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Search of human proteins with 5174751
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5174751 Yes-associated protein 1, 65kDa isoform 2 [Homo
sapiens]
(454 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5174751 Yes-associated protein 1, 65kDa isoform 2 [Homo sapiens] 915 0.0
gi|194306653 Yes-associated protein 1, 65kDa isoform 1 [Homo sap... 881 0.0
gi|13346498 WW domain containing transcription regulator 1 [Homo... 343 1e-94
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 60 3e-09
gi|56549696 E1A binding protein p400 [Homo sapiens] 57 3e-08
gi|40806207 WW domain containing E3 ubiquitin protein ligase 2 i... 55 2e-07
gi|156071470 hyperpolarization activated cyclic nucleotide-gated... 52 1e-06
gi|110431370 espin [Homo sapiens] 52 1e-06
gi|66346708 membrane associated guanylate kinase, WW and PDZ dom... 52 1e-06
gi|74272284 membrane associated guanylate kinase, WW and PDZ dom... 52 1e-06
gi|74272282 membrane associated guanylate kinase, WW and PDZ dom... 52 1e-06
gi|31317292 Smad ubiquitination regulatory factor 1 isoform 1 [H... 51 2e-06
gi|150170670 piccolo isoform 2 [Homo sapiens] 50 4e-06
gi|150378539 piccolo isoform 1 [Homo sapiens] 50 4e-06
gi|110347429 mediator complex subunit 12 [Homo sapiens] 50 6e-06
gi|238859557 regulatory factor X1 [Homo sapiens] 49 7e-06
gi|27436957 membrane associated guanylate kinase, WW and PDZ dom... 49 7e-06
gi|94536811 NEDD4-like ubiquitin-protein ligase 1 [Homo sapiens] 49 9e-06
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 49 1e-05
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 49 1e-05
gi|19924099 synapsin I isoform Ia [Homo sapiens] 49 1e-05
gi|19924097 synapsin I isoform Ib [Homo sapiens] 49 1e-05
gi|210032509 hypothetical protein LOC100130302 [Homo sapiens] 49 1e-05
gi|148277037 AP2 associated kinase 1 [Homo sapiens] 49 1e-05
gi|222352183 neural precursor cell expressed, developmentally do... 48 2e-05
gi|222352088 neural precursor cell expressed, developmentally do... 48 2e-05
gi|222352086 neural precursor cell expressed, developmentally do... 48 2e-05
gi|222352084 neural precursor cell expressed, developmentally do... 48 2e-05
gi|222352082 neural precursor cell expressed, developmentally do... 48 2e-05
gi|168229174 RNA binding motif protein 27 [Homo sapiens] 48 2e-05
>gi|5174751 Yes-associated protein 1, 65kDa isoform 2 [Homo sapiens]
Length = 454
Score = 915 bits (2366), Expect = 0.0
Identities = 454/454 (100%), Positives = 454/454 (100%)
Query: 1 MDPGQQPPPQPAPQGQGQPPSQPPQGQGPPSGPGQPAPAATQAAPQAPPAGHQIVHVRGD 60
MDPGQQPPPQPAPQGQGQPPSQPPQGQGPPSGPGQPAPAATQAAPQAPPAGHQIVHVRGD
Sbjct: 1 MDPGQQPPPQPAPQGQGQPPSQPPQGQGPPSGPGQPAPAATQAAPQAPPAGHQIVHVRGD 60
Query: 61 SETDLEALFNAVMNPKTANVPQTVPMRLRKLPDSFFKPPEPKSHSRQASTDAGTAGALTP 120
SETDLEALFNAVMNPKTANVPQTVPMRLRKLPDSFFKPPEPKSHSRQASTDAGTAGALTP
Sbjct: 61 SETDLEALFNAVMNPKTANVPQTVPMRLRKLPDSFFKPPEPKSHSRQASTDAGTAGALTP 120
Query: 121 QHVRAHSSPASLQLGAVSPGTLTPTGVVSGPAATPTAQHLRQSSFEIPDDVPLPAGWEMA 180
QHVRAHSSPASLQLGAVSPGTLTPTGVVSGPAATPTAQHLRQSSFEIPDDVPLPAGWEMA
Sbjct: 121 QHVRAHSSPASLQLGAVSPGTLTPTGVVSGPAATPTAQHLRQSSFEIPDDVPLPAGWEMA 180
Query: 181 KTSSGQRYFLNHIDQTTTWQDPRKAMLSQMNVTAPTSPPVQQNMMNSASAMNQRISQSAP 240
KTSSGQRYFLNHIDQTTTWQDPRKAMLSQMNVTAPTSPPVQQNMMNSASAMNQRISQSAP
Sbjct: 181 KTSSGQRYFLNHIDQTTTWQDPRKAMLSQMNVTAPTSPPVQQNMMNSASAMNQRISQSAP 240
Query: 241 VKQPPPLAPQSPQGGVMGGSNSNQQQQMRLQQLQMEKERLRLKQQELLRQVRPQELALRS 300
VKQPPPLAPQSPQGGVMGGSNSNQQQQMRLQQLQMEKERLRLKQQELLRQVRPQELALRS
Sbjct: 241 VKQPPPLAPQSPQGGVMGGSNSNQQQQMRLQQLQMEKERLRLKQQELLRQVRPQELALRS 300
Query: 301 QLPTLEQDGGTQNPVSSPGMSQELRTMTTNSSDPFLNSGTYHSRDESTDSGLSMSSYSVP 360
QLPTLEQDGGTQNPVSSPGMSQELRTMTTNSSDPFLNSGTYHSRDESTDSGLSMSSYSVP
Sbjct: 301 QLPTLEQDGGTQNPVSSPGMSQELRTMTTNSSDPFLNSGTYHSRDESTDSGLSMSSYSVP 360
Query: 361 RTPDDFLNSVDEMDTGDTINQSTLPSQQNRFPDYLEAIPGTNVDLGTLEGDGMNIEGEEL 420
RTPDDFLNSVDEMDTGDTINQSTLPSQQNRFPDYLEAIPGTNVDLGTLEGDGMNIEGEEL
Sbjct: 361 RTPDDFLNSVDEMDTGDTINQSTLPSQQNRFPDYLEAIPGTNVDLGTLEGDGMNIEGEEL 420
Query: 421 MPSLQEALSSDILNDMESVLAATKLDKESFLTWL 454
MPSLQEALSSDILNDMESVLAATKLDKESFLTWL
Sbjct: 421 MPSLQEALSSDILNDMESVLAATKLDKESFLTWL 454
>gi|194306653 Yes-associated protein 1, 65kDa isoform 1 [Homo
sapiens]
Length = 504
Score = 881 bits (2277), Expect = 0.0
Identities = 451/504 (89%), Positives = 452/504 (89%), Gaps = 50/504 (9%)
Query: 1 MDPGQQPPPQPAPQGQGQPPSQPPQGQGPPSGPGQPAPAATQAAPQAPPAGHQIVHVRGD 60
MDPGQQPPPQPAPQGQGQPPSQPPQGQGPPSGPGQPAPAATQAAPQAPPAGHQIVHVRGD
Sbjct: 1 MDPGQQPPPQPAPQGQGQPPSQPPQGQGPPSGPGQPAPAATQAAPQAPPAGHQIVHVRGD 60
Query: 61 SETDLEALFNAVMNPKTANVPQTVPMRLRKLPDSFFKPPEPKSHSRQASTDAGTAGALTP 120
SETDLEALFNAVMNPKTANVPQTVPMRLRKLPDSFFKPPEPKSHSRQASTDAGTAGALTP
Sbjct: 61 SETDLEALFNAVMNPKTANVPQTVPMRLRKLPDSFFKPPEPKSHSRQASTDAGTAGALTP 120
Query: 121 QHVRAHSSPASLQLGAVSPGTLTPTGVVSGPAATPTAQHLRQSSFEIPDDVPLPAGWEMA 180
QHVRAHSSPASLQLGAVSPGTLTPTGVVSGPAATPTAQHLRQSSFEIPDDVPLPAGWEMA
Sbjct: 121 QHVRAHSSPASLQLGAVSPGTLTPTGVVSGPAATPTAQHLRQSSFEIPDDVPLPAGWEMA 180
Query: 181 KTSSGQRYFLNHIDQTTTWQDPRKAMLSQMNVTAPTSPPVQQNMMNSAS----------- 229
KTSSGQRYFLNHIDQTTTWQDPRKAMLSQMNVTAPTSPPVQQNMMNSAS
Sbjct: 181 KTSSGQRYFLNHIDQTTTWQDPRKAMLSQMNVTAPTSPPVQQNMMNSASGPLPDGWEQAM 240
Query: 230 ---------------------------AMNQRISQSAPVKQPPPLAPQSPQGGVMGGSNS 262
AMNQRISQSAPVKQPPPLAPQSPQGGVMGGSNS
Sbjct: 241 TQDGEIYYINHKNKTTSWLDPRLDPRFAMNQRISQSAPVKQPPPLAPQSPQGGVMGGSNS 300
Query: 263 NQQQQMRLQQLQMEKERLRLKQQELLRQV------------RPQELALRSQLPTLEQDGG 310
NQQQQMRLQQLQMEKERLRLKQQELLRQ + QELALRSQLPTLEQDGG
Sbjct: 301 NQQQQMRLQQLQMEKERLRLKQQELLRQAMRNINPSTANSPKCQELALRSQLPTLEQDGG 360
Query: 311 TQNPVSSPGMSQELRTMTTNSSDPFLNSGTYHSRDESTDSGLSMSSYSVPRTPDDFLNSV 370
TQNPVSSPGMSQELRTMTTNSSDPFLNSGTYHSRDESTDSGLSMSSYSVPRTPDDFLNSV
Sbjct: 361 TQNPVSSPGMSQELRTMTTNSSDPFLNSGTYHSRDESTDSGLSMSSYSVPRTPDDFLNSV 420
Query: 371 DEMDTGDTINQSTLPSQQNRFPDYLEAIPGTNVDLGTLEGDGMNIEGEELMPSLQEALSS 430
DEMDTGDTINQSTLPSQQNRFPDYLEAIPGTNVDLGTLEGDGMNIEGEELMPSLQEALSS
Sbjct: 421 DEMDTGDTINQSTLPSQQNRFPDYLEAIPGTNVDLGTLEGDGMNIEGEELMPSLQEALSS 480
Query: 431 DILNDMESVLAATKLDKESFLTWL 454
DILNDMESVLAATKLDKESFLTWL
Sbjct: 481 DILNDMESVLAATKLDKESFLTWL 504
>gi|13346498 WW domain containing transcription regulator 1 [Homo
sapiens]
Length = 400
Score = 343 bits (881), Expect = 1e-94
Identities = 212/436 (48%), Positives = 275/436 (63%), Gaps = 65/436 (14%)
Query: 43 AAPQAPPAGHQIVHVRGDSETDLEALFNAVMNPKTANVPQTVPMRLRKLPDSFFKPPEPK 102
A P PP G Q++HV D +TDLEALFN+VMNPK ++ R + LP+SFFK P+
Sbjct: 6 APPPLPPPGQQVIHVTQDLDTDLEALFNSVMNPKPSS------WRKKILPESFFKEPDSG 59
Query: 103 SHSRQASTDA-----GTAGALTPQHVRAHSSPASLQLGAVSPGTLTPTGVVSGPAATPTA 157
SHSRQ+STD+ G A QHVR+HSSPASLQLG TG +G A +P
Sbjct: 60 SHSRQSSTDSSGGHPGPRLAGGAQHVRSHSSPASLQLG---------TG--AGAAGSPAQ 108
Query: 158 QH--LRQSSFEIPDDVPLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPRKAM---LSQMNV 212
QH LRQ S+++ D++PLP GWEM T++GQRYFLNHI++ TTWQDPRKAM L+ MN+
Sbjct: 109 QHAHLRQQSYDVTDELPLPPGWEMTFTATGQRYFLNHIEKITTWQDPRKAMNQPLNHMNL 168
Query: 213 -TAPTSPPVQQNMMNSAS---AMN-QRISQSAPVKQPPPLAP-QSPQGGVMGGSNS---- 262
A +S PV Q M + MN Q Q AP P Q+P G+M N+
Sbjct: 169 HPAVSSTPVPQRSMAVSQPNLVMNHQHQQQMAPSTLSQQNHPTQNPPAGLMSMPNALTTQ 228
Query: 263 -NQQQQMRLQQLQMEKERLRLKQQELLRQVRPQELALRSQLPT-LEQDGGTQNPVSSPGM 320
QQQ++RLQ++QME+ER+R++Q+EL+RQ E AL QLP E Q V+ P M
Sbjct: 229 QQQQQKLRLQRIQMERERIRMRQEELMRQ----EAALCRQLPMEAETLAPVQAAVNPPTM 284
Query: 321 SQELRTMTTNSSDPFLNSGTYHSRDESTDSGLSMSSYSVPRTPDDFLNSVDEMDTGDTIN 380
+ ++R++T NSSDPFLN G YHSR++STDSGL + YSVP TP+DFL++VDEMDTG+
Sbjct: 285 TPDMRSITNNSSDPFLNGGPYHSREQSTDSGLGLGCYSVPTTPEDFLSNVDEMDTGENAG 344
Query: 381 QS--TLPSQQNRFPDYLEAIPGTNVDLGTLEGDGMNIEGEELMPSLQEALSSDILNDMES 438
Q+ + QQ RFPD+L+ +PGTNVDLGTL E E+L+P + ND+ES
Sbjct: 345 QTPMNINPQQTRFPDFLDCLPGTNVDLGTL-------ESEDLIP---------LFNDVES 388
Query: 439 VLAATKLDKESFLTWL 454
L + E FLTWL
Sbjct: 389 ALNKS----EPFLTWL 400
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 60.5 bits (145), Expect = 3e-09
Identities = 73/267 (27%), Positives = 99/267 (37%), Gaps = 58/267 (21%)
Query: 3 PGQQPPPQPAPQGQGQPPSQPPQGQGPPSGPGQPAPAATQAAP-----QAPPAGHQIVHV 57
P QQPPP P PQ Q QPP PP PPS P Q APA + P Q P Q+
Sbjct: 760 PPQQPPPPPPPQQQQQPPPPPP----PPSMPQQAAPAMKSSPPPFIATQVPVLEPQL--- 812
Query: 58 RGDSETDLEALFNAVMNPKTANVPQTVPMRLRKLPDSFFKPPEPKSHS------------ 105
G + +++ +P +P P PP H+
Sbjct: 813 PGSVFDPIGHFTQPILHLPQPELPPHLPQ-----PPEHSTPPHLNQHAVVSPPALHNALP 867
Query: 106 RQASTDAGTAGALTPQHVRAHSSPASLQLGAVSPGTLTPTGVVSGPAATPTAQHLRQSSF 165
+Q S + A AL P+ R AVSP LT T ++ P Q L +
Sbjct: 868 QQPSRPSNRAAALPPKPARP---------PAVSP-ALTQTPLLPQPPMAQPPQVLLED-- 915
Query: 166 EIPDDVPLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPRKAMLSQMNVTAPTSPPVQQNMM 225
E P PL TS + +L + + P +L + V + PP+
