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Search of human proteins with 54124343
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|54124343 hypothetical protein LOC387680 [Homo sapiens]
(1341 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|54124343 hypothetical protein LOC387680 [Homo sapiens] 2647 0.0
gi|59814411 hypothetical protein LOC253725 [Homo sapiens] 2549 0.0
gi|154090959 hypothetical protein LOC55747 [Homo sapiens] 2443 0.0
gi|169190542 PREDICTED: hypothetical protein [Homo sapiens] 607 e-173
gi|169194762 PREDICTED: hypothetical protein [Homo sapiens] 90 2e-17
gi|56676397 ankyrin repeat domain 11 [Homo sapiens] 65 6e-10
gi|239753231 PREDICTED: ankyrin repeat domain 36 [Homo sapiens] 64 1e-09
gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens] 63 2e-09
gi|217330641 IWS1 homolog [Homo sapiens] 63 2e-09
gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens] 62 4e-09
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 61 8e-09
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 59 2e-08
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 59 2e-08
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 59 2e-08
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu... 57 9e-08
gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH po... 57 9e-08
gi|217035154 RCSD domain containing 1 [Homo sapiens] 57 1e-07
gi|55741677 SET domain containing 1A [Homo sapiens] 55 3e-07
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 55 3e-07
gi|239747798 PREDICTED: hypothetical protein XP_002348316 [Homo ... 54 1e-06
gi|104526627 triadin [Homo sapiens] 54 1e-06
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 53 2e-06
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre... 52 4e-06
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 51 7e-06
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens] 50 2e-05
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens] 50 2e-05
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 49 2e-05
gi|150170670 piccolo isoform 2 [Homo sapiens] 49 3e-05
gi|150378539 piccolo isoform 1 [Homo sapiens] 49 3e-05
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 49 4e-05
>gi|54124343 hypothetical protein LOC387680 [Homo sapiens]
Length = 1341
Score = 2647 bits (6862), Expect = 0.0
Identities = 1341/1341 (100%), Positives = 1341/1341 (100%)
Query: 1 MMNRTTPDQELAPASEPVWERPWSVEEIRRSSQSWSLAADAGLLQFLQEFSQQTISRTHE 60
MMNRTTPDQELAPASEPVWERPWSVEEIRRSSQSWSLAADAGLLQFLQEFSQQTISRTHE
Sbjct: 1 MMNRTTPDQELAPASEPVWERPWSVEEIRRSSQSWSLAADAGLLQFLQEFSQQTISRTHE 60
Query: 61 IKKQVDGLIRETKATDCRLHNVFNDFLMLSNTQFIENRVYDEEVEEPVLKAEAEKTEQEK 120
IKKQVDGLIRETKATDCRLHNVFNDFLMLSNTQFIENRVYDEEVEEPVLKAEAEKTEQEK
Sbjct: 61 IKKQVDGLIRETKATDCRLHNVFNDFLMLSNTQFIENRVYDEEVEEPVLKAEAEKTEQEK 120
Query: 121 TREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYI 180
TREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYI
Sbjct: 121 TREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYI 180
Query: 181 DRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDN 240
DRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDN
Sbjct: 181 DRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDN 240
Query: 241 EQNRHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGD 300
EQNRHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGD
Sbjct: 241 EQNRHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGD 300
Query: 301 AVGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGL 360
AVGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGL
Sbjct: 301 AVGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGL 360
Query: 361 FSGGKGLFDDEDEESDLFTEAPQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFG 420
FSGGKGLFDDEDEESDLFTEAPQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFG
Sbjct: 361 FSGGKGLFDDEDEESDLFTEAPQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFG 420
Query: 421 AASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTA 480
AASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTA
Sbjct: 421 AASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTA 480
Query: 481 DIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSD 540
DIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSD
Sbjct: 481 DIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSD 540
Query: 541 EEDSEDLFSSQSASKLKGASLLPGKLPTLVSLFDDEDEEDNLFGGTAAKKQTLCLQAQRE 600
EEDSEDLFSSQSASKLKGASLLPGKLPTLVSLFDDEDEEDNLFGGTAAKKQTLCLQAQRE
Sbjct: 541 EEDSEDLFSSQSASKLKGASLLPGKLPTLVSLFDDEDEEDNLFGGTAAKKQTLCLQAQRE 600
Query: 601 EKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVK 660
EKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVK
Sbjct: 601 EKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVK 660
Query: 661 KTSLFEEDEEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVS 720
KTSLFEEDEEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVS
Sbjct: 661 KTSLFEEDEEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVS 720
Query: 721 EAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHS 780
EAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHS
Sbjct: 721 EAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHS 780
Query: 781 DLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGRDPDAHPKSTGVF 840
DLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGRDPDAHPKSTGVF
Sbjct: 781 DLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGRDPDAHPKSTGVF 840
Query: 841 QDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEK 900
QDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEK
Sbjct: 841 QDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEK 900
Query: 901 KRVVKKDHSVDSFKNQKHPESIQGSKEKGIWKPETPQDSSGLAPFKTKEPSTRIGKIQAN 960
KRVVKKDHSVDSFKNQKHPESIQGSKEKGIWKPETPQDSSGLAPFKTKEPSTRIGKIQAN
Sbjct: 901 KRVVKKDHSVDSFKNQKHPESIQGSKEKGIWKPETPQDSSGLAPFKTKEPSTRIGKIQAN 960
Query: 961 LAINPAALLPTAASQISEVKPVLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQ 1020
LAINPAALLPTAASQISEVKPVLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQ
Sbjct: 961 LAINPAALLPTAASQISEVKPVLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQ 1020
Query: 1021 ADTLHSANKSRVKMRGKRRPQTRAARRLAAQESSETEDMSVPRGPIAQWADGAISPNGHR 1080
ADTLHSANKSRVKMRGKRRPQTRAARRLAAQESSETEDMSVPRGPIAQWADGAISPNGHR
Sbjct: 1021 ADTLHSANKSRVKMRGKRRPQTRAARRLAAQESSETEDMSVPRGPIAQWADGAISPNGHR 1080
Query: 1081 PQLRAASGEDSTEEALAAAAAPWEGGPVPGVDRSPFAKSLGHSRGEADLFDSGDIFSTGT 1140
PQLRAASGEDSTEEALAAAAAPWEGGPVPGVDRSPFAKSLGHSRGEADLFDSGDIFSTGT
Sbjct: 1081 PQLRAASGEDSTEEALAAAAAPWEGGPVPGVDRSPFAKSLGHSRGEADLFDSGDIFSTGT 1140
Query: 1141 GSQSVERTKPKAKIAENPANPPVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFP 1200
GSQSVERTKPKAKIAENPANPPVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFP
Sbjct: 1141 GSQSVERTKPKAKIAENPANPPVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFP 1200
Query: 1201 LLEDEDDLFTDQKVKKNETKSNSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLES 1260
LLEDEDDLFTDQKVKKNETKSNSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLES
Sbjct: 1201 LLEDEDDLFTDQKVKKNETKSNSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLES 1260
Query: 1261 NLFDDNIDIFADLTVKPKEKSKKKVEAKSIFDDDMDDIFSSGIQAKTTKPKSRSAQAAPE 1320
NLFDDNIDIFADLTVKPKEKSKKKVEAKSIFDDDMDDIFSSGIQAKTTKPKSRSAQAAPE
Sbjct: 1261 NLFDDNIDIFADLTVKPKEKSKKKVEAKSIFDDDMDDIFSSGIQAKTTKPKSRSAQAAPE 1320
Query: 1321 PRFEHKVSNIFDDPLNAFGGQ 1341
PRFEHKVSNIFDDPLNAFGGQ
Sbjct: 1321 PRFEHKVSNIFDDPLNAFGGQ 1341
>gi|59814411 hypothetical protein LOC253725 [Homo sapiens]
Length = 1318
Score = 2549 bits (6607), Expect = 0.0
Identities = 1301/1341 (97%), Positives = 1308/1341 (97%), Gaps = 23/1341 (1%)
Query: 1 MMNRTTPDQELAPASEPVWERPWSVEEIRRSSQSWSLAADAGLLQFLQEFSQQTISRTHE 60
MMNRTTPDQEL PASEPVWERPWSVEEIRRSSQSWSLAADAGLLQFLQEFSQQTISRTHE
Sbjct: 1 MMNRTTPDQELVPASEPVWERPWSVEEIRRSSQSWSLAADAGLLQFLQEFSQQTISRTHE 60
Query: 61 IKKQVDGLIRETKATDCRLHNVFNDFLMLSNTQFIENRVYDEEVEEPVLKAEAEKTEQEK 120
IKKQVDGLIRETKATDCRLHNVFNDFLMLSNTQFIENRVYDEEVEEPVLKAEAEKTEQEK
Sbjct: 61 IKKQVDGLIRETKATDCRLHNVFNDFLMLSNTQFIENRVYDEEVEEPVLKAEAEKTEQEK 120
Query: 121 TREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYI 180
TREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYI
Sbjct: 121 TREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYI 180
Query: 181 DRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDN 240
DRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDN
Sbjct: 181 DRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDN 240
Query: 241 EQNRHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGD 300
EQN+HTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGD
Sbjct: 241 EQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGD 300
Query: 301 AVGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGL 360
A+GRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGL
Sbjct: 301 AMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGL 360
Query: 361 FSGGKGLFDDEDEESDLFTEAPQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFG 420
FSGGKGLFDDEDEESDLFTEA QDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFG
Sbjct: 361 FSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFG 420
Query: 421 AASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTA 480
AASVPS+KEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKT KVQSTA
Sbjct: 421 AASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTA 480
Query: 481 DIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSD 540
DIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLS SKNLKPSSETKTQKGLFSD
Sbjct: 481 DIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSYSKNLKPSSETKTQKGLFSD 540
Query: 541 EEDSEDLFSSQSASKLKGASLLPGKLPTLVSLFDDEDEEDNLFGGTAAKKQTLCLQAQRE 600
EEDSEDLFSSQSAS LKGASLLPGKLPT VSLFDDEDEEDNLFGGTAAKKQTL LQAQRE
Sbjct: 541 EEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQRE 600
Query: 601 EKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVK 660
EKAKASELSKKKASALLFSSDEE WNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVK
Sbjct: 601 EKAKASELSKKKASALLFSSDEE--WNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVK 658
Query: 661 KTSLFEEDEEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVS 720
KTSLFEED+EDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVS
Sbjct: 659 KTSLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVS 718
Query: 721 EAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHS 780
EAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHS
Sbjct: 719 EAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHS 778
Query: 781 DLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGRDPDAHPKSTGVF 840
DLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKG DPDAHPKSTGVF
Sbjct: 779 DLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGCDPDAHPKSTGVF 838
Query: 841 QDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEK 900
QDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEK
Sbjct: 839 QDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEK 898
Query: 901 KRVVKKDHSVDSFKNQKHPESIQGSKEKGIWKPETPQDSSGLAPFKTKEPSTRIGKIQAN 960
KRVVKKDHSV+SFKNQKHPESIQGSKEKGIWKPETP QAN
Sbjct: 899 KRVVKKDHSVNSFKNQKHPESIQGSKEKGIWKPETP---------------------QAN 937
Query: 961 LAINPAALLPTAASQISEVKPVLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQ 1020
LAINPAALLPTAASQISEVKPVLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQ
Sbjct: 938 LAINPAALLPTAASQISEVKPVLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQ 997
Query: 1021 ADTLHSANKSRVKMRGKRRPQTRAARRLAAQESSETEDMSVPRGPIAQWADGAISPNGHR 1080
ADTLHSANKSRVKMRGKRRPQTRAARRLAAQESSE EDMSVPRGPIAQWADGAISPNGHR
Sbjct: 998 ADTLHSANKSRVKMRGKRRPQTRAARRLAAQESSEAEDMSVPRGPIAQWADGAISPNGHR 1057
Query: 1081 PQLRAASGEDSTEEALAAAAAPWEGGPVPGVDRSPFAKSLGHSRGEADLFDSGDIFSTGT 1140
PQLRAASGEDSTEEALAAAAAPWEGGPVPGVD SPFAKSLGHSRGEADLFDSGDIFSTGT
Sbjct: 1058 PQLRAASGEDSTEEALAAAAAPWEGGPVPGVDTSPFAKSLGHSRGEADLFDSGDIFSTGT 1117
Query: 1141 GSQSVERTKPKAKIAENPANPPVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFP 1200
GSQSVERTKPKAKIAENPANPPVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFP
Sbjct: 1118 GSQSVERTKPKAKIAENPANPPVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFP 1177
Query: 1201 LLEDEDDLFTDQKVKKNETKSNSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLES 1260
LLEDEDDLFTDQKVKKNETKS+SQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLES
Sbjct: 1178 LLEDEDDLFTDQKVKKNETKSSSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLES 1237
Query: 1261 NLFDDNIDIFADLTVKPKEKSKKKVEAKSIFDDDMDDIFSSGIQAKTTKPKSRSAQAAPE 1320
NLFDDNIDIFADLTVKPKEKSKKKVEAKSIFDDDMDDIFS+GIQAKTTKPKSRSAQAAPE
Sbjct: 1238 NLFDDNIDIFADLTVKPKEKSKKKVEAKSIFDDDMDDIFSTGIQAKTTKPKSRSAQAAPE 1297
Query: 1321 PRFEHKVSNIFDDPLNAFGGQ 1341
PRFEHKVSNIFDDPLNAFGGQ
Sbjct: 1298 PRFEHKVSNIFDDPLNAFGGQ 1318
>gi|154090959 hypothetical protein LOC55747 [Homo sapiens]
Length = 1253
Score = 2443 bits (6331), Expect = 0.0
Identities = 1240/1244 (99%), Positives = 1240/1244 (99%)
Query: 98 RVYDEEVEEPVLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGN 157
RVYDEEVEEPVLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGN
Sbjct: 10 RVYDEEVEEPVLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGN 69
Query: 158 SDSEEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGS 217
SDSEEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGS
Sbjct: 70 SDSEEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGS 129
Query: 218 IVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEE 277
IVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEE
Sbjct: 130 IVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEE 189
Query: 278 NTRPKRSRPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEE 337
NTRPKRSRPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEE
Sbjct: 190 NTRPKRSRPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEE 249
Query: 338 DNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEAPQDRQAGASVKEESSS 397
DNLF PPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEAPQDRQAGASVKEESSS
Sbjct: 250 DNLFTPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEAPQDRQAGASVKEESSS 309
Query: 398 SKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDGD 457
SKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDGD
Sbjct: 310 SKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDGD 369
Query: 458 DDDDFFSAPHSKPSKTGKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKV 517
DDDDFFSAPHSKPSKTGKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKV
Sbjct: 370 DDDDFFSAPHSKPSKTGKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKV 429
Query: 518 TLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLPTLVSLFDDED 577
TLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLPT VSLFDDED
Sbjct: 430 TLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLPTSVSLFDDED 489
Query: 578 EEDNLFGGTAAKKQTLCLQAQREEKAKASELSKKKASALLFSSDEEDQWNIPASQTHLAS 637
EEDNLFGGTAAKKQTLCLQAQREEKAKASELSKKKASALLFSSDEEDQWNIPASQTHLAS
Sbjct: 490 EEDNLFGGTAAKKQTLCLQAQREEKAKASELSKKKASALLFSSDEEDQWNIPASQTHLAS 549
Query: 638 DSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDEEDDLFAIAKDSQKKTQRVSLLFEDDVDS 697
DSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDEEDDLFAIAKDSQKKTQRVSLLFEDDVDS
Sbjct: 550 DSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDEEDDLFAIAKDSQKKTQRVSLLFEDDVDS 609
Query: 698 GGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGR 757
GSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGR
Sbjct: 610 RGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGR 669
Query: 758 TDVAESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNII 817
TDVAESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNII
Sbjct: 670 TDVAESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNII 729
Query: 818 QAPQKEVGKGRDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGS 877
QAPQKEVGKGRDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGS
Sbjct: 730 QAPQKEVGKGRDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGS 789
Query: 878 LFGDDEDDDLFSSAKSQPLVQEKKRVVKKDHSVDSFKNQKHPESIQGSKEKGIWKPETPQ 937
LFGDDEDDDLFSSAKSQPLVQEKKRVVKKDHSVDSFKNQKHPESIQGSKEKGIWKPETPQ
Sbjct: 790 LFGDDEDDDLFSSAKSQPLVQEKKRVVKKDHSVDSFKNQKHPESIQGSKEKGIWKPETPQ 849
Query: 938 DSSGLAPFKTKEPSTRIGKIQANLAINPAALLPTAASQISEVKPVLPELAFPSSEHRRSH 997
DSSGLAPFKTKEPSTRIGKIQANLAINPAALLPTAASQISEVKPVLPELAFPSSEHRRSH
Sbjct: 850 DSSGLAPFKTKEPSTRIGKIQANLAINPAALLPTAASQISEVKPVLPELAFPSSEHRRSH 909
Query: 998 GLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQTRAARRLAAQESSETE 1057
GLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQTRAARRLAAQESSETE
Sbjct: 910 GLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQTRAARRLAAQESSETE 969
Query: 1058 DMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAAAAPWEGGPVPGVDRSPFA 1117
DMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAAAAPWEGGPVPGVDRSPFA
Sbjct: 970 DMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAAAAPWEGGPVPGVDRSPFA 1029
Query: 1118 KSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANPPVGGKAKSPMFPALGE 1177
KSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANPPVGGKAKSPMFPALGE
Sbjct: 1030 KSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANPPVGGKAKSPMFPALGE 1089
Query: 1178 ASSDDDLFQSAKPKPAKKTNPFPLLEDEDDLFTDQKVKKNETKSNSQQDVILTTQDIFED 1237
ASSDDDLFQSAKPKPAKKTN FPLLEDEDDLFTDQKVKKNETKSNSQQDVILTTQDIFED
Sbjct: 1090 ASSDDDLFQSAKPKPAKKTNTFPLLEDEDDLFTDQKVKKNETKSNSQQDVILTTQDIFED 1149
Query: 1238 DIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPKEKSKKKVEAKSIFDDDMDD 1297
DIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPKEKSKKKVEAKSIFDDDMDD
Sbjct: 1150 DIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPKEKSKKKVEAKSIFDDDMDD 1209
Query: 1298 IFSSGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDDPLNAFGGQ 1341
IFSSGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDDPLNAFGGQ
Sbjct: 1210 IFSSGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDDPLNAFGGQ 1253
>gi|169190542 PREDICTED: hypothetical protein [Homo sapiens]
Length = 308
Score = 607 bits (1565), Expect = e-173
Identities = 304/308 (98%), Positives = 306/308 (99%)
Query: 1034 MRGKRRPQTRAARRLAAQESSETEDMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTE 1093
MRGKRRPQTRAARRLAAQESSE EDMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTE
Sbjct: 1 MRGKRRPQTRAARRLAAQESSEAEDMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTE 60
Query: 1094 EALAAAAAPWEGGPVPGVDRSPFAKSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAK 1153
EALAAAAAPWEGGPVPGVD SPFAKSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAK
Sbjct: 61 EALAAAAAPWEGGPVPGVDTSPFAKSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAK 120
Query: 1154 IAENPANPPVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFPLLEDEDDLFTDQK 1213
IAENPANPPVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFPLLEDEDDLFTDQK
Sbjct: 121 IAENPANPPVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFPLLEDEDDLFTDQK 180
Query: 1214 VKKNETKSNSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADL 1273
VKKNETKS+SQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADL
Sbjct: 181 VKKNETKSSSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADL 240
Query: 1274 TVKPKEKSKKKVEAKSIFDDDMDDIFSSGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDD 1333
TVKPKEKSKKKVEAKSIFDDDMDDIFS+GIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDD
