Guide to the Human Genome
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Search of human proteins with 52694752

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|52694752 glycoprotein (transmembrane) nmb isoform a
precursor [Homo sapiens]
         (572 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|52694752 glycoprotein (transmembrane) nmb isoform a precursor...  1194   0.0  
gi|4505405 glycoprotein (transmembrane) nmb isoform b precursor ...  1161   0.0  
gi|5902084 silver homolog [Homo sapiens]                              166   4e-41
gi|197313781 transmembrane protein 130 isoform c [Homo sapiens]        46   8e-05
gi|197313779 transmembrane protein 130 isoform a [Homo sapiens]        46   8e-05
gi|23097274 transmembrane protein 130 isoform b [Homo sapiens]         46   8e-05
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    41   0.003
gi|156416026 zinc finger protein 219 [Homo sapiens]                    40   0.008
gi|156415998 zinc finger protein 219 [Homo sapiens]                    40   0.008
gi|156415996 zinc finger protein 219 [Homo sapiens]                    40   0.008
gi|40548415 dishevelled associated activator of morphogenesis 2 ...    39   0.010
gi|47132519 Ras association and pleckstrin homology domains 1 is...    38   0.022
gi|150170670 piccolo isoform 2 [Homo sapiens]                          38   0.022
gi|150378539 piccolo isoform 1 [Homo sapiens]                          38   0.022
gi|110556644 zinc finger protein, multitype 1 [Homo sapiens]           38   0.022
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap...    37   0.037
gi|52485606 formin-like 2 [Homo sapiens]                               37   0.037
gi|148886716 downstream of Stk11 [Homo sapiens]                        37   0.037
gi|21071058 SWI/SNF-related matrix-associated actin-dependent re...    37   0.064
gi|205360962 polycystin 1 isoform 2 precursor [Homo sapiens]           37   0.064
gi|205360954 polycystin 1 isoform 1 precursor [Homo sapiens]           37   0.064
gi|11034811 catenin (cadherin-associated protein), delta 2 (neur...    37   0.064
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo...    37   0.064
gi|39812378 RAN binding protein 9 [Homo sapiens]                       36   0.084
gi|239755323 PREDICTED: hypothetical protein XP_002344527 [Homo ...    36   0.084
gi|239749816 PREDICTED: hypothetical protein [Homo sapiens]            36   0.084
gi|239744106 PREDICTED: hypothetical protein XP_002343034 [Homo ...    36   0.084
gi|33946282 hypothetical protein LOC25962 isoform 1 [Homo sapiens]     36   0.084
gi|33946280 hypothetical protein LOC25962 isoform 2 [Homo sapiens]     36   0.084
gi|195972805 myocyte enhancer factor 2A isoform 4 [Homo sapiens]       36   0.11 

>gi|52694752 glycoprotein (transmembrane) nmb isoform a precursor
           [Homo sapiens]
          Length = 572

 Score = 1194 bits (3088), Expect = 0.0
 Identities = 572/572 (100%), Positives = 572/572 (100%)

Query: 1   MECLYYFLGFLLLAARLPLDAAKRFHDVLGNERPSAYMREHNQLNGWSSDENDWNEKLYP 60
           MECLYYFLGFLLLAARLPLDAAKRFHDVLGNERPSAYMREHNQLNGWSSDENDWNEKLYP
Sbjct: 1   MECLYYFLGFLLLAARLPLDAAKRFHDVLGNERPSAYMREHNQLNGWSSDENDWNEKLYP 60

Query: 61  VWKRGDMRWKNSWKGGRVQAVLTSDSPALVGSNITFAVNLIFPRCQKEDANGNIVYEKNC 120
           VWKRGDMRWKNSWKGGRVQAVLTSDSPALVGSNITFAVNLIFPRCQKEDANGNIVYEKNC
Sbjct: 61  VWKRGDMRWKNSWKGGRVQAVLTSDSPALVGSNITFAVNLIFPRCQKEDANGNIVYEKNC 120

Query: 121 RNEAGLSADPYVYNWTAWSEDSDGENGTGQSHHNVFPDGKPFPHHPGWRRWNFIYVFHTL 180
           RNEAGLSADPYVYNWTAWSEDSDGENGTGQSHHNVFPDGKPFPHHPGWRRWNFIYVFHTL
Sbjct: 121 RNEAGLSADPYVYNWTAWSEDSDGENGTGQSHHNVFPDGKPFPHHPGWRRWNFIYVFHTL 180

Query: 181 GQYFQKLGRCSVRVSVNTANVTLGPQLMEVTVYRRHGRAYVPIAQVKDVYVVTDQIPVFV 240
           GQYFQKLGRCSVRVSVNTANVTLGPQLMEVTVYRRHGRAYVPIAQVKDVYVVTDQIPVFV
Sbjct: 181 GQYFQKLGRCSVRVSVNTANVTLGPQLMEVTVYRRHGRAYVPIAQVKDVYVVTDQIPVFV 240

Query: 241 TMFQKNDRNSSDETFLKDLPIMFDVLIHDPSHFLNYSTINYKWSFGDNTGLFVSTNHTVN 300
           TMFQKNDRNSSDETFLKDLPIMFDVLIHDPSHFLNYSTINYKWSFGDNTGLFVSTNHTVN
Sbjct: 241 TMFQKNDRNSSDETFLKDLPIMFDVLIHDPSHFLNYSTINYKWSFGDNTGLFVSTNHTVN 300

Query: 301 HTYVLNGTFSLNLTVKAAAPGPCPPPPPPPRPSKPTPSLATTLKSYDSNTPGPAGDNPLE 360
           HTYVLNGTFSLNLTVKAAAPGPCPPPPPPPRPSKPTPSLATTLKSYDSNTPGPAGDNPLE
Sbjct: 301 HTYVLNGTFSLNLTVKAAAPGPCPPPPPPPRPSKPTPSLATTLKSYDSNTPGPAGDNPLE 360