Sbjct: 916 EEPPAPPL--------TSMQMQLYLQQLQKV----QPPTPLLPSVKVQSQPPPPLPPPPH 963
Query: 226 NSASAMNQRISQSAPVKQPPPLAPQSP 252
S + Q++ Q P PPP PQ P
Sbjct: 964 PS---VQQQLQQQPP--PPPPPQPQPP 985
Score = 40.0 bits (92), Expect = 0.004
Identities = 25/66 (37%), Positives = 26/66 (39%), Gaps = 12/66 (18%)
Query: 3 PGQQPPPQPAPQGQGQ---PPSQPPQGQGPPSGPGQPAPAATQAAPQ---------APPA 50
P PPP P+ Q Q Q PP PPQ Q PP QP P P PP
Sbjct: 956 PPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQ 1015
Query: 51 GHQIVH 56
G Q H
Sbjct: 1016 GQQPPH 1021
Score = 40.0 bits (92), Expect = 0.004
Identities = 25/62 (40%), Positives = 26/62 (41%), Gaps = 18/62 (29%)
Query: 3 PGQQPPPQPAPQGQGQPPSQ-----------------PPQGQGPP-SGPGQPAPAATQAA 44
P P PQP PQ Q QPP + PPQGQ PP PGQ P A
Sbjct: 976 PPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAK 1035
Query: 45 PQ 46
PQ
Sbjct: 1036 PQ 1037
Score = 33.9 bits (76), Expect = 0.31
Identities = 61/307 (19%), Positives = 111/307 (36%), Gaps = 35/307 (11%)
Query: 8 PPQPAPQGQGQPPSQPPQGQGPPSGPGQPAPAATQAAPQAPPAGHQIVH----VRGDSET 63
PPQP PP PPQ Q PP+ PAP Q+ P A Q V V+ ++T
Sbjct: 243 PPQPLQT----PPPVPPQPQPPPA----PAPQPVQSHPPIIAATPQPVKTKKGVKRKADT 294
Query: 64 DLEALFNAVMNPKT-ANVPQTVPMRLRKLPDSFFKPPE-----------PKSHSRQASTD 111
+ + P + P+T + R+ KPP+ P+ S+ +
Sbjct: 295 TTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQL 354
Query: 112 AGTAGALTPQHVRAHSS---PASLQLGAVSPGTLTPTGVVSGPAATPTAQHLRQSSFEIP 168
+G L + H++ P + + G ++ P T + + + E
Sbjct: 355 KCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKS-KLEAREYR 413
Query: 169 DDVPLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPRKAMLSQMNVTAPTSPPVQQNMMNSA 228
D A + ++ Y N D + + +M P + + S+
Sbjct: 414 DAQEFGADVRLMFSNC---YKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSS 470
Query: 229 SAMNQRISQSAPVKQPPPLAPQSPQGGVMGGSNSNQQQQMRLQQLQMEKERLRLKQQELL 288
A + V PP + S S+++ ++ R Q+L +E+L+ ++L
Sbjct: 471 PA----VPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLA 526
Query: 289 RQVRPQE 295
+PQ+
Sbjct: 527 ALSQPQQ 533
Score = 30.0 bits (66), Expect = 4.5
Identities = 24/113 (21%), Positives = 52/113 (46%), Gaps = 5/113 (4%)
Query: 203 RKAMLSQMNVTAPTSPPVQQNMMNSASAMNQRISQSAPVKQPPPLAPQSPQGGVMGGSNS 262
RK + + + PP ++ N++S N + AP+K PP +S + +
Sbjct: 553 RKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSY 612
Query: 263 NQQQQMRLQQLQMEKERLRLKQQELLRQVRPQELALRSQLP-TLEQDGGTQNP 314
+++Q+ L ++ E+L ++ ++ +E +L++ P +E D T P
Sbjct: 613 EEKRQLSLDINKLPGEKL----GRVVHIIQSREPSLKNSNPDEIEIDFETLKP 661
Score = 30.0 bits (66), Expect = 4.5
Identities = 18/45 (40%), Positives = 18/45 (40%), Gaps = 1/45 (2%)
Query: 5 QQPPPQPAPQGQGQPPSQPPQGQGPPSGPGQPAPAATQAAPQAPP 49
Q PP P P Q Q Q PP P QP P Q Q PP
Sbjct: 951 QSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQP-PPQQQHQPPP 994
>gi|56549696 E1A binding protein p400 [Homo sapiens]
Length = 3122
Score = 57.4 bits (137), Expect = 3e-08
Identities = 84/323 (26%), Positives = 124/323 (38%), Gaps = 64/323 (19%)
Query: 5 QQPPPQPAPQGQGQPPSQPPQGQGPPSGPGQPAPAATQAAPQAPPAGHQIVHVRGDSETD 64
QQ QPA QPP PQ PP P P P QAA PPAG V
Sbjct: 2495 QQKAQQPAV---AQPPPPQPQPPPPPQQPPPPLPQP-QAAGSQPPAGPPAVQ-------- 2542
Query: 65 LEALFNAVMNPKTANVPQTVPMRLRKLPDSFFKPPEPKSHSRQASTDAGTAGALTPQHVR 124
P+ PQT P +P + + ++ A T G+A L ++
Sbjct: 2543 ----------PQPQPQPQTQP-----------QPVQAPAKAQPAITTGGSAAVLAGT-IK 2580
Query: 125 AHSSPASLQLGAVSPGTLTPTGVVSGPAATPTAQHLRQSSFEIPDDVPLPAGWEMAKTSS 184
+ S+ GAVS + T + PAAT + + R +S P + P G A
Sbjct: 2581 TSVTGTSMPTGAVSGNVIVNT-IAGVPAATFQSINKRLASPVAPGALTTPGGSAPA---- 2635
Query: 185 GQRYFLNHIDQTTTWQDPRKAMLSQMNVTAP-TSPPVQQNM--MNSASAMNQRISQSAPV 241
Q Q P +A+ S T S Q + + S +A + PV
Sbjct: 2636 ----------QVVHTQPPPRAVGSPATATPDLVSMATTQGVRAVTSVTASAVVTTNLTPV 2685
Query: 242 KQPP-PLAPQSPQ--GGVMGGSNSN-------QQQQMRLQQLQMEKERLRLKQQELLRQV 291
+ P L PQ Q G + G +QQQ + QQ Q ++++ + +QQ+ +Q
Sbjct: 2686 QTPARSLVPQVSQATGVQLPGKTITPAHFQLLRQQQQQQQQQQQQQQQQQQQQQQ--QQQ 2743
Query: 292 RPQELALRSQLPTLEQDGGTQNP 314
+ Q+ SQ+ + G Q+P
Sbjct: 2744 QQQQTTTTSQVQVPQIQGQAQSP 2766
Score = 51.6 bits (122), Expect = 1e-06
Identities = 75/312 (24%), Positives = 104/312 (33%), Gaps = 54/312 (17%)
Query: 3 PGQQPPPQPAPQGQG------------QPPSQPPQGQGPPSGPGQPAPAATQAAPQAPPA 50
P Q PPP P PQ G QP QP P P + PA T A A
Sbjct: 2517 PQQPPPPLPQPQAAGSQPPAGPPAVQPQPQPQPQTQPQPVQAPAKAQPAITTGGSAAVLA 2576
Query: 51 GHQIVHVRGDSETDLEALFNAVMNPKTANVP----QTVPMRLRK--LPDSFFKP------ 98
G V G S N ++N A VP Q++ RL P + P
Sbjct: 2577 GTIKTSVTGTSMPTGAVSGNVIVN-TIAGVPAATFQSINKRLASPVAPGALTTPGGSAPA 2635
Query: 99 ------PEPKSHSRQASTDAGTAGALTPQHVRAHSSPASLQLGAVSPGTLTPTGVVSGPA 152
P P++ A+ T Q VRA S+ AV LTP V PA
Sbjct: 2636 QVVHTQPPPRAVGSPATATPDLVSMATTQGVRA---VTSVTASAVVTTNLTP---VQTPA 2689
Query: 153 ATPTAQHLRQSSFEIPDDVPLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPRKAMLSQM-N 211
+ Q + + ++P PA +++ + Q+ Q Q ++ Q
Sbjct: 2690 RSLVPQVSQATGVQLPGKTITPAHFQLLRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTT 2749
Query: 212 VTAPTSPPVQQNMMNSASAMN-------------QRISQSAPVKQPPP---LAPQSPQGG 255
T+ P Q S + + Q+ P + PPP AP P
Sbjct: 2750 TTSQVQVPQIQGQAQSPAQIKAVGKLTPEHLIKMQKQKLQMPPQPPPPQAQSAPPQPTAQ 2809
Query: 256 VMGGSNSNQQQQ 267
V ++ QQQ
Sbjct: 2810 VQVQTSQPPQQQ 2821
Score = 35.4 bits (80), Expect = 0.11
Identities = 60/271 (22%), Positives = 84/271 (30%), Gaps = 54/271 (19%)
Query: 3 PGQQPPPQPAPQGQGQPPSQPPQGQGP-------PSGPGQPAPAATQAAPQAPPAGHQIV 55
P PP AP P P +G+ P P AP T A + P HQ
Sbjct: 1444 PSTHPPRTAAPTTASAAPQGPLRGRPPIATFSANPEAKAAAAPFQTSQASASAPR-HQPA 1502
Query: 56 HVRGDSETDLEALFNAVMNPKTANVPQTVPMRLRKLPDSFFKPPEPKSHSRQASTDAGTA 115
S T A + +T T PP+P++ S A A
Sbjct: 1503 SA---SSTAASPAHPAKLRAQTTAQASTPGQ----------PPPQPQAPSHAAGQSALPQ 1549
Query: 116 GALTPQHVRAHSSPASLQLGAVSPGTLTPTGVVSGPAATPTAQHLRQSSFEIPDDVPLPA 175
+ P +A + A P V+ P T Q
Sbjct: 1550 RLVLPSQAQARLPSGEVVKIAQLASITGPQSRVAQPETPVTLQF---------------- 1593
Query: 176 GWEMAKTSSGQRYFLNH--IDQTTTWQDPRKAMLSQMNVTAPTSP------PVQQNMMNS 227
G ++ L+H + Q T Q + V+AP P PV ++
Sbjct: 1594 --------QGSKFTLSHSQLRQLTAGQPLQLQGSVLQIVSAPGQPYLRAPGPVVMQTVSQ 1645
Query: 228 ASAMNQRISQSAPVKQPPPLAPQSPQGGVMG 258
A A++ + P P P AP +PQ GV G
Sbjct: 1646 AGAVHGALGSKPPAGGPSP-APLTPQVGVPG 1675
Score = 31.2 bits (69), Expect = 2.0
Identities = 36/134 (26%), Positives = 55/134 (41%), Gaps = 13/134 (9%)
Query: 11 PAPQGQGQPPSQPPQGQGPPSGPGQPAPAATQAAPQAPPAGHQIVHVRGDSETDLEALFN 70
P +G+ QP P PPS AP+A+ +APQ+P +QI + S + + N
Sbjct: 21 PGSEGEEQPAHPNP----PPSPAAPFAPSASPSAPQSP--SYQIQQLMNRSPATGQNV-N 73
Query: 71 AVMNPKTANVPQTVPMRLRKLPDSFFKPPEPKSHSRQASTDAGTAGALTPQHVRAHSSPA 130
+ V + L LP P P S Q S +P +++ +SP
Sbjct: 74 ITLQSVGPVVGGNQQITLAPLP-----LPSPTSPGFQFSAQPRRFEHGSPSYIQV-TSPL 127
Query: 131 SLQLGAVSPGTLTP 144
S Q+ SP +P
Sbjct: 128 SQQVQTQSPTQPSP 141
>gi|40806207 WW domain containing E3 ubiquitin protein ligase 2
isoform 1 [Homo sapiens]
Length = 870
Score = 54.7 bits (130), Expect = 2e-07
Identities = 58/213 (27%), Positives = 86/213 (40%), Gaps = 33/213 (15%)
Query: 11 PAPQGQGQP-PSQPPQGQGPPSGPGQPAPAATQAAPQAPPAGHQIVHVRGDSETDLEALF 69
P P P P+ P +G+ P + Q PAA QA P A PAG + E ++
Sbjct: 265 PNPNTTSLPAPATPAEGEEPSTSGTQQLPAAAQA-PDALPAGWE------QRELPNGRVY 317
Query: 70 NAVMNPKTANVPQTVPMRLRKLPDSFFKPPEPKSHSRQASTDAGTAGALTPQHVRAHSSP 129
N KT + +P K D P + + +T T T ++VR +
Sbjct: 318 YVDHNTKTTTWERPLPPGWEKRTD-----PRGRFYYVDHNTRTTTWQRPTAEYVRNYEQW 372
Query: 130 ASLQLGAVSPGTLTPTGVVSGPAATPTAQHLRQSSFEIPDDVPL---PAGWEMAKTSSGQ 186
S + + G + + L QSS D PL P GWE + +G+
Sbjct: 373 QSQR------------NQLQGAMQHFSQRFLYQSSSASTDHDPLGPLPPGWEK-RQDNGR 419
Query: 187 RYFLNHIDQTTTWQDPRKAMLSQMNVTAPTSPP 219
Y++NH +TT W+DPR +Q + P PP
Sbjct: 420 VYYVNHNTRTTQWEDPR----TQGMIQEPALPP 448
Score = 47.0 bits (110), Expect = 4e-05
Identities = 52/195 (26%), Positives = 77/195 (39%), Gaps = 11/195 (5%)
Query: 12 APQGQGQPPSQPPQGQGPPSGPGQPAPAATQAAPQAPPAGHQIVHVRGDSETDLEALFNA 71
AP+ + QPPS G + A A T A G + H + + L N
Sbjct: 174 APENRHQPPSTNCFGGRSRTHRHSGASARTTPATGEQSPGARSRHRQPVKNSGHSGLANG 233
Query: 72 VMN--PKTANVPQTVPMRLRKLPDSFFKPPEPKSHSRQASTDAGTAGALTPQHVRAHSSP 129
+N P TA P+ + P P P S + +T + A A TP S+
Sbjct: 234 TVNDEPTTATDPEEPSVVGVTSP-----PAAPLSVTPNPNTTSLPAPA-TPAEGEEPSTS 287
Query: 130 ASLQLGAVS--PGTLTPTGVVSGPAATPTAQHLRQSSFEIPDDVPLPAGWEMAKTSSGQR 187
+ QL A + P L P G ++ ++ + PLP GWE G+
Sbjct: 288 GTQQLPAAAQAPDAL-PAGWEQRELPNGRVYYVDHNTKTTTWERPLPPGWEKRTDPRGRF 346
Query: 188 YFLNHIDQTTTWQDP 202
Y+++H +TTTWQ P
Sbjct: 347 YYVDHNTRTTTWQRP 361
>gi|156071470 hyperpolarization activated cyclic nucleotide-gated
potassium channel 2 [Homo sapiens]
Length = 889
Score = 52.0 bits (123), Expect = 1e-06
Identities = 49/154 (31%), Positives = 56/154 (36%), Gaps = 26/154 (16%)
Query: 3 PGQQPPPQPAPQGQGQPPSQPPQGQGPPSGPGQPAPAATQAAPQAPPAGHQIVHVRGDSE 62
PG+ P PAP PP PPQ Q PP P P P A PQ PP
