Search of human proteins with 5453950

Search of human proteins with 5453950

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5453950 protein phosphatase 2, regulatory subunit B (B56),
alpha isoform [Homo sapiens]
         (486 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5453950 protein phosphatase 2, regulatory subunit B (B56), al...   960   0.0  
gi|5453956 epsilon isoform of regulatory subunit B56, protein ph...   749   0.0  
gi|5453952 beta isoform of regulatory subunit B56, protein phosp...   701   0.0  
gi|240849359 gamma isoform of regulatory subunit B56, protein ph...   624   e-179
gi|5453954 delta isoform of regulatory subunit B56, protein phos...   621   e-178
gi|240849353 gamma isoform of regulatory subunit B56, protein ph...   615   e-176
gi|31083259 gamma isoform of regulatory subunit B56, protein pho...   612   e-175
gi|31083243 gamma isoform of regulatory subunit B56, protein pho...   609   e-174
gi|31083236 gamma isoform of regulatory subunit B56, protein pho...   609   e-174
gi|31083280 delta isoform of regulatory subunit B56, protein pho...   606   e-173
gi|31083288 delta isoform of regulatory subunit B56, protein pho...   601   e-172
gi|224458301 family with sequence similarity 186, member A [Homo...    39   0.011
gi|31542634 filamin A interacting protein 1 [Homo sapiens]             35   0.12 
gi|32967605 bromodomain adjacent to zinc finger domain, 1A isofo...    35   0.15 
gi|32967603 bromodomain adjacent to zinc finger domain, 1A isofo...    35   0.15 
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]         34   0.26 
gi|194294523 intersectin 2 isoform 3 [Homo sapiens]                    34   0.34 
gi|194294521 intersectin 2 isoform 1 [Homo sapiens]                    34   0.34 
gi|194294525 intersectin 2 isoform 2 [Homo sapiens]                    34   0.34 
gi|5031825 ring finger protein 103 [Homo sapiens]                      33   0.58 
gi|112734867 retinitis pigmentosa GTPase regulator interacting p...    33   0.76 
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]                32   0.99 
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]                32   0.99 
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ...    32   1.7  
gi|87116683 proline/serine-rich coiled-coil 2 [Homo sapiens]           31   2.2  
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa...    31   2.9  
gi|33286444 mastermind-like 2 [Homo sapiens]                           31   2.9  
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik...    31   2.9  
gi|115648142 centrosomal protein 164kDa [Homo sapiens]                 31   2.9  
gi|209862748 ataxin 3-like [Homo sapiens]                              31   2.9  

>gi|5453950 protein phosphatase 2, regulatory subunit B (B56), alpha
           isoform [Homo sapiens]
          Length = 486

 Score =  960 bits (2482), Expect = 0.0
 Identities = 486/486 (100%), Positives = 486/486 (100%)

Query: 1   MSSSSPPAGAASAAISASEKVDGFTRKSVRKAQRQKRSQGSSQFRSQGSQAELHPLPQLK 60
           MSSSSPPAGAASAAISASEKVDGFTRKSVRKAQRQKRSQGSSQFRSQGSQAELHPLPQLK
Sbjct: 1   MSSSSPPAGAASAAISASEKVDGFTRKSVRKAQRQKRSQGSSQFRSQGSQAELHPLPQLK 60

Query: 61  DATSNEQQELFCQKLQQCCILFDFMDSVSDLKSKEIKRATLNELVEYVSTNRGVIVESAY 120
           DATSNEQQELFCQKLQQCCILFDFMDSVSDLKSKEIKRATLNELVEYVSTNRGVIVESAY
Sbjct: 61  DATSNEQQELFCQKLQQCCILFDFMDSVSDLKSKEIKRATLNELVEYVSTNRGVIVESAY 120

Query: 121 SDIVKMISANIFRTLPPSDNPDFDPEEDEPTLEASWPHIQLVYEFFLRFLESPDFQPSIA 180
           SDIVKMISANIFRTLPPSDNPDFDPEEDEPTLEASWPHIQLVYEFFLRFLESPDFQPSIA
Sbjct: 121 SDIVKMISANIFRTLPPSDNPDFDPEEDEPTLEASWPHIQLVYEFFLRFLESPDFQPSIA 180

Query: 181 KRYIDQKFVQQLLELFDSEDPRERDFLKTVLHRIYGKFLGLRAFIRKQINNIFLRFIYET 240
           KRYIDQKFVQQLLELFDSEDPRERDFLKTVLHRIYGKFLGLRAFIRKQINNIFLRFIYET
Sbjct: 181 KRYIDQKFVQQLLELFDSEDPRERDFLKTVLHRIYGKFLGLRAFIRKQINNIFLRFIYET 240

Query: 241 EHFNGVAELLEILGSIINGFALPLKAEHKQFLMKVLIPMHTAKGLALFHAQLAYCVVQFL 300
           EHFNGVAELLEILGSIINGFALPLKAEHKQFLMKVLIPMHTAKGLALFHAQLAYCVVQFL
Sbjct: 241 EHFNGVAELLEILGSIINGFALPLKAEHKQFLMKVLIPMHTAKGLALFHAQLAYCVVQFL 300

Query: 301 EKDTTLTEPVIRGLLKFWPKTCSQKEVMFLGEIEEILDVIEPTQFKKIEEPLFKQISKCV 360
           EKDTTLTEPVIRGLLKFWPKTCSQKEVMFLGEIEEILDVIEPTQFKKIEEPLFKQISKCV
Sbjct: 301 EKDTTLTEPVIRGLLKFWPKTCSQKEVMFLGEIEEILDVIEPTQFKKIEEPLFKQISKCV 360

Query: 361 SSSHFQVAERALYFWNNEYILSLIEENIDKILPIMFASLYKISKEHWNPTIVALVYNVLK 420
           SSSHFQVAERALYFWNNEYILSLIEENIDKILPIMFASLYKISKEHWNPTIVALVYNVLK
Sbjct: 361 SSSHFQVAERALYFWNNEYILSLIEENIDKILPIMFASLYKISKEHWNPTIVALVYNVLK 420

Query: 421 TLMEMNGKLFDDLTSSYKAERQREKKKELEREELWKKLEELKLKKALEKQNSAYNMHSIL 480
           TLMEMNGKLFDDLTSSYKAERQREKKKELEREELWKKLEELKLKKALEKQNSAYNMHSIL
Sbjct: 421 TLMEMNGKLFDDLTSSYKAERQREKKKELEREELWKKLEELKLKKALEKQNSAYNMHSIL 480

Query: 481 SNTSAE 486
           SNTSAE
Sbjct: 481 SNTSAE 486


>gi|5453956 epsilon isoform of regulatory subunit B56, protein
           phosphatase 2A [Homo sapiens]
          Length = 467

 Score =  749 bits (1933), Expect = 0.0
 Identities = 361/451 (80%), Positives = 413/451 (91%), Gaps = 1/451 (0%)