Query: 361 LSRIPDENCQINRYGHFQATITIVEGILEVNIIQMTDVLMPVPWPESSLIDFVVTCQGSI 420
           LSRIPDENCQINRYGHFQATITIVEGILEVNIIQMTDVLMPVPWPESSLIDFVVTCQGSI
Sbjct: 361 LSRIPDENCQINRYGHFQATITIVEGILEVNIIQMTDVLMPVPWPESSLIDFVVTCQGSI 420

Query: 421 PTEVCTIISDPTCEITQNTVCSPVDVDEMCLLTVRRTFNGSGTYCVNLTLGDDTSLALTS 480
           PTEVCTIISDPTCEITQNTVCSPVDVDEMCLLTVRRTFNGSGTYCVNLTLGDDTSLALTS
Sbjct: 421 PTEVCTIISDPTCEITQNTVCSPVDVDEMCLLTVRRTFNGSGTYCVNLTLGDDTSLALTS 480

Query: 481 TLISVPDRDPASPLRMANSALISVGCLAIFVTVISLLVYKKHKEYNPIENSPGNVVRSKG 540
           TLISVPDRDPASPLRMANSALISVGCLAIFVTVISLLVYKKHKEYNPIENSPGNVVRSKG
Sbjct: 481 TLISVPDRDPASPLRMANSALISVGCLAIFVTVISLLVYKKHKEYNPIENSPGNVVRSKG 540

Query: 541 LSVFLNRAKAVFFPGNQEKDPLLKNQEFKGVS 572
           LSVFLNRAKAVFFPGNQEKDPLLKNQEFKGVS
Sbjct: 541 LSVFLNRAKAVFFPGNQEKDPLLKNQEFKGVS 572


>gi|4505405 glycoprotein (transmembrane) nmb isoform b precursor
           [Homo sapiens]
          Length = 560

 Score = 1161 bits (3003), Expect = 0.0
 Identities = 560/572 (97%), Positives = 560/572 (97%), Gaps = 12/572 (2%)

Query: 1   MECLYYFLGFLLLAARLPLDAAKRFHDVLGNERPSAYMREHNQLNGWSSDENDWNEKLYP 60
           MECLYYFLGFLLLAARLPLDAAKRFHDVLGNERPSAYMREHNQLNGWSSDENDWNEKLYP
Sbjct: 1   MECLYYFLGFLLLAARLPLDAAKRFHDVLGNERPSAYMREHNQLNGWSSDENDWNEKLYP 60

Query: 61  VWKRGDMRWKNSWKGGRVQAVLTSDSPALVGSNITFAVNLIFPRCQKEDANGNIVYEKNC 120
           VWKRGDMRWKNSWKGGRVQAVLTSDSPALVGSNITFAVNLIFPRCQKEDANGNIVYEKNC
Sbjct: 61  VWKRGDMRWKNSWKGGRVQAVLTSDSPALVGSNITFAVNLIFPRCQKEDANGNIVYEKNC 120

Query: 121 RNEAGLSADPYVYNWTAWSEDSDGENGTGQSHHNVFPDGKPFPHHPGWRRWNFIYVFHTL 180
           RNEAGLSADPYVYNWTAWSEDSDGENGTGQSHHNVFPDGKPFPHHPGWRRWNFIYVFHTL
Sbjct: 121 RNEAGLSADPYVYNWTAWSEDSDGENGTGQSHHNVFPDGKPFPHHPGWRRWNFIYVFHTL 180

Query: 181 GQYFQKLGRCSVRVSVNTANVTLGPQLMEVTVYRRHGRAYVPIAQVKDVYVVTDQIPVFV 240
           GQYFQKLGRCSVRVSVNTANVTLGPQLMEVTVYRRHGRAYVPIAQVKDVYVVTDQIPVFV
Sbjct: 181 GQYFQKLGRCSVRVSVNTANVTLGPQLMEVTVYRRHGRAYVPIAQVKDVYVVTDQIPVFV 240

Query: 241 TMFQKNDRNSSDETFLKDLPIMFDVLIHDPSHFLNYSTINYKWSFGDNTGLFVSTNHTVN 300
           TMFQKNDRNSSDETFLKDLPIMFDVLIHDPSHFLNYSTINYKWSFGDNTGLFVSTNHTVN
Sbjct: 241 TMFQKNDRNSSDETFLKDLPIMFDVLIHDPSHFLNYSTINYKWSFGDNTGLFVSTNHTVN 300

Query: 301 HTYVLNGTFSLNLTVKAAAPGPCPPPPPPPRPSKPTPSLATTLKSYDSNTPGPAGDNPLE 360
           HTYVLNGTFSLNLTVKAAAPGPCPPPPPPPRPSKPTPSL            GPAGDNPLE
Sbjct: 301 HTYVLNGTFSLNLTVKAAAPGPCPPPPPPPRPSKPTPSL------------GPAGDNPLE 348

Query: 361 LSRIPDENCQINRYGHFQATITIVEGILEVNIIQMTDVLMPVPWPESSLIDFVVTCQGSI 420
           LSRIPDENCQINRYGHFQATITIVEGILEVNIIQMTDVLMPVPWPESSLIDFVVTCQGSI
Sbjct: 349 LSRIPDENCQINRYGHFQATITIVEGILEVNIIQMTDVLMPVPWPESSLIDFVVTCQGSI 408

Query: 421 PTEVCTIISDPTCEITQNTVCSPVDVDEMCLLTVRRTFNGSGTYCVNLTLGDDTSLALTS 480
           PTEVCTIISDPTCEITQNTVCSPVDVDEMCLLTVRRTFNGSGTYCVNLTLGDDTSLALTS
Sbjct: 409 PTEVCTIISDPTCEITQNTVCSPVDVDEMCLLTVRRTFNGSGTYCVNLTLGDDTSLALTS 468