Sbjct: 241 TVKPKEKSKKKVEAKSIFDDDMDDIFSTGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDD 300
Query: 1334 PLNAFGGQ 1341
PLNAFGGQ
Sbjct: 301 PLNAFGGQ 308
Score = 33.9 bits (76), Expect = 1.1
Identities = 46/195 (23%), Positives = 74/195 (37%), Gaps = 28/195 (14%)
Query: 726 LFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHSDLFSS 785
LF + G +SV++ AK + V K + + E DLF S
Sbjct: 96 LFDSGDIFSTGTGSQSVERTKPKAKIAENPANPPVGGKAKSPMFP-ALGEASSDDDLFQS 154
Query: 786 SSPWDKGTKPRTKT-VLSLFDEEEDKMEDQNIIQAPQKEVGKGRDPDAHPKSTGVFQD-- 842
+ P KP KT L ++E+D DQ + + E D + +F+D
Sbjct: 155 AKP-----KPAKKTNPFPLLEDEDDLFTDQKV---KKNETKSSSQQDVILTTQDIFEDDI 206
Query: 843 ---EELLFSHKLQKDN--------DPDVDLFAGT----KKTKLLEPSVGSLFGDDEDDDL 887
E + S K ++ D ++D+FA K+ + S+F DD DD+
Sbjct: 207 FATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPKEKSKKKVEAKSIFDDDM-DDI 265
Query: 888 FSSAKSQPLVQEKKR 902
FS+ + K R
Sbjct: 266 FSTGIQAKTTKPKSR 280
Score = 31.2 bits (69), Expect = 7.0
Identities = 50/216 (23%), Positives = 81/216 (37%), Gaps = 47/216 (21%)
Query: 655 EAKAVKKTSLFEEDEEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATK 714
+AK+ +L E +DDLF AK K L ED+ D LF K
Sbjct: 133 KAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFPLLEDEDD----LF------TDQKVK 182
Query: 715 KKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQ 774
K ET S + +++ L + + + A E++K S+K TR +
Sbjct: 183 KNETKSSS---------QQDVILTTQDIFEDDIFATEAIK-------PSQK----TREKE 222
Query: 775 ETVKHS------DLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGR 828
+T++ + D+F+ + K + S+FD++ D + I K
Sbjct: 223 KTLESNLFDDNIDIFADLTVKPKEKSKKKVEAKSIFDDDMDDIFSTGIQAKTTK------ 276
Query: 829 DPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAG 864
PKS E F HK+ D ++ F G
Sbjct: 277 -----PKSRSAQAAPEPRFEHKVSNIFDDPLNAFGG 307
>gi|169194762 PREDICTED: hypothetical protein [Homo sapiens]
Length = 86
Score = 89.7 bits (221), Expect = 2e-17
Identities = 41/43 (95%), Positives = 42/43 (97%)
Query: 1 MMNRTTPDQELAPASEPVWERPWSVEEIRRSSQSWSLAADAGL 43
MMNRTTPDQEL PASEPVWERPWSVEEIRRSSQSWSLAADAG+
Sbjct: 1 MMNRTTPDQELVPASEPVWERPWSVEEIRRSSQSWSLAADAGV 43
>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
Length = 2663
Score = 64.7 bits (156), Expect = 6e-10
Identities = 183/857 (21%), Positives = 301/857 (35%), Gaps = 160/857 (18%)
Query: 207 EEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDL----- 261
E G DR +++ +E+ + + + AH + ++ + D+ + D G L
Sbjct: 943 ESAEAGRDRKDALESCKERRDGRAKPEEAHREELKECGCESGFKDKSDGDFGKGLEPWER 1002
Query: 262 -FADSEKEEEDIEDIE--ENTRPKRSRPTSFADELAARIKGDAVGRVDEEPTTLPSGEAK 318
EKE++D D E E T+P+R + S + + + + + E K
Sbjct: 1003 HHPAREKEKKDGPDKERKEKTKPERYKEKSSDKDKSEKSILEKCQKDKEFDKCF-----K 1057
Query: 319 PRKTLKEK--------KERRTPSDD-EEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFD 369
+K KEK KER+ D +E A P + EDFS D
Sbjct: 1058 EKKDTKEKHKDTHGKDKERKASLDQGKEKKEKAFPGIISEDFSEKKD------------D 1105
Query: 370 DEDEE-----SDLFTEAPQDRQ---AGASVKEESSSSKP---GKKIPAGAVSVFLGDTDV 418
+ +E +D+FT+ +D + G+ K +S P G + + D
Sbjct: 1106 KKGKEKSWYIADIFTDESEDDRDSCMGSGFKMGEASDLPRTDGLQEKEEGREAYASDRH- 1164
Query: 419 FGAASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTG---- 474
+S E QK ++P R+ G G D + F K K
Sbjct: 1165 -RKSSDKQHPERQKDKEPRDRRKDRGAADAGR------DKKEKVFEKHKEKKDKESTEKY 1217
Query: 475 ---KVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSET 531
K +++ D D++ K+K E + D+ K++ ++K SK K S
Sbjct: 1218 KDRKDRASVDSTQDKKN---KQKLPEKAEKKHAAEDKAKSKHKEKSDKEHSKERKSSRSA 1274
Query: 532 KTQKGLFSD---------EEDSEDLFSSQSASKLKGASLLPGKLPTLVSLFDDEDEEDNL 582
+K L EDS D S S+ PG L F + +D
Sbjct: 1275 DAEKSLLEKLEEEALHEYREDSNDKISEVSSDSFTDRGQEPGLTAFLEVSFTEPPGDDK- 1333
Query: 583 FGGTAAKKQTLCLQAQREEKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSK 642
+++ CL EK K E + +S+ S D E A + D +
Sbjct: 1334 ------PRESACLP----EKLKEKERHRHSSSSSKKSHDRERAKKEKAEKKEKGEDYKEG 1383
Query: 643 GEPRDSGTLQSQEAKAVKKTSLFEEDEEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLF 702
G +DSG + E+D L A D+ + + ED++D LF
Sbjct: 1384 GSRKDSG-----------------QYEKDFLEA---DAYGVSYNMKADIEDELDKTIELF 1423
Query: 703 GSPPTSVPPATKKKETVSEAPPLLFSDEEEK---EAQLGVKSVDKKVESAKESLKFGRTD 759
+ KK + SE P ++E K + + + KK E +E + +
Sbjct: 1424 ST--------EKKDKNDSEREPSKKIEKELKPYGSSAINILKEKKKREKHREKWRDEKER 1475
Query: 760 VAESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQA 819
+ +GLL E ++H + DK + PR +DK D+
Sbjct: 1476 HRDRHADGLLRHHRDELLRHHRDEQKPATRDKDSPPRVL---------KDKSRDEGPRLG 1526
Query: 820 PQKEVGKGRDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLF 879
K K +D K V + K+ DP G K + E +G
Sbjct: 1527 DAKLKEKFKDGAEKEKGDPVKMSNG---NDKVAPSKDP------GKKDARPREKLLG--- 1574
Query: 880 GDDEDDDL----FSSAKSQPLVQEKKRVVKKDHSVDSFKNQKHPESIQGSKEKGIWKPET 935
D DL F SQ ++ ++R + + + +H KEK KP
Sbjct: 1575 ----DGDLMMTSFERMLSQKDLEIEERHKRHKERMKQMEKLRHRSGDPKLKEKA--KPAD 1628
Query: 936 PQDSSGL-APFKTK---EPSTRIGKIQANLAINPAA---LLPTAASQISE------VKPV 982
GL P K +P + K++ + I PAA L P + + + +K V
Sbjct: 1629 DGRKKGLDIPAKKPPGLDPPFKDKKLKESTPIPPAAENKLHPASGADSKDWLAGPHMKEV 1688
Query: 983 LPELAFPSSEHRRSHGL 999
LP A P + R G+
Sbjct: 1689 LP--ASPRPDQSRPTGV 1703
Score = 32.0 bits (71), Expect = 4.1
Identities = 62/329 (18%), Positives = 131/329 (39%), Gaps = 33/329 (10%)
Query: 497 ASPEATVSQTDENKA--RAEKKVTLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSAS 554
A+ + S TD++ R + T+SS + SS + + + + E D SS +
Sbjct: 530 AAQKQNPSHTDQHTKHWRTDNWKTISSPAWSEVSSLSDSTRTRLTSESDYSSEGSSVESL 589
Query: 555 K--------LKGASLLPGKLPTLVSLFDDEDEEDNLFGGTAAKKQTLCLQAQREEKAKAS 606
K K ASL K P L S + D G KK + + +EK + S
Sbjct: 590 KPVRKRQEHRKRASLSEKKSPFLSSAEGAVPKLDK--EGKVVKKHKTKHKHKNKEKGQCS 647
Query: 607 ELSKKKASALLFSSDEEDQWNIPAS--QTHLASDSRSKGEPRDSGTLQSQEAKAVKKTSL 664
+ K + + ++ Q + A + L+++++ K D + +E K S
Sbjct: 648 ISQELKLKSFTYEYEDSKQKSDKAILLENDLSTENKLKVLKHDRDHFKKEE-----KLSK 702
Query: 665 FEEDEEDDLFAIAKDSQK---KTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVSE 721
+ +E++ LF K ++ + +S F ++ D + + K+++ E
Sbjct: 703 MKLEEKEWLFKDEKSLKRIKDTNKDISRSFREEKDRSNK-------AEKERSLKEKSPKE 755
Query: 722 APPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHSD 781
L+ +E +K+++ ++KK + ++ + + + + +KE L D
Sbjct: 756 EKLRLYKEERKKKSKDRPSKLEKKNDLKEDKISKEKEKIFKEDKEKLKKEKVYREDSAFD 815
Query: 782 LFSSSSPWDKGTKPRTKTVLSLFDEEEDK 810
+ + + + T SL D++ D+
Sbjct: 816 EYCNKNQF----LENEDTKFSLSDDQRDR 840
>gi|239753231 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
Length = 948
Score = 63.5 bits (153), Expect = 1e-09
Identities = 140/676 (20%), Positives = 251/676 (37%), Gaps = 93/676 (13%)
Query: 329 RRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGL------FDDEDEESDLFTEAP 382
RRT S +NL A + + + GK L + E+ LFT
Sbjct: 149 RRTISQQSAENLDAACGIDKTENGNMFEDQNVDKEGKALPATGQKANVSPEQPPLFTHTV 208
Query: 383 QDRQAGAS-----VKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEP-QKPEQP 436
+DR ++ + +SS + ++ P +++ D PS K ++ + P
Sbjct: 209 KDRDHISTRFLGGMDSLTSSEESSERPPLSTLTLKEAD---------PSSKAAMRRKDSP 259
Query: 437 TPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKP-------SKTGKVQSTADIFGDEEGD 489
P K P DD D + + P K ++T+D D +
Sbjct: 260 PPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDE-KDSVSN 318
Query: 490 LFKEKAVASPEATVSQTDENKARA--EKKVTL--------SSSKNLKPSSETKTQKGLFS 539
+ E TVS ++ + +KKV+L K+ SS+ + S
Sbjct: 319 IATEIKKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKATS 378
Query: 540 DEEDSEDLFSSQSASKLKGASLLPGKLPTLVSLFDDEDEEDNLF--------GGTAAKKQ 591
D+ DS +++ L+ ++ K P L + D+ED N+ GT + ++
Sbjct: 379 DKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQK 438
Query: 592 TLCLQAQREEK-------------AKASELSKKKASALLFSSDEEDQWNIPASQTHLASD 638
L+A +EK K+ +S +K AL +SDEE + S
Sbjct: 439 QPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGS---------VLSI 489
Query: 639 SRSKGEPRDSGTLQSQEAKAVKKTSLFEEDEEDDLFAIAKD------SQKKTQRVSLLFE 692
+R + S T+ S++ A K TS DE+D I + S+K + + +
Sbjct: 490 ARENKDGEKSRTVSSRKKPASKATS----DEKDSFSNITRGKKDGEISRKVSSQKPPTLK 545
Query: 693 DDVDSGGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAK-- 750
D S+ G + K + SE PP L + +EK++ L + K E K
Sbjct: 546 GTSDEEDSVLGIAREN-KDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRV 604
Query: 751 ESLKFGRTDVAESEKEGL--LTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEE 808
S K + EK+ +TR ++ + S P KGT +VL + E +
Sbjct: 605 SSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENK 664
Query: 809 DKMEDQNIIQAPQKEVGKGRDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKT 868
D + + + + +K G D + + ++ + P K T
Sbjct: 665 DGEKSRTV--SSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPT-----LKAT 717
Query: 869 KLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEKKRVVKKDHSVDSFKNQKHPESIQ--GSK 926
E SV S+ +++D + + S+ K +KD ++ + +K+ E + S+
Sbjct: 718 SDEEDSVLSIARENKDGEKSRTVSSEKPSGLKATSAEKDSVLNIARGKKYGEKTKRVSSR 777
Query: 927 EKGIWKPETPQDSSGL 942
+K K + + S L
Sbjct: 778 KKPALKATSDEKDSVL 793
Score = 45.1 bits (105), Expect = 5e-04
Identities = 97/474 (20%), Positives = 176/474 (37%), Gaps = 68/474 (14%)
Query: 196 QEDVGLGELSSEEGSVGS--------DRGSIVDTEEEKEEEESDEDFAHHSDNEQNRHTT 247
Q+ L S EEGSV S ++ V + ++ + + ++ S+ + +
Sbjct: 471 QKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNITRGKKDG 530
Query: 248 QMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDAVGRVDE 307
++S + L S++E+ + EN ++SR S + D V
Sbjct: 531 EISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLN 590
Query: 308 EPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGL 367
GE R + ++K SD+++ + D + S S KG
Sbjct: 591 IARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKP-PALKGT 649
Query: 368 FDDEDEESDLFTEAPQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSM 427
D+ED + E + G + SS PG K + SV ++
Sbjct: 650 SDEEDSVLGIARE----NKDGEKSRTVSSEKPPGLKATSDEKD------------SVLNI 693
Query: 428 KEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGDEE 487
+K + T S PP D++D S ++ +K G+ T + ++
Sbjct: 694 ARGKKDGEKTRTVSSQKPPTLKA----TSDEEDSVLSI--ARENKDGEKSRT--VSSEKP 745
Query: 488 GDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSDEEDSEDL 547
L KA ++ + +V K EK +SS K KP+ + SDE+DS
Sbjct: 746 SGL---KATSAEKDSVLNIARGKKYGEKTKRVSSRK--KPALKAT------SDEKDSVLY 794
Query: 548 FSSQSASKLKGASLLPGKLPTLVSLFDDEDEEDNLFGGTAAKKQTLCLQAQREEKAKASE 607
+ + K ++ K P L ++ D ED N + +++++ +
Sbjct: 795 IAREKKDGEKSRTVSSQKQPALKAICDKEDSVPN-------------MATEKKDEQISGT 841
Query: 608 LSKKKASALLFSSDEEDQ-WNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVK 660
+S +K AL +SD++D NIP + + SGT+ Q+ A K
Sbjct: 842 VSSQKQPALKATSDKKDSVSNIPTEIK----------DGQQSGTVSPQKQSAQK 885
>gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
Length = 1524
Score = 63.2 bits (152), Expect = 2e-09
Identities = 138/669 (20%), Positives = 259/669 (38%), Gaps = 98/669 (14%)
Query: 329 RRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGL------FDDEDEESDLFTEAP 382
RRT S +NL A + + + GK L + E+ LFT
Sbjct: 149 RRTISQQSAENLDAACGIDKTENGNMFEDQNVDKEGKALPATGQKANVSPEQPPLFTHTV 208
Query: 383 QDRQAGAS-----VKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEP-QKPEQP 436
+DR ++ + +SS + ++ P +++ D PS K ++ + P
Sbjct: 209 KDRDHISTRFLGGMDSLTSSEESSERPPLSTLTLKEAD---------PSSKAAMRRKDSP 259
Query: 437 TPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKP-------SKTGKVQSTADIFGDEEGD 489
P K P DD D + + P K ++T+D D +
Sbjct: 260 PPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDE-KDSVSN 318
Query: 490 LFKEKAVASPEATVSQTDEN--KARAEKKVTL--------SSSKNLKPSSETKTQKGLFS 539
+ E TVS ++ K +KKV+L K+ SS+ + S
Sbjct: 319 IATEIKKGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKATS 378
Query: 540 DEEDSEDLFSSQSASKLKGASLLPGKLPTLVSLFDDEDEEDNLFGGTAAKKQTLCLQAQR 599
D+ DS +++ L+ ++ K P L + D+ED N + +
Sbjct: 379 DKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSN-------------IATEI 425
Query: 600 EEKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAV 659
++ K+ +S +K AL ++DE+D S +++A++ + + SGT+ SQ+ A+
Sbjct: 426 KDGEKSGTVSSQKQPALKATTDEKD------SVSNIATEIK---DGEKSGTVSSQKPPAL 476
Query: 660 KKTSLFEEDEEDDLFAIAKDSQ--KKTQRVS-------LLFEDDVDSGGSLFGSPPTSVP 710
TS DEE + +IA++++ +K++ VS D+ DS F +
Sbjct: 477 TATS----DEEGSVLSIARENKDGEKSRTVSSRKKPALKATSDEKDS----FSNITRGKK 528
Query: 711 PATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLT 770
++ S+ PP L +E+++ LG+ +K E ++ SEK L
Sbjct: 529 DGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSR---------TVSSEKPPGLK 579
Query: 771 RSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQK-EVGKGRD 829
S+ E ++ +K + ++ SL ++K NI + + E+ +
Sbjct: 580 ASSAEKDSVLNIARGKKDGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVS 639
Query: 830 PDAHPKSTGVFQDEE-LLFSHKLQKDNDPDVDLFA----GTKKTKLLEPSVGSLFGDDED 884
P G +E+ +L + KD + + + G K T + SV ++ +D
Sbjct: 640 SQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKD 699
Query: 885 DDLFSSAKSQPLVQEKKRVVKKDHSVDSFKNQKHPESIQGS----KEKGIWKPETPQDSS 940
+ + S P K + K+ SV + +K E I G+ K+ + +DS
Sbjct: 700 GEK-TRTVSSPKQPALKAICDKEDSVPNMATEKKDEQISGTVSCQKQPALKATSDKKDSV 758
Query: 941 GLAPFKTKE 949
P + K+
Sbjct: 759 SNIPTEIKD 767
Score = 40.8 bits (94), Expect = 0.009
Identities = 81/366 (22%), Positives = 143/366 (39%), Gaps = 54/366 (14%)
Query: 365 KGLFDDEDEESDLFTEAPQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASV 424
K D++D S++ TE ++G ++ + +S+ + D + +V
Sbjct: 443 KATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTV 502
Query: 425 PSMKEPQ-----------------KPEQPTPRKSPYGPPPT--GLFDDDDG------DDD 459
S K+P K + RK PPT G D++D ++
Sbjct: 503 SSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENK 562
Query: 460 DDFFSAPHSKPSKTGKVQSTAD-------IFGDEEGDLFKE---KAVASPEATVSQTDE- 508
D S S G S+A+ G ++G+ K + S EAT + D
Sbjct: 563 DGEKSRTVSSEKPPGLKASSAEKDSVLNIARGKKDGEKTKRVSSRKKPSLEATSDEKDSF 622
Query: 509 -NKARAEKKVTLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLP 567
N R +K +S + S + KG SDEEDS + ++ K ++ K P
Sbjct: 623 SNITREKKDGEISRKVS---SQKPPALKGT-SDEEDSVLGIARENKDGEKSRTVSSEKPP 678
Query: 568 TLVSLFDDEDEEDNLFGGTAAKKQTLCLQAQREEKAKA---------SELSKKKASALLF 618
L + D++D N+ G ++T + + ++ KA + ++KK +
Sbjct: 679 GLKATSDEKDSVLNIARGKKDGEKTRTVSSPKQPALKAICDKEDSVPNMATEKKDEQISG 738
Query: 619 SSDEEDQWNIPASQTHLASDSRSKGEPRD---SGTLQSQEAKAVKKTSLFEEDEEDDLFA 675
+ + Q + A+ S S E +D SGT+ SQ+ A K TS+ ++D ++
Sbjct: 739 TVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSV-KKDSVSNIAT 797
Query: 676 IAKDSQ 681
KD Q
Sbjct: 798 EIKDGQ 803
>gi|217330641 IWS1 homolog [Homo sapiens]
Length = 819
Score = 63.2 bits (152), Expect = 2e-09
Identities = 98/385 (25%), Positives = 145/385 (37%), Gaps = 92/385 (23%)
Query: 95 IENRVYDEEVEEPVLK--AEAEKTEQEKTR-EQKEVDLIPKVQEAVNYGL-----QVLDS 146
++ ++ D E EEP +++E E K R E + +PK Q + + Q DS
Sbjct: 178 LKPQISDSESEEPPRHQASDSENEEPPKPRMSDSESEELPKPQVSDSESEEPPRHQASDS 237
Query: 147 AFEQLDIKAGNSDSEEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSS 206
E+L K SDSE +D E ++L P P + S E ED + S
Sbjct: 238 ENEELP-KPRISDSESEDPPRHQASDSENEEL----PKPRISDS----ESEDPPRNQASD 288
Query: 207 EEG------------SVGSDRGSIVDTEEE-----KEEEESDEDF--------------A 235
E S G +G D+E E K++ ESD+D +
Sbjct: 289 SENEELPKPRVSDSESEGPQKGPASDSETEDASRHKQKPESDDDSDRENKGEDTEMQNDS 348
Query: 236 HHSDNEQNRHTTQMSDEEEDDDGCDLFADSEKEEE---------------DIEDIEENTR 280
HSD+ +R SD EE++ E E+E D ED EE
Sbjct: 349 FHSDSHMDRKKFHSSDSEEEEHKKQKMDSDEDEKEGEEEKVAKRKAAVLSDSED-EEKAS 407
Query: 281 PKRSRPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRKTLKEKKERR-------TPS 333
K+SR S AD+ + D G+ E T E + K L +KK + S
Sbjct: 408 AKKSRVVSDADDSDSDAVSDKSGK--REKTIASDSEEEAGKELSDKKNEEKDLFGSDSES 465
Query: 334 DDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEAPQDRQAGASVKE 393
+EE+NL A FG G D+E+EE F + + + G + +
Sbjct: 466 GNEEENLIA---------DIFGESG----------DEEEEEFTGFNQEDLEEEKGETQVK 506
Query: 394 ESSSSKPGKKIPAGAVSVFLGDTDV 418
E+ S I G FL D ++
Sbjct: 507 EAEDSDSDDNIKRGKHMDFLSDFEM 531
Score = 55.8 bits (133), Expect = 3e-07
Identities = 127/578 (21%), Positives = 204/578 (35%), Gaps = 112/578 (19%)
Query: 189 GSKLFMEQEDVGL-GELSSEEGSVGSDRGSIV-DTEEEKEEEESDEDFAHHSDNEQNRHT 246
G+ ++ D G GE E GSD GS+ +E E + E HH + +N
Sbjct: 15 GATPVQDERDSGSDGEDDVNEQHSGSDTGSVERHSENETSDREDGLPKGHHVTDSENDEP 74
Query: 247 TQM--SDEEEDDDGCDLFADSEKEE-----------EDIEDIEENTRPKRSRPTSFAD-E 292
+ SD E ++ +DSE EE ED+ ++ + +R +D E
Sbjct: 75 LNLNASDSESEELHRQKDSDSESEERAEPPASDSENEDVNQHGSDSESEETRKLPGSDSE 134
Query: 293 LAARIKGDAVGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFS 352
+ G A +E+ P+ +++ + +++P+ D E P+++D +
Sbjct: 135 NEELLNGHASDSENEDVGKHPASDSEIEEL------QKSPASDSETEDALKPQISDSESE 188
Query: 353 PFGSGGGLFSGGK-----GLFDDEDEE------SDLFTEAPQDRQAGASVKEE------- 394
S + + D E EE SD +E P QA S EE
Sbjct: 189 EPPRHQASDSENEEPPKPRMSDSESEELPKPQVSDSESEEPPRHQASDSENEELPKPRIS 248
Query: 395 ----------SSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEPQKP-----EQPTPR 439
+S +++P +S + AS +E KP E P+
Sbjct: 249 DSESEDPPRHQASDSENEELPKPRISDSESEDPPRNQASDSENEELPKPRVSDSESEGPQ 308
Query: 440 KSPYGPPPT--------GLFDDDDGD----------DDDDFFSAPHSKPSKTGKVQSTAD 481
K P T DDD D +D F S H K S +
Sbjct: 309 KGPASDSETEDASRHKQKPESDDDSDRENKGEDTEMQNDSFHSDSHMDRKKFHSSDSEEE 368
Query: 482 ------IFGDEEGDLFKEKAVASPEATV--SQTDENKARAEKKVTLSSS----------- 522
+ DE+ +E+ VA +A V DE KA A+K +S +
Sbjct: 369 EHKKQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDEEKASAKKSRVVSDADDSDSDAVSDK 428
Query: 523 -----KNLKPSSETKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLPTLVSLFDDED 577
K + SE + K L + + +DLF S S S + +L+ D+E+
Sbjct: 429 SGKREKTIASDSEEEAGKELSDKKNEEKDLFGSDSESGNEEENLI---ADIFGESGDEEE 485
Query: 578 EEDNLFGGTAAKKQTLCLQAQREEKAKASELSKKKASALLFSSDEEDQWNIPASQTHLAS 637
EE F +++ Q + E + + + + K+ + F SD E S
Sbjct: 486 EEFTGFNQEDLEEEKGETQVKEAEDSDSDD-NIKRGKHMDFLSDFEMMLQRKKSM----- 539
Query: 638 DSRSKGEPRDSGTLQSQ-----EAKAVKKTSLFEEDEE 670
S + RD GT S A VK EED +
Sbjct: 540 -SGKRRRNRDGGTFISDADDVVSAMIVKMNEAAEEDRQ 576
Score = 38.1 bits (87), Expect = 0.057
Identities = 85/377 (22%), Positives = 142/377 (37%), Gaps = 49/377 (12%)
Query: 527 PSSETKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLPTLVSLFDDEDEEDNLFGGT 586
P+S+++T+ L DSE S+ + + AS + P + D E EE
Sbjct: 168 PASDSETEDALKPQISDSE----SEEPPRHQ-ASDSENEEPPKPRMSDSESEE------- 215
Query: 587 AAKKQTLCLQAQREEKAKASELSKKKASALLFS-SDEEDQWNIPASQTH-------LASD 638
K Q +++ + +AS+ ++ S S+ ED AS + SD
Sbjct: 216 LPKPQVSDSESEEPPRHQASDSENEELPKPRISDSESEDPPRHQASDSENEELPKPRISD 275
Query: 639 SRSKGEPRDSGTLQSQEAKAVKKTSLFEEDEEDDLFAIAKDSQKK-TQRVSLLFEDDVDS 697
S S+ PR+ + E + + K + + + E A DS+ + R E D DS
Sbjct: 276 SESEDPPRNQAS--DSENEELPKPRVSDSESEGPQKGPASDSETEDASRHKQKPESDDDS 333
Query: 698 GGSLFGSPPT-------SVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAK 750
G S +KK S+ S+EEE + Q D+K +
Sbjct: 334 DRENKGEDTEMQNDSFHSDSHMDRKKFHSSD------SEEEEHKKQKMDSDEDEKEGEEE 387
Query: 751 ESLKFGRTDVAESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDK 810
+ K +++SE E + V +D S + DK K R KT+ S +EE K
Sbjct: 388 KVAKRKAAVLSDSEDEEKASAKKSRVVSDADDSDSDAVSDKSGK-REKTIASDSEEEAGK 446
Query: 811 -MEDQNIIQAPQKEVGKGRDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTK 869
+ D+ K + D + +EE L + + D + + F G +
Sbjct: 447 ELSDK-----------KNEEKDLFGSDSESGNEEENLIADIFGESGDEEEEEFTGFNQED 495
Query: 870 LLEPSVGSLFGDDEDDD 886
L E + + ED D
Sbjct: 496 LEEEKGETQVKEAEDSD 512
Score = 33.1 bits (74), Expect = 1.8
Identities = 105/517 (20%), Positives = 189/517 (36%), Gaps = 83/517 (16%)
Query: 805 DEEEDKMEDQNIIQAPQKEVGKGRDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAG 864
