Search of human proteins with 5453595

Search of human proteins with 5453595

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5453595 adenylyl cyclase-associated protein [Homo sapiens]
         (475 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|157649073 adenylyl cyclase-associated protein [Homo sapiens]       951   0.0  
gi|5453595 adenylyl cyclase-associated protein [Homo sapiens]         951   0.0  
gi|5453593 adenylyl cyclase-associated protein 2 [Homo sapiens]       597   e-171
gi|47132519 Ras association and pleckstrin homology domains 1 is...    49   1e-05
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap...    48   2e-05
gi|148229134 ring finger and KH domain containing 2 [Homo sapiens]     45   1e-04
gi|120587019 zinc finger protein 318 [Homo sapiens]                    44   3e-04
gi|126090663 zinc finger homeodomain 4 [Homo sapiens]                  44   4e-04
gi|4504733 insulin receptor substrate 4 [Homo sapiens]                 43   7e-04
gi|118918413 MICAL C-terminal like [Homo sapiens]                      43   7e-04
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     43   7e-04
gi|11386183 WAS protein family, member 2 [Homo sapiens]                42   0.001
gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]             42   0.001
gi|32880208 diaphanous homolog 3 isoform b [Homo sapiens]              42   0.001
gi|110225351 diaphanous homolog 3 isoform a [Homo sapiens]             42   0.001
gi|62000702 diacylglycerol kinase kappa [Homo sapiens]                 42   0.002
gi|7706687 Enah/Vasp-like [Homo sapiens]                               42   0.002
gi|56549694 enabled homolog isoform a [Homo sapiens]                   41   0.002
gi|39930375 enabled homolog isoform b [Homo sapiens]                   41   0.002
gi|4507869 vasodilator-stimulated phosphoprotein [Homo sapiens]        41   0.002
gi|40353727 synaptopodin isoform A [Homo sapiens]                      41   0.002
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]                    41   0.002
gi|62177127 myosin heavy chain Myr 8 [Homo sapiens]                    41   0.002
gi|239753407 PREDICTED: hypothetical protein [Homo sapiens]            41   0.003
gi|46275820 tetratricopeptide repeat domain 9B [Homo sapiens]          41   0.003
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo...    41   0.003
gi|18959210 WIRE protein [Homo sapiens]                                41   0.003
gi|153792074 proline rich 12 [Homo sapiens]                            41   0.003
gi|119829187 alpha 1 type XVII collagen [Homo sapiens]                 40   0.004
gi|122937271 WAS protein homolog associated with actin, golgi me...    40   0.004

>gi|157649073 adenylyl cyclase-associated protein [Homo sapiens]
          Length = 475

 Score =  951 bits (2458), Expect = 0.0
 Identities = 475/475 (100%), Positives = 475/475 (100%)

Query: 1   MADMQNLVERLERAVGRLEAVSHTSDMHRGYADSPSKAGAAPYVQAFDSLLAGPVAEYLK 60
           MADMQNLVERLERAVGRLEAVSHTSDMHRGYADSPSKAGAAPYVQAFDSLLAGPVAEYLK
Sbjct: 1   MADMQNLVERLERAVGRLEAVSHTSDMHRGYADSPSKAGAAPYVQAFDSLLAGPVAEYLK 60

Query: 61  ISKEIGGDVQKHAEMVHTGLKLERALLVTASQCQQPAENKLSDLLAPISEQIKEVITFRE 120
           ISKEIGGDVQKHAEMVHTGLKLERALLVTASQCQQPAENKLSDLLAPISEQIKEVITFRE
Sbjct: 61  ISKEIGGDVQKHAEMVHTGLKLERALLVTASQCQQPAENKLSDLLAPISEQIKEVITFRE 120

Query: 121 KNRGSKLFNHLSAVSESIQALGWVAMAPKPGPYVKEMNDAAMFYTNRVLKEYKDVDKKHV 180
           KNRGSKLFNHLSAVSESIQALGWVAMAPKPGPYVKEMNDAAMFYTNRVLKEYKDVDKKHV
Sbjct: 121 KNRGSKLFNHLSAVSESIQALGWVAMAPKPGPYVKEMNDAAMFYTNRVLKEYKDVDKKHV 180

Query: 181 DWVKAYLSIWTELQAYIKEFHTTGLAWSKTGPVAKELSGLPSGPSAGSGPPPPPPGPPPP 240
           DWVKAYLSIWTELQAYIKEFHTTGLAWSKTGPVAKELSGLPSGPSAGSGPPPPPPGPPPP
Sbjct: 181 DWVKAYLSIWTELQAYIKEFHTTGLAWSKTGPVAKELSGLPSGPSAGSGPPPPPPGPPPP 240

Query: 241 PVSTSSGSDESASRSALFAQINQGESITHALKHVSDDMKTHKNPALKAQSGPVRSGPKPF 300
           PVSTSSGSDESASRSALFAQINQGESITHALKHVSDDMKTHKNPALKAQSGPVRSGPKPF
Sbjct: 241 PVSTSSGSDESASRSALFAQINQGESITHALKHVSDDMKTHKNPALKAQSGPVRSGPKPF 300

Query: 301 SAPKPQTSPSPKRATKKEPAVLELEGKKWRVENQENVSNLVIEDTELKQVAYIYKCVNTT 360
           SAPKPQTSPSPKRATKKEPAVLELEGKKWRVENQENVSNLVIEDTELKQVAYIYKCVNTT
Sbjct: 301 SAPKPQTSPSPKRATKKEPAVLELEGKKWRVENQENVSNLVIEDTELKQVAYIYKCVNTT 360

Query: 361 LQIKGKINSITVDNCKKLGLVFDDVVGIVEIINSKDVKVQVMGKVPTISINKTDGCHAYL 420
           LQIKGKINSITVDNCKKLGLVFDDVVGIVEIINSKDVKVQVMGKVPTISINKTDGCHAYL
Sbjct: 361 LQIKGKINSITVDNCKKLGLVFDDVVGIVEIINSKDVKVQVMGKVPTISINKTDGCHAYL 420

Query: 421 SKNSLDCEIVSAKSSEMNVLIPTEGGDFNEFPVPEQFKTLWNGQKLVTTVTEIAG 475
           SKNSLDCEIVSAKSSEMNVLIPTEGGDFNEFPVPEQFKTLWNGQKLVTTVTEIAG
Sbjct: 421 SKNSLDCEIVSAKSSEMNVLIPTEGGDFNEFPVPEQFKTLWNGQKLVTTVTEIAG 475


>gi|5453595 adenylyl cyclase-associated protein [Homo sapiens]
          Length = 475

 Score =  951 bits (2458), Expect = 0.0
 Identities = 475/475 (100%), Positives = 475/475 (100%)

Query: 1   MADMQNLVERLERAVGRLEAVSHTSDMHRGYADSPSKAGAAPYVQAFDSLLAGPVAEYLK 60
           MADMQNLVERLERAVGRLEAVSHTSDMHRGYADSPSKAGAAPYVQAFDSLLAGPVAEYLK
Sbjct: 1   MADMQNLVERLERAVGRLEAVSHTSDMHRGYADSPSKAGAAPYVQAFDSLLAGPVAEYLK 60

Query: 61  ISKEIGGDVQKHAEMVHTGLKLERALLVTASQCQQPAENKLSDLLAPISEQIKEVITFRE 120
           ISKEIGGDVQKHAEMVHTGLKLERALLVTASQCQQPAENKLSDLLAPISEQIKEVITFRE
Sbjct: 61  ISKEIGGDVQKHAEMVHTGLKLERALLVTASQCQQPAENKLSDLLAPISEQIKEVITFRE 120

Query: 121 KNRGSKLFNHLSAVSESIQALGWVAMAPKPGPYVKEMNDAAMFYTNRVLKEYKDVDKKHV 180
           KNRGSKLFNHLSAVSESIQALGWVAMAPKPGPYVKEMNDAAMFYTNRVLKEYKDVDKKHV
Sbjct: 121 KNRGSKLFNHLSAVSESIQALGWVAMAPKPGPYVKEMNDAAMFYTNRVLKEYKDVDKKHV 180