Query: 481 TLISVPDRDPASPLRMANSALISVGCLAIFVTVISLLVYKKHKEYNPIENSPGNVVRSKG 540
           TLISVPDRDPASPLRMANSALISVGCLAIFVTVISLLVYKKHKEYNPIENSPGNVVRSKG
Sbjct: 469 TLISVPDRDPASPLRMANSALISVGCLAIFVTVISLLVYKKHKEYNPIENSPGNVVRSKG 528

Query: 541 LSVFLNRAKAVFFPGNQEKDPLLKNQEFKGVS 572
           LSVFLNRAKAVFFPGNQEKDPLLKNQEFKGVS
Sbjct: 529 LSVFLNRAKAVFFPGNQEKDPLLKNQEFKGVS 560


>gi|5902084 silver homolog [Homo sapiens]
          Length = 661

 Score =  166 bits (421), Expect = 4e-41
 Identities = 93/292 (31%), Positives = 149/292 (51%), Gaps = 21/292 (7%)

Query: 54  WNEKLYPVWKRGDMRWKNSWKGGRVQAVLTSDSPALVGSNITFAVNLIFPRCQKEDANGN 113
           WN +LYP W        + W+GG+V   +++D P L+G+N +F++ L FP  QK   +G 
Sbjct: 44  WNRQLYPEWTEAQRL--DCWRGGQVSLKVSNDGPTLIGANASFSIALNFPGSQKVLPDGQ 101

Query: 114 IVYEKNCRNEAGLSADPYVYNWTAWSEDSDGENGTGQSHHNVFPDGKPFPHHPGWRRWNF 173
           +++  N            +     W         T  +   +FPDG P P     ++ +F
Sbjct: 102 VIWVNNT----------IINGSQVWGGQPVYPQETDDAC--IFPDGGPCPSGSWSQKRSF 149

Query: 174 IYVFHTLGQYFQKLGRCSVRVSVNTANVTLGPQLMEVTVYRRHG-RAYVPIAQVKDVYVV 232
           +YV+ T GQY+Q LG     +S+ T    LG   MEVTVY R G R+YVP+A     + +
Sbjct: 150 VYVWKTWGQYWQVLGGPVSGLSIGTGRAMLGTHTMEVTVYHRRGSRSYVPLAHSSSAFTI 209

Query: 233 TDQIPVFVTMFQKNDRNSSDETFLKDLPIMFDVLIHDPSHFLNYSTINYKWSFGDNTGLF 292
           TDQ+P  V++ Q    +  ++ FL++ P+ F + +HDPS +L  + ++Y W FGD++G  
Sbjct: 210 TDQVPFSVSVSQLRALDGGNKHFLRNQPLTFALQLHDPSGYLAEADLSYTWDFGDSSGTL 269

Query: 293 VSTNHTVNHTYVLNGTFSLNLTVKAAAP------GPCPPPPPPPRPSKPTPS 338
           +S    V HTY+  G  +  + ++AA P       P P      RP+   P+
Sbjct: 270 ISRALVVTHTYLEPGPVTAQVVLQAAIPLTSCGSSPVPGTTDGHRPTAEAPN 321



 Score = 97.8 bits (242), Expect = 2e-20
 Identities = 61/198 (30%), Positives = 95/198 (47%), Gaps = 15/198 (7%)

Query: 328 PPPRPSKPTPSLATTLKSYDSNTPGPAGDNPLELSRIPDE---NCQINRYGHFQATITIV 384
           P P P  P  S   + +S   +  GP  D    L  +  +   +C + RYG F  T+ IV
Sbjct: 432 PIPEPEGPDASSIMSTESITGSL-GPLLDGTATLRLVKRQVPLDCVLYRYGSFSVTLDIV 490

Query: 385 EGILEVNIIQMTDVLMPVPWPESSLIDFVVTCQGSIPTEVCTIISDPTCEITQNTVCSPV 444
           +GI      +  ++L  VP  E    +  V+CQG +P E C  IS P C+     +C PV
Sbjct: 491 QGI------ESAEILQAVPSGEGDAFELTVSCQGGLPKEACMEISSPGCQPPAQRLCQPV 544

Query: 445 DVDEMCLLTVRRTF-NGSGTYCVNLTLGDDTSLALTSTLISVPDRDPASPLRMANSALIS 503
                C L + +    GSGTYC+N++L D  SLA+ ST + +P ++      +    LI 
Sbjct: 545 LPSPACQLVLHQILKGGSGTYCLNVSLADTNSLAVVSTQLIMPGQEAG----LGQVPLIV 600

Query: 504 VGCLAIFVTVISLLVYKK 521
              L +   V++ L+Y++
Sbjct: 601 GILLVLMAVVLASLIYRR 618


>gi|197313781 transmembrane protein 130 isoform c [Homo sapiens]
          Length = 321

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 23/64 (35%), Positives = 36/64 (56%), Gaps = 1/64 (1%)

Query: 254 TFLKDLPIMFDVLIHDPSHFLNYSTINYKWSFGDNTGLFVSTNHTVNHTYVLNGTFSLNL 313
           ++L    +    L+HDPS+FL  +   Y W FGD T + V+ +  V + Y + GTF++ L
Sbjct: 48  SYLTKTVLKVSFLLHDPSNFLKTALFLYSWDFGDGTQM-VTEDSVVYYNYSIIGTFTVKL 106

Query: 314 TVKA 317
            V A
Sbjct: 107 KVVA 110


>gi|197313779 transmembrane protein 130 isoform a [Homo sapiens]
          Length = 435

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 23/64 (35%), Positives = 36/64 (56%), Gaps = 1/64 (1%)