D E D+ + N + +E+ + +D D+ + EE +N+ DV+
Sbjct: 68 DSENDEPLNLNASDSESEELHRQKDSDS--------ESEERAEPPASDSENE-DVNQHGS 118
Query: 865 TKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEKKRVVKKDHSVDSFKNQKHPESIQG 924
+++ GS D E+++L + S ++ + D ++ QK P S
Sbjct: 119 DSESEETRKLPGS---DSENEELLNGHASDSENEDVGKHPASDSEIEEL--QKSPAS--D 171
Query: 925 SKEKGIWKPETPQDSSGLAPFKTKEPSTRIGKIQANLAINPAALLPTAASQISEVKPVLP 984
S+ + KP+ S P + QA+ + N P + SE P P
Sbjct: 172 SETEDALKPQISDSESEEPP-----------RHQASDSENEEPPKPRMSDSESEELPK-P 219
Query: 985 ELAFPSSEHRRSHGLESVP--VLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQT 1042
+++ SE H LP + + P + S N+ K R
Sbjct: 220 QVSDSESEEPPRHQASDSENEELPKPRISDSESEDPPRHQASDSENEELPKPRISDSESE 279
Query: 1043 RAARRLAAQESSETEDMSVPR-------GPIAQWADGAISPNGHRPQLRAASGEDSTEEA 1095
R A+ SE E++ PR GP A + + + R + + S +DS E
Sbjct: 280 DPPRNQASD--SENEELPKPRVSDSESEGPQKGPASDSETEDASRHKQKPESDDDSDRE- 336
Query: 1096 LAAAAAPWEGGPVPGVDRSPFAKSLGHSRGEADL--FDSGDIFSTGTGSQSVERTKPKAK 1153
G + F HS D F S D S+ E K K
Sbjct: 337 --------NKGEDTEMQNDSF-----HSDSHMDRKKFHSSD-------SEEEEHKKQKMD 376
Query: 1154 IAENPANPPVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFPLLEDED-DLFTDQ 1212
E+ G + K A + S+D+ + AKK+ +D D D +D+
Sbjct: 377 SDEDEKE---GEEEKVAKRKAAVLSDSEDE-----EKASAKKSRVVSDADDSDSDAVSDK 428
Query: 1213 KVKKNETKSNSQQDVI---LTTQDIFEDDIFATEAIKPSQKTREKEKTLESNLF----DD 1265
K+ +T ++ ++ L+ + E D+F +++ ++ +E+ L +++F D+
Sbjct: 429 SGKREKTIASDSEEEAGKELSDKKNEEKDLFGSDS-----ESGNEEENLIADIFGESGDE 483
Query: 1266 NIDIFADLTVKPKEKSKKKVEAKSIFDDDMDDIFSSG 1302
+ F + E+ K + + K D D DD G
Sbjct: 484 EEEEFTGFNQEDLEEEKGETQVKEAEDSDSDDNIKRG 520
>gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens]
Length = 710
Score = 62.0 bits (149), Expect = 4e-09
Identities = 109/492 (22%), Positives = 186/492 (37%), Gaps = 101/492 (20%)
Query: 494 KAVASPEATVSQTDENKARAEKKVTLSSSKN--LKPSSETKTQKGLFSDEEDSEDL---F 548
KA E +VS EK T+SS K LK +S+ K + E+ ++
Sbjct: 203 KATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTV 262
Query: 549 SSQSASKLKGASLLPGKLPTLVSLFDDEDEEDNLFGGTAAKKQTLCLQAQREEK------ 602
SSQ LK S+ + + +++D T + Q L+A R+EK
Sbjct: 263 SSQKPPALKATSVKEDSVLNIA-----REKKDGEKSRTVSFDQPPGLKATRDEKDSLLNI 317
Query: 603 -------AKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQE 655
K +S +K AL +SDE+D ++ + +R K + S + SQ+
Sbjct: 318 ARGKKNGEKTRRVSSRKKPALKATSDEKDSFS---------NITRGKKDGEISRKVSSQK 368
Query: 656 AKAVKKTSLFEEDEEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKK 715
+K TS DEED + IA++++ K
Sbjct: 369 PPTLKGTS----DEEDSVLGIARENKD-----------------------------GEKS 395
Query: 716 KETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAK--ESLKFGRTDVAESEKEGL--LTR 771
+ SE PP L + +EK++ L + K E K S K + EK+ +TR
Sbjct: 396 RTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITR 455
Query: 772 SAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGRDPD 831
++ + S P KGT +VL + E +D + + + + +K G D
Sbjct: 456 EKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTV--SSEKPPGLKATSD 513
Query: 832 AHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLF--- 888
+ + +L + +KD + + KK L S D++D L+
Sbjct: 514 ---------EKDSVLNIARGKKDGE-KTRTVSSRKKPALKATS------DEKDSVLYIAR 557
Query: 889 ---SSAKSQPLVQEK----KRVVKKDHSVDSFKNQKHPESIQGS----KEKGIWKPETPQ 937
KS+ + +K K + K+ SV + +K E I G+ K+ + +
Sbjct: 558 EKKDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKK 617
Query: 938 DSSGLAPFKTKE 949
DS P + K+
Sbjct: 618 DSVSNIPTEIKD 629
Score = 52.8 bits (125), Expect = 2e-06
Identities = 113/525 (21%), Positives = 196/525 (37%), Gaps = 95/525 (18%)
Query: 196 QEDVGLGELSSEEGSVGS--------DRGSIVDTEEEKEEEESDEDFAHHSDNEQNRHTT 247
Q+ L + EEGSV + ++ V ++++ + + ++ S+ + +
Sbjct: 197 QKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDG 256
Query: 248 QMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGD------- 300
++S L A S KE+ + E ++SR SF + D
Sbjct: 257 EISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLN 316
Query: 301 -AVGRVDEEPTTLPSGEAKP--RKTLKEKKERRTPSDDEEDNLFA-------PPKL---T 347
A G+ + E T S KP + T EK + ++D + PP L +
Sbjct: 317 IARGKKNGEKTRRVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTS 376
Query: 348 DEDFSPFGSGGGLFSGGK----------GLFDDEDEESDLFTEAPQDRQAGASVKEESSS 397
DE+ S G G K GL DE+ + A + ++ G K SS
Sbjct: 377 DEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIA-RGKKYGEKTKRVSSR 435
Query: 398 SKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDGD 457
KP + + F T + QKP P G D++D
Sbjct: 436 KKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKP-----------PALKGTSDEEDS- 483
Query: 458 DDDDFFSAPHSKPSKTGKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKV 517
++ +K G+ T + ++ L KA + + +V K EK
Sbjct: 484 ------VLGIARENKDGEKSRT--VSSEKPPGL---KATSDEKDSVLNIARGKKDGEKTR 532
Query: 518 TLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLPTLVSLFDDED 577
T+SS K KP+ + SDE+DS + + K ++ K P L ++ D ED
Sbjct: 533 TVSSRK--KPALKAT------SDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKED 584
Query: 578 EEDNLFGGTAAKKQTLCLQAQREEKAKASELSKKKASALLFSSDEEDQ-WNIPASQTHLA 636
N + +++++ + +S +K AL +SD++D NIP
Sbjct: 585 SVPN-------------MATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIK--- 628
Query: 637 SDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDEEDDLFAIAKDSQ 681
+ + SGT+ SQ+ A K TS+ ++D ++ KD Q
Sbjct: 629 -------DGQQSGTVSSQKQPAWKATSV-KKDSVSNIATEIKDGQ 665
Score = 48.5 bits (114), Expect = 4e-05
Identities = 97/440 (22%), Positives = 168/440 (38%), Gaps = 80/440 (18%)
Query: 361 FSGGKGLFDDEDEESDLFTEAPQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFG 420
F GL DE+ L A + ++ G + SS KP K + F T
Sbjct: 298 FDQPPGLKATRDEKDSLLNIA-RGKKNGEKTRRVSSRKKPALKATSDEKDSFSNITRGKK 356
Query: 421 AASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTA 480
+ QKP P G D++D ++ +K G+ T
Sbjct: 357 DGEISRKVSSQKP-----------PTLKGTSDEEDS-------VLGIARENKDGEKSRT- 397
Query: 481 DIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSD 540
+ ++ L KA + + +V K EK +SS K KPS E SD
Sbjct: 398 -VSSEKPPGL---KASSDEKDSVLNIARGKKYGEKTKRVSSRK--KPSLEAT------SD 445
Query: 541 EEDSEDLFSSQSASKLKGASLLPGKLPTLVSLFDDEDEEDNLFGGTAAKKQTLCLQAQRE 600
E+DS FS+ + K G +L DEED++ G + + +
Sbjct: 446 EKDS---FSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLG----------IARENK 492
Query: 601 EKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVK 660
+ K+ +S +K L +SDE+D + + +R K + + T+ S++ A+K
Sbjct: 493 DGEKSRTVSSEKPPGLKATSDEKDS---------VLNIARGKKDGEKTRTVSSRKKPALK 543
Query: 661 KTSLFEEDEEDDLFAIAKDSQ--KKTQRVSLLF----------EDDVDSGGS------LF 702
TS DE+D + IA++ + +K++ VS ED V + + +
Sbjct: 544 ATS----DEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQIS 599
Query: 703 GSPPTSVPPATK----KKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRT 758
G+ + PA K KK++VS P + ++ + K K+S+ T
Sbjct: 600 GTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIAT 659
Query: 759 DVAESEKEGLLTRSAQETVK 778
++ + + G ++ Q K
Sbjct: 660 EIKDGQIRGTVSPQKQSAQK 679
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 60.8 bits (146), Expect = 8e-09
Identities = 155/743 (20%), Positives = 272/743 (36%), Gaps = 94/743 (12%)
Query: 217 SIVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIE 276
++ T++ E + S+ + H +D + Q D E + ++ A +E +D+ +++
Sbjct: 334 ALKSTKDSLERQRSELEDRHQADIASYQEAIQQLDAELRNTKWEMAAQL-REYQDLLNVK 392
Query: 277 ENTRPKRSRPTSFADELAARIKGDAVGRVDEEPTTLPSG---------------EAKPRK 321
+ + + RI + P +LP G E K +
Sbjct: 393 MALDIEIAAYRKLLEGEECRIGFGPI------PFSLPEGLPKIPSVSTHIKVKSEEKIKV 446
Query: 322 TLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEA 381
K +KE + E+ +E+ G GG+ ++E E + T++
Sbjct: 447 VEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGE---EEEAEGGEEETKS 503
Query: 382 PQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEPQKPEQPTPRKS 441
P +A + KE S K K PA A S + A S +K P+K + P ++
Sbjct: 504 PPAEEAASPEKEAKSPVKEEAKSPAEAKS-----PEKEEAKSPAEVKSPEKAKSPAKEEA 558
Query: 442 PYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGDEEGDL-FKEKAVASPE 500
PP + ++ + S +K + +S A+ E+ KE+A + E
Sbjct: 559 K-SPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAE 617
Query: 501 ATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASKLKGAS 560
A +E K+ AE K S K P+ E E E ++ S +K +
Sbjct: 618 AKSPVKEEAKSPAEVK---SPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEA 674
Query: 561 LLPGKLPTLVSLFDDEDEEDNLFGGTAAKKQTLCLQAQREEKAKASELSKKKASALLFSS 620
P K + V E+ K + +A+ EKAK+ + K+ S
Sbjct: 675 KSPEKAKSPVKAEAKSPEK---------AKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSP 725
Query: 621 DEEDQWNIPASQTHLASDSRSKGE---PRDSGTL--QSQEAKAVKKTSLFEEDEE--DDL 673
+E+ +++ + +++S + P + TL +S EAK K ++ +
Sbjct: 726 VKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKA 785
Query: 674 FAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEK 733
+ K+ K ++ ++D + P +P KK+E S EEEK
Sbjct: 786 KSPVKEEVKSPEKAKSPLKEDAKA-------PEKEIP---KKEEVKSPVK------EEEK 829
Query: 734 EAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHSDLFSSSSPWDKGT 793
++ VK KK E K T E +K+ + ++ + P
Sbjct: 830 PQEVKVKEPPKKAEEEKAP----ATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEP--AVE 883
Query: 794 KPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGRD--PDAHPK-STGVFQDEELLFSHK 850
KP+ V + +E EDK + + P+KE + DA PK T V + E K
Sbjct: 884 KPKESKVEAKKEEAEDKKK----VPTPEKEAPAKVEVKEDAKPKEKTEVAKKEP--DDAK 937
Query: 851 LQKDNDPDVDLFAG-------TKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEKKRV 903
++ + P A +K K E + EDD S S+P K
Sbjct: 938 AKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKP----KAEK 993
Query: 904 VKKDHSVDSFKNQKHPESIQGSK 926
+K S D K+ K PE K
Sbjct: 994 AEKSSSTDQ-KDSKPPEKATEDK 1015
Score = 51.6 bits (122), Expect = 5e-06
Identities = 124/624 (19%), Positives = 221/624 (35%), Gaps = 75/624 (12%)
Query: 196 QEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEED 255
+E + + E S +E + ++ EE EEE E +E ++
Sbjct: 441 EEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKE---------------AKEEEGKE 485
Query: 256 DDGCDLFADSEKEEEDIEDIEENTR-PKRSRPTSFADELAARIKGDAVGRVDEEPTTLPS 314
++G EEE+ E EE T+ P S E + +K +A + E +
Sbjct: 486 EEG--------GEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEA--KSPAEAKSPEK 535
Query: 315 GEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEE 374
EAK +K ++ ++P+ +E +PP+ + S + S K EE
Sbjct: 536 EEAKSPAEVKSPEKAKSPAKEEAK---SPPEAKSPEKEEAKSPAEVKSPEKAK-SPAKEE 591
Query: 375 SDLFTEAPQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEPQKPE 434
+ EA +A + VKEE+ S PA A S + A S +K P+K +
Sbjct: 592 AKSPAEAKSPEKAKSPVKEEAKS-------PAEAKSPVKEE-----AKSPAEVKSPEKAK 639
Query: 435 QPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGDEEGDLFKEK 494
PT ++ P + ++ + S ++ K +S E K K
Sbjct: 640 SPT-KEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKA---EAKSPEKAK 695
Query: 495 AVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSET-KTQKGLFSDEEDSEDLFSSQSA 553
+ EA + ++ + E K + +K ++T + K +E S + S
Sbjct: 696 SPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEK 755
Query: 554 SKLKGASLLPGKLPTLVSLFDDEDEEDNLFGGTAAKKQTLCLQA----QREEKAKASELS 609
+K K P D+ ++ +A + + KA E+
Sbjct: 756 AKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIP 815
Query: 610 KKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDE 669
KK+ +E+ Q A + ++ P+ S++ +A KK + + E
Sbjct: 816 KKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVE 875
Query: 670 EDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVSEAPPLLFSD 729
E A+ K + K + ED PT A K E +A P ++
Sbjct: 876 EKKEPAVEKPKESKVEAKKEEAEDK--------KKVPTPEKEAPAKVEVKEDAKPKEKTE 927
Query: 730 EEEKE---------------AQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQ 774
+KE + + D K E AK+ + +T+ E + L++
Sbjct: 928 VAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPS 987
Query: 775 ETVKHSDLFSSSSPWDKGTKPRTK 798
+ K SSS K +KP K
Sbjct: 988 KP-KAEKAEKSSSTDQKDSKPPEK 1010
Score = 42.4 bits (98), Expect = 0.003
Identities = 102/456 (22%), Positives = 163/456 (35%), Gaps = 48/456 (10%)
Query: 891 AKSQPLVQE-KKRVVKKDHSVDSFKNQKHP---ESIQGSKEKGIWKPETPQDSSGLAPFK 946
AKS P + +K K V S + K P E+ ++ K K ++P +P +
Sbjct: 558 AKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAE 617
Query: 947 TKEPSTRIGKIQANLAINPAALLPTAASQISEVKPVLPELAFPSSEHRRSHGLESVPVLP 1006
K P K A + A PT S K PE S + +++ P
Sbjct: 618 AKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSP 677
Query: 1007 GSGEAGVSFDLPAQADTLHSANKSRVKMRGK-----RRPQTRAARRLAAQESSETEDMSV 1061
++ V A+A + A KS VK K + P A+ +S E+
Sbjct: 678 EKAKSPVK----AEAKSPEKA-KSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKT 732
Query: 1062 PRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAA--AAPWEGGPVPGVDRSPFAKS 1119
P + + A SP + +A + + + EA A A P +SP +
Sbjct: 733 PEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEE 792
Query: 1120 LGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANPPV---GGKAKSPMFPALG 1176
+ S +A D + E K K E P V KA+ PA
Sbjct: 793 V-KSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATP 851
Query: 1177 EASSDDDLFQSAKPKPAKKTNPFPLLEDEDDLFTDQ-KVKKNETKSNSQQD--VILTTQD 1233
+ D S K + KK P P +E++ + ++ K K E K +D + T +
Sbjct: 852 KTEEKKD---SKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEK 908
Query: 1234 IFEDDIFATEAIKPSQKT------------REKEKTLE-SNLFDDNIDIFADLTVKPKEK 1280
+ E KP +KT +E K E + D + KP+EK
Sbjct: 909 EAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEK 968
Query: 1281 SKKKVEAKSIFDDDMDDIFSSGIQAKTTKPKSRSAQ 1316
K + +AK +DD + + +KPK+ A+
Sbjct: 969 PKTEAKAK---EDD------KTLSKEPSKPKAEKAE 995
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 59.3 bits (142), Expect = 2e-08
Identities = 97/589 (16%), Positives = 194/589 (32%), Gaps = 31/589 (5%)
Query: 205 SSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFAD 264
SS+ S S+ S D+ + + SD D + S++ + ++ SD + D D +D
Sbjct: 566 SSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSD 625
Query: 265 SEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRKTLK 324
S K E D D + + S + +D + ++ D ++ S +
Sbjct: 626 SSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSS-----S 680
Query: 325 EKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDE----DEESDLFTE 380
+ S D D+ + D S S S D + + SD
Sbjct: 681 SDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNS 740
Query: 381 APQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEPQKPEQPTPRK 440
+ + +S +SS S + S D+ + S S +
Sbjct: 741 SDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSS-DSSNSSDSNDSSNSSDSSDSSN 799
Query: 441 SPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTADI--FGDEEGDLFKEKAVAS 498
S + D D D D S+ S S + +++D D + + S
Sbjct: 800 SSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRS 859
Query: 499 PEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASKLKG 558
+ S + ++ + + SS + + S+ + + S + DS D +S +S
Sbjct: 860 DSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSN 919
Query: 559 ASLLPGKLPTLVSLFDDEDEEDNLFGGTAAKKQTLCLQAQREEKAKASELSKKKASALLF 618
+S D + ++ ++ + + + +S+ S S+
Sbjct: 920 SS-------------DSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSS--N 964
Query: 619 SSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDEEDDLFAIAK 678
SSD D + +S + +SDS + DS S + + + + + D +
Sbjct: 965 SSDSSDSNSSDSSDSSNSSDSSDSSDSSDS----SDSSDSSNSSDSSDSSDSSDSSNSSD 1020
Query: 679 DSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLG 738
S S D DS S S + ++ ++ + SD +
Sbjct: 1021 SSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1080
Query: 739 VKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHSDLFSSSS 787
+S+ S +D ++S + S+ + + SS S
Sbjct: 1081 SSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDS 1129
Score = 50.4 bits (119), Expect = 1e-05
Identities = 105/647 (16%), Positives = 208/647 (32%), Gaps = 58/647 (8%)
Query: 157 NSDSEEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRG 216
NSD +D+ NG SK + + + ++ + + + G
Sbjct: 494 NSDESKDNGNGS--------------------DSKGAEDDDSDSTSDTNNSDSNGNGNNG 533
Query: 217 SIVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIE 276
+ + + + + +SD + SD+ + ++ SD + D +DS+ + D D
Sbjct: 534 NDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSS--SDSDSSDSDSSDSS 591
Query: 277 ENTRPKRSRPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDE 336
++ S + +D + D+ D + + S E+ + + + S D
Sbjct: 592 DSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKS-ESDSSDSDSKSDSSDSNSSDS 650
Query: 337 EDNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEAPQDRQAGASVKEESS 396
DN + + S S S D SD + + +S +SS
Sbjct: 651 SDNSDSSDSSNSSNSS--DSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSS 708
Query: 397 SSKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDG 456
S + + D+ +S S + S D
Sbjct: 709 DSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSS 768
Query: 457 DDDDDFFSAPHSKPSKTGKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKK 516
D D S+ S S + +++D + +S + S +D + +
Sbjct: 769 DSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNS----- 823
Query: 517 VTLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLPTLVSLFDDE 576
S S N SS++ SD DS D S S+++ + + D
Sbjct: 824 ---SDSSNSSDSSDSSNSSD-SSDSSDSSDGSDSDSSNRSDSS-----------NSSDSS 868
Query: 577 DEEDNLFGGTAAKKQTLCLQAQREEKAKASELSKKKASALLFSSDEEDQWNIP------- 629
D D+ ++ + + + +S S +S SSD D N
Sbjct: 869 DSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSN 928
Query: 630 ASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDEEDDLFAIAKDSQKKTQRV-- 687
+S +SDS + + DS + + S D D + + DS +
Sbjct: 929 SSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDS 988
Query: 688 --SLLFEDDVDSGGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKK 745
S D DS S S + ++ ++ + + SD +
Sbjct: 989 SDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDS 1048
Query: 746 VESAKESLKFGRTDVAES--EKEGLLTRSAQETVKHSDLFSSSSPWD 790
+S+ S +D ++S + + + ++ + SD SS+ D
Sbjct: 1049 SDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSD 1095
Score = 49.3 bits (116), Expect = 2e-05
Identities = 132/791 (16%), Positives = 257/791 (32%), Gaps = 75/791 (9%)
Query: 195 EQEDVGLGELSSEEGSVGSDRGSIVDTEEEKE---EEESDEDFAHHSDNEQNRHTTQMSD 251
E ED G G+ EE G D + +E ++ E++ D +SD+++ D
Sbjct: 253 EDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSDSKEYYDPEGKED 312
Query: 252 EEEDDDGCDLFADSEK------EEEDIEDIEENTRPKRSRPTSFADELAARIKGDAVGRV 305
+ DG D + SE+ E+ + IE+ + + + + AVG+
Sbjct: 313 PHNEVDG-DKTSKSEENSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKESETHAVGKS 371
Query: 306 DEEPTTLPSGEAKPRKTLKEKKERRTPSDD-----------------EEDNLFAPPKLTD 348
++ + + R KE + +D E N+ P + ++
Sbjct: 372 QDKGIEIKGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGEVVNIEGPGQKSE 431
Query: 349 EDFSPFGSGGGLFSGGKGL----FDDEDEESDLFTEAPQDR-QAGASVKEESSSSKPGKK 403
S G S G FDD+ + D + + A+ + +++SS G
Sbjct: 432 PGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDA 491
Query: 404 IPAGAVSVFLGDTDVFGAASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDD--------- 454
S G+ G+ S + + T G G D+D
Sbjct: 492 SYNSDESKDNGN----GSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKS 547
Query: 455 -----DGDDDDDFFSAPHSKPSKTGKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDEN 509
D D + + S S + S++D + + +S + S + ++
Sbjct: 548 DSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDS 607
Query: 510 KARAEKKVTLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLPTL 569
++ + SS + SS++++ + DS D SS S+ +