Sbjct: 10 PGESPGATPAPGPPPPPPPAPPQQQPPPPPPPAPPPGPGPAPPQHPPRA----------- 58
Query: 63 TDLEALFNAVMNPKTANVPQTVPMRLRKLPDSFFKPPEPKSHSRQASTDAGTAGALTPQH 122
EAL P A RLR S +P P + S + G G PQ
Sbjct: 59 ---EAL------PPEAADEGGPRGRLRSRDSSCGRPGTPGAASTAKGSPNGECGRGEPQ- 108
Query: 123 VRAHSSPASLQLGAVSPG-TLTPTGVVSGPAATP 155
SPA + A P + + G SGPA P
Sbjct: 109 ----CSPAGPEGPARGPKVSFSCRGAASGPAPGP 138
Score = 41.6 bits (96), Expect = 0.001
Identities = 33/123 (26%), Positives = 45/123 (36%), Gaps = 9/123 (7%)
Query: 5 QQPPPQPAPQGQGQPPSQPPQGQGPPSGPGQPAPAATQAAPQAPPAG-----HQIVHVRG 59
++PPP PAP P P G P+ P P + P AP AG ++
Sbjct: 759 RRPPPGPAPAAASPGPPPPASPPGAPASPRAPRTSPYGGLPAAPLAGPALPARRLSRASR 818
Query: 60 DSETDLEALFNAVMNPKTANVP-QTVPMRLRKLPDSFFKPPEPKSHSRQASTDAGTAGAL 118
+L + P + P + RL P + P P R+ S G AG L
Sbjct: 819 PLSASQPSLPHGAPGPAASTRPASSSTPRLGPTPAARAAAPSP---DRRDSASPGAAGGL 875
Query: 119 TPQ 121
PQ
Sbjct: 876 DPQ 878
Score = 30.8 bits (68), Expect = 2.6
Identities = 22/71 (30%), Positives = 31/71 (43%), Gaps = 8/71 (11%)
Query: 9 PQPAPQGQGQPPSQPPQG---QGPPSGPGQ-PAPAATQAAPQAPPAGHQIVHVRGDSETD 64
PQ +P G P P +G SGP P PA + +A PAG RG +
Sbjct: 107 PQCSPAGPEGPARGPKVSFSCRGAASGPAPGPGPAEEAGSEEAGPAGEP----RGSQASF 162
Query: 65 LEALFNAVMNP 75
++ F A++ P
Sbjct: 163 MQRQFGALLQP 173
Score = 29.6 bits (65), Expect = 5.9
Identities = 17/45 (37%), Positives = 21/45 (46%), Gaps = 3/45 (6%)
Query: 9 PQPAPQGQGQPP--SQPPQGQGP-PSGPGQPAPAATQAAPQAPPA 50
P P G P +PP G P + PG P PA+ AP +P A
Sbjct: 745 PLVGPLALGSPRLVRRPPPGPAPAAASPGPPPPASPPGAPASPRA 789
>gi|110431370 espin [Homo sapiens]
Length = 854
Score = 51.6 bits (122), Expect = 1e-06
Identities = 81/379 (21%), Positives = 133/379 (35%), Gaps = 86/379 (22%)
Query: 4 GQQPPPQPAPQGQGQPPSQPPQGQGPPSGPGQPAPAATQAAPQAPPAGHQIVHVRGDSET 63
G+ PP P P PP PP Q PP PG PAP PP G Q + ++
Sbjct: 426 GKPTPPPPPPSFP--PPPPPPGTQLPPPPPGYPAP--------KPPVGPQAADIYMQTKN 475
Query: 64 DLEALFNAVMNPKTANVPQTVPMRLR---KLPDSFFKPPEPKSHSRQ-----ASTDAGTA 115
L + + + ++ +R + + P +F K P + RQ T A
Sbjct: 476 KLRHVETEALKKELSSCDGHDGLRRQDSSRKPRAFSKQPSTGDYYRQLGRCPGETLAARP 535
Query: 116 GALTPQHVRAH------------------SSPASLQLGAVSPGTLTPTGVVSGPAAT--- 154
G + VRA P++ A+ PG P G + P A+
Sbjct: 536 GMAHSEEVRARQPARAGCPRLGPAARGSLEGPSAPPQAALLPGNHVPNGCAADPKASREL 595
Query: 155 -----PTAQHLRQSSFEIPDDVPLPAGWEMAKTSSGQRYFLNHIDQTTTWQ-----DPRK 204
P L +++ P PLP E A GQR + T ++
Sbjct: 596 PPPPPPPPPPLPEAASSPPPAPPLPL--ESAGPGCGQRRSSSSTGSTKSFNMMSPTGDNS 653
Query: 205 AMLSQMNVTAPTSP-PVQQNMMNSASAMNQRISQS-----------APVKQPPPLA---- 248
+L+++ P P + + S + Q Q +PV+ P P A
Sbjct: 654 ELLAEIKAGKSLKPTPQSKGLTTVFSGIGQPAFQPDSPLPSVSPALSPVRSPTPPAAGFQ 713
Query: 249 -----------PQSPQGGVMGGSNS---NQQQQMR-----LQQLQMEKERLRLKQQELLR 289
P +P GV + +Q R +Q+ + K +L+++++E R
Sbjct: 714 PLLNGSLVPVPPTTPAPGVQLDVEALIPTHDEQGRPIPEWKRQVMVRKMQLKMQEEEEQR 773
Query: 290 QVRPQELALRSQLPTLEQD 308
+ +E A + +P +D
Sbjct: 774 RKEEEEEARLASMPAWRRD 792
Score = 30.4 bits (67), Expect = 3.5
Identities = 13/35 (37%), Positives = 16/35 (45%), Gaps = 3/35 (8%)
Query: 1 MDPGQQPPPQPAPQGQGQPPSQPP---QGQGPPSG 32
+ P PPP P P+ PP PP + GP G
Sbjct: 595 LPPPPPPPPPPLPEAASSPPPAPPLPLESAGPGCG 629
>gi|66346708 membrane associated guanylate kinase, WW and PDZ domain
containing 1 isoform b [Homo sapiens]
Length = 1256
Score = 51.6 bits (122), Expect = 1e-06
Identities = 69/326 (21%), Positives = 137/326 (42%), Gaps = 46/326 (14%)
Query: 145 TGVVSGPAATPTAQHLRQSSFEIPDDV-PLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPR 203
+ +++ P P+ + + D++ PLP WEMA T +G+ YF++H +TT+W DPR
Sbjct: 273 SSIIAAPITDPSQKFPQYLPLSAEDNLGPLPENWEMAYTENGEVYFIDHNTKTTSWLDPR 332
Query: 204 KAMLSQMNVTAPTSPPVQQNMMNSASAMNQRISQSAPVKQPPPLAPQSPQGGVMGGSNSN 263
+N + + ++ + A ++ + P G+ + N
Sbjct: 333 -----CLNKQQKPLEECEDDEGVHTEELDSELELPAGWEK-----IEDPVYGIYYVDHIN 382
Query: 264 QQQQMRLQQLQME-KERLRLKQQELLRQVRPQELALRSQLPTLEQDGGT-------QNPV 315
++ Q L+ + K++L +QQ+ +Q + Q+ + Q +D +P
Sbjct: 383 RKTQYENPVLEAKRKKQLEQQQQQQQQQQQQQQQQQQQQTEEWTEDHSALVPPVIPNHPP 442
Query: 316 SSPGMSQELRT-----MTTNSSDPFLNSGTYHSRDESTDSGLSMSSYSVPRTPDDFLN-- 368
S+P ++E+ T N S+ L H++ + G + PD+FL
Sbjct: 443 SNPEPAREVPLQGKPFFTRNPSE--LKGKFIHTKLRKSSRGFGFTVVGGDE-PDEFLQIK 499
Query: 369 --------SVD-EMDTGDTI----NQSTLPSQQNRFPDYLEAIP-GTNVDLGTLEGDGMN 414
++D +M+TGD I + L + ++IP G +VDL G +
Sbjct: 500 SLVLDGPAALDGKMETGDVIVSVNDTCVLGHTHAQVVKIFQSIPIGASVDLELCRGYPLP 559
Query: 415 IEGEELMPSLQEALSSDILNDMESVL 440
+ ++ SL ++S + D E ++
Sbjct: 560 FDPDDPNTSL---VTSVAILDKEPII 582
>gi|74272284 membrane associated guanylate kinase, WW and PDZ domain
containing 1 isoform c [Homo sapiens]
Length = 1462
Score = 51.6 bits (122), Expect = 1e-06
Identities = 69/326 (21%), Positives = 137/326 (42%), Gaps = 46/326 (14%)
Query: 145 TGVVSGPAATPTAQHLRQSSFEIPDDV-PLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPR 203
+ +++ P P+ + + D++ PLP WEMA T +G+ YF++H +TT+W DPR
Sbjct: 273 SSIIAAPITDPSQKFPQYLPLSAEDNLGPLPENWEMAYTENGEVYFIDHNTKTTSWLDPR 332
Query: 204 KAMLSQMNVTAPTSPPVQQNMMNSASAMNQRISQSAPVKQPPPLAPQSPQGGVMGGSNSN 263
+N + + ++ + A ++ + P G+ + N
Sbjct: 333 -----CLNKQQKPLEECEDDEGVHTEELDSELELPAGWEK-----IEDPVYGIYYVDHIN 382
Query: 264 QQQQMRLQQLQME-KERLRLKQQELLRQVRPQELALRSQLPTLEQDGGT-------QNPV 315
++ Q L+ + K++L +QQ+ +Q + Q+ + Q +D +P
Sbjct: 383 RKTQYENPVLEAKRKKQLEQQQQQQQQQQQQQQQQQQQQTEEWTEDHSALVPPVIPNHPP 442
Query: 316 SSPGMSQELRT-----MTTNSSDPFLNSGTYHSRDESTDSGLSMSSYSVPRTPDDFLN-- 368
S+P ++E+ T N S+ L H++ + G + PD+FL
Sbjct: 443 SNPEPAREVPLQGKPFFTRNPSE--LKGKFIHTKLRKSSRGFGFTVVGGDE-PDEFLQIK 499
Query: 369 --------SVD-EMDTGDTI----NQSTLPSQQNRFPDYLEAIP-GTNVDLGTLEGDGMN 414
++D +M+TGD I + L + ++IP G +VDL G +
Sbjct: 500 SLVLDGPAALDGKMETGDVIVSVNDTCVLGHTHAQVVKIFQSIPIGASVDLELCRGYPLP 559
Query: 415 IEGEELMPSLQEALSSDILNDMESVL 440
+ ++ SL ++S + D E ++
Sbjct: 560 FDPDDPNTSL---VTSVAILDKEPII 582
>gi|74272282 membrane associated guanylate kinase, WW and PDZ domain
containing 1 isoform a [Homo sapiens]
Length = 1287
Score = 51.6 bits (122), Expect = 1e-06
Identities = 69/326 (21%), Positives = 137/326 (42%), Gaps = 46/326 (14%)
Query: 145 TGVVSGPAATPTAQHLRQSSFEIPDDV-PLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPR 203
+ +++ P P+ + + D++ PLP WEMA T +G+ YF++H +TT+W DPR
Sbjct: 273 SSIIAAPITDPSQKFPQYLPLSAEDNLGPLPENWEMAYTENGEVYFIDHNTKTTSWLDPR 332
Query: 204 KAMLSQMNVTAPTSPPVQQNMMNSASAMNQRISQSAPVKQPPPLAPQSPQGGVMGGSNSN 263
+N + + ++ + A ++ + P G+ + N
Sbjct: 333 -----CLNKQQKPLEECEDDEGVHTEELDSELELPAGWEK-----IEDPVYGIYYVDHIN 382
Query: 264 QQQQMRLQQLQME-KERLRLKQQELLRQVRPQELALRSQLPTLEQDGGT-------QNPV 315
++ Q L+ + K++L +QQ+ +Q + Q+ + Q +D +P
Sbjct: 383 RKTQYENPVLEAKRKKQLEQQQQQQQQQQQQQQQQQQQQTEEWTEDHSALVPPVIPNHPP 442
Query: 316 SSPGMSQELRT-----MTTNSSDPFLNSGTYHSRDESTDSGLSMSSYSVPRTPDDFLN-- 368
S+P ++E+ T N S+ L H++ + G + PD+FL
Sbjct: 443 SNPEPAREVPLQGKPFFTRNPSE--LKGKFIHTKLRKSSRGFGFTVVGGDE-PDEFLQIK 499
Query: 369 --------SVD-EMDTGDTI----NQSTLPSQQNRFPDYLEAIP-GTNVDLGTLEGDGMN 414
++D +M+TGD I + L + ++IP G +VDL G +
Sbjct: 500 SLVLDGPAALDGKMETGDVIVSVNDTCVLGHTHAQVVKIFQSIPIGASVDLELCRGYPLP 559
Query: 415 IEGEELMPSLQEALSSDILNDMESVL 440
+ ++ SL ++S + D E ++
Sbjct: 560 FDPDDPNTSL---VTSVAILDKEPII 582
>gi|31317292 Smad ubiquitination regulatory factor 1 isoform 1 [Homo
sapiens]
Length = 757
Score = 50.8 bits (120), Expect = 2e-06
Identities = 94/430 (21%), Positives = 154/430 (35%), Gaps = 85/430 (19%)
Query: 31 SGPGQPA------PAATQAAPQAPPAGHQIVHVRGDSETDLEALFNAVMNPKTANVPQTV 84
SGPG+P PA + A G V S+ D + NP QT
Sbjct: 166 SGPGRPLSCFMEEPAPYTDSTGAAAGGGNCRFVESPSQ-DQRLQAQRLRNPDVRGSLQTP 224
Query: 85 PMRLRKLPDSFFKPPEPKSHSRQASTDAGTAGALTPQHVRAHSSPASLQLGAVSPGTLTP 144
R P P P+ + ++ + T V P +P
Sbjct: 225 QNR----PHGHQSPELPEGYEQRTTVQGQVYFLHTQTGVSTWHDPR----------IPSP 270
Query: 145 TGVVSGPAATPTAQHLRQSSFEIPDDV---------PLPAGWEMAKTSSGQRYFLNHIDQ 195
+G + G A + L Q P D+ PLP GWE+ T SG+ YF++H ++
Sbjct: 271 SGTIPGGDAAFLYEFLLQGHTSEPRDLNSVNCDELGPLPPGWEVRSTVSGRIYFVDHNNR 330
Query: 196 TTTWQDPR--KAMLSQMNVTAPTSP-PV-QQNMMNSASAMNQRISQSAPVKQPPPLAPQS 251
TT + DPR M Q + P+ P P+ + + QR + K
Sbjct: 331 TTQFTDPRLHHIMNHQCQLKEPSQPLPLPSEGSLEDEELPAQRYERDLVQKLK------- 383
Query: 252 PQGGVMGGSNSNQQQQMRLQQLQMEKERLRLKQQELLRQVRPQELALRSQLPTLEQDGGT 311
V+ S QQ Q ++++ +E + + + ++RP++L R + ++G
Sbjct: 384 ----VLRHELSLQQPQAGHCRIEVSREEIFEESYRQIMKMRPKDLKKRLMVKFRGEEG-- 437
Query: 312 QNPVSSPGMSQE-LRTMTTNSSDPFLNSGTYHSRDESTDSGLSMSSYSVPRTPDDFLNSV 370
+ G+++E L + +P+ Y STD + Y + PD +N
Sbjct: 438 ---LDYGGVAREWLYLLCHEMLNPYYGLFQY-----STD-----NIYMLQINPDSSIN-- 482
Query: 371 DEMDTGDTINQSTLPSQQNRFPDYLEAIPGTNVDLGTLEGDGMNIEGEELMPSLQEALSS 430
PD+L +G G I G +P ++ L
Sbjct: 483 ---------------------PDHLSYFHFVGRIMGLAVFHGHYINGGFTVPFYKQLLGK 521
Query: 431 DI-LNDMESV 439
I L+D+ESV
Sbjct: 522 PIQLSDLESV 531
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 50.1 bits (118), Expect = 4e-06
