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Search of human proteins with 5454016
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5454016 retinitis pigmentosa RP1 protein [Homo sapiens]
(2156 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5454016 retinitis pigmentosa RP1 protein [Homo sapiens] 4312 0.0
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 172 2e-42
gi|30181244 doublecortin isoform c [Homo sapiens] 96 4e-19
gi|30181242 doublecortin isoform b [Homo sapiens] 96 4e-19
gi|30181240 doublecortin isoform c [Homo sapiens] 96 4e-19
gi|30181246 doublecortin isoform a [Homo sapiens] 96 4e-19
gi|156713428 doublecortin-like kinase 2 isoform a [Homo sapiens] 94 1e-18
gi|156713430 doublecortin-like kinase 2 isoform b [Homo sapiens] 94 2e-18
gi|4758128 doublecortin-like kinase 1 [Homo sapiens] 91 2e-17
gi|117938307 doublecortin domain containing 2 [Homo sapiens] 82 6e-15
gi|150456471 doublecortin domain containing 2B [Homo sapiens] 65 7e-10
gi|239753110 PREDICTED: doublecortin domain-containing protein E... 62 8e-09
gi|239747673 PREDICTED: doublecortin domain-containing protein E... 62 8e-09
gi|239741542 PREDICTED: doublecortin domain-containing protein E... 62 8e-09
gi|71061468 centromere protein E [Homo sapiens] 41 0.011
gi|125490370 type I hair keratin KA36 [Homo sapiens] 39 0.055
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 39 0.072
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 39 0.072
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 39 0.072
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 39 0.072
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 39 0.072
gi|4759082 serum deprivation response protein [Homo sapiens] 38 0.094
gi|151301098 zinc finger, DBF-type containing 2 [Homo sapiens] 37 0.16
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)... 37 0.21
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)... 37 0.21
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)... 37 0.21
gi|47717112 zinc finger, FYVE domain containing 9 isoform 1 [Hom... 37 0.27
gi|47717106 zinc finger, FYVE domain containing 9 isoform 3 [Hom... 37 0.27
gi|6552337 zinc finger, FYVE domain containing 9 isoform 2 [Homo... 37 0.27
gi|239747116 PREDICTED: hypothetical protein XP_002343915 isofor... 36 0.47
>gi|5454016 retinitis pigmentosa RP1 protein [Homo sapiens]
Length = 2156
Score = 4312 bits (11184), Expect = 0.0
Identities = 2156/2156 (100%), Positives = 2156/2156 (100%)
Query: 1 MSDTPSTGFSIIHPTSSEGQVPPPRHLSLTHPVVAKRISFYKSGDPQFGGVRVVVNPRSF 60
MSDTPSTGFSIIHPTSSEGQVPPPRHLSLTHPVVAKRISFYKSGDPQFGGVRVVVNPRSF
Sbjct: 1 MSDTPSTGFSIIHPTSSEGQVPPPRHLSLTHPVVAKRISFYKSGDPQFGGVRVVVNPRSF 60
Query: 61 KSFDALLDNLSRKVPLPFGVRNISTPRGRHSITRLEELEDGESYLCSHGRKVQPVDLDKA 120
KSFDALLDNLSRKVPLPFGVRNISTPRGRHSITRLEELEDGESYLCSHGRKVQPVDLDKA
Sbjct: 61 KSFDALLDNLSRKVPLPFGVRNISTPRGRHSITRLEELEDGESYLCSHGRKVQPVDLDKA 120
Query: 121 RRRPRPWLSSRAISAHSPPHPVAVAAPGMPRPPRSLVVFRNGDPKTRRAVLLSRRVTQSF 180
RRRPRPWLSSRAISAHSPPHPVAVAAPGMPRPPRSLVVFRNGDPKTRRAVLLSRRVTQSF
Sbjct: 121 RRRPRPWLSSRAISAHSPPHPVAVAAPGMPRPPRSLVVFRNGDPKTRRAVLLSRRVTQSF 180
Query: 181 EAFLQHLTEVMQRPVVKLYATDGRRVPSLQAVILSSGAVVAAGREPFKPGNYDIQKYLLP 240
EAFLQHLTEVMQRPVVKLYATDGRRVPSLQAVILSSGAVVAAGREPFKPGNYDIQKYLLP
Sbjct: 181 EAFLQHLTEVMQRPVVKLYATDGRRVPSLQAVILSSGAVVAAGREPFKPGNYDIQKYLLP 240
Query: 241 ARLPGISQRVYPKGNAKSESRKISTHMSSSSRSQIYSVSSEKTHNNDCYLDYSFVPEKYL 300
ARLPGISQRVYPKGNAKSESRKISTHMSSSSRSQIYSVSSEKTHNNDCYLDYSFVPEKYL
Sbjct: 241 ARLPGISQRVYPKGNAKSESRKISTHMSSSSRSQIYSVSSEKTHNNDCYLDYSFVPEKYL 300
Query: 301 ALEKNDSQNLPIYPSEDDIEKSIIFNQDGTMTVEMKVRFRIKEEETIKWTTTVSKTGPSN 360
ALEKNDSQNLPIYPSEDDIEKSIIFNQDGTMTVEMKVRFRIKEEETIKWTTTVSKTGPSN
Sbjct: 301 ALEKNDSQNLPIYPSEDDIEKSIIFNQDGTMTVEMKVRFRIKEEETIKWTTTVSKTGPSN 360
Query: 361 NDEKSEMSFPGRTESRSSGLKLAACSFSADVSPMERSSNQEGSLAEEINIQMTDQVAETC 420
NDEKSEMSFPGRTESRSSGLKLAACSFSADVSPMERSSNQEGSLAEEINIQMTDQVAETC
Sbjct: 361 NDEKSEMSFPGRTESRSSGLKLAACSFSADVSPMERSSNQEGSLAEEINIQMTDQVAETC 420
Query: 421 SSASWENATVDTDIIQGTQDQAKHRFYRPPTPGLRRVRQKKSVIGSVTLVSETEVQEKMI 480
SSASWENATVDTDIIQGTQDQAKHRFYRPPTPGLRRVRQKKSVIGSVTLVSETEVQEKMI
Sbjct: 421 SSASWENATVDTDIIQGTQDQAKHRFYRPPTPGLRRVRQKKSVIGSVTLVSETEVQEKMI 480
Query: 481 GQFSYSEERESGENKSEYHMFTHSCSKMSSVSNKPVLVQINNNDQMEESSLERKKENSLL 540
GQFSYSEERESGENKSEYHMFTHSCSKMSSVSNKPVLVQINNNDQMEESSLERKKENSLL
Sbjct: 481 GQFSYSEERESGENKSEYHMFTHSCSKMSSVSNKPVLVQINNNDQMEESSLERKKENSLL 540
Query: 541 KSSAISAGVIEITSQKMLEMSHNNGLPSTISNNSIVEEDVVDCVVLDNKTGIKNFKTYGN 600
KSSAISAGVIEITSQKMLEMSHNNGLPSTISNNSIVEEDVVDCVVLDNKTGIKNFKTYGN
Sbjct: 541 KSSAISAGVIEITSQKMLEMSHNNGLPSTISNNSIVEEDVVDCVVLDNKTGIKNFKTYGN 600
Query: 601 TNDRFSPISADATHFSSNNSGTDKNISEAPASEASSTVTARIDRLINEFAQCGLTKLPKN 660
TNDRFSPISADATHFSSNNSGTDKNISEAPASEASSTVTARIDRLINEFAQCGLTKLPKN
Sbjct: 601 TNDRFSPISADATHFSSNNSGTDKNISEAPASEASSTVTARIDRLINEFAQCGLTKLPKN 660
Query: 661 EKKILSSVASKKKKKSRQQAINSRYQDGQLATKGILNKNERINTKGRITKEMIVQDSDSP 720
EKKILSSVASKKKKKSRQQAINSRYQDGQLATKGILNKNERINTKGRITKEMIVQDSDSP
Sbjct: 661 EKKILSSVASKKKKKSRQQAINSRYQDGQLATKGILNKNERINTKGRITKEMIVQDSDSP 720
Query: 721 LKGGILCEEDLQKSDTVIESNTFCSKSNLNSTISKNFHRNKLNTTQNSKVQGLLTKRKSR 780
LKGGILCEEDLQKSDTVIESNTFCSKSNLNSTISKNFHRNKLNTTQNSKVQGLLTKRKSR
Sbjct: 721 LKGGILCEEDLQKSDTVIESNTFCSKSNLNSTISKNFHRNKLNTTQNSKVQGLLTKRKSR 780
Query: 781 SLNKISLGAPKKREIGQRDKVFPHNESKYCKSTFENKSLFHVFNILEQKPKDFYAPQSQA 840
SLNKISLGAPKKREIGQRDKVFPHNESKYCKSTFENKSLFHVFNILEQKPKDFYAPQSQA
Sbjct: 781 SLNKISLGAPKKREIGQRDKVFPHNESKYCKSTFENKSLFHVFNILEQKPKDFYAPQSQA 840
Query: 841 EVASGYLRGMAKKSLVSKVTDSHITLKSQKKRKGDKVKASAILSKQHATTRANSLASLKK 900
EVASGYLRGMAKKSLVSKVTDSHITLKSQKKRKGDKVKASAILSKQHATTRANSLASLKK
Sbjct: 841 EVASGYLRGMAKKSLVSKVTDSHITLKSQKKRKGDKVKASAILSKQHATTRANSLASLKK 900
Query: 901 PDFPEAIAHHSIQNYIQSWLQNINPYPTLKPIKSAPVCRNETSVVNCSNNSFSGNDPHTN 960
PDFPEAIAHHSIQNYIQSWLQNINPYPTLKPIKSAPVCRNETSVVNCSNNSFSGNDPHTN
Sbjct: 901 PDFPEAIAHHSIQNYIQSWLQNINPYPTLKPIKSAPVCRNETSVVNCSNNSFSGNDPHTN 960
Query: 961 SGKISNFVMESNKHITKIAGLTGDNLCKEGDKSFIANDTGEEDLHETQVGSLNDAYLVPL 1020
SGKISNFVMESNKHITKIAGLTGDNLCKEGDKSFIANDTGEEDLHETQVGSLNDAYLVPL