Sbjct: 608 SDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSS---- 663
Query: 570 VSLFDDEDEEDNLFGGTAAKKQTLCLQAQREEKAKASELSKKKASALLFSSDEEDQWNIP 629
+ D D D+ +++ + + + +SE S S+ SSD D N
Sbjct: 664 -NSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSN 722
Query: 630 ASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDEEDDLFAIAKDSQKKTQRVSL 689
+S + ++ S S S + S ++ +S + + + DS + S
Sbjct: 723 SSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSD--SS 780
Query: 690 LFEDDVDSGGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESA 749
D DS S S ++ ++ ++ + SD + + S D +S+
Sbjct: 781 NSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDS---SDSDSSNSSDSSNSSDSS-DSS 836
Query: 750 KESLKFGRTDVAESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEED 809
S +D ++ S ++ SD +SS D + D +
Sbjct: 837 NSSDSSDSSDSSDG--------SDSDSSNRSDSSNSSDSSDSSDSSNSS------DSSDS 882
Query: 810 KMEDQNIIQAPQKEVGKGRDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTK 869
+++ + + D D+ S + S + N D + + +
Sbjct: 883 SDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSS 942
Query: 870 LLEPSVGSLFGDDEDDDLFSSAKSQPLVQEKKRVVKKDHSVDSFKNQKHPESIQGSKEKG 929
S S D + SS S +S DS + +S S
Sbjct: 943 DSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSN 1002
Query: 930 IWKPETPQDSS 940
DSS
Sbjct: 1003 SSDSSDSSDSS 1013
Score = 39.7 bits (91), Expect = 0.020
Identities = 59/351 (16%), Positives = 120/351 (34%), Gaps = 16/351 (4%)
Query: 205 SSEEGSVGSDRGSIVDTEEEKEEEES-DEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFA 263
+S + S SD + D+ + S D ++ SD+ + +++ SD + D D +
Sbjct: 940 NSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDS-S 998
Query: 264 DSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRKTL 323
DS + + + + S ++ +D + D+ D ++ S ++
Sbjct: 999 DSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSS-DSSDSSDSSNS 1057
Query: 324 KEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEAPQ 383
+ + SD + + + + E S S D + SD +
Sbjct: 1058 SDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1117
Query: 384 DRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEPQKPEQPTPRKSPY 443
+ +S +SS S + S ++ +S S + S
Sbjct: 1118 SDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDS 1177
Query: 444 GPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGDEEGDLFKEKAVASPEATV 503
+ D D D S+ S S + ++D + + + +S +
Sbjct: 1178 S-------NSSDSSDSSD--SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1228
Query: 504 SQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSAS 554
S ++E+ ++ + S S N SS++ SD D D SQS S
Sbjct: 1229 SDSNESSDSSDSSDS-SDSSNSSDSSDSSDSSDSTSDSNDESD---SQSKS 1275
Score = 35.8 bits (81), Expect = 0.28
Identities = 54/343 (15%), Positives = 104/343 (30%), Gaps = 28/343 (8%)
Query: 206 SEEGSVGSDRGSIVDTEEEKEEEESDE--DFAHHSDNEQNRHTTQMSDEEEDDDGCDLFA 263
S + S SD D+ + +S + D ++ SD+ + ++ SD + D D
Sbjct: 985 SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSD--- 1041
Query: 264 DSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRKTL 323
+ D D +++ S +S + + + E + S +
Sbjct: 1042 --SSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDS 1099
Query: 324 KEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEAPQ 383
+ + SD + + + + + S S D E SD +
Sbjct: 1100 SDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDS 1159
Query: 384 DRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEPQKPEQPTPRKSPY 443
+ +S +SS S + S D+ +S S
Sbjct: 1160 SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS-------- 1211
Query: 444 GPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGDEEGDLFKEKAVASPEATV 503
D D D D + S S S + D + S ++T
Sbjct: 1212 --------DSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTS 1263
Query: 504 SQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSDEEDSED 546
DE+ ++++ S + N S +G S+ S+D
Sbjct: 1264 DSNDESDSQSK-----SGNGNNNGSDSDSDSEGSDSNHSTSDD 1301
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 59.3 bits (142), Expect = 2e-08
Identities = 112/521 (21%), Positives = 193/521 (37%), Gaps = 96/521 (18%)
Query: 95 IENRVYDEEVEEPVLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIK 154
I +++ +VE P LK + K +E E K D +++EA+ + L + ++ +
Sbjct: 432 ISSKIQKPKVEAPKLKVQ-HKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKE 490
Query: 155 AGNSDSEEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSD 214
A EE +A E+ + + P E+ EEG
Sbjct: 491 AAEEKEEEPEAEEE-EVAAKKSPVKATAP-------------------EVKEEEGEK--- 527
Query: 215 RGSIVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFADSEKEEEDIED 274
+ EE +EEEE +++ A E+ + S E+E+ + + ++E E E+ E
Sbjct: 528 -----EEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEA 582
Query: 275 IEENTRPKRSRPTSFADELAARIKGD----AVGRVDEEPTTLPSGEAKPRKTLKEKKERR 330
EE ++S + +EL A K + A V + P P+ ++EK +
Sbjct: 583 KEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSP 642
Query: 331 TPSDDEEDNLFAP-PKLTDED--------------------FSPFGSGGGLFSGGKGLFD 369
P E+ +P PK E+ SP GKG +
Sbjct: 643 VPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKG--E 700
Query: 370 DEDEESDLFTEAPQDRQAGASVKEESSSSKPGKK-----IPAGAVSVFLGDTDVFGAASV 424
++EE EAP++ + KEE P KK + AV+ + T
Sbjct: 701 QKEEEEKEVKEAPKEEK--VEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLE 758
Query: 425 PSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFG 484
KE KP Q K G + G +++ S +K S+ + ++ G
Sbjct: 759 KETKEEGKPLQQEKEKEKAG--------GEGGSEEEG--SDKGAKGSRKEDIAVNGEVEG 808
Query: 485 DEE---------GDLFKEKAVASPEATVSQTDENKA--RAEKKVTLSSSKNLKPS----- 528
EE +EK V + +S DE K ++E+KV ++ + S
Sbjct: 809 KEEVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKITSEGGDG 868
Query: 529 -------SETKTQKGLFSDEEDSEDLFSSQSASKLKGASLL 562
S T TQK +E E L S++ K+ +++
Sbjct: 869 ATKYITKSVTVTQKVEEHEETFEEKLVSTKKVEKVTSHAIV 909
Score = 39.7 bits (91), Expect = 0.020
Identities = 148/779 (18%), Positives = 279/779 (35%), Gaps = 111/779 (14%)
Query: 100 YDEEVEEPVLKAEAEKTEQEKTREQKEVDLIP--------------KVQEAVNYGLQVLD 145
YD+E+ E L+A E EK + Q + D + ++++ ++ L
Sbjct: 150 YDQEIRE--LRATLEMVNHEKAQVQLDSDHLEEDIHRLKERFEEEARLRDDTEAAIRALR 207
Query: 146 SAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELS 205
E+ + D + V + + + L + S + +E++D ++S
Sbjct: 208 KDIEEASLVKVELDKKVQSLQDEVAFLRSNHEEEVADLLAQIQASHITVERKDYLKTDIS 267
Query: 206 SEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDN-EQNRHTTQMSDEEEDDDGCDLFAD 264
+ + S S D + EE +A ++ EQN+ + + EE + L +
Sbjct: 268 TALKEIRSQLESHSDQNMHQAEEWFKCRYAKLTEAAEQNKEAIRSAKEEIAEYRRQLQSK 327
Query: 265 S----------EKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDAVGRVDEEPTTLPS 314
S E E + DIEE S +L ++G
Sbjct: 328 SIELESVRGTKESLERQLSDIEERHNHDLSSYQDTIQQLENELRGT-------------- 373
Query: 315 GEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEE 374
+ + + L+E ++ + + A KL + + + F + G +G
Sbjct: 374 -KWEMARHLREYQDLLNVKMALDIEIAAYRKLLEGEETRFSTFAGSITGPLYTHRPPITI 432
Query: 375 SDLF----TEAPQDRQAGASVKE-------ESSSSKPGKKIPAGAVSVFLGDTDVFGAAS 423
S EAP+ + V+E E S+ + + A + + + A+
Sbjct: 433 SSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAA 492
Query: 424 VPSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTADIF 483
+EP+ E+ K +++G+ +++ + + K +
Sbjct: 493 EEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGG 552
Query: 484 GDEEGDLFKEKAVASPEATVSQTD--ENKARAEKKVTLSSSKNLKPSSETKTQKGLFSDE 541
++EG KE+ T ++ + E +A+ EKKV + S E T++ L +D
Sbjct: 553 SEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVE-------EKSEEVATKEELVADA 605
Query: 542 --EDSEDLFSSQSASKLKGASLLPGKLPTLVSLFDDEDEEDNLFGGTAAKKQTLCLQAQR 599
E E S S ++ GK P S +++ + K ++ ++
Sbjct: 606 KVEKPEKAKSPVPKSPVEEK----GKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPV 661
Query: 600 EEKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRS--KGEPRDSGTLQSQEAK 657
EEK K S +SK +E+ + +P S A KGE ++ + +E K
Sbjct: 662 EEKGK-SPVSKSPV-------EEKAKSPVPKSPVEEAKSKAEVGKGEQKEE---EEKEVK 710
Query: 658 AVKKTSLFEEDEEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKE 717
K E+ EE KD +K + S + E+ V ++ S + +KE
Sbjct: 711 EAPKEEKVEKKEEKP-----KDVPEKKKAESPVKEEAVAEVVTITKSVKVHL-----EKE 760
Query: 718 TVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLK---------FGRTDVAESEKEGL 768
T E PL E+EK G + + AK S K G+ +V + KE
Sbjct: 761 TKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKG 820
Query: 769 LTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKG 827
R ++ V + L S + KG D+ E+K+ ++ E G G
Sbjct: 821 SGREEEKGVVTNGLDLSPADEKKGG-----------DKSEEKVVVTKTVEKITSEGGDG 868
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 59.3 bits (142), Expect = 2e-08
Identities = 112/521 (21%), Positives = 193/521 (37%), Gaps = 96/521 (18%)
Query: 95 IENRVYDEEVEEPVLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIK 154
I +++ +VE P LK + K +E E K D +++EA+ + L + ++ +
Sbjct: 56 ISSKIQKPKVEAPKLKVQ-HKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKE 114
Query: 155 AGNSDSEEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSD 214
A EE +A E+ + + P E+ EEG
Sbjct: 115 AAEEKEEEPEAEEE-EVAAKKSPVKATAP-------------------EVKEEEGEK--- 151
Query: 215 RGSIVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFADSEKEEEDIED 274
+ EE +EEEE +++ A E+ + S E+E+ + + ++E E E+ E
Sbjct: 152 -----EEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEA 206
Query: 275 IEENTRPKRSRPTSFADELAARIKGD----AVGRVDEEPTTLPSGEAKPRKTLKEKKERR 330
EE ++S + +EL A K + A V + P P+ ++EK +
Sbjct: 207 KEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSP 266
Query: 331 TPSDDEEDNLFAP-PKLTDED--------------------FSPFGSGGGLFSGGKGLFD 369
P E+ +P PK E+ SP GKG +
Sbjct: 267 VPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKG--E 324
Query: 370 DEDEESDLFTEAPQDRQAGASVKEESSSSKPGKK-----IPAGAVSVFLGDTDVFGAASV 424
++EE EAP++ + KEE P KK + AV+ + T
Sbjct: 325 QKEEEEKEVKEAPKEEK--VEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLE 382
Query: 425 PSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFG 484
KE KP Q K G + G +++ S +K S+ + ++ G
Sbjct: 383 KETKEEGKPLQQEKEKEKAG--------GEGGSEEEG--SDKGAKGSRKEDIAVNGEVEG 432
Query: 485 DEE---------GDLFKEKAVASPEATVSQTDENKA--RAEKKVTLSSSKNLKPS----- 528
EE +EK V + +S DE K ++E+KV ++ + S
Sbjct: 433 KEEVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKITSEGGDG 492
Query: 529 -------SETKTQKGLFSDEEDSEDLFSSQSASKLKGASLL 562
S T TQK +E E L S++ K+ +++
Sbjct: 493 ATKYITKSVTVTQKVEEHEETFEEKLVSTKKVEKVTSHAIV 533
Score = 38.9 bits (89), Expect = 0.034
Identities = 88/415 (21%), Positives = 156/415 (37%), Gaps = 58/415 (13%)
Query: 428 KEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGDEE 487
+EP+ E+ K +++G+ +++ + + K + ++E
Sbjct: 121 EEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKE 180
Query: 488 GDLFKEKAVASPEATVSQTD--ENKARAEKKVTLSSSKNLKPSSETKTQKGLFSDE--ED 543
G KE+ T ++ + E +A+ EKKV + S E T++ L +D E
Sbjct: 181 GSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVE-------EKSEEVATKEELVADAKVEK 233
Query: 544 SEDLFSSQSASKLKGASLLPGKLPTLVSLFDDEDEEDNLFGGTAAKKQTLCLQAQREEKA 603
E S S ++ GK P S +++ + K ++ ++ EEK
Sbjct: 234 PEKAKSPVPKSPVEEK----GKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKG 289
Query: 604 KASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRS--KGEPRDSGTLQSQEAKAVKK 661
K S +SK +E+ + +P S A KGE ++ + +E K K
Sbjct: 290 K-SPVSKSPV-------EEKAKSPVPKSPVEEAKSKAEVGKGEQKEE---EEKEVKEAPK 338
Query: 662 TSLFEEDEEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVSE 721
E+ EE KD +K + S + E+ V ++ S + +KET E
Sbjct: 339 EEKVEKKEEKP-----KDVPEKKKAESPVKEEAVAEVVTITKSVKVHL-----EKETKEE 388
Query: 722 APPLLFSDEEEKEAQLGVKSVDKKVESAKESLK---------FGRTDVAESEKEGLLTRS 772
PL E+EK G + + AK S K G+ +V + KE R
Sbjct: 389 GKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGRE 448
Query: 773 AQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKG 827
++ V + L S + KG D+ E+K+ ++ E G G
Sbjct: 449 EEKGVVTNGLDLSPADEKKGG-----------DKSEEKVVVTKTVEKITSEGGDG 492
>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
precursor [Homo sapiens]
Length = 513
Score = 57.4 bits (137), Expect = 9e-08
Identities = 106/480 (22%), Positives = 180/480 (37%), Gaps = 67/480 (13%)
Query: 213 SDRGSIVDTEEEKEEEESDEDFAHH---SDNEQ---------NRHTTQMSDE---EEDDD 257
S GS V +EE+ E+ SD + SD+ Q +R T + D+ +EDD
Sbjct: 50 SSEGSKVSSEEQANEDPSDSTQSEEGLGSDDHQYIYRLAGGFSRSTGKGGDDKDDDEDDS 109
Query: 258 GCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDAVGRVDEEPTTLPSGEA 317
G D F D + +D +E + D + A + G+ + TT S E
Sbjct: 110 GDDTFGDDDSGPGP-KDRQEGGNSRLGSDEDSDDTIQASEESAPQGQDSAQDTTSESREL 168
Query: 318 KPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDL 377
+ K E + + E ++E + GS G G DDE +SD
Sbjct: 169 DNEDRVDSKPEGGDSTQESE---------SEEHWVGGGSDGESSHGDGSELDDEGMQSD- 218
Query: 378 FTEAPQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEPQKPEQPT 437
D ++ S + S + G K + +T G + + + P +
Sbjct: 219 ------DPESIRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQL-----LEHPSRKI 267
Query: 438 PRKSPYG-PPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGDEEGD----LFK 492
RKS DD++ ++ S +S TG Q D GD + D L +
Sbjct: 268 FRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQ 327
Query: 493 EK--------AVASPEATVSQTDENKARAEKKVTLSSSKNLKP-SSETKTQKGLFSDEED 543
E+ + +S EA +S + + E+ V+ S N P +S + Q+ S EED
Sbjct: 328 EESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEED 387
Query: 544 SEDLFS-SQSASKLKGASLLPGKLPTLVSLFDDEDEEDNLFGGTAAKKQTLCLQAQREEK 602
S S S+S S+ + A + + E++N + + ++Q EE
Sbjct: 388 SSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEES 447
Query: 603 AKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKT 662
+ S + S S +ED ++ + SK + G L++ E ++ K T
Sbjct: 448 HSEEDDSDSQDS----SRSKED-----------SNSTESKSSSEEDGQLKNIEIESRKLT 492
Score = 38.1 bits (87), Expect = 0.057
Identities = 90/406 (22%), Positives = 147/406 (36%), Gaps = 78/406 (19%)
Query: 452 DDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGDEE--GDLFKEKAVASPEATVSQTDEN 509
DDD+ D DD F S P + + G +E D + ++P+ S D
Sbjct: 103 DDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDEDSDDTIQASEESAPQGQDSAQD-- 160
Query: 510 KARAEKKVTLSSSKNL--KPSSETKTQKGLFSDEEDSEDLF---SSQSASKLKGASLLPG 564
T S S+ L + ++K + G + E +SE+ + S S S L
Sbjct: 161 --------TTSESRELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGSELDD 212
Query: 565 KLPTLVSLFDDEDEEDNLFGGTAAKKQTLCLQAQREEKAKASELSKKKASALLFS----- 619
+ + D+ E G + + E ++ + S LL
Sbjct: 213 E-----GMQSDDPESIRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKI 267
Query: 620 ------SDEEDQWNIPASQT--HLASDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDEED 671
S+E+D+ + + T + SDS RD+G SQ + K S +ED ++
Sbjct: 268 FRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGL--SQPRRDSKGDS--QEDSKE 323
Query: 672 DLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVSEA------PPL 725
+L SQ+++Q V D S S + + + ++E VSE+ P
Sbjct: 324 NL------SQEESQNV-----DGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTT 372
Query: 726 LF--------SDEEEKEAQLGVKSVDKKVESA----KESLKFGR------TDVAESEKEG 767
+ S EE+ L + + E A ESL F D S +EG
Sbjct: 373 SYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEG 432
Query: 768 LLTRS----AQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEED 809
L + S +Q HS+ S S +K + + S EED
Sbjct: 433 LQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEED 478
Score = 34.7 bits (78), Expect = 0.63
Identities = 42/186 (22%), Positives = 81/186 (43%), Gaps = 26/186 (13%)
Query: 157 NSDSEEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRG 216
N S+E+ + + E++ E + D P P + +QED SSEE S +
Sbjct: 345 NLSSQENSSESQEEVVSESRG---DNPDPT---TSYVEDQEDSD----SSEEDSSHTLSH 394
Query: 217 SIVDTEEEKEEEESDE--DFAHHS-DNEQNRHTTQMSDEEEDDDGCDLFADSEKEEEDIE 273
S ++ EE+ + ES E +F+ S ++ ++ +++ + + ++ EED
Sbjct: 395 SKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDS 454
Query: 274 DIEENTRPKRSRPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRKTLKEKKERRTPS 333
D ++++R K D + K + EE L + E + RK + + P
Sbjct: 455 DSQDSSRSKE-------DSNSTESKSSS-----EEDGQLKNIEIESRKLTVDAYHNK-PI 501
Query: 334 DDEEDN 339
D++DN
Sbjct: 502 GDQDDN 507
Score = 32.0 bits (71), Expect = 4.1
Identities = 93/463 (20%), Positives = 166/463 (35%), Gaps = 72/463 (15%)
Query: 486 EEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSDEED-S 544
E+ + +K +P + ++ ++ KV+ N PS T++++GL SD+
Sbjct: 28 EDSEEWKGHLAQAPTPPLESSESSEG---SKVSSEEQANEDPSDSTQSEEGLGSDDHQYI 84
Query: 545 EDLFSSQSASKLKGASLLPGKLPTLVSLFDDEDEEDNLFGGTAAKKQTLCLQAQREEKAK 604
L S S KG D +D+ED+ T + R+E
Sbjct: 85 YRLAGGFSRSTGKGGD-------------DKDDDEDDSGDDTFGDDDSGPGPKDRQEGGN 131
Query: 605 ASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTSL 664
+ S + + + +S+E + P Q A D+ S E R+ ++K S
Sbjct: 132 SRLGSDEDSDDTIQASEE----SAPQGQDS-AQDTTS--ESRELDNEDRVDSKPEGGDST 184
Query: 665 FEEDEEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVSEAPP 724
E + E+ D + S L ++ + S P S+ S
Sbjct: 185 QESESEEHWVGGGSDGESSHGDGSELDDEGMQS------DDPESIRSERGNSRMNSAGMK 238
Query: 725 LLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVA-ESEKEGLLTRSAQETVKHSDLF 783
S E ++A + +E + F ++ ++ E ++ L + E VK SD
Sbjct: 239 SKESGENSEQANTQDSGGSQLLEHPSRKI-FRKSRISEEDDRSELDDNNTMEEVK-SDST 296
Query: 784 SSSSPWDKG-TKPRTKTVLSLFDEEED-----KMEDQNIIQAPQKEVGKGRDPDAHPKST 837
+S+ D G ++PR S D +ED E+ + P E + + + S+
Sbjct: 297 ENSNSRDTGLSQPRRD---SKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSS 353
Query: 838 GVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLV 897
+ +E + S + DP S D ED D S L
Sbjct: 354 ---ESQEEVVSESRGDNPDPTT-----------------SYVEDQEDSDSSEEDSSHTLS 393
Query: 898 QEKKRVVKKDHSVDSFKNQKHPESIQGSKEKGIWKPETPQDSS 940
K ++ DS + ES+ S+E PE+P+D +
Sbjct: 394 HSKSE--SREEQADS----ESSESLNFSEE----SPESPEDEN 426
>gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH
polyclonal antibodies [Homo sapiens]
Length = 1430
Score = 57.4 bits (137), Expect = 9e-08
Identities = 156/750 (20%), Positives = 271/750 (36%), Gaps = 129/750 (17%)
Query: 105 EEPVLKAEAEK------TEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNS 158
++P LK ++K T E EQK ++P V++ +N L D+ + +
Sbjct: 24 KQPALKDTSDKNDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTEDEFAL 83
Query: 159 DSE----------EDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEE 208
+SE + + +E +L P + +DR L YL+ +D E +
Sbjct: 84 ESEIISKLYIPKRKIISPRSIEDVLPPVEEAVDRCL-YLLDRFAQAVTKDKFALESENIS 142
Query: 209 GSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFADSEKE 268
++R +I EK + D + + T D+ D +G L A +K
Sbjct: 143 EPYFTNRRTISQQSAEKLDAACGID--------KTENGTLFEDQNVDKEGKALPATGQKA 194
Query: 269 EEDIEDIEENTRPKRSRPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRKTLKEKKE 328
++ P + +D ++ R +G +D ++ S E P TL K+
Sbjct: 195 -----NVSPEQPPLFTHTVKDSDHISTRF----LGSMDSLTSSEESSERPPLSTLTLKEA 245
Query: 329 RRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEAPQDRQAG 388
+ PP P K DD+D S++ TE + +G
Sbjct: 246 DPSSKAAMRRKDSPPPGKVSSQKQP---------AEKATSDDKDSVSNIATEIKEGPISG 296
Query: 389 ASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEPQKPEQPTPRKSPYGPPPT 448
SS +P +K + D + +KE Q+ +P+K
Sbjct: 297 TV----SSQKQPAEKATS--------DEKDSVSNIATEIKEGQQSGTVSPQKQ------- 337
Query: 449 GLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDE 508
+ K + +T G + G + +K S +AT +TD
Sbjct: 338 ------------SAWKVIFKKKVSLLNI-ATRITGGGKSGTVSSQKQPPS-KATSDKTDS 383
Query: 509 --NKARAEKKV----TLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASKLKGASLL 562
N A K T+SS K +P+ + T DEEDS +++ K ++
Sbjct: 384 ALNIATEIKDGLQCGTVSSQK--QPALKATT------DEEDSVSNIATEIKDGEKSGTVS 435
