query: 96  KSEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRESKG---SSNIQETDEEDEEEED 152
           KSE +  +E +E ++      +  +   ++E   +  ES     S +  E +E+DE+E+D
Sbjct: 637 KSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDD 696

Query: 153 DDDDDEGEDDGEESEETNREEEGKAKEQIRN 183
           D+DDDE ED+  E   ++    G + +   N
Sbjct: 697 DEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 25/97 (25%), Positives = 54/97 (55%), Gaps = 3/97 (3%)

Query: 93  TFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRESKGSSNIQETDEEDEEEED 152
           T ++S+ +++E+ EE E  +++  +  ++  N +   +  +S  SS+  E+++ DE EED
Sbjct: 632 TTLQSKSESEEDDEEDED-DEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEED 690

Query: 153 D--DDDDEGEDDGEESEETNREEEGKAKEQIRNCENN 187
           D  +DDDE +D+ E++E         +     + ++N
Sbjct: 691 DEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727


>gi|115529451 upstream binding transcription factor, RNA polymerase
           I isoform b [Homo sapiens]
          Length = 727

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 46/217 (21%), Positives = 91/217 (41%), Gaps = 43/217 (19%)

Query: 28  SAEELKELQSEMEVMAPDPSL----------------PVGMIQKDQTDKPPTGNFNHKSL 71
           +AE+ K  + E+  M   P+                 P+   QK   +    G  NH  L
Sbjct: 497 AAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPL 556

Query: 72  VDYMY-----WEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNNE 126
            + M      W++ S+   E  +      + ++K  + H ++  ++ +       K   E
Sbjct: 557 KERMVEIGSRWQRISQSQKEHYK---KLAEEQQKQYKVHLDLWVKSLSPQDRAAYK---E 610

Query: 127 IVANKRES----------------KGSSNIQETDEEDEEEEDDDDDDEGEDDGEESEETN 170
            ++NKR+S                +  S  +E DEEDE++ED+D+++E +++G+ SE+  
Sbjct: 611 YISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGG 670

Query: 171 REEEGKAKEQIRNCENNCQQVTDKAFKEQRDRPEAQE 207
              E  ++++  + + N +   D+   E  D  E  E
Sbjct: 671 DSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNE 707



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 25/91 (27%), Positives = 46/91 (50%), Gaps = 3/91 (3%)

Query: 96  KSEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRESKG---SSNIQETDEEDEEEED 152
           KSE +  +E +E ++      +  +   ++E   +  ES     S +  E +E+DE+E+D
Sbjct: 637 KSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDD 696

Query: 153 DDDDDEGEDDGEESEETNREEEGKAKEQIRN 183
           D+DDDE ED+  E   ++    G + +   N
Sbjct: 697 DEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 25/97 (25%), Positives = 54/97 (55%), Gaps = 3/97 (3%)

Query: 93  TFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRESKGSSNIQETDEEDEEEED 152
           T ++S+ +++E+ EE E  +++  +  ++  N +   +  +S  SS+  E+++ DE EED
Sbjct: 632 TTLQSKSESEEDDEEDED-DEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEED 690

Query: 153 D--DDDDEGEDDGEESEETNREEEGKAKEQIRNCENN 187
           D  +DDDE +D+ E++E         +     + ++N
Sbjct: 691 DEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727


>gi|7657671 upstream binding transcription factor, RNA polymerase I
           isoform a [Homo sapiens]
          Length = 764

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 46/217 (21%), Positives = 91/217 (41%), Gaps = 43/217 (19%)

Query: 28  SAEELKELQSEMEVMAPDPSL----------------PVGMIQKDQTDKPPTGNFNHKSL 71
           +AE+ K  + E+  M   P+                 P+   QK   +    G  NH  L
Sbjct: 534 AAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPL 593

Query: 72  VDYMY-----WEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNNE 126
            + M      W++ S+   E  +      + ++K  + H ++  ++ +       K   E
Sbjct: 594 KERMVEIGSRWQRISQSQKEHYK---KLAEEQQKQYKVHLDLWVKSLSPQDRAAYK---E 647

Query: 127 IVANKRES----------------KGSSNIQETDEEDEEEEDDDDDDEGEDDGEESEETN 170
            ++NKR+S                +  S  +E DEEDE++ED+D+++E +++G+ SE+  
Sbjct: 648 YISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGG 707

Query: 171 REEEGKAKEQIRNCENNCQQVTDKAFKEQRDRPEAQE 207
              E  ++++  + + N +   D+   E  D  E  E
Sbjct: 708 DSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNE 744



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 25/91 (27%), Positives = 46/91 (50%), Gaps = 3/91 (3%)

Query: 96  KSEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRESKG---SSNIQETDEEDEEEED 152
           KSE +  +E +E ++      +  +   ++E   +  ES     S +  E +E+DE+E+D
Sbjct: 674 KSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDD 733

Query: 153 DDDDDEGEDDGEESEETNREEEGKAKEQIRN 183
           D+DDDE ED+  E   ++    G + +   N
Sbjct: 734 DEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 25/97 (25%), Positives = 54/97 (55%), Gaps = 3/97 (3%)

Query: 93  TFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRESKGSSNIQETDEEDEEEED 152
           T ++S+ +++E+ EE E  +++  +  ++  N +   +  +S  SS+  E+++ DE EED
Sbjct: 669 TTLQSKSESEEDDEEDED-DEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEED 727

Query: 153 D--DDDDEGEDDGEESEETNREEEGKAKEQIRNCENN 187
           D  +DDDE +D+ E++E         +     + ++N
Sbjct: 728 DEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 35/140 (25%), Positives = 74/140 (52%), Gaps = 3/140 (2%)

Query: 85   LEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRES--KGSSNIQE 142
            +EEE V + F+K   + ++E +  +K  +  +  + E  + E  + + ES        + 
Sbjct: 2184 IEEEEV-IPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQES 2242

Query: 143  TDEEDEEEEDDDDDDEGEDDGEESEETNREEEGKAKEQIRNCENNCQQVTDKAFKEQRDR 202
               E+EEE +++++ E E+  EE EE   EEEG+ K+  +  E   ++  +K  +E +++
Sbjct: 2243 LSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEK 2302

Query: 203  PEAQEQSEKKISKLDPKKLA 222
             E  E+ E+ +S+ + + L+
Sbjct: 2303 EEVFEEKEEIMSEEETESLS 2322



 Score = 52.8 bits (125), Expect = 8e-07
 Identities = 56/213 (26%), Positives = 93/213 (43%), Gaps = 22/213 (10%)

Query: 11   EELLDEE----INEDEILANLSAEELKELQSEMEVMAPDPSLPVGMIQKDQTDKPPTGNF 66
            E +LD+E    I E+E++  L     +  +   E    D        Q D+ +     + 
Sbjct: 2173 EVILDDEEEGGIEEEEVIPFLK----RRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSE 2228

Query: 67   NHKSLVDYMYWEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNNE 126
              +SL+D +  +++     EEER      + EE  +EE E  E+      Q  KE+   E
Sbjct: 2229 EMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEE---E 2285

Query: 127  IVANKRESKGSSNIQETDEEDEEEEDDDDDDEGE---DDGEESEETNREEEGKAKEQIRN 183
                K++ K    +QE +E  EE+E+   ++E E   D+ EE E  + EEE   +++I  
Sbjct: 2286 EKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILK 2345

Query: 184  CENNCQQVTDKAFKEQRDRPEAQEQSEKKISKL 216
             E        K FK Q  R ++    E+ +S L
Sbjct: 2346 KE--------KQFKLQEQRRKSLRGRERVLSIL 2370



 Score = 42.7 bits (99), Expect = 9e-04
 Identities = 47/222 (21%), Positives = 91/222 (40%), Gaps = 30/222 (13%)

Query: 9    DQEELLDEEINEDEILANLSAEE--LKELQSEMEVMAPDPSLPVGMIQKDQTDKPPTGNF 66
            D+ +L  EEI   ++   L  +E  L   QS++++   D S     + KD+         
Sbjct: 2086 DERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLAR---- 2141

Query: 67   NHKSLVDYMYWEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEK--------RNKNMAQY 118
              + L + M      RRM+ +E       + E K   +H E+            + +  +
Sbjct: 2142 KQRKLANKM------RRMINKEE---KMTEEESKLARKHSEVILDDEEEGGIEEEEVIPF 2192

Query: 119  LKEKLNNEIVANKRESKGSSNIQETDEEDEEEEDDDDDDEGEDDGEESEETNREEEGKAK 178
            LK +      A + +        + DE + EE   ++ +   D+ E+ E  + EEE + +
Sbjct: 2193 LKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEERE 2252

Query: 179  EQIRNCENNCQQVTDKAFKEQRDRPEAQEQSEKKISKLDPKK 220
            E+    E   ++       E+ +R E +E  EK++ K + +K
Sbjct: 2253 EEEEREEEEVRE-------EEEERKEEEEGEEKQVEKEEEEK 2287



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 49/218 (22%), Positives = 94/218 (43%), Gaps = 21/218 (9%)

Query: 27   LSAEELKELQSEMEVMAPDPSLPVGMIQKDQTDKPPT---GNFNHKSLVDYMYWEKASRR 83
            L+ EE K  Q E ++   +  L    ++  Q D+      G F  K        EK S+ 
Sbjct: 1595 LAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQE 1654

Query: 84   MLEEERVPVTFVKSEEKTQEEHEEIEKRN------KN-MAQYLKEKLNNEIVANKRESKG 136
              +  +      K  EK   E E++ K+       KN +AQ ++E    E   + +E + 
Sbjct: 1655 AEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKEL 1714

Query: 137  SSNIQETDEEDEE---EEDDDDDDEGE--------DDGEESEETNREEEGKAKEQIRNCE 185
            +  ++E + + EE   +E++ + +EG+         + EE+    RE+  + + ++   E
Sbjct: 1715 AQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEE 1774

Query: 186  NNCQQVTDKAFKEQRDRPEAQEQSEKKISKLDPKKLAL 223
                Q  +K  + +   PE +E+  +K  +L  KK+ L
Sbjct: 1775 ELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKL 1812



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 29/148 (19%), Positives = 70/148 (47%), Gaps = 12/148 (8%)

Query: 76   YWEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRESK 135
            ++ +    +L+E     +    EE+ +EE EE E+          E++  E    K E +
Sbjct: 2225 HFSEEMESLLDELEKQESLSSEEEEEREEEEEREE----------EEVREEEEERKEEEE 2274

Query: 136  GSSNIQETDEEDEEEEDDDDDDEGEDDGEESEETNREEEGKAKEQIRNCENNCQQVTDKA 195
            G    ++ ++E+EE++    + + E+  E+ E    +EE  ++E+  +  +  ++    +
Sbjct: 2275 GEE--KQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCS 2332

Query: 196  FKEQRDRPEAQEQSEKKISKLDPKKLAL 223
             +E+ DR +   + EK+    + ++ +L
Sbjct: 2333 LEEEVDREKEILKKEKQFKLQEQRRKSL 2360



 Score = 36.2 bits (82), Expect = 0.082
 Identities = 35/151 (23%), Positives = 73/151 (48%), Gaps = 23/151 (15%)

Query: 77   WEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRESKG 136
            WEK   R+L+EE       ++ EK   E E +++  K   +  K+   N + +  +E   
Sbjct: 1485 WEK---RLLQEEE---KLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKE--- 1535

Query: 137  SSNIQETDEEDEEEEDDDDDDEGEDDGEESEETNREEEGKAKEQIRNCENNCQQVTDKAF 196
                    ++ ++EE+   ++E   +GEE E+   EE+   +E+ +    + ++   +  
Sbjct: 1536 --------QQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKK 1587