Query: 254 TFLKDLPIMFDVLIHDPSHFLNYSTINYKWSFGDNTGLFVSTNHTVNHTYVLNGTFSLNL 313
           ++L    +    L+HDPS+FL  +   Y W FGD T + V+ +  V + Y + GTF++ L
Sbjct: 150 SYLTKTVLKVSFLLHDPSNFLKTALFLYSWDFGDGTQM-VTEDSVVYYNYSIIGTFTVKL 208

Query: 314 TVKA 317
            V A
Sbjct: 209 KVVA 212


>gi|23097274 transmembrane protein 130 isoform b [Homo sapiens]
          Length = 423

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 23/64 (35%), Positives = 36/64 (56%), Gaps = 1/64 (1%)

Query: 254 TFLKDLPIMFDVLIHDPSHFLNYSTINYKWSFGDNTGLFVSTNHTVNHTYVLNGTFSLNL 313
           ++L    +    L+HDPS+FL  +   Y W FGD T + V+ +  V + Y + GTF++ L
Sbjct: 150 SYLTKTVLKVSFLLHDPSNFLKTALFLYSWDFGDGTQM-VTEDSVVYYNYSIIGTFTVKL 208

Query: 314 TVKA 317
            V A
Sbjct: 209 KVVA 212


>gi|155030232 proline, glutamic acid and leucine rich protein 1
           [Homo sapiens]
          Length = 1130

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 21/43 (48%), Positives = 22/43 (51%), Gaps = 1/43 (2%)

Query: 318 AAPGPCPPPPPPPRPSKPTPSLATTLKSYDSNTPGPAGDNPLE 360
           AAPGP PPPPPPP P  P P      +     TPG  G   LE
Sbjct: 834 AAPGPLPPPPPPP-PPVPGPVTLPPPQLVPEGTPGGGGPPALE 875



 Score = 31.2 bits (69), Expect = 2.7
 Identities = 16/41 (39%), Positives = 19/41 (46%)

Query: 325 PPPPPPRPSKPTPSLATTLKSYDSNTPGPAGDNPLELSRIP 365
           PP PPP PS  TP          ++ P PA + P EL   P
Sbjct: 796 PPLPPPPPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAP 836


>gi|156416026 zinc finger protein 219 [Homo sapiens]
          Length = 722

 Score = 39.7 bits (91), Expect = 0.008
 Identities = 25/76 (32%), Positives = 35/76 (46%), Gaps = 5/76 (6%)

Query: 299 VNHTYVLNGTFSLNLTVKAAAPGPCPPPPPPPRP---SKPTPSLATTLKSYDSNTPGPAG 355
           ++H+   +G     L   +AAP P P P PPP+P   S P P      +   + TP PA 
Sbjct: 205 LHHSLTAHGAPERPLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEPEPEREATPTPAPAA 264

Query: 356 DNPLELSRIPDENCQI 371
             P E    P+  CQ+
Sbjct: 265 --PEEPPAPPEFRCQV 278



 Score = 34.3 bits (77), Expect = 0.32
 Identities = 18/48 (37%), Positives = 24/48 (50%), Gaps = 7/48 (14%)

Query: 318 AAPGPCPPPPPPPR-------PSKPTPSLATTLKSYDSNTPGPAGDNP 358
           A PGP P PPPP +        +KP+P  AT ++   S  P  +G  P
Sbjct: 556 AGPGPPPEPPPPSQRGSAPQSGAKPSPQPATWVEGASSPRPPSSGAGP 603


>gi|156415998 zinc finger protein 219 [Homo sapiens]
          Length = 722

 Score = 39.7 bits (91), Expect = 0.008
 Identities = 25/76 (32%), Positives = 35/76 (46%), Gaps = 5/76 (6%)

Query: 299 VNHTYVLNGTFSLNLTVKAAAPGPCPPPPPPPRP---SKPTPSLATTLKSYDSNTPGPAG 355
           ++H+   +G     L   +AAP P P P PPP+P   S P P      +   + TP PA 
Sbjct: 205 LHHSLTAHGAPERPLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEPEPEREATPTPAPAA 264

Query: 356 DNPLELSRIPDENCQI 371
             P E    P+  CQ+
Sbjct: 265 --PEEPPAPPEFRCQV 278



 Score = 34.3 bits (77), Expect = 0.32
 Identities = 18/48 (37%), Positives = 24/48 (50%), Gaps = 7/48 (14%)

Query: 318 AAPGPCPPPPPPPR-------PSKPTPSLATTLKSYDSNTPGPAGDNP 358
           A PGP P PPPP +        +KP+P  AT ++   S  P  +G  P
Sbjct: 556 AGPGPPPEPPPPSQRGSAPQSGAKPSPQPATWVEGASSPRPPSSGAGP 603


>gi|156415996 zinc finger protein 219 [Homo sapiens]
          Length = 722

 Score = 39.7 bits (91), Expect = 0.008
 Identities = 25/76 (32%), Positives = 35/76 (46%), Gaps = 5/76 (6%)

Query: 299 VNHTYVLNGTFSLNLTVKAAAPGPCPPPPPPPRP---SKPTPSLATTLKSYDSNTPGPAG 355
           ++H+   +G     L   +AAP P P P PPP+P   S P P      +   + TP PA 
Sbjct: 205 LHHSLTAHGAPERPLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEPEPEREATPTPAPAA 264

Query: 356 DNPLELSRIPDENCQI 371
             P E    P+  CQ+
Sbjct: 265 --PEEPPAPPEFRCQV 278



 Score = 34.3 bits (77), Expect = 0.32
 Identities = 18/48 (37%), Positives = 24/48 (50%), Gaps = 7/48 (14%)