Query: 563 PGKLPTLVSLFDDEDEEDNLFGGTAAKKQTLCLQAQREEKAKASELSKKKASALLFSSDE 622
K P L + D+ED L + + ++ K+ +S +K AL ++DE
Sbjct: 436 SQKQPALKATTDEED-------------SVLNIATEIKDGEKSETVSSQKQPALKATTDE 482
Query: 623 EDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDEEDDLFAIAKDSQK 682
ED +I A++ + SGT+ S++ A+K TS DE+D I + +K
Sbjct: 483 EDSVSIIATEIK---------DGEKSGTVSSRKKPALKATS----DEKDSFSNITR--EK 527
Query: 683 KTQRVSLLFEDDVDSGGSLFGSPPTSV-------PPATKKKETVSEAPPLLFSDEEEKEA 735
K +S SV K + SE PP L + +EK++
Sbjct: 528 KDGEISRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLKATRDEKDS 587
Query: 736 QLGVKSVDKKVESAKESLKFGRTDV-AESEKEGLLTRSAQETVKH---SDLFSSSSPWDK 791
L + K E + + + A S+KE + A ET + S P K
Sbjct: 588 LLNIARGKKYGEKTRRVSSHKQPALKATSDKENSVPNMATETKDEQISGTVSSQKQPALK 647
Query: 792 GTKPRTKTVLSLFDEEEDKMEDQNIIQAPQ 821
T + +V ++ E +D + + Q
Sbjct: 648 ATSDKKDSVSNIPTEIKDGQQSGTVSSQKQ 677
Score = 49.3 bits (116), Expect = 2e-05
Identities = 113/551 (20%), Positives = 204/551 (37%), Gaps = 90/551 (16%)
Query: 384 DRQAGASVKEESSSSKPGKKIPAGAVSVFLG------------DTDVFGAASVPSMKEPQ 431
D+ ++ E+ + K GK +PA + D+D + SM
Sbjct: 167 DKTENGTLFEDQNVDKEGKALPATGQKANVSPEQPPLFTHTVKDSDHISTRFLGSMDSLT 226
Query: 432 KPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGDEEGDLF 491
E+ + R P T + D P K + A+ ++ D
Sbjct: 227 SSEESSERP----PLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSV 282
Query: 492 KEKAVASPEATVSQTDENKARAEKKVTLS---SSKNLKPSSETKTQKGLFSDEEDSE-DL 547
A E +S T ++ + +K T S N+ + Q G S ++ S +
Sbjct: 283 SNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAWKV 342
Query: 548 FSSQSASKLKGASLLPG--KLPTLVSLFDDEDEEDNLFGGTAAKKQT-LCLQAQREEKAK 604
+ S L A+ + G K T+ S + T+ K + L + + ++ +
Sbjct: 343 IFKKKVSLLNIATRITGGGKSGTVSSQKQPPSK------ATSDKTDSALNIATEIKDGLQ 396
Query: 605 ASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTSL 664
+S +K AL ++DEED S +++A++ + GE SGT+ SQ+ A+K T+
Sbjct: 397 CGTVSSQKQPALKATTDEED------SVSNIATEIKD-GEK--SGTVSSQKQPALKATT- 446
Query: 665 FEEDEEDDLFAIAKDSQ--KKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVSEA 722
DEED + IA + + +K++ VS + PA K ++
Sbjct: 447 ---DEEDSVLNIATEIKDGEKSETVS------------------SQKQPALKATTDEEDS 485
Query: 723 PPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHSDL 782
++ ++ ++ E V S K A K +++ +K+G ++R+
Sbjct: 486 VSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVS-------- 537
Query: 783 FSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGRDPD------AHPKS 836
S P K T +VLS+ EE+D + + + + RD A K
Sbjct: 538 -SQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLKATRDEKDSLLNIARGKK 596
Query: 837 TGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPL 896
G + + SHK K T E SV ++ + +D+ + + SQ
Sbjct: 597 YG--EKTRRVSSHKQ-----------PALKATSDKENSVPNMATETKDEQISGTVSSQKQ 643
Query: 897 VQEKKRVVKKD 907
K KKD
Sbjct: 644 PALKATSDKKD 654
Score = 38.1 bits (87), Expect = 0.057
Identities = 107/566 (18%), Positives = 205/566 (36%), Gaps = 76/566 (13%)
Query: 263 ADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRKT 322
A S+K + + E + S + A + D V T + GE +
Sbjct: 376 ATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVS 435
Query: 323 LKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEAP 382
+++ + +D+E+ L ++ D + S S K D+ED S + TE
Sbjct: 436 SQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQ-PALKATTDEEDSVSIIATEIK 494
Query: 383 QDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEPQKPEQPTPRKSP 442
++G SS KP K + F T + QKP P + +
Sbjct: 495 DGEKSGTV----SSRKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKP--PALKAT- 547
Query: 443 YGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGDEEGDLFKEKAVASPE-- 500
D++D S EE D K + V+S +
Sbjct: 548 -------------SDEEDSVLSIAR------------------EEKDGEKSRTVSSEQPP 576
Query: 501 ---ATVSQTDE--NKARAEKKVTLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASK 555
AT + D N AR +K K + SS + SD+E+S ++++ +
Sbjct: 577 GLKATRDEKDSLLNIARGKKY----GEKTRRVSSHKQPALKATSDKENSVPNMATETKDE 632
Query: 556 LKGASLLPGKLPTLVSLFDDEDEEDNLFGGTAAKKQTLCLQAQREEKAKASELSKKKASA 615
++ K P L + D +D N+ +Q+ + +Q++ KA+ + K S
Sbjct: 633 QISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQLAWKATSVKKDSVSN 692
Query: 616 LLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDEEDDLFA 675
+ + +SQ A ++ G+ +DS + ++E K +K+ ++
Sbjct: 693 IATEIKDGQIRGTVSSQRQPA--LKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKV 750
Query: 676 IAKDSQKKTQRVSLLFEDDVDSGGSLFGSP-PTSVPPATKKKE-------TVSEAPPLLF 727
I K ++VSLL +GG G+ P ++P E T ++ +
Sbjct: 751 IFK------KKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQT 804
Query: 728 SDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHSDLFSSSS 787
S E++ ++ + K++E + + + + + + +S+Q + D +
Sbjct: 805 STPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCN- 863
Query: 788 PWDKGTKPRTKTVLSLFDEEEDKMED 813
K V+ L D+ E K +D
Sbjct: 864 ---------CKNVILLIDQHEMKCKD 880
>gi|217035154 RCSD domain containing 1 [Homo sapiens]
Length = 416
Score = 57.0 bits (136), Expect = 1e-07
Identities = 58/185 (31%), Positives = 82/185 (44%), Gaps = 11/185 (5%)
Query: 934 ETPQDSSGLAPFKTKEPSTRIGKIQANLAINPAALLPTAASQISEVKPVLPELAFPSSEH 993
++P ++S FK K S I K+QANL +PAALLP A+ + +K ++ P S
Sbjct: 67 KSPPNASHPPKFKVKS-SPLIEKLQANLTFDPAALLPGASPKSPGLKAMVSPFHSPPST- 124
Query: 994 RRSHGLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQTRAARRLAAQES 1053
S G+ S P + E VSFD P + L NK R + KRRP +R RR
Sbjct: 125 PSSPGVRSRP--SEAEEVPVSFDQPPEGSHLPCYNKVRTRGSIKRRPPSRRFRR----SQ 178
Query: 1054 SETEDMSVPRGPIAQWADGAISPNGHR--PQLRAASGEDSTEEALAAAAAPWEG-GPVPG 1110
S+ ++ R + +GA +G P A G + E A G P
Sbjct: 179 SDCGELGDFRAVESSQQNGAKEEDGDEVLPSKSKAPGSPLSSEGAAGEGVRTLGPAEKPP 238
Query: 1111 VDRSP 1115
+ RSP
Sbjct: 239 LRRSP 243
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 55.5 bits (132), Expect = 3e-07
Identities = 60/250 (24%), Positives = 89/250 (35%), Gaps = 24/250 (9%)
Query: 208 EGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDG--CDLFADS 265
EG S S EE+ EE+E DED D + ++EE D C L+ADS
Sbjct: 964 EGEEASQESSSEKDEEDDEEDEEDEDREEAVDTTKKETEVSDGEDEESDSSSKCSLYADS 1023
Query: 266 EKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDAVGRVDEE----PTTLPSGEAKPRK 321
+ E + D E ++ S +S + ++ DEE P LPS PR+
Sbjct: 1024 DGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPPPRE 1083
Query: 322 TLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEA 381
TP+ E + P ++ +P + G ++ + L
Sbjct: 1084 V-----PVPTPAPVE---VPVPERVAGSPVTPLPEQEASPARPAGPTEESPPSAPL---R 1132
Query: 382 PQDRQAGASVKEESSSSKPGKKIP------AGAVSVFLGDTDVFGAASVPSMKEPQ-KPE 434
P + AG +P IP +V +V A P PQ K
Sbjct: 1133 PPEPPAGPPAPAPRPDERPSSPIPLLPPPKKRRKTVSFSAIEVVPAPEPPPATPPQAKFP 1192
Query: 435 QPTPRKSPYG 444
P RK+P G
Sbjct: 1193 GPASRKAPRG 1202
Score = 40.8 bits (94), Expect = 0.009
Identities = 60/276 (21%), Positives = 103/276 (37%), Gaps = 41/276 (14%)
Query: 314 SGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGL--FSGGKGL---- 367
S E K + K++ D E+ L P L+ D++ G G+ F+ G GL
Sbjct: 829 SKEEKAKPFQNAAKQQAKEEDKEKTKLKEPGLLSLVDWAKSGGTTGIEAFAFGSGLRGAL 888
Query: 368 ----FDDEDEESDLFTEAPQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAAS 423
F + +E +EA ++++ S E P ++ AG
Sbjct: 889 RLPSFKVKRKEPSEISEASEEKRPRPSTPAEEDEDDPEQEKEAGE-------------PG 935
Query: 424 VPSMKEPQKPE-----QPTPRKS-------PYGPPPTGLFDDDDGDDDDDFFSAPHSKPS 471
P K P++ E Q RKS + D++ D++D+
Sbjct: 936 RPGTKPPKRDEERGKTQGKHRKSFALDSEGEEASQESSSEKDEEDDEEDEEDEDREEAVD 995
Query: 472 KTGKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSET 531
T K +D DEE D + ++ + EN + ++ + + SSS + SS +
Sbjct: 996 TTKKETEVSD-GEDEESDSSSKCSLYA-----DSDGENDSTSDSESSSSSSSSSSSSSSS 1049
Query: 532 KTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLP 567
+ S E SED + + L AS P ++P
Sbjct: 1050 SSSSSSSSSESSSEDEEEEERPAALPSASPPPREVP 1085
Score = 37.7 bits (86), Expect = 0.075
Identities = 76/376 (20%), Positives = 129/376 (34%), Gaps = 92/376 (24%)
Query: 368 FDDEDEESDLFTEAPQDRQAGASVKEESSSSKPG--------KKIPAGAVSVFLGDTDVF 419
++ ++E++ F A + +QA KE++ +PG K + F + +
Sbjct: 827 WESKEEKAKPFQNAAK-QQAKEEDKEKTKLKEPGLLSLVDWAKSGGTTGIEAFAFGSGLR 885
Query: 420 GAASVPSMKEPQK-PEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQS 478
GA +PS K +K P + + P P+ ++D+ D + + + +P
Sbjct: 886 GALRLPSFKVKRKEPSEISEASEEKRPRPSTPAEEDEDDPEQEKEAGEPGRPG------- 938
Query: 479 TADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLF 538
P + + + + K L S + S E+ ++K
Sbjct: 939 ------------------TKPPKRDEERGKTQGKHRKSFALDSEGE-EASQESSSEK--- 976
Query: 539 SDEEDSEDLFSSQSASKLKGASLLPGKLPTLVSLFDDEDEEDNLFGGTAAKKQTLCLQAQ 598
DEED E+ DE++ED KK+T +
Sbjct: 977 -DEEDDEE----------------------------DEEDEDREEAVDTTKKETEVSDGE 1007
Query: 599 REEKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKA 658
EE +S K S S E D + S + +S S S S + S E+ +
Sbjct: 1008 DEESDSSS-----KCSLYADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSS 1062
Query: 659 VKKTSLFEEDEEDDLFAIAKDSQKKTQR---VSLLFEDDVDSGGSLFGSPPTSVP----- 710
EDEE++ A S R V +V + GSP T +P
Sbjct: 1063 --------EDEEEEERPAALPSASPPPREVPVPTPAPVEVPVPERVAGSPVTPLPEQEAS 1114
Query: 711 ---PATKKKETVSEAP 723
PA +E+ AP
Sbjct: 1115 PARPAGPTEESPPSAP 1130
Score = 35.8 bits (81), Expect = 0.28
Identities = 41/228 (17%), Positives = 83/228 (36%), Gaps = 38/228 (16%)
Query: 224 EKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKR 283
+ E EE+ ++ + D E + +E+E+D+ + D+ K+E ++ D E+
Sbjct: 962 DSEGEEASQESSSEKDEEDD-------EEDEEDEDREEAVDTTKKETEVSDGEDEESDSS 1014
Query: 284 SRPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAP 343
S+ + +AD + D+ + ++ S + + S ++E+ P
Sbjct: 1015 SKCSLYADSDG---ENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERP 1071
Query: 344 PKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEAP-----QDRQAGASV----KEE 394
L P E + T AP +R AG+ V ++E
Sbjct: 1072 AALPSASPPP-------------------REVPVPTPAPVEVPVPERVAGSPVTPLPEQE 1112
Query: 395 SSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEPQKPEQPTPRKSP 442
+S ++P S L + P+ + ++P P P P
Sbjct: 1113 ASPARPAGPTEESPPSAPLRPPEPPAGPPAPAPRPDERPSSPIPLLPP 1160
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 55.5 bits (132), Expect = 3e-07
Identities = 125/599 (20%), Positives = 228/599 (38%), Gaps = 107/599 (17%)
Query: 205 SSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFAD 264
S E V +RG +++ +E EEE +E+ + E+ +EEED++ +
Sbjct: 1048 SPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEE--------EEEEDEE-----EE 1094
Query: 265 SEKEEEDIEDIEENTRPKRSRPTSFADE-----LAARIKGDAVGRVDEEPTTLPSGEAKP 319
E+EEE+ E+ +++ P+ ++P S A + + + +G R++ TT
Sbjct: 1095 EEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTT-------- 1146
Query: 320 RKTLKEKKERRTPSDDEEDNLFAPPKL--------TDEDFSPFGSGGGLFSGGKGLFDDE 371
+T+ E E D D P+L ++ P GK +E
Sbjct: 1147 -ETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKKRQTEE 1205
Query: 372 DEESD--LFTEAPQDRQAGASVKEESSSSKPGKK---IPAGAVSVFLGDTDVFGAASVPS 426
+E D F A R ++ ++SS+ K G K P V+ T
Sbjct: 1206 EEGKDNHCFKNADPCRN---NMNDDSSNLKEGSKDNPEPLKCKQVWPKGT------KRGL 1256
Query: 427 MKEPQKPEQPTPRK-SPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGD 485
K Q E+ T K + Y PP T + + D+ + K + GK S + I +
Sbjct: 1257 SKWRQNKERKTGFKLNLYTPPETPM-------EPDEQVTVEEQKETSEGKT-SPSPIRIE 1308
Query: 486 EEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSE-TKTQKGLFSDEEDS 544
EE KE + EA + Q + + V+ ++S KP + K ++ +EE+
Sbjct: 1309 EE---VKE----TGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEE 1361
Query: 545 EDLFSSQSASKLKGASLLPGKLPTLVSLFDDEDEEDNLFGGTAAKKQTLCLQAQREEKAK 604
E+ ++E+E + GG +K ++Q +E+ +
Sbjct: 1362 EE---------------------------EEEEEGEEEEGGGNVEKDPDGAKSQEKEEPE 1394
Query: 605 ASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTSL 664
S ++K+ SA L +EE++ + S ++ + DS ++ K
Sbjct: 1395 IS--TEKEDSARLDDHEEEEEEDEEPSH----NEDHDADDEDDSHMESAEVEKEELPRES 1448
Query: 665 FEEDEEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVSEAPP 724
F+E E+ + + Q +L + VD S P E+ E PP
Sbjct: 1449 FKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVPESDEEPPP 1508
Query: 725 LLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHSDLF 783
++ +K+ Q K VD + + + T +SE + QE+ + D F
Sbjct: 1509 ---GEQAQKQDQKNSKEVDTEFKEGNPA-----TMEIDSETVQAVQSLTQESSEQDDTF 1559
Score = 46.2 bits (108), Expect = 2e-04
Identities = 43/158 (27%), Positives = 67/158 (42%), Gaps = 36/158 (22%)
Query: 194 MEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEE 253
+E++ G EE + +++ ++ +EEEE DE+ +H+ D+ D +
Sbjct: 1378 VEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDH----------DAD 1427
Query: 254 EDDDGCDLFADSEKEEEDIEDIEE-----------NTRPKRSRPTSFAD---ELAA---- 295
++DD A+ EKEE E +E N +P S P D +L A
Sbjct: 1428 DEDDSHMESAEVEKEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNS 1487
Query: 296 ---RIKGD--AVGRVDEEPTTLPSGEAKPRKTLKEKKE 328
+ GD AV DEEP P GE ++ K KE
Sbjct: 1488 EPKELAGDPEAVPESDEEP---PPGEQAQKQDQKNSKE 1522
Score = 40.0 bits (92), Expect = 0.015
Identities = 126/670 (18%), Positives = 235/670 (35%), Gaps = 130/670 (19%)
Query: 96 ENRVYDEEVEEPVLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKA 155
E DEE EE + E ++ E+E+ E++E + I + V +K
Sbjct: 1072 EEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKK 1131
Query: 156 G--------NSDSEEDDANGRVELILEPKD-LYIDRPLPYLIGSKLFMEQEDVGLGELSS 206
NS + + E++ EP D +RP+P L + +ED G
Sbjct: 1132 KRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEED---GRKPV 1188
Query: 207 EEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDD--------- 257
+ G TEEE+ ++ A N N ++ + + +D+
Sbjct: 1189 LRKAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVW 1248
Query: 258 ---------------------GCDLFADSEKEEEDIEDI----EENTRPKRSRPTSFADE 292
+L+ E E E + ++ T ++ P+ E
Sbjct: 1249 PKGTKRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIE 1308
Query: 293 LAARIKGDAVGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFS 352
+ G+A+ LP E + +T +P + ED+L P + +E
Sbjct: 1309 EEVKETGEAL---------LPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEE--- 1356
Query: 353 PFGSGGGLFSGGKGLFDDEDEESDLFTEAPQDRQAGASVKEESSSSKPGKKIPAGAVSVF 412
+E+EE + E ++ + G +V+++ +K +K +S
Sbjct: 1357 -----------------EEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEK-EEPEISTE 1398
Query: 413 LGDTDVFGAASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSK 472
D+ A +E ++ E+P+ +D D DD+DD +
Sbjct: 1399 KEDS----ARLDDHEEEEEEDEEPSHN------------EDHDADDEDDSHMESAEVEKE 1442
Query: 473 TGKVQSTADIFGDEEG--DLFKEKAVASPEA--------TVSQTDENKARA-EKKVTLSS 521
+S ++ ++E DL + ++PE T S E K A + + S
Sbjct: 1443 ELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVPES 1502
Query: 522 SKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLPTLVSLFDDEDEEDN 581
+ P + + Q S E D+E + + ++ + + + SL + E+D+
Sbjct: 1503 DEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSET-----VQAVQSLTQESSEQDD 1557
Query: 582 LFGGTAAKKQTLCLQAQREEKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRS 641
F A+ Q C Q +A + S + A+ L + + + +H RS
Sbjct: 1558 TF-QDCAETQEACRSLQNYTRA---DQSPQIATTLDDCQQSDHSSPVSSVHSHPGQSVRS 1613
Query: 642 KGEP-----RDSGTLQSQEAKAVKKTSL--FEEDEEDDLFAIAKDSQKKTQRVSLLFEDD 694
P +S S + A+ SL E D+ +++ SQ+
Sbjct: 1614 VNSPSVPALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQV----------- 1662
Query: 695 VDSGGSLFGS 704
VDSG S GS
Sbjct: 1663 VDSGFSDLGS 1672
>gi|239747798 PREDICTED: hypothetical protein XP_002348316 [Homo
sapiens]
Length = 399
Score = 53.9 bits (128), Expect = 1e-06
Identities = 66/292 (22%), Positives = 121/292 (41%), Gaps = 50/292 (17%)
Query: 492 KEKAVASPEATVSQTDENKARAEKKVTLSSSKNLK---PSSETKTQKGLFSDEEDSEDLF 548
K V+S + S+ +K + + L+ SS+ + +DEEDS
Sbjct: 106 KSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNI 165
Query: 549 SSQSASKLKGASLLPGKLPTLVSLFDDEDE--------EDNLFGGTAAKKQTLCLQAQRE 600
+++ K ++ K P L + D+ED +D T + ++ L+A +
Sbjct: 166 ATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTD 225
Query: 601 EK-------------AKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRD 647
E+ K+ +S +K AL +SDE+D + ++ +R K +
Sbjct: 226 EEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSF---------SNITREKKDGEI 276
Query: 648 SGTLQSQEAKAVKKTSLFEEDEEDDLFAIA--KDSQKKTQRVS-------LLFEDDVDSG 698
S T+ S++ +K TS DEED + IA K+ +KT+RVS D+ DS
Sbjct: 277 SRTVTSEKPAGLKATS----DEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSDEKDS- 331
Query: 699 GSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAK 750
F + + S+ PP L + +E+++ L + +K E ++
Sbjct: 332 ---FSNITREKKDGETSRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSR 380
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 53.5 bits (127), Expect = 1e-06
Identities = 86/383 (22%), Positives = 153/383 (39%), Gaps = 51/383 (13%)
Query: 589 KKQTLCLQAQREEKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDS 648
KK T + +++EK + L+K++ A EE + KG ++
Sbjct: 182 KKATHKEKIEKKEKPETKTLAKEQKKAKTAEKSEEK------------TKKEVKGGKQEK 229
Query: 649 GTLQSQEAKAVKKTSLFEEDEEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTS 708
+ + K V+KT +++ED A ++K Q + D+ G L +
Sbjct: 230 VKQTAAKVKEVQKTPSKPKEKEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPA 289
Query: 709 VPP--ATKKKETVSEAPPLLFSDE-EEKEAQLGVKSVDKKVES---AKESLKFGRTDVAE 762
+PP T++ + A P L E E+K+A+ V S KK E K+S K DV E
Sbjct: 290 IPPPLPTEQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDV-E 348
Query: 763 SEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQK 822
++ G + + Q TVK + ++ K +TK + + K E + +K
Sbjct: 349 KKEPGKASETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKK------EK 402
Query: 823 EVGKGRDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGT------KKTKLLEPSVG 876
V + P K V D+++ + K+ V + K TK +E +
Sbjct: 403 HVEPAKSP---KKEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTTKTVEQEIR 459
Query: 877 SLFGDDEDDDLFSSAKSQPLVQEKKRVVKKDHSVDSFKNQKHPESIQG---SKEKGIWKP 933
S K+ ++++K+ + K+ V + +K PE+ + SK KP
Sbjct: 460 K----------EKSGKTSSILKDKEPIKGKEEKVPASLKEKEPETKKDEKMSKAGKEVKP 509
Query: 934 ETPQDSSGLAPFKTKEPSTRIGK 956
+ PQ L K ++P +I K
Sbjct: 510 KPPQ----LQGKKEEKPEPQIKK 528
Score = 45.8 bits (107), Expect = 3e-04
Identities = 117/553 (21%), Positives = 207/553 (37%), Gaps = 100/553 (18%)
Query: 452 DDDDGDDDDD----------------FFSAPHSKPSKTGKVQSTADIFGDEEG-DLFKEK 494
+DDDGD+D D + KP + K+Q+ E+G + +EK
Sbjct: 120 EDDDGDEDTDKGEIDEPPLRKKEIHKDKTEKQEKPER--KIQTKVTHKEKEKGKEKVREK 177
Query: 495 AVASPEATVSQTDENKARAEKKVTLSSSKNLKPS--SETKTQKGLFSDEEDSEDLFSSQS 552
+AT + E K + E K K K + SE KT+K + +++ Q+
Sbjct: 178 EKPEKKATHKEKIEKKEKPETKTLAKEQKKAKTAEKSEEKTKKEVKGGKQEK----VKQT 233
Query: 553 ASKLKGASLLPG-------KLPTLVSLFDDEDEE-------DNLFGGTAAKKQTLCL--- 595
A+K+K P K VS + +D+ D G Q+ +
Sbjct: 234 AAKVKEVQKTPSKPKEKEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPPP 293
Query: 596 ----QAQR--------EEKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKG 643
QA R EEK + ++KK ++ ++ED +T + + + G
Sbjct: 294 LPTEQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEPG 353
Query: 644 EPRDS--GTLQSQEAKAVKKTSLFEEDEEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSL 701
+ ++ GT++ A KK DE+ K+ KKT++ + E + G
Sbjct: 354 KASETKQGTVKIAAQAAAKK------DEK-------KEDSKKTKKPA---EVEQPKGKKQ 397
Query: 702 FGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVA 761
P + KKE + + + E + ++G S+ K V KE K +T
Sbjct: 398 EKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEE-KTTKTVEQ 456
Query: 762 ESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQ 821
E KE ++ K S + P KG + K SL ++E + +D+ + +A