Query: 197  KEQRDRPEAQE-----QSEKKISKLDPKKLA 222
            + Q +R  AQE     Q E+++++ + +KLA
Sbjct: 1588 RAQEERKLAQEEEKLAQEERQLAQ-EERKLA 1617


>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
          Length = 1184

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 38/155 (24%), Positives = 80/155 (51%), Gaps = 11/155 (7%)

Query: 98  EEKTQEEH-EEIEKRNKNMAQYLKEKLNNEIVANKRESKGSSNIQETDEEDEEEEDDDDD 156
           + KTQ++  +E   + K  A     K ++  V    +S G+ ++ E +E++ EE  +D+D
Sbjct: 60  KRKTQDKQPQEPAPKRKPFAV----KADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDND 115

Query: 157 DEGEDDGEESEETNREEEGKAKEQIRNCENNCQQVTDKAFKEQRDRPEAQEQSEKKISKL 216
           + G++D EE EE +REEE + +E+  + + + + V D+  +E+ +  E +E+  +     
Sbjct: 116 EPGDED-EEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENE----- 169

Query: 217 DPKKLALDTSFLKVSTRPSGNQTDLDGSLRRVRKN 251
           D +    +T  ++ + +   N  + D     V K+
Sbjct: 170 DHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAKS 204



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 35/141 (24%), Positives = 68/141 (48%), Gaps = 13/141 (9%)

Query: 141 QETDEEDEEEED---DDDDDEGEDDGEESEETNREEEGKAKEQIRNCENNCQQVTDKAFK 197
           +E D E+EEE +   +DDD++GED  +E EE   EEE + +E+  + + NC         
Sbjct: 125 EEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDT 184

Query: 198 EQRDRPEAQEQSEKKI---SKLDPKKLALDTSFLKVSTRPSGNQTDLDGSLRRVRKNDPD 254
           E+ D    +  +  ++   S L+  K+A D ++       +  +++++ +     ++D D
Sbjct: 185 EKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAY------RARTESEMNSNTSNSLEDDSD 238

Query: 255 MKELNLNNIENIPKEMLLDFV 275
             E NL     +  ++  D V
Sbjct: 239 KNE-NLGRKSELSLDLDSDVV 258



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 24/87 (27%), Positives = 41/87 (47%), Gaps = 19/87 (21%)

Query: 96  KSEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRESKGSSNIQETDEEDEEEEDDDD 155
           + EE  +EE EEIE+ +++      +  + E V ++ E +     +E +EE+EEE +D  
Sbjct: 123 EDEEGDREEEEEIEEEDED------DDEDGEDVEDEEEEEE----EEEEEEEEEENEDHQ 172

Query: 156 ---------DDEGEDDGEESEETNREE 173
                     D  +DD    E  N +E
Sbjct: 173 MNCHNTRIMQDTEKDDNNNDEYDNYDE 199



 Score = 29.6 bits (65), Expect = 7.7
 Identities = 26/100 (26%), Positives = 44/100 (44%), Gaps = 20/100 (20%)

Query: 95  VKSEEKTQEEHEEIEKRNKN------------MAQYLKEKLNNEIVANKRE--SKGSSNI 140
           V+ EE+ +EE EE E+  +N            M    K+  NN+   N  E  +K   N+
Sbjct: 149 VEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLLNL 208

Query: 141 QETDEE------DEEEEDDDDDDEGEDDGEESEETNREEE 174
            +  E+       E E + +  +  EDD +++E   R+ E
Sbjct: 209 GKIAEDAAYRARTESEMNSNTSNSLEDDSDKNENLGRKSE 248


>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
          Length = 732

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 39/161 (24%), Positives = 80/161 (49%), Gaps = 14/161 (8%)

Query: 99  EKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRESKGSSNIQETDEEDEEEEDDDDDDE 158
           +K QEE E +EK  +       ++L  E +  K E +    ++E   + EEE    ++++
Sbjct: 414 QKEQEEQERVEKEEQ-------DRLEREELKRKAEEE-RLRLEEEARKQEEERKRQEEEK 465

Query: 159 GEDDGEESEETNREEEGKAKEQIRNCENNCQQVTDKAFKEQRDRPEAQEQSEKKISKLDP 218
            + +GEE  +   E + KA+E++   E   Q+  +KA  E+  + EA E   ++++  + 
Sbjct: 466 KKQEGEEKRKAGEEAKRKAEEELLLKEKQEQEKQEKAMIEK--QKEAAETKAREVA--EQ 521

Query: 219 KKLALDTSFLKVSTRPSGNQTDLDGSLRRVRKND--PDMKE 257
            +L  +   L++       +  +D  ++R RK+D  P +K+
Sbjct: 522 MRLEREQIMLQIEQERLERKKRIDEIMKRTRKSDVPPQVKK 562



 Score = 29.6 bits (65), Expect = 7.7
 Identities = 24/98 (24%), Positives = 47/98 (47%), Gaps = 4/98 (4%)

Query: 94  FVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRESKGSSNIQETDEEDEEEEDD 153
           F+KS+E+ +   E  E+R K +A   ++ L  +  A  +  K    ++E   + EE+   
Sbjct: 48  FLKSDERQRLAKERREEREKCLAAREQQILEKQKRARLQYEK---QMEERWRKLEEQRQR 104

Query: 154 DDDDEGEDDGEESEETNREEEGKAKEQIRNCENNCQQV 191
           +D      + E+ ++  REEE + +  +R      QQ+
Sbjct: 105 EDQKRAAVE-EKRKQKLREEEERLEAMMRRSLERTQQL 141


>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
          Length = 1670

 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 78/373 (20%), Positives = 158/373 (42%), Gaps = 37/373 (9%)

Query: 53  IQKDQTDKPPTGNFNHKSLVDY----MYWEKASRRMLEEERVPVTFVKSEEKTQEEHEEI 108
           +Q+++  K     F  K   +Y    M  EK  + ++E+++      ++E K Q+E EE 
Sbjct: 350 MQEEEPQKKLPVTFEDKRKANYERGNMELEKRRQALMEQQQR-----EAERKAQKEKEEW 404

Query: 109 EKRNKNMAQYLKEKLNNEIVANKRESKGSSNIQETDEEDEEEEDDDDDDEGEDDGEESEE 168
           E++ + + +   ++   ++   KR  K     Q   E   EEE   D +  E   +E E 
Sbjct: 405 ERKQRELQE---QEWKKQLELEKRLEK-----QRELERQREEERRKDIERREAAKQELER 456

Query: 169 TNREE-EGKAKEQIRNCENNCQQVTDKAFKEQRD---RPEAQEQSEKKIS-KLDPKKLAL 223
             R E E   ++++ N +N  Q+   +   ++++     EA     ++IS +L   +L  
Sbjct: 457 QRRLEWERIRRQELLNQKNREQEEIVRLNSKKKNLHLELEALNGKHQQISGRLQDVRLKK 516

Query: 224 DTSFLKVSTRPSGNQTDLDGSLRRVRKNDPDMKELNLNNIENIPKEMLLDFVNAMKKNKH 283
            T   K        Q DL+  +  +++   +++E     I  +P++ LL        N+ 
Sbjct: 517 QTQ--KTELEVLDKQCDLE--IMEIKQLQQELQEYQNKLIYLVPEKQLL--------NER 564

Query: 284 IKTFSLANVGADENVAFALANMLRENRSITTLNIESNFITGKGIVAIMRCLQFNETLTEL 343
           IK    +N   D  V+      L +      L  + + +  +    +     FN  L EL
Sbjct: 565 IKNMQFSNT-PDSGVSLLHKKSLEKEELCQRLKEQLDALEKETASKLSEMDSFNNQLKEL 623

Query: 344 R--FHNQRHMLGHHAEMEIARLLKANNTLLKMGYHFELPGPRMVVTNLLTRNQDKQRQKR 401
           R  ++ Q+  L    +++  +L +     L++    +L             N  K+  ++
Sbjct: 624 RETYNTQQLALEQLYKIKRDKLKEIERKRLELMQKKKLEDEAARKAKQGKENLWKENLRK 683

Query: 402 QEEQKQQQLKEQK 414
           +EE+KQ++L+E+K
Sbjct: 684 EEEEKQKRLQEEK 696



 Score = 35.0 bits (79), Expect = 0.18
 Identities = 42/212 (19%), Positives = 92/212 (43%), Gaps = 21/212 (9%)

Query: 12  ELLDEEINEDEILANLSAEELKELQSEMEVMAPDPSLPVGMIQKDQTDKPPTGNFN--HK 69
           E+LD++ + + +      +EL+E Q+++  + P+  L    I+  Q    P    +  HK
Sbjct: 524 EVLDKQCDLEIMEIKQLQQELQEYQNKLIYLVPEKQLLNERIKNMQFSNTPDSGVSLLHK 583

Query: 70  SLVDYMYWEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVA 129
             ++    E+  +R+ E+          E++T  +  E++  N N  + L+E  N + +A
Sbjct: 584 KSLEK---EELCQRLKEQ------LDALEKETASKLSEMDSFN-NQLKELRETYNTQQLA 633

Query: 130 ---------NKRESKGSSNIQETDEEDEEEEDDDDDDEGEDDGEESEETNREEEGKAKEQ 180
                    +K +      ++   ++  E+E      +G+++  +      EEE + + Q
Sbjct: 634 LEQLYKIKRDKLKEIERKRLELMQKKKLEDEAARKAKQGKENLWKENLRKEEEEKQKRLQ 693

Query: 181 IRNCENNCQQVTDKAFKEQRDRPEAQEQSEKK 212
               +   Q+   KA ++QR   +  +  EKK
Sbjct: 694 EEKTQEKIQEEERKAEEKQRKDKDTLKAEEKK 725


>gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens]
          Length = 1312

 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 43/200 (21%), Positives = 102/200 (51%), Gaps = 27/200 (13%)

Query: 11  EELLDEEINEDEILANLSAEE-----LKELQSEMEV-MAPDPSLPV-GMIQKDQTDKPPT 63
           E++++++  E E +  +  +E     +KE++ E E  + P    P+   I++ +  KP  
Sbjct: 410 EKVVNKQCKECENVKEIKVKEENETEIKEIKMEEERNIIPREEKPIEDEIERKENIKPSL 469

Query: 64  GNFNHKSLVDYMYWEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKL 123
           G+   K+L+     E       +E+ V +       K  E++E ++ ++ +  + + E L
Sbjct: 470 GS--KKNLL-----ESIPTHSDQEKEVNI-------KKPEDNENLDDKDDDTTR-VDESL 514

Query: 124 NNEIVANKRESKGSSNIQETDEEDEEEEDDDDDDEGEDDGEESEETNREEEGKA-----K 178
           N ++ A + ++K      + ++ED+EE ++++++E E++ E+ ++ N EEE +      K
Sbjct: 515 NIKVEAEEEKAKSGDETNKEEDEDDEEAEEEEEEEEEEEDEDDDDNNEEEEFECYPPGMK 574

Query: 179 EQIRNCENNCQQVTDKAFKE 198
            Q+R      Q++ + + K+
Sbjct: 575 VQVRYGRGKNQKMYEASIKD 594



 Score = 36.6 bits (83), Expect = 0.063
 Identities = 36/150 (24%), Positives = 68/150 (45%), Gaps = 13/150 (8%)

Query: 85  LEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRESKGSSNIQETD 144
           +EEER     +  EEK  E+  EIE++       +K  L ++   N  ES  + + QE +
Sbjct: 441 MEEER---NIIPREEKPIED--EIERKEN-----IKPSLGSK--KNLLESIPTHSDQEKE 488