Query: 318 AAPGPCPPPPPPPR-------PSKPTPSLATTLKSYDSNTPGPAGDNP 358
           A PGP P PPPP +        +KP+P  AT ++   S  P  +G  P
Sbjct: 556 AGPGPPPEPPPPSQRGSAPQSGAKPSPQPATWVEGASSPRPPSSGAGP 603


>gi|40548415 dishevelled associated activator of morphogenesis 2
           [Homo sapiens]
          Length = 1067

 Score = 39.3 bits (90), Expect = 0.010
 Identities = 30/106 (28%), Positives = 44/106 (41%), Gaps = 14/106 (13%)

Query: 308 TFSLNLTVKAAAPGP-------CPPPPPPPRP--SKPTPSLATTLKSYD---SNTPGPAG 355
           T S ++T     P P       CPPPPPPP P    PTP  A             P P+ 
Sbjct: 530 TLSSSMTTNDLPPPPPPLPFACCPPPPPPPLPPGGPPTPPGAPPCLGMGLPLPQDPYPSS 589

Query: 356 DNPLELSRIPDENCQINRYGHFQATITIVEGIL--EVNIIQMTDVL 399
           D PL   R+P  +  +  +   +     V G +  E++ +Q+  +L
Sbjct: 590 DVPLRKKRVPQPSHPLKSFNWVKLNEERVPGTVWNEIDDMQVFRIL 635


>gi|47132519 Ras association and pleckstrin homology domains 1
           isoform 1 [Homo sapiens]
          Length = 1250

 Score = 38.1 bits (87), Expect = 0.022
 Identities = 18/40 (45%), Positives = 21/40 (52%), Gaps = 1/40 (2%)

Query: 319 APGPCPPPPPPPRPSKPTPSLATTLKSYDSNTPGPAGDNP 358
           +P P PPPPPPP  S PTP  + +     S T  P G  P
Sbjct: 933 SPVPAPPPPPPPTAS-PTPDKSGSPGKKTSKTSSPGGKKP 971



 Score = 34.7 bits (78), Expect = 0.24
 Identities = 15/32 (46%), Positives = 17/32 (53%)

Query: 320 PGPCPPPPPPPRPSKPTPSLATTLKSYDSNTP 351
           P P PPPPPPP P  P P  + +  S  S  P
Sbjct: 631 PPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAP 662



 Score = 34.3 bits (77), Expect = 0.32
 Identities = 13/20 (65%), Positives = 13/20 (65%)

Query: 320 PGPCPPPPPPPRPSKPTPSL 339
           P P PPPPPPP P  P P L
Sbjct: 630 PPPPPPPPPPPPPPPPPPPL 649



 Score = 33.9 bits (76), Expect = 0.41
 Identities = 18/51 (35%), Positives = 23/51 (45%)

Query: 314 TVKAAAPGPCPPPPPPPRPSKPTPSLATTLKSYDSNTPGPAGDNPLELSRI 364
           T    +P   PPPPPPP P  P P     L S  + + G A    ++ S I
Sbjct: 620 TASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTI 670



 Score = 30.8 bits (68), Expect = 3.5
 Identities = 21/69 (30%), Positives = 30/69 (43%), Gaps = 7/69 (10%)

Query: 273 FLNYSTINYKWSFGDNTG-LFVSTNHTVNHTYVLNGTFSLNLTVKAAAPGPCPPPPPPPR 331
           F+ YSTI    +   ++G LF      V  +       S+   +     G  PPPPPPP 
Sbjct: 664 FVKYSTITRLQNASQHSGALFKPPTPPVMQSQ------SVKPQILVPPNGVVPPPPPPPP 717

Query: 332 PSKPTPSLA 340
           P  P  ++A
Sbjct: 718 PPTPGSAMA 726


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 38.1 bits (87), Expect = 0.022
 Identities = 15/30 (50%), Positives = 19/30 (63%)

Query: 310  SLNLTVKAAAPGPCPPPPPPPRPSKPTPSL 339
            SL+++ +   P P PPPPPPP P  P P L
Sbjct: 2398 SLDISAQPPPPPPPPPPPPPPPPPPPPPPL 2427



 Score = 37.4 bits (85), Expect = 0.037
 Identities = 15/28 (53%), Positives = 17/28 (60%)

Query: 310  SLNLTVKAAAPGPCPPPPPPPRPSKPTP 337
            S +L + A  P P PPPPPPP P  P P
Sbjct: 2396 SSSLDISAQPPPPPPPPPPPPPPPPPPP 2423



 Score = 33.1 bits (74), Expect = 0.71
 Identities = 12/18 (66%), Positives = 12/18 (66%)

Query: 320  PGPCPPPPPPPRPSKPTP 337
            P P PPPPPPP P  P P
Sbjct: 2411 PPPPPPPPPPPPPPPPLP 2428



 Score = 33.1 bits (74), Expect = 0.71
 Identities = 12/19 (63%), Positives = 13/19 (68%)

Query: 320  PGPCPPPPPPPRPSKPTPS 338
            P P PPPPPPP P  P P+
Sbjct: 2413 PPPPPPPPPPPPPPLPPPT 2431



 Score = 32.7 bits (73), Expect = 0.92
 Identities = 17/48 (35%), Positives = 20/48 (41%), Gaps = 9/48 (18%)

Query: 320 PGPCPPPPPPPRPSKPTPSLATTLKSYDS---------NTPGPAGDNP 358
           PGP  PPP  P P+KP P    + K               PGPA  +P
Sbjct: 474 PGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSP 521



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 13/29 (44%), Positives = 17/29 (58%)

Query: 309  FSLNLTVKAAAPGPCPPPPPPPRPSKPTP 337
            F  + ++  +A  P PPPPPPP P  P P
Sbjct: 2393 FFRSSSLDISAQPPPPPPPPPPPPPPPPP 2421



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 13/24 (54%), Positives = 14/24 (58%)