Query: 19  EKVDGFTRKSVRKAQRQKRSQGSSQFRSQGSQAELHPLPQLKDATSNEQQELFCQKLQQC 78
           +KVDGF+RKSVRKA RQKRSQ SSQFRSQG   EL PLP LKD  S+EQ ELF +KLQQC
Sbjct: 12  DKVDGFSRKSVRKA-RQKRSQSSSQFRSQGKPIELTPLPLLKDVPSSEQPELFLKKLQQC 70

Query: 79  CILFDFMDSVSDLKSKEIKRATLNELVEYVSTNRGVIVESAYSDIVKMISANIFRTLPPS 138
           C++FDFMD++SDLK KE KR+TLNELV+Y++ +RG + E  Y ++V+M+S NIFRTLPPS
Sbjct: 71  CVIFDFMDTLSDLKMKEYKRSTLNELVDYITISRGCLTEQTYPEVVRMVSCNIFRTLPPS 130

Query: 139 DNPDFDPEEDEPTLEASWPHIQLVYEFFLRFLESPDFQPSIAKRYIDQKFVQQLLELFDS 198
           D+ +FDPEEDEPTLEASWPH+QLVYEFF+RFLES +FQPSIAK+YIDQKFV QLLELFDS
Sbjct: 131 DSNEFDPEEDEPTLEASWPHLQLVYEFFIRFLESQEFQPSIAKKYIDQKFVLQLLELFDS 190

Query: 199 EDPRERDFLKTVLHRIYGKFLGLRAFIRKQINNIFLRFIYETEHFNGVAELLEILGSIIN 258
           EDPRERD+LKTVLHRIYGKFLGLRAFIRKQINNIFLRF+YETEHFNGVAELLEILGSIIN
Sbjct: 191 EDPRERDYLKTVLHRIYGKFLGLRAFIRKQINNIFLRFVYETEHFNGVAELLEILGSIIN 250

Query: 259 GFALPLKAEHKQFLMKVLIPMHTAKGLALFHAQLAYCVVQFLEKDTTLTEPVIRGLLKFW 318
           GFALPLKAEHKQFL+KVLIP+HT + L+LFHAQLAYC+VQFLEKD +LTEPVIRGL+KFW
Sbjct: 251 GFALPLKAEHKQFLVKVLIPLHTVRSLSLFHAQLAYCIVQFLEKDPSLTEPVIRGLMKFW 310

Query: 319 PKTCSQKEVMFLGEIEEILDVIEPTQFKKIEEPLFKQISKCVSSSHFQVAERALYFWNNE 378
           PKTCSQKEVMFLGE+EEILDVIEP+QF KI+EPLFKQI+KCVSS HFQVAERALY+WNNE
Sbjct: 311 PKTCSQKEVMFLGELEEILDVIEPSQFVKIQEPLFKQIAKCVSSPHFQVAERALYYWNNE 370

Query: 379 YILSLIEENIDKILPIMFASLYKISKEHWNPTIVALVYNVLKTLMEMNGKLFDDLTSSYK 438
           YI+SLIEEN + ILPIMF+SLY+ISKEHWNP IVALVYNVLK  MEMN  +FD+LT++YK
Sbjct: 371 YIMSLIEENSNVILPIMFSSLYRISKEHWNPAIVALVYNVLKAFMEMNSTMFDELTATYK 430

Query: 439 AERQREKKKELEREELWKKLEELKLKKALEK 469
           ++RQREKKKE EREELWKKLE+L+LK+ L +
Sbjct: 431 SDRQREKKKEKEREELWKKLEDLELKRGLRR 461


>gi|5453952 beta isoform of regulatory subunit B56, protein
           phosphatase 2A [Homo sapiens]
          Length = 497

 Score =  701 bits (1810), Expect = 0.0
 Identities = 334/464 (71%), Positives = 403/464 (86%), Gaps = 1/464 (0%)

Query: 2   SSSSPPAGAASAAISASEKVDGFTRKSVRKAQRQKRSQGSSQFRSQGSQAELHPLPQLKD 61
           S+ + P+    + +   +KVDGF+R+S+R+A R +RS  SSQFR Q +Q EL PLP LKD
Sbjct: 9   STPTSPSSPGLSPVPPPDKVDGFSRRSLRRA-RPRRSHSSSQFRYQSNQQELTPLPLLKD 67

Query: 62  ATSNEQQELFCQKLQQCCILFDFMDSVSDLKSKEIKRATLNELVEYVSTNRGVIVESAYS 121
             ++E  EL  +KL QC ++FDF+D V+DLK KE+KRA LNELVE V + RGV++E  Y 
Sbjct: 68  VPASELHELLSRKLAQCGVMFDFLDCVADLKGKEVKRAALNELVECVGSTRGVLIEPVYP 127

Query: 122 DIVKMISANIFRTLPPSDNPDFDPEEDEPTLEASWPHIQLVYEFFLRFLESPDFQPSIAK 181
           DI++MIS NIFRTLPPS+NP+FDPEEDEP LE SWPH+QLVYEFFLRFLESPDFQPS+AK
Sbjct: 128 DIIRMISVNIFRTLPPSENPEFDPEEDEPNLEPSWPHLQLVYEFFLRFLESPDFQPSVAK 187

Query: 182 RYIDQKFVQQLLELFDSEDPRERDFLKTVLHRIYGKFLGLRAFIRKQINNIFLRFIYETE 241
           RY+DQKFV  LLELFDSEDPRER++LKT+LHR+YGKFLGLRA+IRKQ N+IFLRFIYE E
Sbjct: 188 RYVDQKFVLMLLELFDSEDPREREYLKTILHRVYGKFLGLRAYIRKQCNHIFLRFIYEFE 247

Query: 242 HFNGVAELLEILGSIINGFALPLKAEHKQFLMKVLIPMHTAKGLALFHAQLAYCVVQFLE 301
           HFNGVAELLEILGSIINGFALPLK EHKQFL++VLIP+H+ K L++FHAQLAYCVVQFLE
Sbjct: 248 HFNGVAELLEILGSIINGFALPLKTEHKQFLVRVLIPLHSVKSLSVFHAQLAYCVVQFLE 307

Query: 302 KDTTLTEPVIRGLLKFWPKTCSQKEVMFLGEIEEILDVIEPTQFKKIEEPLFKQISKCVS 361
           KD TLTE VIRGLLK+WPKTC+QKEVMFLGE+EEILDVIEP+QF KI+EPLFKQ+++CVS
Sbjct: 308 KDATLTEHVIRGLLKYWPKTCTQKEVMFLGEMEEILDVIEPSQFVKIQEPLFKQVARCVS 367

Query: 362 SSHFQVAERALYFWNNEYILSLIEENIDKILPIMFASLYKISKEHWNPTIVALVYNVLKT 421
           S HFQVAERALYFWNNEYILSLIE+N   +LP +F +LY++SKEHWN TIV+L+YNVLKT
Sbjct: 368 SPHFQVAERALYFWNNEYILSLIEDNCHTVLPAVFGTLYQVSKEHWNQTIVSLIYNVLKT 427

Query: 422 LMEMNGKLFDDLTSSYKAERQREKKKELEREELWKKLEELKLKK 465
            MEMNGKLFD+LT+SYK E+Q+E++K  ER+ELW+ LEEL+L++
Sbjct: 428 FMEMNGKLFDELTASYKLEKQQEQQKAQERQELWQGLEELRLRR 471