Query: 145 EEDEEEEDDDD-DDEGEDDGEESEETNREEEGKAKEQIRNCENNCQQVTDKAFKEQRDRP 203
              ++ ED+++ DD+ +D     E  N + E + ++     E N ++  D    E+ +  
Sbjct: 489 VNIKKPEDNENLDDKDDDTTRVDESLNIKVEAEEEKAKSGDETNKEEDEDDEEAEEEEEE 548

Query: 204 EAQEQSEKKISKLDPKKLALDTSFLKVSTR 233
           E +E+ E      + ++       +KV  R
Sbjct: 549 EEEEEDEDDDDNNEEEEFECYPPGMKVQVR 578



 Score = 36.2 bits (82), Expect = 0.082
 Identities = 22/66 (33%), Positives = 35/66 (53%), Gaps = 1/66 (1%)

Query: 117 QYLKEKLNNEIVAN-KRESKGSSNIQETDEEDEEEEDDDDDDEGEDDGEESEETNREEEG 175
           Q L+   +  I AN K E K  S+  E +EE+EEE+D+ + ++   + EE  E   EE  
Sbjct: 251 QALEFHKSRTIPANWKTELKEDSSSSEAEEEEEEEDDEKEKEDNSSEEEEEIEPFPEERE 310

Query: 176 KAKEQI 181
              +Q+
Sbjct: 311 NFLQQL 316



 Score = 34.3 bits (77), Expect = 0.31
 Identities = 19/59 (32%), Positives = 31/59 (52%), Gaps = 2/59 (3%)

Query: 145 EEDEEEEDDDDDDEGEDDGEESEETNREEEGKAKEQIRNCENNCQQVTDKAFKEQRDRP 203
           +ED    + ++++E EDD +E E+ + EEE + +      EN  QQ+    F E R  P
Sbjct: 270 KEDSSSSEAEEEEEEEDDEKEKEDNSSEEEEEIEPFPEERENFLQQL--YKFMEDRGTP 326



 Score = 29.6 bits (65), Expect = 7.7
 Identities = 48/246 (19%), Positives = 85/246 (34%), Gaps = 42/246 (17%)

Query: 5   SRNSDQEELLDEEINEDEILANLSAEELKELQSEMEVMAPDPSLPVGMIQKDQTDKPPTG 64
           ++NSD   +   EI    IL  L A E     SE E       +     ++ + D     
Sbjct: 687 AKNSDTAHIKSIEITS--ILNGLQASESSAEDSEQEDERGAQDMDNNGKEESKIDHLTN- 743

Query: 65  NFNHKSLVDYMYWEKASRRMLEEERVPVTFVKSE-----------------EKTQEEHEE 107
             N   L+     E+ S  +LEE +V    V S+                 E T  E +E
Sbjct: 744 --NRNDLISKE--EQNSSSLLEENKVHADLVISKPVSKSPERLRKDIEVLSEDTDYEEDE 799

Query: 108 IEKRNKNMAQYLKEKLNNEIVAN------------------KRESKGSSNIQETDEEDEE 149
           + K+ K++ +   +K +   +                    K+E K  +      E    
Sbjct: 800 VTKKRKDVKKDTTDKSSKPQIKRGKRRYCNTEECLKTGSPGKKEEKAKNKESLCMENSSN 859

Query: 150 EEDDDDDDEGEDDGEESEETNREEEGKAKEQIRNCENNCQQVTDKAFKEQRDRPEAQEQS 209
              D+D++E +     +++ N  EE +   +     +   +V +K  K   +  E  + S
Sbjct: 860 SSSDEDEEETKAKMTPTKKYNGLEEKRKSLRTTGFYSGFSEVAEKRIKLLNNSDERLQNS 919

Query: 210 EKKISK 215
             K  K
Sbjct: 920 RAKDRK 925


>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
          Length = 2454

 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 33/130 (25%), Positives = 67/130 (51%), Gaps = 12/130 (9%)

Query: 97   SEEKTQEEHEEIEKRN--------KNMAQYLKEKLNNEIVANKRESKGSSNIQETDEEDE 148
            SEE ++ E E+  +          +N   Y ++K    I   +  S  + +  E +EE++
Sbjct: 1352 SEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEK 1411

Query: 149  EEEDDDDDDEGEDDGEESEETNREEEGKAKEQIRNC--ENNCQQVTDKAFKEQRDRPEAQ 206
            EEE++++++E E+  EE E  + +  GK +++IR    ++  +  T  A KE+ +R +  
Sbjct: 1412 EEEEEEEEEEEEE--EEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRI 1469

Query: 207  EQSEKKISKL 216
             + E++  KL
Sbjct: 1470 AEREREREKL 1479



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 48/218 (22%), Positives = 97/218 (44%), Gaps = 15/218 (6%)

Query: 7    NSDQEELLDEEINEDEILANLSAEELKELQSEMEVMAPDPSLPVGMIQKDQT-DKPPTGN 65
            ++D E  + +++  +EI ANLS++E      E E    +     G   ++   D+     
Sbjct: 1226 DNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPE----EGKKRTGKQNEENPGDEEAKNQ 1281

Query: 66   FNHKSLVDYMYWEKAS-RRMLEEERVPVTFVKS--EEKTQ-EEHEEIEKRNKNMAQYLKE 121
             N +S  D    +K   R  L   ++ V+  +S  E+KT+ +EH+E++ RN+      K 
Sbjct: 1282 VNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRR-----KV 1336

Query: 122  KLNNEIVANKRESKGSSNIQETDEEDEEEEDDDDDDEGEDDGEESEETNREEEGKAKEQI 181
               +   ++ +ES  S  + E+++E           E E++    ++  +    K +E  
Sbjct: 1337 SSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQED- 1395

Query: 182  RNCENNCQQVTDKAFKEQRDRPEAQEQSEKKISKLDPK 219
             + EN      ++  KE+ +  E +E+ E++    D K
Sbjct: 1396 SSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSK 1433



 Score = 37.0 bits (84), Expect = 0.048
 Identities = 44/230 (19%), Positives = 92/230 (40%), Gaps = 15/230 (6%)

Query: 8   SDQEELLDEEINEDEILANLS--AEELKELQSEMEVMAPDPSLPVGMIQKDQTDKPPTGN 65
           S Q E +D+  + DE+LA L   +       S+ ++     +       K Q  K   G 
Sbjct: 681 SKQSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGK 740

Query: 66  FNHKSLVDYMYWEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNN 125
              KS      ++    +  +   +     +++ ++     E+EK  K+M++    +   
Sbjct: 741 RKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTK 800

Query: 126 EIVANKRESKGSSNIQETDEEDEEEEDDDDDDEGEDDGEESEETNREEEGKAKEQIRNCE 185
           + + N ++   S        EDE+      D++G  + + S+E + ++  + +E  R   
Sbjct: 801 KRIPNTKDFDSS--------EDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQE--RETF 850

Query: 186 NNCQQVTDK--AFKEQRDRPEAQEQSEKKISKLDPKKLALDTSFLKVSTR 233
           ++ +   DK     E RDR   ++Q+      +D K    + SF  +  R
Sbjct: 851 SSAEGTVDKDTTIMELRDRLPKKQQASASTDGVD-KLSGKEQSFTSLEVR 899



 Score = 33.1 bits (74), Expect = 0.69
 Identities = 35/172 (20%), Positives = 67/172 (38%), Gaps = 11/172 (6%)

Query: 101  TQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRES--KGSSNIQETDEEDEEEEDDDDDDE 158
            +  + EE  + NK   Q    K    IV  K+ +  + S+  ++ D       D +DDD+
Sbjct: 1116 SSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQ 1175

Query: 159  ---GEDDGEESEETNREEEGKAKEQIRNCENNCQQVTDKAFKEQRDRPEAQEQSEKKISK 215
               GE   +E +     E          C+++  +   K+     D  +     E +I+ 
Sbjct: 1176 NSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIA- 1234

Query: 216  LDPKKLALDTSFLKVSTRPSGNQTD--LDGSLRRVRKNDPDMKELNLNNIEN 265
               KK+ L+     +S+   G+  D   +G  R  ++N+ +  +    N  N
Sbjct: 1235 ---KKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVN 1283


>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
          Length = 2492

 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 33/130 (25%), Positives = 67/130 (51%), Gaps = 12/130 (9%)

Query: 97   SEEKTQEEHEEIEKRN--------KNMAQYLKEKLNNEIVANKRESKGSSNIQETDEEDE 148
            SEE ++ E E+  +          +N   Y ++K    I   +  S  + +  E +EE++
Sbjct: 1390 SEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEK 1449

Query: 149  EEEDDDDDDEGEDDGEESEETNREEEGKAKEQIRNC--ENNCQQVTDKAFKEQRDRPEAQ 206
            EEE++++++E E+  EE E  + +  GK +++IR    ++  +  T  A KE+ +R +  
Sbjct: 1450 EEEEEEEEEEEEE--EEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRI 1507

Query: 207  EQSEKKISKL 216
             + E++  KL
Sbjct: 1508 AEREREREKL 1517



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 48/218 (22%), Positives = 97/218 (44%), Gaps = 15/218 (6%)

Query: 7    NSDQEELLDEEINEDEILANLSAEELKELQSEMEVMAPDPSLPVGMIQKDQT-DKPPTGN 65
            ++D E  + +++  +EI ANLS++E      E E    +     G   ++   D+     
Sbjct: 1264 DNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPE----EGKKRTGKQNEENPGDEEAKNQ 1319

Query: 66   FNHKSLVDYMYWEKAS-RRMLEEERVPVTFVKS--EEKTQ-EEHEEIEKRNKNMAQYLKE 121
             N +S  D    +K   R  L   ++ V+  +S  E+KT+ +EH+E++ RN+      K 
Sbjct: 1320 VNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRR-----KV 1374

Query: 122  KLNNEIVANKRESKGSSNIQETDEEDEEEEDDDDDDEGEDDGEESEETNREEEGKAKEQI 181
               +   ++ +ES  S  + E+++E           E E++    ++  +    K +E  
Sbjct: 1375 SSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQED- 1433

Query: 182  RNCENNCQQVTDKAFKEQRDRPEAQEQSEKKISKLDPK 219
             + EN      ++  KE+ +  E +E+ E++    D K
Sbjct: 1434 SSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSK 1471



 Score = 37.0 bits (84), Expect = 0.048
 Identities = 44/230 (19%), Positives = 92/230 (40%), Gaps = 15/230 (6%)

Query: 8   SDQEELLDEEINEDEILANLS--AEELKELQSEMEVMAPDPSLPVGMIQKDQTDKPPTGN 65
           S Q E +D+  + DE+LA L   +       S+ ++     +       K Q  K   G 
Sbjct: 719 SKQSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGK 778

Query: 66  FNHKSLVDYMYWEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNN 125
              KS      ++    +  +   +     +++ ++     E+EK  K+M++    +   
Sbjct: 779 RKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTK 838

Query: 126 EIVANKRESKGSSNIQETDEEDEEEEDDDDDDEGEDDGEESEETNREEEGKAKEQIRNCE 185
           + + N ++   S        EDE+      D++G  + + S+E + ++  + +E  R   
Sbjct: 839 KRIPNTKDFDSS--------EDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQE--RETF 888

Query: 186 NNCQQVTDK--AFKEQRDRPEAQEQSEKKISKLDPKKLALDTSFLKVSTR 233
           ++ +   DK     E RDR   ++Q+      +D K    + SF  +  R
Sbjct: 889 SSAEGTVDKDTTIMELRDRLPKKQQASASTDGVD-KLSGKEQSFTSLEVR 937