Identities = 86/362 (23%), Positives = 125/362 (34%), Gaps = 59/362 (16%)
Query: 3 PGQQPPPQPAP--QGQGQPP------------SQPPQGQGPPSGPGQPAPAATQAAPQAP 48
P QQ PP+P P QG G+ P QP + + P G G+P Q Q P
Sbjct: 210 PLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKP----IQGPTQTP 265
Query: 49 PAGHQIVHVRGDS------ETDL---EALFNAVMNPKTANVPQTVPMRLRKLPDSFFKPP 99
H + ++ D+ + D+ E++ ++ +P + Q P K P +P
Sbjct: 266 QTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTP---GKPPAQ--QPG 320
Query: 100 EPKSHSRQASTDAGTAGALTPQHVRAHSSPASLQLGAVSPGTLTPTGVVSGPAATPTAQ- 158
KS A A +G P P +++ PGT P GPA P Q
Sbjct: 321 HEKSQPGPAKPPAQPSGLTKP----LAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQT 376
Query: 159 HLRQSSFEIPDDVPLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPRKAMLSQMNVTAPTSP 218
+ S E P L + KT + Q P A V P
Sbjct: 377 GSEKPSSEQPGPKALAQPPGVGKTPA---------------QQPGPAKPPTQQVGTPKPL 421
Query: 219 PVQQNMMNSASAMNQRISQSAPVKQPPPLAPQSPQGGVMGGSNSNQQQQMRLQQLQMEKE 278
Q + + A A PV+QP P + Q G G S QQ Q+
Sbjct: 422 AQQPGLQSPAKAPG---PTKTPVQQPGPGKIPAQQAG--PGKTSAQQTGPTKPPSQLPGP 476
Query: 279 RLRLKQQELLRQVRPQELALRSQLPTLEQDGGTQNPVSSPGMSQELRTMTTNSSDPFLNS 338
QQ + PQ+ S P +Q G T+ P PG ++ ++ P
Sbjct: 477 AKPPPQQPGPAKPPPQQPG--SAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQP 534
Query: 339 GT 340
G+
Sbjct: 535 GS 536
Score = 44.7 bits (104), Expect = 2e-04
Identities = 98/504 (19%), Positives = 171/504 (33%), Gaps = 76/504 (15%)
Query: 3 PGQQPPPQP-APQGQGQPPSQPPQGQGPPSGPGQPAPAATQAAP----QAPPAGHQIVHV 57
PG P AP Q PSQPP QGPP GQ PA ++ P PA ++
Sbjct: 952 PGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPK 1011
Query: 58 RGDSETDLEALFNAVMNPKTANVPQTVPMRLRKLPDSFFKPPEPKSHSRQASTDAGTAGA 117
+ T P + T + LP K P+P+S T+ G+
Sbjct: 1012 AEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTEL-NIGS 1070
Query: 118 LTPQHVRAHSS--------------------------------PASLQLGAVSPGTLTPT 145
P + + S QLG + P+
Sbjct: 1071 KDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPS 1130
Query: 146 GVVSGPAATPTAQHLRQSSFEIPDDVPLPAGWEMAKTSSGQRYFLNHIDQT--------- 196
G + P PT ++++ +P V L E + ++ L + +T
Sbjct: 1131 GPKASPMPVPTESSSQKTA--VPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPM 1188
Query: 197 -TTWQDPRKAMLSQMNVTA-PTSPPVQQNMMNSASAMNQRISQSAPVKQPPPLAPQSPQG 254
TT Q ++ L + +A P+ + R + P+ + P+ +
Sbjct: 1189 VTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKK- 1247
Query: 255 GVMGGSNSNQQQQMRLQQLQMEKERLRLKQQELLRQVRPQELALRSQLPTLEQDGGTQNP 314
++ + ++ ++ Q+ + K ++++ +++L +V P+ + Q T + + P
Sbjct: 1248 -LLPEAKTSAPEE---QKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTP 1303
Query: 315 VSSPGMSQELRTMTTNSSDPFLNSGTYH-----SRDESTDSGLSMSSYSVPRTPDDFLNS 369
S P + P + + E D SS P++P
Sbjct: 1304 QSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGL--- 1360
Query: 370 VDEMDTGDTINQSTLPSQQNRFPDYLEAIPGTNVD-LGTLEGDGMNIEGEELMPSLQEAL 428
DTG + + S P IP D L L+ D + E PS L
Sbjct: 1361 ---SDTG--YSSDGISSSLGEIP---SLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKL 1412
Query: 429 SSDILNDME---SVLAATKLDKES 449
S +L+ +E S LA K +K++
Sbjct: 1413 ESTVLSILEAQASTLADEKSEKKT 1436
Score = 39.7 bits (91), Expect = 0.006
Identities = 47/182 (25%), Positives = 58/182 (31%), Gaps = 29/182 (15%)
Query: 1 MDPGQQPPPQPAPQGQGQPPSQPPQGQGPPSGPGQPAPAATQAAPQAPPAGHQIVHVRGD 60
+D QPPP P P PP PP PP P P P T P P V
Sbjct: 2399 LDISAQPPPPPPP----PPPPPPP----PPPPPPPPLPPPTSPKPTILPKKKLTV---AS 2447
Query: 61 SETDLEALFNAVMNPKTANV---------------PQTVPMRLRKLPDS--FFKPPEPKS 103
T LF+AV +T V P VP + +P F PEP
Sbjct: 2448 PVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSK 2507
Query: 104 HSRQASTDAGTAGALTPQHVRAHSSPASLQLGAVSPGTLTPTGVVSGPAAT-PTAQHLRQ 162
T + H P L L + L + P+ T P + H +
Sbjct: 2508 PPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNK 2567
Query: 163 SS 164
SS
Sbjct: 2568 SS 2569
Score = 35.4 bits (80), Expect = 0.11
Identities = 23/58 (39%), Positives = 25/58 (43%), Gaps = 10/58 (17%)
Query: 3 PGQQPPPQPAPQGQGQPPSQP------PQGQG---PPS-GPGQPAPAATQAAPQAPPA 50
PG PP P PP QP PQ G PPS PG P+A Q +P P A
Sbjct: 494 PGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSA 551
Score = 35.0 bits (79), Expect = 0.14
Identities = 23/50 (46%), Positives = 27/50 (54%), Gaps = 5/50 (10%)
Query: 3 PGQQP-PPQPAPQ--GQGQPPSQPPQGQGPPSGPGQPAPAATQAAPQAPP 49
P QQP P +P+PQ G +PPSQ P G PS QP+PA A P
Sbjct: 510 PPQQPGPAKPSPQQPGSTKPPSQQP-GSAKPSAQ-QPSPAKPSAQQSTKP 557
Score = 34.7 bits (78), Expect = 0.18
Identities = 67/272 (24%), Positives = 92/272 (33%), Gaps = 47/272 (17%)
Query: 6 QPPPQPA--------PQGQGQPPSQPPQGQGPPSGPGQPA-PAATQAAPQAP----PAGH 52
+PP QP+ G +PP QPP PP+ P PA P A Q + P P
Sbjct: 330 KPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPK 389
Query: 53 QIVHVRGDSETDLEALFNAVMNPKTANVPQTVPMRLR-------KLPDSFFKPPEPKSHS 105
+ G +T + A P T V P+ + K P P +
Sbjct: 390 ALAQPPGVGKTPAQQPGPA--KPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPG 447
Query: 106 RQASTDAGTAGALTPQHVRAHSSPASLQLGAVSPGTLTPTGVVSGPAATPTAQ--HLRQS 163
+ + AG G + Q P+ L PG P GPA P Q +
Sbjct: 448 KIPAQQAG-PGKTSAQQTGPTKPPSQL------PGPAKPPPQQPGPAKPPPQQPGSAKPP 500
Query: 164 SFEIPDDVPLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPRKAMLSQMNVTAPTSPPVQQN 223
S + P P AK S Q Q P A S +P P QQ+
Sbjct: 501 SQQPGSTKPPPQQPGPAKPSPQQPG-----STKPPSQQPGSAKPSAQQ-PSPAKPSAQQS 554
Query: 224 MMNSASAMNQRISQSAPVK--QPPPLAPQSPQ 253
+ +SQ+ K QPP ++P + Q
Sbjct: 555 --------TKPVSQTGSGKPLQPPTVSPSAKQ 578
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 50.1 bits (118), Expect = 4e-06
Identities = 86/362 (23%), Positives = 125/362 (34%), Gaps = 59/362 (16%)
Query: 3 PGQQPPPQPAP--QGQGQPP------------SQPPQGQGPPSGPGQPAPAATQAAPQAP 48
P QQ PP+P P QG G+ P QP + + P G G+P Q Q P
Sbjct: 210 PLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKP----IQGPTQTP 265
Query: 49 PAGHQIVHVRGDS------ETDL---EALFNAVMNPKTANVPQTVPMRLRKLPDSFFKPP 99
H + ++ D+ + D+ E++ ++ +P + Q P K P +P
Sbjct: 266 QTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTP---GKPPAQ--QPG 320
Query: 100 EPKSHSRQASTDAGTAGALTPQHVRAHSSPASLQLGAVSPGTLTPTGVVSGPAATPTAQ- 158
KS A A +G P P +++ PGT P GPA P Q
Sbjct: 321 HEKSQPGPAKPPAQPSGLTKP----LAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQT 376
Query: 159 HLRQSSFEIPDDVPLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPRKAMLSQMNVTAPTSP 218
+ S E P L + KT + Q P A V P
Sbjct: 377 GSEKPSSEQPGPKALAQPPGVGKTPA---------------QQPGPAKPPTQQVGTPKPL 421
Query: 219 PVQQNMMNSASAMNQRISQSAPVKQPPPLAPQSPQGGVMGGSNSNQQQQMRLQQLQMEKE 278
Q + + A A PV+QP P + Q G G S QQ Q+
Sbjct: 422 AQQPGLQSPAKAPG---PTKTPVQQPGPGKIPAQQAG--PGKTSAQQTGPTKPPSQLPGP 476
Query: 279 RLRLKQQELLRQVRPQELALRSQLPTLEQDGGTQNPVSSPGMSQELRTMTTNSSDPFLNS 338
QQ + PQ+ S P +Q G T+ P PG ++ ++ P
Sbjct: 477 AKPPPQQPGPAKPPPQQPG--SAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQP 534
Query: 339 GT 340
G+
Sbjct: 535 GS 536
Score = 44.7 bits (104), Expect = 2e-04
Identities = 98/504 (19%), Positives = 171/504 (33%), Gaps = 76/504 (15%)
Query: 3 PGQQPPPQP-APQGQGQPPSQPPQGQGPPSGPGQPAPAATQAAP----QAPPAGHQIVHV 57
PG P AP Q PSQPP QGPP GQ PA ++ P PA ++
Sbjct: 952 PGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPK 1011
Query: 58 RGDSETDLEALFNAVMNPKTANVPQTVPMRLRKLPDSFFKPPEPKSHSRQASTDAGTAGA 117
+ T P + T + LP K P+P+S T+ G+
Sbjct: 1012 AEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTEL-NIGS 1070
Query: 118 LTPQHVRAHSS--------------------------------PASLQLGAVSPGTLTPT 145
P + + S QLG + P+
Sbjct: 1071 KDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPS 1130
Query: 146 GVVSGPAATPTAQHLRQSSFEIPDDVPLPAGWEMAKTSSGQRYFLNHIDQT--------- 196
G + P PT ++++ +P V L E + ++ L + +T
Sbjct: 1131 GPKASPMPVPTESSSQKTA--VPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPM 1188
Query: 197 -TTWQDPRKAMLSQMNVTA-PTSPPVQQNMMNSASAMNQRISQSAPVKQPPPLAPQSPQG 254
TT Q ++ L + +A P+ + R + P+ + P+ +
Sbjct: 1189 VTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKK- 1247
Query: 255 GVMGGSNSNQQQQMRLQQLQMEKERLRLKQQELLRQVRPQELALRSQLPTLEQDGGTQNP 314
++ + ++ ++ Q+ + K ++++ +++L +V P+ + Q T + + P
Sbjct: 1248 -LLPEAKTSAPEE---QKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTP 1303
Query: 315 VSSPGMSQELRTMTTNSSDPFLNSGTYH-----SRDESTDSGLSMSSYSVPRTPDDFLNS 369
S P + P + + E D SS P++P
Sbjct: 1304 QSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGL--- 1360
Query: 370 VDEMDTGDTINQSTLPSQQNRFPDYLEAIPGTNVD-LGTLEGDGMNIEGEELMPSLQEAL 428
DTG + + S P IP D L L+ D + E PS L
Sbjct: 1361 ---SDTG--YSSDGISSSLGEIP---SLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKL 1412
Query: 429 SSDILNDME---SVLAATKLDKES 449
S +L+ +E S LA K +K++
Sbjct: 1413 ESTVLSILEAQASTLADEKSEKKT 1436
Score = 39.7 bits (91), Expect = 0.006
Identities = 47/182 (25%), Positives = 58/182 (31%), Gaps = 29/182 (15%)