>gi|240849359 gamma isoform of regulatory subunit B56, protein
           phosphatase 2A isoform f [Homo sapiens]
          Length = 540

 Score =  624 bits (1610), Expect = e-179
 Identities = 314/456 (68%), Positives = 369/456 (80%), Gaps = 10/456 (2%)

Query: 10  AASAAISASEKVDGFTRKSVRKAQRQKRSQGSSQFRSQGSQAELHPLPQLKDATSNEQQE 69
           A  + +SA  KV   ++  V+K +RQ     SS+F S  +  EL  LP LKD    +Q++
Sbjct: 42  AVPSTVSAKIKVP-VSQPIVKKDKRQN----SSRF-SASNNRELQKLPSLKDVPPADQEK 95

Query: 70  LFCQKLQQCCILFDFM-DSVSDLKSKEIKRATLNELVEYVSTNRGVIVESAYSDIVKMIS 128
           LF QKL+QCC+LFDF+ D +SDLK KE+KRA L+E+VEY++ NR VI E  Y ++V M +
Sbjct: 96  LFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFA 155

Query: 129 ANIFRTLPPSDNP---DFDPEEDEPTLEASWPHIQLVYEFFLRFLESPDFQPSIAKRYID 185
            N+FRTLPPS NP   +FDPEEDEPTLEA+WPH+QLVYEFFLRFLESPDFQP+IAK+YID
Sbjct: 156 VNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYID 215

Query: 186 QKFVQQLLELFDSEDPRERDFLKTVLHRIYGKFLGLRAFIRKQINNIFLRFIYETEHFNG 245
           QKFV QLLELFDSEDPRERDFLKT LHRIYGKFLGLRA+IRKQINNIF RFIYETEH NG
Sbjct: 216 QKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNG 275

Query: 246 VAELLEILGSIINGFALPLKAEHKQFLMKVLIPMHTAKGLALFHAQLAYCVVQFLEKDTT 305
           +AELLEILGSIINGFALPLK EHK FL+KVL+P+H  K L+++H QLAYCVVQFLEKD+T
Sbjct: 276 IAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDST 335

Query: 306 LTEPVIRGLLKFWPKTCSQKEVMFLGEIEEILDVIEPTQFKKIEEPLFKQISKCVSSSHF 365
           LTEPV+  LLK+WPKT S KEVMFL E+EEILDVIEP++F KI EPLF+Q++KCVSS HF
Sbjct: 336 LTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHF 395

Query: 366 QVAERALYFWNNEYILSLIEENIDKILPIMFASLYKISKEHWNPTIVALVYNVLKTLMEM 425
           QVAERALY+WNNEYI+SLI +N  KILPIMF SLY+ SK HWN TI  L+YN LK  MEM
Sbjct: 396 QVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEM 455

Query: 426 NGKLFDDLTSSYKAERQREKKKELEREELWKKLEEL 461
           N KLFDD T  +KAE+ +EK K  EREE W K+E L
Sbjct: 456 NQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENL 491


>gi|5453954 delta isoform of regulatory subunit B56, protein
           phosphatase 2A isoform 1 [Homo sapiens]
          Length = 602

 Score =  621 bits (1601), Expect = e-178
 Identities = 299/432 (69%), Positives = 365/432 (84%), Gaps = 5/432 (1%)

Query: 34  RQKRSQGSSQFRSQGSQAELHPLPQLKDATSNEQQELFCQKLQQCCILFDFM-DSVSDLK 92
           +++R Q SS+F    ++ EL  LP LKD+ + E++ELF QKL+QCC+LFDF+ D +SDLK
Sbjct: 82  KKERRQSSSRFNLSKNR-ELQKLPALKDSPTQEREELFIQKLRQCCVLFDFVSDPLSDLK 140

Query: 93  SKEIKRATLNELVEYVSTNRGVIVESAYSDIVKMISANIFRTLPPSDNP---DFDPEEDE 149
            KE+KRA LNE+VEY++ +R V+ E+ Y + V M S N+FRTLPPS NP   +FDPEEDE
Sbjct: 141 FKEVKRAGLNEMVEYITHSRDVVTEAIYPEAVTMFSVNLFRTLPPSSNPTGAEFDPEEDE 200

Query: 150 PTLEASWPHIQLVYEFFLRFLESPDFQPSIAKRYIDQKFVQQLLELFDSEDPRERDFLKT 209
           PTLEA+WPH+QLVYEFFLRFLESPDFQP+IAK+YIDQKFV  LL+LFDSEDPRERDFLKT
Sbjct: 201 PTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLALLDLFDSEDPRERDFLKT 260

Query: 210 VLHRIYGKFLGLRAFIRKQINNIFLRFIYETEHFNGVAELLEILGSIINGFALPLKAEHK 269
           +LHRIYGKFLGLRA+IR+QIN+IF RFIYETEH NG+AELLEILGSIINGFALPLK EHK
Sbjct: 261 ILHRIYGKFLGLRAYIRRQINHIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHK 320

Query: 270 QFLMKVLIPMHTAKGLALFHAQLAYCVVQFLEKDTTLTEPVIRGLLKFWPKTCSQKEVMF 329
            FL++VL+P+H  K L+++H QLAYCVVQFLEK+++LTEPVI GLLKFWPKT S KEVMF
Sbjct: 321 MFLIRVLLPLHKVKSLSVYHPQLAYCVVQFLEKESSLTEPVIVGLLKFWPKTHSPKEVMF 380

Query: 330 LGEIEEILDVIEPTQFKKIEEPLFKQISKCVSSSHFQVAERALYFWNNEYILSLIEENID 389
           L E+EEILDVIEP++F K+ EPLF+Q++KCVSS HFQVAERALY+WNNEYI+SLI +N  
Sbjct: 381 LNELEEILDVIEPSEFSKVMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAA 440

Query: 390 KILPIMFASLYKISKEHWNPTIVALVYNVLKTLMEMNGKLFDDLTSSYKAERQREKKKEL 449
           ++LPIMF +LY+ SK HWN TI  L+YN LK  MEMN KLFDD T  YKAE+Q+ + +  
Sbjct: 441 RVLPIMFPALYRNSKSHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQYKAEKQKGRFRMK 500

Query: 450 EREELWKKLEEL 461
           EREE+W+K+EEL
Sbjct: 501 EREEMWQKIEEL 512


>gi|240849353 gamma isoform of regulatory subunit B56, protein
           phosphatase 2A isoform e [Homo sapiens]
          Length = 555

 Score =  615 bits (1585), Expect = e-176
 Identities = 311/476 (65%), Positives = 368/476 (77%), Gaps = 20/476 (4%)

Query: 23  GFTRKSVRKAQRQKRSQGSSQFRSQGSQAELHPLPQL----------KDATSNEQQELFC 72
           G + KS ++ Q    S+G+S       +     LP+L          +D    +Q++LF 
Sbjct: 15  GKSGKSSKEGQDTVESEGTSPEEPSSPKVPPPLLPELLVLIFGGLQGRDVPPADQEKLFI 74