 Score = 33.1 bits (74), Expect = 0.69
 Identities = 35/172 (20%), Positives = 67/172 (38%), Gaps = 11/172 (6%)

Query: 101  TQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRES--KGSSNIQETDEEDEEEEDDDDDDE 158
            +  + EE  + NK   Q    K    IV  K+ +  + S+  ++ D       D +DDD+
Sbjct: 1154 SSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQ 1213

Query: 159  ---GEDDGEESEETNREEEGKAKEQIRNCENNCQQVTDKAFKEQRDRPEAQEQSEKKISK 215
               GE   +E +     E          C+++  +   K+     D  +     E +I+ 
Sbjct: 1214 NSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIA- 1272

Query: 216  LDPKKLALDTSFLKVSTRPSGNQTD--LDGSLRRVRKNDPDMKELNLNNIEN 265
               KK+ L+     +S+   G+  D   +G  R  ++N+ +  +    N  N
Sbjct: 1273 ---KKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVN 1321


>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 436

 Score = 52.8 bits (125), Expect = 8e-07
 Identities = 32/130 (24%), Positives = 67/130 (51%), Gaps = 7/130 (5%)

Query: 86  EEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRESKGSSNIQETDE 145
           +EE+V     K EE+ Q++ E++ K+ + M +  ++    E    K++ +     Q  ++
Sbjct: 239 QEEQVQ----KQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQ 294

Query: 146 EDEEEEDDDDDDEGEDDGEESEETNREEE---GKAKEQIRNCENNCQQVTDKAFKEQRDR 202
           E++  E ++   E E+   E EE  RE+E   GK +EQ+   +    +  ++ +K++   
Sbjct: 295 EEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQM 354

Query: 203 PEAQEQSEKK 212
            E +EQ +K+
Sbjct: 355 GEQEEQMQKQ 364



 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 30/131 (22%), Positives = 64/131 (48%), Gaps = 7/131 (5%)

Query: 78  EKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRESKGS 137
           +K   +M E+E       K EE+  E+ E+++K+ + + +  ++    E    ++E +  
Sbjct: 216 QKQEEQMGEQEE---QMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMR 272

Query: 138 SNIQETDEEDEEEEDDDDDDEGEDDGEESEETNREEEGKAKEQIRNCENNCQQVTDKAFK 197
              ++  ++ E+ E ++   E E+   E EE  RE+E    EQ+R  E   ++  ++  K
Sbjct: 273 EQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQE----EQMREQEEQMREQEEQMGK 328

Query: 198 EQRDRPEAQEQ 208
           ++    E +EQ
Sbjct: 329 QEEQMWEQKEQ 339



 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 33/166 (19%), Positives = 77/166 (46%), Gaps = 9/166 (5%)

Query: 96  KSEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRESKGSSNIQETDEEDEEEEDDDD 155
           K EE+  E+ E++ K+ + M +  ++    E    K+E +         EE   E+++  
Sbjct: 217 KQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQ-----MRKQEEQMREQEEQM 271

Query: 156 DDEGEDDGEESEETNREEE-GKAKEQIRNCENNCQQVTDKAFKEQRDRPEAQEQSEKKIS 214
            ++ E   ++ E+T +EE+ G+ +EQ+R  E   ++  ++  +++    E +EQ  K+  
Sbjct: 272 REQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEE 331

Query: 215 KLDPKKLAL---DTSFLKVSTRPSGNQTDLDGSLRRVRKNDPDMKE 257
           ++  +K  +        K   +    +  +     +VRK +  M++
Sbjct: 332 QMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRK 377



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 37/181 (20%), Positives = 80/181 (44%), Gaps = 17/181 (9%)

Query: 3   EHSRNSDQEELLDEEINEDEILANLSAEELKELQSEMEVMAPDPSLPVGMI--QKDQTDK 60
           E  R  +++ L  +E  E E       E+++E + +M             +  Q++Q  K
Sbjct: 269 EQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGK 328

Query: 61  PPTGNFNHKSLVDYMYWEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLK 120
                +  K  +    WE+  +   +EE++     + EE+ Q++ E++ K+ + M +  +
Sbjct: 329 QEEQMWEQKEQM----WEQKEQMWKQEEQMG----EQEEQMQKQEEQVRKQEEQMRKQEE 380

Query: 121 EKLNNEIVANKRESKGSSNIQETDEEDEEEEDDDDDDEGEDDGEESEETNREEE--GKAK 178
           +    E    K+E +     ++  E+ E+  + +     E  GE+ E+  ++EE  G+ K
Sbjct: 381 QMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQE-----EQMGEQKEQMRKQEEHMGEQK 435

Query: 179 E 179
           E
Sbjct: 436 E 436



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 38/217 (17%), Positives = 89/217 (41%), Gaps = 11/217 (5%)

Query: 15  DEEINEDEILANLSAEELKELQSEMEVMAPDPSLPVGMIQKDQTDKPPTGNFNHKSLVDY 74
           +E++ E E       E++ E + +M             +QK +           K     
Sbjct: 205 EEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQM 264

Query: 75  MYWEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRES 134
              E+  R   E+        + EE+T E+ E++ ++ + M +  ++    E    ++E 
Sbjct: 265 REQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEE 324

Query: 135 KGSSNIQETDEEDEE--EEDDDDDDEGEDDGEESEETNREEEG---------KAKEQIRN 183
           +     ++  E+ E+  E+ +    + E  GE+ E+  ++EE          K +EQ+R 
Sbjct: 325 QMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRK 384

Query: 184 CENNCQQVTDKAFKEQRDRPEAQEQSEKKISKLDPKK 220
            E   ++  ++  +++    E +EQ  ++  ++  +K
Sbjct: 385 QEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQK 421



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 41/211 (19%), Positives = 93/211 (44%), Gaps = 27/211 (12%)

Query: 9   DQEELLDEEINEDEILANLSAEELKELQSEMEVMAPDPSLPVGMIQKDQTDKPPTGNFNH 68
           +Q +  +E++ + E       E+++E + +M            + QK+QT++        
Sbjct: 241 EQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQM-----LKQKEQTEQEEQTGEQE 295

Query: 69  KSLVDYMYWEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKL--NNE 126
           + + +    E+  R   E+ R      + EE+ +E+ E++ K+ + M +  KE++    E
Sbjct: 296 EQMREQ---EEQMREQEEQMR------EQEEQMREQEEQMGKQEEQMWEQ-KEQMWEQKE 345

Query: 127 IVANKRESKGSSNIQETDEEDEEEEDDDDDDEGEDDGEESEETNREEE----------GK 176
            +  + E  G    Q   +E++  + ++   + E+   + EE  R++E          G+
Sbjct: 346 QMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGE 405

Query: 177 AKEQIRNCENNCQQVTDKAFKEQRDRPEAQE 207
            KEQ+R  E    +  ++  K++    E +E
Sbjct: 406 QKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 29/129 (22%), Positives = 62/129 (48%), Gaps = 6/129 (4%)

Query: 98  EEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRESKGSSNIQETDEEDEEEEDDDDDD 157
           E++ Q   +E + R +      +E    E     RE +G    QE    ++EE+  + ++
Sbjct: 154 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEE 213

Query: 158 E----GEDDGEESEETNREEE--GKAKEQIRNCENNCQQVTDKAFKEQRDRPEAQEQSEK 211
           +     E  GE+ E+  ++EE  G+ +EQ++  E   Q+  ++  K++    E +EQ  +
Sbjct: 214 QMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMRE 273

Query: 212 KISKLDPKK 220
           +  ++  +K
Sbjct: 274 QEEQMLKQK 282



 Score = 36.6 bits (83), Expect = 0.063
 Identities = 30/133 (22%), Positives = 59/133 (44%), Gaps = 8/133 (6%)

Query: 79  KASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRESKGSS 138
           K  +R LE +++P+     E + +E+  ++ ++   + +  +E    E     RE +G  
Sbjct: 35  KELKRKLETDKIPLP---QEGQVREQEGQVREQEGQVRE--QEGQVREQEGQVREQEGQV 89

Query: 139 NIQE---TDEEDEEEEDDDDDDEGEDDGEESEETNREEEGKAKEQIRNCENNCQQVTDKA 195
             QE    ++E +  E +    E E    E E   RE+EG+ +EQ         QV ++ 
Sbjct: 90  REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 149

Query: 196 FKEQRDRPEAQEQ 208
            + +    + +EQ
Sbjct: 150 GQVREQEGQVREQ 162



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 27/112 (24%), Positives = 52/112 (46%), Gaps = 6/112 (5%)

Query: 102 QEEHEEIEKRNKNMAQYLKEKLNNEIVANKRESKGSSNIQETDEEDEEEEDDDDDDEG-- 159
           QEE + +E     +  ++KE L  ++  +K        ++E + +  E+E    + EG  
Sbjct: 17  QEELQLVETEKSEIQLHIKE-LKRKLETDKIPLPQEGQVREQEGQVREQEGQVREQEGQV 75

Query: 160 -EDDGE--ESEETNREEEGKAKEQIRNCENNCQQVTDKAFKEQRDRPEAQEQ 208
            E +G+  E E   RE+EG+ +EQ         QV ++  + +    + +EQ
Sbjct: 76  REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 127



 Score = 34.3 bits (77), Expect = 0.31
 Identities = 44/196 (22%), Positives = 82/196 (41%), Gaps = 17/196 (8%)

Query: 24  LANLSAEELKE----LQSEMEVMAPDPS---LPVGMIQKD-QTDKPPTGNFNHKSLVDYM 75
           +  ++ EELKE    LQ E++++  + S   L +  +++  +TDK P          +  
Sbjct: 1   MPRITNEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQ 60

Query: 76  YWEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRESK 135
             E+  +   +E +V       E++ Q   +E + R +      +E    E     RE +
Sbjct: 61  VREQEGQVREQEGQV------REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 114

Query: 136 GSSNIQE---TDEEDEEEEDDDDDDEGEDDGEESEETNREEEGKAKEQIRNCENNCQQVT 192
           G    QE    ++E +  E +    E E    E E   RE+EG+ +EQ         QV 
Sbjct: 115 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 174

Query: 193 DKAFKEQRDRPEAQEQ 208
           ++  + +    + +EQ
Sbjct: 175 EQEGQVREQEGQVREQ 190



 Score = 34.3 bits (77), Expect = 0.31
 Identities = 34/169 (20%), Positives = 70/169 (41%), Gaps = 9/169 (5%)

Query: 98  EEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRESKGSSNIQE---TDEEDEEEEDDD 154
           E++ Q   +E + R +      +E    E     RE +G    QE    ++E +  E + 
Sbjct: 91  EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 150

Query: 155 DDDEGEDDGEESEETNREEEGKAKE---QIRNCENNCQQVTDKAFKEQRDRPEAQEQ--- 208
              E E    E E   RE+EG+ +E   Q+R  E   ++   +  +++    E +EQ   
Sbjct: 151 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGE 210

Query: 209 SEKKISKLDPKKLALDTSFLKVSTRPSGNQTDLDGSLRRVRKNDPDMKE 257
            E+++ K + +    +    K   +    +  +     +V+K +  M++
Sbjct: 211 QEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRK 259


>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
           sapiens]
          Length = 570

 Score = 52.8 bits (125), Expect = 8e-07
 Identities = 38/152 (25%), Positives = 71/152 (46%), Gaps = 15/152 (9%)

Query: 75  MYWEKASR-RMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLK------------E 121
           M WEK  + R LEE+      ++ +E+ ++E E+I ++ K   Q  K            E
Sbjct: 338 MMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEE 397