Sbjct: 961 SGKISNFVMESNKHITKIAGLTGDNLCKEGDKSFIANDTGEEDLHETQVGSLNDAYLVPL 1020
Query: 1021 HEHCTLSQSAINDHNTKSHIAAEKSGPEKKLVYQEINLARKRQSVEAAIQVDPIEEETPK 1080
HEHCTLSQSAINDHNTKSHIAAEKSGPEKKLVYQEINLARKRQSVEAAIQVDPIEEETPK
Sbjct: 1021 HEHCTLSQSAINDHNTKSHIAAEKSGPEKKLVYQEINLARKRQSVEAAIQVDPIEEETPK 1080
Query: 1081 DLLPVLMLHQLQASVPGIHKTQNGVVQMPGSLAGVPFHSAICNSSTNLLLAWLLVLNLKG 1140
DLLPVLMLHQLQASVPGIHKTQNGVVQMPGSLAGVPFHSAICNSSTNLLLAWLLVLNLKG
Sbjct: 1081 DLLPVLMLHQLQASVPGIHKTQNGVVQMPGSLAGVPFHSAICNSSTNLLLAWLLVLNLKG 1140
Query: 1141 SMNSFCQVDAHKATNKSSETLALLEILKHIAITEEADDLKAAVANLVESTTSHFGLSEKE 1200
SMNSFCQVDAHKATNKSSETLALLEILKHIAITEEADDLKAAVANLVESTTSHFGLSEKE
Sbjct: 1141 SMNSFCQVDAHKATNKSSETLALLEILKHIAITEEADDLKAAVANLVESTTSHFGLSEKE 1200
Query: 1201 QDMVPIDLSANCSTVNIQSVPKCSENERTQGISSLDGGCSASEACAPEVCVLEVTCSPCE 1260
QDMVPIDLSANCSTVNIQSVPKCSENERTQGISSLDGGCSASEACAPEVCVLEVTCSPCE
Sbjct: 1201 QDMVPIDLSANCSTVNIQSVPKCSENERTQGISSLDGGCSASEACAPEVCVLEVTCSPCE 1260
Query: 1261 MCTVNKAYSPKETCNPSDTFFPSDGYGVDQTSMNKACFLGEVCSLTDTVFSDKACAQKEN 1320
MCTVNKAYSPKETCNPSDTFFPSDGYGVDQTSMNKACFLGEVCSLTDTVFSDKACAQKEN
Sbjct: 1261 MCTVNKAYSPKETCNPSDTFFPSDGYGVDQTSMNKACFLGEVCSLTDTVFSDKACAQKEN 1320
Query: 1321 HTYEGACPIDETYVPVNVCNTIDFLNSKENTYTDNLDSTEELERGDDIQKDLNILTDPEY 1380
HTYEGACPIDETYVPVNVCNTIDFLNSKENTYTDNLDSTEELERGDDIQKDLNILTDPEY
Sbjct: 1321 HTYEGACPIDETYVPVNVCNTIDFLNSKENTYTDNLDSTEELERGDDIQKDLNILTDPEY 1380
Query: 1381 KNGFNTLVSHQNVSNLSSCGLCLSEKEAELDKKHSSLDDFENCSLRKFQDENAYTSFDME 1440
KNGFNTLVSHQNVSNLSSCGLCLSEKEAELDKKHSSLDDFENCSLRKFQDENAYTSFDME
Sbjct: 1381 KNGFNTLVSHQNVSNLSSCGLCLSEKEAELDKKHSSLDDFENCSLRKFQDENAYTSFDME 1440
Query: 1441 EPRTSEEPGSITNSMTSSERNISELESFEELENHDTDIFNTVVNGGEQATEELIQEEVEA 1500
EPRTSEEPGSITNSMTSSERNISELESFEELENHDTDIFNTVVNGGEQATEELIQEEVEA
Sbjct: 1441 EPRTSEEPGSITNSMTSSERNISELESFEELENHDTDIFNTVVNGGEQATEELIQEEVEA 1500
Query: 1501 SKTLELIDISSKNIMEEKRMNGIIYEIISKRLATPPSLDFCYDSKQNSEKETNEGETKMV 1560
SKTLELIDISSKNIMEEKRMNGIIYEIISKRLATPPSLDFCYDSKQNSEKETNEGETKMV
Sbjct: 1501 SKTLELIDISSKNIMEEKRMNGIIYEIISKRLATPPSLDFCYDSKQNSEKETNEGETKMV 1560
Query: 1561 KMMVKTMETGSYSESSPDLKKCIKSPVTSDWSDYRPDSDSEQPYKTSSDDPNDSGELTQE 1620
KMMVKTMETGSYSESSPDLKKCIKSPVTSDWSDYRPDSDSEQPYKTSSDDPNDSGELTQE
Sbjct: 1561 KMMVKTMETGSYSESSPDLKKCIKSPVTSDWSDYRPDSDSEQPYKTSSDDPNDSGELTQE 1620
Query: 1621 KEYNIGFVKRAIEKLYGKADIIKPSFFPGSTRKSQVCPYNSVEFQCSRKASLYDSEGQSF 1680
KEYNIGFVKRAIEKLYGKADIIKPSFFPGSTRKSQVCPYNSVEFQCSRKASLYDSEGQSF
Sbjct: 1621 KEYNIGFVKRAIEKLYGKADIIKPSFFPGSTRKSQVCPYNSVEFQCSRKASLYDSEGQSF 1680
Query: 1681 GSSEQVSSSSSMLQEFQEERQDKCDVSAVRDNYCRGDIVEPGTKQNDDSRILTDIEEGVL 1740
GSSEQVSSSSSMLQEFQEERQDKCDVSAVRDNYCRGDIVEPGTKQNDDSRILTDIEEGVL
Sbjct: 1681 GSSEQVSSSSSMLQEFQEERQDKCDVSAVRDNYCRGDIVEPGTKQNDDSRILTDIEEGVL 1740
Query: 1741 IDKGKWLLKENHLLRMSSENPGMCGNADTTSVDTLLDNNSSEVPYSHFGNLAPGPTMDEL 1800
IDKGKWLLKENHLLRMSSENPGMCGNADTTSVDTLLDNNSSEVPYSHFGNLAPGPTMDEL
Sbjct: 1741 IDKGKWLLKENHLLRMSSENPGMCGNADTTSVDTLLDNNSSEVPYSHFGNLAPGPTMDEL 1800
Query: 1801 SSSELEELTQPLELKCNYFNMPHGSDSEPFHEDLLDVRNETCAKERIANHHTEEKGSHQS 1860
SSSELEELTQPLELKCNYFNMPHGSDSEPFHEDLLDVRNETCAKERIANHHTEEKGSHQS
Sbjct: 1801 SSSELEELTQPLELKCNYFNMPHGSDSEPFHEDLLDVRNETCAKERIANHHTEEKGSHQS 1860
Query: 1861 ERVCTSVTHSFISAGNKVYPVSDDAIKNQPLPGSNMIHGTLQEADSLDKLYALCGQHCPI 1920
ERVCTSVTHSFISAGNKVYPVSDDAIKNQPLPGSNMIHGTLQEADSLDKLYALCGQHCPI
Sbjct: 1861 ERVCTSVTHSFISAGNKVYPVSDDAIKNQPLPGSNMIHGTLQEADSLDKLYALCGQHCPI 1920
Query: 1921 LTVIIQPMNEEDRGFAYRKESDIENFLGFYLWMKIHPYLLQTDKNVFREENNKASMRQNL 1980
LTVIIQPMNEEDRGFAYRKESDIENFLGFYLWMKIHPYLLQTDKNVFREENNKASMRQNL
Sbjct: 1921 LTVIIQPMNEEDRGFAYRKESDIENFLGFYLWMKIHPYLLQTDKNVFREENNKASMRQNL 1980
Query: 1981 IDNAIGDIFDQFYFSNTFDLMGKRRKQKRINFLGLEEEGNLKKFQPDLKERFCMNFLHTS 2040
IDNAIGDIFDQFYFSNTFDLMGKRRKQKRINFLGLEEEGNLKKFQPDLKERFCMNFLHTS
Sbjct: 1981 IDNAIGDIFDQFYFSNTFDLMGKRRKQKRINFLGLEEEGNLKKFQPDLKERFCMNFLHTS 2040
Query: 2041 LLVVGNVDSNTQDLSGQTNEIFKAVDENNNLLNNRFQGSRTNLNQVVRENINCHYFFEML 2100
LLVVGNVDSNTQDLSGQTNEIFKAVDENNNLLNNRFQGSRTNLNQVVRENINCHYFFEML
Sbjct: 2041 LLVVGNVDSNTQDLSGQTNEIFKAVDENNNLLNNRFQGSRTNLNQVVRENINCHYFFEML 2100
Query: 2101 GQACLLDICQVETSLNISNRNILELCMFEGENLFIWEEEDILNLTDLESSREQEDL 2156
GQACLLDICQVETSLNISNRNILELCMFEGENLFIWEEEDILNLTDLESSREQEDL
Sbjct: 2101 GQACLLDICQVETSLNISNRNILELCMFEGENLFIWEEEDILNLTDLESSREQEDL 2156
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 172 bits (437), Expect = 2e-42
Identities = 107/328 (32%), Positives = 176/328 (53%), Gaps = 8/328 (2%)
Query: 28 SLTHPVVAKRISFYKSGDPQFGGVRVVVNPRSFKSFDALLDNLSRKVPLPFGVRNISTPR 87
S+T AK+I+F K GDP+F GVR+ V+ R+FK+F AL+D LS++VPL FGVR+++TPR
Sbjct: 26 SVTKVTPAKKITFLKRGDPRFAGVRLAVHQRAFKTFSALMDELSQRVPLSFGVRSVTTPR 85
Query: 88 GRHSITRLEELEDGESYLCSHGRKVQPVDLDKARRRPRPWLSSRAISAHSPPHPVAVAAP 147
G HS++ LE+LEDG YLCS + + + P P ++
Sbjct: 86 GLHSLSALEQLEDGGCYLCSDKKPPKTPSGPGRPQERNPTAQQLRDVEGQREAPGTSSSR 145
Query: 148 GMPRPPRSLVVFRNGDPKTRRAVLLSRRVTQSFEAFLQHLTEVMQRPVVKLYATDGRRVP 207
+ PR +++ +N DP+ ++ V+LS R T++ AFL +++++ PV +LY T G++V
Sbjct: 146 KSLKTPRRILLIKNMDPRLQQTVVLSHRNTRNLAAFLGKASDLLRFPVKQLYTTSGKKVD 205
Query: 208 SLQAVILSSGAVVAAGREPFKPGNYDIQKYLLPARLPGISQRVYPKGNAKSESRKISTHM 267
SLQA++ S +V AG E F+ + L G++ R K + K S
Sbjct: 206 SLQALLHSPSVLVCAGHEAFRTPAMKNARRSEAETLSGLTSR--NKNGSWGPKTKPSVIH 263
Query: 268 SSSSRSQIYSVSSEKTHNNDCYLDYSFVPEKYLALEKNDSQNLPIYPSEDDIEKSIIFNQ 327
S S + +N P + +Q+ P+ + DD++K + N+
Sbjct: 264 SRSPPGSTPRLPERPGPSNP-----PVGPAPGRHPQDTPAQSGPLV-AGDDMKKKVRMNE 317
Query: 328 DGTMTVEMKVRFRIKEEETIKWTTTVSK 355
DG+++VEMKVRF + E+T+ W+ + +
Sbjct: 318 DGSLSVEMKVRFHLVGEDTLLWSRRMGR 345
>gi|30181244 doublecortin isoform c [Homo sapiens]
Length = 360
Score = 95.9 bits (237), Expect = 4e-19
Identities = 68/215 (31%), Positives = 108/215 (50%), Gaps = 15/215 (6%)
Query: 28 SLTHPVVAKRISFYKSGDPQFGGVRVVVNPRSFKSFDALLDNLSRK----VPLPFGVRNI 83
+L++ AK++ FY++GD F G+ V+ F+SFDALL +L+R + LP GVR I
Sbjct: 45 ALSNEKKAKKVRFYRNGDRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLPQGVRYI 104
Query: 84 STPRGRHSITRLEELEDGESYLCSHGRKVQPVDLDKARRRPRPWLSSRAISAHSPPHPVA 143
T G I ++ELE+GESY+CS + V+ K P ++ + + P +A
Sbjct: 105 YTIDGSRKIGSMDELEEGESYVCSSDNFFKKVEYTK-NVNPNWSVNVKTSANMKAPQSLA 163
Query: 144 VAAPGMPRP------PRSLVVFRNG-DPKTRRAVLLSRRVTQSFEAFLQHLTEVMQRP-- 194