Query: 181 DWVKAYLSIWTELQAYIKEFHTTGLAWSKTGPVAKELSGLPSGPSAGSGPPPPPPGPPPP 240
           DWVKAYLSIWTELQAYIKEFHTTGLAWSKTGPVAKELSGLPSGPSAGSGPPPPPPGPPPP
Sbjct: 181 DWVKAYLSIWTELQAYIKEFHTTGLAWSKTGPVAKELSGLPSGPSAGSGPPPPPPGPPPP 240

Query: 241 PVSTSSGSDESASRSALFAQINQGESITHALKHVSDDMKTHKNPALKAQSGPVRSGPKPF 300
           PVSTSSGSDESASRSALFAQINQGESITHALKHVSDDMKTHKNPALKAQSGPVRSGPKPF
Sbjct: 241 PVSTSSGSDESASRSALFAQINQGESITHALKHVSDDMKTHKNPALKAQSGPVRSGPKPF 300

Query: 301 SAPKPQTSPSPKRATKKEPAVLELEGKKWRVENQENVSNLVIEDTELKQVAYIYKCVNTT 360
           SAPKPQTSPSPKRATKKEPAVLELEGKKWRVENQENVSNLVIEDTELKQVAYIYKCVNTT
Sbjct: 301 SAPKPQTSPSPKRATKKEPAVLELEGKKWRVENQENVSNLVIEDTELKQVAYIYKCVNTT 360

Query: 361 LQIKGKINSITVDNCKKLGLVFDDVVGIVEIINSKDVKVQVMGKVPTISINKTDGCHAYL 420
           LQIKGKINSITVDNCKKLGLVFDDVVGIVEIINSKDVKVQVMGKVPTISINKTDGCHAYL
Sbjct: 361 LQIKGKINSITVDNCKKLGLVFDDVVGIVEIINSKDVKVQVMGKVPTISINKTDGCHAYL 420

Query: 421 SKNSLDCEIVSAKSSEMNVLIPTEGGDFNEFPVPEQFKTLWNGQKLVTTVTEIAG 475
           SKNSLDCEIVSAKSSEMNVLIPTEGGDFNEFPVPEQFKTLWNGQKLVTTVTEIAG
Sbjct: 421 SKNSLDCEIVSAKSSEMNVLIPTEGGDFNEFPVPEQFKTLWNGQKLVTTVTEIAG 475


>gi|5453593 adenylyl cyclase-associated protein 2 [Homo sapiens]
          Length = 477

 Score =  597 bits (1540), Expect = e-171
 Identities = 307/479 (64%), Positives = 374/479 (78%), Gaps = 10/479 (2%)

Query: 1   MADMQNLVERLERAVGRLEAVSHTSDMHRGYADSPSK--AGAAPYVQAFDSLLAGPVAEY 58
           MA+MQ LVERLERAV RLE++S  S    G     +   AG AP V+AFD L+   VAE+
Sbjct: 1   MANMQGLVERLERAVSRLESLSAESHRPPGNCGEVNGVIAGVAPSVEAFDKLMDSMVAEF 60

Query: 59  LKISKEIGGDVQKHAEMVHTGLKLERALLVTASQCQQPAENKLSDLLAPISEQIKEVITF 118
           LK S+ + GDV+ HAEMVH+  + +RA L+ ASQ QQP EN ++ LL PISE+I+E+ TF
Sbjct: 61  LKNSRILAGDVETHAEMVHSAFQAQRAFLLMASQYQQPHENDVAALLKPISEKIQEIQTF 120

Query: 119 REKNRGSKLFNHLSAVSESIQALGWVAMAPKPGPYVKEMNDAAMFYTNRVLKEYKDVDKK 178
           RE+NRGS +FNHLSAVSESI ALGW+A++PKPGPYVKEMNDAA FYTNRVLK+YK  D +
Sbjct: 121 RERNRGSNMFNHLSAVSESIPALGWIAVSPKPGPYVKEMNDAATFYTNRVLKDYKHSDLR 180

Query: 179 HVDWVKAYLSIWTELQAYIKEFHTTGLAWSKTGPVAKELSG---LPSGPSAGSGPPP-PP 234
           HVDWVK+YL+IW+ELQAYIKE HTTGL WSKTGPVA  +S    L SGP     PPP PP
Sbjct: 181 HVDWVKSYLNIWSELQAYIKEHHTTGLTWSKTGPVASTVSAFSVLSSGPGLPPPPPPLPP 240

Query: 235 PGPPPPPVSTSSGSDESASRSALFAQINQGESITHALKHVSDDMKTHKNPALKAQSGPVR 294
           PGPPP   +     + S SRSALFAQ+NQGE+IT  L+HV+DD KT+KNP+L+AQ G  +
Sbjct: 241 PGPPPLFENEGKKEESSPSRSALFAQLNQGEAITKGLRHVTDDQKTYKNPSLRAQGGQTQ 300

Query: 295 SGPKPFSAPKPQTSPSPKRATKKEPAVLELEGKKWRVENQENVSNLVIEDTELKQVAYIY 354
           S P     P P TSP    + K  P VLELEGKKWRVE QE+ ++LVI +TELKQVAYI+
Sbjct: 301 S-PTKSHTPSP-TSPKSYPSQKHAP-VLELEGKKWRVEYQEDRNDLVISETELKQVAYIF 357

Query: 355 KCVNTTLQIKGKINSITVDNCKKLGLVFDDVVGIVEIINSKDVKVQVMGKVPTISINKTD 414
           KC  +T+QIKGK+NSI +DNCKKLGLVFD+VVGIVE+INS+D+++QVMG+VPTISINKT+
Sbjct: 358 KCEKSTIQIKGKVNSIIIDNCKKLGLVFDNVVGIVEVINSQDIQIQVMGRVPTISINKTE 417

Query: 415 GCHAYLSKNSLDCEIVSAKSSEMNVLIPTEGGDFNEFPVPEQFKTLWNGQKLVTTVTEI 473
           GCH YLS+++LDCEIVSAKSSEMN+LIP + GD+ EFP+PEQFKT W+G KL+T   EI
Sbjct: 418 GCHIYLSEDALDCEIVSAKSSEMNILIP-QDGDYREFPIPEQFKTAWDGSKLITEPAEI 475


>gi|47132519 Ras association and pleckstrin homology domains 1
           isoform 1 [Homo sapiens]
          Length = 1250

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 32/111 (28%), Positives = 44/111 (39%), Gaps = 7/111 (6%)

Query: 221 PSGPSAGSGPPPPPPGPPPPPVSTSSGSDESASRSALFAQINQGESITHALKHVSDDMKT 280
           P  P     PPPPPP PPPPP   S  +  + S + +F + +    + +A +H     K 
Sbjct: 627 PLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKP 686

Query: 281 HKNPALKAQS-------GPVRSGPKPFSAPKPQTSPSPKRATKKEPAVLEL 324
              P +++QS        P    P P   P P T  S     K  P    L
Sbjct: 687 PTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSL 737



 Score = 38.1 bits (87), Expect = 0.018
 Identities = 35/114 (30%), Positives = 46/114 (40%), Gaps = 24/114 (21%)

Query: 230  PPPPP---PGPPPPPVSTSSGS-DESASRSALFAQINQGESITHALKHVSDDMKTHKNPA 285
            PPPPP   P PPPPP  T+S + D+S S         +  S T +           +N +
Sbjct: 928  PPPPPSPVPAPPPPPPPTASPTPDKSGSP-------GKKTSKTSSPGGKKPPPTPQRNSS 980