Query: 73  QKLQQCCILFDFM-DSVSDLKSKEIKRATLNELVEYVSTNRGVIVESAYSDIVKMISANI 131
           QKL+QCC+LFDF+ D +SDLK KE+KRA L+E+VEY++ NR VI E  Y ++V M + N+
Sbjct: 75  QKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNM 134

Query: 132 FRTLPPSDNP---DFDPEEDEPTLEASWPHIQLVYEFFLRFLESPDFQPSIAKRYIDQKF 188
           FRTLPPS NP   +FDPEEDEPTLEA+WPH+QLVYEFFLRFLESPDFQP+IAK+YIDQKF
Sbjct: 135 FRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKF 194

Query: 189 VQQLLELFDSEDPRERDFLKTVLHRIYGKFLGLRAFIRKQINNIFLRFIYETEHFNGVAE 248
           V QLLELFDSEDPRERDFLKT LHRIYGKFLGLRA+IRKQINNIF RFIYETEH NG+AE
Sbjct: 195 VLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAE 254

Query: 249 LLEILGSIINGFALPLKAEHKQFLMKVLIPMHTAKGLALFHAQLAYCVVQFLEKDTTLTE 308
           LLEILGSIINGFALPLK EHK FL+KVL+P+H  K L+++H QLAYCVVQFLEKD+TLTE
Sbjct: 255 LLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTE 314

Query: 309 PVIRGLLKFWPKTCSQKEVMFLGEIEEILDVIEPTQFKKIEEPLFKQISKCVSSSHFQVA 368
           PV+  LLK+WPKT S KEVMFL E+EEILDVIEP++F KI EPLF+Q++KCVSS HFQVA
Sbjct: 315 PVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVA 374

Query: 369 ERALYFWNNEYILSLIEENIDKILPIMFASLYKISKEHWNPTIVALVYNVLKTLMEMNGK 428
           ERALY+WNNEYI+SLI +N  KILPIMF SLY+ SK HWN TI  L+YN LK  MEMN K
Sbjct: 375 ERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQK 434

Query: 429 LFDDLTSSYKAERQREKKKELEREELWKKLEELKLKKALEKQNSAYNMHSILSNTS 484
           LFDD T  +KAE+ +EK K  EREE W K+E       L K N  Y ++S  S  S
Sbjct: 435 LFDDCTQQFKAEKLKEKLKMKEREEAWVKIEN------LAKANPQYTVYSQASTMS 484


>gi|31083259 gamma isoform of regulatory subunit B56, protein
           phosphatase 2A isoform a [Homo sapiens]
          Length = 524

 Score =  612 bits (1577), Expect = e-175
 Identities = 302/433 (69%), Positives = 353/433 (81%), Gaps = 10/433 (2%)

Query: 56  LPQLKDATSNEQQELFCQKLQQCCILFDFM-DSVSDLKSKEIKRATLNELVEYVSTNRGV 114
           L  ++D    +Q++LF QKL+QCC+LFDF+ D +SDLK KE+KRA L+E+VEY++ NR V
Sbjct: 27  LLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNV 86

Query: 115 IVESAYSDIVKMISANIFRTLPPSDNP---DFDPEEDEPTLEASWPHIQLVYEFFLRFLE 171
           I E  Y ++V M + N+FRTLPPS NP   +FDPEEDEPTLEA+WPH+QLVYEFFLRFLE
Sbjct: 87  ITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLE 146

Query: 172 SPDFQPSIAKRYIDQKFVQQLLELFDSEDPRERDFLKTVLHRIYGKFLGLRAFIRKQINN 231
           SPDFQP+IAK+YIDQKFV QLLELFDSEDPRERDFLKT LHRIYGKFLGLRA+IRKQINN
Sbjct: 147 SPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINN 206

Query: 232 IFLRFIYETEHFNGVAELLEILGSIINGFALPLKAEHKQFLMKVLIPMHTAKGLALFHAQ 291
           IF RFIYETEH NG+AELLEILGSIINGFALPLK EHK FL+KVL+P+H  K L+++H Q
Sbjct: 207 IFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQ 266

Query: 292 LAYCVVQFLEKDTTLTEPVIRGLLKFWPKTCSQKEVMFLGEIEEILDVIEPTQFKKIEEP 351
           LAYCVVQFLEKD+TLTEPV+  LLK+WPKT S KEVMFL E+EEILDVIEP++F KI EP
Sbjct: 267 LAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEP 326

Query: 352 LFKQISKCVSSSHFQVAERALYFWNNEYILSLIEENIDKILPIMFASLYKISKEHWNPTI 411
           LF+Q++KCVSS HFQVAERALY+WNNEYI+SLI +N  KILPIMF SLY+ SK HWN TI
Sbjct: 327 LFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTI 386

Query: 412 VALVYNVLKTLMEMNGKLFDDLTSSYKAERQREKKKELEREELWKKLEELKLKKALEKQN 471
             L+YN LK  MEMN KLFDD T  +KAE+ +EK K  EREE W K+E       L K N
Sbjct: 387 HGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIEN------LAKAN 440

Query: 472 SAYNMHSILSNTS 484
             Y ++S  S  S
Sbjct: 441 PQYTVYSQASTMS 453


>gi|31083243 gamma isoform of regulatory subunit B56, protein
           phosphatase 2A isoform c [Homo sapiens]
          Length = 449

 Score =  609 bits (1570), Expect = e-174
 Identities = 296/410 (72%), Positives = 345/410 (84%), Gaps = 4/410 (0%)

Query: 56  LPQLKDATSNEQQELFCQKLQQCCILFDFM-DSVSDLKSKEIKRATLNELVEYVSTNRGV 114
           L  ++D    +Q++LF QKL+QCC+LFDF+ D +SDLK KE+KRA L+E+VEY++ NR V
Sbjct: 27  LLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNV 86

Query: 115 IVESAYSDIVKMISANIFRTLPPSDNP---DFDPEEDEPTLEASWPHIQLVYEFFLRFLE 171
           I E  Y ++V M + N+FRTLPPS NP   +FDPEEDEPTLEA+WPH+QLVYEFFLRFLE
Sbjct: 87  ITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLE 146

Query: 172 SPDFQPSIAKRYIDQKFVQQLLELFDSEDPRERDFLKTVLHRIYGKFLGLRAFIRKQINN 231
           SPDFQP+IAK+YIDQKFV QLLELFDSEDPRERDFLKT LHRIYGKFLGLRA+IRKQINN
Sbjct: 147 SPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINN 206

Query: 232 IFLRFIYETEHFNGVAELLEILGSIINGFALPLKAEHKQFLMKVLIPMHTAKGLALFHAQ 291
           IF RFIYETEH NG+AELLEILGSIINGFALPLK EHK FL+KVL+P+H  K L+++H Q
Sbjct: 207 IFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQ 266

Query: 292 LAYCVVQFLEKDTTLTEPVIRGLLKFWPKTCSQKEVMFLGEIEEILDVIEPTQFKKIEEP 351
           LAYCVVQFLEKD+TLTEPV+  LLK+WPKT S KEVMFL E+EEILDVIEP++F KI EP
Sbjct: 267 LAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEP 326