+ R P+ + + R+G P+ VLL+++ SFE L +TE ++
Sbjct: 164 SSNSAQARENKDFVRPKLVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIKLETG 223
Query: 195 -VVKLYATDGRRVPSLQAVILSSGAVVAAGREPFK 228
V KLY DG++V L +A G E F+
Sbjct: 224 VVKKLYTLDGKQVTCLHDFFGDDDVFIACGPEKFR 258
>gi|30181242 doublecortin isoform b [Homo sapiens]
Length = 365
Score = 95.9 bits (237), Expect = 4e-19
Identities = 68/215 (31%), Positives = 108/215 (50%), Gaps = 15/215 (6%)
Query: 28 SLTHPVVAKRISFYKSGDPQFGGVRVVVNPRSFKSFDALLDNLSRK----VPLPFGVRNI 83
+L++ AK++ FY++GD F G+ V+ F+SFDALL +L+R + LP GVR I
Sbjct: 45 ALSNEKKAKKVRFYRNGDRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLPQGVRYI 104
Query: 84 STPRGRHSITRLEELEDGESYLCSHGRKVQPVDLDKARRRPRPWLSSRAISAHSPPHPVA 143
T G I ++ELE+GESY+CS + V+ K P ++ + + P +A
Sbjct: 105 YTIDGSRKIGSMDELEEGESYVCSSDNFFKKVEYTK-NVNPNWSVNVKTSANMKAPQSLA 163
Query: 144 VAAPGMPRP------PRSLVVFRNG-DPKTRRAVLLSRRVTQSFEAFLQHLTEVMQRP-- 194
+ R P+ + + R+G P+ VLL+++ SFE L +TE ++
Sbjct: 164 SSNSAQARENKDFVRPKLVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIKLETG 223
Query: 195 -VVKLYATDGRRVPSLQAVILSSGAVVAAGREPFK 228
V KLY DG++V L +A G E F+
Sbjct: 224 VVKKLYTLDGKQVTCLHDFFGDDDVFIACGPEKFR 258
>gi|30181240 doublecortin isoform c [Homo sapiens]
Length = 360
Score = 95.9 bits (237), Expect = 4e-19
Identities = 68/215 (31%), Positives = 108/215 (50%), Gaps = 15/215 (6%)
Query: 28 SLTHPVVAKRISFYKSGDPQFGGVRVVVNPRSFKSFDALLDNLSRK----VPLPFGVRNI 83
+L++ AK++ FY++GD F G+ V+ F+SFDALL +L+R + LP GVR I
Sbjct: 45 ALSNEKKAKKVRFYRNGDRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLPQGVRYI 104
Query: 84 STPRGRHSITRLEELEDGESYLCSHGRKVQPVDLDKARRRPRPWLSSRAISAHSPPHPVA 143
T G I ++ELE+GESY+CS + V+ K P ++ + + P +A
Sbjct: 105 YTIDGSRKIGSMDELEEGESYVCSSDNFFKKVEYTK-NVNPNWSVNVKTSANMKAPQSLA 163
Query: 144 VAAPGMPRP------PRSLVVFRNG-DPKTRRAVLLSRRVTQSFEAFLQHLTEVMQRP-- 194
+ R P+ + + R+G P+ VLL+++ SFE L +TE ++
Sbjct: 164 SSNSAQARENKDFVRPKLVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIKLETG 223
Query: 195 -VVKLYATDGRRVPSLQAVILSSGAVVAAGREPFK 228
V KLY DG++V L +A G E F+
Sbjct: 224 VVKKLYTLDGKQVTCLHDFFGDDDVFIACGPEKFR 258
>gi|30181246 doublecortin isoform a [Homo sapiens]
Length = 441
Score = 95.9 bits (237), Expect = 4e-19
Identities = 68/215 (31%), Positives = 108/215 (50%), Gaps = 15/215 (6%)
Query: 28 SLTHPVVAKRISFYKSGDPQFGGVRVVVNPRSFKSFDALLDNLSRK----VPLPFGVRNI 83
+L++ AK++ FY++GD F G+ V+ F+SFDALL +L+R + LP GVR I
Sbjct: 126 ALSNEKKAKKVRFYRNGDRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLPQGVRYI 185
Query: 84 STPRGRHSITRLEELEDGESYLCSHGRKVQPVDLDKARRRPRPWLSSRAISAHSPPHPVA 143
T G I ++ELE+GESY+CS + V+ K P ++ + + P +A
Sbjct: 186 YTIDGSRKIGSMDELEEGESYVCSSDNFFKKVEYTK-NVNPNWSVNVKTSANMKAPQSLA 244
Query: 144 VAAPGMPRP------PRSLVVFRNG-DPKTRRAVLLSRRVTQSFEAFLQHLTEVMQRP-- 194
+ R P+ + + R+G P+ VLL+++ SFE L +TE ++
Sbjct: 245 SSNSAQARENKDFVRPKLVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIKLETG 304
Query: 195 -VVKLYATDGRRVPSLQAVILSSGAVVAAGREPFK 228
V KLY DG++V L +A G E F+
Sbjct: 305 VVKKLYTLDGKQVTCLHDFFGDDDVFIACGPEKFR 339
>gi|156713428 doublecortin-like kinase 2 isoform a [Homo sapiens]
Length = 766
Score = 94.4 bits (233), Expect = 1e-18
Identities = 93/344 (27%), Positives = 145/344 (42%), Gaps = 34/344 (9%)
Query: 6 STGFSIIHPTSSEGQVPPPRHLS------------LTHPVVAKRISFYKSGDPQFGGVRV 53
S+G S G +P P H + L+ AK+ FY++GD F G+
Sbjct: 30 SSGGSSSSGPKGNGLIPSPAHSAHCSFYRTRTLQALSSEKKAKKARFYRNGDRYFKGLVF 89
Query: 54 VVNPRSFKSFDALLDNLSRK----VPLPFGVRNISTPRGRHSITRLEELEDGESYLCSHG 109
++ F+SFDALL L+R V LP GVR I T G +T L+EL +GESY+C+
Sbjct: 90 AISSDRFRSFDALLIELTRSLSDNVNLPQGVRTIYTIDGSRKVTSLDELLEGESYVCASN 149
Query: 110 RKVQPVDLDKARRRPRPWL------SSRAISAHSPPHPVAVAAPGMPRPPRSLVVFRNGD 163
+ VD K P W +SRA++A S + +P V+
Sbjct: 150 EPFRKVDYTK-NINPN-WSVNIKGGTSRALAAASSVKSEVKESKDFIKPKLVTVIRSGVK 207
Query: 164 PKTRRAVLLSRRVTQSFEAFLQHLTEVMQRP---VVKLYATDGRRVPSLQAVILSSGAVV 220
P+ +LL+++ SFE L +TE ++ V +L DG++V LQ +
Sbjct: 208 PRKAVRILLNKKTAHSFEQVLTDITEAIKLDSGVVKRLCTLDGKQVTCLQDFFGDDDVFI 267
Query: 221 AAGREPFKPGNYDI-----QKYLLPARLPGISQRVYPKGNAKSESR--KISTHMSSSSRS 273
A G E F+ D + +L + S Y + SR K ++ + S
Sbjct: 268 ACGPEKFRYAQDDFVLDHSECRVLKSSYSRSSAVKYSGSKSPGPSRRSKSPASVNGTPSS 327
Query: 274 QIYSVSSEKTHNNDCYLDYSFVPEKYLALEKNDSQNLPIYPSED 317
Q+ + S K+ ++ SF K ++ S N+ P D
Sbjct: 328 QLSTPKSTKSSSSSPTSPGSFRGLKQISAHGRSSSNVNGGPELD 371
>gi|156713430 doublecortin-like kinase 2 isoform b [Homo sapiens]
Length = 765
Score = 93.6 bits (231), Expect = 2e-18
Identities = 84/293 (28%), Positives = 128/293 (43%), Gaps = 30/293 (10%)
Query: 6 STGFSIIHPTSSEGQVPPPRHLS------------LTHPVVAKRISFYKSGDPQFGGVRV 53
S+G S G +P P H + L+ AK+ FY++GD F G+
Sbjct: 30 SSGGSSSSGPKGNGLIPSPAHSAHCSFYRTRTLQALSSEKKAKKARFYRNGDRYFKGLVF 89
Query: 54 VVNPRSFKSFDALLDNLSRK----VPLPFGVRNISTPRGRHSITRLEELEDGESYLCSHG 109
++ F+SFDALL L+R V LP GVR I T G +T L+EL +GESY+C+
Sbjct: 90 AISSDRFRSFDALLIELTRSLSDNVNLPQGVRTIYTIDGSRKVTSLDELLEGESYVCASN 149
Query: 110 RKVQPVDLDKARRRPRPWL------SSRAISAHSPPHPVAVAAPGMPRPPRSLVVFRNGD 163
+ VD K P W +SRA++A S + +P V+
Sbjct: 150 EPFRKVDYTK-NINPN-WSVNIKGGTSRALAAASSVKSEVKESKDFIKPKLVTVIRSGVK 207
Query: 164 PKTRRAVLLSRRVTQSFEAFLQHLTEVMQRP---VVKLYATDGRRVPSLQAVILSSGAVV 220
P+ +LL+++ SFE L +TE ++ V +L DG++V LQ +
Sbjct: 208 PRKAVRILLNKKTAHSFEQVLTDITEAIKLDSGVVKRLCTLDGKQVTCLQDFFGDDDVFI 267
Query: 221 AAGREPFKPGNYDIQKYLLPARLPGISQRVYPKGNAKSESRKISTHMSSSSRS 273
A G E F+ Y ++L + + Y + +A S S S S+S
Sbjct: 268 ACGPEKFR---YAQDDFVLDHSECRVLKSSYSRSSAVKYSGSKSPGPSRRSKS 317
>gi|4758128 doublecortin-like kinase 1 [Homo sapiens]
Length = 729
Score = 90.5 bits (223), Expect = 2e-17
Identities = 95/389 (24%), Positives = 157/389 (40%), Gaps = 45/389 (11%)
Query: 35 AKRISFYKSGDPQFGGVRVVVNPRSFKSFDALLDNLSR----KVPLPFGVRNISTPRGRH 90
AK++ FY++GD F G+ ++P F+SF+ALL +L+R V LP GVR I T G
Sbjct: 56 AKKVRFYRNGDRYFKGIVYAISPDRFRSFEALLADLTRTLSDNVNLPQGVRTIYTIDGLK 115
Query: 91 SITRLEELEDGESYLCSHGRKVQPVDLDKARRRPRP-WLSSRAISAHSPPHPVAVAAPGM 149
I+ L++L +GESY+C ++P + + P W + ++ S A G
Sbjct: 116 KISSLDQLVEGESYVCG---SIEPFKKLEYTKNVNPNWSVNVKTTSASRAVSSLATAKGS 172