Query: 320  PGPCPPPPPPPRPSKPTPSLATTL 343
            P P PPPPPPP P  P  S   T+
Sbjct: 2414 PPPPPPPPPPPPPLPPPTSPKPTI 2437


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 38.1 bits (87), Expect = 0.022
 Identities = 15/30 (50%), Positives = 19/30 (63%)

Query: 310  SLNLTVKAAAPGPCPPPPPPPRPSKPTPSL 339
            SL+++ +   P P PPPPPPP P  P P L
Sbjct: 2398 SLDISAQPPPPPPPPPPPPPPPPPPPPPPL 2427



 Score = 37.4 bits (85), Expect = 0.037
 Identities = 15/28 (53%), Positives = 17/28 (60%)

Query: 310  SLNLTVKAAAPGPCPPPPPPPRPSKPTP 337
            S +L + A  P P PPPPPPP P  P P
Sbjct: 2396 SSSLDISAQPPPPPPPPPPPPPPPPPPP 2423



 Score = 33.1 bits (74), Expect = 0.71
 Identities = 12/18 (66%), Positives = 12/18 (66%)

Query: 320  PGPCPPPPPPPRPSKPTP 337
            P P PPPPPPP P  P P
Sbjct: 2411 PPPPPPPPPPPPPPPPLP 2428



 Score = 33.1 bits (74), Expect = 0.71
 Identities = 12/19 (63%), Positives = 13/19 (68%)

Query: 320  PGPCPPPPPPPRPSKPTPS 338
            P P PPPPPPP P  P P+
Sbjct: 2413 PPPPPPPPPPPPPPLPPPT 2431



 Score = 32.7 bits (73), Expect = 0.92
 Identities = 17/48 (35%), Positives = 20/48 (41%), Gaps = 9/48 (18%)

Query: 320 PGPCPPPPPPPRPSKPTPSLATTLKSYDS---------NTPGPAGDNP 358
           PGP  PPP  P P+KP P    + K               PGPA  +P
Sbjct: 474 PGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSP 521



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 13/29 (44%), Positives = 17/29 (58%)

Query: 309  FSLNLTVKAAAPGPCPPPPPPPRPSKPTP 337
            F  + ++  +A  P PPPPPPP P  P P
Sbjct: 2393 FFRSSSLDISAQPPPPPPPPPPPPPPPPP 2421



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 13/24 (54%), Positives = 14/24 (58%)

Query: 320  PGPCPPPPPPPRPSKPTPSLATTL 343
            P P PPPPPPP P  P  S   T+
Sbjct: 2414 PPPPPPPPPPPPPLPPPTSPKPTI 2437


>gi|110556644 zinc finger protein, multitype 1 [Homo sapiens]
          Length = 1006

 Score = 38.1 bits (87), Expect = 0.022
 Identities = 19/47 (40%), Positives = 25/47 (53%), Gaps = 5/47 (10%)

Query: 324 PPPPPP---PRPSKPTPSLATTLKS--YDSNTPGPAGDNPLELSRIP 365
           PPPPPP   P P  P P   +        + +PGPA D P++LS+ P
Sbjct: 755 PPPPPPGHAPAPESPRPGSGSGSGPGLAPARSPGPAADGPIDLSKKP 801


>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
           sapiens]
          Length = 505

 Score = 37.4 bits (85), Expect = 0.037
 Identities = 29/107 (27%), Positives = 43/107 (40%), Gaps = 13/107 (12%)

Query: 313 LTVKAAAPGPCPPPPPPPRPSKPTPSLATTLKSYDSNTPGPAGDNP---------LELSR 363
           L V   AP P PPPPPPP P  P P L +     D   P  AG+            +L +
Sbjct: 366 LGVGPVAPPPPPPPPPPPGP-PPPPGLPS---DGDHQVPTTAGNKAALLDQIREGAQLKK 421

Query: 364 IPDENCQINRYGHFQATITIVEGILEVNIIQMTDVLMPVPWPESSLI 410
           +   +  ++  G       I +GI   ++    +   P P P S ++
Sbjct: 422 VEQNSRPVSCSGRDALLDQIRQGIQLKSVADGQESTPPTPAPTSGIV 468



 Score = 31.2 bits (69), Expect = 2.7
 Identities = 12/19 (63%), Positives = 12/19 (63%)

Query: 319 APGPCPPPPPPPRPSKPTP 337
           AP   PPPPPP RPS   P
Sbjct: 317 APTAAPPPPPPSRPSVAVP 335


>gi|52485606 formin-like 2 [Homo sapiens]
          Length = 1092

 Score = 37.4 bits (85), Expect = 0.037
 Identities = 16/28 (57%), Positives = 19/28 (67%)

Query: 310 SLNLTVKAAAPGPCPPPPPPPRPSKPTP 337
           S+  T+ AA+ GP PPPPPP  PS  TP
Sbjct: 513 SVGPTMGAASSGPLPPPPPPLPPSSDTP 540



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 17/37 (45%), Positives = 18/37 (48%), Gaps = 11/37 (29%)

Query: 320 PGPCPPPPPPPRPSKPTPSLATTLKSYDSNTPGPAGD 356
           P P PPPPPPP P  P P L           PGPA +
Sbjct: 555 PPPPPPPPPPPPPPPPPPPL-----------PGPAAE 580



 Score = 33.9 bits (76), Expect = 0.41
 Identities = 13/22 (59%), Positives = 14/22 (63%)

Query: 320 PGPCPPPPPPPRPSKPTPSLAT 341
           P P PPPPPPP P  P P+  T
Sbjct: 560 PPPPPPPPPPPPPPLPGPAAET 581



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 19/51 (37%), Positives = 22/51 (43%), Gaps = 9/51 (17%)