Sbjct: 457 EIRKE--------KSGKTSSILKDKEP-IKGKE--EKVPASLKEKEPETKKDEKMSKA-- 503
Query: 822 KEVGKGRDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGD 881
GK + PK + +E +++K+ P + K +++P G
Sbjct: 504 ---GK----EVKPKPPQLQGKKEEKPEPQIKKEAKPAISEKVQIHKQDIVKPEKTVSHGK 556
Query: 882 DEDDDLFS-SAKSQPLVQEKKRVVKKDHSVDSFKNQKHPESIQGSKEKGIWKPETPQDSS 940
E+ L A + + K K +H ++ P SI+ K K K + S
Sbjct: 557 PEEKVLKQVKAVTIEKTAKPKPTKKAEH------REREPPSIKTDKPKPTPKGTSEVTES 610
Query: 941 GLAPFKTKEPSTR 953
G + E ++
Sbjct: 611 GKKKTEISEKESK 623
Score = 35.8 bits (81), Expect = 0.28
Identities = 78/386 (20%), Positives = 145/386 (37%), Gaps = 55/386 (14%)
Query: 102 EEVEEPVLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFE--QLDIK-AGNS 158
EE E KAE + T + K +E++++ + + A++ + A E Q +K A +
Sbjct: 310 EEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEPGKASETKQGTVKIAAQA 369
Query: 159 DSEEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSI 218
+++D+ + +P + +++P G K +++ V + +E SV SD+
Sbjct: 370 AAKKDEKKEDSKKTKKPAE--VEQPK----GKKQEKKEKHVEPAKSPKKEHSVPSDKQVK 423
Query: 219 VDTEEEKE---------------EEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFA 263
TE KE EE++ + E++ T+ + ++E G +
Sbjct: 424 AKTERAKEEIGAVSIKKAVPGKKEEKTTKTVEQEIRKEKSGKTSSILKDKEPIKGKEEKV 483
Query: 264 DS---EKEEEDIEDIEENTRPKRSRPT------SFADELAARIKGDAVGRVDEEPTTLPS 314
+ EKE E +D + + K +P ++ +IK +A + E+
Sbjct: 484 PASLKEKEPETKKDEKMSKAGKEVKPKPPQLQGKKEEKPEPQIKKEAKPAISEKVQIHKQ 543
Query: 315 GEAKPRKTLK-----------------EKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSG 357
KP KT+ EK + P+ E PP + + P G
Sbjct: 544 DIVKPEKTVSHGKPEEKVLKQVKAVTIEKTAKPKPTKKAEHREREPPSIKTDKPKPTPKG 603
Query: 358 -GGLFSGGKGLFDDEDEESDLFTEAPQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDT 416
+ GK + ++ES + R+ S ++ES K A
Sbjct: 604 TSEVTESGKKKTEISEKESKEKADMKHLREEKVSTRKESLQLHNVTKAEKPA----RVSK 659
Query: 417 DVFGAASVPSMKEPQKPEQPTPRKSP 442
DV + KE + PT +KSP
Sbjct: 660 DVEDVPASKKAKEGTEDVSPTKQKSP 685
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 53.1 bits (126), Expect = 2e-06
Identities = 121/661 (18%), Positives = 247/661 (37%), Gaps = 93/661 (14%)
Query: 196 QEDVGLGELSSE-EGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEE 254
++D+ L L++E EG+ + ++ +K++E+ +DF ++ + + +
Sbjct: 14 KDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQGIK 73
Query: 255 DDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDAVGRVDEEPTTLPS 314
D +E EE+ ++ + ++ + SF D + L
Sbjct: 74 ADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDN---------------DSEELED 118
Query: 315 GEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEE 374
++K +KT K K E + SDD++D P K G S K +EDE+
Sbjct: 119 KDSKSKKTAKPKVEMYSGSDDDDDFNKLPKK---------AKGKAQKSNKKWDGSEEDED 169
Query: 375 -SDLFTEAPQDRQAGASVKE------------ESSSSKPGKKIPAGAVSVFLGDTDVFGA 421
S E + +G S E ++ +KPG I +G D D
Sbjct: 170 NSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGN-----EDDDASFK 224
Query: 422 ASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTAD 481
+ K+ +K E+ ++ ++ + +TGK +
Sbjct: 225 IKTVAQKKAEKKERERKKRD---------------EEKAKLRKLKEKEELETGKKDQSKQ 269
Query: 482 IFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSDE 541
E F+E+ V S + TV T A EK T +++++ + K K E
Sbjct: 270 ---KESQRKFEEETVKS-KVTV-DTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGE 324
Query: 542 EDSEDLFSSQSASKLKGASLLPGKLPTLVSLFDDEDEEDNLFGGTAAKKQTLCLQAQREE 601
++ ++ + SK + + L L ++E+ + + + L + + EE
Sbjct: 325 KEEKEKEKKKGPSK----ATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEE 380
Query: 602 KAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKK 661
+ + + +KK E+++ + L + S+ + R TL+ +A+ V+
Sbjct: 381 RLEQEKRERKK-------QKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEV 433
Query: 662 TSLFEEDEEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVSE 721
S ++ ++ + +K+ + L +V L + +K+ET
Sbjct: 434 PSKDSLPKKRPIY----EDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEET--- 486
Query: 722 APPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHSD 781
PP + +EEE G+ + + S +E+ K V KE +E + D
Sbjct: 487 -PPPVEPEEEEDTEDAGLDDWE-AMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEED 544
Query: 782 LFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQ-----NIIQAPQKEVGKGRDPDAHPKS 836
S ++G ++ DEE++K+ D+ + + P KE+ + D+
Sbjct: 545 EESEEEEEEEGESEGSEG-----DEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDR 599
Query: 837 T 837
T
Sbjct: 600 T 600
Score = 40.4 bits (93), Expect = 0.012
Identities = 76/436 (17%), Positives = 175/436 (40%), Gaps = 57/436 (13%)
Query: 108 VLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANG 167
V + +AEK E+E+ + +E + K++E ++ +Q K EE+
Sbjct: 228 VAQKKAEKKERERKKRDEEKAKLRKLKEKE----ELETGKKDQSKQKESQRKFEEETVKS 283
Query: 168 RVEL---ILEPKDLYIDRPLPYLIGSKLFMEQED----VGLGELSSEEGSVGSDRGSIVD 220
+V + ++ + + P ++ +++D G E +E G + ++
Sbjct: 284 KVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKA 343
Query: 221 TEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTR 280
+E + + +E+ + E+ + ++ + ++++ + ++E + ++ E R
Sbjct: 344 MQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLE---QEKRERKKQKEKERKER 400
Query: 281 PKRSRPTSFADELAARIKGDAVGR-VDEEPTTLPSGEAKPRK--TLKEKKERRTPSDDEE 337
K+ + AR + +A + + + +PS ++ P+K ++KK ++ P E
Sbjct: 401 LKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLES 460
Query: 338 DNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEAPQDRQ-AGASVKEESS 396
+ +L + +G+ + E+ + E +D + AG E +
Sbjct: 461 KEVSESMELC----------AAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMA 510
Query: 397 SSKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDG 456
S + +K+ V + + + P +E ++ E+ +S G + +G
Sbjct: 511 SDEETEKVEGNKVHIEVKEN--------PEEEEEEEEEEEEDEESEEEEEEEGESEGSEG 562
Query: 457 DDDDDFFS-------APHSKPSKTGKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDEN 509
D++D+ S KPSK + ++D D + D KE+ D+
Sbjct: 563 DEEDEKVSDEKDSGKTLDKKPSK----EMSSDSEYDSDDDRTKEERA---------YDKA 609
Query: 510 KARAEKKVTLSSSKNL 525
K R EK+ L SKN+
Sbjct: 610 KRRIEKR-RLEHSKNV 624
Score = 40.0 bits (92), Expect = 0.015
Identities = 94/474 (19%), Positives = 182/474 (38%), Gaps = 59/474 (12%)
Query: 110 KAEAEKTEQEKTREQKEVDLIPKVQEA--VNYGLQVLDSAFEQLDIKAGN---------- 157
K +A+K+ ++ +++ D K++E +N + D + E L + G
Sbjct: 151 KGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGP 210
Query: 158 ---SDSEEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSS-EEGSVGS 213
S +E+DDA+ +++ + + K +R + ++E L +L EE G
Sbjct: 211 NIESGNEDDDASFKIKTVAQKKAEKKER-------ERKKRDEEKAKLRKLKEKEELETGK 263
Query: 214 DRGSIVDTEEEKEEEESDE-----DFAHHSDNEQNRHTTQMSDEEEDDDGCDLFADSEKE 268
S + K EEE+ + D +E+ T + E+D++G D +K+
Sbjct: 264 KDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAA--EDDNEGDKKKKDKKKK 321
Query: 269 EEDIEDIEENTRPKRSRPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRKTLKEKKE 328
+ + E+ E+ + S+ T A + +A+ ++ EE E + K L+E +
Sbjct: 322 KGEKEEKEKEKKKGPSKATVKAMQ-------EALAKLKEEEERQKREEEERIKRLEELEA 374
Query: 329 RRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEAPQDRQAG 388
+R + E K +++ L GK L E+ EA
Sbjct: 375 KRKEEERLEQEKRERKKQKEKERKE-----RLKKEGK-LLTKSQREARARAEATLKLLQA 428
Query: 389 ASVKEESSSSKPGK----------KIPAGAVSVFLGDT-DVFGAASVPSMKEPQKPEQPT 437
V+ S S P K KIP S + ++ ++ A V P+K E P
Sbjct: 429 QGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPP 488
Query: 438 P--RKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPS---KTGKVQSTADIFGDEEGDLFK 492
P + GL D + D++ +K K + + +EE + +
Sbjct: 489 PVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESE 548
Query: 493 EKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSDEEDSED 546
E+ E+ S+ DE + + + + KPS E + SD++ +++
Sbjct: 549 EEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKE 602
Score = 38.9 bits (89), Expect = 0.034
Identities = 45/222 (20%), Positives = 94/222 (42%), Gaps = 45/222 (20%)
Query: 98 RVYDEEVEEPVLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGN 157
R +E +E+ + + +K ++ K R +KE L+ K Q + + ++ +
Sbjct: 376 RKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPS 435
Query: 158 SDS-------EEDDANGRVELILEPKDLYIDRPL-----------------PYLIGSKLF 193
DS ED ++ LE K++ L P + +
Sbjct: 436 KDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEE 495
Query: 194 MEQEDVGLGE---LSSEEGSVGSDRGSI-----VDTEEEKEEEESDEDFAHHSDNEQNRH 245
+ ED GL + ++S+E + + + + EEE+EEEE +E+ D E
Sbjct: 496 EDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEE-----DEE---- 546
Query: 246 TTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPT 287
S+EEE+++G ++ ++E+E + D +++ + +P+
Sbjct: 547 ----SEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPS 584
Score = 36.6 bits (83), Expect = 0.17
Identities = 63/286 (22%), Positives = 108/286 (37%), Gaps = 46/286 (16%)
Query: 730 EEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLL----TRSAQETVKHSDLFSS 785
E+E + G K +KK + E + E +G+ T + + T + + F+S
Sbjct: 34 EQEPQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQGIKADRETVAVKPTENNEEEFTS 93
Query: 786 SSPWDKGTKPRTKTVLSLFDEE-EDKMEDQNIIQAPQKEVGKGRDPD------------- 831
KG K + ++ EE EDK P+ E+ G D D
Sbjct: 94 KDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGK 153
Query: 832 ---AHPKSTGVFQDEE----------LLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSL 878
++ K G +DE+ + S + ++D + G KK + +P
Sbjct: 154 AQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIE 213
Query: 879 FGDDEDDDLFS-SAKSQPLVQEKKRVVKK-DHSVDSFKNQKHPESIQGSKEKGIWKPETP 936
G+++DD F +Q ++K+R KK D + K E ++ K K ++
Sbjct: 214 SGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGK-----KDQSK 268
Query: 937 QDSSGLAPFKTKEPSTRIGKIQANLAINPA----ALLPTAASQISE 978
Q S + E T K+ + + PA A PTAA +E
Sbjct: 269 QKESQ----RKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNE 310
Score = 34.3 bits (77), Expect = 0.83
Identities = 51/230 (22%), Positives = 80/230 (34%), Gaps = 30/230 (13%)
Query: 737 LGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPR 796
+G K +K +S K+ + D +E EG QE K KG K +
Sbjct: 1 MGKKQKNKSEDSTKDDIDL---DALAAEIEGAGAAKEQEPQK-----------SKGKKKK 46
Query: 797 TKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGRDPDAHPKSTGVFQDEELLFSHKLQK--- 853
K +E+D +++ + + + R+ A + +EE K +K
Sbjct: 47 EKKKQDF--DEDDILKELEELSLEAQGIKADRETVAVKPTEN--NEEEFTSKDKKKKGQK 102
Query: 854 -------DNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEK--KRVV 904
DND + +K K +P V G D+DDD K +K K+
Sbjct: 103 GKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWD 162
Query: 905 KKDHSVDSFKNQKHPESIQGSKEKGIWKPETPQDSSGLAPFKTKEPSTRI 954
+ D+ K K I S E G E Q G + +P I
Sbjct: 163 GSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNI 212
Score = 33.9 bits (76), Expect = 1.1
Identities = 38/140 (27%), Positives = 58/140 (41%), Gaps = 15/140 (10%)
Query: 1176 GEASSDDDLFQSAKPKPAKKTNPFPLLEDEDDLFTDQKVKKNETKS--NSQQDVILTTQD 1233
G A + K K KK F DEDD+ + + E + ++ V + +
Sbjct: 30 GAAKEQEPQKSKGKKKKEKKKQDF----DEDDILKELEELSLEAQGIKADRETVAVKPTE 85
Query: 1234 IFEDDIFATEAIKPSQKTREKEKTLESNLFDDN-IDIFADLTVKPKEKSKKKVEAKSIFD 1292
E++ + + K QK +++ FDDN + D K K+ +K KVE S D
Sbjct: 86 NNEEEFTSKDKKKKGQKGKKQS-------FDDNDSEELEDKDSKSKKTAKPKVEMYSGSD 138
Query: 1293 DDMDDIFSSGIQAKTTKPKS 1312
DD DD +AK KS
Sbjct: 139 DD-DDFNKLPKKAKGKAQKS 157
>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
precursor [Homo sapiens]
Length = 497
Score = 52.0 bits (123), Expect = 4e-06
Identities = 92/427 (21%), Positives = 159/427 (37%), Gaps = 52/427 (12%)
Query: 251 DEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDAVGRVDEEPT 310
D++EDD G D F D + +D +E + D + A + G+ + T
Sbjct: 87 DDDEDDSGDDTFGDDDSGPGP-KDRQEGGNSRLGSDEDSDDTIQASEESAPQGQDSAQDT 145
Query: 311 TLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDD 370
T S E + K E + + E ++E + GS G G DD
Sbjct: 146 TSESRELDNEDRVDSKPEGGDSTQESE---------SEEHWVGGGSDGESSHGDGSELDD 196
Query: 371 EDEESDLFTEAPQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEP 430
E +SD D ++ S + S + G K + +T G + +
Sbjct: 197 EGMQSD-------DPESIRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQL-----L 244
Query: 431 QKPEQPTPRKSPYG-PPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGDEEGD 489
+ P + RKS DD++ ++ S +S TG Q D GD + D
Sbjct: 245 EHPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQED 304
Query: 490 ----LFKEK--------AVASPEATVSQTDENKARAEKKVTLSSSKNLKP-SSETKTQKG 536
L +E+ + +S EA +S + + E+ V+ S N P +S + Q+
Sbjct: 305 SKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQED 364
Query: 537 LFSDEEDSEDLFS-SQSASKLKGASLLPGKLPTLVSLFDDEDEEDNLFGGTAAKKQTLCL 595
S EEDS S S+S S+ + A + + E++N + +
Sbjct: 365 SDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSA 424
Query: 596 QAQREEKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQE 655
++Q EE + S + S S +ED ++ + SK + G L++ E
Sbjct: 425 ESQSEESHSEEDDSDSQDS----SRSKED-----------SNSTESKSSSEEDGQLKNIE 469
Query: 656 AKAVKKT 662
++ K T
Sbjct: 470 IESRKLT 476
Score = 38.5 bits (88), Expect = 0.044
Identities = 86/408 (21%), Positives = 144/408 (35%), Gaps = 62/408 (15%)
Query: 356 SGGGLFSGGKGLFDDEDEESDLFTEAPQDRQAGASVK--EESSSSKPGKKIPAGAVSVFL 413
+GG S GKG D +D+E D + D +G K +E +S+ G
Sbjct: 72 AGGFSRSTGKGGDDKDDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSD---------- 121
Query: 414 GDTDVFGAASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKT 473
D+D AS S + Q Q T +S + D++D S P S
Sbjct: 122 EDSDDTIQASEESAPQGQDSAQDTTSES------------RELDNEDRVDSKPEGGDSTQ 169
Query: 474 GKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKP------ 527
+ G +G+ + + D R+E+ + +S +K
Sbjct: 170 ESESEEHWVGGGSDGESSHGDGSELDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGEN 229
Query: 528 SSETKTQKGLFSD--EEDSEDLFSSQSASKLKGASLLPGKLPTLVSLFDDEDEEDNLFGG 585
S + TQ S E S +F S+ S L T+ + D E N
Sbjct: 230 SEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDN-NTMEEVKSDSTENSN---- 284
Query: 586 TAAKKQTLCLQAQREEKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEP 645
+ T Q +R+ K + E SK+ S +E + P+S++ ++ S+
Sbjct: 285 ---SRDTGLSQPRRDSKGDSQEDSKEN-----LSQEESQNVDGPSSESSQEANLSSQENS 336
Query: 646 RDSGTLQSQEAKA--VKKTSLFEEDEEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFG 703
+S E++ T+ + ED+ED + S + S E+ DS S
Sbjct: 337 SESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESS--- 393
Query: 704 SPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKE 751
+ E E+P ++E +Q G++S ES E
Sbjct: 394 -------ESLNFSEESPESP-----EDENSSSQEGLQSHSSSAESQSE 429
Score = 38.1 bits (87), Expect = 0.057
Identities = 90/406 (22%), Positives = 147/406 (36%), Gaps = 78/406 (19%)
Query: 452 DDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGDEE--GDLFKEKAVASPEATVSQTDEN 509
DDD+ D DD F S P + + G +E D + ++P+ S D
Sbjct: 87 DDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDEDSDDTIQASEESAPQGQDSAQD-- 144
Query: 510 KARAEKKVTLSSSKNL--KPSSETKTQKGLFSDEEDSEDLF---SSQSASKLKGASLLPG 564
T S S+ L + ++K + G + E +SE+ + S S S L
Sbjct: 145 --------TTSESRELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGSELDD 196
Query: 565 KLPTLVSLFDDEDEEDNLFGGTAAKKQTLCLQAQREEKAKASELSKKKASALLFS----- 619
+ + D+ E G + + E ++ + S LL
Sbjct: 197 E-----GMQSDDPESIRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKI 251
Query: 620 ------SDEEDQWNIPASQT--HLASDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDEED 671
S+E+D+ + + T + SDS RD+G SQ + K S +ED ++
Sbjct: 252 FRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGL--SQPRRDSKGDS--QEDSKE 307
Query: 672 DLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVSEA------PPL 725
+L SQ+++Q V D S S + + + ++E VSE+ P
Sbjct: 308 NL------SQEESQNV-----DGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTT 356
Query: 726 LF--------SDEEEKEAQLGVKSVDKKVESA----KESLKFGR------TDVAESEKEG 767
+ S EE+ L + + E A ESL F D S +EG
Sbjct: 357 SYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEG 416
Query: 768 LLTRS----AQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEED 809
L + S +Q HS+ S S +K + + S EED
Sbjct: 417 LQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEED 462
Score = 34.7 bits (78), Expect = 0.63
Identities = 42/186 (22%), Positives = 81/186 (43%), Gaps = 26/186 (13%)
Query: 157 NSDSEEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRG 216
N S+E+ + + E++ E + D P P + +QED SSEE S +
Sbjct: 329 NLSSQENSSESQEEVVSESRG---DNPDPT---TSYVEDQEDSD----SSEEDSSHTLSH 378
Query: 217 SIVDTEEEKEEEESDE--DFAHHS-DNEQNRHTTQMSDEEEDDDGCDLFADSEKEEEDIE 273
S ++ EE+ + ES E +F+ S ++ ++ +++ + + ++ EED
Sbjct: 379 SKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDS 438
Query: 274 DIEENTRPKRSRPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRKTLKEKKERRTPS 333
D ++++R K D + K + EE L + E + RK + + P
Sbjct: 439 DSQDSSRSKE-------DSNSTESKSSS-----EEDGQLKNIEIESRKLTVDAYHNK-PI 485
Query: 334 DDEEDN 339
D++DN
Sbjct: 486 GDQDDN 491
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 51.2 bits (121), Expect = 7e-06
Identities = 99/493 (20%), Positives = 185/493 (37%), Gaps = 43/493 (8%)
Query: 694 DVDSGGSLFGSPPTSVPPATKKKETVSEA--PPLLFSDEEEKEAQLGVKSVDKKVESAKE 751
D D G S G+ P A + + SE P D +E E + +S D + A+
Sbjct: 1823 DQDPGQS-DGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEG 1881
Query: 752 SLKFGRTDVAESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKM 811
A+ E E + T A+ V+ + + +K +P T++V +L E ED+
Sbjct: 1882 E--------AQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEP 1933
Query: 812 EDQNIIQAPQKEVGKGRDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLL 871
E + +E + + P+S E++ S + +++ P+ + +
Sbjct: 1934 ESEGAEAQEAEEAAQEAEGQTQPES-------EVIESQEAEEEAQPESEDVEALEVEVET 1986
Query: 872 EPSVGSLFGDDEDDDLFSSAKSQPLVQEKKRVVKKDHSVDSFKNQKHPESIQGSKEKGIW 931
+ + G + ED + + +E+ + + + ++G +K
Sbjct: 1987 QEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQK--T 2044
Query: 932 KPETPQDSSGL-APFKTKEPSTRIGKIQ-ANLAINPAALLPTAASQISEVKPVLPELAFP 989
+ + +S G+ AP +E G++Q A +P + A E +P + P
Sbjct: 2045 EGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAP 2104
Query: 990 SS--EHRRSHGLESVPVLPGSGE---AGVSFDLPAQADTLHSANKSRVKMRGKRRPQTRA 1044
+ E +++ G+E+ P G + G+ S G+ +P++
Sbjct: 2105 EAEGEAQKAEGIEA-PETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEG 2163
Query: 1045 ARRLAAQESSETEDMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTE-EALAAAAAPW 1103
A+E ++ E G A A+G P + A GE E E + A A
Sbjct: 2164 IEAQEAEEEAQPE----LEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEE 2219
Query: 1104 EGGPVPGVDRSPFA------KSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAEN 1157
E P P +P A +S G ++GE S G G QS E ++ + + E+
Sbjct: 2220 EAQPEPEGVETPEAEGEAQPESEGETQGEK---KGSPQVSLGDG-QSEEASESSSPVPED 2275
Query: 1158 PANPPVGGKAKSP 1170
PP +P
Sbjct: 2276 RPTPPPSPGGDTP 2288
Score = 49.3 bits (116), Expect = 2e-05
Identities = 97/446 (21%), Positives = 156/446 (34%), Gaps = 102/446 (22%)
Query: 102 EEVEEPVLKAEAEKTEQEKTREQKEVDLIPK-----VQEAVNYGLQVLDSAFEQLD-IKA 155
E+VE P + E ++ E+E E V+ PK QE + A + D ++A
Sbjct: 1998 EDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEA 2057
Query: 156 GNSDSEEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDR 215
++ E +A G V+ + E EDV + EG +
Sbjct: 2058 PEAEEEAQEAEGEVQ----------------EAEGEAHPESEDV---DAQEAEGEAQPES 2098
Query: 216 GSIVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFADSEKEEEDIEDI 275
+ E E E ++++ A ++ E + + E + + A E E + +D
Sbjct: 2099 EGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGE-----AQPESEGVEAQDA 2153
Query: 276 EENTRPKRSRPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDD 335