Query: 150 PRP---------PRSLVVFRNG-DPKTRRAVLLSRRVTQSFEAFLQHLTEVMQRP---VV 196
P P+ + + R+G P+ +LL+++ SFE L +T+ ++ V
Sbjct: 173 PSEVRENKDFIRPKLVTIIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGVVK 232
Query: 197 KLYATDGRRVPSLQAVILSSGAVVAAGREPFKPGNYDIQKYLLPARLPGISQRVYPKGNA 256
+LY DG++V LQ +A G E F+ Y L + + Y K
Sbjct: 233 RLYTLDGKQVMCLQDFFGDDDIFIACGPEKFR---YQDDFLLDESECRVVKSTSYTK--I 287
Query: 257 KSESRKISTHMSSSSRSQIYSVSSEKTHNNDCYLDYSFVPEKYLALEKNDSQNLPIYPSE 316
S SR+ +T SR S+ + P L+ ++ P S
Sbjct: 288 ASSSRRSTTKSPGPSRRSKSPASTSSVNG---------TPGSQLSTPRSGKSPSPSPTSP 338
Query: 317 DDIEKSIIFNQDGTMTVEMKVRFRIKEEETIKWTTTVSKTGPSNNDEKSEMSFPGR-TES 375
+ K G+ T + +E GP + P TE
Sbjct: 339 GSLRKQRSSQHGGSSTSLASTKVCSSMDE---------NDGPGEEVSEEGFQIPATITER 389
Query: 376 RSSGLKLAACSFSADVSPMERSSNQEGSL 404
G + +F+ +ERS+ +E +L
Sbjct: 390 YKVGRTIGDGNFAVVKECVERSTAREYAL 418
>gi|117938307 doublecortin domain containing 2 [Homo sapiens]
Length = 476
Score = 82.0 bits (201), Expect = 6e-15
Identities = 63/214 (29%), Positives = 110/214 (51%), Gaps = 14/214 (6%)
Query: 25 RHLSLTHPVVAKRISFYKSGDPQFGGVRVVVNPRSFKSFDALLDNLSRKVPLPFG-VRNI 83
R L+ PVV K + Y++GDP + G RVV++ + SF+ L ++ V PFG VRNI
Sbjct: 7 RSSHLSQPVV-KSVLVYRNGDPFYAGRRVVIHEKKVSSFEVFLKEVTGGVQAPFGAVRNI 65
Query: 84 STPRGRHSITRLEELEDGESYLCSHG---RKVQPVDLDKARRRPRPWLSSRAISAHSPPH 140
TPR H I +L++++ G +Y+ +K+ +D+ + ++RP +++
Sbjct: 66 YTPRTGHRIRKLDQIQSGGNYVAGGQEAFKKLNYLDIGEIKKRPMEVVNTEVKPVIHSRI 125
Query: 141 PVAVAAPGMPRPPRSLVVFRNGD---PKTRRAVLLSRRVTQSFEAFLQHLTE---VMQRP 194
V+ + P ++ + NGD P +R +L+ R+ ++ LQ +TE +
Sbjct: 126 NVSARFRKPLQEPCTIFLIANGDLINPASR--LLIPRKTLNQWDHVLQMVTEKITLRSGA 183
Query: 195 VVKLYATDGRRVPSLQAVILSSGAVVAAGREPFK 228
V +LY +G+ V S A + + VA GR+ FK
Sbjct: 184 VHRLYTLEGKLVES-GAELENGQFYVAVGRDKFK 216
>gi|150456471 doublecortin domain containing 2B [Homo sapiens]
Length = 349
Score = 65.1 bits (157), Expect = 7e-10
Identities = 61/207 (29%), Positives = 96/207 (46%), Gaps = 21/207 (10%)
Query: 35 AKRISFYKSGDPQFGGVRVVVNPRSFKSFDALLDNLSRKVPLPFGVRNISTPRGRHSITR 94
AKR+ Y++GDP F G ++VV R F + +A L ++ V P VR + TP H +T
Sbjct: 8 AKRVVVYRNGDPFFPGSQLVVTQRRFPTMEAFLCEVTSAVQAPLAVRALYTPCHGHPVTN 67
Query: 95 LEELEDGESYLCSHGRKVQPVDLDKARRRPRPWLSSRAISAHSPP--HPVAVAAPGMPRP 152
L +L++ Y+ + + + R + S R PP + A G P
Sbjct: 68 LADLKNRGQYVAAGFERFHKLHYLPHRGKDPGGKSCR---LQGPPVTRHLCDGAIGRQLP 124
Query: 153 ---PRSLVVFRNGD-PKTRRAVLLSRRVTQSFEAFLQHLTEVMQRPVVKLYATDGRRVPS 208
P + VFRNGD ++ LS+ +Q +E L+ LTE VKL + ++ +
Sbjct: 125 AGAPSYIHVFRNGDLVSPPFSLKLSQAASQDWETVLKLLTE-----KVKLQSGAVCKLCT 179
Query: 209 LQAVILSSGA-------VVAAGREPFK 228
L+ + LS+G VA G + FK
Sbjct: 180 LEGLPLSAGKELVTGHYYVAVGEDEFK 206
>gi|239753110 PREDICTED: doublecortin domain-containing protein
ENSP00000382097-like [Homo sapiens]
Length = 530
Score = 61.6 bits (148), Expect = 8e-09
Identities = 41/132 (31%), Positives = 65/132 (49%), Gaps = 6/132 (4%)
Query: 35 AKRISFYKSGDPQFGGVRVVVNPRSFKSFDALLDNLSRKVPLPFGVRNISTPRGRHSITR 94
AK I Y++GDP + G + V++ R +F+ALL+ L+ +V +PFGVR + TP H +
Sbjct: 85 AKTIVVYRNGDPFYVGKKFVLSRRRAATFEALLEQLTEQVDVPFGVRRLFTPTRGHRVLG 144
Query: 95 LEELEDGESYLCSHGRKVQPVDLDKARRRPRPWLSSRAISAHSPPHPVAVAAPG----MP 150
L+ L+ G Y+ + + + +LD PR R + P + P
Sbjct: 145 LDALQAGGKYVAAGRERFK--ELDYIHIVPRKPAKIRKLKEIKPVVHCDINVPSKWQTYH 202
Query: 151 RPPRSLVVFRNG 162
R R + VF NG
Sbjct: 203 RISRHINVFTNG 214
Score = 56.6 bits (135), Expect = 3e-07
Identities = 40/92 (43%), Positives = 55/92 (59%), Gaps = 5/92 (5%)
Query: 145 AAPGMPRPPRSLVVFRNGDP-KTRRAVLLSRRVTQSFEAFLQHLTEVMQRP--VVKLYA- 200
+AP P +++VV+RNGDP + +LSRR +FEA L+ LTE + P V +L+
Sbjct: 77 SAPVDTTPAKTIVVYRNGDPFYVGKKFVLSRRRAATFEALLEQLTEQVDVPFGVRRLFTP 136
Query: 201 TDGRRVPSLQAVILSSGAVVAAGREPFKPGNY 232
T G RV L A + + G VAAGRE FK +Y
Sbjct: 137 TRGHRVLGLDA-LQAGGKYVAAGRERFKELDY 167
>gi|239747673 PREDICTED: doublecortin domain-containing protein
ENSP00000382097-like [Homo sapiens]
Length = 714
Score = 61.6 bits (148), Expect = 8e-09
Identities = 41/132 (31%), Positives = 65/132 (49%), Gaps = 6/132 (4%)
Query: 35 AKRISFYKSGDPQFGGVRVVVNPRSFKSFDALLDNLSRKVPLPFGVRNISTPRGRHSITR 94
AK I Y++GDP + G + V++ R +F+ALL+ L+ +V +PFGVR + TP H +
Sbjct: 191 AKTIVVYRNGDPFYVGKKFVLSRRRAATFEALLEQLTEQVDVPFGVRRLFTPTRGHRVLG 250
Query: 95 LEELEDGESYLCSHGRKVQPVDLDKARRRPRPWLSSRAISAHSPPHPVAVAAPG----MP 150
L+ L+ G Y+ + + + +LD PR R + P + P
Sbjct: 251 LDALQAGGKYVAAGRERFK--ELDYIHIVPRKPAKIRKLKEIKPVVHCDINVPSKWQTYH 308
Query: 151 RPPRSLVVFRNG 162
R R + VF NG
Sbjct: 309 RISRHINVFTNG 320
Score = 56.6 bits (135), Expect = 3e-07
Identities = 40/92 (43%), Positives = 55/92 (59%), Gaps = 5/92 (5%)
Query: 145 AAPGMPRPPRSLVVFRNGDP-KTRRAVLLSRRVTQSFEAFLQHLTEVMQRP--VVKLYA- 200
+AP P +++VV+RNGDP + +LSRR +FEA L+ LTE + P V +L+
Sbjct: 183 SAPVDTTPAKTIVVYRNGDPFYVGKKFVLSRRRAATFEALLEQLTEQVDVPFGVRRLFTP 242
Query: 201 TDGRRVPSLQAVILSSGAVVAAGREPFKPGNY 232
T G RV L A + + G VAAGRE FK +Y
Sbjct: 243 TRGHRVLGLDA-LQAGGKYVAAGRERFKELDY 273
>gi|239741542 PREDICTED: doublecortin domain-containing protein
ENSP00000382097-like [Homo sapiens]
Length = 510
Score = 61.6 bits (148), Expect = 8e-09
Identities = 41/132 (31%), Positives = 65/132 (49%), Gaps = 6/132 (4%)
Query: 35 AKRISFYKSGDPQFGGVRVVVNPRSFKSFDALLDNLSRKVPLPFGVRNISTPRGRHSITR 94
AK I Y++GDP + G + V++ R +F+ALL+ L+ +V +PFGVR + TP H +
Sbjct: 191 AKTIVVYRNGDPFYVGKKFVLSRRRAATFEALLEQLTEQVDVPFGVRRLFTPTRGHRVLG 250
Query: 95 LEELEDGESYLCSHGRKVQPVDLDKARRRPRPWLSSRAISAHSPPHPVAVAAPG----MP 150
L+ L+ G Y+ + + + +LD PR R + P + P
Sbjct: 251 LDALQAGGKYVAAGRERFK--ELDYIHIVPRKPAKIRKLKEIKPVVHCDINVPSKWQTYH 308
Query: 151 RPPRSLVVFRNG 162
R R + VF NG
Sbjct: 309 RISRHINVFTNG 320
Score = 56.6 bits (135), Expect = 3e-07
Identities = 40/92 (43%), Positives = 55/92 (59%), Gaps = 5/92 (5%)
Query: 145 AAPGMPRPPRSLVVFRNGDP-KTRRAVLLSRRVTQSFEAFLQHLTEVMQRP--VVKLYA- 200
+AP P +++VV+RNGDP + +LSRR +FEA L+ LTE + P V +L+
Sbjct: 183 SAPVDTTPAKTIVVYRNGDPFYVGKKFVLSRRRAATFEALLEQLTEQVDVPFGVRRLFTP 242
Query: 201 TDGRRVPSLQAVILSSGAVVAAGREPFKPGNY 232
T G RV L A + + G VAAGRE FK +Y
Sbjct: 243 TRGHRVLGLDA-LQAGGKYVAAGRERFKELDY 273
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 41.2 bits (95), Expect = 0.011