Query: 286  LKAQSGPVRSGPK---------PFSAPKPQTSPS----PKRATKKEPAVLELEG 326
            +K+ SG     PK          F+ P    SPS    P  A   +P  L L G
Sbjct: 981  IKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSG 1034



 Score = 37.0 bits (84), Expect = 0.039
 Identities = 34/124 (27%), Positives = 47/124 (37%), Gaps = 3/124 (2%)

Query: 201 HTTGLAWSKTGPVAKELSGLPSGPSAGSGPPPPPPGPPPPPVSTSSGSDESASRSALFAQ 260
           H+  L    T PV +  S  P      +G  PPPP PPPPP   S+ +    +  A    
Sbjct: 679 HSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCA--PS 736

Query: 261 INQGESITHALKHVSDDMKTHKNPALKAQSGPVRSGPKPFSAPKP-QTSPSPKRATKKEP 319
           + Q  +    LK       T   P       P+ +   P + PKP  T P+P       P
Sbjct: 737 LPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAP 796

Query: 320 AVLE 323
            V +
Sbjct: 797 VVTQ 800



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 23/103 (22%), Positives = 37/103 (35%), Gaps = 2/103 (1%)

Query: 221  PSGPSAGSGPPPPPPGP-PPPPVSTSSGSDESASRSALFAQINQGESITHALKHVSDDMK 279
            PS PS    PPPPP    P PP+   +    + S           +    ++K      +
Sbjct: 1065 PSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTR 1124

Query: 280  THKNPALKAQSGPVRSGPKPFSAPKPQTSPSPKRATKKEPAVL 322
              +N + +     +   P   +   PQ   SPK +   +P  L
Sbjct: 1125 PKRNDSTRLTQAEISEQP-TMATVVPQVPTSPKSSLSVQPGFL 1166


>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
           sapiens]
          Length = 505

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 39/127 (30%), Positives = 57/127 (44%), Gaps = 12/127 (9%)

Query: 210 TGPVAKELSGLPSGPSAGSGPPPPPP--GPPPPPVSTSSGSDE----SASRSALFAQINQ 263
           +GP     S L  GP A   PPPPPP  GPPPPP   S G  +    + +++AL  QI +
Sbjct: 356 SGPPPPPPSVLGVGPVAPPPPPPPPPPPGPPPPPGLPSDGDHQVPTTAGNKAALLDQIRE 415

Query: 264 GESITHALKHVSDDMKTHKNPALKAQSGPVRSG--PKPFSAPKPQTSPSPKRATKKEPAV 321
           G      LK V  + +        A    +R G   K  +  +  T P+P   +    A+
Sbjct: 416 GAQ----LKKVEQNSRPVSCSGRDALLDQIRQGIQLKSVADGQESTPPTPAPTSGIVGAL 471

Query: 322 LELEGKK 328
           +E+  K+
Sbjct: 472 MEVMQKR 478



 Score = 38.1 bits (87), Expect = 0.018
 Identities = 48/186 (25%), Positives = 67/186 (36%), Gaps = 35/186 (18%)

Query: 194 QAYIKEFHTTGLAWS---KTGPVAKELSGL-----PSGPSAGSGPPPPPP-----GPPPP 240
           +A +K+  T+ + +    KTG V    + L     P  P +  GPPPPPP     GPPPP
Sbjct: 243 EAQLKDRETSKVIYDFIEKTGGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPPPP 302

Query: 241 PVSTSSGSDESASRSALFAQINQGESITHAL--KHVSDDMKTHKNPALKAQS-------- 290
           P           SR+   A      S           + M     PAL + +        
Sbjct: 303 PARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPP 362

Query: 291 ------GPVRSGPKPFSAPKPQTSPSPKRATKKEPAVLELEGKKWRVENQENVSNLVIED 344
                 GPV   P P   P P   P P   +  +  V    G K  + +Q      + E 
Sbjct: 363 PSVLGVGPVAPPPPPPPPPPPGPPPPPGLPSDGDHQVPTTAGNKAALLDQ------IREG 416

Query: 345 TELKQV 350
            +LK+V
Sbjct: 417 AQLKKV 422


>gi|148229134 ring finger and KH domain containing 2 [Homo sapiens]
          Length = 659

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 40/140 (28%), Positives = 56/140 (40%), Gaps = 18/140 (12%)

Query: 220 LPSGPSAGSG---------PPPPPPGPPPPPVSTSSGSDESASRSALFAQINQGESITHA 270
           +PSG SA             PPPPP PPPPP+   SG  E      L  +         A
Sbjct: 1   MPSGSSAALALAAAPAPLPQPPPPPPPPPPPLPPPSGGPELEGDGLLLRE-------RLA 53

Query: 271 LKHVSDDMKTHKN-PALKAQSGPVRSGPKPFSAPKPQTSPSPKRATKKEPAVLELEGKKW 329
              + D        PAL+A +   +   +  +   P+    P R    E A LELE  + 
Sbjct: 54  ALGLDDPSPAEPGAPALRAPAAAAQGQARRAAELSPEERAPPGRPGAPEAAELELEEDEE 113

Query: 330 RVENQENVSNLVIEDTELKQ 349
             E  E   +L +E+ EL++
Sbjct: 114 EGEEAELDGDL-LEEEELEE 132


>gi|120587019 zinc finger protein 318 [Homo sapiens]
          Length = 2279

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 24/91 (26%), Positives = 42/91 (46%), Gaps = 8/91 (8%)

Query: 230  PPPPPPGPPPPPVSTSSGSDESASRSALFAQINQGESITHALK--HVSDDMKTHKNPALK 287
            PPPPPP PPPPPV     +  +A  +A+ A +     ++  L    V  ++    NP L 
Sbjct: 1445 PPPPPPPPPPPPVIPHPAAPSAAQANAILAPVKSNPVVSQTLSPGFVGPNI---LNPVLP 1501

Query: 288  AQSGPVRSGPKPFSAPKPQTSPSPKRATKKE 318
                 + +  +P + P  +T+P    + + +
Sbjct: 1502 V---AIMASAQPAAIPSDETAPGVSESDRDQ 1529



 Score = 33.5 bits (75), Expect = 0.43
 Identities = 21/50 (42%), Positives = 23/50 (46%), Gaps = 5/50 (10%)

Query: 211 GPVAKELSGLPSGPSAGSGPPPPPPG-----PPPPPVSTSSGSDESASRS 255
           GP +   SG  SGP+  S PPPPP G     P   P S S      AS S
Sbjct: 22  GPRSGRSSGSSSGPARRSSPPPPPSGSSSRTPARRPRSPSGHRGRRASPS 71


>gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
          Length = 3571

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 21/53 (39%), Positives = 26/53 (49%)

Query: 204  GLAWSKTGPVAKELSGLPSGPSAGSGPPPPPPGPPPPPVSTSSGSDESASRSA 256
            G   S T   A  LS  P+ P   + PPPPPP PPPP  S S    E  ++ +
Sbjct: 3092 GFPTSATSSPALSLSSAPTKPLLQTPPPPPPPPPPPPSSSLSGQQTEQQNKES 3144



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 22/71 (30%), Positives = 33/71 (46%), Gaps = 9/71 (12%)

Query: 177  KKHVDWVKAYLSIWTELQAYIKEFHTTGLAWSKTGPVAKELSGLPSGPSAGSGPPPPPPG 236
            K H + V      +  L+ + +++     A+ K  P++      PS P     PPPPPP 
Sbjct: 1917 KSHQEHVHGQFFPYAALEKFARQYRE---AYDKLYPIS------PSSPETPPPPPPPPPL 1967

Query: 237  PPPPPVSTSSG 247
            PP PP  +S G
Sbjct: 1968 PPAPPQPSSMG 1978



 Score = 36.6 bits (83), Expect = 0.051
 Identities = 15/29 (51%), Positives = 16/29 (55%)

Query: 213  VAKELSGLPSGPSAGSGPPPPPPGPPPPP 241
            V+  L   P  P     PPPPPP PPPPP
Sbjct: 1986 VSTPLQAPPPTPPPPPPPPPPPPPPPPPP 2014