E +P+ + E A+ + + V + E GEA+P E E +
Sbjct: 2154 EGEAQPESEGIEAQEAEEEAQPELEGVEAPEAE------GEAQPESEGIEAPEAEGEAQP 2207
Query: 336 EEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEAPQDRQAGASVKEES 395
E + + AP + +EE+ E + +A + ES
Sbjct: 2208 ELEGVEAP--------------------------EAEEEAQPEPEGVETPEAEGEAQPES 2241
Query: 396 SSSKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDDD 455
G+K G+ V LGD +E + P P P PP G
Sbjct: 2242 EGETQGEK--KGSPQVSLGD---------GQSEEASESSSPVPEDRPTPPPSPG------ 2284
Query: 456 GDDDDDFFSAPHSKP-SKTGKVQSTADIFG-----DEEGDLFKEKAVASPEATVSQTDEN 509
GD PH +P S+TG S A +G D E D SP+A + T
Sbjct: 2285 GD-------TPHQRPGSQTGPSSSRASSWGNCWQKDSENDHVLGD-TRSPDAKSTGT--- 2333
Query: 510 KARAEKKVTLSSSKNLKPSSETKTQK 535
AE+K T + P S T Q+
Sbjct: 2334 -PHAERKAT-----RMYPESSTSEQE 2353
>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
Length = 2039
Score = 49.7 bits (117), Expect = 2e-05
Identities = 99/495 (20%), Positives = 192/495 (38%), Gaps = 73/495 (14%)
Query: 488 GDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSDEEDSEDL 547
G+ F+ V++T+E + +++V LS SE + Q S +++ D
Sbjct: 252 GNPFQANKHGERPVDVAETEELELLLKREVPLSDDDESYTDSE-EAQSVNPSSVDENIDS 310
Query: 548 FSSQSASKLKGASLLPGKLPTLVSLF-----DDEDEEDNLF--------------GGTAA 588
+ + + + +LP K P +L DD+DEE N A
Sbjct: 311 ETEKDSLICESKQILPSKTPLPSALDEYEFKDDDDEEINKMIDDRHILRKEQRKENEPEA 370
Query: 589 KKQTLCLQAQREEKAKASELSKKKASALLFSS----DEEDQWNIPASQTHLA------SD 638
+K L + ++ K+ + K+K S +L+SS DEE N S + SD
Sbjct: 371 EKTHLFAKQEKAFYPKSFKSKKQKPSRVLYSSTESSDEEALQNKKISTSCSVIPETSNSD 430
Query: 639 SRSKGEPRDSGTLQSQEAKAVKKTSLFEEDEEDDLFAIAKDSQKKTQRVSLLFEDDVDSG 698
++K E SG Q+ K +K +++E+ K+ ++ T+ +L +D
Sbjct: 431 MQTKKEYVVSGE-HKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRITNLTVNTGLDCS 489
Query: 699 GSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRT 758
T+++ ++ FS +++ L S K + + + T
Sbjct: 490 EK------------TREEGNFRKS----FSPKDDTSLHLFHISTGKSPKHSCGLSEKQST 533
Query: 759 DVAESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQ 818
+ + + L+ + E DL + + P + +V S +E+ K + ++
Sbjct: 534 PLKQEHTKTCLSPGSSEMSLQPDLVRYDNT-ESEFLPESSSVKSCKHKEKSKHQKDFHLE 592
Query: 819 APQKEVGKGRDPDAHPKSTG-------VFQDEELLFSHKLQ----------KDNDPDVDL 861
+K K +D D P + ++ + L HKL+ K+ + + +
Sbjct: 593 FGEKSNAKIKDEDHSPTFENSDCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEK 652
Query: 862 FAGTKKTKLLEPSVG--------SLFGDDEDDDLFSSAKSQPLVQEKKRVVKKDHSVDSF 913
+ K L+ SV + F DE +DLF + + + L EKK ++K+ D
Sbjct: 653 YKTKDSAKELQRSVEFDREFWKENFFKSDETEDLFLNMEHESLTLEKKSKLEKNIKDDKS 712
Query: 914 KNQKHPESIQGSKEK 928
+KH + KE+
Sbjct: 713 TKEKHVSKERNFKEE 727
>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
Length = 2062
Score = 49.7 bits (117), Expect = 2e-05
Identities = 99/495 (20%), Positives = 192/495 (38%), Gaps = 73/495 (14%)
Query: 488 GDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSDEEDSEDL 547
G+ F+ V++T+E + +++V LS SE + Q S +++ D
Sbjct: 275 GNPFQANKHGERPVDVAETEELELLLKREVPLSDDDESYTDSE-EAQSVNPSSVDENIDS 333
Query: 548 FSSQSASKLKGASLLPGKLPTLVSLF-----DDEDEEDNLF--------------GGTAA 588
+ + + + +LP K P +L DD+DEE N A
Sbjct: 334 ETEKDSLICESKQILPSKTPLPSALDEYEFKDDDDEEINKMIDDRHILRKEQRKENEPEA 393
Query: 589 KKQTLCLQAQREEKAKASELSKKKASALLFSS----DEEDQWNIPASQTHLA------SD 638
+K L + ++ K+ + K+K S +L+SS DEE N S + SD
Sbjct: 394 EKTHLFAKQEKAFYPKSFKSKKQKPSRVLYSSTESSDEEALQNKKISTSCSVIPETSNSD 453
Query: 639 SRSKGEPRDSGTLQSQEAKAVKKTSLFEEDEEDDLFAIAKDSQKKTQRVSLLFEDDVDSG 698
++K E SG Q+ K +K +++E+ K+ ++ T+ +L +D
Sbjct: 454 MQTKKEYVVSGE-HKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRITNLTVNTGLDCS 512
Query: 699 GSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRT 758
T+++ ++ FS +++ L S K + + + T
Sbjct: 513 EK------------TREEGNFRKS----FSPKDDTSLHLFHISTGKSPKHSCGLSEKQST 556
Query: 759 DVAESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQ 818
+ + + L+ + E DL + + P + +V S +E+ K + ++
Sbjct: 557 PLKQEHTKTCLSPGSSEMSLQPDLVRYDNT-ESEFLPESSSVKSCKHKEKSKHQKDFHLE 615
Query: 819 APQKEVGKGRDPDAHPKSTG-------VFQDEELLFSHKLQ----------KDNDPDVDL 861
+K K +D D P + ++ + L HKL+ K+ + + +
Sbjct: 616 FGEKSNAKIKDEDHSPTFENSDCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEK 675
Query: 862 FAGTKKTKLLEPSVG--------SLFGDDEDDDLFSSAKSQPLVQEKKRVVKKDHSVDSF 913
+ K L+ SV + F DE +DLF + + + L EKK ++K+ D
Sbjct: 676 YKTKDSAKELQRSVEFDREFWKENFFKSDETEDLFLNMEHESLTLEKKSKLEKNIKDDKS 735
Query: 914 KNQKHPESIQGSKEK 928
+KH + KE+
Sbjct: 736 TKEKHVSKERNFKEE 750
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 49.3 bits (116), Expect = 2e-05
Identities = 118/611 (19%), Positives = 188/611 (30%), Gaps = 122/611 (19%)
Query: 263 ADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRKT 322
A + D ED E + P A A R+ LP G+A + +
Sbjct: 78 AKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVG-------------LPPGKAAAKAS 124
Query: 323 LKEKKERRTPSDDEEDN---------------LFAPPK----------LTDEDFSPFGS- 356
E + DDEED APPK + ED P
Sbjct: 125 ESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQK 184
Query: 357 --------------------GGGLFSGGKGLFDDEDEESDLFTEAPQDRQAGASVKEESS 396
+ GK S ++ ++ +A A+ K+
Sbjct: 185 PKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVP 244
Query: 397 SSKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEPQKP--EQPTPRKS---PYGPPP---- 447
+ K P A + + +S +E +KP +P P S P PPP
Sbjct: 245 KKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSL 304
Query: 448 ------------TGLFDDDDGDDDDDFFSAPHSKP------SKTGKVQSTADIFGDEEGD 489
+ +D D+ D S KP SK A + D
Sbjct: 305 GTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSD 364
Query: 490 LFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKG-------LFSDEE 542
+ EA K + K + S +KP++ K G +D
Sbjct: 365 SSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSS 424
Query: 543 DSEDLFSSQSASK-------------LKGASLLPGKLPTLVSLFDDEDEEDNLFGGTAAK 589
SE+ SS K K A LP K S D + D+ +
Sbjct: 425 SSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSR-DSSSDSDSSSSEEEEE 483
Query: 590 KQTLCLQAQREEKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPR--- 646
K + ++ +K K ASA ++ + + S + KG PR
Sbjct: 484 KTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQA 543
Query: 647 ----DSGTLQSQEAKAVKKTSLFEEDEEDDLFAIAKD-SQKKTQRVSLLFEDDVDSGGSL 701
+ L +Q KA K + EE+++ ++K S KK ++ E + +
Sbjct: 544 PKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQAKKI 603
Query: 702 FGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKK-------VESAKESLK 754
P + P K ++ S + +E E ++++ S D K E A + LK
Sbjct: 604 KLQTPNTFPKRKKGEKRASSPFRRVREEEIEVDSRVADNSFDAKRGAAGDWGERANQVLK 663
Query: 755 FGRTDVAESEK 765
F + EK
Sbjct: 664 FTKGKSFRHEK 674
Score = 46.2 bits (108), Expect = 2e-04
Identities = 123/604 (20%), Positives = 222/604 (36%), Gaps = 116/604 (19%)
Query: 473 TGKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETK 532
TG Q A+ + F K+ PE + +A+KK + S S++ SSE
Sbjct: 38 TGATQQDANASSLLDIYSFWLKSAKVPERKLQANGPVAKKAKKKASSSDSED---SSE-- 92
Query: 533 TQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLPTLVS-------LFDDEDEEDNLFGG 585
+EE+ + + ++A K L PGK S DD+DEED
Sbjct: 93 -------EEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEESSDDDDEEDQ---- 141
Query: 586 TAAKKQTLCLQAQREEKAKASELSKKKASALLFSSDEEDQWNIPASQ----THLASDSRS 641
KKQ +Q + +AKA++ KKA + SD + P +Q T + +++
Sbjct: 142 ---KKQP--VQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQT 196
Query: 642 KGEPRDSGTL-------QSQEAKAVKKTSLFEEDEEDDLFAIAKDSQKKTQRVSLLFEDD 694
K P+ + + + + +S ++ EE+ A K + K Q V+
Sbjct: 197 KAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVA------ 250
Query: 695 VDSGGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESA----- 749
+P + T+K + ++ S +EE+E + +K+ S
Sbjct: 251 --------KAPVKAATTPTRKSSSSEDS-----SSDEEEEQKKPMKNKPGPYSSVPPPSA 297
Query: 750 ---KESLKFGRTDVAESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDE 806
K+SL G ++ ++ S++++ SD SSS +K KP TK V+S
Sbjct: 298 PPPKKSL--GTQPPKKAVEKQQPVESSEDSSDESD---SSSEEEK--KPPTKAVVSKATT 350
Query: 807 EEDKMEDQNIIQAPQKEVGKGRDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTK 866
+ + + + D +A K G ++ N P V T
Sbjct: 351 KPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKN----------SSNKPAV-----TT 395
Query: 867 KTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEKKRVVKKDHSVDSFKNQKHPESIQGSK 926
K+ ++P ++A QP+ +K + +K S S + E + K
Sbjct: 396 KSPAVKP---------------AAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKK 440
Query: 927 EKGIWKPETPQDSSGLAPFKTKEPSTRIGKIQANLAINPAALLPTAASQISEVKPVLPEL 986
KP+ ++ P K +R ++ + + T+ S + + +
Sbjct: 441 MVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGG 500
Query: 987 AFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQTRAAR 1046
A PS P G+A S + +D + ++K +G RPQ A
Sbjct: 501 AAPSK-----------PASAKKGKAESSNS--SSSDDSSEEEEEKLKGKGSPRPQAPKAN 547
Query: 1047 RLAA 1050
+A
Sbjct: 548 GTSA 551
Score = 35.8 bits (81), Expect = 0.28
Identities = 71/316 (22%), Positives = 114/316 (36%), Gaps = 27/316 (8%)
Query: 901 KRVVKKDHSVDSFKNQKHPESIQGSKEKGIWKPETPQDSSGLAPFKTKEPSTRIGKIQAN 960
K+ KK S DS + + E +QG K K P GL P K ++ + +
Sbjct: 76 KKAKKKASSSDSEDSSEEEEEVQGPPAK---KAAVPAKRVGLPPGKAAAKASESSSSEES 132
Query: 961 LAINPAALLPTAASQISEVKPVLPELAFPSSEHRRSHGLE--SVPVLPGSGEAGVSFDLP 1018
+ Q VKP P + + S S P + +
Sbjct: 133 SDDDDEEDQKKQPVQ-KGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVT 191
Query: 1019 AQADTLHSANKSRVKMR---GKRRPQTRAARRLAAQESSETEDMSV-PRGPIAQWADGAI 1074
+A T +R + GK + ++ ++ + SE E + P+ + + A
Sbjct: 192 VKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAK 251
Query: 1075 SP--NGHRPQLRAASGEDSTEEALAAAAAPWEGGP-----VPGVDRSPFAKSLGHSRGEA 1127
+P P +++S EDS+ + P + P VP P KSLG +
Sbjct: 252 APVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKK 311
Query: 1128 DL-----FDSGDIFSTGTGSQSVERTKP--KAKIAENPANPPVGGKAKSPMFPALGEASS 1180
+ +S + S + S S E KP KA +++ PP KA + SS
Sbjct: 312 AVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSS 371
Query: 1181 DDDLFQSAKPKPAKKT 1196
+DD A KPA T
Sbjct: 372 EDD---EAPSKPAGTT 384
Score = 31.2 bits (69), Expect = 7.0
Identities = 34/135 (25%), Positives = 51/135 (37%), Gaps = 21/135 (15%)
Query: 1064 GPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAAAAPWEGGPVPGVDRSPFAKSLGHS 1123
GP+A+ A + + ++ EDS+EE P + VP AK +G
Sbjct: 72 GPVAKKA---------KKKASSSDSEDSSEEEEEVQGPPAKKAAVP-------AKRVGLP 115
Query: 1124 RGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANPPVGGKAKSPMFPALGEASSDDD 1183
G+A S S + E + K P V +AK+ P SSD D
Sbjct: 116 PGKAAAKASESSSSEESSDDDDEEDQKK-----QPVQKGVKPQAKAAKAPPKKAKSSDSD 170
Query: 1184 LFQSAKPKPAKKTNP 1198
S++ +P K P
Sbjct: 171 SDSSSEDEPPKNQKP 185
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 48.9 bits (115), Expect = 3e-05
Identities = 183/853 (21%), Positives = 318/853 (37%), Gaps = 118/853 (13%)
Query: 486 EEGDLFKEKAVAS------PEATVSQTDENKARAEKKVTLSSSKNLKPSSETKT---QKG 536
EE L K+KA A PE +E K R+E+K L K KP+ E K +
Sbjct: 1196 EESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEK--KPTPEDKKLLPEAK 1253
Query: 537 LFSDEEDSEDLFSSQ---SASKLKG----ASLLPGKLP----------TLVSLFDDEDEE 579
+ EE DL SQ + KL+G ++ GK P T SL +E
Sbjct: 1254 TSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSL----PKE 1309
Query: 580 DNLFGGTAAKKQTLCLQAQREEKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASD- 638
D+ T ++ A+ ++ E ++K+ SS ++ + S T +SD
Sbjct: 1310 DDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDG 1369
Query: 639 -SRSKGE-PRDSGTLQSQEAKAVKKTSLFEEDEEDDLFAIAKDSQKKTQRVSLLFEDDVD 696
S S GE P T + K +KK S +E +AK + D
Sbjct: 1370 ISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLAD 1429
Query: 697 SGGSLFGSPPTSVPPATK---KKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKESL 753
P P K K +++SE + S+EE KE+Q K KK +++ +
Sbjct: 1430 EKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKK--DSQQDI 1487
Query: 754 KFGRTDVAESEKEGLLT--RSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDE----- 806
+ +SE +T R ++V+ S S +SP + K RT S DE
Sbjct: 1488 PSSKDHKEKSEFVDDITTRREPYDSVEESS-ESENSPVPQ-RKRRTSVGSSSSDEYKQED 1545
Query: 807 -----EEDKMEDQNIIQAPQKEVGKGRDPDAHPKSTGVFQDEELLFSHKLQ-KDNDPDVD 860
EE+ + II+ E G + D ++ Q +E+ S + Q K+
Sbjct: 1546 SQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRN----QLKEISSSTESQKKEETKGKG 1601
Query: 861 LFAGTKKTKLLEPSVGSLFGD--------DEDDDLF-----------SSAKSQPLVQEKK 901
K +L S S+ D DEDD+ F S +S+ LV
Sbjct: 1602 KITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRETKSQESEELVVTGG 1661
Query: 902 RVVKKDHSVDSFKNQKHPESIQGSKEK-GIWKPETPQDSSGLAPFKTKEPSTRIGKIQAN 960
+++ +++ S + S++K ++ E P+ ++ S G +
Sbjct: 1662 GGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLH 1721
Query: 961 LAINPAALLPTAASQISEVKPVLP-ELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPA 1019
+ PT+ S + E P S + R++ P+LP ++ +L
Sbjct: 1722 ASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSEEEELRE 1781
Query: 1020 QADTLHSANKSRVKMRGKRRPQTRAARR----LAAQESSETEDMSVPRGPIAQWADGAIS 1075
+ + L K R + +R+ ++ +++ L AQ E P+ P + + I
Sbjct: 1782 EEELLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQRRRER-----PKTPPSNLS--PIE 1834
Query: 1076 PNGHRPQLRAASGEDSTEEALAAAAAPWEGGPVPGVDRSPFAKSLGHSRGEADLFDSGDI 1135
+LR A+ + + + +P G + SP + + + L + +
Sbjct: 1835 DASPTEELRQAAEMEELHRSSCSEYSPSIESDPEGFEISP--EKIIEVQKVYKLPTAVSL 1892
Query: 1136 FSTGTGSQSV---ERTKPKAKIAENPANPPVGGKAKSPMFPALGEASSDDDLFQSAKPKP 1192
+S T QS+ E ++ K AE + K FPA A+ D++F+
Sbjct: 1893 YSP-TDEQSIMQKEGSQKALKSAEEMYEEMMHKTHKYKAFPA---ANERDEVFEKEPLYG 1948
Query: 1193 AKKTNPF---PLLED------EDDLFTDQKVKKNETKSNSQQDVILTTQDIFEDDIFATE 1243
+ L+ED + L T Q+ + + ++ I ++ I+ED
Sbjct: 1949 GMLIEDYIYESLVEDTYNGSVDGSLLTRQEEENGFMQQKGREQKIRLSEQIYED------ 2002
Query: 1244 AIKPSQKTREKEK 1256
P QK + +K
Sbjct: 2003 ---PMQKITDLQK 2012
Score = 47.8 bits (112), Expect = 7e-05
Identities = 108/554 (19%), Positives = 214/554 (38%), Gaps = 86/554 (15%)
Query: 222 EEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGC-----DLFADSEKEEEDI-EDI 275
E KE+ E ++D + S ++Q + +SD DG ++ + +E+DI + +
Sbjct: 1333 EPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGL 1392
Query: 276 EENTRPKRSRPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDD 335
++++ + S P+S +D A+++ + ++ + +TL + E +KT + P D
Sbjct: 1393 KKDSFSQESSPSSPSD--LAKLESTVLSILEAQASTL-ADEKSEKKTQPHEVSPEQPKDQ 1449
Query: 336 EE-DNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLF-TEAPQDRQAGASVKE 393
E+ +L ++T + + + + ++E D F ++ QD + KE
Sbjct: 1450 EKTQSLSETLEITISE--------------EEIKESQEERKDTFKKDSQQDIPSSKDHKE 1495
Query: 394 ESS--SSKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEPQKPEQPTPRKSPYGPPPTGLF 451
+S ++ P +V S + P R++ G + +
Sbjct: 1496 KSEFVDDITTRREPYDSVE--------------ESSESENSPVPQRKRRTSVGSSSSDEY 1541
Query: 452 DDDDGD---DDDDFFSAPHSKPSKTGKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDE 508
+D +++DF + ++ + D G E+ + + + +T SQ E
Sbjct: 1542 KQEDSQGSGEEEDFIR------KQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKKE 1595
Query: 509 NKARAEKKVTLSSSKNLKPSSETKTQKGL---FSDEEDSEDLFSSQSASKLKGASLLPGK 565
+ + + K+T + L S T + S ++ ++ F K +
Sbjct: 1596 -ETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRETK----- 1649
Query: 566 LPTLVSLFDDEDEEDNLFGGTAAKK-QTLCLQAQREEKAKASELSKKKASALLFSSDEED 624
E EE + GG ++ +T+ L + +K A E S+KK S DEE
Sbjct: 1650 --------SQESEELVVTGGGGLRRFKTIELNSTIADKYSA-ESSQKKTSLYF---DEEP 1697
Query: 625 QWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDEEDDLFAIAKDSQKKT 684
+ + + + + RS+GE S S TS+ DE+ D K + K
Sbjct: 1698 ELEMESLTD--SPEDRSRGE-GSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQ 1754
Query: 685 QRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKE-AQLGVKSVD 743
QR P + ++E + E LL E+++E Q KS
Sbjct: 1755 QR----------KARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSS 1804
Query: 744 KKVESAKESLKFGR 757
KK + K+ L+ R
Sbjct: 1805 KKSKKDKDELRAQR 1818
Score = 45.8 bits (107), Expect = 3e-04
Identities = 175/866 (20%), Positives = 306/866 (35%), Gaps = 199/866 (22%)
Query: 105 EEPVLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDD 164
+E +K EAEK EK +E ++ IP + D K S E+D
Sbjct: 1160 QEQEVKTEAEKVILEKVKETLSMEKIPPMVTT---------------DQKQEESKLEKDK 1204
Query: 165 ANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEE 224
A+ E +PLP KL E+E ++ SEE + +++ ++
Sbjct: 1205 ASALQE----------KKPLPE--EKKLIPEEE-----KIRSEE------KKPLLEEKKP 1241
Query: 225 KEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRS 284
E++ A S E+ +H DL + E E +E PK
Sbjct: 1242 TPEDKKLLPEAKTSAPEEQKH--------------DLLKSQVQIAE--EKLEGRVAPKTV 1285
Query: 285 RPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPP 344
+ + +++G G P +LP + K KT+KE+ + PP
Sbjct: 1286 QE---GKQPQTKMEGLPSGT----PQSLPKEDDKTTKTIKEQPQ--------------PP 1324
Query: 345 KLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEAPQDRQAGASVKEESSSSKPGKKI 404
D GK + ED++SD T + Q ++ + + SS
Sbjct: 1325 CTAKPD---------QVEPGKEKTEKEDDKSD--TSSSQQPKSPQGLSDTGYSSD----- 1368
Query: 405 PAGAVSVFLGDTDVFGAASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFS 464
+S LG+ +PS+ PT K GL D + S
Sbjct: 1369 ---GISSSLGE--------IPSLI-------PTDEKDIL----KGLKKDSFSQE-----S 1401
Query: 465 APHSKPSKTGKVQST--------ADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKK 516
+P S PS K++ST A DE+ + + SPE Q EK
Sbjct: 1402 SP-SSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQ--------EKT 1452
Query: 517 VTLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLPTLVSLFDDE 576
+LS + + S E + +E+ +D F S + + D +
Sbjct: 1453 QSLSETLEITISEEE-----IKESQEERKDTFKKDSQQDIPSSK-------------DHK 1494
Query: 577 DEEDNLFGGTAAKKQTLCLQAQREEKAKASELSKKKASALLFSSDEEDQWNIPASQTHLA 636
++ + + T ++ ++ E + K++ S SSDE Q
Sbjct: 1495 EKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQ----------- 1543
Query: 637 SDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDE--EDDLFAIAK--DSQKKTQRVSLLFE 692
DS+ GE D Q E A + S E+DE + L I+ +SQKK
Sbjct: 1544 EDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKK--------- 1594
Query: 693 DDVDSGGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKES 752
++ G + + T+K T S +E+ + D +
Sbjct: 1595 EETKGKGKITAGKHRRL---TRKSST---------SIDEDAGRRHSWHDEDDEAFDESPE 1642
Query: 753 LKFGRTDVAESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKME 812
LK+ T ESE+ + K +L S+ + DK + ++ SL+ +EE ++E
Sbjct: 1643 LKYRETKSQESEELVVTGGGGLRRFKTIELNSTIA--DKYSAESSQKKTSLYFDEEPELE 1700
Query: 813 DQNIIQAPQKEVGKGRDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLE 872
+++ +P+ H S + S D+ P ++ K
Sbjct: 1701 MESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARH 1760
Query: 873 PSVGSLFGDDEDDDLFSSAKSQPLV---QEKKR-VVKKDHSVDSFKNQKHPESIQGSKEK 928
G L ED + + + QEK+R + ++ S K++K + ++ + +
Sbjct: 1761 RPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQRRR 1820
Query: 929 GIWKPETPQDSSGLAPFKTKEPSTRI 954
+P+TP S L+P + P+ +
Sbjct: 1821 E--RPKTP--PSNLSPIEDASPTEEL 1842
Score = 32.0 bits (71), Expect = 4.1
Identities = 56/283 (19%), Positives = 102/283 (36%), Gaps = 33/283 (11%)
Query: 421 AASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTA 480
AA + + K P+ S + P + D + D+ S S S G + S A
Sbjct: 4181 AAILYQKQSKHKKSLIDPKMSKFSPI------QESRDLEPDYSSYMTSSTSSIGGISSRA 4234
Query: 481 DIFGDE----------EGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSE 530
+ D+ + F ++ + T+ T + + E SS +PSS
Sbjct: 4235 RLLQDDITFGLRKNITDQQKFMGSSLGTGLGTLGNTIRSALQDEADKPYSSGSRSRPSSR 4294
Query: 531 TKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLPTLVSLFDDEDEEDNLFGGTAAKK 590
+ GL D D SS K + A L S + + + ++