Identities = 47/216 (21%), Positives = 99/216 (45%), Gaps = 24/216 (11%)
Query: 631 ASEASSTVTARIDRL--INEFAQCGLTKLPKNEKKILSSVASKKKKKSRQQAINSRYQDG 688
+ E ++T D L I E + +L ++ ++ L+ + + K+ +Q++N + +D
Sbjct: 1340 SQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQ--EQSLNMKEKDN 1397
Query: 689 QLATKGILNKNERINTKG----RITKEMI-----VQDSDSPLKGGILCEEDLQKSDTVIE 739
+ T I+++ E+ K RI EM+ +Q+S +K ++DLQ+ V++
Sbjct: 1398 E--TTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQ 1455
Query: 740 SNTFCSKSNLNSTISKNFHRNKLNTTQNSKVQGLLTKRKSRSLNKISLG-APKKREIGQR 798
S + K N+ ++K+ L T + KV K + ++N++ + + K+ EI
Sbjct: 1456 SESDQLKENIKEIVAKH-----LETEEELKVAHCCLKEQEETINELRVNLSEKETEISTI 1510
Query: 799 DKVFPHNESKY---CKSTFENKSLFHVFNILEQKPK 831
K K + +E + F++ I E + K
Sbjct: 1511 QKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEK 1546
Score = 34.3 bits (77), Expect = 1.4
Identities = 81/439 (18%), Positives = 172/439 (39%), Gaps = 33/439 (7%)
Query: 372 RTESRSSGLKLAACSFSADVSPMERSS--NQEGSLAEEI-NIQMTDQVAETCSSASWENA 428
RTE LKL + + +ER + +QE L EI N++ + AE +
Sbjct: 518 RTEKEEMELKLKEKNDLDEFEALERKTKKDQEMQLIHEISNLKNLVKHAEVYNQDLENEL 577
Query: 429 TVDTDIIQGTQDQAKHRFYRPPTPGLRRVRQKKSVIGSVTLVSETEVQEKMIGQ---FSY 485
+ ++++ +DQ K + L ++ S S+ + + + ++ + +
Sbjct: 578 SSKVELLREKEDQIKKLQEYIDSQKLENIKMDLSY--SLESIEDPKQMKQTLFDAETVAL 635
Query: 486 SEERESGENKSEYHMFTHSCSKMSSVSNKPVLVQINNNDQMEESSLERKKENSLLKSSAI 545
+RES +SE ++++ Q+ N+ Q+ +S LE KK+ + +
Sbjct: 636 DAKRESAFLRSENLELKEKMKELATTYK-----QMENDIQLYQSQLEAKKKMQVDLEKEL 690
Query: 546 SAGVIEITSQKMLEMSHNNGLPSTISNNSIVEEDVVDCVVLDNKTGIKNFKTYGNTNDRF 605
+ EIT L + +P + N +E + D NK +N
Sbjct: 691 QSAFNEITKLTSLI---DGKVPKDLLCNLELEGKITDLQKELNKEVEENEALREEVI--- 744
Query: 606 SPISADATHFSSNNSGTDKNISEAPASEASSTVTARIDRLINEFA------QCGLTKLPK 659
+ ++ S K I + SE +T+ D+L +E Q L ++ K
Sbjct: 745 --LLSELKSLPSEVERLRKEIQDK--SEELHIITSEKDKLFSEVVHKESRVQGLLEEIGK 800
Query: 660 NEKKILSSVASKKKKKSRQQAINSRYQDGQLATKGILNKNERINTK-GRITKEMIVQDSD 718
+ + ++ ++ K Q + + D + K +L +NER+N + ++KE Q D
Sbjct: 801 TKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKE--AQKFD 858
Query: 719 SPLKGGILCEEDLQKSDTVIESNTFCSKSNLNSTISKNFHRNKLNTTQNSKVQGLLTKRK 778
S L G + E + + ++ + N + + + + L+T++
Sbjct: 859 SSL-GALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKL 917
Query: 779 SRSLNKISLGAPKKREIGQ 797
++L ++ +K ++ Q
Sbjct: 918 QQTLEEVKTLTQEKDDLKQ 936
>gi|125490370 type I hair keratin KA36 [Homo sapiens]
Length = 431
Score = 38.9 bits (89), Expect = 0.055
Identities = 50/194 (25%), Positives = 75/194 (38%), Gaps = 32/194 (16%)
Query: 1239 CSASEACAPEVCVLEVTCSPCEMCTVNKAYSPKETCNPSDTFFPSDGYGVDQTSMNKACF 1298
CS++ C+PE C C+P C+V A P TC S PS F
Sbjct: 5 CSSTH-CSPESCGTASGCAPASSCSVETACLP-GTCATSRCQTPS--------------F 48
Query: 1299 LGEVCSLTDTVFSDKACAQKENHTYEGACP-IDETYVPVNVCNTIDFLNSKENTYTDNLD 1357
L LT + + G C ++ N T+ FLN + +Y + +
Sbjct: 49 LSRSRGLTGCLLPCYFTGSCNSPCLVGNCAWCEDGVFTSNEKETMQFLNDRLASYLEKVR 108
Query: 1358 STE----ELERGDDIQKDLNI-LTDPEYKNGFNTLVSHQNVSNLSSCGLCL----SEKEA 1408
S E ELE Q + +I + P+Y+ FNT + +L LC S
Sbjct: 109 SLEETNAELESRIQEQCEQDIPMVCPDYQRYFNT------IEDLQQKILCTKAENSRLAV 162
Query: 1409 ELDKKHSSLDDFEN 1422
+LD + DDF++
Sbjct: 163 QLDNCKLATDDFKS 176
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 38.5 bits (88), Expect = 0.072
Identities = 67/394 (17%), Positives = 139/394 (35%), Gaps = 18/394 (4%)
Query: 1346 NSKENTYTDNLDSTEELERGDDIQKDLNILTDPEYKNGFNTLVSHQNVSNLSSCGLCLSE 1405
+S + +D+ DS++ + D K + +D + K+ + S + N S S
Sbjct: 604 SSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSS 663
Query: 1406 KEAELDKKHSSLD-----DFENCSLRKFQDENAYTSFDMEEPRTSEEPGSITNSMTSSER 1460
++ S D D N S +++ +S + +S+ S +S SS
Sbjct: 664 NSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSS--DSSDSSNS 721
Query: 1461 NISELESFEELENHDTDIFNTVVNGGEQATEELIQEEVEASKTLELIDISSKNIMEEKRM 1520
N S+ +S ++ D+ + + + + + ++S + + D S + +
Sbjct: 722 NSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN 781
Query: 1521 NGIIYEIISKRLATPPSLDFCYDSKQNSEKETNEGETKMVKMMVKTMETGSYSESSPDLK 1580
+ + + ++ DS +S+ + + S S +S D
Sbjct: 782 SSDSNDSSNSSDSS--------DSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSS 833
Query: 1581 KCIKSPVTSDWSDYRPDSDSEQPYKTSSDDPNDSGELTQEKEYNIGFVKRAIEKLYGKAD 1640
S +SD SD SDS+ ++ S + +DS + + + + +D
Sbjct: 834 DSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSD 893
Query: 1641 IIKPSFFPGSTRKSQVCPYNSVEFQCSRKASLYDSEGQSFGSSEQVSSSSSMLQEFQEER 1700
S S+ NS + S +S S +S SS+S +
Sbjct: 894 SSDSS---NSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDS 950
Query: 1701 QDKCDVSAVRDNYCRGDIVEPGTKQNDDSRILTD 1734
+ D S D+ D + + + DS +D
Sbjct: 951 SNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSD 984
Score = 38.1 bits (87), Expect = 0.094
Identities = 71/428 (16%), Positives = 159/428 (37%), Gaps = 14/428 (3%)
Query: 1189 STTSHFGLSEKEQDMVPIDLSANCSTVNIQSVPKCSENERTQGISSLDGGCSASEACAPE 1248
S +S S D + S+N S + S S+++ + +S D S++ + + E
Sbjct: 868 SDSSDSSNSSDSSDSSDSNESSNSSDSSDSS--NSSDSDSSDSSNSSDSSDSSNSSDSSE 925
Query: 1249 VCVLEVTCSPCEMCTVNKAYSPKETCNPSDTFFPSDGYGVDQTSMNKACFLGEVCSLTDT 1308
+ + + + ++ N SD+ SD +S + + + + +D+
Sbjct: 926 SSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDS 985
Query: 1309 VFSDKACAQKENHTYEGACPIDETYVPVNVCNTIDFLNSKENTYT-DNLDSTEELERGDD 1367
S + ++ + ++ + N+ D NS +++ + D+ DS++ + D
Sbjct: 986 SDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDS 1045
Query: 1368 IQKDLNILTDPEYKNGFNTLVSHQNVSNLSSCGLCLSEKEAELDKKHSSLDDFENCSLRK 1427
+ + + ++ S + S+ SS SE D +SS + S
Sbjct: 1046 SDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDS 1105
Query: 1428 FQDENAYTSFDMEEPRTSEEPGSITNSMTSSERNISELESFEELENHDTDIFNTVVNGGE 1487
++ S D + S + ++S SS+ + S +S + E+ D+ + + +
Sbjct: 1106 SDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSS-DSSDSSESSDSSDSSDSSDSSD 1164
Query: 1488 QATEELIQEEVEASKTLELIDISSKNIMEEKRMNGIIYEIISKRLATPPSLDFCYDSKQN 1547
+ + ++S + + D S + + S + S D S +
Sbjct: 1165 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSDS----------SDSSDSSDSSDSSDSSDSS 1214
Query: 1548 SEKETNEGETKMVKMMVKTMETGSYSESSPDLKKCIKSPVTSDWSDYRPDSDSEQPYKTS 1607