 Score = 36.6 bits (83), Expect = 0.051
 Identities = 14/23 (60%), Positives = 15/23 (65%)

Query: 221  PSGPSAGSGPPPPPPGPPPPPVS 243
            P+ P     PPPPPP PPPPP S
Sbjct: 1995 PTPPPPPPPPPPPPPPPPPPPPS 2017



 Score = 33.9 bits (76), Expect = 0.33
 Identities = 12/17 (70%), Positives = 13/17 (76%)

Query: 230  PPPPPPGPPPPPVSTSS 246
            PPPPPP PPPPP   S+
Sbjct: 2002 PPPPPPPPPPPPPPPSA 2018



 Score = 30.0 bits (66), Expect = 4.8
 Identities = 15/34 (44%), Positives = 17/34 (50%), Gaps = 5/34 (14%)

Query: 208  SKTGPVAKELSGLPSGPSAGSGPPPPPPGPPPPP 241
            S  GPV      +P+  S     PPP P PPPPP
Sbjct: 1975 SSMGPVK-----IPNTVSTPLQAPPPTPPPPPPP 2003


>gi|4504733 insulin receptor substrate 4 [Homo sapiens]
          Length = 1257

 Score = 42.7 bits (99), Expect = 7e-04
 Identities = 16/35 (45%), Positives = 22/35 (62%)

Query: 230 PPPPPPGPPPPPVSTSSGSDESASRSALFAQINQG 264
           PPPPPP PPPPP   + G  +S  R  L+  +++G
Sbjct: 628 PPPPPPPPPPPPAGGTGGKGKSGGRFRLYFCVDRG 662


>gi|118918413 MICAL C-terminal like [Homo sapiens]
          Length = 695

 Score = 42.7 bits (99), Expect = 7e-04
 Identities = 38/151 (25%), Positives = 66/151 (43%), Gaps = 18/151 (11%)

Query: 228 SGPPPPPPGPPPPPVSTSSGSDESASRSALFAQINQGESITHALKHVSDDMKTHKNPALK 287
           + PPPPPP PPPPP  T+ G+D  +    L AQ+ +  S   +    S D +     +L+
Sbjct: 455 AAPPPPPPPPPPPPPPTAGGAD--SKNFPLRAQVTEASSSASSTSSSSADEEFDPQLSLQ 512

Query: 288 AQSGPVRSGPKPFSAPKPQTSPSPKRATKKEPAVLELEGKKWRVENQENVSNLVIEDTEL 347
            +        K     + +   + K+  K+E   L+   K   ++ Q       +E+ E 
Sbjct: 513 LKE-------KKTLRRRKKLEKAMKQLVKQEE--LKRLYKAQAIQRQ-------LEEVEE 556

Query: 348 KQVAYIYKCVNTTLQIKGKINSITVDNCKKL 378
           +Q A   + V     ++G+ +S T D  + L
Sbjct: 557 RQRASEIQGVRLEKALRGEADSGTQDEAQLL 587


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 42.7 bits (99), Expect = 7e-04
 Identities = 26/96 (27%), Positives = 39/96 (40%), Gaps = 8/96 (8%)

Query: 225 SAGSGPPPPPPGPPPPPVSTSSGSDESASRSALFA--------QINQGESITHALKHVSD 276
           +A +  PPP P PPPPP   ++ +   A R+A  A            G     A    + 
Sbjct: 121 AAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAP 180

Query: 277 DMKTHKNPALKAQSGPVRSGPKPFSAPKPQTSPSPK 312
                  PA+   +GP R+ P   +A +P   P P+
Sbjct: 181 PPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQ 216



 Score = 30.8 bits (68), Expect = 2.8
 Identities = 31/129 (24%), Positives = 47/129 (36%), Gaps = 9/129 (6%)

Query: 212 PVAKELSGLPSGPSAGSGPPPPPPGPPPPPVSTSSGSDESASRSALFAQINQGESITHAL 271
           PVA          +A +   PP PGP  P           A R+A  A      +   A+
Sbjct: 139 PVAAAAPARAPRAAAAAATAPPSPGPAQP--------GPRAQRAAPLAAPPPAPAAPPAV 190

Query: 272 KHVSDDMKTHKNPALKAQSGPVRSGPKPFSAPKPQTSPSPKRATKKEPAVLELEGKKWRV 331
              +   +    PA+ A+  P+   P+P + P+ Q  P P+     E   +   G    V
Sbjct: 191 APPAGPRRA-PPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGAVRAGGAARPV 249

Query: 332 ENQENVSNL 340
             +E V  L
Sbjct: 250 SLREVVRYL 258



 Score = 29.6 bits (65), Expect = 6.3
 Identities = 17/45 (37%), Positives = 19/45 (42%), Gaps = 8/45 (17%)

Query: 205 LAWSKTGPVAKELSGLPSGP--------SAGSGPPPPPPGPPPPP 241
           LA     P A      P+GP        +A   P PPPP PP PP
Sbjct: 177 LAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPP 221


>gi|11386183 WAS protein family, member 2 [Homo sapiens]
          Length = 498

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 23/69 (33%), Positives = 35/69 (50%), Gaps = 13/69 (18%)

Query: 212 PVAKELSGLPSGPSAGSGPPPPPPGPPPPPVSTSSG--------SDESASRSALFAQINQ 263
           P+++   G P  P     PPPPPPGPPPPP + + G        SD +  +S+L A  + 
Sbjct: 382 PLSQPTGGAPPPP-----PPPPPPGPPPPPFTGADGQPAIPPPLSDTTKPKSSLPAVSDA 436

Query: 264 GESITHALK 272
              +  A++
Sbjct: 437 RSDLLSAIR 445



 Score = 38.5 bits (88), Expect = 0.013
 Identities = 31/112 (27%), Positives = 36/112 (32%), Gaps = 11/112 (9%)

Query: 219 GLPSGPSAGSGPPPPPP---------GPPPPPVSTSSGSDESASRSALFAQINQGESITH 269
           G P GP  G  PPP PP          PPPPPV   S           F       +   
Sbjct: 307 GSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPP 366

Query: 270 ALKHVSDDMKTHKNPALKAQSGPVRSGPKPFSAPKPQTSPSPKRATKKEPAV 321
                + D  T   P L   +G     P P   P P   P P      +PA+
Sbjct: 367 PPPPPAADYPTLPPPPLSQPTGGAPPPPPP--PPPPGPPPPPFTGADGQPAI 416



 Score = 33.5 bits (75), Expect = 0.43
 Identities = 16/31 (51%), Positives = 18/31 (58%), Gaps = 1/31 (3%)

Query: 212 PVAKELSGLPSGP-SAGSGPPPPPPGPPPPP 241
           P A +   LP  P S  +G  PPPP PPPPP
Sbjct: 370 PPAADYPTLPPPPLSQPTGGAPPPPPPPPPP 400


>gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]
          Length = 502

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 26/74 (35%), Positives = 31/74 (41%), Gaps = 21/74 (28%)

Query: 206 AWSKTGPVAKELSGLPSGPSAGSGPPPPPPGPPPPPVSTSSGS---------------DE 250
           A  ++GP+       P  P AG  P PPPP PPPPP S+ +G                  
Sbjct: 374 ATGRSGPLP------PPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPALVPAGGLAP 427

Query: 251 SASRSALFAQINQG 264
              R AL  QI QG
Sbjct: 428 GGGRGALLDQIRQG 441



 Score = 35.8 bits (81), Expect = 0.087
 Identities = 15/39 (38%), Positives = 21/39 (53%)

Query: 209 KTGPVAKELSGLPSGPSAGSGPPPPPPGPPPPPVSTSSG 247
           ++GP+     G+   P    GPPPP  G PPPP   ++G
Sbjct: 338 RSGPLPPVPLGIAPPPPTPRGPPPPGRGGPPPPPPPATG 376