Query: 122 KLNN--EIVANKRESKGSSNIQETDEEDEEEEDDDDDDEGEDDGEESEETNREEEGKAKE 179
           K+    E++  + E  G    +  ++E+E +E ++     E+   E E+  RE+E K +E
Sbjct: 398 KIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIRE 457

Query: 180 QIRNCENNCQQVTDKAFKEQRDRPEAQEQSEK 211
           Q    +   +++ ++  K      + QEQ EK
Sbjct: 458 QEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEK 489



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 40/194 (20%), Positives = 92/194 (47%), Gaps = 15/194 (7%)

Query: 75  MYWEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRES 134
           M WEK  +   +EE +     K  E  ++ HE+ + R +   +  +EK+  +    ++E+
Sbjct: 324 MMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEA 383

Query: 135 K---GSSNIQETDEEDEEEED---DDDDDEGEDDGE--ESEETNREEEGKAK---EQIRN 183
           K       I+E +E+  E+E+   + ++  GE + +  E EE  +E+E K +   E+IR 
Sbjct: 384 KMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIRE 443

Query: 184 CENNCQQVTDKAFKEQRDRPEAQEQSEKKISKLDPKKLALDTSFLKVSTRPSGNQTDLDG 243
            E   ++  +K     R++ E  ++ E+K+ + + K    +    +   +    +  +  
Sbjct: 444 QEKKIREQEEKI----REQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIRE 499

Query: 244 SLRRVRKNDPDMKE 257
             +++R+ +  ++E
Sbjct: 500 QEKKIREQEEKIRE 513



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 41/209 (19%), Positives = 87/209 (41%), Gaps = 24/209 (11%)

Query: 3   EHSRNSDQEELLDEEINEDEILANLSAEELKELQSEMEVMAPDPSLPVGMIQKDQTDKPP 62
           E      +EE + E+    E  A +  +E K  + E ++   +  +        Q  +  
Sbjct: 361 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMM--------QEQEEK 412

Query: 63  TGNFNHKSLVDYMYWEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEK 122
            G    K       WE+      +EE++     + EEK +E+ ++I ++ + + +     
Sbjct: 413 MGEQEEKM------WEQEEEMQEQEEKMR----RQEEKIREQEKKIREQEEKIRE----- 457

Query: 123 LNNEIVANKRESKGSSNIQETDEEDEEEEDDDDDDEGEDDGEESEETNREEEGKAKEQIR 182
              E++  + E  G    +  ++E + +E ++     E+   E E+  RE+E K +EQ  
Sbjct: 458 -QEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE 516

Query: 183 NCENNCQQVTDKAFKEQRDRPEAQEQSEK 211
             +   +++ ++  K      + QEQ EK
Sbjct: 517 MMQEQEEKMWEQEEKMCEQEEKMQEQEEK 545



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 45/218 (20%), Positives = 93/218 (42%), Gaps = 22/218 (10%)

Query: 10  QEELLDEEINEDEILANLSAEEL----KELQSEMEVMAPDPSLPVGMIQKDQTDKPPTGN 65
           + E  + ++N  E+   L   +L    ++LQ+E + +  +       +Q    +      
Sbjct: 222 ESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNR 281

Query: 66  FNHKSLVDYMYWEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNN 125
            N +   +   W +  +    EE++     + EEK +E+ E++ ++ + M +  ++    
Sbjct: 282 LNQQQ--EEKMWRQEEKIQEREEKIQ----EQEEKIREQEEKMRRQEEMMWEKEEKMRRQ 335

Query: 126 EIVANKRESK---------GSSNIQETDEEDEEEE---DDDDDDEGEDDGEESEETNREE 173
           E +  ++E K             I+E +E+ +EEE   + +   E E      EE  RE+
Sbjct: 336 EEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ 395

Query: 174 EGKAKEQIRNCENNCQQVTDKAFKEQRDRPEAQEQSEK 211
           E K +EQ    +   +++ ++  K      E QEQ EK
Sbjct: 396 EEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEK 433



 Score = 33.5 bits (75), Expect = 0.53
 Identities = 28/152 (18%), Positives = 73/152 (48%), Gaps = 15/152 (9%)

Query: 79  KASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRESKGSS 138
           K  +R LE  ++    +  +++ Q E + + K  ++++  L+ ++    + N+   +   
Sbjct: 233 KELKRKLERAKL----LLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEE 288

Query: 139 NIQETDEEDEEEEDDDDDDEGEDDGEESEETNREEE---------GKAKEQIRNCENNCQ 189
            +   +E+ +E E+   + E E   E+ E+  R+EE          + +E +   E   +
Sbjct: 289 KMWRQEEKIQEREEKIQEQE-EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIR 347

Query: 190 QVTDKAFKEQRDR-PEAQEQSEKKISKLDPKK 220
           ++ +K  ++++ R  E + Q E+KI + + ++
Sbjct: 348 ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQ 379


>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 828

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 51/209 (24%), Positives = 93/209 (44%), Gaps = 22/209 (10%)

Query: 9   DQEELL---DEEINEDEILANLSAEELKELQSEMEVMAPDPSLPVGMIQKDQTDKPPTGN 65
           DQEE +   DE + E E        E K++  + E M  +        +K Q  +  T +
Sbjct: 504 DQEERMWEQDERLREKEE----RMREQKKMWQQEEKMREE--------KKTQEQEKKTWD 551

Query: 66  FNHKSLVDYMYWEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNN 125
              K   +    E+  +   EEE +     + EEK QE+ E++ ++ + M +  ++    
Sbjct: 552 QEEKMREEERMREREKKMREEEEMMR----EQEEKMQEQEEKMREQEEKMWEQEEKMQEQ 607

Query: 126 EIVANKRESKGSSNIQETDEEDEEE---EDDDDDDEGEDDGEESEETNREEEGKAKEQIR 182
           E    ++E K     +E   +++EE   E ++   E E+   E EE  RE+E K +EQ  
Sbjct: 608 EEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEE 667

Query: 183 NCENNCQQVTDKAFKEQRDRPEAQEQSEK 211
             +   +++ ++  K Q    + +EQ EK
Sbjct: 668 KMQGQEEKMREQEEKMQGQEEKMREQEEK 696



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 45/187 (24%), Positives = 84/187 (44%), Gaps = 19/187 (10%)

Query: 77  WEKASRRMLEEERV--PVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRES 134
           WE+  R   +EER+       + EEK +EE +  E+  K   Q  +EK+  E    +RE 
Sbjct: 510 WEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQ--EEKMREEERMREREK 567

Query: 135 KGSSNIQETDEEDEEEEDDDDDDEGEDDGEESEETNREEEGKAKEQIRNCENNCQQVTDK 194
           K        +EE+   E ++   E E+   E EE   E+E K +EQ    E    +  +K
Sbjct: 568 K------MREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQ----EEKMWEQEEK 617

Query: 195 AF-KEQRDRPEAQE----QSEKKISKLDPKKLALDTSFLKVSTRPSGNQTDLDGSLRRVR 249
            + +E+ D+ + QE    + E+K+ + + K    +    +   +    +  + G   ++R
Sbjct: 618 MWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMR 677

Query: 250 KNDPDMK 256
           + +  M+
Sbjct: 678 EQEEKMQ 684



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 49/248 (19%), Positives = 109/248 (43%), Gaps = 29/248 (11%)

Query: 3   EHSRNSDQEELLDEE---------INEDEILANLSAEELKELQSEMEVMAPDPSLPVGMI 53
           +  +  DQEE + EE         + E+E +     E+++E + +M              
Sbjct: 545 QEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEK-------- 596

Query: 54  QKDQTDKPPTGNFNHKSLVDYMYWEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNK 113
             +Q +K            + M+ ++   +M E+E +     + EEK QE+ E++ ++ +
Sbjct: 597 MWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEM---MWEQEEKMQEQEEKMWEQEE 653

Query: 114 NMAQYLKEKLNNEIVANKRESKGSSNIQETDEEDEEEEDDDDDDEGEDD---GEESEETN 170
            M +  ++    E     +E K     ++   ++E+  + ++   G+++   G+E +   
Sbjct: 654 KMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWG 713

Query: 171 REEEGKAKEQIRNCENNCQQVTDKAFKEQRDRPEAQEQSEKKISKLDPKKLALDTSFLKV 230
           +EE+   +E++R  E   +++ D+  K Q   PE +E+  +    L P K+  + S    
Sbjct: 714 QEEKMWGQEEMREKE---ERIRDQKEKMQERLPEHEERCSEPC--LPPSKVLCNMSHTG- 767

Query: 231 STRPSGNQ 238
           S  P+G +
Sbjct: 768 SVEPAGGE 775



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 29/134 (21%), Positives = 69/134 (51%), Gaps = 3/134 (2%)

Query: 78  EKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRESKGS 137
           EK  R   +E R      + EE+ QE+ E++ ++ + M +  ++    E    ++E +  
Sbjct: 289 EKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMR 348

Query: 138 SNIQETDEEDEE--EEDDDDDDEGEDDGEESEETNREEEGKAKEQIRNCENNCQQVTDKA 195
              Q+  +++E   E+D+   ++ E   E+ +   +EE+ + +E+IR  E   ++  ++ 
Sbjct: 349 EQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMRE-EEET 407

Query: 196 FKEQRDRPEAQEQS 209
            +EQ ++ + QE++
Sbjct: 408 MREQEEKMQKQEEN 421



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 36/137 (26%), Positives = 63/137 (45%), Gaps = 10/137 (7%)

Query: 77  WEKASRRMLEEERV--PVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRES 134
           WE+  R   +EER+       + EEK QEE E I +R K M +  +     E    K+E 
Sbjct: 362 WEQDERLREKEERMREQEKMWEQEEKMQEE-ERIREREKKMREEEETMREQEEKMQKQEE 420

Query: 135 KGSSNIQETDEEDEEEEDDDDDDEG---EDDGEESEETNREEEGKAKEQIRNCENNCQQV 191
               N+ E +E++ +++   +  E    ++  +E EE   E+E K ++Q        +  
Sbjct: 421 ----NMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMW 476

Query: 192 TDKAFKEQRDRPEAQEQ 208
             +  +EQ D+   QE+
Sbjct: 477 RQEKMREQEDQMWEQEE 493



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 45/209 (21%), Positives = 94/209 (44%), Gaps = 21/209 (10%)

Query: 10  QEELLDEEINEDEILANLSAEELKELQSEMEVMAPDPSLPVGMIQKDQTDKPPTGNFNHK 69
           QE+L   E  + EI   L+ +ELK      + + P   +    +Q++   +        K
Sbjct: 193 QEKLRLAESEKSEI--QLNVKELKRKLERAKFLLPQ--VQTNTLQEEMWRQEEELREQEK 248

Query: 70  SLVDYMYWEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKE--KLNNEI 127
            +      ++  +   +EER+     + E K +E+ E++ ++ K + +  KE  +   E+
Sbjct: 249 KIR-----KQEEKMWRQEERLR----EQEGKMREQEEKMRRQEKRLREQEKELREQEKEL 299

Query: 128 VANKRESKGSSNIQETDEEDEEEEDDDDDDE-----GEDDGEESEETNREEEGKAKEQIR 182
              K+  +    +QE +E+  E+E+   + E      E+   E E+  RE+E K ++Q  
Sbjct: 300 REQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEE 359

Query: 183 NCENNCQQVTDKAFKEQRDRPEAQEQSEK 211
                 +++ +K  +  R++ +  EQ EK
Sbjct: 360 RMWEQDERLREKE-ERMREQEKMWEQEEK 387



 Score = 38.5 bits (88), Expect = 0.016
 Identities = 29/137 (21%), Positives = 66/137 (48%), Gaps = 3/137 (2%)