++++ S S S D S +SD SD DS+ E ++
Sbjct: 1215 DSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSK 1274
Query: 1608 SDDPNDSG 1615
S + N++G
Sbjct: 1275 SGNGNNNG 1282
Score = 34.3 bits (77), Expect = 1.4
Identities = 67/383 (17%), Positives = 137/383 (35%), Gaps = 31/383 (8%)
Query: 255 NAKSESRKISTHMSSSSRSQIYSVSSEKTHNNDCYLDYSFVPEKYLALEKNDSQNLPIYP 314
N+ S S++ S SS S S SS + +++ D S + + E +DS +
Sbjct: 653 NSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSS-DSSDSSDSSNSSESSDSSDSSDSD 711
Query: 315 SEDDIEKSIIFNQDGTMTVEMKVRFRIKEEETIKWTTTVSKTGPSNNDEKSEMSFPGRTE 374
S D + S + D + + + SN+ + S+ S +
Sbjct: 712 SSDSSDSSNSNSSDSDSS------------------NSSDSSDSSNSSDSSDSSDSSNSS 753
Query: 375 SRSSGLKLAACSFSADVSPMERSSNQEGSLAEEINIQMTDQVAETCSSASWENATVDTDI 434
S + S S+D S SS+ S + +D +++ +S+ N++ +D
Sbjct: 754 DSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDS-SDSSNSSDSSNSSDSSDS 812
Query: 435 IQGTQDQAKHRFYRPPTPGLRRVRQKKSVIGSVTLVSETEVQEKMIGQFSYSEERESGEN 494
+ + + S ++ + G S S R N
Sbjct: 813 SDSSDSDSSNS---------SDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSN 863
Query: 495 KSEYHMFTHSCSKMSSVSNKPVLVQINNNDQMEESSLERKKENSLLKSSAISAGVIEITS 554
S+ + S + S + N++D + S+ + SS S S
Sbjct: 864 SSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDS 923
Query: 555 QKMLEMSHNNGLPSTISNNSIVEEDVVDCVVLDNKTGIKNFKTYGNTNDRFSPISADATH 614
+ S N+ S+ S+NS D D + + + +++D S S+D+++
Sbjct: 924 SESSNSSDNSN--SSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSN 981
Query: 615 FSSNNSGTDKNISEAPASEASST 637
S ++ +D + S + ++S+
Sbjct: 982 SSDSSDSSDSSDSSDSSDSSNSS 1004
Score = 32.3 bits (72), Expect = 5.2
Identities = 67/368 (18%), Positives = 126/368 (34%), Gaps = 9/368 (2%)
Query: 1346 NSKENTYTDNLDSTEELERGDDIQKDLNILTDPEYKNGFNTLVSHQNVSNLSSCGLCLSE 1405
NS ++ +++ DS++ D + + + ++ S + S+ SS S
Sbjct: 722 NSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN 781
Query: 1406 KEAELDKKHSSLDDFENCSLRKFQDENAYTSFDMEEPRTSEEPGSITNSMTSSERNISEL 1465
D +SS + S ++ S D + +S S +S +S N S+
Sbjct: 782 SSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDS 841
Query: 1466 -ESFEELENHDTDIFNTVVNGGEQATEELIQEEVEASKTLELIDISSKNIMEEKRMNGII 1524
+S + + D+D N + + + ++S + + D S N E +
Sbjct: 842 SDSSDSSDGSDSDSSNR----SDSSNSSDSSDSSDSSNSSDSSDSSDSN--ESSNSSDSS 895
Query: 1525 YEIISKRLATPPSLDFCYDSKQNSEKETNEGETKMVKMMVKTMETGSYSESSPDLKKCIK 1584
S + S + S ++ +++E S S S D
Sbjct: 896 DSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSD 955
Query: 1585 SPVTSDWSDYRPDSDSEQPYKTSSDDPNDSGELTQEKEYNIGFVKRAIEKLYGKADIIKP 1644
S +SD S+ SDS + S + +DS + + + + +D
Sbjct: 956 SSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1015
Query: 1645 SFFPGSTRKSQVCPYNSVEFQCSRKASLYDSEGQSFGSSEQVSSSSSMLQEFQEERQDKC 1704
S S+ S NS + S +S S SS+ +SS S + D
Sbjct: 1016 SNSSDSSNSSD--SSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 1073
Query: 1705 DVSAVRDN 1712
D S D+
Sbjct: 1074 DSSDSSDS 1081
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 38.5 bits (88), Expect = 0.072
Identities = 48/255 (18%), Positives = 105/255 (41%), Gaps = 22/255 (8%)
Query: 1330 DETYVPVNVCNTIDFLNSKENTYTDNLDSTEELERGDDIQKDLNILTDPEYKNGFNTLVS 1389
+ET +NV + L + N+ D LD EE+E ++++ ++ L S
Sbjct: 1326 EETRQKLNVSTKLRQLEEERNSLQDQLD--EEMEAKQNLERHISTL-------NIQLSDS 1376
Query: 1390 HQNVSNLSSCGLCLSEKEAELDKKHSSLDDFENCSLRKFQDENAYTSFDMEEPRTSEEPG 1449
+ + + +S L E + K + EN + + + AY + + R +E
Sbjct: 1377 KKKLQDFASTVEALEEGKKRFQK------EIENLTQQYEEKAAAYDKLEKTKNRLQQELD 1430
Query: 1450 SITNSMTSSERNISELE----SFEELENHDTDIFNTVVNGGEQATEELIQEEVEASKTLE 1505
+ + + + +S LE F++L + +I + + ++A E ++E +A
Sbjct: 1431 DLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLAR 1490
Query: 1506 LIDISSKNIMEEKRMNGIIYEIISKRLATPPSLDFCYDSKQNSEKETNEGETKMVKMMVK 1565
++ + + E +R N ++ + ++ S D + EK ET+M +M +
Sbjct: 1491 ALEEALEAKEELERTNKMLKAEMEDLVS---SKDDVGKNVHELEKSKRALETQMEEMKTQ 1547
Query: 1566 TMETGSYSESSPDLK 1580
E +++ D K
Sbjct: 1548 LEELEDELQATEDAK 1562
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 38.5 bits (88), Expect = 0.072
Identities = 48/255 (18%), Positives = 105/255 (41%), Gaps = 22/255 (8%)
Query: 1330 DETYVPVNVCNTIDFLNSKENTYTDNLDSTEELERGDDIQKDLNILTDPEYKNGFNTLVS 1389
+ET +NV + L + N+ D LD EE+E ++++ ++ L S
Sbjct: 1333 EETRQKLNVSTKLRQLEEERNSLQDQLD--EEMEAKQNLERHISTL-------NIQLSDS 1383
Query: 1390 HQNVSNLSSCGLCLSEKEAELDKKHSSLDDFENCSLRKFQDENAYTSFDMEEPRTSEEPG 1449
+ + + +S L E + K + EN + + + AY + + R +E
Sbjct: 1384 KKKLQDFASTVEALEEGKKRFQK------EIENLTQQYEEKAAAYDKLEKTKNRLQQELD 1437
Query: 1450 SITNSMTSSERNISELE----SFEELENHDTDIFNTVVNGGEQATEELIQEEVEASKTLE 1505
+ + + + +S LE F++L + +I + + ++A E ++E +A
Sbjct: 1438 DLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLAR 1497
Query: 1506 LIDISSKNIMEEKRMNGIIYEIISKRLATPPSLDFCYDSKQNSEKETNEGETKMVKMMVK 1565
++ + + E +R N ++ + ++ S D + EK ET+M +M +
Sbjct: 1498 ALEEALEAKEELERTNKMLKAEMEDLVS---SKDDVGKNVHELEKSKRALETQMEEMKTQ 1554
Query: 1566 TMETGSYSESSPDLK 1580
E +++ D K
Sbjct: 1555 LEELEDELQATEDAK 1569
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 38.5 bits (88), Expect = 0.072
Identities = 48/255 (18%), Positives = 105/255 (41%), Gaps = 22/255 (8%)
Query: 1330 DETYVPVNVCNTIDFLNSKENTYTDNLDSTEELERGDDIQKDLNILTDPEYKNGFNTLVS 1389
+ET +NV + L + N+ D LD EE+E ++++ ++ L S
Sbjct: 1333 EETRQKLNVSTKLRQLEEERNSLQDQLD--EEMEAKQNLERHISTL-------NIQLSDS 1383
Query: 1390 HQNVSNLSSCGLCLSEKEAELDKKHSSLDDFENCSLRKFQDENAYTSFDMEEPRTSEEPG 1449
+ + + +S L E + K + EN + + + AY + + R +E
Sbjct: 1384 KKKLQDFASTVEALEEGKKRFQK------EIENLTQQYEEKAAAYDKLEKTKNRLQQELD 1437
Query: 1450 SITNSMTSSERNISELE----SFEELENHDTDIFNTVVNGGEQATEELIQEEVEASKTLE 1505
+ + + + +S LE F++L + +I + + ++A E ++E +A
Sbjct: 1438 DLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLAR 1497
Query: 1506 LIDISSKNIMEEKRMNGIIYEIISKRLATPPSLDFCYDSKQNSEKETNEGETKMVKMMVK 1565
++ + + E +R N ++ + ++ S D + EK ET+M +M +
Sbjct: 1498 ALEEALEAKEELERTNKMLKAEMEDLVS---SKDDVGKNVHELEKSKRALETQMEEMKTQ 1554
Query: 1566 TMETGSYSESSPDLK 1580
E +++ D K
Sbjct: 1555 LEELEDELQATEDAK 1569
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 38.5 bits (88), Expect = 0.072
Identities = 48/255 (18%), Positives = 105/255 (41%), Gaps = 22/255 (8%)