Sbjct: 4295 PSSVYGL--DLSIKRDSSSSSLRLKAQEAEALDVSFSHASSSARTKPTSLPI---SQSRG 4349
Query: 591 QTLCLQAQREEKAKASELSKKKASALL-------FSSDEEDQW----NIPASQTHLASDS 639
+ + EE++ S + + A S+D DQ+ ++P Q H+ +S
Sbjct: 4350 RIPIVAQNSEEESPLSPVGQPMGMARAAAGPLPPISADTRDQFGSSHSLPEVQQHMREES 4409
Query: 640 RSKGEPRDSGTLQSQEAKAVKKTSLFE-EDEEDDLFAIAKDSQ 681
R++G RD + A+ + + EE D F ++S+
Sbjct: 4410 RTRGYDRDIAFIMDDFQHAMSDSEAYHLRREETDWFDKPRESR 4452
Score = 30.8 bits (68), Expect = 9.1
Identities = 59/343 (17%), Positives = 129/343 (37%), Gaps = 49/343 (14%)
Query: 211 VGSDRGSIVDTEEEKEEEESD--EDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFADSEK- 267
VG + ++ EE+K++++ D + +Q R ++ E ++ F + EK
Sbjct: 3195 VGDESALLIVPEEDKQQQQLDLERELLELEKIKQQRFAEELEWERQE---IQRFREQEKI 3251
Query: 268 ----EEEDIEDIEENT--RPKRSRPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRK 321
+ E+++ ++++ + + R F ++ + + + + + + + +
Sbjct: 3252 MVQKKLEELQSMKQHLLFQQEEERQAQFM------MRQETLAQQQLQLEQIQQLQQQLHQ 3305
Query: 322 TLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEA 381
L+E+K R+ + + + A P+ T E G L E S +
Sbjct: 3306 QLEEQKIRQIYQYNYDPSGTASPQTTTEQAILEGQYAAL------------EGSQFWATE 3353
Query: 382 PQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEPQKPEQPTPRKS 441
A A V E S+ + + V+ ++ + S + + E+ P+K
Sbjct: 3354 DATTTASAVVAIEIPQSQGWYTVQSDGVTQYIAPPGILSTVSEIPLTDVVVKEEKQPKKR 3413
Query: 442 PYGPPPTGLFDD----------------DDG---DDDDDFFSAPHSKPSKTGKVQSTADI 482
G G +DD D G DD+D + S+ +T K T+
Sbjct: 3414 SSGAKVRGQYDDMGENMTDDPRSFKKIVDSGVQTDDEDATDRSYVSRRRRTKKSVDTSVQ 3473
Query: 483 FGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNL 525
DE+ D + + +A V + ++ A+K LS ++
Sbjct: 3474 TDDEDQDEWDMPTRSRRKARVGKYGDSMTEADKTKPLSKVSSI 3516
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 48.9 bits (115), Expect = 3e-05
Identities = 183/853 (21%), Positives = 318/853 (37%), Gaps = 118/853 (13%)
Query: 486 EEGDLFKEKAVAS------PEATVSQTDENKARAEKKVTLSSSKNLKPSSETKT---QKG 536
EE L K+KA A PE +E K R+E+K L K KP+ E K +
Sbjct: 1196 EESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEK--KPTPEDKKLLPEAK 1253
Query: 537 LFSDEEDSEDLFSSQ---SASKLKG----ASLLPGKLP----------TLVSLFDDEDEE 579
+ EE DL SQ + KL+G ++ GK P T SL +E
Sbjct: 1254 TSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSL----PKE 1309
Query: 580 DNLFGGTAAKKQTLCLQAQREEKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASD- 638
D+ T ++ A+ ++ E ++K+ SS ++ + S T +SD
Sbjct: 1310 DDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDG 1369
Query: 639 -SRSKGE-PRDSGTLQSQEAKAVKKTSLFEEDEEDDLFAIAKDSQKKTQRVSLLFEDDVD 696
S S GE P T + K +KK S +E +AK + D
Sbjct: 1370 ISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLAD 1429
Query: 697 SGGSLFGSPPTSVPPATK---KKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKESL 753
P P K K +++SE + S+EE KE+Q K KK +++ +
Sbjct: 1430 EKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKK--DSQQDI 1487
Query: 754 KFGRTDVAESEKEGLLT--RSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDE----- 806
+ +SE +T R ++V+ S S +SP + K RT S DE
Sbjct: 1488 PSSKDHKEKSEFVDDITTRREPYDSVEESS-ESENSPVPQ-RKRRTSVGSSSSDEYKQED 1545
Query: 807 -----EEDKMEDQNIIQAPQKEVGKGRDPDAHPKSTGVFQDEELLFSHKLQ-KDNDPDVD 860
EE+ + II+ E G + D ++ Q +E+ S + Q K+
Sbjct: 1546 SQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRN----QLKEISSSTESQKKEETKGKG 1601
Query: 861 LFAGTKKTKLLEPSVGSLFGD--------DEDDDLF-----------SSAKSQPLVQEKK 901
K +L S S+ D DEDD+ F S +S+ LV
Sbjct: 1602 KITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRETKSQESEELVVTGG 1661
Query: 902 RVVKKDHSVDSFKNQKHPESIQGSKEK-GIWKPETPQDSSGLAPFKTKEPSTRIGKIQAN 960
+++ +++ S + S++K ++ E P+ ++ S G +
Sbjct: 1662 GGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLH 1721
Query: 961 LAINPAALLPTAASQISEVKPVLP-ELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPA 1019
+ PT+ S + E P S + R++ P+LP ++ +L
Sbjct: 1722 ASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSEEEELRE 1781
Query: 1020 QADTLHSANKSRVKMRGKRRPQTRAARR----LAAQESSETEDMSVPRGPIAQWADGAIS 1075
+ + L K R + +R+ ++ +++ L AQ E P+ P + + I
Sbjct: 1782 EEELLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQRRRER-----PKTPPSNLS--PIE 1834
Query: 1076 PNGHRPQLRAASGEDSTEEALAAAAAPWEGGPVPGVDRSPFAKSLGHSRGEADLFDSGDI 1135
+LR A+ + + + +P G + SP + + + L + +
Sbjct: 1835 DASPTEELRQAAEMEELHRSSCSEYSPSIESDPEGFEISP--EKIIEVQKVYKLPTAVSL 1892
Query: 1136 FSTGTGSQSV---ERTKPKAKIAENPANPPVGGKAKSPMFPALGEASSDDDLFQSAKPKP 1192
+S T QS+ E ++ K AE + K FPA A+ D++F+
Sbjct: 1893 YSP-TDEQSIMQKEGSQKALKSAEEMYEEMMHKTHKYKAFPA---ANERDEVFEKEPLYG 1948
Query: 1193 AKKTNPF---PLLED------EDDLFTDQKVKKNETKSNSQQDVILTTQDIFEDDIFATE 1243
+ L+ED + L T Q+ + + ++ I ++ I+ED
Sbjct: 1949 GMLIEDYIYESLVEDTYNGSVDGSLLTRQEEENGFMQQKGREQKIRLSEQIYED------ 2002
Query: 1244 AIKPSQKTREKEK 1256
P QK + +K
Sbjct: 2003 ---PMQKITDLQK 2012
Score = 47.8 bits (112), Expect = 7e-05
Identities = 108/554 (19%), Positives = 214/554 (38%), Gaps = 86/554 (15%)
Query: 222 EEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGC-----DLFADSEKEEEDI-EDI 275
E KE+ E ++D + S ++Q + +SD DG ++ + +E+DI + +
Sbjct: 1333 EPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGL 1392
Query: 276 EENTRPKRSRPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDD 335
++++ + S P+S +D A+++ + ++ + +TL + E +KT + P D
Sbjct: 1393 KKDSFSQESSPSSPSD--LAKLESTVLSILEAQASTL-ADEKSEKKTQPHEVSPEQPKDQ 1449
Query: 336 EE-DNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLF-TEAPQDRQAGASVKE 393
E+ +L ++T + + + + ++E D F ++ QD + KE
Sbjct: 1450 EKTQSLSETLEITISE--------------EEIKESQEERKDTFKKDSQQDIPSSKDHKE 1495
Query: 394 ESS--SSKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEPQKPEQPTPRKSPYGPPPTGLF 451
+S ++ P +V S + P R++ G + +
Sbjct: 1496 KSEFVDDITTRREPYDSVE--------------ESSESENSPVPQRKRRTSVGSSSSDEY 1541
Query: 452 DDDDGD---DDDDFFSAPHSKPSKTGKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDE 508
+D +++DF + ++ + D G E+ + + + +T SQ E
Sbjct: 1542 KQEDSQGSGEEEDFIR------KQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKKE 1595
Query: 509 NKARAEKKVTLSSSKNLKPSSETKTQKGL---FSDEEDSEDLFSSQSASKLKGASLLPGK 565
+ + + K+T + L S T + S ++ ++ F K +
Sbjct: 1596 -ETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRETK----- 1649
Query: 566 LPTLVSLFDDEDEEDNLFGGTAAKK-QTLCLQAQREEKAKASELSKKKASALLFSSDEED 624
E EE + GG ++ +T+ L + +K A E S+KK S DEE
Sbjct: 1650 --------SQESEELVVTGGGGLRRFKTIELNSTIADKYSA-ESSQKKTSLYF---DEEP 1697
Query: 625 QWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDEEDDLFAIAKDSQKKT 684
+ + + + + RS+GE S S TS+ DE+ D K + K
Sbjct: 1698 ELEMESLTD--SPEDRSRGE-GSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQ 1754
Query: 685 QRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKE-AQLGVKSVD 743
QR P + ++E + E LL E+++E Q KS
Sbjct: 1755 QR----------KARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSS 1804
Query: 744 KKVESAKESLKFGR 757
KK + K+ L+ R
Sbjct: 1805 KKSKKDKDELRAQR 1818
Score = 45.8 bits (107), Expect = 3e-04
Identities = 175/866 (20%), Positives = 306/866 (35%), Gaps = 199/866 (22%)
Query: 105 EEPVLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDD 164
+E +K EAEK EK +E ++ IP + D K S E+D
Sbjct: 1160 QEQEVKTEAEKVILEKVKETLSMEKIPPMVTT---------------DQKQEESKLEKDK 1204
Query: 165 ANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEE 224
A+ E +PLP KL E+E ++ SEE + +++ ++
Sbjct: 1205 ASALQE----------KKPLPE--EKKLIPEEE-----KIRSEE------KKPLLEEKKP 1241
Query: 225 KEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRS 284
E++ A S E+ +H DL + E E +E PK
Sbjct: 1242 TPEDKKLLPEAKTSAPEEQKH--------------DLLKSQVQIAE--EKLEGRVAPKTV 1285
Query: 285 RPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPP 344
+ + +++G G P +LP + K KT+KE+ + PP
Sbjct: 1286 QE---GKQPQTKMEGLPSGT----PQSLPKEDDKTTKTIKEQPQ--------------PP 1324
Query: 345 KLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEAPQDRQAGASVKEESSSSKPGKKI 404
D GK + ED++SD T + Q ++ + + SS
Sbjct: 1325 CTAKPD---------QVEPGKEKTEKEDDKSD--TSSSQQPKSPQGLSDTGYSSD----- 1368
Query: 405 PAGAVSVFLGDTDVFGAASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFS 464
+S LG+ +PS+ PT K GL D + S
Sbjct: 1369 ---GISSSLGE--------IPSLI-------PTDEKDIL----KGLKKDSFSQE-----S 1401
Query: 465 APHSKPSKTGKVQST--------ADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKK 516
+P S PS K++ST A DE+ + + SPE Q EK
Sbjct: 1402 SP-SSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQ--------EKT 1452
Query: 517 VTLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLPTLVSLFDDE 576
+LS + + S E + +E+ +D F S + + D +
Sbjct: 1453 QSLSETLEITISEEE-----IKESQEERKDTFKKDSQQDIPSSK-------------DHK 1494
Query: 577 DEEDNLFGGTAAKKQTLCLQAQREEKAKASELSKKKASALLFSSDEEDQWNIPASQTHLA 636
++ + + T ++ ++ E + K++ S SSDE Q
Sbjct: 1495 EKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQ----------- 1543
Query: 637 SDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDE--EDDLFAIAK--DSQKKTQRVSLLFE 692
DS+ GE D Q E A + S E+DE + L I+ +SQKK
Sbjct: 1544 EDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKK--------- 1594
Query: 693 DDVDSGGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKES 752
++ G + + T+K T S +E+ + D +
Sbjct: 1595 EETKGKGKITAGKHRRL---TRKSST---------SIDEDAGRRHSWHDEDDEAFDESPE 1642
Query: 753 LKFGRTDVAESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKME 812
LK+ T ESE+ + K +L S+ + DK + ++ SL+ +EE ++E
Sbjct: 1643 LKYRETKSQESEELVVTGGGGLRRFKTIELNSTIA--DKYSAESSQKKTSLYFDEEPELE 1700
Query: 813 DQNIIQAPQKEVGKGRDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLE 872
+++ +P+ H S + S D+ P ++ K
Sbjct: 1701 MESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARH 1760
Query: 873 PSVGSLFGDDEDDDLFSSAKSQPLV---QEKKR-VVKKDHSVDSFKNQKHPESIQGSKEK 928
G L ED + + + QEK+R + ++ S K++K + ++ + +
Sbjct: 1761 RPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQRRR 1820
Query: 929 GIWKPETPQDSSGLAPFKTKEPSTRI 954
+P+TP S L+P + P+ +
Sbjct: 1821 E--RPKTP--PSNLSPIEDASPTEEL 1842
Score = 32.0 bits (71), Expect = 4.1
Identities = 56/283 (19%), Positives = 102/283 (36%), Gaps = 33/283 (11%)
Query: 421 AASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTA 480
AA + + K P+ S + P + D + D+ S S S G + S A
Sbjct: 4181 AAILYQKQSKHKKSLIDPKMSKFSPI------QESRDLEPDYSSYMTSSTSSIGGISSRA 4234
Query: 481 DIFGDE----------EGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSE 530
+ D+ + F ++ + T+ T + + E SS +PSS
Sbjct: 4235 RLLQDDITFGLRKNITDQQKFMGSSLGTGLGTLGNTIRSALQDEADKPYSSGSRSRPSSR 4294
Query: 531 TKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLPTLVSLFDDEDEEDNLFGGTAAKK 590
+ GL D D SS K + A L S + + + ++
Sbjct: 4295 PSSVYGL--DLSIKRDSSSSSLRLKAQEAEALDVSFSHASSSARTKPTSLPI---SQSRG 4349
Query: 591 QTLCLQAQREEKAKASELSKKKASALL-------FSSDEEDQW----NIPASQTHLASDS 639
+ + EE++ S + + A S+D DQ+ ++P Q H+ +S
Sbjct: 4350 RIPIVAQNSEEESPLSPVGQPMGMARAAAGPLPPISADTRDQFGSSHSLPEVQQHMREES 4409
Query: 640 RSKGEPRDSGTLQSQEAKAVKKTSLFE-EDEEDDLFAIAKDSQ 681
R++G RD + A+ + + EE D F ++S+
Sbjct: 4410 RTRGYDRDIAFIMDDFQHAMSDSEAYHLRREETDWFDKPRESR 4452
Score = 30.8 bits (68), Expect = 9.1
Identities = 59/343 (17%), Positives = 129/343 (37%), Gaps = 49/343 (14%)
Query: 211 VGSDRGSIVDTEEEKEEEESD--EDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFADSEK- 267
VG + ++ EE+K++++ D + +Q R ++ E ++ F + EK
Sbjct: 3195 VGDESALLIVPEEDKQQQQLDLERELLELEKIKQQRFAEELEWERQE---IQRFREQEKI 3251
Query: 268 ----EEEDIEDIEENT--RPKRSRPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRK 321
+ E+++ ++++ + + R F ++ + + + + + + + +
Sbjct: 3252 MVQKKLEELQSMKQHLLFQQEEERQAQFM------MRQETLAQQQLQLEQIQQLQQQLHQ 3305
Query: 322 TLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEA 381
L+E+K R+ + + + A P+ T E G L E S +
Sbjct: 3306 QLEEQKIRQIYQYNYDPSGTASPQTTTEQAILEGQYAAL------------EGSQFWATE 3353
Query: 382 PQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEPQKPEQPTPRKS 441
A A V E S+ + + V+ ++ + S + + E+ P+K
Sbjct: 3354 DATTTASAVVAIEIPQSQGWYTVQSDGVTQYIAPPGILSTVSEIPLTDVVVKEEKQPKKR 3413
Query: 442 PYGPPPTGLFDD----------------DDG---DDDDDFFSAPHSKPSKTGKVQSTADI 482
G G +DD D G DD+D + S+ +T K T+
Sbjct: 3414 SSGAKVRGQYDDMGENMTDDPRSFKKIVDSGVQTDDEDATDRSYVSRRRRTKKSVDTSVQ 3473
Query: 483 FGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNL 525
DE+ D + + +A V + ++ A+K LS ++
Sbjct: 3474 TDDEDQDEWDMPTRSRRKARVGKYGDSMTEADKTKPLSKVSSI 3516
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 48.5 bits (114), Expect = 4e-05
Identities = 139/684 (20%), Positives = 240/684 (35%), Gaps = 118/684 (17%)
Query: 105 EEPVLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDD 164
E+ E K + K +K L K + V GL + F + D S+ ++
Sbjct: 890 EQSFTSLEVRKVAETK---EKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQ 946
Query: 165 ANGRVELILEPKDL---YIDRPLPYLI---GSKLFMEQEDV-----GLGELSSEEGSVGS 213
+ E +P D I Y G++ E+E++ G+ ++ +
Sbjct: 947 SKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEK 1006
Query: 214 DRGSIVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDG--------CDLFADS 265
I D +K++E SD +A S + + + S++++ +G C L S
Sbjct: 1007 KSKKIRDKTSKKKDELSD--YAEKSTGKGD--SCDSSEDKKSKNGAYGREKKRCKLLGKS 1062
Query: 266 EKEEEDIEDIEENTRPKRSRPTSFAD------ELAARIKGDAVGRVDEEPTTLPSGEAKP 319
++ +D + + + +D EL R + E + S +A+
Sbjct: 1063 SRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEE 1122
Query: 320 RKTLKEKKERRTPS--------DDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDE 371
+KK++RT S + + ++L K D + S D E
Sbjct: 1123 SSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSS-----------DIE 1171
Query: 372 DEESDLFTEAPQDRQAGASVKEESSSSK-------PGKKIPAGAVSVFLGDTDVFGAASV 424
D++ + E D Q V E S G + + +V V + D D
Sbjct: 1172 DDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDD------- 1224
Query: 425 PSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFG 484
+ PE +K L D+DG DD+ P +TGK G
Sbjct: 1225 ----DDNDPENRIAKKMLLEEIKANLSSDEDGSSDDE----PEEGKKRTGKQNEENP--G 1274
Query: 485 DEEGDLFKEKAVASPEATVSQTDENKAR-----AEKKVTLSSS-----KNLKPSS--ETK 532
DEE K + E+ + K R K+T+S K KP E K
Sbjct: 1275 DEEA-----KNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVK 1329
Query: 533 TQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLPTLVSLFDDEDEEDNLFGGTAAKKQT 592
+ EDSED +S + + + P S E EE+ K++
Sbjct: 1330 GRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRR 1389
Query: 593 LCLQ--AQREEKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGT 650
+ +Q + E K+ + E ++K +EE++ + S S KG +
Sbjct: 1390 IKVQEDSSSENKSNSEEEEEEKEE----EEEEEEEEEEEEEDENDDSKSPGKGRKKIRKI 1445
Query: 651 LQSQEAKAVKKTSLFEEDEEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVP 710
L+ + + + +L EE+E A + ++K + V + ED + PT P
Sbjct: 1446 LKDDKLRTETQNALKEEEERRKRIAEREREREKLREV-IEIED----------ASPTKCP 1494
Query: 711 PATKKKETVSEAPPLLFSDEEEKE 734
TK +L DEE KE
Sbjct: 1495 ITTKL---------VLDEDEETKE 1509
Score = 43.9 bits (102), Expect = 0.001
Identities = 183/926 (19%), Positives = 331/926 (35%), Gaps = 129/926 (13%)
Query: 423 SVPSMKEPQKP------EQPTPRKSPYGPPPTGLFDDDDGDDD----DDFFSAPHSKPSK 472
SVP K+ ++ + P P K P + + D D+ + HS S
Sbjct: 654 SVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVSRMSHSSSSD 713
Query: 473 T--GKVQSTADIFGD---EEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKP 527
T ++ + D + G K K + S D K ++ K +S K
Sbjct: 714 TDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKR--- 770
Query: 528 SSETKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLPTLVSLFDDEDEEDNLFGGTA 587
+T+++ + E + E +S SK+ A ++P EDE+ + G
Sbjct: 771 --QTQSESSNYDSELEKE----IKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDN 824
Query: 588 AKKQTLCLQAQREEKAKASELSKKKASALLFSSDE----------EDQWNIPASQTHLAS 637
+ L + + +S+ +++K FSS E E + +P Q AS
Sbjct: 825 QGHKNL-----KTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASAS 879
Query: 638 DSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDE-----------EDDLFAIAKDSQKKTQR 686
+ G + SG QS + V+K + +E +D L IA+ KK Q
Sbjct: 880 ---TDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQS 936
Query: 687 VSLLFEDDVDSGGSLFGSPPTSVPPATKKK--------ETVSEAPPLLFSDEEEKEAQLG 738
+ D S G+ P KKK E+ S+ L EE G
Sbjct: 937 DE---TSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKG 993
Query: 739 VKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHSDLFSSSSPWDK-GTKPRT 797
+K + ++ K R D +K+ L + + T K SS K G R
Sbjct: 994 IKQIKNGTTDGEKKSKKIR-DKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGRE 1052
Query: 798 KTVLSLFDEEEDKMEDQNIIQAPQKEVGKGRDPDAHPKSTGVFQDEELLFSHKLQKDNDP 857
K L + K +D + + + K G ++ L +L++ +
Sbjct: 1053 KKRCKLLGKSSRKRQDCSSSDTEKYSM----------KEDGCNSSDKRLKRIELRERRN- 1101
Query: 858 DVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEKKRVVKKDHSVDSFKNQK 917
+ + TK E GS D E+ + K Q +KK V+ K+ +S +
Sbjct: 1102 ----LSSKRNTK--EIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTST 1155
Query: 918 HPESIQGSKEKGIWKPETPQDSSGLAPFKTKEPSTRIGKIQANLAINPAALLPTAASQIS 977
+ + + Q+S G + +I + NL ++ ++ +
Sbjct: 1156 KRKQADITSSSSSDIEDDDQNSIG----EGSSDEQKIKPVTENLVLSSHTGFCQSSGDEA 1211
Query: 978 EVKPVLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGK 1037
K V P + + +L +A +S D +D K R + +
Sbjct: 1212 LSKSV-PVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNE 1270
Query: 1038 RRPQTRAARRLAAQES-SETEDMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEAL 1096
P A+ ES S++E+ PR R +L + GE E+
Sbjct: 1271 ENPGDEEAKNQVNSESDSDSEESKKPR----------YRHRLLRHKLTVSDGESGEEK-- 1318
Query: 1097 AAAAAPWEGGPVPGVDRSPFAKSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPK---AK 1153
P E V G +R K ++D +SG + S+S + +P+ AK
Sbjct: 1319 --KTKPKEHKEVKGRNR---RKVSSEDSEDSDFQESG---VSEEVSESEDEQRPRTRSAK 1370
Query: 1154 IAENPANPPVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFPLLEDEDDLFTDQK 1213
AE N + K + E SS ++ S + + K+ E+E++ +++
Sbjct: 1371 KAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEE----EEEEEEEEEEE 1426
Query: 1214 VKKNETKSNSQQDVILTTQDIFEDDIFATE---AIKPSQKTREK--EKTLESNLFDDNID 1268
+ +++KS + + + I +DD TE A+K ++ R++ E+ E + I+
Sbjct: 1427 DENDDSKSPGKGRKKI--RKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIE 1484
Query: 1269 IFADLTVKPKEKSKKKVEAKSIFDDD 1294
I + +K + K + D+D
Sbjct: 1485 I------EDASPTKCPITTKLVLDED 1504
Score = 30.8 bits (68), Expect = 9.1
Identities = 27/127 (21%), Positives = 51/127 (40%), Gaps = 10/127 (7%)
Query: 207 EEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFADSE 266
+E S ++ + + EEEKEEEE +E+ + ++N D + G
Sbjct: 1393 QEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDEN------DDSKSPGKGRKKIRKIL 1446
Query: 267 KEEEDIEDIEENTRPKRSRPTSFADELAARIK-GDAVGRVDEEPTTLPSGEAKPRKTLKE 325
K+++ + + + + R A+ R K + + D PT P + L E
Sbjct: 1447 KDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIEDASPTKCP---ITTKLVLDE 1503
Query: 326 KKERRTP 332
+E + P
Sbjct: 1504 DEETKEP 1510
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.306 0.126 0.348
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 56,730,318
Number of Sequences: 37866
Number of extensions: 3097366
Number of successful extensions: 20513
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 164
Number of HSP's successfully gapped in prelim test: 706
Number of HSP's that attempted gapping in prelim test: 12746
Number of HSP's gapped (non-prelim): 4995
length of query: 1341
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1227
effective length of database: 13,930,794
effective search space: 17093084238
effective search space used: 17093084238
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.