Query: 352 LFKQISKCVSSSHFQVAERALYFWNNEYILSLIEENIDKILPIMFASLYKISKEHWNPTI 411
           LF+Q++KCVSS HFQVAERALY+WNNEYI+SLI +N  KILPIMF SLY+ SK HWN TI
Sbjct: 327 LFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTI 386

Query: 412 VALVYNVLKTLMEMNGKLFDDLTSSYKAERQREKKKELEREELWKKLEEL 461
             L+YN LK  MEMN KLFDD T  +KAE+ +EK K  EREE W K+E L
Sbjct: 387 HGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENL 436


>gi|31083236 gamma isoform of regulatory subunit B56, protein
           phosphatase 2A isoform b [Homo sapiens]
          Length = 485

 Score =  609 bits (1570), Expect = e-174
 Identities = 296/410 (72%), Positives = 345/410 (84%), Gaps = 4/410 (0%)

Query: 56  LPQLKDATSNEQQELFCQKLQQCCILFDFM-DSVSDLKSKEIKRATLNELVEYVSTNRGV 114
           L  ++D    +Q++LF QKL+QCC+LFDF+ D +SDLK KE+KRA L+E+VEY++ NR V
Sbjct: 27  LLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNV 86

Query: 115 IVESAYSDIVKMISANIFRTLPPSDNP---DFDPEEDEPTLEASWPHIQLVYEFFLRFLE 171
           I E  Y ++V M + N+FRTLPPS NP   +FDPEEDEPTLEA+WPH+QLVYEFFLRFLE
Sbjct: 87  ITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLE 146

Query: 172 SPDFQPSIAKRYIDQKFVQQLLELFDSEDPRERDFLKTVLHRIYGKFLGLRAFIRKQINN 231
           SPDFQP+IAK+YIDQKFV QLLELFDSEDPRERDFLKT LHRIYGKFLGLRA+IRKQINN
Sbjct: 147 SPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINN 206

Query: 232 IFLRFIYETEHFNGVAELLEILGSIINGFALPLKAEHKQFLMKVLIPMHTAKGLALFHAQ 291
           IF RFIYETEH NG+AELLEILGSIINGFALPLK EHK FL+KVL+P+H  K L+++H Q
Sbjct: 207 IFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQ 266

Query: 292 LAYCVVQFLEKDTTLTEPVIRGLLKFWPKTCSQKEVMFLGEIEEILDVIEPTQFKKIEEP 351
           LAYCVVQFLEKD+TLTEPV+  LLK+WPKT S KEVMFL E+EEILDVIEP++F KI EP
Sbjct: 267 LAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEP 326

Query: 352 LFKQISKCVSSSHFQVAERALYFWNNEYILSLIEENIDKILPIMFASLYKISKEHWNPTI 411
           LF+Q++KCVSS HFQVAERALY+WNNEYI+SLI +N  KILPIMF SLY+ SK HWN TI
Sbjct: 327 LFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTI 386

Query: 412 VALVYNVLKTLMEMNGKLFDDLTSSYKAERQREKKKELEREELWKKLEEL 461
             L+YN LK  MEMN KLFDD T  +KAE+ +EK K  EREE W K+E L
Sbjct: 387 HGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENL 436


>gi|31083280 delta isoform of regulatory subunit B56, protein
           phosphatase 2A isoform 2 [Homo sapiens]
          Length = 570

 Score =  606 bits (1562), Expect = e-173
 Identities = 303/471 (64%), Positives = 372/471 (78%), Gaps = 16/471 (3%)

Query: 6   PPAGAASAAISASEKVDGFTRKSVRKAQRQKRSQGSSQFRSQGSQAELHP---------L 56
           PP  A   A  +S   DG   ++  +AQ Q + Q   Q +SQ   +   P         L
Sbjct: 11  PPKVAKCTAKPSSSGKDG-GGENTEEAQPQPQPQPQPQAQSQPPSSNKRPSNSTPPPTQL 69

Query: 57  PQLKDATSNE--QQELFCQKLQQCCILFDFM-DSVSDLKSKEIKRATLNELVEYVSTNRG 113
            ++K +   +  ++ELF QKL+QCC+LFDF+ D +SDLK KE+KRA LNE+VEY++ +R 
Sbjct: 70  SKIKYSGGPQIVKKELFIQKLRQCCVLFDFVSDPLSDLKFKEVKRAGLNEMVEYITHSRD 129

Query: 114 VIVESAYSDIVKMISANIFRTLPPSDNP---DFDPEEDEPTLEASWPHIQLVYEFFLRFL 170
           V+ E+ Y + V M S N+FRTLPPS NP   +FDPEEDEPTLEA+WPH+QLVYEFFLRFL
Sbjct: 130 VVTEAIYPEAVTMFSVNLFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFL 189

Query: 171 ESPDFQPSIAKRYIDQKFVQQLLELFDSEDPRERDFLKTVLHRIYGKFLGLRAFIRKQIN 230
           ESPDFQP+IAK+YIDQKFV  LL+LFDSEDPRERDFLKT+LHRIYGKFLGLRA+IR+QIN
Sbjct: 190 ESPDFQPNIAKKYIDQKFVLALLDLFDSEDPRERDFLKTILHRIYGKFLGLRAYIRRQIN 249

Query: 231 NIFLRFIYETEHFNGVAELLEILGSIINGFALPLKAEHKQFLMKVLIPMHTAKGLALFHA 290
           +IF RFIYETEH NG+AELLEILGSIINGFALPLK EHK FL++VL+P+H  K L+++H 
Sbjct: 250 HIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKMFLIRVLLPLHKVKSLSVYHP 309

Query: 291 QLAYCVVQFLEKDTTLTEPVIRGLLKFWPKTCSQKEVMFLGEIEEILDVIEPTQFKKIEE 350
           QLAYCVVQFLEK+++LTEPVI GLLKFWPKT S KEVMFL E+EEILDVIEP++F K+ E
Sbjct: 310 QLAYCVVQFLEKESSLTEPVIVGLLKFWPKTHSPKEVMFLNELEEILDVIEPSEFSKVME 369

Query: 351 PLFKQISKCVSSSHFQVAERALYFWNNEYILSLIEENIDKILPIMFASLYKISKEHWNPT 410
           PLF+Q++KCVSS HFQVAERALY+WNNEYI+SLI +N  ++LPIMF +LY+ SK HWN T
Sbjct: 370 PLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAARVLPIMFPALYRNSKSHWNKT 429

Query: 411 IVALVYNVLKTLMEMNGKLFDDLTSSYKAERQREKKKELEREELWKKLEEL 461
           I  L+YN LK  MEMN KLFDD T  YKAE+Q+ + +  EREE+W+K+EEL
Sbjct: 430 IHGLIYNALKLFMEMNQKLFDDCTQQYKAEKQKGRFRMKEREEMWQKIEEL 480


>gi|31083288 delta isoform of regulatory subunit B56, protein
           phosphatase 2A isoform 3 [Homo sapiens]
          Length = 496

 Score =  601 bits (1549), Expect = e-172
 Identities = 286/400 (71%), Positives = 345/400 (86%), Gaps = 4/400 (1%)