Query: 78  EKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRESKGS 137
           EK  R   +E R     ++ ++K +E+ E+++++ + M +  +EK+  +     R+ +  
Sbjct: 282 EKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQ-EEKMREQEEKMWRQEERL 340

Query: 138 SNIQETDEEDEEEEDDDDDDEGEDDGE--ESEETNREEEGKAKEQIRNCENNCQQVTDKA 195
              ++   E E++  D ++   E D    E EE  RE+E   +++ +  E    +  +K 
Sbjct: 341 WEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKK 400

Query: 196 FKEQRDRPEAQEQSEKK 212
            +E+ +    QE+  +K
Sbjct: 401 MREEEETMREQEEKMQK 417



 Score = 37.7 bits (86), Expect = 0.028
 Identities = 23/140 (16%), Positives = 66/140 (47%), Gaps = 4/140 (2%)

Query: 77  WEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRESKG 136
           WE+  +   +EE++     + EE+  E+ +++ ++ + M    +     +    ++E + 
Sbjct: 320 WEQEEKMREQEEKM----WRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERM 375

Query: 137 SSNIQETDEEDEEEEDDDDDDEGEDDGEESEETNREEEGKAKEQIRNCENNCQQVTDKAF 196
               +  ++E++ +E++   +  +   EE E    +EE   K++    E   ++   +  
Sbjct: 376 REQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRL 435

Query: 197 KEQRDRPEAQEQSEKKISKL 216
            EQ+++   QE+ +++  K+
Sbjct: 436 PEQKEKLWEQEKMQEQEEKI 455



 Score = 37.4 bits (85), Expect = 0.037
 Identities = 45/221 (20%), Positives = 93/221 (42%), Gaps = 38/221 (17%)

Query: 1   MSEHSRNSDQEELLDEEINEDEILANLSAEELKELQSEMEVMAPDPSLPVGMIQKDQTDK 60
           M E  +  +QEE + EE            E  K+++ E E M            ++Q +K
Sbjct: 375 MREQEKMWEQEEKMQEE--------ERIREREKKMREEEETM------------REQEEK 414

Query: 61  PPTGNFNHKSLVDYMYWEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLK 120
                 N         WE+  +   +++R+P    + +EK  E+ +  E+  K   Q  K
Sbjct: 415 MQKQEEN--------MWEQEEKEW-QQQRLP----EQKEKLWEQEKMQEQEEKIWEQEEK 461

Query: 121 EKLNNEIVANKRESKGSSNIQETDEEDEEEEDDDDDDE-----GEDDGEESEETNREEEG 175
            +   E+   +++      ++E +++  E+E+   D E      E+   E +E  RE+E 
Sbjct: 462 IRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEE 521

Query: 176 KAKEQIRNCENNCQQVTDKAFKEQRDRPEAQEQSEKKISKL 216
           + +EQ +  +   +   +K  +EQ  +   QE+  ++  ++
Sbjct: 522 RMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERM 562



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 26/131 (19%), Positives = 65/131 (49%), Gaps = 8/131 (6%)

Query: 96  KSEEKTQEEHEEIEKRNKNM---AQYLKEKLNNEIVANKRESKGSSNIQETDEEDEEEED 152
           + EE+ +E+ ++I K+ + M    + L+E+        ++  +    ++E ++E  E+E 
Sbjct: 238 RQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEK 297

Query: 153 DDDDD----EGEDDGEESEETNREEEGKAKEQIRNCENNCQQVTDKAFKEQRDRPEAQEQ 208
           +  +     E E+  +E EE   E+E K +EQ        +++ ++  K+ R++ +    
Sbjct: 298 ELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQE-KQMREQEQKMRD 356

Query: 209 SEKKISKLDPK 219
            E+++ + D +
Sbjct: 357 QEERMWEQDER 367



 Score = 35.0 bits (79), Expect = 0.18
 Identities = 33/145 (22%), Positives = 66/145 (45%), Gaps = 18/145 (12%)

Query: 77  WEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLK-----EKLNNEIVANK 131
           WE+  +   +E+++       EE+  E+ E + ++ + M +  K     EK+  E    +
Sbjct: 341 WEQEKQMREQEQKMR----DQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIRE 396

Query: 132 RESKGSSNIQETDEEDEEEEDDDDDDEGEDDGEESEETNREEEGKAKEQIRNCENNCQQV 191
           RE K    ++E +E   E+E+     E     +E +E  ++   + KE++   E    Q 
Sbjct: 397 REKK----MREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKL--WEQEKMQE 450

Query: 192 TDKAFKEQRDRPEAQEQ---SEKKI 213
            ++   EQ ++   QE+    EKK+
Sbjct: 451 QEEKIWEQEEKIRDQEEMWGQEKKM 475



 Score = 35.0 bits (79), Expect = 0.18
 Identities = 32/147 (21%), Positives = 65/147 (44%), Gaps = 29/147 (19%)

Query: 77  WEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRESKG 136
           WE+  +   +E+++       EE+  E+ E + ++ + M +  K     E     RE K 
Sbjct: 489 WEQEEKMRDQEQKM----WDQEERMWEQDERLREKEERMREQKKMWQQEE---KMREEK- 540

Query: 137 SSNIQETDEEDEEEEDDDDDDEGEDDGEESEETNREEEGKAKEQIRNCENNCQQVTDKAF 196
                +T E++++  D ++    E+   E E+  REEE   +EQ            ++  
Sbjct: 541 -----KTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQ------------EEKM 583

Query: 197 KEQRDRPEAQE----QSEKKISKLDPK 219
           +EQ ++   QE    + E+K+ + + K
Sbjct: 584 QEQEEKMREQEEKMWEQEEKMQEQEEK 610



 Score = 34.3 bits (77), Expect = 0.31
 Identities = 44/218 (20%), Positives = 87/218 (39%), Gaps = 14/218 (6%)

Query: 3   EHSRNSDQEELLDEEINEDEILANLSAEELKELQSEMEVMAPDPSLPVGMIQKDQTDKPP 62
           E     ++E + ++E    +   N+  +E KE Q +     P+    +   +K Q  +  
Sbjct: 398 EKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQR---LPEQKEKLWEQEKMQEQEEK 454

Query: 63  TGNFNHKSLVDYMYW--EKASRRMLEEERVPVTFVKSEEKTQEEHEEI---EKRNKNMAQ 117
                 K       W  EK   R  +         + EEK +++ +++   E+R     +
Sbjct: 455 IWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDE 514

Query: 118 YLKEKLNNEIVANKRESKGSSNIQETDEEDEEEEDDDDDDE----GEDDGEESEETNREE 173
            L+EK   E +  +++          +++ +E+E    D E     E+   E E+  REE
Sbjct: 515 RLREK--EERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREE 572

Query: 174 EGKAKEQIRNCENNCQQVTDKAFKEQRDRPEAQEQSEK 211
           E   +EQ    +   +++ ++  K      + QEQ EK
Sbjct: 573 EEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEK 610



 Score = 33.5 bits (75), Expect = 0.53
 Identities = 25/132 (18%), Positives = 65/132 (49%), Gaps = 5/132 (3%)

Query: 77  WEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRESKG 136
           W +  R   +E+++     + E+K +++ E + ++++ + +  +E++  +    ++E K 
Sbjct: 334 WRQEERLWEQEKQMR----EQEQKMRDQEERMWEQDERLREK-EERMREQEKMWEQEEKM 388

Query: 137 SSNIQETDEEDEEEEDDDDDDEGEDDGEESEETNREEEGKAKEQIRNCENNCQQVTDKAF 196
               +  + E +  E+++   E E+  ++ EE   E+E K  +Q R  E   +    +  
Sbjct: 389 QEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKM 448

Query: 197 KEQRDRPEAQEQ 208
           +EQ ++   QE+
Sbjct: 449 QEQEEKIWEQEE 460



 Score = 33.1 bits (74), Expect = 0.69
 Identities = 32/147 (21%), Positives = 66/147 (44%), Gaps = 34/147 (23%)

Query: 95  VKSEEKTQEEHE------------------EIEKRNKNMAQYLKEKLNNEIVANKRESKG 136
           ++ +E+   E E                  E EK+ +   Q ++++       ++R  + 
Sbjct: 312 MQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREK 371

Query: 137 SSNIQETD---EEDEEEEDDDDDDEGEDDGEESEETNREEEGKAKEQIRNCENNCQQVTD 193
              ++E +   E++E+ ++++   E E    E EET RE+E K ++Q    E N  +  +
Sbjct: 372 EERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQ----EENMWEQEE 427

Query: 194 KAFKEQR---------DRPEAQEQSEK 211
           K +++QR         ++ + QEQ EK
Sbjct: 428 KEWQQQRLPEQKEKLWEQEKMQEQEEK 454


>gi|55956788 nucleolin [Homo sapiens]
          Length = 710

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 29/123 (23%), Positives = 57/123 (46%), Gaps = 12/123 (9%)

Query: 96  KSEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRESKGSSNIQETDEEDEEEEDDDD 155
           + +E   ++ E+  +         K K   ++V  K ++      +E D+EDE+++DD+D
Sbjct: 193 EDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDED 252

Query: 156 DDEGEDDGEESEETNREEEGKAKEQIRNCENNCQQVTDKAFKEQRDRPEAQEQSEKKISK 215
           D++ +D+ +E EE   EEE              ++   K  KE   +  A E  ++K+  
Sbjct: 253 DEDDDDEDDEEEEEEEEEE------------PVKEAPGKRKKEMAKQKAAPEAKKQKVEG 300

Query: 216 LDP 218
            +P
Sbjct: 301 TEP 303



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 32/115 (27%), Positives = 58/115 (50%), Gaps = 4/115 (3%)

Query: 96  KSEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRESKGSSNIQETDEEDEEEEDDDD 155
           K E+  +EE ++ E+  ++     +++   E  A K  +   ++  E DE+DE++EDDDD
Sbjct: 141 KKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDD 200

Query: 156 DDEGEDDGEESEETNREEEGKAKEQIRNCENNCQQVTDKAFKEQRDRPEAQEQSE 210
           D+E +D  EE+ ET      K K+  +      + V +   +E+ D  E  +  E
Sbjct: 201 DEE-DDSEEEAMETT---PAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDE 251



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 23/87 (26%), Positives = 45/87 (51%)

Query: 134 SKGSSNIQETDEEDEEEEDDDDDDEGEDDGEESEETNREEEGKAKEQIRNCENNCQQVTD 193
           +KG+ N +   +ED +EE+DDD +E E+D E+ +E   E E  A +       +  +  +
Sbjct: 131 AKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDE 190

Query: 194 KAFKEQRDRPEAQEQSEKKISKLDPKK 220
               ++ D  + ++ SE++  +  P K
Sbjct: 191 DDEDDEDDDDDEEDDSEEEAMETTPAK 217



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 26/98 (26%), Positives = 48/98 (48%), Gaps = 4/98 (4%)

Query: 131 KRESKGSSNIQETDEEDEEEEDDDDDDEGEDDGE----ESEETNREEEGKAKEQIRNCEN 186
           K   K  S+ +E D+ +E+EEDD+D+DE ED+ E    ++       E +  E   + E+
Sbjct: 138 KNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDED 197

Query: 187 NCQQVTDKAFKEQRDRPEAQEQSEKKISKLDPKKLALD 224
           +     D + +E  +   A+ +   K+  +  K +A D
Sbjct: 198 DDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAED 235



 Score = 37.7 bits (86), Expect = 0.028
 Identities = 25/94 (26%), Positives = 45/94 (47%), Gaps = 4/94 (4%)