Query: 1 MDPGQQPPPQPAPQGQGQPPSQPPQGQGPPSGPGQPAPAATQAAPQAPPAGHQIVHVRGD 60
+D QPPP P P PP PP PP P P P T P P V
Sbjct: 2399 LDISAQPPPPPPP----PPPPPPP----PPPPPPPPLPPPTSPKPTILPKKKLTV---AS 2447
Query: 61 SETDLEALFNAVMNPKTANV---------------PQTVPMRLRKLPDS--FFKPPEPKS 103
T LF+AV +T V P VP + +P F PEP
Sbjct: 2448 PVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSK 2507
Query: 104 HSRQASTDAGTAGALTPQHVRAHSSPASLQLGAVSPGTLTPTGVVSGPAAT-PTAQHLRQ 162
T + H P L L + L + P+ T P + H +
Sbjct: 2508 PPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNK 2567
Query: 163 SS 164
SS
Sbjct: 2568 SS 2569
Score = 35.4 bits (80), Expect = 0.11
Identities = 23/58 (39%), Positives = 25/58 (43%), Gaps = 10/58 (17%)
Query: 3 PGQQPPPQPAPQGQGQPPSQP------PQGQG---PPS-GPGQPAPAATQAAPQAPPA 50
PG PP P PP QP PQ G PPS PG P+A Q +P P A
Sbjct: 494 PGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSA 551
Score = 35.0 bits (79), Expect = 0.14
Identities = 23/50 (46%), Positives = 27/50 (54%), Gaps = 5/50 (10%)
Query: 3 PGQQP-PPQPAPQ--GQGQPPSQPPQGQGPPSGPGQPAPAATQAAPQAPP 49
P QQP P +P+PQ G +PPSQ P G PS QP+PA A P
Sbjct: 510 PPQQPGPAKPSPQQPGSTKPPSQQP-GSAKPSAQ-QPSPAKPSAQQSTKP 557
Score = 34.7 bits (78), Expect = 0.18
Identities = 67/272 (24%), Positives = 92/272 (33%), Gaps = 47/272 (17%)
Query: 6 QPPPQPA--------PQGQGQPPSQPPQGQGPPSGPGQPA-PAATQAAPQAP----PAGH 52
+PP QP+ G +PP QPP PP+ P PA P A Q + P P
Sbjct: 330 KPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPK 389
Query: 53 QIVHVRGDSETDLEALFNAVMNPKTANVPQTVPMRLR-------KLPDSFFKPPEPKSHS 105
+ G +T + A P T V P+ + K P P +
Sbjct: 390 ALAQPPGVGKTPAQQPGPA--KPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPG 447
Query: 106 RQASTDAGTAGALTPQHVRAHSSPASLQLGAVSPGTLTPTGVVSGPAATPTAQ--HLRQS 163
+ + AG G + Q P+ L PG P GPA P Q +
Sbjct: 448 KIPAQQAG-PGKTSAQQTGPTKPPSQL------PGPAKPPPQQPGPAKPPPQQPGSAKPP 500
Query: 164 SFEIPDDVPLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPRKAMLSQMNVTAPTSPPVQQN 223
S + P P AK S Q Q P A S +P P QQ+
Sbjct: 501 SQQPGSTKPPPQQPGPAKPSPQQPG-----STKPPSQQPGSAKPSAQQ-PSPAKPSAQQS 554
Query: 224 MMNSASAMNQRISQSAPVK--QPPPLAPQSPQ 253
+ +SQ+ K QPP ++P + Q
Sbjct: 555 --------TKPVSQTGSGKPLQPPTVSPSAKQ 578
>gi|110347429 mediator complex subunit 12 [Homo sapiens]
Length = 2177
Score = 49.7 bits (117), Expect = 6e-06
Identities = 79/359 (22%), Positives = 127/359 (35%), Gaps = 54/359 (15%)
Query: 3 PGQQPPP---QPAPQGQGQPPSQPP-QGQGPPSGPGQPAPAATQAAPQAPPAGHQIVHVR 58
PG PP + +G+ SQP + + GPG+ P P + H
Sbjct: 1772 PGAAPPSTEERKKKSTKGKKRSQPATKTEDYGMGPGRSGPYGVTVPPDL------LHHPN 1825
Query: 59 GDSETDLEALFNAV-----MNPKTANVPQTVPMRLRKLPDSFFKPPEPKSHSRQASTDAG 113
S T L ++ P A P+ P R +LP P P +T G
Sbjct: 1826 PGSITHLNYRQGSIGLYTQNQPLPAGGPRVDPYRPVRLPMQKL-PTRPTYPGVLPTTMTG 1884
Query: 114 TAGALTP------------------QHVRAHSSPASLQLGAVSPGTLTPT---GVVSGPA 152
G L P Q +R + LG S +TP+ G+ +
Sbjct: 1885 VMG-LEPSSYKTSVYRQQQPAVPQGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQG 1943
Query: 153 ATPTAQH--LRQSSFEIPDDVPLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPRKAMLSQM 210
TP H L+Q + PAG + + S Q Y H T DP + + +
Sbjct: 1944 YTPYVSHVGLQQHTG--------PAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRP 1995
Query: 211 NVTAPTSPPVQQNMMNSASAMNQRISQSAP-VKQPPPLAPQSPQGGVMGGS-----NSNQ 264
+ P + + S + + Q P + P++ Q Q GV + Q
Sbjct: 1996 SGYVHQQAPTYGHGLTSTQRFSHQTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQ 2055
Query: 265 QQQMRLQQLQMEKERLRLKQQELLRQVRPQELALRSQLPTLEQDGGTQNPVSSPGMSQE 323
QQQ + QQ Q ++++ + +QQ +RQ + Q++ + Q +Q Q Q+
Sbjct: 2056 QQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQ 2114
Score = 41.2 bits (95), Expect = 0.002
Identities = 75/336 (22%), Positives = 125/336 (37%), Gaps = 40/336 (11%)
Query: 21 SQPPQGQGPPSGPGQPAPAATQAAPQAPP-AGHQIVHVRGDSETDLEALFNAVMNPKTAN 79
+QP GP P +P Q P P G + G + + +V +
Sbjct: 1845 NQPLPAGGPRVDPYRPVRLPMQKLPTRPTYPGVLPTTMTGVMGLEPSSYKTSVYRQQQPA 1904
Query: 80 VPQTVPMRLRKLPDSFFKPPEPKSHSRQASTDAGTAGALTPQHVRAHSSPASLQLGAVSP 139
VPQ +R ++L S + H T + + G T Q + S LQ
Sbjct: 1905 VPQGQRLR-QQLQQSQGMLGQSSVHQM---TPSSSYGLQTSQGYTPYVSHVGLQQHTGPA 1960
Query: 140 GTLTPTGVVSGP------AATPT----AQHLRQSSFEIPDDVPLPAGW--EMAKT----- 182
GT+ P S P + PT +HL+Q P+G+ + A T
Sbjct: 1961 GTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQR----------PSGYVHQQAPTYGHGL 2010
Query: 183 SSGQRYFLNHIDQTT--TWQDPRKAMLSQMNVTAPTSPPVQQNMMNSASAMNQRISQSAP 240
+S QR+ + QT + P A Q V + P QQ Q+ Q
Sbjct: 2011 TSTQRFSHQTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQ 2070
Query: 241 VKQPPPLAPQSPQGGVMGGSNSNQQQQMRLQQLQMEKERLRLK---QQELLRQVRPQELA 297
+Q + Q + QQQQ + QQ Q ++++ + + QQ+ +Q P +
Sbjct: 2071 QQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQ 2130
Query: 298 LRSQLPTLEQDG--GTQNPVSSPGMSQELRTMTTNS 331
+SQ P ++ G TQ + + ++L+ +N+
Sbjct: 2131 PQSQ-PQFQRQGLQQTQQQQQTAALVRQLQQQLSNT 2165
>gi|238859557 regulatory factor X1 [Homo sapiens]
Length = 979
Score = 49.3 bits (116), Expect = 7e-06
Identities = 95/397 (23%), Positives = 145/397 (36%), Gaps = 72/397 (18%)
Query: 3 PGQQPPPQPAPQGQGQPPSQP----PQGQGPPSGPGQPAP----AATQAAPQAPPAGHQI 54
P PPQ PQ Q QPP P PQ PP+ P P PQA P G Q
Sbjct: 13 PPPSQPPQAPPQAQPQPPPPPPPAAPQPPQPPTAAATPQPQYVTELQSPQPQAQPPGGQK 72
Query: 55 VHVRGDSETDLEALFNAVMNPKTANVPQTVPMR--LRKLPDSFFKPPEPKSHSRQASTDA 112
+V T+L A+ A P A P P + + + + + E S + ST A
Sbjct: 73 QYV-----TELPAV-PAPSQPTGAPTPSPAPQQYIVVTVSEGAMRASETVSEASPGST-A 125
Query: 113 GTAGALTP--QHVRAHSSPASLQLGA-VSPGTLTP---TGVVSGPAATPTAQHLRQSSFE 166
G T Q V+ +Q PG ++P T + A PT + + QS+
Sbjct: 126 SQTGVPTQVVQQVQGTQQRLLVQTSVQAKPGHVSPLQLTNIQVPQQALPTQRLVVQSA-- 183
Query: 167 IPDDVPLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPRKAMLSQMNVTAPTSPPVQQNMMN 226
P G +++ T G + + +Q+ + S APT QQ ++
Sbjct: 184 ----APGSKGGQVSLTVHGTQQVHSPPEQSPVQANSS----SSKTAGAPTGTVPQQLQVH 235
Query: 227 SASAMNQRISQSAPVKQPPPLAPQSPQGGVMGGSNSNQQQQMRLQQLQMEKERLRLKQQE 286
+ QS PV Q + +PQ G Q ++ + E ++L QQ
Sbjct: 236 G-------VQQSVPVTQERSVVQATPQAPKPGPVQPLTVQGLQPVHVAQEVQQL---QQV 285
Query: 287 LLRQVRPQEL-------------ALRS------QLPTLEQD--------GGTQNPVSSPG 319
+ V ++ A+RS + P Q GT VS+P
Sbjct: 286 PVPHVYSSQVQYVEGGDASYTASAIRSSTYSYPETPLYTQTASTSYYEAAGTATQVSTPA 345
Query: 320 MSQELRTMTTNSSDPFLNSGTYHSRDESTDSGLSMSS 356
SQ + ++ S +++ + ST +G S SS
Sbjct: 346 TSQAV--ASSGSMPMYVSGSQVVASSTSTGAGASNSS 380
>gi|27436957 membrane associated guanylate kinase, WW and PDZ domain
containing 2 [Homo sapiens]
Length = 1455
Score = 49.3 bits (116), Expect = 7e-06
Identities = 46/182 (25%), Positives = 63/182 (34%), Gaps = 33/182 (18%)
Query: 28 GPPSGPGQPAPAATQAAPQAPPAGHQIVHVRGDSETDLEALFNAVMNPKTANVPQTVPMR 87
G P P +PAP Q P + +V N + A++
Sbjct: 184 GTPKPPAEPAPLLLNVTDQILPGATPSAEGKRKRN-------KSVSNMEKASI------- 229
Query: 88 LRKLPDSFFKPPEPKSHSRQASTDAGTAGALTPQHVRAHSSPASLQLGAVSPGTLTPTGV 147
+PPE + R G +TP+ A P P V
Sbjct: 230 ---------EPPEEEEEERPVVNGNGVV--VTPESSEHEDKSAGAS--GEMPSQPYPAPV 276
Query: 148 VSGPAATPT----AQHLRQSSFEIPDDVPLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPR 203
S P + + E PD PLP WEMA T G+ YF++H +TT+W DPR
Sbjct: 277 YSQPEELKEQMDDTKPTKPEDNEEPD--PLPDNWEMAYTEKGEVYFIDHNTKTTSWLDPR 334
Query: 204 KA 205
A
Sbjct: 335 LA 336
Score = 32.0 bits (71), Expect = 1.2
Identities = 15/47 (31%), Positives = 24/47 (51%), Gaps = 2/47 (4%)
Query: 206 MLSQMNVTAPTSPPVQQNMMNSASAMNQRISQSAPVKQPPPLAPQSP 252
++ Q + +PTS P + S A ++Q +P+ QP P P SP
Sbjct: 1006 IIPQEELNSPTSAPSSEKQ--SPMAQQSPLAQQSPLAQPSPATPNSP 1050
>gi|94536811 NEDD4-like ubiquitin-protein ligase 1 [Homo sapiens]
Length = 1606
Score = 48.9 bits (115), Expect = 9e-06
Identities = 31/137 (22%), Positives = 60/137 (43%), Gaps = 8/137 (5%)
Query: 170 DVPLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPRKAMLSQMNVTAPTSPPVQQNMMNSAS 229
D PLP WE S G+ ++++H+++TTTWQ P A + + ++Q +
Sbjct: 828 DEPLPPNWEARIDSHGRVFYVDHVNRTTTWQRPTAAATPDGMRRSGSIQQMEQLNRRYQN 887
Query: 230 AMNQRISQSAPVKQPPPLAPQSPQGGVMGGSNSNQQQQMRLQQLQMEKERLRLKQQELLR 289
++ + Q+P GG GG + ++ + + L L+++ L
Sbjct: 888 IQRTIATERSEEDSGSQSCEQAPAGGGGGGGSDSEAES--------SQSSLDLRREGSLS 939
Query: 290 QVRPQELALRSQLPTLE 306
V Q++ L Q P ++
Sbjct: 940 PVNSQKITLLLQSPAVK 956
Score = 35.0 bits (79), Expect = 0.14
Identities = 13/31 (41%), Positives = 20/31 (64%)
Query: 173 LPAGWEMAKTSSGQRYFLNHIDQTTTWQDPR 203
LP GWE+ G+ +F++H + TT+ DPR
Sbjct: 1020 LPRGWEIKTDQQGKSFFVDHNSRATTFIDPR 1050
>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
Length = 2285
Score = 48.5 bits (114), Expect = 1e-05
Identities = 73/300 (24%), Positives = 104/300 (34%), Gaps = 44/300 (14%)
Query: 5 QQPPPQPAPQGQGQPP-----SQPPQGQGPPSGPGQPAPAATQAAPQA-PPAGHQIVHVR 58
QQP QP QPP SQPP Q P P Q + TQ PQ+ PP
Sbjct: 502 QQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQ--QSTTQQHPQSQPPYSQPQAQSP 559
Query: 59 GDSETDLEALFNAVMNPKTANVPQTVPMRLRKLPDSFFKPPEP------KSHSRQASTDA 112