Query: 1330 DETYVPVNVCNTIDFLNSKENTYTDNLDSTEELERGDDIQKDLNILTDPEYKNGFNTLVS 1389
+ET +NV + L + N+ D LD EE+E ++++ ++ L S
Sbjct: 1326 EETRQKLNVSTKLRQLEEERNSLQDQLD--EEMEAKQNLERHISTL-------NIQLSDS 1376
Query: 1390 HQNVSNLSSCGLCLSEKEAELDKKHSSLDDFENCSLRKFQDENAYTSFDMEEPRTSEEPG 1449
+ + + +S L E + K + EN + + + AY + + R +E
Sbjct: 1377 KKKLQDFASTVEALEEGKKRFQK------EIENLTQQYEEKAAAYDKLEKTKNRLQQELD 1430
Query: 1450 SITNSMTSSERNISELE----SFEELENHDTDIFNTVVNGGEQATEELIQEEVEASKTLE 1505
+ + + + +S LE F++L + +I + + ++A E ++E +A
Sbjct: 1431 DLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLAR 1490
Query: 1506 LIDISSKNIMEEKRMNGIIYEIISKRLATPPSLDFCYDSKQNSEKETNEGETKMVKMMVK 1565
++ + + E +R N ++ + ++ S D + EK ET+M +M +
Sbjct: 1491 ALEEALEAKEELERTNKMLKAEMEDLVS---SKDDVGKNVHELEKSKRALETQMEEMKTQ 1547
Query: 1566 TMETGSYSESSPDLK 1580
E +++ D K
Sbjct: 1548 LEELEDELQATEDAK 1562
>gi|4759082 serum deprivation response protein [Homo sapiens]
Length = 425
Score = 38.1 bits (87), Expect = 0.094
Identities = 46/180 (25%), Positives = 77/180 (42%), Gaps = 19/180 (10%)
Query: 1460 RNISELESFEELENHDTDIF-NTVVNGGEQATEELIQEEVEASKTLELIDISS------- 1511
RN ++ F+E +F V+G + EEL E +TL +D+SS
Sbjct: 152 RNHFKVLIFQEENEIPASVFVKQPVSGAVEGKEELPDENKSLEETLHTVDLSSDDDLPHD 211
Query: 1512 ----KNIMEEKRMNGIIYEIISKRLATPPSLDFCYDSKQNSEKETNEGETKMVKM----M 1563
++ EEK +I L SL + S+QN EK+ N+ TK+V +
Sbjct: 212 EEALEDSAEEKVEESRAEKIKRSSLKKVDSLKKAF-SRQNIEKKMNKLGTKIVSVERREK 270
Query: 1564 VKTMETGSYSESSPDLKKCIK-SPVTSDWSDYRPDSDSEQPYKTSSDDPNDSGELTQEKE 1622
+K T ++ + S K SP+T R + +S +T S+D S ++ ++E
Sbjct: 271 IKKSLTSNHQKISSGKSSPFKVSPLTFGRKKVR-EGESHAENETKSEDLPSSEQMPNDQE 329
>gi|151301098 zinc finger, DBF-type containing 2 [Homo sapiens]
Length = 2354
Score = 37.4 bits (85), Expect = 0.16
Identities = 173/821 (21%), Positives = 297/821 (36%), Gaps = 133/821 (16%)
Query: 374 ESRSSGLKLAACSFSADVSPMERSSNQEGSLAEEINIQMTDQVAETCSSASWENATVDTD 433
E RS + +F +D P S ++ L E + D E+C S S E T D+D
Sbjct: 739 EVRSYDCSSSELTFDSD--PPLLSVTEQSHLDAEGKERHIDLEDESCESDSSE-ITFDSD 795
Query: 434 I-IQGTQDQAKHRFYRPPTPGLRRVRQKKSVIGSVTLVSETEVQ----------EKMIGQ 482
I + DQ + Y T L + +S + +T S+ + +++I +
Sbjct: 796 IPLYSVIDQPEVAVYEEETVDLES-KSNESCVSEITFDSDIPLHSGNDHPEVAVKEVIQK 854
Query: 483 FSYSEERESGENKSEYHMFTHSCSKMSSVSNKPVLVQINNNDQMEESSLERKKENSLLKS 542
Y + S + + S + + SV+N P + N Q EE KEN + S
Sbjct: 855 EEYIHLERKNDEPSGSEISSDSHAPLHSVTNSPEVAVKKLNPQKEEQVHLENKENEPIDS 914
Query: 543 ------SAISAGVIEITSQKMLEMSHNNGLPSTISNNSIVEEDVVDCVVLDNKTGIKN-- 594
+ I V + + E+S + + N S+ E + V L T
Sbjct: 915 EVSLDYNIIFHSVTGRSEDPIKEISLHTKEHMYLENKSVFETSLDSDVPLQAATHKPEVI 974
Query: 595 FKTYGNTNDRFSPISADATHFSSNNSGTDKNISEAPASEASSTVTARIDR-----LINEF 649
K ++ + +T FS + + D + +E V +I+R L N+
Sbjct: 975 VKETWLQREKHAEFQGRSTEFSGSKTSLDSGVPHYSVTEPQVAVN-KINRKKQYVLENKN 1033
Query: 650 AQCGLTKL------PKNEKKILSSVASKKKKKSRQQAINSRYQDGQL---------ATKG 694
+C +++ P +A K+K + NS+ D ++ A K
Sbjct: 1034 DKCSGSEIILDSNVPPQSMTDQPQLAFLKEKHVNLKDKNSKSGDSKITFDSEQLQEAVKK 1093
Query: 695 ILN-KNERINTKGRITK----------EMIVQD-SDSP---LKGGILCEEDLQKSDTVIE 739
I K E I K +I + ++ VQ +D P +K L E+ + V
Sbjct: 1094 IDQWKEEVIGLKNKINEPSTYKLIHHPDVSVQSVADQPKVAIKHVNLGNENHMYLE-VKN 1152
Query: 740 SNTFCSKSNLNS-------------TISKNFH---RNKLNTTQNSKVQ-------GLLTK 776
S CS+ NL+S TI + H K N S+V +
Sbjct: 1153 SQYSCSEMNLDSGFLGQSIVNRPQITILEQEHIELEGKHNQCCGSEVSFDSDDPLQSVAD 1212
Query: 777 RKSRSLNKISLGAPKKREIGQRDKVFPHNESKYCKSTFENKSLFHVFNILEQKPKDFYAP 836
R ++ +ISL K E+ D+ NE+K + +++ L V E+ K+
Sbjct: 1213 RLRETVKEISLW--KDEEVDTEDR---RNEAKGFEIMYDSDVLQPVAGQPEEVVKEVSLW 1267
Query: 837 QSQAEVASGYLRGMAKKSLVSKVT-DSHITLKSQKKRKGDKVKASAILSKQHATTRANSL 895
+ + L K S++ DSH L+S + K +L ++H
Sbjct: 1268 KEHVD-----LENKIVKPTDSRINFDSHEPLQSVTNKIPGANKEINLLREEHVCLDDKGY 1322
Query: 896 ASLKKPDFPEAIAHHSIQNYIQSWLQNINPYPTLKPIKSAPVCRNE-TSVVNCSNNSFSG 954
P E I ++ NI P IK + E S+ + S+NS+S
Sbjct: 1323 V----PSDSEII-----------YVSNI---PLQSVIKQPHILEEEHASLEDKSSNSYSP 1364
Query: 955 NDPHTNSGKISNFVMESNKHITKIAGLTGDNLCKEGDKSFIANDTGEEDLHETQVGSLND 1014
+ ++ E K + +I D++ E DKS+ D V + D
Sbjct: 1365 EESSDSNDSFQAAADELQKPVKEINLWKEDHIYLE-DKSYKLGDFDVSYASHIPVQFVTD 1423
Query: 1015 AYLVPLHE--------------HCTLSQSAINDHNTKSHIAAEKSGPEKKLVYQEINLAR 1060
VP+ E +C + S I H+ H+ +E P+ + Y+E +L +
Sbjct: 1424 QSSVPVKEINLQKKDHNDLENKNCEVCGSEIKCHSC-VHLQSEVDQPQ--VSYKEADLQK 1480
Query: 1061 KRQSV--EAAIQVDPIEEETPKDLLPVLMLHQLQASVPGIH 1099
+ V E Q E D+ ++++Q SV H
Sbjct: 1481 EEHVVMEEKTDQPSDSEMMYDSDVPFQIVVNQFPGSVKETH 1521
>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 37.0 bits (84), Expect = 0.21
Identities = 76/336 (22%), Positives = 122/336 (36%), Gaps = 66/336 (19%)
Query: 1418 DDFENCSLRKFQDENAYTSFDMEEPRTSEEPGSITNSMTSSER----NISELESFEELEN 1473
DD S +K + E T D++E +E N S E+ +EL+S EE +
Sbjct: 1320 DDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPS 1379
Query: 1474 HDTDIFNTVVNGGE-------QATEELI----QEEVEASK-TLELIDISSKNIMEEKRMN 1521
HDT + + + G E EELI +EE+ S+ LE + EE +
Sbjct: 1380 HDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEH 1439
Query: 1522 GIIYEIISKRLATPPSL---------------DFCYDSKQNS-----EKETNEGETKMVK 1561
Y+ + LA +L + C+ S+ NS + ++ +
Sbjct: 1440 EGAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVRSVSS 1499
Query: 1562 MMVKTMETGSYSESSPD----LKKCIKSPVTSDWSDYRPDSDSEQPYKTSSDDPNDSGEL 1617
V +E+G Y++ SP+ +++ TS D SD Q S S E
Sbjct: 1500 PNVPALESG-YTQISPEQGSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIES 1558
Query: 1618 TQEKEYNIGFVKRAIEKLYGKADIIKPSFFPGSTRKSQVCPYNSVEFQC-----SRKASL 1672
T E N PS + ST +C +S + C S +SL
Sbjct: 1559 TTENYEN-------------------PSSY-DSTMGGSICGNSSSQSSCSYGGLSSSSSL 1598
Query: 1673 YDSEGQSFGSSEQVSSSSSMLQEFQEERQDKCDVSA 1708
S + SS SM+Q+ + C + +
Sbjct: 1599 TQSSCVVTQQMASMGSSCSMMQQSSVQPAANCSIKS 1634
>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 37.0 bits (84), Expect = 0.21
Identities = 76/336 (22%), Positives = 122/336 (36%), Gaps = 66/336 (19%)
Query: 1418 DDFENCSLRKFQDENAYTSFDMEEPRTSEEPGSITNSMTSSER----NISELESFEELEN 1473
DD S +K + E T D++E +E N S E+ +EL+S EE +
Sbjct: 1320 DDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPS 1379