Query: 304 VLNGTFSLNLTVKAAAPGPCPPPPPPPRP---------SKPTPSLATTLKS 345
           V NG  +  +      P P PPPPPPP P         + P P LA  L S
Sbjct: 543 VQNGPVTPPMPPPPPPPPPPPPPPPPPPPPPLPGPAAETVPAPPLAPPLPS 593


>gi|148886716 downstream of Stk11 [Homo sapiens]
          Length = 447

 Score = 37.4 bits (85), Expect = 0.037
 Identities = 17/47 (36%), Positives = 22/47 (46%)

Query: 309 FSLNLTVKAAAPGPCPPPPPPPRPSKPTPSLATTLKSYDSNTPGPAG 355
           FS++   +    GPCPP PPP RP + +P    T     S    P G
Sbjct: 381 FSVDGGARGGPVGPCPPSPPPRRPRERSPGPVDTRSPASSGKAPPRG 427


>gi|21071058 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a5 [Homo sapiens]
          Length = 1052

 Score = 36.6 bits (83), Expect = 0.064
 Identities = 19/39 (48%), Positives = 23/39 (58%), Gaps = 1/39 (2%)

Query: 317 AAAPGPCPPPPPPPRPSKPTPSLATTLKSYDSNTPGPAG 355
           ++A  P PPPPP   PSKP  S+A+   S  SN  GP G
Sbjct: 2   SSAAEPPPPPPPESAPSKPAASIASG-GSNSSNKGGPEG 39


>gi|205360962 polycystin 1 isoform 2 precursor [Homo sapiens]
          Length = 4302

 Score = 36.6 bits (83), Expect = 0.064
 Identities = 24/91 (26%), Positives = 36/91 (39%), Gaps = 6/91 (6%)

Query: 232  VTDQIPVFVTMFQKNDR-NSSDETFLKDLPIMFDVLIHDPSHFLNYSTINYKWSFGDNTG 290
            +T Q+PV V     +     SD   +   P+ F      P    +   + Y W FGD + 
Sbjct: 1114 LTQQVPVSVRASLPSVAVGVSDGVLVAGRPVTFY-----PHPLPSPGGVLYTWDFGDGSP 1168

Query: 291  LFVSTNHTVNHTYVLNGTFSLNLTVKAAAPG 321
            +   +    NHTY   GT+ + L V     G
Sbjct: 1169 VLTQSQPAANHTYASRGTYHVRLEVNNTVSG 1199



 Score = 29.6 bits (65), Expect = 7.8
 Identities = 16/50 (32%), Positives = 27/50 (54%), Gaps = 7/50 (14%)

Query: 269  DPSHFLNYSTINYKWSFGD-NTGLFVSTNHTVNHTYVLNGTFSLNLTVKA 317
            +P+H+L      + W+FGD ++   V    TV H +  +GTF L L + +
Sbjct: 1320 NPAHYL------FDWTFGDGSSNTTVRGCPTVTHNFTRSGTFPLALVLSS 1363


>gi|205360954 polycystin 1 isoform 1 precursor [Homo sapiens]
          Length = 4303

 Score = 36.6 bits (83), Expect = 0.064
 Identities = 24/91 (26%), Positives = 36/91 (39%), Gaps = 6/91 (6%)

Query: 232  VTDQIPVFVTMFQKNDR-NSSDETFLKDLPIMFDVLIHDPSHFLNYSTINYKWSFGDNTG 290
            +T Q+PV V     +     SD   +   P+ F      P    +   + Y W FGD + 
Sbjct: 1114 LTQQVPVSVRASLPSVAVGVSDGVLVAGRPVTFY-----PHPLPSPGGVLYTWDFGDGSP 1168

Query: 291  LFVSTNHTVNHTYVLNGTFSLNLTVKAAAPG 321
            +   +    NHTY   GT+ + L V     G
Sbjct: 1169 VLTQSQPAANHTYASRGTYHVRLEVNNTVSG 1199



 Score = 29.6 bits (65), Expect = 7.8
 Identities = 16/50 (32%), Positives = 27/50 (54%), Gaps = 7/50 (14%)

Query: 269  DPSHFLNYSTINYKWSFGD-NTGLFVSTNHTVNHTYVLNGTFSLNLTVKA 317
            +P+H+L      + W+FGD ++   V    TV H +  +GTF L L + +
Sbjct: 1320 NPAHYL------FDWTFGDGSSNTTVRGCPTVTHNFTRSGTFPLALVLSS 1363


>gi|11034811 catenin (cadherin-associated protein), delta 2 (neural
           plakophilin-related arm-repeat protein) [Homo sapiens]
          Length = 1225

 Score = 36.6 bits (83), Expect = 0.064
 Identities = 25/69 (36%), Positives = 29/69 (42%), Gaps = 17/69 (24%)

Query: 308 TFSLNLTVKA---AAPGPCPPPPPPPR-------------PSKPTPSLATTLKSYDSNTP 351
           +FS   T +A   A P P PPPPPPPR             P  P  + A  L    S  P
Sbjct: 201 SFSQGTTSRAGHLAGPEPAPPPPPPPREPFAPSLGSAFHLPDAPPAAAAAALYYSSSTLP 260

Query: 352 G-PAGDNPL 359
             P G +PL
Sbjct: 261 APPRGGSPL 269


>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
           sapiens]
          Length = 483

 Score = 36.6 bits (83), Expect = 0.064
 Identities = 25/55 (45%), Positives = 28/55 (50%), Gaps = 5/55 (9%)

Query: 312 NLTVKAAAPGPC-PPPPPPPRPSKPTPSLATTLKSYDSNTPGPAGDNPLELSRIP 365
           NL V  A P PC PPPPPPP P  P P    ++ S  +  P  A   PL L  IP
Sbjct: 211 NLPV-VAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLA---PLHLPPIP 261