+ + + + PQ+ + F PP+ S + A +
Sbjct: 560 YQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMT 619
Query: 113 GTAGALTPQHVRAHSSPASL-------------QLGAVSPGTLT-----PTGVVSGPAAT 154
+ G ++ S P+SL GA+SPG T G S PA +
Sbjct: 620 SSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQS 679
Query: 155 PTAQHLRQSSFEIPDDVPLPAG--WEMAKTSSGQRYFLNHIDQTTTWQDPRKAMLSQMNV 212
P + H I P P G +A++ SG L+ PR ++
Sbjct: 680 PFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGP---LSPAAVPGNQMPPRPPSGQSDSI 736
Query: 213 TAPTSPPVQQNMMNSASAMNQRISQSAPVKQPPP---LAPQSPQGG-VMGGSNSNQQQQM 268
P+ + Q+ + QR Q P P L+P+ P GG + G S QQ M
Sbjct: 737 MHPS---MNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSM 793
Score = 37.7 bits (86), Expect = 0.022
Identities = 58/260 (22%), Positives = 89/260 (34%), Gaps = 39/260 (15%)
Query: 9 PQPAPQGQGQPPSQPPQGQGPPSGPGQPAPAATQAAPQAPPAGHQ--IVHVRGDSETDLE 66
P P+P G P+ Q + SGP PA P PP+G I+H + + +
Sbjct: 695 PSPSPVGS---PASVAQSR---SGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQ 748
Query: 67 ALFNAVMNPKTANVPQTVPMRLRKLPDSFFKPPEPKS---HSRQASTDAGTAGALTPQ-- 121
NP+ +P P S P +P H+ S + G+ PQ
Sbjct: 749 DRGYMQRNPQ-------MPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGG 801
Query: 122 -HVRAHSSPASLQLGAVSPGTLTPTGVVSG--PAATPTAQHLRQSSFEIPDDVPLPAGWE 178
+ P A+ G+ G P H + IP LP G
Sbjct: 802 QYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPG---IPPYGTLPPG-R 857
Query: 179 MAKTSSGQRYFLNHIDQTTTWQDPRKAMLSQMNVTAPTSPPVQQNMMNSASAMNQRISQS 238
M+ S G R + P A + + PP N +A+ ++ +
Sbjct: 858 MSHASMGNRPY-----------GPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAAN 906
Query: 239 APVKQPPPLAPQSPQGGVMG 258
+ ++ PP P QGG+MG
Sbjct: 907 S-IQNRPPGYPNMNQGGMMG 925
Score = 31.2 bits (69), Expect = 2.0
Identities = 19/47 (40%), Positives = 22/47 (46%), Gaps = 1/47 (2%)
Query: 5 QQPPPQPAPQGQGQPPSQPPQGQGPPSGPGQPAPAATQAAPQAPPAG 51
Q PP QP P Q Q +QP Q + G PA AA + PAG
Sbjct: 1404 QLPPAQPQPASQ-QQAAQPSPQQDVYNQYGNAYPATATAATERRPAG 1449
>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
Length = 2068
Score = 48.5 bits (114), Expect = 1e-05
Identities = 73/300 (24%), Positives = 104/300 (34%), Gaps = 44/300 (14%)
Query: 5 QQPPPQPAPQGQGQPP-----SQPPQGQGPPSGPGQPAPAATQAAPQA-PPAGHQIVHVR 58
QQP QP QPP SQPP Q P P Q + TQ PQ+ PP
Sbjct: 502 QQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQ--QSTTQQHPQSQPPYSQPQAQSP 559
Query: 59 GDSETDLEALFNAVMNPKTANVPQTVPMRLRKLPDSFFKPPEP------KSHSRQASTDA 112
+ + + + PQ+ + F PP+ S + A +
Sbjct: 560 YQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMT 619
Query: 113 GTAGALTPQHVRAHSSPASL-------------QLGAVSPGTLT-----PTGVVSGPAAT 154
+ G ++ S P+SL GA+SPG T G S PA +
Sbjct: 620 SSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQS 679
Query: 155 PTAQHLRQSSFEIPDDVPLPAG--WEMAKTSSGQRYFLNHIDQTTTWQDPRKAMLSQMNV 212
P + H I P P G +A++ SG L+ PR ++
Sbjct: 680 PFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGP---LSPAAVPGNQMPPRPPSGQSDSI 736
Query: 213 TAPTSPPVQQNMMNSASAMNQRISQSAPVKQPPP---LAPQSPQGG-VMGGSNSNQQQQM 268
P+ + Q+ + QR Q P P L+P+ P GG + G S QQ M
Sbjct: 737 MHPS---MNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSM 793
Score = 37.7 bits (86), Expect = 0.022
Identities = 58/260 (22%), Positives = 89/260 (34%), Gaps = 39/260 (15%)
Query: 9 PQPAPQGQGQPPSQPPQGQGPPSGPGQPAPAATQAAPQAPPAGHQ--IVHVRGDSETDLE 66
P P+P G P+ Q + SGP PA P PP+G I+H + + +
Sbjct: 695 PSPSPVGS---PASVAQSR---SGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQ 748
Query: 67 ALFNAVMNPKTANVPQTVPMRLRKLPDSFFKPPEPKS---HSRQASTDAGTAGALTPQ-- 121
NP+ +P P S P +P H+ S + G+ PQ
Sbjct: 749 DRGYMQRNPQ-------MPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGG 801
Query: 122 -HVRAHSSPASLQLGAVSPGTLTPTGVVSG--PAATPTAQHLRQSSFEIPDDVPLPAGWE 178
+ P A+ G+ G P H + IP LP G
Sbjct: 802 QYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPG---IPPYGTLPPG-R 857
Query: 179 MAKTSSGQRYFLNHIDQTTTWQDPRKAMLSQMNVTAPTSPPVQQNMMNSASAMNQRISQS 238
M+ S G R + P A + + PP N +A+ ++ +
Sbjct: 858 MSHASMGNRPY-----------GPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAAN 906
Query: 239 APVKQPPPLAPQSPQGGVMG 258
+ ++ PP P QGG+MG
Sbjct: 907 S-IQNRPPGYPNMNQGGMMG 925
>gi|19924099 synapsin I isoform Ia [Homo sapiens]
Length = 705
Score = 48.5 bits (114), Expect = 1e-05
Identities = 58/188 (30%), Positives = 73/188 (38%), Gaps = 37/188 (19%)
Query: 4 GQQPPPQPAPQGQ--GQPPSQPPQGQGPP--SGPGQPAPAATQAAP----QAPPAGHQIV 55
GQ P P P G+ Q P+ PP Q PP GP QP P + P + PP G Q
Sbjct: 434 GQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQ-- 491
Query: 56 HVRGDSETDLEALFNAVMNPKTANVPQTV--PMRLRKLPDSFFKPPEPKSHSRQASTDAG 113
H+ G + P + +PQ + P + P S PP + RQ+ AG
Sbjct: 492 HLSG------------LGPPAGSPLPQRLPSPTSAPQQPASQAAPP-TQGQGRQSRPVAG 538
Query: 114 TAGALTPQHVRAHSSPASLQLGAVSPGTLTPTGVVSGPA-----ATPTAQHLRQSSFEIP 168
GA P R +SP+ + P T VSGPA P RQ P
Sbjct: 539 GPGA--PPAARPPASPSPQR--QAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGP---P 591
Query: 169 DDVPLPAG 176
P PAG
Sbjct: 592 QKPPGPAG 599
Score = 48.1 bits (113), Expect = 2e-05
Identities = 49/174 (28%), Positives = 61/174 (35%), Gaps = 25/174 (14%)
Query: 3 PGQQPPPQPAPQGQGQPPSQPPQGQGPPSGPGQPAPAATQAAPQAPPAGHQIVHVRGDSE 62
P + P P APQ + P QGQG S P P A AA PPA G +
Sbjct: 505 PQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAA--RPPASPSPQRQAGPPQ 562
Query: 63 TDLEALFNAVMNPKTANVPQTVPMRLRKLPDSFFKPPEPKSHSRQASTDAGTAGALTPQH 122
+ + PK + P R + P KPP P +RQAS AG P
Sbjct: 563 ATRQTSVSGPAPPKASGAPPGGQQR--QGPPQ--KPPGPAGPTRQAS-QAGPVPRTGP-- 615
Query: 123 VRAHSSPASLQLGAVSPGTLTPTGVVSGPAATPTAQHLRQSSFEIPDDVPLPAG 176
P T P GPA P Q ++ S ++P AG
Sbjct: 616 ----------------PTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAG 653
Score = 33.5 bits (75), Expect = 0.41
Identities = 17/47 (36%), Positives = 21/47 (44%)
Query: 5 QQPPPQPAPQGQGQPPSQPPQGQGPPSGPGQPAPAATQAAPQAPPAG 51
Q+P P P P G P + P G APAA+ AAP +G
Sbjct: 26 QRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSG 72
>gi|19924097 synapsin I isoform Ib [Homo sapiens]
Length = 669
Score = 48.5 bits (114), Expect = 1e-05
Identities = 58/188 (30%), Positives = 73/188 (38%), Gaps = 37/188 (19%)
Query: 4 GQQPPPQPAPQGQ--GQPPSQPPQGQGPP--SGPGQPAPAATQAAP----QAPPAGHQIV 55
GQ P P P G+ Q P+ PP Q PP GP QP P + P + PP G Q
Sbjct: 434 GQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQ-- 491
Query: 56 HVRGDSETDLEALFNAVMNPKTANVPQTV--PMRLRKLPDSFFKPPEPKSHSRQASTDAG 113
H+ G + P + +PQ + P + P S PP + RQ+ AG
Sbjct: 492 HLSG------------LGPPAGSPLPQRLPSPTSAPQQPASQAAPP-TQGQGRQSRPVAG 538
Query: 114 TAGALTPQHVRAHSSPASLQLGAVSPGTLTPTGVVSGPA-----ATPTAQHLRQSSFEIP 168
GA P R +SP+ + P T VSGPA P RQ P
Sbjct: 539 GPGA--PPAARPPASPSPQR--QAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGP---P 591
Query: 169 DDVPLPAG 176
P PAG
Sbjct: 592 QKPPGPAG 599
Score = 48.1 bits (113), Expect = 2e-05
Identities = 49/174 (28%), Positives = 61/174 (35%), Gaps = 25/174 (14%)
Query: 3 PGQQPPPQPAPQGQGQPPSQPPQGQGPPSGPGQPAPAATQAAPQAPPAGHQIVHVRGDSE 62
P + P P APQ + P QGQG S P P A AA PPA G +
Sbjct: 505 PQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAA--RPPASPSPQRQAGPPQ 562
Query: 63 TDLEALFNAVMNPKTANVPQTVPMRLRKLPDSFFKPPEPKSHSRQASTDAGTAGALTPQH 122
+ + PK + P R + P KPP P +RQAS AG P
Sbjct: 563 ATRQTSVSGPAPPKASGAPPGGQQR--QGPPQ--KPPGPAGPTRQAS-QAGPVPRTGP-- 615
Query: 123 VRAHSSPASLQLGAVSPGTLTPTGVVSGPAATPTAQHLRQSSFEIPDDVPLPAG 176
P T P GPA P Q ++ S ++P AG
Sbjct: 616 ----------------PTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAG 653
Score = 33.5 bits (75), Expect = 0.41
Identities = 17/47 (36%), Positives = 21/47 (44%)
Query: 5 QQPPPQPAPQGQGQPPSQPPQGQGPPSGPGQPAPAATQAAPQAPPAG 51
Q+P P P P G P + P G APAA+ AAP +G
Sbjct: 26 QRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSG 72
>gi|210032509 hypothetical protein LOC100130302 [Homo sapiens]
Length = 887
Score = 48.5 bits (114), Expect = 1e-05
Identities = 86/349 (24%), Positives = 131/349 (37%), Gaps = 62/349 (17%)
Query: 7 PPPQPAPQGQGQPPSQPPQGQGPPSGPGQPAPAATQAAPQAPPAGHQI-----VHVRGDS 61
P P AP P + P P A++ P A P I + +R S
Sbjct: 546 PAPAAAPAVAAAPAAAASAAPSHSQKPSVPLIQASRPCPAAQPPTKFIKIAPAIQLRTGS 605
Query: 62 ETDLEALFNAVMNPKTANVPQTVPMRLRKLPDSFFKPPEPKSHSRQASTDAGTAGA---- 117
T L+A+ NV P++ + S FKP + A AG +G+
Sbjct: 606 -TGLKAI----------NVEG--PVQGAQALGSSFKPVQAPGSG--APAPAGISGSDLQS 650
Query: 118 -------LTPQHVRAHSSPASLQLGAVSPGTLTP---------TGVVSGPAATP----TA 157
P V+A SSPA LQ +P L P + V++GP +
Sbjct: 651 SGGPLPDARPGAVQA-SSPAPLQFFLNTPEGLRPLTLLQVPQGSAVLTGPQQQSHQLVSL 709
Query: 158 QHLRQSSFEIPDDVPLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPRKAMLSQMNVTAPTS 217
Q L+Q + P P P G + ++ GQ + + + +P +A P
Sbjct: 710 QQLQQPTAAHPPQ-PGPQGSALGLSTQGQAFPAQQLLKV----NPTRARSGLQ----PQP 760
Query: 218 PPVQQNMMNSASAMNQRIS------QSAPVKQPPPLAPQSPQGGVMGGSNSNQQQQMRLQ 271