>gi|32880208 diaphanous homolog 3 isoform b [Homo sapiens]
          Length = 849

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 31/98 (31%), Positives = 44/98 (44%), Gaps = 9/98 (9%)

Query: 154 VKEMNDAAMFYTNRVLKEYKDVDKKHVDWVKAYLSI---WTELQAYIKEFHTTGLAWSKT 210
           ++E  + A     +  KE+ D  +   +  K    I     ELQA+  +F       +  
Sbjct: 239 LEEFEEKASELYKKFEKEFTDHQETQAELQKKEAKINELQAELQAFKSQFGALPADCNIP 298

Query: 211 GPVAKE----LSGLPSGPS--AGSGPPPPPPGPPPPPV 242
            P +KE     S LP  P   +G G PPPPP PPPPP+
Sbjct: 299 LPPSKEGGTGHSALPPPPPLPSGGGVPPPPPPPPPPPL 336


>gi|110225351 diaphanous homolog 3 isoform a [Homo sapiens]
          Length = 1193

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 31/98 (31%), Positives = 44/98 (44%), Gaps = 9/98 (9%)

Query: 154 VKEMNDAAMFYTNRVLKEYKDVDKKHVDWVKAYLSI---WTELQAYIKEFHTTGLAWSKT 210
           ++E  + A     +  KE+ D  +   +  K    I     ELQA+  +F       +  
Sbjct: 502 LEEFEEKASELYKKFEKEFTDHQETQAELQKKEAKINELQAELQAFKSQFGALPADCNIP 561

Query: 211 GPVAKE----LSGLPSGPS--AGSGPPPPPPGPPPPPV 242
            P +KE     S LP  P   +G G PPPPP PPPPP+
Sbjct: 562 LPPSKEGGTGHSALPPPPPLPSGGGVPPPPPPPPPPPL 599


>gi|62000702 diacylglycerol kinase kappa [Homo sapiens]
          Length = 1271

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 27/90 (30%), Positives = 37/90 (41%), Gaps = 10/90 (11%)

Query: 230 PPPPPPGPPPPPVSTSSGSDESASRSALFAQINQGESITHALKHVSDDMKTHKNPALKAQ 289
           PPPPPP PPP P   S  S E         ++  G     A    + ++ T   P    +
Sbjct: 32  PPPPPPAPPPAPPLLSEASPEPIPEPC--PELAPG-PCPEATSESATELYTEPTPEPATE 88

Query: 290 SGPVRSGPKPFSAPKPQTSPSPKRATKKEP 319
                  P    AP+P T P+P+ AT+  P
Sbjct: 89  -------PASEPAPEPATEPAPEPATEPAP 111



 Score = 37.7 bits (86), Expect = 0.023
 Identities = 25/104 (24%), Positives = 40/104 (38%), Gaps = 7/104 (6%)

Query: 221 PSGPSAGSGPPPPPPGPPPPPVSTSSGSDESASRSALFAQINQGESITHALKHVSDDMKT 280
           P  P     PPPPP  PP PP+ + +  +         A     E+ + +   +  +   
Sbjct: 24  PEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATSESATELYTE--P 81

Query: 281 HKNPALKAQSGP-----VRSGPKPFSAPKPQTSPSPKRATKKEP 319
              PA +  S P         P+P + P P+ +P P   +  EP
Sbjct: 82  TPEPATEPASEPAPEPATEPAPEPATEPAPEPAPEPATESAPEP 125



 Score = 36.2 bits (82), Expect = 0.067
 Identities = 24/98 (24%), Positives = 38/98 (38%), Gaps = 12/98 (12%)

Query: 223 GPSAGSGPPPPPPGPPPPPVSTSSGSDESASRSALFAQINQGESITHALKHVSDDMKTHK 282
           G      P PPPP PPPPP      +    S           E+    +     ++    
Sbjct: 17  GEQPAESPEPPPPWPPPPPPPAPPPAPPLLS-----------EASPEPIPEPCPELAPGP 65

Query: 283 NPALKAQSG-PVRSGPKPFSAPKPQTSPSPKRATKKEP 319
            P   ++S   + + P P  A +P + P+P+ AT+  P
Sbjct: 66  CPEATSESATELYTEPTPEPATEPASEPAPEPATEPAP 103


>gi|7706687 Enah/Vasp-like [Homo sapiens]
          Length = 418

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 49/174 (28%), Positives = 59/174 (33%), Gaps = 49/174 (28%)

Query: 208 SKTGPVAK--ELSGLPSGPSAGSGPPPPPPGP---------PPPPVSTSSG-----SDES 251
           S TGP+      S   S P + SGPPPPPP P         PPPP    +G     S + 
Sbjct: 160 SATGPILPPGHPSSAASAPVSCSGPPPPPPPPVPPPPTGATPPPPPPLPAGGAQGSSHDE 219

Query: 252 ASRSALFAQINQGESITHALKHV-----SDDMKTHKNPALKAQSG--------------- 291
           +S S L A I  G  +    +       S    T K+ A +A SG               
Sbjct: 220 SSMSGLAAAI-AGAKLRRVQRPEDASGGSSPSGTSKSDANRASSGGGGGGLMEEMNKLLA 278

Query: 292 -----------PVRSGPKPFSAPKPQTSPSP-KRATKKEPAVLELEGKKWRVEN 333
                      P            P TSPSP  RA  + P   E   K W   N
Sbjct: 279 KRRKAASQSDKPAEKKEDESQMEDPSTSPSPGTRAASQPPNSSEAGRKPWERSN 332


>gi|56549694 enabled homolog isoform a [Homo sapiens]
          Length = 591

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 17/28 (60%), Positives = 19/28 (67%)

Query: 220 LPSGPSAGSGPPPPPPGPPPPPVSTSSG 247
           LP GP+  S   PPPPGPPPPP   S+G
Sbjct: 319 LPPGPAQASVALPPPPGPPPPPPLPSTG 346



 Score = 33.1 bits (74), Expect = 0.57
 Identities = 14/26 (53%), Positives = 15/26 (57%), Gaps = 5/26 (19%)

Query: 221 PSGPSAGSGPPPPPPGPP-----PPP 241
           P  P   +GPPPPPP PP     PPP
Sbjct: 338 PPPPLPSTGPPPPPPPPPLPNQVPPP 363



 Score = 32.3 bits (72), Expect = 0.96
 Identities = 15/29 (51%), Positives = 15/29 (51%), Gaps = 8/29 (27%)

Query: 221 PSGPSAGSGPPPPPP--------GPPPPP 241
           P  PS G  PPPPPP         PPPPP
Sbjct: 340 PPLPSTGPPPPPPPPPLPNQVPPPPPPPP 368



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 40/179 (22%), Positives = 71/179 (39%), Gaps = 18/179 (10%)

Query: 221 PSGPSAGSGPPPPPPGPPPPPVSTS-----SGSDESASRSALFAQINQGESITHALKHVS 275
           P  P   +  PPPPP PP PP+  S     S S+++   + L A I   +     +  + 
Sbjct: 351 PPPPPLPNQVPPPPPPPPAPPLPASGFFLASMSEDNRPLTGLAAAIAGAK--LRKVSRME 408

Query: 276 DDMKTHKNPALKAQSGPVR------SGPKPFSAPKPQTSPSP----KRATKKEPAVLELE 325
           D        A+   S   +      +GP P          S     +R   ++ + +E E
Sbjct: 409 DTSFPSGGNAIGVNSASSKTDTGRGNGPLPLGGSGLMEEMSALLARRRRIAEKGSTIETE 468

Query: 326 GKKWRVENQENVSNLVIEDTELKQVAYIYKCVNTTLQIKGKINSITVDNCKKLGLVFDD 384
            K+ + E+ E V++     +  +     ++  NT    K  + S   D+ +K  +VFD+
Sbjct: 469 QKEDKGEDSEPVTSKASSTSTPEPTRKPWERTNTMNGSKSPVIS-RRDSPRKNQIVFDN 526