 Score = 35.0 bits (79), Expect = 0.19
 Identities = 21/62 (33%), Positives = 25/62 (40%), Gaps = 1/62 (1%)

Query: 305 LNGTFSLNLTVKAAAPGPCPPPPPPPRPSKPTPSLATTLKSYDS-NTPGPAGDNPLELSR 363
           L  T   +   + A P P  P PPPP P  P P L   L S     TP  +   PL    
Sbjct: 152 LGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGN 211

Query: 364 IP 365
           +P
Sbjct: 212 LP 213



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 11/16 (68%), Positives = 11/16 (68%)

Query: 322 PCPPPPPPPRPSKPTP 337
           P PPPPPPP P  P P
Sbjct: 2   PVPPPPPPPLPPPPPP 17


>gi|39812378 RAN binding protein 9 [Homo sapiens]
          Length = 729

 Score = 36.2 bits (82), Expect = 0.084
 Identities = 18/42 (42%), Positives = 20/42 (47%)

Query: 317 AAAPGPCPPPPPPPRPSKPTPSLATTLKSYDSNTPGPAGDNP 358
           A A  P PPPPPPP  S   P+         +  PGPAG  P
Sbjct: 78  ATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAGPGPAGGAP 119


>gi|239755323 PREDICTED: hypothetical protein XP_002344527 [Homo
           sapiens]
          Length = 152

 Score = 36.2 bits (82), Expect = 0.084
 Identities = 18/40 (45%), Positives = 25/40 (62%), Gaps = 5/40 (12%)

Query: 320 PGPCPPPP--PPPRPSKPTPSLATTLKSYDSNTPGPAGDN 357
           P P PPPP  PPP P    P+ A++L+   SN+ G +GD+
Sbjct: 69  PAPLPPPPSQPPPPPPLDPPASASSLR---SNSSGSSGDD 105


>gi|239749816 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 152

 Score = 36.2 bits (82), Expect = 0.084
 Identities = 18/40 (45%), Positives = 25/40 (62%), Gaps = 5/40 (12%)

Query: 320 PGPCPPPP--PPPRPSKPTPSLATTLKSYDSNTPGPAGDN 357
           P P PPPP  PPP P    P+ A++L+   SN+ G +GD+
Sbjct: 69  PAPLPPPPSQPPPPPPLDPPASASSLR---SNSSGSSGDD 105


>gi|239744106 PREDICTED: hypothetical protein XP_002343034 [Homo
           sapiens]
          Length = 152

 Score = 36.2 bits (82), Expect = 0.084
 Identities = 18/40 (45%), Positives = 25/40 (62%), Gaps = 5/40 (12%)

Query: 320 PGPCPPPP--PPPRPSKPTPSLATTLKSYDSNTPGPAGDN 357
           P P PPPP  PPP P    P+ A++L+   SN+ G +GD+
Sbjct: 69  PAPLPPPPSQPPPPPPLDPPASASSLR---SNSSGSSGDD 105


>gi|33946282 hypothetical protein LOC25962 isoform 1 [Homo sapiens]
          Length = 1812

 Score = 36.2 bits (82), Expect = 0.084
 Identities = 25/84 (29%), Positives = 34/84 (40%), Gaps = 11/84 (13%)

Query: 285 FGDNTGLFVSTNHTVNHT-YVLNGTF---------SLNLTVKAAAPGPCPPPPPPPRPSK 334
           + +NT +    N  VN    VL G +         S++  +      P PPPPPPP P +
Sbjct: 92  YDENTSIIFRPNSKVNTDGLVLRGWYNCLTLAIYGSVDRVISHDRDSP-PPPPPPPPPPQ 150

Query: 335 PTPSLATTLKSYDSNTPGPAGDNP 358
           P PSL    K  D         +P
Sbjct: 151 PQPSLKRNPKHADGEKEDQFNGSP 174


>gi|33946280 hypothetical protein LOC25962 isoform 2 [Homo sapiens]
          Length = 1147

 Score = 36.2 bits (82), Expect = 0.084
 Identities = 25/84 (29%), Positives = 34/84 (40%), Gaps = 11/84 (13%)

Query: 285 FGDNTGLFVSTNHTVNHT-YVLNGTF---------SLNLTVKAAAPGPCPPPPPPPRPSK 334
           + +NT +    N  VN    VL G +         S++  +      P PPPPPPP P +
Sbjct: 92  YDENTSIIFRPNSKVNTDGLVLRGWYNCLTLAIYGSVDRVISHDRDSP-PPPPPPPPPPQ 150

Query: 335 PTPSLATTLKSYDSNTPGPAGDNP 358
           P PSL    K  D         +P
Sbjct: 151 PQPSLKRNPKHADGEKEDQFNGSP 174


>gi|195972805 myocyte enhancer factor 2A isoform 4 [Homo sapiens]
          Length = 429

 Score = 35.8 bits (81), Expect = 0.11
 Identities = 22/58 (37%), Positives = 30/58 (51%), Gaps = 15/58 (25%)

Query: 324 PPPPPPPRPSKPTP------------SLATTLKSYD-SNTPGPAGD--NPLELSRIPD 366
           PPPPP P+P  P P            SL+++  SYD S+   P GD  +P+ L R P+
Sbjct: 353 PPPPPQPQPQPPQPQPRQEMGRSPVDSLSSSSSSYDGSDREDPRGDFHSPIVLGRPPN 410


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.428 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,029,285
Number of Sequences: 37866
Number of extensions: 1434269
Number of successful extensions: 21152
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 292
Number of HSP's successfully gapped in prelim test: 172
Number of HSP's that attempted gapping in prelim test: 14558
Number of HSP's gapped (non-prelim): 4329
length of query: 572
length of database: 18,247,518
effective HSP length: 108
effective length of query: 464
effective length of database: 14,157,990
effective search space: 6569307360
effective search space used: 6569307360
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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