P +++ SA Q + Q P QPP L Q PQ Q QQ + Q
Sbjct: 761 QPAVLSLLGSAQVPQQGVQLPSVLRQQQPQPQPPKLQLQ-PQWQPKPRQEQPQSQQQQPQ 819
Query: 272 QLQMEKERLRLKQQELLRQVRPQELALRSQLPTLEQDGGTQNPVSSPGM 320
+Q++ ++LR+ QQ Q++ Q+L + Q P G Q PG+
Sbjct: 820 HIQLQTQQLRVLQQPQHIQLQTQQLRVLQQ-PVFLATGAVQIVQPHPGV 867
Score = 32.0 bits (71), Expect = 1.2
Identities = 36/137 (26%), Positives = 54/137 (39%), Gaps = 17/137 (12%)
Query: 5 QQP----PPQPAPQGQGQPPSQPPQGQGPPSG---PGQPAPAATQAAPQAPPAGHQIVHV 57
QQP PPQP PQG S QGQ P+ P A + PQ PA ++ +
Sbjct: 713 QQPTAAHPPQPGPQGSALGLS--TQGQAFPAQQLLKVNPTRARSGLQPQPQPA---VLSL 767
Query: 58 RGDSETDLEALFNAVMNPKTANVPQTVPMRLRKLPDSFFKPPEPKSHSRQASTDAGTAGA 117
G ++ + + + + PQ P +L+ P P+P+ Q+
Sbjct: 768 LGSAQVPQQGV--QLPSVLRQQQPQPQPPKLQLQPQ---WQPKPRQEQPQSQQQQPQHIQ 822
Query: 118 LTPQHVRAHSSPASLQL 134
L Q +R P +QL
Sbjct: 823 LQTQQLRVLQQPQHIQL 839
>gi|148277037 AP2 associated kinase 1 [Homo sapiens]
Length = 961
Score = 48.5 bits (114), Expect = 1e-05
Identities = 100/461 (21%), Positives = 170/461 (36%), Gaps = 56/461 (12%)
Query: 5 QQPPPQPAPQGQGQPPSQPPQGQGPPSGPGQPAPAATQAAP---------------QAPP 49
Q PP QP PQ Q + P PP Q PS Q PA QA P Q PP
Sbjct: 421 QAPPSQPLPQTQAKQPQAPPTPQQTPSTQAQGLPAQAQATPQHQQQLFLKQQQQQQQPPP 480
Query: 50 AGHQ---IVHVRGDSET-DLEALFNAVMNPKTANVP-QTVPMRLRKLPDSFFKPPEPKSH 104
A Q + + ++T +A+ A P A P + ++L +F++ + +
Sbjct: 481 AQQQPAGTFYQQQQAQTQQFQAVHPATQQPAIAQFPVVSQGGSQQQLMQNFYQQQQQQQQ 540
Query: 105 SRQASTDAGTAGALTPQHVRAHSSPASLQLGAVSPGTLTPTGVVSGPAATPTAQHLRQSS 164
+Q A AL Q + + A+LQ P PAA P ++ +
Sbjct: 541 QQQQQQ---LATALHQQQLM--TQQAALQQKPTMAAGQQPQ---PQPAAAPQPAPAQEPA 592
Query: 165 FEIPDDVPLPAGWEMAKTSSGQRY-FLNHIDQTTTWQDPRKAMLSQMNVTAPTSPPVQQN 223
+ P GQ+ L T + + +LS + +A P ++
Sbjct: 593 IQAPVRQQPKVQTTPPPAVQGQKVGSLTPPSSPKTQRAGHRRILSDVTHSAVFGVPASKS 652
Query: 224 -MMNSASAMNQRISQSAPVKQPPPLAPQSPQGGVMGGSNSNQQQQMRLQQLQMEKERLRL 282
+ A+A +++S P +P++ Q V S + + +L
Sbjct: 653 TQLLQAAAAEASLNKSKSATTTPSGSPRTSQQNVYNPSEGSTWNPFD------DDNFSKL 706
Query: 283 KQQELLRQVRPQELALRSQLPTLEQDGGTQNPVSSPGMSQELRTMTTNSSDPFLNSGTYH 342
+ELL ++ A + E+ GG+ + S + T S ++GT
Sbjct: 707 TAEELLN----KDFAKLGEGKHPEKLGGSAESLIPGFQSTQGDAFATTS----FSAGTAE 758
Query: 343 SR--DESTDSGLSMSSYSVPRTPDDFLNSVDEMDTGDTINQSTLPSQQNRFPDYLEAIPG 400
R ++ DSGL + S S P P ++ +++ I P PD L P
Sbjct: 759 KRKGGQTVDSGLPLLSVSDPFIPLQVPDAPEKL-----IEGLKSPDTSLLLPDLL---PM 810
Query: 401 TNVDLGTLEG--DGMNIEGEELMPSLQEALSSDILNDMESV 439
T+ T + + ++ E L+P L+ + + + ESV
Sbjct: 811 TDPFGSTSDAVIEKADVAVESLIPGLEPPVPQRLPSQTESV 851
Score = 36.2 bits (82), Expect = 0.063
Identities = 64/271 (23%), Positives = 88/271 (32%), Gaps = 47/271 (17%)
Query: 6 QPPPQPAPQGQ--GQPPSQP-PQGQGPPSGPGQPAPAATQAAPQAPPAGHQIVHVRGDSE 62
QPPPQ A G S P P+ Q PPS QP P PQAPP Q +
Sbjct: 397 QPPPQAAGSSNQPGLLASVPQPKPQAPPS---QPLPQTQAKQPQAPPTPQQTPSTQAQG- 452
Query: 63 TDLEALFNAVMNPKTANVPQTVPMRLRKLPDSFFKPPEPKSHSRQASTDAGTAGALTPQH 122
+ + PQ K +P P + + A T A T Q
Sbjct: 453 ----------LPAQAQATPQHQQQLFLKQQQQQQQP--PPAQQQPAGTFYQQQQAQTQQF 500
Query: 123 VRAH---SSPASLQLGAVSPGTLTPTGVVSGPAATPTAQHLRQSSFEIPDDVPLPAGWEM 179
H PA Q VS G + Q L Q+ ++ +
Sbjct: 501 QAVHPATQQPAIAQFPVVSQG--------------GSQQQLMQNFYQQQQQQQQQQQQQQ 546
Query: 180 AKTSSGQRYFLNHIDQTTTWQDPRKAMLSQ---MNVTAPTSPPVQQNMMNSASAMNQRIS 236
T+ Q+ + Q Q P A Q AP P Q+ A+ +
Sbjct: 547 LATALHQQQLMT--QQAALQQKPTMAAGQQPQPQPAAAPQPAPAQE------PAIQAPVR 598
Query: 237 QSAPVKQPPPLAPQSPQGGVMGGSNSNQQQQ 267
Q V+ PP A Q + G + +S + Q+
Sbjct: 599 QQPKVQTTPPPAVQGQKVGSLTPPSSPKTQR 629
Score = 33.1 bits (74), Expect = 0.53
Identities = 22/65 (33%), Positives = 29/65 (44%), Gaps = 12/65 (18%)
Query: 1 MDPGQQPPPQPAPQGQGQPPSQPP-----------QGQGPPSGPGQPAPAAT-QAAPQAP 48
M GQQP PQPA Q P +P Q PP+ GQ + T ++P+
Sbjct: 569 MAAGQQPQPQPAAAPQPAPAQEPAIQAPVRQQPKVQTTPPPAVQGQKVGSLTPPSSPKTQ 628
Query: 49 PAGHQ 53
AGH+
Sbjct: 629 RAGHR 633
Score = 29.6 bits (65), Expect = 5.9
Identities = 30/118 (25%), Positives = 44/118 (37%), Gaps = 15/118 (12%)
Query: 221 QQNMMNSASAMNQRISQSAPVKQPPPLAPQSPQGGVMGGSNSNQQQQMRLQQLQMEKERL 280
Q ++ S + S P+ Q PQ+P S Q + Q +++L
Sbjct: 408 QPGLLASVPQPKPQAPPSQPLPQTQAKQPQAPPTPQQTPSTQAQGLPAQAQATPQHQQQL 467
Query: 281 RLKQQELLRQVRP-----------QELALRSQL----PTLEQDGGTQNPVSSPGMSQE 323
LKQQ+ +Q P Q+ A Q P +Q Q PV S G SQ+
Sbjct: 468 FLKQQQQQQQPPPAQQQPAGTFYQQQQAQTQQFQAVHPATQQPAIAQFPVVSQGGSQQ 525
>gi|222352183 neural precursor cell expressed, developmentally
down-regulated 4-like isoform 2 [Homo sapiens]
Length = 854
Score = 48.1 bits (113), Expect = 2e-05
Identities = 58/243 (23%), Positives = 96/243 (39%), Gaps = 45/243 (18%)
Query: 35 QPAPAATQAAPQAPPAGHQIVHVRGDSETDLEALFNAVMNPKTANVPQTVP----MRLRK 90
+P P+ P+ + V++ GDS AL +P + PQ + RL+
Sbjct: 139 EPEPSEGGDVPEPWETISEEVNIAGDSLG--LALPPPPASPGSRTSPQELSEELSRRLQI 196
Query: 91 LPDSFFKP------PEPKSHSRQASTDAGTAGALTPQHVRAHSSPASLQLGAVSPGTLTP 144
PDS + EP S R S A + H P S G T+T
Sbjct: 197 TPDSNGEQFSSLIQREPSSRLRSCSVTDAVAE-------QGHLPPPSAPAGRARSSTVT- 248
Query: 145 TGVVSGPAATPTAQHLRQSSFEIPDDVPLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPRK 204
G TP+ ++ + LP+GWE K + G+ Y++NH ++TTTW P
Sbjct: 249 ----GGEEPTPSVAYVHTTP-------GLPSGWEERKDAKGRTYYVNHNNRTTTWTRPIM 297
Query: 205 AML---SQMNVTAPTSPPVQQNMMNSASAMNQRISQSAPVK--QPPPLA---------PQ 250
+ + + T + ++ + S + ++ SAP++ + P+ PQ
Sbjct: 298 QLAEDGASGSATNSNNHLIEPQIRRPRSLSSPTVTLSAPLEGAKDSPVRRAVKDTLSNPQ 357
Query: 251 SPQ 253
SPQ
Sbjct: 358 SPQ 360
Score = 47.8 bits (112), Expect = 2e-05
Identities = 25/68 (36%), Positives = 33/68 (48%), Gaps = 7/68 (10%)
Query: 136 AVSPGTLTPTGVVSGPAATPTAQHLRQSSFEIPDDVPLPAGWEMAKTSSGQRYFLNHIDQ 195
AV P P +P QH SF LP GWEM +G+ +F++H +
Sbjct: 348 AVKDTLSNPQSPQPSPYNSPKPQHKVTQSF-------LPPGWEMRIAPNGRPFFIDHNTK 400
Query: 196 TTTWQDPR 203
TTTW+DPR
Sbjct: 401 TTTWEDPR 408
Score = 43.5 bits (101), Expect = 4e-04
Identities = 21/61 (34%), Positives = 33/61 (54%), Gaps = 4/61 (6%)
Query: 159 HLRQSSFEIPDDV-PLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPRKAMLSQMNVTAPTS 217
H+R + P+D+ PLP GWE G+ ++++H + T W+DPR L +T P
Sbjct: 414 HMRSKTSLNPNDLGPLPPGWEERIHLDGRTFYIDHNSKITQWEDPR---LQNPAITGPAV 470
Query: 218 P 218
P
Sbjct: 471 P 471
Score = 40.8 bits (94), Expect = 0.003
Identities = 27/94 (28%), Positives = 47/94 (50%), Gaps = 11/94 (11%)
Query: 162 QSSFEIPDDVPLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPRKAMLSQMNVTAPTSPPVQ 221
Q E+P PLP GWE + G+ Y++NH ++TT W P S M+V++ + ++
Sbjct: 64 QHQEELPPP-PLPPGWEEKVDNLGRTYYVNHNNRTTQWHRP-----SLMDVSSESDNNIR 117
Query: 222 QNMMNSASAMNQRISQSAPVKQPPPLAPQSPQGG 255
Q + A ++R + + L P+ +GG
Sbjct: 118 Q---INQEAAHRRFRSRRHISE--DLEPEPSEGG 146
>gi|222352088 neural precursor cell expressed, developmentally
down-regulated 4-like isoform 4 [Homo sapiens]
Length = 967
Score = 48.1 bits (113), Expect = 2e-05
Identities = 58/243 (23%), Positives = 96/243 (39%), Gaps = 45/243 (18%)
Query: 35 QPAPAATQAAPQAPPAGHQIVHVRGDSETDLEALFNAVMNPKTANVPQTVP----MRLRK 90
+P P+ P+ + V++ GDS AL +P + PQ + RL+
Sbjct: 252 EPEPSEGGDVPEPWETISEEVNIAGDSLG--LALPPPPASPGSRTSPQELSEELSRRLQI 309
Query: 91 LPDSFFKP------PEPKSHSRQASTDAGTAGALTPQHVRAHSSPASLQLGAVSPGTLTP 144
PDS + EP S R S A + H P S G T+T
Sbjct: 310 TPDSNGEQFSSLIQREPSSRLRSCSVTDAVAE-------QGHLPPPSAPAGRARSSTVT- 361
Query: 145 TGVVSGPAATPTAQHLRQSSFEIPDDVPLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPRK 204
G TP+ ++ + LP+GWE K + G+ Y++NH ++TTTW P
Sbjct: 362 ----GGEEPTPSVAYVHTTP-------GLPSGWEERKDAKGRTYYVNHNNRTTTWTRPIM 410
Query: 205 AML---SQMNVTAPTSPPVQQNMMNSASAMNQRISQSAPVK--QPPPLA---------PQ 250
+ + + T + ++ + S + ++ SAP++ + P+ PQ
Sbjct: 411 QLAEDGASGSATNSNNHLIEPQIRRPRSLSSPTVTLSAPLEGAKDSPVRRAVKDTLSNPQ 470
Query: 251 SPQ 253
SPQ
Sbjct: 471 SPQ 473
Score = 47.8 bits (112), Expect = 2e-05
Identities = 25/68 (36%), Positives = 33/68 (48%), Gaps = 7/68 (10%)
Query: 136 AVSPGTLTPTGVVSGPAATPTAQHLRQSSFEIPDDVPLPAGWEMAKTSSGQRYFLNHIDQ 195
AV P P +P QH SF LP GWEM +G+ +F++H +
Sbjct: 461 AVKDTLSNPQSPQPSPYNSPKPQHKVTQSF-------LPPGWEMRIAPNGRPFFIDHNTK 513
Query: 196 TTTWQDPR 203
TTTW+DPR
Sbjct: 514 TTTWEDPR 521
Score = 43.5 bits (101), Expect = 4e-04
Identities = 21/61 (34%), Positives = 33/61 (54%), Gaps = 4/61 (6%)
Query: 159 HLRQSSFEIPDDV-PLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPRKAMLSQMNVTAPTS 217
H+R + P+D+ PLP GWE G+ ++++H + T W+DPR L +T P
Sbjct: 527 HMRSKTSLNPNDLGPLPPGWEERIHLDGRTFYIDHNSKITQWEDPR---LQNPAITGPAV 583
Query: 218 P 218
P
Sbjct: 584 P 584
Score = 40.8 bits (94), Expect = 0.003
Identities = 27/94 (28%), Positives = 47/94 (50%), Gaps = 11/94 (11%)
Query: 162 QSSFEIPDDVPLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPRKAMLSQMNVTAPTSPPVQ 221
Q E+P PLP GWE + G+ Y++NH ++TT W P S M+V++ + ++
Sbjct: 177 QHQEELPPP-PLPPGWEEKVDNLGRTYYVNHNNRTTQWHRP-----SLMDVSSESDNNIR 230
Query: 222 QNMMNSASAMNQRISQSAPVKQPPPLAPQSPQGG 255