 Score = 31.2 bits (69), Expect = 2.1
 Identities = 15/30 (50%), Positives = 16/30 (53%), Gaps = 7/30 (23%)

Query: 219 GLPSGPSAGSGPPPPPPGP-------PPPP 241
           G+  GP A   PPP PPGP       PPPP
Sbjct: 305 GIVLGPLAPPPPPPLPPGPAQASVALPPPP 334


>gi|39930375 enabled homolog isoform b [Homo sapiens]
          Length = 570

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 17/28 (60%), Positives = 19/28 (67%)

Query: 220 LPSGPSAGSGPPPPPPGPPPPPVSTSSG 247
           LP GP+  S   PPPPGPPPPP   S+G
Sbjct: 319 LPPGPAQASVALPPPPGPPPPPPLPSTG 346



 Score = 33.1 bits (74), Expect = 0.57
 Identities = 14/26 (53%), Positives = 15/26 (57%), Gaps = 5/26 (19%)

Query: 221 PSGPSAGSGPPPPPPGPP-----PPP 241
           P  P   +GPPPPPP PP     PPP
Sbjct: 338 PPPPLPSTGPPPPPPPPPLPNQVPPP 363



 Score = 32.3 bits (72), Expect = 0.96
 Identities = 15/29 (51%), Positives = 15/29 (51%), Gaps = 8/29 (27%)

Query: 221 PSGPSAGSGPPPPPP--------GPPPPP 241
           P  PS G  PPPPPP         PPPPP
Sbjct: 340 PPLPSTGPPPPPPPPPLPNQVPPPPPPPP 368



 Score = 31.2 bits (69), Expect = 2.1
 Identities = 15/30 (50%), Positives = 16/30 (53%), Gaps = 7/30 (23%)

Query: 219 GLPSGPSAGSGPPPPPPGP-------PPPP 241
           G+  GP A   PPP PPGP       PPPP
Sbjct: 305 GIVLGPLAPPPPPPLPPGPAQASVALPPPP 334



 Score = 30.8 bits (68), Expect = 2.8
 Identities = 12/25 (48%), Positives = 14/25 (56%)

Query: 221 PSGPSAGSGPPPPPPGPPPPPVSTS 245
           P  P   +  PPPPP PP PP+  S
Sbjct: 351 PPPPPLPNQVPPPPPPPPAPPLPAS 375


>gi|4507869 vasodilator-stimulated phosphoprotein [Homo sapiens]
          Length = 380

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 20/39 (51%), Positives = 22/39 (56%), Gaps = 4/39 (10%)

Query: 218 SGLPSGPSAGSGPPPP----PPGPPPPPVSTSSGSDESA 252
           +G P  P AG  PPPP    PPGPPPPP    SG   +A
Sbjct: 159 AGGPPAPPAGGPPPPPGPPPPPGPPPPPGLPPSGVPAAA 197



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 14/29 (48%), Positives = 19/29 (65%)

Query: 213 VAKELSGLPSGPSAGSGPPPPPPGPPPPP 241
           + + +S     P+  +G PPPPPGPPPPP
Sbjct: 152 IERRVSNAGGPPAPPAGGPPPPPGPPPPP 180



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 34/105 (32%), Positives = 41/105 (39%), Gaps = 25/105 (23%)

Query: 211 GPVAKELSGLPS--GPSAGSGPPPPP---------------PGPPP-PPVSTSSGSDESA 252
           GP A    G P   GP    GPPPPP                GPPP PP+  + G     
Sbjct: 161 GPPAPPAGGPPPPPGPPPPPGPPPPPGLPPSGVPAAAHGAGGGPPPAPPLPAAQGPGGGG 220

Query: 253 SRSALFAQINQGESITHALKHVSDDMKTHKNP-ALKAQSGPVRSG 296
           + +   A    G      L+ VS   +    P A KA+SG  RSG
Sbjct: 221 AGAPGLAAAIAGAK----LRKVSKQEEASGGPTAPKAESG--RSG 259



 Score = 29.3 bits (64), Expect = 8.2
 Identities = 28/108 (25%), Positives = 35/108 (32%), Gaps = 7/108 (6%)

Query: 204 GLAWSKTGPVAKELSGLPSGPSAGSGPPPPPPGPPPPPVSTSSGSDESASRSALFAQINQ 263
           GL +      A+  +G+ S   A  G  PPPP P  P  S  +G            Q   
Sbjct: 90  GLNFGSKEDAAQFAAGMASALEALEGGGPPPP-PALPTWSVPNGPSPEEVEQQKRQQPGP 148

Query: 264 GESITHALKHVSDDMKTHKNPALKAQSGPVRSGPKPFSAPKPQTSPSP 311
            E I   + +          PA  A   P   GP P   P P     P
Sbjct: 149 SEHIERRVSNAGGP------PAPPAGGPPPPPGPPPPPGPPPPPGLPP 190


>gi|40353727 synaptopodin isoform A [Homo sapiens]
          Length = 903

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 34/108 (31%), Positives = 44/108 (40%), Gaps = 14/108 (12%)

Query: 221 PSGPSAGSGPPPPPPGPPPPPVSTSSGSDESASRSALFAQINQGESITHALKHVSDDMKT 280
           P  P  GS    PPP PPPPP+S  S S+ S S      +         AL       + 
Sbjct: 707 PWEPGRGSSMSSPPPLPPPPPMS-PSWSERSVSPLRPETEARPPSRQLQALL-----ARN 760

Query: 281 HKNPALKAQSGPVRSG---PKPFSAPK-----PQTSPSPKRATKKEPA 320
             N A +  + P  +G   P+PFS P+     P   P P R    +PA
Sbjct: 761 IINAARRKSASPRSAGAENPRPFSPPRAPPPPPPPPPPPPRMRSPQPA 808



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 15/36 (41%), Positives = 20/36 (55%)

Query: 218 SGLPSGPSAGSGPPPPPPGPPPPPVSTSSGSDESAS 253
           S LP+GPS+ + P  P P PP P +   S +D   S
Sbjct: 826 SPLPAGPSSCTSPRSPLPAPPRPFLYRRSPTDSDVS 861



 Score = 29.3 bits (64), Expect = 8.2
 Identities = 16/40 (40%), Positives = 18/40 (45%)

Query: 222 SGPSAGSGPPPPPPGPPPPPVSTSSGSDESASRSALFAQI 261
           S P A   PPPPPP PP       +    +A   A FA I
Sbjct: 784 SPPRAPPPPPPPPPPPPRMRSPQPARPGSAAVPGAAFAPI 823


>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
          Length = 1489

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 26/95 (27%), Positives = 38/95 (40%), Gaps = 3/95 (3%)

Query: 217 LSGLPSGPSAGSGPPPPPPGPPPPPVSTSSGSDESASRSALFAQINQGESITHALKHVSD 276
           L G  +    G GPPP PP PPPPP    + +D +AS     A  + G  ++       D
Sbjct: 765 LMGAAAPQYPGRGPPPAPPPPPPPP---RAPADPAASPDPPSAVASPGSGLSSPGPKPGD 821

Query: 277 DMKTHKNPALKAQSGPVRSGPKPFSAPKPQTSPSP 311
                + P     + P     +    P+P+  P P
Sbjct: 822 SGYETETPFSPEGAFPGGGAAEEEGVPRPRAPPEP 856



 Score = 29.6 bits (65), Expect = 6.3
 Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 9/84 (10%)

Query: 221 PSGPSAGSGPPPPPPGPPPPPVSTSSGSDESASRSALFAQINQGESITHALKHVSDDMKT 280
           P  P  G+  PPP PGP P P     G  E   +     Q++  + +    + V+ ++  
Sbjct: 854 PEPPDPGAPRPPPDPGPLPLP-----GPRE---KPTFVVQVSTEQLLMSLREDVTRNLLG 905