Query: 66  EQQELFCQKLQQCCILFDFM-DSVSDLKSKEIKRATLNELVEYVSTNRGVIVESAYSDIV 124
           +++ELF QKL+QCC+LFDF+ D +SDLK KE+KRA LNE+VEY++ +R V+ E+ Y + V
Sbjct: 7   KEKELFIQKLRQCCVLFDFVSDPLSDLKFKEVKRAGLNEMVEYITHSRDVVTEAIYPEAV 66

Query: 125 KMISANIFRTLPPSDNP---DFDPEEDEPTLEASWPHIQLVYEFFLRFLESPDFQPSIAK 181
            M S N+FRTLPPS NP   +FDPEEDEPTLEA+WPH+QLVYEFFLRFLESPDFQP+IAK
Sbjct: 67  TMFSVNLFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAK 126

Query: 182 RYIDQKFVQQLLELFDSEDPRERDFLKTVLHRIYGKFLGLRAFIRKQINNIFLRFIYETE 241
           +YIDQKFV  LL+LFDSEDPRERDFLKT+LHRIYGKFLGLRA+IR+QIN+IF RFIYETE
Sbjct: 127 KYIDQKFVLALLDLFDSEDPRERDFLKTILHRIYGKFLGLRAYIRRQINHIFYRFIYETE 186

Query: 242 HFNGVAELLEILGSIINGFALPLKAEHKQFLMKVLIPMHTAKGLALFHAQLAYCVVQFLE 301
           H NG+AELLEILGSIINGFALPLK EHK FL++VL+P+H  K L+++H QLAYCVVQFLE
Sbjct: 187 HHNGIAELLEILGSIINGFALPLKEEHKMFLIRVLLPLHKVKSLSVYHPQLAYCVVQFLE 246

Query: 302 KDTTLTEPVIRGLLKFWPKTCSQKEVMFLGEIEEILDVIEPTQFKKIEEPLFKQISKCVS 361
           K+++LTEPVI GLLKFWPKT S KEVMFL E+EEILDVIEP++F K+ EPLF+Q++KCVS
Sbjct: 247 KESSLTEPVIVGLLKFWPKTHSPKEVMFLNELEEILDVIEPSEFSKVMEPLFRQLAKCVS 306

Query: 362 SSHFQVAERALYFWNNEYILSLIEENIDKILPIMFASLYKISKEHWNPTIVALVYNVLKT 421
           S HFQVAERALY+WNNEYI+SLI +N  ++LPIMF +LY+ SK HWN TI  L+YN LK 
Sbjct: 307 SPHFQVAERALYYWNNEYIMSLISDNAARVLPIMFPALYRNSKSHWNKTIHGLIYNALKL 366

Query: 422 LMEMNGKLFDDLTSSYKAERQREKKKELEREELWKKLEEL 461
            MEMN KLFDD T  YKAE+Q+ + +  EREE+W+K+EEL
Sbjct: 367 FMEMNQKLFDDCTQQYKAEKQKGRFRMKEREEMWQKIEEL 406


>gi|224458301 family with sequence similarity 186, member A [Homo
           sapiens]
          Length = 2351

 Score = 38.9 bits (89), Expect = 0.011
 Identities = 46/197 (23%), Positives = 84/197 (42%), Gaps = 38/197 (19%)

Query: 302 KDTTLTEPVIRGLLKFWPKTCSQKEVMFLGEIEEILDVIEPTQFKKIEEPLFKQISKCVS 361
           KD+T+     + +L   P      E+ F   +++I+  IE  Q  +  E +  Q+S+ ++
Sbjct: 20  KDSTIMRREPQNILS--PLMLPNLEIPF--SVKDIISRIERAQLHRAREDIDMQLSEIMN 75

Query: 362 SSHFQVAERALYF-WNNEYILSLIEEN-------------IDKILPIMFASLYKISK--E 405
           + H  +    L F  ++E  +SL E                 K + I   +L  I    E
Sbjct: 76  NVHRIMTRYTLVFNSSSERNVSLTEHKKKQRTNFLEKMATYAKTIEIREKTLANILAWLE 135

Query: 406 HWNPTI-----------------VALVYNVLKTLMEMNGKLFDDLTSSYKAERQREKKKE 448
            WN  +                 + L+ + LK + E N K+    ++S+  E++++KKK 
Sbjct: 136 EWNDVLSEMTLMDVDEHHHWIAQMELLPDTLKAI-ENNVKILSRFSTSFLDEKKKQKKKI 194

Query: 449 LEREELWKKLEELKLKK 465
           L R  LWK  +E  +K+
Sbjct: 195 LSRGTLWKSWKERVIKR 211


>gi|31542634 filamin A interacting protein 1 [Homo sapiens]
          Length = 1213

 Score = 35.4 bits (80), Expect = 0.12
 Identities = 28/83 (33%), Positives = 44/83 (53%), Gaps = 11/83 (13%)

Query: 401 KISK-EHWNPTIVALVYNVLKTLMEMNGKLFD---------DLTSSYKAERQREKKKELE 450
           KI+K E  N +++A V N+ K ++EM GK  +         +L    + E    K+  LE
Sbjct: 365 KIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLE 424

Query: 451 REELWKKLEEL-KLKKALEKQNS 472
            E+L K++ EL KL++A  K  S
Sbjct: 425 VEKLQKRMSELEKLEEAFSKSKS 447


>gi|32967605 bromodomain adjacent to zinc finger domain, 1A isoform
           b [Homo sapiens]
          Length = 1524

 Score = 35.0 bits (79), Expect = 0.15
 Identities = 19/52 (36%), Positives = 33/52 (63%)

Query: 419 LKTLMEMNGKLFDDLTSSYKAERQREKKKELEREELWKKLEELKLKKALEKQ 470
           +K+L     KL  +   + +A+++ ++ KE +REEL K +EE +LKK  EK+
Sbjct: 317 MKSLAFEKAKLKREKADALEAKKKEKEDKEKKREELKKIVEEERLKKKEEKE 368



 Score = 29.6 bits (65), Expect = 6.4
 Identities = 34/147 (23%), Positives = 68/147 (46%), Gaps = 19/147 (12%)

Query: 338 DVIEPTQFKKIEEPLFKQISKCVSSSHFQVAERALYFWNNEYILSLIE--ENIDKILPIM 395
           D I+P  FK   +P  K++ +       Q++ R   F  ++  L L +  E  D ++ I 
Sbjct: 183 DAIDPLLFKYKVQPTKKELHESAIVKATQISRRKHLFSRDKLKLFLKQHCEPQDGVIKIK 242

Query: 396 FASL--YKISKEHWN-------PTIVALVYNVLKT-------LMEMNGKLFDDLTSSYKA 439
            +SL  YKI+++ ++       PT +    N  +        + + +        +SY++
Sbjct: 243 ASSLSTYKIAEQDFSYFFPDDPPTFIFSPANRRRGRPPKRIHISQEDNVANKQTLASYRS 302

Query: 440 ERQREKKKELEREELWK-KLEELKLKK 465
           +  +E+ K L++EE+     E+ KLK+
Sbjct: 303 KATKERDKLLKQEEMKSLAFEKAKLKR 329