Q + A ++R + + L P+ +GG
Sbjct: 231 Q---INQEAAHRRFRSRRHISE--DLEPEPSEGG 259
>gi|222352086 neural precursor cell expressed, developmentally
down-regulated 4-like isoform 1 [Homo sapiens]
Length = 975
Score = 48.1 bits (113), Expect = 2e-05
Identities = 58/243 (23%), Positives = 96/243 (39%), Gaps = 45/243 (18%)
Query: 35 QPAPAATQAAPQAPPAGHQIVHVRGDSETDLEALFNAVMNPKTANVPQTVP----MRLRK 90
+P P+ P+ + V++ GDS AL +P + PQ + RL+
Sbjct: 260 EPEPSEGGDVPEPWETISEEVNIAGDSLG--LALPPPPASPGSRTSPQELSEELSRRLQI 317
Query: 91 LPDSFFKP------PEPKSHSRQASTDAGTAGALTPQHVRAHSSPASLQLGAVSPGTLTP 144
PDS + EP S R S A + H P S G T+T
Sbjct: 318 TPDSNGEQFSSLIQREPSSRLRSCSVTDAVAE-------QGHLPPPSAPAGRARSSTVT- 369
Query: 145 TGVVSGPAATPTAQHLRQSSFEIPDDVPLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPRK 204
G TP+ ++ + LP+GWE K + G+ Y++NH ++TTTW P
Sbjct: 370 ----GGEEPTPSVAYVHTTP-------GLPSGWEERKDAKGRTYYVNHNNRTTTWTRPIM 418
Query: 205 AML---SQMNVTAPTSPPVQQNMMNSASAMNQRISQSAPVK--QPPPLA---------PQ 250
+ + + T + ++ + S + ++ SAP++ + P+ PQ
Sbjct: 419 QLAEDGASGSATNSNNHLIEPQIRRPRSLSSPTVTLSAPLEGAKDSPVRRAVKDTLSNPQ 478
Query: 251 SPQ 253
SPQ
Sbjct: 479 SPQ 481
Score = 47.8 bits (112), Expect = 2e-05
Identities = 25/68 (36%), Positives = 33/68 (48%), Gaps = 7/68 (10%)
Query: 136 AVSPGTLTPTGVVSGPAATPTAQHLRQSSFEIPDDVPLPAGWEMAKTSSGQRYFLNHIDQ 195
AV P P +P QH SF LP GWEM +G+ +F++H +
Sbjct: 469 AVKDTLSNPQSPQPSPYNSPKPQHKVTQSF-------LPPGWEMRIAPNGRPFFIDHNTK 521
Query: 196 TTTWQDPR 203
TTTW+DPR
Sbjct: 522 TTTWEDPR 529
Score = 43.5 bits (101), Expect = 4e-04
Identities = 21/61 (34%), Positives = 33/61 (54%), Gaps = 4/61 (6%)
Query: 159 HLRQSSFEIPDDV-PLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPRKAMLSQMNVTAPTS 217
H+R + P+D+ PLP GWE G+ ++++H + T W+DPR L +T P
Sbjct: 535 HMRSKTSLNPNDLGPLPPGWEERIHLDGRTFYIDHNSKITQWEDPR---LQNPAITGPAV 591
Query: 218 P 218
P
Sbjct: 592 P 592
Score = 40.8 bits (94), Expect = 0.003
Identities = 27/94 (28%), Positives = 47/94 (50%), Gaps = 11/94 (11%)
Query: 162 QSSFEIPDDVPLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPRKAMLSQMNVTAPTSPPVQ 221
Q E+P PLP GWE + G+ Y++NH ++TT W P S M+V++ + ++
Sbjct: 185 QHQEELPPP-PLPPGWEEKVDNLGRTYYVNHNNRTTQWHRP-----SLMDVSSESDNNIR 238
Query: 222 QNMMNSASAMNQRISQSAPVKQPPPLAPQSPQGG 255
Q + A ++R + + L P+ +GG
Sbjct: 239 Q---INQEAAHRRFRSRRHISE--DLEPEPSEGG 267
>gi|222352084 neural precursor cell expressed, developmentally
down-regulated 4-like isoform 2 [Homo sapiens]
Length = 854
Score = 48.1 bits (113), Expect = 2e-05
Identities = 58/243 (23%), Positives = 96/243 (39%), Gaps = 45/243 (18%)
Query: 35 QPAPAATQAAPQAPPAGHQIVHVRGDSETDLEALFNAVMNPKTANVPQTVP----MRLRK 90
+P P+ P+ + V++ GDS AL +P + PQ + RL+
Sbjct: 139 EPEPSEGGDVPEPWETISEEVNIAGDSLG--LALPPPPASPGSRTSPQELSEELSRRLQI 196
Query: 91 LPDSFFKP------PEPKSHSRQASTDAGTAGALTPQHVRAHSSPASLQLGAVSPGTLTP 144
PDS + EP S R S A + H P S G T+T
Sbjct: 197 TPDSNGEQFSSLIQREPSSRLRSCSVTDAVAE-------QGHLPPPSAPAGRARSSTVT- 248
Query: 145 TGVVSGPAATPTAQHLRQSSFEIPDDVPLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPRK 204
G TP+ ++ + LP+GWE K + G+ Y++NH ++TTTW P
Sbjct: 249 ----GGEEPTPSVAYVHTTP-------GLPSGWEERKDAKGRTYYVNHNNRTTTWTRPIM 297
Query: 205 AML---SQMNVTAPTSPPVQQNMMNSASAMNQRISQSAPVK--QPPPLA---------PQ 250
+ + + T + ++ + S + ++ SAP++ + P+ PQ
Sbjct: 298 QLAEDGASGSATNSNNHLIEPQIRRPRSLSSPTVTLSAPLEGAKDSPVRRAVKDTLSNPQ 357
Query: 251 SPQ 253
SPQ
Sbjct: 358 SPQ 360
Score = 47.8 bits (112), Expect = 2e-05
Identities = 25/68 (36%), Positives = 33/68 (48%), Gaps = 7/68 (10%)
Query: 136 AVSPGTLTPTGVVSGPAATPTAQHLRQSSFEIPDDVPLPAGWEMAKTSSGQRYFLNHIDQ 195
AV P P +P QH SF LP GWEM +G+ +F++H +
Sbjct: 348 AVKDTLSNPQSPQPSPYNSPKPQHKVTQSF-------LPPGWEMRIAPNGRPFFIDHNTK 400
Query: 196 TTTWQDPR 203
TTTW+DPR
Sbjct: 401 TTTWEDPR 408
Score = 43.5 bits (101), Expect = 4e-04
Identities = 21/61 (34%), Positives = 33/61 (54%), Gaps = 4/61 (6%)
Query: 159 HLRQSSFEIPDDV-PLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPRKAMLSQMNVTAPTS 217
H+R + P+D+ PLP GWE G+ ++++H + T W+DPR L +T P
Sbjct: 414 HMRSKTSLNPNDLGPLPPGWEERIHLDGRTFYIDHNSKITQWEDPR---LQNPAITGPAV 470
Query: 218 P 218
P
Sbjct: 471 P 471
Score = 40.8 bits (94), Expect = 0.003
Identities = 27/94 (28%), Positives = 47/94 (50%), Gaps = 11/94 (11%)
Query: 162 QSSFEIPDDVPLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPRKAMLSQMNVTAPTSPPVQ 221
Q E+P PLP GWE + G+ Y++NH ++TT W P S M+V++ + ++
Sbjct: 64 QHQEELPPP-PLPPGWEEKVDNLGRTYYVNHNNRTTQWHRP-----SLMDVSSESDNNIR 117
Query: 222 QNMMNSASAMNQRISQSAPVKQPPPLAPQSPQGG 255
Q + A ++R + + L P+ +GG
Sbjct: 118 Q---INQEAAHRRFRSRRHISE--DLEPEPSEGG 146
>gi|222352082 neural precursor cell expressed, developmentally
down-regulated 4-like isoform 2 [Homo sapiens]
Length = 854
Score = 48.1 bits (113), Expect = 2e-05
Identities = 58/243 (23%), Positives = 96/243 (39%), Gaps = 45/243 (18%)
Query: 35 QPAPAATQAAPQAPPAGHQIVHVRGDSETDLEALFNAVMNPKTANVPQTVP----MRLRK 90
+P P+ P+ + V++ GDS AL +P + PQ + RL+
Sbjct: 139 EPEPSEGGDVPEPWETISEEVNIAGDSLG--LALPPPPASPGSRTSPQELSEELSRRLQI 196
Query: 91 LPDSFFKP------PEPKSHSRQASTDAGTAGALTPQHVRAHSSPASLQLGAVSPGTLTP 144
PDS + EP S R S A + H P S G T+T
Sbjct: 197 TPDSNGEQFSSLIQREPSSRLRSCSVTDAVAE-------QGHLPPPSAPAGRARSSTVT- 248
Query: 145 TGVVSGPAATPTAQHLRQSSFEIPDDVPLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPRK 204
G TP+ ++ + LP+GWE K + G+ Y++NH ++TTTW P
Sbjct: 249 ----GGEEPTPSVAYVHTTP-------GLPSGWEERKDAKGRTYYVNHNNRTTTWTRPIM 297
Query: 205 AML---SQMNVTAPTSPPVQQNMMNSASAMNQRISQSAPVK--QPPPLA---------PQ 250
+ + + T + ++ + S + ++ SAP++ + P+ PQ
Sbjct: 298 QLAEDGASGSATNSNNHLIEPQIRRPRSLSSPTVTLSAPLEGAKDSPVRRAVKDTLSNPQ 357
Query: 251 SPQ 253
SPQ
Sbjct: 358 SPQ 360
Score = 47.8 bits (112), Expect = 2e-05
Identities = 25/68 (36%), Positives = 33/68 (48%), Gaps = 7/68 (10%)
Query: 136 AVSPGTLTPTGVVSGPAATPTAQHLRQSSFEIPDDVPLPAGWEMAKTSSGQRYFLNHIDQ 195
AV P P +P QH SF LP GWEM +G+ +F++H +
Sbjct: 348 AVKDTLSNPQSPQPSPYNSPKPQHKVTQSF-------LPPGWEMRIAPNGRPFFIDHNTK 400
Query: 196 TTTWQDPR 203
TTTW+DPR
Sbjct: 401 TTTWEDPR 408
Score = 43.5 bits (101), Expect = 4e-04
Identities = 21/61 (34%), Positives = 33/61 (54%), Gaps = 4/61 (6%)
Query: 159 HLRQSSFEIPDDV-PLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPRKAMLSQMNVTAPTS 217
H+R + P+D+ PLP GWE G+ ++++H + T W+DPR L +T P
Sbjct: 414 HMRSKTSLNPNDLGPLPPGWEERIHLDGRTFYIDHNSKITQWEDPR---LQNPAITGPAV 470
Query: 218 P 218
P
Sbjct: 471 P 471
Score = 40.8 bits (94), Expect = 0.003
Identities = 27/94 (28%), Positives = 47/94 (50%), Gaps = 11/94 (11%)
Query: 162 QSSFEIPDDVPLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPRKAMLSQMNVTAPTSPPVQ 221
Q E+P PLP GWE + G+ Y++NH ++TT W P S M+V++ + ++
Sbjct: 64 QHQEELPPP-PLPPGWEEKVDNLGRTYYVNHNNRTTQWHRP-----SLMDVSSESDNNIR 117
Query: 222 QNMMNSASAMNQRISQSAPVKQPPPLAPQSPQGG 255
Q + A ++R + + L P+ +GG
Sbjct: 118 Q---INQEAAHRRFRSRRHISE--DLEPEPSEGG 146
>gi|168229174 RNA binding motif protein 27 [Homo sapiens]
Length = 1060
Score = 48.1 bits (113), Expect = 2e-05
Identities = 79/309 (25%), Positives = 111/309 (35%), Gaps = 42/309 (13%)
Query: 3 PGQQPPPQPAPQGQGQPPSQPPQGQGPPSGPGQPAPAATQAAPQAPPAGH-----QIVHV 57
PG PPP P P P G GP GPG P P + P GH +V
Sbjct: 321 PGLPPPPPPGMLMPPMPGPGPGPGPGPGPGPG-PGPGPGHSMRLPVPQGHGQPPPSVVLP 379
Query: 58 RGDSETDLEALFNAVMNPKTANVPQTVPMRLRKLPDSFFKPPEPKSHSRQASTDAGTAGA 117
+L N+ P T+ VP + R LP PP P++ T
Sbjct: 380 IPRPPITQSSLINSRDQPGTSAVPNLASVGTR-LP-----PPLPQNL-------LYTVSE 426
Query: 118 LTPQHVRAHSSPAS--LQLGAVSP---GTLTPTGVVSGPAATPTAQHLRQSS-FEIPDDV 171
P + R H + AS LQLG P L P + G + H SS + D
Sbjct: 427 RQPMYSREHGAAASERLQLGTPPPLLAARLVPPRNLMG---SSIGYHTSVSSPTPLVPDT 483
Query: 172 PLPAGWE---MAKTSSGQRYFLNHIDQTTTWQDPRKAMLSQ---------MNVTAPTSPP 219
P G+ + TSSG+ + +T T Q P L+ N+ T PP
Sbjct: 484 YEPDGYNPEAPSITSSGRSQYRQFFSRTQT-QRPNLIGLTSGDMDVNPRAANIVIQTEPP 542
Query: 220 VQQNM-MNSASAMNQRISQSAPVKQPPPLAPQSPQGGVMGGSNSNQQQQMRLQQLQMEKE 278
V ++ N + + S+ + + P G G +N N+ +R Q K
Sbjct: 543 VPVSINSNITRVVLEPDSRKRAMSGLEGPLTKKPWLGKQGNNNQNKPGFLRKNQYTNTKL 602
Query: 279 RLRLKQQEL 287
++ QEL
Sbjct: 603 EVKKIPQEL 611
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.125 0.362
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,522,110
Number of Sequences: 37866
Number of extensions: 1387740
Number of successful extensions: 26516
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 516
Number of HSP's successfully gapped in prelim test: 999
Number of HSP's that attempted gapping in prelim test: 12637
Number of HSP's gapped (non-prelim): 10280
length of query: 454
length of database: 18,247,518
effective HSP length: 106
effective length of query: 348
effective length of database: 14,233,722
effective search space: 4953335256
effective search space used: 4953335256
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.