Query: 281 HKNPALKAQSGPVRSGPKPFSAPK 304
            K  A   ++GP ++G  P +  K
Sbjct: 906 EKG-ATARETGPRKAGRGPGNREK 928


>gi|62177127 myosin heavy chain Myr 8 [Homo sapiens]
          Length = 1858

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 33/103 (32%), Positives = 44/103 (42%), Gaps = 11/103 (10%)

Query: 218  SGLPSGPSAGSGPPPPPPGPPPPPVSTSSGSDESASRSALFAQINQGESITHALKHVSDD 277
            SG  S PS    PPPPPPGPPP P    +      +     A +N G++   A     + 
Sbjct: 1564 SGRASPPSTPP-PPPPPPGPPPAPYRPCA----HLAFPPEPAPVNAGKAGPSA-----EA 1613

Query: 278  MKTHKNPALKAQSGPVRSGPK-PFSAPKPQTSPSPKRATKKEP 319
             K H  P     +GP  S PK P+S  K   + + K  +   P
Sbjct: 1614 PKVHPKPNSAPVAGPCSSFPKIPYSPVKATRADARKAGSSASP 1656


>gi|239753407 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 182

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 34/123 (27%), Positives = 46/123 (37%), Gaps = 14/123 (11%)

Query: 211 GPVAKELSGLPSGPSAGSGPPPPPPGPPPPPVSTSSGS--------DESASRSALFAQIN 262
           GP A   SG+  G    +    PPP P  P  S+SSGS          SA +  L + + 
Sbjct: 19  GPQAARRSGVQGGQRNSTSARAPPPPPLAPSSSSSSGSSGSSGGGGSGSAGQPTLGSMLA 78

Query: 263 QGESITHALKHVSDD------MKTHKNPALKAQSGPVRSGPKPFSAPKPQTSPSPKRATK 316
            G +   A +                 P L     P + GPK  ++P+P  SP P   T 
Sbjct: 79  VGSAARRASERAGGRAGGTALRAREPPPPLLPPPSPPQPGPKGPASPRPLPSPLPLLETT 138

Query: 317 KEP 319
             P
Sbjct: 139 PFP 141


>gi|46275820 tetratricopeptide repeat domain 9B [Homo sapiens]
          Length = 239

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 37/108 (34%), Positives = 50/108 (46%), Gaps = 3/108 (2%)

Query: 217 LSGLPSGPSAGSGPPPPPPGPPPPPVSTSSGSDESASRSALFAQINQGESITHALKHVSD 276
           LS   SGP +GS      PGP P P S S G+   +S  A  A   +G+      K    
Sbjct: 26  LSPPGSGPGSGSRHGSARPGPTPEP-SGSLGAALDSSLRAAVAFKAEGQRCYREKKFREA 84

Query: 277 DMKTHKN-PALKAQSGPVRSGPKPFSAPKPQTSPSPKRATKKEPAVLE 323
             K H+    LKA  G   SG  P  AP P +SP P R ++++  ++E
Sbjct: 85  IGKYHRALLQLKAAQGARPSG-LPAPAPGPTSSPGPARLSEEQRRLVE 131


>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
           sapiens]
          Length = 483

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 27/92 (29%), Positives = 37/92 (40%), Gaps = 6/92 (6%)

Query: 220 LPSGPSAGSGPPPPPPGPPPPPVSTSS-GSDESASRSALFAQINQGESITHALKHVSDDM 278
           LP  P     PPPPPP  PP    TSS    +   RSAL A I QG  +    +     +
Sbjct: 11  LPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKVTQ-----I 65

Query: 279 KTHKNPALKAQSGPVRSGPKPFSAPKPQTSPS 310
                P +++  G  + G    +     T P+
Sbjct: 66  NDRSAPQIESSKGTNKEGGGSANTRGASTPPT 97



 Score = 35.4 bits (80), Expect = 0.11
 Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 1/51 (1%)

Query: 208 SKTGPVAKELSGLPSGPSAGSGPPPPPPGPP-PPPVSTSSGSDESASRSAL 257
           S  GP+ K    + + P   + PPPPPP PP PPP+  +S   + A +  L
Sbjct: 202 SPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQL 252



 Score = 32.7 bits (73), Expect = 0.74
 Identities = 13/26 (50%), Positives = 17/26 (65%)

Query: 221 PSGPSAGSGPPPPPPGPPPPPVSTSS 246
           P+ P+     PPPPP P PPP+ +SS
Sbjct: 169 PNVPAPPPPTPPPPPPPLPPPLPSSS 194



 Score = 31.2 bits (69), Expect = 2.1
 Identities = 11/20 (55%), Positives = 13/20 (65%)

Query: 222 SGPSAGSGPPPPPPGPPPPP 241
           + P   + P PPPP PPPPP
Sbjct: 164 TAPPRPNVPAPPPPTPPPPP 183



 Score = 29.6 bits (65), Expect = 6.3
 Identities = 17/57 (29%), Positives = 25/57 (43%), Gaps = 1/57 (1%)

Query: 224 PSAGSGPPPPPPGPPPPPVSTSSGSDESASRSALFAQINQGESITHALKHVSDDMKT 280
           P AG G   PPP PP    +T   S +S   +A       G  + +   H+ DD ++
Sbjct: 366 PGAGGGKLNPPPAPPARSPTTEL-SSKSQQATAWTPTQQPGGQLRNGSLHIIDDFES 421


>gi|18959210 WIRE protein [Homo sapiens]
          Length = 440

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 19/45 (42%), Positives = 23/45 (51%), Gaps = 7/45 (15%)

Query: 230 PPPPPPGPPPPPVSTSSGS-------DESASRSALFAQINQGESI 267
           PPPPPPGPPPPP    + +       DE   R AL   I +G  +
Sbjct: 6   PPPPPPGPPPPPTFHQANTEQPKLSRDEQRGRGALLQDICKGTKL 50



 Score = 35.4 bits (80), Expect = 0.11
 Identities = 30/100 (30%), Positives = 38/100 (38%), Gaps = 30/100 (30%)

Query: 222 SGPSAGSGPPPPPP--GPPPPPVSTSSGSDESASRSALFAQINQGESITHALKHVSDDMK 279
           +GPS  S  PPPPP   PP  P   SS ++ESA                        ++ 
Sbjct: 241 TGPSGQSLAPPPPPYRQPPGVPNGPSSPTNESA-----------------------PELP 277

Query: 280 THKNPALKAQSGPVRSGPKPFSAPKPQTSPSPKRATKKEP 319
              N   +   GPVR       AP P TS SP   + + P
Sbjct: 278 QRHNSLHRKTPGPVRG-----LAPPPPTSASPSLLSNRPP 312



 Score = 35.4 bits (80), Expect = 0.11
 Identities = 16/34 (47%), Positives = 18/34 (52%), Gaps = 8/34 (23%)

Query: 224 PSAGSGPPPPPP--------GPPPPPVSTSSGSD 249
           PS G+ PPPPPP         PPPPP     GS+
Sbjct: 319 PSRGAAPPPPPPVIRNGARDAPPPPPPYRMHGSE 352



 Score = 33.9 bits (76), Expect = 0.33
 Identities = 17/40 (42%), Positives = 19/40 (47%), Gaps = 6/40 (15%)

Query: 224 PSAGSGPPPP------PPGPPPPPVSTSSGSDESASRSAL 257
           PS G  PPPP      PP PPPPP+        +  RS L
Sbjct: 354 PSRGKPPPPPSRTPAGPPPPPPPPLRNGHRDSITTVRSFL 393


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 17/34 (50%), Positives = 20/34 (58%)

Query: 214  AKELSGLPSGPSAGSGPPPPPPGPPPPPVSTSSG 247
            A+ L  + SGP   + PPPPPP PPP P S   G
Sbjct: 1024 AEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKG 1057