>gi|32967603 bromodomain adjacent to zinc finger domain, 1A isoform
           a [Homo sapiens]
          Length = 1556

 Score = 35.0 bits (79), Expect = 0.15
 Identities = 19/52 (36%), Positives = 33/52 (63%)

Query: 419 LKTLMEMNGKLFDDLTSSYKAERQREKKKELEREELWKKLEELKLKKALEKQ 470
           +K+L     KL  +   + +A+++ ++ KE +REEL K +EE +LKK  EK+
Sbjct: 317 MKSLAFEKAKLKREKADALEAKKKEKEDKEKKREELKKIVEEERLKKKEEKE 368



 Score = 29.6 bits (65), Expect = 6.4
 Identities = 34/147 (23%), Positives = 68/147 (46%), Gaps = 19/147 (12%)

Query: 338 DVIEPTQFKKIEEPLFKQISKCVSSSHFQVAERALYFWNNEYILSLIE--ENIDKILPIM 395
           D I+P  FK   +P  K++ +       Q++ R   F  ++  L L +  E  D ++ I 
Sbjct: 183 DAIDPLLFKYKVQPTKKELHESAIVKATQISRRKHLFSRDKLKLFLKQHCEPQDGVIKIK 242

Query: 396 FASL--YKISKEHWN-------PTIVALVYNVLKT-------LMEMNGKLFDDLTSSYKA 439
            +SL  YKI+++ ++       PT +    N  +        + + +        +SY++
Sbjct: 243 ASSLSTYKIAEQDFSYFFPDDPPTFIFSPANRRRGRPPKRIHISQEDNVANKQTLASYRS 302

Query: 440 ERQREKKKELEREELWK-KLEELKLKK 465
           +  +E+ K L++EE+     E+ KLK+
Sbjct: 303 KATKERDKLLKQEEMKSLAFEKAKLKR 329


>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
          Length = 1317

 Score = 34.3 bits (77), Expect = 0.26
 Identities = 38/157 (24%), Positives = 70/157 (44%), Gaps = 21/157 (13%)

Query: 334  EEILDVIE-PTQFKKIEEPLFKQISKCVSSSHFQVAERALYFWNNEYILSLIEEN----- 387
            E + DV E P  F+KI+   ++           Q  ER L +    ++ +L+EE      
Sbjct: 880  ESVTDVTEVPQDFEKIKPVEYR----------LQYKERQLQYLLQNHLPTLLEEKQRAFE 929

Query: 388  -IDKILPIMFASLYKISKEHWNPTIVALVYNVLKTLMEMNGKLFDDLTSSYKAERQREKK 446
             +D+    +  +LY++ KE          Y      ++     F+  T++   + ++ +K
Sbjct: 930  ILDRGPLSLDNTLYQVEKEMEEKEEQLAQYQANANQLQKLQATFE-FTANIARQEEKVRK 988

Query: 447  KELEREELWKKLEELKLKKAL---EKQNSAYNMHSIL 480
            KE E  E  +K +   L++AL   E+++SA   HS L
Sbjct: 989  KEKEILESREKQQREALERALARLERRHSALQRHSTL 1025


>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
          Length = 1670

 Score = 33.9 bits (76), Expect = 0.34
 Identities = 29/86 (33%), Positives = 43/86 (50%), Gaps = 8/86 (9%)

Query: 385 EENIDKILPIMFASLYKISKEHWNPTIVALVYNVLKTLMEMNGKLFDDLTSSYKAERQRE 444
           EE   K LP+ F    K + E  N  +        + LME   +  +      K E +R 
Sbjct: 352 EEEPQKKLPVTFEDKRKANYERGNMELEKR----RQALMEQQQREAERKAQKEKEEWER- 406

Query: 445 KKKELEREELWKKLEELKLKKALEKQ 470
           K++EL+ +E WKK  +L+L+K LEKQ
Sbjct: 407 KQRELQEQE-WKK--QLELEKRLEKQ 429


>gi|194294521 intersectin 2 isoform 1 [Homo sapiens]
          Length = 1697

 Score = 33.9 bits (76), Expect = 0.34
 Identities = 29/86 (33%), Positives = 43/86 (50%), Gaps = 8/86 (9%)

Query: 385 EENIDKILPIMFASLYKISKEHWNPTIVALVYNVLKTLMEMNGKLFDDLTSSYKAERQRE 444
           EE   K LP+ F    K + E  N  +        + LME   +  +      K E +R 
Sbjct: 352 EEEPQKKLPVTFEDKRKANYERGNMELEKR----RQALMEQQQREAERKAQKEKEEWER- 406

Query: 445 KKKELEREELWKKLEELKLKKALEKQ 470
           K++EL+ +E WKK  +L+L+K LEKQ
Sbjct: 407 KQRELQEQE-WKK--QLELEKRLEKQ 429


>gi|194294525 intersectin 2 isoform 2 [Homo sapiens]
          Length = 1249

 Score = 33.9 bits (76), Expect = 0.34
 Identities = 29/86 (33%), Positives = 43/86 (50%), Gaps = 8/86 (9%)

Query: 385 EENIDKILPIMFASLYKISKEHWNPTIVALVYNVLKTLMEMNGKLFDDLTSSYKAERQRE 444
           EE   K LP+ F    K + E  N  +        + LME   +  +      K E +R 
Sbjct: 352 EEEPQKKLPVTFEDKRKANYERGNMELEKR----RQALMEQQQREAERKAQKEKEEWER- 406

Query: 445 KKKELEREELWKKLEELKLKKALEKQ 470
           K++EL+ +E WKK  +L+L+K LEKQ
Sbjct: 407 KQRELQEQE-WKK--QLELEKRLEKQ 429


>gi|5031825 ring finger protein 103 [Homo sapiens]
          Length = 685

 Score = 33.1 bits (74), Expect = 0.58
 Identities = 19/66 (28%), Positives = 31/66 (46%)

Query: 412 VALVYNVLKTLMEMNGKLFDDLTSSYKAERQREKKKELEREELWKKLEELKLKKALEKQN 471
           VAL +  LKT++E  G  +  L          EK  +L   EL+  L+E +  +++   N
Sbjct: 41  VALSFKKLKTILECRGLGYSGLPEKKDVRELVEKSGDLMEGELYSALKEEEASESVSSTN 100

Query: 472 SAYNMH 477
            +  MH
Sbjct: 101 FSGEMH 106


>gi|112734867 retinitis pigmentosa GTPase regulator interacting
           protein 1 [Homo sapiens]
          Length = 1286

 Score = 32.7 bits (73), Expect = 0.76
 Identities = 24/87 (27%), Positives = 44/87 (50%), Gaps = 8/87 (9%)

Query: 383 LIEENIDKILPIMFASLYKISKEHWNPTIVALVYNVLKTLMEMNGKLFDDLTSSYKAERQ 442
           L+ +N DK+L  M  S    S+ HW+  ++A      + L +   +L D L +  + E +
Sbjct: 373 LLNDNYDKLLESMLDSSDSSSQPHWSNELIA------EQLQQQVSQLQDQLDA--ELEDK 424