Query: 130 NKRESKGSSNIQETDEEDEEEEDDDDDDEGEDDGEESEETNREEEGKAKEQIRNCENNCQ 189
           N + +K   + +E D++ EE+E+DD+D++ ++D  E           A E   + E++  
Sbjct: 136 NGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASED-EDDEDDED 194

Query: 190 QVTDKAFKEQRDRPEAQEQSE---KKISKLDPKK 220
              D   +E     EA E +    KK +K+ P K
Sbjct: 195 DEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVK 228


>gi|190014588 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo
           sapiens]
          Length = 530

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 55/279 (19%), Positives = 115/279 (41%), Gaps = 38/279 (13%)

Query: 73  DYMYWEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKR 132
           D +  E  S++  +EE+ P    K +E+ Q+E ++  K          +K   + V +KR
Sbjct: 209 DIITEEDKSKKKGQEEKQPKKQPKKDEEGQKEEDKPRKEPD-------KKEGKKEVESKR 261

Query: 133 ESKGSSNIQETDEEDEEEEDDDDDDEGEDDGEESEETNREEEGKAKEQIRNCENNCQQVT 192
           ++   + +  T   D EEE DD + E +  G  + +T         +  +   +  ++  
Sbjct: 262 KNLAKTGVTSTS--DSEEEGDDQEGEKKRKGGRNFQTAHRRNMLKGQHEKEAADRKRKQE 319

Query: 193 DKAFKEQRDRPEAQEQSEKKISKLDPKKLALDTSFLKVSTRPSGNQTDLDGSLRRVR--- 249
           ++   EQ+++ E ++   KK+ K                      +T +D  L+R+    
Sbjct: 320 EQMETEQQNKDEGKKPEVKKVEK--------------------KRETSMDSRLQRIHAEI 359

Query: 250 KNDPDMKELNLNNIENIPKEMLLDFVNAMKKNKHIKTFSLANVGADENVAFALANMLREN 309
           KN   +  L++N       E+    V   +  KH +  +       +   F ++ ++ E 
Sbjct: 360 KNSLKIDNLDVNRCIEALDELASLQVTMQQAQKHTEMITTLK----KIRRFKVSQVIMEK 415

Query: 310 RSITTLNIESNFITGKGIVAIMRCLQFNETLTELRFHNQ 348
            ++     ++ F+ G+G   I + L  N++L E R H +
Sbjct: 416 STMLYNKFKNMFLVGEGDSVITQVL--NKSLAEQRQHEE 452


>gi|19923653 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo
           sapiens]
          Length = 530

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 55/279 (19%), Positives = 115/279 (41%), Gaps = 38/279 (13%)

Query: 73  DYMYWEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKR 132
           D +  E  S++  +EE+ P    K +E+ Q+E ++  K          +K   + V +KR
Sbjct: 209 DIITEEDKSKKKGQEEKQPKKQPKKDEEGQKEEDKPRKEPD-------KKEGKKEVESKR 261

Query: 133 ESKGSSNIQETDEEDEEEEDDDDDDEGEDDGEESEETNREEEGKAKEQIRNCENNCQQVT 192
           ++   + +  T   D EEE DD + E +  G  + +T         +  +   +  ++  
Sbjct: 262 KNLAKTGVTSTS--DSEEEGDDQEGEKKRKGGRNFQTAHRRNMLKGQHEKEAADRKRKQE 319

Query: 193 DKAFKEQRDRPEAQEQSEKKISKLDPKKLALDTSFLKVSTRPSGNQTDLDGSLRRVR--- 249
           ++   EQ+++ E ++   KK+ K                      +T +D  L+R+    
Sbjct: 320 EQMETEQQNKDEGKKPEVKKVEK--------------------KRETSMDSRLQRIHAEI 359

Query: 250 KNDPDMKELNLNNIENIPKEMLLDFVNAMKKNKHIKTFSLANVGADENVAFALANMLREN 309
           KN   +  L++N       E+    V   +  KH +  +       +   F ++ ++ E 
Sbjct: 360 KNSLKIDNLDVNRCIEALDELASLQVTMQQAQKHTEMITTLK----KIRRFKVSQVIMEK 415

Query: 310 RSITTLNIESNFITGKGIVAIMRCLQFNETLTELRFHNQ 348
            ++     ++ F+ G+G   I + L  N++L E R H +
Sbjct: 416 STMLYNKFKNMFLVGEGDSVITQVL--NKSLAEQRQHEE 452


>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
            [Homo sapiens]
          Length = 2073

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 31/127 (24%), Positives = 66/127 (51%), Gaps = 10/127 (7%)

Query: 78   EKASRRMLEE----ERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRE 133
            EK + R++E+    E+     + +   +++   +++ +NK    YL    +  +   + +
Sbjct: 1005 EKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNK----YLHSPESRPVTGERGQ 1060

Query: 134  SKGSSNIQETDEEDEEEEDDDDDDEGEDDGEESEETNREEEGKAKEQIRNCENNCQQVTD 193
                S  +E+ EE+EEEED+++++E E++ E+ EE   EEE + +E I++      +   
Sbjct: 1061 LLELS--KESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQS 1118

Query: 194  KAFKEQR 200
             A K +R
Sbjct: 1119 VAIKRKR 1125



 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 46/199 (23%), Positives = 78/199 (39%), Gaps = 28/199 (14%)

Query: 95   VKSEEKTQEEHEEIEKRNKNMAQ---------------YLKEKLNNEIVANKRESKGSSN 139
            +K EE+ +EE EE E+  +   +                 +EK   EI   K +S    +
Sbjct: 1348 IKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDD 1407

Query: 140  IQETDEEDEEEEDDDDDDEGEDDGEESEETNREEEGKAKEQIRNCENNCQQVTDKAFKEQ 199
             +E +EEDEE   ++D D  ++D    E    E+E   +E  +    N +   D   +  
Sbjct: 1408 HEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVLENQETFLDLNVQPG 1467

Query: 200  RDRPEAQEQSEKKIS---KLDPKKLALDTSFLKVSTR--PSGNQTDLDGSLRRVRKNDPD 254
               PE        ++     +PK+LA D   +  S    P G Q          +++  +
Sbjct: 1468 HSNPEVLMDCGVDLTASCNSEPKELAGDPEAVPESDEEPPPGEQAQ--------KQDQKN 1519

Query: 255  MKELNLNNIENIPKEMLLD 273
             KE++    E  P  M +D
Sbjct: 1520 SKEVDTEFKEGNPATMEID 1538



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 37/129 (28%), Positives = 58/129 (44%), Gaps = 11/129 (8%)

Query: 84   MLEEERVPVTFVK--SEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRESKGSSNIQ 141
            M  +E+V V   K  SE KT      IE+  K   + L  +  N     +RE   +    
Sbjct: 1281 MEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQEEN-----RREETCAPVSP 1335

Query: 142  ETDEEDEEEEDDDDDDEGEDDGEESEETNREEEGKAKEQIRNCENNCQQVTDKAFKEQRD 201
             T   ++ E+D    +E E++ EE EE   EEEG+ +E   N E +     D A  ++++
Sbjct: 1336 NTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKD----PDGAKSQEKE 1391

Query: 202  RPEAQEQSE 210
             PE   + E
Sbjct: 1392 EPEISTEKE 1400


>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 899

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 35/144 (24%), Positives = 74/144 (51%), Gaps = 19/144 (13%)

Query: 77  WEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRESKG 136
           WE+  +   +E+++       EE+  E+ E + ++ + M +  +EK+  ++   + E K 
Sbjct: 379 WEQEKQMREQEQKMR----DQEERMWEQDERLREKEERMRE--QEKMWEQVEKMREEKKM 432

Query: 137 SSNIQETDEEDEEEEDDDDDDEGEDDGEESEETNREEEGKAKEQIRNCENNCQQVTDKAF 196
               ++T +++E+ ++++   E E    E EET RE+E K ++Q    E N  +  +K +
Sbjct: 433 QEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQ----EENMWEQEEKEW 488

Query: 197 KEQR---------DRPEAQEQSEK 211
           ++QR         ++ + QEQ EK
Sbjct: 489 QQQRLPEQKEKLWEQEKMQEQEEK 512



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 38/156 (24%), Positives = 72/156 (46%), Gaps = 13/156 (8%)

Query: 77  WEKASRRMLEEERVPVTFVKSEEKTQE------EHEEIEKRNKNMAQYLKEKLNNEIVAN 130
           WE+  +   +E+++     + E+KTQE      + EE  +  + M +  K+    E +  
Sbjct: 547 WEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMR 606

Query: 131 KRESKGSSNIQETDEEDEEE-EDDDDDDEGEDDGEESEETNREEEGKAKEQIRNCE---- 185
           ++E K     ++  E++E+  E ++   E E+   E EE   E+E K  EQ R  E    
Sbjct: 607 EQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEK 666

Query: 186 --NNCQQVTDKAFKEQRDRPEAQEQSEKKISKLDPK 219
              + +    +  +EQ ++   QE+ EKK  + + K
Sbjct: 667 LWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKK 702



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 34/174 (19%), Positives = 83/174 (47%), Gaps = 12/174 (6%)

Query: 86  EEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRESKGSSNIQETDE 145
           +EER+     + E K +E+ E++ ++ K + +  KE    E    +++       Q  ++
Sbjct: 298 QEERLR----EQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQ 353

Query: 146 EDEEEEDDDDDDEGEDDGEESEETNREEEGKAKEQIRNCENNCQQV--TDKAFKEQRDRP 203
           E++  E ++   E E+     EE   E+E + +EQ +   +  +++   D+  +E+ +R 
Sbjct: 354 EEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERM 413

Query: 204 EAQEQSEKKISKLDPKKLALDTSFLKVSTRPSGNQTDLDGSLRRVRKNDPDMKE 257
             QE+  +++ K+  +K       ++   + + +Q +      R+R+ +  M+E
Sbjct: 414 REQEKMWEQVEKMREEKK------MQEQEKKTRDQEEKMQEEERIREREKKMRE 461



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 45/217 (20%), Positives = 96/217 (44%), Gaps = 23/217 (10%)

Query: 9   DQEELLDEEINEDEILANLSAEELKE---LQSEMEVMAPDPSLPVGMIQKDQTDKPPTGN 65
           DQEE ++++  E E       E+++E   ++   + M  +  +     +K Q  +     
Sbjct: 562 DQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQE 621

Query: 66  FNHKSLVDYMYWEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLK----E 121
              K       WE+  +   +EE++     + EEK  E+ E++ ++ +   Q  K    E
Sbjct: 622 QEEKM------WEQEEKMQEQEEKM----WEQEEKMWEQEEKMWEQQRLPEQKEKLWEHE 671

Query: 122 KLNNEIVANKRESK--GSSNIQETDEEDEEEEDDDDDDEGEDDGEESEETNREEEGKAKE 179
           K+  +    ++E K      +++  +E E++  D +    E+   E E+  REEE    E
Sbjct: 672 KMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEE----E 727

Query: 180 QIRNCENNCQQVTDKAFKEQRDRPEAQEQSEKKISKL 216
            +R  E   Q+  +K  +++ +  E +E+  ++  K+
Sbjct: 728 MMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKM 764



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 45/222 (20%), Positives = 95/222 (42%), Gaps = 24/222 (10%)

Query: 3   EHSRNSDQEELLDEE--INEDEILANLSAEELKELQSEMEVMAPDPSLPVGMIQKDQTDK 60
           +  +  DQEE + EE  I E E       E ++E + +M+    +      M ++++ + 
Sbjct: 435 QEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEEN------MWEQEEKEW 488