 Score = 38.5 bits (88), Expect = 0.013
 Identities = 27/79 (34%), Positives = 35/79 (44%), Gaps = 6/79 (7%)

Query: 220 LPSGPSAGSGPPPPPPGPPPPPVSTSSGSDESASRSALFAQINQGESITHALKHVSDDMK 279
           L   PS   GPP PP GPPPP ++T         +  L+    QGE       H S  + 
Sbjct: 469 LSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGV--QGEPYPGPAAH-SQGLP 525

Query: 280 THKNPALKAQSG--PVRSG 296
           T  +P+L   +G  P  SG
Sbjct: 526 T-ASPSLSYSTGHSPALSG 543



 Score = 35.8 bits (81), Expect = 0.087
 Identities = 28/105 (26%), Positives = 38/105 (36%), Gaps = 15/105 (14%)

Query: 207  WSKTGPVAKELSGLPSGPSAGSGPPPPPPG-PPPPPVSTSSGSDESASRSALFAQINQGE 265
            + K GP   E       P AG+GPPP PP   P  P      S        L    N+  
Sbjct: 962  YGKAGPPEDE-----GDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPP 1016

Query: 266  SITHALKHVSDDMKTHKNPALKAQSGPVRSGPKPFSAPKPQTSPS 310
             +   +         +  P    QSGP ++ P P   P P  +P+
Sbjct: 1017 ELPSTV---------NAEPLGLIQSGPHQAAPPPPPPPPPPPAPA 1052



 Score = 33.9 bits (76), Expect = 0.33
 Identities = 39/140 (27%), Positives = 55/140 (39%), Gaps = 13/140 (9%)

Query: 212  PVAKELSGLPSGP-SAG--SGPPPPPPGPPP----PPVSTSSGSDESASRSAL-FAQINQ 263
            PV    SG    P SAG  S PPP  P PPP    P  +TS    E    +A+      +
Sbjct: 1671 PVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPE 1730

Query: 264  GESITHALKHVSDDMKTHKNP----ALKAQSGPVRSGPKPFSAPKPQTSPSPK-RATKKE 318
              S+   ++   +  K  +        +A SG      +  +  +P TS  PK R TK +
Sbjct: 1731 KPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPKARPTKVK 1790

Query: 319  PAVLELEGKKWRVENQENVS 338
                  + KKW  E   N +
Sbjct: 1791 AEPPPKKRKKWLKEAGGNAT 1810



 Score = 33.1 bits (74), Expect = 0.57
 Identities = 26/91 (28%), Positives = 35/91 (38%), Gaps = 3/91 (3%)

Query: 221 PSGPSAGSGPP--PPPPGPPPPPVSTSSGSDESASRSALFAQINQGESITHALKHVSDDM 278
           P+G      PP  P PP PPPPP    +  +  AS SA  A   Q     +     +   
Sbjct: 216 PAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGP 275

Query: 279 KTHKNPALKAQSGPVRSGPKPFSAPKPQTSP 309
              +  AL  Q   ++   +P SA  P   P
Sbjct: 276 PPPER-ALPRQDTVIKHYQRPASAQPPPPPP 305



 Score = 33.1 bits (74), Expect = 0.57
 Identities = 19/42 (45%), Positives = 21/42 (50%), Gaps = 5/42 (11%)

Query: 205  LAWSKTGPVAKELSGLPSGPSAGSGPPP-----PPPGPPPPP 241
            LA +   P    L GLPS  S G+  PP     PPP PPP P
Sbjct: 1424 LAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAP 1465



 Score = 32.7 bits (73), Expect = 0.74
 Identities = 11/16 (68%), Positives = 13/16 (81%)

Query: 227 GSGPPPPPPGPPPPPV 242
           G+  PPPPP PPPPP+
Sbjct: 831 GAPQPPPPPPPPPPPM 846



 Score = 32.7 bits (73), Expect = 0.74
 Identities = 16/30 (53%), Positives = 16/30 (53%), Gaps = 4/30 (13%)

Query: 220  LPSGPS----AGSGPPPPPPGPPPPPVSTS 245
            LPS P       S PPPPP  PPPPP   S
Sbjct: 1482 LPSPPPLVAPTPSSPPPPPLPPPPPPAMPS 1511



 Score = 32.3 bits (72), Expect = 0.96
 Identities = 14/24 (58%), Positives = 14/24 (58%), Gaps = 3/24 (12%)

Query: 221  PSGPSAGSGPPPPPP---GPPPPP 241
            PS P     PPPPPP    PPPPP
Sbjct: 1493 PSSPPPPPLPPPPPPAMPSPPPPP 1516



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 11/18 (61%), Positives = 12/18 (66%)

Query: 224 PSAGSGPPPPPPGPPPPP 241
           P+   G P PPP PPPPP
Sbjct: 826 PATRDGAPQPPPPPPPPP 843



 Score = 31.2 bits (69), Expect = 2.1
 Identities = 11/20 (55%), Positives = 12/20 (60%)

Query: 221 PSGPSAGSGPPPPPPGPPPP 240
           P+       PPPPPP PPPP
Sbjct: 826 PATRDGAPQPPPPPPPPPPP 845



 Score = 30.4 bits (67), Expect = 3.7
 Identities = 10/13 (76%), Positives = 11/13 (84%)

Query: 230 PPPPPPGPPPPPV 242
           PPPPPP PPP P+
Sbjct: 836 PPPPPPPPPPMPL 848



 Score = 29.6 bits (65), Expect = 6.3
 Identities = 11/21 (52%), Positives = 11/21 (52%)

Query: 221  PSGPSAGSGPPPPPPGPPPPP 241
            P  P     P P PP PPPPP
Sbjct: 1458 PPTPPPAPTPQPQPPPPPPPP 1478



 Score = 29.3 bits (64), Expect = 8.2
 Identities = 14/34 (41%), Positives = 17/34 (50%), Gaps = 6/34 (17%)

Query: 221  PSGPSAGSGPPPPPPGP------PPPPVSTSSGS 248
            P  P+    PPPPPP P      PPP V+ +  S
Sbjct: 1462 PPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSS 1495


>gi|119829187 alpha 1 type XVII collagen [Homo sapiens]
          Length = 1497

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 20/39 (51%), Positives = 21/39 (53%), Gaps = 7/39 (17%)

Query: 219  GLPSGPSAGSGP-------PPPPPGPPPPPVSTSSGSDE 250
            G+PSGPS G          PP PPGPP PP S SS   E
Sbjct: 975  GIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQE 1013



 Score = 29.6 bits (65), Expect = 6.3
 Identities = 14/46 (30%), Positives = 24/46 (52%), Gaps = 5/46 (10%)

Query: 231  PPPPPGPPPPP-----VSTSSGSDESASRSALFAQINQGESITHAL 271
            PP PPGP  PP     +ST +     +S S+  + + +G S + ++
Sbjct: 1266 PPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSM 1311


>gi|122937271 WAS protein homolog associated with actin, golgi
           membranes and microtubules [Homo sapiens]
          Length = 809

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 20/44 (45%), Positives = 26/44 (59%), Gaps = 2/44 (4%)

Query: 214 AKELSGLPSGPSAGSGPPPPPPGPPPPPVSTSSGSDESASRSAL 257
           ++ELS  P  P     PPPPPP PPPPP+   S S ++A+   L
Sbjct: 633 SEELSLPPPPPPPP--PPPPPPPPPPPPLRALSSSSQAATHQNL 674


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.129    0.374 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,145,266
Number of Sequences: 37866
Number of extensions: 1185715
Number of successful extensions: 27760
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 526
Number of HSP's successfully gapped in prelim test: 492
Number of HSP's that attempted gapping in prelim test: 14516
Number of HSP's gapped (non-prelim): 8159
length of query: 475
length of database: 18,247,518
effective HSP length: 106
effective length of query: 369
effective length of database: 14,233,722
effective search space: 5252243418
effective search space used: 5252243418
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.