Query: 443 REKKKELEREELWKKLEELKLKKALEK 469
           R+   EL RE+   +  +L++   L+K
Sbjct: 425 RKVLLELSREKAQNEDLKLEVTNILQK 451


>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
          Length = 1220

 Score = 32.3 bits (72), Expect = 0.99
 Identities = 28/93 (30%), Positives = 48/93 (51%), Gaps = 8/93 (8%)

Query: 378 EYILSLIEENIDKILPIMFASLYKISKEHWNPTIVALVYNVLKTLMEMNGKLFDDLTSSY 437
           E +L   ++ ++K LP+ F    + + E  N  +        + L+E   K  + L    
Sbjct: 332 EPVLEDEQQQLEKKLPVTFEDKKRENFERGNLELEKR----RQALLEQQRKEQERLAQLE 387

Query: 438 KAERQREKKKELEREELWKKLEELKLKKALEKQ 470
           +AE++R   KE ER+E  +K  +L+L+K LEKQ
Sbjct: 388 RAEQER---KERERQEQERK-RQLELEKQLEKQ 416


>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
          Length = 1721

 Score = 32.3 bits (72), Expect = 0.99
 Identities = 28/93 (30%), Positives = 48/93 (51%), Gaps = 8/93 (8%)

Query: 378 EYILSLIEENIDKILPIMFASLYKISKEHWNPTIVALVYNVLKTLMEMNGKLFDDLTSSY 437
           E +L   ++ ++K LP+ F    + + E  N  +        + L+E   K  + L    
Sbjct: 332 EPVLEDEQQQLEKKLPVTFEDKKRENFERGNLELEKR----RQALLEQQRKEQERLAQLE 387

Query: 438 KAERQREKKKELEREELWKKLEELKLKKALEKQ 470
           +AE++R   KE ER+E  +K  +L+L+K LEKQ
Sbjct: 388 RAEQER---KERERQEQERK-RQLELEKQLEKQ 416


>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
            transmembrane signal), 1 [Homo sapiens]
          Length = 3259

 Score = 31.6 bits (70), Expect = 1.7
 Identities = 18/70 (25%), Positives = 39/70 (55%), Gaps = 1/70 (1%)

Query: 403  SKEHWNPTIVALVYNVLKTLMEMNGKLFDDLTSSYKAERQREKKKELEREELWKKLEEL- 461
            S EHW P +   +  + K   ++  KL + LTS     ++ ++K+   REEL ++ ++  
Sbjct: 1154 SSEHWKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYN 1213

Query: 462  KLKKALEKQN 471
            +L++  ++Q+
Sbjct: 1214 RLQEQFDEQS 1223


>gi|87116683 proline/serine-rich coiled-coil 2 [Homo sapiens]
          Length = 1989

 Score = 31.2 bits (69), Expect = 2.2
 Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 2/58 (3%)

Query: 420 KTLMEMNGKLFDDLTSSYKAERQREK--KKELEREELWKKLEELKLKKALEKQNSAYN 475
           + L +   K +  L    + ERQ+E+  +K+ E EE  K+ EE++  + L  Q   YN
Sbjct: 429 QALRKQQTKAWKKLQQQKEQERQKEEDQRKQAEEEERRKREEEIRKIRDLSNQEEQYN 486


>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 668

 Score = 30.8 bits (68), Expect = 2.9
 Identities = 12/49 (24%), Positives = 31/49 (63%)

Query: 422 LMEMNGKLFDDLTSSYKAERQREKKKELEREELWKKLEELKLKKALEKQ 470
           + E   K++      ++ E+ RE++K  E+EE+W++ E+++ ++ + +Q
Sbjct: 432 IREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQ 480


>gi|33286444 mastermind-like 2 [Homo sapiens]
          Length = 1156

 Score = 30.8 bits (68), Expect = 2.9
 Identities = 24/75 (32%), Positives = 37/75 (49%), Gaps = 6/75 (8%)

Query: 3   SSSPPAGAASAAISASEKVDGFTRKSVRKAQRQKRSQGSSQFRSQGSQAELHPLPQLKDA 62
           S+ P    A++A+S S  +      SV ++Q Q ++ GS   R+  S  E+    QLK  
Sbjct: 386 SAGPAFSMANSALSTSSPIP-----SVPQSQAQPQT-GSGASRALPSWQEVSHAQQLKQI 439

Query: 63  TSNEQQELFCQKLQQ 77
            +N QQ    Q+ QQ
Sbjct: 440 AANRQQHARMQQHQQ 454


>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
           protein 6 [Homo sapiens]
          Length = 724

 Score = 30.8 bits (68), Expect = 2.9
 Identities = 12/49 (24%), Positives = 31/49 (63%)

Query: 422 LMEMNGKLFDDLTSSYKAERQREKKKELEREELWKKLEELKLKKALEKQ 470
           + E   K++      ++ E+ RE++K  E+EE+W++ E+++ ++ + +Q
Sbjct: 493 IREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQ 541


>gi|115648142 centrosomal protein 164kDa [Homo sapiens]
          Length = 1460

 Score = 30.8 bits (68), Expect = 2.9
 Identities = 33/124 (26%), Positives = 57/124 (45%), Gaps = 10/124 (8%)

Query: 346 KKIEEPLFK---QISKCVSSSHFQVAERALYFWNNEYILS-LIEENIDKILPIMFASLYK 401
           KKI+E   K   Q+ KC+     +V +++ +    E+ LS L+ E   ++       L K
Sbjct: 794 KKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDK 853

Query: 402 ISKEHWNPTIVALVY---NVLKTLMEMNGKLFDDLTSSYKAERQREKKKELEREELWKKL 458
           + +EH      A         K   E+ G L  +L    + +R  E++ E  R+E  K+L
Sbjct: 854 MKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELE---RLQRAHERELETVRQEQHKRL 910

Query: 459 EELK 462
           E+L+
Sbjct: 911 EDLR 914


>gi|209862748 ataxin 3-like [Homo sapiens]
          Length = 355

 Score = 30.8 bits (68), Expect = 2.9
 Identities = 24/96 (25%), Positives = 43/96 (44%)

Query: 389 DKILPIMFASLYKISKEHWNPTIVALVYNVLKTLMEMNGKLFDDLTSSYKAERQREKKKE 448
           D++L I+        K +    +    + V KT++E   +  D+  +S + E   ++  E
Sbjct: 175 DQLLQIISVEEMDTPKLNGKKLVKQKEHRVYKTVLEKVSEESDESGTSDQDEEDFQRALE 234

Query: 449 LEREELWKKLEELKLKKALEKQNSAYNMHSILSNTS 484
           L R+E  ++ E L+    L  Q S+ N    L  TS
Sbjct: 235 LSRQETNREDEHLRSTIELSMQGSSGNTSQDLPKTS 270


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.382 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,726,354
Number of Sequences: 37866
Number of extensions: 713281
Number of successful extensions: 4648
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 37
Number of HSP's that attempted gapping in prelim test: 4456
Number of HSP's gapped (non-prelim): 209
length of query: 486
length of database: 18,247,518
effective HSP length: 106
effective length of query: 380
effective length of database: 14,233,722
effective search space: 5408814360
effective search space used: 5408814360
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.