Query: 1474 HDTDIFNTVVNGGE-------QATEELI----QEEVEASK-TLELIDISSKNIMEEKRMN 1521
HDT + + + G E EELI +EE+ S+ LE + EE +
Sbjct: 1380 HDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEH 1439
Query: 1522 GIIYEIISKRLATPPSL---------------DFCYDSKQNS-----EKETNEGETKMVK 1561
Y+ + LA +L + C+ S+ NS + ++ +
Sbjct: 1440 EGAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVRSVSS 1499
Query: 1562 MMVKTMETGSYSESSPD----LKKCIKSPVTSDWSDYRPDSDSEQPYKTSSDDPNDSGEL 1617
V +E+G Y++ SP+ +++ TS D SD Q S S E
Sbjct: 1500 PNVPALESG-YTQISPEQGSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIES 1558
Query: 1618 TQEKEYNIGFVKRAIEKLYGKADIIKPSFFPGSTRKSQVCPYNSVEFQC-----SRKASL 1672
T E N PS + ST +C +S + C S +SL
Sbjct: 1559 TTENYEN-------------------PSSY-DSTMGGSICGNSSSQSSCSYGGLSSSSSL 1598
Query: 1673 YDSEGQSFGSSEQVSSSSSMLQEFQEERQDKCDVSA 1708
S + SS SM+Q+ + C + +
Sbjct: 1599 TQSSCVVTQQMASMGSSCSMMQQSSVQPAANCSIKS 1634
>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 37.0 bits (84), Expect = 0.21
Identities = 76/336 (22%), Positives = 122/336 (36%), Gaps = 66/336 (19%)
Query: 1418 DDFENCSLRKFQDENAYTSFDMEEPRTSEEPGSITNSMTSSER----NISELESFEELEN 1473
DD S +K + E T D++E +E N S E+ +EL+S EE +
Sbjct: 1320 DDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPS 1379
Query: 1474 HDTDIFNTVVNGGE-------QATEELI----QEEVEASK-TLELIDISSKNIMEEKRMN 1521
HDT + + + G E EELI +EE+ S+ LE + EE +
Sbjct: 1380 HDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEH 1439
Query: 1522 GIIYEIISKRLATPPSL---------------DFCYDSKQNS-----EKETNEGETKMVK 1561
Y+ + LA +L + C+ S+ NS + ++ +
Sbjct: 1440 EGAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVRSVSS 1499
Query: 1562 MMVKTMETGSYSESSPD----LKKCIKSPVTSDWSDYRPDSDSEQPYKTSSDDPNDSGEL 1617
V +E+G Y++ SP+ +++ TS D SD Q S S E
Sbjct: 1500 PNVPALESG-YTQISPEQGSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIES 1558
Query: 1618 TQEKEYNIGFVKRAIEKLYGKADIIKPSFFPGSTRKSQVCPYNSVEFQC-----SRKASL 1672
T E N PS + ST +C +S + C S +SL
Sbjct: 1559 TTENYEN-------------------PSSY-DSTMGGSICGNSSSQSSCSYGGLSSSSSL 1598
Query: 1673 YDSEGQSFGSSEQVSSSSSMLQEFQEERQDKCDVSA 1708
S + SS SM+Q+ + C + +
Sbjct: 1599 TQSSCVVTQQMASMGSSCSMMQQSSVQPAANCSIKS 1634
>gi|47717112 zinc finger, FYVE domain containing 9 isoform 1 [Homo
sapiens]
Length = 1366
Score = 36.6 bits (83), Expect = 0.27
Identities = 43/173 (24%), Positives = 72/173 (41%), Gaps = 26/173 (15%)
Query: 1330 DETYVPVNVCNTIDFLNSKENTYTDNLDSTE----ELERGDDIQKDLNILTDPEYKNGFN 1385
+E Y T +FLN E+ ++++ D T +L +D Q + E K F
Sbjct: 372 NEGYEHEETLGTTEFLNMTEH-FSESQDMTNWKLTKLNEMNDSQVN-------EEKEKF- 422
Query: 1386 TLVSHQNVSNLSSCGLCLSEKEAELDKKHSSLDDFENCSLRKFQD-------ENAYTSFD 1438
+S +N S G C+ +A LD K + + + E C D N S+
Sbjct: 423 LQISQPEDTNGDSGGQCVGLADAGLDLKGTCISESEECDFSTVIDTPAANYLSNGCDSYG 482
Query: 1439 MEEPRTSEEPGSITNSMTSSERNISELESFEELENHDTDIFNTVVNGGEQATE 1491
M++P S P ++ S E +++E + EE ++ N G +ATE
Sbjct: 483 MQDPGVSFVP----KTLPSKEDSVTEEKEIEESKSECYS--NIYEQRGNEATE 529
>gi|47717106 zinc finger, FYVE domain containing 9 isoform 3 [Homo
sapiens]
Length = 1425
Score = 36.6 bits (83), Expect = 0.27
Identities = 43/173 (24%), Positives = 72/173 (41%), Gaps = 26/173 (15%)
Query: 1330 DETYVPVNVCNTIDFLNSKENTYTDNLDSTE----ELERGDDIQKDLNILTDPEYKNGFN 1385
+E Y T +FLN E+ ++++ D T +L +D Q + E K F
Sbjct: 372 NEGYEHEETLGTTEFLNMTEH-FSESQDMTNWKLTKLNEMNDSQVN-------EEKEKF- 422
Query: 1386 TLVSHQNVSNLSSCGLCLSEKEAELDKKHSSLDDFENCSLRKFQD-------ENAYTSFD 1438
+S +N S G C+ +A LD K + + + E C D N S+
Sbjct: 423 LQISQPEDTNGDSGGQCVGLADAGLDLKGTCISESEECDFSTVIDTPAANYLSNGCDSYG 482
Query: 1439 MEEPRTSEEPGSITNSMTSSERNISELESFEELENHDTDIFNTVVNGGEQATE 1491
M++P S P ++ S E +++E + EE ++ N G +ATE
Sbjct: 483 MQDPGVSFVP----KTLPSKEDSVTEEKEIEESKSECYS--NIYEQRGNEATE 529
>gi|6552337 zinc finger, FYVE domain containing 9 isoform 2 [Homo
sapiens]
Length = 762
Score = 36.6 bits (83), Expect = 0.27
Identities = 43/173 (24%), Positives = 72/173 (41%), Gaps = 26/173 (15%)
Query: 1330 DETYVPVNVCNTIDFLNSKENTYTDNLDSTE----ELERGDDIQKDLNILTDPEYKNGFN 1385
+E Y T +FLN E+ ++++ D T +L +D Q + E K F
Sbjct: 372 NEGYEHEETLGTTEFLNMTEH-FSESQDMTNWKLTKLNEMNDSQVN-------EEKEKF- 422
Query: 1386 TLVSHQNVSNLSSCGLCLSEKEAELDKKHSSLDDFENCSLRKFQD-------ENAYTSFD 1438
+S +N S G C+ +A LD K + + + E C D N S+
Sbjct: 423 LQISQPEDTNGDSGGQCVGLADAGLDLKGTCISESEECDFSTVIDTPAANYLSNGCDSYG 482
Query: 1439 MEEPRTSEEPGSITNSMTSSERNISELESFEELENHDTDIFNTVVNGGEQATE 1491
M++P S P ++ S E +++E + EE ++ N G +ATE
Sbjct: 483 MQDPGVSFVP----KTLPSKEDSVTEEKEIEESKSECYS--NIYEQRGNEATE 529
>gi|239747116 PREDICTED: hypothetical protein XP_002343915 isoform 2
[Homo sapiens]
Length = 551
Score = 35.8 bits (81), Expect = 0.47
Identities = 47/220 (21%), Positives = 80/220 (36%), Gaps = 20/220 (9%)
Query: 359 SNNDEKSEMSFPGRTESRSSGLKLAACSFSADVSPMERSSNQEGSLAEEINIQMTDQVAE 418
S+ EK + + LKL + S + E S ++ S EIN +V E
Sbjct: 325 SDYKEKQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPEINKDCDREVEE 384
Query: 419 TCSSASWENATVDTDIIQGTQDQAKHRFYRPPTPGLRRVRQKKSVIGSVTLVSETEVQEK 478
+ ++ G P RR R+ ++ T E E+
Sbjct: 385 EIKKHGSNPVGLPENLTNGASAGNGDDGLIPQ----RRSRKPENQQFPDTENEEYHSDEQ 440
Query: 479 MIGQFSYSEERESGENKSEYHMFTHSCSKMSSVSNKPVLVQINNNDQMEESSLERKKENS 538
+ SEE+ +G ++ E ++NK +++ E SL KKE
Sbjct: 441 NDTRKQLSEEQNTGISQDEI------------LTNKQKQIEVAEQKMNSELSLSHKKEED 488
Query: 539 LLKSSAISAGVIEITSQKMLEMSHNNGLPSTISNNSIVEE 578
LL+ +++ I + ++ E H N L N I+EE
Sbjct: 489 LLRENSVLQEEIAVLRLELDETKHQNQL----RENKILEE 524
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.128 0.363
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 82,822,396
Number of Sequences: 37866
Number of extensions: 3867487
Number of successful extensions: 10358
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 75
Number of HSP's that attempted gapping in prelim test: 10091
Number of HSP's gapped (non-prelim): 281
length of query: 2156
length of database: 18,247,518
effective HSP length: 118
effective length of query: 2038
effective length of database: 13,779,330
effective search space: 28082274540
effective search space used: 28082274540
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.