Query: 61  PPTGNFNHKSLVDYMYWEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLK 120
                   K  +    WE+   +  EE+      +  +E+   + EE+  + K M +  K
Sbjct: 489 QQQRLPEQKEKL----WEQEKMQEQEEK------IWEQEEKIRDQEEMWGQEKKMWRQEK 538

Query: 121 EKLNNEIVANKRESKGSSNIQETDEEDEEEEDDDDDDEGEDDGEE---SEETNREEEGKA 177
            +   + +  + E       +  D+E+  E+   + ++   D EE    EE  RE E K 
Sbjct: 539 MREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKM 598

Query: 178 KEQ---IRNCENNCQQVTDKAFKEQRDRPEAQEQSEKKISKL 216
           +E+   +R  E   Q+  +K  +++    E +E+ +++  K+
Sbjct: 599 REEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKM 640



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 40/218 (18%), Positives = 95/218 (43%), Gaps = 21/218 (9%)

Query: 5   SRNSDQEELLDEEINEDEILA------NLSAEELKELQSEMEVMAPDPSLPVGMIQKDQT 58
           +R+   +  ++E   E + L+       ++ EELK+  +E++       LP+   +K + 
Sbjct: 190 TRHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQ-----EKLPLAESEKSEI 244

Query: 59  DKPPTGNFNHKSLVDYMYWEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQY 118
                   N K L   +   K     ++   +     + EE+ +E+ ++I K+ + M + 
Sbjct: 245 Q------LNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQ 298

Query: 119 LKEKLNNEIVANKRESKGSSNIQETDEEDEEEEDDDDDDEGEDDGEESEETNREEEGKAK 178
            +     E    ++E K     +   E+++E  + + +   + +  E EE  +E+E K  
Sbjct: 299 EERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMW 358

Query: 179 EQIRNCENNCQQVTDKAFKEQRDRPEAQEQSEKKISKL 216
           EQ    E   ++  +K ++++    E ++Q  ++  K+
Sbjct: 359 EQ----EEKMREQEEKMWRQEERLWEQEKQMREQEQKM 392



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 33/147 (22%), Positives = 70/147 (47%), Gaps = 12/147 (8%)

Query: 79  KASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRESK--- 135
           +  +R+ E+E+     ++ +EK   E +E+ ++ + M +  ++    E    ++E K   
Sbjct: 318 RQEKRLREQEKE----LREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWR 373

Query: 136 GSSNIQETDEEDEEEEDDDDDDEGEDDGEESEETNREEEGKAKEQIRNCENNCQQVTDKA 195
               + E +++  E+E    D E  +   E +E  RE+E + +EQ +  E   +   +K 
Sbjct: 374 QEERLWEQEKQMREQEQKMRDQE--ERMWEQDERLREKEERMREQEKMWEQVEKMREEKK 431

Query: 196 FKEQRDRPEAQE---QSEKKISKLDPK 219
            +EQ  +   QE   Q E++I + + K
Sbjct: 432 MQEQEKKTRDQEEKMQEEERIREREKK 458



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 42/216 (19%), Positives = 94/216 (43%), Gaps = 7/216 (3%)

Query: 9   DQEELLDEEINEDEILANLSAEELKELQSEMEVMAPDPSLPVGMIQKDQTDKPPTGNFNH 68
           +QEE + E+    E    L   E  + Q +M+           M +K Q  +  T  ++ 
Sbjct: 649 EQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKT--WDQ 706

Query: 69  KSLVDYMYWEKASRRMLEEERV----PVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLN 124
           + + +     +  ++M EEE +         + EEK QE+ EE+ ++ + M +  ++   
Sbjct: 707 EKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWE 766

Query: 125 NEIVANKRESKGSSNIQETDEEDEEEEDDDDDDEGEDDGEESEETNREEEGKAKEQ-IRN 183
            + +  ++E        +  E+  E+E+   D E +  G+E +   +EE+ + +E+ +  
Sbjct: 767 QQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWG 826

Query: 184 CENNCQQVTDKAFKEQRDRPEAQEQSEKKISKLDPK 219
            E       +K + ++      +E+ E+K+   + K
Sbjct: 827 QEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEK 862



 Score = 37.4 bits (85), Expect = 0.037
 Identities = 44/216 (20%), Positives = 95/216 (43%), Gaps = 17/216 (7%)

Query: 7   NSDQEELL--DEEINEDEILANLSAEEL---KELQSEMEVMAPDPSLPVGMIQKDQTDKP 61
           N+ QEE+   +EE+ E E       E++   +E   E E    +    +   +K   ++ 
Sbjct: 268 NTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQE 327

Query: 62  PTGNFNHKSLVDYMYWEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKE 121
                  K L +     +   +M E+E       + EEK +E+ E++ ++ + + +  K+
Sbjct: 328 KELREQEKELREQKELREQEEQMQEQEE---KMWEQEEKMREQEEKMWRQEERLWEQEKQ 384

Query: 122 KLNNEIVANKRESK---GSSNIQETDEEDEEEE---DDDDDDEGEDDGEESEETNREEEG 175
               E     +E +       ++E +E   E+E   +  +    E   +E E+  R++E 
Sbjct: 385 MREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEE 444

Query: 176 KAKEQ--IRNCENNCQQVTDKAFKEQRDRPEAQEQS 209
           K +E+  IR  E   ++  ++  +EQ ++ + QE++
Sbjct: 445 KMQEEERIREREKKMRE-EEETMREQEEKMQKQEEN 479



 Score = 37.0 bits (84), Expect = 0.048
 Identities = 28/139 (20%), Positives = 63/139 (45%), Gaps = 6/139 (4%)

Query: 78  EKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRESKGS 137
           EK  R   +E R      + EE+ QE+ E++ ++ + M +        E +  + E    
Sbjct: 327 EKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMRE------QEEKMWRQEERLWE 380

Query: 138 SNIQETDEEDEEEEDDDDDDEGEDDGEESEETNREEEGKAKEQIRNCENNCQQVTDKAFK 197
              Q  ++E +  + ++   E ++   E EE  RE+E   ++  +  E    Q  +K  +
Sbjct: 381 QEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTR 440

Query: 198 EQRDRPEAQEQSEKKISKL 216
           +Q ++ + +E+  ++  K+
Sbjct: 441 DQEEKMQEEERIREREKKM 459



 Score = 36.6 bits (83), Expect = 0.063
 Identities = 37/209 (17%), Positives = 90/209 (43%), Gaps = 12/209 (5%)

Query: 1   MSEHSRNSDQEELLDEEINEDEILANLSAEELKELQSEMEVMAPDPSLPVGMIQKDQTDK 60
           M + ++  +++    E++ E+E +     E  K+++ E E+M           +K Q  +
Sbjct: 692 MEKKTQEQEKKTWDQEKMREEESMR----EREKKMREEEEMMREQEEKMQEQEEKMQEQE 747

Query: 61  PPTGNFNHKSLVDYMYWEKASRRMLEEERVPVTFVKS-EEKTQEEHEEIEKRNKNMAQYL 119
                   K       WE+   +M E++R+P    K  E +  +E E+I ++ + M    
Sbjct: 748 EEMWEQEEKM------WEQ-EEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQE 800

Query: 120 KEKLNNEIVANKRESKGSSNIQETDEEDEEEEDDDDDDEGEDDGEESEETNREEEGKAKE 179
           ++    E     +E K     ++   ++E+    ++   G+++    +E   EE+ + +E
Sbjct: 801 EKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQE 860

Query: 180 QIRNCENNCQQVTDKAFKEQRDRPEAQEQ 208
           +    +    +  ++  +EQ ++   QE+
Sbjct: 861 EKMREQEEKMRGQEEKMREQEEKMRGQEE 889



 Score = 35.0 bits (79), Expect = 0.18
 Identities = 55/254 (21%), Positives = 99/254 (38%), Gaps = 53/254 (20%)

Query: 3   EHSRNSDQEELL---DEEINEDEILANLSAEELKELQSEMEVMAPDPSLPVGMIQKDQTD 59
           +  +  DQEE +   DE + E E        E +++  ++E M  +        +K Q  
Sbjct: 388 QEQKMRDQEERMWEQDERLREKEE----RMREQEKMWEQVEKMREE--------KKMQEQ 435

Query: 60  KPPTGNFNHKSLVDYMYWEKASRRMLEEERVPVTFVKSEEKTQEEHEEI-EKRNKNMAQY 118
           +  T +   K   +    E+  +   EEE    T  + EEK Q++ E + E+  K   Q 
Sbjct: 436 EKKTRDQEEKMQEEERIREREKKMREEEE----TMREQEEKMQKQEENMWEQEEKEWQQQ 491

Query: 119 L----KEKL---------------NNEIVANKRESKGSSNIQETDEEDEEEEDD------ 153
                KEKL                 E + ++ E  G        E+  E+ED       
Sbjct: 492 RLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEE 551

Query: 154 ---DDDDEGEDDGEESEETNREEEGKAKEQIRNC-ENNCQQVTDKAFKEQ----RDRPEA 205
              D + +  D  E  E+  +E+E K  +Q     E    +  +K  +E+    R++ E 
Sbjct: 552 KMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEK 611

Query: 206 QEQSEKKISKLDPK 219
            ++ E+K+ + + K
Sbjct: 612 MQEQEEKMQEQEEK 625



 Score = 30.8 bits (68), Expect = 3.4
 Identities = 37/184 (20%), Positives = 83/184 (45%), Gaps = 22/184 (11%)

Query: 9   DQEELL---DEEINEDEILANLSAEELKELQSEM----EVMAPDPSLPVGMIQKDQTDKP 61
           ++EE++   +E++ E E       EE+ E + +M    E M     LP    QK++    
Sbjct: 724 EEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPE---QKEKL--- 777

Query: 62  PTGNFNHKSLVDY-MYWEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLK 120
               + H+ + +    WE+  +   +EE++       EEK + + E++  + + M    +
Sbjct: 778 ----WEHEKMQEQEKIWEQEEKMRDQEEKMR----GQEEKMRGQEEKMRGQEEKMWGQEE 829

Query: 121 EKLNNEIVANKRESKGSSNIQETDEEDEEEEDDDDDDEGEDDGEESEETNREEEGKAKEQ 180
           +    E     +E K     ++ +E+ + +E+   + E +  G+E +   +EE+ + +E+
Sbjct: 830 KMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEE 889

Query: 181 IRNC 184
              C
Sbjct: 890 KIYC 893



 Score = 29.3 bits (64), Expect = 10.0
 Identities = 21/109 (19%), Positives = 48/109 (44%), Gaps = 1/109 (0%)

Query: 396 KQRQKRQEEQKQQQLKEQKKLIAMLENGLGLPPGMWELLGGPKPDSRMQEFFQPPPPRPP 455
           ++++++  EQ+++  ++++K+    E        MWE    P+   ++ E  +       
Sbjct: 620 QEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKM 679

Query: 456 NPQNVPFSQRSEMMKKPSQAPKYRTDPDSFRVVKLKRIQRKSRMPEARE 504
             Q     ++ +M KK  +  K   D +  R  +  R +R+ +M E  E
Sbjct: 680 QEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMR-EREKKMREEEE 727


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.129    0.356 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,673,442
Number of Sequences: 37866
Number of extensions: 1400004
Number of successful extensions: 35099
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 816
Number of HSP's successfully gapped in prelim test: 938
Number of HSP's that attempted gapping in prelim test: 12678
Number of HSP's gapped (non-prelim): 10889
length of query: 560
length of database: 18,247,518
effective HSP length: 107
effective length of query: 453
effective length of database: 14,195,856
effective search space: 6430722768
effective search space used: 6430722768
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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